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Sample records for elevation gain counterbalancing

  1. Elevated CO2 stimulates marsh elevation gain, counterbalancing sea-level rise

    PubMed Central

    Langley, J. Adam; McKee, Karen L.; Cahoon, Donald R.; Cherry, Julia A.; Megonigal, J. Patrick

    2009-01-01

    Tidal wetlands experiencing increased rates of sea-level rise (SLR) must increase rates of soil elevation gain to avoid permanent conversion to open water. The maximal rate of SLR that these ecosystems can tolerate depends partly on mineral sediment deposition, but the accumulation of organic matter is equally important for many wetlands. Plant productivity drives organic matter dynamics and is sensitive to global change factors, such as rising atmospheric CO2 concentration. It remains unknown how global change will influence organic mechanisms that determine future tidal wetland viability. Here, we present experimental evidence that plant response to elevated atmospheric [CO2] stimulates biogenic mechanisms of elevation gain in a brackish marsh. Elevated CO2 (ambient + 340 ppm) accelerated soil elevation gain by 3.9 mm yr?1 in this 2-year field study, an effect mediated by stimulation of below-ground plant productivity. Further, a companion greenhouse experiment revealed that the CO2 effect was enhanced under salinity and flooding conditions likely to accompany future SLR. Our results indicate that by stimulating biogenic contributions to marsh elevation, increases in the greenhouse gas, CO2, may paradoxically aid some coastal wetlands in counterbalancing rising seas. PMID:19325121

  2. Elevated CO2 stimulates marsh elevation gain, counterbalancing sea-level rise.

    PubMed

    Langley, J Adam; McKee, Karen L; Cahoon, Donald R; Cherry, Julia A; Megonigal, J Patrick

    2009-04-14

    Tidal wetlands experiencing increased rates of sea-level rise (SLR) must increase rates of soil elevation gain to avoid permanent conversion to open water. The maximal rate of SLR that these ecosystems can tolerate depends partly on mineral sediment deposition, but the accumulation of organic matter is equally important for many wetlands. Plant productivity drives organic matter dynamics and is sensitive to global change factors, such as rising atmospheric CO(2) concentration. It remains unknown how global change will influence organic mechanisms that determine future tidal wetland viability. Here, we present experimental evidence that plant response to elevated atmospheric [CO(2)] stimulates biogenic mechanisms of elevation gain in a brackish marsh. Elevated CO(2) (ambient + 340 ppm) accelerated soil elevation gain by 3.9 mm yr(-1) in this 2-year field study, an effect mediated by stimulation of below-ground plant productivity. Further, a companion greenhouse experiment revealed that the CO(2) effect was enhanced under salinity and flooding conditions likely to accompany future SLR. Our results indicate that by stimulating biogenic contributions to marsh elevation, increases in the greenhouse gas, CO(2), may paradoxically aid some coastal wetlands in counterbalancing rising seas. PMID:19325121

  3. Elevated CO2 stimulates marsh elevation gain, counterbalancing sea-level rise

    USGS Publications Warehouse

    Langley, J.A.; McKee, K.L.; Cahoon, D.R.; Cherry, J.A.; Megonigala, J.P.

    2009-01-01

    Tidal wetlands experiencing increased rates of sea-level rise (SLR) must increase rates of soil elevation gain to avoid permanent conversion to open water. The maximal rate of SLR that these ecosystems can tolerate depends partly on mineral sediment deposition, but the accumulation of organic matter is equally important for many wetlands. Plant productivity drives organic matter dynamics and is sensitive to global change factors, such as rising atmospheric CO2 concentration. It remains unknown how global change will influence organic mechanisms that determine future tidal wetland viability. Here, we present experimental evidence that plant response to elevated atmospheric [CO2] stimulates biogenic mechanisms of elevation gain in a brackish marsh. Elevated CO2 (ambient 340 ppm) accelerated soil elevation gain by 3.9 mm yr1 in this 2-year field study, an effect mediated by stimulation of below-ground plant productivity. Further, a companion greenhouse experiment revealed that the CO2 effect was enhanced under salinity and flooding conditions likely to accompany future SLR. Our results indicate that by stimulating biogenic contributions to marsh elevation, increases in the greenhouse gas, CO2, may paradoxically aid some coastal wetlands in counterbalancing rising seas.

  4. Prepregnancy Body Mass Index, Gestational Weight Gain, and Elevated Depressive Symptoms in a Hispanic Cohort

    PubMed Central

    Ertel, Karen A.; Silveira, Marushka L.; Pekow, Penelope S.; Dole, Nancy; Markenson, Glenn; Chasan-Taber, Lisa

    2016-01-01

    Objectives Our objective was to assess the associations among prepregnancy Body Mass Index (BMI), gestational weight gain (GWG), and elevated depressive symptoms across pregnancy. Methods We evaluated these associations among 1,090 participants in Proyecto Buena Salud, a prospective cohort study of Hispanic (predominantly Puerto Rican) women in Western Massachusetts. BMI and GWG were self-reported; GWG was classified according to the 2009 Institute of Medicine guidelines. Depressive symptoms were assessed in early, mid-, and late pregnancy using the 10-item Edinburgh Postnatal Depression Scale (EPDS). We defined elevated depressive symptoms as EPDS scores ≥13 and ≥15. Results In multivariable, longitudinal modeling, overweight (25.0 to <30 kg/m2) women had an odds ratio of 0.53 (95% CI [0.31, 0.90]) for EPDS scores ≥13 and 0.51 (95% CI [0.28, 0.91]) for EPDS scores ≥15 compared to normal weight women. We did not observe an association between GWG or an interaction between BMI and GWG, in predicting elevated depressive symptoms. Conclusions Our findings provide preliminary support for an association of prepregnancy overweight status and lower depressive symptoms across pregnancy in Hispanic women. Future research should focus on potential social and cultural differences in perceptions of weight and weight gain in the perinatal period and how these influence psychological health. PMID:25110848

  5. The impact of early morning elevated CO sub 2 on foliar carbon gain

    SciTech Connect

    Hanson, P.J.; Norby, R.J. )

    1990-05-01

    Predawn concentrations of CO{sub 2} in the boundary layer above vegetated landscapes can be as much as 200 {mu}L{sup {minus}1} higher than typical midday concentrations (330-360 {mu}l L{sup {minus}1}). This period of elevated CO{sub 2} lasts up to 3 hours after sunrise. Estimates of daily carbon gain from models of photosynthesis have often assumed constant CO{sub 2} concentrations. Photosynthesis and stomatal conductance models were coupled and used to assess the importance of a diurnal variation in CO{sub 2} concentration. Daily carbon gain estimates based on a constant CO{sub 2} concentration equal to the afternoon average (1,200 to 1,600 h), were as much as 13% less than estimates based on the more realistic diurnal pattern including elevated CO{sub 2} concentrations in the morning. The largest discrepancies in calculated carbon gain (6-13%) occurred for simulated sunny days, and for foliage having a low carboxylation efficiency.

  6. Counterbalancing for Serial Order Carryover Effects in Experimental Condition Orders

    ERIC Educational Resources Information Center

    Brooks, Joseph L.

    2012-01-01

    Reactions of neural, psychological, and social systems are rarely, if ever, independent of previous inputs and states. The potential for serial order carryover effects from one condition to the next in a sequence of experimental trials makes counterbalancing of condition order an essential part of experimental design. Here, a method is proposed

  7. Counterbalancing for Serial Order Carryover Effects in Experimental Condition Orders

    ERIC Educational Resources Information Center

    Brooks, Joseph L.

    2012-01-01

    Reactions of neural, psychological, and social systems are rarely, if ever, independent of previous inputs and states. The potential for serial order carryover effects from one condition to the next in a sequence of experimental trials makes counterbalancing of condition order an essential part of experimental design. Here, a method is proposed…

  8. Sexual conflict is not counterbalanced by good genes in the laboratory Drosophila melanogaster model system.

    PubMed

    Stewart, A D; Hannes, A M; Mirzatuny, A; Rice, W R

    2008-11-01

    Sexual conflict theory is based on the observation that females of many species are harmed through their interactions with males. Direct harm to females, however, can potentially be counterbalanced by indirect genetic benefits, where females make up for a reduction in offspring quantity by an increase in offspring quality through a generic increase in offspring fitness (good genes) and/or one restricted to the context of sexual selection (sexy sons). Here, we quantify the magnitude of the good genes mechanism of indirect benefits in a laboratory-adapted population of Drosophila melanogaster. We find that despite high-standing genetic variance for fitness, females gain at most only a modest benefit through the good genes form of indirect benefits--far too little to counterbalance the direct cost of male-induced harm. PMID:18681915

  9. Attentional Bias to Food Images Associated With Elevated Weight and Future Weight Gain: An fMRI Study

    PubMed Central

    Yokum, Sonja; Ng, Janet; Stice, Eric

    2014-01-01

    Behavioral studies reveal that obese vs. lean individuals show attentional bias to food stimuli. Yet research has not investigated this relation using objective brain imaging or tested whether attentional bias to food stimuli predicts future weight gain, which are important aims given the prominence of food cues in the environment. We used functional magnetic resonance imaging (fMRI) to examine attentional bias in 35 adolescent girls ranging from lean to obese using an attention network task involving food and neutral stimuli. BMI correlated positively with speed of behavioral response to both appetizing food stimuli and unappetizing food stimuli, but not to neutral stimuli. BMI correlated positively with activation in brain regions related to attention and food reward, including the anterior insula/frontal operculum, lateral orbitofrontal cortex (OFC), ventrolateral prefrontal cortex (vlPFC), and superior parietal lobe, during initial orientation to food cues. BMI also correlated with greater activation in the anterior insula/frontal operculum during reallocation of attention to appetizing food images and with weaker activation in the medial OFC and ventral pallidum during reallocation of attention to unappetizing food images. Greater lateral OFC activation during initial orientation to appetizing food cues predicted future increases in BMI. Results indicate that overweight is related to greater attentional bias to food cues and that youth who show elevated reward circuitry responsivity during food cue exposure are at increased risk for weight gain. PMID:21681221

  10. Elevation of metabolic rate by pyrogen administration does not affect the gain of respiratory peripheral chemoreflexes in unanesthetized kittens.

    PubMed

    Watanabe, T; Kumar, P; Hanson, M A

    1998-09-01

    We previously reported that reducing environmental temperature from 30 to 25 degrees C increases the gain of respiratory chemoreflexes. To investigate the role of increased metabolism in mediating the effect on the gain of the respiratory chemoreflex, we compared the respiratory responses, at ca. 26 degrees C to breath-by-breath alternations of inspired gas between air and 14% oxygen (hypoxia run) or air and 5% CO2 (CO2 run) with that to alteration of air between two inspired lines (control run) before and after the injection of a pyrogen (IL-1beta 400 ng/kg i.p.) in eight kittens at 27-35 d of postnatal age. The respiratory chemoreflex was quantified from the alternations in inspiratory and expiratory variables produced during test runs in terms of the direction and the amplitude of the alternation for each variable and compared with the results of control runs at the same temperature. Pyrogen administration produced a rise in rectal temperature and in oxygen consumption. However, there was no difference in the chemoreflex response to hypoxia or CO2 runs, in terms of either the pattern or of the amplitude of alternation, before and after the injection of the pyrogen. We conclude that the increase in the gain of chemoreflex observed during cooling in a previous study is not due to an increase in metabolism. Some change in input from thermoreceptors may bias the gain of chemoreflexes. PMID:9727713

  11. Dietary linoleic acid elevates the endocannabinoids 2-AG and anandamide and promotes weight gain in mice fed a low fat diet.

    PubMed

    Alvheim, Anita Ryneberg; Torstensen, Bente E; Lin, Yu Hong; Lillefosse, Haldis Hauks; Lock, Erik-Jan; Madsen, Lise; Fryland, Livar; Hibbeln, Joseph R; Malde, Marian Kjellevold

    2014-01-01

    Dietary intake of linoleic acid (LNA, 18:2n-6) has increased dramatically during the 20th century and is associated with greater prevalence of obesity. The endocannabinoid system is involved in regulation of energy balance and a sustained hyperactivity of the endocannabinoid system may contribute to obesity. Arachidonic acid (ARA, 20:4n-6) is the precursor for 2-AG and anandamide (AEA), and we sought to determine if low fat diets (LFD) could be made obesogenic by increasing the endocannabinoid precursor pool of ARA, causing excessive endocannabinoid signaling leading to weight gain and a metabolic profile associated with obesity. Mice (C57BL/6j, 6weeks of age) were fed 1en% LNA and 8en% LNA in low fat (12.5en%) and medium fat diets (MFD, 35en%) for 16weeks. We found that increasing dietary LNA from 1 to 8en% in LFD and MFD significantly increased ARA in phospholipids (ARA-PL), elevated 2-AG and AEA in liver, elevated plasma leptin, and resulted in larger adipocytes and more macrophage infiltration in adipose tissue. In LFD, dietary LNA of 8en% increased feed efficiency and caused greater weight gain than in an isocaloric reduction to 1en% LNA. Increasing dietary LNA from 1 to 8en% elevates liver endocannabinoid levels and increases the risk of developing obesity. Thus a high dietary content of LNA (8en%) increases the adipogenic properties of a low fat diet. PMID:24081493

  12. Do elevations in temperature, CO2, and nutrient availability modify belowground carbon gain and root morphology in artificially defoliated silver birch seedlings?

    PubMed

    Huttunen, Liisa; Saravesi, Karita; Markkola, Annamari; Niemelä, Pekka

    2013-09-01

    Climate warming increases the risk of insect defoliation in boreal forests. Losses in photosynthetically active surfaces cause reduction in net primary productivity and often compromise carbon reserves of trees. The concurrent effects of climate change and removal of foliage on root growth responses and carbohydrate dynamics are poorly understood, especially in tree seedlings. We investigated if exposures to different combinations of elevated temperature, CO2, and nutrient availability modify belowground carbon gain and root morphology in artificially defoliated 1-year-old silver birches (Betula pendula). We quantified nonstructural carbohydrates (insoluble starch as a storage compound; soluble sucrose, fructose, and glucose) singly and in combination in fine roots of plants under winter dormancy. Also the total mass, fine root proportion, water content, and length of roots were defined. We hypothesized that the measured properties are lower in defoliated birch seedlings that grow with ample resources than with scarce resources. On average, fertilization markedly decreased both the proportion and the carbohydrate concentrations of fine roots in all seedlings, whereas the effect of fertilization on root water content and dry mass was the opposite. However, defoliation mitigated the effect of fertilization on the root water content, as well as on the proportion of fine roots and their carbohydrate concentrations by reversing the outcomes. Elevation in temperature decreased and elevation in CO2 increased the absolute contents of total nonstructural carbohydrates, whereas fertilization alleviated both these effects. Also the root length and mass increased by CO2 elevation. This confirms that surplus carbon in birch tissues is used as a substrate for storage compounds and for cell wall synthesis. To conclude, our results indicate that some, but not all elements of climate change alter belowground carbon gain and root morphology in defoliated silver birch seedlings. PMID:24101972

  13. Do elevations in temperature, CO2, and nutrient availability modify belowground carbon gain and root morphology in artificially defoliated silver birch seedlings?

    PubMed Central

    Huttunen, Liisa; Saravesi, Karita; Markkola, Annamari; Niemelä, Pekka

    2013-01-01

    Climate warming increases the risk of insect defoliation in boreal forests. Losses in photosynthetically active surfaces cause reduction in net primary productivity and often compromise carbon reserves of trees. The concurrent effects of climate change and removal of foliage on root growth responses and carbohydrate dynamics are poorly understood, especially in tree seedlings. We investigated if exposures to different combinations of elevated temperature, CO2, and nutrient availability modify belowground carbon gain and root morphology in artificially defoliated 1-year-old silver birches (Betula pendula). We quantified nonstructural carbohydrates (insoluble starch as a storage compound; soluble sucrose, fructose, and glucose) singly and in combination in fine roots of plants under winter dormancy. Also the total mass, fine root proportion, water content, and length of roots were defined. We hypothesized that the measured properties are lower in defoliated birch seedlings that grow with ample resources than with scarce resources. On average, fertilization markedly decreased both the proportion and the carbohydrate concentrations of fine roots in all seedlings, whereas the effect of fertilization on root water content and dry mass was the opposite. However, defoliation mitigated the effect of fertilization on the root water content, as well as on the proportion of fine roots and their carbohydrate concentrations by reversing the outcomes. Elevation in temperature decreased and elevation in CO2 increased the absolute contents of total nonstructural carbohydrates, whereas fertilization alleviated both these effects. Also the root length and mass increased by CO2 elevation. This confirms that surplus carbon in birch tissues is used as a substrate for storage compounds and for cell wall synthesis. To conclude, our results indicate that some, but not all elements of climate change alter belowground carbon gain and root morphology in defoliated silver birch seedlings. PMID:24101972

  14. Fundamentals of ionic conductivity relaxation gained from study of procaine hydrochloride and procainamide hydrochloride at ambient and elevated pressure

    NASA Astrophysics Data System (ADS)

    Wojnarowska, Z.; Swiety-Pospiech, A.; Grzybowska, K.; Hawelek, L.; Paluch, M.; Ngai, K. L.

    2012-04-01

    The pharmaceuticals, procaine hydrochloride and procainamide hydrochloride, are glass-forming as well as ionically conducting materials. We have made dielectric measurements at ambient and elevated pressures to characterize the dynamics of the ion conductivity relaxation in these pharmaceuticals, and calorimetric measurements for the structural relaxation. Perhaps due to their special chemical and physical structures, novel features are found in the ionic conductivity relaxation of these pharmaceuticals. Data of conductivity relaxation in most ionic conductors when represented by the electric loss modulus usually show a single resolved peak in the electric modulus loss M?(f ) spectra. However, in procaine hydrochloride and procainamide hydrochloride we find in addition another resolved loss peak at higher frequencies over a temperature range spanning across Tg. The situation is analogous to many non-ionic glass-formers showing the presence of the structural ?-relaxation together with the Johari-Goldstein (JG) ?-relaxation. Naturally the analogy leads us to name the slower and faster processes resolved in procaine hydrochloride and procainamide hydrochloride as the primary ?-conductivity relaxation and the secondary ?-conductivity relaxation, respectively. The analogy of the ?-conductivity relaxation in procaine HCl and procainamide HCl with JG ?-relaxation in non-ionic glass-formers goes further by the finding that the ?-conductivity is strongly related to the ?-conductivity relaxation at temperatures above and below Tg. At elevated pressure but compensated by raising temperature to maintain ?-conductivity relaxation time constant, the data show invariance of the ratio between the ?- and the ?-conductivity relaxation times to changes of thermodynamic condition. This property indicates that the ?-conductivity relaxation has fundamental importance and is indispensable as the precursor of the ?-conductivity relaxation, analogous to the relation found between the Johari-Goldstein ?-relaxation and the structural ?-relaxation in non-ionic glass-forming systems. The novel features of the ionic conductivity relaxation are brought out by presenting the measurements in terms of the electric modulus or permittivity. If presented in terms of conductivity, the novel features are lost. This warns against insisting that a log-log plot of conductivity vs. frequency is optimal to reveal and interpret the dynamics of ionic conductors.

  15. Fundamentals of ionic conductivity relaxation gained from study of procaine hydrochloride and procainamide hydrochloride at ambient and elevated pressure.

    PubMed

    Wojnarowska, Z; Swiety-Pospiech, A; Grzybowska, K; Hawelek, L; Paluch, M; Ngai, K L

    2012-04-28

    The pharmaceuticals, procaine hydrochloride and procainamide hydrochloride, are glass-forming as well as ionically conducting materials. We have made dielectric measurements at ambient and elevated pressures to characterize the dynamics of the ion conductivity relaxation in these pharmaceuticals, and calorimetric measurements for the structural relaxation. Perhaps due to their special chemical and physical structures, novel features are found in the ionic conductivity relaxation of these pharmaceuticals. Data of conductivity relaxation in most ionic conductors when represented by the electric loss modulus usually show a single resolved peak in the electric modulus loss M(")(f) spectra. However, in procaine hydrochloride and procainamide hydrochloride we find in addition another resolved loss peak at higher frequencies over a temperature range spanning across T(g). The situation is analogous to many non-ionic glass-formers showing the presence of the structural α-relaxation together with the Johari-Goldstein (JG) β-relaxation. Naturally the analogy leads us to name the slower and faster processes resolved in procaine hydrochloride and procainamide hydrochloride as the primary α-conductivity relaxation and the secondary β-conductivity relaxation, respectively. The analogy of the β-conductivity relaxation in procaine HCl and procainamide HCl with JG β-relaxation in non-ionic glass-formers goes further by the finding that the β-conductivity is strongly related to the α-conductivity relaxation at temperatures above and below T(g). At elevated pressure but compensated by raising temperature to maintain α-conductivity relaxation time constant, the data show invariance of the ratio between the β- and the α-conductivity relaxation times to changes of thermodynamic condition. This property indicates that the β-conductivity relaxation has fundamental importance and is indispensable as the precursor of the α-conductivity relaxation, analogous to the relation found between the Johari-Goldstein β-relaxation and the structural α-relaxation in non-ionic glass-forming systems. The novel features of the ionic conductivity relaxation are brought out by presenting the measurements in terms of the electric modulus or permittivity. If presented in terms of conductivity, the novel features are lost. This warns against insisting that a log-log plot of conductivity vs. frequency is optimal to reveal and interpret the dynamics of ionic conductors. PMID:22559496

  16. Dopaminergic agonists normalize elevated hypothalamic neuropeptide Y and corticotropin-releasing hormone, body weight gain, and hyperglycemia in ob/ob mice.

    PubMed

    Bina, K G; Cincotta, A H

    2000-01-01

    Hypothalamic neuropeptide Y (NPY) and corticotropin-releasing hormone (CRH) influence feeding and levels of plasma glucose, insulin, free fatty acids, and triglycerides. Treatment of genetically obese, ob/ob mice, with dopamine receptor D(1)/D(2) agonists normalizes hyperphagia, body weight gain, hyperglycemia, and hyperlipidemia. We therefore examined whether levels of NPY and CRH immunoreactivity in discrete hypothalamic nuclei are altered in ob/ob mice, and whether dopaminergic treatment reverses this alteration. Female ob/ob mice were treated daily at 1 h after light onset with the D(1)/D(2) agonists, SKF-38393 (20 mg/kg) and bromocriptine (15 mg/kg), respectively or vehicle for 2 weeks. Such treatment, while normalizing body weight gain and hyperglycemia, also significantly reduced elevated NPY immunoreactivity in the suprachiasmatic (by 39%), intergeniculate (by 43%), paraventricular (PVN; by 31%), and arcuate (by 41%) nuclei in obese mice to levels observed in lean mice. This treatment also caused a 45-50% decline in levels of CRH in the PVN and dorsomedial hypothalamus compared to obese controls to levels observed in lean mice. Taken together, these findings suggest that dopaminergic D(1)/D(2) receptor coactivation may improve hyperphagia, hyperglycemia, and obesity in the ob/ob mouse, in part, by normalizing elevated levels of both NPY and CRH. PMID:10644901

  17. Elevated PDGFRB gene copy number gain is prognostic for improved survival outcomes in resected malignant pleural mesothelioma.

    PubMed

    Tsao, Anne S; Harun, Nusrat; Fujimoto, Junya; Devito, Vikki; Lee, J Jack; Kuhn, Elisabetta; Mehran, Reza; Rice, David; Moran, Cesar; Hong, Waun Ki; Shen, Li; Suraokar, Milind; Wistuba, Ignacio

    2014-06-01

    PDGF/PDGFR pathway has been implicated in malignant pleural mesothelioma (MPM) carcinogenesis, and evidence suggests autocrine mechanisms of proliferation. We sought to evaluate the incidence of PDGFRB gene copy number gain (CNG) by fluorescence in situ hybridization and PDGFR pathway protein expression by immunohistochemistry (IHC) and correlate it to patient clinical outcome. Eighty-eight archived tumor blocks from resected MPM with full clinical information were used to perform IHC biomarkers (PDGFRα, PDGFRβ, p-PDGFRβ) and fluorescence in situ hybridization analysis of PDGFRB gene CNG. Spearman rank correlation, Wilcoxon rank-sum test, Kruskal-Wallis test, BLiP plots, and Kaplan-Meier method were used to analyze the biomarkers and correlation to clinical outcome. Several correlations between the IHC biomarkers were seen; however, none correlated to clinically relevant patient demographics or histology. In the CNG analysis, PDGFRB gene CNG in >10% of tumor cells had lower cytoplasmic p-PDGFRβ (P=.029), while PDGFRB gene CNG in >40% of tumor cells had a higher cytoplasmic PDGFRβ (P=.04). PDGFRB gene CNG status did not associate with patient demographics or tumor characteristics. PDGFR pathway IHC biomarkers did not associate with survival outcomes. However, patients with PDGFRB CNG >40% of tumor cells had improved relapse-free survival (HR 0.25 [95% CI 0.09-0.72], P=.0096) and improved overall survival (HR 0.32 [95% CI 0.11-0.89], P=.029). PDGFRB CNG >40% of MPM tumor cells is a potential prognostic biomarker for surgery and may identify a unique population of mesothelioma patients. Future validation of this biomarker in prospective trials is needed. From a retrospective review of archived tissue specimens from patients with resected malignant pleural mesothelioma tumors, we show that patients with PDGFRB CNG >40% of tumor cells had improved relapse-free survival (HR 0.25 [95% CI 0.09-0.72], P=.0096) and improved overall survival (HR 0.32 [95% CI 0.11-0.89], P=.029). PDGFRB CNG >40% of MPM tumor cells is a potential prognostic biomarker for surgery and may identify a unique population of mesothelioma patients. PMID:24747001

  18. Dynamic counterbalancing the single-piston linear compressor of a Stirling cryogenic cooler

    NASA Astrophysics Data System (ADS)

    Veprik, A.; Nachman, I.; Pundak, N.

    2009-05-01

    Low vibration Stirling cryocoolers often rely on dual-piston linear compressors, the known disadvantages of which, as compared to their single-piston rivals, are: low reliability, increased power consumption, price, bulk, sensitivity to external vibration and g-forces. However, because of the inherently low level of vibration export, as required in numerous vibration sensitive electronic and electro-optic applications, the dual-piston approach has become prevalent in today's industrial practice. The authors report on the novel approach to the passive control of a fundamental component of a vibration export from a single-piston compressor down to the levels typical for the actively controlled dual-piston rival. The technique relies on the newly proposed principle of dynamic counterbalancing, where an auxiliary movable mass is flexibly attached to a movable piston assembly and to the stationary compressor casing using auxiliary mechanical springs. The proper design of such a "spring-mass-spring" counterbalancer yields zero vibration export at minimum electrical power and current consumed by the motor. Based on the theoretical analysis, the design of the single-piston compressor of 1 W@77 K Ricor model K529N Stirling cryocooler was enhanced by adding such a counterbalancer. The obtained experimental results are in full agreement with the theoretical prediction. From experiment, the vibration export at driving frequency was reduced 57-fold at practically the same electrical current and power consumed by the compressor actuator as compared with the basic cooler.

  19. mTOR signaling promotes stem cell activation via counterbalancing BMP-mediated suppression during hair regeneration.

    PubMed

    Deng, Zhili; Lei, Xiaohua; Zhang, Xudong; Zhang, Huishan; Liu, Shuang; Chen, Qi; Hu, Huimin; Wang, Xinyue; Ning, Lina; Cao, Yujing; Zhao, Tongbiao; Zhou, Jiaxi; Chen, Ting; Duan, Enkui

    2015-02-01

    Hair follicles (HFs) undergo cycles of degeneration (catagen), rest (telogen), and regeneration (anagen) phases. Anagen begins when the hair follicle stem cells (HFSCs) obtain sufficient activation cues to overcome suppressive signals, mainly the BMP pathway, from their niche cells. Here, we unveil that mTOR complex 1 (mTORC1) signaling is activated in HFSCs, which coincides with the HFSC activation at the telogen-to-anagen transition. By using both an inducible conditional gene targeting strategy and a pharmacological inhibition method to ablate or inhibit mTOR signaling in adult skin epithelium before anagen initiation, we demonstrate that HFs that cannot respond to mTOR signaling display significantly delayed HFSC activation and extended telogen. Unexpectedly, BMP signaling activity is dramatically prolonged in mTOR signaling-deficient HFs. Through both gain- and loss-of-function studies in vitro, we show that mTORC1 signaling negatively affects BMP signaling, which serves as a main mechanism whereby mTORC1 signaling facilitates HFSC activation. Indeed, in vivo suppression of BMP by its antagonist Noggin rescues the HFSC activation defect in mTORC1-null skin. Our findings reveal a critical role for mTOR signaling in regulating stem cell activation through counterbalancing BMP-mediated repression during hair regeneration. PMID:25609845

  20. Une porte optique intensificatrice picoseconde a gain eleve: Caracterisation et application potentielle en imagerie de petits objets places dans des milieux diffusants

    NASA Astrophysics Data System (ADS)

    Marengo, Stephanie

    Dans cette etude, nous avons developpe un amplificateur a colorant possedant ces deux caracteristiques. Le colorant choisi, l'iodure de 3,3'-dimethyloxatricarbocyanine (methyl-DOTCI), possede un epaulement dans la bande d'absorption a 620 nm ce qui convient bien a notre pompe femtoseconde. De plus, son maximum de fluorescence est a 720 nm ce qui est particulierement interessant dans le cas des etudes avec des tissus biologiques humains. En effet, la fenetre dite "therapeutique" se situe dans les longueurs d'onde rouge et proche infrarouge. Le phenomene d'amplification, qui se produit dans des conditions experimentales precises, est en fait une emission stimulee du colorant qui est largement favorisee par rapport a sa fluorescence naturelle (emission spontanee). L'arrivee du signal incident, dont la longueur d'onde correspond au saut energetique entre l'etat fondamental et l'etat excite ou se trouvent les molecules, provoque une avalanche coherente de celles-ci vers l'etat fondamental generant ainsi l'emission stimulee. Une des conditions necessaires pour l'obtention d'un gain eleve est que la duree de l'impulsion de pompe soit inferieure au temps de relaxation des molecules ainsi qu'inferieure au temps requis pour effectuer un trajet dans la cellule de colorant. Ceci nous a permis d'amplifier un signal incident par un facteur entre 103 et 104. De plus, ce gain eleve n'est observe qu'a l'interieur d'une fenetre temporelle d'environ 10 picosecondes. Nous avons integre cet amplificateur a notre montage de transillumination afin d'acquerir des images d'un patron de lignes opaques immerge dans un milieu diffusant liquide. Des images de lignes ayant une resolution spatiale de 200 mum ont ete obtenues. La cible etait placee au centre d'un melange contenant des proportions variables de lait et d'eau. Deux longueurs de trajet optique dans la solution ont ete utilisees: 30 et 50 mm. Pour determiner les proprietes optiques de notre milieu diffusant, nous avons mis au point une technique de caracterisation basee sur la distribution radiale des photons transmis a travers le milieu. Deux parametres de transport, les coefficients de diffusion effectif (mus') et d'absorption (mu a), caracterisent la forme et l'amplitude du profil radial. Le fit des courbes experimentales a des courbes simulees nous a permis d'extraire ces coefficients. Les courbes simulees ont ete realisees grace a une simulation Monte Carlo qui incorpore les conditions experimentales de notre montage de caracterisation. (Abstract shortened by UMI.)

  1. A contractile and counterbalancing adhesion system controls the 3D shape of crawling cells.

    PubMed

    Burnette, Dylan T; Shao, Lin; Ott, Carolyn; Pasapera, Ana M; Fischer, Robert S; Baird, Michelle A; Der Loughian, Christelle; Delanoe-Ayari, Helene; Paszek, Matthew J; Davidson, Michael W; Betzig, Eric; Lippincott-Schwartz, Jennifer

    2014-04-14

    How adherent and contractile systems coordinate to promote cell shape changes is unclear. Here, we define a counterbalanced adhesion/contraction model for cell shape control. Live-cell microscopy data showed a crucial role for a contractile meshwork at the top of the cell, which is composed of actin arcs and myosin IIA filaments. The contractile actin meshwork is organized like muscle sarcomeres, with repeating myosin II filaments separated by the actin bundling protein ?-actinin, and is mechanically coupled to noncontractile dorsal actin fibers that run from top to bottom in the cell. When the meshwork contracts, it pulls the dorsal fibers away from the substrate. This pulling force is counterbalanced by the dorsal fibers' attachment to focal adhesions, causing the fibers to bend downward and flattening the cell. This model is likely to be relevant for understanding how cells configure themselves to complex surfaces, protrude into tight spaces, and generate three-dimensional forces on the growth substrate under both healthy and diseased conditions. PMID:24711500

  2. A contractile and counterbalancing adhesion system controls the 3D shape of crawling cells

    PubMed Central

    Burnette, Dylan T.; Shao, Lin; Ott, Carolyn; Pasapera, Ana M.; Fischer, Robert S.; Baird, Michelle A.; Der Loughian, Christelle; Delanoe-Ayari, Helene; Paszek, Matthew J.; Davidson, Michael W.; Betzig, Eric

    2014-01-01

    How adherent and contractile systems coordinate to promote cell shape changes is unclear. Here, we define a counterbalanced adhesion/contraction model for cell shape control. Live-cell microscopy data showed a crucial role for a contractile meshwork at the top of the cell, which is composed of actin arcs and myosin IIA filaments. The contractile actin meshwork is organized like muscle sarcomeres, with repeating myosin II filaments separated by the actin bundling protein ?-actinin, and is mechanically coupled to noncontractile dorsal actin fibers that run from top to bottom in the cell. When the meshwork contracts, it pulls the dorsal fibers away from the substrate. This pulling force is counterbalanced by the dorsal fibers attachment to focal adhesions, causing the fibers to bend downward and flattening the cell. This model is likely to be relevant for understanding how cells configure themselves to complex surfaces, protrude into tight spaces, and generate three-dimensional forces on the growth substrate under both healthy and diseased conditions. PMID:24711500

  3. Autoimmune vitiligo is associated with gain-of-function by a transcriptional regulator that elevates expression of HLA-A*02:01 in vivo.

    PubMed

    Hayashi, Masahiro; Jin, Ying; Yorgov, Daniel; Santorico, Stephanie A; Hagman, James; Ferrara, Tracey M; Jones, Kenneth L; Cavalli, Giulio; Dinarello, Charles A; Spritz, Richard A

    2016-02-01

    HLA-A is a class I major histocompatibility complex receptor that presents peptide antigens on the surface of most cells. Vitiligo, an autoimmune disease in which skin melanocytes are destroyed by cognate T cells, is associated with variation in the HLA-A gene; specifically HLA-A*02:01, which presents multiple vitiligo melanocyte autoantigens. Refined genetic mapping localizes vitiligo risk in the HLA-A region to an SNP haplotype ∼20-kb downstream, spanning an ENCODE element with many characteristics of a transcriptional enhancer. Convergent CTCF insulator sites flanking the HLA-A gene promoter and the predicted transcriptional regulator, with apparent interaction between these sites, suggests this element regulates the HLA-A promoter. Peripheral blood mononuclear cells from healthy subjects homozygous for the high-risk haplotype expressed 39% more HLA-A RNA than cells from subjects carrying nonhigh-risk haplotypes (P = 0.0048). Similarly, RNAseq analysis of 1,000 Genomes Project data showed more HLA-A mRNA expressed in subjects homozygous for the high-risk allele of lead SNP rs60131261 than subjects homozygous for the low-risk allele (P = 0.006). Reporter plasmid transfection and genomic run-on sequence analyses confirm that the HLA-A transcriptional regulator contains multiple bidirectional promoters, with greatest activity on the high-risk haplotype, although it does not behave as a classic enhancer. Vitiligo risk associated with the MHC class I region thus derives from combined quantitative and qualitative phenomena: a SNP haplotype in a transcriptional regulator that induces gain-of-function, elevating expression of HLA-A RNA in vivo, in strong linkage disequilibrium with an HLA-A allele that confers *02:01 specificity. PMID:26787886

  4. Genetic and environmental modulation of neurotrophic and anabolic stress response: Counterbalancing forces.

    PubMed

    Taylor, Marcus K; Carpenter, Jennifer; Stone, Michael; Hernandez, Lisa M; Rauh, Mitchell J; Laurent, Heidemarie K; Granger, Douglas A

    2015-11-01

    The serotonin transporter genetic variant 5HTTLPR influences activation and feedback control of the hypothalamic-pituitary-adrenal axis, and has been shown to influence the effect of stressful life events on behavioral health. We recently reported that 5HTTLPR modulates cortisol response in healthy military men exposed to intense stress. Less is known of its combined effects with environmental factors in this context, or of its effect on neuroprotective stress responses. In this follow-up study, we examined the unique and combined effects of 5HTTLPR and prior trauma exposure on neuroprotective (salivary nerve growth factor [sNGF]), anabolic (dehydroepiandrosterone sulfate [DHEAS] and testosterone), and catabolic (cortisol) stress responses. Ninety-three healthy, active-duty military men were studied before, during, and 24h after a stressful 12-day survival course. Distinct and interactive effects of 5HTTLPR long allele carriage [L] versus homozygous short allele carriage [SS]) and prior trauma exposure (low versus high) were evaluated, after which a priori group comparisons were performed between hypothesized high resilience (L/low) and low resilience (SS/high) groups. For sNGF, L/low produced the greatest sNGF throughout stress exposure while SS/high demonstrated the smallest; L/high and SS/low bisected these two extremes and were nearly identical to each other (i.e., SS/high < SS/low = L/high < L/low). Thus, 5HTTLPR and prior trauma exposure demonstrated counterbalancing (additive) forces. Similar patterns were found for DHEAS. To our knowledge, this study is the first to report counterbalancing genetic and environmental effects on novel biomarkers related to resilience in humans exposed to real-world stress. These findings have profound implications for health, performance and training in high-stress occupational settings. PMID:26136163

  5. Moderating the interaction between procedural justice and decision frame: the counterbalancing effect of personality traits.

    PubMed

    Sasaki, Hiroyuki; Hayashi, Yoichiro

    2013-01-01

    This study examined the framing effect of decision making in contexts in which the issue of social justice matters as well as the moderating effects of personality traits on the relationship between justice and framing effects. The authors manipulated procedural justice and outcome valence of the decision frame within two vignettes and measured two personality traits (self-efficacy and anxiety) of participants. The results from 363 participants showed that the moderating effects of personality traits counterbalanced the interaction between justice and framing, such that for individuals with high self-efficacy/low trait anxiety, justice effects were larger in negative framing than in positive framing; those with the opposite disposition exhibited the opposite pattern. These effects were interpreted in terms of an attribution process as the information processing strategy. The aforementioned findings suggest that the justice and decision theories can be developed to account for the moderating effects of personality traits. Some limitations of this study and the direction of future research are also discussed. PMID:23469475

  6. Development of an indirect counterbalanced pendulum optical-lever thrust balance for micro- to millinewton thrust measurement

    NASA Astrophysics Data System (ADS)

    Grubii?, A. N.; Gabriel, S. B.

    2010-10-01

    This paper describes the design and testing of an indirect hanging pendulum thrust balance using a laser-optical-lever principle to provide micro- to millinewton thrust measurement for the development of electric propulsion systems. The design philosophy allows the selection of the total thrust range in order to maximize resolution through a counterbalanced pendulum principle, as well as passive magnetic damping in order to allow relatively rapid transient thrust measurement. The balance was designed for the purpose of hollow cathode microthruster characterization, but could be applied to other electric propulsion devices in the thrust range of micro- to millinewtons. An initial thrust characterization of the T5 hollow cathode is presented.

  7. Elevating your elevator talk

    Technology Transfer Automated Retrieval System (TEKTRAN)

    An important and often overlooked item that every early career researcher needs to do is compose an elevator talk. The elevator talk, named because the talk should not last longer than an average elevator ride (30 to 60 seconds), is an effective method to present your research and yourself in a clea...

  8. Implementation and integration of a counterbalanced CRT-based stereoscopic display for interactive viewpoint control in virtual environment applications

    NASA Technical Reports Server (NTRS)

    Mcdowall, I. E.; Bolas, M.; Pieper, S.; Fisher, S. S.; Humphries, J.

    1990-01-01

    The NASA-Ames Counterbalanced CRT-based Stereoscopic Viewer (CCSV), which is being used as a viewing device for biomechanical CAD environments, is uniquely suited for applications in which the user frequently moves between desk work and virtual environment viewing, or in which high resolution views of the virtual environment are required, or in which the viewing device must be shared among collaborators in a group setting. The CCSV hardware encompasses a dual-CRT-based stereoscopic viewer with wide-angle optics, a video electronics box, a dedicated microprocessor system monitoring joint angles in the linkage, and a host computer interpreting sensor values and running the application which renders the right and left views for reader CRTs.

  9. Counterbalanced refueling arm assembly

    SciTech Connect

    Fournier, P.J.E.; Reinker, J.F., Jr.

    1990-02-06

    This patent describes a counter balanced refueling arm. It comprises: a supporting platform, wheels supporting the platform, an outer caster assembly. The wheel, a first swivel joint mounted on the outboard caster assembly having a substantially vertical axis of rotation, an inlet and an outlet defined on the joint, a fuel supply conduit communicating with the joint inlet, a second swivel joint mounted on the platform having a substantially horizontal axis of rotation, an inlet and an outlet, a rigid conduit interconnecting the first joint outlet with the second joint inlet establishing communication between the first and second joint, a substantially rigid arm conduit having an axis, an inner end affixed to and communicating with the second joint outlet and an outer end. The arm conduit being pivoted about the second joint axis within a substantially vertical plane, a first elbow swivel coupling having an inlet connected to the arm conduit outer end, an outlet and an axis of rotation transverse to the arm conduit axis, a second elbow swivel coupling having an inlet connected to the first coupling outlet, an outlet and an axis of rotation transverse to aid first coupling axis, a third elbow swivel coupling having an inlet connected to the second coupling outlet, an outlet and an axis of rotation transverse to the coupling axis, and a nozzle connected to the third coupling outlet.

  10. Microbe-driven turnover offsets mineral-mediated storage of soil carbon under elevated CO2

    NASA Astrophysics Data System (ADS)

    Sulman, Benjamin N.; Phillips, Richard P.; Oishi, A. Christopher; Shevliakova, Elena; Pacala, Stephen W.

    2014-12-01

    The sensitivity of soil organic carbon (SOC) to changing environmental conditions represents a critical uncertainty in coupled carbon cycle-climate models. Much of this uncertainty arises from our limited understanding of the extent to which root-microbe interactions induce SOC losses (through accelerated decomposition or `priming') or indirectly promote SOC gains (via `protection' through interactions with mineral particles). We developed a new SOC model to examine priming and protection responses to rising atmospheric CO2. The model captured disparate SOC responses at two temperate free-air CO2 enrichment (FACE) experiments. We show that stabilization of `new' carbon in protected SOC pools may equal or exceed microbial priming of `old' SOC in ecosystems with readily decomposable litter and high clay content (for example, Oak Ridge). In contrast, carbon losses induced through priming dominate the net SOC response in ecosystems with more resistant litters and lower clay content (for example, Duke). The SOC model was fully integrated into a global terrestrial carbon cycle model to run global simulations of elevated CO2 effects. Although protected carbon provides an important constraint on priming effects, priming nonetheless reduced SOC storage in the majority of terrestrial areas, partially counterbalancing SOC gains from enhanced ecosystem productivity.

  11. Elevated CO2 Does Not Stimulate C4 Photosynthesis Directly, but Impacts Water Relations and Indirectly Enhances Carbon Gain during Drought Stress in Maize (Zea Mays) grown under free-air CO2 enrichment (FACE)

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The mechanism of [CO2] effects upon C4 plants has received considerable research interest but remains poorly understood. In 2002 and 2004, a rainfed-field experiment utilizing FACE technology was undertaken, in the U.S. Corn Belt, to determine the effects of elevated [CO2] on Zea mays. FACE allows ...

  12. (In)Consistencies in Responses to Sodium Bicarbonate Supplementation: A Randomised, Repeated Measures, Counterbalanced and Double-Blind Study

    PubMed Central

    Froio de Araujo Dias, Gabriela; da Eira Silva, Vinicius; de Salles Painelli, Vitor; Sale, Craig; Giannini Artioli, Guilherme; Gualano, Bruno; Saunders, Bryan

    2015-01-01

    Objectives Intervention studies do not account for high within-individual variation potentially compromising the magnitude of an effect. Repeat administration of a treatment allows quantification of individual responses and determination of the consistency of responses. We determined the consistency of metabolic and exercise responses following repeated administration of sodium bicarbonate (SB). Design and Methods 15 physically active males (age 25±4 y; body mass 76.0±7.3 kg; height 1.77±0.05 m) completed six cycling capacity tests at 110% of maximum power output (CCT110%) following ingestion of either 0.3 g∙kg-1BM of SB (4 trials) or placebo (PL, 2 trials). Blood pH, bicarbonate, base excess and lactate were determined at baseline, pre-exercise, post-exercise and 5-min post-exercise. Total work done (TWD) was recorded as the exercise outcome. Results SB supplementation increased blood pH, bicarbonate and base excess prior to every trial (all p ≤ 0.001); absolute changes in pH, bicarbonate and base excess from baseline to pre-exercise were similar in all SB trials (all p > 0.05). Blood lactate was elevated following exercise in all trials (p ≤ 0.001), and was higher in some, but not all, SB trials compared to PL. TWD was not significantly improved with SB vs. PL in any trial (SB1: +3.6%; SB2 +0.3%; SB3: +2.1%; SB4: +6.7%; all p > 0.05), although magnitude-based inferences suggested a 93% likely improvement in SB4. Individual analysis showed ten participants improved in at least one SB trial above the normal variation of the test although five improved in none. Conclusions The mechanism for improved exercise with SB was consistently in place prior to exercise, although this only resulted in a likely improvement in one trial. SB does not consistently improve high intensity cycling capacity, with results suggesting that caution should be taken when interpreting the results from single trials as to the efficacy of SB supplementation. Trial Registration ClinicalTrials.gov NCT02474628 PMID:26574755

  13. Monocular Elevation Deficiency - Double Elevator Palsy

    MedlinePLUS

    ... Eye Terms Conditions Frequently Asked Questions Español Condiciones Chinese Conditions Monocular Elevation Deficiency/ Double Elevator Palsy En Español Read in Chinese What is monocular elevation deficiency (Double Elevator Palsy)? ...

  14. Cyclic-AMP metabolism in synaptic growth, strength and precision: Neural and behavioral phenotype-specific counterbalancing effects between dnc PDE and rut AC mutations

    PubMed Central

    Ueda, Atsushi; Wu, Chun-Fang

    2012-01-01

    Two classic learning mutants in Drosophila, rutabaga (rut) and dunce (dnc), are defective in cAMP synthesis and degradation, respectively, exhibiting a variety of neuronal and behavioral defects. We ask how the opposing effects of these mutations on cAMP levels modify subsets of phenotypes, and whether any specific phenotypes could be ameliorated by biochemical counter balancing effects in dnc rut double mutants. Our study at larval neuromuscular junctions (NMJs) demonstrate that dnc mutations caused severe defects in nerve terminal morphology, characterized by unusually large synaptic boutons and aberrant innervation patterns. Interestingly, a counterbalancing effect led to rescue of the aberrant innervation patterns but the enlarged boutons in dnc rut double mutant remained as extreme as those in dnc. In contrast to dnc, rut mutations strongly affect synaptic transmission. Focal loose-patch recording data accumulated over 4 years suggest that synaptic currents in rut boutons were characterized by unusually large temporal dispersion and a seasonal variation in the amount of transmitter release, with diminished synaptic currents in summer months. Experiments with different rearing temperatures revealed that high temperature (2930 C) decreased synaptic transmission in rut, but did not alter dnc and WT. Importantly, the large temporal dispersion and abnormal temperature dependence of synaptic transmission, characteristic of rut, still persisted in dnc rut double mutants. To interpret these results in a proper perspective, we reviewed previously documented differential effects of dnc and rut mutations and their genetic interactions in double mutants on a variety of physiological and behavioral phenotypes. The cases of rescue in double mutants are associated with gradual developmental and maintenance processes whereas many behavioral and physiological manifestations on faster time scales could not be rescued. We discuss factors that could contribute to the effectiveness of counter balancing interactions between dnc and rut mutations for phenotypic rescue. PMID:22380612

  15. No evidence of dehydration with moderate daily coffee intake: a counterbalanced cross-over study in a free-living population.

    PubMed

    Killer, Sophie C; Blannin, Andrew K; Jeukendrup, Asker E

    2014-01-01

    It is often suggested that coffee causes dehydration and its consumption should be avoided or significantly reduced to maintain fluid balance. The aim of this study was to directly compare the effects of coffee consumption against water ingestion across a range of validated hydration assessment techniques. In a counterbalanced cross-over design, 50 male coffee drinkers (habitually consuming 3-6 cups per day) participated in two trials, each lasting three consecutive days. In addition to controlled physical activity, food and fluid intake, participants consumed either 4200 mL of coffee containing 4 mg/kg caffeine (C) or water (W). Total body water (TBW) was calculated pre- and post-trial via ingestion of Deuterium Oxide. Urinary and haematological hydration markers were recorded daily in addition to nude body mass measurement (BM). Plasma was analysed for caffeine to confirm compliance. There were no significant changes in TBW from beginning to end of either trial and no differences between trials (51.51.4 vs. 51.41.3 kg, for C and W, respectively). No differences were observed between trials across any haematological markers or in 24 h urine volume (2409660 vs. 2428669 mL, for C and W, respectively), USG, osmolality or creatinine. Mean urinary Na(+) excretion was higher in C than W (p?=?0.02). No significant differences in BM were found between conditions, although a small progressive daily fall was observed within both trials (0.40.5 kg; p<0.05). Our data show that there were no significant differences across a wide range of haematological and urinary markers of hydration status between trials. These data suggest that coffee, when consumed in moderation by caffeine habituated males provides similar hydrating qualities to water. PMID:24416202

  16. Preventing Weight Gain

    MedlinePLUS

    ... Weight Body Mass Index (BMI) About Adult BMI Adult BMI Calculator Metric Version  About Child & Teen BMI Measuring Children's Height and Weight Accurately At Home Child & Teen BMI Calculator Children's BMI Tool for Schools Finding a Balance Other Factors in Weight Gain Preventing Weight Gain ...

  17. Invention and Gain Analysis.

    ERIC Educational Resources Information Center

    Weber, Robert J.; Dixon, Stacey

    1989-01-01

    Gain analysis is applied to the invention of the sewing needle as well as different sewing implements and modes of sewing. The analysis includes a two-subject experiment. To validate the generality of gain heuristics and underlying switching processes, the invention of the assembly line is also analyzed. (TJH)

  18. Receiver Gain Modulation Circuit

    NASA Technical Reports Server (NTRS)

    Jones, Hollis; Racette, Paul; Walker, David; Gu, Dazhen

    2011-01-01

    A receiver gain modulation circuit (RGMC) was developed that modulates the power gain of the output of a radiometer receiver with a test signal. As the radiometer receiver switches between calibration noise references, the test signal is mixed with the calibrated noise and thus produces an ensemble set of measurements from which ensemble statistical analysis can be used to extract statistical information about the test signal. The RGMC is an enabling technology of the ensemble detector. As a key component for achieving ensemble detection and analysis, the RGMC has broad aeronautical and space applications. The RGMC can be used to test and develop new calibration algorithms, for example, to detect gain anomalies, and/or correct for slow drifts that affect climate-quality measurements over an accelerated time scale. A generalized approach to analyzing radiometer system designs yields a mathematical treatment of noise reference measurements in calibration algorithms. By treating the measurements from the different noise references as ensemble samples of the receiver state, i.e. receiver gain, a quantitative description of the non-stationary properties of the underlying receiver fluctuations can be derived. Excellent agreement has been obtained between model calculations and radiometric measurements. The mathematical formulation is equivalent to modulating the gain of a stable receiver with an externally generated signal and is the basis for ensemble detection and analysis (EDA). The concept of generating ensemble data sets using an ensemble detector is similar to the ensemble data sets generated as part of ensemble empirical mode decomposition (EEMD) with exception of a key distinguishing factor. EEMD adds noise to the signal under study whereas EDA mixes the signal with calibrated noise. It is mixing with calibrated noise that permits the measurement of temporal-functional variability of uncertainty in the underlying process. The RGMC permits the evaluation of EDA by modulating the receiver gain using an external signal. Without the RGMC, samples of calibrated references from radiometers form an ensemble data set of the natural occurring fluctuations within a receiver. By driving the gain of an otherwise stable receiver with an external signal, the conceptual framework and generalization of the mathematics of EDA can be tested. A series of measurements was conducted to evaluate and characterize the performance of the RGMC. Test signals stepped the RGMC across its dynamic range of performance using a radiometer that sampled four noise references; analysis indicates that the RGMC successfully modulated the receiver gain with an external signal. Calibration algorithms applied to four noise references demonstrate the RGMC produced ensemble data sets of the external signal.

  19. Gain in optical coatings

    NASA Astrophysics Data System (ADS)

    Macleod, Angus; Clark, Christopher

    2012-10-01

    The introduction of gain into an optical medium is most easily accomplished by reversing the sign of the extinction coefficient. The theoretical expression for reflectance at a simple boundary between a dielectric, lossless incident medium and a medium with a finite extinction coefficient, however, takes no account of the sign of the extinction coefficient In such an arrangement, therefore, can the presence of gain possibly result in an enhanced reflectance? Opinions in the literature differ but tend to find enhancement beyond the critical angle and none below. This study examines both cases and shows that all results are in fact correct but they are not necessarily stable and it is their stability, or lack of it, that leads to the different results.

  20. Amoco technique gains support

    SciTech Connect

    1995-10-01

    Amoco Corp.`s low-cost horizontal drilling technique and equipment are gaining acceptance in the oilpatch after five years of design and fine-tuning work. The system is purely mechanical, and it`s designed to operate with a workover rig instead of a drilling rig. It`s engineered to drill short-radius horizontal wells with lateral sup to 1,000 feet, so far.

  1. Helicopter high gain control

    NASA Technical Reports Server (NTRS)

    Cunningham, T. B.; Nunn, E. C.

    1979-01-01

    High gain control is explored through a design study of the CH-47B helicopter. The plans are designed to obtain the maximum bandwidth possible given the hardware constraints. Controls are designed with modal control theory to specific bandwidths and closed loop mode shapes. Comparisons are made to an earlier complementary filter approach. Bandwidth improvement by removal of limitations is explored in order to establish hardware and mechanization options. Improvements in the pitch axis control system and in the rate gyro sensor noise characteristics in all axes are discussed. The use of rotor state feedback is assessed.

  2. Tertiary gain and disability syndromes.

    PubMed

    Kwan, O; Ferrari, R; Friel, J

    2001-10-01

    Since the introduction of the concept of tertiary gain by Dansak in 1973, there has been little further publication or research on this topic. Yet, tertiary gain is often the subject of debate amongst physicians, therapists, insurers, the media, and even at times the general public. Much of the controversy of disability syndromes and the health and economic burden they present has focused on secondary gain and illness behaviour. The role of tertiary gain in illness behaviour is likely also relevant, and a model of tertiary gain is needed to begin further understanding the implications of this phenomenon for patients and those who treat them. This article introduces a phraseology for tertiary gain, and models the effects of tertiary gain on illness behaviour and the interactions of secondary and tertiary gain in the setting of disability syndromes. PMID:11601869

  3. USGS Elevation Monument

    USGS Multimedia Gallery

    USGS elevation monument for a level line run from Mojave, California to Keeler, California. The line ran through such places as 18-Mile Station, Dixie, Indan Wells, Little Lake, and Olancha. Elevations were based on Benecia datum....

  4. Acting to gain information

    NASA Technical Reports Server (NTRS)

    Rosenchein, Stanley J.; Burns, J. Brian; Chapman, David; Kaelbling, Leslie P.; Kahn, Philip; Nishihara, H. Keith; Turk, Matthew

    1993-01-01

    This report is concerned with agents that act to gain information. In previous work, we developed agent models combining qualitative modeling with real-time control. That work, however, focused primarily on actions that affect physical states of the environment. The current study extends that work by explicitly considering problems of active information-gathering and by exploring specialized aspects of information-gathering in computational perception, learning, and language. In our theoretical investigations, we analyzed agents into their perceptual and action components and identified these with elements of a state-machine model of control. The mathematical properties of each was developed in isolation and interactions were then studied. We considered the complexity dimension and the uncertainty dimension and related these to intelligent-agent design issues. We also explored active information gathering in visual processing. Working within the active vision paradigm, we developed a concept of 'minimal meaningful measurements' suitable for demand-driven vision. We then developed and tested an architecture for ongoing recognition and interpretation of visual information. In the area of information gathering through learning, we explored techniques for coping with combinatorial complexity. We also explored information gathering through explicit linguistic action by considering the nature of conversational rules, coordination, and situated communication behavior.

  5. Managing price, gaining profit.

    PubMed

    Marn, M V; Rosiello, R L

    1992-01-01

    The fastest and most effective way for a company to realize maximum profit is to get its pricing right. The right price can boost profit faster than increasing volume will; the wrong price can shrink it just as quickly. Yet many otherwise tough-minded managers miss out on significant profits because they shy away from pricing decisions for fear that they will alienate their customers. Worse, if management isn't controlling its pricing policies, there's a good chance that the company's clients are manipulating them to their own advantage. McKinsey & Company's Michael Marn and Robert Rosiello show managers how to gain control of the pricing puzzle and capture untapped profit potential by using two basic concepts: the pocket price waterfall and the pocket price band. The pocket price waterfall reveals how price erodes between a company's invoice figure and the actual amount paid by the customer--the transaction price. It tracks the volume purchase discounts, early payment bonuses, and frequent customer incentives that squeeze a company's profits. The pocket price band plots the range of pocket prices over which any given unit volume of a single product sells. Wide price bands are commonplace: some manufacturers' transaction prices for a given product range 60%; one fastener supplier's price band ranged up to 500%. Managers who study their pocket price waterfalls and bands can identify unnecessary discounting at the transaction level, low-performance accounts, and misplaced marketing efforts. The problems, once identified, are typically easy and inexpensive to remedy. PMID:10121318

  6. The Space Elevator

    NASA Astrophysics Data System (ADS)

    Laubscher, Bryan E.

    2005-09-01

    The Space Elevator is conceived to be a carbon nanotube ribbon stretching from an Earth station in the ocean on the equator to far beyond geosynchronous altitude. This elevator co-rotates with the Earth. Climbers ascend the ribbon using power beamed from Earth to launch spacecraft in orbit or to other worlds. The requirements of the ribbon material, challenges to the building of the space elevator, deployment and the promise of the space elevator are briefly discussed in this paper.

  7. National Elevation Dataset

    USGS Publications Warehouse

    U.S. Geological Survey

    1999-01-01

    The National Elevation Dataset (NED) is a new raster product assembled by the U.S. Geological Survey (USGS). The NED is designed to provide national elevation data in a seamless form with a consistent datum, elevation unit, and projection. Data corrections were made in the NED assembly process to minimize artifacts, permit edge matching, and fill sliver areas of missing data.

  8. 49. East elevation of elevated Mainline Structure (Section F5) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    49. East elevation of elevated Mainline Structure (Section F-5) - looking West - toward Washington Street near Marcella Street. Highland Park and the Water Tower are in the background. - Boston Elevated Railway, Elevated Mainline, Washington Street, Boston, Suffolk County, MA

  9. Smoking cessation and weight gain.

    PubMed

    Filozof, C; Fernndez Pinilla, M C; Fernndez-Cruz, A

    2004-05-01

    Cigarette smoking is the single most important preventable cause of death and illness. Smoking cessation is associated with substantial health benefits. Weight gain is cited as a primary reason for not trying to quit smoking. There is a great variability in the amount of weight gain but younger ages, lower socio-economic status and heavier smoking are predictors of higher weight gain. Weight change after smoking cessation appears to be influenced by underlying genetic factors. Besides, weight gain after smoking cessation is largely because of increased body fat and some studies suggest that it mostly occurs in the subcutaneous region of the body. The mechanism of weight gain includes increased energy intake, decreased resting metabolic rate, decreased physical activity and increased lipoprotein lipase activity. Although there is convincing evidence for the association between smoking cessation and weight gain, the molecular mechanisms underlying this relationship are not well understood. This review summarizes current information of the effects of nicotine on peptides involved in feeding behaviour. Smoking was shown to impair glucose tolerance and insulin sensitivity and cross-sectional studies have demonstrated that smokers are insulin-resistant and hyperinsulinaemic, as compared with non-smokers. Smoking cessation seems to improve insulin sensitivity in spite of the weight gain. Nicotine replacement - in particular nicotine gum - appears to be effective in delaying post-cessation weight gain. In a group of women who failed to quit smoking because of weight gain, a dietary intervention (intermittent very-low-calorie diet) plus nicotine gum showed to both increase success rate in terms of smoking cessation and prevent weight gain. On the other hand, body weight gain at the end of treatment was significantly lower in the patients receiving bupropion or bupropion plus nicotine patch, compared with placebo. Studies with new drugs available for the treatment of obesity - sibutramine and orlistat - are warranted. PMID:15086863

  10. Computer algorithm for coding gain

    NASA Technical Reports Server (NTRS)

    Dodd, E. E.

    1974-01-01

    Development of a computer algorithm for coding gain for use in an automated communications link design system. Using an empirical formula which defines coding gain as used in space communications engineering, an algorithm is constructed on the basis of available performance data for nonsystematic convolutional encoding with soft-decision (eight-level) Viterbi decoding.

  11. Outcomes of maternal weight gain.

    PubMed Central

    Viswanathan, Meera; Siega-Riz, Anna Maria; Moos, Merry K; Deierlein, Andrea; Mumford, Sunni; Knaack, Julie; Thieda, Patricia; Lux, Linda J; Lohr, Kathleen N

    2008-01-01

    OBJECTIVES The RTI International-University of North Carolina at Chapel Hill Evidence-based Practice Center (RTI-UNC EPC) systematically reviewed evidence on outcomes of gestational weight gain and their confounders and effect modifiers, outcomes of weight gain within or outside the 1990 Institute of Medicine (IOM) guidelines, risks and benefits of weight gain recommendations, and anthropometric measures of weight gain. DATA SOURCES We searched MEDLINE Cochrane Collaboration resources, Cumulative Index to Nursing & Allied Health Literature, and Embase. REVIEW METHODS We included studies published in English from 1990 through October 2007. We excluded studies with low sample size (based on study design: case series <100 subjects and cohorts <40 subjects). RESULTS Overall, strong evidence supported an association between gestational weight gains and the following outcomes: preterm birth, total birthweight, low birthweight (<2,500 g), macrosomia, large-for-gestational-age (LGA) infants, and small-for-gestational-age (SGA) infants; moderate evidence supported an association for cesarean delivery and intermediate-term weight retention (3 months to 3 years postpartum). The studies reviewed provided strong evidence for the independent association of pregravid weight status and outcomes, moderate evidence for age and parity, and weak evidence for race. Regarding outcomes of weight gain within or outside 1990 IOM guidelines, moderate to strong evidence suggests an association between weight gain below IOM recommendations and preterm birth, low birthweight, SGA birthweights, and failure to initiate breastfeeding, and strong evidence for the association between weight gain above IOM recommendations and high birthweight, macrosomia, and LGA birthweights. Moderate evidence supports an association between weight gain above IOM guidelines and cesarean delivery and postpartum weight retention in the short, intermediate, and long term. Included research is inadequate for objective assessments of the range of harms and benefits of providing all women, irrespective of age, race or ethnicity, or pregravid body mass index (BMI), with the same recommendation for weight gain in pregnancy. CONCLUSIONS Gestational weight gain is associated with some infant and maternal outcomes. One weight gain recommendation for all women is not supported by the evidence identified in this review. To understand fully the impact of gestational weight gain on short- and long-term outcomes for women and their offspring will require that researchers use consistent definitions of weight gain during pregnancy, better address confounders in their analyses, improve study designs and statistical models, and conduct studies with longer followup. PMID:18620471

  12. NATIONAL ELEVATION DATASET

    EPA Science Inventory

    The USGS National Elevation Dataset (NED) has been developed by merging the highest-resolution, best-quality elevation data available across the United States into a seamless raster format. NED is the result of the maturation of the USGS effort to provide 1:24,000-scale Digital ...

  13. NATIONAL ELEVATION DATASET HILLSHADE

    EPA Science Inventory

    The USGS National Elevation Dataset (NED) has been developed bymerging the highest-resolution, best-quality elevation data available across the United States into a seamless raster format. NED is the result of the maturation of the USGS effort to provide 1:24,000-scale Digital E...

  14. Mars elevation distribution

    NASA Technical Reports Server (NTRS)

    Wu, Sherman S. C.; Howington-Kraus, Annie E.; Ablin, Karyn K.

    1991-01-01

    A Digital Terrain Model (DTM) of Mars was derived with both Mercator and Sinusoidal Equal-Area projections from the global topographic map of Mars (scale 1:15 million, contour interval 1 km). Elevations on the map are referred to Mars' topographic datum that is defined by the gravity field at a 6.1-millibar pressure surface with respect to the center of mass of Mars. The DTM has a resolution at the equator of 1/59.226 degrees (exactly 1 km) per pixel. By using the DTM, the volumetric distribution of Mars topography above and below the datum has previously been calculated. Three types of elevation distributions of Mars' topography were calculated from the same DTM: (1) the frequency distribution of elevations at the pixel resolution; (2) average elevations in increments of 6 degrees in both longitude and latitude; and (3) average elevations in 36 separate blocks, each covering 30 degrees of latitude and 60 degrees of longitude.

  15. Mechanisms of the Rosetta high gain antenna

    NASA Astrophysics Data System (ADS)

    Pereira, Carlos

    2001-09-01

    This paper describes the antenna pointing mechanism (APM) and the hold down and release mechanism (HRM) used in the high gain antenna of the ROSETTA mission. The hold down and release mechanism consists of three units which compensate the tolerance mismatch between antenna and spacecraft through incorporation of potting rings. Given that the activation mode is pyrotechnic, release shock is a major concern and is minimised through integration of shock absorbers which allow stroking of the separation nuts. The antenna pointing mechanism is a dual drive (azimuth over elevation) unit which allows controlled rotation of the antenna. The drive units incorporate spring loaded end stops to prevent the antenna from hitting the spacecraft, and optical encoders which register the absolute position of the antenna. The pointing and the hold down mechanisms of the ROSETTA antenna are fully qualified and will withstand the high launch loads of the Ariane-5 and the environmental demands of deep space operation.

  16. [Elevated gastric lesions].

    PubMed

    de Careaga, B; Villagmez, G; Pabn, J; Caldern, O; Elo, D; Prez, J; Martnez, M; Patio, F; Ponce, R; Lora, J

    1986-01-01

    Elevated gastric lesions, represent an important group among gastric pathology. To establish its incidence in our experience, we studied the endoscopic reports of two important hospitals in La Paz city: Instituto de Gastroenterologa Boliviano Japons and Hospital Obrero No. 1. In order to make a good endoscopic diagnosis among different elevated lesions we use some parameters like: location, shape, size, diameter, surface of the lesion and surrounding mucosa and characteristics of the falls. 10.472 endoscopic reports were reviewed, 497 elevated gastric lesions were found, 475 corresponded to mucosal lesions (352 benign lesions and 123 malignant lesions), 11 to submucosal and 11 extragastric lesions. PMID:3661077

  17. Loaded sectioned space elevator

    NASA Astrophysics Data System (ADS)

    Sadov, Yu. A.; Nuralieva, A. B.

    2015-05-01

    New super strong materials discovered at the end of the 20th century have caused a surge of activity in work devoted to the space elevator (SE). A rather complete concept of the SE has been formulated. This concept, having many advantages, possesses, nevertheless, limited capabilities and insufficient reliability. In this paper we present a modified space elevator concept [1] that has higher reliability and extended capabilities. Such a construction is more complicated and its design is more expensive, so it can be realized only as a part of a large-scale space program. Inclusion of a space elevator in such a program will facilitate development of new technologies.

  18. Redundancy gain in semantic categorisation.

    PubMed

    Shepherdson, Peter; Miller, Jeff

    2014-05-01

    Redundancy gain refers to the performance enhancements often associated with the presentation of redundant versus single targets (for example, faster, more accurate, or more forceful responses). Though predominantly observed in relatively simple tasks (e.g., stimulus detection), there have been some efforts to investigate similar phenomena in tasks involving higher level processing. We conducted three experiments aimed at determining (a) whether a redundancy gain would be evident in a task unambiguously requiring higher level processing (the semantic categorisation of visually-presented lexical stimuli), and (b) if so, what accounts might be appropriate to explain such findings. We found that redundancy gains are observed in such tasks, and we conclude that both coactivation and race models can account for these gains. PMID:24508611

  19. Adaptive allocation of attentional gain

    PubMed Central

    Scolari, Miranda; Serences, John T.

    2009-01-01

    Humans are adept at distinguishing between stimuli that are very similar, an ability that is particularly crucial when the outcome is of serious consequence (e.g. for a surgeon or air traffic controller). Traditionally, selective attention was thought to facilitate perception by increasing the gain of sensory neurons tuned to the defining features of a behaviorally relevant object (e.g. color, orientation, etc.). In contrast, recent mathematical models counter-intuitively suggest that in many cases attentional gain should be applied to neurons that are tuned away from relevant features, especially when discriminating highly similar stimuli. Here we used psychophysical methods to critically evaluate these ideal observer models. The data demonstrate that attention enhances the gain of the most informative sensory neurons, even when these neurons are tuned away from the behaviorally relevant target feature. Moreover, the degree to which an individual adopted optimal attentional gain settings by the end of testing predicted success rates on a difficult visual discrimination task, as well as the amount of task improvement that occurred across repeated testing sessions (learning). Contrary to most traditional accounts, these observations suggest that the primary function of attentional gain is not simply to enhance the representation of target features, but to optimize performance on the current perceptual task. Additionally, individual differences in gain suggest that the operating characteristics of low-level attentional phenomena are not stable trait-like attributes and that variability in how attention is deployed may play an important role in determining perceptual abilities. PMID:19776279

  20. Northeast Elevation Mill #3, Northeast Elevation Mill #4 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Northeast Elevation - Mill #3, Northeast Elevation - Mill #4 (with Section of Courtyard), Southeast Elevation - Mill #4 North - Boott Cotton Mills, John Street at Merrimack River, Lowell, Middlesex County, MA

  1. Light: Isometric Casing with Lens, South Elevation, North Elevation, Top ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Light: Isometric Casing with Lens, South Elevation, North Elevation, Top Plan, Base Plan; Fresnel Lens: Isometric, Elevation, Plan - Fort Washington, Fort Washington Light, Northeast side of Potomac River at Fort Washington Park, Fort Washington, Prince George's County, MD

  2. East Elevation, East Portico Wall Elevation, Portico Column Details ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    East Elevation, East Portico Wall Elevation, Portico Column Details - National Home for Disabled Volunteer Soldiers, Mountain Branch, Administration Building, Lamont & Veterans Way, Johnson City, Washington County, TN

  3. Gain degradation and amplitude scintillation due to tropospheric turbulence

    NASA Technical Reports Server (NTRS)

    Theobold, D. M.; Hodge, D. B.

    1978-01-01

    It is shown that a simple physical model is adequate for the prediction of the long term statistics of both the reduced signal levels and increased peak-to-peak fluctuations. The model is based on conventional atmospheric turbulence theory and incorporates both amplitude and angle of arrival fluctuations. This model predicts the average variance of signals observed under clear air conditions at low elevation angles on earth-space paths at 2, 7.3, 20 and 30 GHz. Design curves based on this model for gain degradation, realizable gain, amplitude fluctuation as a function of antenna aperture size, frequency, and either terrestrial path length or earth-space path elevation angle are presented.

  4. Space Elevator: Stability

    NASA Astrophysics Data System (ADS)

    Perek, Lubos

    2008-04-01

    Many papers have been published on engineering and economic aspects of the Space Elevator. The Elevator, however, is a very special and unusual astronomical body. Its behavior in space is affected not only by the attraction of the Earth and by the "centrifugal force" but also by the attraction of the Sun and the Moon, by the detailed shape of the Earth, by the presence of space debris, etc. Not all of the minor effects have been adequately studied. The size of the Space Elevator and its lack of resistance against buckling or bending require a detailed study of its stability, both in its initial phase as a geostationary (GEO) satellite as well as in its operational phase as a "sling". Lunisolar perturbations and other minor forces may affect the stability in the initial phase and will cause oscillations in the operational phase. Station-keeping thrusters will have to be mounted at selected points along the cable in order to maintain stability. In addition, the thrusters will perform local maneuvers for avoiding collisions with passing space debris. The control system of thrusters has to be adaptive, reacting fast to actual situation and rectifying the attitude of the Elevator whenever necessary. A further advantage of the thrusters is a possibility to locate the Elevator at any longitude, possibly looking for a region with minimum traffic at GEO distance. Extensive numerical simulations will have to be performed in order to determine elements of the thrusters and their control system.

  5. Welfare Gains from Financial Liberalization

    PubMed Central

    Townsend, Robert M.; Ueda, Kenichi

    2010-01-01

    Financial liberalization has been a controversial issue, as empirical evidence for growth enhancing effects is mixed. Here, we find sizable welfare gains from liberalization (cost to repression), though the gain in economic growth is ambiguous. We take the view that financial liberalization is a government policy that alters the path of financial deepening, while financial deepening is endogenously chosen by agents given a policy and occurs in transition towards a distant steady state. This history-dependent view necessitates the use of simulation analysis based on a growth model. Our application is a specific episode: Thailand from 1976 to 1996. PMID:20806055

  6. Elevated BP after AKI.

    PubMed

    Hsu, Chi-Yuan; Hsu, Raymond K; Yang, Jingrong; Ordonez, Juan D; Zheng, Sijie; Go, Alan S

    2016-03-01

    The connection between AKI and BP elevation is unclear. We conducted a retrospective cohort study to evaluate whether AKI in the hospital is independently associated with BP elevation during the first 2 years after discharge among previously normotensive adults. We studied adult members of Kaiser Permanente Northern California, a large integrated health care delivery system, who were hospitalized between 2008 and 2011, had available preadmission serum creatinine and BP measures, and were not known to be hypertensive or have BP>140/90 mmHg. Among 43,611 eligible patients, 2451 experienced AKI defined using observed changes in serum creatinine concentration measured during hospitalization. Survivors of AKI were more likely than those without AKI to have elevated BP-defined as documented BP>140/90 mmHg measured during an ambulatory, nonemergency department visit-during follow-up (46.1% versus 41.2% at 730 days; P<0.001). This difference was evident within the first 180 days (30.6% versus 23.1%; P<0.001). In multivariable models, AKI was independently associated with a 22% (95% confidence interval, 12% to 33%) increase in the odds of developing elevated BP during follow-up, with higher adjusted odds with more severe AKI. Results were similar in sensitivity analyses when elevated BP was defined as having at least two BP readings of >140/90 mmHg or those with evidence of CKD were excluded. We conclude that AKI is an independent risk factor for subsequent development of elevated BP. Preventing AKI during a hospitalization may have clinical and public health benefits beyond the immediate hospitalization. PMID:26134154

  7. National Elevation Dataset

    USGS Publications Warehouse

    U.S. Geological Survey

    2002-01-01

    The National Elevation Dataset (NED) is a new raster product assembled by the U.S. Geological Survey. NED is designed to provide National elevation data in a seamless form with a consistent datum, elevation unit, and projection. Data corrections were made in the NED assembly process to minimize artifacts, perform edge matching, and fill sliver areas of missing data. NED has a resolution of one arc-second (approximately 30 meters) for the conterminous United States, Hawaii, Puerto Rico and the island territories and a resolution of two arc-seconds for Alaska. NED data sources have a variety of elevation units, horizontal datums, and map projections. In the NED assembly process the elevation values are converted to decimal meters as a consistent unit of measure, NAD83 is consistently used as horizontal datum, and all the data are recast in a geographic projection. Older DEM's produced by methods that are now obsolete have been filtered during the NED assembly process to minimize artifacts that are commonly found in data produced by these methods. Artifact removal greatly improves the quality of the slope, shaded-relief, and synthetic drainage information that can be derived from the elevation data. Figure 2 illustrates the results of this artifact removal filtering. NED processing also includes steps to adjust values where adjacent DEM's do not match well, and to fill sliver areas of missing data between DEM's. These processing steps ensure that NED has no void areas and artificial discontinuities have been minimized. The artifact removal filtering process does not eliminate all of the artifacts. In areas where the only available DEM is produced by older methods, then "striping" may still occur.

  8. The Gains from Vertical Scaling

    ERIC Educational Resources Information Center

    Briggs, Derek C.; Domingue, Ben

    2013-01-01

    It is often assumed that a vertical scale is necessary when value-added models depend upon the gain scores of students across two or more points in time. This article examines the conditions under which the scale transformations associated with the vertical scaling process would be expected to have a significant impact on normative interpretations

  9. 60. FORWARD AIRPLANE ELEVATOR PIT WITH ELEVATOR IN RAISED POSITION ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    60. FORWARD AIRPLANE ELEVATOR PIT WITH ELEVATOR IN RAISED POSITION AFT LOOKING FORWARD ON CENTERLINE SHOWING ELEVATOR GUIDES, WIREWAYS, SHEAVES, HYDRAULIC OIL TANKS AND ELEVATOR LANDING PADS. - U.S.S. HORNET, Puget Sound Naval Shipyard, Sinclair Inlet, Bremerton, Kitsap County, WA

  10. Dynamics of a divisive gain control in human vision.

    PubMed

    Wilson, H R; Kim, J

    1998-09-01

    Evidence for a divisive contrast gain control in human vision was obtained using a contrast version of the probe-on-flash technique that has been employed in the light adaptation literature. Thresholds were measured for a briefly flashed (30 ms), vertical test pattern superimposed on a cosine mask as a function of time after mask onset (SOA). Threshold elevations declined monotonically for SOAs up to 150 ms. and exhibited an exponential time course with an average time constant of 51 ms. Increment thresholds for the test as a function of mask contrast provide direct evidence that these effects are due to operation of a divisive gain control within the first 150 ms after stimulus onset. Experiments to measure the spatial spread of this gain control show it to be localized to a region of no more than 45 arc min radius. PMID:9775322

  11. Randoms and TOF gain revisited

    NASA Astrophysics Data System (ADS)

    Eriksson, Lars; Conti, Maurizio

    2015-02-01

    Time-of-flight (TOF) positron emission tomography (PET) typically reduces the variance in the images by a factor that is proportional to the size of the object to be scanned, and inversely proportional to the time resolution of the PET scanner. Attempts to better characterize this relationship and understand its limits have been published, showing that such gain also increases with random fraction. In this paper, new experimental and simulated data are analyzed and old results are incorporated in the study. The proportionality of TOF gain with time resolution is confirmed, the proportionality constant is measured, the effect of the randoms is validated, and the limit of the model for small objects is investigated.

  12. Redundancy gain for semantic features.

    PubMed

    Fiedler, Anja; Schrter, Hannes; Ulrich, Rolf

    2013-06-01

    In a go/no-go experiment, semantic redundancy gain was assessed for responses to single written words. Specifically, we asked participants to respond only to words whose meaning matched at least one semantic target feature-that is, the target category (e.g., animal), the target color (e.g., gray), or both. On redundant-target trials, the word (e.g., elephant) matched both semantic target features (i.e., gray and animal). On single-target trials, the word (e.g., beaver) matched one target feature (i.e., animal) and a nontarget feature (i.e., brown). We observed shorter reaction times in the redundant-target condition than in the faster single-target condition. Hence, the present study provides the first evidence that redundancy gain is not limited to responses to redundant proximal stimulus features but can also be observed for responses to semantic feature information. PMID:23250760

  13. Photomultiplier tube gain regulating system

    DOEpatents

    Johnson, Wayne F.

    1976-01-01

    This invention relates to an improved system for regulating the gain of a photomultiplier tube, and was designed for use with the photomultiplier tubes of a GeMSAEC fast analyzers. It has the following advantages over the prior system: noise is virtually eliminated; sample analysis can begin after 3 to 4 revolutions of the rotor; fluorescent and light scattering solutions can be used as a reference; and the reference solution can be in any cuvette on the rotor.

  14. Elevated temperature crack growth

    NASA Technical Reports Server (NTRS)

    Yau, J. F.; Malik, S. N.; Kim, K. S.; Vanstone, R. H.; Laflen, J. H.

    1985-01-01

    The objective of the Elevated Temperature Crack Growth Project is to evaluate proposed nonlinear fracture mechanics methods for application to combustor liners of aircraft gas turbine engines. During the first year of this program, proposed path-independent (P-I) integrals were reviewed for such applications. Several P-I integrals were implemented into a finite-element postprocessor which was developed and verified as part of the work. Alloy 718 was selected as the analog material for use in the forthcoming experimental work. A buttonhead, single-edge notch specimen was designed and verified for use in elevated-temperature strain control testing with significant inelastic strains. A crack mouth opening displacement measurement device was developed for further use.

  15. Elevated temperature reference spectra

    SciTech Connect

    Brown, D.; Phillips, B.; Tussey, L.

    1997-12-31

    A compilation of infrared spectra at elevated temperatures is required for the accurate quantification of gas concentrations for Fourier transform infrared (FTIR) extractive sampling of stack gases and FTIR in-situ process monitoring. Analysis of high temperature gases utilizing ambient temperature reference spectra can result in significant quantification errors. The US Air Force`s Arnold Engineering Development Center (AEDC) is currently assisting the EPA in measuring reference spectra and making existing and new data available to the public through two ongoing efforts. One of these efforts is the measurement of elevated temperature infrared reference spectra of the low vapor pressure hazardous air pollutants (HAP) compounds, as well as spectral interfering compounds. The equipment and procedures used for the elevated temperature reference spectra measurements is described as well as some of the challenges encountered in these measurements. Examples of the reference spectra are also presented. To make the reference spectra developed by AEDC and other EPA programs easily accessible, AEDC has also been tasked to maintain a site on the World Wide Web containing reference spectra, reports, and software tools of interest to the optical sensing community. This web site has seen increased use during the three years that it has been in existence with users from academia, commercial, and government, both domestic and foreign. The site has undergone several improvements since inception and actively solicits inputs for further improvements from its users. A description of this web site and recent improvements and additions is given in this paper.

  16. Stochastic Gain in Population Dynamics

    NASA Astrophysics Data System (ADS)

    Traulsen, Arne; Rhl, Torsten; Schuster, Heinz Georg

    2004-07-01

    We introduce an extension of the usual replicator dynamics to adaptive learning rates. We show that a population with a dynamic learning rate can gain an increased average payoff in transient phases and can also exploit external noise, leading the system away from the Nash equilibrium, in a resonancelike fashion. The payoff versus noise curve resembles the signal to noise ratio curve in stochastic resonance. Seen in this broad context, we introduce another mechanism that exploits fluctuations in order to improve properties of the system. Such a mechanism could be of particular interest in economic systems.

  17. Commutated automatic gain control system

    NASA Technical Reports Server (NTRS)

    Yost, S. R.

    1982-01-01

    A commutated automatic gain control (AGC) system was designed and built for a prototype Loran C receiver. The receiver uses a microcomputer to control a memory aided phase-locked loop (MAPLL). The microcomputer also controls the input/output, latitude/longitude conversion, and the recently added AGC system. The circuit designed for the AGC is described, and bench and flight test results are presented. The AGC circuit described actually samples starting at a point 40 microseconds after a zero crossing determined by the software lock pulse ultimately generated by a 30 microsecond delay and add network in the receiver front end envelope detector.

  18. Refrigeration Plant, North Elevation, Second Floor Plan, East Elevation, Ground ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Refrigeration Plant, North Elevation, Second Floor Plan, East Elevation, Ground Floor Plan, Section A-A - Kennecott Copper Corporation, On Copper River & Northwestern Railroad, Kennicott, Valdez-Cordova Census Area, AK

  19. View southeast, showing front elevation, side (west) elevation and ell. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View southeast, showing front elevation, side (west) elevation and ell. Outbuildings and field stretching to west and south - Conner Homestead, Epping Road (State Route 101), Exeter, Rockingham County, NH

  20. first floor plan, north elevation, east elevation, building section, door ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    first floor plan, north elevation, east elevation, building section, door details, window details, crown molding and location map - Cedar Pass Lodge, Cabin 9, 20681 South Dakota Highway 240, Interior, Jackson County, SD

  1. first floor plan, east elevation, north elevation, building section, paneling ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    first floor plan, east elevation, north elevation, building section, paneling details, crown molding and location map - Cedar Pass Lodge, Cabin 1-2, 20681 South Dakota Highway 240, Interior, Jackson County, SD

  2. first floor plan, west elevation, north elevation, building section, door ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    first floor plan, west elevation, north elevation, building section, door details, window details, paneling details, crown molding and location map - Cedar Pass Lodge, Cabin 14-16, 20681 South Dakota Highway 240, Interior, Jackson County, SD

  3. first floor plan, building section, west elevation, south elevation, baseboard ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    first floor plan, building section, west elevation, south elevation, baseboard profile, crown molding profile, window and door details - Cedar Pass Lodge, Cabin 22, 20681 South Dakota Highway 240, Interior, Jackson County, SD

  4. 49. EAST ELEVATION OF ASSEMBLING BUILDING #2 AND SOUTH ELEVATION ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    49. EAST ELEVATION OF ASSEMBLING BUILDING #2 AND SOUTH ELEVATION OF BODY BUILDING, 1980 (MMI) - Dodge Brothers Motor Car Company Plant, Between Joseph Campau & Conant Avenues, Hamtramck, Wayne County, MI

  5. VIEW SOUTHWEST, EAST GABLE ELEVATIONS AND NORTH ELEVATIONS OF ENGINE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW SOUTHWEST, EAST GABLE ELEVATIONS AND NORTH ELEVATIONS OF ENGINE HOUSE IN FOREGROUND AND ECCENTRIC HOUSE IN REAR NOTE ROD LINES IN FOREGROUND RIGHT. - Golden Oil Company, Lot 410 Lease, Sheffield Field, Donaldson, Warren County, PA

  6. 43. ELEVATOR HEADHOUSE INTERIOR: Interior view towards southeast of elevator ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    43. ELEVATOR HEAD-HOUSE INTERIOR: Interior view towards southeast of elevator head-house at the Washington and Mason Street powerhouse. - San Francisco Cable Railway, Washington & Mason Streets, San Francisco, San Francisco County, CA

  7. 3. A general elevation view looking west highlights the Elevator ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. A general elevation view looking west highlights the Elevator and Silo Complex C, commonly known as the 'Landmark' (1940). - Quaker Oats Cereal Factory, Southeast corner of Broadway & Mill Streets, Akron, Summit County, OH

  8. 44. VIEW OF ELEVATOR MOTOR LOCATED ABOVE TOP OF ELEVATOR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    44. VIEW OF ELEVATOR MOTOR LOCATED ABOVE TOP OF ELEVATOR NEAR WEST WALL OF MST STATION 111 ANTEROOM - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 West, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

  9. A gain-coefficient switched Alexandrite laser

    NASA Astrophysics Data System (ADS)

    Lee, Chris J.; van der Slot, Peter J. M.; Boller, Klaus-J.

    2013-01-01

    We report on a gain-coefficient switched Alexandrite laser. An electro-optic modulator is used to switch between high and low gain states by making use of the polarization dependent gain of Alexandrite. In gain-coefficient switched mode, the laser produces 85 ns pulses with a pulse energy of 240 mJ at a repetition rate of 5 Hz.

  10. Scalar gain interpretation of large order filters

    NASA Technical Reports Server (NTRS)

    Mason, Paul A. C.; Mook, D. Joseph

    1993-01-01

    A technique is developed which demonstrates how to interpret a large fully-populated filter gain matrix as a set of scalar gains. The inverse problem is also solved, namely, how to develop a large-order filter gain matrix from a specified set of scalar gains. Examples are given to illustrate the method.

  11. 3. Occident Terminal Elevator. Reinforced concrete. First total "electric" elevator ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Occident Terminal Elevator. Reinforced concrete. First total "electric" elevator at Duluth. (Powered by electrical substation instead of steam generator). - Occident Terminal Elevator & Storage Annex, South side of second slip, north from outer end of Rice's Point, east of Garfield Avenue, Duluth, St. Louis County, MN

  12. Elevations and Floor Plan of Shed No. 1, Elevations and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Elevations and Floor Plan of Shed No. 1, Elevations and Floor Plan of Work Shed, Elevations and Floor Plan of Garage - Roberts-Dolezal Farmstead, 75 miles northeast of the intersection of CR27 and FM 1722, Garrett, Ellis County, TX

  13. Redundancy gains in retinotopic cortex

    PubMed Central

    Jiang, Yuhong V.; Kanwisher, Nancy

    2013-01-01

    It is widely claimed that interactions among simultaneously presented visual stimuli are suppressive and that these interactions primarily occur when stimuli fall within the same receptive field (Desimone and Duncan 1995). Here, we show evidence for a novel form of interaction between simultaneously presented but distant stimuli that does not fit either pattern. To examine interactions between simultaneously presented stimuli, we measure the response to a single stimulus as a function of whether or not other stimuli are also presented simultaneously, and we further ask how the response to a given stimulus is affected by whether the simultaneously present stimuli are identical or different from each other. Our method reveals a new phenomenon of redundancy gain: the visual response to a stimulus is higher when accompanied by identical stimuli than when that stimulus is presented alone, even though the stimuli are displayed in separate visual quadrants. This pattern is observed throughout the visual hierarchy, including V1 and V2, and we show that it is distinct from the well-known simultaneous suppression effect (Kastner et al. 1998). We propose that the redundancy gain in early retinotopic cortex results from feedback from higher visual areas and may underlie perceptual averaging and other ensemble coding phenomena observed behaviorally. PMID:23904496

  14. Gain dynamics of semiconductor lasers

    NASA Astrophysics Data System (ADS)

    Hofmann, Martin R.

    1998-07-01

    The gain spectra and the dynamics of semiconductor lasers are investigated on timescales from continuous wave down to the 100 fs regime. First, we measure continuous wave gain spectra over a wide spectral range with a transmission experiment using the ultrabroad spectrum of a 10 fs Ti:sapphire laser. The agreement between our experimental results and a parameter-free microscopic theory is excellent, only if carrier scattering and polarization are treated correctly. Accordingly, carrier thermalization and material polarization dynamics have to be considered in order to achieve a fundamental understanding of the dynamics of semiconductor lasers. The ultrafast carrier and polarization dynamics are experimentally investigated by femtosecond heterodyne pump-probe and four-wave-mixing experiments. Finally, we study the influence of carrier thermalization on the emission dynamics of a vertical-cavity surface-emitting laser (VCSEL). The VCSEL is optically pumped with femtosecond pulses from a Ti:sapphire laser and the temporal evolution of its emission is investigated as a function of the initial excess energy of the photoexcited carriers. The dynamics become slower for larger excess energies since carrier cooling is slower. The fastest response is obtained for resonant pumping.

  15. Detecting Elevated Cholesterol Levels

    PubMed Central

    Reimer, H.L.; Elford, R.W.; Shumak, S.

    1991-01-01

    The Reflotron dry chemistry reflectance photometer was studied as a case-finding method in physicians' offices. A total of 713 adult patients had their risk factor profiles determined along with fingerprick blood cholesterol measurements. Blood cholesterol levels were classified into three categories, (<5.2 mmol/L), 51%; borderline high (5.2 to 6.1 mmol/L), 28%; and high (?6.2 mmol/L), 21%. The physicians' predictions from clinical risk factor profiles of which patients had elevated serum cholesterol levels were inaccurate. PMID:21229051

  16. Digital Elevation Models

    USGS Publications Warehouse

    U.S. Geological Survey

    1993-01-01

    The Earth Science Information Center (ESIC) distributes digital cartographic/geographic data files produced by the U.S. Geological Survey (USGS) as part of the National Mapping Program. Digital cartographic data files may be grouped into four basic types. The first of these, called a Digital Line Graph (DLG), is the line map information in digital form. These data files include information on base data categories, such as transportation, hypsography, hydrography, and boundaries. The second type, called a Digital Elevation Model (DEM), consists of a sampled array of elevations for a number of ground positions at regularly spaced intervals. The third type is Land Use and Land Cover digital data which provides information on nine major classes of land use such as urban, agricultural, or forest as well as associated map data such as political units and Federal land ownership. The fourth type, the Geographic Names Information System, provides primary information for all known places, features, and areas in the United States identified by a proper name.

  17. Elevated temperature biaxial fatigue

    NASA Technical Reports Server (NTRS)

    Jordan, E. H.

    1984-01-01

    A three year experimental program for studying elevated temperature biaxial fatigue of a nickel based alloy Hastelloy-X has been completed. A new high temperature fatigue test facility with unique capabilities has been developed. Effort was directed toward understanding multiaxial fatigue and correlating the experimental data to the existing theories of fatigue failure. The difficult task of predicting fatigue lives for non-proportional loading was used as an ultimate test for various life prediction methods being considered. The primary means of reaching improved undertanding were through several critical non-proportional loading experiments. It was discovered that the cracking mode switched from primarily cracking on the maximum shear planes at room temperature to cracking on the maximum normal strain planes at 649 C.

  18. Elevated temperature crack growth

    NASA Technical Reports Server (NTRS)

    Kim, K. S.; Vanstone, R. H.

    1992-01-01

    The purpose of this program was to extend the work performed in the base program (CR 182247) into the regime of time-dependent crack growth under isothermal and thermal mechanical fatigue (TMF) loading, where creep deformation also influences the crack growth behavior. The investigation was performed in a two-year, six-task, combined experimental and analytical program. The path-independent integrals for application to time-dependent crack growth were critically reviewed. The crack growth was simulated using a finite element method. The path-independent integrals were computed from the results of finite-element analyses. The ability of these integrals to correlate experimental crack growth data were evaluated under various loading and temperature conditions. The results indicate that some of these integrals are viable parameters for crack growth prediction at elevated temperatures.

  19. Antibiotics Might Cause Weight Gain in Kids

    MedlinePLUS

    ... nlm.nih.gov/medlineplus/news/fullstory_155294.html Antibiotics Might Cause Weight Gain in Kids Study finds ... 2015 THURSDAY, Oct. 22, 2015 (HealthDay News) -- Repeated antibiotic use is linked to greater weight gains in ...

  20. Elevated CO2 alters root N uptake and C turnover in Larrea tridentata L

    Technology Transfer Automated Retrieval System (TEKTRAN)

    To examine the impact of elevated CO2 on root N uptake, soil N availability and the feedbacks between them, we quantified the effects of elevated CO2 and N additions on root N uptake and leaf C gain in Larrea tridentata seedlings grown in reconstituted Mojave Desert soils. After six months of growt...

  1. Severely elevated transaminases in an adolescent male with anorexia nervosa.

    PubMed

    Smith, Ryan W; Korenblum, Chana; Thacker, Kunal; Bonifacio, Herbert Joey; Gonska, Tanja; Katzman, Debra K

    2013-11-01

    Anorexia nervosa (AN) is a serious disorder that is associated with numerous medical complications and affects both females and males. Severely elevated transaminases have been reported in adult and younger females. We report the first case of elevated transaminases in an adolescent male with AN. The pathophysiologic mechanism of severely elevated serum transaminases observed in malnourished adolescent males with AN is complex and appears to be multifactorial. We present the first case of an adolescent male with AN who developed severely elevated serum transaminases that normalized with improved nutrition and weight gain. Liver injury in patients with AN is a complex medical complication that appears to be multifactorial in origin. In this case, starvation-induced autophagy in the human liver was considered one of the most likely mechanisms to explain hepatocytic injury in this patient. PMID:23881604

  2. Forward ramp & low gain antenna

    NASA Technical Reports Server (NTRS)

    1997-01-01

    Mars Pathfinder's forward rover ramp can be seen successfully unfurled in this color image, taken by the Imager for Mars Pathfinder (IMP) on Sol 3. This ramp was not used for the deployment of the microrover Sojourner, which occurred at the end of Sol 2. When this image was taken, Sojourner was still latched to one of the lander's petals, waiting for the command sequence that would execute its descent off of the lander's petal. The image helped Pathfinder scientists determine whether to deploy the rover using the forward or backward ramps and the nature of the first rover traverse. The metallic object at the lower part of the image is the lander's low-gain antenna. The square at the end of the ramp is one of the spacecraft's magnetic targets. Dust that accumulates on the magnetic targets will later be examined by Sojourner's Alpha Proton X-Ray Spectrometer instrument for chemical analysis. At center, a lander petal is visible.

    spacecraft with highly focused science goals. The Jet Propulsion Laboratory, Pasadena, CA, developed and manages the Mars Pathfinder mission for NASA's Office of Space Science, Washington, D.C. JPL is an operating division of the California Institute of Technology (Caltech). The Imager for Mars Pathfinder (IMP) was developed by the University of Arizona Lunar and Planetary Laboratory under contract to JPL. Peter Smith is the Principal Investigator.

  3. Nicotine Replacement: Effects on Postcessation Weight Gain.

    ERIC Educational Resources Information Center

    Gross, Janet; And Others

    1989-01-01

    Examined nicotine replacement effects on postcessation weight gain in smoking cessation volunteers. Randomly assigned abstinent subjects to active nicotine or placebo gum conditions for 10 weeks. Analyses revealed strong evidence for gum effect on weight gain, with active gum users gaining mean total of 3.8 pounds compared with 7.8 pounds for…

  4. STADAN antenna gain calibration using radio stars

    NASA Technical Reports Server (NTRS)

    Taylor, R. E.

    1972-01-01

    An antenna gain measurement method was developed which utilizes a signal emitted from a radio star to determine absolute antenna gain at 136 MHz and 400 MHz for antennas in the STADAN network. An error analysis of the radio star method shows that the overall standard deviation uncertainty in antenna gain is + or - 0.6 db (1 sigma).

  5. Nicotine Replacement: Effects on Postcessation Weight Gain.

    ERIC Educational Resources Information Center

    Gross, Janet; And Others

    1989-01-01

    Examined nicotine replacement effects on postcessation weight gain in smoking cessation volunteers. Randomly assigned abstinent subjects to active nicotine or placebo gum conditions for 10 weeks. Analyses revealed strong evidence for gum effect on weight gain, with active gum users gaining mean total of 3.8 pounds compared with 7.8 pounds for

  6. Dynamics of Elevated Vortices.

    NASA Astrophysics Data System (ADS)

    Shapiro, Alan; Markowski, Paul

    1999-05-01

    Theoretical hydrodynamic models for the behavior of vortices with axially varying rotation rates are presented. The flows are inviscid, axisymmetric, and incompressible. Two flow classes are considered: (i) radially unbounded solid body-type vortices and (ii) vortex cores of finite radius embedded within radially decaying vortex profiles.For radially unbounded solid body-type vortices with axially varying rotation rates, the von Kármán-Bödewadt similarity principle is applicable and leads to exact nonlinear solutions of the Euler equations. A vortex overlying nonrotating fluid, a vortex overlying a vortex of different strength, and more generally, a vortex with N horizontal layers of different rotation rate are considered. These vortices cannot exist in a steady state because continuity of pressure across the horizontal interface between the vortex layers demands that a secondary (meridional) circulation be generated. These similarity solutions are characterized by radial and azimuthal velocity fields that increase with radius and a vertical velocity field that is independent of radius. These solutions describe nonlinear interactions between the vortex circulations and the vortex-induced secondary circulations, and may play a role in the dynamics of the interior regions of broad mesoscale vortices. Decaying, amplifying, and oscillatory solutions are found for different vertical boundary conditions and axial distributions of vorticity. The oscillatory solutions are characterized by pulsations of vortex strength in lower and upper levels associated with periodic reversals in the sense of the secondary circulation. These solutions provide simple illustrations of the `vortex valve effect,' sometimes used to explain cyclic changes in updraft and rotation strength in tornadic storms.A linear analysis of the Euler equations is used to describe the short-time behavior of an elevated vortex of finite radius embedded within a radially decaying vortex profile (i.e., elevated Rankine-type vortices). The linear solution describes the formation of a central updraft (as in the similarity solution) and an annular downdraft ringing the periphery of the vortex core (not accounted for in the similarity solution). Downdraft strength is sensitive to both the vortex core aspect ratio and outer vortex decay rate, being stronger and narrower for broader vortices and larger decay rates. It is hypothesized that this dynamically induced downdraft may facilitate the transport of mesocyclone vorticity down to low levels in supercell thunderstorms.

  7. Elevated temperature biaxial fatigue

    NASA Technical Reports Server (NTRS)

    Jordan, E. H.

    1985-01-01

    A 3 year experimental program for studying elevated temperature biaxial fatigue of a nickel based alloy Hastelloy-X has been completed. A new high temperature fatigue test facility with unique capabilities has been developed. Effort was directed toward understanding multiaxial fatigue and correlating the experimental data to the existing theories of fatigue failure. The difficult task of predicting fatigue lives for nonproportional loading was used as an ultimate test for various life prediction methods being considered. The primary means of reaching improved understanding were through several critical nonproportional loading experiments. The direction of cracking observed on failed specimens was also recorded and used to guide the development of the theory. Cyclic deformation responses were permanently recorded digitally during each test. It was discovered that the cracking mode switched from primarily cracking on the maximum shear planes at room temperature to cracking on the maximum normal strain planes at 649 C. In contrast to some other metals, loading path in nonproportional loading had little effect on fatigue lives. Strain rate had a small effect on fatigue lives at 649 C. Of the various correlating parameters the modified plastic work and octahedral shear stress were the most successful.

  8. Weight gain attitudes among pregnant adolescents.

    PubMed

    Stevens-Simon, C; Nakashima, I; Andrews, D

    1993-07-01

    Maternal weight gain is the most important, manageable determinant of infant birth weight among adolescents. Negative attitudes toward weight gain may adversely affect maternal weight gain. We hypothesized that (a) negative attitudes toward pregnancy weight gain are more common among younger pregnant adolescents, and (b) negative attitudes toward pregnancy weight gain adversely affect adolescent maternal weight gain. The study subjects, 99, radially diverse, pregnant 13 through 18 year olds, completed the 18-item, Likert-format, Pregnancy and Weight Gain Attitude Scale. Responses to the questionnaire indicated that most (83.8%) of the adolescents we interviewed had a positive attitude toward pregnancy weight gain when they entered prenatal care. Univariate analyses revealed that attitudes toward weight gain were unrelated to the respondents' ages but inversely related to their prepregnant weights (-0.16; p = 0.06) and the severity of their symptoms of depression (r = -0.26; p = 0.004). Attitudes toward weight gain were also directly related to their family support (r = 0.17; p = 0.06). Weight gain was significantly related to 4 of the 18 scale items but not to the total attitude scale score. We conclude that (a) the developmental task of formulating a positive body image does not foster more negative attitudes toward pregnancy weight gain among younger adolescents; (b) negative weight gain attitudes are most common among heavier adolescents, depressed adolescents, and adolescents who do not perceive their families as supportive; and (c) negative weight gain attitudes could adversely affect pregnancy weight gain. PMID:8399248

  9. Weight gain associated with antipsychotic drugs.

    PubMed

    Ganguli, R

    1999-01-01

    Weight gain has been reported with nearly every antipsychotic drug on the market (molindone is an exception). Weight gain occurs no matter what the patient's age, sex, or race and is seen with both oral and depot drug formulations. Numerous studies have found that patients gain weight when treated with a conventional antipsychotic, such as chlorpromazine, fluphenazine, and haloperidol. The newer, novel antipsychotics offer advantages over conventional antipsychotics, especially a relative lack of extrapyramidal symptoms, but some still have the disadvantage of causing weight gain. Clozapine and olanzapine in particular appear to cause substantial weight gain, much more so than do most conventional neuroleptics and novel agents such as risperidone. Given the risks to health and treatment compliance associated with weight gain and obesity, clinicians should monitor weight during the course of antipsychotic therapy and consider switching agents if excessive weight gain occurs. PMID:10548138

  10. Reward Region Responsivity Predicts Future Weight Gain and Moderating Effects of the TaqIA Allele

    PubMed Central

    Burger, Kyle S.; Yokum, Sonja

    2015-01-01

    Because no large prospective study has investigated neural vulnerability factors that predict future weight gain, we tested whether neural response to receipt and anticipated receipt of palatable food and monetary reward predicted body fat gain over a 3-year follow-up in healthy-weight adolescent humans and whether the TaqIA polymorphism moderates these relations. A total of 153 adolescents completed fMRI paradigms assessing response to these events; body fat was assessed annually over follow-up. Elevated orbitofrontal cortex response to cues signaling impending milkshake receipt predicted future body fat gain (r = 0.32), which is a novel finding that provides support for the incentive sensitization theory of obesity. Neural response to receipt and anticipated receipt of monetary reward did not predict body fat gain, which has not been tested previously. Replicating an earlier finding (Stice et al., 2008a), elevated caudate response to milkshake receipt predicted body fat gain for adolescents with a genetic propensity for greater dopamine signaling by virtue of possessing the TaqIA A2/A2 allele, but lower caudate response predicted body fat gain for adolescents with a genetic propensity for less dopamine signaling by virtue of possessing a TaqIA A1 allele, though this interaction was only marginal [p-value <0.05 corrected using voxel-level familywise error rate (pFWE) = 0.06]. Parental obesity, which correlated with TaqIA allele status (odds ratio = 2.7), similarly moderated the relation of caudate response to milkshake receipt to future body fat gain, which is another novel finding. The former interaction implies that too much or too little dopamine signaling and reward region responsivity increases risk for overeating, suggesting qualitatively distinct reward surfeit and reward deficit pathways to obesity. SIGNIFICANCE STATEMENT Because no large prospective study has investigated neural vulnerability factors that predict future weight gain we tested whether neural response to receipt and anticipated receipt of palatable food and monetary reward predicted body fat gain over 3-year follow-up in healthy-weight adolescent humans and whether the TaqIA polymorphism moderates these relations. Elevated reward activation in response to food cues predicted future body fat gain. Elevated reward response to food receipt predicted body fat gain for adolescents with a TaqIA A2/A2 allele and lower reward response predicted body fat gain for those with a TaqIA A1 allele. Results imply that too much or too little dopamine signaling and reward region responsivity increases risk for overeating. PMID:26180206

  11. 38. Second Floor Plan, North Elevation, South Elevation and Details. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    38. Second Floor Plan, North Elevation, South Elevation and Details. Addition to Bacteriology Laboratory at Letterman General Hospital, San Francisco, Cal. January 1916. BUILDING 1006. - Presidio of San Francisco, Letterman General Hospital, Building No. 27, Letterman Hospital Complex, Edie Road, San Francisco, San Francisco County, CA

  12. 35. Coal Fuel Elevator (diagonal in center), Fuel Elevator (left), ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    35. Coal Fuel Elevator (diagonal in center), Fuel Elevator (left), Fuel Storage Bins (center), and Power Plant (far center), and Retail Coal Storage Bins (right) Photograph taken by George Harven - Huber Coal Breaker, 101 South Main Street, Ashley, Luzerne County, PA

  13. 34. Coal Fuel Elevator (diagonal in foreground), Fuel Elevator (left), ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    34. Coal Fuel Elevator (diagonal in foreground), Fuel Elevator (left), Fuel Storage Bins (center), and Power Plant (far center), and Retail Coal Storage Bins (right) Photograph taken by George Harven - Huber Coal Breaker, 101 South Main Street, Ashley, Luzerne County, PA

  14. 180 degree view of Building 7 elevations, illustrating rear elevation ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    180 degree view of Building 7 elevations, illustrating rear elevation of two story unit type with one story step-down on street side. View facing east - Harbor Hills Housing Project, One & Two Story Townhouse Type, 26607 Western Avenue, Lomita, Los Angeles County, CA

  15. Early and late weight gain and the timing of puberty.

    PubMed

    Dunger, David B; Ahmed, M Lynn; Ong, Ken K

    2006-07-25

    Nutrition is an important regulator of the tempo of growth and obesity is usually associated with tall childhood stature and earlier pubertal development. Several longitudinal studies have demonstrated that timing of puberty is most closely linked to infancy weight gain: suggesting an early window for programming of growth and development. Earlier puberty in the UK MRC 1946 birth cohort was related to smaller size at birth and rapid growth between 0 and 2 years. Rapid early weight gain leads to taller childhood stature and higher insulin-like growth factor I (IGF-I) levels, possibly through early induction of growth hormone (GH) receptor numbers, and such children are also at risk of childhood obesity. In the Avon Longitudinal Study of Parents and Children, rapid infancy weight gain was associated with increased risk of obesity at 5 and 8 years, with evidence of insulin resistance, exaggerated adrenarche and reduced levels of sex hormone binding globulin (SHBG). Potentially the elevated IGF-I and adrenal androgen levels, increased aromatase activity and increased 'free' sex steroid levels consequent to lower SHBG levels could all promote activity of the GnRH pulse generator. In addition obese children have higher leptin levels, a proven permissive factor in initiating LH pulsatility. Obesity could also affect the rate of progression through puberty as nutrition and SHBG may act respectively as an accelerator and brake on peripheral sex steroid action. Early weight gain and early pubertal development might also be associated with loss of the pubertal growth spurt perhaps through obesity-related suppression of GH secretion. Trans-generational recurrence of low birth weight, early catch-up weight gain, earlier menarche, and shorter adult stature have been observed in women, and could contribute to the strong heritability in age at menarche. PMID:16824679

  16. Evaluation of temperature-enhanced gain degradation of verticle npn and lateral pnp bipolar transistors

    SciTech Connect

    Witczak, S.C.; Lacoe, R.C.; Galloway, K.F.

    1997-03-01

    The effect of dose rate on radiation-induced gain degradation is compared for verticle npn and lateral pnp bipolar transistors. High dose rate irradiations at elevated temperatures are more effective at simulating low dose rate degradation in the lateral pnp transistors.

  17. Estimated Effect of the Teacher Advancement Program on Student Test Score Gains

    ERIC Educational Resources Information Center

    Springer, Matthew G.; Ballou, Dale; Peng, Art

    2014-01-01

    This article presents findings from the first independent, third-party appraisal of the impact of the Teacher Advancement Program (TAP) on student test score gains in mathematics. TAP is a comprehensive school reform model designed to attract highly effective teachers, improve instructional effectiveness, and elevate student achievement. We use a

  18. Space Station tethered elevator system

    NASA Technical Reports Server (NTRS)

    Haddock, Michael H.; Anderson, Loren A.; Hosterman, K.; Decresie, E.; Miranda, P.; Hamilton, R.

    1989-01-01

    The optimized conceptual engineering design of a space station tethered elevator is presented. The tethered elevator is an unmanned, mobile structure which operates on a ten-kilometer tether spanning the distance between Space Station Freedom and a platform. Its capabilities include providing access to residual gravity levels, remote servicing, and transportation to any point along a tether. The report discusses the potential uses, parameters, and evolution of the spacecraft design. Emphasis is placed on the elevator's structural configuration and three major subsystem designs. First, the design of elevator robotics used to aid in elevator operations and tethered experimentation is presented. Second, the design of drive mechanisms used to propel the vehicle is discussed. Third, the design of an onboard self-sufficient power generation and transmission system is addressed.

  19. Weight gain associated with valproate in childhood.

    PubMed

    Demir, E; Aysun, S

    2000-05-01

    Weight gain is a common side effect of valproate treatment. Several mechanisms have been suggested for its pathophysiology; of these, impairment of beta-oxidation of fatty acids and increased insulin secretion have been supported by clinical studies. To investigate whether changes in carnitine and insulin levels had a role in the weight gain occurring with valproate treatment in children, 20 patients with epilepsy were randomly assigned to receive either carnitine or placebo supplementation in addition to valproate. After a follow-up period of 3 months, weight gain was observed in both groups. The mean insulin concentration and insulin/glucose ratios increased. Weight gain did not correlate with carnitine levels. These results suggest that weight gain during valproate treatment is not related to a decrease in carnitine levels. However, an increase in insulin levels together with a decrease in glucose levels may cause weight gain, possibly by stimulating appetite. PMID:10913727

  20. Gain and loss mechanisms in fluorocarbon plasmas

    NASA Astrophysics Data System (ADS)

    Nelson, Caleb Timothy

    Understanding dominant reaction channels for important gas-phase species in fluorocarbon plasmas is crucial to the ability to control surface evolution and morphology. In order to accomplish this goal a modified GEC reference ICP reactor is used in tandem with Fourier transform infrared spectroscopy (FTIR) to measure the densities of stable species. Integrated absorption cross-sections are presented for all fundamental bands in the 650 cm-1 to 2000 cm-1 region for C3F6, C4F 8, C3F8, C2F6, C2F 4, and CF4. The results show that although the absorption profile changes significantly, the integrated absorption cross-sections, with the exception of CF4, do not change significantly as gas temperature increases from 25°C to 200°C. However, the internal temperature of the absorbing species can be estimated from the rotational band maximum in most cases. Species densities obtained with the aforementioned cross-sections are used with a novel analysis technique to quantify gain and loss rates as functions of residence time, pressure, and deposited power. CF4, C2F6, C3F8, and C4F 10, share related production channels, which increase in magnitude as the plasma pressure, deposited power, or surface temperature are raised. CF 2 is primarily produced through a combination of surface production (the magnitude also increases with temperature) and electron impact dissociation of C2F4, while it is predominantly lost in the large reactor to gas-phase addition to form C2F4. Time-resolved FTIR results are used to measure a cross-section of 1.8x10-14 cm3/s for the reaction between CF2 radicals creating C2F4. Finally, C2F4 originates through the electron impact dissociation of c- C4F8. The loss process for C2F4 is undetermined, but the results indicate that it could occur on reactor surfaces. Neither the density of fluorine nor the ion flux to the chuck surface changes substantially with wall temperature. We show that increases in the deposition rate in a heated chamber are due to an increase in the fluxes of depositing neutral species. Furthermore, the sticking coefficient for these species does not change significantly as a function of surface temperature. Instead, surface temperature elevates the yield of etchant species, which terminate broken bonds to increase the desorption rates of stable species.

  1. Ka-band monolithic gain control amplifier

    NASA Technical Reports Server (NTRS)

    Geddes, J.; Sokolov, V.; Contolatis, T.

    1986-01-01

    A monolithic gain control amplifier for Ka-band has been developed based on 0.25 micron-gate-length dual-gate FETs fabricated on ion-implanted material. A single-stage monolithic amplifier gives a gain of 6 dB at 31 GHz including fixture losses with a gain control range of over 20 dB. The device and IC design and fabrication are described.

  2. 1. 'Front Elevation, End Elevation of Parapet, Section on Centerline ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. 'Front Elevation, End Elevation of Parapet, Section on Centerline of Portal,' Southern Pacific Standard Single-Track Tunnel, 1909. Compare to photos in documentation sets for Tunnel 23 (HAER No. CA-198), Tunnel 24 (HAER No. CA-200), Tunnel 25 (HAER No. CA-201), Tunnel 27 (HAER No. CA-203), Tunnel 28 (HAER No. CA-204), and Tunnel 29 (HAER No. CA-205). - Central Pacific Transcontinental Railroad, Sacramento to Nevada state line, Sacramento, Sacramento County, CA

  3. Actinide Thermodynamics at Elevated Temperatures

    SciTech Connect

    Friese, Judah I.; Rao, Linfeng; Xia, Yuanxian; Bachelor, Paula P.; Tian, Guoxin

    2007-11-16

    The postclosure chemical environment in the proposed Yucca Mountain repository is expected to experience elevated temperatures. Predicting migration of actinides is possible if sufficient, reliable thermodynamic data on hydrolysis and complexation are available for these temperatures. Data are scarce and scattered for 25 degrees C, and nonexistent for elevated temperatures. This collaborative project between LBNL and PNNL collects thermodynamic data at elevated temperatures on actinide complexes with inorganic ligands that may be present in Yucca Mountain. The ligands include hydroxide, fluoride, sulfate, phosphate and carbonate. Thermodynamic parameters of complexation, including stability constants, enthalpy, entropy and heat capacity of complexation, are measured with a variety of techniques including solvent extraction, potentiometry, spectrophotometry and calorimetry

  4. Elevation Derivatives for National Applications

    USGS Publications Warehouse

    U.S. Geological Survey

    2005-01-01

    The Elevation Derivatives for National Applications (EDNA) project is a multi-agency effort to develop standard topographically derived layers for use in hydrologic and environmental modeling. The EDNA takes advantage of the seamless and filtered characteristics for the National Elevation Dataset (NED) to create a hydrologically conditioned Digital Elevation Model (DEM) useful for modeling applications. The goals of the project are to create a hydrologically conditioned DEM and systematically extract a set of standard derivatives that can be used to facilitate data integration with other U.S. Geological Survey (USGS) framework data sets such as the National Hydrography Dataset (NHD) and the Watershed Boundaries Dataset (WBD).

  5. Orbital cellulitis with periosteal elevation.

    PubMed

    Lemke, B N; Gonnering, R S; Weinstein, J M

    1987-01-01

    Computerized tomography scan evidence of periosteal elevation in patients with orbital cellulitis is interpreted in the current medical literature as an indication of subperiosteal abscess. We present three such cases in which surgical drainage yielded clear fluid or granulation tissue rather than pus. A fourth case resolved on antibiotic therapy alone. Cases of periosteal elevation that resolve without surgery may represent inflammatory effusion, infections of lesser virulence, or propagation of granulation tissue rather than true abscesses. We suggest that periosteal elevation seen in patients with orbital cellulitis should represent a relative rather than an absolute indication for drainage surgery. PMID:3154568

  6. Moral elevation can induce nursing.

    PubMed

    Silvers, Jennifer A; Haidt, Jonathan

    2008-04-01

    There is little extant research on the psychological or physiological response to witnessing good deeds. The authors call the emotional reaction to virtue "moral elevation" and the authors examined its effects on mother-infant dyads. Breastfeeding women who watched a morally elevating video were more likely to nurse their infants and were marginally more likely to hug them, compared to women who watched an equally enjoyable comedy video. Both of these effects suggest that moral elevation may involve the release of oxytocin, a hormone associated with lactation and affiliation. PMID:18410202

  7. Meaningful Reading Gains by Adult Literacy Learners

    ERIC Educational Resources Information Center

    Scarborough, Hollis S.; Sabatini, John P.; Shore, Jane; Cutting, Laurie E.; Pugh, Kenneth; Katz, Leonard

    2013-01-01

    To obtain a fuller picture of the efficacy of reading instruction programs for adult literacy learners, gains by individual students were examined in a sample (n = 148) in which weak to moderate gains at the group level had been obtained in response to tutoring interventions that focused on strengthening basic decoding and fluency skills of low

  8. Correcting the Normalized Gain for Guessing

    ERIC Educational Resources Information Center

    Stewart, John; Stewart, Gay

    2010-01-01

    The normalized gain, "g", has been an important tool for the characterization of conceptual improvement in physics courses since its use in Hake's extensive study on conceptual learning in introductory physics. The normalized gain is calculated from the score on a pre-test administered before instruction and a post-test administered after…

  9. Gain calibration of CCD systems at VBO

    NASA Astrophysics Data System (ADS)

    Prabhu, T. P.; Mayya, Y. D.; Anupama, G. C.

    1992-03-01

    The system gain of two CCD systems in regular use at the Vainu Bappu Observatory, Kavalur, is determined at a few gain settings. The procedure used for the determination of system gain and base-level noise is described in detail. The Photometrics CCD system at the 1-m reflector uses a Thomson-CSF TH 7882 CDA chip coated for increased ultraviolet sensitivity. The gain is program-selected through the parameter 'cgain' varying between 0 and 4095 in steps of 1. The inverse system gain for this system varies almost linearly from 27.7 electrons/DN at cgain = 0 to 1.5 electrons/DN at cgain = 500. The readout noise is less than or approximately equal to 11 electrons at cgain = 66. The Astromed CCD system at 2.3-m Vainu Bappu Telescope uses a GEC P8603 chip which is also coated for enhanced ultraviolet sensitivity. The amplifier gain is selected in discrete steps using switches in the controller. The inverse system gain is 4.15 electrons/DN at the gain setting of 9.2, and the readout noise of about 8 electrons.

  10. GaInNAs laser gain

    SciTech Connect

    CHOW,WENG W.; JONES,ERIC D.; MODINE,NORMAND A.; KURTZ,STEVEN R.; ALLERMAN,ANDREW A.

    2000-05-23

    The optical gain spectra for GaInNAs/GaAs quantum wells are computed using a microscopic laser theory. From these spectra, the peak gain and carrier radiative decay rate as functions of carrier density are determined. These dependences allow the study of the lasing threshold current density of GaInNAs/GaAs quantum well structures.

  11. 75 FR 63763 - Program Integrity: Gainful Employment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-18

    ... Proposed Rulemaking on Program Integrity: Gainful Employment, published in the Federal Register on July 26, 2010 (75 FR 43616). DATES: The public meeting sessions will be held on the dates and at the locations... CFR Part 668 RIN 1840-AD04 Program Integrity: Gainful Employment AGENCY: Office of...

  12. Meaningful Reading Gains by Adult Literacy Learners

    ERIC Educational Resources Information Center

    Scarborough, Hollis S.; Sabatini, John P.; Shore, Jane; Cutting, Laurie E.; Pugh, Kenneth; Katz, Leonard

    2013-01-01

    To obtain a fuller picture of the efficacy of reading instruction programs for adult literacy learners, gains by individual students were examined in a sample (n = 148) in which weak to moderate gains at the group level had been obtained in response to tutoring interventions that focused on strengthening basic decoding and fluency skills of low…

  13. One-set resistance training elevates energy expenditure for 72 h similar to three sets

    PubMed Central

    Heden, Timothy; Lox, Curt; Rose, Paul; Reid, Steven

    2011-01-01

    To compare the effects of an acute one versus three-set full body resistance training (RT) bout in eight overweight (mean SD, BMI = 25.6 1.5 kg m?2) young (21.0 1.5 years) adults on resting energy expenditure (REE) measured on four consecutive mornings following each protocol. Participants performed a single one-set or three-set whole body (10 exercises, 10 repetition maximum) RT bout following the American College of Sports Medicine (ACSM) guidelines for RT. REE and respiratory exchange ratio (RER) by indirect calorimetry were measured at baseline and at 24, 48, and 72 h after the RT bout. Participants performed each protocol in randomized, counterbalanced order separated by 7 days. There was no difference between protocols for REE or RER. However, REE was significantly (p < 0.05) elevated (~5% or ~ 400 kJ day?1) in both the protocols at 24, 48, and 72 h post RT bout compared with baseline. There was a no change in RER in both the protocols at 72 h compared to baseline. A one-set RT bout following the ACSM guidelines for RT and requiring only ~ 15 min to complete was as effective as a three-set RT bout (~ 35 min to complete) in elevating REE for up to 72 h post RT in overweight college males, a group at high risk of developing obesity. The one-set RT protocol may provide an attractive alternative to either aerobic exercise or multiple-set RT programs for weight management in young adults, due to the minimal time commitment and the elevation in REE post RT bout. PMID:20886227

  14. Sudden Gains During Therapy of Social Phobia

    PubMed Central

    Hofmann, Stefan G.; Schulz, Stefan M.; Meuret, Alicia E.; Moscovitch, David A.; Suvak, Michael

    2007-01-01

    The present study investigated the phenomenon of sudden gains in 107 participants with social phobia (social anxiety disorder) who received either cognitivebehavioral group therapy or exposure group therapy without explicit cognitive interventions, which primarily used public speaking situations as exposure tasks. Twenty-two out of 967 session-to-session intervals met criteria for sudden gains, which most frequently occurred in Session 5. Individuals with sudden gains showed similar improvements in the 2 treatment groups. Although cognitivebehavioral therapy was associated with more cognitive changes than exposure therapy, cognitive changes did not precede sudden gains. In general, the results of this study question the clinical significance of sudden gains in social phobia treatment. PMID:16881776

  15. Lactate dehydrogenase-elevating virus

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This book chapter describes the taxonomic classification of Lactate dehydrogenase-elevating virus (LDV). Included are: host, genome, classification, morphology, physicochemical and physical properties, nucleic acid, proteins, lipids, carbohydrates, geographic range, phylogenetic properties, biologic...

  16. Area and mammalian elevational diversity.

    PubMed

    McCain, Christy M

    2007-01-01

    Elevational gradients hold enormous potential for understanding general properties of biodiversity. Like latitudinal gradients, the hypotheses for diversity patterns can be grouped into historical explanations, climatic drivers, and spatial hypotheses. The spatial hypotheses include the species-area effect and spatial constraint (mid-domain effect null models). I test these two spatial hypotheses using regional diversity patterns for mammals (non-volant small mammals and bats) along 34 elevational gradients spanning 24.4 degrees S-40.4 degrees N latitude. There was high variability in the fit to the species-area hypothesis and the mid-domain effect. Both hypotheses can be eliminated as primary drivers of elevational diversity. Area and spatial constraint both represent sources of error rather than mechanisms underlying these mammalian diversity patterns. Similar results are expected for other vertebrate taxa, plants, and invertebrates since they show comparable distributions of elevational diversity patterns to mammalian patterns. PMID:17489456

  17. Space Elevator: Path to Space

    NASA Astrophysics Data System (ADS)

    Kaushal, A. K.

    2012-05-01

    The Space Elevator is the most promising Space Transportation system on the drawing boards today, combining scalability, qualify of ride, and safety to deliver truly commercial-grade space access-practically comparable to a train ride to space.

  18. Space Elevators Preliminary Architectural View

    NASA Astrophysics Data System (ADS)

    Pullum, L.; Swan, P. A.

    Space Systems Architecture has been expanded into a process by the US Department of Defense for their large scale systems of systems development programs. This paper uses the steps in the process to establishes a framework for Space Elevator systems to be developed and provides a methodology to manage complexity. This new approach to developing a family of systems is based upon three architectural views: Operational View OV), Systems View (SV), and Technical Standards View (TV). The top level view of the process establishes the stages for the development of the first Space Elevator and is called Architectural View - 1, Overview and Summary. This paper will show the guidelines and steps of the process while focusing upon components of the Space Elevator Preliminary Architecture View. This Preliminary Architecture View is presented as a draft starting point for the Space Elevator Project.

  19. Space Elevator Base Leg Architecture

    NASA Astrophysics Data System (ADS)

    Swan, C.; Swan, P. A.

    While the Space Elevator stretches for 104,000 kilometers, the region of most concern, from the survival perspective, is 2,500 kms and below. The threats inside this dangerous arena include debris, spacecraft, meteorites, lightening, winds, rogue waves, aircraft, and intentional human acts. Two major questions will be addressed that will influence the overall systems architecture of a Space Elevator. While the deployment phase of the development of the Space Elevator will only have a single ribbon from the surface of the Earth to well beyond the Geosynchronous altitude, a mature Space Elevator must never allow a complete sever of the system. Design approaches, materials selections, international policy development and assembly must ensure that the integrity of the Space Elevator be maintained. The trade space analysis will address the probability of an individual ribbon being severed, the length of time to repair, and the potential for a catastrophic Space Elevator cut. The architecture proposed for the base leg portion will address two questions: Shall there be multiple base legs to 2,500 kms altitude? And Should the anchor be based on land or at sea?

  20. Controlling gain one photon at a time

    PubMed Central

    Schwartz, Gregory W; Rieke, Fred

    2013-01-01

    Adaptation is a salient property of sensory processing. All adaptational or gain control mechanisms face the challenge of obtaining a reliable estimate of the property of the input to be adapted to and obtaining this estimate sufficiently rapidly to be useful. Here, we explore how the primate retina balances the need to change gain rapidly and reliably when photons arrive rarely at individual rod photoreceptors. We find that the weakest backgrounds that decrease the gain of the retinal output signals are similar to those that increase human behavioral threshold, and identify a novel site of gain control in the retinal circuitry. Thus, surprisingly, the gain of retinal signals begins to decrease essentially as soon as background lights are detectable; under these conditions, gain control does not rely on a highly averaged estimate of the photon count, but instead signals from individual photon absorptions trigger changes in gain. DOI: http://dx.doi.org/10.7554/eLife.00467.001 PMID:23682314

  1. Active rc filter permits easy trade-off of amplifier gain and sensitivity to gain

    NASA Technical Reports Server (NTRS)

    Kerwin, W. J.; Shaffer, C. V.

    1968-01-01

    Passive RC network was designed with zeros of transmission in the right half of the complex frequency plane in the feedback loop of a simple negative-gain amplifier. The proper positioning provides any desired trade-off between amplifier gain and sensitivity to amplifier gain.

  2. Nonunity gain minimal-disturbance measurement

    SciTech Connect

    Sabuncu, Metin; Andersen, Ulrik L.; Mista, Ladislav Jr.; Fiurasek, Jaromir; Filip, Radim; Leuchs, Gerd

    2007-09-15

    We propose and experimentally demonstrate an optimal nonunity gain Gaussian scheme for partial measurement of an unknown coherent state that causes minimal disturbance of the state. The information gain and the state disturbance are quantified by the noise added to the measurement outcomes and to the output state, respectively. We derive the optimal trade-off relation between the two noises and we show that the tradeoff is saturated by nonunity gain teleportation. Optimal partial measurement is demonstrated experimentally using a linear optics scheme with feedforward.

  3. 2. 'Tunnel No 6 West End, Front Elevation, Sectional Elevation ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. 'Tunnel No 6 West End, Front Elevation, Sectional Elevation on Centerline of Portal,' Southern Pacific Standard Single-Track Tunnel, 1910. Tunnel 6, which today would be Tunnel 20, was daylighted and no longer exists. Compare to photos in documentation sets for Tunnel 23 (HAER No. CA-198), Tunnel 24 (HAER No. CA-200), Tunnel 25 (HAER No. CA-201), Tunnel 27 (HAER No. CA-203), Tunnel 28 (HAER No. CA-204), and Tunnel 29 (HAER No. CA-205). - Central Pacific Transcontinental Railroad, Sacramento to Nevada state line, Sacramento, Sacramento County, CA

  4. Elevated CO2 enhances biological contributions to elevation change in coastal wetlands by offsetting stressors associated with sea-level rise

    USGS Publications Warehouse

    Cherry, J.A.; McKee, K.L.; Grace, J.B.

    2009-01-01

    1. Sea-level rise, one indirect consequence of increasing atmospheric CO2, poses a major challenge to long-term stability of coastal wetlands. An important question is whether direct effects of elevated CO 2 on the capacity of marsh plants to accrete organic material and to maintain surface elevations outweigh indirect negative effects of stressors associated with sea-level rise (salinity and flooding). 2. In this study, we used a mesocosm approach to examine potential direct and indirect effects of atmospheric CO2 concentration, salinity and flooding on elevation change in a brackish marsh community dominated by a C3 species, Schoenoplectus americanus, and a C4 grass, Spartina patens. This experimental design permitted identification of mechanisms and their role in controlling elevation change, and the development of models that can be tested in the field. 3. To test hypotheses related to CO2 and sea-level rise, we used conventional anova procedures in conjunction with structural equation modelling (SEM). SEM explained 78% of the variability in elevation change and showed the direct, positive effect of S. americanus production on elevation. The SEM indicated that C3 plant response was influenced by interactive effects between CO2 and salinity on plant growth, not a direct CO2 fertilization effect. Elevated CO2 ameliorated negative effects of salinity on S. americanus and enhanced biomass contribution to elevation. 4. The positive relationship between S. americanus production and elevation change can be explained by shoot-base expansion under elevated CO 2 conditions, which led to vertical soil displacement. While the response of this species may differ under other environmental conditions, shoot-base expansion and the general contribution of C3 plant production to elevation change may be an important mechanism contributing to soil expansion and elevation gain in other coastal wetlands. 5. Synthesis. Our results revealed previously unrecognized interactions and mechanisms contributing to marsh elevation change, including amelioration of salt stress by elevated CO2 and the importance of plant production and shoot-base expansion for elevation gain. Identification of biological processes contributing to elevation change is an important first step in developing comprehensive models that permit more accurate predictions of whether coastal marshes will persist with continued sea-level rise or become submerged. ?? 2008 The Authors.

  5. Microwave gain medium with negative refractive index

    NASA Astrophysics Data System (ADS)

    Ye, Dexin; Chang, Kihun; Ran, Lixin; Xin, Hao

    2014-12-01

    Artificial effective media are attractive because of the fantastic applications they may enable, such as super lensing and electromagnetic invisibility. However, the inevitable loss due to their strongly dispersive nature is one of the fundamental challenges preventing such applications from becoming a reality. In this study, we demonstrate an effective gain medium based on negative resistance, to overcompensate the loss of a conventional passive metamaterial, meanwhile keeping its original negative-index property. Energy conservation-based theory, full-wave simulation and experimental measurement show that a fabricated sample consisting of conventional sub-wavelength building blocks with embedded microwave tunnel diodes exhibits a band-limited Lorentzian dispersion simultaneously with a negative refractive index and a net gain. Our work provides experimental evidence to the assertion that a stable net gain in negative-index gain medium is achievable, proposing a potential solution for the critical challenge current metamateiral technology faces in practical applications.

  6. Organic Causes of Weight Gain and Obesity

    MedlinePLUS

    ... Issues Listen Español Text Size Email Print Share Organic Causes of Weight Gain and Obesity Page Content ... as children, before they became heavy. Still other organic factors partly determine which kids can eat anything ...

  7. 34 CFR 462.43 - How is educational gain measured?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Educational Gain? § 462.43 How is educational gain measured? (a)(1) Educational gain is measured by comparing... educational functioning level. To measure educational gain, the local eligible provider would compare...

  8. 46 CFR 120.540 - Elevators.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Requirements 120.540 Elevators. Each elevator on a vessel must meet the requirements of American National Standards Institute (ANSI) A17.1. Safety Code for Elevators, and Escalators, or other standard...

  9. 46 CFR 120.540 - Elevators.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Requirements 120.540 Elevators. Each elevator on a vessel must meet the requirements of American National Standards Institute (ANSI) A17.1. Safety Code for Elevators, and Escalators, or other standard...

  10. 46 CFR 120.540 - Elevators.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Requirements 120.540 Elevators. Each elevator on a vessel must meet the requirements of American National Standards Institute (ANSI) A17.1. Safety Code for Elevators, and Escalators, or other standard...

  11. 46 CFR 120.540 - Elevators.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Requirements 120.540 Elevators. Each elevator on a vessel must meet the requirements of American National Standards Institute (ANSI) A17.1. Safety Code for Elevators, and Escalators, or other standard...

  12. 46 CFR 120.540 - Elevators.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Requirements 120.540 Elevators. Each elevator on a vessel must meet the requirements of American National Standards Institute (ANSI) A17.1. Safety Code for Elevators, and Escalators, or other standard...

  13. The Galileo high gain antenna deployment anomaly

    NASA Technical Reports Server (NTRS)

    Johnson, Michael R.

    1994-01-01

    On April 11, 1991, the Galileo spacecraft executed a sequence that would open the spacecraft's High Gain Antenna. The Antenna's launch restraint had been released just after deployment sequence, the antenna, which opens like an umbrella, never reached the fully deployed position. The analyses and tests that followed allowed a conclusive determination of the likely failure mechanisms and pointed to some strategies to use for recovery of the high gain antenna.

  14. Bulk photoconductive gain in pentacene thin films

    NASA Astrophysics Data System (ADS)

    Gao, J.; Hegmann, F. A.

    2008-12-01

    Bulk photoconductive gain greater than 16 is observed in pentacene thin films deposited onto coplanar interdigitated-electrode photodetector structures. The gain is highest at low light intensity but decreases at higher light intensity due to trap filling effects. The internal photogeneration quantum efficiency is found to be independent of wavelength below the absorption edge with the onset of photocurrent yield occurring at the absorption edge of the film.

  15. Universal scaling function for FEL gain

    SciTech Connect

    Yu, L.H.; Krinsky, S. ); Gluckstern, R.L. . Dept. of Physics and Astronomy)

    1990-01-01

    We have developed an analytic calculation of FEL gain in the exponential regime taking into account the finite emittance, energy spread, focusing and betatron oscillation of the electron beam, and the diffraction and guiding of the radiation. The gain is expressed in terms of a universal scaling function with only three independent parameters. Excellent agreement is found with results of numerical simulation. 14 refs., 3 figs., 1 tab.

  16. Can LENR Energy Gains Exceed 1000?

    NASA Astrophysics Data System (ADS)

    Nagel, David J.

    2011-03-01

    Energy gain is defined as the energy realized from reactions divided by the energy required to produce those reactions. Low Energy Nuclear Reactions (LENR) have already been measured to significantly exceed the energy gain of 10 projected from ITER,possibly 15 years from now. Electrochemical experiments using the Pd-D system have shown energy gains exceeding 10. Gas phase experiments with the Ni-H system were reported to yield energy gains of over 100. Neither of these reports has been adequately verified or reproduced. However, the question in the title still deserves consideration. If, as thought by many, it is possible to trigger nuclear reactions that yield MeV energies with chemical energies of the order of eV, then the most optimistic expectation is that LENR gains could approach one million. Hence, the very tentative answer to the question above is yes. However, if LENR could be initiated with some energy cost, and then continue to ``burn,'' very high energy gains might be realized. Consider a match and a pile of dry logs. The phenomenon termed ``heat after death'' will be examined to see if it might be the initial evidence for nuclear ``burning.''

  17. Central Gain Control in Tinnitus and Hyperacusis

    PubMed Central

    Auerbach, Benjamin D.; Rodrigues, Paulo V.; Salvi, Richard J.

    2014-01-01

    Sensorineural hearing loss induced by noise or ototoxic drug exposure reduces the neural activity transmitted from the cochlea to the central auditory system. Despite a reduced cochlear output, neural activity from more central auditory structures is paradoxically enhanced at suprathreshold intensities. This compensatory increase in the central auditory activity in response to the loss of sensory input is referred to as central gain enhancement. Enhanced central gain is hypothesized to be a potential mechanism that gives rise to hyperacusis and tinnitus, two debilitating auditory perceptual disorders that afflict millions of individuals. This review will examine the evidence for gain enhancement in the central auditory system in response to cochlear damage. Further, it will address the potential cellular and molecular mechanisms underlying this enhancement and discuss the contribution of central gain enhancement to tinnitus and hyperacusis. Current evidence suggests that multiple mechanisms with distinct temporal and spectral profiles are likely to contribute to central gain enhancement. Dissecting the contributions of these different mechanisms at different levels of the central auditory system is essential for elucidating the role of central gain enhancement in tinnitus and hyperacusis and, most importantly, the development of novel treatments for these disorders. PMID:25386157

  18. Context-specific adaptation of saccade gain

    NASA Technical Reports Server (NTRS)

    Shelhamer, Mark; Clendaniel, Richard A.

    2002-01-01

    Previous studies established that vestibular reflexes can have two adapted states (e.g., gain) simultaneously, and that a context cue (e.g., vertical eye position) can switch between the two states. The present study examined this phenomenon of context-specific adaptationfor horizontal saccades, using a variety of contexts. Our overall goal was to assess the efficacy of different context cues in switching between adapted states. A standard double-step paradigm was used to adapt saccade gain. In each experiment, we asked for a simultaneous gain decrease in one context and gain increase in another context, and then determined if a change in the context would invoke switching between the adapted states. Horizontal eye position worked well as a context cue: saccades with the eyes deviated to the right could be made to have higher gains while saccades with the eyes deviated to the left could be made to have lower gains. Vertical eye position was less effective. This suggests that the more closely related a context cue is to the response being adapted, the more effective it is. Roll tilt of the head, and upright versus supine orientations, were somewhat effective in context switching; these paradigms contain orientation of gravity with respect to the head as part of the context.

  19. Leaf conductance and carbon gain under salt-stressed conditions

    NASA Astrophysics Data System (ADS)

    Volpe, V.; Manzoni, S.; Marani, M.; Katul, G.

    2011-12-01

    Exposure of plants to salt stress is often accompanied by reductions in leaf photosynthesis and in stomatal and mesophyll conductances. To separate the effects of salt stress on these quantities, a model based on the hypothesis that carbon gain is maximized subject to a water loss cost is proposed. The optimization problem of adjusting stomatal aperture for maximizing carbon gain at a given water loss is solved for both a non-linear and a linear biochemical demand function. A key novel theoretical outcome of the optimality hypothesis is an explicit relationship between the stomatal and mesophyll conductances that can be evaluated against published measurements. The approaches here successfully describe gas-exchange measurements reported for olive trees (Olea europea L.) and spinach (Spinacia oleraceaL.) in fresh water and in salt-stressed conditions. Salt stress affected both stomatal and mesophyll conductances and photosynthetic efficiency of both species. The fresh water/salt water comparisons show that the photosynthetic capacity is directly reduced by 30%-40%, indicating that reductions in photosynthetic rates under increased salt stress are not due only to a limitation of CO2diffusion. An increase in salt stress causes an increase in the cost of water parameter (or marginal water use efficiency) exceeding 100%, analogous in magnitude to findings from extreme drought stress studies. The proposed leaf-level approach can be incorporated into physically based models of the soil-plant-atmosphere system to assess how saline conditions and elevated atmospheric CO2 jointly impact transpiration and photosynthesis.

  20. Mass Gains of the Antarctic Ice Sheet Exceed Losses

    NASA Technical Reports Server (NTRS)

    Zwally, H. Jay; Li, Jun; Robbins, John; Saba, Jack L.; Yi, Donghui; Brenner, Anita; Bromwich, David

    2012-01-01

    During 2003 to 2008, the mass gain of the Antarctic ice sheet from snow accumulation exceeded the mass loss from ice discharge by 49 Gt/yr (2.5% of input), as derived from ICESat laser measurements of elevation change. The net gain (86 Gt/yr) over the West Antarctic (WA) and East Antarctic ice sheets (WA and EA) is essentially unchanged from revised results for 1992 to 2001 from ERS radar altimetry. Imbalances in individual drainage systems (DS) are large (-68% to +103% of input), as are temporal changes (-39% to +44%). The recent 90 Gt/yr loss from three DS (Pine Island, Thwaites-Smith, and Marie-Bryd Coast) of WA exceeds the earlier 61 Gt/yr loss, consistent with reports of accelerating ice flow and dynamic thinning. Similarly, the recent 24 Gt/yr loss from three DS in the Antarctic Peninsula (AP) is consistent with glacier accelerations following breakup of the Larsen B and other ice shelves. In contrast, net increases in the five other DS of WA and AP and three of the 16 DS in East Antarctica (EA) exceed the increased losses. Alternate interpretations of the mass changes driven by accumulation variations are given using results from atmospheric-model re-analysis and a parameterization based on 5% change in accumulation per degree of observed surface temperature change. A slow increase in snowfall with climate waRMing, consistent with model predictions, may be offsetting increased dynamic losses.

  1. Analysis of a Space Elevator

    NASA Astrophysics Data System (ADS)

    Langston, J. L.

    2003-12-01

    This paper investigates the engineering principles that govern the design of a Space Elevator. The presentation includes extensive mathematical analysis of several basic approaches, reviews historical approaches and looks at some novel implementations. The technical challenges that must be overcome and the potential application of new technology to meet these challenges are discussed. While the paper focuses on the engineering aspects of the space elevator concept, some space is devoted to the potential use and benefit of a successful implementation. The primary objective of this paper is to show that no fundamental physical principles preclude the concept, but that technology development is required before a practical implementation can be realized.

  2. Tether Elevator Crawler Systems (TECS)

    NASA Technical Reports Server (NTRS)

    Swenson, Frank R.

    1987-01-01

    One of the needs of the experimenters on the space station is access to steady and controlled-variation microgravity environments. A method of providing these environments is to place the experiment on a tether attached to the space station. This provides a high degree of isolation from structural oscillations and vibrations. Crawlers can move these experiments along the tethers to preferred locations, much like an elevator. This report describes the motion control laws developed for these crawlers and the testing of laboratory models of these tether elevator crawlers.

  3. Edemagenic gain and interstitial fluid volume regulation.

    PubMed

    Dongaonkar, R M; Quick, C M; Stewart, R H; Drake, R E; Cox, C S; Laine, G A

    2008-02-01

    Under physiological conditions, interstitial fluid volume is tightly regulated by balancing microvascular filtration and lymphatic return to the central venous circulation. Even though microvascular filtration and lymphatic return are governed by conservation of mass, their interaction can result in exceedingly complex behavior. Without making simplifying assumptions, investigators must solve the fluid balance equations numerically, which limits the generality of the results. We thus made critical simplifying assumptions to develop a simple solution to the standard fluid balance equations that is expressed as an algebraic formula. Using a classical approach to describe systems with negative feedback, we formulated our solution as a "gain" relating the change in interstitial fluid volume to a change in effective microvascular driving pressure. The resulting "edemagenic gain" is a function of microvascular filtration coefficient (K(f)), effective lymphatic resistance (R(L)), and interstitial compliance (C). This formulation suggests two types of gain: "multivariate" dependent on C, R(L), and K(f), and "compliance-dominated" approximately equal to C. The latter forms a basis of a novel method to estimate C without measuring interstitial fluid pressure. Data from ovine experiments illustrate how edemagenic gain is altered with pulmonary edema induced by venous hypertension, histamine, and endotoxin. Reformulation of the classical equations governing fluid balance in terms of edemagenic gain thus yields new insight into the factors affecting an organ's susceptibility to edema. PMID:18056984

  4. New night vision goggle gain definition

    NASA Astrophysics Data System (ADS)

    Podobedov, Vyacheslav B.; Eppeldauer, George P.; Larason, Thomas C.

    2015-05-01

    A new definition is proposed for the calibration of Night Vision Goggle (NVG) gains. This definition is based on the measurement of radiometric input and output quantities of the NVG. While the old definition used the "equivalent fL" which is a non SI traceable luminance unit, the new definition utilizes the radiance quantities that are traceable to the SI units through NIST standards. The new NVG gain matches the previous one as a result of the application of a correction coefficient originating from the conversion of the radiance to luminance units. The new definition was tested at the NIST Night Vision Calibration Facility and the measurement results were compared to the data obtained with a Hoffman Test Set Model ANV-126. Comparing the radiometric quantities of the Hoffman Test Set and those measured by the NIST transfer standard radiometer, indicates that the observed differences up to 15% were due to the calibration and experimental errors of the ANV-126 Test Set. In view of different spectral characteristics of luminophores that can be utilized in the NVG design, the simulation of the NVG output for gain measurement was performed. The NVG output was simulated with a sphere-based source using different LEDs and the measured gain was compared to that obtained with the ANV-126 internal luminance meter. The NVG gain uncertainty analysis was performed for the Type A, B, and C goggles.

  5. Gain and energy storage in holmium YLF

    NASA Technical Reports Server (NTRS)

    Storm, Mark E.; Deyst, John P.

    1991-01-01

    It is demonstrated that Q-switched holmium lasers are capable of high-gain and high-energy operation at 300 K. Small-signal gain coefficients of 0.50 and 0.12/cm have been measured in YLF and YAG, respectively. Small-signal gains of 0.50/cm are comparable to those achievable in Nd:YAG and are not typical of low-gain materials. This large gain in the Ho:YLF material is made possible by operating the amplifier in the ground state depletion mode. The amplifier performance data and associated analysis presented demonstrate that efficient energy storage is possible with very high excited state ion densities of the Ho 5I7 upper laser level. This is an important result since upconversion can limit the 5I7 population. Although upconversion was still present in this experiment, it was possible to achieve efficient energy storage, demonstrating that the problem is manageable even at high excitation densities in YLF.

  6. Gain and energy storage in holmium YLF

    NASA Astrophysics Data System (ADS)

    Storm, Mark E.; Deyst, John P.

    1991-11-01

    It is demonstrated that Q-switched holmium lasers are capable of high-gain and high-energy operation at 300 K. Small-signal gain coefficients of 0.50 and 0.12/cm have been measured in YLF and YAG, respectively. Small-signal gains of 0.50/cm are comparable to those achievable in Nd:YAG and are not typical of low-gain materials. This large gain in the Ho:YLF material is made possible by operating the amplifier in the ground state depletion mode. The amplifier performance data and associated analysis presented demonstrate that efficient energy storage is possible with very high excited state ion densities of the Ho 5I7 upper laser level. This is an important result since upconversion can limit the 5I7 population. Although upconversion was still present in this experiment, it was possible to achieve efficient energy storage, demonstrating that the problem is manageable even at high excitation densities in YLF.

  7. Gain loss asymmetry for emerging stock markets

    NASA Astrophysics Data System (ADS)

    Karpio, Krzysztof; Za?uskaKotur, Magdalena A.; Or?owski, Arkadiusz

    2007-03-01

    Stock indexes for some European emerging markets are analyzed using an investment-horizon approach. Austrian ATX index and Dow Jones have been studied and compared with several emerging European markets. The optimal investment horizons are plotted as a function of an absolute return value. Gain-loss asymmetry, originally found for American DJIA index, is observed for all analyzed data. It is shown, that this asymmetry has different character for emerging and for established markets. For established markets, gain curve lies typically above loss curve, whereas in the case of emerging markets the situation is just the opposite. We propose a measure quantifying the gain-loss asymmetry that clearly exhibits a difference between emerging and established markets.

  8. Aromatic Gain in a Supramolecular Polymer.

    PubMed

    Saez Talens, Victorio; Englebienne, Pablo; Trinh, Thuat T; Noteborn, Willem E M; Voets, Ilja K; Kieltyka, Roxanne E

    2015-09-01

    The synergy of aromatic gain and hydrogen bonding in a supramolecular polymer is explored. Partially aromatic bis(squaramide) bolaamphiphiles were designed to self-assemble through a combination of hydrophobic, hydrogen-bonding, and aromatic effects into stiff, high-aspect-ratio fibers. UV and IR spectroscopy show electron delocalization and geometric changes within the squaramide ring indicative of strong hydrogen bonding and aromatic gain of the monomer units. The aromatic contribution to the interaction energy was further supported computationally by nucleus-independent chemical shift (NICS) and harmonic oscillator model of aromaticity (HOMA) indices, demonstrating greater aromatic character upon polymerization: at least 30% in a pentamer. The aromatic gain-hydrogen bonding synergy results in a significant increase in thermodynamic stability and a striking difference in aggregate morphology of the bis(squaramide) bolamphiphile compared to isosteres that cannot engage in this effect. PMID:26179942

  9. Gain Narrowing in Few-Atom Systems

    SciTech Connect

    Savels, Tom; Mosk, Allard P.; Lagendijk, Ad

    2007-03-09

    Using a density matrix approach, we study the simplest systems that display both gain and feedback: clusters of 2 to 5 atoms, one of which is pumped. The other atoms supply feedback through multiple scattering of light. We show that, if the atoms are in each other's near field, the system exhibits large gain narrowing and spectral mode redistribution. The observed phenomena are more pronounced if the feedback is enhanced. Our system is to our knowledge the simplest exactly solvable microscopic system which shows the approach to laser oscillation.

  10. Analytic gain in probabilistic decompression sickness models.

    PubMed

    Howle, Laurens E

    2013-11-01

    Decompression sickness (DCS) is a disease known to be related to inert gas bubble formation originating from gases dissolved in body tissues. Probabilistic DCS models, which employ survival and hazard functions, are optimized by fitting model parameters to experimental dive data. In the work reported here, I develop methods to find the survival function gain parameter analytically, thus removing it from the fitting process. I show that the number of iterations required for model optimization is significantly reduced. The analytic gain method substantially improves the condition number of the Hessian matrix which reduces the model confidence intervals by more than an order of magnitude. PMID:24209920

  11. Optimization Of Nakazima Test At Elevated Temperatures

    NASA Astrophysics Data System (ADS)

    Turetta, A.; Ghiotti, A.; Bruschi, S.

    2007-04-01

    Nowadays hot forming of High Strength Steel is gaining the strict requirements of automotive producer: in fact deformation performed simultaneously with quenching assures a fully martensitic microstructure at room temperature and thus high strength properties that allow the thickness reduction of the body-in-white components. Basic aspects of hot stamping are still under investigation and supplementary achievements are expected for a successful application of sheet metal forming technologies at elevated temperatures. Among data needed to settle a numerical model of the process, information about material formability may help in better designing and optimizing hot stamping operations. In the first part of the work, a new experimental apparatus based on Nakazima concept is presented; process parameters are optimized in order to accurately replicate the thermo-mechanical conditions typical of the industrial process, paying particular attention to the thermal and microstructural evolution. On the other hand, as commercial FE codes require the implementation of Forming Limit Diagrams at constant temperature, numerical investigations have been performed in order to determine the proper testing conditions to obtain FLD at nearly constant temperature.

  12. Optimization Of Nakazima Test At Elevated Temperatures

    SciTech Connect

    Turetta, A.; Ghiotti, A.; Bruschi, S.

    2007-04-07

    Nowadays hot forming of High Strength Steel is gaining the strict requirements of automotive producer: in fact deformation performed simultaneously with quenching assures a fully martensitic microstructure at room temperature and thus high strength properties that allow the thickness reduction of the body-in-white components. Basic aspects of hot stamping are still under investigation and supplementary achievements are expected for a successful application of sheet metal forming technologies at elevated temperatures. Among data needed to settle a numerical model of the process, information about material formability may help in better designing and optimizing hot stamping operations. In the first part of the work, a new experimental apparatus based on Nakazima concept is presented; process parameters are optimized in order to accurately replicate the thermo-mechanical conditions typical of the industrial process, paying particular attention to the thermal and microstructural evolution. On the other hand, as commercial FE codes require the implementation of Forming Limit Diagrams at constant temperature, numerical investigations have been performed in order to determine the proper testing conditions to obtain FLD at nearly constant temperature.

  13. Effect of periodic inflow on elevator traffic

    NASA Astrophysics Data System (ADS)

    Nagatani, Takashi; Tobita, Kazuhiro

    2012-09-01

    We study the dynamic behavior of an elevator induced by a periodic inflow of passengers. An elevator schedule is closely related to the dynamics. We present the modified circle map model for the dynamics of the elevator traffic. The motion of the elevator depends on both loading parameter and inflow period. The elevator displays the periodic and irregular motions with varying both loading parameter and inflow rate.

  14. Tapered InAs/InGaAs quantum dot semiconductor optical amplifier design for enhanced gain and beam quality.

    PubMed

    Mesaritakis, Charis; Kapsalis, Alexandros; Simos, Hercules; Simos, Christos; Krakowski, Michel; Krestnikov, Igor; Syvridis, Dimitris

    2013-07-15

    In this Letter, a design for a tapered InAs/InGaAs quantum dot semiconductor optical amplifier is proposed and experimentally evaluated. The amplifier's geometry was optimized in order to reduce gain saturation effects and improve gain efficiency and beam quality. The experimental measurements confirm that the proposed amplifier allows for an elevated optical gain in the saturation regime, whereas a five-fold increase in the coupling efficiency to a standard single mode optical fiber is observed, due to the improvement in the beam quality factor M of the emitted beam. PMID:23939062

  15. Pre-pregnancy obesity and maternal circadian cortisol regulation: Moderation by gestational weight gain.

    PubMed

    Aubuchon-Endsley, Nicki L; Bublitz, Margaret H; Stroud, Laura R

    2014-10-01

    We investigated main and interactive effects of maternal pre-pregnancy obesity and gestational weight gain on circadian cortisol from the second to third trimester. A diverse sample of 215 pregnant women was enrolled. Maternal height and most recent pre-pregnancy weight were collected at study initiation (22% obese). Weight and circadian salivary cortisol samples were measured during second (24±4) and third (35±1 weeks) trimesters. During the third trimester, women who were obese prior to conception showed elevated evening cortisol versus normal weight women. This pattern was moderated by weight gain in excess of Institute of Medicine guidelines, such that women who were obese prior to conception and gained greater than 7.94kg by the 35±1 week visit displayed greatest elevations in evening cortisol. Given links between excessive prenatal glucocorticoid exposure and both poor maternal and offspring health outcomes, elevated maternal cortisol may be one mechanism underlying links between maternal obesity and adverse perinatal outcomes. PMID:25038305

  16. Gravity referenced elevation encoder development

    NASA Technical Reports Server (NTRS)

    Goddard, R. E.

    1993-01-01

    Recent progress in the development of a gravity-sensor-based instrument for determining the elevation angle of DSN antennas is described. The benefits of such a system include the capability to locate the Gravity Referenced Elevation Encoder (GREE) directly on the primary reflector (thus bypassing structural flexure and deformation error sources), anticipated lower maintenance costs compared to the present gimbal encoders, direct replaceability, or supplementation of the present gimbal encoders and the utilization of off-the-shelf components to construct the GREE. This article includes a description of the nominal GREE design. Test results on a laboratory breadboard model are given. Rigid-body dynamics of the GREE are derived and the simulated performance in response to measured antenna vibrations is given.

  17. Science on a space elevator

    SciTech Connect

    Laubscher, B. E.; Jorgensen, A. M.

    2004-01-01

    The Space Elevator (SE) represents a major paradigm shift in space access. If the SE's promise of low cost access can be realized, everything becomes economically more feasible to accomplish in space. In this paper we describe in-situ science stations mounted on a science-dedicated space elevator tether. The concept presented here involves a carbon nanotube ribbon that is constructed by an existing space elevator and then science sensors are stationed along the ribbon at differing altitudes. The finished ribbon can be moved across the earth to the position at which its scientific measurements are to be taken. The ability to station scientific, in-situ instrumentation at different altitudes for round-the-clock observations is a unique capability of the SE. The environments that the science packages sense range from the troposphere out beyond the magnetopause of the magnetosphere on the solar side of the earth. Therefore, the very end of the SE can sense the solar wind. The measurements at various points along its length include temperature, pressure, density, sampling, chemical analyses, wind speed, turbulence, free oxygen, electromagnetic radiation, cosmic rays, energetic particles and plasmas in the earth's magnetosphere and the solar wind. There exist some altitudes that are difficult to access with aircraft or balloons or rockets and so remain relatively unexplored. The space elevator solves these problems and opens these regions up to in-situ measurements. Without the need for propulsion, the SE provides a more benign and pristine environment for atmospheric measurements than available with powered aircraft. Moreover, replacing and upgrading instrumentation is expected to be very cost effective with the SE. Moving and stationing the science SE affords the opportunity to sense multiple regions of the atmosphere. The SE's geosynchronous, orbital motion through the magnetosphere, albeit nominally with Earth's magnetic field, will trace a plane through that region once per day.

  18. Ion implantation at elevated temperatures

    SciTech Connect

    Lam, N.Q.; Leaf, G.K.

    1985-11-01

    A kinetic model has been developed to investigate the synergistic effects of radiation-enhanced diffusion, radiation-induced segregation and preferential sputtering on the spatial redistribution of implanted solutes during implantation at elevated temperatures. Sample calculations were performed for Al and Si ions implanted into Ni. With the present model, the influence of various implantation parameters on the evolution of implant concentration profiles could be examined in detail.

  19. Sudden Gains during Therapy of Social Phobia

    ERIC Educational Resources Information Center

    Hofmann, Stefan G.; Schultz, Stefan M.; Meuret, Alicia E.; Moscovitch, David A.; Suvak, Michael

    2006-01-01

    The present study investigated the phenomenon of sudden gains in 107 participants with social phobia (social anxiety disorder) who received either cognitive-behavioral group therapy or exposure group therapy without explicit cognitive interventions, which primarily used public speaking situations as exposure tasks. Twenty-two out of 967

  20. Pleasure Reading and Reading Rate Gains

    ERIC Educational Resources Information Center

    Beglar, David; Hunt, Alan

    2014-01-01

    This study investigated the effects of (a) the amount of pleasure reading completed, (b) the type of texts read (i.e., simplified or unsimplified books), and (c) the level of simplified texts read by 14 Japanese university students who made the largest reading rate gains over one academic year. The findings indicated that the participants who made

  1. Project GAIN Evaluation: 1969-70.

    ERIC Educational Resources Information Center

    Biller, Julian

    Project GAIN was designed to meet the special needs of the academically retarded junior high school student. This federally funded project has been on-going in Broward County (Florida) since January 1966. The project was conceived of as a means to motivate and educate those students whose "dull normal" intellectual ability might otherwise doom

  2. Texas Gains on NAEP: Points of Light?

    ERIC Educational Resources Information Center

    Camilli, Gregory

    2000-01-01

    Places the 1992-1996 gain in mathematics scores from Texas on the National Assessment of Educational Progress (NAEP) from fourth to eighth grades, asserting that the so-called miracle in Texas looks much like the median elsewhere. Texas ranks 17th among the 35 states and 2 districts with NAEP scores for the period, but Texas is no worse than most

  3. Gain of a single gas electron multiplier

    NASA Astrophysics Data System (ADS)

    Nemallapudi, Mythra Varun

    Gas Electron Multiplier (GEM) is a gaseous detector used in particle detection and is known for its high rate capability. Ever since its invention in 1997, GEM was applied in many areas and recently has been proposed to be installed in the CMS high ? regions for upgrade at LHC, CERN. A complete understanding of the working and gain behaviour does not exist. GEM gain is influenced by charging up and this has been variedly interpreted in literature lacking consensus. I have attempted in this work through simulations and measurements to achieve a better understanding of single GEM gain and how it is affected by various factors. Specific experimental methods which evolved with subsequent measurements were employed to systematically study the charging up effect. Information from simulations was applied to characterize measurements thereby enabling the development of a model for charging up. Conductivity mechanism of the dielectric used in GEM was analyzed and the resistivity measured. Gain free of charging up effects was measured and this is appropriate for comparison with simulations.

  4. Gain Scheduled Control and Related Topics

    NASA Astrophysics Data System (ADS)

    Uchida, Kenko

    From applications point of view in real plants, we review the gain-scheduled control that is based on linear parameter-varying systems modeling. We also discuss two related topics in control problems for systems with time-delay and in LQG controls.

  5. "Weighted" Funding of Schools Gains Favor

    ERIC Educational Resources Information Center

    Archer, Jeff

    2004-01-01

    In this article, the author describes how the "weighted student" funding, under which money is divvied up based on the actual number and kinds of students at each school, gains favor among education leaders. With weighted-student funding, a district divides up money--rather than staff positions and programs--among schools. Proponents also call it

  6. Gainful Employment: The Real Issue. Policy Memo

    ERIC Educational Resources Information Center

    Mandel, Michael

    2010-01-01

    Sometimes a proposed piece of legislation or new rule can catalyze debate about a key issue. That seems to be the case for the "gainful employment" rule currently being proposed by the Department of Education (DOE). The rule addresses a very real problem: The large amounts of debt being taken on by some students, mainly those attending for-profit

  7. X chromosome gain in male breast cancer.

    PubMed

    Di Oto, Enrico; Monti, Valentina; Cucchi, Maria C; Masetti, Riccardo; Varga, Zsuzsanna; Foschini, Maria P

    2015-12-01

    Male breast cancer (MBC) is an uncommon disease whose molecular profile is not well known. X chromosome gain has been described as a marker of aggressive behavior in female breast cancer. The aim of this study is to investigate the role of the X chromosome in male breast cancer. Twenty cases of male breast invasive ductal carcinoma were retrieved and compared with 10 cases of gynecomastia. Cases were tested by fluorescence in situ hybridization to assess a cytogenetic profile for the X chromosome. The X chromosome status was compared with histopathologic features and stage at presentation. All MBC cases harbored an X chromosome gain (100%) in a variable percentage of neoplastic cells, ranging from 31% to 85% (mean, 59%). On the contrary, all cases of gynecomastia showed wild X chromosome asset. The patients' age at surgery and tumor grading showed a statistically significant correlation (P = .0188-.04), with the percentages of neoplastic cells showing an X chromosome gain. These data suggest that this X chromosome gain plays a role in the neoplastic transformation of male breast epithelial cells. PMID:26475094

  8. Sudden Gains during Therapy of Social Phobia

    ERIC Educational Resources Information Center

    Hofmann, Stefan G.; Schultz, Stefan M.; Meuret, Alicia E.; Moscovitch, David A.; Suvak, Michael

    2006-01-01

    The present study investigated the phenomenon of sudden gains in 107 participants with social phobia (social anxiety disorder) who received either cognitive-behavioral group therapy or exposure group therapy without explicit cognitive interventions, which primarily used public speaking situations as exposure tasks. Twenty-two out of 967…

  9. Net Photorefractive Gain In Gallium Arsenide

    NASA Technical Reports Server (NTRS)

    Liu, Tsuen-Hsi; Cheng, Li-Jen

    1990-01-01

    Prerequisite includes applied electric field. Electric field applied to GaAs crystal in which two infrared beams interfere. Depending on quality of sample and experimental conditions, net photorefractive gain obtained. Results offer possibility of new developments in real-time optical processing of signals by use of near-infrared lasers of low power.

  10. Information gains from cosmic microwave background experiments

    NASA Astrophysics Data System (ADS)

    Seehars, Sebastian; Amara, Adam; Refregier, Alexandre; Paranjape, Aseem; Akeret, Jol

    2014-07-01

    To shed light on the fundamental problems posed by dark energy and dark matter, a large number of experiments have been performed and combined to constrain cosmological models. We propose a novel way of quantifying the information gained by updates on the parameter constraints from a series of experiments which can either complement earlier measurements or replace them. For this purpose, we use the Kullback-Leibler divergence or relative entropy from information theory to measure differences in the posterior distributions in model parameter space from a pair of experiments. We apply this formalism to a historical series of cosmic microwave background experiments ranging from Boomerang to WMAP, SPT, and Planck. Considering different combinations of these experiments, we thus estimate the information gain in units of bits and distinguish contributions from the reduction of statistical errors and the "surprise" corresponding to a significant shift of the parameters' central values. For this experiment series, we find individual relative entropy gains ranging from about 1 to 30 bits. In some cases, e.g. when comparing WMAP and Planck results, we find that the gains are dominated by the surprise rather than by improvements in statistical precision. We discuss how this technique provides a useful tool for both quantifying the constraining power of data from cosmological probes and detecting the tensions between experiments.

  11. Weight Gain Through Self-Control Procedures

    ERIC Educational Resources Information Center

    Gulanick, Nancy; And Others

    1975-01-01

    Underweight subjects were assigned to either a self-reinforcement condition, a self-punishment condition, or to a discussion/reflection control condition. The subjects received one treatment session per week over a five-week period. After treatment, the self-reinforcement groups gained significantly more pounds (kilograms) than either of the other

  12. Method and system for edge cladding of laser gain media

    DOEpatents

    Bayramian, Andrew James; Caird, John Allyn; Schaffers, Kathleen Irene

    2014-03-25

    A gain medium operable to amplify light at a gain wavelength and having reduced transverse ASE includes an input surface and an output surface opposing the input surface. The gain medium also includes a central region including gain material and extending between the input surface and the output surface along a longitudinal optical axis of the gain medium. The gain medium further includes an edge cladding region surrounding the central region and extending between the input surface and the output surface along the longitudinal optical axis of the gain medium. The edge cladding region includes the gain material and a dopant operable to absorb light at the gain wavelength.

  13. Counterbalancing Student Debt with "Asset Empowerment" and Economic Mobility

    ERIC Educational Resources Information Center

    Elliott, William; Chan, Monnica; Poore, Anthony

    2015-01-01

    Education provides one of the best opportunities for American children to build the capacity to climb up the economic ladder. It has even been called the "great equalizer" in American society. In today's tightened labor market, providing equal access to postsecondary education is more critical than ever. The Georgetown Center on…

  14. Counterbalancing Student Debt with "Asset Empowerment" and Economic Mobility

    ERIC Educational Resources Information Center

    Elliott, William; Chan, Monnica; Poore, Anthony

    2015-01-01

    Education provides one of the best opportunities for American children to build the capacity to climb up the economic ladder. It has even been called the "great equalizer" in American society. In today's tightened labor market, providing equal access to postsecondary education is more critical than ever. The Georgetown Center on

  15. Harvesting energy from the counterbalancing (weaving) movement in bicycle riding.

    PubMed

    Yang, Yoonseok; Yeo, Jeongjin; Priya, Shashank

    2012-01-01

    Bicycles are known to be rich source of kinetic energy, some of which is available for harvesting during speedy and balanced maneuvers by the user. A conventional dynamo attached to the rim can generate a large amount of output power at an expense of extra energy input from the user. However, when applying energy conversion technology to human powered equipments, it is important to minimize the increase in extra muscular activity and to maximize the efficiency of human movements. This study proposes a novel energy harvesting methodology that utilizes lateral oscillation of bicycle frame (weaving) caused by user weight shifting movements in order to increase the pedaling force in uphill riding or during quick speed-up. Based on the 3D motion analysis, we designed and implemented the prototype of an electro-dynamic energy harvester that can be mounted on the bicycle's handlebar to collect energy from the side-to-side movement. The harvester was found to generate substantial electric output power of 6.6 mW from normal road riding. It was able to generate power even during uphill riding which has never been shown with other approaches. Moreover, harvesting of energy from weaving motion seems to increase the economy of cycling by helping efficient usage of human power. PMID:23112598

  16. Harvesting Energy from the Counterbalancing (Weaving) Movement in Bicycle Riding

    PubMed Central

    Yang, Yoonseok; Yeo, Jeongjin; Priya, Shashank

    2012-01-01

    Bicycles are known to be rich source of kinetic energy, some of which is available for harvesting during speedy and balanced maneuvers by the user. A conventional dynamo attached to the rim can generate a large amount of output power at an expense of extra energy input from the user. However, when applying energy conversion technology to human powered equipments, it is important to minimize the increase in extra muscular activity and to maximize the efficiency of human movements. This study proposes a novel energy harvesting methodology that utilizes lateral oscillation of bicycle frame (weaving) caused by user weight shifting movements in order to increase the pedaling force in uphill riding or during quick speed-up. Based on the 3D motion analysis, we designed and implemented the prototype of an electro-dynamic energy harvester that can be mounted on the bicycle's handlebar to collect energy from the side-to-side movement. The harvester was found to generate substantial electric output power of 6.6 mW from normal road riding. It was able to generate power even during uphill riding which has never been shown with other approaches. Moreover, harvesting of energy from weaving motion seems to increase the economy of cycling by helping efficient usage of human power. PMID:23112598

  17. Estimating the rate and elevation dependence of net accretion in a freshwater tidal marsh using DEM-registered surveys

    NASA Astrophysics Data System (ADS)

    Cadol, D. D.; Elmore, A. J.; Engelhardt, K.; Sanders, G.

    2012-12-01

    Tidal freshwater marshes contribute to estuary health by filtering excess sediment and nutrients delivered from the watershed, but their extent and persistence is threatened by rising sea level. To maintain a semi-emergent position, the marsh surface must gain elevation by accreting mineral and/or organic material at a rate comparable to sea level rise. Historic records of sea level rise (SLR) are available from tide gages, but records of historic elevation change at the necessary precision are rare. Additionally, sedimentation, compaction, erosion, and the resultant net elevation gain are spatially heterogeneous across a marsh, varying with elevation, among other factors. We solve this issue at our study site by taking advantage of a 1992 total station survey of the marsh and RTK GPS surveys from 2005 and 2012, and registering them all against an airborne LiDAR derived DEM. Thus, although no points are directly reoccupied, survey vs. DEM trends can be found for each survey, and an average rate of elevation change can be calculated as a function of DEM elevation. We found rates of net elevation gain ranging spatially from 3-5 mm/yr between the years 1992-2012, similar to the historic rate of SLR at a nearby Washington, DC tide gage of 4 mm/yr over the past 28 years. Net elevation change varied as DEM elevation increased, with several local minima and maxima potentially related to variations and transitions in vegetation community. Assuming IPCC predicted sea level rise and a fixed relationship between elevation and net accretion, we then forecast marsh elevation relative to sea level and associated vegetative community changes through the 21st century using an inundation model that considers net accretion and a constant relationship between vegetation community type and elevation.

  18. Microbes on mountainsides: Contrasting elevational patterns of bacterial and plant diversity

    PubMed Central

    Bryant, Jessica A.; Lamanna, Christine; Morlon, Hélène; Kerkhoff, Andrew J.; Enquist, Brian J.; Green, Jessica L.

    2008-01-01

    The study of elevational diversity gradients dates back to the foundation of biogeography. Although elevational patterns of plant and animal diversity have been studied for centuries, such patterns have not been reported for microorganisms and remain poorly understood. Here, in an effort to assess the generality of elevational diversity patterns, we examined soil bacterial and plant diversity along an elevation gradient. To gain insight into the forces that structure these patterns, we adopted a multifaceted approach to incorporate information about the structure, diversity, and spatial turnover of montane communities in a phylogenetic context. We found that observed patterns of plant and bacterial diversity were fundamentally different. While bacterial taxon richness and phylogenetic diversity decreased monotonically from the lowest to highest elevations, plants followed a unimodal pattern, with a peak in richness and phylogenetic diversity at mid-elevations. At all elevations bacterial communities had a tendency to be phylogenetically clustered, containing closely related taxa. In contrast, plant communities did not exhibit a uniform phylogenetic structure across the gradient: they became more overdispersed with increasing elevation, containing distantly related taxa. Finally, a metric of phylogenetic beta-diversity showed that bacterial lineages were not randomly distributed, but rather exhibited significant spatial structure across the gradient, whereas plant lineages did not exhibit a significant phylogenetic signal. Quantifying the influence of sample scale in intertaxonomic comparisons remains a challenge. Nevertheless, our findings suggest that the forces structuring microorganism and macroorganism communities along elevational gradients differ. PMID:18695215

  19. 26 CFR 1.1287-1 - Denial of capital gains treatment for gains on registration-required obligations not in...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 11 2010-04-01 2010-04-01 true Denial of capital gains treatment for gains on registration-required obligations not in registered form. 1.1287-1 Section 1.1287-1 Internal Revenue INTERNAL... for Determining Capital Gains and Losses 1.1287-1 Denial of capital gains treatment for gains...

  20. Olanzapine depot exposure in male rats: Dose-dependent lipogenic effects without concomitant weight gain.

    PubMed

    Fernø, J; Ersland, K M; Duus, I H; González-García, I; Fossan, K O; Berge, R K; Steen, V M; Skrede, S

    2015-06-01

    Treatment with second-generation antipsychotic agents such as olanzapine frequently results in metabolic adverse effects, e.g. hyperphagia, weight gain and dyslipidaemia in patients of both genders. The molecular mechanisms underlying metabolic adverse effects are still largely unknown, and studies in rodents represent an important approach in their exploration. However, the validity of the rodent model is hampered by the fact that antipsychotics induce weight gain in female, but not male, rats. When administered orally, the short half-life of olanzapine in rats prevents stable plasma concentrations of the drug. We recently showed that a single intramuscular injection of long-acting olanzapine formulation yields clinically relevant plasma concentrations accompanied by several dysmetabolic features in the female rat. In the current study, we show that depot injections of 100-250 mg/kg olanzapine yielded clinically relevant plasma olanzapine concentrations also in male rats. In spite of transient hyperphagia, however, olanzapine resulted in weight loss rather than weight gain. The resultant negative feed efficiency was accompanied by a slight elevation of thermogenesis markers in brown adipose tissue for the highest olanzapine dose, but the olanzapine-related reduction in weight gain remains to be explained. In spite of the absence of weight gain, an olanzapine dose of 200mg/kg or above induced significantly elevated plasma cholesterol levels and pronounced activation of lipogenic gene expression in the liver. These results confirm that olanzapine stimulates lipogenic effects, independent of weight gain, and raise the possibility that endocrine factors may influence gender specificity of metabolic effects of antipsychotics in the rat. PMID:25823694

  1. Variable gain for a wind turbine pitch control

    NASA Technical Reports Server (NTRS)

    Seidel, R. C.; Birchenough, A. G.

    1981-01-01

    The gain variation is made in the software logic of the pitch angle controller. The gain level is changed depending upon the level of power error. The control uses low gain for low pitch activity the majority of the time. If the power exceeds ten percent offset above rated, the gain is increased to a higher gain to more effectively limit power. A variable gain control functioned well in tests on the Mod-0 wind turbine.

  2. Giant Raman gain in silicon nanocrystals

    NASA Astrophysics Data System (ADS)

    Sirleto, Luigi; Antonietta Ferrara, Maria; Nikitin, Timur; Novikov, Sergei; Khriachtchev, Leonid

    2012-11-01

    Nanostructured silicon has generated a lot of interest in the past decades as a key material for silicon-based photonics. The low absorption coefficient makes silicon nanocrystals attractive as an active medium in waveguide structures, and their third-order nonlinear optical properties are crucial for the development of next generation nonlinear photonic devices. Here we report the first observation of stimulated Raman scattering in silicon nanocrystals embedded in a silica matrix under non-resonant excitation at infrared wavelengths (~1.5??m). Raman gain is directly measured as a function of the silicon content. A giant Raman gain from the silicon nanocrystals is obtained that is up to four orders of magnitude greater than in crystalline silicon. These results demonstrate the first Raman amplifier based on silicon nanocrystals in a silica matrix, thus opening new perspectives for the realization of more efficient Raman lasers with ultra-small sizes, which would increase the synergy between electronic and photonic devices.

  3. Pole placement with constant gain output feedback

    NASA Technical Reports Server (NTRS)

    Sridhar, B.; Lindorff, D. P.

    1972-01-01

    Given a linear time invariant multivariable system with m inputs and p outputs, it was shown that p closed loop poles of the system can be preassigned arbitrarily using constant gain output feedback provided (A circumflex, B circumflex) is controllable. These data show that if (A circumflex, B circumflex, C circumflex) is controllable and observable, and Rank B circumflex = m, Rank C circumflex = p, then max (m,p) poles of the system can be assigned arbitarily using constant gain output feedback. Further, it is shown that in some cases more than max (m,p) poles can be arbitrarily assigned. A least square design technique is outlined to approximate the desired pole locations when it is not possible to place all the poles.

  4. Contrast Gain Control Model Fits Masking Data

    NASA Technical Reports Server (NTRS)

    Watson, Andrew B.; Solomon, Joshua A.; Null, Cynthia H. (Technical Monitor)

    1994-01-01

    We studied the fit of a contrast gain control model to data of Foley (JOSA 1994), consisting of thresholds for a Gabor patch masked by gratings of various orientations, or by compounds of two orientations. Our general model includes models of Foley and Teo & Heeger (IEEE 1994). Our specific model used a bank of Gabor filters with octave bandwidths at 8 orientations. Excitatory and inhibitory nonlinearities were power functions with exponents of 2.4 and 2. Inhibitory pooling was broad in orientation, but narrow in spatial frequency and space. Minkowski pooling used an exponent of 4. All of the data for observer KMF were well fit by the model. We have developed a contrast gain control model that fits masking data. Unlike Foley's, our model accepts images as inputs. Unlike Teo & Heeger's, our model did not require multiple channels for different dynamic ranges.

  5. Time ramped gain for borehole televiewer

    SciTech Connect

    Rambow, F.H.K.

    1989-08-08

    This patent describes an improvement in a borehole imaging apparatus wherein a rotating acoustic transducer means is periodically pulsed to emit a sequence of acoustic pulses into the borehole fluid toward the borehole wall and the reflected response of the acoustic pulse is received by the transducer means and converted to a related electrical signal. The improvement comprises: electrical signal compensating means located in the borehole for compensating substantially each of the electrical signals. The compensating means including variable gain amplifier means controllable from the surface for continuing to increase the amount of gain applied to each electrical signal as a function of the propagation time of the acoustic energy through the borehole fluid, to reduce the effects such as initial ringdown, mud reflections, and time-dependent borehole fluid attenuation of the acoustic energy.

  6. Loss/gain on ignition test report

    SciTech Connect

    Winstead, M.L.

    1996-01-10

    Document provides the results of tests done on Product Cans from the HC-21C sludge stabilization process. Tests included running a simulated Thermogravimetric Analysis, TGA, on the processed material that have received Loss On Ignition (LOI) sample results that show a gain on ignition or a high LOI and reprocessing product cans with high LOIs. Also, boat material temperatures in the furnace were tracked during the testing.

  7. Gain scaling for multirate filter banks

    SciTech Connect

    Brislawn, Christopher M

    2009-01-01

    Eliminating two trivial degrees of freedom corresponding to the lowpass DC response and the highpass Nyquist response in a two-channel multirate filter bank seems simple enough. Nonetheless, the ISO/IEC JPEG 2000 image coding standard manages to make this mundane task look totally mysterious. We reveal the true meaning behind JPEG 2000's arcane specifications for filter bank normalization and point out how the seemingly trivial matter of gain scaling leads to highly nontrivial issues concerning uniqueness of lifting factorizations.

  8. The Limits of the GAINS Spectrometer

    NASA Astrophysics Data System (ADS)

    Negret, A.; Borcea, C.; Dessagne, Ph.; Kerveno, M.; Nankov, N.; Nyman, M.; Olacel, A.; Plompen, A. J. M.; Rouki, C.

    2014-05-01

    The Gamma Array for Neutron Inelastic Scattering (GAINS) is currently operating at the GELINA (Geel Linear Accelerator) neutron source producing highly precise neutron inelastic scattering data. A series of recent investigations explored the limits of the experimental setup and technique. Measurements on 12C and 57Fe attempted the determination of very high and very low energy gamma production cross sections, respectively. An extended analysis was directed towards the generation of covariance matrices specifically for this experimental approach.

  9. High gain feedback and telerobotic tracking

    NASA Technical Reports Server (NTRS)

    Koditschek, D. E.

    1987-01-01

    Asymptotically stable linear time invariant systems are capable of tracking arbitrary reference signals with a bounded error proportional to the magnitude of the reference signal (and its derivatives). It is shown that a similar property holds for a general class of nonlinear dynamical systems which includes all robots. As in the linear case, the error bound may be made arbitrarily small by increasing the magnitude of the feedback gains which stabilize the system.

  10. Optical antenna gain. III - The effect of secondary element support struts on transmitter gain

    NASA Technical Reports Server (NTRS)

    Klein, B. J.; Degnan, J. J.

    1976-01-01

    The effect of a secondary-element spider support structure on optical antenna transmitter gain is analyzed. An expression describing the influence of the struts on the axial gain, in both the near and far fields, is derived as a function of the number of struts and their width. It is found that, for typical systems, the struts degrade the on-axis gain by less than 0.4 dB, and the first side-lobe level is not increased significantly. Contour plots have also been included to show the symmetry of the far-field distributions for three- and four-support members.

  11. Weight gain in adolescents and their peers.

    PubMed

    Halliday, Timothy J; Kwak, Sally

    2009-07-01

    Despite the urgent public health implications, relatively little is yet known about the effect of peers on adolescent weight gain. We describe trends and features of adolescent BMI in a nationally representative dataset and document correlations in weight gain among peers. We find strong correlations between own body mass index (BMI) and peers' BMI's. Though the correlations are especially strong in the upper ends of the BMI distribution, the relationship is smooth and holds over almost the entire range of adolescent BMI. Furthermore, the results are robust to the inclusion of school fixed effects and basic controls for other confounding factors such as race, sex, and age. Some recent research in this area considers whether or not adolescent weight gain is caused by peers. We discuss the econometric issues in plausibly estimating such effects while accounting for growth spurts and difficulties in defining adolescent obesity. While our work identifies correlations between adolescent BMI and peers' BMI, it is not intended to and cannot fully address the existence of endogenous peer effects. PMID:19497795

  12. Raman gains of ADP and KDP crystals

    NASA Astrophysics Data System (ADS)

    Zhou, Hai-Liang; Zhang, Qing-Hua; Wang, Bo; Xu, Xin-Guang; Wang, Zheng-Ping; Sun, Xun; Zhang, Fang; Zhang, Li-Song; Liu, Bao-An; Chai, Xiang-Xu

    2015-04-01

    In this paper, the Raman gain coefficients of ammonium dihydrogen phosphate (ADP) and potassium dihydrogen phosphate (KDP) crystals are measured. By using a pump source of a 30-ps, 532-nm laser, the gain coefficients of ADP and KDP are 1.22 cm/GW, and 0.91 cm/GW, respectively. While for a 20-ps, 355-nm pump laser, the gain coefficients of these two crystals are similar, which are 1.95 cm/GW for ADP and 1.86 for KDP. The present results indicate that for ultra-violet frequency conversion, the problem of stimulated Raman scattering for ADP crystal will not be more serious than that for KDP crystal. Considering other advantages such the larger nonlinear optical coefficient, higher laser damage threshold, and lower noncritical phase-matching temperature, it can be anticipated that ADP will be a powerful competitor to KDP in large aperture, high energy third-harmonic generation or fourth-harmonic generation applications. Project supported by the National Natural Science Foundation of China (Grant Nos. 51323002 and 51402173), the Independent Innovation Foundation of Shandong University, China (Grant Nos. IIFSDU and 2012JC016), the Program for New Century Excellent Talents in University, China (Grant No. NCET-10-0552), the Fund from the Key Laboratory of Neutron Physics, China Academy of Engineering Physics (Grant No. 2014BB07), and the Natural Science Foundation for Distinguished Young Scholar of Shandong Province, China (Grant No. JQ201218).

  13. Size at birth, weight gain in infancy and childhood, and adult blood pressure in 5 low- and middle-income-country cohorts: when does weight gain matter?123

    PubMed Central

    Martorell, Reynaldo; Stein, Aryeh D; Hallal, Pedro C; Sachdev, Harshpal S; Prabhakaran, Dorairaj; Wills, Andrew K; Norris, Shane A; Dahly, Darren L; Lee, Nanette R; Victora, Cesar G

    2009-01-01

    Background: Promoting catch-up growth in malnourished children has health benefits, but recent evidence suggests that accelerated child weight gain increases adult chronic disease risk. Objective: We aimed to determine how birth weight (BW) and weight gain to midchildhood relate to blood pressure (BP) in young adults. Design: We pooled data from birth cohorts in Brazil, Guatemala, India, the Philippines, and South Africa. We used conditional weight (CW), a residual of current weight regressed on prior weights, to represent deviations from expected weight gain from 0 to 12, 12 to 24, 24 to 48 mo, and 48 mo to adulthood. Adult BP and risk of prehypertension or hypertension (P/HTN) were modeled before and after adjustment for adult body mass index (BMI) and height. Interactions of CWs with small size-for-gestational age (SGA) at birth were tested. Results: Higher CWs were associated with increased BP and odds of P/HTN, with coefficients proportional to the contribution of each CW to adult BMI. Adjusted for adult height and BMI, no child CW was associated with adult BP, but 1 SD of BW was related to a 0.5-mm Hg lower systolic BP and a 9% lower odds of P/HTN. BW and CW associations with systolic BP and P/HTN were not different between adults born SGA and those with normal BW, but higher CW at 48 mo was associated with higher diastolic BP in those born SGA. Conclusions: Greater weight gain at any age relates to elevated adult BP, but faster weight gains in infancy and young childhood do not pose a higher risk than do gains at other ages. PMID:19297457

  14. Interventions to reduce weight gain in schizophrenia

    PubMed Central

    Faulkner, Guy; Cohn, Tony; Remington, Gary

    2014-01-01

    Background Weight gain is common for people with schizophrenia and this has serious implications for health and well being. Objectives To determine the effects of both pharmacological (excluding medication switching) and non pharmacological strategies for reducing or preventing weight gain in people with schizophrenia. Search methods We searched key databases and the Cochrane Schizophrenia Group’s trials register (April 2006), reference sections within relevant papers, hand searched key journals, and contacted the first author of each relevant study and other experts to collect further information. Selection criteria We included all clinical randomised controlled trials comparing any pharmacological or non pharmacological intervention for weight gain (diet and exercise counselling) with standard care or other treatments for people with schizophrenia or schizophrenia-like illnesses. Data collection and analysis We reliably selected, quality assessed and extracted data from studies. As weight is a continuous outcome measurement, weighted mean differences (WMD) of the change from baseline were calculated. The primary outcome measure was weight loss. Main results Twenty-three randomised controlled trials met the inclusion criteria for this review. Five trials assessed a cognitive/behavioural intervention and eighteen assessed a pharmacological adjunct. In terms of prevention, two cognitive/behavioural trials showed significant treatment effect (mean weight change) at end of treatment (n=104, 2 RCTs, WMD −3.38 kg CI −4.2 to −2.0). Pharmacological adjunct treatments were significant with a modest prevention of weight gain (n=274, 6 RCTs, WMD − 1.16 kg CI −1.9 to −0.4). In terms of treatments for weight loss, we found significantly greater weight reduction in the cognitive behavioural intervention group (n=129, 3 RCTs, WMD −1.69 kg CI −2.8 to −0.6) compared with standard care. Authors’ conclusions Modest weight loss can be achieved with selective pharmacological and non pharmacological interventions. However, interpretation is limited by the small number of studies, small sample size, short study duration and by variability of the interventions themselves, their intensity and duration. Future studies adequately powered, with longer treatment duration and rigorous methodology will be needed in further evaluating the efficacy and safety of weight loss interventions for moderating weight gain. At this stage, there is insufficient evidence to support the general use of pharmacological interventions for weight management in people with schizophrenia. PMID:17253540

  15. Effects of Gain Changes on RPM Performance

    SciTech Connect

    Lousteau, Angela L; York, Robbie Lynn; Livesay, Jake

    2012-03-01

    The mission of the U.S. Department of Energy/National Nuclear Security Administration's (DOE/NNSA's) Office of the Second Line of Defense (SLD) is to strengthen the capability of foreign governments to deter, detect, and interdict the illicit trafficking of special nuclear and other radioactive materials across international borders and through the global maritime shipping system. The goal of this mission is to reduce the probability of these materials being fashioned into a weapon of mass destruction or radiological dispersal device that could be used against the United States or its international partners. This goal is achieved primarily through the installation and operation of radiation detection equipment at border crossings, airports, seaports, and other strategic locations around the world. In order to effectively detect the movement of radioactive material, the response of these radiation detectors to various materials in various configurations must be well characterized. Oak Ridge National Laboratory (ORNL) investigated two aspects of Radiation Portal Monitor (RPM) settings, based on a preliminary investigation done by the Los Alamos National Laboratory (LANL): source-to-detector distance effect on amplifier gain and optimized discriminator settings. This report discusses this investigation. A number of conclusions can be drawn from the ORNL testing. First, for increased distance between the source and the detector, thus illuminating the entire detector rather than just the center of the detector (as is done during detector alignments), an increase in gain may provide a 5-15% increase in sensitivity (Fig. 4). However, increasing the gain without adjusting the discriminator settings is not recommended as this makes the monitor more sensitive to electronic noise and temperature-induced fluctuations. Furthermore, if the discriminators are adjusted in relation to the increase in gain, thus appropriately discriminating against electronic noise, the sensitivity gains are less than 5% (Fig. 6). ORNL does not consider this slight increase in sensitivity to be a worthwhile pursuit. Second, increasing the ULD will increase sensitivity a few percent (Fig. 7); however, it is not clear that the slight increase in sensitivity is worth the effort required to make the change (e.g., reliability, cost, etc.). Additionally, while the monitor would be more sensitive to HEU, it would also be more sensitive to NORM. Third, the sensitivity of the system remains approximately the same whether it is calibrated to a small source on contact or a large source far away (Fig. 6). This affirms that no changes to the existing calibration procedure are necessary.

  16. Repeatability of elevation measurements: Apollo photography

    NASA Technical Reports Server (NTRS)

    Wu, S. S. C.; Schafer, F. J.; Nakata, G. M.; Jordon, R.

    1973-01-01

    Sun elevation angle effects on repeatability, using Apollo 15 photographs are analyzed and results extended to slope related effects. Preliminary results indicate repeatibility of elevation measurement is related to contrast in the stereoscopic image.

  17. Intelligent elevator management system using image processing

    NASA Astrophysics Data System (ADS)

    Narayanan, H. Sai; Karunamurthy, Vignesh; Kumar, R. Barath

    2015-03-01

    In the modern era, the increase in the number of shopping malls and industrial building has led to an exponential increase in the usage of elevator systems. Thus there is an increased need for an effective control system to manage the elevator system. This paper is aimed at introducing an effective method to control the movement of the elevators by considering various cases where in the location of the person is found and the elevators are controlled based on various conditions like Load, proximity etc... This method continuously monitors the weight limit of each elevator while also making use of image processing to determine the number of persons waiting for an elevator in respective floors. Canny edge detection technique is used to find out the number of persons waiting for an elevator. Hence the algorithm takes a lot of cases into account and locates the correct elevator to service the respective persons waiting in different floors.

  18. Diffusion rates for elevated releases

    SciTech Connect

    Ramsdell, J.V.

    1983-11-01

    A search of the literature related to diffusion from elevated sources has determined that an adequate data base exists for use in developing parameterizations for estimating diffusion rates for material released from free standing stacks at nuclear power plants. A review of published data analyses indicates that a new parameterization of horizontal diffusion rates specifically for elevated releases is not likely to significantly change the magnitudes of horizontal diffusion coefficients on the average. However, the uncertainties associated with horizontal diffusion coefficient estimates under any given set of atmospheric conditions could be reduced by a new parameterization. Similarly, a new parameterization of vertical diffusion rates would be unlikely to significantly alter the magnitudes of diffusion coefficients for unstable atmospheric conditons. However, for neutral and stable atmospheric conditions, a new parameterization of vertical diffusion rates might increase vertical diffusion coefficients significantly. The increase would move ground-level time-integrated concentration maxima closer to the plant and would increase the maxima. 55 references, 2 figures, 4 tables.

  19. Approach to managing elevated creatinine.

    PubMed Central

    Tremblay, Richard

    2004-01-01

    OBJECTIVE: To describe a systematic approach to finding the underlying cause of an elevated creatinine level. QUALITY OF EVIDENCE: This diagnostic approach is based on a synthesis of information from reference works on nephrology, articles found through a MEDLINE search, and the author's personal experience. MAIN MESSAGE: Elevated creatinine levels suggest the differential diagnosis of renal failure (RF). History and a complete physical examination are important, keeping in mind that RF is often asymptomatic in the early stages. After repeating the creatinine test to verify results, baseline tests should be ordered to identify the cause of the RF. Comparing results of serial tests is essential for determining whether RF is acute or chronic, stable or progressive. An ultrasound scan is particularly useful for eliminating an obstructive cause; the size of the kidney can indicate whether disease is acute or chronic. Complementary blood tests and imaging studies might be useful. CONCLUSION: Diagnosing and managing RF can appear complex, but a systematic approach will help you find the cause and treat the condition. PMID:15171676

  20. The oscillating wing with aerodynamically balanced elevator

    NASA Technical Reports Server (NTRS)

    Kussner, H G; Schwartz, I

    1941-01-01

    The two-dimensional problem of the oscillating wing with aerodynamically balanced elevator is treated in the manner that the wing is replaced by a plate with bends and stages and the airfoil section by a mean line consisting of one or more straights. The computed formulas and tables permit, on these premises, the prediction of the pressure distribution and of the aerodynamic reactions of oscillating elevators and tabs with any position of elevator hinge in respect to elevator leading edge.

  1. Elevations and Distances in the United States.

    ERIC Educational Resources Information Center

    Geological Survey (Dept. of Interior), Reston, VA.

    One of a series of general interest publications on science topics, the booklet provides those interested in elevations and distances with a nontechnical introduction to the subject. The entire document consists of statistical charts depicting the nation's 50 largest cities, extreme and mean elevations, elevations of named summits over 14,000 feet

  2. Hurricane Katrina sediment slowed elevation loss in subsiding brackish marshes of the Mississippi River delta

    USGS Publications Warehouse

    McKee, K.L.; Cherry, J.A.

    2009-01-01

    Although hurricanes can damage or destroy coastal wetlands, they may play a beneficial role in reinvigorating marshes by delivering sediments that raise soil elevations and stimulate organic matter production. Hurricane Katrina altered elevation dynamics of two subsiding brackish marshes in the Mississippi River deltaic plain by adding 3 to 8 cm of sediment to the soil surface in August 2005. Soil elevations at both sites subsequently declined due to continued subsidence, but net elevation gain was still positive at both Pearl River (+1.7 cm) and Big Branch (+0.7 cm) marshes two years after the hurricane. At Big Branch where storm sediments had higher organic matter and water contents, post-storm elevation loss was more rapid due to initial compaction of the storm layer in combination with root-zone collapse. In contrast, elevation loss was slower at Pearl River where the storm deposit (high sand content) did not compact and the root zone did not collapse. Vegetation at both sites fully recovered within one year, and accumulation of root matter at Big Branch increased 10-fold from 2005 to 2006, suggesting that the hurricane stimulated belowground productivity. Results of this study imply that hurricane sediment may benefit subsiding marshes by slowing elevation loss. However, long-term effects of hurricane sediment on elevation dynamics will depend not only on the amount of sediment deposited, but on sediment texture and resistance to compaction as well as on changes in organic matter accumulation in the years following the hurricane.

  3. Neuronal Plasticity: Increasing the Gain in Pain

    NASA Astrophysics Data System (ADS)

    Woolf, Clifford J.; Salter, Michael W.

    2000-06-01

    We describe those sensations that are unpleasant, intense, or distressing as painful. Pain is not homogeneous, however, and comprises three categories: physiological, inflammatory, and neuropathic pain. Multiple mechanisms contribute, each of which is subject to or an expression of neural plasticity-the capacity of neurons to change their function, chemical profile, or structure. Here, we develop a conceptual framework for the contribution of plasticity in primary sensory and dorsal horn neurons to the pathogenesis of pain, identifying distinct forms of plasticity, which we term activation, modulation, and modification, that by increasing gain, elicit pain hypersensitivity.

  4. Semiconductor radiation detector with internal gain

    DOEpatents

    Iwanczyk, Jan (Los Angeles, CA); Patt, Bradley E. (Sherman Oaks, CA); Vilkelis, Gintas (Westlake Village, CA)

    2003-04-01

    An avalanche drift photodetector (ADP) incorporates extremely low capacitance of a silicon drift photodetector (SDP) and internal gain that mitigates the surface leakage current noise of an avalanche photodetector (APD). The ADP can be coupled with scintillators such as CsI(Tl), NaI(Tl), LSO or others to form large volume scintillation type gamma ray detectors for gamma ray spectroscopy, photon counting, gamma ray counting, etc. Arrays of the ADPs can be used to replace the photomultiplier tubes (PMTs) used in conjunction with scintillation crystals in conventional gamma cameras for nuclear medical imaging.

  5. SIMBAD4: Experiences Gained from the Development

    NASA Astrophysics Data System (ADS)

    Wenger, M.; Oberto, A.

    2007-10-01

    SIMBAD 4 will be operating shortly. This new release involves the JAVA language, a PostgreSQL database, and is running on a cluster of PCs running Linux. This is a very different schema from SIMBAD 3 (C language, object-oriented home-made database management system and one Sun Workstation). This leads to some comparisons and experiences gained from this new development. This paper present conclusions we draw from the design of SIMBAD 4 as well as comments about the first query performance results.

  6. Development of the Exercise Motives and Gains Inventory

    ERIC Educational Resources Information Center

    Strömmer, Sofia T.; Ingledew, David K.; Markland, David

    2015-01-01

    There are existing measures of exercise motives (what people want from exercise), but corresponding measures of gains (what people get) are needed, because motives and gains could influence each other and together influence other variables. An exercise motives and gains inventory (EMGI) was developed by creating gains scales to complement existing…

  7. IQ Gains in Argentina between 1964 and 1998

    ERIC Educational Resources Information Center

    Flynn, James R.; Rossi-Case, Lilia

    2012-01-01

    The literature on IQ gains in Latin America is sparse. We estimate gains on Raven's Progressive Matrices in the city of La Plata (Argentina) between 1964 and 1998. The gains are robust at the top of the curve as well as at the bottom. Therefore, they are contrary to the hypothesis that nutrition played a major role in recent Argentine IQ gains.

  8. IQ Gains in Argentina between 1964 and 1998

    ERIC Educational Resources Information Center

    Flynn, James R.; Rossi-Case, Lilia

    2012-01-01

    The literature on IQ gains in Latin America is sparse. We estimate gains on Raven's Progressive Matrices in the city of La Plata (Argentina) between 1964 and 1998. The gains are robust at the top of the curve as well as at the bottom. Therefore, they are contrary to the hypothesis that nutrition played a major role in recent Argentine IQ gains.…

  9. Development of the Exercise Motives and Gains Inventory

    ERIC Educational Resources Information Center

    Strmmer, Sofia T.; Ingledew, David K.; Markland, David

    2015-01-01

    There are existing measures of exercise motives (what people want from exercise), but corresponding measures of gains (what people get) are needed, because motives and gains could influence each other and together influence other variables. An exercise motives and gains inventory (EMGI) was developed by creating gains scales to complement existing

  10. Elevation Map of Kathmandu, Nepal

    NASA Technical Reports Server (NTRS)

    2002-01-01

    These Shuttle Radar Topgraphy Mission (SRTM) images show the basin of Kathmandu, the capital of Nepal: On the left a detail (27 km x 20.5 km) of the X-SAR digital elevation model (shown below), on the right the corresponding radar amplitude image. The amplitude is a measure of the backscattering of the transmitted microwaves. In the amplitude image the 'Bagmati-River' is visible south of the city center and the international Airport in the eastern part. The runway appears as a dark stripe. The airport is infamous for its difficult landing/takeoff conditions due to the close vicinity of the surrounding high mountains. For more information and a image of the region around Kathmandu, visit the German Remote Sensing Data Center SRTM Treasure Vault. Image courtesy German Remote Sensing Data Center

  11. Net gain in small mode volume organic microcavities

    NASA Astrophysics Data System (ADS)

    Tzschaschel, C.; Sudzius, M.; Mischok, A.; Fröb, H.; Leo, K.

    2016-01-01

    We report a room temperature study of net gain far below the lasing threshold in planar organic microresonators with a limited amount of gain material. We measure the net gain change as a function of optical pump power for various resonator designs and cavity thicknesses by carefully analyzing spatially filtered emission spectra of the microcavity using a transfer-matrix approach. We show that the net gain increases with pump prior to saturation of the gain material and photobleaching of population inversion. The time-integrated peak gain value of DCM based gain medium is estimated to be at least 380 cm-1 for our structures.

  12. Elevation dependency of mountain snow depth

    NASA Astrophysics Data System (ADS)

    Grünewald, T.; Bühler, Y.; Lehning, M.

    2014-07-01

    Elevation strongly affects quantity and distribution of precipitation and snow. Positive elevation gradients were identified by many studies, usually based on data from sparse precipitation stations or snow depth measurements. We present a systematic evaluation of the elevation - snow depth relationship. We analyse areal snow depth data obtained by remote sensing for seven mountain sites. Snow depths were averaged to 100 m elevation bands and then related to their respective elevation level. The assessment was performed at three scales ranging from the complete data sets by km-scale sub-catchments to slope transects. We show that most elevation - snow depth curves at all scales are characterised through a single shape. Mean snow depths increase with elevation up to a certain level where they have a distinct peak followed by a decrease at the highest elevations. We explain this typical shape with a generally positive elevation gradient of snow fall that is modified by the interaction of snow cover and topography. These processes are preferential deposition of precipitation and redistribution of snow by wind, sloughing and avalanching. Furthermore we show that the elevation level of the peak of mean snow depth correlates with the dominant elevation level of rocks.

  13. Elevation dependency of mountain snow depth

    NASA Astrophysics Data System (ADS)

    Grünewald, T.; Bühler, Y.; Lehning, M.

    2014-12-01

    Elevation strongly affects quantity and distribution patterns of precipitation and snow. Positive elevation gradients were identified by many studies, usually based on data from sparse precipitation stations or snow depth measurements. We present a systematic evaluation of the elevation-snow depth relationship. We analyse areal snow depth data obtained by remote sensing for seven mountain sites near to the time of the maximum seasonal snow accumulation. Snow depths were averaged to 100 m elevation bands and then related to their respective elevation level. The assessment was performed at three scales: (i) the complete data sets (10 km scale), (ii) sub-catchments (km scale) and (iii) slope transects (100 m scale). We show that most elevation-snow depth curves at all scales are characterised through a single shape. Mean snow depths increase with elevation up to a certain level where they have a distinct peak followed by a decrease at the highest elevations. We explain this typical shape with a generally positive elevation gradient of snow fall that is modified by the interaction of snow cover and topography. These processes are preferential deposition of precipitation and redistribution of snow by wind, sloughing and avalanching. Furthermore, we show that the elevation level of the peak of mean snow depth correlates with the dominant elevation level of rocks (if present).

  14. 1-Meter Digital Elevation Model specification

    USGS Publications Warehouse

    Arundel, Samantha T.; Archuleta, Christy-Ann M.; Phillips, Lori A.; Roche, Brittany L.; Constance, Eric W.

    2015-01-01

    In January 2015, the U.S. Geological Survey National Geospatial Technical Operations Center began producing the 1-Meter Digital Elevation Model data product. This new product was developed to provide high resolution bare-earth digital elevation models from light detection and ranging (lidar) elevation data and other elevation data collected over the conterminous United States (lower 48 States), Hawaii, and potentially Alaska and the U.S. territories. The 1-Meter Digital Elevation Model consists of hydroflattened, topographic bare-earth raster digital elevation models, with a 1-meter x 1-meter cell size, and is available in 10,000-meter x 10,000-meter square blocks with a 6-meter overlap. This report details the specifications required for the production of the 1-Meter Digital Elevation Model.

  15. Autonomic and prefrontal events during moral elevation.

    PubMed

    Piper, Walter T; Saslow, Laura R; Saturn, Sarina R

    2015-05-01

    Moral elevation, or elevation, is a specific emotional state triggered by witnessing displays of profound virtue and moral beauty. This study set out to characterize the physiology underlying elevation with measurements of heart rate (HR), respiratory sinus arrhythmia (RSA), and medial prefrontal cortex (mPFC) activity. During elevation, HR and RSA increased. These findings illustrate that elevation involves an uncommon combination of both sympathetic and parasympathetic activation, which is present in circumstances where arousal and social engagement are both required. In addition, we show evidence of content-dependent alterations of mPFC activity during elevation peaks. Altogether, this study shows that the induction of moral elevation recruits an uncommon autonomic and neural pattern that is consistent with previous understanding of socioemotional-induced allostasis. PMID:25813121

  16. Determinants of Weight Gain in the Action to Control Cardiovascular Risk in Diabetes Trial

    PubMed Central

    Fonseca, Vivian; McDuffie, Roberta; Calles, Jorge; Cohen, Robert M.; Feeney, Patricia; Feinglos, Mark; Gerstein, Hertzel C.; Ismail-Beigi, Faramarz; Morgan, Timothy M.; Pop-Busui, Rodica; Riddle, Matthew C.

    2013-01-01

    OBJECTIVE Identify determinants of weight gain in people with type 2 diabetes mellitus (T2DM) allocated to intensive versus standard glycemic control in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial. RESEARCH DESIGN AND METHODS We studied determinants of weight gain over 2 years in 8,929 participants (4,425 intensive arm and 4,504 standard arm) with T2DM in the ACCORD trial. We used general linear models to examine the association between each baseline characteristic and weight change at the 2-year visit. We fit a linear regression of change in weight and A1C and used general linear models to examine the association between each medication at baseline and weight change at the 2-year visit, stratified by glycemia allocation. RESULTS There was significantly more weight gain in the intensive glycemia arm of the trial compared with the standard arm (3.0 ± 7.0 vs. 0.3 ± 6.3 kg). On multivariate analysis, younger age, male sex, Asian race, no smoking history, high A1C, baseline BMI of 25–35, high waist circumference, baseline insulin use, and baseline metformin use were independently associated with weight gain over 2 years. Reduction of A1C from baseline was consistently associated with weight gain only when baseline A1C was elevated. Medication usage accounted for <15% of the variability of weight change, with initiation of thiazolidinedione (TZD) use the most prominent factor. Intensive participants who never took insulin or a TZD had an average weight loss of 2.9 kg during the first 2 years of the trial. In contrast, intensive participants who had never previously used insulin or TZD but began this combination after enrolling in the ACCORD trial had a weight gain of 4.6–5.3 kg at 2 years. CONCLUSIONS Weight gain in ACCORD was greater with intensive than with standard treatment and generally associated with reduction of A1C from elevated baseline values. Initiation of TZD and/or insulin therapy was the most important medication-related factor associated with weight gain. PMID:23412077

  17. Combining earthquake forecasts using differential probability gains

    NASA Astrophysics Data System (ADS)

    Shebalin, Peter N.; Narteau, Clément; Zechar, Jeremy Douglas; Holschneider, Matthias

    2014-12-01

    We describe an iterative method to combine seismicity forecasts. With this method, we produce the next generation of a starting forecast by incorporating predictive skill from one or more input forecasts. For a single iteration, we use the differential probability gain of an input forecast relative to the starting forecast. At each point in space and time, the rate in the next-generation forecast is the product of the starting rate and the local differential probability gain. The main advantage of this method is that it can produce high forecast rates using all types of numerical forecast models, even those that are not rate-based. Naturally, a limitation of this method is that the input forecast must have some information not already contained in the starting forecast. We illustrate this method using the Every Earthquake a Precursor According to Scale (EEPAS) and Early Aftershocks Statistics (EAST) models, which are currently being evaluated at the US testing center of the Collaboratory for the Study of Earthquake Predictability. During a testing period from July 2009 to December 2011 (with 19 target earthquakes), the combined model we produce has better predictive performance - in terms of Molchan diagrams and likelihood - than the starting model (EEPAS) and the input model (EAST). Many of the target earthquakes occur in regions where the combined model has high forecast rates. Most importantly, the rates in these regions are substantially higher than if we had simply averaged the models.

  18. Automatic gain control for Raman lidar signals

    NASA Astrophysics Data System (ADS)

    Lay-Ekuakille, Aimé; Vendramin, Giuseppe; Trotta, Amerigo

    2008-12-01

    Electronic component improvements allow everyone to use them for performing new features in different applications. Lidar signal control is matter of continuous design and it can be studied in order to increase signal-to-noise ratio. Fortunately, the advent, of programmable gain amplifiers, switching capacitor filters and specific AD converters, is the stimulus of improving lidar signal quality. The main scope of this paper is to design and to realize a hardware simulator capable of reproducing the behavior of lidar signal control. This paper aims at describing the results of an automatic control system for Raman lidar signals. The system is based on the following units: laser source, damper, PMT (Photomultiplier), current - to - voltage converter, switched capacitor filter, programmable gain amplifier, A/D converter and FIR filter. This configuration allows the use of FIR filter that is not strictly necessary but it can help in adapting signal according to the amplitude. One of the main advantage of this system is to obtain a flexible and programmable board.

  19. Gain-assisted superluminal light propagation

    PubMed

    Wang; Kuzmich; Dogariu

    2000-07-20

    Einstein's theory of special relativity and the principle of causality imply that the speed of any moving object cannot exceed that of light in a vacuum (c). Nevertheless, there exist various proposals for observing faster-than-c propagation of light pulses, using anomalous dispersion near an absorption line, nonlinear and linear gain lines, or tunnelling barriers. However, in all previous experimental demonstrations, the light pulses experienced either very large absorption or severe reshaping, resulting in controversies over the interpretation. Here we use gain-assisted linear anomalous dispersion to demonstrate superluminal light propagation in atomic caesium gas. The group velocity of a laser pulse in this region exceeds c and can even become negative, while the shape of the pulse is preserved. We measure a group-velocity index of n(g) = -310(+/- 5); in practice, this means that a light pulse propagating through the atomic vapour cell appears at the exit side so much earlier than if it had propagated the same distance in a vacuum that the peak of the pulse appears to leave the cell before entering it. The observed superluminal light pulse propagation is not at odds with causality, being a direct consequence of classical interference between its different frequency components in an anomalous dispersion region. PMID:10917523

  20. Risk Insights Gained from Fire Incidents

    SciTech Connect

    Kazarians, Mardy; Nowlen, Steven P.

    1999-06-10

    There now exist close to 20 years of history in the application of Probabilistic Risk Assessment (PRA) for the analysis of fire risk at nuclear power plants. The current methods are based on various assumptions regarding fire phenomena, the impact of fire on equipment and operator response, and the overall progression of a fire event from initiation through final resolution. Over this same time period, a number of significant fire incidents have occurred at nuclear power plants around the world. Insights gained from US experience have been used in US studies as the statistical basis for establishing fire initiation frequencies both as a function of the plant area and the initiating fire source.To a lesser extent, the fire experience has also been used to assess the general severity and duration of fires. However, aside from these statistical analyses, the incidents have rarely been scrutinized in detail to verify the underlying assumptions of fire PRAs. This paper discusses an effort, under which a set of fire incidents are being reviewed in order to gain insights directly relevant to the methods, data, and assumptions that form the basis for current fire PRAs. The paper focuses on the objectives of the effort, the specific fire events being reviews methodology, and anticipated follow-on activities.

  1. Compensated gain control circuit for buck regulator command charge circuit

    DOEpatents

    Barrett, David M. (Albuquerque, NM)

    1996-01-01

    A buck regulator command charge circuit includes a compensated-gain control signal for compensating for changes in the component values in order to achieve optimal voltage regulation. The compensated-gain control circuit includes an automatic-gain control circuit for generating a variable-gain control signal. The automatic-gain control circuit is formed of a precision rectifier circuit, a filter network, an error amplifier, and an integrator circuit.

  2. Compensated gain control circuit for buck regulator command charge circuit

    DOEpatents

    Barrett, D.M.

    1996-11-05

    A buck regulator command charge circuit includes a compensated-gain control signal for compensating for changes in the component values in order to achieve optimal voltage regulation. The compensated-gain control circuit includes an automatic-gain control circuit for generating a variable-gain control signal. The automatic-gain control circuit is formed of a precision rectifier circuit, a filter network, an error amplifier, and an integrator circuit. 5 figs.

  3. Water quality in Gaines Creek and Gaines Creek arm of Eufaula Lake, Oklahoma

    USGS Publications Warehouse

    Kurklin, J.K.

    1990-01-01

    Based on samples collected from May 1978 to May 1980 and analyzed for major anions, nitrogen, trace elements, phytoplankton, and bacteria, the water in Gaines Creek and the Gaines Creek arm of Eufaula Lake was similar with respect to suitability for municipal use. Water from Gaines Creek had a pH range of 5.7 to 7.6 and a maximum specific conductance of 97 microsiemens per centimeter at 25o Celsius, whereas water from the Gaines Creek arm of Eufaula Lake had a pH range of 6.0 to 9.2 and a maximum specific conductance of 260 microsiemens per centimeter at 25o Celsius. Dissolved oxygen, pH, temperature, and specific conductance values for the lake varied with depth. With the exceptions of cadmium, iron, lead, and manganese, trace-element determinations of samples were within recommended national primary and secondary drinking-water standards. When compared to the National Academy of Sciences water-quality criteria, phytoplankton and bacteria counts exceeded recommendations; however, water from either Gaines Creek or Eufaula Lake could be treated similarly and used as a municipal water supply.

  4. 26 CFR 1.1287-1 - Denial of capital gains treatment for gains on registration-required obligations not in...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 11 2014-04-01 2014-04-01 false Denial of capital gains treatment for gains on registration-required obligations not in registered form. 1.1287-1 Section 1.1287-1 Internal Revenue INTERNAL...) Special Rules for Determining Capital Gains and Losses 1.1287-1 Denial of capital gains treatment...

  5. 26 CFR 1.1287-1 - Denial of capital gains treatment for gains on registration-required obligations not in...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 11 2013-04-01 2013-04-01 false Denial of capital gains treatment for gains on registration-required obligations not in registered form. 1.1287-1 Section 1.1287-1 Internal Revenue INTERNAL...) Special Rules for Determining Capital Gains and Losses 1.1287-1 Denial of capital gains treatment...

  6. Dynamic multibody modeling for tethered space elevators

    NASA Astrophysics Data System (ADS)

    Williams, Paul

    2009-08-01

    This paper presents a fundamental modeling strategy for dealing with powered and propelled bodies moving along space tethers. The tether is divided into a large number of discrete masses, which are connected by viscoelastic springs. The tether is subject to the full range of forces expected in Earth orbit in a relatively simple manner. Two different models of the elevator dynamics are presented. In order to capture the effect of the elevator moving along the tether, the elevator dynamics are included as a separate body in both models. One model treats the elevator's motion dynamically, where propulsive and friction forces are applied to the elevator body. The second model treats the elevator's motion kinematically, where the distance along the tether is determined by adjusting the lengths of tether on either side of the elevator. The tether model is used to determine optimal configurations for the space elevator. A modal analysis of two different configurations is presented which show that the fundamental mode of oscillation is a pendular one around the anchor point with a period on the order of 160 h for the in-plane motion, and 24 h for the out-of-plane motion. Numerical simulation results of the effects of the elevator moving along the cable are presented for different travel velocities and different elevator masses.

  7. Modes for gain maximization of the free electron laser in the low-gain, small-signal regime

    NASA Astrophysics Data System (ADS)

    Moore, Gerald T.

    1986-09-01

    We calculate the maximum gain obtainable from a uniform-wiggler FEL in the small-signal, small-gain regime, taking diffraction into account. The gain and the electron energy detuning at which it is maximal are calculated as a function of the electron-beam Fresnel number F. Gain maximization requires appropriate choice of a resonator. The mirrors need to have larger curvature and aberrations when F is small. In an appendix we generalize our gain formula to a nonuniform wiggler.

  8. The space station tethered elevator system

    NASA Technical Reports Server (NTRS)

    Anderson, Loren A.

    1989-01-01

    The optimized conceptual engineering design of a space station tethered elevator is presented. The elevator is an unmanned mobile structure which operates on a ten kilometer tether spanning the distance between the Space Station and a tethered platform. Elevator capabilities include providing access to residual gravity levels, remote servicing, and transportation to any point along a tether. The potential uses, parameters, and evolution of the spacecraft design are discussed. Engineering development of the tethered elevator is the result of work conducted in the following areas: structural configurations; robotics, drive mechanisms; and power generation and transmission systems. The structural configuration of the elevator is presented. The structure supports, houses, and protects all systems on board the elevator. The implementation of robotics on board the elevator is discussed. Elevator robotics allow for the deployment, retrieval, and manipulation of tethered objects. Robotic manipulators also aid in hooking the elevator on a tether. Critical to the operation of the tethered elevator is the design of its drive mechanisms, which are discussed. Two drivers, located internal to the elevator, propel the vehicle along a tether. These modular components consist of endless toothed belts, shunt-wound motors, regenerative power braking, and computer controlled linear actuators. The designs of self-sufficient power generation and transmission systems are reviewed. Thorough research indicates all components of the elevator will operate under power provided by fuel cells. The fuel cell systems will power the vehicle at seven kilowatts continuously and twelve kilowatts maximally. A set of secondary fuel cells provides redundancy in the unlikely event of a primary system failure. Power storage exists in the form of Nickel-Hydrogen batteries capable of powering the elevator under maximum loads.

  9. Electroactive polymers for gaining sea power

    NASA Astrophysics Data System (ADS)

    Scherber, Benedikt; Grauer, Matthias; Kllnberger, Andreas

    2013-04-01

    Target of this article will be the energy harvesting with dielectric elastomers for wave energy conversion. The main goal of this article is to introduce a new developed material profile enabling a specific amount of energy, making the harvesting process competitive against other existing offshore generation technologies. Electroactive polymers offer the chance to start with small wave energy converters to gain experiences and carry out a similar development as wind energy. Meanwhile there is a consortium being formed in Germany to develop such materials and processes for future products in this new business area. In order to demonstrate the applicability of the technological advancements, a scale demonstrator of a wave energy generator will be developed as well.

  10. Gaining and losing weight in athletics.

    PubMed

    Smith, N J

    1976-07-12

    Participants in many sports, such as wrestling, gymnastics, and light-weight crew, attempt to reduce body weight to achieve a maximum ratio of muscle strength to body weight. Such weight reduction should result only from reduction in excess body fat. In most instances, weight reduction should be achieved at a rate of no more than 1 kg a week, through a modest reduction in diet and a moderate increase in exercise. More rapid weight reduction by starvation and dehydration compromises strength and endurance. Athletes attempting to gain weight should increase weight as muscle mass, not fat. Muscle mass is increased only through muscle work supported by an appropriate increase in food intake. No food, vitamin, drug, or hormone will increase muscle mass. It is recommended that the high caloric diet required to support muscle growth from increased work should be low in animal fats and cholesterol. PMID:947010

  11. Gaining Public Support for RFI Mitigation

    NASA Astrophysics Data System (ADS)

    Finley, D. G.

    2004-05-01

    Astronomy's access to radio spectrum depends to a great extent on international and national regulatory agencies. Such regulation is inherently a political process, so support for radio astronomy by the general public is vital to success. Educating the public about a subject perceived as so highly technical can be challenging. Success in advancing public understanding of the issue and gaining public support is based on two foundations: publicizing the societal value of astronomy; and explaining the interference problem in non-technical terms that draw upon the well-understood terminology of environmental protection. Effective communication can convince non-scientists that astronomical research is a vital and beneficial activity, and that unpolluted access to the radio spectrum is essential to making the new discoveries that are astronomy's contribution to humanity. Convinced of this, the public will support imposing the expense of engineering measures designed to protect radio astronomy, just as they support spending money to protect air, water and soil from pollution.

  12. Neural correlates of weight gain with olanzapine.

    PubMed

    Mathews, Jose; Newcomer, John W; Mathews, Jennifer R; Fales, Christina L; Pierce, Kathy J; Akers, Brandon K; Marcu, Ioana; Barch, Deanna M

    2012-12-01

    CONTEXT Iatrogenic obesity caused by atypical antipsychotics increases the rate of death from all causes. Olanzapine is a commonly prescribed atypical antipsychotic medication that frequently causes weight gain. To our knowledge, the neural correlates of this weight gain have not been adequately studied in humans. OBJECTIVE To test the hypothesis that olanzapine treatment disrupts the neural activity associated with the anticipation and receipt (consumption) of food rewards (chocolate milk and tomato juice). DESIGN Event-related functional magnetic resonance imaging study, before and after a 1-week treatment with olanzapine. SETTING A university neuroimaging center. PARTICIPANTS Twenty-five healthy individuals. MAIN OUTCOME MEASURES Changes in blood oxygen level-dependent activations to the anticipation and receipt of food rewards after olanzapine treatment. RESULTS One week of olanzapine treatment caused significant increases in weight, food consumption, and disinhibited eating. Our imaging data showed enhanced activations in the inferior frontal cortex, striatum, and anterior cingulate cortex to the anticipation of a food reward. Activation in the caudate and putamen were enhanced to the receipt of the rewarding food. We also found a decrease in reward responsivity to receipt of the rewarding food in the lateral orbital frontal cortex, an area of the brain thought to exercise inhibitory control on feeding. CONCLUSIONS Olanzapine treatment enhanced both the anticipatory and consummatory reward responses to food rewards in the brain reward circuitry that is known to respond to food rewards in healthy individuals. We also noted a decrease in responsivity to food consumption in a brain area thought to inhibit feeding behavior. PMID:22868896

  13. Management of Antipsychotic-Related Weight Gain

    PubMed Central

    Maayan, Lawrence; Correll, Christoph U.

    2012-01-01

    Despite variations across individuals and agents, antipsychotics are associated with clearly documented weight gain and adverse metabolic effects. Although increased appetite/caloric intake and various receptors, hormones and peptides have been implicated, biological mechanisms contributing to the increase in weight and glucose and lipid abnormalities with antipsychotics are largely unknown. This has hampered the creation of antipsychotics that are free of cardiometabolic effects, even in antipsychotic-naïve/early-phase patients, as well as the development of strategies that can prevent or drastically diminish the adverse cardiometabolic effects. In general, three strategies can reduce the cardiometabolic risk of antipsychotics: 1) switching to a less orexigenenic/metabolically adverse antipsychotic, 2) adjunctive behavioral treatments and 3) adjunctive pharmacologic interventions. However each of these strategies has only been modestly effective. Among different behavioral interventions (N=14, n=746), group and individual treatment, dietary counseling and cognitive-behavioral therapy seem to be similarly effective. Among 15 different pharmacologic strategies (N=35 , n=1,629), only metformin, fenfluramine, sibutramine, topiramate and reboxetine were more effective than placebo, with the most evidence being available for metformin, yet without any head-to-head trials comparing individual pharmacologic interventions. Even in the most successful trials, however, the risk reduction was modest. Weight was not decreased to a pre-treatment level, and despite superiority compared to placebo, weight gain still often occurred, particularly in antipsychotic-naïve patients and when interventions were “preventively” co-initiated with antipsychotics. Future research should focus on combining treatment modalities or agents and on exploring novel mechanism-based interventions. PMID:20586697

  14. The High Gain Free Electron Lasers.

    NASA Astrophysics Data System (ADS)

    Seo, Yoonho

    This dissertation is composed of two independent parts on a theoretical study of the high gain free electron laser. In the first part (Chapters 2-4) a non-linear (saturation) regime of the free electron lasers (FELs) with electromagnetic wigglers is described. Two opposite configurations for the wiggler field propagation direction are considered in a unified manner. The wiggler field propagating counter to the electron beam is subject to a depletion, and the one propagating parallel to the electron beam is to an amplification. Especially, the latter shows possibility of an explosive instability in a simple mode coupling analysis. A self-consistent set of equations is derived and solved numerically. In the Compton regime the instability saturates at a peak amplitude (eA/m_0c^2)^2 = 0.6(omega_{pb}/ omega_1)^{4/3}(eA_0/m _0c^2)^{1/3}, where A(A_0) is the vector potential of radiation(wiggler) field. In the Raman regime, the FEL instability saturates either by particle trapping or by detuning of the resonance condition due to the nonlinear frequency of the beam mode, depending on the initial wiggler strength. It turns out that these nonlinear saturations set up too early for the system to exhibit any explosive behavior. In the second part (Chapters 5-6) properties of laser field eigenmodes in the linear regime (exponential gain regime) is investigated, including the effect of finite electron beam radius. Existence of such eigenmodes implies the radiation guiding property of an electron beam. For a cold electron beam the eigenmode width is determined with a single parameter which is a ratio of the radiation growth rate to the Rayleigh diffraction rate. Proper scaling for the electron beam temperature and effects of beam bending or shifting is also investigated.

  15. Space elevator systems level analysis

    SciTech Connect

    Laubscher, B. E.

    2004-01-01

    The Space Elevator (SE) represents a major paradigm shift in space access. It involves new, untried technologies in most of its subsystems. Thus the successful construction of the SE requires a significant amount of development, This in turn implies a high level of risk for the SE. This paper will present a systems level analysis of the SE by subdividing its components into their subsystems to determine their level of technological maturity. such a high-risk endeavor is to follow a disciplined approach to the challenges. A systems level analysis informs this process and is the guide to where resources should be applied in the development processes. It is an efficient path that, if followed, minimizes the overall risk of the system's development. systems level analysis is that the overall system is divided naturally into its subsystems, and those subsystems are further subdivided as appropriate for the analysis. By dealing with the complex system in layers, the parameter space of decisions is kept manageable. Moreover, A rational way to manage One key aspect of a resources are not expended capriciously; rather, resources are put toward the biggest challenges and most promising solutions. This overall graded approach is a proven road to success. The analysis includes topics such as nanotube technology, deployment scenario, power beaming technology, ground-based hardware and operations, ribbon maintenance and repair and climber technology.

  16. Defense of a space elevator

    SciTech Connect

    Laubscher, B. E.

    2004-01-01

    The Space Elevator (SE) represents a major paradigm shift in space access. If the SE's promise of low-cost access is to be realized, everything becomes economically more feasible to accomplish in space. In this paper we describe a defensive system of the SE. The primary scenario adopted for this analysis is the SE based on a floating platform in the ocean along the equator. A second possible scenario is the SE stationed on land (island or continent) on or near the equator. The SE will capture the imaginations of people around the world. It will become a symbol of power, capability, wealth and prestige for the country that builds it. As such, it will become a prime terrorist target. Moreover, the tremendous economic leverage afforded by the SE might motivate rogue nations to plot its destruction. Therefore, it is necessary to consider the requirements for defense of the SE. For the purposes of this paper it is assumed that the SE is to be deployed by the United States or one of its companies, and the resources of the US are available for its defense.

  17. Phase-preserved optical elevator

    PubMed Central

    Luo, Yuan; Zhang, Baile; Han, Tiancheng; Chen, Zhi; Duan, Yubo; Chu, Chia-Wei; Barbastathis, George; Qiu, Cheng Wei

    2013-01-01

    The unique superiority of transformation optics devices designed from coordinate transformation is their capability of recovering both ray trajectory and optical path length in light manipulation. However, very few experiments have been done so far to verify this dual-recovery property from viewpoints of both ray trajectory and optical path length simultaneously. The experimental difficulties arise from the fact that most previous optical transformation optics devices only work at the nano-scale; the lack of intercomparison between data from both optical path length and ray trajectory measurement in these experiments obscured the fact that the ray path was subject to a subwavelength lateral shift that was otherwise not easily perceivable and, instead, was pointed out theoretically [B. Zhang et al. Phys. Rev. Lett. 104, 233903, (2010)]. Here, we use a simple macroscopic transformation optics device of phase-preserved optical elevator, which is a typical birefringent optical phenomenon that can virtually lift an optical image by a macroscopic distance, to demonstrate decisively the unique optical path length preservation property of transformation optics. The recovery of ray trajectory is first determined with no lateral shift in the reflected ray. The phase preservation is then verified with incoherent white-light interferometry without ambiguity and phase unwrapping. PMID:23546046

  18. Perinatal Tumor Necrosis Factor-? Production, Influenced by Maternal Pregnancy Weight Gain, Predicts Childhood Asthma

    PubMed Central

    Lohman, I. Carla; Stern, Debra A.; Ellis, Whitney L.; Rothers, Janet; Wright, Anne L.

    2013-01-01

    Rationale: Innate immune responses marked by increases in tumor necrosis factor (TNF)-? have been associated with asthma but whether such alterations are evident before symptoms is not yet clear. Objectives: To determine if prevalence of childhood asthma or asthma-related traits is predicted by perinatal innate immune status and if maternal factors related to pregnancy influence asthma prevalence and innate immune status. Methods: In the Tucson Infant Immune Study (a nonselected birth cohort), presence of eczema and wheezing in the child's first year and physician-diagnosed asthma through age 9 and asthma in the parents was obtained from parent-completed questionnaires. TNF-?, IL-6, IL-10, and IL-12 were measured in supernatants of LPS-stimulated peripheral blood mononuclear cells at birth and 3 months as was TNF-? in plasma. TNF-? single nucleotide polymorphisms were genotyped by Sequenom. Percent predicted FEV1/FVC was measured at age 9. Maternal weight gain during pregnancy and prepregnancy weight were ascertained from medical records. Measurements and Main Results: Infants with persistently elevated LPS-induced TNF-? at birth and 3 months were at increased risk for childhood asthma (odds ratio [OR], 4.1; confidence interval [CI], 1.98.8; n = 233; P = 0.0003) and had decreased FEV1/FVC ratios at age 9. Children with mothers in the top tertile for pregnancy weight gain had increased risk for asthma (OR, 3.4; CI, 1.76.9; n = 225; P = 0.001) and persistently elevated TNF-? in early life (OR, 2.9; CI, 1.48.2; n = 195; P = 0.013). These relations were independent of maternal asthma and rhinitis. Conclusions: Persistently elevated LPS-induced TNF-? production early in life acts as a predictive biomarker for childhood asthma, and excess pregnancy weight gain in the mother seems to contribute to both. PMID:23590270

  19. Antenna Gain Enhancement and Beamshaping using a Diffractive Optical Element (DOE) Lens

    NASA Astrophysics Data System (ADS)

    Torbitt, Christopher

    Dielectric and metamaterial lenses have been designed for gain enhancement and beam shaping. The motivation for this work came from a commercially available slotted waveguide antenna with a dielectric lens that shapes the beam and enhances the gain only in the azimuth plane. When two of these antennas, each with a dielectric lens, are stacked as an array to form the sum and difference patterns the elevation plane gain is low and the beam width too wide to be acceptable for radar applications. The objective of the present work is to design a diffractive optical element (DOE) lens for gain enhancement gain and beam shaping. As compared to other available lenses it is much thinner, lighter and easily machined. The DOE lens is made from rexolite which has a dielectric constant of 2.53. The DOE lens is composed of a series of zones which focus the light at a certain focal length. The phase is the same everywhere on each zone at the focal point. The phase difference between neighboring zones is 2pi, resulting in a constructive interference at the focus. These zones are able to focus the radiation from an antenna in order to enhance the gain and shape the beam. The design parameters include the lens diameter, number of zones, the center zone thickness for a particular frequency and refractive index of the dielectric material. A comprehensive study has been performed in CST Microwave Studio to illustrate the properties of the DOE lens. The focusing property for image formation is verified by a plane wave excitation. Lenses have been designed and tested at different frequencies and with varying design parameters. Gain enhancement and beam shaping are illustrated by modeling the DOE lens in CST and placing it in front of different antennas. This work presents lenses for 10GHz and 40GHz horn antennas, a 3GHz slotted waveguide antenna array, and a 10GHz microstrip patch arrays. Beam shaping and focusing is clearly illustrated for each type of antenna. It is seen that the size of the lens is directly proportional to gain increase which can be as high 20dB enhancement for a 40-GHz horn antenna. The 3GHz DOE lens illustrates for the slotted waveguide array, a gain enhancement of 7dB in the elevation plane, as well as decrease of the 3dB beamwidth from 20° to 13.5°. It is also proved that the DOE lens allows for the creation of a good difference pattern. Experimental validation for the focusing properties and the gain enhancement has been done using the 10GHz DOE, made from rexolite, and fabricated using CNC milling in the RIT Brinkman Lab. The image formation has been verified using an electric field probing station in the Nanoplasmonic lab at RIT. Two types of excitation have been done with a dipole and with a horn antenna, where another dipole probes the field in the transmission plane. The electric field intensity shows clearly the beam focusing by the DOE lens. The X-band anechoic chamber in the Electromagnetics Theory and Application (ETA) lab has been used to demonstrate the gain enhancement of a horn antenna with the fabricated DOE lens. The distance of the lens from the receive antenna has been varied to obtain a maximum received power. The results show a substantial gain enhancement of 6.6 dB for the horn antenna and of 5.6 dB for the patch array.

  20. Robust Gain-Scheduled Fault Tolerant Control for a Transport Aircraft

    NASA Technical Reports Server (NTRS)

    Shin, Jong-Yeob; Gregory, Irene

    2007-01-01

    This paper presents an application of robust gain-scheduled control concepts using a linear parameter-varying (LPV) control synthesis method to design fault tolerant controllers for a civil transport aircraft. To apply the robust LPV control synthesis method, the nonlinear dynamics must be represented by an LPV model, which is developed using the function substitution method over the entire flight envelope. The developed LPV model associated with the aerodynamic coefficient uncertainties represents nonlinear dynamics including those outside the equilibrium manifold. Passive and active fault tolerant controllers (FTC) are designed for the longitudinal dynamics of the Boeing 747-100/200 aircraft in the presence of elevator failure. Both FTC laws are evaluated in the full nonlinear aircraft simulation in the presence of the elevator fault and the results are compared to show pros and cons of each control law.

  1. Focusing on Short-Term Achievement Gains Fails to Produce Long-Term Gains

    ERIC Educational Resources Information Center

    Grissmer, David W.; Ober, David R.; Beekman, John A.

    2014-01-01

    The short-term emphasis engendered by No Child Left Behind (NCLB) has focused research predominantly on unraveling the complexities and uncertainties in assessing short-term results, rather than developing methods and assessing results over the longer term. In this paper we focus on estimating long-term gains and address questions important to

  2. Meta-analysis of the increase in height in maxillary sinus elevations with osteotome

    PubMed Central

    Antonaya-Mira, Roco; Martnez-Rodrguez, Natalia; Cceres-Madroo, Esther; Martnez-Gonzlez, Jos M.

    2012-01-01

    Objectives: To compare the different variations of sinus elevation techniques with osteotomes, to evaluate the increase in height achieved, and to quantify the osseointegration periods and the success rates for the implants placed. Study Design: A meta-analytic study with descriptive statistics was carried out on sinus elevations using osteotomes, analyzing a total of 11 articles published between the years 2003 and 2008. Results: Summers classic technique for performing sinus elevations with osteotomes differs from the current techniques being used with respect to the use of drills, the manner in which the sinus floor is fractured and how the sinus membrane is lifted, and especially on the type of graft usedthe most current tendency being not to use a graft. The maximum gain in height is 4.62 mm, and the minimum gain in height is 2.07 mm, starting with a maximum residual bone height of 8.8 mm and a minimum of 4.1 mm. The osseointegration period is 4.9 months and the success rate is 95.5%. Conclusions: Performing sinus elevations with osteotomes is a predictable technique that enables achieving an increase in bone height and successful results, similar to those of other techniques used, in the placement of implants. Key words:Osteotomes, maxillary sinus elevation, dental implants, osseointegration. PMID:22157659

  3. Active flight increases the gain of visual motion processing in Drosophila.

    PubMed

    Maimon, Gaby; Straw, Andrew D; Dickinson, Michael H

    2010-03-01

    We developed a technique for performing whole-cell patch-clamp recordings from genetically identified neurons in behaving Drosophila. We focused on the properties of visual interneurons during tethered flight, but this technique generalizes to different cell types and behaviors. We found that the peak-to-peak responses of a class of visual motion-processing interneurons, the vertical-system visual neurons (VS cells), doubled when flies were flying compared with when they were at rest. Thus, the gain of the VS cells is not fixed, but is instead behaviorally flexible and changes with locomotor state. Using voltage clamp, we found that the passive membrane resistance of VS cells was reduced during flight, suggesting that the elevated gain was a result of increased synaptic drive from upstream motion-sensitive inputs. The ability to perform patch-clamp recordings in behaving Drosophila promises to help unify the understanding of behavior at the gene, cell and circuit levels. PMID:20154683

  4. Weight Gain, Metabolic Syndrome, and Breast Cancer Recurrence: Are Dietary Recommendations Supported by the Data?

    PubMed Central

    Champ, Colin E.; Volek, Jeff S.; Siglin, Joshua; Jin, Lianjin; Simone, Nicole L.

    2012-01-01

    Metabolic syndrome, which can include weight gain and central obesity, elevated serum insulin and glucose, and insulin resistance, has been strongly associated with breast cancer recurrence and worse outcomes after treatment. Epidemiologic and prospective data do not show conclusive evidence as to which dietary factors may be responsible for these results. Current strategies employ low-fat diets which emphasize supplementing calories with increased intake of fruit, grain, and vegetable carbohydrate sources. Although results thus far have been inconclusive, recent randomized trials employing markedly different dietary strategies in noncancer patients may hold the key to reducing multiple risk factors in metabolic syndrome simultaneously which may prove to increase the long-term outcome of breast cancer patients and decrease recurrences. Since weight gain after breast cancer treatment confers a poor prognosis and may increase recurrence rates, large-scale randomized trials are needed to evaluate appropriate dietary interventions for our breast cancer patients. PMID:23050155

  5. Cholecystokinin elevates mouse plasma lipids.

    PubMed

    Zhou, Lichun; Yang, Hong; Lin, Xinghua; Okoro, Emmanuel U; Guo, Zhongmao

    2012-01-01

    Cholecystokinin (CCK) is a peptide hormone that induces bile release into the intestinal lumen which in turn aids in fat digestion and absorption in the intestine. While excretion of bile acids and cholesterol into the feces eliminates cholesterol from the body, this report examined the effect of CCK on increasing plasma cholesterol and triglycerides in mice. Our data demonstrated that intravenous injection of [Thr28, Nle31]-CCK at a dose of 50 ng/kg significantly increased plasma triglyceride and cholesterol levels by 22 and 31%, respectively, in fasting low-density lipoprotein receptor knockout (LDLR(-/-)) mice. The same dose of [Thr28, Nle31]-CCK induced 6 and 13% increases in plasma triglyceride and cholesterol, respectively, in wild-type mice. However, these particular before and after CCK treatment values did not achieve statistical significance. Oral feeding of olive oil further elevated plasma triglycerides, but did not alter plasma cholesterol levels in CCK-treated mice. The increased plasma cholesterol in CCK-treated mice was distributed in very-low, low and high density lipoproteins (VLDL, LDL and HDL) with less of an increase in HDL. Correspondingly, the plasma apolipoprotein (apo) B48, B100, apoE and apoAI levels were significantly higher in the CCK-treated mice than in untreated control mice. Ligation of the bile duct, blocking CCK receptors with proglumide or inhibition of Niemann-Pick C1 Like 1 transporter with ezetimibe reduced the hypercholesterolemic effect of [Thr28, Nle31]-CCK in LDLR(-/-) mice. These findings suggest that CCK-increased plasma cholesterol and triglycerides as a result of the reabsorption of biliary lipids from the intestine. PMID:23300532

  6. Modeling Root Exudation, Priming and Protection in Soil Carbon Responses to Elevated CO2 from Ecosystem to Global Scales

    NASA Astrophysics Data System (ADS)

    Sulman, B. N.; Phillips, R.; Shevliakova, E.; Oishi, A. C.; Pacala, S. W.

    2014-12-01

    The sensitivity of soil organic carbon (SOC) to changing environmental conditions represents a critical uncertainty in coupled carbon cycle-climate models. Much of this uncertainty arises from our limited understanding of the extent to which plants induce SOC losses (through accelerated decomposition or "priming") or promote SOC gains (via stabilization through physico-chemical protection). We developed a new SOC model, "Carbon, Organisms, Rhizosphere and Protection in the Soil Environment" (CORPSE), to examine the net effect of priming and protection in response to rising atmospheric CO2, and conducted simulations of rhizosphere priming effects at both ecosystem and global scales. At the ecosystem scale, the model successfully captured and explained disparate SOC responses at the Duke and Oak Ridge free-air CO2 enrichment (FACE) experiments. We show that stabilization of "new" carbon in protected SOC pools may equal or exceed microbial priming of "old" SOC in ecosystems with readily decomposable litter (e.g. Oak Ridge). In contrast, carbon losses owing to priming dominate the net SOC response in ecosystems with more resistant litters (e.g. Duke). For global simulations, the model was fully integrated into the Geophysical Fluid Dynamics Laboratory (GFDL) land model LM3. Globally, priming effects driven by enhanced root exudation and expansion of the rhizosphere reduced SOC storage in the majority of terrestrial areas, partially counterbalancing SOC gains from the enhanced ecosystem productivity driven by CO2 fertilization. Collectively, our results suggest that SOC stocks globally depend not only on temperature and moisture, but also on vegetation responses to environmental changes, and that protected C may provide an important constraint on priming effects.

  7. Biological Determinants Linking Infant Weight Gain and Child Obesity: Current Knowledge and Future Directions12

    PubMed Central

    Young, Bridget E.; Johnson, Susan L.; Krebs, Nancy F.

    2012-01-01

    Childhood obesity rates have reached epidemic proportions. Excessive weight gain in infancy is associated with persistence of elevated weight status and later obesity. In this review, we make the case that weight gain in the first 6 mo is especially predictive of later obesity risk due to the metabolic programming that can occur early postpartum. The current state of knowledge regarding the biological determinants of excess infant weight gain is reviewed, with particular focus on infant feeding choice. Potential mechanisms by which different feeding approaches may program the metabolic profile of the infant, causing the link between early weight gain and later obesity are proposed. These mechanisms are likely highly complex and involve synergistic interactions between endocrine effects and factors that alter the inflammatory and oxidative stress status of the infant. Gaps in current knowledge are highlighted. These include a lack of data describing 1) what type of infant body fat distribution may impart risk and 2) how maternal metabolic dysfunction (obesity and/or diabetes) may affect milk composition and exert downstream effects on infant metabolism. Improved understanding and management of these early postnatal determinants of childhood obesity may have great impact on reducing its prevalence. PMID:22983846

  8. Antipsychotic-Induced Insulin Resistance and Postprandial Hormonal Dysregulation Independent of Weight Gain or Psychiatric Disease

    PubMed Central

    Teff, Karen L.; Rickels, Michael R.; Grudziak, Joanna; Fuller, Carissa; Nguyen, Huong-Lan; Rickels, Karl

    2013-01-01

    Atypical antipsychotic (AAP) medications that have revolutionized the treatment of mental illness have become stigmatized by metabolic side effects, including obesity and diabetes. It remains controversial whether the defects are treatment induced or disease related. Although the mechanisms underlying these metabolic defects are not understood, it is assumed that the initiating pathophysiology is weight gain, secondary to centrally mediated increases in appetite. To determine if the AAPs have detrimental metabolic effects independent of weight gain or psychiatric disease, we administered olanzapine, aripiprazole, or placebo for 9 days to healthy subjects (n = 10, each group) under controlled in-patient conditions while maintaining activity levels. Prior to and after the interventions, we conducted a meal challenge and a euglycemic-hyperinsulinemic clamp to evaluate insulin sensitivity and glucose disposal. We found that olanzapine, an AAP highly associated with weight gain, causes significant elevations in postprandial insulin, glucagon-like peptide 1 (GLP-1), and glucagon coincident with insulin resistance compared with placebo. Aripiprazole, an AAP considered metabolically sparing, induces insulin resistance but has no effect on postprandial hormones. Importantly, the metabolic changes occur in the absence of weight gain, increases in food intake and hunger, or psychiatric disease, suggesting that AAPs exert direct effects on tissues independent of mechanisms regulating eating behavior. PMID:23835329

  9. DSN 70-meter antenna X- and S-band calibration. Part 1: Gain measurements

    NASA Technical Reports Server (NTRS)

    Richter, P. H.; Slobin, S. D.

    1989-01-01

    Aperture efficiency measurements made during 1988 on the three 70-m stations (DSS-14, DSS-43, and DSS-63) at X-band (8420 MHz) and S-band (2295 MHz) have been analyzed and reduced to yield best estimates of antenna gain versus elevation. The analysis has been carried out by fitting the gain data to a theoretical expression based on the Ruze formula. Newly derived flux density and source-size correction factors for the natural radio calibration sources used in the measurements have been used in the reduction of the data. Peak gains measured at the three stations were 74.18 (plus or minus 0.10) dBi at X-band, and 63.34 (plus or minus 0.03) dBi at S-band, with corresponding peak aperture efficiencies of 0.687 (plus or minus 0.015) and 0.762 (plus or minus 0.006), respectively. The values quoted assume no atmosphere is present, and the estimated absolute accuracy of the gain measurements is approximately plus or minus 0.2 dB at X-band and plus or minus 0.1 dB at S-band (1-sigma values).

  10. Contribution of the hypothalamus and gut to weight gain susceptibility and resistance in mice.

    PubMed

    Fam, Barbara C; Sgambellone, Rebecca; Ruan, Zheng; Proietto, Joseph; Andrikopoulos, Sofianos

    2015-06-01

    Obesity susceptibility in humans and in rodent strains varies in response to the consumption of high-energy density (HED) diets. However, the exact mechanism(s) involved in this susceptibility remain(s) unresolved. The aim of the present study was to gain greater insight into this susceptibility by using C57BL/6J (B6) mice that were separated into obesity-prone (diet-induced obese (DIO)) and obesity-resistant (diet-induced resistant (DR)) groups following an HED diet for 6 weeks. Physiological, biochemical and gene expression assessments of energy balance were performed in the DIO and DR mice on an HED diet and chow-fed mice. The increased weight gain of the DIO mice as compared to the DR mice was associated with increased energy intake and higher plasma leptin and adiponectin levels but not with reduced physical activity or resting energy expenditure. Hypothalamic Pomc gene expression was elevated, but there were no changes in Npy or Agrp expression. Adipose tissue leptin and adiponectin gene expression were significantly reduced in the DIO group as compared to the DR group. Interestingly, ileum expression of G protein-coupled receptor (Gpr) 40 (Gpr40) was significantly increased, whereas Gpr120, Gpr119, Gpr41, and glucagon-like peptide 1 (Glp1) were reduced. Contrastingly, the lower weight gain of the DR group was associated with elevated adipose tissue leptin and adiponectin gene expression, but there were no differences in plasma hormone or hypothalamic gene expression levels as compared to chow-fed mice. Therefore, the present data demonstrate that susceptibility and resistance to diet-induced weight gain in B6 mice appears to be predominantly driven by peripheral rather than hypothalamic modifications, and changes in gut-specific receptors are a potentially important contributor to this variation. PMID:25934705

  11. Dual AMP features variable gain and high bandwidth

    NASA Astrophysics Data System (ADS)

    Pfund, George; Zhang, Jim; Wu, Jieh-Tsorng

    1992-02-01

    Variable-gain amplifiers (VGAs) are important components in many receiver systems. One such VGA design intended for lightwave transmission systems operating at gigabit-per-second rates provides 2.5-GHz bandwidth and 40-dB gain.

  12. Infant Weight Gain Linked to Possible Type 1 Diabetes Risk

    MedlinePLUS

    ... 156085.html Infant Weight Gain Linked to Possible Type 1 Diabetes Risk But study author says it's too soon ... of life to a possible higher risk of type 1 diabetes. The mean weight gain during the first year ...

  13. National requirements for improved elevation data

    USGS Publications Warehouse

    Snyder, Gregory I.; Sugarbaker, Larry J.; Jason, Allyson L.; Maune, David F.

    2014-01-01

    This report presents the results of surveys, structured interviews, and workshops conducted to identify key national requirements for improved elevation data for the United States and its territories, including coastlines. Organizations also identified and reported the expected economic benefits that would be realized if their requirements for improved elevation were met (appendixes 1–3). This report describes the data collection methodology and summarizes the findings. Participating organizations included 34 Federal agencies, 50 States and two territories, and a sampling of local governments, tribes, and nongovernmental orgnizations. The nongovernmental organizations included The Nature Conservancy and a sampling of private sector businesses. These data were collected in 2010-2011 as part of the National Enhanced Elevation Assessment (NEEA), a study to identify program alternatives for better meeting the Nation’s elevation data needs. NEEA tasks included the collection of national elevation requirements; analysis of the benefits and costs of meeting these requirements; assessment of emerging elevation technologies, lifecycle data management needs, and costs for managing and distributing a national-scale dataset and derived products; and candidate national elevation program alternatives that balance costs and benefits in meeting the Nation’s elevation requirements. The NEEA was sponsored by the National Digital Elevation Program (NDEP), a government coordination body with the U.S. Geological Survey (USGS) as managing partner that includes the National Geospatial-Intelligence Agency (NGA), the Federal Emergency Management Agency (FEMA), the Natural Resources Conservation Service (NRCS), the U.S. Army Corps of Engineers (USACE), and the National Oceanic and Atmospheric Administration (NOAA), among the more than a dozen agencies and organizations. The term enhanced elevation data as used in this report refers broadly to three-dimensional measurements of land or submerged topography, built features, vegetation structure, and other landscape detail. Additional information about NEEA and its later use in the development of a 3D Elevation Program (3DEP) can be found at http://nationalmap.gov/3DEP/index.html.

  14. Typical Mid Tower Elevation & Section, Typical Mid Tower Footing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Typical Mid Tower Elevation & Section, Typical Mid Tower Footing Section & Elevation, South Tower Section & Elevation, and North Tower Sections & Elevation - Cape Arago Light Station Footbridge, Gregory Point, Charleston, Coos County, OR

  15. GD SDR Automatic Gain Control Characterization Testing

    NASA Technical Reports Server (NTRS)

    Nappier, Jennifer M.; Briones, Janette C.

    2013-01-01

    The General Dynamics (GD) S-Band software defined radio (SDR) in the Space Communications and Navigation (SCAN) Testbed on the International Space Station (ISS) will provide experimenters an opportunity to develop and demonstrate experimental waveforms in space. The GD SDR platform and initial waveform were characterized on the ground before launch and the data will be compared to the data that will be collected during on-orbit operations. A desired function of the SDR is to estimate the received signal to noise ratio (SNR), which would enable experimenters to better determine on-orbit link conditions. The GD SDR does not have an SNR estimator, but it does have an analog and a digital automatic gain control (AGC). The AGCs can be used to estimate the SDR input power which can be converted into a SNR. Tests were conducted to characterize the AGC response to changes in SDR input power and temperature. This purpose of this paper is to describe the tests that were conducted, discuss the results showi ng how the AGCs relate to the SDR input power, and provide recommendations for AGC testing and characterization.

  16. GD SDR Automatic Gain Control Characterization Testing

    NASA Technical Reports Server (NTRS)

    Nappier, Jennifer M.; Briones, Janette C.

    2013-01-01

    The General Dynamics (GD) S-Band software defined radio (SDR) in the Space Communications and Navigation (SCAN) Testbed on the International Space Station (ISS) will provide experimenters an opportunity to develop and demonstrate experimental waveforms in space. The GD SDR platform and initial waveform were characterized on the ground before launch and the data will be compared to the data that will be collected during on-orbit operations. A desired function of the SDR is to estimate the received signal to noise ratio (SNR), which would enable experimenters to better determine on-orbit link conditions. The GD SDR does not have an SNR estimator, but it does have an analog and a digital automatic gain control (AGC). The AGCs can be used to estimate the SDR input power which can be converted into a SNR. Tests were conducted to characterize the AGC response to changes in SDR input power and temperature. This purpose of this paper is to describe the tests that were conducted, discuss the results showing how the AGCs relate to the SDR input power, and provide recommendations for AGC testing and characterization.

  17. Progress toward high-gain laser fusion

    SciTech Connect

    Storm, E.

    1988-09-28

    A 1985-1986 Review of the US inertial confinement fusion program by the National Academy of Sciences concluded that five more years might be required to obtain enough data to determine the future course of the program. Since then, data from the Nova laser and from the Halite/Centurion program have resolved most of the outstanding problems identified by the NAS review. In particular, we now believe that we can produce a sufficiently uniform target; that we can keep the energy content in hot electrons and high-energy photons low enough (/approximately/1--10% of drive energy, depending on target design) and achieve enough pulse-shaping accuracy (/approximately/10%, with a dynamic range of 100:1) to keep the fuel on a near-Fermi-degenerate adiabat; that we can produce an /approximately/100-Mbar pressure pulse of sufficient uniformity (/approximately/1%), and can we control hydrodynamic instabilities so that the mix of the pusher into the hot spot is low enough to permit marginal ignition. These results are sufficiently encouraging that the US Department of Energy is planning to complete a 10-MJ laboratory microfusion facility to demonstrate high-gain ICF in the laboratory within a decade. 22 refs., 1 fig.

  18. Progress toward high-gain laser fusion

    NASA Astrophysics Data System (ADS)

    Storm, Erik

    1988-09-01

    A 1985 to 1986 Review of the U.S. inertial confinement fusion program by the National Academy of Sciences concluded that five more years might be required to obtain enough data to determine the future course of the program. Since then, data from the Nova laser and from the Halite/Centurion program have resolved most of the outstanding problems identified by the NAS review. In particular, we now believe that we can produce a sufficiently uniform target; that we can keep the energy content in hot electrons and high-energy photons low enough (approximately 1 to 10 percent of drive energy, depending on target design) and achieve enough pulse-shaping accuracy (approximately 10 percent, with a dynamic range of 100:1) to keep the fuel on a near-Fermi-degenerate adiabat; that we can produce an approximately 100-Mbar pressure pulse of sufficient uniformity (approximately 1 percent), and can control hydrodynamic instabilities so that the mix of the pusher into the hot spot is low enough to permit marginal ignition. These results are sufficiently encouraging that DOE is planning to complete a 10-MJ laboratory microfusion facility to demonstrate high-gain ICF in the laboratory within a decade.

  19. Proprioceptive feedback determines visuomotor gain in Drosophila.

    PubMed

    Bartussek, Jan; Lehmann, Fritz-Olaf

    2016-01-01

    Multisensory integration is a prerequisite for effective locomotor control in most animals. Especially, the impressive aerial performance of insects relies on rapid and precise integration of multiple sensory modalities that provide feedback on different time scales. In flies, continuous visual signalling from the compound eyes is fused with phasic proprioceptive feedback to ensure precise neural activation of wing steering muscles (WSM) within narrow temporal phase bands of the stroke cycle. This phase-locked activation relies on mechanoreceptors distributed over wings and gyroscopic halteres. Here we investigate visual steering performance of tethered flying fruit flies with reduced haltere and wing feedback signalling. Using a flight simulator, we evaluated visual object fixation behaviour, optomotor altitude control and saccadic escape reflexes. The behavioural assays show an antagonistic effect of wing and haltere signalling on visuomotor gain during flight. Compared with controls, suppression of haltere feedback attenuates while suppression of wing feedback enhances the animal's wing steering range. Our results suggest that the generation of motor commands owing to visual perception is dynamically controlled by proprioception. We outline a potential physiological mechanism based on the biomechanical properties of WSM and sensory integration processes at the level of motoneurons. Collectively, the findings contribute to our general understanding how moving animals integrate sensory information with dynamically changing temporal structure. PMID:26909184

  20. Proprioceptive feedback determines visuomotor gain in Drosophila

    PubMed Central

    Bartussek, Jan; Lehmann, Fritz-Olaf

    2016-01-01

    Multisensory integration is a prerequisite for effective locomotor control in most animals. Especially, the impressive aerial performance of insects relies on rapid and precise integration of multiple sensory modalities that provide feedback on different time scales. In flies, continuous visual signalling from the compound eyes is fused with phasic proprioceptive feedback to ensure precise neural activation of wing steering muscles (WSM) within narrow temporal phase bands of the stroke cycle. This phase-locked activation relies on mechanoreceptors distributed over wings and gyroscopic halteres. Here we investigate visual steering performance of tethered flying fruit flies with reduced haltere and wing feedback signalling. Using a flight simulator, we evaluated visual object fixation behaviour, optomotor altitude control and saccadic escape reflexes. The behavioural assays show an antagonistic effect of wing and haltere signalling on visuomotor gain during flight. Compared with controls, suppression of haltere feedback attenuates while suppression of wing feedback enhances the animal’s wing steering range. Our results suggest that the generation of motor commands owing to visual perception is dynamically controlled by proprioception. We outline a potential physiological mechanism based on the biomechanical properties of WSM and sensory integration processes at the level of motoneurons. Collectively, the findings contribute to our general understanding how moving animals integrate sensory information with dynamically changing temporal structure. PMID:26909184

  1. Assessment of learning gains in a flipped biochemistry classroom.

    PubMed

    Ojennus, Deanna Dahlke

    2016-01-01

    The flipped classroom has become an increasingly popular pedagogical approach to teaching and learning. In this study, learning gains were assessed in a flipped biochemistry course and compared to gains in a traditional lecture. Although measured learning gains were not significantly different between the two courses, student perception of learning gains did differ and indicates a higher level of satisfaction with the flipped lecture format. 2015 by The International Union of Biochemistry and Molecular Biology, 44:20-27, 2016. PMID:26593859

  2. Assessment of Learning Gains in a Flipped Biochemistry Classroom

    ERIC Educational Resources Information Center

    Ojennus, Deanna Dahlke

    2016-01-01

    The flipped classroom has become an increasingly popular pedagogical approach to teaching and learning. In this study, learning gains were assessed in a flipped biochemistry course and compared to gains in a traditional lecture. Although measured learning gains were not significantly different between the two courses, student perception of…

  3. Problems with IQ Gains: The Huge Vocabulary Gap

    ERIC Educational Resources Information Center

    Flynn, James R.

    2010-01-01

    Despite Kaufman, Raven's Progressive Matrices and the Wechsler subtest Similarities are tests whose gains call for special explanation. The spread of "scientific spectacles" is the key, but its explanatory potential has been exhausted. Three trends force us to look elsewhere: (a) gains on Wechsler subtests such as Picture Arrangement, (b) gains in…

  4. 20 CFR 220.141 - Substantial gainful activity, defined.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) Substantial work activity. Substantial work activity is work activity that involves doing significant physical... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Substantial gainful activity, defined. 220... RETIREMENT ACT DETERMINING DISABILITY Substantial Gainful Activity § 220.141 Substantial gainful...

  5. 20 CFR 416.910 - Meaning of substantial gainful activity.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Meaning of substantial gainful activity. 416....910 Meaning of substantial gainful activity. Substantial gainful activity means work that— (a) Involves doing significant and productive physical or mental duties; and (b) Is done (or intended) for...

  6. 26 CFR 7.105-2 - Substantial gainful activity.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 14 2011-04-01 2010-04-01 true Substantial gainful activity. 7.105-2 Section 7... activity. (a) Purpose. This section defines substantial gainful activity for purposes of section 105(d) and... substantial gainful activity, and provides examples of the application of the definition and rules in...

  7. 20 CFR 416.910 - Meaning of substantial gainful activity.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Meaning of substantial gainful activity. 416....910 Meaning of substantial gainful activity. Substantial gainful activity means work that— (a) Involves doing significant and productive physical or mental duties; and (b) Is done (or intended) for...

  8. 20 CFR 220.141 - Substantial gainful activity, defined.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...) Substantial work activity. Substantial work activity is work activity that involves doing significant physical... 20 Employees' Benefits 1 2011-04-01 2011-04-01 false Substantial gainful activity, defined. 220... RETIREMENT ACT DETERMINING DISABILITY Substantial Gainful Activity § 220.141 Substantial gainful...

  9. 26 CFR 7.105-2 - Substantial gainful activity.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 14 2010-04-01 2010-04-01 false Substantial gainful activity. 7.105-2 Section 7... activity. (a) Purpose. This section defines substantial gainful activity for purposes of section 105(d) and... substantial gainful activity, and provides examples of the application of the definition and rules in...

  10. Assessment of Learning Gains in a Flipped Biochemistry Classroom

    ERIC Educational Resources Information Center

    Ojennus, Deanna Dahlke

    2016-01-01

    The flipped classroom has become an increasingly popular pedagogical approach to teaching and learning. In this study, learning gains were assessed in a flipped biochemistry course and compared to gains in a traditional lecture. Although measured learning gains were not significantly different between the two courses, student perception of

  11. 24 CFR 3280.506 - Heat loss/heat gain.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 5 2014-04-01 2014-04-01 false Heat loss/heat gain. 3280.506... URBAN DEVELOPMENT MANUFACTURED HOME CONSTRUCTION AND SAFETY STANDARDS Thermal Protection § 3280.506 Heat loss/heat gain. The manufactured home heat loss/heat gain shall be determined by methods outlined...

  12. 24 CFR 3280.506 - Heat loss/heat gain.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 5 2012-04-01 2012-04-01 false Heat loss/heat gain. 3280.506... URBAN DEVELOPMENT MANUFACTURED HOME CONSTRUCTION AND SAFETY STANDARDS Thermal Protection § 3280.506 Heat loss/heat gain. The manufactured home heat loss/heat gain shall be determined by methods outlined...

  13. 24 CFR 3280.506 - Heat loss/heat gain.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Heat loss/heat gain. 3280.506... URBAN DEVELOPMENT MANUFACTURED HOME CONSTRUCTION AND SAFETY STANDARDS Thermal Protection § 3280.506 Heat loss/heat gain. The manufactured home heat loss/heat gain shall be determined by methods outlined...

  14. 24 CFR 3280.506 - Heat loss/heat gain.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 5 2011-04-01 2011-04-01 false Heat loss/heat gain. 3280.506... URBAN DEVELOPMENT MANUFACTURED HOME CONSTRUCTION AND SAFETY STANDARDS Thermal Protection § 3280.506 Heat loss/heat gain. The manufactured home heat loss/heat gain shall be determined by methods outlined...

  15. 24 CFR 3280.506 - Heat loss/heat gain.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 5 2013-04-01 2013-04-01 false Heat loss/heat gain. 3280.506... URBAN DEVELOPMENT MANUFACTURED HOME CONSTRUCTION AND SAFETY STANDARDS Thermal Protection § 3280.506 Heat loss/heat gain. The manufactured home heat loss/heat gain shall be determined by methods outlined...

  16. Changes in wetland sediment elevation following major storms: implications for estimating trends in relative sea-level rise

    USGS Publications Warehouse

    Cahoon, D.R.

    2003-01-01

    Hurricanes can be important agents of geomorphic change in coastal marshes and mangrove forests. Hurricanes can cause large-scale redistribution of sediments within the coastal environment resulting in sedimentation, erosion, disruption of vegetated substrates, or some combination of these processes in coastal wetlands. It has been proposed that such sediment pulsing events are important at maintaining wetland sediment elevations in sediment-poor settings with high rates of relative sea-level rise, such as the Mississippi River Delta. But do these pulsing events result in a net gain in sediment elevation even when substantial amounts of sediment are deposited? Clearly sediment erosion and scour would result in a loss of elevation. But will a substantial sediment deposit on poorly consolidated sediments always result in a net gain in elevation? If the wetland vegetation is killed by wind, tidal surge, or the introduction of saline water, will there be a collapse of sediment elevation in the absence of root production and ongoing decomposition of root matter? During the past decade several wetlands where my colleagues and I have monitored sedimentation and elevation change have been struck by one to several hurricanes. This paper describes the range of sediment elevation responses to hurricane strikes, the suggested mechanisms driving those responses, the implications for estimating long-term trends in relative sea-level rise, and future research needs for improving our understanding of the role that major storms play in wetland sediment elevation dynamics. For many wetlands the change in sediment elevation was directly proportional to the amount of sediment deposited by the storm. But surprisingly, there was a loss of elevation in some wetlands with substantial sediment deposits. In these wetlands, the impact of the storm was either direct (sedimentation and compaction) or indirect (vegetation death), and the effect on sediment elevation was either permanent or temporary. For example, 2 cm of sediment deposited by Hurricane Andrew on a healthy salt marsh in south Louisiana had a direct and positive effect on sediment elevation. But in a deteriorated salt marsh a 3 cm thick sediment deposit was associated with a permanent loss in elevation (we have monitored this site for 10 years). The apparent mechanism driving elevation loss was compaction of the weakened substrate by the weight of the sediment deposit, the storm surge waters, or both. Clearly, storm-related sediment pulses are not going to save this marsh from becoming submerged by rising sea level. A temporary loss in elevation, as much as 2 cm, was observed in a North Carolina salt marsh with a highly organic substrate after each of 3 successive hurricanes even when sediment was deposited. The loss in elevation was apparently related to degassing of the chronically flooded substrate while the rebound in elevation was apparently related to a temporary drawdown of marsh water levels. Interestingly, sediment elevation increased after Hurricane Dennis in 1999, although the increase was less than the thickness of the sediment deposit. Further research is required to determine the mechanisms driving storm-related elevation change (i.e., compaction and expansion) in this marsh. There were two marshes where the gain in sediment elevation was greater than the thickness of the sediment deposit, but the effect was short-lived. In a high salt marsh in southern California, we hypothesize that the temporary spike in elevation was related to the flushing of salts from the hypersaline soils, which enhanced root growth that led to an increase in elevation. In a marsh with a highly organic substrate in north Florida, temporary increases in elevation (as much as 2 cm) greater than the thickness of the sediment deposit were apparently related to groundwater fluxes, which may have been influenced by enhanced runoff from storm rainfall. Lastly, Hurricane Mitch

  17. 75 FR 61371 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-05

    ....; Reorganization Plan No. 3 of 1978, 3 CFR, 1978 Comp., p. 329; E.O. 12127, 44 FR 19367, 3 CFR, 1979 Comp., p. 376... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations AGENCY... proposed Base (1% annual-chance) Flood Elevations (BFEs) and proposed BFE modifications for the...

  18. 75 FR 67310 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-02

    ....; Reorganization Plan No. 3 of 1978, 3 CFR, 1978 Comp., p. 329; E.O. 12127, 44 FR 19367, 3 CFR, 1979 Comp., p. 376... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations AGENCY... proposed Base (1% annual-chance) Flood Elevations (BFEs) and proposed BFE modifications for the...

  19. [Spiked helmet sign ST-segment elevation].

    PubMed

    Tomcsnyi, Jnos; Frsz, Tams

    2013-01-27

    The authors report the spiked helmet ST-segment elevation in two patients in order to draw attention to this high-risk electrocardiographic sign. This form of ST-segment elevation needs an urgent evaluation and management of the critically ill patient. PMID:23335725

  20. 75 FR 31342 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-03

    ...Comments are requested on the proposed Base (1% annual-chance) Flood Elevations (BFEs) and proposed BFE modifications for the communities listed in the table below. The purpose of this notice is to seek general information and comment regarding the proposed regulatory flood elevations for the reach described by the downstream and upstream locations in the table below. The BFEs and modified......

  1. 75 FR 59184 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-27

    ....; Reorganization Plan No. 3 of 1978, 3 CFR, 1978 Comp., p. 329; E.O. 12127, 44 FR 19367, 3 CFR, 1979 Comp., p. 376... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations AGENCY... proposed Base (1% annual-chance) Flood Elevations (BFEs) and proposed BFE modifications for the...

  2. 75 FR 43479 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-26

    ....; Reorganization Plan No. 3 of 1978, 3 CFR, 1978 Comp., p. 329; E.O. 12127, 44 FR 19367, 3 CFR, 1979 Comp., p. 376... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations AGENCY... proposed Base (1% annual-chance) Flood Elevations (BFEs) and proposed BFE modifications for the...

  3. 76 FR 66887 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-28

    ....; Reorganization Plan No. 3 of 1978, 3 CFR, 1978 Comp., p. 329; E.O. 12127, 44 FR 19367, 3 CFR, 1979 Comp., p. 376... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations AGENCY... proposed Base (1% annual-chance) Flood Elevations (BFEs) and proposed BFE modifications for the...

  4. 77 FR 22551 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-16

    ... rule published at 72 FR 68784, in the December 6, 2007, issue of the Federal Register, FEMA published a... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations AGENCY...) publishes proposed determinations of Base (1% annual-chance) Flood Elevations (BFEs) and modified BFEs...

  5. 75 FR 59188 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-27

    ....; Reorganization Plan No. 3 of 1978, 3 CFR, 1978 Comp., p. 329; E.O. 12127, 44 FR 19367, 3 CFR, 1979 Comp., p. 376... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations AGENCY... proposed Base (1% annual-chance) Flood Elevations (BFEs) and proposed BFE modifications for the...

  6. 76 FR 40670 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-11

    ... et seq.; Reorganization Plan No. 3 of 1978, 3 CFR, 1978 Comp., p. 329; E.O. 12127, 44 FR 19367, 3 CFR... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations AGENCY... proposed Base (1% annual-chance) Flood Elevations (BFEs) and proposed BFE modifications for the...

  7. 75 FR 5909 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-05

    ..., 1978 Comp., p. 329; E.O. 12127, 44 FR 19367, 3 CFR, 1979 Comp., p. 376. Sec. 67.4 2. The tables... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations AGENCY... proposed Base (1% annual-chance) Flood Elevations (BFEs) and proposed BFE modifications for the...

  8. 75 FR 5929 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-05

    ... published on September 8, 2009, at 74 FR 46047. The table for Carroll County, Arkansas, and Incorporated... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations AGENCY...% annual-chance) Flood Elevations (BFEs) and modified BFEs for communities participating in the...

  9. 75 FR 59192 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-27

    ....; Reorganization Plan No. 3 of 1978, 3 CFR, 1978 Comp., p. 329; E.O. 12127, 44 FR 19367, 3 CFR, 1979 Comp., p. 376... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations AGENCY... proposed Base (1% annual-chance) Flood Elevations (BFEs) and proposed BFE modifications for the...

  10. 76 FR 19005 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-06

    ....; Reorganization Plan No. 3 of 1978, 3 CFR, 1978 Comp., p. 329; E.O. 12127, 44 FR 19367, 3 CFR, 1979 Comp., p. 376... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations AGENCY... proposed Base (1% annual-chance) Flood Elevations (BFEs) and proposed BFE modifications for the...

  11. 75 FR 59181 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-27

    ....; Reorganization Plan No. 3 of 1978, 3 CFR, 1978 Comp., p. 329; E.O. 12127, 44 FR 19367, 3 CFR, 1979 Comp., p. 376... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations AGENCY... proposed Base (1% annual-chance) Flood Elevations (BFEs) and proposed BFE modifications for the...

  12. 75 FR 34415 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-17

    ..., 1978 Comp., p. 329; E.O. 12127, 44 FR 19367, 3 CFR, 1979 Comp., p. 376. Sec. 67.4 2. The tables... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations AGENCY... proposed Base (1% annual-chance) Flood Elevations (BFEs) and proposed BFE modifications for the...

  13. 76 FR 43968 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-22

    ....; Reorganization Plan No. 3 of 1978, 3 CFR, 1978 Comp., p. 329; E.O. 12127, 44 FR 19367, 3 CFR, 1979 Comp., p. 376... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations AGENCY... proposed Base (1% annual-chance) Flood Elevations (BFEs) and proposed BFE modifications for the...

  14. 76 FR 3590 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-20

    ...Comments are requested on the proposed Base (1% annual-chance) Flood Elevations (BFEs) and proposed BFE modifications for the communities listed in the table below. The purpose of this notice is to seek general information and comment regarding the proposed regulatory flood elevations for the reach described by the downstream and upstream locations in the table below. The BFEs and modified......

  15. 75 FR 31377 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-03

    ...Comments are requested on the proposed Base (1% annual-chance) Flood Elevations (BFEs) and proposed BFE modifications for the communities listed in the table below. The purpose of this notice is to seek general information and comment regarding the proposed regulatory flood elevations for the reach described by the downstream and upstream locations in the table below. The BFEs and modified......

  16. 76 FR 36482 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-22

    ...Comments are requested on the proposed Base (1% annual-chance) Flood Elevations (BFEs) and proposed BFE modifications for the communities listed in the table below. The purpose of this proposed rule is to seek general information and comment regarding the proposed regulatory flood elevations for the reach described by the downstream and upstream locations in the table below. The BFEs and......

  17. 75 FR 68744 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-09

    ...Comments are requested on the proposed Base (1% annual-chance) Flood Elevations (BFEs) and proposed BFE modifications for the communities listed in the table below. The purpose of this notice is to seek general information and comment regarding the proposed regulatory flood elevations for the reach described by the downstream and upstream locations in the table below. The BFEs and modified......

  18. 24. 'HANGAR SHEDS ELEVATIONS DETAILS; ARCHITECTURAL PLANS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    24. 'HANGAR SHEDS - ELEVATIONS - DETAILS; ARCHITECTURAL PLANS - PLANT AREA; MODIFICATION CENTER NO. 1, DAGGETT, CALIFORNIA.' Partial elevations, and details of sliding doors and ventilator flaps, as built. Contract no. W509 Eng. 2743; File no. 555/81, revision B, dated April 6, 1943. No sheet number. - Barstow-Daggett Airport, Hangar Shed No. 4, 39500 National Trails Highway, Daggett, San Bernardino County, CA

  19. Insect Population Dynamics in Commercial Grain Elevators

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Data were collected in 1998-2002 from wheat stored in commercial grain elevators in south-central Kansas. Storage bins at these elevators had concrete walls and were typically 6-9 m in diameter and 30-35 m tall. A vacuum-probe sampler was used to collect ten 3-kg grain samples in the top 12 m of the...

  20. 78 FR 21273 - Final Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-10

    ... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Final Flood Elevation Determinations AGENCY... (FEMA) makes the final determinations listed below for the modified BFEs for each community listed... Act. As flood elevation determinations are not within the scope of the Regulatory Flexibility Act, 5...

  1. 78 FR 21272 - Final Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-10

    ... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Final Flood Elevation Determinations AGENCY... (FEMA) makes the final determinations listed below for the modified BFEs for each community listed... Act. As flood elevation determinations are not within the scope of the Regulatory Flexibility Act, 5...

  2. 77 FR 15664 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-16

    ...On August 3, 2011, FEMA published in the Federal Register a proposed rule that contained an erroneous table. This notice provides corrections to that table, to be used in lieu of the information published at 76 FR 46701. The table provided here represents the flooding sources, location of referenced elevations, and effective and modified elevations for the City of Cadiz, Kentucky.......

  3. A Space Elevator Based Exploration Strategy

    NASA Astrophysics Data System (ADS)

    Edwards, Bradley C.

    2004-02-01

    Technological advances and recent studies have laid the groundwork for eventual construction of a space elevator. Within 15 years an operational space elevator could be running from Earth to beyond geosynchronous. The basic mechanical operation allows for low operational cost ($250/kg), high capacity (>13tons, >5tons/day/elevator), a range of destinations (LEO, GEO, Moon, Mars, Asteroids, and Venus), and minimal launch forces. The low risk operation of the space elevator would allow large scale robotic and human exploration of the solar system. An operational elevator will immediately move primary interest from LEO to GEO for many activities and open commercial space activities such as solar power satellite arrays for beaming power to Earth. Robotic exploration to all destinations would be able to use larger, fixed structures, more massive platforms and be launched for a fraction of current costs. Human exploration could start at GEO for maintaining commercial assets, and enhanced Earth-observing systems and then step to Mars where a receiving elevator could also be established. This paper will cover the basics of a space elevator and a comprehensive strategy for human and exploratory use of space based on the space elevator.

  4. 75 FR 19328 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-14

    ...Comments are requested on the proposed Base (1% annual-chance) Flood Elevations (BFEs) and proposed BFE modifications for the communities listed in the table below. The purpose of this document is to seek general information and comment regarding the proposed regulatory flood elevations for the reach described by the downstream and upstream locations in the table below. The BFEs and modified......

  5. 75 FR 29296 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-25

    ..., 1978 Comp., p. 329; E.O. 12127, 44 FR 19367, 3 CFR, 1979 Comp., p. 376. Sec. 67.4 2. The tables... Communities affected elevation Elevation in meters (MSL) Effective Modified Fairbanks-North Star Borough... Fairbanks-North Star River and Chena River. River levee and south of Borough. Mitchell Expressway from...

  6. 76 FR 70386 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-14

    ....; Reorganization Plan No. 3 of 1978, 3 CFR, 1978 Comp., p. 329; E.O. 12127, 44 FR 19367, 3 CFR, 1979 Comp., p. 376... affected elevation ** Elevation in meters (MSL) Effective Modified Montgomery County, Alabama, and... City of Kingsford, downstream of Little Township of Breitung. Quinnesec Dam. At the Iron County...

  7. Elevated Ozone Alters Soybean-Virus Interaction

    Technology Transfer Automated Retrieval System (TEKTRAN)

    We examine the effects of elevated O3 and elevated CO2, two major components of global change, on the interaction between soybean and Soybean Mosaic Virus (SMV) by measuring molecular, cellular, and physiological processes, in natural field conditions and in controlled environment. In natural field ...

  8. Photosynthetic responses to understory shade and elevated carbon dioxide concentration in four northern hardwood tree species.

    PubMed

    Sefcik, Lesley T; Zak, Donald R; Ellsworth, David S

    2006-12-01

    Seedling responses to elevated atmospheric CO(2) concentration ([CO(2)]) and solar irradiance were measured over two growing seasons in shade-tolerant Acer saccharum Marsh. and Fagus grandifolia J.F. Ehrh. and shade-intolerant Prunus serotina, a J.F. Ehrh. and Betula papyrifera Marsh. Seedlings were exposed to a factorial combination of [CO2] (ambient and elevated (658 micromol mol-1)) and understory shade (deep and moderate) in open-top chambers placed in a forest understory. The elevated [CO(2)] treatment increased mean light-saturated net photosynthetic rate by 63% in the shade-tolerant species and 67% in the shade-intolerant species. However, when measured at the elevated [CO(2)], long-term enhancement of photosynthesis was 10% lower than the instantaneous enhancement seen in ambient-[CO(2)]-grown plants (P < 0.021). Overall, growth light environment affected long-term photosynthetic enhancement by elevated [CO(2)]: as the growth irradiance increased, proportional enhancement due to elevated [CO(2)] decreased from 97% for plants grown in deep shade to 47% for plants grown in moderate shade. Results suggest that in N-limited northern temperate forests, trees grown in deep shade may display greater photosynthetic gains from a CO(2)-enriched atmosphere than trees growing in more moderate shade, because of greater downregulation in the latter environment. If photosynthetic gains by deep-shade-grown plants in response to elevated [CO(2)] translate into improved growth and survival of shade-intolerant species, it could alter the future composition and dynamics of successional forest communities. PMID:17169898

  9. EROSION OF ELEVATED TEMPERATURE CORROSION SCALES ON METALS

    SciTech Connect

    Maasberg, J.A.; Levy, A.V.

    1981-05-01

    Combined erosion-corrosion poses a considerable problem to the design of long lifetime metallic components in energy conversion systems. To gain some insight into this problem, scales were formed on stainless steel at elevated temperature and subsequently were eroded at room temperature to determine the nature of the erosion rates and the mechanism of scale removal. Thin corrosion scales were formed on 310 stainless steel and an experimental Fe-18Cr-5Al-1Hf alloy at high temperatures (9ooo and 980C) in gas mixtures with various levels of oxygen and combined oxygen-sulfur. The corroded specimens were eroded at room temperature in an air-solid particle stream using 50{micro}m SiC at 60 ms{sup -1}. The conditions of the corrosive exposures, the rates of erosion of these scales and the microscopic appearance of the eroded surface were correlated to determine the mechanism of thin scale erosion.

  10. North Elevation: LowLift Pumping Station (East) 2008; West Elevation and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    North Elevation: Low-Lift Pumping Station (East) 2008; West Elevation and Floor Plan: Outbuilding - Robert B. Morse Water Filtration Plant, 10700 and 10701 Columbia Pike, Silver Spring, Montgomery County, MD

  11. Intracavity gain shaping in millijoule-level, high gain Ho:YLF regenerative amplifiers.

    PubMed

    Murari, Krishna; Cankaya, Huseyin; Kroetz, Peter; Cirmi, Giovanni; Li, Peng; Ruehl, Axel; Hartl, Ingmar; Kärtner, Franz X

    2016-03-15

    We demonstrate intracavity gain shaping inside a 2 μm Ho:YLF regenerative amplifier with a spectral bandwidth of 2.9 nm broadened to 5.4 nm, corresponding to Fourier-limited pulses of 1 ps duration. The intracavity gain shaping is achieved by using a simple etalon, which acts as a frequency-selective filter. The output of the regenerative amplifier is amplified by a single-pass amplifier, and we achieve total energy of 2.2 mJ and pulse duration of 2.4 ps at 1 kHz with pulse fluctuations <1%. The amplifier chain is seeded by a home-built mode-locked holmium-doped fiber oscillator. PMID:26977647

  12. Gain-phase grating based on spatial modulation of active Raman gain in cold atoms

    SciTech Connect

    Kuang Shangqi; Jin Chunshui; Li Chun

    2011-09-15

    In order to obtain an atomic grating which can diffract light into the high-order directions more efficiently, a gain-phase grating (GPG) based on the spatial modulation of active Raman gain is theoretically presented. This grating is induced by a pump field and a standing wave in ultracold atoms, and it not only diffracts a weak probe field propagating along a direction normal to the standing wave into the high-order directions, but also amplifies the amplitude of the zero-order diffraction. In contrast with electromagnetically induced grating or electromagnetically induced phase grating, the GPG has larger diffraction efficiencies in the high-order directions. Hence it is more suitable to be utilized as an all-optical router in optical networking and communication.

  13. Measurement of the absolute gas gain and gain variations study in straw-tube detectors

    NASA Astrophysics Data System (ADS)

    Gianotti, P.; Kashchuk, A.; Levitskaya, O.; Passamonti, L.; Pierluigi, D.; Russo, A.; Savri, M.

    2013-08-01

    We present the results of the absolute gas gain measurement of a straw drift-tube filled with a binary gaseous mixture Ar-CO2(90-10) at 2 bar absolute pressure. The measurement has been performed using an intense 1.3 GBq 137Cs-source producing the primary ionization current. The results, as a function of the high voltage and gas parameters, were fitted and parameterized with a Diethorn's formula.

  14. Are videogame training gains specific or general?

    PubMed Central

    Patterson, Michael D.

    2014-01-01

    Many recent studies using healthy adults document enhancements in perception and cognition from playing commercial action videogames (AVGs). Playing action games (e.g., Call of Duty, Medal of Honor) is associated with improved bottom-up lower-level information processing skills like visual-perceptual and attentional processes. One proposal states a general improvement in the ability to interpret and gather statistical information to predict future actions which then leads to better performance across different perceptual/attentional tasks. Another proposal claims all the tasks are separately trained in the AVGs because the AVGs and laboratory tasks contain similar demands. We review studies of action and non-AVGs to show support for the latter proposal. To explain transfer in AVGs, we argue that the perceptual and attention tasks share common demands with the trained videogames (e.g., multiple object tracking (MOT), rapid attentional switches, and peripheral vision). In non-AVGs, several studies also demonstrate specific, limited transfer. One instance of specific transfer is the specific enhancement to mental rotation after training in games with a spatial emphasis (e.g., Tetris). In contrast, the evidence for transfer is equivocal where the game and task do not share common demands (e.g., executive functioning). Thus, the “common demands” hypothesis of transfer not only characterizes transfer effects in AVGs, but also non-action games. Furthermore, such a theory provides specific predictions, which can help in the selection of games to train human cognition as well as in the design of videogames purposed for human cognitive and perceptual enhancement. Finally this hypothesis is consistent with the cognitive training literature where most post-training gains are for tasks similar to the training rather than general, non-specific improvements. PMID:24782722

  15. Are videogame training gains specific or general?

    PubMed

    Oei, Adam C; Patterson, Michael D

    2014-01-01

    Many recent studies using healthy adults document enhancements in perception and cognition from playing commercial action videogames (AVGs). Playing action games (e.g., Call of Duty, Medal of Honor) is associated with improved bottom-up lower-level information processing skills like visual-perceptual and attentional processes. One proposal states a general improvement in the ability to interpret and gather statistical information to predict future actions which then leads to better performance across different perceptual/attentional tasks. Another proposal claims all the tasks are separately trained in the AVGs because the AVGs and laboratory tasks contain similar demands. We review studies of action and non-AVGs to show support for the latter proposal. To explain transfer in AVGs, we argue that the perceptual and attention tasks share common demands with the trained videogames (e.g., multiple object tracking (MOT), rapid attentional switches, and peripheral vision). In non-AVGs, several studies also demonstrate specific, limited transfer. One instance of specific transfer is the specific enhancement to mental rotation after training in games with a spatial emphasis (e.g., Tetris). In contrast, the evidence for transfer is equivocal where the game and task do not share common demands (e.g., executive functioning). Thus, the "common demands" hypothesis of transfer not only characterizes transfer effects in AVGs, but also non-action games. Furthermore, such a theory provides specific predictions, which can help in the selection of games to train human cognition as well as in the design of videogames purposed for human cognitive and perceptual enhancement. Finally this hypothesis is consistent with the cognitive training literature where most post-training gains are for tasks similar to the training rather than general, non-specific improvements. PMID:24782722

  16. Loss restlessness and gain calmness: durable effects of losses and gains on choice switching.

    PubMed

    Yechiam, Eldad; Zahavi, Gal; Arditi, Eli

    2015-08-01

    While the traditional conceptualization of the effect of losses focuses on bias in the subjective weight of losses compared with respective gains, some accounts suggest more global task-related effects of losses. Based on a recent attentional theory, we predicted a positive after-effect of losses on choice switching in later tasks. In two experimental studies, we found increased choice switching rates in tasks with losses compared to tasks with no losses. Additionally, this heightened shifting behavior was maintained in subsequent tasks that do not include losses, a phenomenon we refer to as "loss restlessness." Conversely, gains were found to have an opposite "calming" effect on choice switching. Surprisingly, the loss restlessness phenomenon was observed following an all-losses payoff regime but not after a task with symmetric mixed gains and losses. This suggests that the unresolved mental account following an all-losses regime increases search behavior. Potential implications to macro level phenomena, such as the leverage effect, are discussed. PMID:25348826

  17. Gaseous N fluxes in Mediterranean catchments: from low elevation chaparral to high elevation subalpine ecosystems

    NASA Astrophysics Data System (ADS)

    Homyak, P. M.; Sickman, J. O.

    2010-12-01

    Recent studies on gaseous N emissions from soils in semiarid ecosystems have highlighted the importance of these losses for terrestrial ecosystems. Losses tend to be relatively large during seasonal transitions where soil rewetting results in a “hot moment” of increased biological nitrification and gaseous N flux. To gain better understanding of chaparral N-dynamics, we measured NO and N2O emissions for one year in a chamise-dominated watershed located in the foothills of the Sierra Nevada (California) whose previous nitrogen budget suggested net N retention (i.e., N inputs from atmospheric deposition > hydrologic outputs). We are also making additional gas flux measurements along an elevational gradient (300 to 2800 m) to determine if NO and N2O fluxes vary across ecosystems (chaparral, mixed conifer, and subalpine) with varying capacity for assimilation of N deposition. Gaseous N fluxes measured at the chaparral site through the one-year period are in agreement with other studies of semiarid ecosystems showing a pulse of NO (as high as 100 ng N m-2 s-1) immediately after rewetting of dry soils. The hot moment decreases by about half 24-hours after rewetting and decreases in magnitude with increasing frequency of rewetting episodes during the winter rainy season. As with other studies in semiarid ecosystems, NO emissions decreased significantly with decreases in temperature averaging about 0.03 ng N m-2 s-1 and sometimes becoming negative during the cool winter. Measurements of the magnitude of the hot moment along the altitudinal gradient are in progress, and to the best of our knowledge, will be the first field measurement to include nitric oxide fluxes in subalpine ecosystems. Based on our current data, it is clear that gaseous N fluxes are an important component in N budgets for ecosystems experiencing a strong seasonal transition in soil physico-chemical conditions.

  18. Prenatal Organochlorine Compound Exposure, Rapid Weight Gain, and Overweight in Infancy

    PubMed Central

    Mendez, Michelle A.; Garcia-Esteban, Raquel; Guxens, Mónica; Vrijheid, Martine; Kogevinas, Manolis; Goñi, Fernando; Fochs, Silvia; Sunyer, Jordi

    2011-01-01

    Background Although it has been hypothesized that fetal exposure to endocrine-disrupting chemicals may increase obesity risk, empirical data are limited, and it is uncertain how early in life any effects may begin. Objectives We explored whether prenatal exposure to several organochlorine compounds (OCs) is associated with rapid growth in the first 6 months of life and body mass index (BMI) later in infancy. Methods Data come from the INMA (Infancia y Medio-Ambiente) Child and Environment birth cohort in Spain, which recruited 657 women in early pregnancy. Rapid growth during the first 6 months was defined as a change in weight-for-age z-scores > 0.67, and elevated BMI at 14 months, as a z-score ≥ the 85th percentile. Generalized linear models were used to estimate the risk of rapid growth or elevated BMI associated with 2,2-bis(p-chlorophenyl)-1,1-dichloroethylene (DDE), hexachlorobenzene, β-hexachlorohexane, and polychlorinated biphenyls in first-trimester maternal serum. Results After multivariable adjustment including other OCs, DDE exposure above the first quartile was associated with doubling of the risk of rapid growth among children of normal-weight (BMI < 25 kg/m2), but not overweight, mothers. DDE was also associated with elevated BMI at 14 months (relative risk per unit increase in log DDE = 1.50; 95% confidence interval, 1.11–2.03). Other OCs were not associated with rapid growth or elevated BMI after adjustment. Conclusions In this study we found prenatal DDE exposure to be associated with rapid weight gain in the first 6 months and elevated BMI later in infancy, among infants of normal-weight mothers. More research exploring the potential role of chemical exposures in early-onset obesity is needed. PMID:20923745

  19. A Psychometric Assessment of the GAIN General Individual Severity Scale (GAIN-GISS) and Short Screeners (GAIN-SS) Among Adolescents in Outpatient Treatment Programs

    PubMed Central

    Stucky, Brian D.; Edelen, Maria Orlando; Ramchand, Rajeev

    2013-01-01

    The Global Appraisal of Individual Needs (GAIN) - General Individual Severity Scale (GAIN-GISS), and GAIN-Short Screener (GAIN-SS) are widely used diagnostic measures of internalizing disorders, externalizing disorders, substance abuse, and criminal and violent behavior. Though prevalent in clinical and research settings, there is only limited psychometric evidence of the dimensional structure of these scales. Our investigation used intake data from 6,909 adolescents presenting to outpatient substance abuse treatment facilities in the United States. Our analytic approach used exploratory and item factor analyses to evaluate the underlying factor structure. Multi- and unidimensional item response theory models were employed to evaluate the utility of the scales at providing precise score estimates at various locations of severity. Most scales were confirmed as unidimensional; scales with evidence of multidimensionality, identified as having a weak general dimension and strong specific dimensions using a bifactor IRT model, include the Crime Violence Scale and the GAIN-SS. PMID:23994048

  20. Etiology and therapeutic approach to elevated lactate

    PubMed Central

    Andersen, Lars W.; Mackenhauer, Julie; Roberts, Jonathan C.; Berg, Katherine M.; Cocchi, Michael N.; Donnino, Michael W.

    2014-01-01

    Lactate levels are commonly evaluated in acutely ill patients. Although most commonly used in the context of evaluating shock, lactate can be elevated for many reasons. While tissue hypoperfusion is probably the most common cause of elevation, many other etiologies or contributing factors exist. Clinicians need to be aware of the many potential causes of lactate elevation as the clinical and prognostic importance of an elevated lactate varies widely by disease state. Moreover, specific therapy may need to be tailored to the underlying cause of elevation. The current review is based on a comprehensive PubMed search and contains an overview of the pathophysiology of lactate elevation followed by an in-depth look at the varied etiologies, including medication-related causes. The strengths and weaknesses of lactate as a diagnostic/prognostic tool and its potential use as a clinical endpoint of resuscitation will be discussed. The review ends with some general recommendations on management of patients with elevated lactate. PMID:24079682

  1. Origin of the highly elevated Pyrenean peneplain

    NASA Astrophysics Data System (ADS)

    Babault, Julien; van den Driessche, Jean; Bonnet, StPhane; Castelltort, SBastien; Crave, Alain

    2005-04-01

    Peneplanation of mountain ranges is generally considered the result of long-term erosional processes that smooth relief and lower elevation near sea level. Therefore peneplain remnants at high elevation in mountain ranges are used to infer posttectonic surface uplift. Such an interpretation has been proposed for the Pyrenees where high-elevation, low-relief erosional surfaces rose up to more than 2000 m. Because the Pyrenean foreland basins are filled with very thick continental deposits, which have buried the early jagged landscape, we challenge this hypothesis by pointing out that relief applanation does not necessarily require elevation lowering. We propose an alternative interpretation in which piedmont aggradation of detrital sediment that comes from erosion of the high chain induces the rise of the base level of the range, therefore reducing strongly the erosive efficiency of the drainage system and resulting in the progressive smoothing of the relief. Such a process allows a high-elevation, low-relief erosional surface to develop at the scale of the range. In the Pyrenees, occurrence of high-elevation, low-relief erosional surface remnants does not imply a posttectonic uplift, but is instead due to the dissection of the initial Miocene high-elevation, low-relief surface by the recent drainage system, the erosive activity of which has been enhanced by global climate change from the late Pliocene onward.

  2. Sea level and turbidity controls on mangrove soil surface elevation change

    USGS Publications Warehouse

    2014-01-01

    Increases in sea level are a threat to seaward fringing mangrove forests if levels of inundation exceed the physiological tolerance of the trees; however, tidal wetlands can keep pace with sea level rise if soil surface elevations can increase at the same pace as sea level rise. Sediment accretion on the soil surface and belowground production of roots are proposed to increase with increasing sea level, enabling intertidal habitats to maintain their position relative to mean sea level, but there are few tests of these predictions in mangrove forests. Here we used variation in sea level and the availability of sediments caused by seasonal and inter-annual variation in the intensity of La Nina-El Nino to assess the effects of increasing sea level on surface elevation gains and contributing processes (accretion on the surface, subsidence and root growth) in mangrove forests. We found that soil surface elevation increased with mean sea level (which varied over 250mm during the study) and with turbidity at sites where fine sediment in the water column is abundant. In contrast, where sediments were sandy, rates of surface elevation gain were high, but not significantly related to variation in turbidity, and were likely to be influenced by other factors that deliver sand to the mangrove forest. Root growth was not linked to soil surface elevation gains, although it was associated with reduced shallow subsidence, and therefore may contribute to the capacity of mangroves to keep pace with sea level rise. Our results indicate both surface (sedimentation) and subsurface (root growth) processes can influence mangrove capacity to keep pace with sea level rise within the same geographic location, and that current models of tidal marsh responses to sea level rise capture the major feature of the response of mangroves where fine, but not coarse, sediments are abundant.

  3. Sea level and turbidity controls on mangrove soil surface elevation change

    NASA Astrophysics Data System (ADS)

    Lovelock, Catherine E.; Adame, Maria Fernanda; Bennion, Vicki; Hayes, Matthew; Reef, Ruth; Santini, Nadia; Cahoon, Donald R.

    2015-02-01

    Increases in sea level are a threat to seaward fringing mangrove forests if levels of inundation exceed the physiological tolerance of the trees; however, tidal wetlands can keep pace with sea level rise if soil surface elevations can increase at the same pace as sea level rise. Sediment accretion on the soil surface and belowground production of roots are proposed to increase with increasing sea level, enabling intertidal habitats to maintain their position relative to mean sea level, but there are few tests of these predictions in mangrove forests. Here we used variation in sea level and the availability of sediments caused by seasonal and inter-annual variation in the intensity of La Nina-El Nino to assess the effects of increasing sea level on surface elevation gains and contributing processes (accretion on the surface, subsidence and root growth) in mangrove forests. We found that soil surface elevation increased with mean sea level (which varied over 250 mm during the study) and with turbidity at sites where fine sediment in the water column is abundant. In contrast, where sediments were sandy, rates of surface elevation gain were high, but not significantly related to variation in turbidity, and were likely to be influenced by other factors that deliver sand to the mangrove forest. Root growth was not linked to soil surface elevation gains, although it was associated with reduced shallow subsidence, and therefore may contribute to the capacity of mangroves to keep pace with sea level rise. Our results indicate both surface (sedimentation) and subsurface (root growth) processes can influence mangrove capacity to keep pace with sea level rise within the same geographic location, and that current models of tidal marsh responses to sea level rise capture the major feature of the response of mangroves where fine, but not coarse, sediments are abundant.

  4. Evaluation of Experimental Data from the Gains Balloon GPS Surface Reflection Instrument

    NASA Technical Reports Server (NTRS)

    Ganoe, George G.; Johnson, Thomas A.; Somero, John Ryan

    2002-01-01

    The GPS Surface Reflection Instrument was integrated as an experiment on the GAINS (Global Airocean IN-situ System) 48-hour balloon mission flown in June 2002. The data collected by similar instruments in the past has been used to measure sea state from which ocean surface winds can be accurately estimated. The GPS signal has also been shown to be reflected from wetland areas and even from subsurface moisture. The current version of the instrument has been redesigned to be more compact, use less power, and withstand a greater variation in environmental conditions than previous versions. This instrument has also incorporated a new data collection mode to track 5 direct satellites (providing a continuous navigation solution) and multiplex the remaining 7 channels to track the reflected signal of the satellite tracked in channel 0. The new software mode has been shown to increase the signal to noise ratio of the collected data and enhance the science return of the instrument. During the GAINS balloon flight over the Northwest US, the instrument measured surface reflections as they were detected over the balloon's ground track. Since ground surface elevations in this area vary widely from the WGS-84 ellipsoid altitude, the instrument software has been modified to incorporate a surface altitude correction based on USGS 30-minute Digital Elevation Models. Information presented will include facts about instrument design goals, data collection methodologies and algorithms, and will focus on results of the science data analyses for the mission.

  5. US GeoData Digital Elevation Models

    USGS Publications Warehouse

    U.S. Geological Survey

    2000-01-01

    Digital elevation model (DEM) data are arrays of regularly spaced elevation values referenced horizontally either to a Universal Transverse Mercator (UTM) projection or to a geographic coordinate system. The grid cells are spaced at regular intervals along south to north profiles that are ordered from west to east. The U.S. Geological Survey (USGS) produces five primary types of elevation data: 7.5-minute DEM, 30-minute DEM, 1-degree DEM, 7.5-minute Alaska DEM, and 15-minute Alaska DEM.

  6. US GeoData digital elevation models

    USGS Publications Warehouse

    U.S. Geological Survey

    1997-01-01

    Digital elevation model (DEM) data consist of a sampled array of regularly spaced elevation values referenced horizontally either to a Universal Transverse Mercator (UTM) projection or to a geographic coordinate system. The grid cells are spaced at regular intervals along south to north profiles that are ordered from west to east. the U.S> Geological Survey (USGS) produces five primary types of elevation data: 7.5-minute DEM, 30-minute DEM, 1-degree DEM, 7.5-minute Alaska DEM, and 15-minute Alaska DEM.

  7. Training children in pedestrian safety: distinguishing gains in knowledge from gains in safe behavior.

    PubMed

    Schwebel, David C; McClure, Leslie A

    2014-06-01

    Pedestrian injuries contribute greatly to child morbidity and mortality. Recent evidence suggests that training within virtual pedestrian environments may improve children's street crossing skills, but may not convey knowledge about safety in street environments. We hypothesized that (a) children will gain pedestrian safety knowledge via videos/software/internet websites, but not when trained by virtual pedestrian environment or other strategies; (b) pedestrian safety knowledge will be associated with safe pedestrian behavior both before and after training; and (c) increases in knowledge will be associated with increases in safe behavior among children trained individually at streetside locations, but not those trained by means of other strategies. We analyzed data from a randomized controlled trial evaluating pedestrian safety training. We randomly assigned 240 children ages 7-8 to one of four training conditions: videos/software/internet, virtual reality (VR), individualized streetside instruction, or a no-contact control. Both virtual and field simulations of street crossing at 2-lane bi-directional mid-block locations assessed pedestrian behavior at baseline, post-training, and 6-month follow-up. Pedestrian knowledge was assessed orally on all three occasions. Children trained by videos/software/internet, and those trained individually, showed increased knowledge following training relative to children in the other groups (ps<0.01). Correlations between pedestrian safety knowledge and pedestrian behavior were mostly non-significant. Correlations between change in knowledge and change in behavior from pre- to post-intervention also were non-significant, both for the full sample and within conditions. Children trained using videos/software/internet gained knowledge but did not change their behavior. Children trained individually gained in both knowledge and safer behavior. Children trained virtually gained in safer behavior but not knowledge. If VR is used for training, tools like videos/internet might effectively supplement training. We discovered few associations between knowledge and behavior, and none between changes in knowledge and behavior. Pedestrian safety knowledge and safe pedestrian behavior may be orthogonal constructs that should be considered independently for research and training purposes. PMID:24573688

  8. Impact of the Teacher Advancement Program on Student Test Score Gains: Findings from an Independent Appraisal. Working Paper 2008-19

    ERIC Educational Resources Information Center

    Springer, Matthew G.; Ballou, Dale; Peng, Art

    2008-01-01

    This article presents findings from the first independent, third-party appraisal on the impact of the Teacher Advancement Program (TAP) on student test score gains in mathematics. TAP is a comprehensive school reform model designed to attract highly-effective teachers, improve instructional effectiveness, and elevate student achievement. We use a…

  9. Measuring Elevation in a Threatened Wetland, CA

    USGS Multimedia Gallery

    A USGS employee uses an instrument to measure the elevation at Seal Beach National Wildlife Refuge in southern California, in contribution to a study on sea level rise's impact on coastal wetlands....

  10. 3D Elevation Program: summary for Nebraska

    USGS Publications Warehouse

    Carswell, William J., Jr.

    2015-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  11. 3D Elevation Program: summary for Vermont

    USGS Publications Warehouse

    Carswell, William J., Jr.

    2015-01-01

    The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.

  12. The Expanding Burden of Elevated Blood Pressure in China: Evidence From Jiangxi Province, 20072010

    PubMed Central

    Xu, Gang; Liu, Junxiu; Liu, Shiwei; Zhou, Haiming; Orekoya, Olubunmi; Liu, Jie; Li, Yichong; Tang, Ji; Zhou, Chunlian; Huang, Jiuling

    2015-01-01

    Abstract Elevated blood pressure (BP) as a risk factor accounts for the biggest burden of disease worldwide and in China. This study aimed to estimate attributed mortality and life expectancy (LE) to elevated BP in Jiangxi province between 2007 and 2010. BP and mortality data (2007 and 2010 inclusive) were obtained from the National Chronic Diseases and Risk Factors Surveillance Survey and Disease Surveillance Points system, respectively. Population-attributable fraction used in comparative risk assessment of the Global Burden of Disease study 2010 were followed to quantify the attributed mortality to elevated BP, subsequently life table methods were applied to estimate its effects on LE. Uncertainty analysis was conducted to get 95% uncertainty intervals (95% uncertainty interval [UI]) for each outcome. There are 35,482 (95% UI: 31,38939,928) and 47,842 (42,32353,837) deaths in Jiangxi province were caused by elevated BP in 2007 and 2010, respectively. 2.24 (1.872.65) years of LE would be gained if all the attributed deaths were eliminated in 2007, and increased to 3.04 (2.523.48) in 2010. If the mean value of elevated BP in 2010 was decreased by 5 and 10?mm Hg, 5324 (47105991) and 11,422 (10,10412,853) deaths would be avoided, with 0.41 (0.370.48) and 0.85 (0.711.09) years of LE gained, respectively. The deaths attributable to elevated BP in Jiangxi province has increased by 35% from 2007 to 2010, with 0.8 years of LE loss, suggesting the necessity to take actions to control BP in Chinese population. PMID:26426647

  13. Elevated blood pressure in offspring of rats exposed to diverse chemicals during pregnancy.

    PubMed

    Rogers, John M; Ellis-Hutchings, Robert G; Grey, Brian E; Zucker, Robert M; Norwood, Joel; Grace, Curtis E; Gordon, Christopher J; Lau, Christopher

    2014-02-01

    Adverse intrauterine environments have been associated with increased risk of later cardiovascular disease and hypertension. In an animal model using diverse developmental toxicants, we measured blood pressure (BP), renal nephron endowment, renal glucocorticoid receptor (GR) gene expression, and serum aldosterone in offspring of pregnant Sprague Dawley rats exposed to dexamethasone (Dex), perfluorooctane sulfonate (PFOS), atrazine, perfluorononanoic acid (PFNA), arsenic, or nicotine. BP was assessed by tail cuff photoplethysmography, nephron endowment by confocal microscopy, and renal GR mRNA by qPCR. BP was also measured by telemetry, and corticosterone (CORT) was measured in resting or restrained Dex and atrazine offspring. Treated dams gained less weight during treatment in all groups except arsenic. There were chemical- and sex-specific effects on birth weight, but offspring body weights were similar by weaning. BP was higher in Dex, PFOS, atrazine, and PFNA male offspring by 7-10 weeks. Female offspring exhibited elevated BP at 10 weeks for PFNA and arsenic, and at 37 weeks for Dex, PFOS, and atrazine. Dex, PFOS, and atrazine offspring still exhibited elevated BP at 52-65 weeks of age; others did not. Elevated BP was associated with lower nephron counts. Dex, PFOS, and atrazine offspring had elevated renal GR gene expression. Elevations in BP were also observed in Dex and atrazine offspring by radiotelemetry. Atrazine offspring exhibited enhanced CORT response to restraint. Elevated offspring BP was induced by maternal exposure to toxicants. Because all treatments affected maternal gestational weight gain, maternal stress may be a common underlying factor in these observations. PMID:24218149

  14. Elevator Illusion and Gaze Direction in Hypergravity

    NASA Technical Reports Server (NTRS)

    Cohen, Malcolm M.; Hargens, Alan (Technical Monitor)

    1995-01-01

    A luminous visual target in a dark hypergravity (Gz greater than 1) environment appears to be elevated above its true physical position. This "elevator illusion" has been attributed to changes in oculomotor control caused by increased stimulation of the otolith organs. Data relating the magnitude of the illusion to the magnitude of the changes in oculomotor control have been lacking. The present study provides such data.

  15. Weight gain following breast cancer diagnosis: Implication and proposed mechanisms

    PubMed Central

    Makari-Judson, Grace; Braun, Barry; Jerry, D Joseph; Mertens, Wilson C

    2014-01-01

    Weight gain occurs in the majority of women following breast cancer treatment. An overview of studies describing weight gain amongst women treated with early to modern chemotherapy regimens is included. Populations at higher risk include women who are younger, closer to ideal body weight and who have been treated with chemotherapy. Weight gain ranges between 1 to 5 kg, and may be associated with change in body composition with gain in fat mass and loss in lean body mass. Women are unlikely to return to pre-diagnosis weight. Possible mechanisms including inactivity and metabolic changes are explored. Potential interventions are reviewed including exercise, dietary changes and pharmacologic agents. Although breast cancer prognosis does not appear to be significantly impacted, weight gain has negative consequences on quality of life and overall health. Future studies should explore change in body composition, metabolism and insulin resistance. Avoiding weight gain in breast cancer survivors following initial diagnosis and treatment should be encouraged. PMID:25114844

  16. Who Gains? Genetic and Neurophysiological Correlates of BMI Gain Upon College Entry in Women

    PubMed Central

    Bauer, Lance O.

    2014-01-01

    The present investigation examined P3 event-related electroencephalographic potentials and a short and selected list of addiction-related candidate gene single nucleotide polymorphisms (SNPs) within 84 female students, aged 18–20 yrs. The students were assigned to groups defined by the presence versus absence of a positive body mass index (BMI) change from the pre-college physical exam to the current day. Analyses revealed significantly greater P3 latencies and reduced P3 amplitudes during a response inhibition task among students who exhibited a BMI gain. BMI gain was also significantly associated with a ANKK1 SNP previously implicated in substance dependence risk. In logistic regression analyses, P3 latencies at the frontal electrode and this ANKK1 genotype correctly classified 71.1% of the students into the BMI groups. The present findings suggest that heritable indicators of impaired response inhibition can differentiate students who may be on a path toward an overweight or obese body mass. PMID:25049133

  17. Energy considerations in the partial space elevator

    NASA Astrophysics Data System (ADS)

    Woo, Pamela; Misra, Arun K.

    2014-06-01

    The space elevator has been proposed as an alternate method for space transportation. A partial elevator is composed of a tether of several hundreds of kilometres, held vertically in tension between two end masses, with its centre of orbit placed at the geosynchronous orbit. A spacecraft can dock at the lower end, and then use the climber on the elevator to ascend to higher altitudes. In this paper, energy calculations are performed, to determine whether a partial elevator can provide sufficient savings in operational costs, compared to the traditional rocket-powered launch. The energy required to launch a spacecraft from a Low Earth Orbit (LEO) to the geostationary orbit (GEO) is calculated for two trajectories. In the first trajectory, the spacecraft travels from LEO to GEO via a Hohmann transfer. In the second trajectory, the spacecraft travels from LEO to the lower end of the partial space elevator with a Hohmann transfer, and then uses the elevator to climb to GEO. The total energy required is compared between the two trajectories. The effects of tether length, spacecraft-to-climber mass ratio, altitude of LEO, and tether material are investigated.

  18. Spatial dynamics, thermalization, and gain clamping in a photon condensate

    NASA Astrophysics Data System (ADS)

    Keeling, Jonathan; Kirton, Peter

    2016-01-01

    We study theoretically the effects of pump-spot size and location on photon condensates. By exploring the inhomogeneous molecular excitation fraction, we make clear the relation between spatial equilibration, gain clamping, and thermalization in a photon condensate. This provides a simple understanding of several recent experimental results. We find that as thermalization breaks down, gain clamping is imperfect, leading to "transverse spatial hole burning" and multimode condensation. This opens the possibility of engineering the gain profile to control the condensate structure.

  19. Use of a photonic crystal for optical amplifier gain control

    SciTech Connect

    Lin, Shawn-Yu; Fleming, James G.; El-Kady, Ihab

    2006-07-18

    An optical amplifier having a uniform gain profile uses a photonic crystal to tune the density-of-states of a gain medium so as to modify the light emission rate between atomic states. The density-of-states of the gain medium is tuned by selecting the size, shape, dielectric constant, and spacing of a plurality of microcavity defects in the photonic crystal. The optical amplifier is particularly useful for the regeneration of DWDM signals in long optical fibers.

  20. Interleukin-18 Activates Skeletal Muscle AMPK and Reduces Weight Gain and Insulin Resistance in Mice

    PubMed Central

    Lindegaard, Birgitte; Matthews, Vance B.; Brandt, Claus; Hojman, Pernille; Allen, Tamara L.; Estevez, Emma; Watt, Matthew J.; Bruce, Clinton R.; Mortensen, Ole H.; Syberg, Susanne; Rudnicka, Caroline; Abildgaard, Julie; Pilegaard, Henriette; Hidalgo, Juan; Ditlevsen, Susanne; Alsted, Thomas J.; Madsen, Andreas N.; Pedersen, Bente K.; Febbraio, Mark A.

    2013-01-01

    Circulating interleukin (IL)-18 is elevated in obesity, but paradoxically causes hypophagia. We hypothesized that IL-18 may attenuate high-fat diet (HFD)-induced insulin resistance by activating AMP-activated protein kinase (AMPK). We studied mice with a global deletion of the α-isoform of the IL-18 receptor (IL-18R−/−) fed a standard chow or HFD. We next performed gain-of-function experiments in skeletal muscle, in vitro, ex vivo, and in vivo. We show that IL-18 is implicated in metabolic homeostasis, inflammation, and insulin resistance via mechanisms involving the activation of AMPK in skeletal muscle. IL-18R−/− mice display increased weight gain, ectopic lipid deposition, inflammation, and reduced AMPK signaling in skeletal muscle. Treating myotubes or skeletal muscle strips with IL-18 activated AMPK and increased fat oxidation. Moreover, in vivo electroporation of IL-18 into skeletal muscle activated AMPK and concomitantly inhibited HFD-induced weight gain. In summary, IL-18 enhances AMPK signaling and lipid oxidation in skeletal muscle implicating IL-18 in metabolic homeostasis. PMID:23670974

  1. Astronomers Gain Clues About Fundamental Physics

    NASA Astrophysics Data System (ADS)

    2005-12-01

    An international team of astronomers has looked at something very big -- a distant galaxy -- to study the behavior of things very small -- atoms and molecules -- to gain vital clues about the fundamental nature of our entire Universe. The team used the National Science Foundation's Robert C. Byrd Green Bank Telescope (GBT) to test whether the laws of nature have changed over vast spans of cosmic time. The Green Bank Telescope The Robert C. Byrd Green Bank Telescope CREDIT: NRAO/AUI/NSF (Click on image for GBT gallery) "The fundamental constants of physics are expected to remain fixed across space and time; that's why they're called constants! Now, however, new theoretical models for the basic structure of matter indicate that they may change. We're testing these predictions." said Nissim Kanekar, an astronomer at the National Radio Astronomy Observatory (NRAO), in Socorro, New Mexico. So far, the scientists' measurements show no change in the constants. "We've put the most stringent limits yet on some changes in these constants, but that's not the end of the story," said Christopher Carilli, another NRAO astronomer. "This is the exciting frontier where astronomy meets particle physics," Carilli explained. The research can help answer fundamental questions about whether the basic components of matter are tiny particles or tiny vibrating strings, how many dimensions the Universe has, and the nature of "dark energy." The astronomers were looking for changes in two quantities: the ratio of the masses of the electron and the proton, and a number physicists call the fine structure constant, a combination of the electron charge, the speed of light and the Planck constant. These values, considered fundamental physical constants, once were "taken as time independent, with values given once and forever" said German particle physicist Christof Wetterich. However, Wetterich explained, "the viewpoint of modern particle theory has changed in recent years," with ideas such as superstring theory and extra dimensions in spacetime calling for the "constants" to change over time, he said. The astronomers used the GBT to detect and study radio emissions at four specific frequencies between 1612 MHz and 1720 MHz coming from hydroxyl (OH) molecules in a galaxy more than 6 billion light-years from Earth, seen as it was at roughly half the Universe's current age. Each of the four frequencies represents a specific change in the energy level of the molecule. The exact frequency emitted or absorbed when the molecule undergoes a transition from one energy level to another depends on the values of the fundamental physical constants. However, each of the four frequencies studied in the OH molecule will react differently to a change in the constants. That difference is what the astronomers sought to detect using the GBT, which, Kanekar explained, is the ideal telescope for this work because of its technical capabilities and its location in the National Radio Quiet Zone, where radio interference is at a minimum. "We can place very tight limits on changes in the physical constants by studying the behavior of these OH molecules at a time when the Universe was only about half its current age, and comparing this result to how the molecules behave today in the laboratory," said Karl Menten of the Max-Planck Institute for Radioastronomy in Germany. Wetterich, a theorist, welcomes the new capability, saying the observational method "seems very promising to obtain perhaps the most accurate values for such possible time changes of the constants." He pointed out that, while some theoretical models call for the constants to change only in the early moments after the Big Bang, models of the recently-discovered, mysterious "dark energy" that seems to be accelerating the Universe's expansion call for changes "even in the last couple of billion years." "Only observations can tell," he said. This research ties together the theoretical and observational work of Wetterich and Carilli, this year's winners of the prestigious Max Planck Research Award of the Alexander von Humboldt Foundation and the Max Planck Society in Germany. Menten and Carilli have collaborated on research in this area for years, and Kanekar has pioneered the OH molecular technique. Kanekar, Carilli and Menten worked with Glen Langston of NRAO, Graca Rocha of the Cavendish Laboratory in the UK, Francoise Combes of the Paris Observatory, Ravi Subrahmanyan of the Australia Telescope National Facility (ATNF), John Stocke of the University of Colorado, Frank Briggs of the ATNF and the Australian National University, and Tommy Wiklind of the Space Telescope Science Institute in Sweden. The scientists reported their findings in the December 31 edition of the scientific journal Physical Review Letters.

  2. Population inversion and gain in expanding carbon fibre plasmas

    SciTech Connect

    Pert, G.J.; Shorrock, L.D.; Tallents, G.J.; Corbett, R.; Lamb, M.J.; Lewis, C.L.S.; Mahoney, E.; Eason, R.B.; Hooker, C.; Key, M.H.

    1984-09-01

    Carbon fibres of a few microns diameter, heated by a Nd:glass laser pulse offer a suitable medium for the generation of gain in the XUV spectral region. Population inversion occurs as recombination is induced by adiabatic cooling in the expansion of the hot fibre. Experimental results and their interpretation using computer modelling have given a good understanding of the underlying physics, and show two regimes of operation: one of high gain places stringent limitations of the uniformity of illumination, the other of lower gain on the length of cylindrical focus. The design constraints on high gain and acceptable experimental tolerance are discussed.

  3. Instantaneous diversity gain in 10-30 GHz satellite systems

    NASA Technical Reports Server (NTRS)

    Towner, G. C., III; Bostian, C. W.; Stutzman, W. L.; Pratt, T.

    1984-01-01

    As usually defined, diversity gain is a statistical measure which conveys little or no information about the instantaneous behavior of site-diversity reception in a satellite communications system. A new quantity called instantaneous diversity gain is introduced and some measurements of it from an 11.6 GHz low-angle two-site downlink are presented. It is shown how instantaneous diversity gain is related to system reliability and some results are presented which indicate that designs based on statistical diversity gain will achieve their intended reliability levels.

  4. Lunar transportation scenarios utilising the Space Elevator.

    PubMed

    Engel, Kilian A

    2005-01-01

    The Space Elevator (SE) concept has begun to receive an increasing amount of attention within the space community over the past couple of years and is no longer widely dismissed as pure science fiction. In light of the renewed interest in a, possibly sustained, human presence on the Moon and the fact that transportation and logistics form the bottleneck of many conceivable lunar missions, it is interesting to investigate what role the SE could eventually play in implementing an efficient Earth to Moon transportation system. The elevator allows vehicles to ascend from Earth and be injected into a trans-lunar trajectory without the use of chemical thrusters, thus eliminating gravity loss, aerodynamic loss and the need of high thrust multistage launch systems. Such a system therefore promises substantial savings of propellant and structural mass and could greatly increase the efficiency of Earth to Moon transportation. This paper analyzes different elevator-based trans-lunar transportation scenarios and characterizes them in terms of a number of benchmark figures. The transportation scenarios include direct elevator-launched trans-lunar trajectories, elevator launched trajectories via L1 and L2, as well as launch from an Earth-based elevator and subsequent rendezvous with lunar elevators placed either on the near or on the far side of the Moon. The benchmark figures by which the different transfer options are characterized and evaluated include release radius (RR), required delta v, transfer times as well as other factors such as accessibility of different lunar latitudes, frequency of launch opportunities and mission complexity. The performances of the different lunar transfer options are compared with each other as well as with the performance of conventional mission concepts, represented by Apollo. PMID:16010760

  5. Elevational Distribution and Extinction Risk in Birds

    PubMed Central

    White, Rachel L.; Bennett, Peter M.

    2015-01-01

    Mountainous regions are hotspots of terrestrial biodiversity. Unlike islands, which have been the focus of extensive research on extinction dynamics, fewer studies have examined mountain ranges even though they face increasing threats from human pressures – notably habitat conversion and climate change. Limits to the taxonomic and geographical extent and resolution of previously available information have precluded an explicit assessment of the relative role of elevational distribution in determining extinction risk. We use a new global species-level avian database to quantify the influence of elevational distribution (range, maximum and midpoint) on extinction risk in birds at the global scale. We also tested this relationship within biogeographic realms, higher taxonomic levels, and across phylogenetic contrasts. Potential confounding variables (i.e. phylogenetic, distributional, morphological, life history and niche breadth) were also tested and controlled for. We show that the three measures of elevational distribution are strong negative predictors of avian extinction risk, with elevational range comparable and complementary to that of geographical range size. Extinction risk was also found to be positively associated with body weight, development and adult survival, but negatively associated with reproduction and niche breadth. The robust and consistent findings from this study demonstrate the importance of elevational distribution as a key driver of variation in extinction dynamics in birds. Our results also highlight elevational distribution as a missing criterion in current schemes for quantifying extinction risk and setting species conservation priorities in birds. Further research is recommended to test for generality across non-avian taxa, which will require an advance in our knowledge of species’ current elevational ranges and increased efforts to digitise and centralise such data. PMID:25849620

  6. Lunar transportation scenarios utilising the Space Elevator

    NASA Astrophysics Data System (ADS)

    Engel, Kilian A.

    2005-07-01

    The Space Elevator (SE) concept has begun to receive an increasing amount of attention within the space community over the past couple of years and is no longer widely dismissed as pure science fiction. In light of the renewed interest in a, possibly sustained, human presence on the Moon and the fact that transportation and logistics form the bottleneck of many conceivable lunar missions, it is interesting to investigate what role the SE could eventually play in implementing an efficient Earth to Moon transportation system. The elevator allows vehicles to ascend from Earth and be injected into a trans-lunar trajectory without the use of chemical thrusters, thus eliminating gravity loss, aerodynamic loss and the need of high thrust multistage launch systems. Such a system therefore promises substantial savings of propellant and structural mass and could greatly increase the efficiency of Earth to Moon transportation. This paper analyzes different elevator-based trans-lunar transportation scenarios and characterizes them in terms of a number of benchmark figures. The transportation scenarios include direct elevator-launched trans-lunar trajectories, elevator-launched trajectories via L1 and L2, as well as launch from an Earth-based elevator and subsequent rendezvous with lunar elevators placed either on the near or on the far side of the Moon. The benchmark figures by which the different transfer options are characterized and evaluated include release radius (RR), required ?v, transfer times as well as other factors such as accessibility of different lunar latitudes, frequency of launch opportunities and mission complexity. The performances of the different lunar transfer options are compared with each other as well as with the performance of conventional mission concepts, represented by Apollo.

  7. Quantification of glacier elevation changes using ICESat and SRTM elevation data in the Upper Indus Basin

    NASA Astrophysics Data System (ADS)

    Naz, B. S.; Bowling, L. C.; Crawford, M. M.

    2010-12-01

    Recent studies carried out in the Karakoram Himalayas suggest an expansion of glaciers. Many studies conducted in the Himalayan region have focused on monitoring changes in the aerial extent of individual glaciers from remotely sensed data or through field surveys. Limited work, however, has been done in this region to estimate glacier volume changes using measurements of elevation change over time, particularly at a large scale. Here we used Ice, Cloud and Land Elevation Satellite (ICESat) and the Shuttle Radar Topography Mission (SRTM) data to estimate glacier elevation changes within the Upper Indus River Basin (UIB). The elevation changes were estimated within snow-covered and clean-ice zones which were delineated using historic Land Remote-Sensing Satellite (Landsat) images. ICESat/GLA06 elevations data from spring campaigns, release 28 were used to estimate ice elevation changes for the period of 2004-2008 relative to 2000. The accuracy of elevation change was assessed by analyzing non-glacier elevation difference points within different categories of a Terrain Ruggedness Index (TRI). This comparison showed that elevations precision decreased with increasing TRI, so using TRI to categorize glacier areas helps to identify data points with higher accuracy. Our analysis of elevation changes estimated from the ICESat altimeter identified two clear patterns in elevation changes. Firstly, glaciers in the northern half of the Upper Indus valley have thickened in the last decade, while those in the southern sub-watersheds are thinning. Secondly, glacier thickening occurred on the higher elevation snow-covered ice zone, while more thinning rates were observed within the clean ice zone for all sub-watersheds of the UIB, except in the Hunza river basin. Such results showed the potential of ICESat data for assessing relief changes on mountain glaciers and could be used in the estimation of glacier mass balance at higher temporal resolutions.

  8. Space Elevator Concept Considered a Reality

    NASA Technical Reports Server (NTRS)

    2000-01-01

    The `once upon a time' science fiction concept of a space elevator has been envisioned and studied as a real mass transportation system in the latter part of the 21st century. David Smitherman of NASA's Marshall Space Flight Center's Advanced Projects Office has compiled plans for such an elevator. The space elevator concept is a structure extending from the surface of the Earth to geostationary Earth orbit (GEO) at 35,786 km in altitude. The tower would be approximately 50 km tall with a cable tethered to the top. Its center mass would be at GEO such that the entire structure orbits the Earth in sync with the Earth's rotation maintaining a stationary position over its base attachment at the equator. Electromagnetic vehicles traveling along the cable could serve as a mass transportation system for transporting people, payloads, and power between space and Earth. This illustration by artist Pat Rawling shows the concept of a space elevator as viewed from the geostationary transfer station looking down the length of the elevator towards the Earth.

  9. Feasibility Study of a Stratospheric Elevator

    NASA Astrophysics Data System (ADS)

    Yamagiwa, Yoshiki; Nakata, Masafumi; Miwa, Toru; Matsui, Makoto

    As a first step in the development of a space elevator, we focused on the stratospheric platform that would be used as a relay station of communication and high-resolution earth observation base at 20~30 km altitude. We propose a new system for connecting the platform to the ground by a tether that would allow the payload to be transported by a climber moving along the tether. We call this system a stratospheric elevator. The stratospheric elevator offers not only the chance to verify the space elevator technology but also the chance to extend the life of the platform by making its maintenance easy. The result of our initial study of the system showed that we can build a stratospheric elevator using currently available materials and technology. The total tether system, including a 200 kg payload and a 200 kg climber, would weigh about 2 tons with considering the effect of the high-speed airstream when we built the system at 20 km altitude, and a platform of about 80 m diameter could sustain the total system.

  10. The Causes of and Gains from Intertemporal Trade

    ERIC Educational Resources Information Center

    Craighead, William D.; Miller, Norman C.

    2010-01-01

    The authors show how the causes of and the gains from current account imbalances can be integrated into undergraduate economics courses using the same pedagogical tools that are used to explain comparative advantage and the gains from trade. A nonzero current account provides a mechanism for intertemporal trade, and a country has a comparative…

  11. Psychological Adjustment of Adolescents Attempting to Lose or Gain Weight.

    ERIC Educational Resources Information Center

    Rosen, James C.; And Others

    1987-01-01

    Compared the psychological adjustment of high school boys and girls trying to reduce or gain weight. Reducers of both sexes and male gainers exhibited lower physical self-esteem. Girls trying to change weight in either direction showed depression and lower global self-esteem. Girls' decisions to gain or lose weight were influenced by psychological

  12. A variable-gain output feedback control design methodology

    NASA Technical Reports Server (NTRS)

    Halyo, Nesim; Moerder, Daniel D.; Broussard, John R.; Taylor, Deborah B.

    1989-01-01

    A digital control system design technique is developed in which the control system gain matrix varies with the plant operating point parameters. The design technique is obtained by formulating the problem as an optimal stochastic output feedback control law with variable gains. This approach provides a control theory framework within which the operating range of a control law can be significantly extended. Furthermore, the approach avoids the major shortcomings of the conventional gain-scheduling techniques. The optimal variable gain output feedback control problem is solved by embedding the Multi-Configuration Control (MCC) problem, previously solved at ICS. An algorithm to compute the optimal variable gain output feedback control gain matrices is developed. The algorithm is a modified version of the MCC algorithm improved so as to handle the large dimensionality which arises particularly in variable-gain control problems. The design methodology developed is applied to a reconfigurable aircraft control problem. A variable-gain output feedback control problem was formulated to design a flight control law for an AFTI F-16 aircraft which can automatically reconfigure its control strategy to accommodate failures in the horizontal tail control surface. Simulations of the closed-loop reconfigurable system show that the approach produces a control design which can accommodate such failures with relative ease. The technique can be applied to many other problems including sensor failure accommodation, mode switching control laws and super agility.

  13. Behavioral Treatment Approaches to Prevent Weight Gain Following Smoking Cessation.

    ERIC Educational Resources Information Center

    Grinstead, Olga A.

    Personality and physiological, cognitive, and environmental factors have all been suggested as critical variables in smoking cessation and relapse. Weight gain and the fear of weight gain after smoking cessation may also prevent many smokers from quitting. A sample of 45 adult smokers participated in a study in which three levels of preventive

  14. Quantifying the mechanisms of domain gain in animal proteins

    PubMed Central

    2010-01-01

    Background Protein domains are protein regions that are shared among different proteins and are frequently functionally and structurally independent from the rest of the protein. Novel domain combinations have a major role in evolutionary innovation. However, the relative contributions of the different molecular mechanisms that underlie domain gains in animals are still unknown. By using animal gene phylogenies we were able to identify a set of high confidence domain gain events and by looking at their coding DNA investigate the causative mechanisms. Results Here we show that the major mechanism for gains of new domains in metazoan proteins is likely to be gene fusion through joining of exons from adjacent genes, possibly mediated by non-allelic homologous recombination. Retroposition and insertion of exons into ancestral introns through intronic recombination are, in contrast to previous expectations, only minor contributors to domain gains and have accounted for less than 1% and 10% of high confidence domain gain events, respectively. Additionally, exonization of previously non-coding regions appears to be an important mechanism for addition of disordered segments to proteins. We observe that gene duplication has preceded domain gain in at least 80% of the gain events. Conclusions The interplay of gene duplication and domain gain demonstrates an important mechanism for fast neofunctionalization of genes. PMID:20633280

  15. 26 CFR 1.737-1 - Recognition of precontribution gain.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 8 2011-04-01 2011-04-01 false Recognition of precontribution gain. 1.737-1 Section 1.737-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Distributions by A Partnership 1.737-1 Recognition of precontribution gain. (a) Determination of...

  16. Validity of Sudden Gains in Acute Phase Treatment of Depression

    ERIC Educational Resources Information Center

    Vittengl, Jeffrey R.; Clark, Lee Anna; Jarrett, Robin B.

    2005-01-01

    The authors examined the validity of sudden gains identified with T. Z. Tang and R. J. DeRubeis's (1999) method in 2 clinical data sets that involved treatment of major depressive disorder (N=227). Sudden gains replicated among self- and clinician reports of depressive symptoms and predicted better psychosocial functioning at the acute phase…

  17. The Causes of and Gains from Intertemporal Trade

    ERIC Educational Resources Information Center

    Craighead, William D.; Miller, Norman C.

    2010-01-01

    The authors show how the causes of and the gains from current account imbalances can be integrated into undergraduate economics courses using the same pedagogical tools that are used to explain comparative advantage and the gains from trade. A nonzero current account provides a mechanism for intertemporal trade, and a country has a comparative

  18. 26 CFR 7.105-2 - Substantial gainful activity.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 14 2012-04-01 2012-04-01 false Substantial gainful activity. 7.105-2 Section 7.105-2 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) TEMPORARY INCOME TAX REGULATIONS UNDER THE TAX REFORM ACT OF 1976 7.105-2 Substantial gainful activity. (a) Purpose. This...

  19. Sustaining Student Gains from Online On-Demand Professional Development

    ERIC Educational Resources Information Center

    Shaha, Steven H.; Glassett, Kelly; Copas, Aimee

    2015-01-01

    A multi-State, quasi-experimental study was conducted as a longitudinal, two-year follow-up of participation in an online, on-demand professional development (PD) program. The purpose was to ascertain whether student gains were sustained in a second year of PD participation. Data verified gains in Year 1 versus Pre-PD baseline, with continued…

  20. 24 CFR 3280.507 - Comfort heat gain.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 5 2014-04-01 2014-04-01 false Comfort heat gain. 3280.507 Section... DEVELOPMENT MANUFACTURED HOME CONSTRUCTION AND SAFETY STANDARDS Thermal Protection § 3280.507 Comfort heat... part. (a) Transmission heat gains. Homes complying with this section shall meet the minimum heat...

  1. 24 CFR 3280.507 - Comfort heat gain.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 5 2012-04-01 2012-04-01 false Comfort heat gain. 3280.507 Section... DEVELOPMENT MANUFACTURED HOME CONSTRUCTION AND SAFETY STANDARDS Thermal Protection § 3280.507 Comfort heat... part. (a) Transmission heat gains. Homes complying with this section shall meet the minimum heat...

  2. 24 CFR 3280.507 - Comfort heat gain.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 5 2013-04-01 2013-04-01 false Comfort heat gain. 3280.507 Section... DEVELOPMENT MANUFACTURED HOME CONSTRUCTION AND SAFETY STANDARDS Thermal Protection § 3280.507 Comfort heat... part. (a) Transmission heat gains. Homes complying with this section shall meet the minimum heat...

  3. 24 CFR 3280.507 - Comfort heat gain.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 5 2011-04-01 2011-04-01 false Comfort heat gain. 3280.507 Section... DEVELOPMENT MANUFACTURED HOME CONSTRUCTION AND SAFETY STANDARDS Thermal Protection § 3280.507 Comfort heat... part. (a) Transmission heat gains. Homes complying with this section shall meet the minimum heat...

  4. 24 CFR 3280.507 - Comfort heat gain.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Comfort heat gain. 3280.507 Section... DEVELOPMENT MANUFACTURED HOME CONSTRUCTION AND SAFETY STANDARDS Thermal Protection § 3280.507 Comfort heat... part. (a) Transmission heat gains. Homes complying with this section shall meet the minimum heat...

  5. 5. VIEW OF SECOND ELEVATOR WITH WOODFRAME HEADHOUSE AND ASPHALTIC ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. VIEW OF SECOND ELEVATOR WITH WOOD-FRAME HEADHOUSE AND ASPHALTIC SIDING, LOOKING WEST. - Lockport DuPage Farmer's Elevator Company Grain Elevator, South of Romeoville Road, Lockport, Will County, IL

  6. 2. GLF, north elevation. Visible from left to right ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. GLF, north elevation. Visible from left to right - elevator C, and B, feed mill in foreground, and former molasses storage tanks. - Cooperative Grange League Federation Elevator, 385 Ganson Street, Buffalo, Erie County, NY

  7. 43. Elevation looking west, the Merle M. MC Curdy in ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    43. Elevation looking west, the Merle M. MC Curdy in the foreground, the great northen elevator in the background. Jet Lowe, photographer, 1985. - Great Northern Elevator, 250 Ganson Street, Buffalo, Erie County, NY

  8. 29. Elevator no. 3: top floor, conveyor belt rollers for ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    29. Elevator no. 3: top floor, conveyor belt rollers for belt to gangway (in background) connecting with elevator no. 2, facing northwest - Washburn Crosby Company Elevators No. 2 & 3, 900 & 1000 Second Avenue, South, Minneapolis, Hennepin County, MN

  9. Complex motion induced by elevator choice in peak traffic

    NASA Astrophysics Data System (ADS)

    Nagatani, Takashi

    2015-10-01

    We study the dynamic motion of two elevators by an elevator-choice strategy of passengers. An elevator is correlated with another elevator by the elevator choice. The dynamics of the elevator traffic system is described by a pair of deterministic nonlinear maps. The motion of two elevators is determined by the three parameters: the passenger's preference, the fraction of fast passengers, and the inflow rate. The dynamics of two elevators depends highly on the elevator-choice strategy. The motion of two elevators displays a complex behavior by a neck-and-neck race between two elevators. We explore the dependence of elevator motion on the passenger's preference, the fraction of fast passengers, and the inflow rate.

  10. Ice elevation change from Swath Processing of CryoSat SARIn Mode Data

    NASA Astrophysics Data System (ADS)

    Foresta, Luca; Gourmelen, Noel; Shepherd, Andrew; Muir, Alan; Nienow, Pete

    2015-04-01

    Reference and repeat-observations of Glacier and Ice Sheet Margin (GISM) topography are critical to identify changes in ice elevation, provide estimates of mass gain or loss and thus quantify the contribution of the cryosphere to sea level rise (e.g. McMillan et al., 2014). The Synthetic Interferometric Radar Altimeter (SIRAL) onboard the ESA radar altimetry CryoSat (CS) mission has collected ice elevation measurements since 2010. The corresponding SARIn mode of operation, activated over GISM areas, provides high spatial resolution in the along-track direction while resolving the angular origin of echoes (i.e. across-track). The current ESA SARIn processor calculates the elevation of the Point Of Closest Approach (POCA) within each waveform and maps of elevation change in Antarctica and Greenland have been produced using the regular CS height product (McMillan et al., 2014; Helm et al., 2014). Data from the CS-SARIn mode has also been used to produce measurements of ice elevation beyond the POCA, also known as swath elevation (Hawley et al. 2009; Gray et al., 2013; ESA-STSE CryoTop project). Here we use the swath processing approach to generate maps of ice elevation change from selected regions around the margins of the Greenland and Antarctic Ice Sheets. We discuss the impact of the swath processing on the spatial resolution and precision of the resulting ice elevation field and compare our results to current dh/dt estimates. References: ESA STSE CryoTop project - http://www.stse-cryotop.org/ Gray L., Burgess D., Copland L., Cullen R., Galin N., Hawley R. and Helm V. Interferometric swath processing of Cryosat data for glacial ice topography. The Cryosphere, 7(6):1857-1867, December 2013. Hawley R.L., Shepherd A., Cullen R., Helm V. and WIngham D.J. Ice-sheet elevations from across-track processing of airborne interferometric radar altimetry. Geophysical Research Letters, 36(22):L22501, November 2009. Helm V., Humbert A. and Miller H. Elevation and elevation change of Greenland and Antarctica derived from CryoSat-2. The Cryosphere, 8(4):1539-1559, August 2014. McMillan M., Shepherd A., Sundal A., Briggs K., Muir A., Ridout A., Hogg A. and Wingham D. Increased ice losses from Antarctica detected by CryoSat-2. Geophysical Research Letters, pages 3899-3905, 2014.

  11. Characterization of ultrasound elevation beamwidth artifacts for prostate brachytherapy needle insertion

    SciTech Connect

    Peikari, Mohammad; Chen, Thomas Kuriran; Lasso, Anras; Heffter, Tamas; Fichtinger, Gabor; Burdette, Everette C.

    2012-01-15

    Purpose: Ultrasound elevation beamwidth leads to image artifacts and uncertainties in localizing objects (such as a surgical needle) in ultrasound images. The authors examined the clinical significance of errors caused by elevation beamwidth artifacts and imaging parameters in needle insertion procedures. Methods: Beveled prostate brachytherapy needles were inserted through all holes of a grid template under real-time transrectal ultrasound (TRUS) guidance. The needle tip position as indicated by the TRUS image was compared to their observed physical location. A new device was developed to measure the ultrasound elevation beamwidth. Results: Imaging parameters of the TRUS scanner have direct impact on the localization error ranging from 0.5 up to 4 mm. The smallest localization error was observed laterally close to the center of the grid template and axially within the beam's focal zone. Largest localization error occurs laterally around both sides of the grid template and axially within the beam's far field. The authors also found that the localization errors vary with both lateral and elevation offsets. Conclusions: The authors found properly adjusting the TRUS imaging settings to lower the ultrasound gain and power effectively minimized the appearance of elevation beamwidth artifacts and in turn reduced the localization errors of the needle tip.

  12. Adaptive gain and filtering circuit for a sound reproduction system

    NASA Technical Reports Server (NTRS)

    Engebretson, A. Maynard (Inventor); O'Connell, Michael P. (Inventor)

    1998-01-01

    Adaptive compressive gain and level dependent spectral shaping circuitry for a hearing aid include a microphone to produce an input signal and a plurality of channels connected to a common circuit output. Each channel has a preset frequency response. Each channel includes a filter with a preset frequency response to receive the input signal and to produce a filtered signal, a channel amplifier to amplify the filtered signal to produce a channel output signal, a threshold register to establish a channel threshold level, and a gain circuit. The gain circuit increases the gain of the channel amplifier when the channel output signal falls below the channel threshold level and decreases the gain of the channel amplifier when the channel output signal rises above the channel threshold level. A transducer produces sound in response to the signal passed by the common circuit output.

  13. Low Gestational Weight Gain in Obese Women and Pregnancy Outcomes

    PubMed Central

    Moehlecke, Milene; Costenaro, Fabola; Reichelt, Angela AJ; Oppermann, Maria Lcia R.; Leito, Cristiane B.

    2015-01-01

    Obesity during pregnancy and excessive weight gain during this period are associated with several maternalfetal and neonatal complications. Moreover, a significant percentage of women have weight retention in the postpartum period, especially those with excessive weight gain during pregnancy. The recommendations of the 2009 Institute of Medicine were based on observational studies that have consistently shown that women with weight gain within the recommended range had better outcomes during pregnancy. In patients with obesity, however, there is no recommendation for weight gain, according to the class of obesity. This review, therefore, aims to evaluate the evidence on key maternal and fetal complications related to low weight gain during pregnancy in obese and overweight patients. PMID:26929877

  14. Clinically Significant Weight Gain One Year After Occupational Back Injury

    PubMed Central

    Keeney, Benjamin J.; Fulton-Kehoe, Deborah; Wickizer, Thomas M.; Turner, Judith A.; Chan, Kwun Chuen Gary; Franklin, Gary M.

    2014-01-01

    Objective To examine the incidence of clinically significant weight gain one year after occupational back injury, and risk factors for that gain. Methods A cohort of Washington State workers with wage-replacement benefits for back injuries completed baseline and 1-year follow-up telephone interviews. We obtained additional measures from claims and medical records. Results Among 1,263 workers, 174 (13.8%) reported clinically significant weight gain (?7%) 1 year after occupational back injury. Women and workers who had >180 days on wage replacement at 1 year were twice as likely (adjusted OR=2.17, 95% CI=1.543.07; adjusted OR=2.40, 95% CI=1.633.53, respectively; both P<0.001) to have clinically significant weight gain. Conclusions Women and workers on wage replacement >180 days may be susceptible to clinically significant weight gain following occupational back injury. PMID:23247606

  15. Impact of GEM foil hole geometry on GEM detector gain

    NASA Astrophysics Data System (ADS)

    Karadzhinova, A.; Nolvi, A.; Veenhof, R.; Tuominen, E.; Hggstrm, E.; Kassamakov, I.

    2015-12-01

    Detailed 3D imaging of Gas Electron Multiplier (GEM) foil hole geometry was realized. Scanning White Light Interferometry was used to examine six topological parameters of GEM foil holes from both sides of the foil. To study the effect of the hole geometry on detector gain, the ANSYS and Garfield ++ software were employed to simulate the GEM detector gain on the basis of SWLI data. In particular, the effective gain in a GEM foil with equally shaped holes was studied. The real GEM foil holes exhibited a 4% lower effective gain and 6% more electrons produced near the exit electrode of the GEM foil than the design anticipated. Our results indicate that the GEM foil hole geometry affects the gain performance of GEM detectors.

  16. Low Gestational Weight Gain in Obese Women and Pregnancy Outcomes.

    PubMed

    Moehlecke, Milene; Costenaro, Fabíola; Reichelt, Angela Aj; Oppermann, Maria Lúcia R; Leitão, Cristiane B

    2016-03-01

    Obesity during pregnancy and excessive weight gain during this period are associated with several maternal-fetal and neonatal complications. Moreover, a significant percentage of women have weight retention in the postpartum period, especially those with excessive weight gain during pregnancy. The recommendations of the 2009 Institute of Medicine were based on observational studies that have consistently shown that women with weight gain within the recommended range had better outcomes during pregnancy. In patients with obesity, however, there is no recommendation for weight gain, according to the class of obesity. This review, therefore, aims to evaluate the evidence on key maternal and fetal complications related to low weight gain during pregnancy in obese and overweight patients. PMID:26929877

  17. Weight gain associated with neuroleptic medication: a review.

    PubMed

    Stanton, J M

    1995-01-01

    In this article we review the empirical literature on weight gain associated with neuroleptic drug use. Weight gain, which appears to be associated with an increase in appetite, is variable but likely to be larger initially and then plateau. Clozapine and low-potency phenothiazines are associated with the largest gains and molindone with weight loss, but the mechanism is not known. Amantadine and fenfluramine may reverse weight gain to some degree. Dietary fat seems to play an important role in obesity, and research is needed to increase the data base and elucidate possible mechanisms. Studies are also needed to evaluate preventive strategies and to determine which drugs are least likely to produce weight gain as well as which drugs could be added to a neuroleptic regimen to control weight. PMID:7481576

  18. How Pregnant African-American Women View Pregnancy Weight Gain

    PubMed Central

    Groth, Susan W.; Morrison-Beedy, Dianne; Meng, Ying

    2012-01-01

    Objective To gain insight into how low-income, pregnant African-American women viewed their weight gain while pregnant and how they managed their weight during pregnancy. Design Descriptive study using three focus groups. Setting Women were recruited from urban prenatal care sites and the Special Supplemental Nutrition Program for Women, Infants and Children (WIC) services in a medium-sized urban Northeastern city. Participants Twenty-six adult, low-income, pregnant African-American women, aged 18–39; the majority were within the first 20 weeks of pregnancy. Methods Three focus groups were conducted utilizing open-ended questions related to pregnancy weight gain. Content analysis was used to analyze the verbatim transcripts. Analysis focused on meaning, intention and context. Groups were compared and contrasted at the within and between group levels to identify themes. Results Four themes were identified that provided insight into how women viewed their pregnancy weight gain and managed weight gain during pregnancy: (a) pregnancy weight gain: no matter how much means a healthy baby; (b) weight retention: it happens; (c) there is a limit: weight gain impact on appearance; and (d) watching and waiting: plans for controlling weight. Conclusion Low-income African-American women, though cognizant of the likelihood of retention of weight following pregnancy, are not focused on limiting their gestational weight gain. The cultural acceptance of a larger body size along with the belief that gaining more weight is indicative of a healthy infant present challenges for interventions to limit excessive gestational weight gain. PMID:22789036

  19. Relationship Between Optimal Gain and Coherence Zone in Flight Simulation

    NASA Technical Reports Server (NTRS)

    Gracio, Bruno Jorge Correia; Pais, Ana Rita Valente; vanPaassen, M. M.; Mulder, Max; Kely, Lon C.; Houck, Jacob A.

    2011-01-01

    In motion simulation the inertial information generated by the motion platform is most of the times different from the visual information in the simulator displays. This occurs due to the physical limits of the motion platform. However, for small motions that are within the physical limits of the motion platform, one-to-one motion, i.e. visual information equal to inertial information, is possible. It has been shown in previous studies that one-to-one motion is often judged as too strong, causing researchers to lower the inertial amplitude. When trying to measure the optimal inertial gain for a visual amplitude, we found a zone of optimal gains instead of a single value. Such result seems related with the coherence zones that have been measured in flight simulation studies. However, the optimal gain results were never directly related with the coherence zones. In this study we investigated whether the optimal gain measurements are the same as the coherence zone measurements. We also try to infer if the results obtained from the two measurements can be used to differentiate between simulators with different configurations. An experiment was conducted at the NASA Langley Research Center which used both the Cockpit Motion Facility and the Visual Motion Simulator. The results show that the inertial gains obtained with the optimal gain are different than the ones obtained with the coherence zone measurements. The optimal gain is within the coherence zone.The point of mean optimal gain was lower and further away from the one-to-one line than the point of mean coherence. The zone width obtained for the coherence zone measurements was dependent on the visual amplitude and frequency. For the optimal gain, the zone width remained constant when the visual amplitude and frequency were varied. We found no effect of the simulator configuration in both the coherence zone and optimal gain measurements.

  20. Elevated temperature deformation of TD-nickel.

    NASA Technical Reports Server (NTRS)

    Petrovic, J. J.; Ebert, L. J.

    1973-01-01

    Sensitivity of the elevated temperature (above 0.5 Tm) deformation of TD-nickel to grain size and shape was examined in both tension and creep. Elevated temperature strength increased with increasing grain diameter and increasing L/D ratio. Temperature sensitivity of the yield stress, as well as high (compared to self diffusion) apparent tensile activation enthalpies were the result of the internal stress not being proportional to the shear modulus. Creep activation enthalpies increased with increasing L/D ratio and, to a lesser extent, increasing grain diameter, reaching high values which may be apparent values. The thoria particle dispersion may have been altered by elevated temperature tensile and creep deformation.

  1. Advanced composite elevator for Boeing 727 aircraft

    NASA Technical Reports Server (NTRS)

    1979-01-01

    Detail design activities are reported for a program to develop an advanced composites elevator for the Boeing 727 commercial transport. Design activities include discussion of the full scale ground test and flight test activities, the ancillary test programs, sustaining efforts, weight status, and the production status. Prior to flight testing of the advanced composites elevator, ground, flight flutter, and stability and control test plans were reviewed and approved by the FAA. Both the ground test and the flight test were conducted according to the approved plan, and were witnessed by the FAA. Three and one half shipsets have now been fabricated without any significant difficulty being encountered. Two elevator system shipsets were weighed, and results validated the 26% predicted weight reduction. The program is on schedule.

  2. Vertical vibration analysis for elevator compensating sheave

    NASA Astrophysics Data System (ADS)

    Watanabe, Seiji; Okawa, Takeya; Nakazawa, Daisuke; Fukui, Daiki

    2013-07-01

    Most elevators applied to tall buildings include compensating ropes to satisfy the balanced rope tension between the car and the counter weight. The compensating ropes receive tension by the compensating sheave, which is installed at the bottom space of the elevator shaft. The compensating sheave is only suspended by the compensating ropes, therefore, the sheave can move vertically while the car is traveling. This paper shows the elevator dynamic model to evaluate the vertical motion of the compensating sheave. Especially, behavior in emergency cases, such as brake activation and buffer strike, was investigated to evaluate the maximum upward motion of the sheave. The simulation results were validated by experiments and the most influenced factor for the sheave vertical motion was clarified.

  3. The physics of the space elevator

    NASA Astrophysics Data System (ADS)

    Aravind, P. K.

    2007-02-01

    A space elevator is a tall tower rising from a point on the Earth's equator to a height well above a geostationary orbit, where it terminates in a counterweight. Although the concept is more than a century old, it was only with the discovery of carbon nanotubes that it began to receive serious scientific attention. NASA commissioned a study of the space elevator in the late 1990s that examined the feasibility of such a structure and explored many of its applications. I explain the basic mechanical principles underlying the construction of a space elevator and discuss several of its applications: the transport of payload into space and the launching of spacecraft on voyages to other planets.

  4. A new bed elevation dataset for Greenland

    NASA Astrophysics Data System (ADS)

    Bamber, J. L.; Griggs, J. A.; Hurkmans, R. T. W. L.; Dowdeswell, J. A.; Gogineni, S. P.; Howat, I.; Mouginot, J.; Paden, J.; Palmer, S.; Rignot, E.; Steinhage, D.

    2013-03-01

    We present a new bed elevation dataset for Greenland derived from a combination of multiple airborne ice thickness surveys undertaken between the 1970s and 2012. Around 420 000 line kilometres of airborne data were used, with roughly 70% of this having been collected since the year 2000, when the last comprehensive compilation was undertaken. The airborne data were combined with satellite-derived elevations for non-glaciated terrain to produce a consistent bed digital elevation model (DEM) over the entire island including across the glaciated-ice free boundary. The DEM was extended to the continental margin with the aid of bathymetric data, primarily from a compilation for the Arctic. Ice thickness was determined where an ice shelf exists from a combination of surface elevation and radar soundings. The across-track spacing between flight lines warranted interpolation at 1 km postings for significant sectors of the ice sheet. Grids of ice surface elevation, error estimates for the DEM, ice thickness and data sampling density were also produced alongside a mask of land/ocean/grounded ice/floating ice. Errors in bed elevation range from a minimum of 10 m to about 300 m, as a function of distance from an observation and local topographic variability. A comparison with the compilation published in 2001 highlights the improvement in resolution afforded by the new datasets, particularly along the ice sheet margin, where ice velocity is highest and changes in ice dynamics most marked. We estimate that the volume of ice included in our land-ice mask would raise mean sea level by 7.36 m, excluding any solid earth effects that would take place during ice sheet decay.

  5. 23. VIEW SECOND FLOOR, ELEVATOR SHAFT SAFETY NET ACCESS, NORTHWEST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    23. VIEW SECOND FLOOR, ELEVATOR SHAFT SAFETY NET ACCESS, NORTHWEST ELEVATOR LOADING DOOR. - Bates Manufacturing Company, Storehouse, Northeast corner of Chestnut Street & Hines Alley, Lewiston, Androscoggin County, ME

  6. Elevated atmospheric carbon dioxide increases soil carbon

    SciTech Connect

    Norby, Richard J; Jastrow, Julie D; Miller, Michael R; Matamala, Roser; Boutton, Thomas W; Rice, Charles W; Owensby, Clenton E

    2005-01-01

    In a study funded by the U.S. Department of Energy's Office of Science, researchers from Argonne and Oak Ridge National Laboratories and Kansas State and Texas A&M Universities evaluated the collective results of earlier studies by using a statistical procedure called meta-analysis. They found that on average elevated CO2 increased soil carbon by 5.6 percent over a two to nine year period. They also measured comparable increases in soil carbon for Tennessee deciduous forest and Kansas grassland after five to eight years of experimental exposure to elevated CO2.

  7. Accurately control and flatten gain spectrum of L-band erbium doped fiber amplifier based on suitable gain-clamping

    NASA Astrophysics Data System (ADS)

    Yang, Jiuru; Meng, Xiangyu; Liu, Chunyu

    2016-04-01

    The increasing traffic with dynamic nature requires the applications of gain-clamped L-band erbium-doped fiber amplifier (EDFA). However, the weak or over clamping may lead the unexpected gain-compression and flatness-worsening. In this article, to enhance practicality, we modify the partly gain-clamping configuration and utilize a pair of C-band fiber Bragg gratings (FBGs) to non-uniformly compress the gain spectrum of L-band. Through a comprehensive test and comparison, the suitable gain-clamping region for the amplified signals is found, and the gain in L-band is accurately controlled and flattened under the matched central wavelength of FBGs. The experimental results show that, our designed L-band EDFA achieves a trade-off among the output gain, flatness and stability. The ±0.44 dB flatness and 20.2 dB average gain are together obtained in the range of 1570-1610 nm, with the ±0.1 dB stability of signals in over 30 dBm dynamic range.

  8. 26 CFR 1.1287-1 - Denial of capital gains treatment for gains on registration-required obligations not in...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 11 2011-04-01 2011-04-01 false Denial of capital gains treatment for gains on registration-required obligations not in registered form. 1.1287-1 Section 1.1287-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Special Rules for...

  9. 26 CFR 1.1287-1 - Denial of capital gains treatment for gains on registration-required obligations not in...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 11 2012-04-01 2012-04-01 false Denial of capital gains treatment for gains on registration-required obligations not in registered form. 1.1287-1 Section 1.1287-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Special Rules for...

  10. Early Weight Gain, Linear Growth, and Mid-Childhood Blood Pressure: A Prospective Study in Project Viva.

    PubMed

    Perng, Wei; Rifas-Shiman, Sheryl L; Kramer, Michael S; Haugaard, Line K; Oken, Emily; Gillman, Matthew W; Belfort, Mandy B

    2016-02-01

    In recent years, the prevalence of hypertension and prehypertension increased markedly among children and adolescents, highlighting the importance of identifying determinants of elevated blood pressure early in life. Low birth weight and rapid early childhood weight gain are associated with higher future blood pressure. However, few studies have examined the timing of postnatal weight gain in relation to later blood pressure, and little is known regarding the contribution of linear growth. We studied 957 participants in Project Viva, an ongoing US prebirth cohort. We examined the relations of gains in body mass index z-score and length/height z-score during 4 early life age intervals (birth to 6 months, 6 months to 1 year, 1 to 2 years, and 2 to 3 years) with blood pressure during mid-childhood (6-10 years) and evaluated whether these relations differed by birth size. After accounting for confounders, each additional z-score gain in body mass index during birth to 6 months and 2 to 3 years was associated with 0.81 (0.15, 1.46) and 1.61 (0.33, 2.89) mm Hg higher systolic blood pressure, respectively. Length/height gain was unrelated to mid-childhood blood pressure, and there was no evidence of effect modification by birth size for body mass index or length/height z-score gain. Our findings suggest that more rapid gain in body mass index during the first 6 postnatal months and in the preschool years may lead to higher systolic blood pressure in mid-childhood, regardless of size at birth. Strategies to reduce accrual of excess adiposity during early life may reduce mid-childhood blood pressure, which may also impact adult blood pressure and cardiovascular health. PMID:26644238

  11. The Association Between Sleep Duration and Weight Gain in Adults: A 6-Year Prospective Study from the Quebec Family Study

    PubMed Central

    Chaput, Jean-Philippe; Desprs, Jean-Pierre; Bouchard, Claude; Tremblay, Angelo

    2008-01-01

    Study Objective: To investigate the relationship between sleep duration and subsequent body weight and fat gain. Design: Six-year longitudinal study. Setting: Community setting. Participants: Two hundred seventy-six adults aged 21 to 64 years from the Quebec Family Study. More than half of the sample is drawn from families with at least 1 parent and 1 offspring with a body mass index of 32 kg/m2 or higher. Measurements and Results: Body composition measurements and self-reported sleep duration were determined. Changes in adiposity indices were compared between short- (56 hours), average- (78 hours), and long- (910 hours) duration sleeper groups. After adjustment for age, sex, and baseline body mass index, short-duration sleepers gained 1.98 kg (95% confidence interval: 1.162.82) more and long-duration sleepers gained 1.58 kg (95% CI: 1.022.56) more than did average-duration sleepers over 6 years. Short- and long-duration sleepers were 35% and 25% more likely to experience a 5-kg weight gain, respectively, as compared with average-duration sleepers over 6 years. The risk of developing obesity was elevated for short- and long-duration sleepers as compared with average-duration sleepers, with 27% and 21% increases in risk, respectively. These associations remained significant after inclusion of important covariates and were not affected by adjustment for energy intake and physical activity participation. Conclusions: This study provides evidence that both short and long sleeping times predict an increased risk of future body weight and fat gain in adults. Hence, these results emphasize the need to add sleep duration to the panel of determinants that contribute to weight gain and obesity. Citation: Chaput JP; Desprs JP; Bouchard C; Tremblay A. The association between sleep duration and weight gain in adults: a 6-year prospective study from the Quebec Family Study. SLEEP 2008;31(4):517-523. PMID:18457239

  12. Elevation of SIPL1 (SHARPIN) Increases Breast Cancer Risk

    PubMed Central

    De Melo, Jason; Tang, Damu

    2015-01-01

    SIPL1 (Sharpin) or Sharpin plays a role in tumorigenesis. However, its involvement in breast cancer tumorigenesis remains largely unknown. To investigate this issue, we have systemically analyzed SIPL1 gene amplification and expression data available from Oncomine datasets, which were derived from 17 studies and contained approximately 20,000 genes, 3438 breast cancer cases, and 228 normal individuals. We found a SIPL1 gene amplification in invasive ductal breast cancers compared to normal breast tissues and a significant elevation of SIPL1 mRNA in breast cancers in comparison to non-tumor breast tissues. These results collectively reveal that increases in SIPL1 expression occur during breast cancer tumorigenesis. To further investigate this association, we observed increases in the SIPL1 gene and mRNA in the breast cancer subtypes of estrogen receptor (ER)+, progesterone receptor (PR)+, HER2+, or triple negative. Additionally, a gain of the SIPL1 gene correlated with breast cancer grade and the levels of SIPL1 mRNA associated with both breast cancer stages and grades. Elevation of SIPL1 gene copy and mRNA is linked to a decrease in patient survival, especially for those with PR+, ER+, or HER2- breast cancers. These results are supported by our analysis of SIPL1 protein expression using a tissue microarray containing 224 breast cancer cases, in which higher levels of SIPL1 relate to ER+ and PR+ tumors and AKT activation. Furthermore, we were able to show that progesterone significantly reduced SIPL1 mRNA and protein expression in MCF7 cells. As progesterone enhances breast cancer tumorigenesis in a context dependent manner, inhibition of SIPL1 expression may contribute to progesterone's non-tumorigenic function which might be countered by SIPL1 upregulation. Taken together, we demonstrate a positive correlation of SIPL1 with BC tumorigenesis. PMID:25992689

  13. Temporal Gain Correction for X-ray Calorimeter Spectrometers

    NASA Astrophysics Data System (ADS)

    Porter, F. S.; Chiao, M. P.; Eckart, M. E.; Fujimoto, R.; Ishisaki, Y.; Kelley, R. L.; Kilbourne, C. A.; Leutenegger, M. A.; McCammon, D.; Mitsuda, K.; Sawada, M.; Szymkowiak, A. E.; Takei, Y.; Tashiro, M.; Tsujimoto, M.; Watanabe, T.; Yamada, S.

    2016-01-01

    Calorimetric X-ray detectors are very sensitive to their environment. The boundary conditions can have a profound effect on the gain including heat sink temperature, the local radiation temperature, bias, and the temperature of the readout electronics. Any variation in the boundary conditions can cause temporal variations in the gain of the detector and compromise both the energy scale and the resolving power of the spectrometer. Most production X-ray calorimeter spectrometers, both on the ground and in space, have some means of tracking the gain as a function of time, often using a calibration spectral line. For small gain changes, a linear stretch correction is often sufficient. However, the detectors are intrinsically non-linear and often the event analysis, i.e., shaping, optimal filters etc., add additional non-linearity. Thus for large gain variations or when the best possible precision is required, a linear stretch correction is not sufficient. Here, we discuss a new correction technique based on non-linear interpolation of the energy-scale functions. Using Astro-H/SXS calibration data, we demonstrate that the correction can recover the X-ray energy to better than 1 part in 104 over the entire spectral band to above 12 keV even for large-scale gain variations. This method will be used to correct any temporal drift of the on-orbit per-pixel gain using on-board calibration sources for the SXS instrument on the Astro-H observatory.

  14. Gain Scheduling for the Orion Launch Abort Vehicle Controller

    NASA Technical Reports Server (NTRS)

    McNamara, Sara J.; Restrepo, Carolina I.; Madsen, Jennifer M.; Medina, Edgar A.; Proud, Ryan W.; Whitley, Ryan J.

    2011-01-01

    One of NASAs challenges for the Orion vehicle is the control system design for the Launch Abort Vehicle (LAV), which is required to abort safely at any time during the atmospheric ascent portion of ight. The focus of this paper is the gain design and scheduling process for a controller that covers the wide range of vehicle configurations and flight conditions experienced during the full envelope of potential abort trajectories from the pad to exo-atmospheric flight. Several factors are taken into account in the automation process for tuning the gains including the abort effectors, the environmental changes and the autopilot modes. Gain scheduling is accomplished using a linear quadratic regulator (LQR) approach for the decoupled, simplified linear model throughout the operational envelope in time, altitude and Mach number. The derived gains are then implemented into the full linear model for controller requirement validation. Finally, the gains are tested and evaluated in a non-linear simulation using the vehicles ight software to ensure performance requirements are met. An overview of the LAV controller design and a description of the linear plant models are presented. Examples of the most significant challenges with the automation of the gain tuning process are then discussed. In conclusion, the paper will consider the lessons learned through out the process, especially in regards to automation, and examine the usefulness of the gain scheduling tool and process developed as applicable to non-Orion vehicles.

  15. Gain properties of dye-doped polymer thin films

    NASA Astrophysics Data System (ADS)

    Gozhyk, I.; Boudreau, M.; Haghighi, H. Rabbani; Djellali, N.; Forget, S.; Chénais, S.; Ulysse, C.; Brosseau, A.; Pansu, R.; Audibert, J.-F.; Gauvin, S.; Zyss, J.; Lebental, M.

    2015-12-01

    Hybrid pumping appears as a promising compromise in order to reach the much coveted goal of an electrically pumped organic laser. In such configuration the organic material is optically pumped by an electrically pumped inorganic device on a chip. This engineering solution requires therefore an optimization of the organic gain medium under optical pumping. Here, we report a detailed study of the gain features of dye-doped polymer thin films. In particular we introduce the gain efficiency K , in order to facilitate comparison between different materials and experimental conditions. The gain efficiency was measured with a variety of experimental methods (pump-probe amplification, variable stripe length method, laser thresholds) in order to study several factors which modify the actual gain of a layer, namely the confinement factor, the pump polarization, the molecular anisotropy, and the re-absorption. For instance, for a 600-nm-thick 5-wt % DCM doped poly(methyl methacrylate) (PMMA) layer, the different experimental approaches give a consistent value of K ≃ 80 -cm MW-1 . On the contrary, the usual model predicting the gain from the characteristics of the material leads to an overestimation by two orders of magnitude, which raises a serious problem in the design of actual devices. In this context, we demonstrate the feasibility to infer the gain efficiency from the laser threshold of well-calibrated devices. Temporal measurements at the picosecond scale were carried out to support the analysis.

  16. Modifiable predictors associated with having a gestational weight gain goal.

    PubMed

    Tovar, Alison; Guthrie, Lauren B; Platek, Deborah; Stuebe, Alison; Herring, Sharon J; Oken, Emily

    2011-10-01

    The goal of this paper was to determine predictors of having a weight gain goal in early pregnancy. In 2008, we administered a 48-item survey to 249 pregnant women attending obstetric visits. We examined predictors of women having a goal concordant or discordant with 1990 Institute of Medicine (IOM) guidelines, vs. no goal, using binary and multinomial logistic regression. Of the 292 respondents, 116 (40%) had no gestational weight gain goal, 112 (39%) had a concordant goal and 61 (21%) had a goal discordant with IOM guidelines. Predictors of a guideline-concordant goal, vs. no goal, included sugar sweetened beverage consumption < vs. ? 1 serving per week (OR = 2.4, 95%CI: 1.1, 5.7), physical activity ? vs. <2.5 h per week (OR = 3.6, 95%CI: 1.7, 7.5), agreeing that 'I tried to keep weight down not to look pregnant' (OR = 14.3, 95%CI: 1.4, 140.5). Other predictors only of having a discordant goal (vs. no goal) included agreeing that 'as long as I am eating well, I don't care how much I gain' (OR = 0.3, 95%CI: 0.2, 0.8) and agreeing that 'if I gain too much weight one month, I try to keep from gaining the next' (OR = 4.1, 95%CI: 1.6, 10.4). Women whose doctors recommended weight gains consistent with IOM guidelines were more likely to have a concordant goal (vs. no goal) (OR = 5.3, 95%CI: 1.5, 18.6). Engaging in healthy behaviors and having health providers offer IOM weight gain recommendations may increase the likelihood of having a concordant gestational weight gain goal, which, in turn, is predictive of actual weight gains that fall within IOM guidelines. PMID:20711804

  17. Low Gestational Weight Gain Skews Human Sex Ratios towards Females

    PubMed Central

    Navara, Kristen J.

    2014-01-01

    Background Human males are more vulnerable to adverse conditions than females starting early in gestation and continuing throughout life, and previous studies show that severe food restriction can influence the sex ratios of human births. It remains unclear, however, whether subtle differences in caloric intake during gestation alter survival of fetuses in a sex-specific way. I hypothesized that the ratio of male to female babies born should vary with the amount of weight gained during gestation. I predicted that women who gain low amounts of weight during gestation should produce significantly more females, and that, if gestational weight gain directly influences sex ratios, fetal losses would be more likely to be male when women gain inadequate amounts of weight during pregnancy. Methods I analyzed data collected from over 68 million births over 23 years to test for a relationship between gestational weight gain and natal sex ratios, as well as between gestational weight gain and sex ratios of fetal deaths at five gestational ages. Results Gestational weight gain and the proportion of male births were positively correlated; a lower proportion of males was produced by women who gained less weight and this strong pattern was exhibited in four human races. Further, sex ratios of fetal losses at 6 months of gestation were significantly male-biased when mothers had gained low amounts of weight during pregnancy, suggesting that low caloric intake during early fetal development can stimulate the loss of male fetuses. Conclusion My data indicate that human sex ratios change in response to resource availability via sex-specific fetal loss, and that a pivotal time for influences on male survival is early in fetal development, at 6 months of gestation. PMID:25493647

  18. Metformin for Lithium-induced Weight Gain: A Case Report.

    PubMed

    Praharaj, Samir Kumar

    2016-02-29

    Lithium is the first line treatment for maintenance treatment of bipolar disorder. Among the long term adverse effects, weight gain is likely to affect a subset of patients. There is no specific guideline for the treatment of lithium-induced weight gain. We report a young male with bipolar disorder who had significant weight gain with lithium (25 kg), which responded to metformin treatment at 500 mg twice daily. The proposed mechanism of weight lowering effect of metformin includes changes in hypothalamic physiology, including leptin and insulin sensitivity, as well as circadian rhythm changes affecting food intake, regulation of fat oxidation and storage in liver, skeletal muscle, and adipose tissue. PMID:26792047

  19. LPV Controller Interpolation for Improved Gain-Scheduling Control Performance

    NASA Technical Reports Server (NTRS)

    Wu, Fen; Kim, SungWan

    2002-01-01

    In this paper, a new gain-scheduling control design approach is proposed by combining LPV (linear parameter-varying) control theory with interpolation techniques. The improvement of gain-scheduled controllers can be achieved from local synthesis of Lyapunov functions and continuous construction of a global Lyapunov function by interpolation. It has been shown that this combined LPV control design scheme is capable of improving closed-loop performance derived from local performance improvement. The gain of the LPV controller will also change continuously across parameter space. The advantages of the newly proposed LPV control is demonstrated through a detailed AMB controller design example.

  20. Simulation of semiconductor nanowire photodetectors with high photoconductive gain

    NASA Astrophysics Data System (ADS)

    Cao, Hanqing; Lai, Jianjun; Zhu, Ji; Li, Hongwei; Chen, Changhong; Huang, Ying

    2015-10-01

    In this paper, first we simulate the light absorption of individual cylindrical nanowire with the diameter ranging from 100 to 300 nm, it is found that the absorption peak has a red-shift along with the increased diameter. Then some numerical simulations have been done to elucidate the high gain mechanism and investigate the dependence of photoconductive gain on various parameters, such as doping, surface state density, and structure. The results show that optimizing these parameters appropriately can lead photoconductive gain up to 106, and give a reliable guiding to the actual device design.

  1. Symmetry breaking and multipeaked solitons in inhomogeneous gain landscapes

    SciTech Connect

    Kartashov, Yaroslav V.; Vysloukh, Victor A.; Konotop, Vladimir V.

    2011-04-15

    We address one-dimensional soliton formation in a cubic nonlinear medium with two-photon absorption and transversally inhomogeneous gain landscape consisting of a single or several amplifying channels. Existence of the solitons requires certain threshold gain while the properties of solitons strongly depend on whether the number of the amplifying channels is odd or even. In the former case, an increase of the gain leads to symmetry breaking, which occurs through the pitchfork bifurcation, and to emergence of a single or several coexisting stable asymmetric modes. In the case of an even number of amplifying channels, we have found only asymmetric stable states.

  2. Fresnel reflection from a cavity with net roundtrip gain

    SciTech Connect

    Mansuripur, Tobias S.; Mansuripur, Masud

    2014-03-24

    A planewave incident on an active etalon with net roundtrip gain may be expected to diverge in field amplitude, yet applying the Fresnel formalism to Maxwell's equations admits a convergent solution. We describe this solution mathematically and provide additional insight by demonstrating the response of such a cavity to an incident beam of light. Cavities with net roundtrip gain have often been overlooked in the literature, and a clear understanding of their behavior yields insight to negative refraction in nonmagnetic media, a duality between loss and gain, amplified total internal reflection, and the negative-index lens.

  3. Gain enhancement of microstrip antennas with overlaying parasitic directors

    NASA Technical Reports Server (NTRS)

    Lee, R. Q.; Lee, K. F.

    1988-01-01

    An experimental study of gain enhancement in microstrip antennas using identical parasitic patch directors is reported. The results indicate that, with two overlying parasitic directors, the gain of a rectangular microstrip antenna is enhanced from 4.7 dB to 10.6 dB, while the 3 dB beamwidth is reduced from 103 deg to 30 deg for the E-plane and from 70 deg to 35 deg for the H-plane. The three-layer electromagnetically coupled patch antenna exhibits similar antenna characteristics to those of the Yagi array, with over 120 dB gain and with about 1 percent bandwidth.

  4. Achieving improved cycle efficiency via pressure gain combustors

    SciTech Connect

    Gemmen, R.S.; Janus, M.C.; Richards, G.A.; Norton, T.S.; Rogers, W.A.

    1995-04-01

    As part of the Department of Energy`s Advanced Gas Turbine Systems Program, an investigation is being performed to evaluate ``pressure gain`` combustion systems for gas turbine applications. This paper presents experimental pressure gain and pollutant emission data from such combustion systems. Numerical predictions for certain combustor geometries are also presented. It is reported that for suitable aerovalved pulse combustor geometries studied experimentally, an overall combustor pressure gain of nearly 1 percent can be achieved. It is also shown that for one combustion system operating under typical gas turbine conditions, NO{sub x} and CO emmissions, are about 30 ppmv and 8 ppmv, respectively.

  5. Gain saturation in semiconductor lasers - Theory and experiment

    NASA Technical Reports Server (NTRS)

    Kasemset, D.; Fonstad, C. G., Jr.

    1982-01-01

    The semiconductor stimulated gain saturation model of Zee has been extended using reasonable approximations to obtain an analytical solution for the gain saturation process in PbSnTe and to determine the limit to single mode power directly from the gain expression, the intraband relaxation time, and device and material parameters. The theoretical results are compared with experimental observations for single transverse mode cavity narrow stripe buried heterostructure PbSnTe lasers. Those results are interpreted in terms of an intraband relaxation time on the order of 2 x 10 to the -12th s in the temperature range 20-80 K.

  6. Proton and gamma ray induced gain degradation in bipolar transistor

    NASA Astrophysics Data System (ADS)

    Kulkarni, S. R.; Sarma, A.; Joshi, G. R.; Ravindra, M.; Damle, R.

    2003-09-01

    This paper describes the results of the effect of 24 MeV proton and (CO)-C-60 gamma-irradiation on the collector characteristic., and forward current gain of commercial bipolar transistor (npn 2N2219A). The transistor has been exposed to these radiations in the biased condition and the collector characteristics and forward current gain have been measured as a function of proton fluence and gamma-dose. The observation is that both the proton and gamma-irradiation induce significant gain degradation in the transistor. The results are discussed in terms of displacement damage produced by energetic protons and gamma-radiation in the bulk of the semiconductor.

  7. Figuring gain loss in dielectric loaded rectangular horns

    NASA Astrophysics Data System (ADS)

    Kumar, A.

    1987-06-01

    A method for estimating the loss of gain in dielectric loaded horns is described. The relation between dielectric thickness in 12 GHz and 14 GHz bands and gain is studied. Complex permittivity for the glue used between the metal and dielectric slab in flight horns and of the dielectric slab are calculated. Changes in the antenna attenuation as a function of complex permittivity are examined. The equation for calculating the dielectric loss is given. The calculated loss in gain due to the dielectric material is about 0.27 dB and 0.18 dB in 12 GHz and 14 GHz bands.

  8. Inhomogeneous Gain Saturation in EDF: Experiment and Modeling

    NASA Astrophysics Data System (ADS)

    Peretti, Romain; Jacquier, Bernard; Boivin, David; Burov, Ekaterina; Jurdyc, Anne-Marie

    2011-05-01

    Erbium-Doped Fiber Amplifiers can present holes in spectral gain in Wavelength Division Multiplexing operation. The origin of this inhomogeneous saturation behavior is still a subject of controversy. In this paper we present both an experimental methods and a gain's model. Our experimental method allow us to measure the first homogeneous linewidth of the 1.5 $\\mu$m erbium emission with gain spectral hole burning consistently with the other measurement in the literature and the model explains the differences observed in literature between GSHB and other measurement methods.

  9. Troponin elevation after black widow spider envenomation.

    PubMed

    Bush, Sean P; Davy, J Veeran

    2015-09-01

    Black widow spider envenomation generally results in self-limiting pain that can be treated in the emergency department (ED) with analgesics and benzodiazepines, usually with no further intervention. Occasionally, a patient has to be admitted or treated with antivenom for refractory pain or a venom-induced complication. We present the case of an 84-year-old man who presented to our ED with chest pain and dyspnea after being bitten on the foot by a western black widow spider (Lactrodectus hesperus). His initial cardiac troponin I (cTnI) was elevated at 0.07 ng/ml and continued to rise to a peak of 0.17 ng/ml. He also had rhabdomyolysis, another uncommon complication of black widow envenomation. An elevated cTnI generally signifies myocardial injury and is rarely seen after black widow envenomation. We discuss the possible etiologies for an elevated cardiac biomarker, in this context, and review potentially serious complications of widow spider envenomation presenting with chest symptoms and an elevated cardiac biomarker. PMID:26206067

  10. 77 FR 51743 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-27

    ... provides corrections to that table, to be used in lieu of the information published at 75 FR 78654. The... for the contents in those buildings. Correction In the proposed rule published at 75 FR 78654, in the... modified elevations, and communities affected for the City of Newport News, Virginia. Specifically,...

  11. 77 FR 74142 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-13

    ... buildings. Correction In the proposed rule published at 75 FR 29238 and 76 FR 62006, in the May 25, 2010 and... elevations, and communities affected for Iron County, Utah, and Incorporated Areas. Specifically, it... and Water Canyon. DATES: Comments are to be submitted on or before March 13, 2013. ADDRESSES: You...

  12. 78 FR 29654 - Final Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-21

    ... 12866 of September 30, 1993, Regulatory Planning and Review, 58 FR 51735. Executive Order 13132... et seq.; Reorganization Plan No. 3 of 1978, 3 CFR, 1978 Comp., p. 329; E.O. 12127, 44 FR 19367, 3 CFR... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Final Flood Elevation Determinations...

  13. Climatic change at high elevation sites

    SciTech Connect

    Dr. Henry F. Diaz

    1998-07-23

    A Workshop on climatic change at high elevation sites was held September 11-15, 1995 in Wengen, Switzerland. The meeting was sponsored by both U.S. (Department of Energy, National Science Foundation and National Oceanic & Atmospheric Administration) and European (Swiss National Science Foundation, European Science Foundation, Swiss Federal Institute of Technology) agencies. The goals of the workshop were to (1) focus the attention of the world climate community on the existence of unique high elevation geophysical records around the world, (2) highlight the value of these observing sites for climate change detection efforts and to help insure the continued support of governments and of relevant institutions in the maintenance of these high elevation data gathering efforts, (3) discuss and evaluate climatic trends that may be present in these records, and to compare the information with available paleoenvironmental records of glaciers, tree-rings and varved sediments from the alpine zones, and (4) discuss and evaluate information about elevational differences in current and projected greenhouse-gas induced climatic changes in coupled General Circulation Models.

  14. ELEVATION DATA FOR OREGON AND WASHINGTON

    EPA Science Inventory

    The WA 1:24,000 scale data have an elevation at approx. every 30 meters. The 1:250,000 scale data are gathered at intervals of approx. every 85 meters along the ground. These data may be used in the generation of graphics such as isometric projections displaying slope, directio...

  15. 75 FR 55527 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-13

    ... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations AGENCY: Federal Emergency Management Agency, DHS. ACTION: Proposed rule. SUMMARY: Comments are requested on the... locations in the table below. The BFEs and modified BFEs are a part of the floodplain management...

  16. 76 FR 8330 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-14

    ... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations Correction In proposed rule document 2011-1061, appearing on pages 3590-3595, in the issue of Thursday, January 20, 2011, make the following correction: Sec. 67.4 On page 3592 in Sec. 67.4, under ADDRESSES,...

  17. 77 FR 20999 - Final Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-09

    ... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Final Flood Elevation Determinations Correction In rule document 2011-15507 appearing on pages 36373-36384 in the issue of June 22, 2011, and C1-2011-15507 appearing on page 61279 in the issue of October 4, 2011, make the following corrections: Sec....

  18. 76 FR 54721 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-02

    ... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations Correction In proposed rule document 2011-20866 beginning on page 50960 in the issue of Wednesday, August 17, 2011, make the following correction: Sec. 67.4 On page 50962, in the eleventh line below the...

  19. Automated building extraction using dense elevation matrices

    NASA Astrophysics Data System (ADS)

    Bendett, A. A.; Rauhala, Urho A.; Pearson, James J.

    1997-02-01

    The identification and measurement of buildings in imagery is important to a number of applications including cartography, modeling and simulation, and weapon targeting. Extracting large numbers of buildings manually can be time- consuming and expensive, so the automation of the process is highly desirable. This paper describes and demonstrates such an automated process for extracting rectilinear buildings from stereo imagery. The first step is the generation of a dense elevation matrix registered to the imagery. In the examples shown, this was accomplished using global minimum residual matching (GMRM). GMRM automatically removes y- parallax from the stereo imagery and produces a dense matrix of x-parallax values which are proportional to the local elevation, and, of course, registered to the imagery. The second step is to form a joint probability distribution of the image gray levels and the corresponding height values from the elevation matrix. Based on the peaks of that distribution, the area of interest is segmented into feature and non-feature areas. The feature areas are further refined using length, width and height constraints to yield promising building hypotheses with their corresponding vertices. The gray shade image is used in the third step to verify the hypotheses and to determine precise edge locations corresponding to the approximate vertices and satisfying appropriate orthogonality constraints. Examples of successful application of this process to imagery are presented, and extensions involving the use of dense elevation matrices from other sources are possible.

  20. 77 FR 21476 - Final Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-10

    ...Base (1% annual-chance) Flood Elevations (BFEs) and modified BFEs are made final for the communities listed below. The BFEs and modified BFEs are the basis for the floodplain management measures that each community is required either to adopt or to show evidence of being already in effect in order to qualify or remain qualified for participation in the National Flood Insurance Program...

  1. 76 FR 46716 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-03

    ... provides corrections to that table, to be used in lieu of the information published at 75 FR 31373. The... rule published at 75 FR 31373, in the June 3, 2010, issue of the Federal Register, FEMA published a... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations...

  2. 75 FR 23595 - Final Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-04

    ... and Review, 58 FR 51735. Executive Order 13132, Federalism. This final rule involves no policies that... 1978, 3 CFR, 1978 Comp., p. 329; E.O. 12127, 44 FR 19367, 3 CFR, 1979 Comp., p. 376. Sec. 67.11 0 2... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Final Flood Elevation Determinations...

  3. 76 FR 13570 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-14

    ... notice provides corrections to that table, to be used in lieu of the information published at 74 FR 47169... contents in those buildings. Correction In the proposed rule published at 74 FR 47169, in the September 15... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations...

  4. 78 FR 5738 - Final Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-28

    ... 12866 of September 30, 1993, Regulatory Planning and Review, 58 FR 51735. Executive Order 13132... et seq.; Reorganization Plan No. 3 of 1978, 3 CFR, 1978 Comp., p. 329; E.O. 12127, 44 FR 19367, 3 CFR... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Final Flood Elevation Determinations...

  5. 75 FR 14091 - Final Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-24

    ... and Review, 58 FR 51735. Executive Order 13132, Federalism. This final rule involves no policies that... 1978, 3 CFR, 1978 Comp., p. 329; E.O. 12127, 44 FR 19367, 3 CFR, 1979 Comp., p. 376. Sec. 67.11 0 2... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Final Flood Elevation Determinations...

  6. 76 FR 12308 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-07

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations Correction In proposed rule document 2011-2281 beginning on page 5769 in the issue of Wednesday, February...

  7. 77 FR 18766 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-28

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations... located on the stream reach between the referenced locations above. Please refer to the revised...

  8. 75 FR 3885 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-25

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations... locations above. Please refer to the revised Flood Insurance Rate Map located at the community...

  9. 78 FR 33991 - Final Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-06

    ... 12866 of September 30, 1993, Regulatory Planning and Review, 58 FR 51735. Executive Order 13132... et seq.; Reorganization Plan No. 3 of 1978, 3 CFR, 1978 Comp., p. 329; E.O. 12127, 44 FR 19367, 3 CFR... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Final Flood Elevation Determinations...

  10. 76 FR 50443 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-15

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations Correction In proposed rule document 2011-16640 appearing on pages 39063 through 39067 in the issue...

  11. 76 FR 43966 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-22

    ... provides corrections to that table, to be used in lieu of the information published at 75 FR 31342. The... rule published at 75 FR 31342, in the June 3, 2010, issue of the Federal Register, FEMA published a... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations...

  12. 77 FR 46980 - Final Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-07

    ... Executive Order 12866 of September 30, 1993, Regulatory Planning and Review, 58 FR 51735. Executive Order....C. 4001 et seq.; Reorganization Plan No. 3 of 1978, 3 CFR, 1978 Comp., p. 329; E.O. 12127, 44 FR... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Final Flood Elevation Determinations...

  13. 77 FR 6980 - Final Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-10

    ... Executive Order 12866 of September 30, 1993, Regulatory Planning and Review, 58 FR 51735. Executive Order....C. 4001 et seq.; Reorganization Plan No. 3 of 1978, 3 CFR, 1978 Comp., p. 329; E.O. 12127, 44 FR... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Final Flood Elevation Determinations...

  14. 76 FR 46715 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-03

    ... provides corrections to that table, to be used in lieu of the information published at 75 FR 29290. The... rule published at 75 FR 29290, in the May 25, 2010, issue of the Federal Register, FEMA published a... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations...

  15. 75 FR 3171 - Final Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-20

    ...Base (1% annual-chance) Flood Elevations (BFEs) and modified BFEs are made final for the communities listed below. The BFEs and modified BFEs are the basis for the floodplain management measures that each community is required either to adopt or to show evidence of being already in effect in order to qualify or remain qualified for participation in the National Flood Insurance Program...

  16. 75 FR 59989 - Final Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-29

    ...Base (1% annual-chance) Flood Elevations (BFEs) and modified BFEs are made final for the communities listed below. The BFEs and modified BFEs are the basis for the floodplain management measures that each community is required either to adopt or to show evidence of being already in effect in order to qualify or remain qualified for participation in the National Flood Insurance Program...

  17. 77 FR 26959 - Final Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-08

    ...Base (1% annual-chance) Flood Elevations (BFEs) and modified BFEs are made final for the communities listed below. The BFEs and modified BFEs are the basis for the floodplain management measures that each community is required either to adopt or to show evidence of being already in effect in order to qualify or remain qualified for participation in the National Flood Insurance Program...

  18. Elevated fetal steroidogenic activity in autism.

    PubMed

    Baron-Cohen, S; Auyeung, B; Nrgaard-Pedersen, B; Hougaard, D M; Abdallah, M W; Melgaard, L; Cohen, A S; Chakrabarti, B; Ruta, L; Lombardo, M V

    2015-03-01

    Autism affects males more than females, giving rise to the idea that the influence of steroid hormones on early fetal brain development may be one important early biological risk factor. Utilizing the Danish Historic Birth Cohort and Danish Psychiatric Central Register, we identified all amniotic fluid samples of males born between 1993 and 1999 who later received ICD-10 (International Classification of Diseases,10thRevision) diagnoses of autism, Asperger syndromeorPDD-NOS (pervasive developmental disorder not otherwise specified) (n=128) compared withmatched typically developing controls. Concentration levels of ?4 sex steroids (progesterone, 17?-hydroxy-progesterone, androstenedioneand testosterone) and cortisol were measured with liquid chromatography tandemmass spectrometry. All hormones were positively associated with each other and principal componentanalysis confirmed that one generalized latent steroidogenic factor was driving much of the variation in the data. The autism group showed elevations across all hormones on this latent generalized steroidogenic factor (Cohen's d=0.37, P=0.0009) and this elevation was uniform across ICD-10 diagnostic label. These results provide the first direct evidence of elevated fetal steroidogenic activity in autism. Such elevations may be important as epigenetic fetal programming mechanisms and may interact with other important pathophysiological factors in autism. PMID:24888361

  19. 77 FR 49373 - Final Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-16

    ... 12866 of September 30, 1993, Regulatory Planning and Review, 58 FR 51735. Executive Order 13132... et seq.; Reorganization Plan No. 3 of 1978, 3 CFR, 1978 Comp., p. 329; E.O. 12127, 44 FR 19367, 3 CFR... Elevation in meters (MSL) Modified Chicot County, Arkansas, and Incorporated Areas Docket No.:...

  20. Elevation correction factor for absolute pressure measurements

    NASA Technical Reports Server (NTRS)

    Panek, Joseph W.; Sorrells, Mark R.

    1996-01-01

    With the arrival of highly accurate multi-port pressure measurement systems, conditions that previously did not affect overall system accuracy must now be scrutinized closely. Errors caused by elevation differences between pressure sensing elements and model pressure taps can be quantified and corrected. With multi-port pressure measurement systems, the sensing elements are connected to pressure taps that may be many feet away. The measurement system may be at a different elevation than the pressure taps due to laboratory space or test article constraints. This difference produces a pressure gradient that is inversely proportional to height within the interface tube. The pressure at the bottom of the tube will be higher than the pressure at the top due to the weight of the tube's column of air. Tubes with higher pressures will exhibit larger absolute errors due to the higher air density. The above effect is well documented but has generally been taken into account with large elevations only. With error analysis techniques, the loss in accuracy from elevation can be easily quantified. Correction factors can be applied to maintain the high accuracies of new pressure measurement systems.

  1. Elevated fetal steroidogenic activity in autism

    PubMed Central

    Baron-Cohen, S; Auyeung, B; Nrgaard-Pedersen, B; Hougaard, D M; Abdallah, M W; Melgaard, L; Cohen, A S; Chakrabarti, B; Ruta, L; Lombardo, M V

    2015-01-01

    Autism affects males more than females, giving rise to the idea that the influence of steroid hormones on early fetal brain development may be one important early biological risk factor. Utilizing the Danish Historic Birth Cohort and Danish Psychiatric Central Register, we identified all amniotic fluid samples of males born between 1993 and 1999 who later received ICD-10 (International Classification of Diseases,10thRevision) diagnoses of autism, Asperger syndromeorPDD-NOS (pervasive developmental disorder not otherwise specified) (n=128) compared withmatched typically developing controls. Concentration levels of ?4 sex steroids (progesterone, 17?-hydroxy-progesterone, androstenedioneand testosterone) and cortisol were measured with liquid chromatography tandemmass spectrometry. All hormones were positively associated with each other and principal componentanalysis confirmed that one generalized latent steroidogenic factor was driving much of the variation in the data. The autism group showed elevations across all hormones on this latent generalized steroidogenic factor (Cohen's d=0.37, P=0.0009) and this elevation was uniform across ICD-10 diagnostic label. These results provide the first direct evidence of elevated fetal steroidogenic activity in autism. Such elevations may be important as epigenetic fetal programming mechanisms and may interact with other important pathophysiological factors in autism. PMID:24888361

  2. 76 FR 19018 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-06

    ... FR 19367, 3 CFR, 1979 Comp., p. 376. Sec. 67.4 2. The tables published under the authority of Sec. 67... SECURITY Federal Emergency Management Agency 44 CFR Part 67 Docket ID FEMA-2011-0002 Proposed Flood Elevation Determinations AGENCY: Federal Emergency Management Agency, DHS. ACTION: Proposed rule....

  3. 21 CFR 890.3930 - Wheelchair elevator.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Wheelchair elevator. 890.3930 Section 890.3930 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Prosthetic Devices § 890.3930...

  4. 21 CFR 890.3930 - Wheelchair elevator.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Wheelchair elevator. 890.3930 Section 890.3930 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Prosthetic Devices § 890.3930...

  5. 21 CFR 890.3930 - Wheelchair elevator.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Wheelchair elevator. 890.3930 Section 890.3930 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Prosthetic Devices § 890.3930...

  6. 21 CFR 890.3930 - Wheelchair elevator.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Wheelchair elevator. 890.3930 Section 890.3930 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Prosthetic Devices § 890.3930...

  7. 21 CFR 890.3930 - Wheelchair elevator.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Wheelchair elevator. 890.3930 Section 890.3930 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Prosthetic Devices § 890.3930...

  8. 76 FR 272 - Final Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-04

    ...Base (1% annual-chance) Flood Elevations (BFEs) and modified BFEs are made final for the communities listed below. The BFEs and modified BFEs are the basis for the floodplain management measures that each community is required either to adopt or to show evidence of being already in effect in order to qualify or remain qualified for participation in the National Flood Insurance Program...

  9. Advanced composite elevator for Boeing 727 aircraft

    NASA Technical Reports Server (NTRS)

    1978-01-01

    Detail design activities are reported for a program to develop an advanced composites elevator for the Boeing 727 commercial transport. Design activities include discussion and results of the ancillary test programs, sustaining efforts, weight status, manufacturing producibility studies, quality assurance development, and production status.

  10. Low Elevated Lead Levels and Mental Retardation.

    ERIC Educational Resources Information Center

    Marlowe, Mike; And Others

    The relationship between low elevated lead absorption and mild mental retardation was investigated in 40 rural children (preschool to grade 12) without demonstrable cause for their retardation. Trace mineral analysis of hair samples from Ss and a control group (N=20) indicated the mean hair lead concentrations for the retarded Ss were considerably

  11. 76 FR 61070 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-03

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency 44 CFR Part 67 Proposed Flood Elevation Determinations Correction In proposed rule document 2010-31549 appearing on pages 78664-78666 in the issue of December...

  12. Satellite Placement Using a Partial Space Elevator

    NASA Astrophysics Data System (ADS)

    Woo, Pamela

    The space elevator has been proposed as an alternate method for launching cargo into space. However, the construction of such a structure requires a material much stronger than any currently in existence. Instead, a partial elevator is considered for satellite placement. In the first part of the thesis, the fundamentals of very long tethered systems are studied. From static analysis on a simple two-body system, it is demonstrated that an assumption made in the conventional analysis does not apply to very long tethered systems. For a uniform tether, the axial stress distribution is obtained. Following the Lagrangian approach, the equations of motion governing the planar librations of a multi-body tethered system are derived. From a linearization of these equations, the libration frequencies are found. Then, by solving the nonlinear equations numerically, the responses to various changes in the system parameters are determined. In the second part of the thesis, the use of a partial elevator in satellite placement is studied. In the case of single climber transit, residual librations occur, which alter the shape and size of the orbit of a satellite launched from the climber. An approach using two climbers is investigated in order to decrease the residual libration and thereby reduce orbit placement errors. Also, some energy calculations are done to determine whether the partial elevator offers significant advantages.

  13. 76 FR 3524 - Final Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-20

    ...Base (1% annual-chance) Flood Elevations (BFEs) and modified BFEs are made final for the communities listed below. The BFEs and modified BFEs are the basis for the floodplain management measures that each community is required either to adopt or to show evidence of being already in effect in order to qualify or remain qualified for participation in the National Flood Insurance Program...

  14. 75 FR 59634 - Final Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-28

    ...Base (1% annual-chance) Flood Elevations (BFEs) and modified BFEs are made final for the communities listed below. The BFEs and modified BFEs are the basis for the floodplain management measures that each community is required either to adopt or to show evidence of being already in effect in order to qualify or remain qualified for participation in the National Flood Insurance Program...

  15. Low Elevated Lead Levels and Mental Retardation.

    ERIC Educational Resources Information Center

    Marlowe, Mike; And Others

    The relationship between low elevated lead absorption and mild mental retardation was investigated in 40 rural children (preschool to grade 12) without demonstrable cause for their retardation. Trace mineral analysis of hair samples from Ss and a control group (N=20) indicated the mean hair lead concentrations for the retarded Ss were considerably…

  16. High temperature and wavelength dependence of avalanche gain of AlAsSb avalanche photodiodes.

    PubMed

    Sandall, Ian C; Xie, Shiyu; Xie, Jingjing; Tan, Chee Hing

    2011-11-01

    The evolution of the dark currents and breakdown at elevated temperatures of up to 450 ?K are studied using thin AlAsSb avalanche regions. While the dark currents increase rapidly as the temperature is increased, the avalanche gain is shown to only have a weak temperature dependence. Temperature coefficients of breakdown voltage of 0.93 and 1.93 ?mV/K were obtained from the diodes of 80 and 230 ?nm avalanche regions (i-regions), respectively. These values are significantly lower than for other available avalanche materials at these temperatures. The wavelength dependence of multiplication characteristics of AlAsSb p-i-n diodes has also been investigated, and it was found that the ionization coefficients for electrons and holes are comparable within the electric field and wavelength ranges measured. PMID:22048393

  17. Increased epigenetic alterations at the promoters of transcriptional regulators following inadequate maternal gestational weight gain

    PubMed Central

    Kawai, Tomoko; Yamada, Takahiro; Abe, Kosei; Okamura, Kohji; Kamura, Hiromi; Akaishi, Rina; Minakami, Hisanori; Nakabayashi, Kazuhiko; Hata, Kenichiro

    2015-01-01

    Epigenetic modifications are thought to serve as a memory of exposure to in utero environments. However, few human studies have investigated the associations between maternal nutritional conditions during pregnancy and epigenetic alterations in offspring. In this study, we report genome-wide methylation profiles for 33 postpartum placentas from pregnancies of normal and foetal growth restriction with various extents of maternal gestational weight gain. Epigenetic alterations accumulate in the placenta under adverse in utero environments, as shown by application of Smirnov-Grubbs outlier test. Moreover, hypermethylation occurs frequently at the promoter regions of transcriptional regulator genes, including polycomb targets and zinc-finger genes, as shown by annotations of the genomic and functional features of loci with altered DNA methylation. Aberrant epigenetic modifications at such developmental regulator loci, if occurring in foetuses as well, will elevate the risk of developing various diseases, including metabolic and mental disorders, later in life. PMID:26415774

  18. Hurricane Wilma's impact on overall soil elevation and zones within the soil profile in a mangrove forest

    USGS Publications Warehouse

    Whelan, K.R.T.; Smith, T. J., III; Anderson, G.H.; Ouellette, M.L.

    2009-01-01

    Soil elevation affects tidal inundation period, inundation frequency, and overall hydroperiod, all of which are important ecological factors affecting species recruitment, composition, and survival in wetlands. Hurricanes can dramatically affect a site's soil elevation. We assessed the impact of Hurricane Wilma (2005) on soil elevation at a mangrove forest location along the Shark River in Everglades National Park, Florida, USA. Using multiple depth surface elevation tables (SETs) and marker horizons we measured soil accretion, erosion, and soil elevation. We partitioned the effect of Hurricane Wilma's storm deposit into four constituent soil zones: surface (accretion) zone, shallow zone (0–0.35 m), middle zone (0.35–4 m), and deep zone (4–6 m). We report expansion and contraction of each soil zone. Hurricane Wilma deposited 37.0 (± 3.0 SE) mm of material; however, the absolute soil elevation change was + 42.8 mm due to expansion in the shallow soil zone. One year post-hurricane, the soil profile had lost 10.0 mm in soil elevation, with 8.5 mm of the loss due to erosion. The remaining soil elevation loss was due to compaction from shallow subsidence. We found prolific growth of new fine rootlets (209 ± 34 SE g m−2) in the storm deposited material suggesting that deposits may become more stable in the near future (i.e., erosion rate will decrease). Surficial erosion and belowground processes both played an important role in determining the overall soil elevation. Expansion and contraction in the shallow soil zone may be due to hydrology, and in the middle and bottom soil zones due to shallow subsidence. Findings thus far indicate that soil elevation has made substantial gains compared to site specific relative sea-level rise, but data trends suggest that belowground processes, which differ by soil zone, may come to dominate the long term ecological impact of storm deposit.

  19. A new bed elevation dataset for Greenland

    NASA Astrophysics Data System (ADS)

    Griggs, J. A.; Bamber, J. L.; Hurkmans, R. T. W. L.; Dowdesewell, J. A.; Gogineni, S. P.; Howat, I.; Mouginot, J.; Paden, J.; Palmer, S.; Rignot, E.; Steinhage, D.

    2012-11-01

    We present a new bed elevation dataset for Greenland derived from a combination of multiple airborne ice thickness surveys undertaken between the 1970s and 2011. Around 344 000 line kilometres of airborne data were used, with the majority of this having been collected since the year 2000, when the last comprehensive compilation was undertaken. The airborne data were combined with satellite-derived elevations for non glaciated terrain to produce a consistent bed digital elevation model (DEM) over the entire island including across the glaciated/ice free boundary. The DEM was extended to the continental margin with the aid of bathymetric data, primarily from a compilation for the Arctic. Ice shelf thickness was determined where a floating tongue exists, in particular in the north. The across-track spacing between flight lines warranted interpolation at 1 km postings near the ice sheet margin and 2.5 km in the interior. Grids of ice surface elevation, error estimates for the DEM, ice thickness and data sampling density were also produced alongside a mask of land/ocean/grounded ice/floating ice. Errors in bed elevation range from a minimum of 6 m to about 200 m, as a function of distance from an observation and local topographic variability. A comparison with the compilation published in 2001 highlights the improvement in resolution afforded by the new data sets, particularly along the ice sheet margin, where ice velocity is highest and changes most marked. We use the new bed and surface DEMs to calculate the hydraulic potential for subglacial flow and present the large scale pattern of water routing. We estimate that the volume of ice included in our land/ice mask would raise eustatic sea level by 7.36 m, excluding any solid earth effects that would take place during ice sheet decay.

  20. Nucleus accumbens response to gains in reputation for the self relative to gains for others predicts social media use

    PubMed Central

    Meshi, Dar; Morawetz, Carmen; Heekeren, Hauke R.

    2013-01-01

    Our reputation is important to us; we've experienced natural selection to care about our reputation. Recently, the neural processing of gains in reputation (positive social feedback concerning one's character) has been shown to occur in the human ventral striatum. It is still unclear, however, how individual differences in the processing of gains in reputation may lead to individual differences in real-world behavior. For example, in the real-world, one way that people currently maintain their reputation is by using social media websites, like Facebook. Furthermore, Facebook use consists of a social comparison component, where users observe others' behavior and can compare it to their own. Therefore, we hypothesized a relationship between the way the brain processes specifically self-relevant gains in reputation and one's degree of Facebook use. We recorded functional neuroimaging data while participants received gains in reputation, observed the gains in reputation of another person, or received monetary reward. We demonstrate that across participants, when responding to gains in reputation for the self, relative to observing gains for others, reward-related activity in the left nucleus accumbens predicts Facebook use. However, nucleus accumbens activity in response to monetary reward did not predict Facebook use. Finally, a control step-wise regression analysis showed that Facebook use primarily explains our results in the nucleus accumbens. Overall, our results demonstrate how individual sensitivity of the nucleus accumbens to the receipt of self-relevant social information leads to differences in real-world behavior. PMID:24009567

  1. Nucleus accumbens response to gains in reputation for the self relative to gains for others predicts social media use.

    PubMed

    Meshi, Dar; Morawetz, Carmen; Heekeren, Hauke R

    2013-01-01

    Our reputation is important to us; we've experienced natural selection to care about our reputation. Recently, the neural processing of gains in reputation (positive social feedback concerning one's character) has been shown to occur in the human ventral striatum. It is still unclear, however, how individual differences in the processing of gains in reputation may lead to individual differences in real-world behavior. For example, in the real-world, one way that people currently maintain their reputation is by using social media websites, like Facebook. Furthermore, Facebook use consists of a social comparison component, where users observe others' behavior and can compare it to their own. Therefore, we hypothesized a relationship between the way the brain processes specifically self-relevant gains in reputation and one's degree of Facebook use. We recorded functional neuroimaging data while participants received gains in reputation, observed the gains in reputation of another person, or received monetary reward. We demonstrate that across participants, when responding to gains in reputation for the self, relative to observing gains for others, reward-related activity in the left nucleus accumbens predicts Facebook use. However, nucleus accumbens activity in response to monetary reward did not predict Facebook use. Finally, a control step-wise regression analysis showed that Facebook use primarily explains our results in the nucleus accumbens. Overall, our results demonstrate how individual sensitivity of the nucleus accumbens to the receipt of self-relevant social information leads to differences in real-world behavior. PMID:24009567

  2. Reducing elevator energy use: A comparison of posted feedback and reduced elevator convenience.

    PubMed

    Houten, R V; Nau, P A; Merrigan, M

    1981-01-01

    The effects of two different procedures for reducing elevator energy use were assessed using a multiple-baseline design. In the first procedure, feedback about the amount of energy consumed by the elevators each week was posted on each elevator door. Later, signs advocating the use of stairs to save energy and improve health were posted next to the feedback signs. In the second procedure, the time required to travel between floors was increased by adding a delay to the elevator door closing mechanisms. Results indicated that neither feedback alone nor feedback plus educational signs reduced the amount of energy consumed by the elevators. However, use of the door delay reduced consumption by one-third in all elevators.A second experiment replicated the effect of the door delay on energy consumption and, in addition, demonstrated that the door delay also produced a reduction in the number of persons using the elevator. The second experiment also showed that, following an initial period during which a full delay was in effect, a gradual reduction of the delay interval resulted in continued energy conservation. Reduced convenience as a general strategy for energy conservation is discussed. PMID:16795648

  3. Predicting FCI gain with a nonverbal intelligence test

    NASA Astrophysics Data System (ADS)

    Semak, M. R.; Dietz, R. D.; Pearson, R. H.; Willis, C. W.

    2013-01-01

    We have administered both a commercial, nonverbal intelligence test (the GAMA) and Lawson's Classroom Test of Scientific Reasoning to students in two introductory physics classes to determine if either test can successfully predict normalized gains on the Force Concept Inventory. Since gain on the FCI is known to be related to gender, we adopted a linear model with gain on the FCI as the dependent variable and gender and a test score as the independent variables. We found that the GAMA score did not predict a significant amount of variation beyond gender. Lawson's test, however, did predict a small but significant variation beyond gender. When simple linear regressions were run separately for males and females with the Lawson score as a predictor, we found that the Lawson score did not significantly predict gains for females but was a marginally significant predictor for males.

  4. Ultrafast gain switching of THz quantum cascade lasers

    NASA Astrophysics Data System (ADS)

    Dhillon, S. S.; Jukam, N.; Oustinov, D.; Rungsawang, R.; Madéo, J.; Barbieri, S.; Manquest, C.; Sirtori, C.; Khanna, S. P.; Linfield, E. H.; Davies, A. G.; Tignon, J.

    2011-02-01

    Terahertz (THz) time domain spectroscopy (TDS) is widely used in a broad range of applications where knowledge of both the amplitude and phase of a THz wave can reveal useful information about a sample. However, a means of amplifying THz pulses which would be of great benefit for improving the applicability of TDS is lacking. While THz quantum cascade lasers (QCL) are promising devices for THz amplification, gain clamping limits the attainable amplification. Here we circumvent gain clamping and demonstrate amplification of THz pulses by ultrafast gain switching of a QCL via the use of an integrated Auston switch. This unclamps the gain by placing the laser in a non-equilibrium state that allows large amplification of the electromagnetic field within the cavity. This technique offers the potential to produce high field THz pulses that approach the QCL saturation field.

  5. What next for gain-of-function research in Europe?

    PubMed Central

    2015-01-01

    A working group on gain-of-function research set up by the European Academies Science Advisory Council (EASAC) has emphasised the importance of ensuring that the necessary safeguards and policies are in place PMID:26716473

  6. Gain-assisted control of the Goos-Haenchen shift

    SciTech Connect

    Ziauddin,; Qamar, Sajid

    2011-11-15

    A gain-assisted model is considered to study the Goos-Haenchen (GH) shift behavior in the reflected and transmitted light. In this model, a probe light is incident on a cavity containing three-level dilute gaseous atomic medium. The atom-field interaction follows two-photon Raman transitions, and the dielectric susceptibility of the medium exhibits dispersion and gain properties [L. J. Wang, A. Kuzmich, and A. Dogariu, Nature (London) 406, 227 (2000)]. Under appropriate conditions, two gain peaks are observed with anomalous dispersion between the peaks, whereas normal dispersion can be observed at and around the gain maxima. The manipulation of the detuning associated with the probe light field which interacts with the intracavity medium during its propagation through the cavity can lead to a control over negative and positive GH shift in the reflected and transmitted light beam via the anomalous and normal dispersion of the medium.

  7. Losing it: The Influence of Losses on Individuals' Normalized Gains

    NASA Astrophysics Data System (ADS)

    Miller, Kelly; Lasry, Nathaniel; Reshef, Orad; Dowd, Jason; Araujo, Ives; Mazur, Eric

    2010-10-01

    Researchers and practitioners routinely use the normalized gain (Hake, 1998) to evaluate the effectiveness of instruction. Normalized gain (g) has been useful in distinguishing active engagement from traditional instruction. Recently, concerns were raised about normalized gain because it implicitly neglects retention (or, equivalently, "losses"). That is to say, g assumes no right answers become wrong after instruction. We analyze individual standardized gain (G) and loss (L) in data collected at Harvard University during the first five years that Peer Instruction was developed. We find that losses are non-zero, and that losses are larger among students with lower pre-test performances. These preliminary results warrant further research, particularly with different student populations, to establish whether the failure to address loss changes the conclusions drawn from g.

  8. 1300-nm gain obtained with dysprosium-doped chloride crystals

    SciTech Connect

    Page, R.H.; Schaffers, K.I.; Beach, R.J.; Payne, S.A.; Krupke, W.F.

    1996-03-01

    Dy{sup 3+} - doped chloride crystals have high 1300-nm emission quantum yields. Pump - probe experiments on La Cl{sub 3}:Dy{sup 3+} demonstrate optical gain consistent with predictions based on spectroscopic cross sections and lifetimes.

  9. Strength gain and cementation of flexible pavement bases (revised)

    NASA Astrophysics Data System (ADS)

    Zimpfer, W. H.

    1991-02-01

    The strength gain of selected carbonate Florida Department of Transportation (FDOT) flexible pavement base materials is addressed. The gain in strength after aging of base sections constructed in an inside environment and outside environment was measured. Scanning electron microscope (SEM) photographs were also taken and examined to determine changes in structure. The materials investigated were: (1) bank run shell; (2) limerock; and (3) cemented coquina. Strength tests were the Clegg Impact Value (CIV) performed on inside and outside sections and a rigid plate test performed on the inside section. There was a small gain in strength for all three carbonate bases after 22 months. Changes in the matrix particles were observed in the SEM study. The three complementary phases (CIV, plate modulus, and SEM) tend to reinforce each other, indicating a small gain in strength.

  10. Effect of surfactants on weight gain in mice.

    PubMed

    Kaneene, J B; Ross, R W

    1986-03-01

    A study was conducted to determine if four surfactants can induce increased weight gain in the mouse. Basic-H, Triton X-100, Amway All Purpose Adjuvant and X-77 were put in water and fed to various groups of ICR 21 day old female mice for a period of 43 days. All the mice were clinically normal throughout the study period. Pathological examination of a random sample of the mice revealed no gross pathological changes. Similarly, histopathological examination of the lungs, livers and intestines did not reveal any visible lesions. Basic-H and Amway surfactants induced weight gain, though not significantly, better at 0.1% (V/V) concentration while X-77 and Triton X-100 induced weight gain better at 0.4% (V/V) concentration. Overall results show that none of the surfactants tested induced significant weight gain. PMID:3962176

  11. Online technology for teaching and learning-gains and losses.

    PubMed

    Cann, Alan

    2015-07-01

    This commentary describes recent developments in the use of online technologies, in particular social media and mobile devices, for teaching and learning and considers what has been gained and lost. PMID:26085489

  12. Review of health and productivity gains from better IEQ

    SciTech Connect

    Fisk, William J.

    2000-08-01

    The available scientific data suggest that existing technologies and procedures can improve indoor environmental quality (IEQ) in a manner that significantly increases productivity and health. While there is considerable uncertainty in the estimates of the magnitudes of productivity gains that may be obtained, the projected gains are very large. For the U.S., the estimated potential annual savings and productivity gains are $6 to $14 billion from reduced respiratory disease, $2 to $4 billion from reduced allergies and asthma, $10 to $30 billion from reduced sick building syndrome symptoms, and $20 to $160 billion from direct improvements in worker performance that are unrelated to health. Productivity gains that are quantified and demonstrated could serve as a strong stimulus for energy efficiency measures that simultaneously improve the indoor environment.

  13. What next for gain-of-function research in Europe?

    PubMed

    Fears, Robin; Ter Meulen, Volker

    2015-01-01

    A working group on gain-of-function research set up by the European Academies Science Advisory Council (EASAC) has emphasised the importance of ensuring that the necessary safeguards and policies are in place. PMID:26716473

  14. Context-specific adaptation of saccade gain in parabolic flight

    NASA Technical Reports Server (NTRS)

    Shelhamer, Mark; Clendaniel, Richard A.; Roberts, Dale C.

    2002-01-01

    Previous studies established that vestibular reflexes can have two adapted states (e.g., gains) simultaneously, and that a context cue (e.g., vertical eye position) can switch between the two states. Our earlier work demonstrated this phenomenon of context-specific adaptation for saccadic eye movements: we asked for gain decrease in one context state and gain increase in another context state, and then determined if a change in the context state would invoke switching between the adapted states. Horizontal and vertical eye position and head orientation could serve, to varying degrees, as cues for switching between two different saccade gains. In the present study, we asked whether gravity magnitude could serve as a context cue: saccade adaptation was performed during parabolic flight, which provides alternating levels of gravitoinertial force (0 g and 1.8 g). Results were less robust than those from ground experiments, but established that different saccade magnitudes could be associated with different gravity levels.

  15. 46 CFR 72.05-20 - Stairways, ladders, and elevators.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... elevators to a balcony within a space need not be enclosed, provided the stairway or elevator serves only... following requirements: (1) Where a continuous vertical deck penetration for a stairway or elevator exceeds... requirements of § 72.05-25(b)(9). (2) Where only two decks are served by a stairway or elevator, the...

  16. 46 CFR 72.05-20 - Stairways, ladders, and elevators.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... elevators to a balcony within a space need not be enclosed, provided the stairway or elevator serves only... following requirements: (1) Where a continuous vertical deck penetration for a stairway or elevator exceeds... requirements of § 72.05-25(b)(9). (2) Where only two decks are served by a stairway or elevator, the...

  17. 75. Southeast elevation of Forest Hills station looking Northwest ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    75. Southeast elevation of Forest Hills station - looking Northwest from junction of Washington and Walk Hill Streets. At left is the beginning of Section F-7 the exposed steel portion of elevated structure leading to the Forest Hills storage yard (demolished in 1985). - Boston Elevated Railway, Elevated Mainline, Washington Street, Boston, Suffolk County, MA

  18. 67. West elevation Green Street station looking East across ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    67. West elevation Green Street station - looking East across Washington Street along Green Street. In foreground is the reconstructed version of the intermediate level passenger platform which was originaly suspended from the elevated structure. - Boston Elevated Railway, Elevated Mainline, Washington Street, Boston, Suffolk County, MA

  19. West and south elevations, view to northeast. Proximity of house ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    West and south elevations, view to northeast. Proximity of house and trees precluded photography of north and east elevations, but building is symmetrical. Entry is in east elevation; windmill was mounted at third story level on north elevation. - Drew-Sherwood Farm, Tank House, 7927 Elk Grove Boulevard, Elk Grove, Sacramento County, CA

  20. 46 CFR 72.05-20 - Stairways, ladders, and elevators.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... following requirements: (1) Where a continuous vertical deck penetration for a stairway or elevator exceeds... requirements of 72.05-25(b)(9). (2) Where only two decks are served by a stairway or elevator, the integrity... elevators to a balcony within a space need not be enclosed, provided the stairway or elevator serves...