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Sample records for emso european multidisciplinary

  1. EMSO: European Multidisciplinary Seafloor Observatory

    NASA Astrophysics Data System (ADS)

    Favali, Paolo; Partnership, Emso

    2010-05-01

    EEMSO, an ESFRI Research Infrastructure, is the European-scale network of multidisciplinary seafloor observatories from the Arctic to the Black Sea with the scientific objective of long-term real-time monitoring of processes related to geosphere/biosphere/hydrosphere interactions. EMSO will enhance our understanding of processes through long time series appropriate to the scale of the phenomena, constituting the new frontier of studying Earth interior, deep-sea biology and chemistry and ocean processes. EMSO will reply also to the need expressed in the frame of GMES (Global Monitoring for Environment and Security) to develop a marine segment integrated in the in situ and satellite global monitoring system. The EMSO infrastructure will extend the coverage to the sea of the monitoring, integrating the land-based networks with multidisciplinary seafloor measurements. With this aim the two European research infrastructures EPOS (European Plate Observing System) and EMSO can operate in coordination in order to increase the mutual benefits. EMSO is presently at the stage of Preparatory Phase, funded in the EC FP7. The EMSO status, the perspectives and relations with other existing or incoming sensor networks and data infrastructures are outlined.

  2. EMSO: European multidisciplinary seafloor observatory

    NASA Astrophysics Data System (ADS)

    Favali, Paolo; Beranzoli, Laura

    2009-04-01

    EMSO has been identified by the ESFRI Report 2006 as one of the Research Infrastructures that European members and associated states are asked to develop in the next decades. It will be based on a European-scale network of multidisciplinary seafloor observatories from the Arctic to the Black Sea with the aim of long-term real-time monitoring of processes related to geosphere/biosphere/hydrosphere interactions. EMSO will enhance our understanding of processes, providing long time series data for the different phenomenon scales which constitute the new frontier for study of Earth interior, deep-sea biology and chemistry, and ocean processes. The development of an underwater network is based on past EU projects and is supported by several EU initiatives, such as the on-going ESONET-NoE, aimed at strengthening the ocean observatories' scientific and technological community. The EMSO development relies on the synergy between the scientific community and industry to improve European competitiveness with respect to countries such as USA, Canada and Japan. Within the FP7 Programme launched in 2006, a call for Preparatory Phase (PP) was issued in order to support the foundation of the legal and organisational entity in charge of building up and managing the infrastructure, and coordinating the financial effort among the countries. The EMSO-PP project, coordinated by the Italian INGV with participation by 11 institutions from as many European countries, started in April 2008 and will last four years.

  3. EMSO: European Multidisciplinary Seafloor Observatory

    NASA Astrophysics Data System (ADS)

    Favali, Paolo

    2010-05-01

    EMSO, a Research Infrastructure listed within ESFRI (European Strategy Forum on Research Infrastructures) Roadmap (Report 2006, http://cordis.europa.eu/esfri/roadmap.htm), is the European-scale network of multidisciplinary seafloor observatories from the Arctic to the Black Sea with the scientific objective of long-term real-time monitoring of processes related to geosphere/biosphere/hydrosphere interactions. EMSO will enhance our understanding of processes through long time series appropriate to the scale of the phenomena, constituting the new frontier of studying Earth interior, deep-sea biology and chemistry and ocean processes. The development of an underwater network is based on previous EU-funded projects since early '90 and is being supported by several EU initiatives, as the on-going ESONET-NoE, coordinated by IFREMER (2007-2011, http://www.esonet-emso.org/esonet-noe/), and aims at gathering together the Research Community of the Ocean Observatories. In 2006 the FP7 Capacities Programme launched a call for Preparatory Phase (PP) projects, that will provide the support to create the legal and organisational entities in charge of managing the infrastructures, and coordinating the financial effort among the countries. Under this call the EMSO-PP project was approved in 2007 with the coordination of INGV and the participation of other 11 Institutions of 11 countries. The project has started in April 2008 and will last 4 years. The EMSO is a key-infrastructure both for Ocean Sciences and for Solid Earth Sciences. In this respect it will enhance and complement profitably the capabilities of other European research infrastructures such as EPOS, ERICON-Aurora Borealis, and SIOS. The perspective of the synergy among EMSO and other ESFRI Research Infrastructures will be outlined. EMSO Partners: IFREMER-Institut Français de Recherche pour l'exploitation de la mer (France, ref. Roland Person); KDM-Konsortium Deutsche Meeresforschung e.V. (Germany, ref. Christoph

  4. EMSO: European Multidisciplinary Seafloor Observatory

    NASA Astrophysics Data System (ADS)

    Favali, P.; Partnership, Emso

    2009-04-01

    EMSO, a Research Infrastructure listed within ESFRI (European Strategy Forum on Research Infrastructures) Roadmap), is the European-scale network of multidisciplinary seafloor observatories from the Arctic to the Black Sea with the scientific objective of long-term real-time monitoring of processes related to geosphere/biosphere/hydrosphere interactions. EMSO will enhance our understanding of processes through long time series appropriate to the scale of the phenomena, constituting the new frontier of studying Earth interior, deep-sea biology and chemistry and ocean processes. EMSO will reply also to the need expressed in the frame of GMES (Global Monitoring for Environment and Security) to develop a marine segment integrated in the in situ and satellite global monitoring system. The EMSO development relays upon the synergy between the scientific community and the industry to improve the European competitiveness with respect to countries like USA/Canada, NEPTUNE, VENUS and MARS projects, Taiwan, MACHO project, and Japan, DONET project. In Europe the development of an underwater network is based on previous EU-funded projects since early '90, and presently supported by EU initiatives. The EMSO infrastructure will constitute the extension to the sea of the land-based networks. Examples of data recorded by seafloor observatories will be presented. EMSO is presently at the stage of Preparatory Phase (PP), funded in the EC FP7 Capacities Programme. The project has started in April 2008 and will last 4 years with the participation of 12 Institutions representing 12 countries. EMSO potential will be significantly increased also with the interaction with other Research Infrastructures addressed to Earth Science. 2. IFREMER-Institut Français de Recherche pour l'exploitation de la mer (France, ref. Roland Person); KDM-Konsortium Deutsche Meeresforschung e.V. (Germany, ref. Christoph Waldmann); IMI-Irish Marine Institute (Ireland, ref. Michael Gillooly); UTM-CSIC-Unidad de

  5. The European Multidisciplinary Seafloor and Water-column Observatory Consortium (EMSO-ERIC): Impact, Progress, and Plans.

    NASA Astrophysics Data System (ADS)

    Best, Mairi

    2016-04-01

    EMSO is forging ahead through the next challenge in Earth-Ocean Science: How to co-ordinate ocean data acquisition, analysis and response across provincial, national, regional, and global scales. EMSO provides power, communications, sensors, and data infrastructure for continuous, high resolution, (near)-real-time, interactive ocean observations across a truly multi- and interdisciplinary range of research areas including biology, geology, chemistry, physics, engineering, and computer science; from polar to tropical environments, through the water column down to the abyss. 11 deep sea and 4 shallow nodes span from Arctic through the Atlantic and Mediterranean, to the Black Sea. The EMSO Preparatory Phase (FP7) project led to the Interim phase (involving 13 countries) of forming the legal entity: the EMSO European Research Infrastructure Consortium (EMSO-ERIC). The open user community is through ESONET-Vi (European Seafloor Observatory NETwork - The Vision), following on the extensive scientific community planning contributions of the ESONET-NoE (FP6) project. The further progress made through the FixO3 project (FP7) will also benefit the development of this shared infrastructure. Coordination among nodes is being strengthened through the EMSOdev project (H2020) which will produce the EMSO Generic Instrument Module (EGIM) - standardised observations of temperature, pressure, salinity, dissolved oxygen, turbidity, chlorophyll fluorescence, currents, passive acoustics, pH, pCO2, and nutrients. Early installations are now being upgraded; for example in October 2015 EMSO-France deployed a second cable and junction box serving the Ligurian Sea Node in order to monitor slope stability offshore Nice; in 2016 the EMSO Azores Node will receive a major upgrade that will double its observing capacity; for the Ionian Sea Node the Capo Passero site will be installed and the Catania site will be upgraded. Significant findings are already coming in; for example high frequency

  6. Integrating sea floor observatory data: the EMSO data infrastructure

    NASA Astrophysics Data System (ADS)

    Huber, Robert; Azzarone, Adriano; Carval, Thierry; Doumaz, Fawzi; Giovanetti, Gabriele; Marinaro, Giuditta; Rolin, Jean-Francois; Beranzoli, Laura; Waldmann, Christoph

    2013-04-01

    The European research infrastructure EMSO is a European network of fixed-point, deep-seafloor and water column observatories deployed in key sites of the European Continental margin and Arctic. It aims to provide the technological and scientific framework for the investigation of the environmental processes related to the interaction between the geosphere, biosphere, and hydrosphere and for a sustainable management by long-term monitoring also with real-time data transmission. Since 2006, EMSO is on the ESFRI (European Strategy Forum on Research Infrastructures) roadmap and has entered its construction phase in 2012. Within this framework, EMSO is contributing to large infrastructure integration projects such as ENVRI and COOPEUS. The EMSO infrastructure is geographically distributed in key sites of European waters, spanning from the Arctic, through the Atlantic and Mediterranean Sea to the Black Sea. It is presently consisting of thirteen sites which have been identified by the scientific community according to their importance respect to Marine Ecosystems, Climate Changes and Marine GeoHazards. The data infrastructure for EMSO is being designed as a distributed system. Presently, EMSO data collected during experiments at each EMSO site are locally stored and organized in catalogues or relational databases run by the responsible regional EMSO nodes. Three major institutions and their data centers are currently offering access to EMSO data: PANGAEA, INGV and IFREMER. In continuation of the IT activities which have been performed during EMSOs twin project ESONET, EMSO is now implementing the ESONET data architecture within an operational EMSO data infrastructure. EMSO aims to be compliant with relevant marine initiatives such as MyOceans, EUROSITES, EuroARGO, SEADATANET and EMODNET as well as to meet the requirements of international and interdisciplinary projects such as COOPEUS and ENVRI, EUDAT and iCORDI. A major focus is therefore set on standardization and

  7. Latest highlights from the EMSO-Açores deep sea observatory

    NASA Astrophysics Data System (ADS)

    Sarradin, Pierre-Marie; Blandin, Jerome; Cannat, Mathilde; Sarrazin, Jozée; Godfroy, Anne; Rommevaux, Celine; Colaço, Ana; Crawford, Wayne; Ballu, Valerie; Escartin, Javier; Chavagnac, Valerie; Reverdin, Gilles

    2016-04-01

    Pierre Marie Sarradin, Jérome Blandin, Mathilde Cannat, Jozée Sarrazin, Anne Godfroy, Céline Rommevaux, Ana Colaço, Valérie Ballu, Wayne Crawford, Javier Escartin, Valérie Chavagnac, Gilles Reverdin and the MoMARSAT team The MoMAR "Monitoring the Mid-Atlantic Ridge" project was initiated by InterRidge in 1998 to study the environmental instability resulting from active mid-ocean-ridge processes at hydrothermal vent fields south of the Azores. It is now a component of the EMSO (European Multidisciplinary Subsea Observatory) European programs, which coordinate eulerian observatory initiatives in European seas. The EMSO-Açores observatory focuses on two main questions: What are the feedbacks between volcanism, deformation, seismicity, and hydrothermalism at a slow spreading mid-ocean ridge and how does the hydrothermal ecosystem couple with these sub-seabed processes? The uncabled observing system was deployed in 2010 in the Lucky Strike vent field at 1700 m depth. It comprises two Sea Monitoring Nodes (SeaMoN), a first dedicated to geophysics -seismicity and geodesy- and a second dedicated to ecological studies. The nodes are acoustically linked to a surface relay buoy, ensuring satellite communication to a land base station in Brest (France). An array of autonomous sensors (OBSs, pressure probes, temperature probes in selected smokers, current meters and temperature probes in the water column) and colonization devices complete the infrastructure. A site studies program contributes to increase the set of accessible parameters and to extend the spatial coverage of the study. This paper will present the latest highlights of EMSO-Açores studies, underlining the complementarity of spatial and temporal studies.

  8. The relevance of large scale environmental research infrastructures from the point of view of Ethics: the case of EMSO

    NASA Astrophysics Data System (ADS)

    Favali, Paolo; Beranzoli, Laura; Best, Mairi; Franceschini, PierLuigi; Materia, Paola; Peppoloni, Silvia; Picard, John

    2014-05-01

    EMSO (European Multidisciplinary Seafloor and Water Column Observatory) is a large-scale European Research Infrastructure (RI). It is a geographically distributed infrastructure composed of several deep-seafloor and water-column observatories, which will be deployed at key sites in European waters, spanning from the Arctic, through the Atlantic and Mediterranean, to the Black Sea, with the basic scientific objective of real-time, long-term monitoring of environmental processes related to the interaction between the geosphere, biosphere and hydrosphere. EMSO is one of the environmental RIs on the ESFRI roadmap. The ESRFI Roadmap identifies new RIs of pan-European importance that correspond to the long term needs of European research communities. EMSO will be the sub-sea segment of the EU's large-scale Earth Observation program, Copernicus (previously known as GMES - Global Monitoring for Environment and Security) and will significantly enhance the observational capabilities of European member states. An open data policy compliant with the recommendations being developed within the GEOSS initiative (Global Earth Observation System of Systems) will allow for shared use of the infrastructure and the exchange of scientific information and knowledge. The processes that occur in the oceans have a direct impact on human societies, therefore it is crucial to improve our understanding of how they operate and interact. To encompass the breadth of these major processes, sustained and integrated observations are required that appreciate the interconnectedness of atmospheric, surface ocean, biological pump, deep-sea, and solid-Earth dynamics and that can address: • natural and anthropogenic change; • interactions between ecosystem services, biodiversity, biogeochemistry, physics, and climate; • impacts of exploration and extraction of energy, minerals, and living resources; • geo-hazard early warning capability for earthquakes, tsunamis, gas-hydrate release, and slope

  9. MELODI: the 'Multidisciplinary European Low-Dose Initiative'.

    PubMed

    Belli, M; Salomaa, S; Ottolenghi, A

    2011-02-01

    The importance of research to reduce uncertainties in risk assessment of low and protracted exposures is now recognised globally. In Europe a new initiative, called 'Multidisciplinary European LOw Dose Initiative' (MELODI), has been proposed by a 'European High Level and Expert Group on low-dose risk research' (www.hleg.de), aimed at integrating national and EC (Euratom) efforts. Five national organisations: BfS (DE), CEA (FR), IRSN (FR), ISS (IT) and STUK (FI), with the support of the EC, have initiated the creation of MELODI by signing a letter of intent. In the forthcoming years, MELODI will integrate in a step-by-step approach EU institutions with significant programmes in the field and will be open to other scientific organisations and stakeholders. A key role of MELODI is to develop and maintain over time a strategic research agenda (SRA) and a road map of scientific priorities within a multidisciplinary approach, and to transfer the results for the radiation protection system. Under the coordination of STUK a network has been proposed in the 2009 Euratom Programme, called DoReMi (Low-Dose Research towards Mutidisciplinary Integration), which can help the integration process within the MELODI platform. DoReMi and the First MELODI Open Workshop, organised by BfS in September 2009, are now important inputs for the European SRA. PMID:21106638

  10. The importance of a multidisciplinary approach for solid earth geophysics in Seafloor Observatories data analysis

    NASA Astrophysics Data System (ADS)

    Embriaco, Davide; De Caro, Mariagrazia; De Santis, Angelo; Etiope, Giuseppe; Frugoni, Francesco; Giovanetti, Gabriele; Lo Bue, Nadia; Marinaro, Giuditta; Monna, Stephen; Montuori, Caterina; Sgroi, Tiziana; Beranzoli, Laura; Favali, Paolo

    2016-04-01

    Continuous time-series in deep ocean waters are the basis for an original approach in ocean exploration. The observation of phenomena variability over time is key to understanding many Earth processes, among which: hydrothermal systems, active tectonics, and ecosystem life cycles. Geo-hazards at sea have often been studied with a single-parameter approach on a short time-scale, but it is now becoming clear that to understand these phenomena and, specifically, to identify precursors to very energetic events, such as mega-earthquakes, tsunamis and volcanic eruptions, continuous long-term multiparameter monitoring is strongly needed. In fact, given a signal of interest, by using several sensors recording simultaneously it is possible to identify the contribution of different sources to this signal, and to be less prone to false associations. In Europe, large cabled systems with marine sensors are being developed for near real-time and real-time long-term monitoring of ocean processes within the EMSO (European Multidisciplinary Seafloor and water column Observatory www.emso-eu.org) Research Infrastructure. Obtaining good quality long-term multiparameter data from sensors on-board seafloor observatories, which are the base of a multidisciplinary approach, is a challenging task. We describe the main steps we have taken to retrieve good quality multiparametric data acquired by GEOSTAR class seafloor observatories, both standalone and cabled, deployed at various sites offshore European coast during the last decade. Starting from this data we show the application of a multidisciplinary approach with some examples coming from experiments in EMSO sites.

  11. TRANSAUTOPHAGY: European network for multidisciplinary research and translation of autophagy knowledge.

    PubMed

    Casas, Caty; Codogno, Patrice; Pinti, Marcello; Batoko, Henri; Morán, María; Proikas-Cezanne, Tassula; Reggiori, Fulvio; Sirko, Agnieszka; Soengas, María S; Velasco, Guillermo; Lafont, Frank; Lane, Jon; Faure, Mathias; Cossarizza, Andrea

    2016-03-01

    A collaborative consortium, named "TRANSAUTOPHAGY," has been created among European research groups, comprising more than 150 scientists from 21 countries studying diverse branches of basic and translational autophagy. The consortium was approved in the framework of the Horizon 2020 Program in November 2015 as a COST Action of the European Union (COST means: CO-operation in Science and Technology), and will be sponsored for 4 years. TRANSAUTOPHAGY will form an interdisciplinary platform for basic and translational researchers, enterprises and stakeholders of diverse disciplines (including nanotechnology, bioinformatics, physics, chemistry, biology and various medical disciplines). TRANSAUTOPHAGY will establish 5 different thematic working groups, formulated to cooperate in research projects, share ideas, and results through workshops, meetings and short term exchanges of personnel (among other initiatives). TRANSAUTOPHAGY aims to generate breakthrough multidisciplinary knowledge about autophagy regulation, and to boost translation of this knowledge into biomedical and biotechnological applications. PMID:27046256

  12. 2013 Mt. Etna Pyroclastic Activity through the ADCP Recordings of NEMO-SN1 Multidisciplinary Seafloor Observatory

    NASA Astrophysics Data System (ADS)

    Lo Bue, N.; Sgroi, T.; Giovinetti, G.; Marinaro, G.; Favali, P.

    2014-12-01

    The Acoustic Doppler Current Profiler (ADCP) is one of the most useful sensor used to measure speed and direction of sea currents in the water column. More often ADCPs are being also used to monitor concentration of suspended matter in rivers or in marine environments by the analysis of the acoustic backscatter intensity. In the framework of the European Research Infrastructure EMSO (European Multidisciplinary Seafloor and water-column Observatory, www.emso-eu.org), its cabled node, the NEMO-SN1 multidisciplinary seafloor observatory, was deployed in the Western Ionian Sea (Southern Italy) at a depth of 2100 m, about 25 km off-shore Eastern Sicily close to the submarine slope of the Mt. Etna volcano. Starting from February 2013, the Mt. Etna was interested by thirteen different parossistic events producing intense eruption followed by pyroclastic fallout that reached distances of tens kilometres from the eruptive centre. Four of these events affected the ESE sector with a consequent fallout in the Western Ionian Sea and they were detected by NEMO-SN1. In fact, its scientific payload also included an ADCP (RDI WorkHorse 600 kHz) with the main aim to monitor the hydrodynamic conditions of about 30 metres of the water column above the station. Surprisingly, this sensor offered spectacular recordings of the Mt. Etna pyroclastic activity occurred on 2013 wich affected the ESE sector. This work aims to present new records of pyroclastic fallout associated to explosive events observed at sea bottom by the analysis of backscatter signal of the ADCP. A multidisciplinary approach taking into account the Mt. Etna eruptive activity as well as the local oceanographic dynamic is necessary to describe marine processes involved in volcanic ash sedimentation.

  13. European Marine Infrastructures: perspectives for Marine and Earth Sciences

    NASA Astrophysics Data System (ADS)

    Favali, P.; Beranzoli, L.; Egerton, P.; Le Traon, P. Y.; Los, W.

    2009-04-01

    The European Commission (EC) is supporting a variety of Research Infrastructures in many different scientific fields: Social Sciences and Humanities, Environmental Sciences, Energy, Biological and Medical Sciences, Physical Sciences and Engineering and e-Infrastructures. All these infrastructures are included in the new report of the "European Roadmap for Research Infrastructures" published in late 2008 by ESFRI (European Strategy Forum on Research Infrastructures, http://cordis.europa.eu/esfri/). In particular, some research infrastructures for the Environmental Sciences specifically addressed to the marine environment are presented: • EMSO (European Multidisciplinary Seafloor Observatory). The development of this underwater network is being supported by several other EC initiatives, ESONET-NoE (European Seas Network), coordinated by IFREMER (http://www.esonet-emso.org/esonet-noe/). • ERICON AURORA BOREALIS (European Research Icebreaker Consortium, http://www.eri-aurora-borealis.eu/). • EURO-ARGO (Global Ocean Observing Infrastructure, http://www.euro-argo.eu/). • LIFEWATCH (E-science and technology infrastructure for biodiversity data and observatories, http://www.lifewatch.eu/). In particular through its scientific marine networks: EUR-OCEANS (European Network of Excellence for Ocean Ecosystems Analysis, http://www.eur-oceans.eu/); MARBEF-NoE (MARine Biodiversity and Ecosystem Functioning, http://www.marbef.org/ and Marine Genomics (http://www.marine-genomics-europe.org/). Possible profitable links with new research infrastructures recently included in the roadmap, such as EPOS (European Plate Observing System) and SIAEOS (Svalbard Integrated Arctic Earth Observing System) are also pointed out. The marine EC infrastructures presented constitute the fundamental tools to support the Earth Sciences, both terrestrial and marine.

  14. Mucopolysaccharidosis type II: European recommendations for the diagnosis and multidisciplinary management of a rare disease

    PubMed Central

    2011-01-01

    Mucopolysaccharidosis type II (MPS II) is a rare, life-limiting, X-linked recessive disease characterised by deficiency of the lysosomal enzyme iduronate-2-sulfatase. Consequent accumulation of glycosaminoglycans leads to pathological changes in multiple body systems. Age at onset, signs and symptoms, and disease progression are heterogeneous, and patients may present with many different manifestations to a wide range of specialists. Expertise in diagnosing and managing MPS II varies widely between countries, and substantial delays between disease onset and diagnosis can occur. In recent years, disease-specific treatments such as enzyme replacement therapy and stem cell transplantation have helped to address the underlying enzyme deficiency in patients with MPS II. However, the multisystem nature of this disorder and the irreversibility of some manifestations mean that most patients require substantial medical support from many different specialists, even if they are receiving treatment. This article presents an overview of how to recognise, diagnose, and care for patients with MPS II. Particular focus is given to the multidisciplinary nature of patient management, which requires input from paediatricians, specialist nurses, otorhinolaryngologists, orthopaedic surgeons, ophthalmologists, cardiologists, pneumologists, anaesthesiologists, neurologists, physiotherapists, occupational therapists, speech therapists, psychologists, social workers, homecare companies and patient societies. Take-home message Expertise in recognising and treating patients with MPS II varies widely between countries. This article presents pan-European recommendations for the diagnosis and management of this life-limiting disease. PMID:22059643

  15. Report on the 2013 European Multidisciplinary Cancer Congress—ECC 17, Amsterdam, 27 September–1 October 2013: nursing highlights

    PubMed Central

    Caruso, Rosario; Pasquale, Cristina Di; Lichosik, Danuta; Dellafirore, Federica; Pittella, Francesco

    2013-01-01

    The European Cancer Organisation (ECCO) was founded on the ideas of the former Federation of European Cancer Societies (FECS). The ECCO was officially announced at the European Cancer Conference in Barcelona in September 2007, replacing the FECS as a dynamic new entity. Through its members, the ECCO represents the interests of over 50,000 professionals in oncology. The ECCO continues to expand its outreach and education through its prestigious biennial series of Congresses. This report highlights the nursing contributions at the seventeenth ECCO Congress in Amsterdam. At the congress, there were more than 17,000 professionals involved in the struggle against cancer. A record number of abstracts (3306) were submitted, almost 40% more than the 2011 conference. Related topics during nursing sessions were often aimed at investigating the meaning of the multidisciplinary approach and what it implies for daily practice under different profiles. The debates showed that the multidisciplinary approach primarily means ‘new challenges’ for all the practitioners involved. The main challenge for nurses is to meet the needs of a rapidly changing society with some European peculiarities, such as the ageing population, the escalating costs of healthcare in a period of economic crises, fast changing treatments, changes in cancer services and the way nurses deliver care, and multidisciplinary empowerment as a modern concept of care. In this landscape, we also have to consider that cancer often becomes a chronic disease with an increasing number of treatment lines, an increasing number of survivors, and more conscious and exigent patients. We also have to consider the importance of diversity in cancer care. PMID:24171051

  16. Multidisciplinary strategies to improve treatment outcomes in hepatocellular carcinoma: a European perspective.

    PubMed

    Colombo, Massimo; Raoul, Jean-Luc; Lencioni, Riccardo; Galle, Peter R; Zucman-Rossi, Jessica; Bañares, Rafael; Seehofer, Daniel; Neuhaus, Peter; Johnson, Philip

    2013-06-01

    Hepatocellular carcinoma (HCC) is a complex disease with a poor prognosis. Incidence and mortality rates are increasing in many geographical regions, indicating a need for better management strategies. Among several risk factors for HCC, the most common are cirrhosis because of chronic hepatitis B virus or hepatitis C virus infection and alcohol consumption, obesity, and diabetes. In some patients, combined risk factors present additional challenges to the prevention and treatment of HCC. Screening and surveillance of high-risk populations varies widely by geographic regions, and access to optimal surveillance is critical for early diagnosis. The treatment choice for HCC depends on the cancer stage, patient performance status, and liver function and requires a multidisciplinary approach and close cooperation among specialists for the best patient outcomes. Despite advances in surgical treatments and locoregional therapies, recurrence and liver failure remain significant challenges. The pathogenesis of HCC is a multistep and complex process, wherein angiogenesis plays an important role. The multikinase inhibitor sorafenib is the only approved targeted agent for advanced HCC, although promising results have been obtained with other targeted agents and combinations, and the results of ongoing trials are eagerly awaited. Clinical trials with rigorous study designs, including molecular classification and validation of new molecular biomarkers, are required to improve the personalized treatment of HCC. This article provides an overview of HCC and was developed through a review of relevant literature, clinical trial data, and updated clinical guidelines. PMID:23628963

  17. The European Fixed point Open Ocean Observatory network (FixO3): Multidisciplinary observations from the air-sea interface to the deep seafloor

    NASA Astrophysics Data System (ADS)

    Lampitt, Richard; Cristini, Luisa; Alexiou, Sofia

    2015-04-01

    The Fixed point Open Ocean Observatory network (FixO3, http://www.fixo3.eu/ ) integrates 23 European open ocean fixed point observatories and improves access to these infrastructures for the broader community. These provide multidisciplinary observations in all parts of the oceans from the air-sea interface to the deep seafloor. Started in September 2013 with a budget of 7 Million Euros over 4 years, the project has 29 partners drawn from academia, research institutions and SME's coordinated by the National Oceanography Centre, UK. Here we present the programme's achievements in the 18 months and the activities of the 12 Work Packages which have the objectives to: • integrate and harmonise the current procedures and processes • offer free access to observatory infrastructures to those who do not have such access, and free and open data services and products • innovate and enhance the current capability for multidisciplinary in situ ocean observation Open ocean observation is a high priority for European marine and maritime activities. FixO3 provides important data and services to address the Marine Strategy Framework Directive and in support of the European Integrated Maritime Policy. FixO3 provides a strong integrated framework of open ocean facilities in the Atlantic from the Arctic to the Antarctic and throughout the Mediterranean, enabling an integrated, regional and multidisciplinary approach to understand natural and anthropogenic change in the ocean.

  18. The role of the Arrhythmia Team, an integrated, multidisciplinary approach to treatment of patients with cardiac arrhythmias: results of the European Heart Rhythm Association survey.

    PubMed

    Fumagalli, Stefano; Chen, Jian; Dobreanu, Dan; Madrid, Antonio Hernandez; Tilz, Roland; Dagres, Nikolaos

    2016-04-01

    Management of patients with cardiac arrhythmias is increasingly complex because of continuous technological advance and multifaceted clinical conditions associated with ageing of the population, the presence of co-morbidities and the need for polypharmacy. The aim of this European Heart Rhythm Association Scientific Initiatives Committee survey was to provide an insight into the role of the Arrhythmia Team, an integrated, multidisciplinary approach to management of patients with cardiac arrhythmias. Forty-eight centres from 18 European countries replied to the Web-based questionnaire. The presence of an Arrhythmia Team was reported by 44% of the respondents, whereas 17% were not familiar with this term. Apart from the electrophysiologist, health professionals who should belong to such teams, according to the majority of the respondents, include a clinical cardiologist, a nurse, a cardiac surgeon, a heart failure specialist, a geneticist, and a geriatrician. Its main activity should be dedicated to the management of patients with complex clinical conditions or refractory or inherited forms of arrhythmias. When present, the Arrhythmia Team was considered helpful by 95% of respondents; the majority of centres (79%) agreed that it should be implemented. The Arrhythmia Team seems to be connected to important expectations in the management of cardiac arrhythmias. The efficacy of such an integrated and multidisciplinary approach should be encouraged and tested in clinical practice. PMID:27174994

  19. Monitoring fin whale (Balaenoptera physalus) acoustic presence by means of a low frequency seismic hydrophone in Western Ionian Sea, EMSO site.

    NASA Astrophysics Data System (ADS)

    Sciacca, Virginia; Caruso, Francesco; Chierici, Francesco; De Domenico, Emilio; Embriaco, Davide; Favali, Paolo; Giovanetti, Gabriele; Larosa, Giuseppina; Pavan, Gianni; Pellegrino, Carmelo; Pulvirenti, Sara; Riccobene, Giorgio; Simeone, Francesco; Viola, Salvatore; Beranzoli, Laura; Marinaro, Giuditta

    2015-04-01

    In 2012, the NEMO-SN1 multidisciplinary seafloor platform was deployed in the Gulf of Catania at a depth of 2100 m. By using the low bandwidth seismic hydrophone SMID DT405D (1Hz multidisciplinary projects connected to "KM3NeT" and "EMSO" will give us the chance to better understand the animals' occurrence in the area and to investigate their acoustic behavior and population dynamics.

  20. Multidisciplinary Care.

    PubMed

    Daly, Megan E; Riess, Jonathan W

    2016-01-01

    Optimal multidisciplinary care of the lung cancer patient at all stages should encompass integration of the key relevant medical specialties, including not only medical, surgical, and radiation oncology, but also pulmonology, interventional and diagnostic radiology, pathology, palliative care, and supportive services such as physical therapy, case management, smoking cessation, and nutrition. Multidisciplinary management starts at staging and tissue diagnosis with pathologic and molecular phenotyping, extends through selection of a treatment modality or modalities, management of treatment and cancer-related symptoms, and to survivorship and end-of-life care. Well-integrated multidisciplinary care may reduce treatment delays, improve cancer-specific outcomes, and enhance quality of life. We address key topics and areas of ongoing investigation in multidisciplinary decision making at each stage of the lung cancer treatment course for early-stage, locally advanced, and metastatic lung cancer patients. PMID:27535399

  1. MoMar-Demo at Lucky Strike. A near-real time multidisciplinary observatory of hydrothermal processes and ecosystems at the Mid-Atlantic Ridge

    NASA Astrophysics Data System (ADS)

    Cannat, M.; Sarradin, P.; Blandin, J.; Escartin, J.; Colaco, A.; MoMAR-Demo Scientific Party : Aron Michael, Aumont Virginie, Baillard Christian, Ballu Valérie, Barreyre Thibaut, Blandin Jérôme, Blin Alexandre, Boulart Cédric, Cannat Mathilde, Carval Thierry, Castillo Alain, Chavagnac Valérie, Coail Jean Yves, Colaço Ana, Corela Carlos, Courrier Christophe, Crawford Wayne, Cuvelier Daphné, Daniel Romuald, Dausse Denis, Escartin Javier, Fabrice Fontaine, Gabsi Taoufik, Gayet Nicolas, Guyader Gérard, Lallier François, Lecomte Benoit, Legrand Julien, Lino Silva, Miranda Miguel, Mitard Emmelyne, Pichavant Pascal, Pot Olivier, Reverdin Gilles, Rommevaux Céline, Sarradin Pierre Marie, Sarrazin Jozée, Tanguy Virginie, Villinger Heinrich, Zbinden Magali

    2011-12-01

    The MoMAR "Monitoring the Mid-Atlantic Ridge" project was initiated by InterRidge in 1998 to study the environmental instability resulting from active mid-ocean-ridge processes at hydrothermal vent fields south of the Azores. It then developped into a component of the ESONET (European Seafloor Observatory Network) and EMSO (European Multidisciplinary Subsea Observatory) programs, which coordinate eulerian observatory initiatives in the seas around Europe. MoMAR experiments have started in 2006 and address two main questions : What are the feedbacks between volcanism, deformation, seismicity, and hydrothermalism at a slow spreading mid-ocean ridge? and How does the hydrothermal ecosystem couple with these sub-seabed processes? The MoMAR-Demo project started in 2010 with partial support from ESONET. It has been implemented so far by 2 cruises of the RV Pourquoi Pas ? during which we successfully deployed (in 2010), and upgraded (in 2011) a near-realtime buoyed observatory system. The system comprises two Sea Monitoring Nodes (SeaMoN) at the seafloor, which are acoustically linked to a surface relay buoy (BoRel), ensuring satellite communication to a land base station in Brest (France). One SeaMoN node connects to a 3-components seismometer and an hydrophone for seismic event detection, and two pressure probes for geodetic measurements, and the other SeaMoN node connects to a video camera, a dissolved-iron analyzer, and an optode (oxygen and temperature probe) for ecological time studies. The BOREL transmission buoy is equiped with GPS (geodetic experiment and buoy location) and meteo station. Data and/or status signals from these sensors are transmitted every 6 hours, and put on line in compliance with the ESONET-EMSO data policy (temporary access through http://www.ifremer.fr/WC2en/allEulerianNetworks). The MoMAR-Demo system also allows for interactive connections and changes of data transmission rates on demand. It is nested in arrays of autonomous sensors (OBSs

  2. The International Multidisciplinary Consensus Conference on Multimodality Monitoring in Neurocritical Care: a list of recommendations and additional conclusions: a statement for healthcare professionals from the Neurocritical Care Society and the European Society of Intensive Care Medicine.

    PubMed

    Le Roux, Peter; Menon, David K; Citerio, Giuseppe; Vespa, Paul; Bader, Mary Kay; Brophy, Gretchen; Diringer, Michael N; Stocchetti, Nino; Videtta, Walter; Armonda, Rocco; Badjatia, Neeraj; Bösel, Julian; Chesnut, Randall; Chou, Sherry; Claassen, Jan; Czosnyka, Marek; De Georgia, Michael; Figaji, Anthony; Fugate, Jennifer; Helbok, Raimund; Horowitz, David; Hutchinson, Peter; Kumar, Monisha; McNett, Molly; Miller, Chad; Naidech, Andrew; Oddo, Mauro; Olson, DaiWai; O'Phelan, Kristine; Provencio, J Javier; Puppo, Corinna; Riker, Richard; Roberson, Claudia; Schmidt, Michael; Taccone, Fabio

    2014-12-01

    Careful patient monitoring using a variety of techniques including clinical and laboratory evaluation, bedside physiological monitoring with continuous or non-continuous techniques and imaging is fundamental to the care of patients who require neurocritical care. How best to perform and use bedside monitoring is still being elucidated. To create a basic platform for care and a foundation for further research the Neurocritical Care Society in collaboration with the European Society of Intensive Care Medicine, the Society for Critical Care Medicine and the Latin America Brain Injury Consortium organized an international, multidisciplinary consensus conference to develop recommendations about physiologic bedside monitoring. This supplement contains a Consensus Summary Statement with recommendations and individual topic reviews as a background to the recommendations. In this article, we highlight the recommendations and provide additional conclusions as an aid to the reader and to facilitate bedside care. PMID:25501689

  3. Consensus summary statement of the International Multidisciplinary Consensus Conference on Multimodality Monitoring in Neurocritical Care: a statement for healthcare professionals from the Neurocritical Care Society and the European Society of Intensive Care Medicine.

    PubMed

    Le Roux, Peter; Menon, David K; Citerio, Giuseppe; Vespa, Paul; Bader, Mary Kay; Brophy, Gretchen M; Diringer, Michael N; Stocchetti, Nino; Videtta, Walter; Armonda, Rocco; Badjatia, Neeraj; Böesel, Julian; Chesnut, Randall; Chou, Sherry; Claassen, Jan; Czosnyka, Marek; De Georgia, Michael; Figaji, Anthony; Fugate, Jennifer; Helbok, Raimund; Horowitz, David; Hutchinson, Peter; Kumar, Monisha; McNett, Molly; Miller, Chad; Naidech, Andrew; Oddo, Mauro; Olson, DaiWai; O'Phelan, Kristine; Provencio, J Javier; Puppo, Corinna; Riker, Richard; Robertson, Claudia; Schmidt, Michael; Taccone, Fabio

    2014-12-01

    Neurocritical care depends, in part, on careful patient monitoring but as yet there are little data on what processes are the most important to monitor, how these should be monitored, and whether monitoring these processes is cost-effective and impacts outcome. At the same time, bioinformatics is a rapidly emerging field in critical care but as yet there is little agreement or standardization on what information is important and how it should be displayed and analyzed. The Neurocritical Care Society in collaboration with the European Society of Intensive Care Medicine, the Society for Critical Care Medicine, and the Latin America Brain Injury Consortium organized an international, multidisciplinary consensus conference to begin to address these needs. International experts from neurosurgery, neurocritical care, neurology, critical care, neuroanesthesiology, nursing, pharmacy, and informatics were recruited on the basis of their research, publication record, and expertise. They undertook a systematic literature review to develop recommendations about specific topics on physiologic processes important to the care of patients with disorders that require neurocritical care. This review does not make recommendations about treatment, imaging, and intraoperative monitoring. A multidisciplinary jury, selected for their expertise in clinical investigation and development of practice guidelines, guided this process. The GRADE system was used to develop recommendations based on literature review, discussion, integrating the literature with the participants' collective experience, and critical review by an impartial jury. Emphasis was placed on the principle that recommendations should be based on both data quality and on trade-offs and translation into clinical practice. Strong consideration was given to providing pragmatic guidance and recommendations for bedside neuromonitoring, even in the absence of high quality data. PMID:25208678

  4. Consensus summary statement of the International Multidisciplinary Consensus Conference on Multimodality Monitoring in Neurocritical Care : a statement for healthcare professionals from the Neurocritical Care Society and the European Society of Intensive Care Medicine.

    PubMed

    Le Roux, Peter; Menon, David K; Citerio, Giuseppe; Vespa, Paul; Bader, Mary Kay; Brophy, Gretchen M; Diringer, Michael N; Stocchetti, Nino; Videtta, Walter; Armonda, Rocco; Badjatia, Neeraj; Böesel, Julian; Chesnut, Randall; Chou, Sherry; Claassen, Jan; Czosnyka, Marek; De Georgia, Michael; Figaji, Anthony; Fugate, Jennifer; Helbok, Raimund; Horowitz, David; Hutchinson, Peter; Kumar, Monisha; McNett, Molly; Miller, Chad; Naidech, Andrew; Oddo, Mauro; Olson, DaiWai; O'Phelan, Kristine; Provencio, J Javier; Puppo, Corinna; Riker, Richard; Robertson, Claudia; Schmidt, Michael; Taccone, Fabio

    2014-09-01

    Neurocritical care depends, in part, on careful patient monitoring but as yet there are little data on what processes are the most important to monitor, how these should be monitored, and whether monitoring these processes is cost-effective and impacts outcome. At the same time, bioinformatics is a rapidly emerging field in critical care but as yet there is little agreement or standardization on what information is important and how it should be displayed and analyzed. The Neurocritical Care Society in collaboration with the European Society of Intensive Care Medicine, the Society for Critical Care Medicine, and the Latin America Brain Injury Consortium organized an international, multidisciplinary consensus conference to begin to address these needs. International experts from neurosurgery, neurocritical care, neurology, critical care, neuroanesthesiology, nursing, pharmacy, and informatics were recruited on the basis of their research, publication record, and expertise. They undertook a systematic literature review to develop recommendations about specific topics on physiologic processes important to the care of patients with disorders that require neurocritical care. This review does not make recommendations about treatment, imaging, and intraoperative monitoring. A multidisciplinary jury, selected for their expertise in clinical investigation and development of practice guidelines, guided this process. The GRADE system was used to develop recommendations based on literature review, discussion, integrating the literature with the participants' collective experience, and critical review by an impartial jury. Emphasis was placed on the principle that recommendations should be based on both data quality and on trade-offs and translation into clinical practice. Strong consideration was given to providing pragmatic guidance and recommendations for bedside neuromonitoring, even in the absence of high quality data. PMID:25138226

  5. The International Multidisciplinary Consensus Conference on Multimodality Monitoring in Neurocritical Care: evidentiary tables: a statement for healthcare professionals from the Neurocritical Care Society and the European Society of Intensive Care Medicine.

    PubMed

    Le Roux, Peter; Menon, David K; Citerio, Giuseppe; Vespa, Paul; Bader, Mary Kay; Brophy, Gretchen; Diringer, Michael N; Stocchetti, Nino; Videtta, Walter; Armonda, Rocco; Badjatia, Neeraj; Bösel, Julian; Chesnut, Randall; Chou, Sherry; Claassen, Jan; Czosnyka, Marek; De Georgia, Michael; Figaji, Anthony; Fugate, Jennifer; Helbok, Raimund; Horowitz, David; Hutchinson, Peter; Kumar, Monisha; McNett, Molly; Miller, Chad; Naidech, Andrew; Oddo, Mauro; Olson, DaiWai; O'Phelan, Kristine; Provencio, J Javier; Puppo, Corinna; Riker, Richard; Roberson, Claudia; Schmidt, Michael; Taccone, Fabio

    2014-12-01

    A variety of technologies have been developed to assist decision-making during the management of patients with acute brain injury who require intensive care. A large body of research has been generated describing these various technologies. The Neurocritical Care Society (NCS) in collaboration with the European Society of Intensive Care Medicine (ESICM), the Society for Critical Care Medicine (SCCM), and the Latin America Brain Injury Consortium (LABIC) organized an international, multidisciplinary consensus conference to perform a systematic review of the published literature to help develop evidence-based practice recommendations on bedside physiologic monitoring. This supplement contains a Consensus Summary Statement with recommendations and individual topic reviews on physiologic processes important in the care of acute brain injury. In this article we provide the evidentiary tables for select topics including systemic hemodynamics, intracranial pressure, brain and systemic oxygenation, EEG, brain metabolism, biomarkers, processes of care and monitoring in emerging economies to provide the clinician ready access to evidence that supports recommendations about neuromonitoring. PMID:25608916

  6. High-resolution dynamics of a deep-sea hydrothermal mussel assemblage monitored by the EMSO-Açores MoMAR observatory

    NASA Astrophysics Data System (ADS)

    Sarrazin, J.; Cuvelier, D.; Peton, L.; Legendre, P.; Sarradin, P. M.

    2014-08-01

    Although the spatial distribution of hydrothermal vent assemblages in relation to environmental conditions has been assessed in several studies, there is little documented data on the temporal variation of the fauna and corresponding abiotic factors in a vent community. Here, we present one of the longest integrated (faunal and environmental data) time series ever obtained in a hydrothermal ecosystem. The data were acquired using the TEMPO ecological module that was deployed between 2006 and 2008 on the Mid-Atlantic Ridge, providing the first insights into the day-to-day variations in a Bathymodiolus azoricus mussel assemblage from the Lucky Strike vent field for the 48 days during which the video camera operated. The time-series yielded additional valuable information on longer-term variation in faunal distribution (comparing ~2 years), temperature (11.7 months) and iron concentrations (3.8 months). Results from daily observations showed that the vent mussel assemblage was quite stable over the 48 days of the study, reflecting the relative stability of environmental conditions during this period. B. azoricus mussels appeared to thrive in areas of very limited hydrothermal fluid input in habitats that are, as in other deep-sea ecosystems, significantly influenced by ocean tidal signals. Variation in species abundance was observed but, with the exception of Mirocaris fortunata shrimp, no links could be established with measured environmental variables. Although we did not observe any clear tidal influence on vent fauna, it is likely that physiological processes and species' activities are influenced by these periodic variations. Longer time series are currently being acquired by different experiments deployed on the EMSO-Açores MoMAR observatory (2010-2013 and still recording). They should further improve our knowledge of the dynamics of hydrothermal systems and their associated faunal communities.

  7. Multidisciplinary management: why me?

    PubMed

    Wetenkamp, Vicki

    2002-01-01

    Laboratory professionals are being asked more and more frequently to spread their wings and take on additional responsibilities in the form of multidisciplinary management. Multidisciplinary management can be described as the management of multiple departments with one or more being outside of the traditional laboratory department, such as respiratory care, pharmacy, radiology, or cardiodiagnostics. Reasons behind the trend in multidisciplinary management and why laboratory professionals often are asked to assume these roles will be explored. This column will cover how laboratory managers can prepare for the challenges of multidisciplinary management, what skills are necessary for these new roles, and how to prepare yourself to be the candidate of choice for these positions when they develop. Challenges often encountered will be discussed, including suggestions on how to turn potential difficulties into positive growth experiences. Hopefully, at the conclusion, you will be able to answer the question "Why me?"--either in the form of "Why have I been asked to take on this role?" or "Why might I want to pursue such a role with enthusiasm?" PMID:12046275

  8. Integrating Multidisciplinary Engineering Knowledge

    ERIC Educational Resources Information Center

    Wolff, Karin; Luckett, Kathy

    2013-01-01

    In order to design two distinct engineering qualification levels for an existing University of Technology programme, empirical evidence based on the current diploma is necessary to illuminate the nature of and the relationship between the "contextual" and "conceptual" elements underpinning a multidisciplinary engineering…

  9. Deep-Sea Observatory EMSO-Azores (Lucky Strike, 37º17'N MAR): Impact of Fluid Circulation Pathway on Chemical Hydrothermal Fluxes

    NASA Astrophysics Data System (ADS)

    Chavagnac, V.; Leleu, T.; Boulart, C.; Barreyre, T.; Castillo, A.; Menjot, L.; Cannat, M.; Escartin, J.; Sarradin, P. M.

    2015-12-01

    The operational EMSO-Azores deep-sea observatory provides a unique opportunity combining yearly hydrothermal fluid sampling along with continuous monitoring of physical parameters (temperature, seismicity, pressure,…) to better constrain hydrothermal fluid flow dynamics both in time and space at the Lucky Strike vent field. Repeated sampling at this field since its discovery in the mid 90's shows persistent inter-site differences the end-member hot fluid compositions, revealing 4 groups of sites that possibly reflect various processes, such as phase separation, conductive cooling, tidal pumping, or magmatic activity. Three groups are at the main field, and a fourth one (Capelinhos) is 1,5 km to the E. We also identify a period of high CO2 content of hydrothermal fluids (up to 120 mmol/l), clearly showing replenishment of the magmatic chamber in 2008 and 2010. The Si-Cl geothermobarometer of the most vapor-dominated fluid (270 mmol/l, Capelinhos) gives a pressure of 370 bars and a temperature of ˜435ºC in the reaction zone. If hydrothermal cells operate in a cold hydrostatic pressure gradient, the transition between the reaction and upflow zones is located at about 2400 mbsf, with a magma lens at ˜3400 mbsf. Si-based geothermobarometry and empirical Fe/Mn geothermometry argue for P and T conditions close to seawater critical point at 300 bars (i.e. ˜1300mbsf) for Capelinhos. In contrast, the 3 other groups exhibit temperatures much lower than 380ºC, as well as reduced end-member Fe and Mn concentrations compared to those of Capelinhos. These physico-chemical features reflect the effects of conductive cooling along the upflow zone. Conductive cooling can vary spatially owing to variable substratum permeability across the hydrothermal field, a requisite to induce along-axis oriented hydrothermal cell. The end-member chemical features of the 4 groups suggest that local variations in tectonism and volcanism exert a strong control on heat, mass and chemical fluxes.

  10. Multidisciplinary computational aerosciences

    NASA Technical Reports Server (NTRS)

    Kutler, Paul

    1992-01-01

    As the challenges of single disciplinary computational physics are met, such as computational fluid dynamics, computational structural mechanics, computational propulsion, computational aeroacoustics, computational electromagnetics, etc., scientists have begun investigating the combination of these single disciplines into what is being called multidisciplinary computational aerosciences (MCAS). The combination of several disciplines not only offers simulation realism but also formidable computational challenges. The solution of such problems will require computers orders of magnitude larger than those currently available. Such computer power can only be supplied by massively parallel machines because of the current speed-of-light limitation of conventional serial systems. Even with such machines, MCAS problems will require hundreds of hours for their solution. To efficiently utilize such a machine, research is required in three areas that include parallel architectures, systems software, and applications software. The main emphasis of this paper is the applications software element. Examples that demonstrate application software for multidisciplinary problems currently being solved at NASA Ames Research Center are presented. Pacing items for MCAS are discussed such as solution methodology, physical modeling, computer power, and multidisciplinary validation experiments.

  11. Halitosis: the multidisciplinary approach

    PubMed Central

    Bollen, Curd ML; Beikler, Thomas

    2012-01-01

    Halitosis, bad breath or oral malodour are all synonyms for the same pathology. Halitosis has a large social and economic impact. For the majority of patients suffering from bad breath, it causes embarrassment and affects their social communication and life. Moreover, halitosis can be indicative of underlying diseases. Only a limited number of scientific publications were presented in this field until 1995. Ever since, a large amount of research is published, often with lack of evidence. In general, intraoral conditions, like insufficient dental hygiene, periodontitis or tongue coating are considered to be the most important cause (85%) for halitosis. Therefore, dentists and periodontologists are the first-line professionals to be confronted with this problem. They should be well aware of the origin, the detection and especially of the treatment of this pathology. In addition, ear–nose–throat-associated (10%) or gastrointestinal/endocrinological (5%) disorders may contribute to the problem. In the case of halitophobia, psychiatrical or psychological problems may be present. Bad breath needs a multidisciplinary team approach: dentists, periodontologists, specialists in family medicine, ear–nose–throat surgeons, internal medicine and psychiatry need to be updated in this field, which still is surrounded by a large taboo. Multidisciplinary bad breath clinics offer the best environment to examine and treat this pathology that affects around 25% of the whole population. This article describes the origin, detection and treatment of halitosis, regarded from the different etiological origins. PMID:22722640

  12. GRC RBCC Concept Multidisciplinary Analysis

    NASA Technical Reports Server (NTRS)

    Suresh, Ambady

    2001-01-01

    This report outlines the GRC RBCC Concept for Multidisciplinary Analysis. The multidisciplinary coupling procedure is presented, along with technique validations and axisymmetric multidisciplinary inlet and structural results. The NPSS (Numerical Propulsion System Simulation) test bed developments and code parallelization are also presented. These include milestones and accomplishments, a discussion of running R4 fan application on the PII cluster as compared to other platforms, and the National Combustor Code speedup.

  13. Multidisciplinary research of geothermal modeling

    NASA Astrophysics Data System (ADS)

    -Ing. Ulvi Arslan, Univ., ., Dr. _., Prof.; Heiko Huber, Dipl.-Ing.

    2010-05-01

    application on geothermal systems. The history of this multidisciplinary research of geothermal modeling performed by German universities is shown in this paper. Outstanding geothermal research programs of German universities and state aided organizations (BGR, LBEG, GGA) are pointed out. Actual geothermal modeling programs based on the Finite-Element-Method or the Finite-Differences-Method as well as analytical programs are introduced. National and international geothermal projects supported by German universities and state aided organizations are described. Examples of supervised shallow and deep geothermal systems are given. Actually the Technical University Darmstadt is performing a research program supported by a national organization, the Ministry of Economics and Technology (BMWi). Main aim of this research program titled experimental investigation for the verification of a Finite-Element-Multiphase-Model is to analyze the subsoil as a three-phases-model with separated consideration of conduction, convection and advection and their subsequent interaction. The latest developments of numerical projects as well as the actual state of the before mentioned research program are pointed out in the paper. REFERENCES Quick, H., Arslan, U., Meißner, S., Michael, J. 2007. Deep foundations and geothermal energy - a multi-purpose solution, IFHS: 8. International conference on multi-purpose high-rise towers and tall buildings, Abu Dhabi, 2007 Arslan, U. and Huber, H. 2008. Application of geothermal energy. University of Istanbul, Yapistanbul No. 3 / 2008, Turkey, 2008 Quick, Q., Michael, J., Arslan, U., Huber, H. 2010. History of International Geothermal Power Plants and Geothermal Projects in Germany, Proceedings World Geothermal Congress 2010 Bali, Indonesia, 25-29 April 2010 Arslan, U., Huber, H. 2010. Education of Geothermal Sciences in Germany as part of an application orientated research, Proceedings European Civil Engineering Education and Training (EUCEET III) Special

  14. Multidisciplinary mental health teams.

    PubMed

    Slade, M; Rosen, A; Shankar, R

    1995-01-01

    This study surveyed current practice amongst 91 Indian and Australian staff working within multidisciplinary mental health teams, looking at leadership skills, conflict resolution and therapeutic abilities. Length of training was associated with management skills, though these skill were more developed by psychiatric nurses and occupational therapists working in community settings. Hospital settings involved less consensual decision-making than community teams. Psychiatric nurses spent most time in clinical work, and occupational therapists were rated as less skilled in the therapeutic activities assessed than any other profession. Psychiatrists and clinical psychologists undertook most research. The activities assessed in this study could be undertaken by a team comprising psychiatrists, psychiatric nurses and social workers, with clinical psychologists employed where possible, especially for research or service evaluation. PMID:8847199

  15. Multidisciplinary System Reliability Analysis

    NASA Technical Reports Server (NTRS)

    Mahadevan, Sankaran; Han, Song; Chamis, Christos C. (Technical Monitor)

    2001-01-01

    The objective of this study is to develop a new methodology for estimating the reliability of engineering systems that encompass multiple disciplines. The methodology is formulated in the context of the NESSUS probabilistic structural analysis code, developed under the leadership of NASA Glenn Research Center. The NESSUS code has been successfully applied to the reliability estimation of a variety of structural engineering systems. This study examines whether the features of NESSUS could be used to investigate the reliability of systems in other disciplines such as heat transfer, fluid mechanics, electrical circuits etc., without considerable programming effort specific to each discipline. In this study, the mechanical equivalence between system behavior models in different disciplines are investigated to achieve this objective. A new methodology is presented for the analysis of heat transfer, fluid flow, and electrical circuit problems using the structural analysis routines within NESSUS, by utilizing the equivalence between the computational quantities in different disciplines. This technique is integrated with the fast probability integration and system reliability techniques within the NESSUS code, to successfully compute the system reliability of multidisciplinary systems. Traditional as well as progressive failure analysis methods for system reliability estimation are demonstrated, through a numerical example of a heat exchanger system involving failure modes in structural, heat transfer and fluid flow disciplines.

  16. Breakfast: a multidisciplinary approach

    PubMed Central

    2013-01-01

    Background The role of breakfast as an essential part of an healthy diet has been only recently promoted even if breakfast practices were known since the Middle Age. The growing scientific evidences on this topic are extremely sector-based nevertheless breakfast could be regarded from different point of views and from different expertises. This approach, that take into account history, sociology, anthropology, medicine, psychology and pedagogy, is useful to better understand the value of this meal in our culture. The aim of this paper was to analyse breakfast-related issues based on a multidisciplinary approach with input by specialists from different fields of learning. Discussion Breakfast is now recommended as part of a diet because it is associated with healthier macro- and micronutrient intakes, body mass index and lifestyle. Moreover recent studies showed that breakfast improves cognitive function, intuitive perception and academic performance. Research demonstrates the importance of providing breakfast not only to children but in adults and elderly too. Although the important role breakfast plays in maintaining the health, epidemiological data from industrialised countries reveal that many individuals either eat a nutritionally unhealthy breakfast or skip it completely. Summary The historical, bio-psychological and educational value of breakfast in our culture is extremely important and should be recognized and stressed by the scientific community. Efforts should be done to promote this practice for the individual health and well-being. PMID:23842429

  17. Multidisciplinary care in pediatric oncology

    PubMed Central

    Cantrell, Mary Ann; Ruble, Kathy

    2011-01-01

    This paper describes the significant advances in the treatment of childhood cancer and supportive care that have occurred over the last several decades and details how these advances have led to improved survival and quality of life (QOL) for children with cancer through a multidisciplinary approach to care. Advances in the basic sciences, general medicine, cooperative research protocols, and policy guidelines have influenced and guided the multidisciplinary approach in pediatric oncology care across the spectrum from diagnosis through long-term survival. Two case studies are provided to highlight the nature and scope of multidisciplinary care in pediatric oncology care. PMID:21811384

  18. Lowering Entry Barriers for Multidisciplinary Cyber(e)-Infrastructures

    NASA Astrophysics Data System (ADS)

    Nativi, S.

    2012-04-01

    Multidisciplinarity is more and more important to study the Earth System and address Global Changes. To achieve that, multidisciplinary cyber(e)-infrastructures are an important instrument. In the last years, several European, US and international initiatives have been started to carry out multidisciplinary infrastructures, including: the Spatial Information in the European Community (INSPIRE), the Global Monitoring for Environment and Security (GMES), the Data Observation Network for Earth (DataOne), and the Global Earth Observation System of Systems (GEOSS). The majority of these initiatives are developing service-based digital infrastructures asking scientific Communities (i.e. disciplinary Users and data Producers) to implement a set of standards for information interoperability. For scientific Communities, this has represented an entry barrier which has proved to be high, in several cases. In fact, both data Producers and Users do not seem to be willing to invest precious resources to become expert on interoperability solutions -on the contrary, they are focused on developing disciplinary and thematic capacities. Therefore, an important research topic is lowering entry barriers for joining multidisciplinary cyber(e)-Infrastructures. This presentation will introduce a new approach to achieve multidisciplinary interoperability underpinning multidisciplinary infrastructures and lowering the present entry barriers for both Users and data Producers. This is called the Brokering approach: it extends the service-based paradigm by introducing a new a Brokering layer or cloud which is in charge of managing all the interoperability complexity (e.g. data discovery, access, and use) thus easing Users' and Producers' burden. This approach was successfully experimented in the framework of several European FP7 Projects and in GEOSS.

  19. Giant Serpentine Aneurysms: Multidisciplinary Management

    PubMed Central

    Anshun, W.; Feng, L.; Daming, W.

    2000-01-01

    Summary Sixty-five cases of intracranial giant serpentine aneurysms (GSΛs), including 61 cases reported in the literature and four additional cases presented in this study were reviewed. The clinical presentation, possible causes, natural history, and especially management of GSAs are discussed with emphasis on the need for aggressive intervention and multidisciplinary management. PMID:20667180

  20. Managing Complexity in Multidisciplinary Visualization

    NASA Technical Reports Server (NTRS)

    Miceli, Kristina D.; Lasinski, T. A. (Technical Monitor)

    1995-01-01

    As high performance computing technology progresses, computational simulations are becoming more advanced in their capabilities. In the computational aerosciences domain, single discipline steady-state simulations computed on a single grid are far from the state-of-the-art. In their place are complex, time-dependent multidisciplinary simulations that attempt to model a given geometry more realistically. The product of these multidisciplinary simulations is a massive amount of data stored in different formats, grid topologies, units of measure, etc., as a result of the differences in the simulated physical domains. In addition to the challenges posed by setting up and performing the simulation, additional challenges exist in analyzing computational results. Visualization plays an important role in the advancement of multidisciplinary simulations. To date, visualization has been used to aid in the interpretation of large amounts of simulation data. Because the human visual system is effective in digesting a large amount of information presented graphically, visualization has helped simulation scientists to understand complex simulation results. As these simulations become even more complex, integrating several different physical domains, visualization will be critical to digest the massive amount of information. Another important role for visualization is to provide a common communication medium from which the domain scientists can use to develop, debug, and analyze their work. Multidisciplinary analyses are the next step in simulation technology, not only in computational aerosciences, but in many other areas such as global climate modeling. Visualization researchers must understand and work towards the challenges posed by multidisciplinary simulation scenarios. This paper addresses some of these challenges, describing technologies that must be investigated to create a useful visualization analysis tool for domain scientists.

  1. Recommending Research Profiles for Multidisciplinary Academic Collaboration

    ERIC Educational Resources Information Center

    Gunawardena, Sidath Deepal

    2013-01-01

    This research investigates how data on multidisciplinary collaborative experiences can be used to solve a novel problem: recommending research profiles of potential collaborators to academic researchers seeking to engage in multidisciplinary research collaboration. As the current domain theories of multidisciplinary collaboration are insufficient…

  2. Establishing a framework for building multidisciplinary programs

    PubMed Central

    Meguid, Cheryl; Ryan, Carrie E; Edil, Barish H; Schulick, Richard D; Gajdos, Csaba; Boniface, Megan; Schefter, Tracey E; Purcell, W Thomas; McCarter, Martin

    2015-01-01

    While most providers support the concept of a multidisciplinary approach to patient care, challenges exist to the implementation of successful multidisciplinary clinical programs. As patients become more knowledgeable about their disease through research on the Internet, they seek hospital programs that offer multidisciplinary care. At the University of Colorado Hospital, we utilize a formal multidisciplinary approach across a variety of clinical settings, which has been beneficial to patients, providers, and the hospital. We present a reproducible framework to be used as a guide to develop a successful multidisciplinary program. PMID:26664132

  3. How Multidisciplinary Are the Multidisciplinary Journals Science and Nature?

    PubMed Central

    Solomon, Gregg E. A.; Carley, Stephen; Porter, Alan L.

    2016-01-01

    Interest in cross-disciplinary research knowledge interchange runs high. Review processes at funding agencies, such as the U.S. National Science Foundation, consider plans to disseminate research across disciplinary bounds. Publication in the leading multidisciplinary journals, Nature and Science, may signify the epitome of successful interdisciplinary integration of research knowledge and cross-disciplinary dissemination of findings. But how interdisciplinary are they? The journals are multidisciplinary, but do the individual articles themselves draw upon multiple fields of knowledge and does their influence span disciplines? This research compares articles in three fields (Cell Biology, Physical Chemistry, and Cognitive Science) published in a leading disciplinary journal in each field to those published in Nature and Science. We find comparable degrees of interdisciplinary integration and only modest differences in cross-disciplinary diffusion. That said, though the rate of out-of-field diffusion might be comparable, the sheer reach of Nature and Science, indicated by their potent Journal Impact Factors, means that the diffusion of knowledge therein can far exceed that of leading disciplinary journals in some fields (such as Physical Chemistry and Cognitive Science in our samples). PMID:27043924

  4. Multidisciplinary Care of Laryngeal Cancer.

    PubMed

    Salvador-Coloma, Carmen; Cohen, Ezra

    2016-08-01

    Treatment of larynx cancer has changed dramatically over the past several years. Novel modalities of treatment have been introduced as organ preservation has been developed. In addition, new targeted therapies have appeared, and improvements in radiotherapeutic and surgical techniques have been introduced. Thus, a large variety of treatment options is increasing local control rates and overall survival; however, selecting the most appropriate treatment remains a challenging decision. This article focuses on the multidisciplinary care of early-stage and locally advanced larynx cancer and attempts to sum up different approaches. Moreover, it reviews state-of-the-art treatment in larynx preservation, which has been consolidated in recent years. PMID:27511718

  5. [Multidisciplinary approach to postpartum depression].

    PubMed

    Arranz Lara, Lilia Cristina; Aguirre Rivera, Wilfrido; Ruiz Ornelas, Jaime; Gaviño Ambriz, Salvador; Cervantes Chávez, José Francisco; Carsi Bocanegra, Eduardo; Camacho Díaz, Margarita; Ochoa Madrigal, Martha Georgina

    2008-06-01

    Postpartum depression is a multifactorial condition suffered by 15% of women after delivery. We report a clinical case of a 32 years old female admitted at Postpartum depression clinic of gyneco-obstetric coordination at Centro Médico Nacional 20 de Noviembre, ISSTE, Mexico City. Patient was evaluated by psychiatric and psychological service personnel and diagnosed as with postpartum depression. She was admitted with her child during two weeks to be studied and treated. Several evaluation tests were applied and specific interventions by multidisciplinary team were designed. PMID:18800591

  6. The EuroGEOSS Brokering Framework for Multidisciplinary Interoperability

    NASA Astrophysics Data System (ADS)

    Santoro, M.; Nativi, S.; Craglia, M.; Boldrini, E.; Vaccari, L.; Papeschi, F.; Bigagli, L.

    2011-12-01

    The Global Earth Observation System of Systems (GEOSS), envisioned by the group of eight most industrialized countries (G-8) in 2003, provides the indispensable framework to integrate the Earth observation efforts at a global level. The European Commission also contributes to the implementation of the GEOSS through research projects funded from its Framework Programme for Research & Development. The EuroGEOSS (A European Approach to GEOSS) project was launched on May 2009 for a three-year period with the aim of supporting existing Earth Observing systems and applications interoperability and use within the GEOSS and INSPIRE frameworks. EuroGEOSS developed a multidisciplinary interoperability infrastructure for the three strategic areas of Drought, Forestry and Biodiversity; this operating capacity is currently being extended to other scientific domains (i.e. Climate Change, Water, Ocean, Weather, etc.) Central to the multidisciplinary infrastructure is the "EuroGEOSS Brokering Framework", which is based on a Brokered SOA (Service Oriented Architecture) Approach. This approach extends the typical SOA archetype introducing "expert" components: the Brokers. The Brokers provide the mediation and distribution functionalities needed to interconnect the distributed and heterogeneous resources characterizing a System of Systems (SoS) environment. Such a solution addresses significant shortcomings characterizing the present SOA implementations for global frameworks, such as multiple protocols and data models interoperability. Currently, the EuroGEOSS multidisciplinary infrastructure is composed of the following brokering components: 1. The Discovery Broker: providing harmonized discovery functionalities by mediating and distributing user queries against tens of heterogeneous services. 2. The Semantic Discovery Augmentation Component: enhancing the capabilities of the discovery broker with semantic query-expansion. 3. The Data Access Broker: enabling users to seamlessly

  7. [Anorexia nervosa: a multidisciplinary approach].

    PubMed

    Bastidas, A; Cantó, T; Font, E

    2000-06-01

    The childhood-adolescent psychiatrics field has, for various years, been confronted by a very significant increase in cases of nervous anorexia, a serious eating disorder characterized by a noticeable loss of weight. At the bottom of this situation lie complex biological, psychological and social-cultural problems, which demand an interdisciplinary approach to solve them. This article presents the predisposing factors, the initial factors, the factors which maintain this disorder...; what behaviors are considered to be normal; what the physical and psychological manifestations are; as well as what the medical evaluation carried out is ... to finalize with an explanation of the different functions to be performed by each member of a multidisciplinary team. PMID:10983149

  8. NPSS Multidisciplinary Integration and Analysis

    NASA Technical Reports Server (NTRS)

    Hall, Edward J.; Rasche, Joseph; Simons, Todd A.; Hoyniak, Daniel

    2006-01-01

    The objective of this task was to enhance the capability of the Numerical Propulsion System Simulation (NPSS) by expanding its reach into the high-fidelity multidisciplinary analysis area. This task investigated numerical techniques to convert between cold static to hot running geometry of compressor blades. Numerical calculations of blade deformations were iteratively done with high fidelity flow simulations together with high fidelity structural analysis of the compressor blade. The flow simulations were performed with the Advanced Ducted Propfan Analysis (ADPAC) code, while structural analyses were performed with the ANSYS code. High fidelity analyses were used to evaluate the effects on performance of: variations in tip clearance, uncertainty in manufacturing tolerance, variable inlet guide vane scheduling, and the effects of rotational speed on the hot running geometry of the compressor blades.

  9. Pediatric pain management: the multidisciplinary approach

    PubMed Central

    Odell, Shannon; Logan, Deirdre E

    2013-01-01

    Chronic pain in children and adolescents is a growing problem and one that is increasingly being addressed with multidisciplinary treatment teams. This review summarizes different multidisciplinary clinics, focusing specifically on intensive pediatric pain rehabilitation centers. This review offers a summary of the challenges faced by these programs and areas for future study. PMID:24250232

  10. Multi-Disciplinary Consumer Education Curriculum.

    ERIC Educational Resources Information Center

    Sie, Maureen A.; And Others

    Two activities are described in this report, both of which focus on the multi-disciplinary approach in the development of a consumer education curriculum for high school students. The first activity, which demonstrated the feasibility of a multi-disciplinary approach using local school personnel and resources and university faculty in curriculum…

  11. Geophysical monitoring from seafloor observatories in Italian volcanic sites: Marsili Seamount, Etna Volcano and Stromboli Island.

    NASA Astrophysics Data System (ADS)

    Giovanetti, Gabriele; Monna, Stephen; Lo Bue, Nadia; Embriaco, Davide; Frugoni, Francesco; Marinaro, Giuditta; De Caro, Mariagrazia; Sgroi, Tiziana; Montuori, Caterina; De Santis, Angelo; Cianchini, Gianfranco; Favali, Paolo; Beranzoli, Laura

    2016-04-01

    Many volcanoes on Earth are located within or near the oceans and observations from the seafloor can be very important for a more complete understanding of the structure and nature of these volcanoes. We present some results obtained from data acquired in volcanic sites in the Central Mediterranean Sea. Data were taken by means of stand-alone free-fall systems, and fixed-point ocean observatories, both cabled and autonomous, some of which are part of the European research infrastructure EMSO (European Multidisciplinary Seafloor and water-column Observatory, www.emso-eu.org). EMSO observatories strongly rely on a multidisciplinary approach, in spite of the many technical challenges that the operation of very different sensors by means of a single acquisition system presents. We focus on three volcanic sites near the coasts of Italy (Marsili seamount, Stromboli Island and Etna Volcano) involved in subduction processes and to the opening of the Central Mediterranean basin. Through multidisciplinary analysis we were able to associate geophysical and oceanographic signals to a common volcanic source in a more reliable way with respect to single sensor analysis, showing the potential of long-term seafloor monitoring in unravelling otherwise still obscure aspects of such volcanoes. The very strong expansion of seafloor monitoring, which is taking place both in the quantity of the infrastructures and in the technological capabilities, suggests that there will be important developments in the near future.

  12. Temporomandibular joint multidisciplinary team clinic.

    PubMed

    Ahmed, Nabeela; Poate, Tim; Nacher-Garcia, Cristina; Pugh, Nicola; Cowgill, Helen; Page, Lisa; Matthews, N Shaun

    2014-11-01

    Patients with dysfunction of the temporomandibular joint (TMJ) commonly present to oral and maxillofacial departments and are increasingly being managed by a subspecialist group of surgeons. We review the outcomes of patients attending a specialist TMJ multidisciplinary team (MDT) clinic. All patients are simultaneously reviewed by a consultant oral and maxillofacial surgeon, consultant in oral medicine, specialist physiotherapist, and maxillofacial prosthetist, and they can also see a consultant liaison psychiatrist. They are referred from primary, secondary, and tertiary care when medical and surgical treatment in the routine TMJ clinic has failed, and are triaged by the attending maxillofacial surgeon. On discharge they are returned to the care of the referring practitioner. We review the outcomes of patients attending this clinic over a 2-year period and show improvements in pain scores and maximal incisal opening, as well as quality of life outcome measures. All units in the UK with an interest in the management of diseases of the TMJ should consider establishing this type of clinic and should use available resources and expertise to maximise outcomes. PMID:25179688

  13. Pineal lesions: a multidisciplinary challenge.

    PubMed

    Westphal, Manfred; Emami, Pedram

    2015-01-01

    The pineal region is a complex anatomical compartment, harbouring the pineal gland surrounded by the quadrigeminal plate and the confluents of the internal cerebral veins to form the vein of Galen. The complexity of lesions in that region, however, goes far beyond the pineal parenchyma proper. Originating in the pineal gland, there are not only benign cysts but also numerous different tumour types. In addition, lesions such as tectal gliomas, tentorial meningiomas and choroid plexus papillomas arise from the surrounding structures, occupying that regions. Furthermore, the area has an affinity for metastatic lesions. Vascular lesions complete the spectrum mainly as small tectal arteriovenous malformations or cavernous haemangiomas.Taken together, there is a wide spectrum of lesions, many unique to that region, which call for a multidisciplinary approach. The limited access and anatomical complexity have generated a spectrum of anatomical approaches and raised the interest for neuroendoscopic approaches. Equally complex is the spectrum of treatment modalities such as microsurgery as the main option but stereotactic radiosurgery as an alternative or adjuvant to surgery for selected cases, radiation as for germinoma (see below) and or combinatorial chemotherapy, which may need to precede any other ablative technique as constituents.In this context, we review the current literature and our own series to obtain a snapshot sentiment of how to approach pineal lesions, how to interrelate alternative/competing concepts and review the recent technological advances. PMID:25411146

  14. Multidisciplinary approaches to solar hydrogen

    PubMed Central

    Bren, Kara L.

    2015-01-01

    This review summarizes three different approaches to engineering systems for the solar-driven evolution of hydrogen fuel from water: molecular, nanomaterials and biomolecular. Molecular systems have the advantage of being highly amenable to modification and detailed study and have provided great insight into photophysics, electron transfer and catalytic mechanism. However, they tend to display poor stability. Systems based on nanomaterials are more robust but also are more difficult to synthesize in a controlled manner and to modify and study in detail. Biomolecular systems share many properties with molecular systems and have the advantage of displaying inherently high efficiencies for light absorption, electron–hole separation and catalysis. However, biological systems must be engineered to couple modules that capture and convert solar photons to modules that produce hydrogen fuel. Furthermore, biological systems are prone to degradation when employed in vitro. Advances that use combinations of these three tactics also are described. Multidisciplinary approaches to this problem allow scientists to take advantage of the best features of biological, molecular and nanomaterials systems provided that the components can be coupled for efficient function. PMID:26052425

  15. Multidisciplinary Management of Laryngeal Carcinoma

    SciTech Connect

    Mendenhall, William M. Mancuso, Anthony A.; Hinerman, Russell W.; Malyapa, Robert S.; Werning, John W.; Amdur, Robert J.; Villaret, Douglas B.

    2007-10-01

    The management of head and neck cancer has evolved into a multidisciplinary approach in which patients are evaluated before treatment and decisions depend on prospective multi-institutional trials, as well as retrospective outcome studies. The choice of one or more modalities to use in a given case varies with the tumor site and extent, as exemplified in the treatment of laryngeal squamous cell carcinomas. The goals of treatment include cure, laryngeal voice preservation, voice quality, optimal swallowing, and minimal xerostomia. Treatment options include transoral laser excision, radiotherapy (both definitive and postoperative), open partial laryngectomy, total laryngectomy, and neck dissection. The likelihood of local control and preservation of laryngeal function is related to tumor volume. Patients who have a relatively high risk of local recurrence undergo follow-up computed tomography scans every 3-4 months for the first 2 years after radiotherapy. Patients with suspicious findings on computed tomography might benefit from fluorodeoxyglucose positron emission tomography to differentiate post-radiotherapy changes from tumor.

  16. Teams: communication in multidisciplinary care.

    PubMed

    Penson, Richard T; Kyriakou, Helena; Zuckerman, Dan; Chabner, Bruce A; Lynch, Thomas J

    2006-05-01

    Shortly before his death in 1995, Kenneth B. Schwartz, a cancer patient at Massachusetts General Hospital (MGH), founded The Kenneth B. Schwartz Center at MGH. The Schwartz Center is a nonprofit organization dedicated to supporting and advancing compassionate health care delivery that provides hope to the patient and support to caregivers, and encourages the healing process. The Center sponsors the Schwartz Center Rounds, a monthly multidisciplinary forum where caregivers reflect on important psychosocial issues faced by patients, their families, and their caregivers, and gain insight and support from fellow staff members. The evolving field of oncology increasingly requires a team of medical specialists working in unison to deliver optimal medical care. While this coordination may maximize the technical synergy of care, it can challenge interprofessional and interdisciplinary connections. Poor and miscommunication and conflicts between staff and between the family and providers adversely affect patient care and quality of life. Furthermore, lack of communication leaves a vacuum that sucks in fear. A recent Newsweek article highlighted the challenges of practicing in the age of high-tech medicine. The author had to beg for a prognosis for her critically ill and dying husband, with unhelpful subspecialists failing to communicate the bigger picture. This article explores the tough issue of how teams handle uncertainty and bad news and how patients and families can be better supported in the multifaceted paradigm of modern care. PMID:16720852

  17. Multidisciplinary approaches to solar hydrogen.

    PubMed

    Bren, Kara L

    2015-06-01

    This review summarizes three different approaches to engineering systems for the solar-driven evolution of hydrogen fuel from water: molecular, nanomaterials and biomolecular. Molecular systems have the advantage of being highly amenable to modification and detailed study and have provided great insight into photophysics, electron transfer and catalytic mechanism. However, they tend to display poor stability. Systems based on nanomaterials are more robust but also are more difficult to synthesize in a controlled manner and to modify and study in detail. Biomolecular systems share many properties with molecular systems and have the advantage of displaying inherently high efficiencies for light absorption, electron-hole separation and catalysis. However, biological systems must be engineered to couple modules that capture and convert solar photons to modules that produce hydrogen fuel. Furthermore, biological systems are prone to degradation when employed in vitro. Advances that use combinations of these three tactics also are described. Multidisciplinary approaches to this problem allow scientists to take advantage of the best features of biological, molecular and nanomaterials systems provided that the components can be coupled for efficient function. PMID:26052425

  18. The MED-SUV Multidisciplinary Interoperability Infrastructure

    NASA Astrophysics Data System (ADS)

    Mazzetti, Paolo; D'Auria, Luca; Reitano, Danilo; Papeschi, Fabrizio; Roncella, Roberto; Puglisi, Giuseppe; Nativi, Stefano

    2016-04-01

    In accordance with the international Supersite initiative concept, the MED-SUV (MEDiterranean SUpersite Volcanoes) European project (http://med-suv.eu/) aims to enable long-term monitoring experiment in two relevant geologically active regions of Europe prone to natural hazards: Mt. Vesuvio/Campi Flegrei and Mt. Etna. This objective requires the integration of existing components, such as monitoring systems and data bases and novel sensors for the measurements of volcanic parameters. Moreover, MED-SUV is also a direct contribution to the Global Earth Observation System of Systems (GEOSS) as one the volcano Supersites recognized by the Group on Earth Observation (GEO). To achieve its goal, MED-SUV set up an advanced e-infrastructure allowing the discovery of and access to heterogeneous data for multidisciplinary applications, and the integration with external systems like GEOSS. The MED-SUV overall infrastructure is conceived as a three layer architecture with the lower layer (Data level) including the identified relevant data sources, the mid-tier (Supersite level) including components for mediation and harmonization , and the upper tier (Global level) composed of the systems that MED-SUV must serve, such as GEOSS and possibly other global/community systems. The Data level is mostly composed of existing data sources, such as space agencies satellite data archives, the UNAVCO system, the INGV-Rome data service. They share data according to different specifications for metadata, data and service interfaces, and cannot be changed. Thus, the only relevant MED-SUV activity at this level was the creation of a MED-SUV local repository based on Web Accessible Folder (WAF) technology, deployed in the INGV site in Catania, and hosting in-situ data and products collected and generated during the project. The Supersite level is at the core of the MED-SUV architecture, since it must mediate between the disparate data sources in the layer below, and provide a harmonized view to

  19. Localized Pancreatic Cancer: Multidisciplinary Management.

    PubMed

    Coveler, Andrew L; Herman, Joseph M; Simeone, Diane M; Chiorean, E Gabriela

    2016-01-01

    Pancreatic cancer is an aggressive cancer that continues to have single-digit 5-year mortality rates despite advancements in the field. Surgery remains the only curative treatment; however, most patients present with late-stage disease deemed unresectable, either due to extensive local vascular involvement or the presence of distant metastasis. Resection guidelines that include a borderline resectable group, as well as advancements in neoadjuvant chemotherapy and radiation that improve resectability of locally advanced disease, may improve outcomes for patients with more invasive disease. Multi-agent chemotherapy regimens fluorouracil, leucovorin, irinotecan, and oxaliplatin (FOLFIRINOX) and nab-paclitaxel with gemcitabine improved response rates and survival in metastatic pancreatic cancer and are now being used in earlier stages for patients with localized potentially resectable and unresectable disease, with goals of downstaging tumors to allow margin-negative resection and reducing systemic recurrence. Chemoradiotherapy, although still controversial for both resectable and unresectable pancreatic cancer, is being used in the context of contemporary chemotherapy backbone regimens, and novel radiation techniques such as stereotactic body frame radiation therapy (SBRT) are studied on the premise of maintaining or improving efficacy and reducing treatment duration. Patient selection for optimal treatment designation is currently provided by multidisciplinary tumor boards, but biomarker discovery, in blood, tumors, or through novel imaging, is an area of intense research. Results to date suggest that some patients with unresectable disease at the outset have survival rates as good as those with initially resectable disease if able to undergo surgical resection. Long-term follow-up and improved clinical trials options are needed to determine optimal treatment modalities for patients with localized pancreatic cancer. PMID:27249726

  20. Multidisciplinary Design and Analysis for Commercial Aircraft

    NASA Technical Reports Server (NTRS)

    Cummings, Russell M.; Freeman, H. JoAnne

    1999-01-01

    Multidisciplinary design and analysis (MDA) has become the normal mode of operation within most aerospace companies, but the impact of these changes have largely not been reflected at many universities. On an effort to determine if the emergence of multidisciplinary design concepts should influence engineering curricula, NASA has asked several universities (Virginia Tech, Georgia Tech, Clemson, BYU, and Cal Poly) to investigate the practicality of introducing MDA concepts within their undergraduate curricula. A multidisciplinary team of faculty, students, and industry partners evaluated the aeronautical engineering curriculum at Cal Poly. A variety of ways were found to introduce MDA themes into the curriculum without adding courses or units to the existing program. Both analytic and educational tools for multidisciplinary design of aircraft have been developed and implemented.

  1. The Brokering Approach for Multidisciplinary Data Discovery and Access

    NASA Astrophysics Data System (ADS)

    Nativi, Stefano

    2013-04-01

    Global sustainability research requires an integrated multidisciplinary effort underpinned by a collaborative environment discovering and accessing heterogeneous data across disciplines. Traditionally, interoperability has been achieved by implementing federation of systems. The federating approach entails the adoption of a set of common technologies and standards. This presentation argues that for complex (and uncontrolled) environments such as global, multidisciplinary, and voluntary-based infrastructures, federated solutions proved not to be well-accepted. In fact, the adoption of a limited common set of technologies and standards raises a couple of important issues: (a) high level entry barriers for both data producers and users; (b) lack of appropriateness to address domain specificities. More recently, a new interoperability approach was successfully experimented: the brokering approach. This presentation identifies the principles of brokering, and gives examples of practical implementation relating to data discovery, semantic searching, and data access. The benefit of the brokering approach includes: (a) lowers barriers to participation in distributed systems for both users and resource providers (minimal burden or cost impact on existing systems); (b) accelerates interconnection of disparate systems; (c) facilitates sustainability, reusability, extensibility, and flexibility of multidisciplinary infrastructures; (d) removes need to impose common (e.g. federal, "top-down") specifications and software components enabling a more adaptive "bottom-up" evolution of infrastructures. The Brokering approach was considered and successfully adopted by cross-disciplinary initiatives (e.g. GEOSS: Global Earth Observation System of Systems; several European FP7 programmes, NSIDC, etc. ); recently, the NSF EarthCube initiative funded a project dealing with "Data Broker".

  2. The Brokering Approach for Multidisciplinary Data Discovery and Access

    NASA Astrophysics Data System (ADS)

    Nativi, S.

    2012-12-01

    Global sustainability research requires an integrated multidisciplinary effort underpinned by a collaborative environment discovering and accessing heterogeneous data across disciplines. Traditionally, interoperability has been achieved by implementing federation of systems. The federating approach entails the adoption of a set of common technologies and standards. This presentation argues that for complex (and uncontrolled) environments such as global, multidisciplinary, and voluntary-based infrastructures, federated solutions proved not to be well-accepted. In fact, the adoption of a limited common set of technologies and standards raises a couple of important issues: (a) high level entry barriers for both data producers and users; (b) lack of appropriateness to address domain specificities. Recently, a new interoperability approach was successfully experimented: the brokering approach. This presentation identifies the principles of brokering, and gives examples of practical implementation relating to data discovery, semantic searching, and data access. The benefit of the brokering approach includes: (a) lowers barriers to participation in distributed systems for both users and resource providers (minimal burden or cost impact on existing systems); (b) accelerates interconnection of disparate systems; (c) facilitates sustainability, reusability, extensibility, and flexibility of multidisciplinary infrastructures; (d) removes need to impose common (e.g. federal, "top-down") specifications and software components enabling a more adaptive "bottom-up" evolution of infrastructures. The Brokering approach was successfully analyzed and used by cross-disciplinary initiatives (e.g. GEOSS: Global Earth Observation System of Systems; several European FP7 programmes, NSIDC, etc. ); recently, the NSF EarthCube initiative funded a project dealing with "Data Broker".

  3. United States History: A Multi-Ethnic, Non-Sexist, Multi-Disciplinary Resource Guide for High School Teachers.

    ERIC Educational Resources Information Center

    Hohenfeldt, Harold H., Ed.

    The first part of this resource guide is designed to help secondary teachers provide a multi-ethnic/non-sexist thrust to United States history. The second part will help them develop a multi-disciplinary approach to U.S. history. Part one is organized by the following ethnic groups: Blacks, Asians, Europeans, Hispanics, Jews, American Indians, and…

  4. Advances in Multi-disciplinary Interoperability

    NASA Astrophysics Data System (ADS)

    Pearlman, J.; Nativi, S.; Craglia, M.; Huerta, J.; Rubio-Iglesias, J. M.; Serrano, J. J.

    2012-04-01

    The challenge for addressing issues such as climate change, food security or ecosystem sustainability is that they require multi-disciplinary collaboration and the ability to integrate information across scientific domains. Multidisciplinary collaborations are difficult because each discipline has its own "language", protocols and formats for communicating within its community and handling data and information. EuroGEOSS demonstrates the added value to the scientific community and to society of making existing systems and applications interoperable and useful within the GEOSS and INSPIRE frameworks. In 2010, the project built an initial operating capacity of a multi-disciplinary Information System addressing three areas: drought, forestry and biodiversity. It is now furthering this development into an advanced operating capacity (http://www.eurogeoss.eu). The key to this capability is the creation of a broker that supports access to multiple resources through a common user interface and the automation of data search and access using state of the art information technology. EuroGEOSS hosted a conference on information systems and multi-disciplinary applications of science and technology. "EuroGEOSS: advancing the vision of GEOSS" provided a forum for developers, users and decision-makers working with advanced multi-disciplinary information systems to improve science and decisions for complex societal issues. In particular, the Conference addressed: Information systems for supporting multi-disciplinary research; Information systems and modeling for biodiversity, drought, forestry and related societal benefit areas; and Case studies of multi-disciplinary applications and outcomes. This paper will discuss the major finding of the conference and the directions for future development.

  5. Multidisciplinary Concurrent Design Optimization via the Internet

    NASA Technical Reports Server (NTRS)

    Woodard, Stanley E.; Kelkar, Atul G.; Koganti, Gopichand

    2001-01-01

    A methodology is presented which uses commercial design and analysis software and the Internet to perform concurrent multidisciplinary optimization. The methodology provides a means to develop multidisciplinary designs without requiring that all software be accessible from the same local network. The procedures are amenable to design and development teams whose members, expertise and respective software are not geographically located together. This methodology facilitates multidisciplinary teams working concurrently on a design problem of common interest. Partition of design software to different machines allows each constituent software to be used on the machine that provides the most economy and efficiency. The methodology is demonstrated on the concurrent design of a spacecraft structure and attitude control system. Results are compared to those derived from performing the design with an autonomous FORTRAN program.

  6. Multidisciplinary Approach to Linear Aerospike Nozzle Optimization

    NASA Technical Reports Server (NTRS)

    Korte, J. J.; Salas, A. O.; Dunn, H. J.; Alexandrov, N. M.; Follett, W. W.; Orient, G. E.; Hadid, A. H.

    1997-01-01

    A model of a linear aerospike rocket nozzle that consists of coupled aerodynamic and structural analyses has been developed. A nonlinear computational fluid dynamics code is used to calculate the aerodynamic thrust, and a three-dimensional fink-element model is used to determine the structural response and weight. The model will be used to demonstrate multidisciplinary design optimization (MDO) capabilities for relevant engine concepts, assess performance of various MDO approaches, and provide a guide for future application development. In this study, the MDO problem is formulated using the multidisciplinary feasible (MDF) strategy. The results for the MDF formulation are presented with comparisons against sequential aerodynamic and structural optimized designs. Significant improvements are demonstrated by using a multidisciplinary approach in comparison with the single- discipline design strategy.

  7. Multidisciplinary management for esophageal and gastric cancer

    PubMed Central

    Boniface, Megan M; Wani, Sachin B; Schefter, Tracey E; Koo, Phillip J; Meguid, Cheryl; Leong, Stephen; Kaplan, Jeffrey B; Wingrove, Lisa J; McCarter, Martin D

    2016-01-01

    The management of esophageal and gastric cancer is complex and involves multiple specialists in an effort to optimize patient outcomes. Utilizing a multidisciplinary team approach starting from the initial staging evaluation ensures that all members are in agreement with the plan of care. Treatment selection for esophageal and gastric cancer often involves a combination of chemotherapy, radiation, surgery, and palliative interventions (endoscopic and surgical), and direct communication between specialists in these fields is needed to ensure appropriate clinical decision making. At the University of Colorado, the Esophageal and Gastric Multidisciplinary Clinic was created to bring together all experts involved in treating these diseases at a weekly conference in order to provide patients with coordinated, individualized, and patient-centered care. This review details the essential elements and benefits of building a multidisciplinary program focused on treating esophageal and gastric cancer patients. PMID:27217796

  8. Multidisciplinary Approach to Aerospike Nozzle Design

    NASA Technical Reports Server (NTRS)

    Korte, J. J.; Salas, A. O.; Dunn, H. J.; Alexandrov, N. M.; Follett, W. W.; Orient, G. E.; Hadid, A. H.

    1997-01-01

    A model of a linear aerospike rocket nozzle that consists of coupled aerodynamic and structural analyses has been developed. A nonlinear computational fluid dynamics code is used to calculate the aerodynamic thrust, and a three-dimensional finite-element model is used to determine the structural response and weight. The model will be used to demonstrate multidisciplinary design optimization (MDO) capabilities for relevant engine concepts, assess performance of various MDO approaches, and provide a guide for future application development. In this study, the MDO problem is formulated using the multidisciplinary feasible (MDF) strategy. The results for the MDF formulation are presented with comparisons against separate aerodynamic and structural optimized designs. Significant improvements are demonstrated by using a multidisciplinary approach in comparison with the single-discipline design strategy.

  9. Stronger Disciplinary Identities in Multidisciplinary Research Schools

    ERIC Educational Resources Information Center

    Geschwind, Lars; Melin, Göran

    2016-01-01

    In this study, two multidisciplinary Social Sciences and Humanities research schools in Sweden have been investigated regarding disciplinary identity-making. This study investigates the meetings between different disciplines around a common thematic area of study for Ph.D. students. The Ph.D. students navigate through a complex social and…

  10. 34 CFR 303.17 - Multidisciplinary.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Multidisciplinary. 303.17 Section 303.17 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION EARLY INTERVENTION PROGRAM FOR INFANTS AND TODDLERS...

  11. International Multidisciplinary Artificial Gravity (IMAG) Project

    NASA Technical Reports Server (NTRS)

    Laurini, Kathy

    2007-01-01

    This viewgraph presentation reviews the efforts of the International Multidisciplinary Artificial Gravity Project. Specifically it reviews the NASA Exploration Planning Status, NASA Exploration Roadmap, Status of Planning for the Moon, Mars Planning, Reference health maintenance scenario, and The Human Research Program.

  12. Thoughts about multidisciplinary, interdisciplinary, and transdisciplinary research.

    PubMed

    Fawcett, Jacqueline

    2013-10-01

    This essay focuses on multidisciplinary, interdisciplinary, and transdisciplinary research. The definitions and objectives for these three types of multiple discipline research are given. Discussion centers on the gains and losses that may be experienced by individual nurses who engage in such research, as well as gains and losses for the discipline of nursing. PMID:24085679

  13. The Taliesin Project: Multidisciplinary Education and Multimedia.

    ERIC Educational Resources Information Center

    Smith, Eric E.; Westhoff, Guy M.

    1992-01-01

    Describes the Taliesin Project, a current curriculum materials research and development effort whose main goals are (1) the development of a computer-aided classroom instructional tool for grades six through eight based on hypermedia technology, and (2) the development of a multidisciplinary curriculum to help develop stronger interests in…

  14. Placenta accreta and anesthesia: A multidisciplinary approach

    PubMed Central

    Khokhar, RS; Baaj, J; Khan, MU; Dammas, FA; Rashid, N

    2016-01-01

    Placenta accreta (an abnormally adherent placenta) is one of the two leading causes of peripartum hemorrhage and the most common indication for peripartum hysterectomy. Placenta accreta may be associated with significant maternal hemorrhage at delivery owing to the incomplete placental separation. When placenta accreta is diagnosed before delivery, a multidisciplinary approach may improve patient outcome. PMID:27375391

  15. Evaluating Multidisciplinary Education in Health Care.

    ERIC Educational Resources Information Center

    Pirrie, Anne; Wilson, Valerie; Elsegood, John; Hall, John; Hamilton, Sheila; Harden, Ronald; Lee, Diana; Stead, Joan

    A 2-year study evaluated students' and course organizers' perceptions of the effectiveness of multidisciplinary education (ME) in health care and factors that facilitate or inhibit its development. The study had three phases: a survey of ME provision in the United Kingdom; 42 qualitative interviews and focus groups in 14 sites; and data feedback.…

  16. Multidisciplinary approaches to climate change questions

    USGS Publications Warehouse

    Middleton, Beth A.

    2011-01-01

    Multidisciplinary approaches are required to address the complex environmental problems of our time. Solutions to climate change problems are good examples of situations requiring complex syntheses of ideas from a vast set of disciplines including science, engineering, social science, and the humanities. Unfortunately, most ecologists have narrow training, and are not equipped to bring their environmental skills to the table with interdisciplinary teams to help solve multidisciplinary problems. To address this problem, new graduate training programs and workshops sponsored by various organizations are providing opportunities for scientists and others to learn to work together in multidisciplinary teams. Two examples of training in multidisciplinary thinking include those organized by the Santa Fe Institute and Dahlem Workshops. In addition, many interdisciplinary programs have had successes in providing insight into climate change problems including the International Panel on Climate Change, the Joint North American Carbon Program, the National Academy of Science Research Grand Challenges Initiatives, and the National Academy of Science. These programs and initiatives have had some notable success in outlining some of the problems and solutions to climate change. Scientists who can offer their specialized expertise to interdisciplinary teams will be more successful in helping to solve the complex problems related to climate change.

  17. Directions in Environmental Gerontology: A Multidisciplinary Field

    ERIC Educational Resources Information Center

    Kendig, Hal

    2003-01-01

    This article considers developments and directions for environmental gerontology drawing on the three papers in this Forum. The multidisciplinary field came of age during the 1960s with Powell Lawton's powerful environmental press paradigm and its applications to empirical research and building design. Recent theoretical developments in Europe and…

  18. OECI accreditation at Veneto Institute of Oncology IOV - IRCCS, general framework and multidisciplinary approach.

    PubMed

    Chiusole, Daniela; Cioffredi, Piero; Basso, Umberto; Bortolami, Alberto; Crivellari, Gino; Gennaro, Gisella; Spina, Romina; Opocher, Giuseppe

    2015-01-01

    The aim of this article is to describe the accreditation process of the Veneto Institute of Oncology (IOV-IRCCS) according to the Organisation of European Cancer Institutes (OECI) model, with particular reference to the standards for the multidisciplinary approach. Through the analysis of the process and the activities of each multidisciplinary team (MDT) and the development, at a regional level, of diagnostic, therapeutic, and care pathways (PDTA), all the necessary steps to meet the OECI standards have been determined. Adjustment is ongoing. We are working on the inclusion of the MDT registration forms in the electronic medical records and on the possibility to extend the OECI model to the MDT not based at IOV, but participated in by IOV professionals. The sarcoma MDT has achieved results demonstrating that the OECI framework has allowed the professionals involved in the multidisciplinary meeting to systematically share the clinical information of the patient, who can benefit from better continuity of care. The model has also provided greater clarity in the management of patients who are enrolled in clinical trials and deviate from Guide Lines (GL)/PDTA. The accreditation process according to the OECI model has added value to the IOV's already well-developed multidisciplinary activities. PMID:27096271

  19. A Multidisciplinary Approach to Sustainable Management of Watershed Resources

    EPA Science Inventory

    The lack of integration in the study and management of water resource problems suggests the need for a multidisciplinary approach. As practiced in the Shepherd Creek stormwater management study (Cincinnati OH), we envision a multidisciplinary approach involving economic incentive...

  20. European Mistletoe

    MedlinePlus

    ... gov Key References American mistletoe. Natural Medicines Comprehensive Database Web site. Accessed at www.naturaldatabase.com on July 7, 2009. European mistletoe. Natural Medicines Comprehensive Database Web site. Accessed at www.naturaldatabase.com on July ...

  1. Initial Multidisciplinary Design and Analysis Framework

    NASA Technical Reports Server (NTRS)

    Ozoroski, L. P.; Geiselhart, K. A.; Padula, S. L.; Li, W.; Olson, E. D.; Campbell, R. L.; Shields, E. W.; Berton, J. J.; Gray, J. S.; Jones, S. M.; Naiman, C. G.; Seidel, J. A.; Moore, K. T.; Naylor, B. A.; Townsend, S.

    2010-01-01

    Within the Supersonics (SUP) Project of the Fundamental Aeronautics Program (FAP), an initial multidisciplinary design & analysis framework has been developed. A set of low- and intermediate-fidelity discipline design and analysis codes were integrated within a multidisciplinary design and analysis framework and demonstrated on two challenging test cases. The first test case demonstrates an initial capability to design for low boom and performance. The second test case demonstrates rapid assessment of a well-characterized design. The current system has been shown to greatly increase the design and analysis speed and capability, and many future areas for development were identified. This work has established a state-of-the-art capability for immediate use by supersonic concept designers and systems analysts at NASA, while also providing a strong base to build upon for future releases as more multifidelity capabilities are developed and integrated.

  2. Multidisciplinary Optimization Methods for Aircraft Preliminary Design

    NASA Technical Reports Server (NTRS)

    Kroo, Ilan; Altus, Steve; Braun, Robert; Gage, Peter; Sobieski, Ian

    1994-01-01

    This paper describes a research program aimed at improved methods for multidisciplinary design and optimization of large-scale aeronautical systems. The research involves new approaches to system decomposition, interdisciplinary communication, and methods of exploiting coarse-grained parallelism for analysis and optimization. A new architecture, that involves a tight coupling between optimization and analysis, is intended to improve efficiency while simplifying the structure of multidisciplinary, computation-intensive design problems involving many analysis disciplines and perhaps hundreds of design variables. Work in two areas is described here: system decomposition using compatibility constraints to simplify the analysis structure and take advantage of coarse-grained parallelism; and collaborative optimization, a decomposition of the optimization process to permit parallel design and to simplify interdisciplinary communication requirements.

  3. [Integrated multidisciplinary treatment modalities for obesity].

    PubMed

    Yu, Jian-chun

    2010-02-01

    The rapid increase of obesity nationwide and worldwide has threatened human health and caused the increase of metabolic diseases and the changes of disease spectrum. Its co-morbidities, mortality, and relevant socio-economic issues have became global concerns. Integrated multidisciplinary treatment modalities have emerged in recent years. For severely obese patients body mass index (BMI>40 kg/m(2) or obese patients (BMI 35 - 40 kg/m(2)) with co-morbidities such as severe diabetes, obesity-associated cardiac lesions, severe sleep apnea, infertility, and osteoarthritis that affect the daily life, minimally invasive laparoscopic bariatric surgery (such as Lap Banding) can achieve satisfactory results by reducing body weight in long term, treating or preventing the co-morbidities, and ultimately decreasing mortality. Multidisciplinary treatment modalities for tumors, obesity, and other diseases have been widely adopted. This strategy may play increasingly important roles in improving the treatment effectiveness, upgrading healthcare services, and addressing interdisciplinary problems. PMID:20236577

  4. Convergence Estimates for Multidisciplinary Analysis and Optimization

    NASA Technical Reports Server (NTRS)

    Arian, Eyal

    1997-01-01

    A quantitative analysis of coupling between systems of equations is introduced. This analysis is then applied to problems in multidisciplinary analysis, sensitivity, and optimization. For the sensitivity and optimization problems both multidisciplinary and single discipline feasibility schemes are considered. In all these cases a "convergence factor" is estimated in terms of the Jacobians and Hessians of the system, thus it can also be approximated by existing disciplinary analysis and optimization codes. The convergence factor is identified with the measure for the "coupling" between the disciplines in the system. Applications to algorithm development are discussed. Demonstration of the convergence estimates and numerical results are given for a system composed of two non-linear algebraic equations, and for a system composed of two PDEs modeling aeroelasticity.

  5. Suggesting a new European language policy.

    PubMed

    Nelde, Peter H

    2004-01-01

    Conflict is the most intriguing aspect of contact linguistics. Throughout history ever since the Tower of Babel was left unfinished, contacts between speakers of different languages have unavoidably resulted in conflicts between speakers of those languages. Without any doubt, the European Union (EU)--above all after the decision to enlarge the community--has accepted the multidisciplinary symbolic function of language and culture as a basis for European political unification. Accordingly, European Union policy makers have had to analyze conflicts caused by monolingualism and multilingualism, all aspects of contact linguistics. Can these conflicts be solved, minimized or neutralized by strategies of language planning, language policies and language politics? Initial results of European language policy strategies permit at least a cautious measure of optimism and open broad perspectives for the future of a New Multilingualism which will be discussed in our contribution. PMID:15156723

  6. Multidisciplinary teamwork in US primary health care.

    PubMed

    Solheim, Karen; McElmurry, Beverly J; Kim, Mi Ja

    2007-08-01

    Primary health care (PHC) is a systems perspective for examining the provision of essential health care for all. A multidisciplinary collaborative approach to health care delivery is associated with effective delivery and care providers' enrichment. Yet data regarding multidisciplinary practice within PHC are limited. The purpose of this exploratory qualitative descriptive study was to better understand team-based PHC practice in the US. Aims included (a) describing nursing faculty involvement in PHC, (b) analyzing ways that multidisciplinary work was enacted, and (c) recommending strategies for multidisciplinary PHC practice. After institutional review board (IRB) protocol approval, data collection occurred by: (a) surveying faculty/staff in a Midwestern nursing college (N=94) about their PHC practice, and (b) interviewing a purposive sample of nursing faculty/staff identified with PHC (n=10) and their health professional collaborators (n=10). Survey results (28% return rate) were summarized, interview notes were transcribed, and a systematic process of content analysis applied. Study findings show team practice is valued because health issues are complex, requiring different types of expertise; and because teams foster comprehensive care and improved resource use. Mission, membership attributes, and leadership influence teamwork. Though PHC is not a common term, nurses and their collaborators readily associated their practice with a PHC ethos. PHC practice requires understanding community complexity and engaging with community, family, and individual viewpoints. Though supports exist for PHC in the US, participants identified discord between their view of population needs and the health care system. The following interpretations arise from this study: PHC does not explicitly frame health care activity in the US, though some practitioners are committed to its ethics; and, teamwork within PHC is associated with better health care and rewarding professional

  7. [Multidisciplinary oncology teams: beware of endless discussions].

    PubMed

    Giard, Raimond W M

    2010-01-01

    The continual and increasing complexity of diagnostic and treatment options in oncology demands careful communication, coordination and decision making. Cancer care could be improved by multidisciplinary teamwork. Although this sort of teamwork has many advantages in theory, we know very little about its effectiveness in practice. We have to answer questions such as how teams can accomplish their task most effectively and how we must manage organizations in such a way that team-based working contributes optimally to organizational effectiveness. PMID:20619056

  8. Integrated multidisciplinary analysis tool IMAT users' guide

    NASA Technical Reports Server (NTRS)

    Meissner, Frances T. (Editor)

    1988-01-01

    The Integrated Multidisciplinary Analysis Tool (IMAT) is a computer software system developed at Langley Research Center. IMAT provides researchers and analysts with an efficient capability to analyze satellite controls systems influenced by structural dynamics. Using a menu-driven executive system, IMAT leads the user through the program options. IMAT links a relational database manager to commercial and in-house structural and controls analysis codes. This paper describes the IMAT software system and how to use it.

  9. European Community.

    PubMed

    1987-05-01

    The European Community was established in 1951 to reconcile France and Germany after World War II and to make possible the eventual federation of Europe. By 1986, there were 12 member countries: France, Italy, Belgium, the Federal Republic of Germany, Luxembourg, the Netherlands, Denmark, Ireland, the United Kingdom, Greece, Spain, and Portugal. Principal areas of concern are internal and external trade, agriculture, monetary coordination, fisheries, common industrial and commercial policies, assistance, science and research, and common social and regional policies. The European Community has a budget of US$34.035 billion/year, funded by customs duties and 1.4% of each member's value-added tax. The treaties establishing the European Community call for members to form a common market, a common customs tariff, and common agricultural, transport, economic, and nuclear policies. Major European Community institutions include the Commission, Council of Ministers, European Parliament, Court of Justice, and Economic and Social Committee. The Community is the world's largest trading unit, accounting for 15% of world trade. The 2 main goals of the Community's industrial policy are to create an open internal market and to promote technological innovation in order to improve international competitiveness. The European Community aims to contribute to the economic and social development of Third World countries as well. PMID:12177941

  10. Life prediction: A case for multidisciplinary research

    SciTech Connect

    Wei, R.P.

    1997-12-01

    Concerns with aging infrastructure worldwide and with the life-cycle costs and management of engineered systems have placed increased emphasis on the development of methods for life prediction. To be effective as true predictors of future performance (i.e., to provide accurate estimates beyond the range employed in the development of supporting data), such methods must be built upon mechanistic models that capture the functional dependence on all of the key external and internal variables. The development of these methods argues strongly for multidisciplinary research that integrates mechanistic understanding with probability analysis. In this paper, a mechanistically based probability approach to life prediction (versus the more traditional statistically based parametric approach) and the processes for model development are outlined to provide a framework for discussion. The use of a coordinated, multidisciplinary approach to develop mechanistic understanding and to model material response is illustrated through examples on crack growth in a high-strength steel. The need for multidisciplinary research that broadens the perspective from testing to testing and materials is discussed.

  11. Multidisciplinary tailoring of hot composite structures

    NASA Technical Reports Server (NTRS)

    Singhal, Surendra N.; Chamis, Christos C.

    1993-01-01

    A computational simulation procedure is described for multidisciplinary analysis and tailoring of layered multi-material hot composite engine structural components subjected to simultaneous multiple discipline-specific thermal, structural, vibration, and acoustic loads. The effect of aggressive environments is also simulated. The simulation is based on a three-dimensional finite element analysis technique in conjunction with structural mechanics codes, thermal/acoustic analysis methods, and tailoring procedures. The integrated multidisciplinary simulation procedure is general-purpose including the coupled effects of nonlinearities in structure geometry, material, loading, and environmental complexities. The composite material behavior is assessed at all composite scales, i.e., laminate/ply/constituents (fiber/matrix), via a nonlinear material characterization hygro-thermo-mechanical model. Sample tailoring cases exhibiting nonlinear material/loading/environmental behavior of aircraft engine fan blades, are presented. The various multidisciplinary loads lead to different tailored designs, even those competing with each other, as in the case of minimum material cost versus minimum structure weight and in the case of minimum vibration frequency versus minimum acoustic noise.

  12. Multidisciplinary tailoring of hot composite structures

    NASA Technical Reports Server (NTRS)

    Singhal, Surendra N.; Chamis, Christos C.

    1992-01-01

    A computational simulation procedure is described for multidisciplinary analysis and tailoring of multilayered multimaterial hot composite engine structural components subjected to simultaneous multiple discipline-specific thermal, structural, vibration, and acoustic loadings including the effect of aggressive environments. The simulation is based on a 3D finite element analysis technique in conjunction with structural mechanics codes, thermal/acoustic analysis methods, and tailoring procedures. The integrated multidisciplinary simulation procedure is general-purpose including the coupled effects of nonlinearities in structure geometry, material, loading, and environmental complexities. The composite material behavior is assessed at all composite scales, i.e., the laminate/ply/constituents (fiber/matrix), via a nonlinear material characterization hygro-thermomechanical model. Sample tailoring cases exhibiting nonlinear material/loading/environmental behavior of aircraft engine fan blades, are presented. The various multidisciplinary loadings lead to different tailored designs, even those opposite of each other, as in the case of minimum material cost versus minimum structure weight and in the case of minimum vibration frequency versus minimum acoustic noise.

  13. The European standards of Haemophilia Centres

    PubMed Central

    Giangrande, Paul; Calizzani, Gabriele; Menichini, Ivana; Candura, Fabio; Mannucci, Pier Mannuccio; Makris, Michael

    2014-01-01

    Introduction The European haemophilia community of professionals and patients has agreed on the principles of haemophilia care to address comprehensive optimal delivery of care which is nowadays scattered throughout Europe. Many of the health facilities call themselves Haemophilia Centres despite their variation in size, expertise and services provided. Only a small number of countries have Haemophilia Centre accreditation systems in place. Methods In the framework of the European Haemophilia Network project, following an inclusive process of stakeholder involvement, the European Guidelines for the certification of haemophilia centres have been developed in order to set quality standards for European Haemophilia Centres and criteria for their certification. Results The Guidelines define the standards and criteria for the designation of two levels of care delivery: European Haemophilia Treatment Centres, providing local routine care, and European Haemophilia Comprehensive Care Centres, providing specialised and multi-disciplinary care and functioning as tertiary referral centres. Additionally, they define standards about general requirements, patient care, provision of an advisory service and establishment of network of clinical and specialised services. Conclusions The implementation of the European Guidelines for the certification of Haemophilia Centres will contribute to the reduction of health inequalities through the standardisation of quality of care in European Union Member States and could represent a model to be taken into consideration for other rare disease groups. PMID:24922293

  14. European Master's Program in Gerontology (EuMaG): Goals, Curriculum, and Students

    ERIC Educational Resources Information Center

    Aartsen, Marja

    2011-01-01

    The European Master's Program in Gerontology (EuMaG) started in September 2003 with support from the European Commission. The EuMaG is a modular, 2-year, part-time international training program about the aging process and its societal implications. The multidisciplinary curriculum comprises four domains of gerontology (i.e., social gerontology,…

  15. Multidisciplinary task force for controlling drug expenses.

    PubMed

    Hayman, J N; Crane, V S

    1993-11-01

    The establishment of a multidisciplinary task force to control increasing drug costs is described. From 1986 to 1992, dollars spent on drugs at a 964-bed teaching hospital increased from $9.8 million to $26.8 million, despite a tightly controlled formulary, prudent purchasing practices, prescribing restrictions, an antimicrobial order form program, a target-drug program, and an active pharmacy-run cost intervention program. These increases occurred as a result of changes in the mix of drugs prescribed, increases in outpatient volume, inflation, and price increases resulting from the Omnibus Budget Reconciliation Act of 1990. A multidisciplinary task force composed of seven teams--AIDS and related issues, ambulatory care, medicine, obstetrics and gynecology, pediatrics, surgery, and systems and procedures--was formed to identify ways to reduce drug expenses and enhance revenue. Each team made recommendations designed to reduce the rate of growth of pharmaceutical expenses. To implement these recommendations, the task force used a variety of verbal and written strategies to educate and communicate with physicians, pharmacists, nurses, pharmaceutical company representatives, and patients. A system was developed so that goal achievement could be monitored. The program, which was implemented on September 16, 1991, and continued through September 30, 1992, reduced the growth in drug expense by $2.33 million. As a result of the program, control of the drug expenses became an institutional priority, not merely a pharmacy department priority. By establishing a multidisciplinary team approach involving physicians, administrators, nurses, and pharmacists, a substantial reduction in the growth of drug expenses can be achieved. PMID:8266959

  16. Multidisciplinary perspectives on banana (Musa spp.) domestication

    PubMed Central

    Perrier, Xavier; De Langhe, Edmond; Donohue, Mark; Lentfer, Carol; Vrydaghs, Luc; Bakry, Frédéric; Carreel, Françoise; Hippolyte, Isabelle; Horry, Jean-Pierre; Jenny, Christophe; Lebot, Vincent; Risterucci, Ange-Marie; Tomekpe, Kodjo; Doutrelepont, Hugues; Ball, Terry; Manwaring, Jason; de Maret, Pierre; Denham, Tim

    2011-01-01

    Original multidisciplinary research hereby clarifies the complex geodomestication pathways that generated the vast range of banana cultivars (cvs). Genetic analyses identify the wild ancestors of modern-day cvs and elucidate several key stages of domestication for different cv groups. Archaeology and linguistics shed light on the historical roles of people in the movement and cultivation of bananas from New Guinea to West Africa during the Holocene. The historical reconstruction of domestication processes is essential for breeding programs seeking to diversify and improve banana cvs for the future. PMID:21730145

  17. Multidisciplinary Techniques and Novel Aircraft Control Systems

    NASA Technical Reports Server (NTRS)

    Padula, Sharon L.; Rogers, James L.; Raney, David L.

    2000-01-01

    The Aircraft Morphing Program at NASA Langley Research Center explores opportunities to improve airframe designs with smart technologies. Two elements of this basic research program are multidisciplinary design optimization (MDO) and advanced flow control. This paper describes examples where MDO techniques such as sensitivity analysis, automatic differentiation, and genetic algorithms contribute to the design of novel control systems. In the test case, the design and use of distributed shapechange devices to provide low-rate maneuvering capability for a tailless aircraft is considered. The ability of MDO to add value to control system development is illustrated using results from several years of research funded by the Aircraft Morphing Program.

  18. Multidisciplinary Design Of Hot Composite Structures

    NASA Technical Reports Server (NTRS)

    Chamis, Christos C.; Singhal, Surendra N.

    1996-01-01

    Unified computer code developed to implement multidisciplinary approach to design and analysis of composite-material structures that must withstand high temperatures. Code modular: includes executive module communicating with and coordinating other modules performing calculations pertaining to traditionally separate disciplines like those of acoustics, structural vibrations, structural loads, and thermal effects. Essential feature, finite-element numerical simulation of relevant physical phenomena according to applicable disciplines. Same finite-element mesh used in thermal, vibrational, and structural analyses; minimizing data-preparation time and eliminating errors incurred in transforming temperatures from one finite-element mesh to another.

  19. Multidisciplinary Techniques and Novel Aircraft Control Systems

    NASA Technical Reports Server (NTRS)

    Padula, Sharon L.; Rogers, James L.; Raney, David L.

    2000-01-01

    The Aircraft Morphing Program at NASA Langley Research Center explores opportunities to improve airframe designs with smart technologies. Two elements of this basic research program are multidisciplinary design optimization (MDO) and advanced flow control. This paper describes examples where MDO techniques such as sensitivity analysis, automatic differentiation, and genetic algorithms contribute to the design of novel control systems. In the test case, the design and use of distributed shape-change devices to provide low-rate maneuvering capability for a tailless aircraft is considered. The ability of MDO to add value to control system development is illustrated using results from several years of research funded by the Aircraft Morphing Program.

  20. Multidisciplinary meetings as an effective clinical intervention.

    PubMed

    MacCallam, Jackie; Higgins, Lisa

    2014-06-01

    When used well, multidisciplinary meetings can function in the same way as other clinical interventions to improve communication, efficiency and outcomes. They help break down barriers, manage difficult emotions, and benefit service users and staff. But it is imperative that they are well prepared, well attended, and that the purpose and agenda are agreed. It is also vital to have an efficient chair and that meetings take place in an environment where feelings can be shared openly and respected. Services should recognise and address relevant training and support requirements. PMID:24914667

  1. Multi-Disciplinary Analysis and Optimization Frameworks

    NASA Technical Reports Server (NTRS)

    Naiman, Cynthia Gutierrez

    2009-01-01

    Since July 2008, the Multidisciplinary Analysis & Optimization Working Group (MDAO WG) of the Systems Analysis Design & Optimization (SAD&O) discipline in the Fundamental Aeronautics Program s Subsonic Fixed Wing (SFW) project completed one major milestone, Define Architecture & Interfaces for Next Generation Open Source MDAO Framework Milestone (9/30/08), and is completing the Generation 1 Framework validation milestone, which is due December 2008. Included in the presentation are: details of progress on developing the Open MDAO framework, modeling and testing the Generation 1 Framework, progress toward establishing partnerships with external parties, and discussion of additional potential collaborations

  2. Multidisciplinary perspectives on banana (Musa spp.) domestication.

    PubMed

    Perrier, Xavier; De Langhe, Edmond; Donohue, Mark; Lentfer, Carol; Vrydaghs, Luc; Bakry, Frédéric; Carreel, Françoise; Hippolyte, Isabelle; Horry, Jean-Pierre; Jenny, Christophe; Lebot, Vincent; Risterucci, Ange-Marie; Tomekpe, Kodjo; Doutrelepont, Hugues; Ball, Terry; Manwaring, Jason; de Maret, Pierre; Denham, Tim

    2011-07-12

    Original multidisciplinary research hereby clarifies the complex geodomestication pathways that generated the vast range of banana cultivars (cvs). Genetic analyses identify the wild ancestors of modern-day cvs and elucidate several key stages of domestication for different cv groups. Archaeology and linguistics shed light on the historical roles of people in the movement and cultivation of bananas from New Guinea to West Africa during the Holocene. The historical reconstruction of domestication processes is essential for breeding programs seeking to diversify and improve banana cvs for the future. PMID:21730145

  3. Multidisciplinary intensive care in extensive necrotizing fasciitis.

    PubMed

    Tu, Guo-Wei; Hwabejire, J O; Ju, Min-Jie; Yang, Yuan-Feng; Zhang, Guang-Jian; Xu, Jian-Wei; Xue, Zhang-Gang; Jiang, Chun; Jiang, C; Luo, Zhe; Luo, Z

    2013-04-01

    This is a case report of extensive necrotizing fasciitis (NF). A 65-year-old man presented with high fever, pain, swelling, and redness of the perineum, scrotum, and right lower limb. Based on the clinical symptoms and an imaging examination, a diagnosis of NF was made. The patient underwent an extensive exploration followed by daily bedside debridement. A diversion colostomy and six additional debridement procedures on the right thigh and perineum were subsequently performed. Although the patient had an eventful course, he recovered well under a multidisciplinary treatment regimen. The treatment and hospital course of the patient are described. PMID:23104255

  4. Integrated multidisciplinary analysis of segmented reflector telescopes

    NASA Technical Reports Server (NTRS)

    Briggs, Hugh C.; Needels, Laura

    1992-01-01

    The present multidisciplinary telescope-analysis approach, which encompasses thermal, structural, control and optical considerations, is illustrated for the case of an IR telescope in LEO; attention is given to end-to-end evaluations of the effects of mechanical disturbances and thermal gradients in measures of optical performance. Both geometric ray-tracing and surface-to-surface diffraction approximations are used in the telescope's optical model. Also noted is the role played by NASA-JPL's Integrated Modeling of Advanced Optical Systems computation tool, in view of numerical samples.

  5. Multidisciplinary Graduate Education in Bioprocess Engineering

    SciTech Connect

    Mark A. Eiteman

    2006-04-18

    This report describes the accomplishments of the University of Georgia in establishing an academic program geared toward the emerging biobased products industry. By virtue of its strengths and structure, the University of Georgia is particularly well-suited for developing a program focused on plant- and microbial-based bioproducts, and it was in this general area that this program was developed. The program had several unique characteristics. First, we implemented a distinguished lecture series that brought outstanding scientists and engineers to our University to interact with students and share their vision of the biobased economy. Second, we offered industrially-oriented and multidisciplinary courses that provided students with a broad background on various facets of biobased business and technology. Third, we provided the students with opportunities to expand beyond the classroom by engaging in research lab rotations and industrial internships. Fourth, each student was engaged in a creative research project as led by a multidisciplinary faculty team. Throughout the implementation of these activities, we maintained a student-centered, mentoring approach to education. The most tangible outcome of this project was the graduation of two students who participated in a variety of scholarly activities, culminating in research toward the completion of a thesis and dissertation. Both research projects involved the use of microorganisms to produce industrial products from agricultural substrates via fermentation processes. The research advanced our understanding of microorganisms as used for industrial processes and products, as described in several articles published in scholarly journals and presentations made at scientific conferences (see information on pp. 14-15). Another outcome is one graduate course, Fermentation Engineering Laboratory, which is a unique experiential and multidisciplinary course. This course will be offered in the future as an elective to

  6. Dynamically Reconfigurable Approach to Multidisciplinary Problems

    NASA Technical Reports Server (NTRS)

    Alexandrov, Natalie M.; Lewis, Robert Michael

    2003-01-01

    The complexity and autonomy of the constituent disciplines and the diversity of the disciplinary data formats make the task of integrating simulations into a multidisciplinary design optimization problem extremely time-consuming and difficult. We propose a dynamically reconfigurable approach to MDO problem formulation wherein an appropriate implementation of the disciplinary information results in basic computational components that can be combined into different MDO problem formulations and solution algorithms, including hybrid strategies, with relative ease. The ability to re-use the computational components is due to the special structure of the MDO problem. We believe that this structure can and should be used to formulate and solve optimization problems in the multidisciplinary context. The present work identifies the basic computational components in several MDO problem formulations and examines the dynamically reconfigurable approach in the context of a popular class of optimization methods. We show that if the disciplinary sensitivity information is implemented in a modular fashion, the transfer of sensitivity information among the formulations under study is straightforward. This enables not only experimentation with a variety of problem formations in a research environment, but also the flexible use of formulations in a production design environment.

  7. A multidisciplinary approach for improving outcomes.

    PubMed

    Sierchio, Grace P

    2003-01-01

    The healthcare environment has been impacted tremendously by higher patient acuity, cost-cutting measures, an increase in litigation, and increased expectations by an educated generation of healthcare consumers. This has led to the need to continually measure, assess, and improve quality. These activities must consider not only patient clinical outcomes, but also customer service ratings and financial outcomes. Quality improvement requires a collaborative approach to succeed, and the need to build a cohesive and effective multidisciplinary team is critical for positive outcomes. Strategies to build a culture of teamwork include incorporating total quality management principles into every level of the organization, seeking participation from every discipline and level of the organization, and recognizing employees for their efforts. Infusion nurses have an excellent opportunity to contribute their expertise to any multidisciplinary team that impacts the outcomes of infusion patients. In addition, team-building and quality improvement may prove to be excellent career moves for infusion nurses looking to further specialize their practice. PMID:12544365

  8. A Multidisciplinary Approach to Improving SCIP Compliance.

    PubMed

    Huntington, Ciara R; Strayer, Melissa; Huynh, Toan; Green, John M

    2015-07-01

    The Surgical Care Improvement Project (SCIP) is a national program aimed at reducing perioperative complications and is a quality benchmark metric for Centers for Medicare and Medicaid Services. This study evaluates whether a multidisciplinary program improved an institution's compliance with SCIP measures. Analysis of the facility's performance data identified three key areas of SCIP noncompliance: 1) timely discontinuation of perioperative antibiotics and urinary catheters, 2) initiation of venous thromboembolism prophylaxis, and 3) perioperative beta blocker administration. Multidisciplinary teams collaborated with providers and department chairs in reviewing and enable SCIP compliance. Anesthesia staff managed preoperative antibiotics. SCIP-compliant order sets, venous thromboembolism pop-up alerts, and progress note templates were added to the electronic medical record. Standardized education was provided to explain SCIP requirements, review noncompliant cases, and update teams on SCIP performance. Data were captured from January 2009 to March 2014. Ten SCIP fallouts were reported for general surgery specialties in January 2013, when the SCIP compliance project launched. Specifically, colon-related surgery achieved 100 per cent compliance. Six months after implementation, overall SCIP compliance at our institution improved by 65 per cent (from 90.7-98.6% compliance). PMID:26140888

  9. Multidisciplinary design optimization using multiobjective formulation techniques

    NASA Technical Reports Server (NTRS)

    Chattopadhyay, Aditi; Pagaldipti, Narayanan S.

    1995-01-01

    This report addresses the development of a multidisciplinary optimization procedure using an efficient semi-analytical sensitivity analysis technique and multilevel decomposition for the design of aerospace vehicles. A semi-analytical sensitivity analysis procedure is developed for calculating computational grid sensitivities and aerodynamic design sensitivities. Accuracy and efficiency of the sensitivity analysis procedure is established through comparison of the results with those obtained using a finite difference technique. The developed sensitivity analysis technique are then used within a multidisciplinary optimization procedure for designing aerospace vehicles. The optimization problem, with the integration of aerodynamics and structures, is decomposed into two levels. Optimization is performed for improved aerodynamic performance at the first level and improved structural performance at the second level. Aerodynamic analysis is performed by solving the three-dimensional parabolized Navier Stokes equations. A nonlinear programming technique and an approximate analysis procedure are used for optimization. The proceduredeveloped is applied to design the wing of a high speed aircraft. Results obtained show significant improvements in the aircraft aerodynamic and structural performance when compared to a reference or baseline configuration. The use of the semi-analytical sensitivity technique provides significant computational savings.

  10. Multidisciplinary approaches to the pressure ulcer problem.

    PubMed

    Bogie, Kath M; Ho, Chester H

    2007-10-01

    Multiple factors affect the specific condition and overall clinical profile of individuals at risk for chronic wounds. The complexity of the pressure ulcer problem lends itself to the application of the National Institute of Health Roadmap Initiative that encourages interdisciplinary research and new organizational models. An overview of research studies relevant to telemedicine and neuromuscular electrical stimulation in the care and prevention of pressure ulcers as well as preliminary results of an innovative multidisciplinary skin care team approach to the primary and tertiary prevention of pressure ulcers are encouraging. The team's pilot study results indicate that patients are satisfied with telehealth provision of care; however, literature and experience also suggest that discrepancies in the inter-rater assessment of wounds using digital photography remain, particularly with regard to wound dimension variables assessed (P<0.01). In another endeavor, the skin care team developed a Longitudinal Analysis with Self-Registration statistical algorithm to assess the effects of electrical stimulation; in a preliminary study, this tool documented improvement in gluteus maximus health and resultant ability to withstand pressure. As the number of groups pursuing multidisciplinary research and care increases, so, too, will the evidence base required to address these common, and complex, chronic wounds. PMID:17978412

  11. Panel Discussion on Multi-Disciplinary Analysis

    NASA Technical Reports Server (NTRS)

    Garcia, Robert

    2002-01-01

    The Marshall Space Flight Center (MSFC) is hosting the Thermal and Fluids Analysis Workshop (TFAWS) during the week of September 10, 2001. Included in this year's TFAWS is a panel session on Multidisciplinary Analysis techniques. The intent is to provide an opportunity for the users to gain information as to what product may be best suited for their applications environment and to provide feedback to you, the developers, on future desired developments. Potential users of multidisciplinary analysis (MDA) techniques are often overwhelmed by the number of choices available to them via commercial products and by the pace of new developments in this area. The purpose of this panel session is to provide a forum wherein MDA tools available and under development can be discussed, compared, and contrasted. The intent of this panel is to provide the end-user with the information necessary to make educated decisions on how to proceed with selecting their MDA tool. It is anticipated that the discussions this year will focus on MDA techniques that couple discipline codes or algorithms (as opposed to monolithic, unified MDA approaches). The MDA developers will be asked to prepare a product overview presentation addressing specific questions provided by the panel organizers. The purpose of these questions will be to establish the method employed by the particular MDA technique for communication between the discipline codes, to establish the similarities and differences amongst the various approaches, and to establish the range of experience and applications for each particular MDA approach.

  12. Information Management for a Large Multidisciplinary Project

    NASA Technical Reports Server (NTRS)

    Jones, Kennie H.; Randall, Donald P.; Cronin, Catherine K.

    1992-01-01

    In 1989, NASA's Langley Research Center (LaRC) initiated the High-Speed Airframe Integration Research (HiSAIR) Program to develop and demonstrate an integrated environment for high-speed aircraft design using advanced multidisciplinary analysis and optimization procedures. The major goals of this program were to evolve the interactions among disciplines and promote sharing of information, to provide a timely exchange of information among aeronautical disciplines, and to increase the awareness of the effects each discipline has upon other disciplines. LaRC historically has emphasized the advancement of analysis techniques. HiSAIR was founded to synthesize these advanced methods into a multidisciplinary design process emphasizing information feedback among disciplines and optimization. Crucial to the development of such an environment are the definition of the required data exchanges and the methodology for both recording the information and providing the exchanges in a timely manner. These requirements demand extensive use of data management techniques, graphic visualization, and interactive computing. HiSAIR represents the first attempt at LaRC to promote interdisciplinary information exchange on a large scale using advanced data management methodologies combined with state-of-the-art, scientific visualization techniques on graphics workstations in a distributed computing environment. The subject of this paper is the development of the data management system for HiSAIR.

  13. Opus: A Coordination Language for Multidisciplinary Applications

    NASA Technical Reports Server (NTRS)

    Chapman, Barbara; Haines, Matthew; Mehrotra, Piyush; Zima, Hans; vanRosendale, John

    1997-01-01

    Data parallel languages, such as High Performance fortran, can be successfully applied to a wide range of numerical applications. However, many advanced scientific and engineering applications are multidisciplinary and heterogeneous in nature, and thus do not fit well into the data parallel paradigm. In this paper we present Opus, a language designed to fill this gap. The central concept of Opus is a mechanism called ShareD Abstractions (SDA). An SDA can be used as a computation server, i.e., a locus of computational activity, or as a data repository for sharing data between asynchronous tasks. SDAs can be internally data parallel, providing support for the integration of data and task parallelism as well as nested task parallelism. They can thus be used to express multidisciplinary applications in a natural and efficient way. In this paper we describe the features of the language through a series of examples and give an overview of the runtime support required to implement these concepts in parallel and distributed environments.

  14. Integrated brokering framework for multi-disciplinary research

    NASA Astrophysics Data System (ADS)

    Craglia, M.; Vaccari, L.; Santoro, M.; Nativi, S.

    2012-04-01

    EuroGEOSS is a research project supporting the development of the GEOSS Common Infrastructure and the multi-disciplinary research efforts needed to address global sustainability research. The framework it has developed to integrate data, services, and models from different disciplines is based on a brokering approach that advances the traditional Service Oriented Architecture of spatial data infrastructures. In this paper we demonstrate the added value of this approach. The scientific question we address in this example is o identify ecosystems similar to the ones found in the protected area of "Sierra De Queixa Montes De Invernadeiro Nature Park" in Galicia, Spain. To do this, the user would identify an analytical model suitable to address the question such as the eHabitat model developed by the European Commission Joint Research Centre. It would then use the EuroGEOSS broker to look for the data necessary to run the model such boundaries of the select park, mean drought index, %forest cover, temperature and rainfall, and elevation. The eHabitat model is used to compute the likelihood to find ecosystems in the selected window that are similar to the one found in the selected protected area. The end-user would therefore run the model directly on the web as a web processing service with the data identified in the broker (no need to download the data) and use this information to draw a new area to be protected that would have similar ecological conditions to the initial protected area and display the list of endangered species (to be defined) expected to be found in the new location. Finally, the user can also mine Web 2.0 social networks via the broker to identify pictures of the selected species in the area of interest. This integrated approach based on open standards and interfaces allows the user to find, access, and use the data and models in a transparent way focusing on the research questions to be addressed rather than the technology that delivers the inputs

  15. Multidisciplinary approach in natural hazards: avoiding misunderstandings

    NASA Astrophysics Data System (ADS)

    Angignard, M.

    2009-04-01

    It is today widely recognised that a multidisciplinary approach is worthwhile when it comes to natural hazards. While the knowledge of scientists from different fields about those problematic is getting deeper everyday, the need for a brighter understanding of natural hazards and the risk they induce becomes more and more obvious. A risk situation cannot be limited to a single scientific field. It involves many components, each of them studied by a specific science. The understanding of the whole question of risk requires a dialogue between those sciences. The large amount of research projects based on a multidisciplinary approach shows that this need for dialogue is known and accepted. However, the participants of such projects encounter a problem in communication: they do not speak the same language. Even though scientists are willing to share with colleagues from other fields, they are facing the hinder of the specific terminology they use in their work. Social scientists, natural scientists and engineering scientists do not speak the same language, although they might use the same words. For instance, basic terms like "risk", "vulnerability", or concepts like "risk management" or "governance" might have very different meanings according to the scientists involved. The approach of risk situation itself is specific to each science. How can this hindrance be avoided? The first step of every research project (and further, every work in group on a risk related situation) could be a framing about terminology. It is necessary that all partners acknowledge the different vocabularies involved, and understand that their background and professional context influences their understanding of terms and concepts. The aim is not to negate those vocabularies, nor to define a new one that would fit to all sciences. It is to ensure that all partners are aware of the possible misunderstandings and accept that others might use other terminologies. Thus, major misunderstandings

  16. [Low back pain during pregnancy. Multidisciplinary approach].

    PubMed

    Gallo-Padilla, D; Gallo-Padilla, C; Gallo-Vallejo, F J; Gallo-Vallejo, J L

    2016-09-01

    After explaining that low back pain is considered the most common pregnancy complication, its pathogenesis, risk factors and the clinical characteristics of the very painful symptoms of this condition are described. As for its approach, it is stressed that it must be multidisciplinary, introducing very important preventive measures, including proper postural hygiene. For its treatment, the methods may be based on non-surgical or pharmacological interventions of a conservative non-invasive nature. Thus, physiotherapy, osteopathic manipulation, multimodal intervention (exercise and education), exercises performed in water environment, acupuncture, etc., have proven to be effective. Finally, it is emphasised that given the significant impact on their quality of life, different health professionals must be proactive and treat the lumbar disease in pregnant women. PMID:26239672

  17. NASA Multidisciplinary Design and Analysis Fellowship Program

    NASA Technical Reports Server (NTRS)

    1995-01-01

    This report is a Year 1 interim report of the progress on the NASA multidisciplinary Design and Analysis Fellowship Program covering the period, January 1, 1995 through September 30, 1995. It summarizes progress in establishing the MDA Fellowship Program at Georgia Tech during the initial year. Progress in the advertisement of the program, recruiting results for the 1995-96 academic year, placement of the Fellows in industry during Summer 1995, program development at the M.S. and Ph.D. levels, and collaboration and dissemination of results are summarized in this report. Further details of the first year's progress will be included in the report from the Year 1 Workshop to be held at NASA Langley on December 7-8, 1995.

  18. Multidisciplinary Interventions in Motor Neuron Disease

    PubMed Central

    Williams, U. E.; Philip-Ephraim, E. E.; Oparah, S. K.

    2014-01-01

    Motor neuron disease is a neurodegenerative disease characterized by loss of upper motor neuron in the motor cortex and lower motor neurons in the brain stem and spinal cord. Death occurs 2–4 years after the onset of the disease. A complex interplay of cellular processes such as mitochondrial dysfunction, oxidative stress, excitotoxicity, and impaired axonal transport are proposed pathogenetic processes underlying neuronal cell loss. Currently evidence exists for the use of riluzole as a disease modifying drug; multidisciplinary team care approach to patient management; noninvasive ventilation for respiratory management; botulinum toxin B for sialorrhoea treatment; palliative care throughout the course of the disease; and Modafinil use for fatigue treatment. Further research is needed in management of dysphagia, bronchial secretion, pseudobulbar affect, spasticity, cramps, insomnia, cognitive impairment, and communication in motor neuron disease. PMID:26317009

  19. Pemphigus vulgaris: a multidisciplinary approach to management.

    PubMed

    Vinall, Christopher; Stevens, Lucy; McArdle, Paul

    2013-01-01

    Pemphigus vulgaris (PV) is a rare but potentially life-threatening autoimmune disease affecting the mucosa and the skin. The disease is caused by circulating antibodies to desmosomes (important adhesion proteins linking cells together). Disruption of these intercellular connections results in a loss of cohesion between cells (acantholysis). The clinical result of this process is the development of multiple blisters that easily rupture, leaving behind painful sloughing eroded areas of mucosa and/or skin. We report a case of severe PV in a 56-year-old man presenting with widespread, painful, eroded mucocutaneous lesions. The severity of the disease demanded a range of medical and surgical specialties to successfully manage the problem. This paper highlights the importance of an early multidisciplinary team approach to improve the outcome of patients suffering with this disease. PMID:24343801

  20. Teamwork: a multidisciplinary pediatric-liaison service.

    PubMed

    Froese, A P; Kamin, L E; Levine, C A

    Psychiatrists, psychologists and social workers are often consulted about the same hospitalized patient. Since each may differ in their training, orientation and experience, the opinions expressed by them to the consultee may differ. The authors have described a multidisciplinary liaison team operating within a pediatric teaching hospital. The consultants work as a team in close collaboration with each other and with the psychiatric nurse clinician and an occupational therapist. The team approach has specific advantages. It allows for a concise and unified approach to the emotional and social needs of the patients. It presents a forum for informal consultations and interdisciplinary meetings. In addition, teaching opportunities are many as each discipline learns from the other. PMID:1052083

  1. Directions in environmental gerontology: a multidisciplinary field.

    PubMed

    Kendig, Hal

    2003-10-01

    This article considers developments and directions for environmental gerontology drawing on the three papers in this Forum. The multidisciplinary field came of age during the 1960s with Powell Lawton's powerful environmental press paradigm and its applications to empirical research and building design. Recent theoretical developments in Europe and America have advanced and integrated concepts in psychology, geography, and related disciplines. Time dimensions and active use of space are essential for understanding aging individuals and microenvironments as well as changing populations and macroenvironments. Research on residential environments by health professions is informing community care that is enhancing the independence and well-being of older people. With its proven responsiveness to social and policy priorities, environmental gerontology is now providing strong conceptual and empirical bases for advancing healthy aging and age-friendly societies. PMID:14570957

  2. Multidisciplinary systems optimization by linear decomposition

    NASA Technical Reports Server (NTRS)

    Sobieski, J.

    1984-01-01

    In a typical design process major decisions are made sequentially. An illustrated example is given for an aircraft design in which the aerodynamic shape is usually decided first, then the airframe is sized for strength and so forth. An analogous sequence could be laid out for any other major industrial product, for instance, a ship. The loops in the discipline boxes symbolize iterative design improvements carried out within the confines of a single engineering discipline, or subsystem. The loops spanning several boxes depict multidisciplinary design improvement iterations. Omitted for graphical simplicity is parallelism of the disciplinary subtasks. The parallelism is important in order to develop a broad workfront necessary to shorten the design time. If all the intradisciplinary and interdisciplinary iterations were carried out to convergence, the process could yield a numerically optimal design. However, it usually stops short of that because of time and money limitations. This is especially true for the interdisciplinary iterations.

  3. NASA Multidisciplinary Design and Analysis Fellowship Program

    NASA Technical Reports Server (NTRS)

    Schrage, D. P.; Craig, J. I.; Mavris, D. N.; Hale, M. A.; DeLaurentis, D.

    1999-01-01

    This report summarizes the results of a multi-year training grant for the development and implementation of a Multidisciplinary Design and Analysis (MDA) Fellowship Program at Georgia Tech. The Program funded the creation of graduate MS and PhD degree programs in aerospace systems design, analysis and integration. It also provided prestigious Fellowships with associated Industry Internships for outstanding engineering students. The graduate program has become the foundation for a vigorous and productive research effort and has produced: 20 MS degrees, 7 Ph.D. degrees, and has contributed to 9 ongoing Ph.D. students. The results of the research are documented in 32 publications (23 of which are included on a companion CDROM) and 4 annual student design reports (included on a companion CDROM). The legacy of this critical funding is the Center for Aerospace Systems Analysis at Georgia Tech which is continuing the graduate program, the research, and the industry internships established by this grant.

  4. Multidisciplinary clinical management of paroxysmal nocturnal hemoglobinuria

    PubMed Central

    Sahin, Fahri; Ozkan, Melda Comert; Mete, Nihal Gokmen; Yilmaz, Mumtaz; Oruc, Nevin; Gurgun, Alev; Kayikcioglu, Meral; Guler, Ayse; Gokcay, Figen; Bilgir, Ferda; Ceylan, Cengiz; Bilgir, Oktay; Sari, Ismail Hakan; Saydam, Guray

    2015-01-01

    Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired disease caused by clonal expansion of one or more hematopoietic stem cell (HSC) lines due to a somatic mutation of the phosphatidylinositol glycan anchor (PIG-A) gene located on Xp22.1. PNH incidence is 1.5-2 cases per million of the population per year. PNH can affect multiple systems in the body and requires multidisciplinary clinical management. Patients can manifest with severe pancytopenia, life-threatening thrombosis affecting the hepatic, abdominal, cerebral, and subdermal veins, and high requirements for blood transfusion due to haemolytic anemia. PNH can also be associated with bone marrow failure. Advances in diagnostic techniques and a targeted therapeutic approach for PNH have emerged in the last two decades. Eculizumab, a promising humanized monoclonal antibody against C5, is the first approved therapy for PNH. PMID:26171279

  5. A Unified Approach to Modeling Multidisciplinary Interactions

    NASA Technical Reports Server (NTRS)

    Samareh, Jamshid A.; Bhatia, Kumar G.

    2000-01-01

    There are a number of existing methods to transfer information among various disciplines. For a multidisciplinary application with n disciplines, the traditional methods may be required to model (n(exp 2) - n) interactions. This paper presents a unified three-dimensional approach that reduces the number of interactions from (n(exp 2) - n) to 2n by using a computer-aided design model. The proposed modeling approach unifies the interactions among various disciplines. The approach is independent of specific discipline implementation, and a number of existing methods can be reformulated in the context of the proposed unified approach. This paper provides an overview of the proposed unified approach and reformulations for two existing methods. The unified approach is specially tailored for application environments where the geometry is created and managed through a computer-aided design system. Results are presented for a blended-wing body and a high-speed civil transport.

  6. GeoEnvironmental Education Through Multidisciplinary Research

    NASA Astrophysics Data System (ADS)

    Padilla, I. Y.; Hwang, S.

    2007-12-01

    The growing need to understand environmental and geological processes, their impacts, and solutions in a dynamic world requires a diverse, multidiscipline, and multicultural approach in science and engineering. In the last few years, faculty at the University of Puerto Rico, Mayagüez have engaged in education and training activities aimed at developing a critical mass of students that can address a wide range of geoenvironmental problems through multidisciplinary research. Students of diverse age, gender, culture, and academic disciplines addressing different research questions work together in a common space. Hierarchy assignments use senior students as primary mentors, but foster work at parallel levels that require sharing and developing knowledge and research resources. The activities have resulted in a significant increase in the number of diverse students in science and engineering areas related to the environment.

  7. A multidisciplinary conceptualization of conservation opportunity.

    PubMed

    Moon, Katie; Adams, Vanessa M; Januchowski-Hartley, Stephanie R; Polyakov, Maksym; Mills, Morena; Biggs, Duan; Knight, Andrew T; Game, Edward T; Raymond, Christopher M

    2014-12-01

    An opportunity represents an advantageous combination of circumstances that allows goals to be achieved. We reviewed the nature of opportunity and how it manifests in different subsystems (e.g., biophysical, social, political, economic) as conceptualized in other bodies of literature, including behavior, adoption, entrepreneur, public policy, and resilience literature. We then developed a multidisciplinary conceptualization of conservation opportunity. We identified 3 types of conservation opportunity: potential, actors remove barriers to problem solving by identifying the capabilities within the system that can be manipulated to create support for conservation action; traction, actors identify windows of opportunity that arise from exogenous shocks, events, or changes that remove barriers to solving problems; and existing, everything is in place for conservation action (i.e., no barriers exist) and an actor takes advantage of the existing circumstances to solve problems. Different leverage points characterize each type of opportunity. Thus, unique stages of opportunity identification or creation and exploitation exist: characterizing the system and defining problems; identifying potential solutions; assessing the feasibility of solutions; identifying or creating opportunities; and taking advantage of opportunities. These stages can be undertaken independently or as part of a situational analysis and typically comprise the first stage, but they can also be conducted iteratively throughout a conservation planning process. Four types of entrepreneur can be identified (business, policy, social, and conservation), each possessing attributes that enable them to identify or create opportunities and take advantage of them. We examined how different types of conservation opportunity manifest in a social-ecological system (the Great Barrier Reef) and how they can be taken advantage of. Our multidisciplinary conceptualization of conservation opportunity strengthens and

  8. [Irritable Bowel Syndrome treatment: a multidisciplinary approach].

    PubMed

    Shani-Zur, Dana; Wolkomir, Keren

    2015-01-01

    Irritable Bowel Syndrome affects 9-23% of the general population. This diagnosis contributes to more frequent doctor visits and multiple consultations by patients. The current approach to treating IBS is symptomatic and consists of a regimen of first line pharmacological treatment options; the use of anti-depressant drugs is also common. The efficiency of complementary medicine in the treatment of IBS has been studied in the last few years. Qualitative multidisciplinary approach studies, using personalized medicines with complementary therapies are needed. We present the case of a 39-year-old woman with a diagnosis of IBS since 2009, who complained about gastrointestinal symptoms since the age of 13 and severe episodes of spasmodic stomach aches in the last year self-ranked as 10, on a 0-10 scale; 3-4 episodes a month, which last for 5 days, accompanied by severe flatulence and bloating. In addition, she has constipation (one bowel movement every 10 days), alternating with multiple diarrheic bowel movements (6 times a day). Using a multidisciplinary approach, including medicinal care, Chinese medicine, reflexology and naturopathy resulted in significant improvement in symptoms and quality of life, as well as gradual reduction of drugs, approved by her physician. Stomach ache self-ranked now as 1, on a 0-10 scale; and flatulence and bloating self-ranked as mild. Bowel movement frequency increased and is now every other day. She no longer has diarrheic and/or multiple bowel movements. This case report emphasizes the importance of integrative treatment in IBS and its benefit in improving patients' quality of life. PMID:25796677

  9. GEOWOW: a drought scenario for multidisciplinary data access and use

    NASA Astrophysics Data System (ADS)

    Santoro, Mattia; Sorichetta, Alessandro; Roglia, Elena; Craglia, Massimo; Nativi, Stefano

    2013-04-01

    Recent enhancements of the GEOSS Common Infrastructure (GCI; http://www.earthobservations.org/gci_gci.shtml), and in particular the introduction of a middleware in the GCI that brokers across heterogeneous information systems, have increased significantly the number of information resources discoverable worldwide. Now the challenge moves to the next level of ensuring access and use of the resources discovered, which have many different and domain-specific data models, communication protocols, encoding formats, etc. The GEOWOW Project - GEOSS interoperability for Weather, Ocean and Water, http://www.geowow.eu - developed a set of multidisciplinary use scenarios to advance the present GCI. This work describes the "Easy discovery and use of GEOSS resources for addressing multidisciplinary challenges related to drought scenarios" showcase demonstrated at the last GEO Plenary in Foz de Iguazu (Brazil). The scientific objectives of this showcase include: prevention and mitigation of water scarcity and drought situations, assessment of the population and geographical area potentially affected, evaluation of the possible distribution of mortality and economic loss risk, and support in building greater capacity to cope with drought. The need to address these challenges calls for producing scientifically robust and consistent information about the extent of land affected by drought and degradation. Similarly, in this context it is important: (i) to address uncertainties about the way in which various biological, physical, social, and economic factors interact each other and influence the occurrence of drought events, and (ii) to develop and test adequate indices and/or combination of them for monitoring and forecasting drought in different geographic locations and at various spatial scales (Brown et al., 2002). The scientific objectives above can be met with an increased interoperability across the multidisciplinary domains relevant to this drought scenario. In particular

  10. Evaluating Multidisciplinary Child Abuse and Neglect Teams: A Research Agenda

    ERIC Educational Resources Information Center

    Lalayants, Marina; Epstein, Irwin

    2005-01-01

    A review of child welfare research literature reveals that although multidisciplinary teams are increasingly used to investigate and intervene in child abuse and neglect cases, the field does not know enough about their structural variations, implementation processes, or effectiveness. Moreover, although articles advocating multidisciplinary teams…

  11. The Dynamics of Multidisciplinary Research Teams in Academia.

    ERIC Educational Resources Information Center

    Younglove-Webb, Julie; Gray, Barbara; Abdalla, Charles W.; Thurow, Amy Purvis

    1999-01-01

    Although multidisciplinary research teams are well-equipped to attack complex problems, actually succeeding in such endeavors is not easy. This paper explores problems that may arise in multidisciplinary research teams, develops a grounded theory, and offers suggestions to help teams reach their goals. It also offers advice to administrators for…

  12. RoboCup: Multi-disciplinary Senior Design Project.

    ERIC Educational Resources Information Center

    Elder, Kevin Lee

    A cross-college team of educators has developed a collaborative, multi-disciplinary senior design course at Ohio University. This course offers an attractive opportunity for students from a variety of disciplines to work together in a learning community to accomplish a challenging task. It provides a novel multi-disciplinary learning environment…

  13. Using Sustainability Themes and Multidisciplinary Approaches to Enhance STEM Education

    ERIC Educational Resources Information Center

    Rogers, Michael; Pfaff, Thomas; Hamilton, Jason; Erkan, Ali

    2015-01-01

    Purpose: The purpose of this paper is to report on the Multidisciplinary Sustainability Education Project (MSEP) as a framework using sustainability-themed education modules to introduce students to the need for multidisciplinary approaches to solving twenty-first-century problems while retaining traditional course strengths and content.…

  14. The Problems Facing Multidisciplinary Teams: As Perceived by Team Members.

    ERIC Educational Resources Information Center

    Pfeiffer, Steven I.

    1981-01-01

    Investigated the problems team members perceive to exist on multidisciplinary teams. Results indicated the two major areas of concern for urban, multidisciplinary team members were: too constrictive a set of team roles and goals, and teams functioning under extensive pressure with minimal support. (Author)

  15. Multidisciplinary Teamwork in Autism: Can One Size Fit All?

    ERIC Educational Resources Information Center

    Dillenburger, Karola; Röttgers, Hanns-Rüdiger; Dounavi, Katerina; Sparkman, Coleen; Keenan, Mickey; Thyer, Bruce; Nikopoulos, Christos

    2014-01-01

    Multidisciplinary practice has become an accepted approach in many education and social and health care fields. In fact, the right to a multidisciplinary assessment is enshrined in the United Nations Convention of the Rights for Persons with Disabilities (United Nations, 2007). In order to avert a "one size fits all" response to…

  16. Effectiveness of a thoracic multidisciplinary clinic in the treatment of stage III non-small-cell lung cancer

    PubMed Central

    Friedman, Eliot L; Kruklitis, Robert J; Patson, Brian J; Sopka, Dennis M; Weiss, Michael J

    2016-01-01

    Introduction The Institute of Medicine, the American Society of Clinical Oncology, and the European Society of Medical Oncology promote a multidisciplinary approach for the treatment of cancer. Stage III non-small-cell lung cancer (NSCLC) represents a heterogeneous group of diseases necessitating coordination of care among medical, radiation, and surgical oncology. The optimal care of stage III NSCLC underscores the need for a multidisciplinary approach. Methods From tumor registry data, we identified all cases of stage III NSCLC seen at Lehigh Valley Health Network between March 2010 and March 2013. The care received by patients when seen in the thoracic multidisciplinary clinic (MDC) was compared with the care received when not seen in the thoracic MDC. Results All patients seen in the MDC, compared to <50% of patients seen outside the MDC, were evaluated by more than one physician prior to beginning the treatment. Time to initiate treatment was shorter in MDC patients than in non-MDC patients. Patients seen in the MDC had a greater concordance with clinical pathways. A greater percentage of patients seen in the thoracic MDC had pathologic staging of their mediastinum. Patients seen in the MDC were more likely to receive all of their care at Lehigh Valley Health Network. Conclusion Multidisciplinary care is essential in the treatment of patients with stage III NSCLC. Greater utilization of MDCs for this complex group of patients will result in more efficient coordination of care, pretreatment evaluation, and therapy, which in turn should translate to improve patients’ outcomes. PMID:27358568

  17. A Review of Multidisciplinary Interventions in Atopic Dermatitis

    PubMed Central

    Spielman, Sara C.; LeBovidge, Jennifer S.; Timmons, Karol G.; Schneider, Lynda C.

    2015-01-01

    Multidisciplinary interventions have been developed for patients with atopic dermatitis (AD) and their families, with the aim of improving outcomes such as disease control, adherence, and quality of life. We reviewed the content of different multidisciplinary approaches to intervention for AD and evidence for their impact on key outcome measures. We also provided data from our multidisciplinary outpatient program for pediatric AD. Studies included in the review suggest benefits of multidisciplinary interventions as models of treatment or adjuncts to standard medical care, with a positive impact on outcomes including disease severity and itching/scratching. There were limitations to existing studies, including heterogeneous methods used to assess quality of life outcomes across studies and lack of controlled studies assessing the outcome of clinical care programs. Further research will be useful in assessing the impact of multidisciplinary interventions on important outcomes such as treatment adherence and sleep, identifying the elements of multidisciplinary interventions that are most critical for improved outcomes, and identifying the best candidates for multidisciplinary intervention approaches. PMID:26239470

  18. Multidisciplinary Russian biomedical research in space

    NASA Astrophysics Data System (ADS)

    Orlov, O. I.; Sychev, V. N.; Samarin, G. I.; Ilyin, E. A.; Belakovskiy, M. S.; Kussmaul, A. R.

    2014-08-01

    Research activities on a comprehensive multidisciplinary program are vital for enhancement of the system of crew's medical care, environmental health and hygiene in space missions. The primary goal of the program must be identification of patterns, intensity and dynamics of structural and functional shifts in organism induced by an aggregate of spaceflight factors including microgravity, isolation, artificial environment, space radiation, etc. Also, the program must pursue differential assessment of emerging deviations from the standpoint of adequacy to the spaceflight conditions and prospects of returning to Earth and guide the development of principles, methods and techniques necessary to maintain health and working capacity of humans during short- and long-duration missions and on return to Earth. Over 50 years, since 1963, the IBMP researchers apply systemic and innovational approaches to fundamental and exploratory studies in the fields of medical sciences, radiation biology, engineering science, biotechnology, etc. with participation of various biological specimens and human volunteers. Investigations aboard manned spacecrafts and biological satellites as well as in ground-based laboratories further enhancement of the medical care system for crews on orbital and remote space missions; they give insight into the fundamental problems of gravitational physiology and biology, psychophysiology, radiation biology, and contribute thereby to the development of knowledge, methods and technologies, as well as medical and scientific equipment.

  19. The complexity of globus: a multidisciplinary perspective.

    PubMed

    Selleslagh, Margot; van Oudenhove, Lukas; Pauwels, Ans; Tack, Jan; Rommel, Nathalie

    2014-04-01

    Globus is a topic of interest for many specialties including otorhinolaryngology, gastroenterology and psychiatry/psychosomatic medicine, but, although many hypotheses have been suggested, key questions about its aetiology remain. This Review provides an overview of the extensive literature concerning this topic and discusses the quality of the evidence to date. Globus has been associated with oropharyngeal structural lesions, upper oesophageal sphincter disorders, oesophageal disorders, GERD, psychosocial factors and psychiatric comorbidity. However, findings are often contradictory and the literature remains highly inconclusive. Indeed, with the exception of patients with structural-based globus, the Rome III criteria for functional globus only apply to a subgroup of patients with idiopathic globus. In clinical reality, there exists a group of patients who present with idiopathic (nonstructural) globus, but nevertheless have dysphagia, odynophagia or GERD-exclusion criteria for globus diagnosis according to Rome III. The symptomatology of patients with globus might be broader than previously thought. It is therefore crucial to approach globus not from one single perspective, but from a multifactorial point of view, with focus on the coexistence and/or interactions of different mechanisms in globus pathogenesis. This approach could be translated to clinical practice by adopting a multidisciplinary method to patients presenting with globus. PMID:24296583

  20. Multi-Disciplinary System Reliability Analysis

    NASA Technical Reports Server (NTRS)

    Mahadevan, Sankaran; Han, Song

    1997-01-01

    The objective of this study is to develop a new methodology for estimating the reliability of engineering systems that encompass multiple disciplines. The methodology is formulated in the context of the NESSUS probabilistic structural analysis code developed under the leadership of NASA Lewis Research Center. The NESSUS code has been successfully applied to the reliability estimation of a variety of structural engineering systems. This study examines whether the features of NESSUS could be used to investigate the reliability of systems in other disciplines such as heat transfer, fluid mechanics, electrical circuits etc., without considerable programming effort specific to each discipline. In this study, the mechanical equivalence between system behavior models in different disciplines are investigated to achieve this objective. A new methodology is presented for the analysis of heat transfer, fluid flow, and electrical circuit problems using the structural analysis routines within NESSUS, by utilizing the equivalence between the computational quantities in different disciplines. This technique is integrated with the fast probability integration and system reliability techniques within the NESSUS code, to successfully compute the system reliability of multi-disciplinary systems. Traditional as well as progressive failure analysis methods for system reliability estimation are demonstrated, through a numerical example of a heat exchanger system involving failure modes in structural, heat transfer and fluid flow disciplines.

  1. A Collaborative, Multidisciplinary Environment for Coastal Science

    NASA Astrophysics Data System (ADS)

    Graves, S. J.; Harper, S.; Maskey, M.; Twilley, R.; McAnally, B.

    2011-12-01

    The Northern Gulf Coastal Hazards Collaboratory (NG-CHC); a collaborative environment for the coastal hazards research community in Louisiana, Mississippi, and Alabama; is being developed to advance the science and engineering of coastal hazards across the tri-state region and address problems of major national importance, including engineering design, coastal system response, and risk management of coastal hazards. NG-CHC aims to accelerate the research process by providing cyberinfrastructure for simulating coastal hazards in a multidisciplinary environment, enhancing the linkages between modeling and observations and allowing researchers to find and share data and information. In addition to serving as a community portal, the extensible environment allows researchers to organize, discover, share and reuse information about data, models, tools and other resources; manage project activities; discuss results with collaborators; view publications, presentations and other documents; and track the history of project activities. The environment also provides an education and outreach area for increasing public knowledge and understanding, with project information, educational tools, and learning modules. Since communication is at the heart of science, these technologies provide researchers with easy mechanisms to share ideas, data, and findings. By enabling the close interaction among scientists and enhancing productivity with tools and services, the collaboration environment frees the researcher from the complexities of sharing and using information, allowing him to concentrate on science. This cyberinfrastructure can be applied in many domains to stimulate knowledge discovery and breakthroughs in a range of fields.

  2. Recent advances in multidisciplinary optimization of rotorcraft

    NASA Technical Reports Server (NTRS)

    Adelman, Howard M.; Walsh, Joanne L.; Pritchard, Jocelyn I.

    1992-01-01

    A joint activity involving NASA and Army researchers at NASA LaRC to develop optimization procedures to improve the rotor blade design process by integrating appropriate disciplines and accounting for all of the important interactions among the disciplines is described. The disciplines involved include rotor aerodynamics, rotor dynamics, rotor structures, airframe dynamics, and acoustics. The work is focused on combining these five key disciplines in an optimization procedure capable of designing a rotor system to satisfy multidisciplinary design requirements. Fundamental to the plan is a three-phased approach. In phase 1, the disciplines of blade dynamics, blade aerodynamics, and blade structure are closely coupled while acoustics and airframe dynamics are decoupled and are accounted for as effective constraints on the design for the first three disciplines. In phase 2, acoustics is integrated with the first three disciplines. Finally, in phase 3, airframe dynamics is integrated with the other four disciplines. Representative results from work performed to date are described. These include optimal placement of tuning masses for reduction of blade vibratory shear forces, integrated aerodynamic/dynamic optimization, and integrated aerodynamic/dynamic/structural optimization. Examples of validating procedures are described.

  3. An initiative in multidisciplinary optimization of rotorcraft

    NASA Technical Reports Server (NTRS)

    Adelman, Howard M.; Mantay, Wayne R.

    1988-01-01

    Described is a joint NASA/Army initiative at the Langley Research Center to develop optimization procedures aimed at improving the rotor blade design process by integrating appropriate disciplines and accounting for important interactions among the disciplines. The activity is being guided by a Steering Committee made up of key NASA and Army researchers and managers. The committee, which has been named IRASC (Integrated Rotorcraft Analysis Steering Committee), has defined two principal foci for the activity: a white paper which sets forth the goals and plans of the effort; and a rotor design project which will validate the basic constituents, as well as the overall design methodology for multidisciplinary optimization. The paper describes the optimization formulation in terms of the objective function, design variables, and constraints. Additionally, some of the analysis aspects are discussed and an initial attempt at defining the interdisciplinary couplings is summarized. At this writing, some significant progress has been made, principally in the areas of single discipline optimization. Results are given which represent accomplishments in rotor aerodynamic performance optimization for minimum hover horsepower, rotor dynamic optimization for vibration reduction, and rotor structural optimization for minimum weight.

  4. An initiative in multidisciplinary optimization of rotorcraft

    NASA Technical Reports Server (NTRS)

    Adelman, Howard M.; Mantay, Wayne R.

    1989-01-01

    Described is a joint NASA/Army initiative at the Langley Research Center to develop optimization procedures aimed at improving the rotor blade design process by integrating appropriate disciplines and accounting for important interactions among the disciplines. The activity is being guided by a Steering Committee made up of key NASA and Army researchers and managers. The committee, which has been named IRASC (Integrated Rotorcraft Analysis Steering Committee), has defined two principal foci for the activity: a white paper which sets forth the goals and plans of the effort; and a rotor design project which will validate the basic constituents, as well as the overall design methodology for multidisciplinary optimization. The optimization formulation is described in terms of the objective function, design variables, and constraints. Additionally, some of the analysis aspects are discussed and an initial attempt at defining the interdisciplinary couplings is summarized. At this writing, some significant progress has been made, principally in the areas of single discipline optimization. Results are given which represent accomplishments in rotor aerodynamic performance optimization for minimum hover horsepower, rotor dynamic optimization for vibration reduction, and rotor structural optimization for minimum weight.

  5. Multidisciplinary Management of Soft Tissue Sarcoma

    PubMed Central

    Nystrom, Lukas M.; Reimer, Nickolas B.; Reith, John D.; Dang, Long; Zlotecki, Robert A.; Scarborough, Mark T.; Gibbs, C. Parker

    2013-01-01

    Soft tissue sarcoma is a rare malignancy, with approximately 11,000 cases per year encountered in the United States. It is primarily encountered in adults but can affect patients of any age. There are many histologic subtypes and the malignancy can be low or high grade. Appropriate staging work up includes a physical exam, advanced imaging, and a carefully planned biopsy. This information is then used to guide the discussion of definitive treatment of the tumor which typically involves surgical resection with a negative margin in addition to neoadjuvant or adjuvant external beam radiation. Advances in imaging and radiation therapy have made limb salvage surgery the standard of care, with local control rates greater than 90% in most modern series. Currently, the role of chemotherapy is not well defined and this treatment is typically reserved for patients with metastatic or recurrent disease and for certain histologic subtypes. The goal of this paper is to review the current state of the art in multidisciplinary management of soft tissue sarcoma. PMID:23983648

  6. Design Environment for Multifidelity and Multidisciplinary Components

    NASA Technical Reports Server (NTRS)

    Platt, Michael

    2014-01-01

    One of the greatest challenges when developing propulsion systems is predicting the interacting effects between the fluid loads, thermal loads, and structural deflection. The interactions between technical disciplines often are not fully analyzed, and the analysis in one discipline often uses a simplified representation of other disciplines as an input or boundary condition. For example, the fluid forces in an engine generate static and dynamic rotor deflection, but the forces themselves are dependent on the rotor position and its orbit. It is important to consider the interaction between the physical phenomena where the outcome of each analysis is heavily dependent on the inputs (e.g., changes in flow due to deflection, changes in deflection due to fluid forces). A rigid design process also lacks the flexibility to employ multiple levels of fidelity in the analysis of each of the components. This project developed and validated an innovative design environment that has the flexibility to simultaneously analyze multiple disciplines and multiple components with multiple levels of model fidelity. Using NASA's open-source multidisciplinary design analysis and optimization (OpenMDAO) framework, this multifaceted system will provide substantially superior capabilities to current design tools.

  7. Arthrogryposis in infancy, multidisciplinary approach: case report

    PubMed Central

    2013-01-01

    Background Arthrogryposis multiplex congenita is an etiopathogenetically heterogeneous disorder characterised by non-progressive multiple intra-articular contractures, which can be recognised at birth. The frequency is estimated at 1 in 3,000 newborns. Etiopathogenesis of arthrogryposis is multifactorial. Case presentation We report first 26 weeks of life of a boy with severe arthrogryposis. Owing to the integrated rehabilitation approach and orthopaedic treatment a visible improvement in the range of motion as well as the functionality of the child was achieved. This article proposes a cooperation of various specialists: paediatrician, orthopaedist, specialist of medical rehabilitation and physiotherapist. Conclusions Rehabilitation of a child with arthrogryposis should be early, comprehensive and multidisciplinary. Corrective treatment of knee and hip joints in infants with arthrogryposis should be preceded by the ultrasound control. There are no reports in the literature on the ultrasound imaging techniques which can be used prior to the planned orthopaedic and rehabilitative treatment in infants with arthrogryposis. The experience of our team indicates that such an approach allows to minimise the diagnostic errors and to maintain an effective treatment without the risk of joint destabilisation. PMID:24215600

  8. Multidisciplinary Optimization for Aerospace Using Genetic Optimization

    NASA Technical Reports Server (NTRS)

    Pak, Chan-gi; Hahn, Edward E.; Herrera, Claudia Y.

    2007-01-01

    In support of the ARMD guidelines NASA's Dryden Flight Research Center is developing a multidisciplinary design and optimization tool This tool will leverage existing tools and practices, and allow the easy integration and adoption of new state-of-the-art software. Optimization has made its way into many mainstream applications. For example NASTRAN(TradeMark) has its solution sequence 200 for Design Optimization, and MATLAB(TradeMark) has an Optimization Tool box. Other packages, such as ZAERO(TradeMark) aeroelastic panel code and the CFL3D(TradeMark) Navier-Stokes solver have no built in optimizer. The goal of the tool development is to generate a central executive capable of using disparate software packages ina cross platform network environment so as to quickly perform optimization and design tasks in a cohesive streamlined manner. A provided figure (Figure 1) shows a typical set of tools and their relation to the central executive. Optimization can take place within each individual too, or in a loop between the executive and the tool, or both.

  9. Multidisciplinary modeling and GIS for landscape management

    SciTech Connect

    Flamm, R.O.; Turner, M.G.

    1993-12-31

    Ecological dynamics in human-influenced landscapes are strongly affected by the socioeconomic factors that influence land-use decisions. Incorporating these factors into a spatially-explicit landscape-change model requires the integration of multidisciplinary data. We developed a model that simulates the effects of land use on landscape structure in the Little Tennessee River Basin in western North Carolina. This model uses a variety of data, including interpreted remotely-sensed imagery, census and ownership maps, topography, and results from econometric models. Data are integrated by using a geographic information system and translated into a common format, maps. Simulations generate new maps of land cover representing the amount of land-cover change that occurs. With spatially-explicit projections of landscape change, issues such as biodiversity conservation, the importance of specific landscape elements to conservation goals, and long-term landscape integrity can be addressed. In order for management to use the model to address these issues, a computer-based landscape-management decision aid is being developed. This tool integrates the models, associated data bases, and a geographic information system to facilitate the evaluation of land-use decisions and management plans. This system will estimate landscape-level consequences of alternative actions and will serve to focus coordination among different land-owners and land-use interests in managing the regional landscape.

  10. Multidisciplinary management of advanced lung neuroendocrine tumors

    PubMed Central

    Ferolla, Piero; Guerrera, Francesco; Ruffini, Enrico; Travis, William D.; Rossi, Giulio; Lausi, Paolo Olivo; Oliaro, Alberto

    2015-01-01

    The optimal clinical management of aggressive/advanced lung neuroendocrine tumors (NETs) is still debated, due to their rarity and the lack of prospective randomized studies. Results derive from retrospective mono-Institutional series, and few dedicated prospective trials, recently designed, are still ongoing. In low-grade tumors [bronchial carcinoids (BCs)] surgery, whenever feasible, remains the mainstay of treatment, and chemo/radiotherapy (RT) should be reserved to progressive diseases (PD). In case of resected N1-N2 BCs, a “watch and see” policy associated with a close clinical/radiological follow-up is recommended. Somatostatin analogs (SSA) seem to be effective in controlling BCs associated endocrine syndromes, while SSA antiproliferative effect has also been reported in the past. Targeted therapy with new drugs (Everolimus) seems to be very promising, but further trials are needed. Surgery alone is not sufficient to treat high-grade NETs: adjuvant CT is required also in early stages. Platinum-Etoposide regimen demonstrated to be the most effective; irinotecan and other biological drugs are considered very promising. In conclusion, the management of advanced lung NETs should be individualized by multidisciplinary teams which include Medical and Radiation Oncologists, Surgeons, Pathologists, Pulmonologists, Endocrinologists, Interventional Radiologists, and the prognosis is mainly dependent on tumor grade and its anatomical extent. PMID:25984363

  11. Coupled multi-disciplinary composites behavior simulation

    NASA Technical Reports Server (NTRS)

    Singhal, Surendra N.; Murthy, Pappu L. N.; Chamis, Christos C.

    1993-01-01

    The capabilities of the computer code CSTEM (Coupled Structural/Thermal/Electro-Magnetic Analysis) are discussed and demonstrated. CSTEM computationally simulates the coupled response of layered multi-material composite structures subjected to simultaneous thermal, structural, vibration, acoustic, and electromagnetic loads and includes the effect of aggressive environments. The composite material behavior and structural response is determined at its various inherent scales: constituents (fiber/matrix), ply, laminate, and structural component. The thermal and mechanical properties of the constituents are considered to be nonlinearly dependent on various parameters such as temperature and moisture. The acoustic and electromagnetic properties also include dependence on vibration and electromagnetic wave frequencies, respectively. The simulation is based on a three dimensional finite element analysis in conjunction with composite mechanics and with structural tailoring codes, and with acoustic and electromagnetic analysis methods. An aircraft engine composite fan blade is selected as a typical structural component to demonstrate the CSTEM capabilities. Results of various coupled multi-disciplinary heat transfer, structural, vibration, acoustic, and electromagnetic analyses for temperature distribution, stress and displacement response, deformed shape, vibration frequencies, mode shapes, acoustic noise, and electromagnetic reflection from the fan blade are discussed for their coupled effects in hot and humid environments. Collectively, these results demonstrate the effectiveness of the CSTEM code in capturing the coupled effects on the various responses of composite structures subjected to simultaneous multiple real-life loads.

  12. Multidisciplinary pediatric brain tumor clinics: the key to successful treatment?

    PubMed

    Abdel-Baki, Mohamed S; Hanzlik, Emily; Kieran, Mark W

    2015-01-01

    Tumors of the CNS are the most common solid tumors diagnosed in childhood. As technology and research in cancer care are advancing, more specialties are involved in the diagnosis, treatment and follow-up of children with brain tumors. Multidisciplinary clinics have become the standard of care for cancer care throughout the USA, and specialty clinics focused on particular cancer types are gaining attention in improving the patient outcomes and satisfaction. We will discuss the role of multidisciplinary clinics, in an attempt to create preliminary guidelines on establishing and maintaining a multidisciplinary brain tumor clinic in order to optimize the care of the patients and their families. PMID:25923018

  13. Challenges in integrating multidisciplinary data into a single e-infrastructure

    NASA Astrophysics Data System (ADS)

    Atakan, Kuvvet; Jeffery, Keith G.; Bailo, Daniele; Harrison, Matthew

    2015-04-01

    The European Plate Observing System (EPOS) aims to create a pan-European infrastructure for solid Earth science to support a safe and sustainable society. The mission of EPOS is to monitor and understand the dynamic and complex Earth system by relying on new e-science opportunities and integrating diverse and advanced Research Infrastructures in Europe for solid Earth Science. EPOS will enable innovative multidisciplinary research for a better understanding of the Earth's physical and chemical processes that control earthquakes, volcanic eruptions, ground instability and tsunami as well as the processes driving tectonics and Earth's surface dynamics. EPOS will improve our ability to better manage the use of the subsurface of the Earth. Through integration of data, models and facilities EPOS will allow the Earth Science community to make a step change in developing new concepts and tools for key answers to scientific and socio-economic questions concerning geo-hazards and geo-resources as well as Earth sciences applications to the environment and to human welfare. EPOS is now getting into its Implementation Phase (EPOS-IP). One of the main challenges during the implementation phase is the integration of multidisciplinary data into a single e-infrastructure. Multidisciplinary data are organized and governed by the Thematic Core Services (TCS) and are driven by various scientific communities encompassing a wide spectrum of Earth science disciplines. TCS data, data products and services will be integrated into a platform "the ICS system" that will ensure their interoperability and access to these services by the scientific community as well as other users within the society. This requires dedicated tasks for interactions with the various TCS-WPs, as well as the various distributed ICS (ICS-Ds), such as High Performance Computing (HPC) facilities, large scale data storage facilities, complex processing and visualization tools etc. Computational Earth Science (CES

  14. Endemic cretinism in Thailand: a multidisciplinary survey.

    PubMed

    Rajatanavin, R; Chailurkit, L; Winichakoon, P; Mahachoklertwattana, P; Soranasataporn, S; Wacharasin, R; Chaisongkram, V; Amatyakul, P; Wanarata, L

    1997-10-01

    Endemic cretinism has been classified into neurological and myxedematous types. Profound mental deficiency, deaf-mutism and cerebral diplegia are predominantly found in the former. The latter have been described as less mentally retarded but with severe growth retardation and myxedematous features. The pathogenesis of different clinical types of endemic cretinism is still unclear. Recently, a unifying hypothesis suggested that iodine deficiency, severe enough to cause maternal and fetal hypothyroxinemia, results in neurological defects in all cretins. We conducted the present study in northern Thailand to determine the validity of this hypothesis in another geographical area. The study consisted of a multidisciplinary survey on 112 endemic cretins aged 2-66 years in Nan. They were categorized clinically into three types of endemic cretins, neurological (n = 57), myxedematous (n = 19) and mixed form (n = 36). The subjects were generally short and the majority had severe mental retardation (mean intellectual quotient (I.Q.) 30.8 +/- 8.8), psychomotor defect and profound sensorineural hearing loss. The I.Q. score and proportion of cretins with sensorineural hearing loss and psychomotor defect were similar among the three types of cretins. The most frequent neurological abnormalities were spasticity, hyper-reflexia, the presence of primitive reflexes and gait disturbance. These abnormalities were distributed equally among the three types of endemic cretins. Delayed skeletal maturation and abnormal epiphysis were also present in all types of cretins. However, myxedematous cretins were shorter (P < 0.01), having more myxedematous features (P < 0.05 to P < 0.001) and less sexual maturation (P < 0.05). Thyroid volume was lower in cretins with hypothyroidism (P < 0.01). In conclusion, our findings support the hypothesis that neurological features are present in all types of cretins, and are the consequence of maternal and fetal hypothyroxinemia due to severe iodine

  15. Multi-disciplinary optimization of aeroservoelastic systems

    NASA Technical Reports Server (NTRS)

    Karpel, Mardechay

    1992-01-01

    The purpose of the research project was to continue the development of new methods for efficient aeroservoelastic analysis and optimization. The main targets were as follows: to complete the development of analytical tools for the investigation of flutter with large stiffness changes; to continue the work on efficient continuous gust response and sensitivity derivatives; and to advance the techniques of calculating dynamic loads with control and unsteady aerodynamic effects. An efficient and highly accurate mathematical model for time-domain analysis of flutter during which large structural changes occur was developed in cooperation with Carol D. Wieseman of NASA LaRC. The model was based on the second-year work 'Modal Coordinates for Aeroelastic Analysis with Large Local Structural Variations'. The work on continuous gust response was completed. An abstract of the paper 'Continuous Gust Response and Sensitivity Derivatives Using State-Space Models' was submitted for presentation in the 33rd Israel Annual Conference on Aviation and Astronautics, Feb. 1993. The abstract is given in Appendix A. The work extends the optimization model to deal with continuous gust objectives in a way that facilitates their inclusion in the efficient multi-disciplinary optimization scheme. Currently under development is a work designed to extend the analysis and optimization capabilities to loads and stress considerations. The work is on aircraft dynamic loads in response to impulsive and non-impulsive excitation. The work extends the formulations of the mode-displacement and summation-of-forces methods to include modes with significant local distortions, and load modes. An abstract of the paper,'Structural Dynamic Loads in Response to Impulsive Excitation' is given in appendix B. Another work performed this year under the Grant was 'Size-Reduction Techniques for the Determination of Efficient Aeroservoelastic Models' given in Appendix C.

  16. Application of multidisciplinary analysis to gene expression.

    SciTech Connect

    Wang, Xuefel; Kang, Huining; Fields, Chris; Cowie, Jim R.; Davidson, George S.; Haaland, David Michael; Sibirtsev, Valeriy; Mosquera-Caro, Monica P.; Xu, Yuexian; Martin, Shawn Bryan; Helman, Paul; Andries, Erik; Ar, Kerem; Potter, Jeffrey; Willman, Cheryl L.; Murphy, Maurice H.

    2004-01-01

    Molecular analysis of cancer, at the genomic level, could lead to individualized patient diagnostics and treatments. The developments to follow will signal a significant paradigm shift in the clinical management of human cancer. Despite our initial hopes, however, it seems that simple analysis of microarray data cannot elucidate clinically significant gene functions and mechanisms. Extracting biological information from microarray data requires a complicated path involving multidisciplinary teams of biomedical researchers, computer scientists, mathematicians, statisticians, and computational linguists. The integration of the diverse outputs of each team is the limiting factor in the progress to discover candidate genes and pathways associated with the molecular biology of cancer. Specifically, one must deal with sets of significant genes identified by each method and extract whatever useful information may be found by comparing these different gene lists. Here we present our experience with such comparisons, and share methods developed in the analysis of an infant leukemia cohort studied on Affymetrix HG-U95A arrays. In particular, spatial gene clustering, hyper-dimensional projections, and computational linguistics were used to compare different gene lists. In spatial gene clustering, different gene lists are grouped together and visualized on a three-dimensional expression map, where genes with similar expressions are co-located. In another approach, projections from gene expression space onto a sphere clarify how groups of genes can jointly have more predictive power than groups of individually selected genes. Finally, online literature is automatically rearranged to present information about genes common to multiple groups, or to contrast the differences between the lists. The combination of these methods has improved our understanding of infant leukemia. While the complicated reality of the biology dashed our initial, optimistic hopes for simple answers from

  17. Necrotizing pancreatitis: a review of multidisciplinary management.

    PubMed

    Sabo, Anthony; Goussous, Naeem; Sardana, Neeraj; Patel, Shirali; Cunningham, Steven C

    2015-03-01

    The objective of this review is to summarize the current state of the art of the management of necrotizing pancreatitis, and to clarify some confusing points regarding the terminology and diagnosis of necrotizing pancreatitis, as these points are essential for management decisions and communication between providers and within the literature. Acute pancreatitis varies widely in its clinical presentation. Despite the publication of the Atlanta guidelines, misuse of pancreatitis terminology continues in the literature and in clinical practice, especially regarding the local complications associated with severe acute pancreatitis. Necrotizing pancreatitis is a manifestation of severe acute pancreatitis associated with significant morbidity and mortality. Diagnosis is aided by pancreas-protocol computed tomography or magnetic resonance imaging, ideally 72 h after onset of symptoms to achieve the most accurate characterization of pancreatic necrosis. The extent of necrosis correlates well with the incidence of infected necrosis, organ failure, need for debridement, and morbidity and mortality. Having established the diagnosis of pancreatic necrosis, goals of appropriately aggressive resuscitation should be established and adhered to in a multidisciplinary approach, ideally at a high-volume pancreatic center. The role of antibiotics is determined by the presence of infected necrosis. Early enteral feeds improve outcomes compared with parenteral nutrition. Pancreatic necrosis is associated with a multitude of complications which can lead to long-term morbidity or mortality. Interventional therapy should be guided by available resources and the principle of a minimally invasive approach. When open debridement is necessary, it should be delayed at least 3-6 weeks to allow demarcation of necrotic from viable tissue. PMID:25791545

  18. Establishing a multidisciplinary academic cosmetic center.

    PubMed

    Rao, Venkat K; Schmid, Daniel B; Hanson, Summer E; Bentz, Michael L

    2011-12-01

    The demand for cosmetic services has risen rapidly in recent years, but has slowed down with the current economic downturn. Managed care organizations and Medicare have been steadily reducing their reimbursements for physician services. The payment for reconstructive surgical procedures has been decreasing and is likely to worsen with healthcare reform, and many plastic surgery residency programs are facing fiscal challenges. An adequate volume of patients needing cosmetic services is necessary to recruit and train the best candidates to the residency programs. Self-pay patients will help ensure the fiscal viability of plastic surgery residency programs. Attracting patients to an academic healthcare center will become more difficult in a recession without the appropriate facilities, programs, and pricing strategies. Setting up a modern cosmetic services program at an academic center has some unique challenges, including funding, academic politics, and turf. The authors opened a free-standing academic multidisciplinary center at their medical school 3 years ago. The center is an off-site, 13,000-sq ft facility that includes faculty from plastic surgery, ear, nose, and throat, dermatology, and vascular surgery. In this article, the authors discuss the process of developing and executing a plan for starting an aesthetic services center in an academic setting. The financing of the center and factors in pricing services are discussed. The authors show the impact of the center on their cosmetic surgery patient volumes, resident education, and finances. They expect that their experience will be helpful to other plastic surgery programs at academic medical centers. PMID:22094775

  19. European research priorities for intracerebral haemorrhage.

    PubMed

    Steiner, Thorsten; Petersson, Jesper; Al-Shahi Salman, Rustam; Christensen, Hanne; Cordonnier, Charlotte; Csiba, Laszlo; Harnof, Sagi; Krieger, Derk; Mendelow, David; Molina, Carlos; Montaner, Joan; Overgaard, Karsten; Roine, Risto O; Schmutzhard, Erich; Tatlisumak, Turgut; Toni, Danilo; Stapf, Christian

    2011-01-01

    Over 2 million people are affected by intracerebral haemorrhage (ICH) worldwide every year, one third of them dying within 1 month, and many survivors being left with permanent disability. Unlike most other stroke types, the incidence, morbidity and mortality of ICH have not declined over time. No standardised diagnostic workup for the detection of the various underlying causes of ICH currently exists, and the evidence for medical or surgical therapeutic interventions remains limited. A dedicated European research programme for ICH is needed to identify ways to reduce the burden of ICH-related death and disability. The European Research Network on Intracerebral Haemorrhage EURONICH is a multidisciplinary academic research collaboration that has been established to define current research priorities and to conduct large clinical studies on all aspects of ICH. PMID:21986448

  20. European Research Priorities for Intracerebral Haemorrhage

    PubMed Central

    Steiner, Thorsten; Petersson, Jesper; Al-Shahi Salman, Rustam; Christensen, Hanne; Cordonnier, Charlotte; Csiba, Laszlo; Harnof, Sagi; Krieger, Derk; Mendelow, David; Molina, Carlos; Montaner, Joan; Overgaard, Karsten; Roine, Risto O.; Schmutzhard, Erich; Tatlisumak, Turgut; Toni, Danilo; Stapf, Christian

    2011-01-01

    Over 2 million people are affected by intracerebral haemorrhage (ICH) worldwide every year, one third of them dying within 1 month, and many survivors being left with permanent disability. Unlike most other stroke types, the incidence, morbidity and mortality of ICH have not declined over time. No standardised diagnostic workup for the detection of the various underlying causes of ICH currently exists, and the evidence for medical or surgical therapeutic interventions remains limited. A dedicated European research programme for ICH is needed to identify ways to reduce the burden of ICH-related death and disability. The European Research Network on Intracerebral Haemorrhage EURONICH is a multidisciplinary academic research collaboration that has been established to define current research priorities and to conduct large clinical studies on all aspects of ICH. PMID:21986448

  1. A MULTIDISCIPLINARY APPROACH TO STORMWATER MANAGEMENT AT THE WATERSHED SCALE.

    EPA Science Inventory

    Stormwater runoff from extensive impervious surfaces in urban and suburban areas has led to human safety risks and stream ecosystem impairment, triggering an interest in watershed-scale retrofit stormwater management. Such stormwater management is of multidisciplinary relevance, ...

  2. Multidisciplinary, Interdisciplinary, and Transdisciplinary Collaboration: Implications for Vocational Psychology

    ERIC Educational Resources Information Center

    Collin, Audrey

    2009-01-01

    The literature on interdisciplinarity identifies several forms of collaboration: multidisciplinary, transdisciplinary, and interdisciplinary (as bridge building or integration). To assist vocational psychology translate its interdisciplinary discourse into action, this paper uses that literature to identify the benefits, challenges and conditions…

  3. The Assessment of Hyperactivity in Preschool Populations: A Multidisciplinary Perspective.

    ERIC Educational Resources Information Center

    Rosenberg, Michael S.; And Others

    1989-01-01

    The variety of methods available for the assessment of hyperactivity in preschool populations is reviewed. Specific procedures for assessment are presented from a multidisciplinary perspective, integrating biophysical, behavioral, cognitive, and ecological models. (Author/JDD)

  4. Charting Multidisciplinary Team External Dynamics Using a Systems Thinking Approach

    NASA Technical Reports Server (NTRS)

    Barthelemy, Jean-Francois; Waszak, Martin R.; Jones, Kenneth M.; Silcox, Richard J.; Silva, Walter A.; Nowaczyk, Ronald H.

    1998-01-01

    Using the formalism provided by the Systems Thinking approach, the dynamics present when operating multidisciplinary teams are examined in the context of the NASA Langley Research and Technology Group, an R&D organization organized along functional lines. The paper focuses on external dynamics and examines how an organization creates and nurtures the teams and how it disseminates and retains the lessons and expertise created by the multidisciplinary activities. Key variables are selected and the causal relationships between the variables are identified. Five "stories" are told, each of which touches on a different aspect of the dynamics. The Systems Thinking Approach provides recommendations as to interventions that will facilitate the introduction of multidisciplinary teams and that therefore will increase the likelihood of performing successful multidisciplinary developments. These interventions can be carried out either by individual researchers, line management or program management.

  5. A MULTIDISCIPLINARY APPROACH TO STORMWATER MANAGEMENT AT THE catchment SCALE

    EPA Science Inventory

    Stormwater runoff from extensive impervious surfaces in urban and suburban areas has led to human safety risks and stream ecosystem impairment, triggering an interest in catchment-scale retrofit stormwater management. Such stormwater management is of multidisciplinary relevance, ...

  6. Supporting Multidisciplinary Science wtihin NASA's Discipline Data Systems

    NASA Technical Reports Server (NTRS)

    Preheim, L. E.

    1993-01-01

    Many current and future NASA and non-NASA missions are focusing on multidisciplinary science. The current paradigm for data identification and effective use by the NASA science community is based on the CODMAC model proposed in 1986.

  7. A Multidisciplinary Model for Undergraduate Education in Rehabilitation

    ERIC Educational Resources Information Center

    Steger, Joseph M.

    1974-01-01

    An undergraduate program oriented to developing multidisciplinary team competence in members of a variety of rehabilitation specialities is presented as an illustration of how such a model can be implemented. (Author)

  8. Multidisciplinary design optimization: An emerging new engineering discipline

    NASA Technical Reports Server (NTRS)

    Sobieszczanski-Sobieski, Jaroslaw

    1993-01-01

    This paper defines the Multidisciplinary Design Optimization (MDO) as a new field of research endeavor and as an aid in the design of engineering systems. It examines the MDO conceptual components in relation to each other and defines their functions.

  9. Book review: Black bass diversity: Multidisciplinary science for conservation

    USGS Publications Warehouse

    Jelks, Howard

    2016-01-01

    Review info: Black bass diversity: Multidisciplinary science for conservation. Edited by Michael D. Tringali, James M. Long, Timothy W. Birdsong, and Michael S. Allen, 2015. ISBN: 978-1-934874-40-0, 685 pp.

  10. Improving Nurse-Physician Teamwork: A Multidisciplinary Collaboration.

    PubMed

    Streeton, Abigail; Bisbey, Cindy; O'Neill, Carrie; Allen, Danielle; O'Hara, Sara; Weinhold, Megan; Miller, Jenna; Bursiek, April; Grubbs, Pamela

    2016-01-01

    Nurses surveyed on an inpatient gynecology surgical unit suggested communication and teamwork between nurses and physicians could be improved. To enhance teamwork, a multidisciplinary collaboration committee of nurses and physicians was created. PMID:27044126

  11. Responding to the Challenge of Survival: Multidisciplinary Language Courses

    ERIC Educational Resources Information Center

    Champagne, Roland A.

    1978-01-01

    Multidisciplinary language courses offer hope for integrating language courses into a university undergraduate curriculum. Such courses use a target language, such as French, to explore problems in another discipline. (Author)

  12. RETROFIT STORMWATER MANAGEMENT: NAVIGATING MULTIDISCIPLINARY HURDLES AT THE WATERSHED SCALE

    EPA Science Inventory

    Stormwater runoff from extensive impervious surfaces in urban and suburban areas has led to human safety risks and stream ecosystem impairment, triggering an interest in watershed-scale retrofit stormwater management. Such stormwater management is of multidisciplinary relevance, ...

  13. An Overview of Three Approaches to Multidisciplinary Aeropropulsion Simulations

    NASA Technical Reports Server (NTRS)

    Lawrence, Charles

    1997-01-01

    The broad scope of aeropropulsion multidisciplinary applications necessitates that a collection of approaches, with distinct capabilities, be developed. Three general approaches to multidisciplinary simulations have been identified. The three approaches; loosely coupled, coupled process, and multiphysics, provide a comprehensive collection of capabilities for multidisciplinary aeropropulsion analysis. At the data access level, or loosely coupled approach of coupling, existing disciplinary simulations are run, data is generated, and made available and used for subsequent analysis. The data must be in the correct format for implementation by the subsequent analysis but the subsequent code need not directly communicate with the previous code. At the process level, or coupled process approach of coupling, individual disciplinary codes are used, similarly to the loosely coupled approach, however, in the coupled process approach the disciplinary codes need to run concurrently with each other. The system of equation coupled approach, or multiphysics approach, addresses those applications whose characteristics require that the disciplines be coupled at the fundamental equation level to accurately, or more efficiently, capture the multidisciplinary physics of the problem. No one of these approaches, by itself, addresses all of the community needs in this area. However, collectively the three approaches encompass all of the multidisciplinary applications which have been identified thus far. Multiple approaches to multidisciplinary simulations will be needed as long as the applications and their requirements remain as diverse as they currently are today.

  14. Landslide risk analysis: a multi-disciplinary methodological approach

    NASA Astrophysics Data System (ADS)

    Sterlacchini, S.; Frigerio, S.; Giacomelli, P.; Brambilla, M.

    2007-11-01

    This study describes an analysis carried out within the European community project "ALARM" (Assessment of Landslide Risk and Mitigation in Mountain Areas, 2004) on landslide risk assessment in the municipality of Corvara in Badia, Italy. This mountainous area, located in the central Dolomites (Italian Alps), poses a significant landslide hazard to several man-made and natural objects. Three parameters for determining risk were analysed as an aid to preparedness and mitigation planning: event occurrence probability, elements at risk, and the vulnerability of these elements. Initially, a landslide hazard scenario was defined; this step was followed by the identification of the potential vulnerable elements, by the estimation of the expected physical effects, due to the occurrence of a damaging phenomenon, and by the analysis of social and economic features of the area. Finally, a potential risk scenario was defined, where the relationships between the event, its physical effects, and its economic consequences were investigated. People and public administrators with training and experience in local landsliding and slope processes were involved in each step of the analysis. A "cause-effect" correlation was applied, derived from the "dose-response" equation initially used in the biological sciences and then adapted by economists for the assessment of environmental risks. The relationship was analysed from a physical point of view and the cause (the natural event) was correlated to the physical effects, i.e. the aesthetic, functional, and structural damage. An economic evaluation of direct and indirect damage was carried out considering the assets in the affected area (i.e., tourist flows, goods, transport and the effect on other social and economic activities). This study shows the importance of indirect damage, which is as significant as direct damage. The total amount of direct damage was estimated in 8 913 000 €; on the contrary, indirect damage ranged considerably

  15. Multidisciplinary design optimization using genetic algorithms

    NASA Astrophysics Data System (ADS)

    Unal, Resit

    1994-12-01

    Multidisciplinary design optimization (MDO) is an important step in the conceptual design and evaluation of launch vehicles since it can have a significant impact on performance and life cycle cost. The objective is to search the system design space to determine values of design variables that optimize the performance characteristic subject to system constraints. Gradient-based optimization routines have been used extensively for aerospace design optimization. However, one limitation of gradient based optimizers is their need for gradient information. Therefore, design problems which include discrete variables can not be studied. Such problems are common in launch vehicle design. For example, the number of engines and material choices must be integer values or assume only a few discrete values. In this study, genetic algorithms are investigated as an approach to MDO problems involving discrete variables and discontinuous domains. Optimization by genetic algorithms (GA) uses a search procedure which is fundamentally different from those gradient based methods. Genetic algorithms seek to find good solutions in an efficient and timely manner rather than finding the best solution. GA are designed to mimic evolutionary selection. A population of candidate designs is evaluated at each iteration, and each individual's probability of reproduction (existence in the next generation) depends on its fitness value (related to the value of the objective function). Progress toward the optimum is achieved by the crossover and mutation operations. GA is attractive since it uses only objective function values in the search process, so gradient calculations are avoided. Hence, GA are able to deal with discrete variables. Studies report success in the use of GA for aircraft design optimization studies, trajectory analysis, space structure design and control systems design. In these studies reliable convergence was achieved, but the number of function evaluations was large compared

  16. Multi-Disciplinary Design Optimization Using WAVE

    NASA Technical Reports Server (NTRS)

    Irwin, Keith

    2000-01-01

    develop an associative control structure (framework) in the UG WAVE environment enabling multi-disciplinary design of turbine propulsion systems. The capabilities of WAVE were evaluated to assess its use as a rapid optimization and productivity tool. This project also identified future WAVE product enhancements that will make the tool still more beneficial for product development.

  17. Multidisciplinary design optimization using genetic algorithms

    NASA Technical Reports Server (NTRS)

    Unal, Resit

    1994-01-01

    Multidisciplinary design optimization (MDO) is an important step in the conceptual design and evaluation of launch vehicles since it can have a significant impact on performance and life cycle cost. The objective is to search the system design space to determine values of design variables that optimize the performance characteristic subject to system constraints. Gradient-based optimization routines have been used extensively for aerospace design optimization. However, one limitation of gradient based optimizers is their need for gradient information. Therefore, design problems which include discrete variables can not be studied. Such problems are common in launch vehicle design. For example, the number of engines and material choices must be integer values or assume only a few discrete values. In this study, genetic algorithms are investigated as an approach to MDO problems involving discrete variables and discontinuous domains. Optimization by genetic algorithms (GA) uses a search procedure which is fundamentally different from those gradient based methods. Genetic algorithms seek to find good solutions in an efficient and timely manner rather than finding the best solution. GA are designed to mimic evolutionary selection. A population of candidate designs is evaluated at each iteration, and each individual's probability of reproduction (existence in the next generation) depends on its fitness value (related to the value of the objective function). Progress toward the optimum is achieved by the crossover and mutation operations. GA is attractive since it uses only objective function values in the search process, so gradient calculations are avoided. Hence, GA are able to deal with discrete variables. Studies report success in the use of GA for aircraft design optimization studies, trajectory analysis, space structure design and control systems design. In these studies reliable convergence was achieved, but the number of function evaluations was large compared

  18. European landscape in astrobiology, results of the AstRoMap consultation

    NASA Astrophysics Data System (ADS)

    Horneck, Gerda; Rettberg, Petra; Walter, Nicolas; Gomez, Felipe

    2015-05-01

    Astrobiology is a multidisciplinary field of research, which encompasses scientists ranging from cosmology, astronomy, planetary sciences, physics, chemistry, geology, paleontology to biology. In order to map the existing astrobiological expertise in Europe a comprehensive community consultation has been performed within the AstRoMap (Astrobiology Road Mapping) project that is supported by the European Commission FP7 framework. From this information a data base of scientists (European and beyond) interested in astrobiology and planetary exploration (see:

  19. Executive Coaching: Study of the Evolution of the Program at a Top European Business School

    ERIC Educational Resources Information Center

    Kim, Hyun Jung

    2011-01-01

    To understand how tensions caused by the multidisciplinary nature of executive coaching are perceived and overcome, this modified ethnographic study was conducted at an executive coaching program and leadership center at a prestigious European business school. This study is built on prolonged discussions on the role of psychology in executive…

  20. Informatics for multi-disciplinary ocean sciences

    NASA Astrophysics Data System (ADS)

    Pearlman, Jay; Delory, Eric; Pissierssens, Peter; Raymond, Lisa; Simpson, Pauline; Waldmann, Christoph; Williams 3rd, Albert; Yoder, Jim

    2014-05-01

    Ocean researchers must work across disciplines to provide clear and understandable assessments of the state of the ocean. With advances in technology, not only in observation, but also communication and computer science, we are in a new era where we can answer questions at the time and space scales that are relevant to our state of the art research needs. This presentation will address three areas of the informatics of the end-to-end process: sensors and information extraction in the sensing environment; using diverse data for understanding selected ocean processes; and supporting open data initiatives. A National Science Foundation funded Ocean Observations Research Coordination Network (RCN) is addressing these areas from the perspective of improving interdisciplinary research. The work includes an assessment of Open Data Access with a paper in preparation. Interoperability and sensors is a new activity that couples with European projects, COOPEUS and NeXOS, in looking at sensors and related information systems for a new generation of measurement capability. A working group on synergies of in-situ and satellite remote sensing is analyzing approaches for more effective use of these measurements. This presentation will examine the steps forward for data exchange and for addressing gaps in communication and informatics.

  1. Multidisciplinary management of heart failure just beginning in Japan.

    PubMed

    Sato, Yukihito

    2015-09-01

    The mortality associated with end-stage heart failure (HF) is high despite the development of new and increasingly effective drugs and non-pharmacological therapies. Repetitive hospitalizations predict fatal outcomes and each hospitalization should prompt individual conversations with the patient, the family, and the caregivers. A multidisciplinary disease management program promotes the education of patients and their families and modifies their behavior, with a view to ultimately improve the prognosis and quality of life. From the early to the late stages of HF, a multidisciplinary disease management program should be implemented. In Western societies this multidisciplinary management has long been debated and endorsed, in contrast to Japan, where it has just begun. In 2012, the Japanese Nursing Association launched a certification in chronic HF nursing. A Japanese version of HF disease management should soon be developed in its own social environment. PMID:25722045

  2. Multidisciplinary care for individuals with disorders of sex development

    PubMed Central

    Gomez-Lobo, Veronica

    2015-01-01

    Purpose of review Recommendations regarding the care of individuals with disorders of sex development include that care be provided by multidisciplinary teams. This article will discuss team composition and function as well as the role of the gynecologist and barriers to such care. Recent findings Many barriers to multidisciplinary care exist, but recent reports stress the roles of different team members as well as tools for planning and implementation of such a team that may help to overcome such barriers. All current recommendations include the participation of a gynecologist in the disorders of sex development team. Gynecologists are in the unique position to continue to provide care as these individuals mature into adulthood. Summary Multidisciplinary care for patients with disorders of sex development is recommended and gynecologists provide unique expertise. PMID:25110979

  3. Multidisciplinary Team Treatment of Penetrating Head and Neck Trauma.

    PubMed

    Li, Lili; Li, Hongxing; Yang, Kongbin

    2016-09-01

    Penetrating head and neck trauma could cause significant mortality because of many important structures located in the brain and neck. Although high-velocity penetrating brain injury is often reported, reports of low-velocity, combined head and neck penetrating injury are rare. Hereby, the authors present a case of an old man who had encountered a serious accident, a 29-cm iron fork penetrated into his neck, through the skull base and into brain. After treatment by multidisciplinary team, the patient was in rehabilitation. The multidisciplinary team assists rapid diagnosis and treatment of penetrating neck and head injury is the key to ensure a good outcome. Therefore, as the authors face such patients again, a multidisciplinary team is needed. PMID:27428914

  4. Multi-disciplinary coupling for integrated design of propulsion systems

    NASA Technical Reports Server (NTRS)

    Chamis, C. C.; Singhal, S. N.

    1993-01-01

    Effective computational simulation procedures are described for modeling the inherent multi-disciplinary interactions for determining the true response of propulsion systems. Results are presented for propulsion system responses including multi-discipline coupling effects via (1) coupled multi-discipline tailoring, (2) an integrated system of multidisciplinary simulators, (3) coupled material-behavior/fabrication-process tailoring, (4) sensitivities using a probabilistic simulator, and (5) coupled materials/structures/fracture/probabilistic behavior simulator. The results show that the best designs can be determined if the analysis/tailoring methods account for the multi-disciplinary coupling effects. The coupling across disciplines can be used to develop an integrated interactive multi-discipline numerical propulsion system simulator.

  5. The Multidisciplinary Management of Colorectal Cancer: Present and Future Paradigms.

    PubMed

    Sievers, Chelsie K; Kratz, Jeremy D; Zurbriggen, Luke D; LoConte, Noelle K; Lubner, Sam J; Uboha, Natalya; Mulkerin, Daniel; Matkowskyj, Kristina A; Deming, Dustin A

    2016-09-01

    As treatment strategies for patients with colorectal cancer advance, there has now become an ever-increasing need for multidisciplinary teams to care for these patients. Recent investigations into the timing and duration of perioperative therapy, as well as, the rise of molecular profiling have led to more systemic chemotherapeutic options. The most efficacious use, in terms of timing and patient selection, of these therapies in the setting of modern operative and radiotherapy techniques requires the generation of care teams discussing cases at multidisciplinary conferences. This review highlights the role of multidisciplinary team conferences, advances in perioperative chemotherapy, current clinical biomarkers, and emerging therapeutic agents for molecular subtypes of metastatic colon cancer. As our understanding of relevant molecular subtypes increases and as data becomes available on treatment response, the treatment of colorectal cancer will become more precise and effective. PMID:27582648

  6. Efficient Multidisciplinary Analysis Procedure Using Multi-Level Parallelization Approach

    NASA Technical Reports Server (NTRS)

    Byun, Chansup; Hatay, Ferhat; Farhangnia, Mehrdad; Guruswamy, Guru; VanDalsem, William R. (Technical Monitor)

    1997-01-01

    Multidisciplinary applications are suitable for parallel computing environment by adopting the domain decomposition method. Immediately, a multidisciplinary application can be parallelized by solving each discipline separately. In order to perform coupled multidisciplinary analysis, coupling of each discipline can be accomplished by exchanging boundary data at the interfaces. This is regarded as discipline-level parallelization. Next level could be a "coarse-grain" parallelization of each discipline, which mainly depends on the physical geometry and nature of each discipline. For example, it is almost impossible for structured-grid based computational fluid dynamics codes to do flow analysis of an aircraft by using a single grid because of the complexity of its configuration. Thus, multi-block grid is commonly used to describe the details of complex geometry. Similarly, in structural analysis, the structure is frequently subdivided into substructures. Thus, the computation of each subdomain can be easily parallelized since each subdomain is solved separately independent of other domains. The parallelization is accomplished by solving each subdomain separately on a separate processor and exchanging the boundary conditions at domain interfaces periodically. However, the physical decomposition of the domain introduces explicit boundary conditions at the domain interfaces. This is not desirable for critical areas such as those containing shock waves or flow separations. Thus, a "fine-grain" parallelization is introduced to overcome this problem. The "fine-grain" parallelization is one that solves exactly the same system of equations of a subdomain by using more than one processors without introducing any explicit boundary conditions. An efficient multidisciplinary analysis procedure can be accomplished by successfully combining the above multi-level parallelism. A multidisciplinary analysis code, ENSAERO developed at NASA Ames Research Center is used in this study to

  7. [Multidisciplinary tailoring of therapy of metastatic colon cancer].

    PubMed

    Österlund, Pia; Isoniemi, Helena; Scheinin, Tom; Ristimäki, Ari; Lantto, Eila

    2016-01-01

    Treatment of colon cancer requires multidisciplinary team work. The multitude of therapies in metastatic colon cancer have led to longer overall survival with fewer symptoms. Median survival has increased from 5 months with the best supportive care to 30-40 months in randomized studies, even with curative treatment in some patients. Tailoring of the treatment is best done by a multidisciplinary team considering radiotherapy and operation of the primary tumor, resection of liver, lung and peritoneal metastases, medical treatment alternatives, palliative care, ablative methods etc. Without skillful surgeons, oncologists, pathologists, geneticists, radiologists etc. the best treatment opportunities may be missed. PMID:27483635

  8. Implementing effective and sustainable multidisciplinary clinical thoracic oncology programs

    PubMed Central

    Freeman, Richard K.; Krasna, Mark J.

    2015-01-01

    Three models of care are described, including two models of multidisciplinary care for thoracic malignancies. The pros and cons of each model are discussed, the evidence supporting each is reviewed, and the need for more (and better) research into care delivery models is highlighted. Key stakeholders in thoracic oncology care delivery outcomes are identified, and the need to consider stakeholder perspectives in designing, validating and implementing multidisciplinary programs as a vehicle for quality improvement in thoracic oncology is emphasized. The importance of reconciling stakeholder perspectives, and identify meaningful stakeholder-relevant benchmarks is also emphasized. Metrics for measuring program implementation and overall success are proposed. PMID:26380186

  9. Multidisciplinary Analysis and Optimization Generation 1 and Next Steps

    NASA Technical Reports Server (NTRS)

    Naiman, Cynthia Gutierrez

    2008-01-01

    The Multidisciplinary Analysis & Optimization Working Group (MDAO WG) of the Systems Analysis Design & Optimization (SAD&O) discipline in the Fundamental Aeronautics Program s Subsonic Fixed Wing (SFW) project completed three major milestones during Fiscal Year (FY)08: "Requirements Definition" Milestone (1/31/08); "GEN 1 Integrated Multi-disciplinary Toolset" (Annual Performance Goal) (6/30/08); and "Define Architecture & Interfaces for Next Generation Open Source MDAO Framework" Milestone (9/30/08). Details of all three milestones are explained including documentation available, potential partner collaborations, and next steps in FY09.

  10. Multidisciplinary analysis and synthesis - Needs and opportunities. [for aerospace design

    NASA Technical Reports Server (NTRS)

    Tolson, R. H.; Sobieszczanski-Sobieski, J.

    1985-01-01

    A comprehensive evaluation is conducted of structural analysis and synthesis opportunities which emerge through a multidisciplinary design program approach that simultaneously and interactively encompasses, in its determination of a given aircraft design, aerodynamics, structure, structural dynamics, materials, controls, and propulsion. In this way, it becomes possible to rapidly exploit technological advances in order to yield synergistic effects among configurational subsystems. The aircraft type presently considered as recipients of this treatment are commercial transports, high performance military aircraft, rotorcraft, and large space antennas, giving attention to common features among the multidisciplinary design tasks represented.

  11. A Multidisciplinary Engineering Summer School in an Industrial Setting

    ERIC Educational Resources Information Center

    Larsen, Peter Gorm; Fernandes, Joao M.; Habel, Jacek; Lehrskov, Hanne; Vos, Richard J. C.; Wallington, Oliver; Zidek, Jan

    2009-01-01

    Most university-level engineering studies produce technically skilled engineers. However, typically students face several difficulties when working in multidisciplinary teams when they initiate their industrial careers. In a globalised world, it becomes increasingly important that engineers are capable of collaborating across disciplinary…

  12. Multidisciplinary design optimization - An emerging new engineering discipline

    NASA Technical Reports Server (NTRS)

    Sobieszczanski-Sobieski, Jaroslaw

    1993-01-01

    A definition of the multidisciplinary design optimization (MDO) is introduced, and functionality and relationship of the MDO conceptual components are examined. The latter include design-oriented analysis, approximation concepts, mathematical system modeling, design space search, an optimization procedure, and a humane interface.

  13. A Multidisciplinary Approach to Literacy through Picture Books and Drama

    ERIC Educational Resources Information Center

    Burke, Anne; Peterson, Shelley Stagg

    2007-01-01

    Anne Burke and Shelley Stagg Peterson argue that "picture books offer a medium for teaching visual and critical literacy across the curriculum." To support this idea, they describe a multidisciplinary unit on World War II that pushes high school students to utilize visual and print literacies to analyze, comprehend, and relate to public events and…

  14. Multidisciplinary management of hypohydrotic ectodermal dysplasia – a case report

    PubMed Central

    Joseph, Suja; Cherackal, George J; Jacob, Jose; Varghese, Alex K

    2015-01-01

    Key Clinical Message Hypohydrotic ectodermal dysplasia is a hereditary disorder, which affects ectodermal derivatives. It manifests several abnormalities of the teeth, and is commonly inherited through female carriers. This case report presents a patient with compromised esthetics and function. A multidisciplinary approach was planned involving an oral pathologist, endodontist, orthodontist and a prosthodontist. PMID:25984305

  15. Implementing Multidisciplinary and Multi-Zonal Applications Using MPI

    NASA Technical Reports Server (NTRS)

    Fineberg, Samuel A.

    1995-01-01

    Multidisciplinary and multi-zonal applications are an important class of applications in the area of Computational Aerosciences. In these codes, two or more distinct parallel programs or copies of a single program are utilized to model a single problem. To support such applications, it is common to use a programming model where a program is divided into several single program multiple data stream (SPMD) applications, each of which solves the equations for a single physical discipline or grid zone. These SPMD applications are then bound together to form a single multidisciplinary or multi-zonal program in which the constituent parts communicate via point-to-point message passing routines. Unfortunately, simple message passing models, like Intel's NX library, only allow point-to-point and global communication within a single system-defined partition. This makes implementation of these applications quite difficult, if not impossible. In this report it is shown that the new Message Passing Interface (MPI) standard is a viable portable library for implementing the message passing portion of multidisciplinary applications. Further, with the extension of a portable loader, fully portable multidisciplinary application programs can be developed. Finally, the performance of MPI is compared to that of some native message passing libraries. This comparison shows that MPI can be implemented to deliver performance commensurate with native message libraries.

  16. Determinants of Food Safety Risks: A Multi-disciplinary Approach

    ERIC Educational Resources Information Center

    Knight, Andrew; Warland, Rex

    2005-01-01

    This research employs a multi-disciplinary approach by developing a model that draws upon psychometric, cultural, and reflexive modernization perspectives of risk perception. Using data from a 1999 national telephone survey, we tested our model on three food risks ? pesticides, Salmonella, and fat. Results showed that perceptions of risks do vary…

  17. Intergenerational Service Learning with Elders: Multidisciplinary Activities and Outcomes

    ERIC Educational Resources Information Center

    Krout, John A.; Bergman, Elizabeth; Bianconi, Penny; Caldwell, Kathryn; Dorsey, Julie; Durnford, Susan; Erickson, Mary Ann; Lapp, Julia; Monroe, Janice Elich; Pogorzala, Christine; Taves, Jessica Valdez

    2010-01-01

    This article provides an overview of the activities included in a 3-year, multidisciplinary, intergenerational service-learning project conducted as part of a Foundation for Long-Term Care Service Learning: Linking Three Generations grant. Courses from four departments (gerontology, psychology, occupational therapy, and health promotion and…

  18. Multi-Disciplinary Learning through a Database Development Project

    ERIC Educational Resources Information Center

    Ng, Vincent; Lau, Chloe; Shum, Pearl

    2012-01-01

    Recently, there are many good examples of how multi-disciplinary learning can support students to learn collaboratively and not solely focus on a single professional sector. During the Fall 2011 and Spring 2012 semesters, we have attempted to gather students studying different professional domains together. Students from the Department of…

  19. An information driven strategy to support multidisciplinary design

    NASA Technical Reports Server (NTRS)

    Rangan, Ravi M.; Fulton, Robert E.

    1990-01-01

    The design of complex engineering systems such as aircraft, automobiles, and computers is primarily a cooperative multidisciplinary design process involving interactions between several design agents. The common thread underlying this multidisciplinary design activity is the information exchange between the various groups and disciplines. The integrating component in such environments is the common data and the dependencies that exist between such data. This may be contrasted to classical multidisciplinary analyses problems where there is coupling between distinct design parameters. For example, they may be expressed as mathematically coupled relationships between aerodynamic and structural interactions in aircraft structures, between thermal and structural interactions in nuclear plants, and between control considerations and structural interactions in flexible robots. These relationships provide analytical based frameworks leading to optimization problem formulations. However, in multidisciplinary design problems, information based interactions become more critical. Many times, the relationships between different design parameters are not amenable to analytical characterization. Under such circumstances, information based interactions will provide the best integration paradigm, i.e., there is a need to model the data entities and their dependencies between design parameters originating from different design agents. The modeling of such data interactions and dependencies forms the basis for integrating the various design agents.

  20. Development of a Multidisciplinary Middle School Mathematics Infusion Model

    ERIC Educational Resources Information Center

    Russo, Maria; Hecht, Deborah; Burghardt, M. David; Hacker, Michael; Saxman, Laura

    2011-01-01

    The National Science Foundation (NSF) funded project "Mathematics, Science, and Technology Partnership" (MSTP) developed a multidisciplinary instructional model for connecting mathematics to science, technology and engineering content areas at the middle school level. Specifically, the model infused mathematics into middle school curriculum…

  1. Reflections on Knowledge Brokering within a Multidisciplinary Research Team

    ERIC Educational Resources Information Center

    Urquhart, Robin; Porter, Geoffrey A.; Grunfeld, Eva

    2011-01-01

    Knowledge brokering (KB) may be one approach of helping researchers and decision makers effectively communicate their needs and abilities, and move toward increased use of evidence in health care. A multidisciplinary research team in Nova Scotia, Canada, has created a dedicated KB position with the goal of improving access to quality colorectal…

  2. Geometric requirements for multidisciplinary analysis of aerospace-vehicle design

    NASA Technical Reports Server (NTRS)

    Smith, Robert E.; Kerr, Patirca A.

    1992-01-01

    The geometric requirements for creating surfaces and grids for multidisciplinary analysis and optimization of aerospace-vehicle designs are described. Geometric surface representations are outlined and compared. Directions for future designs are proposed. High-speed civil transport aircraft configurations are targeted to demonstrate the processes.

  3. Influence of an infectious diseases specialist on ICU multidisciplinary rounds.

    PubMed

    Gilbert, David N

    2014-01-01

    Objective. To ascertain the influence of a physician infectious diseases specialist (IDS) on antibiotic use in a medical/surgical intensive care unit. Method. Over a 5-month period, the antibiotic regimens ordered by the ICU multidisciplinary team were studied. The days of antibiotic therapy (DOT) when management decisions included an IDS were compared to DOT in the absence of an IDS. The associated treatment expense was calculated. Results. Prior to multidisciplinary rounds (MDRs), 79-80% of the patients were receiving one or more antibiotic. IDS participation occurred in 61 multidisciplinary rounding sessions. There were 384 patients who before MDRs had orders for 669 days of antimicrobial therapy (DOT). After MDRs, the antimicrobial DOT were reduced to 511 with a concomitant cost saving of $3772. There were 51 MDR sessions that occurred in the absence of the IDS. There were 352 patients who before MDRs had orders for 593 DOT. After MDRs, the DOT were reduced to 572 with a cost savings of $727. The results were normalized by number of patients evaluated with statistically greater reductions when MDRs included the IDS. In addition, the number of rounding sessions with a reduction in DOT was greater with the participation of the IDS. Conclusion. The addition of an IDS to multidisciplinary ICU patient rounds resulted in a reduction in antibiotic DOT and attendant drug expense. PMID:24860663

  4. Multidisciplinary Explorations: Bridging the Gap between Engineering and Biology

    ERIC Educational Resources Information Center

    Abraham, John

    2004-01-01

    As the evidence of the benefits of multidisciplinary education accumulates many schools and instructors are finding ways of hybridizing courses to include substantial components of what are otherwise distinct sciences. Often, such course development is done with an eye toward industry, which requires a workforce capable of synthesizing varied…

  5. The Interplay of Conflict and Analogy in Multidisciplinary Teams

    ERIC Educational Resources Information Center

    Paletz, Susannah B. F.; Schunn, Christian D.; Kim, Kevin H.

    2013-01-01

    Creative teamwork in multidisciplinary teams is a topic of interest to cognitive psychologists on the one hand, and to both social and organizational psychologists on the other. However, the interconnections between cognitive and social layers have been rarely explored. Drawing on mental models and dissonance theories, the current study takes a…

  6. Parents' Initial Perceptions of Multidisciplinary Care for Pediatric Chronic Pain

    PubMed Central

    Gorodzinsky, Ayala Y.; Tran, Susan T.; Medrano, Gustavo R.; Fleischman, Katie M.; Anderson-Khan, Kimberly J.; Ladwig, Renee J.; Weisman, Steven J.

    2012-01-01

    Chronic and recurrent pain is experienced by many children and adolescents. Treatment of chronic pain using a multidisciplinary approach has been found to be effective for treatment of chronic pain. Parent satisfaction with treatment and treatment providers highly correlates to children's treatment adherence. Parents of children treated at a multidisciplinary chronic pain clinic were interviewed following their initial appointment. Parents reported high satisfaction with treatment team members and with the treatment plan. Parents also reported appreciation of multidisciplinary structure, the high level of expertise of the team members, and the team members' genuine interest in treating their children. This increase in satisfaction when compared to previous treatment is important since increases in satisfaction may correlate with a reduction in experiences of chronic pain. Parents reported high satisfaction with interactions with treatment team members and with the treatment plan provided for their children. Parents had appreciation of multidisciplinary team structure and the high level of expertise of the team members. This increase in satisfaction when compared to treatment from previous providers is important since increases in satisfaction may correlate with an increase in children's treatment adherence and a reduction in experiences of chronic pain. PMID:22966428

  7. Expanding the Field: Revisiting Environmental Education Principles through Multidisciplinary Frameworks

    ERIC Educational Resources Information Center

    Cole, Anna Gahl

    2007-01-01

    In response to calls for discourse that builds on the substantive structure of environmental education in efforts to further the scope of the field, this article reexamines key principles of environmental education through the multidisciplinary lenses of critical pedagogy, the environmental justice movement, and more recent definitions of…

  8. The Multifile Multidisciplinary (Horizontal) Search Approach--Justification and Principles.

    ERIC Educational Resources Information Center

    Bar, Jacob

    1988-01-01

    Discusses the rationale, principles, required tools, advantages, and disadvantages of the Multifile Multidisciplinary (Horizontal) Search approach to searching online databases. It is noted that this approach is characterized by the use of a large number of files spanning a wide variety of disciplines. (12 references) (MES)

  9. Philosophizing about Teacher Dissatisfaction: A Multidisciplinary Hermeneutic Approach

    ERIC Educational Resources Information Center

    Santoro, Doris A.

    2015-01-01

    In this methodological reflection, I describe the multidisciplinary hermeneutic process of philosophizing about teacher dissatisfaction. I discuss how philosophy serves as a starting point for interpretive work based on interviews with former teachers and readings of qualitative and quantitative research on teacher attrition and dissatisfaction.…

  10. Creative Exchange: An Evolving Model of Multidisciplinary Collaboration

    ERIC Educational Resources Information Center

    Fleischmann, Katja; Hutchison, Clive

    2012-01-01

    Often the traditional creative arts curriculum does not sufficiently respond to, nor reflect, contemporary work practice. Multidisciplinary teams are now increasingly the norm in creative arts practice especially when driven by technological innovation. Drawing on contemporary research that centres on the benefits of multidisciplinary…

  11. Autism and Multidisciplinary Teamwork through the SCERTS Model

    ERIC Educational Resources Information Center

    Molteni, Paola; Guldberg, Karen; Logan, Nick

    2013-01-01

    This research investigates multidisciplinary teamwork in an English special school located in the West Midlands region of the UK. The research was carried out by Paola Molteni, a PhD student at Università Cattolica del Sacro Cuore, Milan, Karen Guldberg of the Autism Centre for Education and Research Director at the University of Birmingham School…

  12. High School Bridge Program: A Multidisciplinary STEM Research Program

    ERIC Educational Resources Information Center

    Zhe, Jiang; Doverspike, Dennis; Zhao, Julie; Lam, Paul; Menzemer, Craig

    2010-01-01

    A Science, Technology, Engineering and Math (STEM) summer Bridge Program was developed for high school students. The program was designed to encourage students to consider choosing an engineering major in college and to explore STEM as a future career. This was accomplished through a 10-week program involving multidisciplinary research activities.…

  13. Multidisciplinary interventions in the management of atopic dermatitis.

    PubMed

    LeBovidge, Jennifer S; Elverson, Wendy; Timmons, Karol G; Hawryluk, Elena B; Rea, Corinna; Lee, Margaret; Schneider, Lynda C

    2016-08-01

    Atopic dermatitis (AD) is the most common pediatric skin disease. AD has a significant effect on patient and family quality of life caused by intense pruritus, sleep disruption, dietary and nutritional concerns, and psychological stress associated with the disease and its management. Multidisciplinary approaches to AD care have been developed in appreciation of the complex interplay among biological, psychological, behavioral, and dietary factors that affect disease control and the wide range of knowledge, skills, and support that patients and families require to effectively manage and cope with this condition. Common components of multidisciplinary treatment approaches include medical evaluation and management by an AD specialist, education and nursing care, psychological and behavioral support, and nutritional assessment and guidance. Models of care include both clinical programs and structured educational groups provided as adjuncts to standard clinical care. Available evidence suggests beneficial effects of multidisciplinary interventions in improving disease severity and quality of life, particularly for patients with moderate-to-severe disease. Additional research is needed to identify the best candidates for the various multidisciplinary approaches and evaluate the cost-effectiveness of these programs. PMID:27497275

  14. Rural Development and the Campus: The Emergence of Multidisciplinary Action.

    ERIC Educational Resources Information Center

    Regional Spotlight, 1976

    1976-01-01

    Focusing upon the emergence of multidisciplinary action on southern campuses involved in rural development activities, this newsletter traces the southern rural development efforts from their inception to present times and offers projections regarding the future. Specifically, this document presents information on: the development of the land…

  15. Teaching the Multidisciplinary Team Approach in a Geriatrics Miniresidency.

    ERIC Educational Resources Information Center

    Jackson, J. Edward; And Others

    1990-01-01

    A description is provided of the miniresidency program in geriatrics at the University of California, San Diego, School of Medicine which focuses on the multidisciplinary approach to the care of geriatric patients. Observations are given as to the program's effectiveness. (GLR)

  16. Improved survival in a multidisciplinary short bowel syndrome program

    PubMed Central

    Modi, Biren P.; Langer, Monica; Ching, Y. Avery; Valim, Clarissa; Waterford, Stephen D.; Iglesias, Julie; Duro, Debora; Lo, Clifford; Jaksic, Tom; Duggan, Christopher

    2011-01-01

    Purpose Pediatric short bowel syndrome (SBS) remains a management challenge with significant mortality. In 1999, we initiated a multidisciplinary pediatric intestinal rehabilitation program. The purpose of this study was to determine if the multidisciplinary approach was associated with improved survival in this patient population. Methods The Center for Advanced Intestinal Rehabilitation includes dedicated staff in surgery, gastroenterology, nutrition, pharmacy, nursing, and social work. We reviewed the medical records of all inpatients and outpatients with severe SBS treated from 1999 to 2006. These patients were compared to a historical control group of 30 consecutive patients with severe SBS who were treated between 1986 and 1998. Results Fifty-four patients with severe SBS managed by the multidisciplinary program were identified. Median follow-up was 403 days. The mean residual small intestinal length was 70 ± 36 vs 83 ± 67 cm in the historical controls (P = NS). Mean peak direct bilirubin was 8.1 ± 7.9 vs 9.0 ± 7.4 mg/dL in controls (P = NS). Full enteral nutrition was achieved in 36 (67%) of 54 patients with severe SBS vs 20 (67%) of 30 patients in the control group (P = NS). The overall survival rate, however, was 89% (48/54), which is significantly higher than in the historical controls (70%, 21/30; P < .05). Conclusions A multidisciplinary approach to intestinal rehabilitation allows for fully integrated care of inpatients and outpatients with SBS by fostering coordination of surgical, medical, and nutritional management. Our experience with 2 comparable cohorts demonstrates that this multidisciplinary approach is associated with improved survival. PMID:18206449

  17. Monitoring of gas and seismic energy release: new results from the multi-parametric benthic observatory SN-4 at MARsite location (Gulf of Izmit, Turkey)

    NASA Astrophysics Data System (ADS)

    Embriaco, Davide; Marinaro, Giuditta; Frugoni, Francesco; Monna, Stephen; Etiope, Giuseppe; Gasperini, Luca; Polonia, Alina; Del Bianco, Fabrizio; Namık Çaǧatay, M.; Ulgen, Umut B.; Favali, Paolo

    2014-05-01

    Episodic gas seepage occurs at the seafloor in the Gulf of Izmit (Sea of Marmara, NW Turkey) along the submerged segment of the North Anatolian Fault (NAF), which ruptured during the 1999 Mw7.4 Izmit earthquake, and caused tectonic loading of the fault segment in front of the Istanbul metropolitan area. Marmara site was selected as one EMSO (European Multidisciplinary Seafloor and water column Observatory) node where establish a permanent sea-bottom observatory. An autonomous and long-term multiparametric benthic observatory (SN-4) was deployed in order to study gas seepage and seismic energy release along the NAF. SN-4 operated in the gulf at the western end of the 1999 Izmit earthquake rupture for about one-year at 166 m water depth. The SN-4 payload included a three-component broad-band seismometer, as well as gas and oceanographic sensors. We analysed data collected continuously for 161 days in the first part of the experiment, from October 2009 to March 2010. The main objective of our work was to verify whether tectonic deformation along the NAF could trigger methane seepage. Results from the SN-4 experiment in the Sea of Marmara suggest that neither low-magnitude local seismicity, nor regional events affect intensity and frequency of gas flows from the seafloor. The SN-4 observatory was recently re-deployed in the same site for another one year mission (September 2013) in the framework of MARsite (New Directions in Seismic Hazard assessment through Focused Earth Observation in the Marmara Supersite) EC project which aims assessing the 'state of the art' of seismic risk evaluation and management at European level by long-term monitoring activities in Marmara Sea. References EMSO web site: http://www.emso-eu.org MARsite web site: http://www.marsite.eu/

  18. Using an Undergraduate Materials Research Project to Foster Multidisciplinary Teaming Skills

    ERIC Educational Resources Information Center

    Newell, James A.; Cleary, Doug D.

    2004-01-01

    This paper describes the use of undergraduate materials multidisciplinary research projects as a means of addressing the growing industrial demand for graduates experienced in working in multidisciplinary teams. It includes a detailed description of a project in which a multidisciplinary team of chemical engineering and civil engineering students…

  19. Challenges of Trainees in a Multidisciplinary Research Program: Nano-Biotechnology

    ERIC Educational Resources Information Center

    Kriegel, Christina; Koehne, Jessica; Tinkle, Sally; Maynard, Andrew D.; Hill, Rodney A.

    2011-01-01

    The breadth of knowledge required for the multidisciplinary field of nanotechnology challenges and extends traditional concepts of multidisciplinary graduate education. There is a paucity of information, both general reporting and peer-reviewed studies, on the challenges for graduate students working in this multidisciplinary paradigm, from the…

  20. SEMPATH Ontology: modeling multidisciplinary treatment schemes utilizing semantics.

    PubMed

    Alexandrou, Dimitrios Al; Pardalis, Konstantinos V; Bouras, Thanassis D; Karakitsos, Petros; Mentzas, Gregoris N

    2012-03-01

    A dramatic increase of demand for provided treatment quality has occurred during last decades. The main challenge to be confronted, so as to increase treatment quality, is the personalization of treatment, since each patient constitutes a unique case. Healthcare provision encloses a complex environment since healthcare provision organizations are highly multidisciplinary. In this paper, we present the conceptualization of the domain of clinical pathways (CP). The SEMPATH (SEMantic PATHways) Oontology comprises three main parts: 1) the CP part; 2) the business and finance part; and 3) the quality assurance part. Our implementation achieves the conceptualization of the multidisciplinary domain of healthcare provision, in order to be further utilized for the implementation of a Semantic Web Rules (SWRL rules) repository. Finally, SEMPATH Ontology is utilized for the definition of a set of SWRL rules for the human papillomavirus) disease and its treatment scheme. PMID:21768052

  1. Supporting multidisciplinary science within NASA's discipline data systems

    NASA Technical Reports Server (NTRS)

    Preheim, Larry E.

    1993-01-01

    Many current and future NASA and non-NASA missions are focusing on multidisciplinary science. The current paradigm for data identification and effective use by the NASA science community is based on the CODMAC model proposed in 1986. As multidisciplinary investigations become more prevalent, many existing systems and the newly developing systems will have to augment the current data identification and access strategies and tools and form alliances with other data systems to provide the broad range of data required. This paper describes the current paradigm, surveys and characterizes, within that paradigm, efforts to develop new access methods and data analysis and visualization tools, identifies additional areas of research not adequately addressed and recommends a further plan of action.

  2. Successful multidisciplinary treatment in an adolescent case of rumination.

    PubMed

    Cohen, Etti; Rosen, Yitzhak; Ben Yehuda, Yoram; Iancu, Iulian

    2004-01-01

    Rumination is a rare and complex disorder to treat. It involves repeated regurgitation, rechewing and reswallowing of food and occurs mainly among infants and mentally retarded children. Among adolescents and adults it is rather rare, but still might cause significant sequelae (depression, other eating disorders and social problems). We provide a detailed psychodynamic formulation in a non-retarded adolescent with rumination (over a four year period). A multidisciplinary approach involving individual insight-oriented psychotherapy, group therapy, pharmacological therapy and a nutritional intervention has proved successful in abating the patient's symptoms. We propose that among adolescents and adults, childhood issues of neglect and feeding problems may be reactivated through the rumination symptom. The focus of this report is to address the importance of rumination, as well as the role of a multidisciplinary approach to such cases. PMID:15754527

  3. Assessing and Evaluating Multidisciplinary Translational Teams: A Mixed Methods Approach

    PubMed Central

    Wooten, Kevin C.; Rose, Robert M.; Ostir, Glenn V.; Calhoun, William J.; Ameredes, Bill T.; Brasier, Allan R.

    2014-01-01

    A case report illustrates how multidisciplinary translational teams can be assessed using outcome, process, and developmental types of evaluation using a mixed methods approach. Types of evaluation appropriate for teams are considered in relation to relevant research questions and assessment methods. Logic models are applied to scientific projects and team development to inform choices between methods within a mixed methods design. Use of an expert panel is reviewed, culminating in consensus ratings of 11 multidisciplinary teams and a final evaluation within a team type taxonomy. Based on team maturation and scientific progress, teams were designated as: a) early in development, b) traditional, c) process focused, or d) exemplary. Lessons learned from data reduction, use of mixed methods, and use of expert panels are explored. PMID:24064432

  4. Breaking Down the Siloes: Developing Effective Multidisciplinary HIV Research Teams.

    PubMed

    Magnus, Manya; Castel, Amanda

    2016-09-01

    As the HIV epidemic passes its 35 years mark, the role of multidisciplinary approaches to HIV research has become increasingly important. Development of diverse, cross-cutting research teams has been found to be key to engaging and retaining participants in population-based studies; it is also a crucial component of designing studies capable of examining the sensitive and nuanced issues that surround HIV related risk and adherence behavior. Expanding our understanding of these issues is central to being able to overcome them and ultimately to the development of best practices for translation of research discovery into improvements in prevention and care. The objectives of this paper are to characterize the importance of multidisciplinary teams in HIV research where they are critical to gaining information that can have a positive impact on the epidemic and to propose specific methods for creating teams to conduct research with optimal public health impact. PMID:27435076

  5. ERS statement on the multidisciplinary respiratory management of ataxia telangiectasia.

    PubMed

    Bhatt, Jayesh M; Bush, Andrew; van Gerven, Marjo; Nissenkorn, Andreea; Renke, Michael; Yarlett, Lian; Taylor, Malcolm; Tonia, Thomy; Warris, Adilia; Zielen, Stefan; Zinna, Shairbanu; Merkus, Peter J F M

    2015-12-01

    Ataxia telangiectasia (A-T) is a rare, progressive, multisystem disease that has a large number of complex and diverse manifestations which vary with age. Patients with A-T die prematurely with the leading causes of death being respiratory diseases and cancer. Respiratory manifestations include immune dysfunction leading to recurrent upper and lower respiratory infections; aspiration resulting from dysfunctional swallowing due to neurodegenerative deficits; inefficient cough; and interstitial lung disease/pulmonary fibrosis. Malnutrition is a significant comorbidity. The increased radiosensitivity and increased risk of cancer should be borne in mind when requesting radiological investigations. Aggressive proactive monitoring and treatment of these various aspects of lung disease under multidisciplinary expertise in the experience of national multidisciplinary clinics internationally forms the basis of this statement on the management of lung disease in A-T. Neurological management is outwith the scope of this document. PMID:26621971

  6. Multidisciplinary therapy of extensive oligodontia: a case report.

    PubMed

    Gonçalves, Thaís Marques Simek Vega; Gonçalves, Letícia Machado; Sabino-Bezerra, José Ribamar; Santos-Silva, Alan Roger; da Silva, Wander José; Garcia, Renata Cunha Matheus Rodrigues

    2013-01-01

    Oligodontia is a rare congenital disorder consisting in the absence of six or more teeth. This case report describes a multidisciplinary treatment approach for a 12-year-old male with absence of 11 permanent teeth. Prior to any procedure, all primary teeth were scheduled for extraction due to poor crown-to-root ratio. The treatment plan comprised two phases: 1. orthodontic and speech therapy aimed at overbite and anterior open bite adjustment, as well as tongue position improvement; and 2. prosthetic treatment by insertion of removable temporary partial dentures. The multidisciplinary treatment involving orthodontics, speech and prosthetic therapies have reestablished the masticatory function and aesthetics, allowing the patient to achieve greater self-esteem and better social acceptance. PMID:23780360

  7. A Web-Based Monitoring System for Multidisciplinary Design Projects

    NASA Technical Reports Server (NTRS)

    Rogers, James L.; Salas, Andrea O.; Weston, Robert P.

    1998-01-01

    In today's competitive environment, both industry and government agencies are under pressure to reduce the time and cost of multidisciplinary design projects. New tools have been introduced to assist in this process by facilitating the integration of and communication among diverse disciplinary codes. One such tool, a framework for multidisciplinary computational environments, is defined as a hardware and software architecture that enables integration, execution, and communication among diverse disciplinary processes. An examination of current frameworks reveals weaknesses in various areas, such as sequencing, displaying, monitoring, and controlling the design process. The objective of this research is to explore how Web technology, integrated with an existing framework, can improve these areas of weakness. This paper describes a Web-based system that optimizes and controls the execution sequence of design processes; and monitors the project status and results. The three-stage evolution of the system with increasingly complex problems demonstrates the feasibility of this approach.

  8. A Multidisciplinary Research Agenda for Understanding Vaccine-Related Decisions.

    PubMed

    Larson, Heidi; Leask, Julie; Aggett, Sian; Sevdalis, Nick; Thomson, Angus

    2013-01-01

    There is increasingly broad global recognition of the need to better understand determinants of vaccine acceptance. Fifteen social science, communication, health, and medical professionals (the "Motors of Trust in Vaccination" (MOTIV) think tank) explored factors relating to vaccination decision-making as a step to building a multidisciplinary research agenda. One hundred and forty seven factors impacting decisions made by consumers, professionals, and policy makers on vaccine acceptance, delay, or refusal were identified and grouped into three major categories: cognition and decision-making; groups and social norms; and communication and engagement. These factors should help frame a multidisciplinary research agenda to build an evidence base on the determinants of vaccine acceptance to inform the development of interventions and vaccination policies. PMID:26344114

  9. Multidisciplinary Environments: A History of Engineering Framework Development

    NASA Technical Reports Server (NTRS)

    Padula, Sharon L.; Gillian, Ronnie E.

    2006-01-01

    This paper traces the history of engineering frameworks and their use by Multidisciplinary Design Optimization (MDO) practitioners. The approach is to reference papers that have been presented at one of the ten previous Multidisciplinary Analysis and Optimization (MA&O) conferences. By limiting the search to MA&O papers, the authors can (1) identify the key ideas that led to general purpose MDO frameworks and (2) uncover roadblocks that delayed the development of these ideas. The authors make no attempt to assign credit for revolutionary ideas or to assign blame for missed opportunities. Rather, the goal is to trace the various threads of computer architecture and software framework research and to observe how these threads contributed to the commercial framework products available today.

  10. Breast cancer in young women: special considerations in multidisciplinary care

    PubMed Central

    Reyna, Chantal; Lee, Marie Catherine

    2014-01-01

    Breast cancer is one of the most prevalent cancers in females, and 5%–7% of breast cancer cases occur in women under 40 years of age. Breast cancer in the young has gained increased attention with an attempt to improve diagnosis and prognosis. Young patients tend to have different epidemiology, presenting with later stages and more aggressive phenotypes. Diagnostic imaging is also more difficult in this age group. Multidisciplinary care generally encompasses surgeons, medical oncologists, radiation oncologists, radiologists, and social workers. Other special considerations include reconstruction options, fertility, genetics, and psychosocial issues. These concerns enlarge the already diverse multidisciplinary team to incorporate new expertise, such as reproductive specialists and genetic counselors. This review encompasses an overview of the current multimodal treatment regimens and the unique challenges in treating this special population. Integration of diagnosis, treatment, and quality of life issues should be addressed and understood by each member in the interdisciplinary team in order to optimize outcomes. PMID:25300196

  11. Integrating principles and multidisciplinary projects in design education

    NASA Technical Reports Server (NTRS)

    Nevill, Gale E., Jr.

    1992-01-01

    The critical need to improve engineering design education in the U.S. is presented and a number of actions to achieve that end are discussed. The importance of teaching undergraduates the latest methods and principles through the means of team design in multidisciplinary projects leading to a testable product is emphasized. Desirable training for design instructors is described and techniques for selecting and managing projects that teach effectively are discussed.

  12. NASA Aeronautics Multidisciplinary Analysis and Design Fellowship Program

    NASA Technical Reports Server (NTRS)

    Grossman, B.; Guerdal, Z.; Haftka, R. T.; Kapania, R. K.; Mason, W. H.; Mook, D. T.

    1998-01-01

    For a number of years, Virginia Tech had been on the forefront of research in the area of multidisciplinary analysis and design. In June of 1994, faculty members from aerospace and ocean engineering, engineering science and mechanics, mechanical engineering, industrial engineering, mathematics and computer sciences, at Virginia Tech joined together to form the Multidisciplinary Analysis and Design (MAD) Center for Advanced Vehicles. The center was established with the single goal: to perform research that is relevant to the needs of the US industry and to foster collaboration between the university, government and industry. In October of 1994, the center was chosen by NASA headquarters as one of the five university centers to establish a fellowship program to develop a graduate program in multidisciplinary analysis and design. The fellowship program provides full stipend and tuition support for seven U. S. students per year during their graduate studies. To advise us regarding the problems faced by the industry, an industrial advisory board has been formed consisting of representatives from industry as well as government laboratories. The function of the advisory board is to channel information from its member companies to faculty members concerning problems that need research attention in the general area of multidisciplinary design optimization (MDO). The faculty and their graduate students make proposals to the board on how to address these problems. At the annual board meeting in Blacksburg, the board discusses the proposals and suggests which students get funded under the NASA fellowship program. All students participating in the program are required to spend 3-6 months in industry working on their research projects. We are completing the third year of the fellowship program and have had three advisory board meetings in Blacksburg.

  13. Recent Experiences in Multidisciplinary Analysis and Optimization, part 2

    NASA Technical Reports Server (NTRS)

    Sobieski, J. (Compiler)

    1984-01-01

    The papers presented at the NASA Symposium on Recent Experiences in Multidisciplinary Analysis and Optimization held at NASA Langley Research Center, Hampton, Virginia, April 24 to 26, 1984 are given. The purposes of the symposium were to exchange information about the status of the application of optimization and the associated analyses in industry or research laboratories to real life problems and to examine the directions of future developments.

  14. Strengthening Multidisciplinary Research on Climate and Environmental Change

    NASA Astrophysics Data System (ADS)

    Beer, Tom; Li, Jianping; Alverson, Keith

    2014-08-01

    The difficulty with multidisciplinary research is finding common ground for scientists, whose approach to a particular scientific problem can differ radically. For example, there is agreement between the geophysical community and the food science and technology community that food security is an important issue. However, the climate change community sees possible solutions coming from more detailed studies on the links between climate change and agriculture, whereas the food science community sees possible solutions emerging from studies of food logistics and supply chains.

  15. Multidisciplinary management of multiple spinal dural arteriovenous fistulae

    PubMed Central

    Ge, Liang; Feng, Rui; Zhang, Xiaolong; Sun, Bing; Gu, Shixin; Xu, Qiwu; Lu, Gang; Huang, Lei

    2013-01-01

    Multiple SDAVFs are quite rare. We present two cases with double synchronous shunts and both were treated during one-stage interventional or surgical procedure. Unique images of the multiple SDAVFs as a PMAVF-like fistula were obtained. These interesting findings suggest the presence of multiple fistulas must be considered in patients being evaluated for SDAVF. A multidisciplinary approach to the management of multiple SDAVFs should depend on the anatomic location and angioarchitecture. PMID:24179577

  16. Importance of multidisciplinary approach in diagnosis of histoplasmosis*

    PubMed Central

    de Oliveira, Patricia Botini; de Abreu, Marilda Aparecida Milanez Morgado; Mattos, Antônio Luiz de Arruda

    2016-01-01

    A patient with systemic involvement, initially treated as tuberculosis, is presented in this report. There were only two painful subcutaneous nodules, from which we arrived at the correct diagnosis of histoplasmosis. The patient was attended by several experts in the fields of infectious diseases, nephrology and internal medicine, but the diagnosis was only possible after dermatological examination and skin biopsy. This case values multidisciplinary interaction between dermatologists and other medical areas for diagnosis of cases with atypical manifestations. PMID:27438207

  17. Importance of multidisciplinary approach in diagnosis of histoplasmosis.

    PubMed

    Oliveira, Patricia Botini de; Abreu, Marilda Aparecida Milanez Morgado de; Mattos, Antônio Luiz de Arruda

    2016-01-01

    A patient with systemic involvement, initially treated as tuberculosis, is presented in this report. There were only two painful subcutaneous nodules, from which we arrived at the correct diagnosis of histoplasmosis. The patient was attended by several experts in the fields of infectious diseases, nephrology and internal medicine, but the diagnosis was only possible after dermatological examination and skin biopsy. This case values multidisciplinary interaction between dermatologists and other medical areas for diagnosis of cases with atypical manifestations. PMID:27438207

  18. Evolution of a multidisciplinary cerebrovascular center: lessons learned.

    PubMed

    Hui, Ferdinand K; Spiotta, Alejandro M; Katzan, Irene; Manno, Edward M; Masaryk, Thomas J; Rasmussen, Peter A

    2012-03-01

    The Cerebrovascular Center at the Cleveland Clinic is an integrated, multidisciplinary center comprising vascular neurologists, neurointensivists, physiatrists, open and endovascular neurosurgeons, interventional neurologists and interventional neuroradiologists administered through a single financial center with unified governance and leadership. This report describes the history and evolution of the center from conceptualization to the present, as well as outlining lessons learned in the formation and maturation of the group. PMID:21990440

  19. Recent Advances in Multidisciplinary Analysis and Optimization, part 3

    NASA Technical Reports Server (NTRS)

    Barthelemy, Jean-Francois M. (Editor)

    1989-01-01

    This three-part document contains a collection of technical papers presented at the Second NASA/Air Force Symposium on Recent Advances in Multidisciplinary Analysis and Optimization, held September 28-30, 1988 in Hampton, Virginia. The topics covered include: aircraft design, aeroelastic tailoring, control of aeroelastic structures, dynamics and control of flexible structures, structural design, design of large engineering systems, application of artificial intelligence, shape optimization, software development and implementation, and sensitivity analysis.

  20. Recent Advances in Multidisciplinary Analysis and Optimization, part 1

    NASA Technical Reports Server (NTRS)

    Barthelemy, Jean-Francois M. (Editor)

    1989-01-01

    This three-part document contains a collection of technical papers presented at the Second NASA/Air Force Symposium on Recent Advances in Multidisciplinary Analysis and Optimization, held September 28-30, 1988 in Hampton, Virginia. The topics covered include: helicopter design, aeroelastic tailoring, control of aeroelastic structures, dynamics and control of flexible structures, structural design, design of large engineering systems, application of artificial intelligence, shape optimization, software development and implementation, and sensitivity analysis.

  1. Implementation of generalized optimality criteria in a multidisciplinary environment

    NASA Technical Reports Server (NTRS)

    Canfield, R. A.; Venkayya, V. B.

    1989-01-01

    A generalized optimality criterion method consisting of a dual problem solver combined with a compound scaling algorithm was implemented in the multidisciplinary design tool, ASTROS. This method enables, for the first time in a production design tool, the determination of a minimum weight design using thousands of independent structural design variables while simultaneously considering constraints on response quantities in several disciplines. Even for moderately large examples, the computational efficiency is improved significantly relative to the conventional approach.

  2. Recent Advances in Multidisciplinary Analysis and Optimization, part 2

    NASA Technical Reports Server (NTRS)

    Barthelemy, Jean-Francois M. (Editor)

    1989-01-01

    This three-part document contains a collection of technical papers presented at the Second NASA/Air Force Symposium on Recent Advances in Multidisciplinary Analysis and Optimization, held September 28-30, 1988 in Hampton, Virginia. The topics covered include: helicopter design, aeroelastic tailoring, control of aeroelastic structures, dynamics and control of flexible structures, structural design, design of large engineering systems, application of artificial intelligence, shape optimization, software development and implementation, and sensitivity analysis.

  3. Multidisciplinary Optimization Branch Experience Using iSIGHT Software

    NASA Technical Reports Server (NTRS)

    Padula, S. L.; Korte, J. J.; Dunn, H. J.; Salas, A. O.

    1999-01-01

    The Multidisciplinary Optimization (MDO) Branch at NASA Langley Research Center is investigating frameworks for supporting multidisciplinary analysis and optimization research. An optimization framework call improve the design process while reducing time and costs. A framework provides software and system services to integrate computational tasks and allows the researcher to concentrate more on the application and less on the programming details. A framework also provides a common working environment and a full range of optimization tools, and so increases the productivity of multidisciplinary research teams. Finally, a framework enables staff members to develop applications for use by disciplinary experts in other organizations. Since the release of version 4.0, the MDO Branch has gained experience with the iSIGHT framework developed by Engineous Software, Inc. This paper describes experiences with four aerospace applications: (1) reusable launch vehicle sizing, (2) aerospike nozzle design, (3) low-noise rotorcraft trajectories, and (4) acoustic liner design. All applications have been successfully tested using the iSIGHT framework, except for the aerospike nozzle problem, which is in progress. Brief overviews of each problem are provided. The problem descriptions include the number and type of disciplinary codes, as well as all estimate of the multidisciplinary analysis execution time. In addition, the optimization methods, objective functions, design variables, and design constraints are described for each problem. Discussions on the experience gained and lessons learned are provided for each problem. These discussions include the advantages and disadvantages of using the iSIGHT framework for each case as well as the ease of use of various advanced features. Potential areas of improvement are identified.

  4. Innovative multidisciplinary research in environmental epidemiology: the challenges and needs.

    PubMed

    Vena, J E; Weiner, J M

    1999-01-01

    The ability of epidemiology to determine the relationships between health and environmental insults has become exceedingly difficult. The multifactorial nature of disease and the diversity of the insults, which include biologic, physical, social and cultural factors, combined with genetic susceptibility, suggest the need to develop better models of multidisciplinary epidemiologic investigation. This paper highlights the needs of an environmental epidemiologic team, discusses ways to incorporate new ideas across disciplines and to integrate constructs and paradigms of social, ecological, cultural and population determinants with individual-based exposure assessments. Innovation will be the key to the survival and increasing importance of epidemiology in addressing the public health needs of the future, but what are the ways to enhance and encourage creativity in environmental epidemiology? The process of self-renewal and continuing education will be highlighted. Additionally, the complexity of the problems and the need for clear supervision and control of multidisciplinary research efforts require a forum of communication and an 'information-processing approach' beyond those in traditional epidemiologic studies. New approaches in data management and medical informatics must be incorporated into the epidemiologic investigative framework. Methods to be included should focus on opportunities for computer-supported sharing of ideas. Such capabilities minimise the geographic distances and the disparate knowledge and training of the investigators and bring the team closer to the objectives and functions inherent in multidisciplinary investigation. PMID:10703183

  5. Effective multidisciplinary working: the key to high-quality care.

    PubMed

    Ndoro, Samuel

    This article explores multidisciplinary team working, inter-disciplinary, trans-disciplinary and effective collaborative practice in order to provide high-quality patient care. It discusses different views on collaboration, some of the issues around cross-discipline and multi-agency working and concerns around promoting 'high-quality' care. It also discusses the importance of evidence-based practice in multidisciplinary teams. Issues around good-quality care, clinical governance and the audit cycle in MDTs are addressed. The article highlights the importance of the 6Cs (care, compassion, competence, communication, courage and commitment) in MDTs if quality care is to be achieved. The article also explores advantages and limitations of multidisciplinary team working, trans-disciplinary working and inter-professional working in developing and delivering high-quality patient-centred care. Further research is needed on how clinical audits can help to improve how MDTs function in order improve the quality of service provided to clients. PMID:25072333

  6. Multidisciplinary Optimization Branch Experience Using iSIGHT Software

    NASA Technical Reports Server (NTRS)

    Padula, S. L.; Korte, J. J.; Dunn, H. J.; Salas, A. O.

    1999-01-01

    The Multidisciplinary Optimization (MDO) Branch at NASA Langley is investigating frameworks for supporting multidisciplinary analysis and optimization research. A framework provides software and system services to integrate computational tasks and allows the researcher to concentrate more on the application and less on the programming details. A framework also provides a common working environment and a full range of optimization tools, and so increases the productivity of multidisciplinary research teams. Finally, a framework enables staff members to develop applications for use by disciplinary experts in other organizations. This year, the MDO Branch has gained experience with the iSIGHT framework. This paper describes experiences with four aerospace applications, including: (1) reusable launch vehicle sizing, (2) aerospike nozzle design, (3) low-noise rotorcraft trajectories, and (4) acoustic liner design. Brief overviews of each problem are provided, including the number and type of disciplinary codes and computation time estimates. In addition, the optimization methods, objective functions, design variables, and constraints are described for each problem. For each case, discussions on the advantages and disadvantages of using the iSIGHT framework are provided as well as notes on the ease of use of various advanced features and suggestions for areas of improvement.

  7. Multidisciplinary management of type 2 diabetes in children and adolescents.

    PubMed

    Bowen, Michael E; Rothman, Russell L

    2010-01-01

    Although once considered a disease of adults, the prevalence of type 2 diabetes in youth is increasing at a significant rate. Similar to adults, youth with type 2 diabetes are at increased risk for developing hypertension, lipid abnormalities, renal disease, and other diabetes-related complications. However, children and adolescents with type 2 diabetes also face many unique management challenges that are different from adults with type 2 diabetes or children with type 1 diabetes. To deliver safe, effective, high-quality, cost-effective health care to adolescents with type 2 diabetes, reorganization and redesign of health care systems are needed. Multidisciplinary health care teams, which allow individuals with specialized training to maximally utilize their skills within an organized diabetes treatment team, may increase efficiency and effectiveness and may improve outcomes in children with type 2 diabetes. This review article provides a brief review of type 2 diabetes in children and adolescents, provides an overview of multidisciplinary health care teams, and discusses the role of multidisciplinary health care management in youth with type 2 diabetes. PMID:21197360

  8. [Biobanks European infrastructure].

    PubMed

    Kinkorová, Judita; Topolčan, Ondřej

    2016-01-01

    Biobanks are structured repositories of human tissue samples connected with specific information. They became an integral part of personalized medicine in the new millennium. At the European research area biobanks are isolated not well coordinated and connected to the network. European commission supports European infrastructure BBMRI-ERIC (Biobanks and Biomolecular Resources Research Infrastructure European Research Infrastructure Consortium), consortium of 54 members with more than 225 associated organizations, largely biobanks from over 30 countries. The aim is to support biomedical research using stored samples. Czech Republic is a member of the consortium as a national node BBMRI_CZ, consisting of five partners. PMID:27256149

  9. Development from the seafloor to the sea surface of the cabled NEMO-SN1 observatory in the Western Ionian Sea

    NASA Astrophysics Data System (ADS)

    Sparnocchia, Stefania; Beranzoli, Laura; Borghini, Mireno; Durante, Sara; Favali, Paolo; Giovanetti, Gabriele; Italiano, Francesco; Marinaro, Giuditta; Meccia, Virna; Papaleo, Riccardo; Riccobene, Giorgio; Schroeder, Katrin

    2015-04-01

    A prototype of cabled deep-sea observatory has been operating in real-time since 2005 in Southern Italy (East Sicily, 37°30' N - 15°06'E), at 2100 m water depth, 25 km from the harbor of the city of Catania. It is the first-established real-time node of the "European Multidisciplinary Seafloor and water column Observatory" (EMSO, http://www.emso-eu.org) a research infrastructure of the Sector Environment of ESFRI. In the present configuration it consists of two components: the multi-parametric station NEMO-SN1 (TSN branch) equipped with geophysical and environmental sensors for measurements at the seafloor, and the NEMO-OνDE station (TSS branch) equipped with 4 wideband hydrophones. A 28 km long electro-optical cable connects the observatory to a shore laboratory in the Catania harbor, hosting the data acquisition system and supplying power and data transmission to the underwater instrumentation. The NEMO-SN1 observatory is located in an area particularly suited to multidisciplinary studies. The site is one of the most seismically active areas of the Mediterranean (some of the strongest earthquakes occurred in 1169, 1693 and 1908, also causing very intense tsunami waves) and is close to Mount Etna, one of the largest and most active volcanoes in Europe. The deployment area is also a key site for monitoring deep-water dynamics in the Ionian Sea, connecting the Levantine basin to the southern Adriatic basin where intermediate and deep waters are formed, and finally to the western Mediterranean Sea via the Strait of Sicily. The observatory is being further developed under EMSO MedIT (http://www.emso-medit.it/en/), a structural enhancement project contributing to the consolidation and enhancement of the European research infrastructure EMSO in Italian Convergence Regions. In this framework, a new Junction Box will be connected to the TSN branch and will provide wired and wireless (acoustic connections) for seafloor platforms and moorings. This will allow the

  10. Towards a multidisciplinary e-infrastructure for the Mediterranean Supersite Volcanoes (MED-SUV) project

    NASA Astrophysics Data System (ADS)

    Nativi, Stefano; Mathieu, Pierre Philippe; Cossu, Roberto; Santoto, Mattia; Martini, Marcello; Puglisi, Giuseppe

    2014-05-01

    The MED-SUV European project (http://med-suv.eu/) aims to design and implement a multidisciplinary infrastructure for the volcanic risk management life-cycle in southern Italy. The MED-SUV infrastructure will rely upon the improvements of the understanding of geophysical processes underlying the volcanic systems of Vesuvius / Campi Flegrei and Mt. Etna. It will also achieve the integration of existing components, such as monitoring systems and data bases, novel sensors for the measurements of volcanic parameters, and tools for data analysis and process modelling. This effort will contribute to GEOSS (Global Earth Observation System of Systems - http://www.earthobservations.org/geoss.shtml) as one the volcano Supersite recognized by GEO (Group on Earth Observation) -see http://supersites.earthobservations.org/. To achieve its goals, MED-SUV needs an advanced e-infrastructure allowing: (a) heterogeneous data and processing systems to provide and share their resources, and (b) supersite Users to run their workflows and generate significant products. This presentation discusses the general interoperability approach and architecture characterizing the MED-SUV e-infrastructure. The MED-SUV e-infrastructure considered the concepts and solutions adopted by the GEOSS Common Infrastructure (GCI). The architecture requirements and system technologies builds on the experience done by relevant European projects in the framework of GEOSS and ESFRI (e.g. EuroGEOSS, GENESI, GEOWOW). MED-SUV e-infrastructure adopts three-tiers approach distinguishing among: (a) local and distributed Data/Information Providers; (b) the MED-SUV Brokering framework for harmonization and interoperability; (c) the MED-SUV e-collaboration environment for the generation and publication of advanced products. MED-SUV e-infrastructure development considers interoperability with the other two FP7 supersite projects: MARSITE and FUTUREVOLC, as well as EPOS.

  11. European auxiliary propulsion, 1972

    NASA Technical Reports Server (NTRS)

    Holcomb, L. B.

    1972-01-01

    The chemical and electric auxiliary propulsion technology of the United Kingdom, France, and West Germany is discussed in detail, and the propulsion technology achievements of Italy, India, Japan, and Russia are reviewed. A comparison is presented of Shell 405 catalyst and a European spontaneous hydrazine catalyst called CNESRO I. Finally, conclusions are drawn regarding future trends in European auxiliary propulsion technology development.

  12. European Spallation Source and Neutron Science

    NASA Astrophysics Data System (ADS)

    Yeck, James

    2014-03-01

    International collaborations in large-scale scientific projects can link Sciences and Society. Following this goal, the European Spallation Source (ESS) is a multi-disciplinary research centre under design and construction in Lund, Sweden. This new facility is funded by a collaboration of 17 European countries. Scandinavia is providing 50 percent of the construction cost whilst the other member states are providing financial support mainly via in-kind contribution from institutes, laboratories or industries of the given countries. Scientists and engineers from 35 different countries are members of the workforce in Lund who participate in its design and construction. The ESS will enable new opportunities for researchers in fields of life sciences, energy, environmental technology, cultural heritage and fundamental physics by producing very high flux neutrons to study condensed matter physics, chemistry, biology, nuclear physics and materials science. The ESS will be up to 30 times brighter than today's leading facilities and neutron sources. A tungsten target and a 5 MW long pulse proton accelerator, composed mainly of superconducting Radio-Frequency components, are used to achieve these goals.

  13. Project of a Near-Real-Time Sismo-acoustic Submarine Station for offshore monitoring (NRTSSS)

    NASA Astrophysics Data System (ADS)

    D'Anna, G.; Calore, D.; Mangano, G.; D'Alessandro, A.; Favali, P.

    2011-12-01

    The INGV seismic network ensures reliable and continuous monitoring of the Italian territory. However, the peculiarity of the Italian peninsula, characterised by an intense offshore geodynamic and seismic activity, requires the extension of the seismic monitoring to the sea. The aim of this project is: - to identify bottleneck is related to the construction, installation and use of underwater seismic station; - to define the most appropriate and low-cost architecture to guarantee the minimum functionality required for a seismic station. In order to obtain reliable seafloor seismic signals integrated to land-based network, the requirements to be fulfill are: - an acceptable coupling with the seabed; - the orientation of the components with respect to the magnetic North and to the verticality; - the correct time stamp of the data; - the data transfer to the land for the integration. Currently, the optimal solution for offshore seismic station is a cable connection to power and real-time data transfer, like the case of Western Ionian Sea cabled observatory, one of the operative node of the EMSO research infrastructure (European Multidisciplinary Seafloor and water column Observatory, http://emso-eu.org). But in the Mediterranean many seismic areas are located a few tens-hundreds of miles from the coast and cabled solutions are not feasible essentially for economic reasons. For this kind of installations EMSO research infrastructure foresees no-cabled solution, that requires a surface buoy deployed in the vicinity seafloor modules.This project plans to develop a surface buoy equipped with autonomous power supply system to power also the seafloor platforms and two-way communication system enabling the data transfer through latest generation of broadband radio communication or satellite link (Fig. 1). All the components of the prototype system are described.

  14. Multidisciplinary in-hospital teams improve patient outcomes: A review

    PubMed Central

    Epstein, Nancy E.

    2014-01-01

    Background: The use of multidisciplinary in-hospital teams limits adverse events (AE), improves outcomes, and adds to patient and employee satisfaction. Methods: Acting like “well-oiled machines,” multidisciplinary in-hospital teams include “staff” from different levels of the treatment pyramid (e.g. staff including nurses’ aids, surgical technicians, nurses, anesthesiologists, attending physicians, and others). Their enhanced teamwork counters the “silo effect” by enhancing communication between the different levels of healthcare workers and thus reduces AE (e.g. morbidity/mortality) while improving patient and healthcare worker satisfaction. Results: Multiple articles across diverse disciplines incorporate a variety of concepts of “teamwork” for staff covering emergency rooms (ERs), hospital wards, intensive care units (ICUs), and most critically, operating rooms (ORs). Cohesive teamwork improved communication between different levels of healthcare workers, and limited adverse events, improved outcomes, decreased the length of stay (LOS), and yielded greater patient “staff” satisfaction. Conclusion: Within hospitals, delivering the best medical/surgical care is a “team sport.” The goals include: Maximizing patient safety (e.g. limiting AE) and satisfaction, decreasing the LOS, and increasing the quality of outcomes. Added benefits include optimizing healthcare workers’ performance, reducing hospital costs/complications, and increasing job satisfaction. This review should remind hospital administrators of the critical need to keep multidisciplinary teams together, so that they can continue to operate their “well-oiled machines” enhancing the quality/safety of patient care, while enabling “staff” to optimize their performance and enhance their job satisfaction. PMID:25289149

  15. Theoretical description of teaching-learning processes: a multidisciplinary approach.

    PubMed

    Bordogna, C M; Albano, E V

    2001-09-10

    A multidisciplinary approach based on concepts from sociology, educational psychology, statistical physics, and computational science is developed for the theoretical description of teaching-learning processes that take place in the classroom. The emerging model is consistent with well-established empirical results, such as the higher achievements reached working in collaborative groups and the influence of the structure of the group on the achievements of the individuals. Furthermore, another social learning process that takes place in massive interactions among individuals via the Internet is also investigated. PMID:11531550

  16. Integrated Care and the Evolution of the Multidisciplinary Team.

    PubMed

    Dobbins, Mary Iftner; Thomas, Sheila A; Melton, Stacy L Stokes; Lee, Stacy

    2016-06-01

    The primary care medical home continues to adapt by applying new research to population health approaches to care. With the discovery that life experiences trigger a chain of biologic events linked to chronic illnesses, the role of patient-centered multidisciplinary care teams becomes of paramount importance. Subsequently, mental health professionals are being incorporated into the primary care setting, using their skills in nontraditional models to customize care for each patient. This "integration" of primary care and unique mental health services engenders opportunity for enhanced clinical care, professional workforce development and support, more effective population health initiatives, and informed health care policy. PMID:27262000

  17. Acute intermittent porphyria associated with respiratory failure: a multidisciplinary approach.

    PubMed

    Menegueti, Mayra Gonçalves; Gil Cezar, Alkmim-Teixeira; Casarini, Karin Aparecida; Muniz Cordeiro, Kátia Simone; Basile-Filho, Anibal; Martins-Filho, Olindo Assis; Auxiliadora-Martins, Maria

    2011-01-01

    Despite being challenging, delivery of effective nursing care to patients with acute intermittent porphyria is a matter of utmost importance. In this paper, the diversity of symptoms and the difficult diagnosis of this condition are emphasized, and details concerning the treatment of this disorder in the intensive care unit are presented. We believe that acute intermittent porphyria should be borne in mind during performance of differential diagnosis of neurological, psychiatric, and gastroenterological disorders on patients whose routine investigation tests are normal, especially when precipitating factors exist. Intensive care measures and a multidisciplinary team approach are essential. PMID:21687623

  18. Conservative multidisciplinary management of placenta percreta following in vitro fertilization

    PubMed Central

    Hong, Seong Yun; Won, Hye-Sung; Lee, Pil Ryang; Kim, Ahm

    2013-01-01

    Placenta percreta is an extremely rare and the most severe form of placental invasion, that is associated with severe maternal morbidity and mortality. We report a case of nulliparous woman who underwent 10 cycles of in vitro fertilization (IVF) without any known risk factors. We conserved her uterus by spontaneous vaginal delivery, leaving the placenta in situ, pelvic arterial embolization, and primary resection of the remaining placental tissues. This case demonstrates that repetitive IVF is a possible risk factor for placental invasion, and that conservation of the uterus can be achieved in such cases using a multidisciplinary approach. PMID:24328001

  19. [Curative treatment for esophageal cancer: results of a multidisciplinary consensus].

    PubMed

    Allemann, Pierre; Mantziari, Styliani; Wagner, Dorothea; Digklia, Antonia; Ozsahin, Esat; De Bari, Berardino; Dorta, Gian; Godat, Sébastien; Montserrat, Fraga; Sempoux, Christine; Brunel, Christophe; Demartines, Nicolas; Schäfer, Markus

    2016-06-15

    The management of patients with resectable cancer of the esophagus or gastroesophageal junction is currently not standardized. A multi- disciplinary regional consensus has been developed and is presented in this article. The standard workup includes an upper endoscopy, ultrasonography and a CT-scan. For locally advanced tumors, surgery should be associated with either preoperative radiochemotherapy orperioperative chemotherapy after discussion in multidisciplinary tumor board. Before the operation, smoking and alcohol cessation is imperative and nutritional status should be optimized. Nowadays, surgery is well standardized and generally performed minimally invasive accesses. After surgery, clinical and oncological follow-up is necessary. PMID:27487620

  20. MDO can help resolve the designer's dilemma. [Multidisciplinary design optimization

    SciTech Connect

    Sobieszczanski-sobieski, Jaroslaw; Tulinius, J.R. Rockwell International Corp., El Segundo, CA )

    1991-09-01

    Multidisciplinary design optimization (MDO) is presented as a rapidly growing body of methods, algorithms, and techniques that will provide a quantum jump in the effectiveness and efficiency of the quantitative side of design, and will turn that side into an environment in which the qualitative side can thrive. MDO borrows from CAD/CAM for graphic visualization of geometrical and numerical data, data base technology, and in computer software and hardware. Expected benefits from this methodology are a rational, mathematically consistent approach to hypersonic aircraft designs, designs pushed closer to the optimum, and a design process either shortened or leaving time available for different concepts to be explored.

  1. [Global brain metastases management strategy: a multidisciplinary-based approach].

    PubMed

    Métellus, P; Tallet, A; Dhermain, F; Reyns, N; Carpentier, A; Spano, J-P; Azria, D; Noël, G; Barlési, F; Taillibert, S; Le Rhun, É

    2015-02-01

    Brain metastases management has evolved over the last fifteen years and may use varying strategies, including more or less aggressive treatments, sometimes combined, leading to an improvement in patient's survival and quality of life. The therapeutic decision is subject to a multidisciplinary analysis, taking into account established prognostic factors including patient's general condition, extracerebral disease status and clinical and radiological presentation of lesions. In this article, we propose a management strategy based on the state of current knowledge and available therapeutic resources. PMID:25649388

  2. Evaluation of Methods for Multidisciplinary Design Optimization (MDO). Phase 1

    NASA Technical Reports Server (NTRS)

    Kodiyalam, Srinivas

    1998-01-01

    The NASA Langley Multidisciplinary Design Optimization (MDO) method evaluation study seeks to arrive at a set of guidelines for using promising MDO methods by accumulating and analyzing computational data for such methods. The data are collected by conducting a series of reproducible experiments. This report documents all computational experiments conducted in Phase I of the study. This report is a companion to the paper titled Initial Results of an MDO Method Evaluation Study by N. M. Alexandrov and S. Kodiyalam (AIAA-98-4884).

  3. MDO can help resolve the designer's dilemma. [multidisciplinary design optimization

    NASA Technical Reports Server (NTRS)

    Sobieszczanski-Sobieski, Jaroslaw; Tulinius, Jan R.

    1991-01-01

    Multidisciplinary design optimization (MDO) is presented as a rapidly growing body of methods, algorithms, and techniques that will provide a quantum jump in the effectiveness and efficiency of the quantitative side of design, and will turn that side into an environment in which the qualitative side can thrive. MDO borrows from CAD/CAM for graphic visualization of geometrical and numerical data, data base technology, and in computer software and hardware. Expected benefits from this methodology are a rational, mathematically consistent approach to hypersonic aircraft designs, designs pushed closer to the optimum, and a design process either shortened or leaving time available for different concepts to be explored.

  4. Multidisciplinary approach to tumors of the pancreas and biliary tree.

    PubMed

    Brown, Kimberly M

    2009-02-01

    Tumors of the pancreas and biliary tree remain formidable challenges to patients and clinicians. These tumors elude early detection, rapidly spread locally and systemically, and frequently recur despite apparently complete resection. Cystic tumors of the pancreas, however, may represent a subset of patients who do not uniformly require aggressive resection, and a thoughtful, evidence-based approach to work-up allows for the rational application of surgical therapy. Increasing evidence supports treating patients who have pancreaticobiliary disease in a multidisciplinary setting. PMID:19186234

  5. Multidisciplinary team perspectives on older adult hoarding and mental illness.

    PubMed

    Koenig, Terry L; Leiste, Matthew R; Spano, Richard; Chapin, Rosemary K

    2013-01-01

    This qualitative study examined multidisciplinary team members' perspectives of their involvement in older adult hoarding cases. Fifteen informants, as representatives of four hoarding teams, described cases in which teams did or did not work well together. Specifically, informants described their (a) team characteristics, (b) awareness of hoarding as a mental health illness, (c) barriers to providing mental health services for older adults who hoard, and (d) components of successful teamwork within the team and with the older adult as hoarder. Implications include research to better guide interventions, team training to develop common perspectives, and policy development that supports mental health representation on teams and in-home mental health treatment. PMID:23289417

  6. Multidisciplinary management of nonfunctional neuroendocrine tumor of the pancreas

    PubMed Central

    Folkert, Ian W; Hernandez, Paul; Roses, Robert E

    2016-01-01

    Pancreatic neuroendocrine tumors (PNETs) are a rare and diverse group of tumors; nonfunctional (NF) PNETs account for the majority of cases. Most patients with NF-PNETs have metastatic disease at the time of presentation. A variety of treatment modalities exist, including medical, liver directed, and surgical treatments. Aggressive surgical management is associated with prolonged survival, however available data are limited by selection bias and the frequent combination of PNETs with carcinoid tumors. Although few patients with metastatic disease will be cured, application of currently available therapies in a multidisciplinary setting can lead to excellent outcomes with prolonged patient survival. PMID:27003988

  7. Acute Intermittent Porphyria Associated with Respiratory Failure: A Multidisciplinary Approach

    PubMed Central

    Menegueti, Mayra Gonçalves; Gil Cezar, Alkmim-Teixeira; Casarini, Karin Aparecida; Muniz Cordeiro, Kátia Simone; Basile-Filho, Anibal; Martins-Filho, Olindo Assis; Auxiliadora-Martins, Maria

    2011-01-01

    Despite being challenging, delivery of effective nursing care to patients with acute intermittent porphyria is a matter of utmost importance. In this paper, the diversity of symptoms and the difficult diagnosis of this condition are emphasized, and details concerning the treatment of this disorder in the intensive care unit are presented. We believe that acute intermittent porphyria should be borne in mind during performance of differential diagnosis of neurological, psychiatric, and gastroenterological disorders on patients whose routine investigation tests are normal, especially when precipitating factors exist. Intensive care measures and a multidisciplinary team approach are essential. PMID:21687623

  8. The successes and challenges of seven multidisciplinary teams.

    PubMed

    Twomey, Mary S; Jackson, Glenda; Li, Heidi; Marino, Theresa; Melchior, Lisa A; Randolph, John F; Retselli-Deits, Terri; Wysong, Julia

    2010-07-01

    The teams highlighted in this article represent a diversity of Multidisciplinary Teams (MDTs) but share similar challenges and successes. These shared experiences provide an opportunity to explore the key issues germane to MDTs. A hallmark of the elder abuse prevention community from its earliest days, the MDT has proven itself as a helpful and effective tool, one that will continue to add value to the field into the foreseeable future. These teams show that MDTs play a valuable role in helping communities increase collaboration, promoting efficiency in handling complex cases of elder abuse, educating the public, and ultimately safeguarding vulnerable adults from abuse. PMID:20711916

  9. The European Spallation Source

    NASA Astrophysics Data System (ADS)

    Lindroos, M.; Bousson, S.; Calaga, R.; Danared, H.; Devanz, G.; Duperrier, R.; Eguia, J.; Eshraqi, M.; Gammino, S.; Hahn, H.; Jansson, A.; Oyon, C.; Pape-Møller, S.; Peggs, S.; Ponton, A.; Rathsman, K.; Ruber, R.; Satogata, T.; Trahern, G.

    2011-12-01

    In 2003 the joint European effort to design a European Spallation Source (ESS) resulted in a set of reports, and in May 2009 Lund was agreed to be the ESS site. The ESS Scandinavia office has since then worked on setting all the necessary legal and organizational matters in place so that the Design Update and construction can be started in January 2011, in collaboration with European partners. The Design Update phase is expected to end in 2012, to be followed by a construction phase, with first neutrons expected in 2018-2019.

  10. Multidisciplinary intervention in obese adolescents: predictors of dropout

    PubMed Central

    Fidelix, Yara Lucy; de Farias, José Cazuza; Lofrano-Prado, Mara Cristina; Guerra, Ricardo Luís Fernandes; Cardel, Michelle; do Prado, Wagner Luiz

    2015-01-01

    Objective To identify biological and psychosocial factors associated with dropout in a multidisciplinary behavioral intervention in obese adolescents. Methods A total of 183 adolescents (15.4±1.6 years), pubertal (Tanner stage 3 or 4) and obese (34.7±4.0kg/m2), were enrolled in a 12-week behavioral intervention, which included clinical consultations (monthly), nutritional and psychological counseling (once a week), and supervised aerobic training (three times/week). The studied variables were weight, height, body mass index, body composition (skinfold), cardiorespiratory fitness (direct gas analysis), blood lipids and self-reported symptoms of eating disorders (bulimia, anorexia and binge eating), anxiety, depression, body image dissatisfaction and quality of life. Statistical analysis included binary logistic regression and independent t-tests. Results Of the adolescents, 73.7% adhered to the program. The greatest chance for dropout was observed among adolescents older than 15 years (odds ratio of 0.40; 95%CI: 0.15-0.98), with more anorexia symptoms (odds ratio of 0.35; 95%CI: 0.14-0.86) and hypercholesterolemia (odds ratio of 0.40; 95%CI: 0.16-0.91) at baseline. Conclusion Older adolescents, with more symptoms of eating disorders and total cholesterol have less chance to adhere to multidisciplinary treatments. PMID:26466062

  11. [Psychic changes in systemic lupus erythematosus: a multidisciplinary prospective study].

    PubMed

    Miguel Filho, E C; Pereira, R M; Busatto Filho, G; Shavitt, R G; Hirsch, R; de Sá, L C; de Arruda, P C

    1990-01-01

    Despite the high prevalence of psychic symptoms in lupus patients, there are few systematic studies in this area. Through a multidisciplinary approach, the authors developed a prospective study to characterize and correlate psychopathological aspects with clinical and laboratory data concerning neural manifestations of the disease. Out of 23 patients studied, 12 showed psychic alterations, which were interpreted as primary manifestations of the disease. All of them presented organic mental syndromes (DSM-III-R) in which cognitive symptoms were the most prominent, followed by affective, catatonic and hallucinatory features. The neurologic findings (seizure, migraine and muscular atrophy), as well as the ophthalmologic alterations (hemorrhage and soft exudates) were frequent and concomitant with the psychic features. The laboratory findings were: LE cells 50%; anti-Sm: 16%; anti-U1 RNP: 50%; anti-Ro/SS-A: 50%; anti-nDNA: 58%; decreased CH50 or fractions (C3, C4): 67%; anti-P: 18%; antigangliosides IgG: 67%; antigangliosides IgM: 78%. The cerebrospinal fluid analysis showed: increased cellularity: 18%; elevated protein: 36%; antigangliosides IgG: 67%; antigangliosides IgM: 33%; immunocomplexes: 36%. In spite of the absence of an adequate control group and of the small number of patients, the multidisciplinary approach leads to a better characterization of the nervous system involvement in this disease. PMID:1965671

  12. Development of a Multi-Disciplinary Computing Environment (MDICE)

    NASA Technical Reports Server (NTRS)

    Kingsley, Gerry; Siegel, John M., Jr.; Harrand, Vincent J.; Lawrence, Charles; Luker, Joel J.

    1999-01-01

    The growing need for and importance of multi-component and multi-disciplinary engineering analysis has been understood for many years. For many applications, loose (or semi-implicit) coupling is optimal, and allows the use of various legacy codes without requiring major modifications. For this purpose, CFDRC and NASA LeRC have developed a computational environment to enable coupling between various flow analysis codes at several levels of fidelity. This has been referred to as the Visual Computing Environment (VCE), and is being successfully applied to the analysis of several aircraft engine components. Recently, CFDRC and AFRL/VAAC (WL) have extended the framework and scope of VCE to enable complex multi-disciplinary simulations. The chosen initial focus is on aeroelastic aircraft applications. The developed software is referred to as MDICE-AE, an extensible system suitable for integration of several engineering analysis disciplines. This paper describes the methodology, basic architecture, chosen software technologies, salient library modules, and the current status of and plans for MDICE. A fluid-structure interaction application is described in a separate companion paper.

  13. New Approaches to HSCT Multidisciplinary Design and Optimization

    NASA Technical Reports Server (NTRS)

    Schrage, D. P.; Craig, J. I.; Fulton, R. E.; Mistree, F.

    1996-01-01

    The successful development of a capable and economically viable high speed civil transport (HSCT) is perhaps one of the most challenging tasks in aeronautics for the next two decades. At its heart it is fundamentally the design of a complex engineered system that has significant societal, environmental and political impacts. As such it presents a formidable challenge to all areas of aeronautics, and it is therefore a particularly appropriate subject for research in multidisciplinary design and optimization (MDO). In fact, it is starkly clear that without the availability of powerful and versatile multidisciplinary design, analysis and optimization methods, the design, construction and operation of im HSCT simply cannot be achieved. The present research project is focused on the development and evaluation of MDO methods that, while broader and more general in scope, are particularly appropriate to the HSCT design problem. The research aims to not only develop the basic methods but also to apply them to relevant examples from the NASA HSCT R&D effort. The research involves a three year effort aimed first at the HSCT MDO problem description, next the development of the problem, and finally a solution to a significant portion of the problem.

  14. The interplay of conflict and analogy in multidisciplinary teams.

    PubMed

    Paletz, Susannah B F; Schunn, Christian D; Kim, Kevin H

    2013-01-01

    Creative teamwork in multidisciplinary teams is a topic of interest to cognitive psychologists on the one hand, and to both social and organizational psychologists on the other. However, the interconnections between cognitive and social layers have been rarely explored. Drawing on mental models and dissonance theories, the current study takes a central variable studied by cognitive psychologists-analogy-and examines its relationship to a central variable examined by social psychologists-conflict. In an observational, field study, over 11h of audio-video data from conversations of the Mars Exploration Rover scientists were coded for different types of analogy and micro-conflicts that reveal the character of underlying psychological mechanisms. Two different types of time-lagged logistic models applied to these data revealed asymmetric patterns of associations between analogy and conflict. Within-domain analogies, but not within-discipline or outside-discipline analogies, preceded science and work process conflicts, suggesting that in multidisciplinary teams, representational gaps in very close domains will be more likely to spark conflict. But analogies also occurred in reaction to conflict: Process and negative conflicts, but not task conflicts, preceded within-discipline analogies, but not to within-domain or outside-discipline analogies. This study demonstrates ways in which cognition can be bidirectionally tied to social processes and discourse. PMID:22980920

  15. What is a virtual multidisciplinary team (vMDT)?

    PubMed Central

    Munro, A J; Swartzman, S

    2013-01-01

    Background: Multidisciplinary team meetings (MDTs), also known as tumour boards or multidisciplinary case conferences, are an integral component of contemporary cancer care. There are logistical problems with setting up and maintaining participation in these meetings. An ill-defined concept, the virtual MDT (vMDT), has arisen in response to these difficulties. We have, in order to provide clarity and to generate discussion, attempted to define the concept of the vMDT, outline its advantages and disadvantages, and consider some of the practical aspects involved in setting up a virtual MDT. Methods: This is an unstructured review of published evidence and personal experience relating to virtual teams in general, and to MDTs in particular. Results: We have devised a simple taxonomy for MDTs, discussed some of the practicalities involved in setting up a vMDT, and described some of the potential advantages and disadvantages associated with vMDTs. Conclusion: The vMDT may be useful for discussions concerning rare or unusual tumours, or for helping guide the assessment and management of patients with uncommon complications related to treatment. However, the vMDT is a niche concept and is currently unlikely to replace the more traditional face-to-face MDT in the management of common tumours at specific sites. PMID:23756866

  16. New Approaches to HSCT Multidisciplinary Design and Optimization

    NASA Technical Reports Server (NTRS)

    Schrage, Daniel P.; Craig, James I.; Fulton, Robert E.; Mistree, Farrokh

    1999-01-01

    New approaches to MDO have been developed and demonstrated during this project on a particularly challenging aeronautics problem- HSCT Aeroelastic Wing Design. To tackle this problem required the integration of resources and collaboration from three Georgia Tech laboratories: ASDL, SDL, and PPRL, along with close coordination and participation from industry. Its success can also be contributed to the close interaction and involvement of fellows from the NASA Multidisciplinary Analysis and Optimization (MAO) program, which was going on in parallel, and provided additional resources to work the very complex, multidisciplinary problem, along with the methods being developed. The development of the Integrated Design Engineering Simulator (IDES) and its initial demonstration is a necessary first step in transitioning the methods and tools developed to larger industrial sized problems of interest. It also provides a framework for the implementation and demonstration of the methodology. Attachment: Appendix A - List of publications. Appendix B - Year 1 report. Appendix C - Year 2 report. Appendix D - Year 3 report. Appendix E - accompanying CDROM.

  17. Multidisciplinary perspective of hepatocellular carcinoma: A Pacific Northwest experience

    PubMed Central

    Yeh, Matthew M; Yeung, Raymond S; Apisarnthanarax, Smith; Bhattacharya, Renuka; Cuevas, Carlos; Harris, William P; Hon, Tony Lim Kiat; Padia, Siddharth A; Park, James O; Riggle, Kevin M; Daoud, Sayed S

    2015-01-01

    Hepatocellular carcinoma (HCC) is the most rapidly increasing type of cancer in the United States. HCC is a highly malignant cancer, accounting for at least 14000 deaths in the United States annually, and it ranks third as a cause of cancer mortality in men. One major difficulty is that most patients with HCC are diagnosed when the disease is already at an advanced stage, and the cancer cannot be surgically removed. Furthermore, because almost all patients have cirrhosis, neither chemotherapy nor major resections are well tolerated. Clearly there is need of a multidisciplinary approach for the management of HCC. For example, there is a need for better understanding of the fundamental etiologic mechanisms that are involved in hepatocarcinogenesis, which could lead to the development of successful preventive and therapeutic modalities. It is also essential to define the cellular and molecular bases for malignant transformation of hepatocytes. Such knowledge would: (1) greatly facilitate the identification of patients at risk; (2) prompt efforts to decrease risk factors; and (3) improve surveillance and early diagnosis through diagnostic imaging modalities. Possible benefits extend also to the clinical management of this disease. Because there are many factors involved in pathogenesis of HCC, this paper reviews a multidisciplinary perspective of recent advances in basic and clinical understanding of HCC that include: molecular hepatocarcinogenesis, non-invasive diagnostics modalities, diagnostic pathology, surgical modality, transplantation, local therapy and oncological/target therapeutics. PMID:26085907

  18. Menkes disease: what a multidisciplinary approach can do

    PubMed Central

    Ojha, Rahul; Prasad, Asuri N

    2016-01-01

    Disorders of copper homeostasis are currently recognized across the life span. Their recognition and links to human disease have spanned several decades, beginning with the recognition of a degenerative disorder in the offspring of sheep grazing in copper-deficient pastures, through to the description of infants suffering from a progressive neurodegenerative disorder characterized by epileptic seizures, developmental regression, failure to thrive, and an unusual hair quality (giving the condition its distinctive label of “kinky hair disease”). In this review, we trace the historical background and describe the biochemistry and physiology of copper metabolism and transport, inheritance patterns, molecular genetics, and genotype–phenotype correlations based on current understanding of the disorder. It is clear from the clinical presentations and variants that disorders of copper homeostasis include phenotypes ranging from mild occipital horn syndrome to intermediate and severe forms of classical Menkes disease. The symptoms involve multiple organ systems such as brain, lung, gastrointestinal tract, urinary tract, connective tissue, and skin. A multisystem disorder needs a multidisciplinary approach to care, as treatment interventions permit longer survival for some individuals. Animal models have been developed to help screen treatment options and provide a better understanding of these disorders in the laboratory. Finally, we propose a multidisciplinary approach to promote continued research (both basic and clinical) to improve survival, quality of life, and care for these conditions. PMID:27574440

  19. Bioenergy research: a new paradigm in multidisciplinary research

    PubMed Central

    Kalluri, Udaya C.; Keller, Martin

    2010-01-01

    The field of biology is becoming increasingly interdisciplinary and cross-cutting. This changing research atmosphere is creating the way for a new kind of enquiry that while building upon the traditional research establishment is providing a new multidisciplinary framework to more effectively address scientific grand challenges. Using the US Department of Energy sponsored BioEnergy Science Center as an example, we highlight how impactful breakthroughs in biofuel science can be achieved within a large cross-disciplinary team environment. Such transformational insights are key to furthering our understanding and in generating models, theories and processes that can be used to overcome recalcitrance of biomass for sustainable biofuel production. Multidisciplinary approaches have an increasingly greater role to play in meeting rising demands for food, fibre, energy, clean environment and good health. Discoveries achieved by diverse minds and cross-applications of tools and analytical approaches have tremendous potential to fill existing knowledge gaps, clear roadblocks and facilitate translation of basic sciences discoveries as solutions towards addressing some of the most pressing global issues. PMID:20542958

  20. Multidisciplinary Aerodynamic-Structural Shape Optimization Using Deformation (MASSOUD)

    NASA Technical Reports Server (NTRS)

    Samareh, Jamshid A.

    2000-01-01

    This paper presents a multidisciplinary shape parameterization approach. The approach consists of two basic concepts: (1) parameterizing the shape perturbations rather than the geometry itself and (2) performing the shape deformation by means of the soft object animation algorithms used in computer graphics. Because the formulation presented in this paper is independent of grid topology, we can treat computational fluid dynamics and finite element grids in the same manner. The proposed approach is simple, compact, and efficient. Also, the analytical sensitivity derivatives are easily computed for use in a gradient-based optimization. This algorithm is suitable for low-fidelity (e.g., linear aerodynamics and equivalent laminate plate structures) and high-fidelity (e.g., nonlinear computational fluid dynamics and detailed finite element modeling) analysis tools. This paper contains the implementation details of parameterizing for planform, twist, dihedral, thickness, camber, and free-form surface. Results are presented for a multidisciplinary application consisting of nonlinear computational fluid dynamics, detailed computational structural mechanics, and a simple performance module.

  1. An aggressive multidisciplinary approach reduces mortality in rhinocerebral mucormycosis

    PubMed Central

    Palejwala, Sheri K.; Zangeneh, Tirdad T.; Goldstein, Stephen A.; Lemole, G. Michael

    2016-01-01

    Background: Rhinocerebral mucormycosis occurs in immunocompromised hosts with uncontrolled diabetes, solid organ transplants, and hematologic malignancies. Primary disease is in the paranasal sinuses but often progresses intracranially, via direct extension or angioinvasion. Rhinocerebral mucormycosis is rapidly fatal with a mortality rate of 85%, even when maximally treated with surgical debridement, antifungal therapy, and correction of underlying processes. Methods: We performed a retrospective chart review of patients with rhinocerebral mucormycosis from 2011 to 2014. These patients were analyzed for symptoms, surgical and medical management, and outcome. We found four patients who were diagnosed with rhinocerebral mucormycosis. All patients underwent rapid aggressive surgical debridement and were started on antifungal therapy on the day of diagnosis. Overall, we observed a mortality rate of 50%. Results: An early aggressive multidisciplinary approach with surgical debridement, antifungal therapy, and correction of underlying disease have been shown to improve survivability in rhinocerebral mucormycosis. Conclusion: A multidisciplinary approach to rhinocerebral mucormycosis with otolaryngology, neurosurgery, and ophthalmology, infectious disease and medical intensivists can help reduce mortality in an otherwise largely fatal disease. Even despite these measures, outcomes remain poor, and a high index of suspicion must be maintained in at-risk populations, in order to rapidly execute a multifaceted approach. PMID:27280057

  2. Hormonal Contraception and Thrombotic Risk: A Multidisciplinary Approach

    PubMed Central

    Chung, Richard J.; Michelson, Alan D.; Neufeld, Ellis J.; Gordon, Catherine M.; Laufer, Marc R.; Emans, S. Jean

    2011-01-01

    Heightened publicity about hormonal contraception and thrombosis risk and the publication of new guidelines by the World Health Organization in 2009 and the Centers for Disease Control and Prevention in 2010 addressing this complex issue have led to multidisciplinary discussions on the special issues of adolescents cared for at our pediatric hospital. In this review of the literature and new guidelines, we have outlined our approach to the complex patients referred to our center. The relative risk of thrombosis on combined oral contraception is three- to fivefold, whereas the absolute risk for a healthy adolescent on this therapy is only 0.05% per year. This thrombotic risk is affected by estrogen dose, type of progestin, mechanism of delivery, and length of therapy. Oral progestin-only contraceptives and transdermal estradiol used for hormone replacement carry minimal or no thrombotic risk. Transdermal, vaginal, or intrauterine contraceptives and injectable progestins need further study. A personal history of thrombosis, persistent or inherited thrombophilia, and numerous lifestyle choices also influence thrombotic risk. In this summary of one hospital's approach to hormone therapies and thrombosis risk, we review relative-risk data and discuss the application of absolute risk to individual patient counseling. We outline our approach to challenging patients with a history of thrombosis, known thrombophilia, current anticoagulation, or family history of thrombosis or thrombophilia. Our multidisciplinary group has found that knowledge of the guidelines and individualized management plans have been particularly useful for informing discussions about hormonal and nonhormonal options across varied indications. PMID:21199853

  3. Menkes disease: what a multidisciplinary approach can do.

    PubMed

    Ojha, Rahul; Prasad, Asuri N

    2016-01-01

    Disorders of copper homeostasis are currently recognized across the life span. Their recognition and links to human disease have spanned several decades, beginning with the recognition of a degenerative disorder in the offspring of sheep grazing in copper-deficient pastures, through to the description of infants suffering from a progressive neurodegenerative disorder characterized by epileptic seizures, developmental regression, failure to thrive, and an unusual hair quality (giving the condition its distinctive label of "kinky hair disease"). In this review, we trace the historical background and describe the biochemistry and physiology of copper metabolism and transport, inheritance patterns, molecular genetics, and genotype-phenotype correlations based on current understanding of the disorder. It is clear from the clinical presentations and variants that disorders of copper homeostasis include phenotypes ranging from mild occipital horn syndrome to intermediate and severe forms of classical Menkes disease. The symptoms involve multiple organ systems such as brain, lung, gastrointestinal tract, urinary tract, connective tissue, and skin. A multisystem disorder needs a multidisciplinary approach to care, as treatment interventions permit longer survival for some individuals. Animal models have been developed to help screen treatment options and provide a better understanding of these disorders in the laboratory. Finally, we propose a multidisciplinary approach to promote continued research (both basic and clinical) to improve survival, quality of life, and care for these conditions. PMID:27574440

  4. Multidisciplinary Multiobjective Optimal Design for Turbomachinery Using Evolutionary Algorithm

    NASA Technical Reports Server (NTRS)

    2005-01-01

    This report summarizes Dr. Lian s efforts toward developing a robust and efficient tool for multidisciplinary and multi-objective optimal design for turbomachinery using evolutionary algorithms. This work consisted of two stages. The first stage (from July 2003 to June 2004) Dr. Lian focused on building essential capabilities required for the project. More specifically, Dr. Lian worked on two subjects: an enhanced genetic algorithm (GA) and an integrated optimization system with a GA and a surrogate model. The second stage (from July 2004 to February 2005) Dr. Lian formulated aerodynamic optimization and structural optimization into a multi-objective optimization problem and performed multidisciplinary and multi-objective optimizations on a transonic compressor blade based on the proposed model. Dr. Lian s numerical results showed that the proposed approach can effectively reduce the blade weight and increase the stage pressure ratio in an efficient manner. In addition, the new design was structurally safer than the original design. Five conference papers and three journal papers were published on this topic by Dr. Lian.

  5. Multifidelity, multidisciplinary optimization of turbomachines with shock interaction

    NASA Astrophysics Data System (ADS)

    Joly, Michael Marie

    Research on high-speed air-breathing propulsion aims at developing aircraft with antipodal range and space access. Before reaching high speed at high altitude, the flight vehicle needs to accelerate from takeoff to scramjet takeover. Air turbo rocket engines combine turbojet and rocket engine cycles to provide the necessary thrust in the so-called low-speed regime. Challenges related to turbomachinery components are multidisciplinary, since both the high compression ratio compressor and the powering high-pressure turbine operate in the transonic regime in compact environments with strong shock interactions. Besides, lightweight is vital to avoid hindering the scramjet operation. Recent progress in evolutionary computing provides aerospace engineers with robust and efficient optimization algorithms to address concurrent objectives. The present work investigates Multidisciplinary Design Optimization (MDO) of innovative transonic turbomachinery components. Inter-stage aerodynamic shock interaction in turbomachines are known to generate high-cycle fatigue on the rotor blades compromising their structural integrity. A soft-computing strategy is proposed to mitigate the vane downstream distortion, and shown to successfully attenuate the unsteady forcing on the rotor of a high-pressure turbine. Counter-rotation offers promising prospects to reduce the weight of the machine, with fewer stages and increased load per row. An integrated approach based on increasing level of fidelity and aero-structural coupling is then presented and allows achieving a highly loaded compact counter-rotating compressor.

  6. Multidisciplinary Management of Hepatocellular Carcinoma in Clinical Practice

    PubMed Central

    Cannita, Katia; Giordano, Aldo Victor; Manetta, Rosa; Vicentini, Roberto; Carducci, Sergio; Saltarelli, Patrizia; Iapadre, Nerio; Coletti, Gino; Ficorella, Corrado; Ricevuto, Enrico

    2014-01-01

    Background. Hepatocellular carcinoma (HCC) patients require different treatment strategies according to disease extension, liver function, and patient's fitness. We evaluated HCC multidisciplinary management in clinical practice. Methods. Consecutive patients were followed and treated with tailored medical, locoregional, and surgical treatments, according to disease stage and patient's fitness (age, Cumulative Illness Rating Scale (CIRS)). Activity, efficacy, and safety were evaluated. Results. Thirty-eight patients were evaluated: median age, 74; elderly 92%; CIRS secondary 28 (74%); Child-Pugh A 20 (53%), B 11 (29%); and Barcelona Clinic Liver Cancer (BCLC) 0 2 (5%), A 9 (24%), B 10 (26%), C 13 (34%), and D 4 (11%). Overall survival (OS) was 30 months. At 9 months median follow-up, among 25 unresectable HCC, OS was 10 months; BCLC B–D unfit for sorafenib showed OS 3 months. Ten patients (40%) received sorafenib: Child-Pugh A 5 (50%) and B 5 (50%) and disease control rate 89%, progression-free survival 7 months, and OS 9 months. G3-4 toxicities: anorexia, hypertransaminaemia, hyperbilirubinemia, and hypercreatininemia. Limiting toxicity syndromes were 40%, all multiple sites. Conclusion. HCC patients require multidisciplinary clinical management to properly select tailored treatments according to disease stage, fitness, and liver function. Patients suitable for sorafenib should be carefully selected, monitored for individual safety, and prevalently characterized by limiting toxicity syndromes multiple sites. PMID:24900987

  7. A relational conceptual framework for multidisciplinary health research centre infrastructure

    PubMed Central

    2010-01-01

    Although multidisciplinary and team-based approaches are increasingly acknowledged as necessary to address some of the most pressing contemporary health challenges, many researchers struggle with a lack of infrastructure to facilitate and formalise the requisite collaborations. Specialised research centres have emerged as an important organisational solution, yet centre productivity and sustainability are frequently dictated by the availability and security of infrastructure funds. Despite being widely cited as a core component of research capacity building, infrastructure as a discrete concept has been rather analytically neglected, often treated as an implicit feature of research environments with little specification or relegated to a narrow category of physical or administrative inputs. The terms research infrastructure, capacity, and culture, among others, are deployed in overlapping and inconsistent ways, further obfuscating the crucial functions of infrastructure specifically and its relationships with associated concepts. The case is made for an expanded conceptualisation of research infrastructure, one that moves beyond conventional 'hardware' notions. Drawing on a case analysis of NEXUS, a multidisciplinary health research centre based at the University of British Columbia, Canada, a conceptual framework is proposed that integrates the tangible and intangible structures that interactively underlie research centre functioning. A relational approach holds potential to allow for more comprehensive accounting of the returns on infrastructure investment. For those developing new research centres or seeking to reinvigorate existing ones, this framework may be a useful guide for both centre design and evaluation. PMID:20925953

  8. Progress in multidisciplinary sensing of the 4-dimensional ocean

    NASA Astrophysics Data System (ADS)

    Dickey, Tommy

    2009-05-01

    Many luminaries of oceanography have articulated the problem of adequately sampling a multiplicity of interdisciplinary ocean processes. Progress has accelerated within the past two decades as societal and naval interests in monitoring and predicting the state of the ocean environment has heightened. Oceanographers are capitalizing on a host of new platform and sensing technologies. Some recent programs contributing to improved 4-dimensional open and coastal ocean multi-disciplinary observations are used to highlight the development of new integrated optical, chemical, and physical measurement systems that can be deployed from stationary and mobile platforms to telemeter data in near real-time or real-time. For example, the NOPP O-SCOPE and MOSEAN projects have developed and tested several optical and chemical sensors in deep waters off Bermuda and Hawaii, at OWS 'P' in the North Pacific Ocean, and in coastal waters off Santa Barbara and Monterey, California. Most of the testing for these projects has been conducted using moorings; however, NOPP instrumentation is also being used on mobile platforms including AUVs, profiling floats, and gliders. Progress in adequately sampling the temporal and spatial variability of selected ocean 'sampling volumes' using multi-platform, multi-disciplinary sampling is described using examples from selected recent programs.

  9. Multidisciplinary management--an opportunity for service integration.

    PubMed

    Cameron, M

    1997-01-01

    The management team of the future will enter an environment requiring facilitation, participation, clinical, and empowerment skills. Those individuals who possess a clinical orientation as well as business expertise will be sought to manage multidisciplinary units. The rapid changes in the health-care environment have forced organizations to restructure their operations. To achieve quality care, customer satisfaction, cost-effectiveness, and efficiency, service integration across the organization will be required. As we approach the 21st century, this standard will evolve until "all levels are managing patient care." Some of the restructuring trends occurring in the health-care industry have been collaboration service integration, management consolidation, and job elimination. The emphasis for the multidisciplinary manager of the future will include integrating the professional and clinical services, managing information, building community partnerships, promoting physician collaboration, and managing the change process. A model organization in the next century will move toward a people-oriented system with inclusion and empowerment initiatives. Service integration will affect all organizations, but the disciplines within the Clinical Support System will be the most affected. Future opportunities of leadership will exist for pathologists, nurses, or medical technologists as the professional silos of managers and clinicians continue to crumble. PMID:10175172

  10. Surgical therapy in transsexual patients: a multi-disciplinary approach.

    PubMed

    Monstrey, S; Hoebeke, P; Dhont, M; De Cuypere, G; Rubens, R; Moerman, M; Hamdi, M; Van Landuyt, K; Blondeel, P

    2001-01-01

    A transsexual patient has the constant and persistent conviction that he or she belongs to the opposite sex, thus creating a deeply seated gender identity conflict. With psychotherapy being unsuccessful, it has been proven that in carefully selected patients, gender reassignment or adjusting the body to the mind (both with hormones and surgery) is the best way to normalize their lives. Optimal treatment of these patients requires the multidisciplinary approach of a gender team with the input of several specialties. Such a team consists of a nucleus of physicians who sees the patient more frequently: the psychiatrist, the endocrinologist, the plastic surgeon, the gynecologist and the urologist and a more peripheral group that sees the patients more incidentally: the psychologist, the otorhinolaryngologist, the dermatologist, the speech therapist, the lawyer, the nurse and the social worker. Between 1987 and 1999, a total of 71 male-to-female (MTF) and 54 female-to-male transsexuals have undergone gender confirming surgery in our hospital. This article gives a review and an update on the different surgical procedures as well as on the outcome in our patient population. The results in this series of patients clearly demonstrate that a close cooperation of the different surgical specialties, within our multidisciplinary gender team, is the key to success in treating transsexual patients. PMID:11758101

  11. A Multidisciplinary Approach to Mixer-Ejector Analysis and Design

    NASA Technical Reports Server (NTRS)

    Hendricks, Eric, S.; Seidel, Jonathan, A.

    2012-01-01

    The design of an engine for a civil supersonic aircraft presents a difficult multidisciplinary problem to propulsion system engineers. There are numerous competing requirements for the engine, such as to be efficient during cruise while yet quiet enough at takeoff to meet airport noise regulations. The use of mixer-ejector nozzles presents one possible solution to this challenge. However, designing a mixer-ejector which will successfully address both of these concerns is a difficult proposition. Presented in this paper is an integrated multidisciplinary approach to the analysis and design of these systems. A process that uses several low-fidelity tools to evaluate both the performance and acoustics of mixer-ejectors nozzles is described. This process is further expanded to include system-level modeling of engines and aircraft to determine the effects on mission performance and noise near airports. The overall process is developed in the OpenMDAO framework currently being developed by NASA. From the developed process, sample results are given for a notional mixer-ejector design, thereby demonstrating the capabilities of the method.

  12. [Tourette syndrome: from a neurological clinic to a multidisciplinary approach].

    PubMed

    Benarroch, Fortu; Warman, Orly; Gross-Tsur, Varda

    2006-04-01

    Tourette Syndrome (TS) is a chronic, familial disorder, characterized by involuntary motor and phonic tics that wax and wane in severity. TS is frequently accompanied by behavioral, emotional and cognitive problems that are often more incapacitating than the tic disorder itself. After a review of the disorder, in which the multidisciplinary aspects are emphasized, the article describes the clinical features of 60 children with TS, 49 boys and 11 girls, aged 13 +/- 3.6 years (mean SD), treated in the Neuropediatric Unit at Shaare Zedek Medical Center. The children described had both motor and vocal tics, but also had ADHD (n = 44), obsessive-compulsive disorder (n = 32), learning disabilities (with 12 children learning in special education frameworks) and behavioral disorders (n = 36). The clinical profile of this group of children with TS is similar to that reported on referred patients regardless of cultural background. Since children with TS manifest multiple comorbidities, optimal therapy mandates the cooperation of a multidisciplinary team including a pediatric neurologist, a child psychiatrist, a psychologist and a family therapist. Working in concert, these specialists can implement a multimodal approach, addressing the neurological and psychiatric aspects of TS as well as enhancing the child's coping skills with the disorder itself and its consequences. PMID:16642633

  13. Assessing multi-disciplinary Earth observation impacts on societal benefits

    NASA Astrophysics Data System (ADS)

    Pearlman, J.

    2011-12-01

    Multi-disciplinary interactions are becoming more important as demands for science-driven information needed for decision-making are increasing. Further development of systems to improve the scientific understanding of Earth's system and its response to natural or human-induced changes are required to meet this need. These would facilitate modeling and analyses in many critical areas such as climate prediction, food security, water availability and ecosystem sustainability among others. It is intuitive that better information will have a positive impact on decision outcomes. Yet this is difficult to quantitate. The impacts of multi-disciplinary work are particularly difficult to assess, yet it is hard to predict climate change without considering oceans, land use and many other Earth system characteristics. There are several steps that are important to quantitate the benefits. Some of these have been discussed at IIASA, RFI and other centers of excellence in this area. The key is to establish a program with metrics, a community of practice to propagate the metrics and clear case studies that will demonstrate effectiveness. A workshop was held to set the foundations for this approach and recommendations from a team of global experts are evolving into a program. This presentation discusses the indicators and metrics, examines their efficacy and looks at a case study to assess and validate the development.

  14. A relational conceptual framework for multidisciplinary health research centre infrastructure.

    PubMed

    Coen, Stephanie E; Bottorff, Joan L; Johnson, Joy L; Ratner, Pamela A

    2010-01-01

    Although multidisciplinary and team-based approaches are increasingly acknowledged as necessary to address some of the most pressing contemporary health challenges, many researchers struggle with a lack of infrastructure to facilitate and formalise the requisite collaborations. Specialised research centres have emerged as an important organisational solution, yet centre productivity and sustainability are frequently dictated by the availability and security of infrastructure funds.Despite being widely cited as a core component of research capacity building, infrastructure as a discrete concept has been rather analytically neglected, often treated as an implicit feature of research environments with little specification or relegated to a narrow category of physical or administrative inputs. The terms research infrastructure, capacity, and culture, among others, are deployed in overlapping and inconsistent ways, further obfuscating the crucial functions of infrastructure specifically and its relationships with associated concepts.The case is made for an expanded conceptualisation of research infrastructure, one that moves beyond conventional 'hardware' notions. Drawing on a case analysis of NEXUS, a multidisciplinary health research centre based at the University of British Columbia, Canada, a conceptual framework is proposed that integrates the tangible and intangible structures that interactively underlie research centre functioning.A relational approach holds potential to allow for more comprehensive accounting of the returns on infrastructure investment. For those developing new research centres or seeking to reinvigorate existing ones, this framework may be a useful guide for both centre design and evaluation. PMID:20925953

  15. GEOWOW: a drought scenario for multidisciplinary data access and use

    NASA Astrophysics Data System (ADS)

    Santoro, Mattia; Sorichetta, Alessandro; Roglia, Elena; Craglia, Massimo; Nativi, Stefano

    2013-04-01

    Recent enhancements of the GEOSS Common Infrastructure (GCI; http://www.earthobservations.org/gci_gci.shtml), and in particular the introduction of a middleware in the GCI that brokers across heterogeneous information systems, have increased significantly the number of information resources discoverable worldwide. Now the challenge moves to the next level of ensuring access and use of the resources discovered, which have many different and domain-specific data models, communication protocols, encoding formats, etc. The GEOWOW Project - GEOSS interoperability for Weather, Ocean and Water, http://www.geowow.eu - developed a set of multidisciplinary use scenarios to advance the present GCI. This work describes the "Easy discovery and use of GEOSS resources for addressing multidisciplinary challenges related to drought scenarios" showcase demonstrated at the last GEO Plenary in Foz de Iguazu (Brazil). The scientific objectives of this showcase include: prevention and mitigation of water scarcity and drought situations, assessment of the population and geographical area potentially affected, evaluation of the possible distribution of mortality and economic loss risk, and support in building greater capacity to cope with drought. The need to address these challenges calls for producing scientifically robust and consistent information about the extent of land affected by drought and degradation. Similarly, in this context it is important: (i) to address uncertainties about the way in which various biological, physical, social, and economic factors interact each other and influence the occurrence of drought events, and (ii) to develop and test adequate indices and/or combination of them for monitoring and forecasting drought in different geographic locations and at various spatial scales (Brown et al., 2002). The scientific objectives above can be met with an increased interoperability across the multidisciplinary domains relevant to this drought scenario. In particular

  16. Towards the creation of a European Network of Earth Observation Networks within GEO. The ConnectinGEO project.

    NASA Astrophysics Data System (ADS)

    Masó, Joan; Serral, Ivette; Menard, Lionel; Wald, Lucien; Nativi, Stefano; Plag, Hans-Peter; Jules-Plag, Shelley; Nüst, Daniel; Jirka, Simon; Pearlman, Jay; De Maziere, Martine

    2015-04-01

    ConnectinGEO (Coordinating an Observation Network of Networks EnCompassing saTellite and IN-situ to fill the Gaps in European Observations" is a new H2020 Coordination and Support Action with the primary goal of linking existing Earth Observation networks with science and technology (S&T) communities, the industry sector, the Group on Earth Observations (GEO), and Copernicus. ConnectinGEO aims to facilitate a broader and more accessible knowledge base to support the needs of GEO, its Societal Benefit Areas (SBAs) and the users of the Global Earth Observing System of Systems (GEOSS). A broad range of subjects from climate, natural resources and raw materials, to the emerging UN Sustainable Development Goals (SDGs) will be addressed. The project will generate a prioritized list of critical gaps within available observation data and models to translate observations into practice-relevant knowledge, based on stakeholder consultation and systematic analysis. Ultimately, it will increase coherency of European observation networks, increase the use of Earth observations for assessments and forecasts and inform the planning for future observation systems. ConnectinGEO will initiate a European Network of Earth Observation Networks (ENEON) that will encompass space-based, airborne and in-situ observations networks. ENEON will be composed by project partners representing thematic observation networks along with the GEOSS Science and Technology Stakeholder Network, GEO Communities of Practices, Copernicus services, Sentinel missions and in-situ support data representatives, representatives of the space-based, airborne and in-situ observations European networks (e.g. EPOS, EMSO and GROOM, etc), representatives of the industry sector and European and national funding agencies, in particular those participating in the future ERA-PlaNET. At the beginning, the ENEON will be created and managed by the project. Then the management will be transferred to the network itself to ensure

  17. European PTTI report

    NASA Technical Reports Server (NTRS)

    Cordara, Franco; Grimaldi, Sabrina; Leschiutta, Sigfrido

    1994-01-01

    Time and frequency metrology in Europe presents some peculiar features in its three main components: research on clocks, comparisons and dissemination methods, and dissemination services. Apart from the usual activities of the national metrological laboratories, an increasing number of cooperation between the European countries are promoted inside some European organizations, such as the ECC, EFTA, EUROMET, and WECC. Cooperation between these organizations is covered. The present, evolving situation will be further influenced by the recent political changes in Eastern Europe.

  18. Management of precancerous conditions and lesions in the stomach (MAPS): guideline from the European Society of Gastrointestinal Endoscopy (ESGE), European Helicobacter Study Group (EHSG), European Society of Pathology (ESP), and the Sociedade Portuguesa de Endoscopia Digestiva (SPED)

    PubMed Central

    Dinis-Ribeiro, M.; Areia, M.; de Vries, A. C.; Marcos-Pinto, R.; Monteiro-Soares, M.; O'Connor, A.; Pereira, C.; Pimentel-Nunes, P.; Correia, R.; Ensari, A.; Dumonceau, J. M.; Machado, J. C.; Macedo, G.; Malfertheiner, P.; Matysiak-Budnik, T.; Megraud, F.; Miki, K.; O'Morain, C.; Peek, R. M.; Ponchon, T.; Ristimaki, A.; Rembacken, B.; Carneiro, F.; Kuipers, E. J.

    2012-01-01

    Atrophic gastritis, intestinal metaplasia, and epithelial dysplasia of the stomach are common and are associated with an increased risk for gastric cancer. In the absence of guidelines, there is wide disparity in the management of patients with these premalignant conditions. The European Society of Gastrointestinal Endoscopy (ESGE), the European Helicobacter Study Group (EHSG), the European Society of Pathology (ESP) and the Sociedade Portuguesa de Endoscopia Digestiva (SPED) have therefore combined efforts to develop evidence-based guidelines on the management of patients with precancerous conditions and lesions of the stomach (termed MAPS). A multidisciplinary group of 63 experts from 24 countries developed these recommendations by means of repeat online voting and a meeting in June 2011 in Porto, Portugal. The recommendations emphasize the increased cancer risk in patients with gastric atrophy and metaplasia, and the need for adequate staging in the case of high grade dysplasia, and they focus on treatment and surveillance indications and methods. PMID:22198778

  19. Preoperative multidisciplinary treatment with hyperthermia for soft tissue sarcoma.

    PubMed

    Makihata, E; Kuroda, M; Kawai, A; Ozaki, T; Sugihara, S; Inoue, H; Joja, I; Asaumi, J; Kawasaki, S; Hiraki, Y

    1997-04-01

    We report the results of phase I/II studies of preoperative multidisciplinary treatment of 14 patients with soft tissue sarcoma using hyperthermia from November 1990 to April 1995. The preoperative treatment was conducted with thermo-radio-chemotherapy in 11 cases of stage III, and with thermo-radiotherapy as well as thermo-chemotherapy in three cases of stages I and II. Hyperthermia was carried out twice a week with totals ranging from 4 to 14 times (average: 8.4 times); each session lasted 60 min. Radiotherapy was administered four or five times per week, and the dose was 1.8 2Gy/fraction, with a total of 30-40 Gy in a four week period. Chemotherapy was mainly in the form of MAID regimen (2-mercaptoethanesulphonic acid (mesna), adriamycin, ifosfamide and dacarbazine). The tumors were surgically resected in all patients after completing the preoperative treatment. The efficacy rate, as expressed by the percentage of either tumors in which reduction rate was 50% or more, or tumors for which post-treatment contrast enhanced CT image revealed low density volumes occupying 50% or more of the total mass, was 71% (ten of the 14 tumors). The mean tumor necrosis rate in the resected specimens was 78%. The tumor necrosis rate was significantly high (P < 0.05) in patients whose Time > or = 42 degrees C was of long duration. Postoperative complications were observed in six patients; among these, two patients developed wound infection that required surgical treatment as a complication of surgery performed in the early stage following the preoperative treatment. After a mean postoperative follow-up of 27 months, distant metastasis occurred in four patients resulting in three fatalities. The three-year cumulative survival rate was 64.3%. No local recurrence was observed in any patient during the follow-up, thus confirming our hypothesis that preoperative multidisciplinary treatment has an excellent local efficacy. We think that it would be valuable to conduct, at many

  20. New trends in the multidisciplinary treatment of liver tumors.

    PubMed

    Donati, Marcello; Basile, Francesco

    2013-08-01

    The authors report on new trends in the multidisciplinary treatment of liver tumors from the 3rd Interdisciplinary Treatment of Liver Tumors Congress in Essen, Germany. Novel aspects of molecular target-oriented therapies of hepatocarcinoma were reported, such as the current position of radiofrequency and microwave ablation of tumors compared with the new electroporation technique. State-of-the-art and new surgical trends in cholangiocarcinoma treatment were also discussed. The correlation of the biological behavior involved in the differentiation of melanomas with the treatment of liver metastasis was better defined. The role of neoadjuvant chemotherapy and combined strategies for colorectal liver metastasis were focused on intra-arterial therapeutic options. New data on neuroendocrine tumor liver metastases were also shared, leading to a better orientation for patient selection for surgical treatment. PMID:23902241

  1. Revisiting cardiovascular calcification: A multifaceted disease requiring a multidisciplinary approach.

    PubMed

    Hutcheson, Joshua D; Goettsch, Claudia; Rogers, Maximillian A; Aikawa, Elena

    2015-10-01

    The presence of cardiovascular calcification significantly predicts patients' morbidity and mortality. Calcific mineral deposition within the soft cardiovascular tissues disrupts the normal biomechanical function of these tissues, leading to complications such as heart failure, myocardial infarction, and stroke. The realization that calcification results from active cellular processes offers hope that therapeutic intervention may prevent or reverse the disease. To this point, however, no clinically viable therapies have emerged. This may be due to the lack of certainty that remains in the mechanisms by which mineral is deposited in cardiovascular tissues. Gaining new insight into this process requires a multidisciplinary approach. The pathological changes in cell phenotype that lead to the physicochemical deposition of mineral and the resultant effects on tissue biomechanics must all be considered when designing strategies to treat cardiovascular calcification. In this review, we overview the current cardiovascular calcification paradigm and discuss emerging techniques that are providing new insight into the mechanisms of ectopic calcification. PMID:26358815

  2. Recent Experiences in Multidisciplinary Analysis and Optimization, part 1

    NASA Technical Reports Server (NTRS)

    Sobieski, J. (Compiler)

    1984-01-01

    Papers presented at the NASA Symposium on Recent Experiences in Multidisciplinary Analysis and Optimization held at NASA Langley Research Center, Hampton, Virginia April 24 to 26, 1984 are given. The purposes of the symposium were to exchange information about the status of the application of optimization and associated analyses in industry or research laboratories to real life problems and to examine the directions of future developments. Information exchange has encompassed the following: (1) examples of successful applications; (2) attempt and failure examples; (3) identification of potential applications and benefits; (4) synergistic effects of optimized interaction and trade-offs occurring among two or more engineering disciplines and/or subsystems in a system; and (5) traditional organization of a design process as a vehicle for or an impediment to the progress in the design methodology.

  3. The fruits of collaboration in a multidisciplinary field

    PubMed Central

    Hu, Jun

    2010-01-01

    Collaboration between researchers and between research organizations is generally considered a desirable course of action, in particular by some funding bodies. However, collaboration within a multidisciplinary community, such as the Computer–Human Interaction (CHI) community, can be challenging. We performed a bibliometric analysis of the CHI conference proceedings to determine if papers that have authors from different organization or countries receive more citations than papers that are authored by members of the same organization. There was no significant difference between these three groups, indicating that there is no advantage for collaboration in terms of citation frequency. Furthermore, we tested if papers written by authors from different organizations or countries receive more best paper awards or at least award nominations. Papers from only one organization received significantly fewer nominations than collaborative papers. PMID:20927182

  4. Multidisciplinary aerospace design optimization: Survey of recent developments

    NASA Technical Reports Server (NTRS)

    Sobieszczanski-Sobieski, Jaroslaw; Haftka, Raphael T.

    1995-01-01

    The increasing complexity of engineering systems has sparked increasing interest in multidisciplinary optimization (MDO). This paper presents a survey of recent publications in the field of aerospace where interest in MDO has been particularly intense. The two main challenges of MDO are computational expense and organizational complexity. Accordingly the survey is focussed on various ways different researchers use to deal with these challenges. The survey is organized by a breakdown of MDO into its conceptual components. Accordingly, the survey includes sections on Mathematical Modeling, Design-oriented Analysis, Approximation Concepts, Optimization Procedures, System Sensitivity, and Human Interface. With the authors' main expertise being in the structures area, the bulk of the references focus on the interaction of the structures discipline with other disciplines. In particular, two sections at the end focus on two such interactions that have recently been pursued with a particular vigor: Simultaneous Optimization of Structures and Aerodynamics, and Simultaneous Optimization of Structures Combined With Active Control.

  5. PAYCOS: A new multidisciplinary analysis program for hypersonic vehicle design

    NASA Technical Reports Server (NTRS)

    Stubbe, J. R.

    1990-01-01

    The Payload Conceptual Sizing Code (PAYCOS), a new multidisciplinary computer program for use in the conceptual development phase of hypersonic lifting vehicles (HV's), is described. The program allows engineers to rapidly determine the feasibility of an HV concept and then improve upon the concept by means of optimization theory. The code contains analysis modules for aerodynamics, thermodynamics, mass properties, flight stability, controls, loads, structures, and packaging. Motivation for the code lies with the increased complexity of HV's over their body-of-revolution ballistic predecessors. With these new shapes, the need to rapidly screen out poor concepts and actively develop new and better concepts is an even more crucial part of the early design process. Preliminary results are given which demonstrate the optimization capabilities of the code.

  6. Multidisciplinary analysis of actively controlled large flexible spacecraft

    NASA Technical Reports Server (NTRS)

    Cooper, Paul A.; Young, John W.; Sutter, Thomas R.

    1986-01-01

    The control of Flexible Structures (COFS) program has supported the development of an analysis capability at the Langley Research Center called the Integrated Multidisciplinary Analysis Tool (IMAT) which provides an efficient data storage and transfer capability among commercial computer codes to aid in the dynamic analysis of actively controlled structures. IMAT is a system of computer programs which transfers Computer-Aided-Design (CAD) configurations, structural finite element models, material property and stress information, structural and rigid-body dynamic model information, and linear system matrices for control law formulation among various commercial applications programs through a common database. Although general in its formulation, IMAT was developed specifically to aid in the evaluation of the structures. A description of the IMAT system and results of an application of the system are given.

  7. Multidisciplinary Management of a Fused Tooth: A Case Report

    PubMed Central

    Sen Tunc, Emine; Arici, Nursel; Ozkan, Nilüfer

    2013-01-01

    Objective. Fusion is a dental anomaly that arises through the union of two adjacent teeth. The case report presents multidisciplinary management of a fused maxillary anterior tooth. Case Report. A 10-year-old boy was referred to the pediatric dental clinic with the chief complaint of a large upper anterior tooth. Intraoral and radiographic examinations indicated fusion between the permanent maxillary right central incisor and a supernumerary tooth. According to the treatment plan, the fused tooth was sectioned, and the mesial portion was removed. The remaining tooth section was restored with composite resin, and the diastema between the central incisors was closed with orthodontic treatment. After an 18-month followup period, the tooth showed no sign of pathosis. Conclusion. The technique described here offers a simple and effective method for restoring a fused tooth that reestablishes function, shape, and esthetics. PMID:24396611

  8. Repression predicts outcome following multidisciplinary treatment of chronic pain.

    PubMed

    Burns, J W

    2000-01-01

    This study examined whether repression predicts outcome following multidisciplinary treatment for chronic pain and whether links between anxiety and outcome are obscured by repressors. Ninety-three chronic pain patients completed a 4-week pain program. Lifting capacity, walking endurance, depression, pain severity, and activity were measured at pre- and posttreatment. Low-anxious, repressor, high-anxious, and defensive/high-anxious groups were formed from median splits of Anxiety Content (ACS) and Lie scales of the Minnesota Multiphasic Personality Inventory-2 (MMPI-2; Butcher, Dahlstrom, Graham, Tellegen, & Kaemmer, 1989). Significant ACS x Lie interactions were found for lifting capacity, depression, and pain severity changes. Planned comparisons showed that both repressors and high-anxious patients performed poorly on lifting capacity; repressors alone recovered poorly on depression and pain severity. Results imply that repression may interfere with the process and outcome of pain programs. PMID:10711590

  9. NASA Aeronautics Multidisciplinary Analysis and Design Fellowship Program

    NASA Technical Reports Server (NTRS)

    Grossman, B.; Gurdal, Z.; Kapania, R. K.; Mason, W. H.; Schetz, J. A.

    1999-01-01

    This program began as a grant from NASA Headquarters, NGT-10025, which was in effect from 10/l/93 until 10/31/96. The remaining funding for this effort was transferred from NASA Headquarters to NASA Langley and a new grant NGT-1-52155 was issued covering the period II/l/96 to 5/15/99. This report serves as the final report of NGT-1-52155. For a number of years, Virginia Tech had been on the forefront of research in the area of multidisciplinary analysis and design. In June of 1994, faculty members from aerospace and ocean engineering, engineering science and mechanics, mechanical engineering, industrial engineering, mathematics and computer sciences, at Virginia Tech joined together to form the Multidisciplinary Analysis and Design (MAD) Center for Advanced Vehicles. The center was established with the single goal: to perform research that is relevant to the needs of the US industry and to foster collaboration between the university, government and industry. In October of 1994, the center was chosen by NASA headquarters as one of the five university centers to establish a fellowship program to develop a graduate program in multidisciplinary analysis and design. The fellowship program provides full stipend and tuition support for seven U. S. students per year during their graduate studies. The grant is currently being administered by the NMO Branch of NASA Langley. To advise us regarding the problems faced by the industry, an industrial advisory board has been formed consisting of representatives from industry as well as government laboratories. The present membership includes major aerospace companies: Aurora Flight Sciences, Boeing: Philadelphia, Boeing: Long Beach, Boeing: Seattle, Boeing: St. Louis, Cessna, Ford, General Electric, Hughes, Lockheed-Martin: Palo Alto, Northrop-Grumman, Sikorsky, smaller, aerospace software companies: Aerosoft, Phoenix Integration and Proteus Engineering, along with representatives from government agencies, including: NASA Ames

  10. Multidisciplinary Care of the Patient with Chronic Obstructive Pulmonary Disease

    PubMed Central

    Kuzma, Anne Marie; Meli, Yvonne; Meldrum, Catherine; Jellen, Patricia; Butler-Lebair, Marianne; Koczen-Doyle, Debra; Rising, Peter; Stavrolakes, Kim; Brogan, Frances

    2008-01-01

    The National Emphysema Treatment Trial used a multidisciplinary team approach to implement the maximum medical care protocol, including adjustment of medications and outpatient pulmonary rehabilitation for all patients and nutritional and psychological counseling as needed. This article discusses the benefits of such an approach in the care of the patient with chronic obstructive pulmonary disease. Team member roles complement each other and contribute to the goal of providing the highest-quality medical care. The primary focus of the team is to reinforce the medical plan and to provide patient education and support. This article reviews the elements of the initial patient assessment and the functional and nutritional assessment. Patient education focuses on medication use, recognition and management of chronic obstructive pulmonary disease exacerbation symptoms, smoking cessation, advance directives, and travel. PMID:18453373

  11. Execution of Multidisciplinary Design Optimization Approaches on Common Test Problems

    NASA Technical Reports Server (NTRS)

    Balling, R. J.; Wilkinson, C. A.

    1997-01-01

    A class of synthetic problems for testing multidisciplinary design optimization (MDO) approaches is presented. These test problems are easy to reproduce because all functions are given as closed-form mathematical expressions. They are constructed in such a way that the optimal value of all variables and the objective is unity. The test problems involve three disciplines and allow the user to specify the number of design variables, state variables, coupling functions, design constraints, controlling design constraints, and the strength of coupling. Several MDO approaches were executed on two sample synthetic test problems. These approaches included single-level optimization approaches, collaborative optimization approaches, and concurrent subspace optimization approaches. Execution results are presented, and the robustness and efficiency of these approaches an evaluated for these sample problems.

  12. Need for multidisciplinary research towards a second green revolution.

    PubMed

    Wollenweber, Bernd; Porter, John R; Lübberstedt, Thomas

    2005-06-01

    Despite recent achievements in conventional plant breeding and genomics, the rate of increase of crop yields is declining and thus there is a need for a second green revolution. Advances within single disciplines, alone, cannot solve the challenges of increasing yield. As scientific disciplines have become increasingly diversified, a more complete understanding of the mechanisms by which genetic and environmental variation modify grain yield and composition is needed, so that specific quantitative and quality targets can be identified. To achieve this aim, the expertise of plant genomics, physiology and agronomy, as well as recently developed plant modelling techniques, must be combined. There has been recent progress in these individual disciplines, but multidisciplinary approaches must be implemented to tackle drought stress and salinity as major constraints to achieving sufficient grain yield in the future. PMID:15860432

  13. National Combustion Code: A Multidisciplinary Combustor Design System

    NASA Technical Reports Server (NTRS)

    Stubbs, Robert M.; Liu, Nan-Suey

    1997-01-01

    The Internal Fluid Mechanics Division conducts both basic research and technology, and system technology research for aerospace propulsion systems components. The research within the division, which is both computational and experimental, is aimed at improving fundamental understanding of flow physics in inlets, ducts, nozzles, turbomachinery, and combustors. This article and the following three articles highlight some of the work accomplished in 1996. A multidisciplinary combustor design system is critical for optimizing the combustor design process. Such a system should include sophisticated computer-aided design (CAD) tools for geometry creation, advanced mesh generators for creating solid model representations, a common framework for fluid flow and structural analyses, modern postprocessing tools, and parallel processing. The goal of the present effort is to develop some of the enabling technologies and to demonstrate their overall performance in an integrated system called the National Combustion Code.

  14. Evaluation of Methods for Multidisciplinary Design Optimization (MDO). Part 2

    NASA Technical Reports Server (NTRS)

    Kodiyalam, Srinivas; Yuan, Charles; Sobieski, Jaroslaw (Technical Monitor)

    2000-01-01

    A new MDO method, BLISS, and two different variants of the method, BLISS/RS and BLISS/S, have been implemented using iSIGHT's scripting language and evaluated in this report on multidisciplinary problems. All of these methods are based on decomposing a modular system optimization system into several subtasks optimization, that may be executed concurrently, and the system optimization that coordinates the subtasks optimization. The BLISS method and its variants are well suited for exploiting the concurrent processing capabilities in a multiprocessor machine. Several steps, including the local sensitivity analysis, local optimization, response surfaces construction and updates are all ideally suited for concurrent processing. Needless to mention, such algorithms that can effectively exploit the concurrent processing capabilities of the compute servers will be a key requirement for solving large-scale industrial design problems, such as the automotive vehicle problem detailed in Section 3.4.

  15. A multidisciplinary program to educate and advocate for living donors.

    PubMed

    Sites, Anita K; Freeman, Jason R; Harper, Michael R; Waters, David B; Pruett, Timothy L

    2008-12-01

    Education is critical in decision making and the informed consent process in prospective living donors. Little has been written about how and what living donors should be taught. This article describes a multidisciplinary program for living donor education at the University of Virginia. The goals of the program are to impart information needed for prospective donors to make an informed decision and to independently evaluate donors' medical and psychosocial suitability. A partnership between the transplant department and an independent donor advocacy team establishes an environment conducive to education. By embracing independence, transparency, partnership, and advocacy, our program permits bidirectional education. This partnership facilitates unbiased understanding and appreciation of this education and considers each individual's unique circumstances when making informed decisions. Likewise, prospective donors educate the team about their circumstances, which helps the team safeguard the prospective donor and may enhance the safety of prospective donors and the perceived integrity of living organ donation. PMID:19186581

  16. A Multidisciplinary Approach for Managing Severely Malaligned Lower Molars.

    PubMed

    Keinan, David; Birnboim-Blaum, Galit; Webber, Mariel

    2016-01-01

    An impacted mandibular molar is a common clinical situation that may damage adjacent teeth and impair periodontal health. Improper treatment brings the risk of damaging adjacent vital tissues. The risk can be reduced by early diagnosis and extraction of the impacted tooth by an experienced clinician. However, in clinical cases of two impacted molars, it may be beneficial for the patient to save at least one molar. This can be achieved by orthodontic alignment of one of the molars, while extracting the other. The decision should be based upon prognosis and risks for each procedure and for both teeth. The case presented here demonstrates a recommended clinical decision-making process before treatment, followed by monitored multidisciplinary treatment with adaptations made as the treatment progresses. PMID:26939154

  17. Multidisciplinary Management of Mastocytosis: Nordic Expert Group Consensus.

    PubMed

    Broesby-Olsen, Sigurd; Dybedal, Ingunn; Gülen, Theo; Kristensen, Thomas K; Møller, Michael B; Ackermann, Leena; Sääf, Maria; Karlsson, Maria A; Agertoft, Lone; Brixen, Kim; Hermann, Pernille; Stylianou, Eva; Mortz, Charlotte G; Torfing, Trine; Havelund, Troels; Sander, Birgitta; Bergström, Anna; Bendix, Marie; Garvey, Lene H; Bjerrum, Ole Weis; Valent, Peter; Bindslev-Jensen, Carsten; Nilsson, Gunnar; Vestergaard, Hanne; Hägglund, Hans

    2016-06-15

    Mastocytosis is a heterogeneous group of diseases defined by an increased number and accumulation of mast cells, and often also by signs and symptoms of mast cell activation. Disease subtypes range from indolent to rare aggressive forms. Mastocytosis affects people of all ages and has been considered rare; however, it is probably underdiagnosed with potential severe implications. Diagnosis can be challenging and symptoms may be complex and involve multiple organ-systems. In general it is advised that patients should be referred to centres with experience in the disease offering an individualized, multidisciplinary approach. We present here consensus recommendations from a Nordic expert group for the diagnosis and general management of patients with mastocytosis. PMID:26694951

  18. Thiopeptide engineering: a multidisciplinary effort towards future drugs.

    PubMed

    Just-Baringo, Xavier; Albericio, Fernando; Álvarez, Mercedes

    2014-06-23

    The recent development of thiopeptide analogues of antibiotics has allowed some of the limitations inherent to these naturally occurring substances to be overcome. Chemical synthesis, semisynthetic derivatization, and engineering of the biosynthetic pathway have independently led to complementary modifications of various thiopeptides. Some of the new substances have displayed improved profiles, not only as antibiotics, but also as antiplasmodial and anticancer drugs. The design of novel molecules based on the thiopeptide scaffold appears to be the only strategy to exploit the high potential they have shown in vitro. Herein we present the most relevant achievements in the production of thiopeptide analogues and also discuss the way the different approaches might be combined in a multidisciplinary strategy to produce more sophisticated structures. PMID:24861213

  19. Astronomy and development: a multidisciplinary project in the Mexican countryside

    NASA Astrophysics Data System (ADS)

    Bravo Alfaro, Hector; Caretta, César; Brito, Elcia M. S.

    2015-08-01

    We outline a long term project focused on children and young students living in rural places of the Mexican State of Guanajuato. This multidisciplinary project includes astronomers, environment engineers, biologists and sociologists of Universidad de Guanajuato. One part of the activities are done in situ, at the villages, and other is currently proposed to be held at the Public Astronomical Observatory of Universidad de Guanajuato. Organizing the trips and the activities for scholar groups at the observatory (where telescopes, computers and microscopes are available) would fit very well within several of the IAU-OAD strategies. We expect that, attending the FM20 of the IAU and presenting our results there will help us to develop regionalcollaborations and showing the many opportunities for new possible volunteers.

  20. Who's in CHARGE? Multidisciplinary management of patients with CHARGE association.

    PubMed Central

    Blake, K D; Russell-Eggitt, I M; Morgan, D W; Ratcliffe, J M; Wyse, R K

    1990-01-01

    Clinical experience of 50 patients with the CHARGE association is reviewed and problems with management of children born with multiple system involvement is highlighted. It was found that the outlook for survival was poor if more than one of the following three features was present: cyanotic cardiac lesions, bilateral posterior choanal atresia, or tracheo-oesophageal fistula. Mortality was largely due not to the structural heart defects or choanal abnormalities, but reflected underlying pharyngeal and laryngeal incoordination, which resulted in aspiration of secretions. Outcome is likely to be improved if collaboration between specialist surgical teams allows necessary procedures to be performed using the minimum number of anaesthetics. Examination of both the short and long term management of these children has stressed the importance of a multidisciplinary approach to their care. Images Figure 2 PMID:2317068

  1. Strategies for building a multidisciplinary academic program in women's health.

    PubMed

    Brown, A J

    1999-09-01

    During the decade of the 1990s, women's health has received unprecedented attention from government, industry, marketers of healthcare, and academic medical centers. An assessment of research, education, and healthcare delivery has exposed gaps in our knowledge about gender-related issues. Recognition of gender as a rich frontier for innovation and discovery has resulted in widespread and varied responses and a commensurate increase in activity in the field. However, this diversity of effort has created the new challenge of effectively communicating strategies of response to the multiple disciplines invested in women's health. This article describes a strategy used at Duke University Medical Center to build awareness of women's health through a highly visible and successful Women's Health Seminar Series. The series serves as a focal point for broader efforts to build a comprehensive, multidisciplinary, academic program in women's health with initiatives in clinical care, research, faculty development, provider education, and community outreach. PMID:10534301

  2. Multidisciplinary Approach for Patients Hospitalized With Heart Failure.

    PubMed

    Frankenstein, Lutz; Fröhlich, Hanna; Cleland, John G F

    2015-10-01

    Acute heart failure describes the rapid deterioration, over minutes, days or hours, of symptoms and signs of heart failure. Its management is an interdisciplinary challenge that requires the cooperation of various specialists. While emergency providers, (interventional) cardiologists, heart surgeons, and intensive care specialists collaborate in the initial stabilization of acute heart failure patients, the involvement of nurses, discharge managers, and general practitioners in the heart failure team may facilitate the transition from inpatient care to the outpatient setting and improve acute heart failure readmission rates. This review highlights the importance of a multidisciplinary approach to acute heart failure with particular focus on the chain-of-care delivered by the various services within the healthcare system. PMID:26409892

  3. Multidisciplinary study of Hewett Field, Zechstein Kalk Formation

    SciTech Connect

    West, K.L. )

    1994-04-01

    New technology and a multidisciplinary team approach were effectively used by Phillips Petroleum for optimum reservoir development in the Hewett field, North Sea. Near-horizontal drilling technology and depositional environment and fracture studies were used by engineering and geology. Geophysics contributed structure and porosity trend maps and used new technology developed by Phillips called Incremental Pay Thickness modeling. IPT modeling enhances the integration of well-log data and seismic wiggle traces so porosity and pay thickness can be estimated directly from seismic data. Seismic amplitude values were mapped and processed into estimated porosity thickness using the IPT mathematical relationship. This interpretation aided in locating three successful development wells in areas of predicted high porosity, which increased production by 67 MMCF/D and optimized recovery.

  4. The Role of Multiphysics Simulation in Multidisciplinary Analysis

    NASA Technical Reports Server (NTRS)

    Rifai, Steven M.; Ferencz, Robert M.; Wang, Wen-Ping; Spyropoulos, Evangelos T.; Lawrence, Charles; Melis, Matthew E.

    1998-01-01

    This article describes the applications of the Spectrum(Tm) Solver in Multidisciplinary Analysis (MDA). Spectrum, a multiphysics simulation software based on the finite element method, addresses compressible and incompressible fluid flow, structural, and thermal modeling as well as the interaction between these disciplines. Multiphysics simulation is based on a single computational framework for the modeling of multiple interacting physical phenomena. Interaction constraints are enforced in a fully-coupled manner using the augmented-Lagrangian method. Within the multiphysics framework, the finite element treatment of fluids is based on Galerkin-Least-Squares (GLS) method with discontinuity capturing operators. The arbitrary-Lagrangian-Eulerian method is utilized to account for deformable fluid domains. The finite element treatment of solids and structures is based on the Hu-Washizu variational principle. The multiphysics architecture lends itself naturally to high-performance parallel computing. Aeroelastic, propulsion, thermal management and manufacturing applications are presented.

  5. A grid generation system for multi-disciplinary design optimization

    NASA Technical Reports Server (NTRS)

    Jones, William T.; Samareh-Abolhassani, Jamshid

    1995-01-01

    A general multi-block three-dimensional volume grid generator is presented which is suitable for Multi-Disciplinary Design Optimization. The code is timely, robust, highly automated, and written in ANSI 'C' for platform independence. Algebraic techniques are used to generate and/or modify block face and volume grids to reflect geometric changes resulting from design optimization. Volume grids are generated/modified in a batch environment and controlled via an ASCII user input deck. This allows the code to be incorporated directly into the design loop. Generated volume grids are presented for a High Speed Civil Transport (HSCT) Wing/Body geometry as well a complex HSCT configuration including horizontal and vertical tails, engine nacelles and pylons, and canard surfaces.

  6. A generalized software executive for multidisciplinary computational structural dynamics

    NASA Technical Reports Server (NTRS)

    Berman, Alex

    1989-01-01

    The objective of this presentation is to introduce the attendees to the DYSCO program. The emphasis will be on the features which make it multidisciplinary. DYSCO is a very general and versatile software program which couples and solves dynamic systems. It was initiated in the late 1970's in response to a helicopter analysis requirement. The system development, however, resulted in an executive which was completely separated from any particular area of technology, except that of second order ordinary differential equations. During the course of its development, it was funded by the Army Aviation Applied Technology Directorate, the Air Force Wright Aeronautical Laboratories, and by the Kaman Aerospace Corporation. It is completely written in FORTRAN and is operational on IBM and VAX computers.

  7. Clinical features and multidisciplinary approaches to dementia care

    PubMed Central

    Grand, Jacob HG; Caspar, Sienna; MacDonald, Stuart WS

    2011-01-01

    Dementia is a clinical syndrome of widespread progressive deterioration of cognitive abilities and normal daily functioning. These cognitive and behavioral impairments pose considerable challenges to individuals with dementia, along with their family members and caregivers. Four primary dementia classifications have been defined according to clinical and research criteria: 1) Alzheimer’s disease; 2) vascular dementias; 3) frontotemporal dementias; and 4) dementia with Lewy bodies/Parkinson’s disease dementia. The cumulative efforts of multidisciplinary healthcare teams have advanced our understanding of dementia beyond basic descriptions, towards a more complete elucidation of risk factors, clinical symptoms, and neuropathological correlates. The characterization of disease subtypes has facilitated targeted management strategies, advanced treatments, and symptomatic care for individuals affected by dementia. This review briefly summarizes the current state of knowledge and directions of dementia research and clinical practice. We provide a description of the risk factors, clinical presentation, and differential diagnosis of dementia. A summary of multidisciplinary team approaches to dementia care is outlined, including management strategies for the treatment of cognitive impairments, functional deficits, and behavioral and psychological symptoms of dementia. The needs of individuals with dementia are extensive, often requiring care beyond traditional bounds of medical practice, including pharmacologic and non-pharmacologic management interventions. Finally, advanced research on the early prodromal phase of dementia is reviewed, with a focus on change-point models, trajectories of cognitive change, and threshold models of pathological burden. Future research goals are outlined, with a call to action for social policy initiatives that promote preventive lifestyle behaviors, and healthcare programs that will support the growing number of individuals affected by

  8. Salvaging the Infected Breast Tissue Expander: A Standardized Multidisciplinary Approach

    PubMed Central

    Selber, Jesse C.; Crosby, Melissa; Raad, Issam I.; Butler, Charles E.; Villa, Mark T.; Kronowitz, Steven J.; Clemens, Mark W.; Garvey, Patrick; Yang, Wei; Baumann, Donald P.

    2016-01-01

    Background: Infections of breast tissue expander (TE) are complex, often requiring TE removal and hospitalization, which can delay further adjuvant therapy and add to the overall costs of breast reconstruction. Therefore, to reduce the rate of TE removal, hospitalization, and costs, we created a standardized same-day multidisciplinary outpatient quality improvement protocol for diagnosing and treating patients with early signs of TE infection. Methods: We prospectively evaluated 26 consecutive patients who developed a surgical site infection between February 2013 and April 2014. On the same day, patients were seen in the Plastic Surgery and Infectious Diseases clinics, underwent breast ultrasonography with or without periprosthetic fluid aspiration, and were prescribed a standardized empiric oral or intravenous antimicrobial regimen active against biofilm-embedded microorganisms. All patients were managed as per our established treatment algorithm and were followed up for a minimum of 1 year. Results: TEs were salvaged in 19 of 26 patients (73%). Compared with TE-salvaged patients, TE-explanted patients had a shorter median time to infection (20 vs 40 days; P = 0.09), a significantly higher median temperature at initial presentation [99.8°F; interquartile range (IQR) = 2.1 vs 98.3°F; IQR = 0.4°F; P = 0.01], and a significantly longer median antimicrobial treatment duration (28 days; IQR = 27 vs 21 days; IQR = 14 days; P = 0.05). The TE salvage rates of patients whose specimen cultures yielded no microbial growth, Staphylococcus species, and Pseudomonas were 92%, 75%, and 0%, respectively. Patients who had developed a deep-seated pocket infection were significantly more likely than those with superficial cellulitis to undergo TE explantation (P = 0.021). Conclusions: Our same-day multidisciplinary diagnostic and treatment algorithm not only yielded a TE salvage rate higher than those previously reported but also decreased the rate of hospitalization, decreased

  9. A Matrix-Free Algorithm for Multidisciplinary Design Optimization

    NASA Astrophysics Data System (ADS)

    Lambe, Andrew Borean

    Multidisciplinary design optimization (MDO) is an approach to engineering design that exploits the coupling between components or knowledge disciplines in a complex system to improve the final product. In aircraft design, MDO methods can be used to simultaneously design the outer shape of the aircraft and the internal structure, taking into account the complex interaction between the aerodynamic forces and the structural flexibility. Efficient strategies are needed to solve such design optimization problems and guarantee convergence to an optimal design. This work begins with a comprehensive review of MDO problem formulations and solution algorithms. First, a fundamental MDO problem formulation is defined from which other formulations may be obtained through simple transformations. Using these fundamental problem formulations, decomposition methods from the literature are reviewed and classified. All MDO methods are presented in a unified mathematical notation to facilitate greater understanding. In addition, a novel set of diagrams, called extended design structure matrices, are used to simultaneously visualize both data communication and process flow between the many software components of each method. For aerostructural design optimization, modern decomposition-based MDO methods cannot efficiently handle the tight coupling between the aerodynamic and structural states. This fact motivates the exploration of methods that can reduce the computational cost. A particular structure in the direct and adjoint methods for gradient computation motivates the idea of a matrix-free optimization method. A simple matrix-free optimizer is developed based on the augmented Lagrangian algorithm. This new matrix-free optimizer is tested on two structural optimization problems and one aerostructural optimization problem. The results indicate that the matrix-free optimizer is able to efficiently solve structural and multidisciplinary design problems with thousands of variables and

  10. A Matrix-Free Algorithm for Multidisciplinary Design Optimization

    NASA Astrophysics Data System (ADS)

    Lambe, Andrew Borean

    Multidisciplinary design optimization (MDO) is an approach to engineering design that exploits the coupling between components or knowledge disciplines in a complex system to improve the final product. In aircraft design, MDO methods can be used to simultaneously design the outer shape of the aircraft and the internal structure, taking into account the complex interaction between the aerodynamic forces and the structural flexibility. Efficient strategies are needed to solve such design optimization problems and guarantee convergence to an optimal design. This work begins with a comprehensive review of MDO problem formulations and solution algorithms. First, a fundamental MDO problem formulation is defined from which other formulations may be obtained through simple transformations. Using these fundamental problem formulations, decomposition methods from the literature are reviewed and classified. All MDO methods are presented in a unified mathematical notation to facilitate greater understanding. In addition, a novel set of diagrams, called extended design structure matrices, are used to simultaneously visualize both data communication and process flow between the many software components of each method. For aerostructural design optimization, modern decomposition-based MDO methods cannot efficiently handle the tight coupling between the aerodynamic and structural states. This fact motivates the exploration of methods that can reduce the computational cost. A particular structure in the direct and adjoint methods for gradient computation. motivates the idea of a matrix-free optimization method. A simple matrix-free optimizer is developed based on the augmented Lagrangian algorithm. This new matrix-free optimizer is tested on two structural optimization problems and one aerostructural optimization problem. The results indicate that the matrix-free optimizer is able to efficiently solve structural and multidisciplinary design problems with thousands of variables and

  11. European Education, European Citizenship? On the Role of Education in Constructing Europeanness.

    ERIC Educational Resources Information Center

    Ollikainen, Aaro

    2000-01-01

    Focuses on the role of the European Union (EU) education programs in fostering a sense of European citizenship. Addresses the five meanings given to the concept of European citizenship: (1) recognition of European heritage; (2) EU loyalty; (3) right of free movement; (4) political participation; and (5) active citizenship. (CMK)

  12. GEO Standard and Interoperability Forum (SIF) European Team

    NASA Astrophysics Data System (ADS)

    Nativi, Stefano

    2010-05-01

    The European GEO SIF has been initiated by the GIGAS project in an effort to better coordinate European requirements for GEO and GEOSS related activities, and is recognised by GEO as a regional SIF. To help advance the interoperability goals of the Global Earth Observing System of Systems (GEOSS), the Group on Earth Observations (GEO) Architecture and Data Committee (ADC) has established a Standards and Interoperability Forum (SIF) to support GEO organizations offering components and services to GEOSS. The SIF will help GEOSS contributors understand how to work with the GEOSS interoperability guidelines and how to enter their "interoperability arrangements" (standards or other ad hoc arrangements for interoperability) into the GEOSS registries. This will greatly facilitate the utility of GEOSS and encourage significant increase in participation. To carry out its work most effectively, the SIF promotes to form Regional Teams. They will help to organize and optimize the support coming from the different parts of the World and reach out regional and multi-disciplinary Scientific Communities. This will allow to have true global representation in supporting GEOSS interoperability. A SIF European Team is foreseen. The main role of the SIF is facilitating interoperability and working with members and participating organizations as they offer data and information services to the users of GEOSS. In this framework, the purpose of having a European Regional Team is to increase efficiency in carrying out the work of the SIF. Experts can join the SIF European Team by registering at the SIF European Team wiki site: http://www.thegigasforum.eu/sif/

  13. WFPDB: European Plate Archives

    NASA Astrophysics Data System (ADS)

    Tsvetkov, Milcho

    2007-08-01

    The Wide-Field Plate Database (WFPDB) gives an inventory of all wide-field (>~ 1 sq. deg) photographic observations archived in astronomical institutions over the world. So it facilitates and stimulates their use and preservation as a valuable source of information for future investigations in astronomy. At present WFPDB manages plate-index information for 25% of all existing plates providing on-line access from Sofia (http://www.skyarchive.org/search) and in CDS, Strasbourg. Here we present the new development of WFPDB as an instrument for searching of long term brightness variations of different sky objects stressing on the European photographic plate collections (from existing 2 million wide-field plates more than 55% are in Europe: Germany, Russia, Ukraine, Italy, Czech Republic, etc.). We comment examples of digitization (with flatbed scanners) of the European plate archives in Sonneberg, Pulkovo, Asiago, Byurakan, Bamberg, etc. and virtual links of WFPDB with European AVO, ADS, IBVS.

  14. European Universe Awareness

    NASA Astrophysics Data System (ADS)

    Russo, P.; Miley, G.; Westra van Holthe, F.; Schrier, W.; Reed, S.

    2011-10-01

    The European Universe Awareness (EU-UNAWE) programme uses the beauty and grandeur of the cosmos to encourage young children, particularly those from underprivileged backgrounds, to develop an interest in science and technology and to foster a sense of global citizenship. EU-UNAWE is already active in 40 countries and comprises a global network of almost 500 astronomers, teachers and other educators. The programme was recently awarded a grant of 1.9 million euros by the European Union so that it can be further developed in five European countries and South Africa. The grant will be used to organise teacher training workshops and to develop educational materials, such as an astronomy news service for children and games. During this presentation we will outline some of the biggest achievements of EU-UNAWE to date and discuss future plans for the programme.

  15. Multidisciplinary teamwork in the treatment and rehabilitation of the head and neck cancer patient.

    PubMed

    King, G E; Lemon, J C; Martin, J W

    1992-06-01

    The advantages of multidisciplinary treatment planning of head and neck cancer patients is described. Planning rehabilitation concurrently with curing the malignancy results in the most effective application of treatment modalities coordinated with rehabilitative care. Concentrated multidisciplinary treatment reduces post treatment morbidity by shortening recovery and rehabilitation time. PMID:1631776

  16. A Case Study of a Co-Instructed Multidisciplinary Senior Capstone Project in Sustainability

    ERIC Educational Resources Information Center

    Rhee, Jinny; Oyamot, Clifton; Parent, David; Speer, Leslie; Basu, Anuradha; Gerston, Larry

    2014-01-01

    As societal challenges involving sustainable development increase, the need to effectively integrate this inherently multidisciplinary topic into existing curricula becomes more pressing. Multidisciplinary, team-taught, project-based instruction has shown effectiveness in teaching teamwork, communication, and life-long learning skills, and…

  17. Exploring Forms of Triangulation to Facilitate Collaborative Research Practice: Reflections from a Multidisciplinary Research Group

    ERIC Educational Resources Information Center

    Tiainen, Tarja; Koivunen, Emma-Reetta

    2006-01-01

    This article contains critical reflections of a multidisciplinary research group studying the human and technological dynamics around some newly offered electronic services in a specific rural area of Finland. For their research, the group adopted ethnography. On facing the challenges of doing ethnographic research in a multidisciplinary setting,…

  18. Exploring Electrochromics: A Series of Eye-Catching Experiments to Introduce Students to Multidisciplinary Research

    ERIC Educational Resources Information Center

    Small, Leo J.; Wolf, Steven; Spoerke, Erik D.

    2014-01-01

    Introducing students to a multidisciplinary research laboratory presents challenges in terms of learning specific technical skills and concepts but also with respect to integrating different technical elements to form a coherent picture of the research. Here we present a multidisciplinary series of experiments we have developed in the Electronic,…

  19. 78 FR 65675 - Proposed Collection; 60-Day Comment Request; Multidisciplinary Treatment Planning (MTP) Within...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-01

    ... on multidisciplinary care in cancer. A total of 21 hospitals participating in the NCCCP through June...; Multidisciplinary Treatment Planning (MTP) Within the National Cancer Institute (NCI) Community Cancer Centers... Cancer Institute (NCI), National Institutes of Health (NIH), will publish periodic summaries of...

  20. The Third Air Force/NASA Symposium on Recent Advances in Multidisciplinary Analysis and Optimization

    NASA Technical Reports Server (NTRS)

    1990-01-01

    The third Air Force/NASA Symposium on Recent Advances in Multidisciplinary Analysis and Optimization was held on 24-26 Sept. 1990. Sessions were on the following topics: dynamics and controls; multilevel optimization; sensitivity analysis; aerodynamic design software systems; optimization theory; analysis and design; shape optimization; vehicle components; structural optimization; aeroelasticity; artificial intelligence; multidisciplinary optimization; and composites.

  1. Energy: Multidisciplinary Activities for the Classroom. Top Hit Energy Lesson Plans, K-1, 2-6.

    ERIC Educational Resources Information Center

    National Energy Foundation, Salt Lake City, UT.

    This six-volume set of multidisciplinary instructional materials developed by the National Energy Foundation (NEF) presents energy activities for grades K-1, 2-6. The instructional materials are teacher-developed, teacher-tested, and multi-disciplinary. The lesson plans and activities are organized around seven goal areas of a NEF developed…

  2. E-Learning and Development: Lessons from Multi-Disciplinary Capacity Strengthening

    ERIC Educational Resources Information Center

    Babu, Suresh Chandra

    2014-01-01

    This paper documents the experience and lessons from implementing an e-learning program aimed at creating multidisciplinary research capacity. It presents a case study of bringing together a multidisciplinary group of professionals on-line to learn the skills needed to be a successful researcher in the context of HIV/AIDS and food security…

  3. RFID-Based Multidisciplinary Educational Platform to Improve the Engineering and Technology Curriculums

    ERIC Educational Resources Information Center

    Yelamarthi, Kumar

    2012-01-01

    Multidisciplinary projects involving electrical engineering (EE), mechanical engineering (ME), and computer engineering (CE) students are both exciting and difficult to conceptualize. Answering this challenge, this paper presents a multidisciplinary educational platform on radio frequency identification-based assistive devices. The combination of…

  4. Collaborative Design Processes: An Active and Reflective Learning Course in Multidisciplinary Collaboration.

    ERIC Educational Resources Information Center

    O'Brien, William J.; Soibelman, Lucio; Elvin, George

    2003-01-01

    In a capstone course, graduate students from two universities participated in collaborative design in the architectural, engineering, and construction industries in multidisciplinary teams via the Internet. Students also developed process designs to integrate technology into multidisciplinary teamwork, combining active and reflective learning.…

  5. European security and France

    SciTech Connect

    deRose, A.

    1985-01-01

    A French authority on security argues for new European initiatives in the face of the ''danger represented by Soviet military power deployed in support of an imperialistic ideology.'' His proposals, including the strengthening of conventional forces without abandoning the option of the first use of nuclear weapons, are meant to give substance to President Mitterrand's declaration in 1983: ''The European nations now need to realize that their defense is also their responsibility....'' A part of the increasingly important debate in France over defense policy in Europe.

  6. Multidisciplinary Optimization of a Transport Aircraft Wing using Particle Swarm Optimization

    NASA Technical Reports Server (NTRS)

    Sobieszczanski-Sobieski, Jaroslaw; Venter, Gerhard

    2002-01-01

    The purpose of this paper is to demonstrate the application of particle swarm optimization to a realistic multidisciplinary optimization test problem. The paper's new contributions to multidisciplinary optimization is the application of a new algorithm for dealing with the unique challenges associated with multidisciplinary optimization problems, and recommendations as to the utility of the algorithm in future multidisciplinary optimization applications. The selected example is a bi-level optimization problem that demonstrates severe numerical noise and has a combination of continuous and truly discrete design variables. The use of traditional gradient-based optimization algorithms is thus not practical. The numerical results presented indicate that the particle swarm optimization algorithm is able to reliably find the optimum design for the problem presented here. The algorithm is capable of dealing with the unique challenges posed by multidisciplinary optimization as well as the numerical noise and truly discrete variables present in the current example problem.

  7. Does Multidisciplinary Care Enhance the Management of Advanced Breast Cancer?: Evaluation of Advanced Breast Cancer Multidisciplinary Team Meetings

    PubMed Central

    Chirgwin, Jacquie; Craike, Melinda; Gray, Christine; Watty, Kathy; Mileshkin, Linda; Livingston, Patricia M.

    2010-01-01

    Purpose: To assess the contribution of the advanced breast cancer (ABC) multidisciplinary team meetings (MDMs) to patient care and clinical outcomes. Methods: Members of ABC MDMs at two health services completed questionnaires in November 2007. The questionnaire asked about the performance of the MDMs and their contribution to improvement in patient care in five domains: medical management, psychosocial care, palliative care, care in the community, and benefits for team members. A final section covered the perceived value and importance of the MDM in patient management. Descriptive statistics (frequencies, mean, and standard deviation) were used to summarize the performance, improvement, and importance scores. Results: A total of 27 multidisciplinary team members (73%) completed the questionnaire. The MDM performed best in medical management (mean performance score out of 5 [M] = 3.78) and palliative care (M = 3.77). These were also the areas that were most improved through the MDM. Benefits to team members and care in the community (both M = 3.05) ranked lowest by both measures. The MDM provided the most benefit for patient management in the areas of “awareness of services available” (M = 4.32), “efficiency of referrals” (M = 4.27) and “supportive care for patients” (M = 4.27). “Awareness of services available,” “psychological care for patients,” and “continuity of care” were considered the most important (M = 4.64). Conclusion: The study provides evidence that MDMs make an important contribution to the logistical and medical management of patients with advanced breast cancer. PMID:21358959

  8. Fixed point Open Ocean Observatory network (FixO3): Multidisciplinary observations from the air-sea interface to the deep seafloor

    NASA Astrophysics Data System (ADS)

    Lampitt, Richard; Cristini, Luisa

    2014-05-01

    The Fixed point Open Ocean Observatory network (FixO3) seeks to integrate the 23 European open ocean fixed point observatories and to improve access to these key installations for the broader community. These will provide multidisciplinary observations in all parts of the oceans from the air-sea interface to the deep seafloor. Coordinated by the National Oceanography Centre, UK, FixO3 builds on the significant advances achieved through the previous Europe-funded FP7 programmes EuroSITES, ESONET and CARBOOCEAN. Started in September 2013 with a budget of 7 Million Euros over 4 years the project has 29 partners drawn from academia, research institutions and SME's. In addition 12 international experts from a wide range of disciplines comprise an Advisory Board. On behalf of the FixO3 Consortium, we present the programme that will be achieved through the activities of 12 Work Packages: 1. Coordination activities to integrate and harmonise the current procedures and processes. Strong links will be fostered with the wider community across academia, industry, policy and the general public through outreach, knowledge exchange and training. 2. Support actions to offer a) free access to observatory infrastructures to those who do not have such access, and b) free and open data services and products. 3. Joint research activities to innovate and enhance the current capability for multidisciplinary in situ ocean observation. Support actions include Transnational Access (TNA) to FixO3 infrastructure, meaning that European organizations can apply to free-of-charge access to the observatories for research and testing in two international calls during the project lifetime. The first call for TNA opens in summer 2014. More information can be found on FixO3 website (www.fixo3.eu/). Open ocean observation is currently a high priority for European marine and maritime activities. FixO3 will provide important data on environmental products and services to address the Marine Strategy

  9. Teaching European Identities

    ERIC Educational Resources Information Center

    Raento, Pauliina

    2008-01-01

    The political, cultural and social make-up of Europe is changing fast. A new European identity is under construction, but old contradictions and diversity challenge its contents, forms and boundaries. Migration, the changing role of the nation-state and Europe's regions, the reshaping of politico-administrative and perceptional boundaries, the…

  10. The European VLBI network

    NASA Technical Reports Server (NTRS)

    Schilizzi, R. T.

    1980-01-01

    The capabilities of the European very long baseline interferometry (VLBI) network are summarized. The range of baseline parameters, sensitivities, and recording and other equipment available are included. Plans for upgrading the recording facilities and the use of geostationary satellites for signal transfer and clock synchronization are discussed.

  11. European Music Year 1985.

    ERIC Educational Resources Information Center

    Alexanderson, Thomas; And Others

    1984-01-01

    Articles concerning music are included in this newsletter dedicated to cultural venture to be jointly carried out by the Council of Europe and the European communities. Many events will mark Music Year 1985, including concerts, dance performances, operas, publications, recordings, festivals, exhibitions, competitions, and conferences on musical…

  12. Multilingualism in European Workplaces

    ERIC Educational Resources Information Center

    Gunnarsson, Britt-Louise

    2014-01-01

    This state-of-the-art article includes a review of past and recent studies on multilingualism at work in European environments. One aim is to provide the reader with a cross-cultural picture of workplace studies on various languages in Europe, another to discuss both positive and problem-based accounts of multilingualism at work. The overview…

  13. European Civilization. Teacher's Manual.

    ERIC Educational Resources Information Center

    Leppert, Ella C.; Halac, Dennis

    The instructional materials in this teaching guide for Course II, Unit IV, follow and build upon a previous sequential course described in SO 003 169 offering ninth grade students a study on the development of Western European Civilization. Focus is upon four periods of high development: The High Middle Ages (12th Century), The Renaissance (15th…

  14. Environmental monitoring in four European museums

    NASA Astrophysics Data System (ADS)

    Camuffo, Dario; Van Grieken, Rene; Busse, Hans-Jürgen; Sturaro, Giovanni; Valentino, Antonio; Bernardi, Adriana; Blades, Nigel; Shooter, David; Gysels, Kristin; Deutsch, Felix; Wieser, Monika; Kim, Oliver; Ulrych, Ursula

    In a European multidisciplinary research project concerning environmental diagnostics, museums have been selected, having different climate and pollution conditions, i.e.: Correr Museum, Venice (Italy); Kunsthistorisches Museum, Vienna (Austria); Royal Museum of Fine Arts, Antwerp (Belgium); Sainsbury Centre for Visual Arts, Norwich (UK). Some field tests investigated the microclimate, the gaseous and particulate air pollution and the biological contamination to suggest mitigative techniques that may reduce the potential for damage in the long run. Potential risk factors are generated by imbalance in temperature and humidity, generated by heating, air conditioning or ventilating system (HVAC), or the building structures, exchange of outside air, or large visitor numbers. HVAC may also enhance indoor gaseous pollution. Plants and carpets represent potential niches for bacterial colonisation. Pollutants and particles have been recognised having partly external and partly internal origin. Tourism has a direct negative impact, i.e. transport of external particles, release of heat, vapour and CO 2, as well as generation of turbulence, which increases the deposition rate of particulate matter. However, the main problem is that the microclimate has been planned for the well being of visitors during only the visiting time, disregarding the needs of conservation that requires a constant climate by day and by night. In some of these cases, better environmental niches have been obtained with the help of showcases. In other cases, showcases worsened the situation, especially when incandescent lamps were put inside.

  15. Evaluation of an 18-month commercial multidisciplinary obesity treatment programme.

    PubMed

    Aller, E E J G; van Baak, M A

    2016-02-01

    The treatment of obesity is an often studied subject. Although reductions in weight and improvements in cardiometabolic risk factors are important aims of obesity treatment, improvements in quality of life and eating behaviour are also relevant outcomes. In this practice-based study, we evaluated an 18-month commercial multidisciplinary obesity treatment programme and report on treatment results for weight, cardiometabolic risk factors, eating behaviour and quality of life. From a local commercial obesity treatment centre, 426 subjects (65% female; 45.4 ± 12.2 years; body mass index 40.0 ± 6.6 kg m(-2)) were recruited. Measurements of body weight, height, body composition, waist circumference and blood pressure were scheduled at baseline and every 3 months, whereas fasting blood collections were scheduled at baseline and every 6 months. At the same time points, participants were asked to fill in questionnaires on dietary intake, eating behaviour and quality of life. After 18 months of treatment programme, average weight change [mean (95% confidence interval)] was -10.9 kg (-14.8 to -7.0; P < 0.001) for the completers (n = 181) and -10.8 kg (-14.2 to -7.4; P < 0.001) for the intention-to-treat population (n = 426). Waist circumference (mean ± standard error of the mean) (-0.13 ± 0.01 cm; P < 0.001), fat mass (-7.8 ± 1.3 kg; P < 0.001) systolic (-11.4 ± 2.0; P < 0.001) and diastolic (-7.0 ± 1.3; P < 0.001) blood pressure, triglycerides (-0.4 ± 0.1; P = 0.004) and plasma glucose (-0.6 ± 0.2; P = 0.001) were significantly reduced. The PCS scale of the SF-36 and all three scales of the three-factor eating questionnaire improved significantly over the 18-month treatment period. All collected data in this study provide evidence that a multidisciplinary treatment programme based on lifestyle modification results in significant weight loss and improvements in cardiometabolic

  16. Integrating research infrastructures for solid Earth science in Europe: the European Plate Observing System

    NASA Astrophysics Data System (ADS)

    Cocco, M.; Giardini, D.; EPOS-PP Consortium

    2011-12-01

    The European Plate Observing System (EPOS) coordinates and integrates the research infrastructures in the European-Mediterranean region, to promote innovative approaches for a better understanding of the physical processes controlling earthquakes, volcanic eruptions, tsunamis as well as those driving tectonics and Earth surface dynamics. The EPOS 30-year plan aims at integrating the currently scattered, but highly advanced European facilities into one distributed, coherent multidisciplinary Research Infrastructure allowing sustainable long-term Earth science research strategies and an effective coordinated European-scale monitoring facility for solid Earth dynamics taking full advantage of new e-science opportunities. EPOS has been approved by ESFRI (the European Scientific Forum for Research Infrastructures) as one of the critical European Research Infrastructures, and the EPOS Preparatory Phase is supported by the European Commission FP7 program. The cooperation between EPOS and similar US infrastructures (i.e. Earthscope) will be ensured by dedicated NSF-EC funding. EPOS is integrating data from permanent national and regional geophysical monitoring networks (seismological, GPS), with the observations from "in-situ" observatories (volcano observatories, in-situ fault zone test sites) and temporary-monitoring and laboratory experiments through a cyber-infrastructure for data mining and processing, and facilities for data integration, archiving and exchange. The vision is to integrate these existing research infrastructures in order to increase the accessibility and usability of multidisciplinary data from monitoring networks, laboratory experiments and computational simulations enhancing worldwide interoperability in Earth Science by establishing a leading integrated European infrastructure and services. More recently the EPOS and the satellite Earth Observation communities are collaborating in order to promote the integration of data from in-situ monitoring

  17. Scientists attack European MRI rules

    NASA Astrophysics Data System (ADS)

    Harris, Margaret

    2010-08-01

    A report by the European Science Foundation (ESF) has sharply criticized a European Union (EU) directive on electromagnetic fields, arguing that limits on workers' exposure will have "potentially disastrous" consequences for magnetic resonance imaging (MRI).

  18. Improving outcomes in lung cancer: the value of the multidisciplinary health care team

    PubMed Central

    Denton, Eve; Conron, Matthew

    2016-01-01

    Lung cancer is a major worldwide health burden, with high disease-related morbidity and mortality. Unlike other major cancers, there has been little improvement in lung cancer outcomes over the past few decades, and survival remains disturbingly low. Multidisciplinary care is the cornerstone of lung cancer treatment in the developed world, despite a relative lack of evidence that this model of care improves outcomes. In this article, the available literature concerning the impact of multidisciplinary care on key measures of lung cancer outcomes is reviewed. This includes the limited observational data supporting improved survival with multidisciplinary care. The impact of multidisciplinary care on other benchmark measures of quality lung cancer treatment is also examined, including staging accuracy, access to diagnostic investigations, improvements in clinical decision making, better utilization of radiotherapy and palliative care services, and improved quality of life for patients. Health service research suggests that multidisciplinary care improves care coordination, leading to a better patient experience, and reduces variation in care, a problem in lung cancer management that has been identified worldwide. Furthermore, evidence suggests that the multidisciplinary model of care overcomes barriers to treatment, promotes standardized treatment through adherence to guidelines, and allows audit of clinical services and for these reasons is more likely to provide quality care for lung cancer patients. While there is strengthening evidence suggesting that the multidisciplinary model of care contributes to improvements in lung cancer outcomes, more quality studies are needed. PMID:27099511

  19. A Multidisciplinary Optimization Platform Applied to Steel Constructions

    NASA Astrophysics Data System (ADS)

    Benanane, Abdelkader; Caperaa, Serge; Said Bekkouche, M.; Kerdal, Djamel

    The design of the complex objects such as the buildings was always organized in levels of design since the preliminary phases to the final phases. If the approach by levels allows the designers to practise a precise and progressive definition to objects, it does not allow leading nevertheless to an optimal design of the projects. Consequently, we propose in this study, an original modelling allowing representing effectively all the process of the multidisciplinary design by the exchange of textual files (technical data and knowledge) between the different disciplines of the civil engineering (geotechnical studies, reinforced concrete and structural studies). We use for the loops of optimization the Monte-Carlo method because of its great robustness since it is based on the use of random numbers and the statistical tools, because it also puts up with any form of a function objective and allows to hold account easily constraints of optimization. The studies of test cases carried out on simple structures emphasize very significant and very promising variations as well as the dimensioning that the global cost.

  20. Multidisciplinary Expert-aided Analysis and Design (MEAD)

    NASA Technical Reports Server (NTRS)

    Hummel, Thomas C.; Taylor, James

    1989-01-01

    The MEAD Computer Program (MCP) is being developed under the Multidisciplinary Expert-Aided Analysis and Design (MEAD) Project as a CAD environment in which integrated flight, propulsion, and structural control systems can be designed and analyzed. The MCP has several embedded computer-aided control engineering (CACE) packages, a user interface (UI), a supervisor, a data-base manager (DBM), and an expert system (ES). The supervisor monitors and coordinates the operation of the CACE packages, the DBM; the ES, and the UI. The DBM tracks the control design process. Models created or installed by the MCP are tracked by date and version, and results are associated with the specific model version with which they were generated. The ES is used to relieve the control engineer from tedious and cumbersome tasks in the iterative design process. The UI provides the capability for a novice as well as an expert to utilize the MCP easily and effectively. The MCP version 2(MCP-2.0) is fully developed for flight control system design and analysis. Propulsion system modeling, analysis, and simulation is also supported; the same is true for structural models represented in state-space form. The ultimate goal is to cover the integration of flight, propulsion, and structural control engineering, including all discipline-specific functionality and interfaces. The current MCP-2.0 components and functionality are discussed.

  1. Needle localization breast biopsy: a model for multidisciplinary quality assurance.

    PubMed

    Howe, J R; Monsees, B; Destouet, J; Seib, J; Dehner, L P; Kraybill, W G

    1995-04-01

    As part of the quality assurance role of the Cancer Committee at Barnes Hospital, an institutional audit of Needle Localization Breast Biopsy (NLBB) was performed. Mammographic, operative, and surgical pathology reports from 370 consecutive patients at our institution undergoing both mammography and needle localization biopsy over a 34-month interval were reviewed. Carcinoma was diagnosed pathologically in 103 patients (28%), and 27% of these proved to be noninvasive. Sixteen patients were found to have histologic or clinical involvement of the axillary nodes; no patients with Tis lesions were found to have axillary nodal involvement. Of the patients, 73% were found to have either Stage 0 or Stage I disease, and 61% with an established malignancy had mastectomy (67% of patients with invasive carcinoma, 44% of those with carcinoma-in-situ), whereas 39% had some form of conservation therapy (33% of patients with invasive lesions, 56% of those with carcinoma-in-situ). Our results have been compared with other published studies, and important clinical indicators for evaluating the results of individual centers performing NLBB are discussed. It is concluded that NLBB is a safe and effective method of biopsying nonpalpable breast lesions, which allows for the identification of early stage breast carcinomas. In the present environment of concerns about the quality of care and costs, it is the responsibility of each center performing NLBB periodically to evaluate their results with this multidisciplinary procedure and to bring about change in those areas found to be deficient. PMID:7723366

  2. [Idiopatic pulmonary fibrosis - news in multidisciplinary diagnostic and therapeutic approaches].

    PubMed

    Vašáková, Martina; Matěj, Radoslav

    2016-01-01

    Idiopathic pulmonary fibrosis (IPF) is a primary fibrosing pulmonary process. Due to the ineffectiveness of current therapeutic strategies and unfavorable prognosis, IPF is the most serious example of idiopathic interstitial lung diseases (ILD). Etiology and pathogenesis of this disorder have not been fully clarified yet; but it is anticipated, that the fibroproliferation is caused by the imbalance of reparative and immunologic processes in the genetically predisposed patients. Radiologically and histopathologically, IPF is characterized by specific pattern called usual interstitial pneumonia (UIP), however, this pattern is not fully typical in all cases, and, moreover, it could be seen in other ILD´s, e.g. chronic hypersensitivity pneumonitis, asbestosis, autoimmune connective tissue diseases and many others as well. The final diagnosis of IPF is a consensual result of multidisciplinary team composed of pulmologist, pathologist and radiologist. IPF was an incurable disease with prognosis worse than cancer till the year 2011, when antifibrotic drugs decelerating a progression of this disease have been introduced. Earlier and correct diagnosis of IPF is the most important issue for the patients because they could be effectively treated and thus, prolonging their survival as much as possible. PMID:27223586

  3. Reflections on knowledge brokering within a multidisciplinary research team.

    PubMed

    Urquhart, Robin; Porter, Geoffrey A; Grunfeld, Eva

    2011-01-01

    Knowledge brokering (KB) may be one approach of helping researchers and decision makers effectively communicate their needs and abilities, and move toward increased use of evidence in health care. A multidisciplinary research team in Nova Scotia, Canada, has created a dedicated KB position with the goal of improving access to quality colorectal cancer care. The purpose of this paper is to provide an in-progress perspective on KB within this large research team. A KB position ("knowledge broker") was created to perform two primary tasks: (1) facilitate ongoing communication among team members; and (2) develop and maintain collaborations between researchers and decision makers to establish partnerships for the transfer and use of research findings. In this article, we discuss our KB model and its implementation, describe the broker's functions and activities, and present preliminary outcomes. The primary functions of the KB position have included: sustaining team members' engagement; harnessing members' expertise and sharing it with others; developing and maintaining communication tools/strategies; and establishing collaborations between team members and other stakeholders working in cancer care. The broker has facilitated an integrated knowledge translation approach to research conduct and led to the development of new collaborations with external stakeholders and other cancer/health services researchers. KB roles will undoubtedly differ across contexts. However, descriptive assessments can help others determine whether such an approach could be valuable for their research programs and, if so, what to expect during the process. PMID:22189993

  4. Systematic Review of Multidisciplinary Chronic Pain Treatment Facilities.

    PubMed

    Fashler, Samantha R; Cooper, Lynn K; Oosenbrug, Eric D; Burns, Lindsay C; Razavi, Shima; Goldberg, Lauren; Katz, Joel

    2016-01-01

    This study reviewed the published literature evaluating multidisciplinary chronic pain treatment facilities to provide an overview of their availability, caseload, wait times, and facility characteristics. A systematic literature review was conducted using PRISMA guidelines following a search of MEDLINE, PsycINFO, and CINAHL databases. Inclusion criteria stipulated that studies be original research, survey more than one pain treatment facility directly, and describe a range of available treatments. Fourteen articles satisfied inclusion criteria. Results showed little consistency in the research design used to describe pain treatment facilities. Availability of pain treatment facilities was scarce and the reported caseloads and wait times were generally high. A wide range of medical, physical, and psychological pain treatments were available. Most studies reported findings on the percentage of practitioners in different health care professions employed. Future studies should consider using more comprehensive search strategies to survey facilities, improving clarity on what is considered to be a pain treatment facility, and reporting on a consistent set of variables to provide a clear summary of the status of pain treatment facilities. This review highlights important information for policymakers on the scope, demand, and accessibility of pain treatment facilities. PMID:27445618

  5. Multidisciplinary approaches to understanding collective cell migration in developmental biology.

    PubMed

    Schumacher, Linus J; Kulesa, Paul M; McLennan, Rebecca; Baker, Ruth E; Maini, Philip K

    2016-06-01

    Mathematical models are becoming increasingly integrated with experimental efforts in the study of biological systems. Collective cell migration in developmental biology is a particularly fruitful application area for the development of theoretical models to predict the behaviour of complex multicellular systems with many interacting parts. In this context, mathematical models provide a tool to assess the consistency of experimental observations with testable mechanistic hypotheses. In this review, we showcase examples from recent years of multidisciplinary investigations of neural crest cell migration. The neural crest model system has been used to study how collective migration of cell populations is shaped by cell-cell interactions, cell-environmental interactions and heterogeneity between cells. The wide range of emergent behaviours exhibited by neural crest cells in different embryonal locations and in different organisms helps us chart out the spectrum of collective cell migration. At the same time, this diversity in migratory characteristics highlights the need to reconcile or unify the array of currently hypothesized mechanisms through the next generation of experimental data and generalized theoretical descriptions. PMID:27278647

  6. Educating primary care providers about HIV disease: multidisciplinary interactive mechanisms.

    PubMed Central

    Macher, A; Goosby, E; Barker, L; Volberding, P; Goldschmidt, R; Balano, K B; Williams, A; Hoenig, L; Gould, B; Daniels, E

    1994-01-01

    As HIV-related prophylactic and therapeutic research findings continue to evolve, the Health Resources and Services Administration (HRSA) of the Public Health Service has created multidisciplinary mechanisms to disseminate new treatment options and educate primary care providers at rural and urban sites throughout our nation's health care system. HRSA has implemented (a) the International State-of-the-Art HIV Clinical Conference Call Series, (b) the national network of AIDS Education and Training Centers, (c) the nationwide HIV Telephone Consultation Service, and (d) the Clinical Issues Subcommittee of the HRSA AIDS Advisory Committee. These collaborative and comprehensive efforts at HIV information dissemination target physicians, nurses, physician assistants, dentists, clinical pharmacists, mental health care providers, case managers, and allied health professionals. The sites where they provide care include public health clinics; county, State and Federal correctional facilities; private practice offices; community and academic hospitals; military and Veterans Administration facilities; hemophilia centers; schools of medicine, nursing, and dentistry; departments of health; chronic care facilities; visiting nurse and home care agencies; health maintenance organizations; and Indian Health Service clinics and hospitals. PMID:8190853

  7. Multidisciplinary management of hepatocellular carcinoma: where are we today?

    PubMed

    Marrero, Jorge A

    2013-02-01

    Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related death worldwide, and the incidence of HCC continues to rise. Improved understanding of risk factors for HCC has allowed the development of more effective prevention and surveillance strategies to reduce the global burden of this malignancy. Because of the complex nature of HCC, arising in a background of chronic liver dysfunction and often associated with viral infection, appropriate treatment requires a multidisciplinary approach designed to control the cancer and treat the underlying liver disease. Treatment approaches vary based on disease stage and severity, making accurate diagnosis and staging of disease critical. This has been aided by the development of new staging criteria, such as the Barcelona Clinic Liver Cancer Staging System. For earlier-stage disease, resection, radiofrequency ablation, transplantation, and transarterial chemoembolization (TACE) are preferred treatment modalities that provide optimal outcome. Until recently, few treatment options existed for patients with more advanced disease. Improved understanding of the underlying biology of the disease and the development of molecularly targeted therapies, including the multitargeted angiokinase inhibitor sorafenib, has improved outcomes in this patient population. Research into therapeutic targets and novel agents continues for more advanced disease. PMID:23457037

  8. Multidisciplinary marine environmental database for the Aral Sea

    NASA Astrophysics Data System (ADS)

    Lyubartsev, V. G.; Vladymyrov, V. L.; Myroshnychenko, V. V.

    2004-06-01

    Special unique database management and processing system ( Oceanbase) have been developed to work with the large sets of multivariable interdisciplinary oceanographic and environmental data. AralBase system developed to work with the Aral Sea interdisciplinary data is a variety of the OceanBase. AralBase is a special database application with the expanded functionality designed to explore large multidisciplinary oceanographic and environmental data sets. It provides many possibilities for data loading, selection, access, processing, analysis, preview and export. The AralBase has a customizing user-friendly multi-windows interface. A user can create his/her own desktops and open and arrange as many windows as he/she needs. The most valuable feature of AralBase is the integration of many service tools that allow the user to carry out almost all data processing without any additional software. At the moment, the database is loaded with the oceanographic and meteorological data provided by the participants of the Inco-Copernicus Aral-Kum Project. The OceanBase system and the AralBase, in particular, are the very flexible systems, and they can be used in any environmental and oceanographic project or institution dealing with the water environment (ocean, lakes, rivers) data. The preloaded data bases with the Data Explorer system module can be distributed among the interested scientists and experts to simplify drastically their work with data.

  9. Automatic differentiation of advanced CFD codes for multidisciplinary design

    NASA Technical Reports Server (NTRS)

    Bischof, C.; Corliss, G.; Green, L.; Griewank, A.; Haigler, K.; Newman, P.

    1992-01-01

    Automated multidisciplinary design of aircraft and other flight vehicles requires the optimization of complex performance objectives with respect to a number of design parameters and constraints. The effect of these independent design variables on the system performance criteria can be quantified in terms of sensitivity derivatives which must be calculated and propagated by the individual discipline simulation codes. Typical advanced CFD analysis codes do not provide such derivatives as part of a flow solution; these derivatives are very expensive to obtain by divided (finite) differences from perturbed solutions. It is shown that sensitivity derivatives can be obtained accurately and efficiently using the ADIFOR source translator for automatic differentiation. In particular, it is demonstrated that the 3-D, thin-layer Navier-Stokes, multigrid flow solver called TLNS3D is amenable to automatic differentiation in the forward mode even with its implicit iterative solution algorithm and complex turbulence modeling. It is significant that by using computational differentiation, consistent discrete nongeometric sensitivity derivatives have been obtained from an aerodynamic 3-D CFD code in a relatively short time, e.g., O(man-week) not O(man-year).

  10. Bowel endometriosis: colorectal surgeon's perspective in a multidisciplinary surgical team.

    PubMed

    Wolthuis, Albert M; Meuleman, Christel; Tomassetti, Carla; D'Hooghe, Thomas; de Buck van Overstraeten, Anthony; D'Hoore, André

    2014-11-14

    Endometriosis is a gynecological condition that presents as endometrial-like tissue outside the uterus and induces a chronic inflammatory reaction. Up to 15% of women in their reproductive period are affected by this condition. Deep endometriosis is defined as endometriosis located more than 5 mm beneath the peritoneal surface. This type of endometriosis is mostly found on the uterosacral ligaments, inside the rectovaginal septum or vagina, in the rectosigmoid area, ovarian fossa, pelvic peritoneum, ureters, and bladder, causing a distortion of the pelvic anatomy. The frequency of bowel endometriosis is unknown, but in cases of bowel infiltration, about 90% are localized on the sigmoid colon or the rectum. Colorectal involvement results in alterations of bowel habits such as constipation, diarrhea, tenesmus, dyschezia, and, rarely, rectal bleeding. Differential diagnosis must be made in case of irritable bowel syndrome, solitary rectal ulcer syndrome, and a rectal tumor. A precise diagnosis about the presence, location, and extent of endometriosis is necessary to plan surgical treatment. Multidisciplinary laparoscopic treatment has become the standard of care. Depending on the size of the lesion and site of involvement, full-thickness disc excision or bowel resection needs to be performed by an experienced colorectal surgeon. Long-term outcomes, following bowel resection for severe endometriosis, regarding pain and recurrence rate are good with a pregnancy rate of 50%. PMID:25400445

  11. Psychopathological aspects of kidney transplantation: Efficacy of a multidisciplinary team

    PubMed Central

    De Pasquale, Concetta; Veroux, Massimiliano; Indelicato, Luisa; Sinagra, Nunzia; Giaquinta, Alessia; Fornaro, Michele; Veroux, Pierfrancesco; Pistorio, Maria L

    2014-01-01

    Renal transplantation is a well established treatment for end-stage renal disease, allowing most patients to return to a satisfactory quality of life. Studies have identified many problems that may affect adaptation to the transplanted condition and post-operative compliance. The psychological implications of transplantation have important consequences even on strictly physical aspects. Organ transplantation is very challenging for the patient and acts as an intense stressor stimulus to which the patient reacts with neurotransmitter and endocrine-metabolic changes. Transplantation can result in a psychosomatic crisis that requires the patient to mobilize all bio-psycho-social resources during the process of adaptation to the new foreign organ which may result in an alteration in self-representation and identity, with possible psychopathologic repercussions. These reactions are feasible in mental disorders, e.g., post-traumatic stress disorder, adjustment disorder, and psychosomatic disorders. In organ transplantation, the fruitful collaboration between professionals with diverse scientific expertise, calls for both a guarantee for mental health and greater effectiveness in challenging treatments for a viable association between patients, family members and doctors. Integrated and multidisciplinary care should include uniform criteria and procedures for standard assessments, for patient autonomy, adherence to therapy, new coping strategies and the adoption of more appropriate lifestyles. PMID:25540735

  12. Multidisciplinary approach to converting power chair into motorized prone cart.

    PubMed

    Brose, Steven W; Wali, Eisha

    2014-01-01

    Pressure ulcers remain a major source of morbidity and mortality in veterans with neurologic impairment. Management of pressure ulcers typically involves pressure relief over skin regions containing wounds, but this can lead to loss of mobility and independence when the wounds are located in regions that receive pressure from sitting. An innovative, low-cost, multidisciplinary effort was undertaken to maximize quality of life in a veteran with a thoracic-4 level complete spinal cord injury and a stage 4 ischial wound. The person's power wheelchair was converted into a motorized prone cart, allowing navigation of the Department of Veterans Affairs spinal cord injury hospital ward and improved socialization while relieving pressure on the wound. Physical and occupational therapy assisted with the reconfiguration of the power chair and verified safe transfers into the chair and driving of the device. Psychology verified positive psychosocial benefit, while nursing and physician services verified an absence of unwanted pain or skin injury resulting from use of the device. Further investigation of ways to apply this technique is warranted to improve the quality of life of persons with pressure ulcers. PMID:25786192

  13. Hyperthermotherapy added to the multidisciplinary therapy for penile cancer.

    PubMed

    Kuroda, M; Tsushima, T; Nasu, Y; Asaumi, J; Nishikawa, K; Gao, X S; Joja, I; Takeda, Y; Togami, I; Makihata, E

    1993-06-01

    We performed a long-term follow-up of 4 patients with penile cancer who underwent hyperthermotherapy from August 1985 until August 1992. Hyperthermia was applied using a frequency of 350 MHz with a waveguide applicator twice a week for 60 min each for an average of 9.5 times (varying from 6 to 13 times). The total heating time that the temperature of urethra could be kept above 42 degrees C, was 166 min on the average (ranging from 0 to 463 min). Two patients classified as stage I according to the Jackson classification and 1 patient classified as stage IV underwent combined radiotherapy and received an average radiation dose of 53 Gy (range, 40-70 Gy). Among these patients 2 underwent combined chemotherapy with bleomycin or peplomycin. Malignant cells disappeared posttherapeutically and in August 1992, after an average of 5 years and 9 months (varying from 4 years 6 months to 6 years 10 months), the patients were free of recurrences. The one patient on stage IV had extensive invasion of the abdominal wall, but still recovered completely. One patient on stage III underwent combined chemotherapy and hyperthermotherapy, but heating had obviously been insufficient. There was a residue of malignant cells after the treatment and we performed a penectomy. Regarding functional preservation of the penis a multidisciplinary therapy incorporating hyperthermotherapy can be expected to increase the curativity. This indicates that it could induce in an advanced case, where an operation would be difficult, complete remission. PMID:8379345

  14. Coupled Multi-Disciplinary Optimization for Structural Reliability and Affordability

    NASA Technical Reports Server (NTRS)

    Abumeri, Galib H.; Chamis, Christos C.

    2003-01-01

    A computational simulation method is presented for Non-Deterministic Multidisciplinary Optimization of engine composite materials and structures. A hypothetical engine duct made with ceramic matrix composites (CMC) is evaluated probabilistically in the presence of combined thermo-mechanical loading. The structure is tailored by quantifying the uncertainties in all relevant design variables such as fabrication, material, and loading parameters. The probabilistic sensitivities are used to select critical design variables for optimization. In this paper, two approaches for non-deterministic optimization are presented. The non-deterministic minimization of combined failure stress criterion is carried out by: (1) performing probabilistic evaluation first and then optimization and (2) performing optimization first and then probabilistic evaluation. The first approach shows that the optimization feasible region can be bounded by a set of prescribed probability limits and that the optimization follows the cumulative distribution function between those limits. The second approach shows that the optimization feasible region is bounded by 0.50 and 0.999 probabilities.

  15. The MUSES Satellite Team and Multidisciplinary System Engineering

    NASA Technical Reports Server (NTRS)

    Chen, John C.; Paiz, Alfred R.; Young, Donald L.

    1997-01-01

    In a unique partnership between three minority-serving institutions and NASA's Jet Propulsion Laboratory, a new course sequence, including a multidisciplinary capstone design experience, is to be developed and implemented at each of the schools with the ambitious goal of designing, constructing and launching a low-orbit Earth-resources satellite. The three universities involved are North Carolina A&T State University (NCA&T), University of Texas, El Paso (UTEP), and California State University, Los Angeles (CSULA). The schools form a consortium collectively known as MUSES - Minority Universities System Engineering and Satellite. Four aspects of this project make it unique: (1) Including all engineering disciplines in the capstone design course, (2) designing, building and launching an Earth-resources satellite, (3) sustaining the partnership between the three schools to achieve this goal, and (4) implementing systems engineering pedagogy at each of the three schools. This paper will describe the partnership and its goals, the first design of the satellite, the courses developed at NCA&T, and the implementation plan for the course sequence.

  16. A multidisciplinary Earth science research program in China

    NASA Astrophysics Data System (ADS)

    Dong, Shuwen; Li, Tingdong; Gao, Rui; Hou, Hesheng; Li, Yingkang; Zhang, Shihong; Keller, G. Randy; Liu, Mian

    2011-09-01

    Because China occupies a large and geologically complex region of central and eastern Asia, the country may hold the keys to resolving many basic problems in the Earth sciences, such as how continental collision with India produced China's interconnected array of large intraplate structures, and what links exist between these structures and natural resources. To learn more, the Chinese government has launched SinoProbe, a major research initiative focusing on multidisciplinary imaging of the three-dimensional (3-D) structure and composition of the Chinese continental lithosphere and its evolution through geologic history. This effort is also motivated by China's need for a comprehensive and systematic evaluation of its natural resources and a better understanding of potential geohazards. SinoProbe is funded by the Chinese Ministry of Finance, managed by the Chinese Ministry of Land and Resources, and organized by the Chinese Academy of Geological Sciences. More than 960 investigators and engineers are currently involved with the program, not counting international collaborators. Most of them are affiliated with the Chinese Academy of Geological Sciences, the Chinese Academy of Sciences, the Ministry of Education (i.e., universities), and the China Earthquake Administration. The initial phase of the program (2008-2012), with funding equivalent to about US$164 million, is testing the feasibility of new technologies in geophysical and geochemical exploration and deep continental drilling by focusing on a series of profiles (Figure 1).

  17. Psychopathological aspects of kidney transplantation: Efficacy of a multidisciplinary team.

    PubMed

    De Pasquale, Concetta; Veroux, Massimiliano; Indelicato, Luisa; Sinagra, Nunzia; Giaquinta, Alessia; Fornaro, Michele; Veroux, Pierfrancesco; Pistorio, Maria L

    2014-12-24

    Renal transplantation is a well established treatment for end-stage renal disease, allowing most patients to return to a satisfactory quality of life. Studies have identified many problems that may affect adaptation to the transplanted condition and post-operative compliance. The psychological implications of transplantation have important consequences even on strictly physical aspects. Organ transplantation is very challenging for the patient and acts as an intense stressor stimulus to which the patient reacts with neurotransmitter and endocrine-metabolic changes. Transplantation can result in a psychosomatic crisis that requires the patient to mobilize all bio-psycho-social resources during the process of adaptation to the new foreign organ which may result in an alteration in self-representation and identity, with possible psychopathologic repercussions. These reactions are feasible in mental disorders, e.g., post-traumatic stress disorder, adjustment disorder, and psychosomatic disorders. In organ transplantation, the fruitful collaboration between professionals with diverse scientific expertise, calls for both a guarantee for mental health and greater effectiveness in challenging treatments for a viable association between patients, family members and doctors. Integrated and multidisciplinary care should include uniform criteria and procedures for standard assessments, for patient autonomy, adherence to therapy, new coping strategies and the adoption of more appropriate lifestyles. PMID:25540735

  18. A review of analgesic and emotive breathing: a multidisciplinary approach

    PubMed Central

    Bordoni, Bruno; Marelli, Fabiola; Bordoni, Giovannni

    2016-01-01

    The diaphragm is the primary muscle involved in breathing and other non-primarily respiratory functions such as the maintenance of correct posture and lumbar and sacroiliac movement. It intervenes to facilitate cleaning of the upper airways through coughing, facilitates the evacuation of the intestines, and promotes the redistribution of the body’s blood. The diaphragm also has the ability to affect the perception of pain and the emotional state of the patient, functions that are the subject of this article. The aim of this article is to gather for the first time, within a single text, information on the nonrespiratory functions of the diaphragm muscle and its analgesic and emotional response functions. It also aims to highlight and reflect on the fact that when the diaphragm is treated manually, a daily occurrence for manual operators, it is not just an area of musculature that is treated but the entire body, including the psyche. This reflection allows for a multidisciplinary approach to the diaphragm and the collaboration of various medical and nonmedical practitioners, with the ultimate goal of regaining or improving the patient’s physical and mental well-being. PMID:27013884

  19. [Sensory functions and Alzheimer's disease: a multi-disciplinary approach].

    PubMed

    Kenigsberg, Paul-Ariel; Aquino, Jean-Pierre; Berard, Alain; Boucart, Muriel; Bouccara, Didier; Brand, Gérard; Charras, Kevin; Garcia-Larrea, Luis; Gzil, Fabrice; Krolak-Salmon, Pierre; Madjlessi, Arach; Malaquin-Pavan, Évelyne; Penicaud, Luc; Platel, Hervé; Pozzo, Thierry; Reintjens, Christophe; Salmon, Éric; Vergnon, Laurent; Robert, Philippe

    2015-09-01

    Relations between sensory functions and Alzheimer's disease are still under-explored. To understand them better, the Fondation Médéric Alzheimer has brought together a multi-disciplinary expert group. Aristote's five senses must be enhanced by today's knowledge of proprioception, motor cognition and pain perception. When cognition breaks down, the person with dementia perceives the world around her with her sensory experience, yet is unable to integrate all this information to understand the context. The treatment of multiple sensory inputs by the brain is closely linked to cognitive processes. Sensory deficits reduce considerably the autonomy of people with dementia in their daily life and their relations with others, increase their social isolation and the risk of accidents. Professionals involved with neurodegenerative diseases remain poorly aware of sensory deficits, which can bias the results of cognitive tests. However, there are simple tools to detect these deficits, notably for vision, hearing and balance disorders, which can be corrected. Many interventions for cognitive rehabilitation or quality of life improvement are based on sensory functions. The environment of people with dementia must be adapted to become understandable, comfortable, safe and eventually therapeutic. PMID:26395297

  20. XML-Based Visual Specification of Multidisciplinary Applications

    NASA Technical Reports Server (NTRS)

    Al-Theneyan, Ahmed; Jakatdar, Amol; Mehrotra, Piyush; Zubair, Mohammad

    2001-01-01

    The advancements in the Internet and Web technologies have fueled a growing interest in developing a web-based distributed computing environment. We have designed and developed Arcade, a web-based environment for designing, executing, monitoring, and controlling distributed heterogeneous applications, which is easy to use and access, portable, and provides support through all phases of the application development and execution. A major focus of the environment is the specification of heterogeneous, multidisciplinary applications. In this paper we focus on the visual and script-based specification interface of Arcade. The web/browser-based visual interface is designed to be intuitive to use and can also be used for visual monitoring during execution. The script specification is based on XML to: (1) make it portable across different frameworks, and (2) make the development of our tools easier by using the existing freely available XML parsers and editors. There is a one-to-one correspondence between the visual and script-based interfaces allowing users to go back and forth between the two. To support this we have developed translators that translate a script-based specification to a visual-based specification, and vice-versa. These translators are integrated with our tools and are transparent to users.

  1. Viscoelastic Methods of Blood Clotting Assessment – A Multidisciplinary Review

    PubMed Central

    Benes, Jan; Zatloukal, Jan; Kletecka, Jakub

    2015-01-01

    Viscoelastic methods (VEM) made available the bedside assessment of blood clotting. Unlike standard laboratory tests, the results are based on the whole blood coagulation and are available in real time at a much faster turnaround time. In combination with our new knowledge about pathophysiology of the trauma-induced coagulopathy, the goal-oriented treatment protocols have been recently proposed for the initial management of bleeding in trauma victims. Additionally, the utility of viscoelastic monitoring devices has been proved even outside this setting in cardiosurgical patients or those undergoing liver transplantation. Many other situations were described in literature showing the potential use of bedside analysis of coagulation for the management of bleeding or critically ill patients. In the near future, we may expect further improvement in current bedside diagnostic tools enabling not only the assessment of secondary hemostasis but also the platelet aggregation. More sensitive assays for new anticoagulants are underway. Aim of this review is to offer the reader a multidisciplinary overview of VEM and their potential use in anesthesiology and critical care. PMID:26442265

  2. Overall Profile of a Pediatric Multidisciplinary Feeding Clinic

    PubMed Central

    2016-01-01

    Objective To evaluate the overall profile of children with feeding disorders and their relationships to medical conditions in an outpatient feeding clinic of a tertiary hospital. Methods The medical records of 143 children who had visited the feeding clinic between January 2010 and June 2014 were reviewed retrospectively. The presence of a feeding disorder (feeding behavior disorder, dysphagia, and/or failure to thrive [FTT]) and the children's medical conditions were examined by a physiatrist. Results Half of the patients (n=74, 51.7%) were under 15 months of age, and 68 (47.6%) were born preterm. Ninety-three patients (65.0%) met the criteria for any combination of feeding behavior disorder, dysphagia, or FTT. Cardiorespiratory disease was the most common medical condition; children with this condition were more likely to show sensory food aversion and FTT. Feeding behavior disorders were significantly associated with gastrointestinal problems, and dysphagia was significantly related to almost all medical conditions. Conclusion A multidisciplinary approach to children with feeding difficulties is proposed for comprehensive evaluation and treatment because combinations of feeding problems are very common among children. This overall profile could provide clinicians with a clear understanding of the complexity of feeding disorders and their relationships with various medical conditions in children. PMID:27606276

  3. NCC: A Multidisciplinary Design/Analysis Tool for Combustion Systems

    NASA Technical Reports Server (NTRS)

    Liu, Nan-Suey; Quealy, Angela

    1999-01-01

    A multi-disciplinary design/analysis tool for combustion systems is critical for optimizing the low-emission, high-performance combustor design process. Based on discussions between NASA Lewis Research Center and the jet engine companies, an industry-government team was formed in early 1995 to develop the National Combustion Code (NCC), which is an integrated system of computer codes for the design and analysis of combustion systems. NCC has advanced features that address the need to meet designer's requirements such as "assured accuracy", "fast turnaround", and "acceptable cost". The NCC development team is comprised of Allison Engine Company (Allison), CFD Research Corporation (CFDRC), GE Aircraft Engines (GEAE), NASA Lewis Research Center (LeRC), and Pratt & Whitney (P&W). This development team operates under the guidance of the NCC steering committee. The "unstructured mesh" capability and "parallel computing" are fundamental features of NCC from its inception. The NCC system is composed of a set of "elements" which includes grid generator, main flow solver, turbulence module, turbulence and chemistry interaction module, chemistry module, spray module, radiation heat transfer module, data visualization module, and a post-processor for evaluating engine performance parameters. Each element may have contributions from several team members. Such a multi-source multi-element system needs to be integrated in a way that facilitates inter-module data communication, flexibility in module selection, and ease of integration.

  4. Multidisciplinary optimization of controlled space structures with global sensitivity equations

    NASA Technical Reports Server (NTRS)

    Padula, Sharon L.; James, Benjamin B.; Graves, Philip C.; Woodard, Stanley E.

    1991-01-01

    A new method for the preliminary design of controlled space structures is presented. The method coordinates standard finite element structural analysis, multivariable controls, and nonlinear programming codes and allows simultaneous optimization of the structures and control systems of a spacecraft. Global sensitivity equations are a key feature of this method. The preliminary design of a generic geostationary platform is used to demonstrate the multidisciplinary optimization method. Fifteen design variables are used to optimize truss member sizes and feedback gain values. The goal is to reduce the total mass of the structure and the vibration control system while satisfying constraints on vibration decay rate. Incorporating the nonnegligible mass of actuators causes an essential coupling between structural design variables and control design variables. The solution of the demonstration problem is an important step toward a comprehensive preliminary design capability for structures and control systems. Use of global sensitivity equations helps solve optimization problems that have a large number of design variables and a high degree of coupling between disciplines.

  5. Multidisciplinary effort in treating children with hepatoblastoma in China.

    PubMed

    Yuan, Xiao-Jun; Wang, Huan-Min; Jiang, Hui; Tang, Meng-Jie; Li, Zhang-Lin; Zou, Xiang; Fang, Yong-Jun; Pan, Ci; Tou, Jin-Fa; Zhang, Ke-Ren; Liu, Xiang; Li, Wei-Song; Li, Yang; Lu, Jun; Wu, Ye-Ming

    2016-05-28

    The purpose of this study is to report the first nationwide protocol (Wuhan Protocol) developed by Chinese Children's Cancer Group and the results of multidisciplinary effort in treating hepatoblastoma. In this study, we reported the final analysis, which includes 153 hepatoblastoma patients in 13 hospitals from January 2006 to December 2013. The 6-year overall survival and event-free survival rates were 83.3 ± 3.1% and 71.0 ± 3.7%, respectively, in this cohort. The univariate analysis revealed that female (P = 0.027), under 5 years of age (P = 0.039), complete surgical resection (P = 0.000), no metastases (P = 0.000), and delayed surgery following neoadjuvant chemotherapy (P = 0.000) had better prognosis. In multivariate analysis, male, 5 years of age or above, stage PRETEXT III or IV, and incomplete surgical resection were among the some adverse factors contributing to poor prognosis. The preliminary results from this study showed that patients who underwent treatment following Wuhan Protocol had similar OS and EFS rates compared to those in developed countries. However, the protocol remains to be further optimized in standardizing surgical resection (including liver transplantation), refining risk stratification and risk-based chemotherapy. PMID:26945966

  6. Lessons Learned During Solutions of Multidisciplinary Design Optimization Problems

    NASA Technical Reports Server (NTRS)

    Patnaik, Suna N.; Coroneos, Rula M.; Hopkins, Dale A.; Lavelle, Thomas M.

    2000-01-01

    Optimization research at NASA Glenn Research Center has addressed the design of structures, aircraft and airbreathing propulsion engines. During solution of the multidisciplinary problems several issues were encountered. This paper lists four issues and discusses the strategies adapted for their resolution: (1) The optimization process can lead to an inefficient local solution. This deficiency was encountered during design of an engine component. The limitation was overcome through an augmentation of animation into optimization. (2) Optimum solutions obtained were infeasible for aircraft and air-breathing propulsion engine problems. Alleviation of this deficiency required a cascading of multiple algorithms. (3) Profile optimization of a beam produced an irregular shape. Engineering intuition restored the regular shape for the beam. (4) The solution obtained for a cylindrical shell by a subproblem strategy converged to a design that can be difficult to manufacture. Resolution of this issue remains a challenge. The issues and resolutions are illustrated through six problems: (1) design of an engine component, (2) synthesis of a subsonic aircraft, (3) operation optimization of a supersonic engine, (4) design of a wave-rotor-topping device, (5) profile optimization of a cantilever beam, and (6) design of a cvlindrical shell. The combined effort of designers and researchers can bring the optimization method from academia to industry.

  7. Xenotransplantation as a model of integrated, multidisciplinary research

    PubMed Central

    Bosio, Erika; Seveso, Michela; Rubello, Domenico; Ancona, Ermanno

    2009-01-01

    Xenotransplantation was proposed a long time ago as a possible solution to the world-wide shortage of human organs. For years, researchers in this field have almost exclusively directed their efforts towards combating the immunological barrier that precluded long-term xenograft survival. Studies have been conducted in both small and large animal models and the most relevant results have been obtained in pre-clincal studies, specifically those utilising the pig-to-nonhuman primate combination. In this context, a better understanding of the immunological mechanisms underlying the rejection of a xenograft have allowed the identification of specific targets of intervention that have resulted in considerable improvements in survival of porcine organs or cells in nonhuman primates. However it has also become apparent that if xenotransplantation has to enter the clinical arena, a multidisciplinary approach will be needed to comprehensively tackle the different issues related to the use of a xenograft to cure human disease. In this regard, the safety, ethics and regulatory aspects of xenotransplantation are currently being aggressively addressed to enable the initiation of xenotransplantation with a favourable risk/benefit ratio. PMID:19568350

  8. Multidisciplinary care in severe pediatric electrical oral burn.

    PubMed

    Pontini, A; Reho, F; Giatsidis, G; Bacci, C; Azzena, B; Tiengo, C

    2015-05-01

    Oral burns in pediatric patient are commonly due to electrical injuries, representing an important reconstructive issue even for functional than esthetic reason. Different classification, surgical management and even oral device were described to allow the best long-term result. In most case a multidisciplinary approach is necessary to achieve a satisfactory outcome. A severe case of pediatric oral burn with germinative teeth damage is presented, describing a multispecialist team approach that guarantee a satisfactory outcome by reconstructive surgery, careful progressive evaluation of dental and soft tissue healing and speech recovery. The use of acellular dermal substitute template within traditional reconstructive surgery had provided a good functional and esthetic result joint to valid preservation of germinative dental element as shown at long-term X-ray evaluation. Intensive rehabilitation speech program has also avoided phonetic impairment in an important speech develop period. It was so evident that the necessity of a multispecialist care in such difficult injury to achieve the best long-term result. PMID:25716757

  9. Treatment timing and multidisciplinary approach in Apert syndrome

    PubMed Central

    Fadda, Maria Teresa; Ierardo, Gaetano; Ladniak, Barbara; Di Giorgio, Gianni; Caporlingua, Alessandro; Raponi, Ingrid; Silvestri, Alessandro

    2015-01-01

    Summary Apert syndrome is a rare congenital disorder characterized by craniosynostosis, midface hypoplasia and symmetric syndactyly of hands and feet. Abnormalities associated with Apert syndrome include premature fusion of coronal sutures system (coronal sutures and less frequently lambdoid suture) resulting in brachiturricephalic dismorphism and impaired skull base growth. After this brief explanation it is clear that these anatomical abnormalities may have a negative impact on the ability to perform essential functions. Due to the complexity of the syndrome a multidisciplinary (respiratory, cerebral, maxillo-mandibular, dental, ophthalmic and orthopaedic) approach is necessary in treating the psychological, aesthetic and functional issues. The aim of this paper is to analyse the different functional issues and surgical methods trying to enhance results through a treatment plan which includes different specialities involved in Apert syndrome treatment. Reduced intellectual capacity is associated to the high number of general anaesthesia the small patients are subject to. Therefore the diagnostic and therapeutic treatment plan in these patients has established integrated and tailored surgical procedures based on the patients’ age in order to reduce the number of general anaesthesia, thus simplifying therapy for both Apert patients and their family members. PMID:26330906

  10. Multidisciplinary management of placenta percreta complicated by embolic phenomena.

    PubMed

    Styron, A G; George, R B; Allen, T K; Peterson-Layne, C; Muir, H A

    2008-07-01

    Hemorrhage and thrombosis are major causes of maternal mortality. This case discusses the management of a woman with placenta percreta complicated by intraoperative pulmonary embolism. A 39-year-old gravida 3 with two previous cesarean deliveries presented at 34 weeks of gestation with an antepartum hemorrhage. Magnetic resonance imaging confirmed placenta percreta. The multidisciplinary group including obstetricians, gynecological oncologists, interventional radiologists and anesthesiologists developed a delivery plan. Cesarean delivery was performed with internal iliac artery occlusion and embolization catheters in place. After the uterine incision our patient experienced acute hypotension and hypoxia associated with a drop in the end-tidal carbon dioxide and sinus tachycardia. She was resuscitated and the uterus closed with the placenta in situ. Postoperatively, uterine bleeding was arrested by immediate uterine artery embolization. With initiation of embolization, hypotension and hypoxia recurred. Oxygenation and hemodynamics slowly improved, the case continued and the patient was extubated uneventfully at the end of the procedure. Computed tomography revealed multiple pulmonary emboli. The patient was anticoagulated with low-molecular-weight heparin and returned six weeks later for hysterectomy. Placenta percreta with invasion into the bladder can be catastrophic if not recognized before delivery. The chronology of events suggests that this may have been amniotic fluid emboli. An intact placenta with abnormal architecture, such as placenta percreta, may increase the risk of amniotic fluid embolus. The clinical findings and co-existing filling defects on computed tomography may represent a spectrum of amniotic fluid embolism syndrome. PMID:18501584

  11. Multidisciplinary Treatment of a Fenestration-type Defect.

    PubMed

    Travassos, Rafael; Soares, Bruno; Bhandi, Shilpa H; Silva, Monica Barros da; Bandéca, Matheus Coelho; Mouchrek, José Carlos Elias; Silva, Vanessa Camila da; Benatti, Bruno Braga

    2015-04-01

    The case report aimed at treating a fenestration-type defect with multidisciplinary conventional and advanced surgical techniques. Fenestrations are isolated areas in which the exposed root surface is covered only by the periosteum and gingiva, but the remaining cortical bone remains intact. Root coverage is indicated in cases of root hypersensitivity, treatment of shallow caries lesions, cervical abrasions, and esthetic and cosmetic needs. In this case report, after proper hygiene instruction and dental biofilm control, a fenestration-type defect was treated using guided tissue regeneration (anorganic bovine matrix and resorbable membrane) and a connective tissue grafts, associated to an endodontic apicoectomy. After reevaluation, the remaining gingival recession was treated with a second gingival connective tissue graft covered with q double papillae type in order to reconstruct the periodontal tissues of the involved tooth. In this clinical case, the interaction between the different areas of dentistry has made it possible to correct a fenestration-type defect, following procedures based on scientific evidence, restoring periodontal health, esthetics, self-esteem, and meeting the patient's expectations regarding her initial complaint. This case report shows the important role of interdisciplinary approach to treating a patient with a complex periodontal defect that required different types of knowledge and abilities to achieve the best results based on the current status of dentistry possibilities. PMID:26067739

  12. Systematic Review of Multidisciplinary Chronic Pain Treatment Facilities

    PubMed Central

    Fashler, Samantha R.; Cooper, Lynn K.; Oosenbrug, Eric D.; Burns, Lindsay C.; Razavi, Shima; Goldberg, Lauren; Katz, Joel

    2016-01-01

    This study reviewed the published literature evaluating multidisciplinary chronic pain treatment facilities to provide an overview of their availability, caseload, wait times, and facility characteristics. A systematic literature review was conducted using PRISMA guidelines following a search of MEDLINE, PsycINFO, and CINAHL databases. Inclusion criteria stipulated that studies be original research, survey more than one pain treatment facility directly, and describe a range of available treatments. Fourteen articles satisfied inclusion criteria. Results showed little consistency in the research design used to describe pain treatment facilities. Availability of pain treatment facilities was scarce and the reported caseloads and wait times were generally high. A wide range of medical, physical, and psychological pain treatments were available. Most studies reported findings on the percentage of practitioners in different health care professions employed. Future studies should consider using more comprehensive search strategies to survey facilities, improving clarity on what is considered to be a pain treatment facility, and reporting on a consistent set of variables to provide a clear summary of the status of pain treatment facilities. This review highlights important information for policymakers on the scope, demand, and accessibility of pain treatment facilities. PMID:27445618

  13. Managing chronic pain with nonopioid analgesics: a multidisciplinary consult.

    PubMed

    Clauw, Daniel; McCarberg, Bill H

    2012-05-01

    As detailed in this online CME activity (www.cmeaccess.com/AJM/ChronicPain04), determining pain mechanism is an important aspect guiding treatment selection for chronic musculoskeletal pain states. Although broad classifications provide a framework, any combination of mechanisms may be present in a chronic pain patient, and there is growing evidence that pain states generally considered nociceptive may also involve elements of augmented central nervous system pain processing. Nonopioid analgesics, including serotonin norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants, and alpha-2-delta ligand anticonvulsants, are the treatments of choice for fibromyalgia and other central neuropathic pain states. Additionally, studies have now shown that certain SNRIs can be effective in treating "classic" nociceptive pain states, such as osteoarthritis, and also are effective for low back pain. In addition to considering biological mechanisms, chronic pain management also involves recognizing and evaluating the contribution of psychological and sociocultural factors that can influence pain chronicity and patient prognosis. A multimodal/multidisciplinary approach incorporating pharmacologic and nonpharmacologic therapy into a program that includes more than 1 discipline is important to improve outcomes in patients with chronic pain. PMID:22482859

  14. Osteogenesis imperfecta: from diagnosis and multidisciplinary treatment to future perspectives.

    PubMed

    Bregou Bourgeois, Aline; Aubry-Rozier, Bérengère; Bonafé, Luisa; Laurent-Applegate, Lee; Pioletti, Dominique P; Zambelli, Pierre-Yves

    2016-01-01

    Osteogenesis imperfecta is an inherited connective tissue disorder with wide phenotypic and molecular heterogeneity. A common issue associated with the molecular abnormality is a disturbance in bone matrix synthesis and homeostasis inducing bone fragility. In very early life, this can lead to multiple fractures and progressive bone deformities, including long bone bowing and scoliosis. Multidisciplinary management improves quality of life for patients with osteogenesis imperfecta. It consists of physical therapy, medical treatment and orthopaedic surgery as necessary. Medical treatment consists of bone-remodelling drug therapy. Bisphosphonates are widely used in the treatment of moderate to severe osteogenesis imperfecta, from infancy to adulthood. Other more recent drug therapies include teriparatide and denosumab. All these therapies target the symptoms and have effects on the mechanical properties of bone due to modification of bone remodelling, therefore influencing skeletal outcome and orthopaedic surgery. Innovative therapies, such as progenitor and mesenchymal stem cell transplantation, targeting the specific altered pathway rather than the symptoms, are in the process of development. PMID:27346233

  15. Effective glycemic management in hospitalized patients: a multidisciplinary approach.

    PubMed

    Bolton, Margaret; Richard, Anita; Blonde, Lawrence; Burshell, Alan

    2007-01-01

    The dual purpose of this process paper is to describe the implementation of an intensive insulin infusion program against multiple barriers, despite the increasing evidence in the literature supporting glycemic control, and to report the glucose outcomes. Traditional hyperglycemic management has been done either by subcutaneous sliding scale or intravenous insulin infusions based on absolute glucose numbers. A review of the literature, with particular evidence within the cardiothoracic surgical (CTS) population, has shown significant deleterious effects of even mild hyperglycemia.Increasing evidence supporting prevention of hyperglycemia, along with an unsatisfactory review of current methods used in-house, prompted the initiation of a pilot program to improve current methods utilizing insulin therapy. A multidisciplinary committee was formed consisting of the director of the intensive care unit, a dietician, a nursing unit director, a charge nurse, an endocrinologist, and two endocrinology nurse practitioners with extensive experience in intensive insulin therapy, including continuous subcutaneous insulin infusion. A review of literature was performed to evaluate available data and intravenous insulin infusion algorithms used by published authors. The CTS population was chosen as well as the intensive care unit. Nursing barriers in particular were extensive, and the use of a velocity driven insulin protocol required didactic instruction as well as individual reinforcement. All education, algorithm development, and oversight of patients were primarily performed by the nurse practitioners with immediate endocrinologist availability if needed. A review of glucose results indicated a significant reduction in hyperglycemia with a decrease in hypoglycemia and facilitated transition to subcutaneous therapy when necessary. PMID:21603515

  16. Integrating Multibody Simulation and CFD: toward Complex Multidisciplinary Design Optimization

    NASA Astrophysics Data System (ADS)

    Pieri, Stefano; Poloni, Carlo; Mühlmeier, Martin

    This paper describes the use of integrated multidisciplinary analysis and optimization of a race car model on a predefined circuit. The objective is the definition of the most efficient geometric configuration that can guarantee the lowest lap time. In order to carry out this study it has been necessary to interface the design optimization software modeFRONTIER with the following softwares: CATIA v5, a three dimensional CAD software, used for the definition of the parametric geometry; A.D.A.M.S./Motorsport, a multi-body dynamic simulation software; IcemCFD, a mesh generator, for the automatic generation of the CFD grid; CFX, a Navier-Stokes code, for the fluid-dynamic forces prediction. The process integration gives the possibility to compute, for each geometrical configuration, a set of aerodynamic coefficients that are then used in the multiboby simulation for the computation of the lap time. Finally an automatic optimization procedure is started and the lap-time minimized. The whole process is executed on a Linux cluster running CFD simulations in parallel.

  17. Take a Multidisciplinary, Team-based Approach on Elder Abuse.

    PubMed

    2016-07-01

    While EDs are well positioned to identify incidents of elder abuse, providers often miss the opportunity. Experts say providers find only one in every 24 cases, and that the pendulum must swing toward over-detection. Investigators acknowledge elder abuse is difficult to confirm, given that disease processes can explain some of the signs. Further, older adults are often reluctant to report abuse because they fear they will be removed from their homes or separated from their caregivers. Given the complexity involved with addressing the issue, investigators recommend EDs establish a multidisciplinary approach to the problem. Providing great care to a victim of elder abuse requires time and setting up a circumstance whereby one can actually communicate with the patient reliably and alone. While most states require providers to report suspected cases of elder abuse to Adult Protective Services, there is little evidence this requirement has incentivized more reports in the same way a similar requirement has prompted providers to report cases of suspected child abuse. Investigators advise ED leaders to train and empower every member of their team to identify potential signs of elder abuse. PMID:27439225

  18. Recent advances in integrated multidisciplinary optimization of rotorcraft

    NASA Technical Reports Server (NTRS)

    Adelman, Howard M.; Walsh, Joanne L.; Pritchard, Jocelyn I.

    1992-01-01

    A joint activity involving NASA and Army researchers at NASA LaRC to develop optimization procedures to improve the rotor blade design process by integrating appropriate disciplines and accounting for all of the important interactions among the disciplines is described. The disciplines involved include rotor aerodynamics, rotor dynamics, rotor structures, airframe dynamics, and acoustics. The work is focused on combining these five key disciplines in an optimization procedure capable of designing a rotor system to satisfy multidisciplinary design requirements. Fundamental to the plan is a three-phased approach. In phase 1, the disciplines of blade dynamics, blade aerodynamics, and blade structure are closely coupled while acoustics and airframe dynamics are decoupled and are accounted for as effective constraints on the design for the first three disciplines. In phase 2, acoustics is integrated with the first three disciplines. Finally, in phase 3, airframe dynamics is integrated with the other four disciplines. Representative results from work performed to date are described. These include optimal placement of tuning masses for reduction of blade vibratory shear forces, integrated aerodynamic/dynamic optimization, and integrated aerodynamic/dynamic/structural optimization. Examples of validating procedures are described.

  19. A Mechanism for Multidisciplinary Dialogue: The Memory & … Series

    PubMed Central

    Multhaup, Kristi S.; Denham, Scott; Kelly, Hilton; Lom, Barbara

    2011-01-01

    Neuroscientists have long explored the mechanisms of memory from molecular, physiological, cognitive, and social perspectives. Scholars from other disciplines such as history, sociology, literature, and cultural studies, that do not traditionally cross-pollinate ideas with neuroscientists, also study memory from a variety of angles. In this article, we describe the founding of a multidisciplinary discussion series in which faculty and staff from the arts, humanities, social sciences, and natural sciences come together to explain how memory is integral to their scholarship and teaching. After panelists from different disciplines present opening comments, the floor is open for discussion with the audience that includes students, staff, and community members, as well as other faculty. Each year the series is anchored by a keynote address by an eminent scholar engaged in cross-disciplinary memory research. We outline the benefits of such thematic discussion series, highlighting the synchrony with the academy’s increasing focus on interdisciplinarity, and on the need to train scholars to speak clearly about their work beyond their own disciplinary boundaries. More specifically, we focus on the need to train scientists to communicate with non-scientists. We have experienced success with this series and believe that the format could be adapted to a wide range of issues that cross disciplines (e.g., development, language, music, environmental studies). PMID:23626499

  20. Multidisciplinary Design Optimization on Conceptual Design of Aero-engine

    NASA Astrophysics Data System (ADS)

    Zhang, Xiao-bo; Wang, Zhan-xue; Zhou, Li; Liu, Zeng-wen

    2016-06-01

    In order to obtain better integrated performance of aero-engine during the conceptual design stage, multiple disciplines such as aerodynamics, structure, weight, and aircraft mission are required. Unfortunately, the couplings between these disciplines make it difficult to model or solve by conventional method. MDO (Multidisciplinary Design Optimization) methodology which can well deal with couplings of disciplines is considered to solve this coupled problem. Approximation method, optimization method, coordination method, and modeling method for MDO framework are deeply analyzed. For obtaining the more efficient MDO framework, an improved CSSO (Concurrent Subspace Optimization) strategy which is based on DOE (Design Of Experiment) and RSM (Response Surface Model) methods is proposed in this paper; and an improved DE (Differential Evolution) algorithm is recommended to solve the system-level and discipline-level optimization problems in MDO framework. The improved CSSO strategy and DE algorithm are evaluated by utilizing the numerical test problem. The result shows that the efficiency of improved methods proposed by this paper is significantly increased. The coupled problem of VCE (Variable Cycle Engine) conceptual design is solved by utilizing improved CSSO strategy, and the design parameter given by improved CSSO strategy is better than the original one. The integrated performance of VCE is significantly improved.

  1. Aifira: An ion beam facility for multidisciplinary research

    NASA Astrophysics Data System (ADS)

    Sorieul, S.; Alfaurt, Ph.; Daudin, L.; Serani, L.; Moretto, Ph.

    2014-08-01

    During the last decade, the CENBG (Centre d'Études Nucléaires de Bordeaux Gradignan) commissioned a new facility called AIFIRA (Applications Interdisciplinaires des Faisceaux d'ions en Région Aquitaine). It allowed the development of a multidisciplinary activity based on the "in-house" expertise of CENBG in ion beam analysis. The great flexibility offered by the five beam lines confers a lot of possibilities for chemical analysis and nuclear physics. Indeed, not only the macrobeam and the external beam lines provide the full set of IBA techniques for routine sample analysis but an additional beam line is devoted to the production of monoenergetic neutrons through the interaction of the incoming ion with selected targets. In addition, the two high-resolution microbeam lines are used for chemical analyses, 2D/3D imaging, and targeted cell irradiation. Besides, the combination of the nanobeam line flexibility, the uniqueness of the micro-irradiation design completed by the internal CENBG expertise confers a great specificity to AIFIRA in biomedical field. After a detailed technical overview of the platform, the article focuses on the two high-resolution lines as they tap most of the activity. Thus a quick overview of the most significant results concerning biomedical samples is proposed in order to highlight the analytical possibilities of AIFIRA microbeam lines. A summary of the development status of the micro-irradiation line is also done.

  2. a Multidisciplinary Analytical Framework for Studying Active Mobility Patterns

    NASA Astrophysics Data System (ADS)

    Orellana, D.; Hermida, C.; Osorio, P.

    2016-06-01

    Intermediate cities are urged to change and adapt their mobility systems from a high energy-demanding motorized model to a sustainable low-motorized model. In order to accomplish such a model, city administrations need to better understand active mobility patterns and their links to socio-demographic and cultural aspects of the population. During the last decade, researchers have demonstrated the potential of geo-location technologies and mobile devices to gather massive amounts of data for mobility studies. However, the analysis and interpretation of this data has been carried out by specialized research groups with relatively narrow approaches from different disciplines. Consequently, broader questions remain less explored, mainly those relating to spatial behaviour of individuals and populations with their geographic environment and the motivations and perceptions shaping such behaviour. Understanding sustainable mobility and exploring new research paths require an interdisciplinary approach given the complex nature of mobility systems and their social, economic and environmental impacts. Here, we introduce the elements for a multidisciplinary analytical framework for studying active mobility patterns comprised of three components: a) Methodological, b) Behavioural, and c) Perceptual. We demonstrate the applicability of the framework by analysing mobility patterns of cyclists and pedestrians in an intermediate city integrating a range of techniques, including: GPS tracking, spatial analysis, auto-ethnography, and perceptual mapping. The results demonstrated the existence of non-evident spatial behaviours and how perceptual features affect mobility. This knowledge is useful for developing policies and practices for sustainable mobility planning.

  3. Development of a Multidisciplinary, Multicampus Subspecialty Practice in Endocrine Cancers

    PubMed Central

    Bible, Keith C.; Smallridge, Robert C.; Morris, John C.; Molina, Julian R.; Suman, Vera J.; Copland, John A.; Rubin, Joseph; Menefee, Michael E.; Sideras, Kostandinos; Maples, William J.; McIver, Bryan; Fatourechi, Vahab; Hay, Ian; Foote, Robert L.; Garces, Yolanda I.; Kasperbauer, Jan L.; Thompson, Geoffrey B.; Grant, Clive S.; Richards, Melanie L.; Sebo, Thomas; Lloyd, Ricardo; Eberhardt, Norman L.; Reddi, Honey V.; Casler, John D.; Karlin, Nina J.; Westphal, Sydney A.; Richardson, Ronald L.; Buckner, Jan C.; Erlichman, Charles

    2012-01-01

    Purpose: Relative to more abundant neoplasms, endocrine cancers have been historically neglected, yet their incidence is increasing. We therefore sought to build interest in endocrine cancers, improve physician experience, and develop innovative approaches to treating patients with these neoplasms. Methods: Between 2005 and 2010, we developed a multidisciplinary Endocrine Malignancies Disease Oriented Group involving all three Mayo Clinic campuses (Rochester, MN; Jacksonville, FL; and Scottsdale, AZ). In response to higher demand at the Rochester campus, we sought to develop a Subspecialty Tumor Group and an Endocrine Malignancies Tumor Clinic within the Division of Medical Oncology. Results: The intended groups were successfully formed. We experienced difficulty in integration of the Mayo Scottsdale campus resulting from local uncertainty as to whether patient volumes would be sufficient to sustain the effort at that campus and difficulty in developing enthusiasm among clinicians otherwise engaged in a busy clinical practice. But these obstacles were ultimately overcome. In addition, with respect to the newly formed medical oncology subspecialty endocrine malignancies group, appointment volumes quadrupled within the first year and increased seven times within two years. The number of active therapeutic endocrine malignancies clinical trials also increased from one in 2005 to five in 2009, with all three Mayo campuses participating. Conclusion: The development of subspecialty tumor groups for uncommon malignancies represents an effective approach to building experience, increasing patient volumes and referrals, and fostering development of increased therapeutic options and clinical trials for patients afflicted with otherwise historically neglected cancers. PMID:22942830

  4. Deep brain stimulation for vocal tremor: a comprehensive, multidisciplinary methodology.

    PubMed

    Ho, Allen L; Erickson-Direnzo, Elizabeth; Pendharkar, Arjun V; Sung, Chih-Kwang; Halpern, Casey H

    2015-06-01

    Tremulous voice is a characteristic feature of a multitude of movement disorders, but when it occurs in individuals diagnosed with essential tremor, it is referred to as essential vocal tremor (EVT). For individuals with EVT, their tremulous voice is associated with significant social embarrassment and in severe cases may result in the discontinuation of employment and hobbies. Management of EVT is extremely difficult, and current behavioral and medical interventions for vocal tremor result in suboptimal outcomes. Deep brain stimulation (DBS) has been proposed as a potential therapeutic avenue for EVT, but few studies can be identified that have systematically examined improvements in EVT following DBS. The authors describe a case of awake bilateral DBS targeting the ventral intermediate nucleus for a patient suffering from severe voice and arm tremor. They also present their comprehensive, multidisciplinary methodology for definitive treatment of EVT via DBS. To the authors' knowledge, this is the first time comprehensive intraoperative voice evaluation has been used to guide microelectrode/stimulator placement, as well as the first time that standard pre- and post-DBS assessments have been conducted, demonstrating the efficacy of this tailored DBS approach. PMID:26030706

  5. Multidisciplinary approaches to understanding collective cell migration in developmental biology

    PubMed Central

    Schumacher, Linus J.; Kulesa, Paul M.; McLennan, Rebecca; Baker, Ruth E.; Maini, Philip K.

    2016-01-01

    Mathematical models are becoming increasingly integrated with experimental efforts in the study of biological systems. Collective cell migration in developmental biology is a particularly fruitful application area for the development of theoretical models to predict the behaviour of complex multicellular systems with many interacting parts. In this context, mathematical models provide a tool to assess the consistency of experimental observations with testable mechanistic hypotheses. In this review, we showcase examples from recent years of multidisciplinary investigations of neural crest cell migration. The neural crest model system has been used to study how collective migration of cell populations is shaped by cell–cell interactions, cell–environmental interactions and heterogeneity between cells. The wide range of emergent behaviours exhibited by neural crest cells in different embryonal locations and in different organisms helps us chart out the spectrum of collective cell migration. At the same time, this diversity in migratory characteristics highlights the need to reconcile or unify the array of currently hypothesized mechanisms through the next generation of experimental data and generalized theoretical descriptions. PMID:27278647

  6. Automatic differentiation of advanced CFD codes for multidisciplinary design

    SciTech Connect

    Bischof, C.; Corliss, G.; Griewank, A. ); Green, L.; Haigler, K.; Newman, P. . Langley Research Center)

    1992-01-01

    Automated multidisciplinary design of aircraft and other flight vehicles requires the optimization of complex performance objectives with respect to a number of design parameters and constraints. The effect of these independent design variables on the system performance criteria can be quantified in terms of sensitivity derivatives which must be calculated and propagated by the individual discipline simulation codes. Typical advanced CFD analysis codes do not provide such derivatives as part of a flow solution; these derivatives are very expensive to obtain by divided (finite) differences from perturbed solutions. It is shown here that sensitivity derivatives can be obtained accurately and efficiently using the ADIFOR source translator for automatic differentiation. In particular, it is demonstrated that the 3-D, thin-layer Navier-Stokes, multigrid flow solver called TLNS3D is amenable to automatic differentiation in the forward mode even with its implicit iterative solution algorithm and complex turbulence modeling. It is significant that using computational differentiation, consistent discrete nongeometric sensitivity derivatives have been obtained from an aerodynamic 3-D CFD code in a relatively short time, e.g. O(man-week) not O(man-year).

  7. Automatic differentiation of advanced CFD codes for multidisciplinary design

    SciTech Connect

    Bischof, C.; Corliss, G.; Griewank, A.; Green, L.; Haigler, K.; Newman, P.

    1992-12-31

    Automated multidisciplinary design of aircraft and other flight vehicles requires the optimization of complex performance objectives with respect to a number of design parameters and constraints. The effect of these independent design variables on the system performance criteria can be quantified in terms of sensitivity derivatives which must be calculated and propagated by the individual discipline simulation codes. Typical advanced CFD analysis codes do not provide such derivatives as part of a flow solution; these derivatives are very expensive to obtain by divided (finite) differences from perturbed solutions. It is shown here that sensitivity derivatives can be obtained accurately and efficiently using the ADIFOR source translator for automatic differentiation. In particular, it is demonstrated that the 3-D, thin-layer Navier-Stokes, multigrid flow solver called TLNS3D is amenable to automatic differentiation in the forward mode even with its implicit iterative solution algorithm and complex turbulence modeling. It is significant that using computational differentiation, consistent discrete nongeometric sensitivity derivatives have been obtained from an aerodynamic 3-D CFD code in a relatively short time, e.g. O(man-week) not O(man-year).

  8. Teaching multidisciplinary environmental science in a wetland setting

    USGS Publications Warehouse

    Panno, S.V.; Hackley, Keith C.; Nuzzo, V.A.

    1998-01-01

    High-school students from across the country came to the Illinois State Geological Survey (ISGS) to assist in field research for two weeks in July, 1994, as part of The Johns Hopkins University Center for Talented Youth Summer Experience Program. During the research project at the ISGS, students were exposed to a multidisciplinary scientific investigation where geology, hydrogeology, ground-water chemistry, and plant biology could be directly observed and used to study the potentially destructive effects of nearby road and house construction on a fen-wetland complex. Experienced researchers provided classroom and field instruction to the students prior to leading the field investigations. Following field work, the students returned to the ISGS laboratories where they assisted with the chemical analysis of ground-water samples and compiled and interpreted their data. The students wrote up their results in standard scientific report format and gave oral presentations covering various aspects of the project to an audience of ISGS scientists and guests. The results of their work, which showed changes in the wetland's plant biodiversity resulting from urban development within the watershed, will provide data needed for the preservation of biodiversity in these and other wetlands.

  9. [Multidisciplinary approach to the treatment of patients with diabetic foot].

    PubMed

    Pityk, O I; Prasol, V O; Boĭko, V V; Babynkin, A B

    2013-12-01

    Diabetic foot (DF) is considered now the main cause of amputations of lower limbs. The analysis of the results of 266 percutaneous endovascular interventions (EV) performed during 2008-2012 in 245 patients with ischemic and neuroishemic DF was carried out. 76% of the patients underwent percutaneous balloon angioplasty (PBA), 24%--PBA + stenting. 91% of EV were technically successful. In 95% of the patients who achieved recovery of the main flow in the occluded arterial segment, clinical improvement was observed in the form of disappearance of the pain and start of the healing of ulcer-necrotic lesions of the foot. The main causes of technical failure (9%) were impossibility to pass through long calcified occlusions of infrainguinal arteries. The complication rate was 10.5%, major amputation--5.2%, mortality--0.8%. Long-term results were shown by the combined rate of amputation-free survival after 1, 3 and 5 years follow-up which made up respectively, 86%, 70% and 43%. EV is an effective treatment for patients with DF and an integrated multidisciplinary approach to achieve high limb salvage rates in the long-term period. PMID:25726682

  10. Recent advances in multidisciplinary management of hepatocellular carcinoma

    PubMed Central

    Gomaa, Asmaa I; Waked, Imam

    2015-01-01

    The incidence of hepatocellular carcinoma (HCC) is increasing, and it is currently the second leading cause of cancer-related death worldwide. Potentially curative treatment options for HCC include resection, transplantation, and percutaneous ablation, whereas palliative treatments include trans-arterial chemoembolization (TACE), radioembolization, and systemic treatments. Due to the diversity of available treatment options and patients’ presentations, a multidisciplinary team should decide clinical management of HCC, according to tumor characteristics and stage of liver disease. Potentially curative treatments are suitable for very-early- and early-stage HCC. However, the vast majority of HCC patients are diagnosed in later stages, where the tumor characteristics or progress of liver disease prevent curative interventions. For patients with intermediate-stage HCC, TACE and radioembolization improve survival and are being evaluated in addition to potentially curative therapies or with systemic targeted therapy. There is currently no effective systemic chemotherapy, immunologic, or hormonal therapy for HCC, and sorafenib is the only approved molecular-targeted treatment for advanced HCC. Other targeted agents are under investigation; trials comparing new agents in combination with sorafenib are ongoing. Combinations of systemic targeted therapies with local treatments are being evaluated for further improvements in HCC patient outcomes. This article provides an updated and comprehensive overview of the current standards and trends in the treatment of HCC. PMID:25866604

  11. Bearberry identification by a multidisciplinary study on commercial raw materials.

    PubMed

    Gallo, Francesca Romana; Multari, Giuseppina; Pagliuca, Giordana; Panusa, Alessia; Palazzino, Giovanna; Giambenedetti, Massimo; Petitto, Valentina; Nicoletti, Marcello

    2013-04-01

    Herbal species different from the official bearberry, Arctostaphylos uva-ursi, are sold through conventional markets and also through non-controlled Internet websites, putting consumer safety at risk owing to the lack of quality control. Recently, Arctostaphylos pungens has become one of the most used species as a raw material for herbal medicines and dietary supplements in the place of official bearberry, a plant used for the treatment of various urinary disorders. A fingerprint identification based on an integrated application of different analytical techniques (HPTLC, NMR, HPLC-DAD and LC-ESI-MS) is here described to distinguish A. uva-ursi from A. pungens. The HPTLC and HPLC-DAD fingerprints resulted the simplest methods to differentiate the two species, whereas LC-ESI-MS was more useful to quantify arbutin, the main component of bearberry, and to evaluate its different content in the two species. This multidisciplinary study showed for the first time a specific phytochemical fingerprint of the new species A. pungens. PMID:22712621

  12. [Multidisciplinary approach of hip fractures based on Hungarian data].

    PubMed

    Juhász, Krisztina; Turchányi, Béla; Mintál, Tibor; Somogyi, Péter

    2016-09-01

    Hip fractures are described by increased mortality, loss of quality of life, functional decline and burden of diseases. They show a growing number worldwide. The aim of the present study is to summarise the existing data on the incidence, mortality, complications and rehabilitation of hip fractures, which relevance is reported only by few studies. To reduce mortality and complications of hip fractures the authors emphasize the importance of primary treatment within 12 hours, appropriate selection of surgical methods corresponding to the fracture type after the assessment of femoral head viability, vitamin D supplementation, same conditions for primary treatment during everyday of the week, and an adequate acute treatment and rehabilitation for patient's general health status. In the future integrated processing of multidisciplinary results of hip fractures based on Hungarian data can support the development of efficient treatment and prevention strategies, which can be advantageous for the patient, families, health care system, and the society, too, by the reduction of costly complications of hip fracture healing and mortality. Orv. Hetil., 2016, 157(37), 1469-1475. PMID:27615197

  13. The European Mobile System (EMS)

    NASA Technical Reports Server (NTRS)

    Jongejans, A.; Rogard, R.; Mistretta, I.; Ananasso, F.

    1993-01-01

    The European Space Agency is presently procuring an L band payload in order to promote a regional European L band system coping with the specific needs of the European market. The payload, and the two communications systems to be supported, are described below. The potential market for EMS in Europe is discussed.

  14. Analysis of general population surveys with regard to comparable estimates of disability and its correlates across selected European surveys.

    PubMed

    Andronache, Adrian Stefan; Alvarez, Ana Sabela; Ajovalasit, Daniela; Cerniauskaite, Milda; Koutsogeorgou, Eleni; Quintas, Rui; Leonardi, Matilde

    2012-02-01

    This article presents a methodology developed by the Multidisciplinary Research on Health and Disability in Europe project researchers for the retrieval of information about disability using the conceptual framework of the International Classification of Functioning, Disability and Health. A comprehensive review and analysis of European surveys was performed and it is presented here briefly. Recommendations and guidelines for future statistical studies and development of disability surveys are provided. The methodology proposed shows the utility and feasibility of the ICF in research. PMID:22193321

  15. Multidisciplinary sleep centers: strategies to improve care of sleep disorders patients.

    PubMed

    Shelgikar, Anita Valanju; Durmer, Jeffrey S; Joynt, Karen E; Olson, Eric J; Riney, Heidi; Valentine, Paul

    2014-06-15

    Current emphasis on patient outcomes within sleep medicine, with a particular focus on quality improvement and contained costs, calls for sleep specialists to develop innovative models for long-term care and management of sleep disorders patients. Multidisciplinary sleep centers can facilitate highest-quality care that is timely and cost-effective. Effective resource use in a multidisciplinary sleep center can help minimize fragmentation of care, reduce effort duplication, and control costs. Proposed strategies to help achieve a balance between quality of care and cost-effectiveness include: (1) multidisciplinary specialty clinics, (2) optimized use of information technology, and (3) adoption of reliable performance measures. PMID:24932153

  16. A systematic evaluation of a multidisciplinary social work-lawyer elder mistreatment intervention model.

    PubMed

    Rizzo, Victoria M; Burnes, David; Chalfy, Amy

    2015-01-01

    This study introduces a conceptually based, systematic evaluation process employing multivariate techniques to evaluate a multidisciplinary social work-lawyer intervention model (JASA-LEAP). Logistic regression analyses were used with a random sample of case records (n = 250) from three intervention sites. Client retention, program fidelity, and exposure to multidisciplinary services were significantly related to reduction in mistreatment risk at case closure. Female gender, married status, and living with perpetrator significantly predicted unfavorable outcomes. This study extends the elder mistreatment program evaluation literature beyond descriptive/bivariate evaluation strategies. Findings suggest that a multidisciplinary social work-lawyer elder mistreatment intervention model is a successful approach. PMID:24965802

  17. Multidisciplinary Design, Analysis, and Optimization Tool Development Using a Genetic Algorithm

    NASA Technical Reports Server (NTRS)

    Pak, Chan-gi; Li, Wesley

    2009-01-01

    Multidisciplinary design, analysis, and optimization using a genetic algorithm is being developed at the National Aeronautics and Space Administration Dryden Flight Research Center (Edwards, California) to automate analysis and design process by leveraging existing tools to enable true multidisciplinary optimization in the preliminary design stage of subsonic, transonic, supersonic, and hypersonic aircraft. This is a promising technology, but faces many challenges in large-scale, real-world application. This report describes current approaches, recent results, and challenges for multidisciplinary design, analysis, and optimization as demonstrated by experience with the Ikhana fire pod design.!

  18. Education and European integration

    NASA Astrophysics Data System (ADS)

    Lowe, John

    1992-11-01

    The main purpose of this article is to discuss the implications for education and training of the movement towards integration in Europe in the historic context of the creation of a single market within the European Community (EC) and the end of the Communist regimes in Central and Eastern Europe. The experience of the EC is used to illustrate trends and problems in the development of international cooperation in education and training. Common concerns and priorities throughout the new Europe are then identified and discussed. These include the pursuit of quality in schooling, efforts to serve the interests of disadvantaged learners, and the treatment of European Studies in the curriculum, including the improvement of the teaching of foreign languages.

  19. Telemedicine and European law.

    PubMed

    Callens, Stefaan

    2003-01-01

    A Directive of the European Union was first published in 2000, which dealt with telemedicine as part of its provisions. This E-Commerce Directive, as it became known, was subjected to further study which revealed some problems relative to the practice of telemedicine. Among the subjects discussed in this paper are those of privacy, data protection, free movement of services, the impact of electronic communication and ethical issues. PMID:15074761

  20. The European Spallation Source

    SciTech Connect

    Peggs, S; Eshraqi, M; Hahn, H; Jansson, A; Lindroos, M; Ponton, A; Rathsman, K; Trahern, G; Bousso, S; Calaga, R; Devanz, G; Duperrier, R D; Eguia, J; Gammino, S; Moller, S P; Oyon, C; Ruber, R.J.M.Y.; Satogata, T

    2011-03-01

    The European Spallation Source (ESS) is a 5 MW, 2.5 GeV long pulse proton linac, to be built and commissioned in Lund, Sweden. The Accelerator Design Update (ADU) project phase is under way, to be completed at the end of 2012 by the delivery of a Technical Design Report. Improvements to the 2003 ESS design will be summarised, and the latest design activities will be presented.

  1. The FUTUREVOLC Supersite's e-Infrastructure - A multidisciplinary data hub and data service for Icelandic Volcanoes

    NASA Astrophysics Data System (ADS)

    Vogfjörd, Kristín S.; Sigmundsson, Freysteinn; Sverrisson, Sverrir Th.; Sigurdsson, Sigurdur F.; Ófeigsson, Benedikt G.; Arnarsson, Ólafur S.; Kristinsson, Ingvar; Ilyinskaya, Evgenia; Oddsdóttir, Thorarna Ýr; Bergsveinsson, Sölvi Th.; Hjartansson, Kristján R.

    2014-05-01

    The FUTUREVOLC volanological supersite will establish a data hub and dataservice, where researchers, hazard managers and other stake holders can freely obtain access to multidisciplinary data and products on activity, unrest and eruptions at Icelandic volcanoes. The supersite is firmly founded on close interaction between the main Icelandic volcanological research and monitoring institutions, in coordination with expertise from European researchers participating in FUTUREVOLC. The hub is located at the Icelandic Meteorological Office (IMO), an institution responsible for monitoring and archiving data on all natural hazards in Iceland and, which also has a mandate as the state volcano observatory. This association will ensure a long-term sustainable data service. The data accessible at the hub include in-situ and space-based observations, products and models from all the relevant disciplines contributing to volcanological research and local as well as cross-border hazard management, i.e. Earth sciences, atmospheric science, hydrology, remote sensing and space science. Access to the data will be in compliance with the access policy of the GEO (Group on Earth Observations), providing registered users with easy and timely access to data and products of documented quality. This commitment has already led to the acceptance of FUTUREVOLC as a permanent geohazard supersite by CEOS (Committee on Earth Observation Satellites), which will ensure access to additional satellite data and products on Icelandic volcanoes. To facilitate services to seismological data at the supersite hub, the IMO is reconstructing its existing data base and utilizing the SeisComp3 software to manage waveform and parameter data. The accompanying ArcLink component will be used to provide access to event data and waveforms. Access to GPS data will be provided by the GSAC web service which has been installed at the IMO through collaboration with UNAVCO. If appropriate, the format and data base

  2. Occupational skin diseases: options for multidisciplinary networking in preventive medicine

    PubMed Central

    John, Swen Malte

    2008-01-01

    Occupational dermatoses (OD) have topped the list of occupational diseases in Germany for years. Presently, approximately 16,000 new OD cases are officially reported to public statutory employers’ liability insurance bodies, each year. The disease burden is high not only for individuals but also for society as a whole. Estimated annual economic costs in Germany due to sick-leave and lack of productivity due to OD are more than 1.5 billion euros. Thus, in recent years, various pilot initiatives aiming to improve prevention of occupational skin diseases (of various degrees of severity) have been developed and recently evaluated in Osnabrück. These activities have been funded by statutory employers’ liability insurance schemes. Concepts underpinning these initiatives include multidisciplinary skin protection teaching programs for various high-risk professions, which turned out to be pivotal for the success of these projects. A corollary of this work is a nationwide multi-step intervention approach currently implemented by the public statutory insurance system. This approach offers quick preventive help for all levels of severity of OD. These nation-wide activities are accompanied by a national Prevention Campaign: Skin 2007/2008 (Figure 1 (Fig. 1)), which focuses mainly on primary prevention. Despite the high prevalence of OD and its poor prognosis, little is known about the molecular mechanisms underlying individual susceptibility to develop chronic irritant dermatitis. Skin irritation tests are thus far of only limited value. Presently, our institution, in collaboration with Amsterdam universities, focuses on immunogenetic risk factors potentially involved in individual susceptibility to OD in order to improve pre-employment counseling and predictive skin testing. For early secondary prevention, the so-called dermatologist’s procedure was recently up-dated in order to provide more rapid dermatological consultation. Additionally, combined outpatient

  3. Clean wing airframe noise modeling for multidisciplinary design and optimization

    NASA Astrophysics Data System (ADS)

    Hosder, Serhat

    transport wing at realistic approach conditions. The twist distribution of the baseline wing was changed to obtain a modified wing which was used to investigate the effect of the twist on the trailing edge noise. An example study with NACA 0012 and NACA 0009 airfoils demonstrated a reduction in the trailing edge noise by decreasing the thickness ratio and the lift coefficient, while increasing the chord length to keep the same lift at a constant speed. Both two- and three-dimensional studies demonstrated that the trailing edge noise remains almost constant at low lift coefficients and gets larger at higher lift values. The increase in the noise metric can be dramatic when there is separation on the wing. Three-dimensional effects observed in the wing cases indicate the importance of calculating the noise metric with a characteristic velocity and length scale that vary along the span. The twist change does not have a significant effect on the noise at low lift coefficients, however it may give significant noise reduction at higher lift values. The results obtained in this study show the importance of the lift coefficient, CL, on the airframe noise of a clean wing and favors having a larger wing area to reduce the CL for minimizing the noise. The results also point to the fact that the noise reduction studies should be performed in a multidisciplinary design and optimization framework, since many of the parameters that change the trailing edge noise also affect the other aircraft design requirements. It's hoped that the noise metric developed here can aid in such multidisciplinary design and optimization studies.

  4. Changing Climates @ Colorado State: 100 (Multidisciplinary) Views of Climate Change

    NASA Astrophysics Data System (ADS)

    Campbell, S.; Calderazzo, J.; Changing Climates, Cmmap Education; Diversity Team

    2011-12-01

    We would like to talk about a multidisciplinary education and outreach program we co-direct at Colorado State University, with support from an NSF-funded STC, CMMAP, the Center for Multiscale Modeling of Atmospheric Processes. We are working to raise public literacy about climate change by providing information that is high quality, up to date, thoroughly multidisciplinary, and easy for non-specialists to understand. Our primary audiences are college-level students, their teachers, and the general public. Our motto is Climate Change is Everybody's Business. To encourage and help our faculty infuse climate-change content into their courses, we have organized some 115 talks given by as many different speakers-speakers drawn from 28 academic departments, all 8 colleges at CSU, and numerous other entities from campus, the community, and farther afield. We began with a faculty-teaching-faculty series and then broadened our attentions to the whole campus and surrounding community. Some talks have been for narrowly focused audiences such as extension agents who work on energy, but most are for more eclectic groups of students, staff, faculty, and citizens. We count heads at most events, and our current total is roughly 6,000. We have created a website (http://changingclimates.colostate.edu) that includes videotapes of many of these talks, short videos we have created, and annotated sources that we judge to be accurate, interesting, clearly written, and aimed at non-specialists, including books, articles and essays, websites, and a few items specifically for college teachers (such as syllabi). Pages of the website focus on such topics as how the climate works / how it changes; what's happening / what might happen; natural ecosystems; agriculture; impacts on people; responses from ethics, art, literature; communication; daily life; policy; energy; and-pulling all the pieces together-the big picture. We have begun working on a new series of very short videos that can be

  5. Draix multidisciplinary observatory for water and sediment processes

    NASA Astrophysics Data System (ADS)

    Le Bouteiller, C.; Mathys, N.; Liébault, F.; Klotz, S.

    2013-12-01

    Over the last decades, much progress has been done in the modeling and conceptualizing of surface processes. Testing theories and models requires field data, and possibly long-term time series. Here we present a 30-year old field observatory dedicated to water and sediment fluxes in the French Alps. Draix observatory is located in a badland area of the French Alps (shale lithology), and includes several subcatchments which differ in size (0.001 to 1 km2) and vegetation coverage (bare soil or forest). Climate is mountainous and Mediterranean, characterized with summer storm-induced floods and winter frost. Data collected includes climatic data (rainfall, temperature) and water and sediment fluxes (discharge at the outlet of each subcatchment, suspended load and bedload fluxes). High frequency monitoring (minute/hour) is used to capture flood dynamics. Some soil hydraulic and geophysical properties, lidar scans and vegetation maps are also available. The combination of an erodible badland morphology and tough climatic conditions induces very high erosion rates and sediment yield (up to 70 tons/ha/yr). Observed erosion processes include landslides, small-scale debris flows, gully formation, weathering on the slopes and in the riverbeds, hyperconcentrated flows and in-transport sediment abrasion. The sediment response is highly non-linear with a strong seasonal pattern of storage and scour in the bed. Current research on Draix observatory is multidisciplinary and involves hydraulic engineers, hydrologists, geomorphologists, soil scientists and restoration ecologists. Fast rates of geomorphic changes, well-constrained sediment budgets and long data series are some of the advantages of this site for the study of earth surface processes. Our data is available for the community and we welcome everyone who is interested in collaborating on it.

  6. Benefits of multidisciplinary teamwork in the management of breast cancer

    PubMed Central

    Taylor, Cath; Shewbridge, Amanda; Harris, Jenny; Green, James S

    2013-01-01

    The widespread introduction of multidisciplinary team (MDT)-work for breast cancer management has in part evolved due to the increasing complexity of diagnostic and treatment decision-making. An MDT approach aims to bring together the range of specialists required to discuss and agree treatment recommendations and ongoing management for individual patients. MDTs are resource-intensive yet we lack strong (randomized controlled trial) evidence of their effectiveness. Clinical consensus is generally favorable on the benefits of effective specialist MDT-work. Many studies have shown the benefits of receiving treatment from a specialist center, and evidence continues to accrue from comparative studies of clinical benefits of an MDT approach, including improved survival. Patients’ views of the MDT model of decision-making (and in particular its impact on involvement in decisions about their care) have been under-researched. Barriers to effective teamwork and poor decision-making include excessive caseload, low attendance at meetings, lack of leadership, poor communication, role ambiguity, and failure to consider patients’ holistic needs. Breast cancer nurses have a key role in relation to assessing holistic needs, and their specialist contribution has also been associated with improved patient experience and quality of life. This paper examines the evidence for the benefits of MDT-work, in particular for breast cancer. Evidence is considered within a context of growing cancer incidence at a time of increased financial restraint, and it may now be important to reevaluate the structure and models of MDT-work to ensure that MDTs are an efficient use of resources. PMID:24648761

  7. Characterizing User Communities of Large Multi-Disciplinary Research Facilities

    NASA Astrophysics Data System (ADS)

    Ludwig, K. A.

    2012-12-01

    Large-scale multi-user research facilities are a critical component of the federal science and engineering research enterprise. Developing infrastructure for multidisciplinary research requires large investments over long periods of time and typically involves partnerships across many institutions. Consequently, multiple policy questions surround federal investments in large research facilities including what is the best way to maximize scientific productivity? How should investments in infrastructure be balanced with support for individual or small group research? For many facilities, the answers to these questions become focused on the activities of the users: the individuals who are interacting with the facility for furthering scientific research and/or education. This independent study provides the first known analysis of facility utilization. Four facilities supported by the National Science Foundation (NSF) are used as case studies to create a conceptual framework for characterizing facility utilization, to examine changes in facility use over time, and to define how lessons learned can be applied to facility management and planning. Results show that there is a broad spectrum of users who interact with each facility in different ways and that for some facilities, unanticipated users are driving new areas of research. This work also shows that cyberinfrastructure-enabled facilities are experiencing rapid increases in data use and in some cases, the next generation of facility users appears to be developing new skills for working in an increasingly data-intensive research environment. Characterizing and quantifying large facility use will likely become increasingly important as the federal government continues to focus on developing metrics and evaluation tools for its investments in science and engineering research. This work establishes a foundation for assessing facility utilization and shows that this area is ripe for future work that may include portfolio

  8. Surgeons' views on multi-disciplinary breast meetings.

    PubMed

    Macaskill, E J; Thrush, S; Walker, E M; Dixon, J M

    2006-05-01

    The aim of this study was to assess surgeons' views and their current commitments to multi-disciplinary breast meetings (MDMs). Two hundred and fifty questionnaires were sent out to registered members of the British Association of Surgical Oncology. Hundred and fifty-three were returned (reply rate 61.2%), of which 136 were suitable for analysis. All those who replied were involved in MDMs. 80.9% held MDMs once a week. Only 28% of MDMs were held during a protected session. Over 95% of surgeons and breast care nurses were present for the whole meeting. Radiologists and pathologists were present for the whole meeting in 90-95% of cases. In contrast, clinical oncologists were present for the whole MDM in 70% of cases and medical oncologists attended the whole meeting in only 44.1% of cases. There was variability in which patients were discussed in MDMs, and in many centres not all patients with cancer were discussed before surgery. Suggestions for improvement of MDMs included more time on protected sessions (72.8% in favour), time to prepare for meetings (29% in favour), allocation of a designated co-ordinator (30.9% in favour) and attendance of oncologists for the whole meeting (over 35% in favour). The majority of Breast MDMs were held at breakfast, lunch or the evening. There was variable attendance with a significant percentage of both clinical and medical oncologists not being present for the whole meeting. A quarter of units did not discuss patients with breast cancer before operation. This study shows that there is a need to improve provision for MDMs and to produce guidelines for these meetings. PMID:16516461

  9. A multidisciplinary optimization method for designing boundary layer ingesting inlets

    NASA Astrophysics Data System (ADS)

    Rodriguez, David Leonard

    2001-07-01

    The Blended-Wing-Body is a conceptual aircraft design with rear-mounted, over-wing engines. Two types of engine installations have been considered for this aircraft. One installation is quite conventional with podded engines mounted on pylons. The other installation has partially buried engines with boundary layer ingesting inlets. Although ingesting the low-momentum flow in a boundary layer can improve propulsive efficiency, poor inlet performance can offset and even overwhelm this potential advantage. For both designs, the tight coupling between the aircraft aerodynamics and the propulsion system poses a difficult design integration problem. This dissertation presents a design method that solves the problem using multidisciplinary optimization. A Navier-Stokes flow solver, an engine analysis method, and a nonlinear optimizer are combined into a design tool that correctly addresses the tight coupling of the problem. The method is first applied to a model 2D problem to expedite development and thoroughly test the scheme. The low computational cost of the 2D method allows for several inlet installations to be optimized and analyzed. The method is then upgraded by using a validated 3D Navier-Stokes solver. The two candidate engine installations are analyzed and optimized using this inlet design method. The method is shown to be quite effective at integrating the propulsion and aerodynamic systems of the Blend-Wing-Body for both engine installations by improving overall performance and satisfying any specified design constraints. By comparing the two optimized designs, the potential advantages of ingesting boundary layer flow for this aircraft are demonstrated.

  10. [Subarachnoid hemorrhage: epidemiology, social impact and a multidisciplinary approach].

    PubMed

    Ingelmo Ingelmo, I; Fàbregas Julià, N; Rama-Maceiras, P; Hernández-Palazón, J; Rubio Romero, R; Carmona Aurioles, J

    2010-12-01

    Cerebrovascular disease, whether ischemic or hemorrhagic, is a worldwide problem, representing personal tragedy, great social and economic consequences, and a heavy burden on the health care system. Estimated to be responsible for up to 10% of mortality in industrialized countries, cerebrovascular disease also affects individuals who are still in the workforce, with consequent loss of productive years. Subarachnoid hemorrhage (SAH) is a type of cerebrovascular accident that leads to around 5% of all strokes. SAH is most often due to trauma but may also be spontaneous, in which case the cause may be a ruptured intracranial aneurysm (80%) or arteriovenous malformation or any other abnormality of the blood or vessels (20%). Although both the diagnosis and treatment of aneurysmal SAH has improved in recent years, related morbidity and mortality remains high: 50% of patients die from the initial hemorrhage or later complications. If patients whose brain function is permanently damaged are added to the count, the percentage of cases leading to severe consequences rises to 70%. The burden of care of patients who are left incapacitated by SAH falls to the family or to private and public institutions. The economic cost is considerable and the loss of quality of life for both the patient and the family is great. Given the magnitude of this problem, the provision of adequate prophylaxis is essential; also needed are organizational models that aim to reduce mortality as well as related complications. Aneurysmal SAH is a condition which must be approached in a coordinated, multidisciplinary way both during the acute phase and throughout rehabilitation in order to lower the risk of unwanted outcomes. PMID:21298906

  11. Multidisciplinary life cycle metrics and tools for green buildings.

    PubMed

    Helgeson, Jennifer F; Lippiatt, Barbara C

    2009-07-01

    Building sector stakeholders need compelling metrics, tools, data, and case studies to support major investments in sustainable technologies. Proponents of green building widely claim that buildings integrating sustainable technologies are cost effective, but often these claims are based on incomplete, anecdotal evidence that is difficult to reproduce and defend. The claims suffer from 2 main weaknesses: 1) buildings on which claims are based are not necessarily "green" in a science-based, life cycle assessment (LCA) sense and 2) measures of cost effectiveness often are not based on standard methods for measuring economic worth. Yet, the building industry demands compelling metrics to justify sustainable building designs. The problem is hard to solve because, until now, neither methods nor robust data supporting defensible business cases were available. The US National Institute of Standards and Technology (NIST) Building and Fire Research Laboratory is beginning to address these needs by developing metrics and tools for assessing the life cycle economic and environmental performance of buildings. Economic performance is measured with the use of standard life cycle costing methods. Environmental performance is measured by LCA methods that assess the "carbon footprint" of buildings, as well as 11 other sustainability metrics, including fossil fuel depletion, smog formation, water use, habitat alteration, indoor air quality, and effects on human health. Carbon efficiency ratios and other eco-efficiency metrics are established to yield science-based measures of the relative worth, or "business cases," for green buildings. Here, the approach is illustrated through a realistic building case study focused on different heating, ventilation, air conditioning technology energy efficiency. Additionally, the evolution of the Building for Environmental and Economic Sustainability multidisciplinary team and future plans in this area are described. PMID:20050028

  12. Variable-Complexity Multidisciplinary Optimization on Parallel Computers

    NASA Technical Reports Server (NTRS)

    Grossman, Bernard; Mason, William H.; Watson, Layne T.; Haftka, Raphael T.

    1998-01-01

    This report covers work conducted under grant NAG1-1562 for the NASA High Performance Computing and Communications Program (HPCCP) from December 7, 1993, to December 31, 1997. The objective of the research was to develop new multidisciplinary design optimization (MDO) techniques which exploit parallel computing to reduce the computational burden of aircraft MDO. The design of the High-Speed Civil Transport (HSCT) air-craft was selected as a test case to demonstrate the utility of our MDO methods. The three major tasks of this research grant included: development of parallel multipoint approximation methods for the aerodynamic design of the HSCT, use of parallel multipoint approximation methods for structural optimization of the HSCT, mathematical and algorithmic development including support in the integration of parallel computation for items (1) and (2). These tasks have been accomplished with the development of a response surface methodology that incorporates multi-fidelity models. For the aerodynamic design we were able to optimize with up to 20 design variables using hundreds of expensive Euler analyses together with thousands of inexpensive linear theory simulations. We have thereby demonstrated the application of CFD to a large aerodynamic design problem. For the predicting structural weight we were able to combine hundreds of structural optimizations of refined finite element models with thousands of optimizations based on coarse models. Computations have been carried out on the Intel Paragon with up to 128 nodes. The parallel computation allowed us to perform combined aerodynamic-structural optimization using state of the art models of a complex aircraft configurations.

  13. Physics Education in a Multidisciplinary Materials Research Environment

    NASA Astrophysics Data System (ADS)

    Doyle, W. D.

    1997-03-01

    The MINT Center, an NSF Materials Research Science and Engineering Center, is a multidisciplinary research program focusing on materials information storage. It involves 17 faculty, 10 post-doctoral fellows and 25 graduate students from six academic programs including Physics, Chemistry, Materials Science, Metallurgical and Materials Engineering, Electric al Engineering and Chemical Engineering, whose research is supported by university, federal and industrial funds. The research facilities (15,000 ft^2) which include faculty and student offices are located in one building and are maintained by the university and the Center at no cost to participating faculty. The academic requirements for the students are determined by the individual departments along relatively rigid, traditional grounds although several materials and device courses are offered for students from all departments. Within the Center, participants work in teams assigning responsibilities and sharing results at regularly scheduled meetings. Bi-weekly research seminars for all participants provide excellent opportunities for students to improve their communication skills and to receive critical input from a large, diverse audience. Strong collaboration with industrial partners in the storage industry supported by workshops, research reviews, internships, industrial visitors and participation in industry consortia give students a broader criteria for self-evaluation, higher motivation and excellent career opportunities. Physics students, because of their rigorous basic training, are an important element in a strong materials sciences program, but they often are deficient in the behavior and characterization of real materials. The curriculum for physics students should be broadened to prepare them fully for a rewarding career in this emerging discipline.

  14. Inception of a national multidisciplinary registry for stereotactic radiosurgery.

    PubMed

    Sheehan, Jason P; Kavanagh, Brian D; Asher, Anthony; Harbaugh, Robert E

    2016-01-01

    Stereotactic radiosurgery (SRS) represents a multidisciplinary approach to the delivery of ionizing high-dose radiation to treat a wide variety of disorders. Much of the radiosurgical literature is based upon retrospective single-center studies along with a few randomized controlled clinical trials. More timely and effective evidence is needed to enhance the consistency and quality of and clinical outcomes achieved with SRS. The authors summarize the creation and implementation of a national SRS registry. The American Association of Neurological Surgeons (AANS) through NeuroPoint Alliance, Inc., started a successful registry effort with its lumbar spine initiative. Following a similar approach, the AANS and NeuroPoint Alliance collaborated with corporate partners and the American Society for Radiation Oncology to devise a data dictionary for an SRS registry. Through administrative and financial support from professional societies and corporate partners, a framework for implementation of the registry was created. Initial plans were devised for a 3-year effort encompassing 30 high-volume SRS centers across the country. Device-specific web-based data-extraction platforms were built by the corporate partners. Data uploaders were then used to port the data to a common repository managed by Quintiles, a national and international health care trials company. Audits of the data for completeness and veracity will be undertaken by Quintiles to ensure data fidelity. Data governance and analysis are overseen by an SRS board comprising equal numbers of representatives from the AANS and NeuroPoint Alliance. Over time, quality outcome assessments and post hoc research can be performed to advance the field of SRS. Stereotactic radiosurgery offers a high-technology approach to treating complex intracranial disorders. Improvements in the consistency and quality of care delivered to patients who undergo SRS should be afforded by the national registry effort that is underway. PMID

  15. Addressing Health Disparities through Multi-institutional, Multidisciplinary Collaboratories

    PubMed Central

    Fleming, Erik S.; Perkins, James; Easa, David; Conde, José G.; Baker, Richard S.; Southerland, William M.; Dottin, Robert; Benabe, Julio E.; Ofili, Elizabeth O.; Bond, Vincent C.; McClure, Shelia A.; Sayre, Michael H.; Beanan, Maureen J.; Norris, Keith C.

    2009-01-01

    The national research leadership has recently become aware of the tremendous potential of translational research as an approach to address health disparities. The Research Centers in Minority Institutions (RCMI) Translational Research Network (RTRN) is a research network that supports multi-institutional, multidisciplinary collaboration with a focus on key diseases and conditions for which disproportionately adverse racial and ethnic health disparities exist. The RTRN is designed to facilitate the movement of scientific advances across the translational research spectrum by providing researchers at different institutions with the infrastructure and tools necessary to collaborate on interdisciplinary and transdisciplinary research projects relating to specific health outcomes for which major racial/ethnic disparities exist. In the past, the difficulty of overcoming the restrictions imposed by time and space have made it difficult to carry out this type of large-scale, multilevel collaboration efficiently. To address this formidable challenge, the RTRN will deploy a translational research cluster system that uses “cyber workspaces” to bring researchers with similar interests together by using online collaboratory technology. These virtual meeting environments will provide a number of tools, including videoconferences (seminars, works in progress, meetings); project management tools (WebCT, Microsoft Share Point); and posting areas for projects, concepts, and other research and educational activities. This technology will help enhance access to resources across institutions with a common mission, minimize many of the logistical hurdles that impede intellectual exchange, streamline the planning and implementation of innovative interdisciplinary research, and assess the use of protocols and practices to assist researchers in interacting across and within cyber workspaces. PMID:18646341

  16. Integrated Multidisciplinary Fault Observation in Marmara Through MARSite

    NASA Astrophysics Data System (ADS)

    Meral Ozel, N.; Necmioglu, O.; Ozel, A. O.; Ergintav, S.; Tan, O.; Geli, L. B.; Favali, P.; Guralp, C. M.; Douglas, J.; Mathieu, P. P.; Gurbuz, C.; Erdik, M. O.

    2014-12-01

    MARSite Project, initiated in November 2012 under the EC/FP-7 framework, aims to coordinate research groups ranging from seismology to gas geochemistry in a comprehensive monitoring activity developed both in the Marmara Region based on collection of multidisciplinary data to be shared, interpreted and merged in consistent theoretical and practical models suitable for the implementation of good practices to move the necessary information to the end users in charge of seismic risk management of the region. In addition, processes involved in earthquake generation and the physics of short-term seismic transients, 4D deformations to understand earthquake cycle processes, fluid activity monitoring and seismicity under the sea floor using existing autonomous instrumentation, early warning and development of real-time shake and loss information, real- and quasi-real-time earthquake and tsunami hazard monitoring and earthquake-induced landslide hazard topics are also covered within MARSite. This presentation would provide a report on the progress achieved during the half-life of the project. In this respect, the main data server for the integration of real time network data has been finalized. Daily evaluation of online spring water and soil radon gas data in relation to seismic activity is in place, together with the continuous GPS data processing. A significant combination of postseismic (viscoelastic) deformation and afterslip was detected in the western segment of the 1999 Izmit rupture plane based on InSAR modeling. The optimum borehole depths have been identified based on seismic reflection studies and GURALP Systems is continuing its work on the manufacturing the borehole system. Seismic risk study for IGDAS Natural Gas Network including pipelines and its components has been carried out with several earthquake scenarios in Marmara Sea and an automatic shut-off algorithm has been developed for the automatic shut-off of the gas flow at the IGDAS district regulators

  17. The LUSI LAB project: a platform for multidisciplinary experimental studies

    NASA Astrophysics Data System (ADS)

    Mazzini, Adriano; Svensen, Henrik; Hensen, Christian; Scholz, Florian; Romeo, Giovanni; Hadi, Soffian; Husein, Alwi; Planke, Sverre; Akhmanov, Grigorii; Krueger, Martin

    2014-05-01

    Lusi is a spectacular mud eruption that started in northeast Java the 29 of May 2006 following a 6.3 M earthquake. Nearly eight years later Lusi is still active. The Lusi Lab is an ERC-funded project to perform multidisciplinary studies using Lusi as a natural laboratory. This represents an unprecedented opportunity to study an ongoing active high-temperature mud eruption and to evaluate the role of seismicity, local faulting and the neighbouring Arjuno-Welirang volcanic complex on the long-lasting mud eruption. A multipurpose hexacopter has been designed and constructed to access and monitor the otherwise inaccessible Lusi crater and its mud-filled outskirts. The "Lusi drone" showed to be a powerful monitoring and sampling tool duringteh fieldwork in Dec. 2013. Videos and photogrammetry were acquired with various cameras. Designed tools allow the drone to measure and log temperature and to complete remote-controlled sampling of mud, water and gas from the erupting crater. A collection of evenly spaced mud samples has been taken along a transect that extends for 1100 m outside the crater. The incubation of these will be used for geomicrobiological studies and will help to shed light on the type of the ongoing hydrocarbon generation and degradation. A network of temperature loggers deployed around the crater aims to investigate a correlation between seismic activity and temperature variation of the erupted mud. Geochemical analyses indicate that the geochemistry of the crater water represents a geochemical anomaly when comparing with both basinal brines and volcano-hosted hot springs. A combination of high temperatures in the source region and fluid-rock interactions with silicates and carbonate-rich lithologies can explain the geochemistry. This is consistent with the result of gas analyses and with a deep-seated (>4 km) source region, possibly related to the presence of hot igneous intrusions from the volcanic arc.

  18. Multi-disciplinary competence assessment: a case study in consensus and culture.

    PubMed

    Landry, L Y

    1999-09-01

    The case of May Redwing, an American Indian woman assessed for competence is examined in detail. The case highlights the interconnections between the cultures of medicine and law and notes the importance of criteria of competence assessment, but also underscores the necessity of attention to the patient's cultural background in a multi-disciplinary competence assessment team process. Three interrelated areas of inquiry are explored: (1) Can we expect a morally and politically justifiable assessment of competence from a multi-disciplinary approach? (2) What pitfalls threaten a multi-disciplinary approach? and (3) How are the patient's cultural background and values relevant to a proper assessment of competence? These questions are investigated in the context of analyzing and evaluating a particularly difficult case. Although focused on a specific case, the study is instructive and cautionary for any group undertaking the challenges of multi-disciplinary competence assessment. PMID:10616320

  19. [Multidisciplinary outpatient clinics for back pain patients--a new treatment program].

    PubMed

    Skouen, Jan Sture; Laerum, Even; Jensen, Thor Øivind

    2003-10-23

    Chronic low back pain (LBP) represents a major health problem, especially in Western Europe and North America. The aim of this study is to give an account of why a multidisciplinary treatment program in an outpatient spine clinic is the best treatment for many sub-acute and chronic LBP patients on long-term sick leave. We present an overview of documented treatment effects from multidisciplinary treatment programmes, an outline of the treatment in an outpatient spine clinic, and an account of why multidisciplinary programs are beneficial. The treatment of this patient group is also shown to be cost-effective when one differentiates between light and extensive multidisciplinary programmes. A future challenge rests in the fact that even after optimal treatment, approximately 20 % of patients still do not return to work. PMID:14600719

  20. Multi-disciplinary coupling effects for integrated design of propulsion systems

    NASA Technical Reports Server (NTRS)

    Chamis, C. C.; Singhal, S. N.

    1993-01-01

    Effective computational simulation procedures are described for modeling the inherent multi-disciplinary interactions which govern the accurate response of propulsion systems. Results are presented for propulsion system responses including multi-disciplinary coupling effects using coupled multi-discipline thermal, structural, and acoustic tailoring; an integrated system of multi-disciplinary simulators; coupled material behavior/fabrication process tailoring; sensitivities using a probabilistic simulator; and coupled materials, structures, fracture, and probabilistic behavior simulator. The results demonstrate that superior designs can be achieved if the analysis/tailoring methods account for the multi-disciplinary coupling effects. The coupling across disciplines can be used to develop an integrated coupled multi-discipline numerical propulsion system simulator.

  1. Response Surface Model Building and Multidisciplinary Optimization Using D-Optimal Designs

    NASA Technical Reports Server (NTRS)

    Unal, Resit; Lepsch, Roger A.; McMillin, Mark L.

    1998-01-01

    This paper discusses response surface methods for approximation model building and multidisciplinary design optimization. The response surface methods discussed are central composite designs, Bayesian methods and D-optimal designs. An over-determined D-optimal design is applied to a configuration design and optimization study of a wing-body, launch vehicle. Results suggest that over determined D-optimal designs may provide an efficient approach for approximation model building and for multidisciplinary design optimization.

  2. Clinical audit of multidisciplinary care at a medium-sized hospital in Spain

    PubMed Central

    2014-01-01

    Background Multidisciplinary care is a key enabler in the provision of high quality care for cancer patients. Despite compelling evidence supporting their benefit to patients and for providers, multidisciplinary cancer conferences (MCC) are not universally occurring. Team composition of MCC reflects the multidisciplinary nature of the body. Lack of nursing input can have a negative impact on team decision making. The objective of this study was to evaluate multidisciplinary care and adherence to national recommendations at a medium-sized hospital through a clinical audit of cancer conferences and clinical records. Methods A total of 77 multidisciplinary cancer conferences were visited and 496 electronic health records were reviewed. The regularity of meetings and multidisciplinary attendance were evaluated. Each electronic health record was checked to verify documented prospective discussion before any treatment was started. Results Nine multidisciplinary teams meet on a weekly or biweekly basis at the hospital with an average number of ten people and six different specialties represented. Average duration of meetings was 46.8 min. Though most patients (64.5%) were discussed at some point at the relevant cancer conference, only 40% had a documented multidisciplinary team discussion prior to the first treatment. Pathological stage (pTNM) was documented in 53.6% of clinical records. Conclusions Nursing representatives should be included as usual attendees at cancer conferences. Prospective discussion of all cancer cases should be encouraged. Use of checklists and systematic collection of key information, specifically cancer staging, could improve clinical documentation in the electronic clinical record. PMID:24597686

  3. [Multidisciplinary assessment for multimodal pain therapy. Indications and range of performance].

    PubMed

    Casser, H-R; Arnold, B; Brinkschmidt, T; Gralow, I; Irnich, D; Klimczyk, K; Nagel, B; Pfingsten, M; Sabatowski R; Schiltenwolf, M; Sittl, R; Söllner, W

    2013-08-01

    According to evidence-based German national guidelines for non-specific low back pain, a broad multidisciplinary assessment is indicated after persisting pain experience of 6 weeks in order to check the indications for an multi- and interdisciplinary pain therapy program. In this paper the necessary topics, the content and the disciplines involved as well as the extent of the multidisciplinary assessment are described as developed by the ad hoc commission on multimodal pain therapy of the German Pain Society. PMID:23903762

  4. Multidisciplinary approach to treatment of radiation-induced chest wall sarcoma.

    PubMed

    Kara, H Volkan; Gandolfi, Brad M; Williams, Judson B; D'Amico, Thomas A; Zenn, Michael R

    2016-08-01

    Radiation-induced sarcoma (RIS) is a rare complication following therapeutic external irradiation for lung cancer patients. Patients with RIS may develop recurrence or metastasis of the previous disease and also at high risk for early chest wall complications following operation, which requires close follow-up and multidisciplinary approach. We present a challenging case of RIS with a multidisciplinary teamwork in the decision-making and successful management. PMID:25663293

  5. In Absentia: An Exploratory Study of How Patients Are Considered in Multidisciplinary Cancer Team Meetings

    PubMed Central

    Hahlweg, Pola; Hoffmann, Jana; Härter, Martin; Frosch, Dominick L; Elwyn, Glyn; Scholl, Isabelle

    2015-01-01

    Background Multidisciplinary team meetings and shared decision-making are potential means of delivering patient-centred care. Not much is known about how those two paradigms fit together in cancer care. This study aimed to investigate how decisions are made in multidisciplinary team meetings and whether patient perspectives are incorporated in these decisions. Materials and Methods A qualitative study was conducted using non-participant observation at multidisciplinary team meetings (also called tumor boards) at the University Cancer Center Hamburg-Eppendorf, Germany. Two researchers recorded structured field notes from a total of N = 15 multidisciplinary team meetings. Data were analyzed using content analysis and descriptive statistics. Results Physicians mainly exchanged medical information and based their decision-making on this information. Individual patient characteristics or their treatment preferences were rarely considered or discussed. In the few cases where patient preferences were raised as a topic, this information did not seem to be taken into account in decision-making processes about treatment recommendations. Conclusion The processes in multidisciplinary team meetings we observed did not exhibit shared decision-making. Patient perspectives were absent. If multidisciplinary team meetings wish to become more patient-centred they will have to modify their processes and find a way to include patient preferences into the decision-making process. PMID:26441328

  6. Biophotonics: a European perspective

    NASA Astrophysics Data System (ADS)

    Robin, Thierry; Cochard, Jacques; Breussin, Frédéric

    2013-03-01

    The objective of the present work is to determine the opportunities and challenges for Biophotonics business development in Europe for the next five years with a focus on sensors and systems: for health diagnostics and monitoring; for air, water and food safety and quality control. The development of this roadmap was initiated and supported by EPIC (The European Photonics Industry Consortium). We summarize the final roadmap data: market application segments and trends, analysis of the market access criteria, analysis of the technology trends and major bottlenecks and challenges per application.

  7. Eastern European risk management

    SciTech Connect

    Honey, J.A. )

    1992-01-01

    Here the authors assess Eastern European risk management practices through the evaluation of the nuclear power plants in the region. This evaluation is limited to the Soviet-designed and -built VVER-440 pressurized water reactors (PWRs) that are currently operating in Bulgaria, Czechoslovakia, Hungary, Russia, and the Ukraine and until recently operated at Greifswald in the former East Germany. This evaluation is based on the basic design of the plants, a safety evaluation of the Greifswald facility by representatives from the Federal Republic of Germany and personal visits by the author to Greifswald and Loviisa.

  8. GENIUS: A tool for multi-disciplinary and multi-scalar databases

    NASA Astrophysics Data System (ADS)

    Bonhomme, M.; Masson, V.; Adolphe, L.; Faraut, S.

    2013-12-01

    Cities are responsible for the majority of energy consumption on the planet. As a consequence, researches regarding energy use in urban context have been increasing for the last decades. Recently the interrelationship between city, energy consumption and urban microclimate appeared as a key component of urban sustainability. To be accurate, those studies must take into account a multidisciplinary urban context and modelling tools need high definition data. Nevertheless, at the city scale, input data is either imprecise or only available for small areas. In particular, there is a lack of information about buildings footprints, roofs sloping, envelope materials, etc. Moreover, the existing data do not allow researchers to explore prospective issues such as climate change or future urban development. In this sense, we developed a new tool called GENIUS (GENerator of Interactive Urban blockS) to build high definition and evolutionary maps from available databases. GENIUS creates maps composed of archetypical neighbourhood coming as shape-files of polygons with additional information (height, age, use, thermal insulation, etc.). Those archetypical neighbourhoods come to seven types of urban blocks that can be found in most European cities. Those types can be compared with Stewart and Oke Local Climate Zones (LCZ). The first step of our method is to transform an existing map into an 'archetypical map'. To do this, the urban database of the IGN (French Geographical Institute) was used. The maps were divided into cells of 250 meters resolution. For each cell, about 40 morphological indicators were calculated. Seven groups of blocks were then identified by means of Principal Component Analysis. GENIUS databases are also able to evolve through time. As a matter of fact, the initial map is transformed, year after year, by taking into account changes in density and urban history. In that sense, GENIUS communicates with NEDUM, a model developed by the CIRED (International

  9. Medical research and multidisciplinary applications with laser-accelerated beams: the ELIMED netwotk at ELI-Beamlines

    NASA Astrophysics Data System (ADS)

    Tramontana, A.; Anzalone, A.; Candiano, G.; Carpinelli, M.; Cirrone, G. A. P.; Cuttone, G.; Korn, G.; Licciardello, T.; Maggiore, M.; Manti, L.; Margarone, D.; Musumarra, A.; Perozziello, F.; Pisciotta, P.; Raffaele, L.; Romano, F.; Romano, F. P.; Stancampiano, C.; Schillaci, F.; Scuderi, V.; Torrisi, L.; Tudisco, S.

    2014-04-01

    Laser accelerated proton beams represent nowadays an attractive alternative to the conventional ones and they have been proposed in different research fields. In particular, the interest has been focused in the possibility of replacing conventional accelerating machines with laser-based accelerators in order to develop a new concept of hadrontherapy facilities, which could result more compact and less expensive. With this background the ELIMED (ELIMED: ELI-Beamlines MEDical applications) research project has been launched by LNS-INFN researchers (Laboratori Nazionali del Sud-Istituto Nazionale di Fisica Nucleare, Catania, IT) and ASCR-FZU researchers (Academy of Sciences of the Czech Republic-Fyzikální ústar, Prague, Cz), within the pan-European ELI-Beamlines facility framework. Its main purposes are the demonstration of future applications in hadrontherapy of optically accelerated protons and the realization of a laser-accelerated ion transport beamline for multidisciplinary applications. Several challenges, starting from laser-target interaction and beam transport development, up to dosimetric and radiobiological issues, need to be overcome in order to reach the final goals. The design and the realization of a preliminary beam handling and dosimetric system and of an advanced spectrometer for high energy (multi-MeV) laser-accelerated ion beams will be shortly presented in this work.

  10. Late Quaternary cave bears and brown bears in Europe: implications for distribution, chronology, and extinction based on a multidisciplinary approach

    NASA Astrophysics Data System (ADS)

    Pacher, Martina

    2010-05-01

    Cave bear remains are one of the most numerous fossils found in European caves. Despite their frequency of occurrence, many aspects of cave bear palaeontology still remain poorly understood. New methodological approaches and ongoing studies led to controversial results and discussion about its taxonomy, palaeoecology, and final extinction. Are we dealing with one single or several species of cave bears? Was cave bear exclusively vegetarian or after all more omnivorous? Did he go extinct before or after the Late Glacial Maximum? Was cave bear restricted to Europe or did he also occur in Asia? Late Pleistocene brown bears, on the other hand, are often rare and little is known about the possible co-occurrence of cave and brown bears during the Late Pleistocene. Based on direct radiocarbon dates the distribution pattern of both, cave and brown bears is reconstructed during the Late Pleistocene in Europe. In addition, the reasons for the achieved pattern will be tested leading to the main question - why did cave bear become extinct while brown bears survived until today? To answer this question palaeobiological data of Late Pleistocene cave and brown bears will be tested against results from isotope analyses, while aDNA data may contribute to the question of distinct local population or even species of bears. The current state of evidence will be presented and on the basis of resulting pattern implications for further multi-disciplinary studies will be discussed.

  11. [Multidisciplinary guidelines for the management of community-acquired pneumonia].

    PubMed

    Torres, Antoni; Barberán, José; Falguera, Miquel; Menéndez, Rosario; Molina, Jesús; Olaechea, Pedro; Rodríguez, Alejandro

    2013-03-01

    Community-acquired pneumonia (CAP) is an infectious respiratory disease with an incidence that ranges from 3 to 8 cases per 1,000 inhabitants per year. This incidence increases with age and comorbidities. Forty per cent of CAP patients require hospitalization and around 10% of these patients are admitted in an Intensive Care Unit (ICU). Several studies have suggested that the implementation of clinical guidelines has a positive impact in the outcome of patients including mortality and length of stay. The more recent and used guidelines are those from Infectious Diseases Society of America/American Thoracic Society, published in 2007, the 2009 from the British Thoracic Society, and that from the European Respiratory Society/European Society of Clinical Microbiology and Infectious Diseases, published in 2010. In Spain, the most recently released guideline is the Sociedad Española de Neumología y Cirugía Torácica-2011 guideline. The present guidelines GNAC are designed to be used by the majority of health-care professionals that can participate in the care of CAP patients including diagnosis, decision of hospital and ICU admission, treatment and prevention. The Centro Cochrane Iberoamericano (CCIB) has participated in summarizing the previous guidelines and in the bibliography search. For each one of the following sections the panel of experts has developed a table with recommendations classified according to its evidence, strength and practical applicability using the Grading of Recommendations of Assessment Development and Evaluations (GRADE) system: 1. Epidemiology, microbiological etiology and antibiotic resistances.2. Clinical and microbiological diagnosis.3. Prognostic scales and decision of hospital admission.4. ICU admission criteria. 5. Empirical and definitive antibiotic treatment.6. Treatment failure. 7. Prevention. PMID:23276610

  12. ELIMED, MEDical and multidisciplinary applications at ELI-Beamlines

    NASA Astrophysics Data System (ADS)

    Schillaci, F.; Anzalone, A.; Cirrone, G. A. P.; Carpinelli, M.; Cuttone, G.; Cutroneo, M.; De Martinis, C.; Giove, D.; Korn, G.; Maggiore, M.; Manti, L.; Margarone, D.; Musumarra, A.; Perozziello, F. M.; Petrovic, I.; Pisciotta, P.; Renis, M.; Ristic-Fira, A.; Romano, F.; Romano, F. P.; Schettino, G.; Scuderi, V.; Torrisi, L.; Tramontana, A.; Tudisco, S.

    2014-04-01

    ELI-Beamlines is one of the pillars of the pan-European project ELI (Extreme Light Infrastructure). It will be an ultra high-intensity, high repetition-rate, femtosecond laser facility whose main goal is generation and applications of high-brightness X-ray sources and accelerated charged particles in different fields. Particular care will be devoted to the potential applicability of laser-driven ion beams for medical treatments of tumors. Indeed, such kind of beams show very interesting peculiarities and, moreover, laser-driven based accelerators can really represent a competitive alternative to conventional machines since they are expected to be more compact in size and less expensive. The ELIMED project was launched thanks to a collaboration established between FZU-ASCR (ELI-Beamlines) and INFN-LNS researchers. Several European institutes have already shown a great interest in the project aiming to explore the possibility to use laser-driven ion (mostly proton) beams for several applications with a particular regard for medical ones. To reach the project goal several tasks need to be fulfilled, starting from the optimization of laser-target interaction to dosimetric studies at the irradiation point at the end of a proper designed transport beam-line. Researchers from LNS have already developed and successfully tested a high-dispersive power Thomson Parabola Spectrometer, which is the first prototype of a more performing device to be used within the ELIMED project. Also a Magnetic Selection System able to produce a small pencil beam out of a wide energy distribution of ions produced in laser-target interaction has been realized and some preliminary work for its testing and characterization is in progress. In this contribution the status of the project will be reported together with a short description of the of the features of device recently developed.

  13. Multidisciplinary Design Optimization of A Highly Flexible Aeroservoelastic Wing

    NASA Astrophysics Data System (ADS)

    Haghighat, Sohrab

    A multidisciplinary design optimization framework is developed that integrates control system design with aerostructural design for a highly-deformable wing. The objective of this framework is to surpass the existing aircraft endurance limits through the use of an active load alleviation system designed concurrently with the rest of the aircraft. The novelty of this work is two fold. First, a unified dynamics framework is developed to represent the full six-degree-of-freedom rigid-body along with the structural dynamics. It allows for an integrated control design to account for both manoeuvrability (flying quality) and aeroelasticity criteria simultaneously. Secondly, by synthesizing the aircraft control system along with the structural sizing and aerodynamic shape design, the final design has the potential to exploit synergies among the three disciplines and yield higher performing aircraft. A co-rotational structural framework featuring Euler--Bernoulli beam elements is developed to capture the wing's nonlinear deformations under the effect of aerodynamic and inertial loadings. In this work, a three-dimensional aerodynamic panel code, capable of calculating both steady and unsteady loadings is used. Two different control methods, a model predictive controller (MPC) and a 2-DOF mixed-norm robust controller, are considered in this work to control a highly flexible aircraft. Both control techniques offer unique advantages that make them promising for controlling a highly flexible aircraft. The control system works towards executing time-dependent manoeuvres along with performing gust/manoeuvre load alleviation. The developed framework is investigated for demonstration in two design cases: one in which the control system simply worked towards achieving or maintaining a target altitude, and another where the control system is also performing load alleviation. The use of the active load alleviation system results in a significant improvement in the aircraft performance

  14. Improved integration and discoverability of tephra data for multidisciplinary applications

    NASA Astrophysics Data System (ADS)

    Kuehn, S. C.; Bursik, M. I.; Pouget, S.

    2013-12-01

    Tephra deposits form a common thread which connects diverse, multidisciplinary research directions that share overlapping data needs. Tephra beds reflect the magmatic, eruptive, and dispersal processes involved in their generation as well as the tectonic environment from which they originate. Therefore, they are globally important for examining links between tectonics, magma chemistry, volcano behavior, and environmental effects. They are fundamental for understanding past eruptions and future hazards, and they are key for dating both geologic and prehistoric events. It is, perhaps, in tephrochronology that tephra beds find their most diverse applications: providing isochrons of nearly unmatched temporal precision across regional to continental and even inter-continental distances; tying together glacial, marine, lacustrine, and terrestrial records; and helping to answer major questions in climate change, archaeology, paleontology, paleoecology, paleolimnology, paleoseismology, and geomorphology, among others. Tephra data include physical (particle size, bed thickness), mineralogical, geographic, time-stratigraphic, geochemical, and interpretive information. Data collected over decades currently exist largely in disparate, disconnected, and commonly offline datasets, and this severely limits discovery and accessibility. The integration of such data along with eruption catalogs into unified or interoperable databases linked at the eruption scale is a critical need. The need is especially acute for tephrochronology, which is by its very nature a comparative technique requiring access to ideally comprehensive, multiparameter datasets for the identification and correlation of tephra beds. To meet the needs of this large research community, we envision (1) the integration of decades of tephra data and available metadata into a system with a single point of access for all data types, (2) development of an interface and mechanism for multiparameter searching, (3

  15. A multidisciplinary optimization methodology for rocket vehicle systems

    NASA Astrophysics Data System (ADS)

    Colonno, Michael Richard

    Rocket vehicles have traditionally been designed in an iterative fashion, beginning with system requirements before proceeding sequentially through requisite analytical disciplines until resources are exhausted. A sequentially designed system, while adequate, is not an optimum due to the approximations and loss of fidelity inherent in separating analytical disciplines which are, in fact, coupled. Recently, increased computational power and advances in algorithms have allowed multidisciplinary optimization (MDO) to emerge as a system-level design tool accessible to industry. To date, MDO has primarily been applied to some facets of aircraft systems and, to a lesser extent, rocket vehicles in literature but has not yet met with widespread industry use. To this end, four obstacles have been identified: (1) MDO efforts to date have focused on system-level parameters rather than physical dimensions and hence have not yielded a preliminary design which includes manufacturing, cost, and other constraints, (2) Prohibitive computational performance requirements associated with high-fidelity analyses such as computational fluid mechanics (CFD) and finite element analysis (FEA), (3) Lack of an integrated design environment which incorporates computational tools already widely used in industry while remaining accessible to individual users without high-level expertise in the individual tools, and (4) The widely-varying and tightly-coupled environments to which rocket vehicles are typically exposed, including analyses not required for aircraft applications. Here, an MDO method for rocket systems has been formulated which simultaneously overcomes the challenges listed above. First, a response surface-based approach to modeling computationally expensive analyses with arbitrary dimensionality and general constraints was developed. This method focused on an evenly-distributed representation of the entire feasible region at any fidelity level, including combinations of discrete and

  16. Multidisciplinary design optimization of low-noise transport aircraft

    NASA Astrophysics Data System (ADS)

    Leifsson, Leifur Thor

    The objective of this research is to examine how to design low-noise transport aircraft using Multidisciplinary Design Optimization (MDO). The subject is approached by designing for low-noise both implicitly and explicitly. The explicit design approach involves optimizing an aircraft while explicitly constraining the noise level. An MDO framework capable of optimizing both a cantilever wing and a Strut-Braced-Wing (SBW) aircraft was developed. The objective is to design aircraft for low-airframe-noise at the approach conditions and quantify the change in weight and performance with respect to a traditionally designed aircraft. The results show that reducing airframe noise by reducing approach speed alone, will not provide significant noise reduction without a large performance and weight penalty. Therefore, more dramatic changes to the aircraft design are needed to achieve a significant airframe noise reduction. Another study showed that the trailing-edge flap can be eliminated, as well as all the noise associated with that device, without incurring a significant weight and performance penalty. Lastly, an airframe noise analysis showed that a SBW aircraft with short fuselage-mounted landing gear could have a similar or potentially a lower airframe noise level than a comparable cantilever wing aircraft. The implicit design approach involves selecting a configuration that supports a low-noise operation, and optimizing for performance. In this study a Blended-Wing-Body (BWB) transport aircraft, with a conventional and a distributed propulsion system, was optimized for minimum take-off gross weight. The effects of distributed propulsion were studied using an MDO framework previously developed at Virginia Tech. The results show that more than two thirds of the theoretical savings of distributed propulsion are required for the BWB designs with a distributed propulsion system to have comparable gross weight as those with a conventional propulsion system. Therefore

  17. Outcomes of Multidisciplinary Management in Pediatric Low-Grade Gliomas

    SciTech Connect

    Oh, Kevin S.; Hung, Jonathan; Robertson, Patricia L.; Garton, Hugh J.; Muraszko, Karin M.; Sandler, Howard M.; Hamstra, Daniel A.

    2011-11-15

    Purpose: To evaluate the outcomes in pediatric low-grade gliomas managed in a multidisciplinary setting. Methods and Materials: We conducted a single-institution retrospective study of 181 children with Grade I-II gliomas. Log-rank and stepwise Cox proportional hazards models were used to analyze freedom from progression (FFP) and overall survival (OS). Results: Median follow-up was 6.4 years. Thirty-four (19%) of patients had neurofibromatosis Type 1 (NF1) and because of their favorable prognosis were evaluated separately. In the 147 (81%) of patients without NF1, actuarial 7-year FFP and OS were 67 {+-} 4% (standard error) and 94 {+-} 2%, respectively. In this population, tumor location in the optic pathway/hypothalamus was associated with worse FFP (39% vs. 76%, p < 0.0003), but there was no difference in OS. Age {<=}5 years was associated with worse FFP (52% vs. 75%, p < 0.02) but improved OS (97% vs. 92%, p < 0.05). In those with tissue diagnosis, gross total resection (GTR) was associated with improved 7-year FFP (81% vs. 56%, p < 0.02) and OS (100% vs. 90%, p < 0.03). In a multivariate model, only location in the optic pathway/hypothalamus predicted worse FFP (p < 0.01). Fifty patients received radiation therapy (RT). For those with less than GTR, adjuvant RT improved FFP (89% vs. 49%, p < 0.003) but not OS. There was no difference in OS between patient groups given RT as adjuvant vs. salvage therapy. In NF1 patients, 94% of tumors were located in the optic pathway/hypothalamus. With a conservative treatment strategy in this population, actuarial 7-year FFP and OS were 73 {+-} 9% and 100%, respectively. Conclusions: Low-grade gliomas in children {<=}5 years old with tumors in the optic pathway/hypothalamus are more likely to progress, but this does not confer worse OS because of the success of salvage therapy. When GTR is not achieved, adjuvant RT improves FFP but not OS. Routine adjuvant RT can be avoided and instead reserved as salvage.

  18. A multidisciplinary system for monitoring and forecasting Etna volcanic plumes

    NASA Astrophysics Data System (ADS)

    Coltelli, Mauro; Prestifilippo, Michele; Spata, Gaetano; Scollo, Simona; Andronico, Daniele

    2010-05-01

    columns high up to several kilometers above sea level and, on the basis of parameters such as mass eruption rate and total grain-size distributions, showed different explosive style. The monitoring and forecasting system is going on developing through the installation of new instruments able to detect different features of the volcanic plumes (e.g. the dispersal and sedimentation processes) in order to reduce the uncertainty of the input parameters used in the modeling. This is crucial to perform a reliable forecasting. We show that multidisciplinary approaches can really give useful information on the presence of volcanic ash and consequently to prevent damages and airport disruptions.

  19. Improving spacecraft design using a multidisciplinary design optimization methodology

    NASA Astrophysics Data System (ADS)

    Mosher, Todd Jon

    2000-10-01

    Spacecraft design has gone from maximizing performance under technology constraints to minimizing cost under performance constraints. This is characteristic of the "faster, better, cheaper" movement that has emerged within NASA. Currently spacecraft are "optimized" manually through a tool-assisted evaluation of a limited set of design alternatives. With this approach there is no guarantee that a systems-level focus will be taken and "feasibility" rather than "optimality" is commonly all that is achieved. To improve spacecraft design in the "faster, better, cheaper" era, a new approach using multidisciplinary design optimization (MDO) is proposed. Using MDO methods brings structure to conceptual spacecraft design by casting a spacecraft design problem into an optimization framework. Then, through the construction of a model that captures design and cost, this approach facilitates a quicker and more straightforward option synthesis. The final step is to automatically search the design space. As computer processor speed continues to increase, enumeration of all combinations, while not elegant, is one method that is straightforward to perform. As an alternative to enumeration, genetic algorithms are used and find solutions by reviewing fewer possible solutions with some limitations. Both methods increase the likelihood of finding an optimal design, or at least the most promising area of the design space. This spacecraft design methodology using MDO is demonstrated on three examples. A retrospective test for validation is performed using the Near Earth Asteroid Rendezvous (NEAR) spacecraft design. For the second example, the premise that aerobraking was needed to minimize mission cost and was mission enabling for the Mars Global Surveyor (MGS) mission is challenged. While one might expect no feasible design space for an MGS without aerobraking mission, a counterintuitive result is discovered. Several design options that don't use aerobraking are feasible and cost

  20. Integrated multidisciplinary fault observation in Marmara Through MARSite - Project Progress

    NASA Astrophysics Data System (ADS)

    Meral Ozel, Nurcan; Necmioglu, Ocal; Oguz Ozel, Asım; Ergintav, Semih; Geli, Louis Louis; Favali, Paolo; Guralp, Cansun; Douglas, John; Mathieu, Pierre-Philippe; Tan, Onur; Gürbüz, Cemil; Erdik, Mustafa

    2015-04-01

    This presentation provides a progress overview of the EC/FP-7 MARSite Project started in November 2012, which aims to coordinate research groups ranging from seismology to gas geochemistry in a comprehensive monitoring activity developed both in the Marmara Region based on collection of multidisciplinary data to be shared, interpreted and merged in consistent theoretical and practical models suitable for the implementation of good practices to move the necessary information to the end users in charge of seismic risk management of the region. In addition, processes involved in earthquake generation and the physics of short-term seismic transients, 4D deformations to understand earthquake cycle processes, fluid activity monitoring and seismicity under the sea floor using existing autonomous instrumentation, early warning and development of real-time shake and loss information, real- and quasi-real-time earthquake and tsunami hazard monitoring and earthquake-induced landslide hazard topics are also covered within MARSite. This presentation would provide a report on the progress achieved during the half-life of the project. In this respect, the main data server for the integration of real time network data has been finalized. Daily evaluation of online spring water and soil radon gas data in relation to seismic activity is in place, together with the continuous GPS data processing. A significant combination of postseismic (viscoelastic) deformation and afterslip was detected in the western segment of the 1999 Izmit rupture plane based on InSAR modeling. The optimum borehole depths have been identified based on seismic reflection studies and GURALP Systems is continuing its work on the manufacturing the borehole system. Seismic risk study for IGDAS Natural Gas Network including pipelines and its components has been carried out with several earthquake scenarios in Marmara Sea and an automatic shut-off algorithm has been developed for the automatic shut-off of the gas

  1. EAC: The European Astronauts Centre

    NASA Astrophysics Data System (ADS)

    Ripoll, Andres

    The newly established European Astronauts Centre (EAC) in Cologne represents the European Astronauts Home Base and will become a centre of expertise on European astronauts activities. The paper gives an overview of the European approach to man-in-space, describes the European Astronauts Policy and presents the major EAC roles and responsibilities including the management of selection, recruitment and flight assignment of astronauts; the astronauts support and medical surveillance; the supervision of the astronauts' non-flight assignments; crew safety; the definition of the overall astronauts training programme; the scheduling and supervision of the training facilities; the implementation of Basic Training; the recruitment, training and certification of instructors, and the interface to NASA in the framework of the Space Station Freedom programme. An overview is given on the organisation of EAC, and on the European candidate astronauts selection performed in 1991.

  2. European Conference on Health Economics.

    PubMed

    Malmivaara, Antti

    2010-12-01

    The biennial European Conference on Health Economics was held in Finland this year, at the Finlandia Hall in the centre of Helsinki. The European conferences rotate among European countries and fall between the biennial world congresses organized by the International Health Economics Association (iHEA). A record attendance of approximately 800 delegates from 50 countries around the world were present at the Helsinki conference. The theme of the conference was 'Connecting Health and Economics'. All major topics of health economics were covered in the sessions. For the first time, social care economics was included in the agenda of the European Conference as a session of its own. PMID:21155696

  3. Multidisciplinary approach to evaluate flood damage for residential buildings: first results in Northern Italy

    NASA Astrophysics Data System (ADS)

    Luino, Fabio

    2015-04-01

    Flooding is the most common natural instability process in Italy. Flood damage are the results of land-use planning policies which, starting chiefly from the late 1950s and early 1960s, did not take into account the geomorphologic-hydraulic characteristics of an area or the its historical data on past flood events. Historically, compared to other areas, riverside property has always been less valuable. Unfortunately, year after year, even areas of high recreational and environmental value were intensely urbanized despite their being exposed to the threat of flooding. As the number of residential dwellings, infrastructure and industrial buildings increased, what was originally a hazard became a risk. For each flood event, the damage depends on the specific land-use of the area and subsequently on the elements at risk in the area involved and its vulnerability, expressed as a percentage of the element that has actually been lost during the event. This is why a comprehensive knowledge of the area it is so important for conducting a detailed survey of an area's structures and infrastructure and to evaluate the degree of vulnerability. This paper presents first results in Italy of the European Project called DAMAGE, the first attempt by the civil protection agencies of several European Union member states to devise a common methodology for the assessment of damage caused by natural or anthropic disasters. The main objective was to create an initial tool for practical and immediate application by civil protection agencies and local governments, to assess damage in a multidimensional perspective that takes into account infrastructure, the economy, the environment and social problems. Within the framework of a broad-based project for the evaluation and collection of reports on damage caused by floods, the CNR-IRPI of Turin and Regione Lombardia have directed attention to the town of Cittiglio (province of Varese), which was struck by severe flash flood in May 2002. One of

  4. A New Impetus for European Youth. European Commission White Paper.

    ERIC Educational Resources Information Center

    Commission of the European Communities, Brussels (Belgium).

    Despite their highly divergent situations, young people largely share the same values, ambitions, and difficulties. Despite the more complex social and economic context in which young Europeans are currently living, they are well equipped to adapt. National and European policymakers must facilitate this process of change by making young people…

  5. Issues and Strategies in Solving Multidisciplinary Optimization Problems

    NASA Technical Reports Server (NTRS)

    Patnaik, Surya

    2013-01-01

    Optimization research at NASA Glenn Research Center has addressed the design of structures, aircraft and airbreathing propulsion engines. The accumulated multidisciplinary design activity is collected under a testbed entitled COMETBOARDS. Several issues were encountered during the solution of the problems. Four issues and the strategies adapted for their resolution are discussed. This is followed by a discussion on analytical methods that is limited to structural design application. An optimization process can lead to an inefficient local solution. This deficiency was encountered during design of an engine component. The limitation was overcome through an augmentation of animation into optimization. Optimum solutions obtained were infeasible for aircraft and airbreathing propulsion engine problems. Alleviation of this deficiency required a cascading of multiple algorithms. Profile optimization of a beam produced an irregular shape. Engineering intuition restored the regular shape for the beam. The solution obtained for a cylindrical shell by a subproblem strategy converged to a design that can be difficult to manufacture. Resolution of this issue remains a challenge. The issues and resolutions are illustrated through a set of problems: Design of an engine component, Synthesis of a subsonic aircraft, Operation optimization of a supersonic engine, Design of a wave-rotor-topping device, Profile optimization of a cantilever beam, and Design of a cylindrical shell. This chapter provides a cursory account of the issues. Cited references provide detailed discussion on the topics. Design of a structure can also be generated by traditional method and the stochastic design concept. Merits and limitations of the three methods (traditional method, optimization method and stochastic concept) are illustrated. In the traditional method, the constraints are manipulated to obtain the design and weight is back calculated. In design optimization, the weight of a structure becomes the

  6. Multidisciplinary studies on ancient sandstone quarries of Western Sardinia (Italy).

    NASA Astrophysics Data System (ADS)

    Grillo, Silvana Maria; Del Vais, Carla; Naitza, Stefano

    2013-04-01

    The ancient coastal quarries of Mediterranean are increasingly considered geosites of multidisciplinary relevance. They are sites of historical-archaeological interest that show ancient techniques of stone extraction; they are significant for cultural heritage conservation and restoration, as sources of the stones used in ancient buildings and monuments; they are sites of geological relevance, as often retain important stratigraphic sections; they are also useful markers of secular changes in the sea level. A multisciplinary study is in progress on the ancient quarries of the Sinis region (western Sardinia island), integrating archaeological, geological, minero-petrographical data. In Sardinia, coastal quarries have been established from Punic and Roman times. Many of them exploited Quaternary sediments along the southern and western coasts of the island. They consist of middle-late Pleistocene marine conglomerates and carbonate sandstones, and of coastal (aeolian) carbonate sandstones. Sandstone blocks of different sizes have been widely used in ancient cities for buildings, defensive works, harbours, etc. Three main areas of stone extraction (San Giovanni di Sinis, Punta Maimoni, Is Arutas) have been so far recognized in the Sinis. GIS-supported mapping and documentation of the sites includes their geology and stratigraphy, the extension and layout of the quarries, and an evaluation of volumes of extracted rocks. Documented archaeological evidences include ancient extraction fronts, spoil heaps, working areas, working traces in the old fronts, transport routes of blocks, and traces of loading facilities. The study is aimed at reconstructing the relationships of the quarries with the urban areas of Sinis, as the ancient Punic-Roman city of Tharros. Consequently, a minero-petrographical characterization (optical microscopy, XRD) is performed on sandstones sampled in each quarry, and in historical buildings in Tharros and other centres of the region (Cabras

  7. The European initiative on low-dose risk research: from the HLEG to MELODI.

    PubMed

    Belli, Mauro; Tabocchini, Maria Antonella; Jourdain, Jean-René; Salomaa, Sisko; Repussard, Jacques

    2015-09-01

    The importance of low-dose risk research for radiation protection is now widely recognised. The European Commission (EC) and five European Union (EU) Member States involved in the Euratom Programme set up in 2008 a 'High Level and Expert Group on European Low Dose Risk Research' (HLEG) aimed at identifying research needs and proposing a better integration of European efforts in the field. The HLEG revised the research challenges and proposed a European research strategy based on a 'Multidisciplinary European LOw Dose Initiative' (MELODI). In April 2009, five national organisations, with the support of the EC, created the initial core of MELODI (http://www.melodi-online.eu) with a view to integrate the EU institutions with significant programmes in the field, while being open to other scientific organisations and stakeholders, and to develop an agreed strategic research agenda (SRA) and roadmap. Since then, open workshops have been organised yearly, exploring ideas for SRA implementation. As of October 2014, 31 institutions have been included as members of MELODI. HLEG recommendations and MELODI SRA have become important reference points in the radiation protection part of the Euratom Research Programme. MELODI has established close interactions through Memorandum of Understanding with other European platforms involved in radiation protection (Alliance, NERIS and EURADOS) and, together with EURADOS, with the relevant medical European Associations. The role of Joint Programming in priority setting, foreseen in the forthcoming EU Horizon 2020, calls for keeping MELODI an open, inclusive and transparent initiative, able to avoid redundancies and possible conflicts of interest, while promoting common initiatives in radiation protection research. An important issue is the establishment of a proper methodology for managing these initiatives, and this includes the set-up of an independent MELODI Scientific Committee recently extended to Alliance, NERIS and EURADOS, with

  8. The Importance of Multidisciplinary Management during Prenatal Care for Cleft Lip and Palate

    PubMed Central

    Han, Hyun Ho; Choi, Eun Jeong; Kim, Ji Min; Shin, Jong Chul

    2016-01-01

    Background The prenatal ultrasound detection of cleft lip with or without cleft palate (CL/P) and its continuous management in the prenatal, perinatal, and postnatal periods using a multidisciplinary team approach can be beneficial for parents and their infants. In this report, we share our experiences with the prenatal detection of CL/P and the multidisciplinary management of this malformation in our institution's Congenital Disease Center. Methods The multidisciplinary team of the Congenital Disease Center for mothers of children with CL/P is composed of obstetricians, plastic and reconstructive surgeons, pediatricians, and psychiatrists. A total of 11 fetuses were diagnosed with CL/P from March 2009 to December 2013, and their mothers were referred to the Congenital Disease Center of our hospital. When CL/P is suspected in the prenatal ultrasound screening examination, the pregnant woman is referred to our center for further evaluation. Results The abortion rate was 28% (3/11). The concordance rate of the sonographic and final diagnoses was 100%. Ten women (91%) reported that they were satisfied with the multidisciplinary management in our center. Conclusions Although a child with a birth defect is unlikely to be received well, the women whose fetuses were diagnosed with CL/P on prenatal ultrasound screening and who underwent multidisciplinary team management were more likely to decide to continue their pregnancy. PMID:27019808

  9. Framework for Multidisciplinary Analysis, Design, and Optimization with High-Fidelity Analysis Tools

    NASA Technical Reports Server (NTRS)

    Orr, Stanley A.; Narducci, Robert P.

    2009-01-01

    A plan is presented for the development of a high fidelity multidisciplinary optimization process for rotorcraft. The plan formulates individual disciplinary design problems, identifies practical high-fidelity tools and processes that can be incorporated in an automated optimization environment, and establishes statements of the multidisciplinary design problem including objectives, constraints, design variables, and cross-disciplinary dependencies. Five key disciplinary areas are selected in the development plan. These are rotor aerodynamics, rotor structures and dynamics, fuselage aerodynamics, fuselage structures, and propulsion / drive system. Flying qualities and noise are included as ancillary areas. Consistency across engineering disciplines is maintained with a central geometry engine that supports all multidisciplinary analysis. The multidisciplinary optimization process targets the preliminary design cycle where gross elements of the helicopter have been defined. These might include number of rotors and rotor configuration (tandem, coaxial, etc.). It is at this stage that sufficient configuration information is defined to perform high-fidelity analysis. At the same time there is enough design freedom to influence a design. The rotorcraft multidisciplinary optimization tool is built and substantiated throughout its development cycle in a staged approach by incorporating disciplines sequentially.

  10. European Schoolnet: Enabling School Networking

    ERIC Educational Resources Information Center

    Scimeca, Santi; Dumitru, Petru; Durando, Marc; Gilleran, Anne; Joyce, Alexa; Vuorikari, Riina

    2009-01-01

    School networking is increasingly important in a globalised world, where schools themselves can be actors on an international stage. This article builds on the activities and experience of the longest established European initiative in this area, European Schoolnet (EUN), a network of 31 Ministries of Education. First, we offer an introduction…

  11. What Audience for European Television?

    ERIC Educational Resources Information Center

    Wendelbo, Harald Arni

    This discussion of the audience for European television argues that satellite television has taken an upside-down approach, i.e., it has begun by focusing on the hardware, and then the software, before checking to see if there would be a user at the end of the line willing to pay for the whole operation. "European television" is then defined as…

  12. The European Dimension in Education.

    ERIC Educational Resources Information Center

    Council of Europe, Strasbourg (France). Directorate of Education, Culture and Sport, Documentation Section.

    This paper addresses concerns about a European dimension in education that has been created by the enlargement of the European Union (EU) (the inclusion of Austria, Finland, and Sweden) and the gradual transformations of institutions into a future federal state. Sections of the paper include: (1) "Introduction"; (2) "Defining the European…

  13. An American Construction of European Education Space

    ERIC Educational Resources Information Center

    Silova, Iveta; Brehm, William C.

    2010-01-01

    The construction of the European education space has typically been attributed to European education policy makers, institutions, and networks. Rarely do scholars consider the role of outside, non-European actors in shaping the terrain of European education thought and practice. This article considers the construction of the European education…

  14. European guidelines for the accreditation of Sleep Medicine Centres.

    PubMed

    Pevernagie, Dirk

    2006-06-01

    This document describes guidelines for accreditation of Sleep Medicine Centres in Europe. These guidelines are the result of a consensus procedure, in which representatives of the European Sleep Research Society (ESRS) and representatives of different European National Sleep Societies (ENSS) were involved. The information obtained during different rounds of consultation was gathered and processed by the members of the Steering Committee of the ESRS. The scope of the guidelines is to define the characteristics of multidisciplinary Sleep Medicine Centres (SMCs), in terms of requirements regarding staff, operational procedures and logistic facilities. Accreditation of SMCs is proposed to be the responsibility of the individual ENSS. The Accreditation Guidelines may thus be considered an instrument for the national societies to develop new or standardize existing accreditation questionnaires, as well as procedures for visiting the site, drafting the accreditation report, and finally, granting the accreditation. The Accreditation Guidelines are meant to be a line of action, that ideally should be followed as close as possible, but that may be subject to certain exceptions, depending on local customs or regulations. PMID:16704580

  15. A new paradigm for improved co-ordination and efficacy of European biomedical research: taking diabetes as a model.

    PubMed

    Halban, P A; Boulton, A J M; Smith, U

    2013-03-01

    Today, European biomedical and health-related research is insufficiently well funded and is fragmented, with no common vision, less-than-optimal sharing of resources, and inadequate support and training in clinical research. Improvements to the competitiveness of European biomedical research will depend on the creation of new infrastructures that must be dynamic and free of bureaucracy, involve all stakeholders and facilitate faster delivery of new discoveries from bench to bedside. Taking diabetes research as the model, a new paradigm for European biomedical research is presented, which offers improved co-ordination and common resources that will benefit both academic and industrial clinical research. This includes the creation of a European Council for Health Research, first proposed by the Alliance for Biomedical Research in Europe, which will bring together and consult with all health stakeholders to develop strategic and multidisciplinary research programmes addressing the full innovation cycle. A European Platform for Clinical Research in Diabetes is proposed by the Alliance for European Diabetes Research (EURADIA) in response to the special challenges and opportunities presented by research across the European region, with the need for common standards and shared expertise and data. PMID:23238786

  16. [Operational Management of Multidisciplinary Organ-Based Tumor Units in Our Cancer Center].

    PubMed

    Kato, Hiroaki; Tsujie, Masanori; Ichimura, Noriko; Yukawa, Masao; Inoue, Masatoshi

    2016-05-01

    Owing to the advances in diagnosis and treatment, it is imperative to develop a multidisciplinary approach for the management of cancer patients. In our cancer center, multidisciplinary organ-based tumor units have been organized for team medical care. These units consist of cancer specialists from multiple departments including medical oncology, surgery, radiology, histopathology, and nursing. Members of each unit regularly conduct meetings to discuss diagnostic and therapeutic aspects, as well as to report the progress of cancer patients. Co-operation with the counseling and support center, utilization of the computerized medical record system, and using brochures for advertisement, all play important roles in adequate management of multidisciplinary organ-based tumor units. PMID:27210090

  17. Multidisciplinary Design Optimization Techniques: Implications and Opportunities for Fluid Dynamics Research

    NASA Technical Reports Server (NTRS)

    Zang, Thomas A.; Green, Lawrence L.

    1999-01-01

    A challenge for the fluid dynamics community is to adapt to and exploit the trend towards greater multidisciplinary focus in research and technology. The past decade has witnessed substantial growth in the research field of Multidisciplinary Design Optimization (MDO). MDO is a methodology for the design of complex engineering systems and subsystems that coherently exploits the synergism of mutually interacting phenomena. As evidenced by the papers, which appear in the biannual AIAA/USAF/NASA/ISSMO Symposia on Multidisciplinary Analysis and Optimization, the MDO technical community focuses on vehicle and system design issues. This paper provides an overview of the MDO technology field from a fluid dynamics perspective, giving emphasis to suggestions of specific applications of recent MDO technologies that can enhance fluid dynamics research itself across the spectrum, from basic flow physics to full configuration aerodynamics.

  18. Learning mechanisms in multidisciplinary teamwork with real customers and open-ended problems

    NASA Astrophysics Data System (ADS)

    Heikkinen, Juho; Isomöttönen, Ville

    2015-11-01

    Recently, there has been a trend towards adding a multidisciplinary or multicultural element to traditional monodisciplinary project courses in computing and engineering. In this article, we examine the implications of multidisciplinarity for students' learning experiences during a one-semester project course for real customers. We use a qualitative research approach and base our analysis on students' learning reports on three instances of a project course titled Multidisciplinary working life project. The main contribution of this article is the unified theoretical picture of the learning mechanisms stemming from multidisciplinarity. Our main conclusions are that (1) students generally have a positive view of multidisciplinarity; (2) multidisciplinary teams enable students to better identify their own expertise, which leads to increased occupational identity; and (3) learning experiences are not fixed, as team spirit and student attitude play an important role in how students react to challenging situations arising from introduction of the multidisciplinarity.

  19. Development and Application of the Collaborative Optimization Architecture in a Multidisciplinary Design Environment

    NASA Technical Reports Server (NTRS)

    Braun, R. D.; Kroo, I. M.

    1995-01-01

    Collaborative optimization is a design architecture applicable in any multidisciplinary analysis environment but specifically intended for large-scale distributed analysis applications. In this approach, a complex problem is hierarchically de- composed along disciplinary boundaries into a number of subproblems which are brought into multidisciplinary agreement by a system-level coordination process. When applied to problems in a multidisciplinary design environment, this scheme has several advantages over traditional solution strategies. These advantageous features include reducing the amount of information transferred between disciplines, the removal of large iteration-loops, allowing the use of different subspace optimizers among the various analysis groups, an analysis framework which is easily parallelized and can operate on heterogenous equipment, and a structural framework that is well-suited for conventional disciplinary organizations. In this article, the collaborative architecture is developed and its mathematical foundation is presented. An example application is also presented which highlights the potential of this method for use in large-scale design applications.

  20. Multidisciplinary High-Fidelity Analysis and Optimization of Aerospace Vehicles. Part 2; Preliminary Results

    NASA Technical Reports Server (NTRS)

    Walsh, J. L.; Weston, R. P.; Samareh, J. A.; Mason, B. H.; Green, L. L.; Biedron, R. T.

    2000-01-01

    An objective of the High Performance Computing and Communication Program at the NASA Langley Research Center is to demonstrate multidisciplinary shape and sizing optimization of a complete aerospace vehicle configuration by using high-fidelity finite-element structural analysis and computational fluid dynamics aerodynamic analysis in a distributed, heterogeneous computing environment that includes high performance parallel computing. A software system has been designed and implemented to integrate a set of existing discipline analysis codes, some of them computationally intensive, into a distributed computational environment for the design of a high-speed civil transport configuration. The paper describes both the preliminary results from implementing and validating the multidisciplinary analysis and the results from an aerodynamic optimization. The discipline codes are integrated by using the Java programming language and a Common Object Request Broker Architecture compliant software product. A companion paper describes the formulation of the multidisciplinary analysis and optimization system.

  1. Development of a Multi-Disciplinary Aerothermostructural Model Applicable to Hypersonic Flight

    NASA Technical Reports Server (NTRS)

    Kostyk, Chris; Risch, Tim

    2013-01-01

    The harsh and complex hypersonic flight environment has driven design and analysis improvements for many years. One of the defining characteristics of hypersonic flight is the coupled, multi-disciplinary nature of the dominant physics. In an effect to examine some of the multi-disciplinary problems associated with hypersonic flight engineers at the NASA Dryden Flight Research Center developed a non-linear 6 degrees-of-freedom, full vehicle simulation that includes the necessary model capabilities: aerothermal heating, ablation, and thermal stress solutions. Development of the tool and results for some investigations will be presented. Requirements and improvements for future work will also be reviewed. The results of the work emphasize the need for a coupled, multi-disciplinary analysis to provide accurate

  2. Exploration of Fluorine Chemistry at the Multidisciplinary Interface of Chemistry and Biology

    PubMed Central

    Ojima, Iwao

    2013-01-01

    Over the last three decades, my engagement in “fluorine chemistry” has evolved substantially, because of the multidisciplinary nature of the research programs. I began my research career as a synthetic chemist in organometallic chemistry and homogeneous catalysis directed toward organic synthesis. Then, I was brought into a very unique world of “fluorine chemistry” in the end of 1970s. I started exploring the interface of fluorine chemistry and transition metal homogeneous catalysis first, which was followed by amino acids, peptides, and peptidomimetics for medicinal chemistry. Since then, I have been exploring the interfaces of fluorine chemistry and multidisciplinary fields of research involving medicinal chemistry, chemical biology, cancer biology and molecular imaging. This perspective intends to cover my fruitful endeavor in the exploration of fluorine chemistry at the multidisciplinary interface of chemistry and biology in a chronological order to show the evolution of my research interest and strategy. PMID:23614876

  3. European Citizenship and European Union Expansion: Perspectives on Europeanness and Citizenship Education from Britain and Turkey

    ERIC Educational Resources Information Center

    Wilkins, Chris; Busher, Hugh; Lawson, Tony; Acun, Ismail; Goz, Nur Leman

    2010-01-01

    This article discusses some perspectives on citizenship education in Turkey and Britain in the context of current contested discourses on the nature of European identity and of the European Union (EU). It is based on data collected during an EU-funded student teacher exchange programme between three universities in Turkey and Leicester University…

  4. LUSI LAB: a multidisciplinary project in a natural active laboratory

    NASA Astrophysics Data System (ADS)

    Mazzini, Adriano; Lusi Lab Team

    2016-04-01

    The 29th of May 2006 several gas and mud eruption sites suddenly appeared along a strike-slip fault (Watukosek fault system) in the NE of Java, Indonesia. The eruption occurred almost two days after a 6.3 M earthquake striking the island of Java. Within weeks several villages were submerged by boiling mud. The most prominent eruption site was named Lusi. To date Lusi is still active. This disaster has forced 50.000 people to be evacuated and an area of ~7 km2 is covered by mud. The social impact of the eruption and its spectacular dimensions still attract the attention of international media reporting on the "largest mud eruption site on Earth". LUSI LAB (ERC grant n° 308126) focuses on five main aspects in order to complete a comprehensive regional investigation of this impressive event: 1) sampling and monitoring the active Lusi eruption site; 2) monitoring and sampling the neighbouring volcanic arc; 3) monitoring the local micro-seismicity and its relationship with regional seismicity; 4) monitoring the fault system originating from the volcanic arc, crossing Lusi and extending to the NE of Java island; 5) numerical modelling of Lusi activity and the strike-slip/magmatic complex system. We completed several field expeditions. Our studies investigated the mechanisms of reactivation of the Watukosek fault system that crosses Lusi locality and continues to the NE of Java. Results show that after the 27-05-2009 earthquake it was activated the lateral movement of this strike-slip system resulting in these several aligned eruptions sites including Lusi. Further, our geochemical studies of the erupted fluids reveal a mantle signature and point to a connection with the neighboring Arjuno-Welirang volcanic complex indicating that Lusi is a sedimentary hosted geothermal system. We have designed, developed and constructed the Lusi drone. This is a remote controlled hexacopter developed and assembled in order to complete multidisciplinary studies in extreme and

  5. LUSI LAB: a multidisciplinary project in a natural active laboratory

    NASA Astrophysics Data System (ADS)

    Mazzini, Adriano; Lusi Lab Team

    2016-04-01

    The 29th of May 2006 several gas and mud eruption sites suddenly appeared along a strike-slip fault (Watukosek fault system) in the NE of Java, Indonesia. The eruption occurred almost two days after a 6.3 M earthquake striking the island of Java. Within weeks several villages were submerged by boiling mud. The most prominent eruption site was named Lusi. To date Lusi is still active. This disaster has forced 50.000 people to be evacuated and an area of ~7 km2 is covered by mud. The social impact of the eruption and its spectacular dimensions still attract the attention of international media reporting on the "largest mud eruption site on Earth". LUSI LAB (ERC grant n° 308126) focuses on five main aspects in order to complete a comprehensive regional investigation of this impressive event: 1) sampling and monitoring the active Lusi eruption site; 2) monitoring and sampling the neighbouring volcanic arc; 3) monitoring the local micro-seismicity and its relationship with regional seismicity; 4) monitoring the fault system originating from the volcanic arc, crossing Lusi and extending to the NE of Java island; 5) numerical modelling of Lusi activity and the strike-slip/magmatic complex system. We completed several field expeditions. Our studies investigated the mechanisms of reactivation of the Watukosek fault system that crosses Lusi locality and continues to the NE of Java. Results show that after the 27-05-2009 earthquake it was activated the lateral movement of this strike-slip system resulting in these several aligned eruptions sites including Lusi. Further, our geochemical studies of the erupted fluids reveal a mantle signature and point to a connection with the neighboring Arjuno-Welirang volcanic complex indicating that Lusi is a sedimentary hosted geothermal system. We have designed, developed and constructed the Lusi drone. This is a remote controlled hexacopter developed and assembled in order to complete multidisciplinary studies in extreme and

  6. Predictive factors for the outcome of multidisciplinary treatments in chronic low back pain at the first multidisciplinary pain center of Japan.

    PubMed

    Hayashi, Kazuhiro; Arai, Young-Chang P; Ikemoto, Tatsunori; Nishihara, Makoto; Suzuki, Shigeyuki; Hirakawa, Tomoe; Matsuo, Shingo; Kobayashi, Mami; Haruta, Midori; Kawabata, Yuka; Togo, Hiroki; Noguchi, Taiji; Hase, Toshiyuki; Hatano, Genki; Ushida, Takahiro

    2015-09-01

    [Purpose] Multidisciplinary treatments are recommended for treatment of chronic low back pain. The aim of this study was to show the associations among multidisciplinary treatment outcomes, pretreatment psychological factors, self-reported pain levels, and history of pain in chronic low back pain patients. [Subjects and Methods] A total of 221 chronic low back pain patients were chosen for the study. The pretreatment scores for the 10-cm Visual Analogue Scale, Hospital Anxiety and Depression Scale, Pain Catastrophizing Scale, Short-Form McGill Pain Questionnaire, Pain Disability Assessment Scale, pain drawings, and history of pain were collected. The patients were divided into two treatment outcome groups a year later: a good outcome group and a poor outcome group. [Results] One-hundred eighteen patients were allocated to the good outcome group. The scores for the Visual Analogue Scale, Pain Disability Assessment Scale, and affective subscale of the Short-Form McGill Pain Questionnaire and number of nonorganic pain drawings in the good outcome group were significantly lower than those in the poor outcome group. Duration of pain in the good outcome group was significantly shorter than in the poor outcome group. [Conclusion] These findings help better predict the efficacy of multidisciplinary treatments in chronic low back pain patients. PMID:26504321

  7. Predictive factors for the outcome of multidisciplinary treatments in chronic low back pain at the first multidisciplinary pain center of Japan

    PubMed Central

    Hayashi, Kazuhiro; Arai, Young-Chang P.; Ikemoto, Tatsunori; Nishihara, Makoto; Suzuki, Shigeyuki; Hirakawa, Tomoe; Matsuo, Shingo; Kobayashi, Mami; Haruta, Midori; Kawabata, Yuka; Togo, Hiroki; Noguchi, Taiji; Hase, Toshiyuki; Hatano, Genki; Ushida, Takahiro

    2015-01-01

    [Purpose] Multidisciplinary treatments are recommended for treatment of chronic low back pain. The aim of this study was to show the associations among multidisciplinary treatment outcomes, pretreatment psychological factors, self-reported pain levels, and history of pain in chronic low back pain patients. [Subjects and Methods] A total of 221 chronic low back pain patients were chosen for the study. The pretreatment scores for the 10-cm Visual Analogue Scale, Hospital Anxiety and Depression Scale, Pain Catastrophizing Scale, Short-Form McGill Pain Questionnaire, Pain Disability Assessment Scale, pain drawings, and history of pain were collected. The patients were divided into two treatment outcome groups a year later: a good outcome group and a poor outcome group. [Results] One-hundred eighteen patients were allocated to the good outcome group. The scores for the Visual Analogue Scale, Pain Disability Assessment Scale, and affective subscale of the Short-Form McGill Pain Questionnaire and number of nonorganic pain drawings in the good outcome group were significantly lower than those in the poor outcome group. Duration of pain in the good outcome group was significantly shorter than in the poor outcome group. [Conclusion] These findings help better predict the efficacy of multidisciplinary treatments in chronic low back pain patients. PMID:26504321

  8. Europeans: an endangered species?

    PubMed

    Von Cube, A

    1986-10-01

    Below replacement fertility has become the norm in 21 of Europe's 27 countries. Their average total fertility rate is 1.69. This trend has raised concerns about insufficient numbers in the economically active population and prospective personnel shortages in the military. In the Federal Republic of Germany, fertility has been below replacement for the past 17 years and its 1985 total fertility rate of 1.28 is a record low. Only a few European countries (Bulgaria, France, and Romania) have explicitly pronatalist policies. Other nations (Belgium, Finland, Luxembourg, and the German Democratic Republic) have instituted a progressive system of child allowances, increasing payments with each additional birth. Ironically, policies that seek to promote social opportunities for women, such as participation in the labor force, are likely to reduce fertility even farther. Without increased services such as reasonably priced housing, child care centers, and economic incentives to compensate women for lost opportunity costs in the labor market, policies that seek to increase fertility will not succeed. Policy options that were once available to increase fertility (for example, prohibiting abortion) are no longer socially acceptable. New policies will have to be developed through research on the determinants of fertility behavior in postindustrial societies. PMID:12315251

  9. The Victorian Melanoma Service: A 20-year review of an Australian multidisciplinary cancer service.

    PubMed

    Meani, Rowena E; Pan, Yan; McLean, Catriona; Haydon, Andrew; Leung, Michael; Kelly, John W

    2016-08-01

    Australia has the highest incidence and mortality rates for melanoma in the world. The Victorian Melanoma Service began operation in 1994 as one of the first multidisciplinary melanoma clinics in Victoria. We conducted a review of the Victorian Melanoma Service database of 6721 patients and present the trends observed in a statewide referral centre in Australia. Our results highlight the importance of multidisciplinary care of melanoma patients and emphasise the significance of histological reviews and dermatological skin assessments for the detection of synchronous melanoma. PMID:26559638

  10. Application of advanced multidisciplinary analysis and optimization methods to vehicle design synthesis

    NASA Technical Reports Server (NTRS)

    Consoli, Robert David; Sobieszczanski-Sobieski, Jaroslaw

    1990-01-01

    Advanced multidisciplinary analysis and optimization methods, namely system sensitivity analysis and non-hierarchical system decomposition, are applied to reduce the cost and improve the visibility of an automated vehicle design synthesis process. This process is inherently complex due to the large number of functional disciplines and associated interdisciplinary couplings. Recent developments in system sensitivity analysis as applied to complex non-hierarchic multidisciplinary design optimization problems enable the decomposition of these complex interactions into sub-processes that can be evaluated in parallel. The application of these techniques results in significant cost, accuracy, and visibility benefits for the entire design synthesis process.

  11. Multidisciplinary lung cancer meetings: improving the practice of radiation oncology and facing future challenges.

    PubMed

    Campbell, Belinda A; Ball, David; Mornex, Françoise

    2015-02-01

    Clinical guidelines widely recognize the importance of multidisciplinary meetings (MDM) in the optimal care of lung cancer patients. The published literature suggest that dedicated Lung Cancer MDM lead to increased treatment utilization rates and improved survival outcomes for patients with lung cancer. For radiation oncologists, Lung Cancer MDM have been proven to support evidence-based practice and improve the utilization of radiotherapy. Lung Cancer MDM also allow for education and promotion of specialty radiotherapy services. The fast pace of modern medicine is also presenting new challenges for the multidisciplinary lung cancer team, and technological advances are likely to lead to new changes in the structure of traditional Lung Cancer MDM. PMID:25581058

  12. Establishing a multidisciplinary diabetic foot team in a large tertiary hospital: a workshop.

    PubMed

    Cahn, Avivit; Elishuv, Ofer; Olshtain-Pops, Keren

    2014-07-01

    Every year, over 1 million people with diabetes lose a leg due to diabetic foot disease. Most amputations are preceded by a foot ulcer. Causes for the development of foot ulcers are generally multifactorial and may include neuropathy, peripheral vasculopathy, abnormal foot mechanics and infection. Multidisciplinary approach to the patient with acute diabetic foot is mandatory and has been shown to reduce amputation rate. In our article we describe the establishment of a multidisciplinary diabetic foot team in a large tertiary hospital and its outcomes. PMID:24446250

  13. Proposal of a model for multidisciplinary treatment program of chronic migraine with medication overuse: preliminary study.

    PubMed

    Grazzi, L; Prunesti, A; Bussone, G

    2015-05-01

    The treatment of patients with chronic migraine associated with medication overuse is challenging in clinical practice; different strategies of treatment have been recently developed, multidisciplinary treatment approaches have been developed in academic headache centers. Education and support of patients are necessary to improve patients' adherence to pharmacological treatments as well as to non-pharmacological therapies. This study reports a clinical experience conducted at our Headache center with a group of female patients, suffering from chronic migraine complicated by medication overuse, treated by a multidisciplinary approach and followed for a period of 1 year after withdrawal. Results confirm the efficacy of a multifaceted treatment to manage this problematic category of patients. PMID:26017536

  14. Multidisciplinary Design, Analysis, and Optimization Tool Development using a Genetic Algorithm

    NASA Technical Reports Server (NTRS)

    Pak, Chan-gi; Li, Wesley

    2008-01-01

    Multidisciplinary design, analysis, and optimization using a genetic algorithm is being developed at the National Aeronautics and Space A dministration Dryden Flight Research Center to automate analysis and design process by leveraging existing tools such as NASTRAN, ZAERO a nd CFD codes to enable true multidisciplinary optimization in the pr eliminary design stage of subsonic, transonic, supersonic, and hypers onic aircraft. This is a promising technology, but faces many challe nges in large-scale, real-world application. This paper describes cur rent approaches, recent results, and challenges for MDAO as demonstr ated by our experience with the Ikhana fire pod design.

  15. European Neutron Activation System.

    Energy Science and Technology Software Center (ESTSC)

    2013-01-11

    Version 03 EASY-2010 (European Activation System) consists of a wide range of codes, data and documentation all aimed at satisfying the objective of calculating the response of materials irradiated in a neutron flux. The main difference from the previous version is the upper energy limit, which has increased from 20 to 60 MeV. It is designed to investigate both fusion devices and accelerator based materials test facilities that will act as intense sources of high-energymore » neutrons causing significant activation of the surrounding materials. The very general nature of the calculational method and the data libraries means that it is applicable (with some reservations) to all situations (e.g. fission reactors or neutron sources) where materials are exposed to neutrons below 60 MeV. EASY can be divided into two parts: data and code development tools and user tools and data. The former are required to develop the latter, but EASY users only need to be able to use the inventory code FISPACT and be aware of the contents of the EAF library (the data source). The complete EASY package contains the FISPACT-2007 inventory code, the EAF-2003, EAF-2005, EAF-2007 and EAF-2010 libraries, and the EASY User Interface for the Window version. The activation package EASY-2010 is the result of significant development to extend the upper energy range from 20 to 60 MeV so that it is capable of being used for IFMIF calculations. The EAF-2010 library contains 66,256 reactions, almost five times more than in EAF-2003 (12,617). Deuteron-induced and proton-induced cross section libraries are also included, and can be used with EASY to enable calculations of the activation due to deuterons and proton [2].« less

  16. European MEMS foundries

    NASA Astrophysics Data System (ADS)

    Salomon, Patric R.

    2003-01-01

    According to the latest release of the NEXUS market study, the market for MEMS or Microsystems Technology (MST) is predicted to grow to $68B by the year 2005, with systems containing these components generating even higher revenues and growth. The latest advances in MST/MEMS technology have enabled the design of a new generation of microsystems that are smaller, cheaper, more reliable, and consume less power. These integrated systems bring together numerous analog/mixed signal microelectronics blocks and MEMS functions on a single chip or on two or more chips assembled within an integrated package. In spite of all these advances in technology and manufacturing, a system manufacturer either faces a substantial up-front R&D investment to create his own infrastructure and expertise, or he can use design and foundry services to get the initial product into the marketplace fast and with an affordable investment. Once he has a viable product, he can still think about his own manufacturing efforts and investments to obtain an optimized high volume manufacturing for the specific product. One of the barriers to successful exploitation of MEMS/MST technology has been the lack of access to industrial foundries capable of producing certified microsystems devices in commercial quantities, including packaging and test. This paper discusses Multi-project wafer (MPW) runs, requirements for foundries and gives some examples of foundry business models. Furthermore, this paper will give an overview on MST/MEMS services that are available in Europe, including pure commercial activities, European project activities (e.g. Europractice), and some academic services.

  17. The European Project Semester at ISEP: the challenge of educating global engineers

    NASA Astrophysics Data System (ADS)

    Malheiro, Benedita; Silva, Manuel; Ribeiro, Maria Cristina; Guedes, Pedro; Ferreira, Paulo

    2015-05-01

    Current engineering education challenges require approaches that promote scientific, technical, design and complementary skills while fostering autonomy, innovation and responsibility. The European Project Semester (EPS) at Instituto Superior de Engenharia do Porto (ISEP) (EPS@ISEP) is a one semester project-based learning programme (30 European Credit Transfer Units (ECTU)) for engineering students from diverse scientific backgrounds and nationalities that intends to address these goals. The students, organised in multidisciplinary and multicultural teams, are challenged to solve real multidisciplinary problems during one semester. The EPS package, although on project development (20 ECTU), includes a series of complementary seminars aimed at fostering soft, project-related and engineering transversal skills (10 ECTU). Hence, the students enrolled in this programme improve their transversal skills and learn, together and with the team of supervisors, subjects distinct from their core training. This paper presents the structure, implementation and results of the EPS@ISEP that was created in 2011 to apply the best engineering practices and promote internationalisation and engineering education innovation at ISEP.

  18. [French European military haemovigilance guidelines].

    PubMed

    Sailliol, A; Clavier, B; Cap, A; Ausset, S

    2010-12-01

    European military transfusion services follow operational guidelines established by their respective national health systems and conform with European Union directives and NATO standards as applicable to member countries. Certain features are common to all of these standards, especially the pre-selection of volunteer, almost exclusively unpaid donors. NATO requirements are very close to European guidelines, with the exception that NATO permits the use of blood products collected in emergency conditions in theater when circumstances allow no better option. Blood product traceability exists for every country but is not always centralized or computerized. Serious adverse event reporting relies on national haemovigilance networks. Military considerations become important mainly in overseas operations, where the overall policy is to implement the relevant national, European or NATO guidelines with adjustments made for unique wartime circumstances and the risk/benefit ratio for the individual patient needing a transfusion. PMID:21051263

  19. [European general practice research agenda].

    PubMed

    Mäntyselkä, Pekka; Koskela, Tuomas

    2014-01-01

    The EGPRN (European General Practice Research Network) research agenda is a review compiling the strengths and areas of development of European general practice, based on a systematic literature survey and its versatile analysis. The research agenda is a framework paper sharpening the definition and functions of general practice as well as its significance for researchers and decisionmakers. The agenda is useful in structuring the research, evaluation of research needs, strengthening of infrastructure and strategic planning of new research. PMID:24961062

  20. Earthquake induced landslide hazard: a multidisciplinary field observatory in the Marmara SUPERSITE

    NASA Astrophysics Data System (ADS)

    Bigarré, Pascal

    2014-05-01

    Earthquake-triggered landslides have an increasing disastrous impact in seismic regions due to the fast growing urbanization and infrastructures. Just considering disasters from the last fifteen years, among which the 1999 Chi-Chi earthquake, the 2008 Wenchuan earthquake, and the 2011 Tohoku earthquake, these events generated tens of thousands of coseismic landslides. Those resulted in amazing death toll and considerable damages, affecting the regional landscape including its hydrological main features. Despite a strong impetus in research during past decades, knowledge on those geohazards is still fragmentary, while databases of high quality observational data are lacking. These phenomena call for further collaborative researches aiming eventually to enhance preparedness and crisis management. As one of the three SUPERSITE concept FP7 projects dealing with long term high level monitoring of major natural hazards at the European level, the MARSITE project gathers research groups in a comprehensive monitoring activity developed in the Sea of Marmara Region, one of the most densely populated parts of Europe and rated at high seismic risk level since the 1999 Izmit and Duzce devastating earthquakes. Besides the seismic threat, landslides in Turkey and in this region constitute an important source of loss. The 1999 Earthquake caused extensive landslides while tsunami effects were observed during the post-event surveys in several places along the coasts of the Izmit bay. The 6th Work Package of MARSITE project gathers 9 research groups to study earthquake-induced landslides focusing on two sub-regional areas of high interest. First, the Cekmece-Avcilar peninsula, located westwards of Istanbul, is a highly urbanized concentrated landslide prone area, showing high susceptibility to both rainfalls while affected by very significant seismic site effects. Second, the off-shore entrance of the Izmit Gulf, close to the termination of the surface rupture of the 1999 earthquake