Sample records for erythrina speciosa andrews

  1. Ultrastructure and post-floral secretion of the pericarpial nectaries of Erythrina speciosa (Fabaceae)

    PubMed Central

    Paiva, Elder Antônio Sousa

    2009-01-01

    Background and Aims The occurrence of nectaries in fruits is restricted to a minority of plant families and consistent reports of their occurrence are not found associated with Fabaceae, mainly showing cellular details. The present study aims to describe the anatomical organization and ultrastructure of the pericarpial nectaries (PNs) in Erythrina speciosa, a bird-pollinated species, discussing functional aspects of these unusual structures. Methods Samples of floral buds, ovaries of flowers at anthesis and fruits at several developmental stages were fixed and processed by the usual methods for studies using light, and scanning and transmission electron microscopy. Nectar samples collected by filter paper wicks were subjected to chemical analysis using thin-layer chromatography. Key Results The PNs are distributed in isolation on the exocarp. Each PN is represented by a single hyaline trichome that consists of a basal cell at epidermal level, stalk cell(s) and a small secretory multicellular head. The apical stalk cell shows inner periclinal and anticlinal walls impregnated by lipids and lignin and has dense cytoplasm with a prevalence of mitochondria and endoplasmic reticulum. The secretory cells show voluminous nuclei and dense cytoplasm, which predominantly has dictyosomes, rough endoplasmic reticulum, plastids, mitochondria and free ribosomes. At the secretory stage the periplasmic space is prominent and contains secretion residues. Tests for sugar indicate the presence of non-reducing sugars in the secretory cells. Nectar samples from PNs contained sucrose, glucose and fructose. Conclusions The secretory stage of these PNs extends until fruit maturation and evidence suggests that the energetic source of nectar production is based on pericarp photosynthesis. Patrolling ants were seen foraging on fruits during all stages of fruit development, which suggests that the PNs mediate a symbiotic relationship between ants and plant, similar to the common role of many

  2. Ultrastructure and post-floral secretion of the pericarpial nectaries of Erythrina speciosa (Fabaceae).

    PubMed

    Paiva, Elder Antônio Sousa

    2009-10-01

    The occurrence of nectaries in fruits is restricted to a minority of plant families and consistent reports of their occurrence are not found associated with Fabaceae, mainly showing cellular details. The present study aims to describe the anatomical organization and ultrastructure of the pericarpial nectaries (PNs) in Erythrina speciosa, a bird-pollinated species, discussing functional aspects of these unusual structures. Samples of floral buds, ovaries of flowers at anthesis and fruits at several developmental stages were fixed and processed by the usual methods for studies using light, and scanning and transmission electron microscopy. Nectar samples collected by filter paper wicks were subjected to chemical analysis using thin-layer chromatography. The PNs are distributed in isolation on the exocarp. Each PN is represented by a single hyaline trichome that consists of a basal cell at epidermal level, stalk cell(s) and a small secretory multicellular head. The apical stalk cell shows inner periclinal and anticlinal walls impregnated by lipids and lignin and has dense cytoplasm with a prevalence of mitochondria and endoplasmic reticulum. The secretory cells show voluminous nuclei and dense cytoplasm, which predominantly has dictyosomes, rough endoplasmic reticulum, plastids, mitochondria and free ribosomes. At the secretory stage the periplasmic space is prominent and contains secretion residues. Tests for sugar indicate the presence of non-reducing sugars in the secretory cells. Nectar samples from PNs contained sucrose, glucose and fructose. The secretory stage of these PNs extends until fruit maturation and evidence suggests that the energetic source of nectar production is based on pericarp photosynthesis. Patrolling ants were seen foraging on fruits during all stages of fruit development, which suggests that the PNs mediate a symbiotic relationship between ants and plant, similar to the common role of many extrafloral nectaries.

  3. Systemically Applied Insecticides for Treatment of Erythrina Gall Wasp, Quadrastichus erythrinae Kim (Hymenoptera: Eulophidae)

    Treesearch

    Joseph J. Doccola; Sheri L. Smith; Brian L. Strom; Arthur C. Medeiros; Erica von Allmen

    2009-01-01

    The erythrina gall wasp (EGW), believed native to Africa, is a recently described species and now serious invasive pest of Erythrina (coral trees) in tropical and subtropical locales. Erythrina are favored ornamental and landscape trees, as well as native members of threatened ecosystems. The EGW is a tiny, highly mobile, highly invasive wasp that deforms (galls) host...

  4. Evaluation of a commercially available ELISA kit for quantifying imidacloprid residues in Erthrina sandwicensis leaves for management of the Erythrina gall wasp, Quadrastichus erythrinae Kim.

    Treesearch

    Joseph Fischer; Brian Strom; Sheri Smith

    2009-01-01

    The erythrina gall wasp (EGW), Quadrastichus erythrinae Kim 2004, was first detected in Hawaii in 2005 and has been infesting and killing Erythrina trees throughout the island chain since. It is believed EGW originated from Africa (Messing et al. 2009). Its host range appears to be limited to Erythrina; its...

  5. Systemically applied insecticides for treatment of erythrina gall wasp, quadrastichus erythrinae kim hymenoptera: Eulophidae

    USGS Publications Warehouse

    Doccola, J.J.; Smith, S.L.; Strom, B.L.; Medeiros, A.C.; Von Allmen, E.

    2009-01-01

    Abstract The erythrina gall wasp (EGW), believed native to Africa, is a recently described species and now serious invasive pest of Erythrina (coral trees) in tropical and subtropical locales. Erythrina are favored ornamental and landscape trees, as well as native members of threatened ecosystems. The EGW is a tiny, highly mobile, highly invasive wasp that deforms (galls) host trees causing severe defoliation and tree death. The first detection of EGW in the United States was in O'ahu, Hawai'i in April 2005. It quickly spread through the Hawai'ian island chain (U.S.) killing ornamental and native Erythrina in as little as two years. At risk are endemic populations of Erythrinaas well as ornamental landscape species in the same genus, the latter of which have already been killed and removed from O'ahu at a cost of more than USD $1 million. Because EGW are so small and spread so quickly, host injury is usually detected before adult wasps are observed, making prophylactic treatments less likely than therapeutic ones. This study evaluates two stem-injected insecticides, imidacloprid (IMA-jet??) and emamectin benzoate, delivered through Arborjet Tree I.V.?? equipment, for their ability to affect E. sandwicensis (wiliwili) canopy demise under severe EGW exposure. IMA-jet, applied at a rate of 0.16 g AI/cm basal diameter (0.4 g AI/in. dia.), was the only effective treatment for maintaining canopy condition of wiliwili trees. Emamectin benzoate, applied at a rate of -0.1 g AI/cm basal diameter (-0.25 g AI/in. dia.), was not effective in this application, although it was intermediate in effect between IMA-jet and untreated trees. The relatively high concentrations of imidacloprid in leaves, and its durability for at least 13 months in native wiliwili growing on a natural, dryland site, suggest that treatment applications against EGW can impact canopy recovery even under suboptimal site and tree conditions. ?? 2009 International Society of Arboriculture.

  6. Chemical Defense by Erythrolactones in the Euryhaline Ciliated Protist, Pseudokeronopsis erythrina.

    PubMed

    Buonanno, Federico; Anesi, Andrea; Giuseppe, Graziano Di; Guella, Graziano; Ortenzi, Claudio

    2017-02-01

    Pseudokeronopsis erythrina produces three new secondary metabolites, erythrolactones A2, B2 and C2, and their respective sulfate esters (A1, B1, C1), the structures of which have been recently elucidated on the basis of NMR spectroscopic data coupled to high resolution mass measurements (HR-MALDI-TOF). An analysis of the discharge of the protozoan pigment granules revealed that the non-sulfonated erythrolactones are exclusively stored in these cortical organelles, which are commonly used by a number of ciliates as chemical weapons in offense/defense interactions with prey and predators. We evaluated the toxic activity of pigment granule discharge on a panel of free-living ciliates and micro-invertebrates, and the activity of each single purified erythrolactone on three ciliate species. We also observed predator-prey interactions of P. erythrina with unicellular and multicellular predators. Experimental results confirm that only P. erythrina cells with discharged pigment granules were preferentially or exclusively hunted and eaten by at least some of its predators, whereas almost all intact (fully pigmented) cells remained alive. Our results indicate that erythrolactones are very effective as a chemical defense in P. erythrina.

  7. Intraspecific diversity in Sinningia speciosa (Gesneriaceae: Sinningieae), and possible origins of the cultivated florist's gloxinia

    PubMed Central

    Zaitlin, David

    2012-01-01

    Background and aims The florist's gloxinia is a familiar houseplant in the Gesneriaceae, the botanical family that includes the African violet (Saintpaulia) and other ornamental species. The gloxinia's wild progenitor is Sinningia speciosa (Lodd.) Hiern, a Brazilian endemic. Although it has been cultivated for almost 200 years, little is known about the genetic diversity in S. speciosa, how the wild populations relate to one another or even where the cultivated forms originated. Using available wild collections, preliminary phenetic and phylogenetic investigations were conducted to elucidate the interspecific relationships within S. speciosa and to infer the origins of the cultivars. Methodology Amplified fragment length polymorphism (AFLP) analysis was applied to 24 accessions of S. speciosa (17 wild collections, seven cultivars) and one accession each of Sinningia guttata and Sinningia macrophylla. A maximum likelihood (ML) tree was also calculated from an alignment of the nuclear ribosomal internal transcribed spacer sequence from the same 26 accessions. Principal results Dice/UPGMA and principal coordinates analysis of the AFLP data partitioned S. speciosa into several distinct clusters, one of which included S. macrophylla. All cultivated ‘gloxinias’ grouped together in a major cluster with plants from Rio de Janeiro. The AFLP results were compared with a phylogenetic analysis of the ribosomal spacer region, which was informative in S. speciosa. The ML tree generally supported the AFLP results, although several clades lacked strong statistical support. Conclusions Independent analyses of two different data sets show that S. speciosa is a diverse species comprised of several lineages. Genetic distance estimates calculated from the AFLP data were positively correlated with geographic distances between populations, indicating that reproductive isolation could be driving speciation in this taxon. Molecular markers are under development for population genetic

  8. Assessing sub-Saharan Erythrina for efficacy: traditional uses, biological activities and phytochemistry.

    PubMed

    Kone, Witabouna Mamidou; Solange, Kakou-Ngazoa E; Dosso, Mireille

    2011-05-15

    The genus Erythrina comprises more than 100 species, widely distributed in tropical and subtropical areas. In Africa, 31 wild species and 14 cultivated species have been described. In sub-Saharan Africa, Erythrina species are used to treat frequent parasitic and microbial diseases, inflammation, cancer, wounds. The rationale of these traditional uses in African traditional medicine was established by screening several species for biological activities. Promising activities were found against bacteria, parasites (Plasmodium), human and phytopathogenic fungi, some of which were multidrug resistant (MDR) micro organisms. Some species also exhibited antioxidant, anti-inflammatory activities and enzymes inhibitory properties. Most of the species chemically investigated were reported to contain flavanones, prenylated isoflavones, isoflavanones and pterocarpans. Some phytochemicals (vogelin B, vogelin C, isowightcone, abyssinin II, derrone) were the active principles as antibacterials, antifungals, antiplasmodials and inhibitors of enzyme borne diseases (PTP1B, HIV protease, DGAT). This review highlights the important role of Erythrina species as sources of lead compounds or new class of phytotherapeutic agents for fighting against major public health (MDR infections, cancer, diabetes, obesity) in sub-Saharan Africa.

  9. Beneficial Insect Attraction to Milkweeds (Asclepias speciosa, Asclepias fascicularis) in Washington State, USA

    PubMed Central

    James, David G.; Seymour, Lorraine; Lauby, Gerry; Buckley, Katie

    2016-01-01

    Native plant and beneficial insect associations are relatively unstudied yet are important in native habitat restoration programs for improving and sustaining conservation biological control of arthropod pests in agricultural crops. Milkweeds (Asclepias spp.) are currently the focus of restoration programs in the USA aimed at reversing a decline in populations of the milkweed-dependent monarch butterfly (Danaus plexippus); however, little is known of the benefits of these plants to other beneficial insects. Beneficial insects (predators, parasitoids, pollinators) attracted to two milkweed species (Asclepias speciosa, Asclepias fascicularis) in central Washington State, WA, USA were identified and counted on transparent sticky traps attached to blooms over five seasons. Combining all categories of beneficial insects, means of 128 and 126 insects per trap were recorded for A. speciosa and A. fascicularis, respectively. Predatory and parasitic flies dominated trap catches for A. speciosa while parasitic wasps were the most commonly trapped beneficial insects on A. fascicularis. Bees were trapped commonly on both species, especially A. speciosa with native bees trapped in significantly greater numbers than honey bees. Beneficial insect attraction to A. speciosa and A. fascicularis was substantial. Therefore, these plants are ideal candidates for habitat restoration, intended to enhance conservation biological control, and for pollinator conservation. In central Washington, milkweed restoration programs for enhancement of D. plexippus populations should also provide benefits for pest suppression and pollinator conservation. PMID:27367733

  10. Beneficial Insect Attraction to Milkweeds (Asclepias speciosa, Asclepias fascicularis) in Washington State, USA.

    PubMed

    James, David G; Seymour, Lorraine; Lauby, Gerry; Buckley, Katie

    2016-06-29

    Native plant and beneficial insect associations are relatively unstudied yet are important in native habitat restoration programs for improving and sustaining conservation biological control of arthropod pests in agricultural crops. Milkweeds (Asclepias spp.) are currently the focus of restoration programs in the USA aimed at reversing a decline in populations of the milkweed-dependent monarch butterfly (Danaus plexippus); however, little is known of the benefits of these plants to other beneficial insects. Beneficial insects (predators, parasitoids, pollinators) attracted to two milkweed species (Asclepias speciosa, Asclepias fascicularis) in central Washington State, WA, USA were identified and counted on transparent sticky traps attached to blooms over five seasons. Combining all categories of beneficial insects, means of 128 and 126 insects per trap were recorded for A. speciosa and A. fascicularis, respectively. Predatory and parasitic flies dominated trap catches for A. speciosa while parasitic wasps were the most commonly trapped beneficial insects on A. fascicularis. Bees were trapped commonly on both species, especially A. speciosa with native bees trapped in significantly greater numbers than honey bees. Beneficial insect attraction to A. speciosa and A. fascicularis was substantial. Therefore, these plants are ideal candidates for habitat restoration, intended to enhance conservation biological control, and for pollinator conservation. In central Washington, milkweed restoration programs for enhancement of D. plexippus populations should also provide benefits for pest suppression and pollinator conservation.

  11. The draft genome of Ruellia speciosa (Beautiful Wild Petunia: Acanthaceae).

    PubMed

    Zhuang, Yongbin; Tripp, Erin A

    2017-04-01

    The genus Ruellia (Wild Petunias; Acanthaceae) is characterized by an enormous diversity of floral shapes and colours manifested among closely related species. Using Illumina platform, we reconstructed the draft genome of Ruellia speciosa, with a scaffold size of 1,021 Mb (or ∼1.02 Gb) and an N50 size of 17,908 bp, spanning ∼93% of the estimated genome (∼1.1 Gb). The draft assembly predicted 40,124 gene models and phylogenetic analyses of four key enzymes involved in anthocyanin colour production [flavanone 3-hydroxylase (F3H), flavonoid 3'-hydroxylase (F3'H), flavonoid 3',5'-hydroxylase (F3'5'H), and dihydroflavonol 4-reductase (DFR)] found that most angiosperms here sampled harboured at least one copy of F3H, F3'H, and DFR. In contrast, fewer than one-half (but including R. speciosa) harboured a copy of F3'5'H, supporting observations that blue flowers and/or fruits, which this enzyme is required for, are less common among flowering plants. Ka/Ks analyses of duplicated copies of F3'H and DFR in R. speciosa suggested purifying selection in the former but detected evidence of positive selection in the latter. The genome sequence and annotation of R. speciosa represents only one of only four families sequenced in the large and important Asterid clade of flowering plants and, as such, will facilitate extensive future research on this diverse group, particularly with respect to floral evolution. © The Author 2017. Published by Oxford University Press on behalf of Kazusa DNA Research Institute.

  12. The draft genome of Ruellia speciosa (Beautiful Wild Petunia: Acanthaceae)

    PubMed Central

    Zhuang, Yongbin

    2017-01-01

    Abstract The genus Ruellia (Wild Petunias; Acanthaceae) is characterized by an enormous diversity of floral shapes and colours manifested among closely related species. Using Illumina platform, we reconstructed the draft genome of Ruellia speciosa, with a scaffold size of 1,021 Mb (or ∼1.02 Gb) and an N50 size of 17,908 bp, spanning ∼93% of the estimated genome (∼1.1 Gb). The draft assembly predicted 40,124 gene models and phylogenetic analyses of four key enzymes involved in anthocyanin colour production [flavanone 3-hydroxylase (F3H), flavonoid 3′-hydroxylase (F3′H), flavonoid 3′,5′-hydroxylase (F3′5′H), and dihydroflavonol 4-reductase (DFR)] found that most angiosperms here sampled harboured at least one copy of F3H, F3′H, and DFR. In contrast, fewer than one-half (but including R. speciosa) harboured a copy of F3′5′H, supporting observations that blue flowers and/or fruits, which this enzyme is required for, are less common among flowering plants. Ka/Ks analyses of duplicated copies of F3′H and DFR in R. speciosa suggested purifying selection in the former but detected evidence of positive selection in the latter. The genome sequence and annotation of R. speciosa represents only one of only four families sequenced in the large and important Asterid clade of flowering plants and, as such, will facilitate extensive future research on this diverse group, particularly with respect to floral evolution. PMID:28431014

  13. Anti-inflammatory and analgesic activities of Chaenomeles speciosa fractions in laboratory animals.

    PubMed

    Li, X; Yang, Y-B; Yang, Q; Sun, L-N; Chen, W-S

    2009-10-01

    The prescription of current existing anti-inflammatory drugs is hampered by their adverse effects over time. Botanical extracts are thought to be a potential source of a natural anti-inflammatory property with fewer adverse effects. Chaenomeles speciosa has long been used as an herbal medicine for treatment of various diseases such as rheumatoid arthritis, prosopalgia, and hepatitis. Until now there have been no reports on the specific anti-inflammatory fractions of extract of C. speciosa (ECS). In the present study the anti-inflammatory activities of different fractions of ECS were evaluated using carrageenan-induced paw edema in rats. The 10% ethanol fraction (C3) was found to have stronger anti-inflammatory effects compared with other fractions at the same dose. We also found that chlorogenic acid was one of the active constituents responsible for the anti-inflammatory effect using bioassay-guided fractionation by means of high-performance liquid chromatography. Compared with controls, fraction C3 demonstrated significant anti-inflammatory activity in the xylene-induced ear edema test (P < .01), acetic acid-induced peritoneal capillary permeability test, and the cotton pellet granuloma test in mice or rats (P < .01); it also showed marked analgesic activity in the acetic acid-induced abdominal contraction test and formalin-induced paw licking test in mice and rats (P < .05 or .01). However, fraction C3 showed no significant effect in the hot plate test in mice. These findings justify the use of the C. speciosa for treating pain and inflammation. These results support the proposal of C. speciosa fraction C3 as a potential anti-inflammatory agent.

  14. Identification and Characterization of TALE Homeobox Genes in the Endangered Fern Vandenboschia speciosa

    PubMed Central

    Ruiz-Estévez, Mercedes; Martín-Blázquez, Rubén; Garrido-Ramos, Manuel A.

    2017-01-01

    We report and discuss the results of a quantitative reverse transcription polymerase chain reaction (qRT-PCR) analysis of the expression patterns of seven three amino acid loop extension (TALE) homeobox genes (four KNOTTED-like homeobox (KNOX) and three BEL1-like homeobox (BELL) genes) identified after next generation sequencing (NGS) and assembly of the sporophyte and gametophyte transcriptomes of the endangered fern species Vandenboschia speciosa. Among the four KNOX genes, two belonged to the KNOX1 class and the other two belonged to the KNOX2 class. Analysis of the deduced amino acid sequences supported the typical domain structure of both types of TALE proteins, and the homology to TALE proteins of mosses, lycophytes, and seed plant species. The expression analyses demonstrate that these homeodomain proteins appear to have a key role in the establishment and development of the gametophyte and sporophyte phases of V. speciosa lifecycle, as well as in the control of the transition between both phases. Vandenboschia speciosa VsKNAT3 (a KNOX2 class protein) as well as VsBELL4 and VsBELL10 proteins have higher expression levels during the sporophyte program. On the contrary, one V. speciosa KNOX1 protein (VsKNAT6) and one KNOX2 protein (VsKNAT4) seem important during the development of the gametophyte phase. TALE homeobox genes might be among the key regulators in the gametophyte-to-sporophyte developmental transition in regular populations that show alternation of generations, since some of the genes analyzed here (VsKNAT3, VsKNAT6, VsBELL4, and VsBELL6) are upregulated in a non-alternating population in which only independent gametophytes are found (they grow by vegetative reproduction outside of the range of sporophyte distribution). Thus, these four genes might trigger the vegetative propagation of the gametophyte and the repression of the sexual development in populations composed of independent gametophytes. This study represents a comprehensive

  15. Identification and Characterization of TALE Homeobox Genes in the Endangered Fern Vandenboschia speciosa.

    PubMed

    Ruiz-Estévez, Mercedes; Bakkali, Mohammed; Martín-Blázquez, Rubén; Garrido-Ramos, Manuel A

    2017-10-17

    We report and discuss the results of a quantitative reverse transcription polymerase chain reaction (qRT-PCR) analysis of the expression patterns of seven three amino acid loop extension ( TALE ) homeobox genes (four KNOTTED-like homeobox ( KNOX ) and three BEL1-like homeobox ( BELL ) genes) identified after next generation sequencing (NGS) and assembly of the sporophyte and gametophyte transcriptomes of the endangered fern species Vandenboschia speciosa . Among the four KNOX genes, two belonged to the KNOX1 class and the other two belonged to the KNOX2 class. Analysis of the deduced amino acid sequences supported the typical domain structure of both types of TALE proteins, and the homology to TALE proteins of mosses, lycophytes, and seed plant species. The expression analyses demonstrate that these homeodomain proteins appear to have a key role in the establishment and development of the gametophyte and sporophyte phases of V. speciosa lifecycle, as well as in the control of the transition between both phases. Vandenboschia speciosa VsKNAT3 (a KNOX2 class protein) as well as VsBELL4 and VsBELL10 proteins have higher expression levels during the sporophyte program. On the contrary, one V. speciosa KNOX1 protein (VsKNAT6) and one KNOX2 protein (VsKNAT4) seem important during the development of the gametophyte phase. TALE homeobox genes might be among the key regulators in the gametophyte-to-sporophyte developmental transition in regular populations that show alternation of generations, since some of the genes analyzed here ( VsKNAT3 , VsKNAT6 , VsBELL4 , and VsBELL6 ) are upregulated in a non-alternating population in which only independent gametophytes are found (they grow by vegetative reproduction outside of the range of sporophyte distribution). Thus, these four genes might trigger the vegetative propagation of the gametophyte and the repression of the sexual development in populations composed of independent gametophytes. This study represents a comprehensive

  16. Obituary: Andrew Stephen Wilson, 1947-2008

    NASA Astrophysics Data System (ADS)

    Veilleux, Sylvain

    2009-01-01

    On 24 May 2008, Andrew Stephen Wilson passed away at the age of 61, in his home in Silver Spring, Maryland, from complications resulting from a painful spinal illness. Andrew was arguably one of the first truly multi-wavelength astronomers of his generation. His scientific work on active galactic nuclei [AGN] spanned the entire electromagnetic spectrum from the radio to the X-rays. Andrew was born in Doncaster, Yorkshire, England, on 26 March 1947. He was the younger of two brothers whose births were separated by the Second World War. His father, Norman, came from a relatively affluent family who were coal merchants. His mother, Mary, came from a less comfortable background, one of seven children, daughter of a skilled cabinet maker/French polisher, who went through a very hard time during the depression. As a teacher, she placed enormous value on hard work and education as a way of gaining advancement in life. When Andrew was four, the family moved to Skipton, a nice market town in the Yorkshire dales. Andrew went to a small village school until age eleven when he entered Ermysted's Grammar School. He was an enthusiastic soccer and cricket player. He never lost his enthusiasm for soccer and supported the local soccer team, Leeds United, for all his life. Andrew also followed the Yorkshire county cricket team. Andrew's interest in astronomy stemmed from the fact that at Ermysted's Grammar School someone donated a four-inch refracting telescope, so he and his friends used to go back in the evenings to investigate the rings of Saturn, the moons of Jupiter, and various nebulae. While an undergraduate at Cambridge, Andrew joined the astronomy club and ground an 8-inch mirror by hand as a part of a telescope that he set up in the backyard of his parents' house. Andrew spent hours observing with this telescope, and it was the wonder of the family. At Cambridge, Andrew obtained his bachelor's degree with first-class honors in 1969. During a short visit in London with his

  17. The Impact of Global Climate Change on the Geographic Distribution and Sustainable Harvest of Hancornia speciosa Gomes (Apocynaceae) in Brazil

    NASA Astrophysics Data System (ADS)

    Nabout, João Carlos; Magalhães, Mara Rúbia; de Amorim Gomes, Marcos Aurélio; da Cunha, Hélida Ferreira

    2016-04-01

    The global Climate change may affect biodiversity and the functioning of ecosystems by changing the appropriate locations for the development and establishment of the species. The Hancornia speciosa, popularly called Mangaba, is a plant species that has potential commercial value and contributes to rural economic activities in Brazil. The aim of this study was to evaluate the impact of global climate change on the potential geographic distribution, productivity, and value of production of H. speciosa in Brazil. We used MaxEnt to estimate the potential geographic distribution of the species in current and future (2050) climate scenarios. We obtained the productivity and value of production for 74 municipalities in Brazil. Moreover, to explain the variation the productivity and value of production, we constructed 15 models based on four variables: two ecological (ecological niche model and the presence of Unity of conservation) and two socio-economic (gross domestic product and human developed index). The models were selected using Akaike Information Criteria. Our results suggest that municipalities currently harvesting H. speciosa will have lower harvest rates in the future (mainly in northeastern Brazil). The best model to explain the productivity was ecological niche model; thus, municipalities with higher productivity are inserted in regions with higher environmental suitability (indicated by niche model). Thus, in the future, the municipalities harvesting H. speciosa will produce less because there will be less suitable habitat for H. speciosa, which in turn will affect the H. speciosa harvest and the local economy.

  18. Molecular evidence of undescribed Ceratonova sp. (Cnidaria: Myxosporea) in the freshwater polychaete, Manayunkia speciosa, from western Lake Erie

    USGS Publications Warehouse

    Malakauskas, David M.; Snipes, Robert Benjamin; Thompson, Ann M.; Schloesser, Donald W.

    2016-01-01

    We used PCR to screen pooled individuals of Manayunkia speciosa from western Lake Erie, Michigan, USA for myxosporean parasites. Amplicons from positive PCRs were sequenced and showed a Ceratonova species in an estimated 1.1% (95% CI = 0.46%, 1.8%) of M. speciosa individuals. We sequenced 18S, ITS1, 5.8S, ITS2 and most of the 28S rDNA regions of this Ceratonova sp., and part of the protein-coding EF2 gene. Phylogenetic analyses of ribosomal and EF2 sequences showed the Lake Erie Ceratonova sp. is most similar to, but genetically distinct from, Ceratonova shasta. Marked interspecific polymorphism in all genes examined, including the ITS barcoding genes, along with geographic location suggests this is an undescribed Ceratonova species. COI sequences showed M. speciosa individuals in Michigan and California are the same species. These findings represent a third parasite in the genus Ceratonovapotentially hosted by M. speciosa.

  19. Stories Along the Way: Andrew

    ERIC Educational Resources Information Center

    Kittle, Penny

    2009-01-01

    Andrew is among the forgotten, the written-off, the hopeless...at least to many of the adults in his life--police, teachers, even family. But when you see that glimmer, that potential, you can't turn your back. Andrew stands as a person, but also a metaphor for believing that each student has a chance to succeed.

  20. H.J. Andrews Experimental Forest.

    Treesearch

    Art McKee; Pamela Druliner

    1998-01-01

    The H.J. Andrews Experimental Forest is a world renowned center for research and education about the ecology and management of forests and streams. Located about 50 miles (80 km) east of Eugene, Oregon, the Andrews Experimental Forest lies in the Blue River Ranger District of the Willamette National Forest. Established in 1948, the Experimental Forest is administered...

  1. A postmenopause-like model of ovariectomized Wistar rats to identify active principles of Erythrina lysistemon (Fabaceae).

    PubMed

    Mvondo, M A; Njamen, D; Fomum, S Tanee; Wandji, J; Vollmer, Günter

    2011-10-01

    To determine whether the two major compounds of Erythrina lysistemon are active principles accounting for Erythrina estrogenic effects, we used a postmenopause-like model of ovariectomized Wistar rats to evaluate their effects on some menopausal problems. Ovariectomized rats were orally treated either with compound 1 or compound 2 at 1 and 10 mg/kg BW for 28 days. Estradiol valerate served as the reference substance. As results, compounds 1 and 2 displayed estrogen-like effects on the uterus and the vagina, and reduced atherogenic risks by decreasing the two assessed atherogenic parameters, the total cholesterol/HDL-cholesterol ratio and the atherogenic index of plasma. Copyright © 2011 Elsevier B.V. All rights reserved.

  2. 76 FR 48168 - Andrew K. Choi: Debarment Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-08

    ...] Andrew K. Choi: Debarment Order AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The... (the FD&C Act) debarring Andrew K. Choi, M.D. for 4 years from providing services in any capacity to a... delegated to him (Staff Manual Guide 1410.35), finds that Andrew K. Choi has been convicted of a misdemeanor...

  3. Bacterial community associated with the trunk latex of Hancornia speciosa Gomes (Apocynaceae) grown in the northeast of Brazil.

    PubMed

    Silva, Thais Freitas da; Coelho, Marcia Reed Rodrigues; Vollú, Renata Estebanez; de Vasconcelos Goulart, Fátima Regina; Alviano, Daniela Sales; Alviano, Celuta Sales; Seldin, Lucy

    2011-03-01

    Prevention or cure of different illnesses through the use of plant latex is a worldwide known concept. The antifungal activity of Hancornia speciosa latex has been observed against Candida albicans. However, H. speciosa latex is not a sterile plant exudate and secondary metabolites produced by bacteria could be involved in fungal inhibition. In the present study, the bacterial communities of the latex from three H. speciosa trees were characterized using traditional plating and molecular methods. Twelve strains isolated from the latex samples were clustered into four groups by amplified ribosomal DNA restriction analysis (ARDRA). One representative of each group was sequenced and they were identified as belonging to the genera Bacillus, Klebsiella, Enterobacter and Escherichia. None of the 12 isolates showed antifungal activity against C. albicans. A lack of a microbial origin for the antifungal properties of latex was noted. DGGE profiles generated from each of the three latex samples showed unique patterns. Sequencing of the DGGE bands demonstrated the affiliation with the genera Klebsiella, Pantoea, Enterobacter and Burkholderia. In addition, clone libraries were generated and the phylogenetic distribution of the 50 analyzed clones was similar to that obtained using DGGE. The presence of some potential pathogens should be considered before using H. speciosa latex in folk medicine.

  4. Evaluation of the osteogenic potential of Hancornia speciosa latex in rat calvaria and its phytochemical profile.

    PubMed

    Dos Santos Neves, Juliana; Franchin, Marcelo; Rosalen, Pedro Luiz; Omar, Nadia Fayez; Dos Santos, Mariana Albuquerque; Paschoal, Jonas Augusto Rizzato; Novaes, Pedro Duarte

    2016-05-13

    Hancornia speciosa Gomes, commonly known as Mangabeira, is a Brazilian native fruit tree belonging to the Apocynaceae family. In folk medicine, the latex obtained from Mangabeira's trunk has been used as an adjunct therapy for bone fractures. Few pharmacological studies on the Hancornia speciosa latex have been developed and despite its popular use for bone healing there is no data about its biological effect on bone. The present study aimed to investigate the osteogenic potential of Hancornia speciosa latex in rat calvaria, as well as its phytochemical profile. A neutral gel composition containing 5% latex was topical applied to a critical size bone defect and over intact calvaria of rats. Areas of newly formed bone on the borders of the defect and of calvaria periosteum were quantified, as well as the percentage of BrdU-positive cells and total cells in the periosteum at different periods of time after latex application. The cytotoxicity of the latex aqueous phase was evaluated in rat calvarial cells in vitro by MTT assay and its phytochemical profile was investigated by ESI-MS/MS. The area of newly formed bone on the borders of the calvaria defect was larger in rats that received latex at 15 and 30 days of healing. After 3 days of latex application over the intact calvaria, the periosteum area was increased and newly formed bone was observed after 5 and 11 days. There was also an increase in periosteum cell proliferation and population followed latex application on calvaria (p<0.05). The latex aqueous phase limited rat calvarial cell viability in vitro in concentrations larger than 0.6mg/mL. Chlorogenic acid and naringenin-7-O-glucoside were identified in the latex aqueous phase, along with catechin and procyanidin compounds. There was a stimulus for periosteum cell proliferation and bone formation when Hancornia speciosa latex was topically applied on rat calvaria. In addition, chlorogenic acid and naringenin-7-O-glucoside present in Hancornia speciosa latex

  5. Radical Scavenging Activities of Lagerstroemia speciosa (L.) Pers. Petal Extracts and its hepato-protection in CCl4-intoxicated mice.

    PubMed

    Tiwary, Bipransh Kumar; Dutta, Somit; Dey, Priyankar; Hossain, Mossaraf; Kumar, Anoop; Bihani, Sony; Nanda, Ashis Kumar; Chaudhuri, Tapas Kumar; Chakraborty, Ranadhir

    2017-01-18

    Lagerstroemia speciosa (L.) Pers. has medicinal importance. Bioactive phytochemicals isolated from different parts of L. speciosa, have revealed hypoglycemic, antibacterial, anti-inflammatory, antioxidant and hepato protective properties. Despite one report from Philippines detailing the use of L. speciosa as curative for fever and as well as diuretic, there is no experimental evidence about the hepatoprotective activity of the flower extracts. Several spectroscopic methods, including GC-MS, were used to characterize phytochemicals present in the petal extract of L. speciosa. Ethanol extract of petals was evaluated for anti-oxidant and free radical scavenging properties by using methods related to hydrogen atom transfer, single electron transfer, reducing power, and metal chelation. This study has also revealed the in vitro antioxidant and in vivo hepatoprotective properties of petal extract against carbon tetra chloride (CCl 4 )-induced liver toxicity in Swiss albino mice. Hepatoprotection in CCl 4 -intoxicated mice was studied with the aid of histology and different enzymatic and non-enzymatic markers of liver damage. Cytotoxicity tests were done using murein spleenocytes and cancareous cell lines, MCF7 and HepG2. GCMS of the extract has revealed the presence of several potential antioxidant compounds, of them γ-Sitosterol and 1,2,3-Benzenetriol (Pyrogallol) were the predominant ones. The antioxidants activities of the flower-extract were significantly higher than curcumin (in terms of Nitric oxide scavenging activity; p = 0.0028) or ascorbic acid (in terms of 2,2-Diphenyl-1-Picrylhydrazyl (DPPH) assay; p = 0.0022). The damage control by the flower extract can be attributed to the reduction in lipid peroxidation and restoration of catalase activity. In vitro cytotoxicity tests have shown that the flower extract did not affect growth and survivability of the cell lines. It left beyond doubt that a flower of L. speciosa is a reservoir of antioxidant and

  6. Early Detection Pest Advisory 2007: Identifying and managing the Erythrina Gall Wasp

    Treesearch

    R-5 and Southern Research Station U.S. Department of Agriculture Forest Service Forest Health Protection

    2007-01-01

    The erythrina gall wasp (EGW) was first detected in the U.S. on Oahu, HI, in April 2005. It was found on the remaining Hawaiian Islands in less than six months and now seriously threatens survival of native coral (wiliwili) trees in Hawaii's dryland forests. The wasp was detected in South Florida in October 2006, further demonstrating its invasive capabilities and...

  7. Obituary: Andrew Lange (1957-2010)

    NASA Astrophysics Data System (ADS)

    Kamionkowski, Marc

    2011-12-01

    The worlds of physics and astrophysics were stunned to learn on 22 January 2010 that Andrew Lange, the Marvin L. Goldberger Professor of Physics at Caltech, had taken his own life the night before. He had succumbed to the severe depression that he had suffered from for many years, unbeknownst to even his closest colleagues. Lange will perhaps be best remembered as the co-leader of Boomerang, the balloon-borne experiment that provided the first high-angular-resolution map of the cosmic microwave background (CMB). And while this was certainly his most notable achievement, Andrew amassed a record of accomplishment as an instrumentalist, leader, mentor, and communicator that extended much further. Andrew was born in Urbana, Illinois on July 23, 1957, the son of an architect and a librarian, and raised primarily in Connecticut. His family and early friends remember him as a serious and extremely intelligent child and young man. Andrew Lange's lifelong interest in the CMB was nurtured as an undergraduate at Princeton University by David Wilkinson, and he recalled fondly a summer spent working with John Mather at Goddard Space Flight Center. Andrew Lange went to graduate school in physics at Berkeley where he worked in Paul Richards' group. Although his thesis project, the Berkeley-Nagoya rocket experiment, showed an anomalous sub-millimeter excess in the CMB spectrum that was shortly thereafter shown by a later flight of the same rocket and COBE-FIRAS to be incorrect, Lange's talents were recognized by the physics department at Berkeley who appointed him shortly after his PhD (1987) to their faculty. While on the Berkeley faculty, Andrew obtained early detections of the Sunyaev-Zeldovich effect, upper limits to small-angle CMB fluctuations, and important infrared constraints to the interstellar medium. He also led a pioneering instrument operating 300 mK detectors for a small infrared satellite experiment. This early work showed high ambition and daring, and it pioneered

  8. Distribution and abundance of the polychaete, Manayunkia speciosa Leidy, in western Lake Erie

    USGS Publications Warehouse

    Hiltunen, Jarl K.

    1965-01-01

    The abundance and distribution of the freshwater polychaete, Manayunkia speciosa, in 1961, are described for western Lake Erie. Previous records reveal that the species has either been generally overlooked or presently its numbers have greatly increased in the area considered.

  9. Unravelling the genetic differentiation among varieties of the Neotropical savanna tree Hancornia speciosa Gomes.

    PubMed

    Collevatti, Rosane G; Rodrigues, Eduardo E; Vitorino, Luciana C; Lima-Ribeiro, Matheus S; Chaves, Lázaro J; Telles, Mariana P C

    2018-04-20

    Spatial distribution of species genetic diversity is often driven by geographical distance (isolation by distance) or environmental conditions (isolation by environment), especially under climate change scenarios such as Quaternary glaciations. Here, we used coalescent analyses coupled with ecological niche modelling (ENM), spatially explicit quantile regression analyses and the multiple matrix regression with randomization (MMRR) approach to unravel the patterns of genetic differentiation in the widely distributed Neotropical savanna tree, Hancornia speciosa (Apocynaceae). Due to its high morphological differentiation, the species was originally classified into six botanical varieties by Monachino, and has recently been recognized as only two varieties by Flora do Brasil 2020. Thus, H. speciosa is a good biological model for learning about evolution of phenotypic plasticity under genetic and ecological effects, and predicting their responses to changing environmental conditions. We sampled 28 populations (777 individuals) of Monachino's four varieties of H. speciosa and used seven microsatellite loci to genotype them. Bayesian clustering showed five distinct genetic groups (K = 5) with high admixture among Monachino's varieties, mainly among populations in the central area of the species geographical range. Genetic differentiation among Monachino's varieties was lower than the genetic differentiation among populations within varieties, with higher within-population inbreeding. A high historical connectivity among populations of the central Cerrado shown by coalescent analyses may explain the high admixture among varieties. In addition, areas of higher climatic suitability also presented higher genetic diversity in such a way that the wide historical refugium across central Brazil might have promoted the long-term connectivity among populations. Yet, FST was significantly related to geographic distances, but not to environmental distances, and coalescent analyses

  10. The Impeachment of Andrew Johnson. Web Lesson.

    ERIC Educational Resources Information Center

    Constitutional Rights Foundation, Los Angeles, CA.

    This lesson presents the historical background of Abraham Lincoln's selection of Andrew Johnson as his running mate in the election of 1864. The lesson considers the climate in the U.S. Congress after President Lincoln's assassination. The details of the impeachment and trial of President Andrew Johnson are given. The lesson presents three…

  11. Freshwater polychaetes (Manayunkia speciosa) near the Detroit River, western Lake Erie: Abundance and life‐history characteristics

    USGS Publications Warehouse

    Schloesser, Donald W.; Malakauskas, David M.; Malakauskas, Sarah J.

    2016-01-01

    Freshwater polychaetes are relatively rare and little-studied members of the benthos of lakes and rivers. We studied one polychaete species (Manayunkia speciosa) in Lake Erie near the mouth of the Detroit River. Abundances at one site were determined between 1961 and 2013 and life‐history characteristics at two sites were determined seasonally (March–November) in 2009–2010 and 2012–2013. Life‐history characteristics included abundances, length‐frequency distributions, presence/absence of constructed tubes, sexual maturity, and number and maturation of young of year (YOY) in tubes. Long-term abundances decreased in successive time periods between 1961 and 2003 (mean range = 57,570 to 2583/m2) but few changes occurred between 2003 and 2013 (mean = 5007/m2; range/y = 2355–8216/m2). Seasonal abundances varied substantially between sites and years, but overall, abundances were low in March–April, high in May–August, and low in September–November. Although reproduction was continuous throughout warmer months, en masse recruitment, as revealed by length–frequency distributions, occurred in a brief period late‐June to mid-July, and possibly in early-September. All life history characteristics, including tube construction, were dependent on water temperatures (> 5 °C in spring and < 15 °C in fall). These results generally agree with and complement laboratory studies of M. speciosa in the Pacific Northwest where M. speciosa hosts parasites that cause substantial fish mortalities. Although abundance ofM. speciosa near the mouth of the Detroit River was 33-fold lower in 2013 than it was in 1961, this population has persisted for five decades and, therefore, has the potential to harbor parasites that may cause fish mortalities in the Great Lakes.

  12. Hypaphorine, an indole alkaloid from Erythrina velutina, induced sleep on normal mice.

    PubMed

    Ozawa, Masaaki; Honda, Kazuki; Nakai, Izumi; Kishida, Akio; Ohsaki, Ayumi

    2008-07-15

    An indole alkaloid (hypaphorine (1)) was isolated from Brazilian medicinal plant, Erythrina velutina (Leguminosae). This compound was investigated for sleep promoting effects in mice, and the results showed that it significantly increased non-rapid eye movement (NREM) sleep time during the first hour after its administration. The NREM sleep time was enhanced by 33% in the experimental mice when compared to that of the controls. This study therefore confirmed its sleep promoting property.

  13. Ribosomal DNA identification of Nosema/Vairimorpha in freshwater polychaete, Manayunkia speciosa, from Oregon/California and the Laurentian Great Lakes

    USGS Publications Warehouse

    Malakauskas, David M.; Altman, Emory C.; Malakauskas, Sarah J.; Thiem, Suzanne M.; Schloesser, Donald W.

    2015-01-01

    We examined Manayunkia speciosa individuals from the Klamath River, Oregon/California and Lake Erie, Michigan, USA for the presence of Microsporidia. We identified microsporidian spores and sequenced their SSU, ITS, and part of the LSU rDNA. Phylogenetic analysis of SSU rDNA indicated spores from both populations belonged to the Nosema/Vairimorpha clade. PCR showed an infection prevalence in Lake Erie M. speciosa of 0.6% (95% CI = 0.5%, 0.7%). This represents the first known example of molecularly characterized Nosema/Vairimorpha isolates infecting a non-arthropod host.

  14. Andrew integrated reservoir description

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Todd, S.P.

    1996-12-31

    The Andrew field is an oil and gas accumulation in Palaeocene deep marine sands in the Central North Sea. It is currently being developed with mainly horizontal oil producers. Because of the field`s relatively small reserves (mean 118 mmbbls), the performance of each of the 10 or so horizontal wells is highly important. Reservoir description work at sanction time concentrated on supporting the case that the field could be developed commercially with the minimum number of wells. The present Integrated Reservoir Description (IRD) is focussed on delivering the next level of detail that will impact the understanding of the localmore » reservoir architecture and dynamic performance of each well. Highlights of Andrew IRD Include: (1) Use of a Reservoir Uncertainty Statement (RUS) developed at sanction time to focus the descriptive effort of both asset, support and contract petrotechnical staff, (2) High resolution biostratigraphic correlation to support confident zonation of the reservoir, (3) Detailed sedimentological analysis of the core including the use of dipmeter to interpret channel/sheet architecture to provide new insights into reservoir heterogeneity; (4) Integrated petrographical and petrophysical investigation of the controls on Sw-Height and relative permeability of water; (5) Fluids description using oil geochemistry and Residual Salt Analysis Sr isotope studies. Andrew IRD has highlighted several important risks to well performance, including the influence of more heterolithic intervals on gas breakthrough and the controls on water coning exerted by suppressed water relative permeability in the transition zone.« less

  15. Andrew integrated reservoir description

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Todd, S.P.

    1996-01-01

    The Andrew field is an oil and gas accumulation in Palaeocene deep marine sands in the Central North Sea. It is currently being developed with mainly horizontal oil producers. Because of the field's relatively small reserves (mean 118 mmbbls), the performance of each of the 10 or so horizontal wells is highly important. Reservoir description work at sanction time concentrated on supporting the case that the field could be developed commercially with the minimum number of wells. The present Integrated Reservoir Description (IRD) is focussed on delivering the next level of detail that will impact the understanding of the localmore » reservoir architecture and dynamic performance of each well. Highlights of Andrew IRD Include: (1) Use of a Reservoir Uncertainty Statement (RUS) developed at sanction time to focus the descriptive effort of both asset, support and contract petrotechnical staff, (2) High resolution biostratigraphic correlation to support confident zonation of the reservoir, (3) Detailed sedimentological analysis of the core including the use of dipmeter to interpret channel/sheet architecture to provide new insights into reservoir heterogeneity; (4) Integrated petrographical and petrophysical investigation of the controls on Sw-Height and relative permeability of water; (5) Fluids description using oil geochemistry and Residual Salt Analysis Sr isotope studies. Andrew IRD has highlighted several important risks to well performance, including the influence of more heterolithic intervals on gas breakthrough and the controls on water coning exerted by suppressed water relative permeability in the transition zone.« less

  16. Polyphenolic profile and bioactivity study of Oenothera speciosa Nutt. aerial parts.

    PubMed

    Marzouk, Mohamed S; Moharram, Fatma A; El Dib, Rabab A; El-Shenawy, Siham M; Tawfike, Ahmed F

    2009-04-07

    Two new flavonol glycosides, myricetin 4'-O-alpha-L-rhamnopyranoside (1) and quercetin 3'-O-alpha-L-rhamnopyranoside (2), together with a novel biflavonol compound, speciin (3), as well as eleven phenolic metabolites, namely myricitrin (4), europetin 3-O-alpha-L-(1)C(4)-rhamnopyranoside (5), quercitrin (6), hyperin (7), rhamnetin 3-O-beta-galacto-pyranoside (8), caffeic acid (9), caffeic acid methyl ester (10), chlorogenic acid (11), chlorogenic acid methyl ester (12), gallic acid (13) and gallic acid methyl ester (14), were identified from the 80 % methanol extract of the aerial parts (leaves and stems) of Oenothera speciosa Nutt. (Onagraceae). In addition myricetin (15), quercetin (16) and ellagic acid (17) were identified from the chloroform extract. The structures were established depending on their chemical and physical analyses (UV, HR-ESIMS, 1D and 2D NMR). It was found that 80 % aqueous methanol extract of O. speciosa is non-toxic to mice up to 5 g kg(-1)b wt. The investigated extract exhibited significant antihyperglycaemic and anti-inflammatory activities in a dose dependant manner. Also, the 80 % methanol extract, myricitrin(4) and hyperin(7) showed potent antioxidant activity in vitro using 1,1-diphenyl 2-picryl hydrazyl (DPPH) radical assay.

  17. Anti-inflammatory activity of aqueous extract and bioactive compounds identified from the fruits of Hancornia speciosa Gomes (Apocynaceae).

    PubMed

    Torres-Rêgo, Manoela; Furtado, Allanny Alves; Bitencourt, Mariana Angélica Oliveira; Lima, Maira Conceição Jerônimo de Souza; Andrade, Rafael Caetano Lisbôa Castro de; Azevedo, Eduardo Pereira de; Soares, Thaciane da Cunha; Tomaz, José Carlos; Lopes, Norberto Peporine; da Silva-Júnior, Arnóbio Antônio; Zucolotto, Silvana Maria; Fernandes-Pedrosa, Matheus de Freitas

    2016-08-05

    Hancornia speciosa Gomes (Apocynaceae), popularly known as "mangabeira," has been used in folk medicine to treat inflammatory disorders, hypertension, dermatitis, diabetes, liver diseases and gastric disorders. Although the ethnobotany indicates that its fruits can be used for the treatment of ulcers and inflammatory disorders, only few studies have been conducted to prove such biological activities. This study investigated the anti-inflammatory properties of the aqueous extract of the fruits of H. speciosa Gomes as well as its bioactive compounds using in vivo experimental models. The bioactive compounds were identified by High Performance Liquid Chromatography coupled with diode array detector (HPLC-DAD) and Liquid Chromatography coupled with Mass Spectrometry (LC-MS). The anti-inflammatory properties were investigated through in vivo tests, which comprised xylene-induced ear edema, carrageenan-induced peritonitis and zymosan-induced air pouch. The levels of IL-1β, IL-6, IL-12 and TNF-α were determined using ELISA. Rutin and chlorogenic acid were identified in the extract as the main secondary metabolites. In addition, the extract as well as rutin and chlorogenic acid significantly inhibited the xilol-induced ear edema and also reduced the cell migration in both carrageenan-induced peritonitis and zymosan-induced air pouch models. Reduced levels of cytokines were also observed. This is the first study that demonstrated the anti-inflammatory activity of the extract of H. speciosa fruits against different inflammatory agents in animal models, suggesting that its bioactive molecules, especially rutin and chlorogenic acid are, at least in part, responsible for such activity. These findings support the widespread use of Hancornia speciosa in popular medicine and demonstrate that its aqueous extract has therapeutical potential for the development of herbal drugs with anti-inflammatory properties.

  18. Analysis of lipid profile and atherogenic index in hyperlipidemic rat (Rattus norvegicus Berkenhout, 1769) that given the methanolic extract of Parijoto (Medinilla speciosa)

    NASA Astrophysics Data System (ADS)

    Sa'adah, Noor Nailis; Purwani, Kristanti Indah; Nurhayati, Awik Puji Dyah; Ashuri, Nova Maulidina

    2017-06-01

    Diet of high lipids cause hyperlipidemia, which marked by an increase of total cholesterols, triglycerides, LDL-C, and decreasing of HDL-C. Hyperlipidemia lead the occurrence of atherosclerosis, one of factors that trigger cardiovascular disease, as hypertention; coronary heart and stroke. Parijoto (M. speciosa) is endemic plants in Asia with a distribution center in Malaysia, Indonesia and Philippines. Parijoto contain phytochemical components such as flavonoids, saponins and kardenolin. Flavonoid potensial as an antioxidants and can improve the hyperlipidemia condition. This study was aimed to determine lipid profiles and atherogenic index of hyperlipidemic Wistar rats (R. norvegicus Berkenhout, 1769) which given the methanolic extract of Parijoto (M. speciosa). The research was done with pre and post test randomized control group design. Rats were given a mixture of duck yolk and reused cooking oil (1:1) orally as much as 1% of body weight (BW) for 30 days. After hyperlipidemia achieved, rats were divided into 5 group: normal rats, hyperlipidemic rats, hyperlipidemic rats were given the methanolic extract of Parijoto (M. speciosa) 500 mg/kg, 1000 mg/kg, and 1500 mg/kg BW. Blood samples were collected when rats in hyperlipidemia conditions and after treatment with the methanolic extract of Parijoto (M. speciosa) for 30 days. The data of total cholesterol, HDL-Cholesterol, LDL-Cholesterol level, and atherogenic index were analyzed using ANOVA followed by Tukey test at 5% significance level. The result showed that giving of methanolic extract of Parijoto (M. speciosa) in hyperlipidemic rats reduced the total cholesterol, LDL-Cholesterol levels, and increased of HDL-cholesterol levels significantly (p<0.01), so atherogenic index reduced significantly too (p<0.01). Total cholesterol and LDL-Cholesterol levels were positively correlated with the atherogenic index, whereas HDL-cholesterol levels were negatively correlated with the atherogenic index.

  19. Interview with Deborah Andrews

    ERIC Educational Resources Information Center

    Ryan, Cynthia

    2005-01-01

    This article presents an interview with Deborah Andrews about her experiences during her editorship of "Business Communication Quarterly." From June 1997 to March 2005, Debby served as editor of the journal, encouraging all readers to ask important questions about their work: How should we define business communication? On which disciplines and…

  20. The human side of Hurricane Andrew

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Marshall, R.; Callander, R.C.

    1994-12-31

    This paper examines the long-term psychological effects of the nation`s worst natural disaster on the employees of the Turkey Point nuclear power plant. It also examines the efforts made by plant personnel and company volunteers to aid employees` families affected by the storm. Despite significant damage at the plant, unit 4 was returned to service 5 weeks after the August 24, 1992, hurricane. Unit 3 was returned to service on December 3, 1992. Unit 3 was originally scheduled to start a refueling outage the day Hurricane Andrew struck. While plant personnel are still recovering from Andrew`s impact, the plant`s performancemore » has never been better. On May 26, 1993, the plant completed a record-breaking 46-day refueling outage - 7 days ahead of schedule and $3 million under budget. Turkey Point`s recovery, return to service, and superior performance would not have been possible without the efforts of hundreds of employees who put their personal tragedies aside and focused on the common goal of the plant`s operation. To help employees with rebuilding their lives, the plant launched extensive assistance programs. Although the plant returned to normal operation, plant personnel continue to struggle in a community whose infrastructure (homes, schools, stores, etc.) have been almost eliminated.« less

  1. Cell shape can be uncoupled from formononetin induction in a novel cell line from Callerya speciosa.

    PubMed

    Qiao, Fei; Jiang, Xue-Fei; Cong, Han-Qing; Sun, Hua-Peng; Li, Li; Nick, Peter

    2018-04-01

    It is the first time that formononetin produced by cell culture and its accumulation was shown to be triggered by specific stress signalling linked jasmonate pathway. Callerya speciosa, an endangered traditional Chinese medicine plant, is intensively used in traditional folk medicine. To develop sustainable alternatives for the overexploitation of natural resources, a suspension cell line was created from C. speciosa. Ingredients of C. speciosa, for instance the isoflavone formononetin, are formed during a peculiar swelling response of the root, which is considered as a quality trait for commercial application. A cell strain with elongated cells was obtained by using synthetic cytokinin 6-benzylaminopurine (6-BA) and synthetic auxin picloram. Both, picloram and 6-BA, promote cell division, whereas picloram was shown to be crucial for the maintenance of axial cell expansion. We addressed the question, whether the loss of axiality observed in the maturating root is necessary and sufficient for the accumulation of formononetin. While we were able to mimic a loss of axiality for cell expansion, either by specific combinations of 6-BA and picloram, or by treatment with the anti-microtubular compound oryzalin, formononetin was not detectable. However, formononetin could be induced by the stress hormone methyl jasmonate (MeJA), as well as by the bacterial elicitor flagellin peptide (flg22), but not by a necrosis inducing protein. Combined the fact that none of these treatments induced the loss of axiality, we conclude that formononetin accumulates in response to basal defence and unrelated with cell swelling.

  2. Andrew W. S. In

    ERIC Educational Resources Information Center

    Nishimoto, Warren

    2007-01-01

    This article presents an interview with Andrew W. S. In, professor and dean in the University of Hawai'i's College of Education from 1951 to 1984. Born and raised in Honolulu, In attended Royal Elementary, Central Junior High, and McKinley High schools, graduating from McKinley in 1938. He then attended the University of Hawai'i Teachers College…

  3. The Americas and Hurricane Andrew

    NASA Technical Reports Server (NTRS)

    1992-01-01

    Image taken on August 25, 1992 by NOAA GOES-7 of the Americas and Hurricane Andrew.

    Photo Credit: Image produced by F. Hasler, M. Jentoft-Nilsen, H. Pierce, K. Palaniappan, and M. Manyin. NASA Goddard Lab for Atmospheres - Data from National Oceanic and Atmospheric Administration (NOAA).

  4. 75 FR 32221 - Whirlpool Corporation, Evansville Division, Including On-Site Leased Workers from Andrews...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-07

    ..., Evansville Division, Including On-Site Leased Workers from Andrews International, Inc., Evansville, IN... that workers leased from Andrews International, Inc. were employed on-site at the Evansville, Indiana... findings, the Department is amending this certification to include leased workers from Andrews...

  5. Generating an Empirical Probability Distribution for the Andrews-Pregibon Statistic.

    ERIC Educational Resources Information Center

    Jarrell, Michele G.

    A probability distribution was developed for the Andrews-Pregibon (AP) statistic. The statistic, developed by D. F. Andrews and D. Pregibon (1978), identifies multivariate outliers. It is a ratio of the determinant of the data matrix with an observation deleted to the determinant of the entire data matrix. Although the AP statistic has been used…

  6. A Concise Synthesis of the Erythrina Alkaloid 3–Demethoxyerythratidinone via Combined Rhodium Catalysis

    PubMed Central

    Joo, Jung Min; David, Ramoncito A.; Yuan, Yu; Lee, Chulbom

    2010-01-01

    The total synthesis of the erythrina alkaloid 3–demethoxyerythratidinone has been achieved via a strategy based on combined rhodium catalysis. The catalytic tandem cyclization effected by the interplay of alkynyl and vinylidene rhodium species allows for efficient access to the A and B rings of the tetracyclic erythrinane skeleton in a single step. The synthesis also features rapid preparation of the requisite precursor for the double ring closure and thus has been completed in only 7 total steps in 41% overall yield. PMID:21090648

  7. In vitro chronotropic effects of Erythrina senegalensis DC (Fabaceae) aqueous extract on mouse heart slice and pluripotent stem cell-derived cardiomyocytes.

    PubMed

    Nembo, Erastus Nembu; Atsamo, Albert Donatien; Nguelefack, Télesphore Benoît; Kamanyi, Albert; Hescheler, Jürgen; Nguemo, Filomain

    2015-05-13

    Erythrina senegalensis DC (Fabaceae) bark is commonly used in sub-Saharan traditional medicine for the treatment of many diseases including gastrointestinal disorders and cardiovascular diseases. In this study, we investigated the effect of the aqueous extract of the stem bark of Erythrina senegalensis on the contractile properties of mouse ventricular slices and human induced pluripotent stem (hiPS) cell-derived cardiomyocytes. We also investigated the cytotoxic effect of the extract on mouse embryonic stem (ES) cells differentiating into cardiomyocytes (CMs). We used well-established electrophysiological technologies to assess the effect of Erythrina senegalensis aqueous extract (ESAE) on the beating activity of mouse ventricular slices, mouse ES and hiPS cell-derived CMs. To study the cytotoxic effect of our extract, differentiating mouse ES cells were exposed to different concentrations of ESAE. EB morphology was assessed by microscopy at different stages of differentiation whereas cell viability was measured by flow cytometry, fluorometry and immunocytochemistry. The electrical activity of CMs and heart slices were respectively captured by the patch clamp technique and microelectrode array (MEA) method following ESAE acute exposure. Our findings revealed that ESAE exhibits a biphasic chronotropic activity on mouse ventricular slices with an initial low dose (0.001 and 0.01 µg/mL) decrease in beating activity followed by a corresponding significant increase in chronotropic activity at higher doses above 10 µg/mL. The muscarinic receptor blocker, atropine abolished the negative chronotropic activity of ESAE, while propranolol successfully blocked its positive chronotropic activity. ESAE showed a significant dose-dependent positive chronotropic activity on hiPS cell-derived CMs. Also, though not significantly, ESAE decreased cell viability and increased total caspase-3/7 activity of mouse ES cells in a concentration-dependent manner. Erythrina senegalensis

  8. Flavones from Erythrina falcata are modulators of fear memory.

    PubMed

    de Oliveira, Daniela Rodrigues; Zamberlam, Cláudia R; Gaiardo, Renan Barreta; Rêgo, Gizelda Maia; Cerutti, Janete M; Cavalheiro, Alberto J; Cerutti, Suzete M

    2014-08-05

    Flavonoids, which have been identified in a variety of plants, have been demonstrated to elicit beneficial effects on memory. Some studies have reported that flavonoids derived from Erythrina plants can provide such beneficial effects on memory. The aim of this study was to identify the flavonoids present in the stem bark crude extract of Erythrina falcata (CE) and to perform a bioactivity-guided study on conditioned fear memory. The secondary metabolites of CE were identified by high performance liquid chromatography combined with a diode array detector, electrospray ionization tandem mass spectrometry (HPLC-DAD-ESI/MSn) and nuclear magnetic resonance (NMR). The buthanolic fraction (BuF) was obtained by partitioning. Subfractions from BuF (BuF1 - BuF6) and fraction flavonoidic (FfA and FfB) were obtained by flash chromatography. The BuF3 and BuF4 fractions were used for the isolation of flavonoids, which was performed using HPLC-PAD. The isolated substances were quantified by HPLC-DAD and their structures were confirmed by nuclear magnetic resonance (NMR). The activities of CE and the subfractions were monitored using a one-trial, step-down inhibitory avoidance (IA) task to identify the effects of these substances on the acquisition and extinction of conditioned fear in rats. Six subclasses of flavonoids were identified for the first time in CE. According to our behavioral data, CE, BuF, BuF3 and BuF4, the flavonoidic fractions, vitexin, isovitexin and 6-C-glycoside-diosmetin improved the acquisition of fear memory. Rats treated with BuF, BuF3 and BuF4 were particularly resistant to extinction. Nevertheless, rats treated with FfA and FfB, vitexin, isovitexin and 6-C-glycoside-diosmetin exhibited gradual reduction in conditioned fear response during the extinction retest session, which was measured at 48 to 480 h after conditioning. Our results demonstrate that vitexin, isovitexin and diosmetin-6-C-glucoside and flavonoidic fractions resulted in a significant

  9. [Preliminary Investigation of the Amount, the Molecular Weight and the Activity of Polysaccharides from Chaenomeles Speciosa Fruits in Ethanol Fractional Precipitation].

    PubMed

    Tian, Bing-mei; Xie, Xiao-mei; Shen, Pan-pan; Yang, Mo; Zhang, Sheng-long; Tang, Qing-jiu

    2015-05-01

    Chaenomeles speciosa fruits were extracted using water. The extracts were precipitated with 20%~95% (φ) ethanol, respectively. The amount of total polysaccharide was measured with phenol-sulfuric acid method. A method using high-performance size-exclusion chromatography (HPSEC) equipped with multiangle laser-light-scattering photometry (MALLS) and differential refractometry (RI) was presented for determining the molecular weight and molecular weigh distribution. RAW264.7 macrophage were cultured and stimulated with the polysaccharides in vitro and the production of nitric oxide in the cells was determined by the Griess assay. The aim of the study is to determine the amount and the molecular weight of the polysaccharides from Chaenomeles speciosa fruits, and preliminary investigate the immunomodulatory activity, The study provided the basis datas for the further research of Chaenomeles speciosa fruits. , and provided a simple and system method for the research of natural polysaccharide. The ethanol fractional precipitation showed that the order of total polysaccharide content was 95%>80%>40% ≥60%>20%. The results indicated that most polysaccharide from Chaenomeles speciosa fruits might be precipitated when ethanol concentration was up to 95% (T) and the crude polysaccharide purity had risen from 35. 1% to 45. 0% when the concentration of ethanol increased from 20% to 95%. HPSEC-MALLS-RI system showed that all the polysaccharide samples had the similar compositions. They appeared three chromatographic peaks and the retention time were not apparently different. The Mw were 6. 570 X 10(4) g . mol-1 and 1. 393 X 10(4) g . mol-1 respectively, and one less than 10 000 which was failure to obtain accurate values. The molecular weight of the first two polysaccharide distribution index(Mw/Mn)were 1. 336 and 1. 639 respectively. The polysaccharide samples had not exhibited immunomodulatory activity assessed on the basis of nitric oxide production by RAW264. 7 macrophage

  10. Amino acid concentrations in the nectars of Southern African bird-pollinated flowers, especially aloe and erythrina.

    PubMed

    Nicolson, Susan W

    2007-09-01

    Amino acids in nectar have received less attention than the more abundant sugars. The dilute nectars of 32 species of southern African plants that are pollinated by passerine birds were analyzed by HPLC, and the effect of pollen contamination and the variation among inflorescences and plants were also examined. Aloe marlothii and some Erythrina species were found to have high total amino acid concentrations, sometimes exceeding 100 mM. Other Aloe species, as well as Greyia, Strelitzia, Schotia, Cotyledon, and Melianthus, had low nectar amino acid concentrations. Total amino acid concentrations varied much more than the sugar concentrations of these nectars as measured with a refractometer. Pollen contamination, previously claimed to be a major source of error in the measurement of nectar amino acids, had no effect on amino acids in the nectar of A. marlothii. Variation among inflorescences of Erythrina lysistemon was greater than that among trees, and most of the variation was because of relatively abundant nonessential amino acids such as asparagine and glutamine. High amino acid concentrations, especially in 'dilute' nectars, represent a substantial contribution of nonsugar solutes to 'sugar' concentrations measured with a refractometer. Amino acids in nectar may contribute to the nitrogen requirements of bird pollinators.

  11. A History of the Andrew File System

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bashear, Derrick

    2011-02-22

    Derrick Brashear and Jeffrey Altman will present a technical history of the evolution of Andrew File System starting with the early days of the Andrew Project at Carnegie Mellon through the commercialization by Transarc Corporation and IBM and a decade of OpenAFS. The talk will be technical with a focus on the various decisions and implementation trade-offs that were made over the course of AFS versions 1 through 4, the development of the Distributed Computing Environment Distributed File System (DCE DFS), and the course of the OpenAFS development community. The speakers will also discuss the various AFS branches developed atmore » the University of Michigan, Massachusetts Institute of Technology and Carnegie Mellon University.« less

  12. The McAndrews Leadership Lecture: February 2016, by Dr Greg Kawchuk. Putting the "Act" Back in Chiropractic.

    PubMed

    Kawchuk, Gregory Neil

    2017-12-01

    The McAndrews Leadership Lecture was developed by the American Chiropractic Association to honor the legacy of Jerome F. McAndrews, DC, and George P. McAndrews, JD, and their contributions to the chiropractic profession. This article is an edited and truncated version of the McAndrews Leadership Lecture given by Dr Greg Kawchuk on February 27, 2016, in Washington, DC, at the National Chiropractic Leadership Conference. This was the second McAndrews lecture in this annual series.

  13. Personal profile: interview with Bill Andrews, Ph.D.

    PubMed

    Andrews, Bill

    2011-08-01

    Dr. William H. Andrews has worked in the biotech industry for 31 years, focusing the last 19 years on finding ways to extend human life span through the intervention of telomere shortening in human cells. Dr. Andrews earned his Ph.D. in Molecular and Population Genetics at the University of Georgia. He was a Senior Scientist at Armos Corporation and Codon Corporation, Director of Molecular Biology at Codon and at Geron Corporation, and Director of Technology Development at EOS Biosciences. He is presently the founder, President, and CEO of Sierra Sciences, a biotechnology company focused exclusively on finding drugs that will transiently induce the expression of endogenous telomerase in human cells. Sierra Sciences has already identified more than 30 such drugs and is presently characterizing their mechanism of action. While Director of Molecular Biology at Geron Corporation, Dr. Andrews was one of the principal discoverers of both the RNA and protein components of human telomerase and was awarded second place as "National Inventor of the Year" in 1997 for this work. He is presently a named inventor on 43 U.S- issued telomerase patents.

  14. Libraries and Andrew Carnegie's Challenge.

    ERIC Educational Resources Information Center

    Gregorian, Vartan

    This essay by the president of the Carnegie Corporation of New York (reprinted from the 1998 annual report) opens by noting that the year 1999 marks the 100th anniversary of Andrew Carnegie's support for the planning and development of 65 branch libraries of the New York Public Library System, a gift that came to more than $5.2 million. Discussion…

  15. Designer BHAs reduce costs on Andrew/Cyrus

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Klein, R.; Todd, S.; Clark, G.

    1997-10-01

    A key mechanism to development of Andrew/Cyrus has been the development of alliances between BP Exploration, its field partners and various contractors. One such joint venture was the well engineering alliance between BP, Schlumberger, Baker Hughes INTEQ and Transocean, created to deliver five predrilled horizontal wells in the two fields prior to Andrew platform installation. This alliance provided the opportunity to radically change usual ways of doing business in the well engineering arena. One specific aspect involved a rigorous learning process within the team. Rapid learning before and during the operation led to several substantial improvements, one of which wasmore » the development of designer bottomhole assembly (BHA) configurations. Continual development of these assemblies has optimized well placement, bringing enhanced value while reducing costs and increasing potential alliance gainshare.« less

  16. The Physics of Beams: The Andrew Sessler Symposium

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Barletta, W.A.

    1996-03-01

    These proceedings represent papers presented at the Andrew Sessler Symposium held at the Lawrence Berkeley National Laboratory in honor of Andrew Sessler{close_quote}s over forty years of major scientific contributions to accelerator and beam physics as well as in celebration of his 65th birthday. The symposium was sponsored by the United States Department of Energy. The topics discussed include linear colliders, past history and future speculations, ELOISATRON at 100 TeV beam, manipulating charged particle beams by means of plasma and collective instabilities in accelerator and storage rings. There were 10 papers presented and 8 have been abstracted for the Energy Sciencemore » and Technology database.(AIP)« less

  17. Growth, chemical composition and soil properties of Tipuana speciosa (Benth.) Kuntze seedlings irrigated with sewage effluent

    NASA Astrophysics Data System (ADS)

    Ali, Hayssam M.; Khamis, Mohamed H.; Hassan, Fatma A.

    2012-06-01

    This study was carried out at a greenhouse of Sabahia Horticulture Research Station, Alexandria, Egypt, to study the effect of sewage effluent on the growth and chemical composition of Tipuana speciosa (Benth.) Kuntze seedlings as well as on soil properties for three stages. The irrigation treatments were primary-treated wastewater and secondary-treated wastewater, in addition to tap water as control. Therefore, the treated wastewater was taken from oxidation ponds of New Borg El-Arab City. Results of these study revealed that the primary effluent treatment explored the highest significant values for vegetative growth and biomass, compared to the other treatments. In addition, the higher significant concentration and uptake of chemical composition in different plant parts were obtained from the primary effluent treatment during the three stages of irrigation. It was found that the concentration of heavy metals in either plant or soil was below as compared to the world-recommended levels. These findings suggested that the use of sewage effluent in irrigating T. speciosa seedlings grown in calcareous soil was beneficial for the improvement of soil properties and production of timber trees, and also important for the safe manner of disposal of wastewater.

  18. Physical habitat predictors of Manayunkia speciosa distribution in the Klamath River and implications for management of Ceratomyxa shasta, a parasite with a complex life cycle

    NASA Astrophysics Data System (ADS)

    Jordan, M. S.; Alexander, J. D.; Grant, G. E.; Bartholomew, J. L.

    2011-12-01

    Management strategies for parasites with complex life cycles may target not the parasite itself, but one of the alternate hosts. One approach is to decrease habitat for the alternate host, and in river systems flow manipulations may be employed. Two-dimensional hydraulic models can be powerful tools for predicting the relationship between flow alterations and changes in physical habit, however they require a rigorous definition of physical habitat for the organism of interest. We present habitat characterization data for the case of the alternate host of a salmonid parasite and introduce how it will be used in conjunction with a 2-dimensional hydraulic model. Ceratomyxa shasta is a myxozoan parasite of salmonids that requires a freshwater polychaete Manayunkia speciosa to complete its life cycle. Manayunkia speciosa is a small (3mm) benthic filter-feeding worm that attaches itself perpendicularly to substrate through construction of a flexible tube. In the Klamath River, CA/OR, C. shasta causes significant juvenile salmon mortality, imposing social and economic losses on commercial, sport and tribal fisheries. An interest in manipulating habitat for the polychaete host to decrease the abundance of C. shasta has therefore developed. Unfortunately, there are limited data on the habitat requirements of M. speciosa or the influence of streamflow regime and hydraulics on population dynamics and infection prevalence. This work aims to address these data needs by identifying physical habitat variables that influence the distribution of M. speciosa and determining the relationship between those variables, M. speciosa population density, and C. shasta infection prevalence. Biological samples were collected from nine sites representing three river features (runs, pools, and eddies) within the Klamath River during the summer and fall of 2010 and 2011. Environmental data including depth, velocity, and substrate, were collected at each polychaete sampling location. We tested

  19. The Implementation of IAS 16 and IAS 41 at Andrew Peller Limited

    ERIC Educational Resources Information Center

    Lapointe-Antunes, Pascale; Moore, James

    2013-01-01

    This case asks students to play the role of Doug Grodeckie, Manager of Financial Reporting at Andrew Peller Limited (APL). Doug was asked to prepare a report analyzing Andrew Peller Limited's current tangible long-lived assets disclosures and making recommendations on how best to comply with International Accounting Standard (IAS) 16 Property,…

  20. First report of downy mildew disease caused by Plasmopara halstedii on the native Rudbeckia fulgida Aiton var. speciosa (Wender.)

    USDA-ARS?s Scientific Manuscript database

    The showy black-eyed Susan Rudbeckia fulgida Aiton var. speciosa (Wender.) is an important perennial wildflower native to the Northeast and Midwest regions of the United States. Besides its aesthetic value in the landscape, this native plant attracts pollinators and provides seeds for birds during t...

  1. THREE HIGH SCHOOLS REVISITED--ANDREWS, MCPHERSON, AND NOVA. PROFILES OF SIGNIFICANT SCHOOLS.

    ERIC Educational Resources Information Center

    KOHN, SHERWOOD D.

    THREE SCHOOLS--NOVA HIGH SCHOOL IN FORT LAUDERDALE, FLORIDA, MCPHERSON SENIOR HIGH SCHOOL IN MCPHERSON, KANSAS, AND ANDREWS SENIOR HIGH SCHOOL IN ANDREWS, TEXAS--ARE EXAMINED IN THIS REPORT. ALL OF THEM ARE CONSIDERED ADVANCED EDUCATIONAL PLANTS, AND ALL HAVE BEEN IN FULL OPERATION FOR LESS THAN FIVE YEARS, BUT MOST OF THEIR INNOVATIONAL ASPECTS…

  2. Carpet in Andrews High School. A Report by the Carpet Evaluation Team.

    ERIC Educational Resources Information Center

    Wallace, Morris S.; And Others

    In the spring of 1965, the Board of Trustees of Andrews Independent School District entered into a contract with the carpet evaluation team to analyze and evaluate the use of carpeting in the Andrews Public Schools, with emphasis on the senior high school. The two $5,000 grants served as the basis for paying for the expenses and professional…

  3. Dr. Andrew Foster: A Literature Review

    ERIC Educational Resources Information Center

    Runnels, Joel

    2017-01-01

    Often compared to Laurent Clerc, Thomas Gallaudet, and Alexander Graham Bell, Dr. Andrew Foster was a deaf African American who founded 32 schools for the deaf in 13 African nations. The 60th anniversary of his arrival in Liberia and Ghana and the 30th anniversary of his tragic death in a Rwanda airplane accident both occur in 2017. Renewed…

  4. Interview with 2018 Hooke medal winner Andrew McAinsh.

    PubMed

    2018-03-14

    Andrew McAinsh received his PhD from the University of Cambridge, UK, working in the laboratory of Steve Jackson on DNA damage and repair mechanisms in yeast. He then joined the laboratory of Peter Sorger as a Jane Coffin Childs Fellow to work as a post-doc on kinetochore biology at the Massachusetts Institute of Technology, Boston, USA. In 2005, he returned to the UK to establish his independent laboratory at the Marie Curie Research Institute, Surrey, before moving to the University of Warwick in 2009 to co-found the Centre for Mechanochemical Cell Biology (CMCB). Subsequently, Andrew was appointed Professor of Cell Biology and became a Wellcome Senior Investigator, and was awarded a Royal Society Wolfson Research Merit Award. He co-directs the MRC Doctoral Training Partnership in Interdisciplinary Biomedical Research, and in 2017 became Head of Division of Biomedical Sciences at Warwick Medical School. Andrew is interested in understanding how the chromosomal multi-protein complex, the kinetochore, ensures error-free chromosome segregation. He is the recipient of the 2018 Hooke medal, established to recognize an emerging leader in cell biology. The Hooke medal is awarded at the annual spring meeting of the British Society for Cell Biology (BSCB). © 2018. Published by The Company of Biologists Ltd.

  5. Three High Schools Revisited--Andrews, McPherson, and Nova. Profiles of Significant Schools.

    ERIC Educational Resources Information Center

    Kohn, Sherwood D.

    Three schools--Nova High School in Fort Lauderdale, Florida, McPherson Senior High School in McPherson, Kansas, and Andrews Senior High School in Andrews, Texas--are examined in this report. All of them are considered advanced educational plants, and all have been in full operation for less than five years, but most of their innovational aspects…

  6. Comparison of three chromatographic techniques for the detection of mitragynine and other indole and oxindole alkaloids in mitragyna speciosa (Kratom) plants

    USDA-ARS?s Scientific Manuscript database

    Leaves of the Southeast Asian plant Mitragyna speciosa (kratom) are used to suppress pain and mitigate opioid withdrawal syndromes. The potential threat of abuse and ready availability of this uncontrolled psychoactive plant material in the U.S. have led to the need for improved analytical technique...

  7. Responses to simulated nitrogen deposition by the neotropical epiphytic orchid Laelia speciosa

    PubMed Central

    Díaz-Álvarez, Edison A.; Lindig-Cisneros, Roberto

    2015-01-01

    Potential ecophysiological responses to nitrogen deposition, which is considered to be one of the leading causes for global biodiversity loss, were studied for the endangered endemic Mexican epiphytic orchid, Laelia speciosa, via a shadehouse dose-response experiment (doses were 2.5, 5, 10, 20, 40, and 80 kg N ha−1 yr−1) in order to assess the potential risk facing this orchid given impending scenarios of nitrogen deposition. Lower doses of nitrogen of up to 20 kg N ha yr−1, the dose that led to optimal plant performance, acted as fertilizer. For instance, the production of leaves and pseudobulbs were respectively 35% and 36% greater for plants receiving 20 kg N ha yr−1 than under any other dose. Also, the chlorophyll content and quantum yield peaked at 0.66 ± 0.03 g m−2 and 0.85 ± 0.01, respectively, for plants growing under the optimum dose. In contrast, toxic effects were observed at the higher doses of 40 and 80 kg N ha yr−1. The δ13C for leaves averaged −14.7 ± 0.2‰ regardless of the nitrogen dose. In turn, δ15N decreased as the nitrogen dose increased from 0.9 ± 0.1‰ under 2.5 kg N ha−1yr−1 to −3.1 ± 0.2‰ under 80 kg N ha−1yr−1, indicating that orchids preferentially assimilate NH4+ rather than NO3− of the solution under higher doses of nitrogen. Laelia speciosa showed a clear response to inputs of nitrogen, thus, increasing rates of atmospheric nitrogen deposition can pose an important threat for this species. PMID:26131375

  8. 9. HISTORIC AMERICAN BUILDINGS SURVEY L. D. ANDREW PHOTOGRAPHER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. HISTORIC AMERICAN BUILDINGS SURVEY L. D. ANDREW - PHOTOGRAPHER SEPT. 7, 1936 BEAM, CORNICE, AND CEILING ORNAMENT IN FRONT HALL - Sorrel-Weed House, 6 West Harris Street, Savannah, Chatham County, GA

  9. Research publications of the H.J. Andrews Experimental Forest, Cascade Range, Oregon: 1998 supplement.

    Treesearch

    Donald L. Henshaw; Sarah E. Greene; Tami Lowry

    1998-01-01

    This bibliography updates the list of publications, abstracts, theses, and unpublished reports included in "Research Publications of the H.J. Andrews Experimental Forest, Cascade Range, Oregon, 1948 to 1986" (General Technical Report PNW-GTR-201) and "Research Publications of the H.J. Andrews Experimental Forest, Cascade Range, Oregon: 1988 Supplement...

  10. Protective effects of Lagerstroemia speciosa on 3-morpholinosydnonimine (SIN-1)-induced oxidative stress in HIT-T15 pancreatic β cells.

    PubMed

    Song, Jia-Le; Zhao, Xin; Wang, Qiang; Zhang, Ting

    2013-05-01

    Reactive oxygen species (ROS)-induced pancreatic β cell death affects insulin secretion and is important in the pathogenesis of diabetes. Lagerstroemia speciosa, a traditional folk medicine, has been used for t he prevention and treatment of diabetes. However, whether Lagerstroemia speciosa has a cytoprotective effect on pancreatic β cells remains to be elucidated. The present study aimed to investigate the cytoprotective effects of hot water extracts from Lagerstroemia speciosa leaves (LWE) on 3-morpholinosydnonimine (SIN-1)-induced oxidative damage in Syrian hamster pancreatic insulinoma HIT-T15 cells. The HIT-T15 cells were first treated with SIN-1 (50 µM) for 24 h and then co-incubated with LWE for 48 h. SIN-1 significantly decreased HIT-T15 cell viability (P<0.05); however, LWE did not exert a significant cytotoxic effect and increased the viability of HIT-T15 cells in a dose‑dependent manner. To further investigate the protective effects of LWE on SIN-1‑induced oxidative stress in HIT-T15 cells, the cellular levels of ROS, lipid peroxidation and endogenous antioxidant enzymes, including superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GSH-px), were determined. LWE decreased the intracellular levels of ROS and lipid peroxidation, and increased the activities of antioxidant enzymes. These results suggest that LWE has a cytoprotective effect against SIN-1‑induced oxidative stress in HIT-T15 cells through the inhibition of lipid peroxidation, a decrease in ROS levels and an increase in antioxidant enzyme activity. In addition, LWE increased insulin secretion in SIN-1-treated HIT-T15 cells. Our results suggested that LWE were effective in the treatment of diabetes. Further studies are required to study the anti-diabetic molecular mechanism in a cell model.

  11. Effects of the Aqueous Extract of Eremomastax speciosa (Acanthaceae) on Sexual Behavior in Normal Male Rats.

    PubMed

    Nchegang, B; Mezui, C; Longo, F; Nkwengoua, Z E; Amang, A P; Tan, P V

    2016-01-01

    Objective. We studied prosexual effects of Eremomastax speciosa aqueous extract in male adult rats. Materials and Methods. 100 and 500 mg/kg of extract were administered orally (days 0, 1, 4, 7, 14, and 28 (posttreatment)). The sexual behavior of rats receiving a single dose (500 mg/kg) was also evaluated after pretreatment with Lω-NAME (10 mg/kg), haloperidol (1 mg/kg), or atropine (5 mg/kg). Controls received distilled water or testosterone enanthate (20 mg/kg/day/3 days (s.c.) before the test). Results. The extract (days 1-14) had no significant effect on mount, intromission, and ejaculation frequencies but on day 28 (14 days after treatment), it increased frequency of mounts and intromissions at 500 mg/kg. Mount, intromission, and ejaculation latencies reduced and postejaculatory intervals decreased but the effect did not persist 2 weeks after treatment. Extract prosex effects were greatly reduced by atropine and completely abolished by haloperidol, while Lω-NAME increased mount latency and potentiated extract effect on intromission and ejaculation latencies. Conclusion. In summary, E. speciosa extract can have positive effects on male sexual motivation and performance when administered for two weeks at the dose of 500 mg/kg. The effects (dopaminergic and/or cholinergic dependent) tend to appear during the posttreatment period.

  12. Evaluation of Andrews' Analysis as a Predictor of Ideal Sagittal Maxillary Positioning in Orthognathic Surgery.

    PubMed

    Resnick, Cory M; Kim, Somi; Yorlets, Rachel R; Calabrese, Carly E; Peacock, Zachary S; Kaban, Leonard B

    2018-03-22

    There is no universally accepted method for determining the ideal sagittal position of the maxilla in orthognathic surgery. In "Element II" of "The Six Elements of Orofacial Harmony," Andrews used the forehead to define the goal maxillary position. The purpose of this study was to compare how well this analysis correlated with postoperative findings in patients who underwent bimaxillary orthognathic surgery planned using other guidelines. The authors hypothesized that the Andrews analysis would more consistently reflect clinical outcomes than standard angular and linear measurements. This is a retrospective cohort study of patients who had bimaxillary orthognathic surgery and achieved an acceptable esthetic outcome. Patients with no maxillary sagittal movement, obstructive sleep apnea, cleft or craniofacial diagnoses, or who were non-Caucasian were excluded. Treatment plans were developed using photographs, radiographs, and standard cephalometric measurements. The Andrews analysis, measuring the distance from the maxillary incisor to the goal anterior limit line, and standard measurements were applied to end-treatment records. The Andrews analysis was statistically compared with standard methods. There were 493 patients who had orthognathic surgery from 2007 through 2014, and 60 (62% women; mean age, 22.1 ± 6.8 yr) met the criteria for inclusion in this study. The mean Andrews distances were -4.8 ± 2.9 mm for women and -8.6 ± 4.6 mm for men preoperatively and -0.6 ± 2.1 mm for women and -1.9 ± 3.4 mm for men postoperatively. For women, the Andrews analysis was closer to the goal value (0 mm) postoperatively than any standard measurement (P < .001). For men, the linear distance from the A point to a vertical line tangent to the nasion from the McNamara analysis performed best (P < .001), followed by the Andrews analysis. The Andrews analysis correlated well with the final esthetic sagittal maxillary position in the present sample

  13. The MacAndrew Scale as a Measure of Substance Abuse and Delinquency among Adolescents.

    ERIC Educational Resources Information Center

    Rathus, Spencer A.; And Others

    1980-01-01

    Used regression equations to determine the predictive power of the abbreviated MacAndrew Scale of the MMPI-168 on self-reported delinquent behavior of 1,672 high school students. The abbreviated MacAndrew Scale score successfully predicted alcohol abuse but was also related to crimes against property and persons and to marijuana usage. (Author)

  14. Necessary work: discovering old forests, new outlooks, and community on the H.J. Andrews Experimental Forest, 1948-2000.

    Treesearch

    Max G. Geier

    2007-01-01

    The H.J. Andrews Experimental Forest (Andrews Forest) is both an idea and a particular place. It is an experimental landscape, a natural resource, and an ecosystem that has long inspired many people. On the landscape of the Andrews Forest, some of those people built the foundation for a collaborative community that fosters closer communication among the scientists and...

  15. Dormancy as exaptation to protect mimetic seeds against deterioration before dispersal

    PubMed Central

    Brancalion, Pedro H. S.; Novembre, Ana D. L. C.; Rodrigues, Ricardo R.; Marcos Filho, Júlio

    2010-01-01

    Background and Aims Mimetic seeds simulate the appearance of fleshy fruits and arilled seeds without producing nutritive tissues as a reward for seed dispersers. In this strategy of seed dispersal, seeds may remain attached to the mother plant for long periods after maturity, increasing their availability to naïve seed dispersers. The hypothesis that seed coat impermeability in many tropical Fabaceae with mimetic seeds serves as an exaptation to protect the seeds from deterioration and rotting while awaiting dispersal was investigated. Methods Seed coat impermeability was evaluated in five mimetic-seeded species of tropical Fabaceae in south-eastern Brazil (Abarema langsdorffii, Abrus precatorius, Adenanthera pavonina, Erythrina velutina and Ormosia arborea) and in Erythrina speciosa, a ‘basal’ species in its genus, which has monochromatic brown seeds and no mimetic displays. Seed hardness was evaluated as a defence against accelerated ageing (humid chamber at 41 °C for 144 h). Seed development and physiological potential of O. arborea was evaluated and the effect of holding mature seeds in pods on the mother plant in the field for a period of 1 year under humid tropical conditions was compared with seeds stored under controlled conditions (15 °C and 40 % relative air humidity). Key Results All five mimetic-seeded species, and E. speciosa, showed strong coat impermeability, which protected the seeds against deterioration in accelerated ageing. Most O. arborea seeds only became dormant 2 months after pod dehiscence. Germination of seeds after 1 year on the plant in a humid tropical climate was 56 %, compared with 80 % for seeds stored in controlled conditions (15 °C, 45 % relative humidity). Seedling shoot length after 1 year did not differ between seed sources. Conclusions Dormancy acts in mimetic-seeded species as an exaptation to reduce seed deterioration, allowing an increase in their effective dispersal period and mitigating the losses incurred by low

  16. Effects of a chitin binding vicilin from Erythrina velutina seeds on bean bruchid pests (Callosobruchus maculatus and Zabrotes subfasciatus).

    PubMed

    Teixeira, Fabiano M; Oliveira, Adeliana S; Macedo, Leonardo L P; Santos, Elizeu A; de Sales, Mauricio P

    2008-01-01

    Erythrina velutina vicilin, EvV, is a dimeric glycoprotein with Mr of 124.6 kDa. EvV was tested for anti-insect activity against bean bruchid larvae. EvV had LD(50) of 0.10% and ED(50) of 0.14% for Z. subfasciatus and LD(50) of 0.26% and ED(50) of 0.19% for C. maculatus. EvV was not digested by bean larvae enzymes until 12 h of incubation, and at 24 h EvV was more resistant to Z. subfasciatus enzymes.

  17. Isolation of quercetin from the methanolic extract of Lagerstroemia speciosa by HPLC technique, its cytotoxicity against MCF-7 cells and photocatalytic activity.

    PubMed

    Sai Saraswathi, V; Saravanan, D; Santhakumar, K

    2017-06-01

    The flavonoids present in the leaves of Lagerstroemia speciosa were extracted, characterized by spectral methods and studied for its cytotoxicity activity against MCF-cell lines and photocatalytic activity against azo dye. Direct and sequential soxhlet extraction was performed and its concentrated crude extract was subjected to high performance liquid chromatography. The yield obtained by the isolated compound (MEI-quercetin) from leaves of L. speciosa was found to be 1.8g from the methanolic extract. The phytochemical analysis and the Rf value of the isolated flavonoid was found to be 3.59. The isolated compound was characterized by Infrared Spectroscopy, NMR and Mass. Based on the characterization, the structure was elucidated as quercetin - a flavonoid. The isolated compound showed the significant in vitro cytotoxicity activity against MCF-7 cell lines at 500μg/ml when compared to the crude extract. Among the various concentrations (25, 50, 100, 250, and 500μg/ml), at higher concentration the cell viability was pronounced and also compared with that of the control. It was first time to report that the isolated flavonoid showed photocatalytic against azo dye-methyl orange. The dye degradation was monitored by UV-Vis spectrophotometry. The isolated compound showed dye degradation of 91.66% with the crude extract 82.47% at 160min. Hence in the present findings, the photocatalytic degradation of MO dye under UV irradiation was investigated over isolated compound of L. speciosa. Hence we expect that this can be used to treat the waste water in near future based on the photocatalytic technique. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. Hurricane Andrew: Impact on hazardous waste management

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kastury, S.N.

    1993-03-01

    On August 24, 1992, Hurricane Andrew struck the eastern coast of South Florida with winds of 140 mph approximately and a storm surge of 15 ft. The Florida Department of Environmental Regulation finds that the Hurricane Andrew caused a widespread damage throughout Dade and Collier County as well as in Broward and Monroe County and has also greatly harmed the environment. The Department has issued an emergency final order No. 92-1476 on August 26, 1992 to address the environmental cleanup and prevent any further spills of contaminants within the emergency area. The order authorizes the local government officials to designatemore » certain locations in areas remote from habitation for the open burning in air certain incinerators of hurricane generated yard trash and construction and demolition debris. The Department staff has assisted the county and FEMA staff in establishing procedures for Hazardous Waste Management, Waste Segregation and disposal and emergency responses. Local governments have issued these burn permits to public agencies including FDOT and Corps of Engineering (COE). Several case studies will be discussed on the Hazardous Waste Management at this presentation.« less

  19. Library Standards and Guidelines for Institutions Affiliated with or Offering Extension Programs of Andrews University.

    ERIC Educational Resources Information Center

    Brenneise, Harvey, Ed.; And Others

    Andrews University (Michigan), which is sponsored by the General Conference of Seventh-Day Adventists, extends its academic program to 14 other institutions, three in the United States and abroad. The program permits students in other countries to obtain a recognized, quality tertiary or graduate education. Andrews' research library, the James…

  20. Tectonic interpretation of the Andrew Bain transform fault: Southwest Indian Ocean

    NASA Astrophysics Data System (ADS)

    Sclater, John G.; Grindlay, Nancy R.; Madsen, John A.; Rommevaux-Jestin, Celine

    2005-09-01

    Between 25°E and 35°E, a suite of four transform faults, Du Toit, Andrew Bain, Marion, and Prince Edward, offsets the Southwest Indian Ridge (SWIR) left laterally 1230 km. The Andrew Bain, the largest, has a length of 750 km and a maximum transform domain width of 120 km. We show that, currently, the Nubia/Somalia plate boundary intersects the SWIR east of the Prince Edward, placing the Andrew Bain on the Nubia/Antarctica plate boundary. However, the overall trend of its transform domain lies 10° clockwise of the predicted direction of motion for this boundary. We use four transform-parallel multibeam and magnetic anomaly profiles, together with relocated earthquakes and focal mechanism solutions, to characterize the morphology and tectonics of the Andrew Bain. Starting at the southwestern ridge-transform intersection, the relocated epicenters follow a 450-km-long, 20-km-wide, 6-km-deep western valley. They cross the transform domain within a series of deep overlapping basins bounded by steep inward dipping arcuate scarps. Eight strike-slip and three dip-slip focal mechanism solutions lie within these basins. The earthquakes can be traced to the northeastern ridge-transform intersection via a straight, 100-km-long, 10-km-wide, 4.5-km-deep eastern valley. A striking set of seismically inactive NE-SW trending en echelon ridges and valleys, lying to the south of the overlapping basins, dominates the eastern central section of the transform domain. We interpret the deep overlapping basins as two pull-apart features connected by a strike-slip basin that have created a relay zone similar to those observed on continental transforms. This transform relay zone connects three closely spaced overlapping transform faults in the southwest to a single transform fault in the northeast. The existence of the transform relay zone accounts for the difference between the observed and predicted trend of the Andrew Bain transform domain. We speculate that between 20 and 3.2 Ma, an

  1. 1. Historic American Buildings Survey L. D. Andrew, Photographer (Enlarged ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey L. D. Andrew, Photographer (Enlarged by) Aug. 6, 1936 Photographed by Harold Bush-Brown SIDE VIEW - Covered Bridge, Spanning Soap Creek, Atlanta, Fulton County, GA

  2. Social Functioning of Kratom (Mitragyna speciosa) Users in Malaysia.

    PubMed

    Singh, Darshan; Müller, Christian P; Vicknasingam, Balasingam K; Mansor, Sharif M

    2015-01-01

    Kratom (Mitragyna speciosa) is an indigenous plant known for its traditional medicinal use, and for its addiction potential, in Southeast Asia. In recent years, kratom and its major alkaloid, mitragynine, spread worldwide with largely unknown effects on behavior and mental health. Recent studies show that kratom use can lead to dependence and that mitragynine works as an addictive drug in animal studies. Nevertheless, kratom preparations were also suggested as a less harmful substitute in opiate withdrawal. Potential side-effects of prolonged kratom use, however, are currently unclear. The aim of this study was to investigate the social functioning of regular kratom users in Malaysia. A cross-sectional survey was carried out in three northern states of Peninsular Malaysia investigating 293 regular kratom consumers using the Addiction Severity Index in a snowball sampling technique. Findings showed that regular kratom users do not experience major impairments in their social functioning, despite being dependent on kratom for prolonged periods. Our findings suggest that chronic kratom administration does not significantly impair social functioning of users in a natural context in Malaysia.

  3. 1. Historic American Buildings Survey L. D. Andrew, Photographer Enlarged ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey L. D. Andrew, Photographer Enlarged Photographed by Harold Bush-Brown Nov. 14, 1936 GENERAL VIEW OF SLAVE CABINS - Bass Place (Slave Cabins), Columbus, Muscogee County, GA

  4. 2. Historic American Buildings Survey L. D. Andrew, Photographer, Enlarged ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Historic American Buildings Survey L. D. Andrew, Photographer, Enlarged Photographed by Harold Bush-Brown Nov. 14, 1936 VIEW OF EASTERN SLAVE CABIN - Bass Place (Slave Cabins), Columbus, Muscogee County, GA

  5. 1. Historic American Buildings Survey L. D. Andrew, Photographer Enlarged ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey L. D. Andrew, Photographer Enlarged from picture photographed by Harold Bush-Brown Aug. 1936 VIEW OF FRONT AND RIGHT SIDE - Old Methodist Church, Roswell, Fulton County, GA

  6. The McAndrews Leadership Lecture: February 2015, by Dr Scott Haldeman. Challenges of the Past, Challenges of the Present

    PubMed Central

    Haldeman, Scott; McAndrews, George P.; Goertz, Christine; Sportelli, Louis; Hamm, Anthony W.; Johnson, Claire

    2015-01-01

    The McAndrews Leadership Lecture was developed by the American Chiropractic Association to honor the legacy of Jerome F. McAndrews, DC, and George P. McAndrews, JD, and their contributions to the chiropractic profession. This article is a transcription of the presentation made by Dr Scott Haldeman on February 28, 2015, in Washington, DC, at the National Chiropractic Leadership Conference. PMID:26770177

  7. STS-75 Mission Commander Andrew M. Allen in White Room

    NASA Technical Reports Server (NTRS)

    1996-01-01

    STS-75 Mission Commander Andrew M. Allen (center) prepares to enter the Space Shuttle Columbia at Launch Pad 39B with assistance from white room closeout crew members Paul Arnold (left), Dave Law and Bob Saulnier.

  8. Antimicrobial activity of flavanoid sulphates and other fractions of Argyreia speciosa (Burm.f) Boj.

    PubMed

    Habbu, P V; Mahadevan, K M; Shastry, R A; Manjunatha, H

    2009-02-01

    Antimicrobial activity of flavanoid sulphates and different fractions of A. speciosa root was studied against bacteria, fungi and Mycobacterium tuberculosis H37 Rv sensitive strain by in vitro and in vivo assays. Flavanoid sulphates such as quercetin 3'7 di-O methyl 3- sulphate and kaempferol 7-O methyl 3-sulphate were isolated from the n-butanol fraction of 80% methanolic extract of the plant. The structures of the isolated flavanoids were confirmed by spectral studies. Ethyl acetate (EAAS) fraction and flavanoid sulphates inhibited the growth of M. tuberculosis Rv sensitive strain at MIC values 50 and 25 microg/ml, respectively. Ethanolic fraction (EtAS) showed significant inhibition of gram positive organism with a MIC of 31.25 microg/ml. More inhibition was observed with a less MIC (2 microg/ml) for flavanoid sulphates against Klebsiella pneumoniae, a gram negative organism and it is almost comparable with the standards. Interestingly, chloroform fraction alone exhibited significant antifungal activity with a MIC of 100 microg/ml. A synergistic effect between flavanoids sulphates and commercially available antitubercular drugs was observed with FIC index of 0.443 +/- 0.245, 0.487 +/- 0.247 for isoniazid and 0.468 +/- 0.333, 0.417 +/- 0.345 for rifampicin, whereas EAAS fraction showed partial synergistic effect. A synergistic effect was observed for EAAS fraction and flavanoids sulphates with FIC index < 0.5 with antibiotics. Hemolysis assay on RBCs suggested that EAAS and flavanoids sulphates exhibited least cellular toxicity to erythrocytes as compared to chloramphenicol. In vivo studies in mice infected with K. pneumoniae demonstrated that on day 10 post treatment of different fractions and isolated compounds of A. speciosa, about 60% of the animals treated with EAAS, 70% of animals treated with flavanoids sulphates and 40% of animals treated with EtAS were survived.

  9. Astronaut Andrew Allen monitors Columbia's systems from pilots station

    NASA Image and Video Library

    1994-03-05

    STS062-41-025 (18 March 1994) --- Astronaut Andrew M. Allen monitors Columbia's systems from the pilot's station during the entry phase of the STS-62 mission. The fast-speed 35mm film highlights the many controls and displays and the cathode ray tubes on the forward flight deck.

  10. Photomorphogenesis in Sinningia speciosa, cv. Queen Victoria I. Characterization of Phytochrome Control.

    PubMed

    Satter, R L; Wetherell, D F

    1968-06-01

    The morphological development of Sinningia speciosa plants that were exposed to supplementary far red light was very different from that of plants receiving dark nights. After several nights of such irradiation, stems and petioles were elongated, petioles were angulated, leaf blade expansion was inhibited, plants were chlorotic and the accumulation of shoot dry weight was retarded.Red reversibility of the morphological changes potentiated by far red light indicated control by the phytochrome system. A high P(FR) level during the last half of the night inhibited stem elongation and promoted leaf blade expansion, but both of these processes were hardly affected by the P(FR) level during the first half of the night. Thus sensitivity to P(FR) was cyclic.The interpretation of our experiments was complicated by quantitative morphological differences resulting from long, as compared to short, far red irradiations.

  11. EDA's post-disaster assistance program after hurricane Andrew : final report.

    DOT National Transportation Integrated Search

    1996-03-01

    Hurricane Andrew devastated parts of South Florida in August 1992, causing $20 billion in property damage, killing at least 41 people, and injuring many more. EDA joined other federal agencies in the disaster recovery process by promptly sending a te...

  12. Andrew Wyeth and N.C. Wyeth: a psychodynamic perspective on father and son.

    PubMed

    Shaw, Jon A

    2013-01-01

    This paper examines the relationship between two extraordinary artists, father and son--N.C. Wyeth (1882-1945) and Andrew Wyeth (1917-2009)--and their art. N.C. Wyeth, the father, the most famous illustrator of his day, painted scenes full of drama and action, often of men engaged in violent life and death struggles. N.C. was unable to separate from his powerful mother and yearned for his iconic father. He thought himself an artistic failure and dedicated himself to raising his children to be geniuses. The youngest son, Andrew Wyeth, who lived a "secret life," painted scenes often characterized by pathos: bleak and barren landscapes, leaden skies, tire tracks, gray framed houses, desiccated fields, and circling buzzards. In the father-son relationship, we often seen three themes perpetuated developmentally: (1) the son's identification with the innermost conflicts of his father; (2) the yearning for the iconic father of his youth; and (3) a continuation and disavowal of his father's life. These themes are played out in the relationship between Andrew Wyeth and his father.

  13. Astronaut Andrew M. Allen monitors Columbia's systems from pilots station

    NASA Technical Reports Server (NTRS)

    1994-01-01

    Astronaut Andrew M. Allen monitors Columbia's systems from the pilot's station during the entry phase of the STS-62 mission. The fast-speed 35mm film highlights the many controls and displays and the cathode ray tubes on the forward flight deck.

  14. Astronaut Andrew M. Allen looks over procedure book in middeck

    NASA Technical Reports Server (NTRS)

    1994-01-01

    On Columbia's middeck, astronaut Andrew M. Allen, pilot, looks over a procedures book in the midst of a 14-day mission. Allen is attired in a new thermally controlled undergarment. Allen wore the garment during the launch and entry phases of the flight.

  15. Appreciating Unity in Diversity: An Interview with Andrew Solomon

    ERIC Educational Resources Information Center

    Peters, Dane L.

    2014-01-01

    The theme of the AMS 2014 Annual Conference is "Unity in Diversity," a concept that also describes the work of conference keynote speaker Andrew Solomon. Solomon is a writer and lecturer on psychology and politics; winner of the National Book Award; and an activist for LGBT [lesbian, gay, bisexual, and transgender] rights, mental health,…

  16. Bioassay-guided isolation of novel compound from Paeonia suffruticosa Andrews roots as an IL-1β inhibitor.

    PubMed

    Choi, Yun-Hyeok; Yoo, Hee-Jung; Noh, Ill Chan; Lee, Jeong-Min; Park, Jae Won; Choi, Wahn Soo; Choi, Jung Ho

    2012-05-01

    The inhibition of Interleukin-1beta (IL-1β) is of substantial interest for the treatment of rheumatoid arthritis. Using an in vitro assay with RAW 264.7 cells, oxo-acetic acid 2-ethoxy-4-(3-hydroxy-2-oxopropyl) phenyl ester (1) was isolated from the roots of Paeonia suffruticosa Andrews as an inhibitor of IL-1β with an IC(50) value of 56 μM. Compound 1 is a novel phenylesteric compound from P. suffruticosa Andrews. Compound 1 was shown to inhibit the production of pro-inflammatory cytokines in RAW 264.7 cells. Thus, a possible new action of novel compound is provided explaining the anti-rheumatoid arthritic properties of P. suffruticosa Andrews.

  17. STS-77 MS Andrew Thomas suits up

    NASA Technical Reports Server (NTRS)

    1996-01-01

    STS-77 Mission Specialist Andrew S. W. Thomas finishes donning his launch/entry suit in the Operations and Checkout Building with assistance from a suit technician. A native of South Australia, the rookie astronaut joins a crew of five veterans on the fourth Shuttle flight of 1996. They will depart shortly for Launch Pad 39B, where the Space Shuttle Endeavour is undergoing final preparations for liftoff during a two-and-a-half hour launch window opening at 6:30 a.m. EDT, May 19.

  18. Trait differences in responses to arbuscular mycorrhizal fungi are stronger and more consistent than fixed differences among populations of Asclepias speciosa.

    PubMed

    Waller, Lauren P; Hahn, Philip G; Maron, John L; Lekberg, Ylva

    2018-02-01

    Arbuscular mycorrhizal (AM) fungi can promote plant growth and reproduction, but other plant physiological traits or traits that provide defense against herbivores can also be affected by AM fungi. However, whether responses of different traits to AM fungi are correlated and whether these relationships vary among plants from different populations are unresolved. In a common garden experiment, we grew Asclepias speciosa plants from seed collected from populations found along an environmental gradient with and without AM fungi to assess whether the responses of six growth and defense traits to AM fungi are correlated. Although there was strong genetic differentiation in mean trait values among populations, AM fungi consistently increased expression of most growth and defense traits across all populations. Responses of biomass and root to shoot ratio to AM fungi were positively correlated, suggesting that plants that are more responsive to AM fungi allocated more biomass belowground. Responses of biomass and trichome density to AM fungi were negatively correlated, indicating a trade-off in responsiveness between a growth and defensive trait. Our results suggest that while there is substantial population differentiation in many traits of A. speciosa, populations respond similarly to AM fungi, and both positive and negative correlations among trait responses occur. © 2018 Botanical Society of America.

  19. Capacities of template-type platforms in the Gulf of Mexico during hurricane Andrew

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bea, R.G.; Loch, K.J.; Young, P.L.

    1997-02-01

    This paper details results from nonlinear analyses of the ultimate limit state performance characteristics of four Gulf of Mexico (GOM) platforms subjected to intense loadings from hurricane Andrew. These four platforms were located to the east of the track of hurricane Andrew, and were thus in the most intense portion of the storm (Smith, 1993). The nonlinear analyses are able to replicate details of the observed behavior of the four structures. This replication is very dependent on realistic characterization of the performance characteristics of the pile foundations and on accurate information on the as is condition of the platforms beforemore » the storm.« less

  20. Andrew spares Florida Coast

    NASA Astrophysics Data System (ADS)

    Bush, Susan

    When geologists heard of the intensity of Hurricane Andrew, which struck the Florida coast on August 25 and then moved on to southern Louisiana, they were expecting the same kinds of coastal damage that Hurricane Hugo brought to the Caribbean and Carolina shores in 1989. Both storms were category 4 hurricanes, having winds of 131-155 mph and surges of 13-18 feet. However, the coastal damage never materialized, leaving geologists to analyze the factors that lessened the impact of the storm. “For minimum coastal damage, you couldn't have designed a better storm,” said Orrin Pilkey, director of the Program for the Study of Developed Shorelines (PSDS) in Durham, N.C. This was due in part to the nature of the storm itself and where it hit land, and in part to the regional geology, said Rob Thieler of PSDS. Despite the huge amounts of damage to buildings, there was virtually no evidence of coastal process destruction, he said.

  1. Antisecretory Action of the Extract of the Aerial Parts of Eremomastax speciosa (Acanthaceae) Occurs through Antihistaminic and Anticholinergic Pathways.

    PubMed

    André Perfusion, Amang; Tan, Paul V; Ernestine, Nkwengoua; Barthélemy, Nyasse

    2014-01-01

    Objective. The objective of this study was to find out the possible antiulcer mechanism of action of Eremomastax speciosa. Method. Carbachol- and histamine-induced hypersecretion, associated with the pylorus ligation technique, were used in rats. Gastric mucosal ulceration, mucus production, pH, gastric volume, and acidity were measured. Results. Histamine and carbachol raised gastric acidity to 86.50 and 84.80 mEq/L, respectively, in the control rats, and the extracts (200 mg/kg) reduced gastric acidity to 34.60 and 39.00 mEq/L, respectively. Intraduodenal aqueous extract (400 mg/kg) in histamine- and carbachol-treated rats produced significant (P < 0.001) decreases in acid secretion to 28.50 and 28.80 mEq/L, respectively, and 100 percent inhibition of gastric ulceration. Augmented histamine-induced gastric acid secretion (90.20 mEq/L) was significantly reduced to 52.60 and 27.50 mEq/L by the 200 and 400 mg/kg doses of the aqueous extract, respectively. The extract significantly reduced (P < 0.001) the volume of gastric secretion and significantly increased mucus production. The ulcer inhibition potential of the extract significantly dropped to 25-44% (oral extract) and to 29-37% (duodenal extract) in carbachol/indomethacin-treated rats. Conclusion. The aqueous extract of E. speciosa has both cytoprotective and antisecretory effects. The antisecretory effect may involve a mechanism common to both cholinergic and histaminergic pathways.

  2. STS-75 Mission Cmdr Andrew Allen arrives at SLF

    NASA Technical Reports Server (NTRS)

    1996-01-01

    STS-75 Mission Commander Andrew M. Allen arrives at KSC's Shuttle Landing Facility. Altogether seven crew members are assigned to the second Shuttle flight of 1996, which will be highlighted by the re-flight of the Italian Tethered Satellite System (TSS-1R). Liftoff is slated to occur during a two-and-a-half window opening at 3:18 p.m. EST, Feb. 22.

  3. STS-75 Mission Commander Andrew M. Allen suits up

    NASA Technical Reports Server (NTRS)

    1996-01-01

    STS-75 Mission Commander Andrew M. Allen completes suitup activities in the Operations and Checkout Building. STS-75 will be Allen's third trip into space, his first as commander. Allen and an international crew will depart shortly for Launch Pad 39B, where the Space Shuttle Columbia awaits liftoff during a two-and- a-half-hour launch window opening at 3:18 p.m. EST.

  4. Astronaut Andrew Allen looks over procedure book in middeck

    NASA Image and Video Library

    1994-03-05

    STS062-12-015 (4-18 March 1994) --- On Coumbia's middeck, astronaut Andrew M. Allen, pilot, looks over a procedures book in the midst of a 14-day mission. Allen is attired in a new thermally controlled undergarment. As part of a detailed test objective, both Allen and John H. Casper, mission commander, wore the undergarments during the launch and entry phases of the flight.

  5. Synthesis, characterization and application of Lagerstroemia speciosa embedded magnetic nanoparticle for Cr(VI) adsorption from aqueous solution.

    PubMed

    Srivastava, Shalini; Agrawal, Shashi Bhushan; Mondal, Monoj Kumar

    2017-05-01

    Lagerstroemia speciosa bark (LB) embedded magnetic nanoparticles were prepared by co-precipitation of Fe 2+ and Fe 3+ salt solution with ammonia and LB for Cr(VI) removal from aqueous solution. The native LB, magnetic nanoparticle (MNP), L. speciosa embedded magnetic nanoparticle (MNPLB) and Cr(VI) adsorbed MNPLB particles were characterized by SEM-EDX, TEM, BET-surface area, FT-IR, XRD and TGA methods. TEM analysis confirmed nearly spherical shape of MNP with an average diameter of 8.76nm and the surface modification did not result in the phase change of MNP as established by XRD analysis, while led to the formation of secondary particles of MNPLB with diameter of 18.54nm. Characterization results revealed covalent binding between the hydroxyl group of MNP and carboxyl group of LB particles and further confirmed its physico-chemical nature favorable for Cr(VI) adsorption. The Cr(VI) adsorption on to MNPLB particle as an adsorbent was tested under different contact time, initial Cr(VI) concentration, adsorbent dose, initial pH, temperature and agitation speed. The results of the equilibrium and kinetics of adsorption were well described by Langmuir isotherm and pseudo-second-order model, respectively. The thermodynamic parameters suggest spontaneous and endothermic nature of Cr(VI) adsorption onto MNPLB. The maximum adsorption capacity for MNPLB was calculated to be 434.78mg/g and these particles even after Cr(VI) adsorption were collected effortlessly from the aqueous solution by a magnet. The desorption of Cr(VI)-adsorbed MNPLB was found to be more than 93.72% with spent MNPLB depicting eleven successive adsorption-desorption cycles. Copyright © 2016. Published by Elsevier B.V.

  6. 78 FR 76812 - In the Matter of: Andrew Vincent O'Donnell, Inmate Number-62355-019, USP Atlanta, U.S...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-19

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security In the Matter of: Andrew Vincent O'Donnell, Inmate Number--62355- 019, USP Atlanta, U.S. Penitentiary, P.O. Box 15060, Atlanta, GA 30315; Order..., Andrew Vincent O'Donnell (``O'Donnell''), was convicted of violating Section 38 of the Arms Export...

  7. GRAHAM NELSON AND ANDREW HANKS WITH BREADBOARD ENGINE PROJECT CO

    NASA Image and Video Library

    2016-09-14

    Graham Nelson, right, and Andrew Hanks examine a combustion chamber developed by engineers at NASA's Marshall Space Flight Center in Huntsville, Alabama, for an additively manufactured demonstration breadboard engine project. Nelson is project manager and Hanks is test lead for the project, in which engineers are designing components from scratch to be made entirely by 3-D printing.

  8. Thylakoid membrane landscape in the sixties: a tribute to Andrew Benson.

    PubMed

    Anderson, Jan M

    2007-05-01

    Prior to the 1960s, the model for the molecular structure of cell membranes consisted of a lipid bilayer held in place by a thin film of electrostatically-associated protein stretched over the bilayer surface: (the Danielli-Davson-Robertson "unit membrane" model). Andrew Benson, an expert in the lipids of chloroplast thylakoid membranes, questioned the relevance of the unit membrane model for biological membranes, especially for thylakoid membranes, instead of emphasizing evidence in favour of hydrophobic interactions of membrane lipids within complementary hydrophobic regions of membrane-spanning proteins. With Elliot Weier, Benson postulated a remarkable subunit lipoprotein monolayer model for thylakoids. Following the advent of freeze fracture microscopy and the fluid lipid-protein mosaic model by Singer and Nicolson, the subunits, membrane-spanning integral proteins, span a dynamic lipid bilayer. Now that high resolution X-ray structures of photosystems I and II are being revealed, the seminal contribution of Andrew Benson can be appreciated.

  9. Andrewes's christmas fairy tale: atypical thinking about cancer aetiology in 1935

    PubMed Central

    Sankaran, Neeraja; van Helvoort, Ton

    2016-01-01

    This paper uses a short ‘Christmas fairy-story for oncologists’ sent by Christopher Andrewes with a 1935 letter to Peyton Rous as the centrepiece of a reflection on the state of knowledge and speculation about the viral aetiology of cancer in the 1930s. Although explicitly not intended for public circulation at the time, the fairy-story merits publication for its significance in the history of ideas about viruses, which are taken for granted today. Andrewes and Rous were prominent members of the international medical research community and yet faced strong resistance to their theory that viruses could cause such tumours as chicken sarcomas and rabbit papillomas. By looking at exchanges between these men among themselves and other proponents of their theories and with their oncologist detractors, we highlight an episode in the behind-the-scenes workings of medical science and show how informal correspondence helped keep alive a vital but then heterodox idea about the role of viruses in causing cancer. PMID:27386716

  10. Biofilm inhibition formation of clinical strains of Pseudomonas aeruginosa mutans, photocatalytic activity of azo dye and GC-MS analysis of leaves of Lagerstroemia speciosa.

    PubMed

    Sai Saraswathi, V; Kamarudheen, Neethu; Bhaskara Rao, K V; Santhakumar, K

    2017-04-01

    The investigation was conducted to analyse the bioactive compounds from the leaf extracts of L. speciosa by GC-MS. The extracts were screened for antibacterial and antibiofilm activities against potential clinical strains. The bioactive compounds from the leaves of L. speciosa were extracted by soxhlet continuous extraction method and their chemical composition was analysed by Gas Chromatography-Mass Spectroscopy (GC-MS). The antibacterial activity was evaluated against clinical strain like Staphylococcus aureus, Escherichia coli, P. aeruginosa and Salmonella typhi by well diffusion technique. We also screened for antibacterial property against common food borne pathogens namely Listeria monocytogenes and Bacillus cereus at varied concentration 250μml -1 to 1000μml -1 . Thereafter antibiofilm assay was carried out at from 250 to 1000μg/ml against P. aeruginosa (high biofilm forming pathogen) clinical strain by cover slip technique and the morphology of the pathogen was observed using Scanning Electron Microscopy-(SEM). It was observed that diverse class of secondary metabolites were found by GC-MS analysis for all the extracts upon the continuous extraction. It was found that only minimum inhibition was seen in alcoholic extract for antibacterial activity, whereas all other extracts showed negligible activity. P. aeruginosa biofilm inhibited to 93.0±2% and 91±2% at higher concentration (1000μg/ml) for methanolic and ethanolic extract respectively. Absence of extracellular matrix structure and the surface cracking of biofilm were viewed by SEM, which confirmed the antibiofilm activity. Hence this study reveals that L. speciosa showed significant antibiofilm activity against P. aeruginosa due to the phytoconstituents present in the leaf extracts which was well documented in the alcoholic extracts by GC-MS analysis. The methanolic and ethanolic extract showed good photocatalytic activity of 77.44% and 96.66% against azo dye degradation respectively. Further

  11. Because Everyone Has a Story to Tell: Interview with Andrew Wright

    ERIC Educational Resources Information Center

    Floris, Flora Debora

    2016-01-01

    This article presents an interview with Andrew Wright, a widely recognized author, illustrator, storyteller, and teacher trainer. Wright has published many ELT books, authored six "Spellbinder" graded readers (1992-1994), and a collection of short stories. As a teacher trainer, Wright worked extensively with both teachers and students in…

  12. Segmentation and Accretionary Processes Near the Andrew Bain Mega-Transform Fault: The Southwest Indian Ridge 25°-35°E

    NASA Astrophysics Data System (ADS)

    Takeuchi, C. S.; Sclater, J. G.; Grindlay, N. R.; Madsen, J. A.; Rommevaux-Jestin, C.

    2008-12-01

    The ultra-slow spreading Southwest Indian Ridge (SWIR) separates the Antarctic and African plates. We present results from two surveys covering the SWIR between 26° and 27°30'E and between 32° and 35°E, lying on either side of the long-offset Andrew Bain transform fault. The objectives of the surveys were to characterize the segmentation of an ultra-slow spreading ridge on either side of a long-offset transform fault and to examine the structure of the individual segments. Four transform faults, the Du Toit, Andrew Bain, Marion, and Prince Edward, and one non-transform discontinuity bound four accretionary segments in the survey areas. Two segments lie northeast of the Andrew Bain (32°-35°E). Large central axial volcanoes, deep, broad mantle Bouguer anomaly (MBA) lows, and high magnetization intensities centered on the spreading axis result from high magmatic activity. Increased magmatism on the ridge axis is likely caused by high mantle temperatures produced by the close proximity of the Marion Plume, which abuts the northern end of the Andrew Bain. Two segments lie southwest of the Andrew Bain (26°-27°30'E). Discrepancies in the locations of the axial rift valley, central magnetization high, and an irregularly-shaped MBA low suggest complex accretionary processes at the western segment (~26°-27° E). The eastern segment (~27°-27°30'E), which abuts the southwest end of the Andrew Bain, shows a deep axial valley, MBA values which increase to the east, and nearly nonexistent magnetization intensity. These features are probably the result of amagmatic accretion caused by the transform edge effect of the Andrew Bain. A transition in the character of topography at 26°45'E suggests that the current segment configuration may not be temporally stable. High-relief (~1 km) ridge-trough structures south of the spreading axis may be the result of an episodic interplay between accretion, both magmatic and amagmatic, and tectonic extension.

  13. Erythrina excelsa exhibits estrogenic effects in vivo and in vitro and is cytotoxic on breast and colon cancer cell lines.

    PubMed

    Tchoukouegno Ngueu, Sadrine; Tchoumtchoua, Job; Njamen, Dieudonné; Halabalaki, Maria; Laudenbach-Leschowski, Ute; Diel, Patrick

    2016-01-01

    Eythrina excelsa Baker (Fabaceae) is a medicinal plant used to treat various ailments including those of the female genital tract. The objective of this study is to investigate the estrogenic and cytotoxic effects of the ethanol extract of the stem bark of E. excelsa. Erythrina excelsa was evaluated in vitro using the yeast estrogen screen (YES). The extract was then tested in a 3-day uterotrophic assay on ovariectomised Wistar rats at doses of 50 and 100 mg/kg BW/d. Cytotoxic effects were assessed on breast (MCF-7) and colon (HT-29) cancer cell lines using the MTT cell viability assay. Additionally, a LC-PDA-ESI (+)-HRMS and HRMS/MS method was developed and applied for the identification of representative secondary metabolites scaffolds in the extract. In the YES, the extract stimulated the transactivation of the estrogen receptor in a dose-dependent manner with an EC50 value of 1.8 μg/mL. In rats, E. excelsa increased uterine wet weight, uterine epithelial height, and the mRNA expression of estrogen-responsive genes in the uterus and liver at 50 whereas at 100 mg/kg BW/d anti-estrogenic effects were observed. In the MTT-assay, a dose-dependent decrease of the viability of both cell lines was observed with EC50 values of 13.6 μg/mL (MCF-7) and 27.7 μg/mL (HT-29). The phytochemical analysis revealed that the extract is rich in isoflavonoids, mainly prenylated and pyran-derivatives thereof. Erythrina excelsa is rich in prenylated and pyran-substituted isoflavonoids, exhibits estrogenic/anti-estrogenic and cytotoxic effects and warrant sufficient interest for deeper investigations.

  14. STS-75 Mission Cmdr Andrew Allen talks to media

    NASA Technical Reports Server (NTRS)

    1996-01-01

    STS-75 Mission Commander Andrew M. Allen talks to news media gathered at KSC's Shuttle Landing Facility for the flight crew's arrival. Altogether seven crew members are assigned to the second Shuttle flight of 1996, which will be highlighted by the re- flight of the Italian Tethered Satellite System (TSS-1R). Liftoff is slated to occur during a two-and-a-half window opening at 3:18 p.m. EST, Feb. 22.

  15. Water uptake mechanism and germination of Erythrina velutina seeds treated with atmospheric plasma

    NASA Astrophysics Data System (ADS)

    Alves Junior, Clodomiro; de Oliveira Vitoriano, Jussier; da Silva, Dinnara Layza Souza; de Lima Farias, Mikelly; de Lima Dantas, Nadjamara Bandeira

    2016-09-01

    The effect of plasma applied to mulungu (Erythrina velutina) seeds was studied to verify its influence on the germination, water absorption, wettability and structure of the seeds. The plasma jet used in this study was produced by dielectric barrier discharge (DBD) in a helium gas flow of 0.03 L/s at a distance of 13 mm for 60 s. The plasma treatment significantly affected the seed germination rate, which was approximately 5% higher than that of the untreated group. Micropyle and hilum contributed a greater proportion to uptake. When sealed in the hilar or micropyle regions the amount of water absorbed into the seed decreased approximately 75% compared to the unsealed seed. This difference suggests that these two regions together act cooperatively in the water absorption. However, when plasma treated seed was blocked in the micropyle region, water absorption was higher higher than in seeds blocked hilum. This difference suggests that the plasma treatment changed the wettability of the hilum more effectively than it changed the micropyle. These results indicate that plasma can significantly change the hydrophilicity, water absorption and percentage of seed germination in E. velutina.

  16. 23. View of open firststory passageway of Andrew McLean Company ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    23. View of open first-story passageway of Andrew McLean Company Textile Mill Building No. 1, looking west - Dundee Canal Industrial Historic District, Beginning at George Street in Passaic & extending north along Dundee Canal approximately 1.2 miles to Canal headgates opposite East Clifton Avenue in Clifton, Passaic, Passaic County, NJ

  17. 30. View looking north from Andrew McLean Company Textile Mill; ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    30. View looking north from Andrew McLean Company Textile Mill; Dundee Canal at center, Botany Worsted Mills in background - Dundee Canal Industrial Historic District, Beginning at George Street in Passaic & extending north along Dundee Canal approximately 1.2 miles to Canal headgates opposite East Clifton Avenue in Clifton, Passaic, Passaic County, NJ

  18. 31. View looking north from Andrew McLean Company Textile Mill; ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    31. View looking north from Andrew McLean Company Textile Mill; Dundee Canal at center, Botany Worsted Mills in background - Dundee Canal Industrial Historic District, Beginning at George Street in Passaic & extending north along Dundee Canal approximately 1.2 miles to Canal headgates opposite East Clifton Avenue in Clifton, Passaic, Passaic County, NJ

  19. 15. View of Andrew McLean Company Textile Mill looking northeast; ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. View of Andrew McLean Company Textile Mill looking northeast; Building No. 1 at left, Building No. 6 at center - Dundee Canal Industrial Historic District, Beginning at George Street in Passaic & extending north along Dundee Canal approximately 1.2 miles to Canal headgates opposite East Clifton Avenue in Clifton, Passaic, Passaic County, NJ

  20. 20. View of Andrew McLean Company Textile Mill looking southeast; ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. View of Andrew McLean Company Textile Mill looking southeast; Building No. 2 at left, Building No. 3 at right - Dundee Canal Industrial Historic District, Beginning at George Street in Passaic & extending north along Dundee Canal approximately 1.2 miles to Canal headgates opposite East Clifton Avenue in Clifton, Passaic, Passaic County, NJ

  1. 22. View of Andrew McLean Company Textile Mill looking north; ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. View of Andrew McLean Company Textile Mill looking north; Building No. 1 at left, Building No. 4 at right - Dundee Canal Industrial Historic District, Beginning at George Street in Passaic & extending north along Dundee Canal approximately 1.2 miles to Canal headgates opposite East Clifton Avenue in Clifton, Passaic, Passaic County, NJ

  2. 17. View looking north; Andrew McLean Company Textile Mill, Building ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. View looking north; Andrew McLean Company Textile Mill, Building No. 1, at right, Botany Worsted Mills at left distance - Dundee Canal Industrial Historic District, Beginning at George Street in Passaic & extending north along Dundee Canal approximately 1.2 miles to Canal headgates opposite East Clifton Avenue in Clifton, Passaic, Passaic County, NJ

  3. 56. Aerial view looking west; Andrew McLean Company Textile Mill ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    56. Aerial view looking west; Andrew McLean Company Textile Mill at bottom, Dundee Canal at center, Botany Worsted Mills at top - Dundee Canal Industrial Historic District, Beginning at George Street in Passaic & extending north along Dundee Canal approximately 1.2 miles to Canal headgates opposite East Clifton Avenue in Clifton, Passaic, Passaic County, NJ

  4. 33 CFR 334.680 - Gulf of Mexico, southeast of St. Andrew Bay East Entrance, small-arms firing range, Tyndall Air...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Gulf of Mexico, southeast of St... AND RESTRICTED AREA REGULATIONS § 334.680 Gulf of Mexico, southeast of St. Andrew Bay East Entrance... the Gulf of Mexico, southeast of St. Andrew Bay East Entrance within a rectangular area beginning at a...

  5. 33 CFR 334.680 - Gulf of Mexico, southeast of St. Andrew Bay East Entrance, small-arms firing range, Tyndall Air...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 3 2014-07-01 2014-07-01 false Gulf of Mexico, southeast of St... AND RESTRICTED AREA REGULATIONS § 334.680 Gulf of Mexico, southeast of St. Andrew Bay East Entrance... the Gulf of Mexico, southeast of St. Andrew Bay East Entrance within a rectangular area beginning at a...

  6. 33 CFR 334.680 - Gulf of Mexico, southeast of St. Andrew Bay East Entrance, small-arms firing range, Tyndall Air...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 3 2013-07-01 2013-07-01 false Gulf of Mexico, southeast of St... AND RESTRICTED AREA REGULATIONS § 334.680 Gulf of Mexico, southeast of St. Andrew Bay East Entrance... the Gulf of Mexico, southeast of St. Andrew Bay East Entrance within a rectangular area beginning at a...

  7. 33 CFR 334.680 - Gulf of Mexico, southeast of St. Andrew Bay East Entrance, small-arms firing range, Tyndall Air...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Gulf of Mexico, southeast of St... AND RESTRICTED AREA REGULATIONS § 334.680 Gulf of Mexico, southeast of St. Andrew Bay East Entrance... the Gulf of Mexico, southeast of St. Andrew Bay East Entrance within a rectangular area beginning at a...

  8. 33 CFR 334.680 - Gulf of Mexico, southeast of St. Andrew Bay East Entrance, small-arms firing range, Tyndall Air...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 3 2012-07-01 2012-07-01 false Gulf of Mexico, southeast of St... AND RESTRICTED AREA REGULATIONS § 334.680 Gulf of Mexico, southeast of St. Andrew Bay East Entrance... the Gulf of Mexico, southeast of St. Andrew Bay East Entrance within a rectangular area beginning at a...

  9. Building a "cyber forest" in complex terrain at the Andrews Experimental Forest

    Treesearch

    Donald L. Henshaw; Fred Bierlmaier; Barbara J. Bond; Kari B. O' Connell

    2008-01-01

    Our vision for a future "cyber forest" at the Andrews Experimental Forest foresees high performance wireless communications enhancing connectivity among remote field research locations, station headquarters, and beyond to the university and outside world. New sensor technologies and collaboration tools foretell exponential increases in data and information...

  10. Antimicrobial, Antioxidant and Cytotoxic Activity of Silver Nanoparticles Synthesized by Leaf Extract of Erythrina suberosa (Roxb.).

    PubMed

    Mohanta, Yugal K; Panda, Sujogya K; Jayabalan, Rasu; Sharma, Nanaocha; Bastia, Akshaya K; Mohanta, Tapan K

    2017-01-01

    In this experiment, biosynthesized silver nanoparticles (AgNPs) were synthesized using aqueous leaf extract of Erythrina suberosa (Roxb.). The biosynthesis of silver nanoparticle was continuously followed by UV-vis spectrophotometric analysis. The response of the phytoconstituents resides in E. suberusa during synthesis of stable AgNPs were analyzed by ATR- fourier-transform infrared spectroscopy. Further, the size, charge, and polydispersity nature of AgNPs were studied using dynamic light scattering spectroscopy. The morphology of the nanoparticles was determined by scanning electron microscopy. Current result shows core involvement of plant extracts containing glycosides, flavonoids, and phenolic compounds played a crucial role in the biosynthesis of AgNPs. The antimicrobial activities of silver nanoparticles were evaluated against different pathogenic bacterium and fungi. The antioxidant property was studied by radical scavenging (DPPH) assay and cytotoxic activity was evaluated against A-431 osteosarcoma cell line by MTT assay. The characteristics of the synthesized silver nanoparticles suggest their application as a potential antimicrobial and anticancer agent.

  11. Antimicrobial, Antioxidant and Cytotoxic Activity of Silver Nanoparticles Synthesized by Leaf Extract of Erythrina suberosa (Roxb.)

    PubMed Central

    Mohanta, Yugal K.; Panda, Sujogya K.; Jayabalan, Rasu; Sharma, Nanaocha; Bastia, Akshaya K.; Mohanta, Tapan K.

    2017-01-01

    In this experiment, biosynthesized silver nanoparticles (AgNPs) were synthesized using aqueous leaf extract of Erythrina suberosa (Roxb.). The biosynthesis of silver nanoparticle was continuously followed by UV-vis spectrophotometric analysis. The response of the phytoconstituents resides in E. suberusa during synthesis of stable AgNPs were analyzed by ATR- fourier-transform infrared spectroscopy. Further, the size, charge, and polydispersity nature of AgNPs were studied using dynamic light scattering spectroscopy. The morphology of the nanoparticles was determined by scanning electron microscopy. Current result shows core involvement of plant extracts containing glycosides, flavonoids, and phenolic compounds played a crucial role in the biosynthesis of AgNPs. The antimicrobial activities of silver nanoparticles were evaluated against different pathogenic bacterium and fungi. The antioxidant property was studied by radical scavenging (DPPH) assay and cytotoxic activity was evaluated against A-431 osteosarcoma cell line by MTT assay. The characteristics of the synthesized silver nanoparticles suggest their application as a potential antimicrobial and anticancer agent. PMID:28367437

  12. 33 CFR 334.770 - Gulf of Mexico and St. Andrew Sound, south of East Bay, Fla., Tyndall Drone Launch Corridor...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Gulf of Mexico and St. Andrew... ARMY, DEPARTMENT OF DEFENSE DANGER ZONE AND RESTRICTED AREA REGULATIONS § 334.770 Gulf of Mexico and St....; restricted area. (a) The area. The waters of the Gulf of Mexico and St. Andrew Sound within an area described...

  13. 33 CFR 334.770 - Gulf of Mexico and St. Andrew Sound, south of East Bay, Fla., Tyndall Drone Launch Corridor...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 3 2014-07-01 2014-07-01 false Gulf of Mexico and St. Andrew... ARMY, DEPARTMENT OF DEFENSE DANGER ZONE AND RESTRICTED AREA REGULATIONS § 334.770 Gulf of Mexico and St....; restricted area. (a) The area. The waters of the Gulf of Mexico and St. Andrew Sound within an area described...

  14. 33 CFR 334.770 - Gulf of Mexico and St. Andrew Sound, south of East Bay, Fla., Tyndall Drone Launch Corridor...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 3 2013-07-01 2013-07-01 false Gulf of Mexico and St. Andrew... ARMY, DEPARTMENT OF DEFENSE DANGER ZONE AND RESTRICTED AREA REGULATIONS § 334.770 Gulf of Mexico and St....; restricted area. (a) The area. The waters of the Gulf of Mexico and St. Andrew Sound within an area described...

  15. 33 CFR 334.770 - Gulf of Mexico and St. Andrew Sound, south of East Bay, Fla., Tyndall Drone Launch Corridor...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 3 2012-07-01 2012-07-01 false Gulf of Mexico and St. Andrew... ARMY, DEPARTMENT OF DEFENSE DANGER ZONE AND RESTRICTED AREA REGULATIONS § 334.770 Gulf of Mexico and St....; restricted area. (a) The area. The waters of the Gulf of Mexico and St. Andrew Sound within an area described...

  16. 33 CFR 334.770 - Gulf of Mexico and St. Andrew Sound, south of East Bay, Fla., Tyndall Drone Launch Corridor...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Gulf of Mexico and St. Andrew... ARMY, DEPARTMENT OF DEFENSE DANGER ZONE AND RESTRICTED AREA REGULATIONS § 334.770 Gulf of Mexico and St....; restricted area. (a) The area. The waters of the Gulf of Mexico and St. Andrew Sound within an area described...

  17. Traversing the Gap: Andrew Wright, John Hick and Critical Religious Education

    ERIC Educational Resources Information Center

    Teece, Geoff

    2005-01-01

    This paper discusses aspects of Andrew Wright's version of a liberal, critical religious education and his criticisms of some other views of modern religious education. This is attempted not by examining these "other views" as such but by concentrating on the work of John Hick. The reason for this is that Wright, like Cooling (in his…

  18. 16. View of Andrew McLean Company Textile Mill looking southeast; ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. View of Andrew McLean Company Textile Mill looking southeast; Building No. 6 at center, roof of Building No. 1 at left - Dundee Canal Industrial Historic District, Beginning at George Street in Passaic & extending north along Dundee Canal approximately 1.2 miles to Canal headgates opposite East Clifton Avenue in Clifton, Passaic, Passaic County, NJ

  19. 14. View of Andrew McLean Company Textile Mill looking north; ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. View of Andrew McLean Company Textile Mill looking north; Building No. 6 at right, Building No. 1 in background, gateposts in foreground - Dundee Canal Industrial Historic District, Beginning at George Street in Passaic & extending north along Dundee Canal approximately 1.2 miles to Canal headgates opposite East Clifton Avenue in Clifton, Passaic, Passaic County, NJ

  20. 19. View of Andrew McLean Company Textile Mill looking south; ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. View of Andrew McLean Company Textile Mill looking south; Building No. 2 at center, Botany Mills Lanolin Retrieval plant site in foreground - Dundee Canal Industrial Historic District, Beginning at George Street in Passaic & extending north along Dundee Canal approximately 1.2 miles to Canal headgates opposite East Clifton Avenue in Clifton, Passaic, Passaic County, NJ

  1. Antioxidant, Antimicrobial and Cytotoxic Properties as Well as the Phenolic Content of the Extract from Hancornia speciosa Gomes

    PubMed Central

    Santos, Uilson P.; Campos, Jaqueline F.; Torquato, Heron Fernandes V.; Paredes-Gamero, Edgar Julian; Carollo, Carlos Alexandre; Estevinho, Leticia M.; de Picoli Souza, Kely

    2016-01-01

    Hancornia speciosa Gomes (Apocynaceae) is a fruit tree, popularly known as mangabeira, and it is widely distributed throughout Brazil. Several parts of the plant are used in folk medicine, and the leaf and bark extracts have anti-inflammatory, antihypertensive, antidiabetic, and antimicrobial properties. In this study, we investigated the chemical composition of the ethanolic extract of Hancornia speciosa leaves (EEHS) and its antioxidant, antimicrobial, and cytotoxic activities as well as the mechanisms involved in cell death. The chemical compounds were identified by liquid chromatography coupled to mass spectrometry (LC-MS/MS). The antioxidant activity of the EEHS was investigated using the method that involves the scavenging of 2,2-diphenyl-1-picrylhydrazyl free radicals as well as the inhibition of oxidative hemolysis and lipid peroxidation induced by 2,2’-azobis (2-amidinopropane) in human erythrocytes. The antimicrobial activity was determined by calculating the minimum inhibitory concentration, minimum bactericidal concentration, minimum fungicidal concentration, and zone of inhibition. Kasumi-1 leukemic cells were used to assess the cytotoxic activity and mechanisms involved in cell death promoted by the EEHS. The chemical compounds identified were quinic acid, chlorogenic acid, catechin, rutin, isoquercitrin, kaempferol-rutinoside, and catechin-pentoside. The EEHS demonstrated antioxidant activity via the sequestration of free radicals, inhibition of hemolysis, and inhibition of lipid peroxidation in human erythrocytes incubated with an oxidizing agent. The antimicrobial activity was observed against American Type Culture Collection (ATCC) and hospital strains of bacteria and fungi, filamentous fungi and dermatophytes. The cytotoxic activity of the EEHS was induced by apoptosis, reduction of the mitochondrial membrane potential, and activation of cathepsins. Together, these results indicate the presence of phenolic compounds and flavonoids in the EEHS

  2. Analyzing after-action reports from Hurricanes Andrew and Katrina: repeated, modified, and newly created recommendations.

    PubMed

    Knox, Claire Connolly

    2013-01-01

    Thirteen years after Hurricane Andrew struck Homestead, FL, Hurricane Katrina devastated the Gulf Coast of Mississippi, Alabama, and southeastern Louisiana. Along with all its destruction, the term "catastrophic" was redefined. This article extends the literature on these hurricanes by providing a macrolevel analysis of The Governor's Disaster Planning and Response Review Committee Final Report from Hurricane Andrew and three federal after-action reports from Hurricane Katrina, as well as a cursory review of relevant literature. Results provide evidence that previous lessons have not been learned or institutionalized with many recommendations being repeated or modified. This article concludes with a discussion of these lessons, as well as new issues arising during Hurricane Katrina.

  3. A δ(15)N assessment of nitrogen deposition for the endangered epiphytic orchid Laelia speciosa from a city and an oak forest in Mexico.

    PubMed

    Díaz-Álvarez, Edison A; Reyes-García, Casandra; de la Barrera, Erick

    2016-09-01

    Atmospheric nitrogen deposition poses a major threat to global biodiversity. Tropical epiphytic plants are especially at risk given their reliance on atmospheric sources of nutrients. The leaf, pseudobulb, and root carbon and nitrogen content, C:N ratio, as well as the nitrogen isotopic composition were studied for individuals of Laelia speciosa from a city and from an oak forest in Mexico. The nitrogen content of leaves was similar between the city and the oak forest, reaching 1.3 ± 0.2 % (dry mass). The δ(15)N of leaves, pseudobulbs, and roots reached 5.6 ± 0.2 ‰ in the city, values found in sites exposed to industrial and vehicular activities. The δ(15)N for plant from the oak forest amounted to -3.1 ± 0.3 ‰, which is similar to values measured from sites with low industrial activities. Some orchids such as Laelia speciosa produce a single pseudobulb per year, i.e., a water and nutrient storage organ, so the interannual nitrogen deposition was studied by considering the ten most recent pseudobulbs for plants from either site formed between 2003 and 2012. The C:N ratio of the ten most recent pseudobulbs from the oak forest, as well as that of the pseudobulbs formed before 2010 for plants in the city were indistinguishable from each other, averaging 132.4 ± 6.5, while it was lower for the two most recent pseudobulbs in the city. The δ(15)N values of pseudobulbs from the oak forest averaged ‒4.4 ± 0.1 ‰ for the entire series. The δ(15)N ranged from 0.1 ± 1.6 ‰ for the oldest pseudobulb to 4.7 ± 0.2 ‰ for the pseudobulb formed in the city from 2008 onwards. Isotopic analysis and the C:N ratio for L. speciosa revealed that rates of nitrogen deposition were higher in the city than in the forest. The δ(15)N values of series of pseudobulbs showed that it is possible to track nitrogen deposition over multiple years.

  4. 18. View of Andrew McLean Company Textile Mill looking north; ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. View of Andrew McLean Company Textile Mill looking north; Building No. 3 at center right, Building No. 2 at center distance, Dundee Canal at left - Dundee Canal Industrial Historic District, Beginning at George Street in Passaic & extending north along Dundee Canal approximately 1.2 miles to Canal headgates opposite East Clifton Avenue in Clifton, Passaic, Passaic County, NJ

  5. Dr. Andrew Foster: A Literature Review.

    PubMed

    Runnels, Joel

    2017-01-01

    Often compared to Laurent Clerc, Thomas Gallaudet, and Alexander Graham Bell, Dr. Andrew Foster was a deaf African American who founded 32 schools for the deaf in 13 African nations. The 60th anniversary of his arrival in Liberia and Ghana and the 30th anniversary of his tragic death in a Rwanda airplane accident both occur in 2017. Renewed interest in Foster has spawned research and events to reexamine questions about his contributions to the expansion of deaf education in Africa. However, none of these activities have taken a full biographical approach. More in-depth, historical, and biographical research is needed to answer the many remaining questions about Foster's life and legacy. A literature review was conducted to investigate what are considered Foster's key contributions and the factors that might have motivated him to expand access to deaf education in Africa.

  6. James Gregory, the University observatory and the early acquisition of scientific instruments at the University of St Andrews

    PubMed Central

    Rawson, Helen C.

    2015-01-01

    James Gregory, inventor of the reflecting telescope and Fellow of the Royal Society, was the first Regius Professor of Mathematics of the University of St Andrews, 1668–74. He attempted to establish in St Andrews what would, if completed, have been the first purpose-built observatory in the British Isles. He travelled to London in 1673 to purchase instruments for equipping the observatory and improving the teaching and study of natural philosophy and mathematics in the university, seeking the advice of John Flamsteed, later the first Astronomer Royal. This paper considers the observatory initiative and the early acquisition of instruments at the University of St Andrews, with reference to Gregory's correspondence, inventories made ca. 1699–ca. 1718 and extant instruments themselves, some of which predate Gregory's time. It examines the structure and fate of the university observatory, the legacy of Gregory's teaching and endeavours, and the meridian line laid down in 1748 in the University Library.

  7. Ecological evaluation of proposed dredged material from St. Andrew Bay, Florida

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mayhew, H.L.; Word, J.Q.; Kohn, N.P.

    1993-10-01

    The US Army Corps of Engineers (USACE), Mobile District, requested that the Battelle/Marine Sciences Laboratory (MSL) conduct field sampling and chemical and biological testing to determine the suitability of potential dredged material for open ocean disposal. Sediment from St. Andrew Bay was chemically characterized and evaluated for biological toxicity and bioaccumulation of contaminants. The Tier III guidance for ocean disposal testing requires tests of water column effects (following dredged material disposal), deposited sediment toxicity, and bioaccumulation of contaminants from deposited sediment (dredged material). To meet these requirements, the MSL conducted suspended-particulate-phase (SPP) toxicity tests, solid-phase toxicity tests, and bioaccumulation testingmore » on sediment representing potential dredged material from Panama City Harbor. Physical and chemical characterization of sediment to support toxicity and bioaccumulation results was also conducted on both the test and reference sediments. The MSL collected sediment samples from five sites in St. Andrew Bay and one reference site near Lands End Peninsula. The five test sediments and the reference sediment were analyzed for physical and chemical sediment characteristics, SPP chemical contaminants, solid-phase toxicity, SPP toxicity, and bioaccumulation of contaminants.« less

  8. ANDREWS MOUNTAIN, MAZOURKA, AND PAIUTE ROADLESS AREAS, CALIFORNIA.

    USGS Publications Warehouse

    McKee, Edwin H.; Schmauch, Steven W.

    1984-01-01

    On the basis of a mineral survey, local areas near and within the Andrews Mountain, Mazourka, and Paiute Roadless Areas, California have probable and substantiated mineral-resource potential. The principal metallic mineral resources in these roadless areas are gold, copper, and silver with lead, zinc, and tungsten, as lesser resources. A zone of probable resource potential for talc, graphite, and marble is identified in the Mazourka Roadless Area. Metallic mineralization occurs mostly in vein deposits in silicic and carbonate metasedimentary rocks peripheral to Mesozoic plutons and locally in granitic rocks as well. There is little promise for the occurrence of fossil fuel resources in the roadless areas.

  9. Research publications of the H.J. Andrews Experimental Forest, Cascade Range, Oregon: 1988 supplement.

    Treesearch

    T. Blinn; F.J. Swanson; A. McKee

    1988-01-01

    This bibliography updates the list of publications, abstracts, theses, and unpublished reports included in "Research Publications of the H.J. Andrews Experimental Forest, Cascade Range, Oregon, 1948 to 1986," General Technical Report PNW-GTR-201. Citations are referenced under appropriate keywords.

  10. 75 FR 41895 - Whirlpool Corporation, Evansville Division, Including On-Site Leased Workers From Andrews...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-19

    ... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-72,585] Whirlpool Corporation, Evansville Division, Including On-Site Leased Workers From Andrews International, Inc., M.H. Equipment, and Kenco Logistics Services, LLC, Evansville, IN; Amended Certification Regarding Eligibility To Apply for...

  11. Commentary on Andrew Coulson's "Comparing Public, Private, and Market Schools: The International Evidence"

    ERIC Educational Resources Information Center

    Wolfram, Gary; Coulson, Andrew J.

    2009-01-01

    In this article, the authors comment on Andrew Coulson's "Comparing Public, Private, and Market Schools: The International Evidence." The authors believe that Coulson's paper is a very interesting review of the literature on the ability of market-produced education to outperform government-produced education. Coulson's response on this commentary…

  12. Antidiabetes and Anti-obesity Activity of Lagerstroemia speciosa

    PubMed Central

    Klein, Guy; Kim, Jaekyung; Himmeldirk, Klaus; Cao, Yanyan

    2007-01-01

    The leaves of Lagerstroemia speciosa (Lythraceae), a Southeast Asian tree more commonly known as banaba, have been traditionally consumed in various forms by Philippinos for treatment of diabetes and kidney related diseases. In the 1990s, the popularity of this herbal medicine began to attract the attention of scientists worldwide. Since then, researchers have conducted numerous in vitro and in vivo studies that consistently confirmed the antidiabetic activity of banaba. Scientists have identified different components of banaba to be responsible for its activity. Using tumor cells as a cell model, corosolic acid was isolated from the methanol extract of banaba and shown to be an active compound. More recently, a different cell model and the focus on the water soluble fraction of the extract led to the discovery of other compounds. The ellagitannin Lagerstroemin was identified as an effective component of the banaba extract responsible for the activity. In a different approach, using 3T3-L1 adipocytes as a cell model and a glucose uptake assay as the functional screening method, Chen et al. showed that the banaba water extract exhibited an insulin-like glucose transport inducing activity. Coupling HPLC fractionation with a glucose uptake assay, gallotannins were identified in the banaba extract as components responsible for the activity, not corosolic acid. Penta-O-galloyl-glucopyranose (PGG) was identified as the most potent gallotannin. A comparison of published data with results obtained for PGG indicates that PGG has a significantly higher glucose transport stimulatory activity than Lagerstroemin. Chen et al. have also shown that PGG exhibits anti-adipogenic properties in addition to stimulating the glucose uptake in adipocytes. The combination of glucose uptake and anti-adipogenesis activity is not found in the current insulin mimetic drugs and may indicate a great therapeutic potential of PGG. PMID:18227906

  13. 21. View of Andrew McLean Company Textile Mill looking west; ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    21. View of Andrew McLean Company Textile Mill looking west; Building No. 4 at left, Building No. 1 at left center, Building No. 3 at center, Building No. 2 at right center, Building No. 5 at right - Dundee Canal Industrial Historic District, Beginning at George Street in Passaic & extending north along Dundee Canal approximately 1.2 miles to Canal headgates opposite East Clifton Avenue in Clifton, Passaic, Passaic County, NJ

  14. Visions and Vanities: John Andrew Rice of Black Mountain College. Southern Biography Series.

    ERIC Educational Resources Information Center

    Reynolds, Katherine Chaddock

    This biography presents the life of John Andrew Rice, who founded Black Mountain College (North Carolina) in 1933 to implement his philosophy of education, including the centrality of artistic experience and emotional development to learning in all disciplines and the need for democratic governance shared between faculty and students. Born in…

  15. Report: Results of Technical Network Vulnerability Assessment: EPA’s Andrew W. Breidenbach Environmental Research Center

    EPA Pesticide Factsheets

    Report #10-P-0210, September 7, 2010. Vulnerability testing of EPA’s Andrew W. Breidenbach Environmental Research Center network conducted in June 2010 identified Internet Protocol addresses with numerous high-risk and medium-risk vulnerabilities.

  16. STS-89 Mission Specialist Andrew Thomas in White Room

    NASA Technical Reports Server (NTRS)

    1998-01-01

    STS-89 Mission Specialist Andrew Thomas, Ph.D., is assisted with his ascent and re-entry flight suit in the white room at Launch Pad 39A before entering Space Shuttle Endeavour for launch. The STS-89 mission will be the eighth docking of the Space Shuttle with the Russian Space Station Mir. After docking, Thomas will transfer to the space station, succeeding David Wolf, M.D., who will return to Earth aboard Endeavour. Dr. Thomas will live and work on Mir until June. STS-89 is scheduled for a Jan. 22 liftoff at 9:48 p.m.

  17. 77 FR 20621 - Pomperaug Hydro Project; Andrew Peklo III; Notice Extending Deadline for Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-05

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 12790-001] Pomperaug Hydro Project; Andrew Peklo III; Notice Extending Deadline for Comments On January 18, 2012, Office of Energy... the Commission's January 12, 2012, notice, the deadline for filing comments is extended to April 13...

  18. Phenotypic, genetic and symbiotic characterization of Erythrina velutina rhizobia from Caatinga dry forest.

    PubMed

    Rodrigues, Dalila Ribeiro; Silva, Aleksandro Ferreira da; Cavalcanti, Maria Idaline Pessoa; Escobar, Indra Elena Costa; Fraiz, Ana Carla Resende; Ribeiro, Paula Rose de Almeida; Ferreira Neto, Reginaldo Alves; Freitas, Ana Dolores Santiago de; Fernandes-Júnior, Paulo Ivan

    2018-02-02

    Erythrina velutina ("mulungu") is a legume tree from Caatinga that associates with rhizobia but the diversity and symbiotic ability of "mulungu" rhizobia are poorly understood. The aim of this study was to characterize "mulungu" rhizobia from Caatinga. Bacteria were obteined from Serra Talhada and Caruaru in Caatinga under natural regeneration. The bacteria were evaluated to the amplification of nifH and nodC and to metabolic characteristics. Ten selected bacteria identified by 16S rRNA sequences. They were tested in vitro to NaCl and temperature tolerance, auxin production and calcium phosphate solubilization. The symbiotic ability were assessed in an greenhouse experiment. A total of 32 bacteria were obtained and 17 amplified both symbiotic genes. The bacteria showed a high variable metabolic profile. Bradyrhizobium (6), Rhizobium (3) and Paraburkholderia (1) were identified, differing from their geographic origin. The isolates grew up to 45°C to 0.51molL -1 of NaCl. Bacteria which produced more auxin in the medium with l-tryptophan and two Rhizobium and one Bradyrhizobium were phosphate solubilizers. All bacteria nodulated and ESA 90 (Rhizobium sp.) plus ESA 96 (Paraburkholderia sp.) were more efficient symbiotically. Diverse and efficient rhizobia inhabit the soils of Caatinga dry forests, with the bacterial differentiation by the sampling sites. Copyright © 2018 Sociedade Brasileira de Microbiologia. Published by Elsevier Editora Ltda. All rights reserved.

  19. Assessment of gonadotropins and testosterone hormone levels in regular Mitragyna speciosa (Korth.) users.

    PubMed

    Singh, Darshan; Murugaiyah, Vikneswaran; Hamid, Shahrul Bariyah Sahul; Kasinather, Vicknasingam; Chan, Michelle Su Ann; Ho, Eric Tatt Wei; Grundmann, Oliver; Chear, Nelson Jeng Yeou; Mansor, Sharif Mahsufi

    2018-07-15

    Mitragyna speciosa (Korth.) also known as kratom, is a native medicinal plant of Southeast Asia with opioid-like effects. Kratom tea/juice have been traditionally used as a folk remedy and for controlling opiate withdrawal in Malaysia. Long-term opioid use is associated with depletion in testosterone levels. Since kratom is reported to deform sperm morphology and reduce sperm motility, we aimed to clinically investigate the testosterone levels following long-term kratom tea/juice use in regular kratom users. A total of 19 regular kratom users were recruited for this cross-sectional study. A full-blood test was conducted including determination of testosterone level, follicle stimulating hormone (FSH) and luteinizing hormone (LH) profile, as well as hematological and biochemical parameters of participants. We found long-term kratom tea/juice consumption with a daily mitragynine dose of 76.23-94.15 mg did not impair testosterone levels, or gonadotrophins, hematological and biochemical parameters in regular kratom users. Regular kratom tea/juice consumption over prolonged periods (>2 years) was not associated with testosterone impairing effects in humans. Copyright © 2018 Elsevier B.V. All rights reserved.

  20. Long-term experiments on log decomposition at the H.J. Andrews Experimental Forest.

    Treesearch

    M.E. Harmon

    1992-01-01

    A long-term decomposition experiment was established at the H.J. Andrews Experimental Forest, Oregon, during 1985to test the importance of substrate heterogeneity, colonization patterns, and invertebrates on the decomposition of logs. The duration of the study is anticipated to be 200 years. A total of 530 logs (50 centimeters in diameter and 5.5 meters long) were...

  1. STS-89 M.S. Andrew Thomas suits up

    NASA Technical Reports Server (NTRS)

    1998-01-01

    STS-89 Mission Specialist Andrew Thomas, Ph.D., gives a 'thumbs up' as he completes the donning of his launch/entry suit in the Operations and Checkout (O&C) Building. In June 1995, he was named as payload commander for STS-77 and flew his first flight in space on Endeavour in May 1996. He and six fellow crew members will soon depart the O&C and head for Launch Pad 39A, where the Space Shuttle Endeavour will lift off during a launch window that opens at 9:43 p.m. EST, Jan. 22. STS-89 is the eighth of nine planned missions to dock the Space Shuttle with Russia's Mir space station, where Dr. Thomas will succeed David Wolf, M.D.

  2. William Horner Andrews (1887-1953)- first professor of physiology at Onderstepoort.

    PubMed

    Verwoerd, D W; Andrews, W J H

    2011-03-01

    W H Andrews qualified as a veterinarian in London in 1908 and was recruited soon after, in 1909, by Sir Arnold Theiler to join the staff of the newly established veterinary laboratory at Onderstepoort. After initial studies on the treatment of trypanosomosis and on snake venoms he was deployed by Theiler in 1911 to start research on lamsiekte (botulism)at a field station on the farm Kaffraria near Christiana, where he met and married his wife Doris. After a stint as Captain in the SA Veterinary Corps during World War I he succeeded D T Mitchell as head of the Allerton Laboratory in 1918, where he excelled in research on toxic plants, inter alia identifying Matricaria nigellaefolia as the cause of staggers in cattle. When the Faculty of Veterinary Science was established in 1920 he was appointed as the first Professor of Physiology. After the graduation of the first class in 1924, and due to health problems, he returned to the UK, first to the Royal Veterinary College and then to the Weybridge Veterinary Laboratories of which he became Director in 1927. After his retirement in 1947 he returned to South Africa as a guest worker at Onderstepoort where he again became involved in teaching physiology when Prof. Quin unexpectedly died in 1950. Andrews died in Pretoria in 1953 and was buried in the Rebecca Street Cemetery.

  3. Anti–odor activity of milk kefir on organosulphur polysulfide cyclic compounds in petai (parkia speciosa hassk)

    NASA Astrophysics Data System (ADS)

    Kurniati, T.; Windayani, N.; Listiawati, M.

    2018-05-01

    This study aims to assess the activity of milk kefir whey in neutralizing odor-causing cyclic polysulfide compounds in petai (Parkia speciosa Hassk.). RAL designs used to determine the optimum fermentation conditions. The data obtained were processed using SPSS 20. Results showed the characteristics of the microbes in the kefir grains include lactic acid bacteria consisting of genus Lactobacillus and yeast of the genus Candida and Saccharomyces. The optimum fermentation conditions using cow’s milk kefir grain starter obtained in the fermentation time of 24 hours at a concentration of 5% kefir grain. Whey kefir which is produced have high levels of fat, protein, carbohydrates, fiber and lactic acid respectively 1.81; 4.35; 5.59; 0.26 and 0.16%, pH 4.4; a density of 1.0628 g/mL and 7.9368 cP viscosity. Kefir milk whey actively reduced the level of petai smell significantly different at the level of α = 0.05.

  4. Comparative Study of Erythrina indica Lam. (Febaceae) Leaves Extracts for Antioxidant Activity

    PubMed Central

    Sakat, SS; Juvekar, AR

    2010-01-01

    The present study was designed to investigate the antioxidant activity of aqueous and methanol extracts of Erythrina indica Lam leaves by in vitro methods viz. 1, 1-Diphenyl-2-Picrylhydrazyl, nitric oxide radical scavenging activity, and inhibition of lipid peroxidation by thiobarbituric acid reactive substances (TBARS) method on isolated rat liver tissues. Quantitative analysis of antioxidative components like total amount of phenolics, flavonoids, and flavonols were estimated using the spectrophotometric method. Linear regression analysis was used to calculate the IC50 value. Results showed that the aqueous and methanol extracts exhibited significant DPPH radicals scavenging activity with an IC50 value 342.59 ± 19.59, 283.24 ± 12.28 µg/mL respectively. Nitric oxide radicals were significantly scavenged by the aqueous and methanol extracts (IC50 = 250.12 ± 10.66; 328.29 ± 3.74 µg/mL). Lipid peroxidation induced by the Fe2+ was inhibited by the aqueous extract with low IC50 value (97.29 ± 2.05 µg/mL) as compared to methanol extract (IC50 = 283.74 ± 5.70 µg/mL). Both the extracts were exhibited similar quantities of total phenolics. Total flavonoids were found to be in higher quantities than total flavonols in aqueous extract as compared to methanol extract. From the results, it is concluded that the aqueous and methanol extracts of E. indica leaves possesses significant antioxidant activity that may be due to the presence of flavonoids and related polyphenolic compounds. PMID:21331194

  5. PHYSICOCHEMICAL PROPERTIES OF THE PROTEOLYTIC ENZYME FROM THE LATEX OF THE MILKWEED, ASCLEPIAS SPECIOSA TORR. SOME COMPARISONS WITH OTHER PROTEASES

    PubMed Central

    Winnick, Theodore; Davis, Alva R.; Greenberg, David M.

    1940-01-01

    1. The kinetics of milk clotting by asclepain, the protease of Asclepias speciosa, were investigated. At higher concentrations of enzyme, the clotting time was inversely proportional to the enzyme concentration. 2. The digestion of casein and hemoglobin in 6.6 M urea by asclepain follows the second order reaction rate. The rate was roughly second order for casein in water. 3. Evaluation of the nature of the enzyme-substrate intermediate indicates that one molecule of asclepain combines with one molecule of casein or hemoglobin in urea solution. 4. Inhibition by the reaction products was deduced from the fact that the digestion velocity of hemoglobin in urea solution varied with the asclepain concentration in agreement with the Schütz-Borissov rule. PMID:19873155

  6. Research publications of the H.J. Andrews Experimental Forest, Cascade Range, Oregon: 1948 to 1986.

    Treesearch

    A. McKee; G.M. Stonedahl; J.F. Franklin; F.J. Swanson

    1987-01-01

    A list of publications resulting from research at th H.J. Andrews Experimental Forest, Willamette National Forest, Oregon, from 1948 to 1986 is presented. Nearly 600 publications are listed, including papers, theses, and abstracts. An index is provided that cross-references the listings under appropriate keywords.

  7. Development of pile foundation bias factors using observed behavior of platforms during Hurricane Andrew

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aggarwal, R.K.; Litton, R.W.; Cornell, C.A.

    1996-12-31

    The performance of more than 3,000 offshore platforms in the Gulf of Mexico was observed during the passage of Hurricane Andrew in August 1992. This event provided an opportunity to test the procedures used for platform analysis and design. A global bias was inferred for overall platform capacity and loads in the Andrew Joint Industry Project (JIP) Phase 1. It was predicted that the pile foundations of several platforms should have failed, but did not. These results indicated that the biases specific to foundation failure modes may be higher than those of jacket failure modes. The biases in predictions ofmore » foundation failure modes were therefore investigated further in this study. The work included capacity analysis and calibration of predictions with the observed behavior for 3 jacket platforms and 3 caissons using Bayesian updating. Bias factors for two foundation failure modes, lateral shear and overturning, were determined for each structure. Foundation capacity estimates using conventional methods were found to be conservatively biased overall.« less

  8. Astronauts Mario Runco, Jr. and Andrew S. W. Thomas, both mission specialists, pose for photo while

    NASA Technical Reports Server (NTRS)

    1996-01-01

    STS-77 ESC VIEW --- Astronauts Mario Runco, Jr. and Andrew S. W. Thomas, both mission specialists, pose for photo while in the mid-deck of the Earth-orbiting Space Shuttle Endeavour. The scene was recorded with an Electronic Still Camera (ESC).

  9. Impact and hardness optimisation of composite materials inspired by the babassu nut (Orbignya speciosa).

    PubMed

    Staufenberg, Gerrit; Graupner, Nina; Müssig, Jörg

    2015-08-20

    The babassu nut is the fruit of the babassu palm Orbignya speciosa. The combination of hardness and impact strength is difficult to acquire for artificial materials, making the babassu nut a promising source for biomimetic inspiration. Unnotched Charpy impact tests, Shore D hardness tests and scanning electron microscopy were used for mechanical and microscopical analysis of the pericarp. Four major principles were found for a biomimetic approach: a hard core ((1); endocarp) is embedded in a soft outer layer of high impact strength ((2); epicarp) and is reinforced with fibres of variable fineness (3), some of which are oriented radial to the core (4). Biomimetic fibre-reinforced composites were produced using abstracted mechanisms of the babassu nut based on regenerated cellulose fibres (lyocell, L) with two different fineness values as reinforcement embedded in a polylactide (PLA) core matrix and polypropylene (PP) based outer layers. The biomimetic fibre composite reaches a significantly higher impact strength that is 1.6 times higher than the reference sample produced from a PLA/PP/L-blend. At the same time the hardness is slightly increased compared to PP/L.

  10. Development of ultrasonic-assisted extraction of antioxidant compounds from Petai (Parkia speciosa Hassk.) leaves

    NASA Astrophysics Data System (ADS)

    Buanasari; Palupi, P. D.; Serang, Y.; Pramudono, B.; Sumardiono, S.

    2018-04-01

    Research on Petai (Parkia speciosa Hassk.) suggests it has an antihypertension, antidiabetic, analgesic, and antiulcer effects. In the present study, an ultrasonic-assisted extraction method was developed for the effective extraction of active compound from petai leaves. Some parameters such as ethanol concentration (0, 20, 40, 60, 70, 80, 100 %v), solid-to-liquid ratio (1:5; 1:10; 1:15; 1:20; 1:25; 1:30; 1:35; 1:40; 1:50 g/mL), extraction time (15, 20, 25, 30, 35, 40, 50 minutes) and extraction temperature (40, 45, 50, 55, 60, 65, 70°C) were studied and evaluated base on extract yield and 1,1-diphenyl-2-picry hydrazyl (DPPH) scavenging activity. The result showed that the highest extract yield was obtained at 40% ethanol concentration, 1:30 (%w/v) of solid-to-liquid ratio, 30 minutes and 65°C of temperature with DPPH scavenging activity 92.53 ± 0.87% and extract yield 21.25 ± 2.38%. The result obtained is helpful for the utilization of Petai leaves, and also indicated that ultrasonic-assisted extraction is a very recommended method for the extraction of active compounds from plant material.

  11. Food-related coping strategies after Hurricane Andrew.

    PubMed

    Magnus, M H

    1994-06-01

    This telephone survey examined food-related coping strategies in Floridian households after Hurricane Andrew. Approximately 137 households of university faculty and staff who lived in hurricane-damaged areas were interviewed. The average respondent was a college-educated woman between 41 and 60 years old. Prevailing food-purchasing problems included food stores that were either closed, without perishable food, distant, or crowded. In the absence of electricity and water, changes in food preparation included preparation of meals without a stove, more frequent use of grills and canned food, simpler meals, and less cooking. Changes in kitchen cleanup included using more disposables, cleaning more often, washing dishes by hand, and cleaning up less often because of damage in the kitchen. Respondents indicated that the hurricane experience taught them that they should have acquired more general supplies (eg, coolers, thermoses, propane stoves, and gas burners), more water and ice, and more nonperishable foods before the hurricane.

  12. STS-75 Mission Cmdr Andrew Allen inspects SPREE in O&C

    NASA Technical Reports Server (NTRS)

    1995-01-01

    STS-75 Mission Commander Andrew Allen inspects the Shuttle Potential and Return Experiment (SPRE) that will fly on his mission in the Operations and Checkout (O&C) Building. This 14- day mission is now scheduled for early 1996 aboard the Space Shuttle Orbiter Columbia. The primary payloads are the Tethered Satellite System-1R (TSS-1R) and the U.S. Microgravity Payload-3 (USMP-3). The 'R' designation indicates a reflight of the TSS-1. It originally flew on STS-46 in July 1992 but achieved only partial success.

  13. Deaths related to Hurricane Andrew in Florida and Louisiana, 1992.

    PubMed

    Combs, D L; Parrish, R G; McNabb, S J; Davis, J H

    1996-06-01

    Information about circumstances leading to disaster-related deaths helps emergency response coordinators and other public health officials respond to the needs of disaster victims and develop policies for reducing the mortality and morbidity of future disasters. In this paper, we describe the decedent population, circumstances of death, and population-based mortality rates related to Hurricane Andrew, and propose recommendations for evaluating and reducing the public health impact of natural disasters. To ascertain the number and circumstances of deaths attributed to Hurricane Andrew in Florida and Louisiana, we contacted medical examiners in 11 Florida counties and coroners in 36 Louisiana parishes. In Florida medical examiners attributed 44 deaths to the hurricane. The mortality rate for directly-related deaths was 4.4 per 1 000 000 population and that for indirectly-related deaths was 8.5 per 1 000 000 population. In Louisiana, coroners attributed 11 resident deaths to the hurricane. Mortality rates were 0.6 per 1000 000 population for deaths directly related to the storm and 2.8 for deaths indirectly related to the storm. Six additional deaths occurred among non-residents who drowned in international waters in the Gulf of Mexico. In both Florida and Louisiana, mortality rates generally increased with age and were higher among whites and males. In addition to encouraging people to follow existing recommendations, we recommend emphasizing safe driving practices during evacuation and clean-up, equipping shelters with basic medical needs for the population served, and modifying zoning and housing legislation. We also recommend developing and using a standard definition for disaster-related deaths, and using population-based statistics to describe the public health effectiveness of policies intended to reduce disaster-related mortality.

  14. Antibacterial and cytotoxic effect of biologically synthesized silver nanoparticles using aqueous root extract of Erythrina indica lam

    NASA Astrophysics Data System (ADS)

    Rathi Sre, P. R.; Reka, M.; Poovazhagi, R.; Arul Kumar, M.; Murugesan, K.

    2015-01-01

    Simple, yet an effective and rapid approach for the green synthesis of silver nanoparticles (Ag NPs) using root extract of Erythrina indica and its in vitro antibacterial activity was tried against human pathogenic bacteria and its cytotoxic effect in breast and lung cancer cell lines has been demonstrated in this study. Various instrumental techniques were adopted to characterize the synthesized Ag NPs viz. UV-Vis (Ultra violet), FTIR (Fourier Transform Infrared), XRD (X-ray diffraction), DLS (Dynamic light scattering), HR TEM (High-resolution transmission electron microscopy), EDX (Energy-dispersive X-ray spectroscopy). Surface plasmon spectra for Ag NPs are centered nearly at 438 nm with dark brown color. FTIR analysis revealed the presence of terpenes, phenol, flavonols and tannin act as effective reducing and capping agents for converting silver nitrate to Ag NPs. The synthesized Ag NPs were found to be spherical in shape with size in the range of 20-118 nm. Moreover, the synthesized Ag NPs showed potent antibacterial activity against Gram positive and Gram negative bacteria and these biologically synthesized nanoparticles were also proved to exhibit excellent cytotoxic effect on breast and lung cancer cell lines.

  15. STS-89 Mission Specialist Andrew Thomas arrives for TCDT

    NASA Technical Reports Server (NTRS)

    1998-01-01

    STS-89 Mission Specialist Andrew Thomas, Ph.D., poses in his T-38 jet trainer after landing with other members of the flight crew at KSCs Shuttle Landing Facility from NASAs Johnson Space Center to begin Terminal Countdown Demonstration Test (TCDT) activities. The TCDT is held at KSC prior to each Space Shuttle flight to provide crews with the opportunity to participate in simulated countdown activities. Endeavour is targeted for launch of STS-89 on Jan. 22 at 9:48 p.m. EST., which will be the first mission of 1998 and the eighth to dock with Russias Mir Space Station, where Thomas will succeed David Wolf, M.D., who has been on Mir since September 28. The STS-89 mission is scheduled to last nine days.

  16. Antioxidant and anti-inflammatory activities of extracts from Cassia alata, Eleusine indica, Eremomastax speciosa, Carica papaya and Polyscias fulva medicinal plants collected in Cameroon.

    PubMed

    Sagnia, Bertrand; Fedeli, Donatella; Casetti, Rita; Montesano, Carla; Falcioni, Giancarlo; Colizzi, Vittorio

    2014-01-01

    The vast majority of the population around the world has always used medicinal plants as first source of health care to fight infectious and non infectious diseases. Most of these medicinal plants may have scientific evidence to be considered in general practice. The aim of this work was to investigate the antioxidant capacities and anti-inflammatory activities of ethanol extracts of leaves of Cassia alata, Eleusine indica, Carica papaya, Eremomastax speciosa and the stem bark of Polyscias fulva, collected in Cameroon. Chemiluminescence was used to analyze the antioxidant activities of plant extracts against hydrogen peroxide or superoxide anion. Comet assays were used to analyze the protection against antioxidant-induced DNA damage induced in white blood cells after treating with hydrogen peroxide. Flow cytometry was used to measure γδ T cells proliferation and anti-inflammatory activity of γδ T cells and of immature dendritic cells (imDC) in the presence of different concentrations of plant extracts. Ethanol extracts showed strong antioxidant properties against both hydrogen peroxide and superoxide anion. Cassia alata showed the highest antioxidant activity. The effect of plant extracts on γδ T cells and imDC was evidenced by the dose dependent reduction in TNF-α production in the presence of Cassia alata, Carica papaya, Eremomastax speciosa Eleusine indica, and Polyscias fulva. γδ T cells proliferation was affected to the greatest extent by Polyscias fulva. These results clearly show the antioxidant capacity and anti-inflammatory activities of plant extracts collected in Cameroon. These properties of leaves and stem bark extracts may contribute to the value for these plants in traditional medicine and in general medical practice.

  17. Antioxidant and Anti-Inflammatory Activities of Extracts from Cassia alata, Eleusine indica, Eremomastax speciosa, Carica papaya and Polyscias fulva Medicinal Plants Collected in Cameroon

    PubMed Central

    Sagnia, Bertrand; Fedeli, Donatella; Casetti, Rita; Montesano, Carla; Falcioni, Giancarlo; Colizzi, Vittorio

    2014-01-01

    Background The vast majority of the population around the world has always used medicinal plants as first source of health care to fight infectious and non infectious diseases. Most of these medicinal plants may have scientific evidence to be considered in general practice. Objective The aim of this work was to investigate the antioxidant capacities and anti-inflammatory activities of ethanol extracts of leaves of Cassia alata, Eleusine indica, Carica papaya, Eremomastax speciosa and the stem bark of Polyscias fulva, collected in Cameroon. Methods Chemiluminescence was used to analyze the antioxidant activities of plant extracts against hydrogen peroxide or superoxide anion. Comet assays were used to analyze the protection against antioxidant-induced DNA damage induced in white blood cells after treating with hydrogen peroxide. Flow cytometry was used to measure γδ T cells proliferation and anti-inflammatory activity of γδ T cells and of immature dendritic cells (imDC) in the presence of different concentrations of plant extracts. Results Ethanol extracts showed strong antioxidant properties against both hydrogen peroxide and superoxide anion. Cassia alata showed the highest antioxidant activity. The effect of plant extracts on γδ T cells and imDC was evidenced by the dose dependent reduction in TNF-α production in the presence of Cassia alata, Carica papaya, Eremomastax speciosa Eleusine indica, and Polyscias fulva. γδ T cells proliferation was affected to the greatest extent by Polyscias fulva. Conclusion These results clearly show the antioxidant capacity and anti-inflammatory activities of plant extracts collected in Cameroon. These properties of leaves and stem bark extracts may contribute to the value for these plants in traditional medicine and in general medical practice. PMID:25090613

  18. Kratom (Mitragyna speciosa) dependence, withdrawal symptoms and craving in regular users.

    PubMed

    Singh, Darshan; Müller, Christian P; Vicknasingam, Balasingam K

    2014-06-01

    Kratom (Mitragyna speciosa) preparations have been traditionally used in Southeast Asia for its medicinal properties. Lately, Kratom use has spread to Europe and the US, where abuse potential and health hazards increasingly emerge. This study is the first to measure systematically Kratom dependence, withdrawal symptoms, and drug craving in regular Kratom users in Malaysia. A cross-sectional survey of 293 regular Kratom users was conducted in the community across three northern peninsular states of Malaysia. The Leeds Dependence Questionnaire, Marijuana Withdrawal Checklist, and Marijuana Craving Questionnaire-Short Form were used to measure Kratom dependence, withdrawal and craving. More than half of the regular users (>6 month of use) developed severe Kratom dependence problems, while 45% showed a moderate Kratom dependence. Physical withdrawal symptoms commonly experienced include muscle spasms and pain, sleeping difficulty, watery eyes/nose, hot flashes, fever, decreased appetite, and diarrhoea. Psychological withdrawal symptoms commonly reported were restlessness, tension, anger, sadness, and nervousness. The average amount of the psychoactive compound, mitragynine, in a single dose of a Kratom drink was 79mg, suggesting an average daily intake of 276.5mg. Regular users who consumed ≥3 glasses Kratom per day, had higher odds of developing severe Kratom dependence, withdrawal symptoms, and inability to control Kratom craving. The findings from this study show that regular Kratom use is associated with drug dependency, development of withdrawal symptoms, and craving. These symptoms become more severe with prolonged use and suggest a stronger control of the drug. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  19. Airborne Videography and GPS for Assessment of Forest Damage in Southern Louisiana from Hurricane Andrew

    Treesearch

    D.M. Jacobs; Susan Eggen-McIntosh

    1993-01-01

    Abstract: One week after Hurricane Andrew made landfall in Louisiana in August 1992, an airborne videography system, with a global positioning system (GPS) receiver, was used to assess timberland damage across a 1.7 million-ha (4.2 million-acre) study area. Ground observations were made to identify different intensities of timber damage and then...

  20. Sleep disturbance and its relationship to psychiatric morbidity after Hurricane Andrew.

    PubMed

    Mellman, T A; David, D; Kulick-Bell, R; Hebding, J; Nolan, B

    1995-11-01

    Sleep disturbance is an important dimension of posttraumatic stress disorder (PTSD), but most of the limited available data were obtained years after the original traumatic event. This study provides information on sleep disturbance and its relationship to posttraumatic morbidity from evaluations done within a year after the trauma. Sleep and psychiatric symptoms of 54 victims (12 men and 42 women) of Hurricane Andrew who had no psychiatric illness in the 6 months before the hurricane were evaluated. A subset of hurricane victims with active psychiatric morbidity (N = 10) and nine comparison subjects who were unaffected by the hurricane were examined in a sleep laboratory. A broad range of sleep-related complaints were rated as being greater after the hurricane, and psychiatric morbidity (which was most commonly PTSD, followed by depression) had a significant effect on most of the subjective sleep measures. In addition, subjects with active morbidity endorsed greater frequencies of "bad dreams" and general sleep disturbances before the hurricane. Polysomnographic results for the hurricane victims revealed a greater number of arousals and entries into stage 1 sleep. REM density correlated positively with both the PTSD symptom of reexperiencing trauma and global distress. Subjects affected by Hurricane Andrew reported sleep disturbances, particularly those subjects with psychiatric morbidity. Tendencies to experience bad dreams and interrupted sleep before a trauma appear to mark vulnerability to posttraumatic morbidity. Results of sleep laboratory evaluations suggested brief shifts toward higher arousal levels during sleep for PTSD subjects and a relationship of REM phasic activity and symptom severity.

  1. 76 FR 79675 - Pomperaug Hydro Project Andrew Peklo III; Notice of Site Visit and Technical Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-22

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 12790-001] Pomperaug Hydro Project Andrew Peklo III; Notice of Site Visit and Technical Meeting On January 18, 2012, Office of Energy Projects staff will hold a site visit and technical meeting for the proposed Pomperaug Hydro Project (FERC...

  2. Astronaut Andrew M. Allen, mission commander, sets up systems for a television downlink on the

    NASA Technical Reports Server (NTRS)

    1996-01-01

    STS-75 ONBOARD VIEW --- Astronaut Andrew M. Allen, mission commander, sets up systems for a television downlink on the flight deck of the Space Shuttle Columbia. Allen was joined by four other astronauts and an international payload specialist for more than 16 days of research aboard Columbia. The photograph was taken with a 70mm handheld camera.

  3. Response to Paper III Economics in the Civics Curriculum. A Reaction to Andrew F. Brimmer.

    ERIC Educational Resources Information Center

    Schug, Mark C.

    According to the document, Dr. Andrew Brimmer did an excellent job of identifying emerging economic concerns. Dr. Brimmer's characterization of economics as a tool kit can help young people examine important social questions using principles of economics as the tool for analysis. One way to build an economics tool kit is by placing more stress on…

  4. Micropropagation and in vitro conservation of vanilla (Vanilla planifolia Andrews).

    PubMed

    Divakaran, Minoo; Babu, K Nirmal

    2009-01-01

    Vanilla (Vanilla planifolia Andrews (syn. V. fragrans Salisb.), a source of natural vanillin, plays a major positive role in the economy of several countries. A native to the Central America, its primary gene pool is threatened by deforestation and over collection that has resulted in disappearance of natural habitats and wild species. Therefore, multiplication and conservation of vanilla diversity is of paramount importance because of its narrow genetic base. It plays an important role in the production of disease free planting material for commercial cultivation. Simple protocols for micropropagation, in vitro conservation and synthetic seed production are described in this chapter which could further be applied to other related vanilla species as well.

  5. In vitro and ex vivo anticholinesterase activities of Erythrina velutina leaf extracts.

    PubMed

    Santos, Wanderson Praxedes; da Silva Carvalho, Ana Carla; dos Santos Estevam, Charles; Santana, Antônio Euzébio Goulart; Marçal, Rosilene Moretti

    2012-07-01

    Erythrina velutina (EV) Willd (Fabaceae-Faboideae) is a medicinal tree that is commonly used in Brazil for the treatment of several central nervous system disorders. The anticholinesterase activity of EV is described in this work. Concentration-response curves (0-1.6 mg/mL) for EV leaf aqueous extract (AE) and alkaloid-rich extracts (AKEs) were performed in vitro. Cholinesterase inhibition was examined in mouse brains, as the cholinesterase source, and in pure acetylcholinesterase (AChE) or butyrylcholinesterase (BuChE). Mice were treated with AE or AKE (100, 200, and 400 mg/kg, p.o.) and their brains were used for the measurement of cholinesterase activity (CA) ex vivo. CA was inhibited by AE (IC(50) = 0.57 [0.43-0.75] mg/mL) and AKE (IC(50) = 0.52 [0.39-0.70] mg/mL) in brain homogenates in a concentration-dependent manner. The ex vivo experiments indicated that AE (400 mg/kg, p < 0.05, 32.2 ± 3.9% of inhibition) and AKE (all doses: p < 0.05-p < 0.001, 29.6 ± 3.2% as the maximum inhibition) significantly inhibited CA in the central nervous system after oral administration. AE and AKE inhibited AChE and BuChE activities in a concentration-dependent manner (AE: IC(50AChE) = 0.56 [0.38-0.81] mg/mL, IC(50BuChE) = 2.95 [1.51-5.76] mg/mL, AKE: IC(50AChE) = 0.87 [0.60-12.5] mg/mL, IC(50BuChE) = 2.67 [0.87-8.11] mg/mL). These data indicated that AE and AKE crossed the blood-brain barrier to inhibit CA in the brain. AE and AKE also exhibited a dual inhibitory action on acetyl- and BuChE.

  6. 77 FR 2968 - Pomperaug Hydro Project, Andrew Peklo III; Notice Establishing Deadline for Comments and Reply...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-20

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 12790-001] Pomperaug Hydro Project, Andrew Peklo III; Notice Establishing Deadline for Comments and Reply Comments On December 15, 2011, the Commission issued notice that Office of Energy Projects staff will hold a site visit and technical meeting on January 18, 2012. The...

  7. Delayed tree mortality in the Atchafalaya Basin of Southern Louisiana following Hurricane Andrew

    USGS Publications Warehouse

    Keeland, B.D.; Gorham, L.E.

    2009-01-01

    Hurricanes can damage trees in forested wetlands, and the potential for mortality related to these storms exists due to the effects of tree damage over time. In August 1992, Hurricane Andrew passed through the forested wetlands of southern Louisiana with winds in excess of 225 kph. Although more than 78 of the basal area was destroyed in some areas, most trees greater than 2.5 cm dbh were alive and resprouting prolifically the following year (98.8). Survival of most tree species was similarly high two years after the hurricane, but mortality rates of some species increased dramatically. For example, Populus heterophylla (swamp cottonwood) mortality increased from 7.8 to 59.2 (n 76) and Salix interior (sandbar willow) mortality increased from 4.5 to 57.1 (n 21). Stem sprouts on many up-rooted hardwood trees of other species were still alive in 1998, 6 years after the hurricane. Due to the understory tree species composition, regeneration, and high levels of resprouting, there was little change in species composition or perhaps a slight shift toward more shade and flood tolerant species six years following the hurricane event. Triadica sebifera (Chinese tallow) was found on some of the sites heavily disturbed by Hurricane Andrew, and may proliferate at the expense of native tree species. ?? 2009 The Society of Wetland Scientists.

  8. Discriminative validity of the MacAndrew Alcoholism Scale with Cluster B personality disorders.

    PubMed

    Smith, S R; Hilsenroth, M J

    2001-06-01

    This study was designed to assess the ability of the Minnesota Multiphasic Personality Inventory (MMPI-2) MacAndrew Alcoholism Scale (MAC-R) to differentiate between outpatients with personality disorders with Substance-Related Disorders (SRDs) and without SRDs. MMPI-2 validity, clinical, and MAC-R scale scores were compared in an SRD Cluster B group (comprised of Narcissistic, Antisocial, Borderline, and Histrionic; n = 15), a non-SRD Cluster B group (n = 33), and a non-SRD group with personality disorders from Clusters A and C (n = 18). Results revealed that the substance-abusing Cluster B group scored significantly higher on the MAC-R ( p <.0001) as well as the Psychopathic Deviate scale ( p <.01). Dimensional analyses illustrated that MAC-R scores were related to the presence of an SRD diagnosis (rpb =.70, p <.0001) and diagnostic criteria for Antisocial Personality Disorder (r =.60, p <.0001). Stepwise regression revealed that (in order of magnitude) the presence of a substance-abuse diagnosis followed by diagnostic criteria for Antisocial and Histrionic Personality Disorders were most related to MAC-R scores (R =.78, R(2) =.60). This indicates that the MAC-R may be more related to the presence of an SRD than has been suggested, and when used in outpatient settings as MacAndrew (1965) intended, the MAC-R may be useful as a screening device for assessing SRD among outpatients with Axis II psychopathology.

  9. Evaluation of long-term community recovery from Hurricane Andrew: sources of assistance received by population sub-groups.

    PubMed

    McDonnell, S; Troiano, R P; Barker, N; Noji, E; Hlady, W G; Hopkins, R

    1995-12-01

    Two three-stage cluster surveys were conducted in South Dade County, Florida, 14 months apart, to assess recovery following Hurricane Andrew. Response rates were 75 per cent and 84 per cent. Sources of assistance used in recovery from Hurricane Andrew differed according to race, per capita income, ethnicity, and education. Reports of improved living situation post-hurricane were not associated with receiving relief assistance, but reports of a worse situation were associated with loss of income, being exploited, or job loss. The number of households reporting problems with crime and community violence doubled between the two surveys. Disaster relief efforts had less impact on subjective long-term recovery than did job or income loss or housing repair difficulties. Existing sources of assistance were used more often than specific post-hurricane relief resources. The demographic make-up of a community may determine which are the most effective means to inform them after a disaster and what sources of assistance may be useful.

  10. Overexpression of the cucumber LEAFY homolog CFL and hormone treatments alter flower development in gloxinia (Sinningia speciosa).

    PubMed

    Zhang, Ming-Zhe; Ye, Dan; Wang, Li-Lin; Pang, Ji-Liang; Zhang, Yu-Hong; Zheng, Ke; Bian, Hong-Wu; Han, Ning; Pan, Jian-Wei; Wang, Jun-Hui; Zhu, Mu-Yuan

    2008-07-01

    Leafy (LFY) and LFY-like genes control the initiation of floral meristems and regulate MADS-box genes in higher plants. The Cucumber-FLO-LFY (CFL) gene, a LFY homolog in Cucumis sativus L. is expressed in the primordia, floral primordia, and each whirl of floral organs during the early stage of flower development. In this study, functions of CFL in flower development were investigated by overexpressing the CFL gene in gloxinia (Sinningia speciosa). Our results show that constitutive CFL overexpression significantly promote early flowering without gibberellin (GA(3)) supplement, suggesting that CFL can serve functionally as a LFY homolog in gloxinia. Moreover, GA(3) and abscisic acid (ABA) treatments could modulate the expression of MADS-box genes in opposite directions. GA(3) resembles the overexpression of CFL in the expression of MADS-box genes and the regeneration of floral buds, but ABA inhibits the expression of MADS-box genes and flower development. These results suggest that CFL and downstream MADS-box genes involved in flower development are regulated by GA(3) and ABA.

  11. Astronaut Andrew S. W. Thomas, mission specialist, is helped with the final touches of suit donning

    NASA Technical Reports Server (NTRS)

    1996-01-01

    STS-77 TRAINING VIEW --- Astronaut Andrew S. W. Thomas, mission specialist, is helped with the final touches of suit donning during emergency bailout training for crew members in the Johnson Space Centers (JSC) Weightless Environment Training Facility (WET-F). Thomas will join five other astronauts for nine days aboard the Space Shuttle Endeavour next month.

  12. Gastroprotective and antielastase effects of protein inhibitors from Erythrina velutina seeds in an experimental ulcer model.

    PubMed

    Oliveira de Lima, Vanessa Cristina; de Araújo Machado, Richele Janaína; Vieira Monteiro, Norberto Kássio; de Lyra, Ibson Lucas; da Silva Camillo, Christina; Coelho Serquiz, Alexandre; Silva de Oliveira, Adeliana; da Silva Rufino, Fabíola Patrícia; Leal Lima Maciel, Bruna; Ferreira Uchôa, Adriana; Antunes Dos Santos, Elizeu; de Araújo Morais, Ana Heloneida

    2017-04-01

    Trypsin and chymotrypsin inhibitors from Erythrina velutina seeds have been previously isolated by our group. In previous studies using a sepsis model, we demonstrated the antitumor and anti-inflammatory action of these compounds. This study aimed to evaluate the gastroprotective and antielastase effects of protein inhibitors from E. velutina seeds in an experimental stress-induced ulcer model. Two protein isolates from E. velutina seeds, with antitrypsin (PIAT) and antichymotrypsin (PIAQ) activities, were tested. Both protein isolates showed a high affinity and inhibitory effect against human neutrophil elastase, with 84% and 85% inhibition, respectively. Gastric ulcer was induced using ethanol (99%) in 6 groups of animals (female Wistar rats, n = 6). Before ulcer induction, these animals were treated for 5 days with one of the following: (1) PIAT (0.2 mg·kg -1 ), (2) PIAT (0.4 mg·kg -1 ), (3) PIAQ (0.035 mg·kg -1 ), (4) ranitidine hydrochloride (50 mg·kg -1 ), (5) saline solution (0.9%), or (6) no intervention (sham). Both PIAT and PIAQ protected gastric mucosa, preventing hemorrhagic lesions, edema, and mucus loss. No histologic toxic effects of PIAT or PIAQ were seen in liver and pancreatic cells. Our results show that protein isolates from E. velutina seeds have potential gastroprotective effects, placing these compounds as natural candidates for gastric ulcer prevention.

  13. Alkaloids in Erythrina by UPLC-ESI-MS and In Vivo Hypotensive Potential of Extractive Preparations

    PubMed Central

    Merlugo, Liara; Santos, Marí C.; Sant'Anna, Liane S.; Cordeiro, Everson W. F.; Batista, Luiz A. C.; Miotto, Silvia T. S.; Garcia, Cássia V.; Moreira, Cleci M.; Mendez, Andreas S. L.

    2015-01-01

    Erythrina species are used in popular medicine as sedative, anxiolytic, anti-inflammatory, and antihypertensive. In this work, we investigated the chemical composition of extracts obtained from leaves of E. falcata and E. crista-galli. The hypotensive potential of E. falcata and the mechanism of action were also studied. The extracts were obtained by maceration and infusion. The total content of phenolic compounds and flavonoids was estimated by spectrophotometric methods. The chemical constituents were studied performing a chromatographic analysis by UPLC-ESI-MS. For in vivo protocols, blood pressure and heart rate were measured by the invasive hemodynamic monitoring method. Different concentrations of extracts and drugs such as L-NAME, losartan, hexamethonium, and propranolol were administrated i.v. The results of total phenolic contents for E. falcata and E. crista-galli were 1.3193–1.4989 mgGAE/mL for maceration and 0.8771–0.9506 mgGAE/mL for infusion. In total flavonoids, the content was 7.7829–8.1976 mg RE/g for maceration and 9.3471–10.4765 RE mg/g for infusion. The chemical composition was based on alkaloids, suggesting the presence of erythristemine, 11β-methoxyglucoerysodine, erysothiopine, 11β-hydroxyerysodine-glucose, and 11-hydroxyerysotinone-rhamnoside. A potent dose-dependent hypotensive effect was observed for E. falcata, which may be related to the route of β-adrenergic receptors. PMID:26356581

  14. Anti-HIV and cytotoxic biphenyls, benzophenones and xanthones from stems, leaves and twigs of Garcinia speciosa.

    PubMed

    Pailee, Phanruethai; Kuhakarn, Chutima; Sangsuwan, Chanyapat; Hongthong, Sakchai; Piyachaturawat, Pawinee; Suksen, Kanoknetr; Jariyawat, Surawat; Akkarawongsapat, Radeekorn; Limthongkul, Jitra; Napaswad, Chanita; Kongsaeree, Palangpon; Prabpai, Samran; Jaipetch, Thaworn; Pohmakotr, Manat; Tuchinda, Patoomratana; Reutrakul, Vichai

    2018-03-01

    Eleven previously undescribed compounds, including four benzophenones (garciosones A-D), four xanthones (garciosones E-H) and three biphenyls (garciosines A-C), along with eighteen known compounds were isolated from the stems, leaves and twigs of Garcinia speciosa Wall. (Clusiaceae). Their structures were established by extensive spectroscopic analysis. For garciosines A-C, the structures were confirmed by single crystal X-ray diffraction analysis. Most of the isolated compounds were evaluated for their cytotoxic activity and anti-HIV-1 activity using the syncytium inhibition assay and HIV-1 reverse transcriptase (RT) assay. The known compounds, 4,6,3',4'-tetrahydroxy-2-methoxybenzophenone and macluraxanthone, displayed significant cytotoxic activity with the ED 50 in the range of 1.85-11.76 μM. 1,5-Dihydroxyxanthone exhibited the most potent anti-HIV activity against syncytium formation with EC 50  < 17.13 μM (SI > 25.28) and 2-(3,3-dimethylallyl)-1,3,7-trihydroxyxanthone was the most active compound in the HIV-1 reverse transcriptase assay with IC 50 value of 58.24 μM. Structure-activity relationship of some isolated compounds were also discussed. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Invertebrates of The H.J. Andrews Experimental Forest, Western Cascades, Oregon: III. The Orthoptera (Grasshoppers and Crickets).

    Treesearch

    David C. Lightfoot

    1986-01-01

    An inventory of Orthoptera (grasshoppers and crickets) at the H.J. Andrews Experimental Forest, near Blue River, Oregon, was conducted to determine the species present and ecological relationships. A key for identification and an annotated list are presented. From qualitative assessments of successional habitat relationships, generalized species associations of forest...

  16. Remote sensing for hurricane Andrew impact assessment

    NASA Technical Reports Server (NTRS)

    Davis, Bruce A.; Schmidt, Nicholas

    1994-01-01

    Stennis Space Center personnel flew a Learjet equipped with instrumentation designed to acquire imagery in many spectral bands into areas most damaged by Hurricane Andrew. The calibrated airborne multispectral scanner (CAMS), a NASA-developed sensor, and a Zeiss camera acquired images of these areas. The information derived from the imagery was used to assist Florida officials in assessing the devastation caused by the hurricane. The imagery provided the relief teams with an assessment of the debris covering roads and highways so cleanup plans could be prioritized. The imagery also mapped the level of damage in residential and commercial areas of southern Florida and provided maps of beaches and land cover for determination of beach loss and vegetation damage, particularly the mangrove population. Stennis Space Center personnel demonstrated the ability to respond quickly and the value of such response in an emergency situation. The digital imagery from the CAMS can be processed, analyzed, and developed into products for field crews faster than conventional photography. The resulting information is versatile and allows for rapid updating and editing. Stennis Space Center and state officials worked diligently to compile information to complete analyses of the hurricane's impact.

  17. Should Community College Be Free? Forum. "Education Next" Talks with Sara Goldrick-Rab and Andrew P. Kelly

    ERIC Educational Resources Information Center

    Goldrick-Rab, Sara; Kelly, Andrew P.

    2016-01-01

    In this article, "Education Next" talks with Sara Goldrick-Rab and Andrew Kelly. President Obama's proposal for tuition-free community college, seems to have laid down a marker for the Democratic Party. Vermont senator Bernie Sanders is touting his plan for free four-year public college on the primary trail; Massachusetts senator…

  18. Religious Literacy or Spiritual Awareness? Comparative Critique of Andrew Wright's and David Hay's Approaches to Spiritual Education

    ERIC Educational Resources Information Center

    Filipsone, Anta

    2009-01-01

    On the basis of a comparison of the educational approaches of Andrew Wright and David Hay this paper illustrates the persisting problem of dichotomising cognitive and trans-cognitive aspects of spiritual development and education. Even though both Wright and Hay speak of the same topic--spirituality and spiritual education--they define these terms…

  19. Description of immatures and natural history of the weevil Loncophorus pustulatus (Champion, 1903) (Coleoptera: Curculionidae: Curculioninae) associated with flowers of Ceiba speciosa (A. St.-Hil.) Ravenna (Bombacoidea: Malvaceae) in southeast Brazil.

    PubMed

    Vanin, Sergio Antonio; Bená, Daniela de Cassia; Albertoni, Fabiano Fabian

    2013-01-01

    Larva and pupa of Loncophorus pustulatus (Champion, 1903) (Curculionidae: Curculioninae: Anthonomini) are described, illustrated and compared with descriptions of immatures of two other species of Loncophorus. Weevil larvae were found inside aborted flowers on the ground under Ceiba speciosa (A. St.-Hil.) Ravenna (Malvaceae), in the city of Sgo Paulo, State of S5o Paulo, and reared to adults in laboratory. Data obtained in the field and under laboratory conditions are presented. Parasitoidism of weevil larvae by wasps of the genus Catolaccus (Hymenoptera: Pteromalidae) is reported.

  20. The role of the U.S. Army Medical Department in domestic disaster assistance operations - lessons learned from hurricane Andrew.

    DOT National Transportation Integrated Search

    1996-04-01

    Hurricane Andrew, which struck South Dade County, Florida on the morning of 24 August 1992, was the "worst natural disaster ever to hit the United States..." The capabilities of the local and state governments to respond to the disaster were quickly ...

  1. STS-89 M.S. Andrew Thomas, Ph.D., participates in TCDT

    NASA Technical Reports Server (NTRS)

    1998-01-01

    STS-89 Mission Specialist Andrew Thomas, Ph.D., participates in a question and answer session for the media as part of Terminal Countdown Demonstration Test (TCDT) activities. The TCDT is held at KSC prior to each Space Shuttle flight to provide crews with an opportunity to participate in simulated countdown activities. The STS-89 mission will be the eighth docking of the Space Shuttle with the Russian Space Station Mir. After docking, Dr. Thomas will transfer to the space station, succeeding David Wolf, M.D., who will return to Earth aboard Endeavour. Dr. Thomas will live and work on Mir until June. STS-89 is scheduled for a Jan. 22 liftoff at 9:48 p.m.

  2. STS-89 M.S. Andrew Thomas waves to crowd during walkout

    NASA Technical Reports Server (NTRS)

    1998-01-01

    STS-89 Mission Specialist Andrew Thomas, Ph.D., smiles and waves his Australian hat to the crowd outside of the Operations and Checkout Building at KSC as he heads toward the Astrovan that will transport him to Launch Pad 39A. There, the Space Shuttle Endeavour awaits to take the STS-89 crew to Russia's Mir space station, where Dr. Thomas, who was born and educated in South Australia, will succeed David Wolf, M.D. STS-89, slated for a 9:48 p.m. EST liftoff Jan. 22, is the eighth docking with the Russian Space Station Mir, the first Mir docking for Endeavour (all previous dockings were made by Atlantis), and the first launch of 1998.

  3. STS-89 M.S. Andrew Thomas, poses the day before launch

    NASA Technical Reports Server (NTRS)

    1998-01-01

    STS-89 Mission Specialist Andrew Thomas, Ph.D., poses at KSC's Launch Pad 39A wearing a miniature koala bear on the day before the scheduled launch of Space Shuttle Endeavour that will carry him up to the Russian Space Station Mir. Final preparations are under way toward liftoff on Jan. 22 on the eighth mission to dock with Mir. After docking, Dr. Thomas will transfer to the space station, succeeding David Wolf, M.D., who will return to Earth aboard Endeavour. Dr. Thomas, who was born and educated in South Australia, will live and work on Mir until June. STS-89 is scheduled for liftoff at 9:48 p.m. EST.

  4. Insecticide resistance to permethrin and malathion and associated mechanisms in Aedes aegypti mosquitoes from St. Andrew Jamaica

    PubMed Central

    Francis, Sheena; Saavedra-Rodriguez, Karla; Perera, Rushika; Paine, Mark; Black, William C.

    2017-01-01

    The emergence of novel diseases spread by the Aedes aegypti mosquito in Jamaica and the Caribbean, has prompted studies on insecticide resistance towards effective management of the vector. Though Jamaica has been using the organophosphate insecticide malathion in its vector control program for more than 30 years, resistance to the pesticide has not been tested in over a decade. We analyzed resistance to malathion and the pyrethroid insecticide, permethrin on mosquitoes collected across St. Andrew, Jamaica, and analyzed the molecular basis of resistance. The Center for Disease Control (CDC) bioassay revealed that Ae. aegypti mosquitoes from St. Andrew, Jamaica were resistant to permethrin (15 μg/bottle) with mortalities at 0–8% at 30 minute exposure time, while contact with malathion (50 μg/bottle) revealed ≤ 50% mortality at 15 minutes, which increased to 100% at 45 minutes. The standard susceptible New Orleans (NO) strain exhibited 100% mortality within15 minutes. The activities of multifunction oxidases and p-nitro phenyl-acetate esterases were significantly greater in most Jamaican populations in comparison to the NO strain, while activities of glutathione-S-transferase, acetylcholinesterase, α-esterase and ß-esterase activity were relatively equal, or lower than that of the control strain. The frequency of knockdown resistance mutations in the voltage dependent sodium channel gene were measured. All collections were fixed for Cys1,534 while 56% of mosquitoes were Ile1,016/Val1,016 heterozygotes, and 33% were Ile1,016 homozygotes. Aedes aegypti from St. Andrew Jamaica are resistant to permethrin with variations in the mode of mechanism, and possibly developing resistance to malathion. Continued monitoring of resistance is critically important to manage the spread of the vector in the country. PMID:28650966

  5. Induction of apoptosis in human promyelocytic leukemia HL60 cells by an extract from Erythrina suberosa stem bark.

    PubMed

    Agrawal, Satyam Kumar; Agrawal, Madhunika; Sharma, Parduman Raj; Gupta, Bishan Datt; Arora, Saroj; Saxena, Ajit Kumar

    2011-01-01

    In this study, the apoptosis-inducing effect of an alcoholic extract from Erythrina suberosa stem bark (ESB) was investigated using human promyelocytic leukemia HL60 cells. Cell viability was estimated by MTT assay. We found that the ESB inhibited cell proliferation in a dose- and time-dependent manner. A series of well-documented morphological changes, such as cell shrinkage, condensation of nuclear chromatin, and nuclear fragmentation, were observed by fluorescence microscopy. The gold standard scanning electron micrographs showed apoptotic bodies and formation of blebs. Cell cycle analysis showed a significant increase in Sub G(0) population of cells above 50 μg/ml. ESB treatment resulted in a dose-dependent increase in annexin V positive cells. Increase in intracellular ROS production up to sixfold was detected in ESB-treated HL60 cells by DCFH-DA assay. Dissipation of mitochondrial membrane potential of intact cells accompanied by increase in cytosolic cytochrome c was observed, which was followed by activation of caspase-9 and -3 but not caspase-8. DNA fragmentation analysis revealed typical ladders as early as 18 h indicative of caspase-3 role in the apoptotic pathway. The overall results suggest that ESB induces mitochondria-mediated intrinsic apoptotic pathway in HL60 cells and might have therapeutic value against human leukemia.

  6. [The Andrew Heiskell Library for the Blind and Physically Handicapped.] A Library with a Difference. Projects and Experiments.

    ERIC Educational Resources Information Center

    Jarkon, Joe; Fitzpatrick, Vicki, Ed.

    This publication describes the Andrew Heiskell Library for the Blind and Physically Handicapped, a regional library for the National Library Service (NLS) example of the creative use of physical space and innovative technology. The publication focuses on the materials-handling system designed for the new facility, including system design…

  7. Climatic summaries and documentation for the primary meteorological station, H.J. Andrews Experimental Forest, 1972 To 1984.

    Treesearch

    Frederick A. Bierlmaler; Arthur McKee

    1989-01-01

    This report describes the primary meteorological station at the H.J. Andrews Experimental Forest (elev. 426 m, lat. 44°15' N., long. 122°10' W.) in the Willamette National Forest, the automatic digital data logger, sensors, and data-processing procedures used in measuring air temperature, dewpoint temperature, windspeed, precipitation, and solar radiation....

  8. Invertebrates of The H.J. Andrews Experimental Forest, Western Cascades, Oregon: I. An annotated checklist of fleas.

    Treesearch

    Robert E. Lewis; Chris Maser

    1981-01-01

    During a trapping survey of small mammals (approximately 3,000 individuals), species of fleas (1,632 specimens) were collected in the H.J. Andrews Experimental Forest, Western Cascades, Oregon. Host mammals were represented by 15 species—6 insectivores and 9 rodents captured from June through September. The collections extend our knowledge of the fauna of Oregon.

  9. 77 FR 15600 - Special Local Regulation; Emerald Coast Super Boat Grand Prix; Saint Andrew Bay; Panama City, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-16

    ...-AA08 Special Local Regulation; Emerald Coast Super Boat Grand Prix; Saint Andrew Bay; Panama City, FL... navigable waters during the Emerald Coast Super Boat Grand Prix high speed boat races. Entry into... Marine Event Permit on January 31, 2011 from Super Boat International, Inc. to conduct a high speed boat...

  10. The paths of Andrew A. Benson: a radio-autobiography.

    PubMed

    Nonomura, Arthur M; Holtz, Barry; Biel, Karl Y; Cooney, Robert; Lorimer, George; Govindjee

    2017-10-01

    Andrew A. Benson, one of the greatest biochemists of our time, is celebrated on his centennial by the authors with whom he interacted performing experiments or contemplating metabolic pathways in a wide range of biological kingdoms. He charted the chemical flow of energy in cells, tissues, organs, plants, animals, and ecosystems. Benson collaborated with hundreds of colleagues to examine the natural history of autotrophy, mixotrophy, and heterotrophy while elucidating metabolic pathways. We present here a biological perspective of his body of studies. Benson lived from September 24, 1917, to January 16, 2015. Out of over 1000 autoradiograms he produced in his life, he left a legacy of 50 labeled autoradiograms to the authors who tell the story of his life's work that resulted in Benson's Protocol (Nonomura et al., Photosynth Res 127:369-378, 2016) that has been applied, over the years, for the elucidation of major metabolic pathways by many scientists.

  11. Flow variation and substrate type affect dislodgement of the freshwater polychaete, Manayunkia speciosa

    USGS Publications Warehouse

    Malakauskas, David M.; Wilson, Sarah J.; Wilzbach, Margaret A.; Som, Nicholas A.

    2013-01-01

    We quantified microscale flow forces and their ability to entrain the freshwater polychaete, Manayunkia speciosa, the intermediate host for 2 myxozoan parasites (Ceratomyxa shasta and Parvicapsula minibicornis) that cause substantial mortalities in salmonid fishes in the Pacific Northwest. In a laboratory flume, we measured the shear stress associated with 2 mean flow velocities and 3 substrates and quantified associated dislodgement of polychaetes, evaluated survivorship of dislodged polychaetes, and observed behavioral responses of the polychaetes in response to increased flow. We used a generalized linear mixed model to estimate the probability of polychaete dislodgement for treatment combinations of velocity (mean flow velocity  =  55 cm/s with a shear velocity  =  3 cm/s, mean flow velocity  =  140 cm/s with a shear velocity  =  5 cm/s) and substrate type (depositional sediments and analogs of rock faces and the filamentous alga, Cladophora). Few polychaetes were dislodged at shear velocities <3 cm/s on any substrate. Above this level of shear, probability of dislodgement was strongly affected by both substrate type and velocity. After accounting for substrate, odds of dislodgement were 8× greater at the higher flow. After accounting for velocity, probability of dislodgement was greatest from fine sediments, intermediate from rock faces, and negligible from Cladophora. Survivorship of dislodged polychaetes was high. Polychaetes exhibited a variety of behaviors for avoiding increases in flow, including extrusion of mucus, burrowing into sediments, and movement to lower-flow microhabitats. Our findings suggest that polychaete populations probably exhibit high resilience to flow-mediated disturbances.

  12. Antibacterial activity of kecombrang flower extract (Nicolaia speciosa) microencapsulation with food additive materials formulation

    NASA Astrophysics Data System (ADS)

    Naufalin, R.; Rukmini, H. S.

    2018-01-01

    Kecombrang flower (Nicolaia speciosa) contains bioactive components of alkaloids, flavonoids, polyphenols, steroids, saponins, and essential oils as potential antimicrobials. The use of antibacterials in the form of essential oils has constraints; therefore microencapsulation needs to be done to prevent damage to the bioactive components. Microencapsulation can prevent degradation due to radiation or oxygen, easy-mix with foodstuffs and also slow the occurrence of evaporation. This study aimed to determine the effect of types of kecombrang extract, the concentration of microcapsules in food additives (NaCl and sucrose), and concentration of flower extract in the microcapsules. This study used Randomized Block Design (RBD) with 18 treatment combinations and two replications. Factors studied were types of kecombrang flower extract of (semi polar and polar extract), Food Additive types (sucrose and NaCl), the concentration of microcapsules in food additive (0%; 15%; 30% w /v). The results showed that polar and non-polar extract microcapsules produced antibacterial activity of 7.178 mm and 7.145 respectively of Bacillus cereus bacteria, while Escherichia coli was 7.272 mm and 7.289 mm respectively. A 30 percent microcapsule concentration provides antibacterial activity with inhibiting zone of 7, 818 mm for B. cereus and 8,045 for E.coli. Food Additive of sucrose concentrations showed that microcapsules produced tend to be more effective in inhibiting the growth of E.coli and B. cereus bacteria than that of NaCl, with each inhibition zone of 7.499 mm and 7.357 mm

  13. Healing and Antisecretory Effects of Aqueous Extract of Eremomastax speciosa (Acanthaceae) on Unhealed Gastric Ulcers.

    PubMed

    Amang, A P; Mezui, C; Siwe, G T; Emakoua, J; Mbah, G; Nkwengoua, E Z; Enow-Orock, G E; Tan, P V

    2017-01-01

    This work investigated the healing and antisecretory effects of the aqueous extract of Eremomastax speciosa on "unhealed gastric ulcers" associated with gastric acid hypersecretion. "Unhealed gastric ulcers" were induced using indomethacin following the establishment of acetic-acid-induced chronic gastric ulcers. The extract (200 and 400 mg/kg, per os) was administered concomitantly with indomethacin (1 mg/kg, subcutaneously). The effects of the extract on both basal and histamine-stimulated gastric acid secretion were determined. Mucus secretion and oxidative stress parameters were measured, and histological assessment of ulcer healing was carried out. The extract significantly promoted the healing process in rats subjected to "unhealed gastric ulcers" (82.4-88.5% healing rates). Treatment with the extract significantly reduced the basal (25.95-49.51% reduction rates) and histamine-stimulated (24.25-47.41%) acid secretions. The healing effect of the extract was associated with a significant ( p < 0.05) increase of mucus secretion and concentrations of antioxidant enzymes compared with the controls. The extract at the highest dose showed normalization of the mucosa, without glandular destruction and with the disappearance of fibrosis and lymphocyte infiltration. The abilities of the extract to increase mucus secretion, to reinforce antioxidant status, and to inhibit acid secretion would be some of the mechanisms by which this extract would accelerate the healing process in "unhealed gastric ulcers."

  14. A tale of two storms: Surges and sediment deposition from Hurricanes Andrew and Wilma in Florida’s southwest coast mangrove forests: Chapter 6G in Science and the storms-the USGS response to the hurricanes of 2005

    USGS Publications Warehouse

    Smith, Thomas J.; Anderson, Gordon H.; Tiling, Ginger

    2007-01-01

    Hurricanes can be very different from each other. Here we examine the impacts that two hurricanes, Andrew and Wilma, had in terms of storm surge and sediment deposition on the southwest coast of Florida. Although Wilma was the weaker storm, it had the greater impact. Wilma had the higher storm surge over a larger area and deposited more sediment than did Andrew. This effect was most likely due to the size of Wilma's eye, which was four times larger than that of Andrew.

  15. Mangroves, hurricanes, and lightning strikes: Assessment of Hurricane Andrew suggests an interaction across two differing scales of disturbance

    USGS Publications Warehouse

    Smith, Thomas J.; Robblee, Michael B.; Wanless, Harold R.; Doyle, Thomas W.

    1994-01-01

    The track of Hurricane Andrew carried it across one of the most extensive mangrove for ests in the New World. Although it is well known that hurricanes affect mangrove forests, surprisingly little quantitative information exists concerning hurricane impact on forest structure, succession, species composition, and dynamics of mangrove-dependent fauna or on rates of eco-system recovery (see Craighead and Gilbert 1962, Roth 1992, Smith 1992, Smith and Duke 1987, Stoddart 1969).After Hurricane Andrew's passage across south Florida, we assessed the environmental damage to the natural resources of the Everglades and Biscayne National Parks. Quantitative data collected during subsequent field trips (October 1992 to July 1993) are also provided. We present measurements of initial tree mortality by species and size class, estimates of delayed (or continuing) tree mortality, and observations of geomorphological changes along the coast and in the forests that could influence the course of forest recovery. We discuss a potential interaction across two differing scales of disturbance within mangrove forest systems: hurricanes and lightning strikes.

  16. Specific features of basalts from the western part of Andrew Bain Fault, Southwest Indian Ridge

    NASA Astrophysics Data System (ADS)

    Peyve, A. A.; Skolotnev, S. G.

    2017-12-01

    This paper reports original data on the composition of volcanic rocks in the western part of the Andrew Bain Fault of the South-West Indian Ridge obtained in the 23rd voyage of R/V Akademik Nikolai Strakhov. In accordance with high La/Th and low Nb/U ratios, the basalt compositions of stations S2317, S2318, and S2330 could result from melting of the DM-type source with HIMU traces. Meanwhile, the enriched samples of station S2326 correspond to a mantle source with a considerable contribution of recycled sediments (EM). Sample S2326/35, which is composed of a melt almost completely depleted in EM material, corresponds to the volcanic rocks of the Marion and Prince Edward islands. The obtained and available data on the SWIR segment from Bouvet Island to Andrew Bain Fault are indicative of small mantle heterogeneities in this region. Two possible variants of their origin are considered: either preservation of the enriched material fragments in the depleted mantle during the split of Gondwana or "contamination" of the mantle with plume material with the formation of vein irregularities before opening of the ocean in this region. In the latter case, the plume material could cover a huge area not constrained by the young plume magmatism regions on Bouvet, Marion, and Prince Edward islands.

  17. Potent apoptosis-inducing activity of erypoegin K, an isoflavone isolated from Erythrina poeppigiana, against human leukemia HL-60 cells.

    PubMed

    Hikita, Kiyomi; Hattori, Natsuki; Takeda, Aya; Yamakage, Yuko; Shibata, Rina; Yamada, Saori; Kato, Kuniki; Murata, Tomiyasu; Tanaka, Hitoshi; Kaneda, Norio

    2018-01-01

    Erypoegin K is an isoflavone isolated from the stem bark of Erythrina poeppigiana. It contains a furan group at the A-ring of the core isoflavone structure and can inhibit the activity of glyoxalase I, an enzyme that catalyzes the detoxification of methylglyoxal (MG), a by-product of glycolysis. In the present study, we found that erypoegin K has a potent cytotoxic effect on human leukemia HL-60 cells. Its cytotoxic effect was much stronger than that of a known glyoxalase I inhibitor S-p-bromobenzylglutathione cyclopentyl diester. Conversely, erypoegin K demonstrated weak cytotoxicity toward normal human peripheral lymphocytes. The treatment of HL-60 cells with erypoegin K significantly induced caspase-3 activity, whereas the pretreatment of the cells with caspase-3 inhibitor suppressed erypoegin K-induced cell death. Furthermore, nuclear condensation and apoptotic genome DNA fragmentation were observed in erypoegin K-treated HL-60 cells. These results indicated that the observed cell death was mediated by apoptosis. In addition, the toxic compound MG was highly accumulated in the culture medium of erypoegin K-treated HL-60 cells, suggesting that cell apoptosis was triggered by extracellular MG. The present study showed that erypoegin K has a potent apoptosis-inducing effect on cancerous cell lines, such as HL-60.

  18. Invertebrates of The H.J. Andrews Experimental Forest, Western Cascade Mountains, Oregon: IV. The Oribatid Mites (Acari: Cryptostigmata).

    Treesearch

    Andrew Moldenke; Becky Fichter

    1988-01-01

    A fully illustrated key is presented for identifying genera of oribatid mites known from or suspected of occurring in the Pacific Northwest. The manual includes an introduction detailing sampling methodology; an illustrated glossary of all terminology used; two color plates of all taxa from the H. J. Andrews Experimental Forest; a diagrammatic key to the 16 major...

  19. Invertebrates of the H.J. Andrews Experimental Forest, western Cascades, Oregon II. an annotated checklist of caddisflies (Trichoptera)

    Treesearch

    N.H. Anderson; G.M. Cooper; D.G Denning

    1982-01-01

    At least 99 species, representing 14 families of Trichoptera, are recorded from the H.J. Andrews Experimental Forest, near Blue River, Oregon. The collecting sites include a wide diversity of environmental conditions in a 6000-hectare watershed of the western Cascade Range (from 400 to 1 630 meters in altitude and from 1st- to 7th-order streams).

  20. 33 CFR 334.760 - Naval Support Activity Panama City and Alligator Bayou, a tributary of St. Andrew Bay, Fla...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... City and Alligator Bayou, a tributary of St. Andrew Bay, Fla.; naval restricted area. 334.760 Section... DEFENSE DANGER ZONE AND RESTRICTED AREA REGULATIONS § 334.760 Naval Support Activity Panama City and... permission from the Officer in Charge, Naval Support Activity Panama City, Panama City Beach, Florida, or his...

  1. 33 CFR 334.760 - Naval Support Activity Panama City and Alligator Bayou, a tributary of St. Andrew Bay, Fla...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... City and Alligator Bayou, a tributary of St. Andrew Bay, Fla.; naval restricted area. 334.760 Section... DEFENSE DANGER ZONE AND RESTRICTED AREA REGULATIONS § 334.760 Naval Support Activity Panama City and... permission from the Officer in Charge, Naval Support Activity Panama City, Panama City Beach, Florida, or his...

  2. Protocols for Biotechnological Interventions in Improvement of Vanilla (Vanilla planifolia Andrews.).

    PubMed

    Divakaran, Minoo; Babu, K Nirmal; Peter, K V

    2016-01-01

    Vanilla (Vanilla planifolia Andrews (syn. V. fragrans Salisb.), a native of Central America, is the primary source of natural vanillin and plays a major role in the global economy. The gene pool of vanilla is threatened by deforestation and overcollection that has resulted in disappearance of natural habitats and wild species. Continuous vegetative propagation and lack of natural seed set and sufficient variations in the gene pool hamper crop improvement programs. In vitro techniques, one of the key tools of plant biotechnology, can be employed for overcoming specific problems, viz. production of disease-free clones, inducing somaclonal variations, developing hybrids, gene pool conservation, incorporating desired traits by distant hybridization, genetic engineering, etc. However, realization of these objectives necessitates standardization of protocols. This chapter describes the various protocols optimized for crop improvement in Vanilla species.

  3. Age- specific incidence of cancer in Kingston and St. Andrew, Jamaica. Part I: 1978-1982.

    PubMed

    Brooks, S E; Wolff, C

    1991-09-01

    A total of 3,396 malignant neoplasms were recorded in Kingston and St. Andrew, Jamaica during 1978 to 1982. There were 1,477 males and 1,919 females. Histological confirmation was achieved in 88.4%. The crude incidence rate for males for all age groups was 107.8 per 100,000 per year; in females, the figure was 123.0. The age-standardized rates (world population) were 157.9 for males and 159.1 for females. Age-specific rates by site, sex, and age are tabulated.

  4. Chemical Composition and Bioactivities of Two Common Chaenomeles Fruits in China: Chaenomeles speciosa and Chaenomeles sinensis.

    PubMed

    Miao, Jing; Zhao, Chengcheng; Li, Xia; Chen, Xuetao; Mao, Xinhui; Huang, Hanhan; Wang, Tingting; Gao, Wenyuan

    2016-08-01

    Contents of total flavonoids, total phenolics, total triterpenes, total condensed tannin and total saponins in peels, flesh and endocarps of Chaenomeles speciosa (CSP) and Chaenomeles sinensis (CSS) were determined by colorimetric method, while 5 phenolics (vanillic, gallic, chlorogenic, ferulic and p-coumaric acids), 2 triterpenes (oleanolic and ursolic acids), and 3 flavonoids (rutin, catechin and epicatechin) were identified and quantified by high-performance liquid chromatography-mass spectrometry (HPLC-MS) and HPLC, and antioxidant and α-glucosidase inhibitory activities of them also were evaluated as well as their digestive characteristics. In the correlation analysis, total phenolics, vanillic acid, catechin, ursolic acid and oleanolic acid all contribute to DPPH(·) scavenge capacity, gallic acid contributes to total ferric reducing antioxidant power, while total triterpenes, total saponins, chlorogenic acid and ferullic acid contribute to α-glucosidase inhibitory activity. In the principal component analysis, endocarps of CSP and CSS both show better quality than their peels and flesh, respectively. In vitro digestion can increase contents of total flavonoids, total condensed tannin and total saponins, while contents of total phenolics and total triterpenes decreased greatly. Our study would contribute to the full use of discarded parts of the 2 Chaenomeles and be helpful to establish a good foundation for further research of CSP and CSS. © 2016 Institute of Food Technologists®

  5. Healing and Antisecretory Effects of Aqueous Extract of Eremomastax speciosa (Acanthaceae) on Unhealed Gastric Ulcers

    PubMed Central

    Amang, A. P.; Mezui, C.; Siwe, G. T.; Emakoua, J.; Mbah, G.; Nkwengoua, E. Z.; Enow-Orock, G. E.

    2017-01-01

    Objective This work investigated the healing and antisecretory effects of the aqueous extract of Eremomastax speciosa on “unhealed gastric ulcers” associated with gastric acid hypersecretion. Materials and Methods “Unhealed gastric ulcers” were induced using indomethacin following the establishment of acetic-acid-induced chronic gastric ulcers. The extract (200 and 400 mg/kg, per os) was administered concomitantly with indomethacin (1 mg/kg, subcutaneously). The effects of the extract on both basal and histamine-stimulated gastric acid secretion were determined. Mucus secretion and oxidative stress parameters were measured, and histological assessment of ulcer healing was carried out. Results The extract significantly promoted the healing process in rats subjected to “unhealed gastric ulcers” (82.4–88.5% healing rates). Treatment with the extract significantly reduced the basal (25.95–49.51% reduction rates) and histamine-stimulated (24.25–47.41%) acid secretions. The healing effect of the extract was associated with a significant (p < 0.05) increase of mucus secretion and concentrations of antioxidant enzymes compared with the controls. The extract at the highest dose showed normalization of the mucosa, without glandular destruction and with the disappearance of fibrosis and lymphocyte infiltration. Conclusion The abilities of the extract to increase mucus secretion, to reinforce antioxidant status, and to inhibit acid secretion would be some of the mechanisms by which this extract would accelerate the healing process in “unhealed gastric ulcers.” PMID:29234676

  6. STS-89 M.S. Andrew Thomas, Ph.D., participates in TCDT

    NASA Technical Reports Server (NTRS)

    1998-01-01

    STS-89 Mission Specialist Andrew Thomas, Ph.D. gets ready to drive an M-113 armored personnel carrier as part of Terminal Countdown Demonstration Test (TCDT) activities. The TCDT is held at KSC prior to each Space Shuttle flight to provide crews with an opportunity to participate in simulated countdown activities. Standing inside the M-113 is Dr. Thomas while George Hoggard, a training officer with KSC Fire Services, sits atop the vehicle. The STS-89 mission will be the eighth docking of the Space Shuttle with the Russian Space Station Mir. After docking, Dr. Thomas will transfer to the space station, succeeding David Wolf, M.D., who will return to Earth aboard Endeavour. Dr. Thomas will live and work on Mir until June. STS-89 is scheduled for a Jan. 22 liftoff at 9:48 p.m.

  7. Astronaut Andrew S. W. Thomas, mission specialist, interrupts a Spacehab task to pose for an

    NASA Technical Reports Server (NTRS)

    1996-01-01

    STS-77 ESC VIEW --- Astronaut Andrew S. W. Thomas, mission specialist, interrupts a Spacehab task to pose for an Electronic Still Camera (ESC) snapshot inside the Spacehab Module onboard the Earth-orbiting Space Shuttle Endeavour. In upper left is the view port which crew members had used for viewing and photographing operations with the Spartan 207/Inflatable Antenna Experiment (IAE). Thomas has his hand on an aft-bulkhead-mounted locker. The Space Experiment Facility (SEF), designed and managed by the University of Alabama, is just behind his left shoulder.

  8. Supplemental Environmental Assessment of the Ambulatory Care Center at Joint Base Andrews-Naval Air Facility Washington, Maryland

    DTIC Science & Technology

    2011-06-01

    DOLAN, GS-14, USAF Chief, Asset Management Flight MARYLAND DEPARTMENT OF THE ENVIRONMENT MDE Martin O’Malley Governor 1800 Washington Boulevard...t.e.(~;vJ ~-so- ll ( HtfM.;r-\\<.U ) -l. ~- II J~~ Ms. Anne Hodges March 29, 2011 Page Two Again, thank you for giving MDE the opportunity to...Joane D. Mueller MDE Clearinghouse Coordinator Office of Communications Enclosure cc: Bob Rosenbush, State Clearinghouse • Andrews Airforce Base

  9. Kulusuk Icebergs, by Andrew Bossi

    NASA Image and Video Library

    2017-12-08

    GPM "Let it Snow" Photo Contest Winners The Global Precipitation Measurement mission is happy to announce the top ten winners of the "Let It Snow" photo competition. Thank you to everyone who submitted their best pictures of winter. From January 7th through February 4th 2013, over 1,000 photos were submitted via Flickr and Instagram (see the Flickr submissions here: bit.ly/VVEubh). We loved all of your entries and thoroughly appreciate your participation. About this image: Kulusuk Icebergs, by Andrew Bossi Location: On approach to the airstrip at Kulusuk, Greenland, located on the east coast. The flight departed out of Reykjavík, Iceland. How this Photo Was Taken: "My write-up of the day covers things in decent detail. Basically my vacation was focused on Scandinavia and hadn't even considered Greenland, but while traveling around Iceland I'd become aware that day trips were offered and I leapt at the opportunity. This approach was my first sight of Greenland. While I've seen plenty of glaciers and mountains, I'd never seen anything like this - it started with endless fields of ice amid the deep blue sea, and some minutes later a wall of frozen rock rose up from the horizon. I'd never seen anything so beautiful. I think my camera's shutter was snapping almost endlessly right up until we landed. The landing itself was an experience, as our tiny plane descended between the mountains -- rockfaces just outside each window -- and set down on a gravel runway." About Photographer Steven Sandner: More info about this photo: intentionallylost.blogspot.com/2011/06/gl-kulusuk.htm www.flickr.com/photos/thisisbossi/ twitter.com/thisisbossi NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on

  10. Hurricane Andrew Damage in Relation to Wood Decay Fungi and Insects in Bottomland Hardwoods of the Atchafalaya Basin, Louisiana

    Treesearch

    Theodor D. Leininger; A. Dan Wilson; Donald G. Lester

    1997-01-01

    Hurricane Andrew caused damage to more than 780 sq.km of bottomland hardwood and cypress-tupelo forests in the Atchafalaya Basin of Louisiana in August 1992. Trees in bottomland hardwood sites were examined, in early May 1994, for signs and symptoms of wood decay fungi, and for insect damage, ostensibly present before the hurricane, which may have predisposed trees to...

  11. Insect Seed Predators in Erythrina falcata (Fabaceae): Identification of Predatory Species and Ecological Consequences of Asynchronous Flowering.

    PubMed

    Pereira, C M; Moura, M O; Da-Silva, P R

    2014-06-01

    Seed predation by insects exerts negative effects on plant reproduction by limiting the supply of seeds and preventing germination. Seed predators of the family Fabaceae are usually generalists, which increases the rate of predation. One strategy to minimize seed predation, developed by plants from temperate regions, is "escape in time," i.e., flowering before or after the peak of predation. For tropical species, few studies have investigated the strategies used by plants to minimize seed predation. Here, using Erythrina falcata, a tropical species of Fabaceae, we test three main hypotheses: (i) escape in time is a mechanism used by E. falcata to minimize seed predation, (ii) the predators of E. falcata seeds are generalists, and (iii) the biometric variables of the pods can influence seed predation. In order to test these hypotheses, we determined the flowering time of E. falcata, rate of seed predation, the predators insects, and biometric variables of the pods. The analyzed trees were grouped into three classes: "early," "peak," and "late" flowering. The average seed predation rates on trees in the early and late classes were 65% and 50%, respectively, and in the peak class, 80%; thus, our first hypothesis can be accepted. Three species of Lepidoptera and two of Coleoptera were found preying on E. falcata seeds. These species were observed to be generalist predators; thus, our second hypothesis can be accepted. The biometric variables of the pods cannot influence seed predation rate. The ecological consequences of asynchronous flowering on plants and insects are discussed.

  12. Andrew Liehr and the structure of Jahn-Teller surfaces

    NASA Astrophysics Data System (ADS)

    Chibotaru, Liviu F.; Iwahara, Naoya

    2017-05-01

    The present article is an attempt to draw attention to a seminal work by Andrew Liehr “Topological aspects of conformational stability problem” [1, 2] issued more than half century ago. The importance of this work stems from two aspects of static Jahn-Teller and pseudo-Jahn-Teller problems fully developed by the author. First, the work of Liehr offers an almost complete overview of adiabatic potential energy surfaces for most known Jahn-Teller problems including linear, quadratic and higher-order vibronic couplings. Second, and most importantly, it identifies the factors defining the structure of Jahn-Teller surfaces. Among them, one should specially mention the minimax principle stating that the distorted Jahn-Teller systems tend to preserve the highest symmetry consistent with the loss of their orbital degeneracy. We believe that the present short reminiscence not only will introduce a key Jahn-Teller scientist to the young members of the community but also will serve as a vivid example of how a complete understanding of a complex problem, which the Jahn-Teller effect certainly was in the beginning of 1960s, can be achieved.

  13. Usage of the Secondary School Admission Test (SSAT) at St. Andrew's School as a Predictor of Academic Success

    ERIC Educational Resources Information Center

    Alleyne, Eduardo A.

    2016-01-01

    The purpose of this quantitative study is to replicate and advance Kiley & Gable's (2013) work in examining the empirical relationship between SSAT scores and academic outcomes. Data is used relating to students accepted and enrolled in 9th grade at St. Andrew's School--a private elite boarding school--in the Fall of 2010 and Fall of 2011.…

  14. Anti-Fatigue and Antioxidant Activity of the Polysaccharides Isolated from Millettiae speciosae Champ. Leguminosae

    PubMed Central

    Zhao, Xiao-Ning; Liang, Jia-Li; Chen, Han-Bin; Liang, Ye-Er; Guo, Hui-Zhen; Su, Ze-Ren; Li, Yu-Cui; Zeng, Hui-Fang; Zhang, Xiao-Jun

    2015-01-01

    Millettiae speciosae Champ. Leguminosae (MSC), is a well-known Chinese herb traditionally used as food material and medicine for enhancing physical strength. Our preliminary study found that the aqueous extract of this herb (MSE) had an anti-fatigue effect. In this paper, we further separated MSE into total polysaccharides (MSP) and supernatant (MSS) by alcohol precipitation, and explored which fraction was active for its anti-fatigue effect. Mice were orally administered with MSP or MSS at the doses of 200, 400, and 800 mg/kg for 20 days and the anti-fatigue effect was assessed by exhaustive swimming exercise (ESE). The biochemical parameters related to fatigue after ESE and the in vitro antioxidant activity of active fraction were determined. Our results showed that MSP, instead of MSS, significantly extended the swimming time to exhaustion (p < 0.05), indicating that MSP is responsible for the anti-fatigue effect of MSE. In addition, MSP treatment increased the levels of glucose (Glu) and muscle glycogen, whereas it decreased the accumulations of blood urea nitrogen (BUN) and lactic acid (Lac). Moreover, ESE increased the levels of creatine phosphokinase (CK), lactic dehydrogenase (LDH), and malondialdehyde (MDA) but reduced superoxide dismutase (SOD) and glutathione (GSH) in plasma. In contrast, MSP inhibited all the above changes relating to fatigue. Furthermore, an in vitro antioxidant test revealed that MSP dose-dependently scavenged ·OH and DPPH free radicals. Taken together, these findings strongly suggested that MSP was able to alleviate physical fatigue by increasing energy resources and decreasing accumulation of detrimental metabolites. The antioxidant activity may crucially contribute to the observed anti-fatigue effect of MSP. PMID:26506375

  15. Antinociceptive action of isolated mitragynine from Mitragyna Speciosa through activation of opioid receptor system.

    PubMed

    Shamima, Abdul Rahman; Fakurazi, Sharida; Hidayat, Mohamad Taufik; Hairuszah, Ithnin; Moklas, Mohamad Aris Mohd; Arulselvan, Palanisamy

    2012-01-01

    Cannabinoids and opioids systems share numerous pharmacological properties and antinociception is one of them. Previous findings have shown that mitragynine (MG), a major indole alkaloid found in Mitragyna speciosa (MS) can exert its antinociceptive effects through the opioids system. In the present study, the action of MG was investigated as the antinociceptive agent acting on Cannabinoid receptor type 1 (CB1) and effects on the opioids receptor. The latency time was recorded until the mice showed pain responses such as shaking, licking or jumping and the duration of latency was measured for 2 h at every 15 min interval by hot plate analysis. To investigate the beneficial effects of MG as antinociceptive agent, it was administered intraperitoneally 15 min prior to pain induction with a single dosage (3, 10, 15, 30, and 35 mg/kg b.wt). In this investigation, 35 mg/kg of MG showed significant increase in the latency time and this dosage was used in the antagonist receptor study. The treated groups were administered with AM251 (cannabinoid receptor-1 antagonist), naloxone (non-selective opioid antagonist), naltrindole (δ-opioid antagonist) naloxonazine (μ(1)-receptor antagonist) and norbinaltorpimine (κ-opioid antagonist) respectively, prior to administration of MG (35 mg/kg). The results showed that the antinociceptive effect of MG was not antagonized by AM251; naloxone and naltrindole were effectively blocked; and norbinaltorpimine partially blocked the antinociceptive effect of MG. Naloxonazine did inhibit the effect of MG, but it was not statistically significant. These results demonstrate that CB1 does not directly have a role in the antinociceptive action of MG where the effect was observed with the activation of opioid receptor.

  16. Anti-Fatigue and Antioxidant Activity of the Polysaccharides Isolated from Millettiae speciosae Champ. Leguminosae.

    PubMed

    Zhao, Xiao-Ning; Liang, Jia-Li; Chen, Han-Bin; Liang, Ye-Er; Guo, Hui-Zhen; Su, Ze-Ren; Li, Yu-Cui; Zeng, Hui-Fang; Zhang, Xiao-Jun

    2015-10-21

    Millettiae speciosae Champ. Leguminosae (MSC), is a well-known Chinese herb traditionally used as food material and medicine for enhancing physical strength. Our preliminary study found that the aqueous extract of this herb (MSE) had an anti-fatigue effect. In this paper, we further separated MSE into total polysaccharides (MSP) and supernatant (MSS) by alcohol precipitation, and explored which fraction was active for its anti-fatigue effect. Mice were orally administered with MSP or MSS at the doses of 200, 400, and 800 mg/kg for 20 days and the anti-fatigue effect was assessed by exhaustive swimming exercise (ESE). The biochemical parameters related to fatigue after ESE and the in vitro antioxidant activity of active fraction were determined. Our results showed that MSP, instead of MSS, significantly extended the swimming time to exhaustion (p < 0.05), indicating that MSP is responsible for the anti-fatigue effect of MSE. In addition, MSP treatment increased the levels of glucose (Glu) and muscle glycogen, whereas it decreased the accumulations of blood urea nitrogen (BUN) and lactic acid (Lac). Moreover, ESE increased the levels of creatine phosphokinase (CK), lactic dehydrogenase (LDH), and malondialdehyde (MDA) but reduced superoxide dismutase (SOD) and glutathione (GSH) in plasma. In contrast, MSP inhibited all the above changes relating to fatigue. Furthermore, an in vitro antioxidant test revealed that MSP dose-dependently scavenged ·OH and DPPH free radicals. Taken together, these findings strongly suggested that MSP was able to alleviate physical fatigue by increasing energy resources and decreasing accumulation of detrimental metabolites. The antioxidant activity may crucially contribute to the observed anti-fatigue effect of MSP.

  17. Fermionic solution of the Andrews-Baxter-Forrester model. II. Proof of Melzer`s polynomial identities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Warnaar, S.O.

    1996-07-01

    We compute the one-dimensional configuration sums of the AFB model using the fermionic techniques introduced in part I of this paper. Combined with the results of Andrews, Baxter, and Forrester, we prove polynominal identities for finitizations of the Virasoro characters {sub {chi}b, a}{sup (r-1, r)}(q) as conjectured by Melzer. In the thermodynamic limit these identities reproduce Rogers-Ramanujan-type identities for the unitary minimal Virasoro characters conjectured by the Stony Brook group. We also present a list of additional Virasoro character identities which follow from our proof of Melzer`s identities and application of Bailey`s lemma.

  18. Characterization and Pharmacological Properties of a Novel Multifunctional Kunitz Inhibitor from Erythrina velutina Seeds

    PubMed Central

    Machado, Richele J. A.; Monteiro, Norberto K. V.; Migliolo, Ludovico; Silva, Osmar N.; Pinto, Michele F. S.; Oliveira, Adeliana S.; Franco, Octávio L.; Kiyota, Sumika; Bemquerer, Marcelo P.; Uchoa, Adriana F.; Morais, Ana H. A.; Santos, Elizeu A.

    2013-01-01

    Inhibitors of peptidases isolated from leguminous seeds have been studied for their pharmacological properties. The present study focused on purification, biochemical characterization and anti-inflammatory and anticoagulant evaluation of a novel Kunitz trypsin inhibitor from Erythrina velutina seeds (EvTI). Trypsin inhibitors were purified by ammonium sulfate (30–60%), fractionation followed by Trypsin-Sepharose affinity chromatography and reversed-phase high performance liquid chromatography. The purified inhibitor showed molecular mass of 19,210.48 Da. Furthermore, a second isoform with 19,228.16 Da was also observed. The inhibitor that showed highest trypsin specificity and enhanced recovery yield was named EvTI (P2) and was selected for further analysis. The EvTI peptide fragments, generated by trypsin and pepsin digestion, were further analyzed by MALDI-ToF-ToF mass spectrometry, allowing a partial primary structure elucidation. EvTI exhibited inhibitory activity against trypsin with IC50 of 2.2×10−8 mol.L−1 and constant inhibition (Ki) of 1.0×10−8 mol.L−1, by a non-competitive mechanism. In addition to inhibit the activity of trypsin, EvTI also inhibited factor Xa and neutrophil elastase, but do not inhibit thrombin, chymotrypsin or peptidase 3. EvTI was investigated for its anti-inflammatory and anti-coagulant properties. Firstly, EvTI showed no cytotoxic effect on human peripheral blood cells. Nevertheless, the inhibitor was able to prolong the clotting time in a dose-dependent manner by using in vitro and in vivo models. Due to anti-inflammatory and anticoagulant EvTI properties, two sepsis models were here challenged. EvTI inhibited leukocyte migration and specifically acted by inhibiting TNF-α release and stimulating IFN-α and IL-12 synthesis. The data presented clearly contribute to a better understanding of the use of Kunitz inhibitors in sepsis as a bioactive agent capable of interfering in blood coagulation and inflammation. PMID

  19. PHYSICOCHEMICAL PROPERTIES OF THE PROTEOLYTIC ENZYME FROM THE LATEX OF THE MILKWEED, ASCLEPIAS SPECIOSA TORR. SOME COMPARISONS WITH OTHER PROTEASES

    PubMed Central

    Winnick, Theodore; Davis, Alva R.; Greenberg, David M.

    1940-01-01

    1. A study has been made of the properties of a hitherto unreported proteolytic enzyme from the latex of the milkweed, Asclepias speciosa. The new protease has been named asclepain by the authors. 2. The results of chemical, diffusion, and denaturation tests indicate that asclepain is a protein. 3. Like papain, asclepain dots milk and digests most proteins, particularly if they are dissolved in concentrated urea solution. Unlike papain, asclepain did not clot blood. 4. The activation and inhibition phenomena of asclepain resemble those of papain, and seem best explained on the assumption that free sulfhydryl in the enzyme is necessary for proteolytic activity. The sulfhydryl of asclepain appears more labile than that of papain. 5. The measurement of pH-activity curves of asclepain on casein, ovalbumin, hemoglobin, edestin, and ovovitellin showed no definite digestion maxima for most of the undenatured proteins, while in urea solution there were well defined maxima near pH 7.0. Native hemoglobin and ovovitellin were especially undigestible, while native casein was rapidly attacked. 6. Temperature-activity curves were determined for asclepain on hemoglobin, casein, and milk solutions. The optimum temperature was shown to increase with decreasing time of digestion. PMID:19873154

  20. Effects of indian coral tree, Erythrina indica lectin on eggs and larval development of melon fruit fly, Bactrocera cucurbitae.

    PubMed

    Singh, Kuljinder; Kaur, Manpreet; Rup, Pushpinder J; Singh, Jatinder

    2009-07-01

    Present study was undertaken to investigate the influence of D-galactose binding lectin from Erythrina indica Lam. on the eggs and second instar larvae (64-72 hr) of melon fruit fly, Bactrocera cucurbitae (Coquillett). The lectin from E. indica seeds was extracted and purified by affinity chromatography using asilofetuin linked porous amino activated silica beads. The effects of various concentrations (0, 125, 250, 500 and 1000 microg ml(-1)) of lectin were studied on freshly laid eggs (0-8 hr) of B. cucurbitae which showed non-significant reduction in percent hatching of eggs. However, the treatment of second instar larvae (64-72 hr) with various test concentrations (0, 25, 50, 100 and 200 microg ml(-1)) of lectin significantly reduced the percent pupation and percent emergence of B. cucurbitae depicting a negative correlation with the lectin concentration. The LC50 (81 microg ml(-1)) treatment significantly decreased the pupal weight. Moreover, the treatment of larvae had also induced a significant increase in the remaining development duration. The activity of three hydrolase enzymes (esterases, acid and alkaline phosphatases), one oxidoreductase (catalase) and one group transfer enzyme (glutathione S-transferases) was assayed in second instar larvae under the influence of LC50 concentration of lectin for three exposure intervals (24, 48 and 72 hr). It significantly suppressed the activity of all the enzymes after all the three exposure intervals except for esterases which increased significantly.

  1. Invertebrates of The H.J. Andrews Experimental Forest, Western Cascade Range, Oregon. V: An Annotated List of Insects and Other Arthropods

    Treesearch

    Gary L. Parson; Gerasimos Cassis; Andrew R. Moldenke; John D. Lattin; Norman H. Anderson; Jeffrey C Miller; Paul Hammond; Timothy D. Schowalter

    1991-01-01

    An annotated list of species of insects and other arthropods that have been collected and studies on the H.J. Andrews Experimental forest, western Cascade Range, Oregon. The list includes 459 families, 2,096 genera, and 3,402 species. All species have been authoritatively identified by more than 100 specialists. Information is included on habitat type, functional group...

  2. Invertebrates of The H.J. Andrews Experimental Forest, western Cascade Range, Oregon. V: An annotated list of insects and other arthropods.

    Treesearch

    Gary L. Parson; Gerasimos Cassis; Andrew R. Moldenke; John D. Lattin; Norman H. Anderson; Jeffrey C Miller; Paul Hammond; Timothy D. Schowalter

    1991-01-01

    An annotated list of species of insects and other arthropods that have been collected and studies on the H.J. Andrews Experimental forest, western Cascade Range, Oregon. The list includes 459 families, 2,096 genera, and 3,402 species. All species have been authoritatively identified by more than 100 specialists. Information is included on habitat type, functional group...

  3. Cytotoxic activity of erypogein d from erythrina poeppigiana (leguminosae) against cervical cancer (HeLa), breast cancer (MCF-7) and ovarian cancer (SKOV-3) cells

    NASA Astrophysics Data System (ADS)

    Herlina, T.; Gaffar, S.; Widowati, W.

    2018-05-01

    Cancer is the uncontrolled growth of abnormal cells and continues to divide rapidly in the body. Current anticancer treatment usually causes many side effects. Natural products are then explored to be new alternatives for cancer treatment. Flavonoids have been known to possess medicinal properties, including anticancer. This study was performed to observe the cytotoxic activity of isoflavanone compound, erypogein D from Erythrina poeppigiana, toward cervical cancer (HeLa), breast cancer (MCF-7) and ovarian cancer (SKOV-3) cells. The cytotoxic activity of erypogein D was tested using MTS (3-(4,5-dimethylthiazol-2-yl)-5-(3- carboxyme-thoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium) assay. The percentage of cell mortality was calculated and the IC50 was analyzed using probit analysis. The result showed that cytotoxic activity of the erypogein D against HeLa, SKOV-3, and MCF-7 cells had an IC50 value 225, 70.74, and 30.12 μM, respectively. Based on IC50 value can be concluded that erypogein D is the most cytotoxic to breast cancer MCF-7 cell. However the cytotoxic activity of erypogein D toward MCF7 is moderate.

  4. Tilting at wave beams: a new perspective on the St Andrew's Cross

    NASA Astrophysics Data System (ADS)

    Akylas, T. R.; Kataoka, T.; Ghaemsaidi, S. J.; Holzenberger, N.; Peacock, T.

    2017-11-01

    The generation of internal gravity waves by a vertically oscillating cylinder that is tilted to the horizontal in a stratified fluid of constant buoyancy frequency, is investigated theoretically and experimentally. This forcing arrangement leads to a variant of the classical St Andrew's Cross that has certain unique features: (i) radiation of wave beams is limited due to a lower cut-off frequency set by the cylinder tilt angle to the horizontal; (ii) the response is essentially three-dimensional, as end effects eventually come into play when the cut-off frequency is approached, however long a cylinder might be. These results follow from kinematic considerations and are also confirmed by laboratory experiments. The kinematic analysis, moreover, suggests a resonance phenomenon near the cut-off frequency, where viscous and nonlinear effects are likely to play an important part. This scenario is examined by an asymptotic model as well as experimentally. Supported in part by NSF Grant DMS-1512925.

  5. Carcass characteristics and meat quality of lambs fed babassu cake (Orbignya speciosa) as a replacement for elephant grass silage.

    PubMed

    Luz, Janaina Barros; Alves, Kaliandra Souza; Mezzomo, Rafael; Ribeiro Dos Santos Neta, Ernestina; Gomes, Daiany Íris; Sampaio Oliveira, Luis Rennan; Silva, Josiane Costa; Ramos de Carvalho, Francisco Fernando

    2017-01-01

    The study aimed to evaluate the effect of the partial replacement of elephant grass silage with babassu cake (Orbignya speciosa) on the carcass characteristics and meat quality of feedlot lambs. Forty-five castrated male Santa Ines sheep (19.08 ± 0.41 kg) approximately 4 months old were distributed in a completely randomized design, with five treatments 0.0, 12.5, 25.0, 37.5 and 50 % (%DM) replacement of babassu cake with silage forming isoproteic diets formulated at a ratio of 40 % roughage to 60 % concentrate. All of the studied animals were slaughtered at the end of the experiment. The liver weights and yields increased with the inclusion of babassu cake. The weight of the shoulder increased from 2.31 to 2.61 kg, while the loin yield decreased from 7.38 to 6.64 % with the inclusion of babassu cake, both linearly. The body length, thoracic perimeter, rump perimeter and carcass compactness index showed high and positive correlations with the hot and cold carcass weights. The myofibrillar fragmentation index decreased linearly as a function of the inclusion level of babassu cake, but other quality variables were not affected. The replacement of up to 50 % of the elephant grass silage with babassu cake in the diet of lambs does not cause negative effects on carcass characteristics or meat quality.

  6. Photocatalytic activity against azo dye and cytotoxicity on MCF-7 cell lines of zirconium oxide nanoparticle mediated using leaves of Lagerstroemia speciosa.

    PubMed

    Sai Saraswathi, V; Santhakumar, K

    2017-04-01

    Metal oxide nanoparticles are gaining interest in recent years. The present paper explains about the green synthesis of zirconium oxide nanoparticles (ZrO NPs) mediated from the leaves of Lagerstroemia speciosa. The prepared ZrO NPs were characterized by UV-vis spectroscopy, FT-IR, X-ray diffraction analysis (XRD), Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM), Energy Dispersive X-ray spectroscopy (EDX) and Thermogravimetric Analysis (TGA). The photocatalytic activity of ZrO NPs was studied for azo dye by exposing to sunlight. The azo dye was degraded up to 94.58%. Also the ZrO NPs were studied for in vitro cytotoxicity activity against breast cancer cell lines-MCF-7 and evaluated by MTT assay. The cell morphological changes were recorded by light microscope. The cells viability was seen at 500μg/mL when compared against control. Hence the research highlights, that the method was simple, eco-friendly towards environment by phytoremediation activity of the azo dye and cytotoxicity activity against MCF-7 cell lines. Hence the present paper may help to further explore the metal nanoparticle for its potential applications. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. The Pedagogy and Problems of Jane Andrews's "The Seven Little Sisters Who Live on the Round Ball that Floats in the Air" (1861)

    ERIC Educational Resources Information Center

    Tedesco, Laureen

    2006-01-01

    This essay examines the interplay between Jane Andrews's purpose and her pedagogy in "The Seven Little Sisters Who Live on the Round Ball that Floats in the Air." The book demonstrates the teaching strategies she learned at the First State Normal in Massachusetts, moving from what the child knows to new material, engaging the child in…

  8. Pharmacodynamic evaluation of self micro-emulsifying formulation of standardized extract of Lagerstroemia speciosa for antidiabetic activity.

    PubMed

    Agarwal, Vipin Kumar; Amresh, Gupta; Chandra, Phool

    Lagerstroemia speciosa (SEL) leaves are a popular folk medicine for diabetes treatment due to presence of corosolic acid. It has low water solubility resulting poor absorption after oral administration. Self micro-emulsified drug delivery system is the way by which we can improve the oral absorption of drug. The objective of this study was to develop the self micro-emulsifying formulation of standardized extract of SEL leaves and evaluate its pharmacodynamic performance for antidiabetic activity. The SME formulation was prepared by using sefsol-218 as oil, cremophor-EL as surfactant and transcutol-P as co-surfactant. The ratio of surfactant and co-surfactant was determined by pseudoternary phase diagram. SME formulations were characterized for dilution at different pH, self emulsification, optical clarity, globule size and thermodynamic stability. Pharmacodynamic evaluation of formulations was assessed in Wistar rats by using parameters viz. blood glucose level and serum lipid profile. SEL loaded SME formulation was successfully developed by using sefsol-218, cremophor-EL and transcutol-P with a droplet size 23.53 nm. Pharmacodynamic results showed a higher reduction in blood glucose by SME formulation than SEL without SMES respectively at 50 mg/kg dose while reduction produced at dose of 100 mg/kg was found significant and better on 15th day of study. The percentage reduction produced by SME formulation on serum lipid profile was also significant and was more prominent than SEL. This study confirms that the formulation elevates the pharmacodynamic performance of SEL approximately two fold. Copyright © 2017 Transdisciplinary University, Bangalore and World Ayurveda Foundation. Published by Elsevier B.V. All rights reserved.

  9. Does Andrews facial analysis predict esthetic sagittal maxillary position?

    PubMed

    Resnick, Cory M; Daniels, Kimberly M; Vlahos, Maryann

    2018-04-01

    Cephalometric analyses have limited utility in planning maxillary sagittal position for orthognathic surgery. In Six Elements of Orofacial Harmony, Andrews quantified maxillary position relative to forehead projection and angulation and proposed an ideal relationship. The purpose of this study was to investigate the ability of this technique to predict esthetic sagittal maxillary position. Survey study including a male and female with straight facial profiles, normal maxillary incisor angulations, and Angle's Class I. Maxillary position was modified on lateral photographs to create 5 images for each participant with incisor-goal anterior limit line (GALL) distances of -4, -2, 0, +2, and +4 mm. A series of health care professionals and laypeople were asked to rate each photo in order of attractiveness. A total of 100 complete responses were received. Incisor-GALL distances of +4 mm (41%) and +2 mm (40%) were most commonly considered "most esthetic" for the female volunteer (P < .001). For the male volunteer, there were 2 peak "most esthetic" responses: incisor-GALL distances of 0 mm (37%) and -4 mm (32%) (P < .001). Respondents considered maxillary incisor position 2 to 4 mm anterior to GALL most attractive in a woman and 0 to 4 mm posterior to GALL most esthetic in a man. Using these modified target distances, this analysis may be useful for orthognathic surgery planning. Copyright © 2018 Elsevier Inc. All rights reserved.

  10. The post-disaster negative health legacy: pregnancy outcomes in Louisiana after Hurricane Andrew.

    PubMed

    Antipova, Anzhelika; Curtis, Andrew

    2015-10-01

    Disasters and displacement increasingly affect and challenge urban settings. How do pregnant women fare in the aftermath of a major disaster? This paper investigates the effect of pregnancies in disaster situations. The study tests a hypothesis that pregnant women residing in hurricane-prone areas suffer higher health risks. The setting is Louisiana in the Gulf Coast, United States, a state that continually experiences hurricane impacts. The time period for the analysis is three years following the landfall of Hurricane Andrew in 1992. We analysed low birth weight and preterm deliveries before and after landfall, as a whole and by race. Findings support an association between hazards and health of a community and indicate that pregnant women in the affected area, irrespective of race, are more likely to experience preterm deliveries compared to pre-event births. Results suggest there is a negative health legacy impact in Louisiana as a result of hurricane landfall. © 2015 The Author(s). Disasters © Overseas Development Institute, 2015.

  11. Interview: Professor Andrew Feinberg speaks to Epigenomics.

    PubMed

    Feinberg, Andrew

    2009-10-01

    Andrew Feinberg studied mathematics and humanities at Yale University (CT, USA) in the Directed Studies honors program, and he received his BA (1973) and MD (1976) from the accelerated medical program at Johns Hopkins University (MD, USA), as well as an MPH from Johns Hopkins (1981). He performed a postdoctoral fellowship in developmental biology at the University of California, San Diego (UCSD, CA, USA), clinical training in medicine and medical genetics at the University of Pennsylvania (PA, USA) and genetics research with Bert Vogelstein at Johns Hopkins, discovering altered DNA methylation in human cancer. Dr Feinberg continued to perform seminal work in cancer epigenetics as a Howard Hughes investigator at the University of Michigan (MI, USA), discovering human imprinted genes and loss of imprinting in cancer, and the molecular basis of Beckwith-Wiedemann syndrome. He returned to John Hopkins in 1994 as King Fahd Professor of Medicine, Molecular Biology & Genetics and Oncology, and he holds an Adjunct Professorship at the Karolinska Institute in Sweden. Dr Feinberg is Director of the Center for Epigenetics, a National Human Genome Research Institute-designated Center of Excellence in Genome Sciences. The Center is pioneering genome-scale tools in molecular, statistical and epidemiological epigenetics, and is applying them to the study of cancer, neuropsychiatric disease and aging. As part of the center, Dr Feinberg has organized a highly innovative program to bring gifted minority high-school students into genetics and genomics. Dr Feinberg has also invented a number of widely used molecular tools, including random priming. His honors include election to the American Society for Clinical Investigation, the Association of American Physicians, the Institute of Medicine of the National Academy of Sciences, and the American Academy of Arts and Sciences, as well as membership on the ISI most-cited authors list, a MERIT Award of the National Cancer Institute, a

  12. Effects of standard ethanolic extract from Erythrina velutina in acute cerebral ischemia in mice.

    PubMed

    Rodrigues, Francisca Taciana Sousa; de Sousa, Caren Nádia Soares; Ximenes, Naiara Coelho; Almeida, Anália Barbosa; Cabral, Lucas Moraes; Patrocínio, Cláudio Felipe Vasconcelos; Silva, Aline Holanda; Leal, Luzia Kalyne Almeida Moreira; Honório Júnior, José Eduardo Ribeiro; Macedo, Danielle; Vasconcelos, Silvânia Maria Mendes

    2017-12-01

    The objective of this study was to verify a possible neuroprotective effect of the ethanolic extract of Erythrina velutina (EEEV). Male Swiss mice were submitted to transient cerebral ischemia by occlusion of both carotid arteries for 30 min and treated for 5 days with EEEV (200 or 400 mg/kg) or Memantine (MEM) 10 mg/kg, with initiation of treatment 2 or 24 h after Ischemia. On the 6th day after the induction of ischemia, the animals were submitted to evaluation of locomotor activity and memory and then sacrificed. The brains were dissected for the removal of the prefrontal cortex (PFC), hippocampus (HC) and striatum (ST) for determination of amino acid concentrations. In the step down and Y-maze tests, ischemia caused damage to the animals and treatment with EEEV or MEM reversed this effect. The animals submitted to ischemia also showed memory deficit in the object recognition test, an effect that was reverted by EEEV400 and MEM10. Amino acid dosage showed an increase in excitatory amino acid concentrations in the PFC of the ischemic animals and this effect was reversed by the treatment with EEEV400/24H. Regarding the inhibitory amino acids, ischemia caused an increase of taurine in the PFC while treatment with MEM10/24H or EEEV400/24H reversed this effect. In HC, an increase in excitatory amino acids was also observed in ischemiated animals having treatment with EEEV200/2H or EEEV400/24H reversed this effect. Similar effect was also observed in the same area in relation to the inhibitory amino acids with treatment with MEM10/24H or EEEV400/24H. In the ST, ischemia was also able to cause an increase in excitatory amino acids that was reversed more efficiently by the treatments with MEM10/24H and EEEV200. Also in this area, an increase of taurine and GABA was observed and only the treatment with EEEV200/2H showed a reversion of this effect. In view of these findings, EEEV presents a neuroprotective effect possibly due to its action on amino acid

  13. Making a Bad Situation Worse: An Invasive Species Altering the Balance of Interactions between Local Species.

    PubMed

    Mello, Thayná Jeremias; Oliveira, Alexandre Adalardo de

    2016-01-01

    Biological invasions pose a significant threat to biodiversity, especially on oceanic islands. One of the primary explanations for the success of plant invaders is direct suppression of competitors. However, indirect interactions can also be important, although they are often overlooked in studies on biological invasion. The shrub Leucaena leucocephala is a widespread island invader with putative allelopathic effects on the germination and growth of other species. We quantified the impact of Leucaena on plant communities richness on an oceanic Brazilian island and, through nursery experiments, investigated the potential for allelopathic effects on the germination of Erythrina velutina, a native species that is often absent from stands of Leucaena. Additionally, in a manipulative field experiment, we examined the direct and indirect effects (mediated by the native species Capparis flexuosa) of the invader on the development of Erythrina. The species richness in invaded sites was lower than in uninvaded sites, and Capparis was the only native species that was frequently present in invaded sites. In the nursery experiments, we found no evidence that Leucaena affects the germination of Erythrina. In the field experiments, the odds of Erythrina germination were lower in the presence of Leucaena litter, but higher in the presence of Leucaena trees. However, the survival and growth of Erythrina were considerably inhibited by the presence of Leucaena trees. The isolated effect of native Capparis on the germination and growth of Erythrina varied from positive to neutral. However, when Capparis and Leucaena were both present, their combined negative effects on Erythrina were worse than the effect of Leucaena alone, which may be attributed to indirect effects. This study provides the first empirical evidence that the balance of the interactions between native species can shift from neutral/positive to negative in the presence of an exotic species.

  14. Eliciting maize defense pathways aboveground attracts belowground biocontrol agents.

    PubMed

    Filgueiras, Camila Cramer; Willett, Denis S; Pereira, Ramom Vasconcelos; Moino Junior, Alcides; Pareja, Martin; Duncan, Larry W

    2016-11-04

    Plant defense pathways mediate multitrophic interactions above and belowground. Understanding the effects of these pathways on pests and natural enemies above and belowground holds great potential for designing effective control strategies. Here we investigate the effects of aboveground stimulation of plant defense pathways on the interactions between corn, the aboveground herbivore adult Diabrotica speciosa, the belowground herbivore larval D. speciosa, and the subterranean ento-mopathogenic nematode natural enemy Heterorhabditis amazonensis. We show that adult D. speciosa recruit to aboveground herbivory and methyl salicylate treatment, that larval D. speciosa are relatively indiscriminate, and that H. amazonensis en-tomopathogenic nematodes recruit to corn fed upon by adult D. speciosa. These results suggest that entomopathogenicnematodes belowground can be highly attuned to changes in the aboveground parts of plants and that biological control can be enhanced with induced plant defense in this and similar systems.

  15. Enhancing breast projection in autologous reconstruction using the St Andrew's coning technique and 3D volumetric analysis.

    PubMed

    Chae, Michael P; Rozen, Warren Matthew; Patel, Nakul Gamanlal; Hunter-Smith, David J; Ramakrishnan, Venkat

    2017-12-01

    An increasing number of women undergo mastectomy for breast cancer and post-mastectomy autologous breast reconstruction has been shown to significantly improve the psychosexual wellbeing of the patients. A goal of treatment is to achieve symmetry and projection to match the native breast, and/or the contralateral breast in the case of a unilateral reconstruction. Autologous reconstruction, particularly with the deep inferior epigastric artery perforator (DIEP) flap, is particularly advantageous as it can be manipulated to mimic the shape and turgor of the native breast. However, very few techniques of shaping the breast conus when insetting the DIEP flap to enhance aesthetic outcome have been reported to date. With the aide of three-dimension (3D) photography and 3D-printed mirrored image of the contralateral breast as a guide intraoperatively, we describe our St Andrew's coning technique to create a personalized flap projection. We report a prospective case series of 3 delayed unilateral breast reconstructions where symmetrization procedure to the contralateral breast was not indicated. Using a commercial 3D scanner (VECTRA XR, Canfield Scientific), the breast region was imaged. The mirrored image was 3D-printed in-house using a desktop 3D printer. In all cases, projection of the breast mound was able to be safely achieved, with a demonstrated central volume (or 'cone') able to be highlighted on imaging and a 3D printed breast. A 3D print of the contralateral breast was able to be used intraoperatively to guide the operative approach. The St Andrew's coning technique is a useful aesthetic maneuver for achieving breast projection during DIEP flap breast reconstruction, with 3D imaging techniques able to assist in perioperative assessment of breast volume.

  16. Utilizing NASA Earth Observations to Assess Impacts of Hurricanes Andrew and Irma on Mangrove Forests in Biscayne Bay National Park, FL

    NASA Astrophysics Data System (ADS)

    Kumar, A.; Weber, S.; Remillard, C.; Escobar Pardo, M. L.; Hashemi Tonekaboni, N.; Cameron, C.; Linton, S.; Rickless, D.; Rivero, R.; Madden, M.

    2017-12-01

    Extreme weather events, such as hurricanes, pose major threats to coastal communities around the globe. However, mangrove forests along coastlines act as barriers and subdue the impacts associated with these catastrophic events. The Biscayne Bay National Park mangrove forest located near the city of Miami Beach was recently affected by the category four hurricane Irma in September of 2017. This study analyzed the impact of Hurricane Irma on Biscayne Bay National Park mangroves. Several remote sensing datasets including Landsat 8 Operational Land Imager (OLI), Sentinel 2-Multi Spectral Imager (MSI), PlanetScope, and aerial imagery were utilized to assess pre-and post-hurricane conditions. The high-resolution aerial imagery and PlanetScope data were used to map damaged areas within the national park. Additionally, Landsat 8 OLI and Sentinel-2 MSI data were utilized to estimate changes in biophysical parameters, including gross primary productivity (GPP), before and after Hurricane Irma. This project also examined damages associated with Hurricane Andrew (1992) using historical Landsat 5 Thematic Mapper (TM) data. These results were compared to GPP estimates following Hurricane Irma and suggested that Hurricane Andrew's impact was greater than that of Irma in Biscayne Bay National Park. The results of this study will help to enhance the mangrove health monitoring and shoreline management programs led by officials at the City of Miami Beach Public Works Department.

  17. Mitragyna speciosa Leaf Extract Exhibits Antipsychotic-Like Effect with the Potential to Alleviate Positive and Negative Symptoms of Psychosis in Mice

    PubMed Central

    Vijeepallam, Kamini; Pandy, Vijayapandi; Kunasegaran, Thubasni; Murugan, Dharmani D.; Naidu, Murali

    2016-01-01

    In this study, we investigated the antipsychotic-like effect of methanolic extract of Mitragyna speciosa leaf (MMS) using in vivo and ex vivo studies. In vivo studies comprised of apomorphine-induced climbing behavior, haloperidol-induced catalepsy, and ketamine-induced social withdrawal tests in mice whereas the ex vivo study was conducted utilizing isolated rat vas deferens preparation. Acute oral administration of MMS (50–500 mg/kg) showed an inverted bell-shaped dose-response in apomorphine-induced cage climbing behavior in mice. The effective inhibitory doses of MMS (75 and 100 mg/kg, p.o.) obtained from the apomorphine study was further tested on haloperidol (subcataleptic dose; 0.1 mg/kg, i.p.)-induced catalepsy in the mouse bar test. MMS (75 and 100 mg/kg, p.o.) significantly potentiated the haloperidol-induced catalepsy in mice. Interestingly, MMS at the same effective doses (75 and 100 mg/kg, p.o.) significantly facilitated the social interaction in ketamine-induced social withdrawal mice. Furthermore, MMS inhibited the dopamine-induced contractile response dose-dependently in the isolated rat vas deferens preparations. In conclusion, this investigation provides first evidence that MMS exhibits antipsychotic-like activity with potential to alleviate positive as well as negative symptoms of psychosis in mice. This study also suggests the antidopaminergic activity of MMS that could be responsible for alleviating positive symptoms of psychosis. PMID:27999544

  18. Subterranean termites in urban forestry: tree preference and management.

    PubMed

    Zorzenon, F J; Campos, A E C

    2015-04-01

    Urban tree deterioration is a common problem all over the world. Inappropriate plant species choice and inadequate planting may lead to micro and macro organism attacks, such as pests and diseases. Subterranean termite damage is common and may promote tree falls. In order to help urban forestry planning, this work was carried out for 9 years on 1477 street trees in a neighborhood in the city of São Paulo, Brazil. Plants were identified to species, grouped as native, exotic plants, and palm trees, and their measures of circumference at breast height (CBH) were taken, in order to evaluate if subterranean termite damages are related to tree size and plant group. Four subterranean termite species were identified infesting up to 27% of the plants, with Coptotermes gestroi (Wasmann) being the most common. Palm trees were not damaged by subterranean termites, while native plants are the most susceptible, especially Caesalpinia pluviosa var. peltophoroides (Fabaceae). Among the native plants monitored C. pluviosa var. peltophoroides, Caesalpinia ferrea var. leiostachya, Erythrina speciosa, Piptadenia gonoacantha (Fabaceae), Gochnatia polymorpha (Asteraceae), Tibouchina granulosa (Melastomataceae), and Handroanthus spp. (Bignoniaceae), the latter was the least damaged. Exotic plants were also susceptible with the exception of Lagerstroemia indica (Lythraceae) and Platanus acerifolia (Platanaceae). Correlation analysis showed that the higher the CBH value, the higher the percentage of internal damage by C. gestroi. Infested trees were treated with imidacloprid and thiamethoxam, and subterranean termites were effectively controlled during the 9-year study.

  19. Impact of the newly arrived seed-predating beetle Specularius impressithorax (Coleoptera: Chrysomelidae: Bruchinae) in Hawai'i

    USGS Publications Warehouse

    Medeiros, A.C.; Von Allmen, E.; Fukada, M.; Samuelson, A.; Lau, T.

    2008-01-01

    Prior to 2001, seed predation was virtually absent in the endemic Wiliwili Erythrina sandwicensis (Fabaceae: Degener), dominant tree species of lower-elevation Hawaiian dryland forests. The African bruchine chrysomelid Specularius impressithorax (Pic) (Coleoptera: Chrysomelidae: Bruchinae) was first detected in Hawai'i in 2001 and became established on all main islands within the next two years. The mode of entry for this invasive Erythrina seed predator into Hawai'i is unknown, but likely occurred with the importation of trinket jewelry from Africa containing characteristically brightly-colored Erythrina seeds. The initial establishment of this insect likely occurred on a non-native host, the widely cultivated coral tree E. variegata. Within three years of its first record, S. impressithorax accounted for 77.4% mean seed crop loss in 12 populations of Wiliwili on six main Hawaiian islands. Specularius impressithorax, dispersed through international commerce and established via E. variegata, has become a threat to a unique Hawaiian forest type and may threaten other Erythrina, especially New World representatives.

  20. Business closure and relocation: a comparative analysis of the Loma Prieta earthquake and Hurricane Andrew.

    PubMed

    Wasileski, Gabriela; Rodríguez, Havidán; Diaz, Walter

    2011-01-01

    The occurrence of a number of large-scale disasters or catastrophes in recent years, including the Indian Ocean tsunami (2004), the Kashmir earthquake (2005), Hurricane Katrina (2005) and Hurricane Ike (2008), have raised our awareness regarding the devastating effects of disasters on human populations and the importance of developing mitigation and preparedness strategies to limit the consequences of such events. However, there is still a dearth of social science research focusing on the socio-economic impact of disasters on businesses in the United States. This paper contributes to this research literature by focusing on the impact of disasters on business closure and relocation through the use of multivariate logistic regression models, specifically focusing on the Loma Prieta earthquake (1989) and Hurricane Andrew (1992). Using a multivariate model, we examine how physical damage to the infrastructure, lifeline disruption and business characteristics, among others, impact business closure and relocation following major disasters. © 2011 The Author(s). Disasters © Overseas Development Institute, 2011.

  1. Alpinumisoflavone and abyssinone V 4'-methylether derived from Erythrina lysistemon (Fabaceae) promote HDL-cholesterol synthesis and prevent cholesterol gallstone formation in ovariectomized rats.

    PubMed

    Mvondo, Marie A; Njamen, Dieudonné; Kretzschmar, Georg; Imma Bader, Manuela; Tanee Fomum, Stephen; Wandji, Jean; Vollmer, Günter

    2015-07-01

    Erythrina lysistemon was found to improve lipid profile in ovariectomized rats. Alpinumisoflavone (AIF) and abyssinone V 4'-methylether (AME) derived from this plant induced analogous effects on lipid profile and decreased atherogenic risks. To highlight the molecular mechanism of action of these natural products, we evaluated their effects on the expression of some estrogen-sensitive genes associated with cholesterol synthesis (Esr1 and Apoa1) and cholesterol clearance (Ldlr, Scarb1 and Cyp7a1). Ovariectomized rats were subcutaneously treated for three consecutive days with either compound at the daily dose of 0.1, 1 and 10 mg/kg body weight (BW). Animals were sacrificed thereafter and their liver was collected. The mRNA of genes of interest was analysed by quantitative real-time polymerase chain reaction. Both compounds downregulated the mRNA expression of Esr1, a gene associated with cholesterogenesis and cholesterol gallstone formation. AME leaned the Apoa1/Scarb1 balance in favour of Apoa1, an effect promoting high-density lipoprotein (HDL)-cholesterol formation. It also upregulated the mRNA expression of Ldlr at 1 mg/kg/BW per day (25%) and 10 mg/kg/BW per day (133.17%), an effect favouring the clearance of low-density lipoprotein (LDL)-cholesterol. Both compounds may also promote the conversion of cholesterol into bile acids as they upregulated Cyp7a1 mRNA expression. AIF and AME atheroprotective effects may result from their ability to upregulate mechanisms promoting HDL-cholesterol and bile acid formation. © 2015 Royal Pharmaceutical Society.

  2. Following "the Roots" of Kratom (Mitragyna speciosa): The Evolution of an Enhancer from a Traditional Use to Increase Work and Productivity in Southeast Asia to a Recreational Psychoactive Drug in Western Countries.

    PubMed

    Cinosi, Eduardo; Martinotti, Giovanni; Simonato, Pierluigi; Singh, Darshan; Demetrovics, Zsolt; Roman-Urrestarazu, Andres; Bersani, Francesco Saverio; Vicknasingam, Balasingam; Piazzon, Giulia; Li, Jih-Heng; Yu, Wen-Jing; Kapitány-Fövény, Máté; Farkas, Judit; Di Giannantonio, Massimo; Corazza, Ornella

    2015-01-01

    The use of substances to enhance human abilities is a constant and cross-cultural feature in the evolution of humanity. Although much has changed over time, the availability on the Internet, often supported by misleading marketing strategies, has made their use even more likely and risky. This paper will explore the case of Mitragyna speciosa Korth. (kratom), a tropical tree used traditionally to combat fatigue and improve work productivity among farm populations in Southeast Asia, which has recently become popular as novel psychoactive substance in Western countries. Specifically, it (i) reviews the state of the art on kratom pharmacology and identification; (ii) provides a comprehensive overview of kratom use cross-culturally; (iii) explores the subjective experiences of users; (iv) identifies potential risks and side-effects related to its consumption. Finally, it concludes that the use of kratom is not negligible, especially for self-medication, and more clinical, pharmacological, and socioanthropological studies as well as a better international collaboration are needed to tackle this marginally explored phenomenon.

  3. Occurrence of Cucumber mosaic virus on vanilla (Vanilla planifolia Andrews) in India.

    PubMed

    Madhubala, R; Bhadramurthy, V; Bhat, A I; Hareesh, P S; Retheesh, S T; Bhai, R S

    2005-06-01

    Cucumber mosaic virus (CMV) causing mosaic, leaf distortion and stunting of vanilla (Vanilla planifolia Andrews) in India was characterized on the basis of biological and coat protein (CP) nucleotide sequence properties. In mechanical inoculation tests, the virus was found to infect members of Chenopodiaceae, Cucurbitaceae, Fabaceae and Solanaceae. Nicotiana benthamiana was found to be a suitable host for the propagation of CMV. The virus was purified from inoculated N. benthamiana plants and negatively stained purified preparations contained isometric particles of about 28 nm in diameter. The molecular weight of the viral coat protein subunits was found to be 25.0 kDa. Polyclonal antiserum was produced in New Zealand white rabbit, immunoglobulin G (IgG) was purified and conjugated with alkaline phosphatase enzyme. Double antibody sandwich-enzyme linked immunosorbent assay (DAS-ELISA) method was standardized for the detection of CMV infection in vanilla plants. CP gene of the virus was amplified using reverse transcriptase-polymerase chain reaction (RT-PCR), cloned and sequenced. Sequenced region contained a single open reading frame of 657 nucleotides potentially coding for 218 amino acids. Sequence analyses with other CMV isolates revealed the greatest identity with black pepper isolate of CMV (99%) and the phylogram clearly showed that CMV infecting vanilla belongs to subgroup IB. This is the first report of occurrence of CMV on V. planifolia from India.

  4. Analysis of medical treatment at a field hospital following Hurricane Andrew, 1992.

    PubMed

    Alson, R; Alexander, D; Leonard, R B; Stringer, L W

    1993-11-01

    To determine what medical care was required of a special operations response team by a community devastated by a major hurricane. Retrospective analysis of 1,544 patient encounter forms generated at a field hospital set up in Homestead, Florida, after Hurricane Andrew in August 1992 and staffed by the special operations response team from Forsyth County, North Carolina. All persons presenting for treatment. One thousand two hundred three adult patients and 336 pediatric patients were seen by the special operations response team. Only five of the injuries treated were due directly to the hurricane, whereas 285 of the treated injuries were sustained during clean-up activities. Most of the care provided was routine medical care denied the citizens due to the loss of their physicians' offices and clinics. Supplies of tetanus toxoid, antibiotics, and insulin were depleted in 24 hours. Resupplying these items and acquiring other medication to refill prescriptions constituted a pressing problem. The primary function of medical personnel responding to an area hit by a major hurricane will be to provide general medical care. Any trauma encountered will be primarily due to clean-up activities and not due to the hurricane itself. Responding medical personnel should plan on providing their own food and water for the first 72 hours and be well stocked with antibiotics, tetanus toxoid, and insulin.

  5. Magnitude and extent of sediment toxicity in four bays of the Florida Panhandle: Pensacola, Choctawhatchee, St. Andrew and Apalachicola. National status and trends program for marine environmental quality: Technical memo

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Long, E.R.; Sloane, G.M.; Carr, R.S.

    1997-10-01

    The toxicity of sediments in Pensacola, Choctawhatcheee, St. Andrew and Apalachicola Bays was determined as part of bioeffects assessments performed by NOAA`s National Status and Trends Program. The objectives of the survey were to determine: (1) the spatial patterns in toxicity throughout each bay, (2) the spatial extent of toxicity throughout and among the bays, (3) the severity of degree of toxicity, and (4) the relationships between chemical contamination and toxicity. The survey was conducted over two years: Pensacola Bay and St. Andrew Bay were sampled in 1993; and Choctawhatchee Bay, Apalachicola Bay and Bayou Chico (a sub-basin of Pensacolamore » Bay) were sampled during 1994. Surficial sediment samples were collected from 123 randomly-chosen locations throughout the five areas. Multiple toxicity tests were conducted on all samples, and chemical analyses were performed on 102 of the 123 samples. Toxicological tests were conducted to determine survival, reproductive success, morphological development, metabolic activity, and genotoxicity; all bays showed toxicity in at least some of the samples.« less

  6. Antibiofilm efficacy of green synthesized graphene oxide-silver nanocomposite using Lagerstroemia speciosa floral extract: A comparative study on inhibition of gram-positive and gram-negative biofilms.

    PubMed

    Kulshrestha, Shatavari; Qayyum, Shariq; Khan, Asad U

    2017-02-01

    Biofilm architecture provides bacteria with enhanced antibiotic resistance, thus raising the need to search for alternative therapies that can inhibit the bacterial colonization. In the present study, we synthesized graphene oxide-silver nanocomposite (GO-Ag) by non-toxic and eco-friendly route using a floral extract of Legistromia speciosa (L.) Pers. The gas chromatography-mass spectrometry (GC-MS) analysis of plant extract revealed the presence of compounds which can simultaneously act as reducing and capping agents. The sub-inhibitory concentrations of synthesized GO-Ag reduced the biofilm formation in both gram-negative (E. cloacae) and gram-positive (S. mutans) bacterial models. Growth curve assay, membrane integrity assay, scanning electron microscopy (SEM) and confocal scanning laser microscopy (CSLM) revealed different mechanisms of biofilm inhibition in E. cloacae and S. mutans. Moreover, quantitative RT-PCR (qRT-PCR) results suggested GO-Ag is acting on S. mutans biofilm formation cascade. Biofilm inhibitory concentrations GO-Ag were also found to be non-toxic against HEK-293 (human embryonic kidney cell line). The whole study highlights the therapeutic potential of GO-Ag to restrain the onset of biofilm formation in bacteria. Copyright © 2016 Elsevier Ltd. All rights reserved.

  7. Distribution and abundance of freshwater polychaetes, Manayunkia speciosa (Polychaeta), in the Great Lakes with a 70-year case history for western Lake Erie

    USGS Publications Warehouse

    Schloesser, Don W.

    2013-01-01

    Manayunkia speciosa has been a taxonomic curiosity for 150 years with little interest until 1977 when it was identified as an intermediate host of a fish parasite (Ceratomyxa shasta) responsible for fish mortalities (e.g., chinook salmon). Manayunkia was first reported in the Great Lakes in 1929. Since its discovery, the taxon has been reported in 50% (20 of 40 studies) of benthos studies published between 1960 and 2007. When found, Manayunkia comprised 2) and Georgian Bay (1790/m2) than in five other areas (mean = 60 to 553/m2) of the lakes. A 70-year history of Manayunkia in western Lake Erie indicates it was not found in 1930, was most abundant in 1961 (mean = 8039, maximum = 67,748/m2), and decreased in successive periods of 1982 (3529, 49,639/m2), 1993 (1876, 25,332/m2), and 2003 (79, 2583/m2). It occurred at 48% of stations in 1961, 58% in 1982, 52% in 1993, and 6% of stations in 2003. In all years, Manayunkia was distributed primarily near the mouth of the Detroit River. Causes for declines in distribution and abundance are unknown, but may be related to pollution-abatement programs that began in the 1970s, and invasion of dreissenid mussels in the late-1980s which contributed to de-eutrophication of western Lake Erie. At present, importance of the long-term decline of Manayunkia in Lake Erie is unknown.

  8. An Analysis and Comparison of Two Short Writings: "Inaugural Address at the University of St. Andrew's" by J.S. Mill and "The University of Utopia" by R.M. Hutchins, Based on Five Criteria.

    ERIC Educational Resources Information Center

    Poirier, Jeannine M.

    Focusing on the concept of education for work vs. education for living, the author presents a comparative analysis of two works on liberal education, each of which was originally delivered orally to university students: "The Inaugural Address at the University of St. Andrew" by John Stuart Mill and "The University of Utopia" by…

  9. The brain and the biology of belief: An interview with Andrew Newberg, MD. Interview by Nancy Nachman-Hunt.

    PubMed

    Newberg, Andrew

    2009-01-01

    Andrew Newberg, MD, is an associate professor in the Department of Radiology, Division of Nuclear Medicine, at the Hospital of the University of Pennsylvania, Philadelphia, with secondary appointments in the Departments of Psychiatry and Religious Studies. He is actively involved in neuroimaging research projects, including the study of the neurophysiological correlates of meditation and other types of complementary therapies. Dr Newberg's research now largely focuses on how brain function is associated with various mental states, in particular, the relationship between brain function and mystical or religious experiences. He has authored several books, including Why God Won't Go Away: Brain Science and the Biology of Belief (Ballantine/Random House, 2001) and coauthor with Eugene G. d'Aquili, MD, of The Mystical Mind: Probing the Biology of Religious Experience (Fortress Press, 1999). His most recent book is How God Changes Your Brain, with coauthor Mark Waldman (Ballantine Books, 2009).

  10. Following “the Roots” of Kratom (Mitragyna speciosa): The Evolution of an Enhancer from a Traditional Use to Increase Work and Productivity in Southeast Asia to a Recreational Psychoactive Drug in Western Countries

    PubMed Central

    Cinosi, Eduardo; Martinotti, Giovanni; Simonato, Pierluigi; Singh, Darshan; Demetrovics, Zsolt; Roman-Urrestarazu, Andres; Bersani, Francesco Saverio; Vicknasingam, Balasingam; Piazzon, Giulia; Li, Jih-Heng; Yu, Wen-Jing; Kapitány-Fövény, Máté; Farkas, Judit; Di Giannantonio, Massimo; Corazza, Ornella

    2015-01-01

    The use of substances to enhance human abilities is a constant and cross-cultural feature in the evolution of humanity. Although much has changed over time, the availability on the Internet, often supported by misleading marketing strategies, has made their use even more likely and risky. This paper will explore the case of Mitragyna speciosa Korth. (kratom), a tropical tree used traditionally to combat fatigue and improve work productivity among farm populations in Southeast Asia, which has recently become popular as novel psychoactive substance in Western countries. Specifically, it (i) reviews the state of the art on kratom pharmacology and identification; (ii) provides a comprehensive overview of kratom use cross-culturally; (iii) explores the subjective experiences of users; (iv) identifies potential risks and side-effects related to its consumption. Finally, it concludes that the use of kratom is not negligible, especially for self-medication, and more clinical, pharmacological, and socioanthropological studies as well as a better international collaboration are needed to tackle this marginally explored phenomenon. PMID:26640804

  11. Cylindric partitions, {{\\boldsymbol{ W }}}_{r} characters and the Andrews-Gordon-Bressoud identities

    NASA Astrophysics Data System (ADS)

    Foda, O.; Welsh, T. A.

    2016-04-01

    We study the Andrews-Gordon-Bressoud (AGB) generalisations of the Rogers-Ramanujan q-series identities in the context of cylindric partitions. We recall the definition of r-cylindric partitions, and provide a simple proof of Borodin’s product expression for their generating functions, that can be regarded as a limiting case of an unpublished proof by Krattenthaler. We also recall the relationships between the r-cylindric partition generating functions, the principal characters of {\\hat{{sl}}}r algebras, the {{\\boldsymbol{ M }}}r r,r+d minimal model characters of {{\\boldsymbol{ W }}}r algebras, and the r-string abaci generating functions, providing simple proofs for each. We then set r = 2, and use two-cylindric partitions to re-derive the AGB identities as follows. Firstly, we use Borodin’s product expression for the generating functions of the two-cylindric partitions with infinitely long parts, to obtain the product sides of the AGB identities, times a factor {(q;q)}∞ -1, which is the generating function of ordinary partitions. Next, we obtain a bijection from the two-cylindric partitions, via two-string abaci, into decorated versions of Bressoud’s restricted lattice paths. Extending Bressoud’s method of transforming between restricted paths that obey different restrictions, we obtain sum expressions with manifestly non-negative coefficients for the generating functions of the two-cylindric partitions which contains a factor {(q;q)}∞ -1. Equating the product and sum expressions of the same two-cylindric partitions, and canceling a factor of {(q;q)}∞ -1 on each side, we obtain the AGB identities.

  12. Nuevos rangos altitudinales para dos especies de la avifauna de Nicaragua

    Treesearch

    M.A. Torrez; Wayne Arendt; I. Castillo

    2015-01-01

    We document the elevational range expansions of two Nicaraguan bird species, scaled pigeon (Patagioenas speciosa) and collared plover (Charadrius collaris). The previously reported elevational range of Patagioenas speciosa was sea level to 600 m. We observed the species in shade coffee at Santa Maura farm at an elevation of 1115 masl. Historically, the second species,...

  13. Public health assessment for Wheeling Disposal Service Company Landfill, Amazonia, Andrew County, Missouri, Region 7, CERCLIS number MOD000830554. Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1999-08-25

    The Wheeling Disposal Service Company, Inc., (Wheeling Disposal) site is a closed municipal and industrial waste landfill, approximately 1 mile southeast of Amazonia, Andrew County, Missouri. On-site shallow groundwater is contaminated with Volatile Organic Compounds (VOCs) (methylene chloride, carbon tetrachloride, trichloroethylene) and metals; however, no one is using that water for potable purposes at present. Isolated farm houses are situated in the vicinity of the site, but the houses that would most likely be affected are connected to the public water system. From the information reviewed, DOH concludes that the Wheeling Disposal site currently poses no apparent public health hazard.more » No exposures are known to be occurring at this time. Potential exposure pathways have been identified, but remedial actions eliminated them.« less

  14. Finding of No Significant Impact and Finding of No Practicable Aleternative for the Environmental Assessment for the 21 Point Enclosed Firing Range at Joint-Base Andrews-Naval Air Facility Washington, Maryland

    DTIC Science & Technology

    2015-03-02

    Corps of Engineers Joint Base Andrews-Naval Air Facility Final EA – Firing Range October 2014 v WSSC Washington Suburban Sanitary Commission...are leaving the site with waste residue still on their skin and uniforms. Per section 7.6.1.7 [Latrines ( Sanitary Facilities)] in ETL 11-18 (Small...served by water, sanitary sewer, and power. A fire hydrant exists on the site, while another hydrant exists at the intersection of the entry road and

  15. Abscisic acid metabolite profiling as indicators of plastic responses to drought in grasses from arid Patagonian Monte (Argentina).

    PubMed

    Cenzano, Ana M; Masciarelli, O; Luna, M Virginia

    2014-10-01

    The identification of hormonal and biochemical traits that play functional roles in the adaptation to drought is necessary for the conservation and planning of rangeland management. The aim of this study was to evaluate the effects of drought on i) the water content (WC) of different plant organs, ii) the endogenous level of abscisic acid (ABA) and metabolites (phaseic acid-PA, dihydrophaseic acid-DPA and abscisic acid conjugated with glucose ester-ABA-GE), iii) the total carotenoid concentration and iv) to compare the traits of two desert perennial grasses (Pappostipa speciosa and Poa ligularis) with contrasting morphological and functional drought resistance traits and life-history strategies. Both species were subjected to two levels of gravimetric soil moisture (the highest near field capacity during autumn-winter and the lowest corresponding to summer drought). Drought significantly increased the ABA and DPA levels in the green leaves of P. speciosa and P. ligularis. Drought decreased ABA in the roots of P. speciosa while it increased ABA in the roots of P. ligularis. P. ligularis had the highest ABA level and WC in green leaves. While P. speciosa had the highest DPA levels in leaves. In conclusion, we found the highest ABA level in the mesophytic species P. ligularis and the lowest ABA level in the xerophytic species P. speciosa, revealing that the ABA metabolite profile in each grass species is a plastic response to drought resistance. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  16. The work of Andrew Weil and Deepak Chopra--two holistic health/New Age gurus: a critique of the holistic health/New Age movements.

    PubMed

    Baer, Hans A

    2003-06-01

    Despite the popular roots of the holistic health/New Age movements, a growing number of biomedical physicians have become proponents of holistic health as well as New Age healing. Over the past two decades, Andrew Weil and Deepak Chopra, two biomedically trained physicians, have emerged as the visible and financially successful spokespersons of the movement. This article provides brief biographical sketches of Weil and Chopra and compares and contrasts their respective views on health, illness, healing, and health care. It also considers the response of various biomedical parties to these holistic health/New Age gurus who have attempted to integrate biomedicine and various alternative healing and metaphysical systems. Finally, this article argues that Weil and Chopra both epitomize the limitations of the holistic health/New Age movements, albeit in different ways.

  17. Genetic fidelity of long-term micropropagated shoot cultures of vanilla (Vanilla planifolia Andrews) as assessed by molecular markers.

    PubMed

    Sreedhar, Reddampalli V; Venkatachalam, Lakshmanan; Bhagyalakshmi, Neelwarne

    2007-08-01

    Occurrence of genetic variants during micropropagation is occasionally encountered when the cultures are maintained in vitro for long period. Therefore, the micropropagated multiple shoots of Vanilla planifolia Andrews developed from axillary bud explants established 10 years ago were used to determine somaclonal variation using random amplified polymorphic DNA (RAPD) and intersimple sequence repeats markers (ISSR). One thousand micro-plants were established in soil of which 95 plantlets (consisting of four phenotypes) along with the mother plant were subjected to genetic analyses using RAPD and ISSR markers. Out of the 45 RAPD and 20 ISSR primers screened, 30 RAPD and 7 ISSR primers showed 317 clear, distinct and reproducible band classes resulting in a total of 30 115 bands. However, no difference was observed in banding patterns of any of the samples for a particular primer, indicating the absence of variation among the micropropagated plants. Our results allow us to conclude that the micropropagation protocol that we have used for in vitro proliferation of vanilla plantlets for the last 10 years might be applicable for the production of clonal plants over a considerable period of time.

  18. Wind damage effects of Hurricane Andrew on mangrove communities along the southwest coast of Florida, USA

    USGS Publications Warehouse

    Doyle, T.W.; Smith, T. J.; Robblee, M.B.

    1995-01-01

    On August 24, 1992, Hurricane Andrew downed and defoliated an extensive swath of mangrove trees across the lower Florida peninsula. Permanent field sites were established to assess the extent of forest damage and to monitor the rate and process of forest recovery. Canopy trees suffered the highest mortality particularly for sites within and immediately north of the storm's eyewall. The type and extent of site damage, windthrow, branch loss, and defoliation generally decreased exponentially with increasing distance from the storm track. Forest damage was greater for sites in the storm's right quadrant than in the left quadrant tor the same given distance from the storm center. Stand exposure, both horizontally and vertically, increased the susceptibility and probability of forest damage and accounted for much of the local variability. Slight species differences were found. Laguncularia racemosa exceeded Avicennia germinans and Rhizophora mangle in damage tendency under similar wind conditions. Azimuths of downed trees were strongly correlated with maximum wind speed and vector based on a hurricane simulation of the storm. Lateral branch loss and leaf defoliation on sites without windthrow damage indicated a degree of crown thinning and light penetration equivalent to treefall gaps under normally intact forest conditions. Mangrove species and forests are susceptible to catastrophic disturbance by hurricanes; the impacts of which are significant to changes in forest structure and function.

  19. Ethnobotanical survey and antibacterial activity of some plants used in Guinean traditional medicine.

    PubMed

    Magassouba, F B; Diallo, A; Kouyaté, M; Mara, F; Mara, O; Bangoura, O; Camara, A; Traoré, S; Diallo, A K; Zaoro, M; Lamah, K; Diallo, S; Camara, G; Traoré, S; Kéita, A; Camara, M K; Barry, R; Kéita, S; Oularé, K; Barry, M S; Donzo, M; Camara, K; Toté, K; Berghe, D Vanden; Totté, J; Pieters, L; Vlietinck, A J; Baldé, A M

    2007-10-08

    A total of 418 healers have been interviewed in Guinea, a coastal country of West Africa, ranging between 7 degrees 30 and 12 degrees 30 of northern latitude and 8 degrees and 15 degrees of western longitude. Plant species used by the local inhabitants to treat infectious diseases were identified using ethnobotanical, ethnographic and taxonomic methods. During these investigations, 218 plants were registered, of which the following were the most frequently used: Erythrina senegalensis, Bridelia ferruginea, Crossopteryx febrifuga, Ximenia americana, Annona senegalensis, Cochlospermum tinctorium, Cochlospermum planchonii, Lantana camara, Costus afer, Psidium guajava, Terminalia glaucescens, Uapaca somon and Swartzia madagascariensis. Most plants, and especially the leaves, were essentially used as a decoction. In order to assess antibacterial activity, 190 recipes were prepared and biologically tested, among which six showed activity (minimal inhibitory concentration<125 microg/ml) against Bacillus cereus, Mycobacterium fortuitum, Staphylococcus aureus, or Candida albicans, i.e., Entada africana, Chlorophora regia, Erythrina senegalensis, Harrisonia abyssinica, Uvaria tomentosa, and a mixture of six plants consisting of Swartzia madagascariensis, Isoberlinia doka, Annona senegalensis, Gardenia ternifolia, Terminalia glaucescens and Erythrina senegalensis.

  20. Enrico Fermi Awards Ceremony for Dr. Allen J. Bard and Dr. Andrew Sessler, February 2014 (Presentations, including remarks by Energy Secretary, Dr. Ernest Moniz)

    ScienceCinema

    Moniz, Ernest; Dehmer, Patricia

    2018-05-04

    The Fermi Award is a Presidential award and is one of the oldest and most prestigious science and technology honors bestowed by the U.S. Government. On February 3, 2014 it was conferred upon two exceptional scientists. The first to be recognized is Dr. Allen J. Bard, 'for international leadership in electrochemical science and technology, for advances in photoelectrochemistry and photocatalytic materials, processes, and devices, and for discovery and development of electrochemical methods including electrogenerated chemiluminescence and scanning electrochemical microscopy.' The other honoree is Dr. Andrew Sessler, 'for advancing accelerators as powerful tools of scientific discovery, for visionary direction of the research enterprise focused on challenges in energy and the environment, and for championing outreach and freedom of scientific inquiry worldwide.' Dr. Patricia Dehmer opened the ceremony, and Dr. Ernest Moniz presented the awards.

  1. Physiology and Anatomy for Nurses and Healthcare Practitioners: A Homeostatic Approach - Third edition Clancy John McVicar Andrew J Physiology and Anatomy for Nurses and Healthcare Practitioners: A Homeostatic Approach - Third edition 768pp Hodder Arnold 9780340967591 0340967595 [Formula: see text].

    PubMed

    2010-02-10

    John Clancy and Andrew McVicar give a fascinating insight into the homeostatic mechanism for health. The content focuses on the body's adaptive responses in health and the maladaptive processes in ill-health. In turn, these processes are linked to the knowledge required by healthcare professionals in restoring health or enhancing the quality of life until death.

  2. A survey of culturable aerobic and anaerobic marine bacteria in de novo biofilm formation on natural substrates in St. Andrews Bay, Scotland.

    PubMed

    Finnegan, Lucy; Garcia-Melgares, Manuel; Gmerek, Tomasz; Huddleston, W Ryan; Palmer, Alexander; Robertson, Andrew; Shapiro, Sarah; Unkles, Shiela E

    2011-10-01

    This study reports a novel study of marine biofilm formation comprising aerobic and anaerobic bacteria. Samples of quartz and feldspar, minerals commonly found on the earth, were suspended 5 m deep in the North Sea off the east coast of St. Andrews, Scotland for 5 weeks. The assemblage of organisms attached to these stones was cultivated under aerobic and anaerobic conditions in the laboratory. Bacteria isolated on Marine Agar 2216 were all Gram-negative and identified to genus level by sequencing the gene encoding 16S rRNA. Colwellia, Maribacter, Pseudoaltermonas and Shewanella were observed in aerobically-grown cultures while Vibrio was found to be present in both aerobic and anaerobic cultures. The obligate anaerobic bacterium Psychrilyobacter atlanticus, a recently defined genus, was identified as a close relative of isolates grown anaerobically. The results provide valuable information as to the main players that attach and form de novo biofilms on common minerals in sea water.

  3. Enrico Fermi Awards Ceremony for Dr. Allen J. Bard and Dr. Andrew Sessler, February 2014 (Presentations, including remarks by Energy Secretary, Dr. Ernest Moniz)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moniz, Ernest; Dehmer, Patricia

    The Fermi Award is a Presidential award and is one of the oldest and most prestigious science and technology honors bestowed by the U.S. Government. On February 3, 2014 it was conferred upon two exceptional scientists. The first to be recognized is Dr. Allen J. Bard, 'for international leadership in electrochemical science and technology, for advances in photoelectrochemistry and photocatalytic materials, processes, and devices, and for discovery and development of electrochemical methods including electrogenerated chemiluminescence and scanning electrochemical microscopy.' The other honoree is Dr. Andrew Sessler, 'for advancing accelerators as powerful tools of scientific discovery, for visionary direction of themore » research enterprise focused on challenges in energy and the environment, and for championing outreach and freedom of scientific inquiry worldwide.' Dr. Patricia Dehmer opened the ceremony, and Dr. Ernest Moniz presented the awards.« less

  4. Effects of supplementing Erythrina brucei leaf as a substitute for cotton seed meal on growth performance and carcass characteristics of Sidama goats fed basal diet of natural grass hay.

    PubMed

    Yinnesu, Asmamaw; Nurfeta, Ajebu

    2012-03-01

    The replacement value of dried Erythrina brucei leaf for cotton seed meal (CSM) on growth performance and carcass characteristics was evaluated. Twenty-five yearling buck goats (15.8 ± 1.4 kg) were assigned into five treatments in a randomized complete block design: natural grass hay alone (T1) or supplemented with 100% CSM (T2), 67% CSM + 33% E. brucei (T3), 33% CSM + 67% E. brucei (T4), and 100% E. brucei (T5) on dry matter (DM) basis. Supplemented goats consumed more (P < 0.05) total DM and organic matter (OM) than the non-supplemented group, but the intakes were not influenced (P > 0.05) by the proportion of the supplements. The highest (P < 0.05) crude protein (CP) intake was observed in goats supplemented with CSM alone, whereas the lowest intake was observed in the non-supplemented group. Total CP intake decreased (P < 0.05) with increasing levels of E. brucei in the supplement mixture. The supplemented goats gained more (P < 0.05) weight than the control group. Apparent DM and OM digestibility was higher (P < 0.05) in supplemented goats than in the non-supplemented ones, but similar (P > 0.05) among the supplemented group. The digestibility of CP was higher (P < 0.05) for supplemented goats, except in those goats fed E. brucei alone, than the non-supplemented group. Slaughter weight, empty body weight, hot carcass weight, dressing percentage, rib eye muscle area, and total edible offals were higher (P < 0.05) for supplemented goats than for the non-supplemented ones. It could be concluded that E. brucei could be used as a substitute to CSM under smallholder production systems.

  5. On remembering and forgetting our autobiographical pasts: retrograde amnesia and Andrew Mayes's contribution to neuropsychological method.

    PubMed

    Kopelman, M D; Bright, P

    2012-11-01

    Andrew Mayes's contribution to the neuropsychology of memory has consisted in steadily teasing out the nature of the memory deficit in the amnesic syndrome. This has been done with careful attention to matters of method at all stages. This particularly applies to his investigations of forgetting rates in amnesia and to his studies of retrograde amnesia. Following a brief outline of his work, the main current theories of retrograde amnesia are considered: consolidation theory, episodic-to-semantic shift theory, and multiple trace theory. Findings across the main studies in Alzheimer dementia are reviewed to illustrate what appears to be consistently found, and what is much more inconsistent. A number of problems and issues in current theories are then highlighted--including the nature of the temporal gradient, correlations with the extent of temporal lobe damage, what we would expect 'normal' remote memory curves to look like, how they would appear in focal retrograde amnesia, and whether we can pinpoint retrograde amnesia to hippocampal/medial temporal damage on the basis of existing studies. A recent study of retrograde amnesia is re-analysed to demonstrate temporal gradients on recollected episodic memories in hippocampal/medial temporal patients. It is concluded that there are two requirements for better understanding of the nature of retrograde amnesia: (i) a tighter, Mayesian attention to method in terms of both the neuropsychology and neuroimaging in investigations of retrograde amnesia; and (ii) acknowledging that there may be multiple factors underlying a temporal gradient, and that episodic and semantic memory show important interdependencies at both encoding and retrieval. Such factors may be critical to understanding what is remembered and what is forgotten from our autobiographical pasts. Copyright © 2012 Elsevier Ltd. All rights reserved.

  6. Effects of an alkaloid-rich extract from Mitragyna speciosa leaves and fluoxetine on sleep profiles, EEG spectral frequency and ethanol withdrawal symptoms in rats.

    PubMed

    Cheaha, Dania; Keawpradub, Niwat; Sawangjaroen, Kitja; Phukpattaranont, Pimpimol; Kumarnsit, Ekkasit

    2015-10-15

    Many antidepressants are effective in alleviating ethanol withdrawal symptoms. However, most of them suppress rapid eye movement (REM) sleep. Thus, development of antidepressants without undesirable side effects would be preferable. Previously, crude alkaloid extract from Mitragyna speciosa (MS) Korth was found to produce antidepressant activities. It was hypothesized that the alkaloid extract from MS may attenuate ethanol withdrawal without REM sleep disturbance. Adult male Wistar rats implanted with electrodes over the frontal and parietal cortices were used for two separated studies. For an acute study, 10 mg/kg fluoxetine or 60 mg/kg alkaloid extract from MS were administered intragastrically. Electroencephalographic (EEG) signals were recorded for 3 h to examine sleep profiles and EEG fingerprints. Another set of animal was used for an ethanol withdrawal study. They were rendered dependent on ethanol via a modified liquid diet (MLD) containing ethanol ad libitum for 28 days. On day 29, fluoxetine (10 mg/kg) or alkaloid extract from MS (60 mg/kg) were administered 15 min before the ethanol-containing MLD was replaced with an isocaloric ethanol-free MLD to induced ethanol withdrawal symptoms. The sleep analysis revealed that alkaloid extract from MS did not change any REM parameters which included average duration of each REM episode, total REM time, number of REM episode and REM latency whereas fluoxetine significantly suppressed all REM parameters and delayed REM latency. However, power spectral analysis revealed similar fingerprints for fluoxetine and alkaloid extract from MS characterized by decreasing powers in the slow frequency range in frontal and parietal cortical EEG. Neither treatment affected spontaneous motor activity. Finally, both alkaloid extract from MS and fluoxetine were found to significantly attenuate ethanol withdrawal-induced hyperexcitability (increases gamma activity) in both cortices and to reduce locomotor activity. The present study

  7. Construction, Startup and Operation of a New LLRW Disposal Facility in Andrews County, Texas - 12151

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Van Vliet, James A.

    2012-07-01

    During this last year, Waste Control Specialists LLC (WCS) completed construction and achieved start of operations of a new low level radioactive waste (LLRW) disposal facility in Andrews County Texas. Disposal operations are underway for commercial LLRW, and start up evolutions are in progress for disposal of Department of Energy (DOE) LLRW. The overall approach to construction and start up are presented as well as some of the more significant challenges and how they were addressed to achieve initial operations of the first new commercial low level radioactive waste disposal facility in more than 30 years. The WCS disposal facilitymore » consists of two LLRW disposal cells, one for Texas Compact waste, and a separate disposal cell for DOE waste. Both disposal cells have very robust and unique designs. The cells themselves are constructed entirely in very low permeability red bed clay. The cell liners include a 0.91 meter thick clay liner meeting unprecedented permeability limits, 0.3 meter thick reinforced concrete barriers, as well as the standard geo-synthetic liners. Actions taken to meet performance criteria and install these liners will be discussed. Consistent with this highly protective landfill design, WCS chose to install a zero discharge site water management system. The considerations behind the design and construction of this system will be presented. Other activities essential to successful start of LLRW disposal operations included process and procedure development and refinement, staffing and staff development, and training. Mock ups were built and used for important evolutions and functions. Consistent with the extensive regulation of LLRW operations, engagement with the Texas Commission on Environmental Quality (TCEQ) was continuous and highly interactive. This included daily activity conference calls, weekly coordination calls and numerous topical conference calls and meetings. TCEQ staff and consultants frequently observed specific

  8. Genetic diversity in natural populations of mangaba in Sergipe, the largest producer State in Brazil.

    PubMed

    Soares, A N R; Vitória, M F; Nascimento, A L S; Ledo, A S; Rabbani, A R C; Silva, A V C

    2016-08-19

    Mangaba (Hancornia speciosa Gomes) is found in areas of coastal tablelands in the Brazilian Northeast and Cerrado regions. This species has been subjected to habitat fragmentation that is mainly due to human activity, and requires conservation strategies. The aim of this study was to analyze the structure and inter- and intrapopulation genetic diversity of natural populations of H. speciosa Gomes using inter-simple sequence repeat (ISSR) molecular markers. A total of 155 individuals were sampled in 10 natural populations (ITA, PAC, IND, EST, BC, PIR, JAP, BG, NEO, and SANT) in the State of Sergipe, Brazil. Fifteen primers were used to generate 162 fragments with 100% polymorphism. Genetic analysis showed that the variability between populations (77%) was higher than within populations (23%). It was possible to identify five different groups by the unweighted pair group method with arithmetic mean and principal coordinate analysis, and only one individual (E10) remained isolated. Using ISSR markers it was possible to obtain a molecular profile of the populations evaluated, showing that these markers were effective and exhibited sufficient polymorphism to estimate the genetic variability of natural populations of H. speciosa Gomes.

  9. Book Review: Maxwell's Demon 2: Entropy, classical and quantum information, computing. Harvey Leff and Andrew Rex (Eds.); Institute of Physics, Bristol, 2003, 500pp., US 55, ISBN 0750307595

    NASA Astrophysics Data System (ADS)

    Shenker, Orly R.

    2004-09-01

    In 1867, James Clerk Maxwell proposed a perpetuum mobile of the second kind, that is, a counter example for the Second Law of thermodynamics, which came to be known as "Maxwell's Demon." Unlike any other perpetual motion machine, this one escaped attempts by the best scientists and philosophers to show that the Second Law or its statistical mechanical counterparts are universal after all. "Maxwell's demon lives on. After more than 130 years of uncertain life and at least two pronouncements of death, this fanciful character seems more vibrant than ever." These words of Harvey Leff and Andrew Rex (1990), which open their introduction to Maxwell's Demon 2: Entropy, Classical and Quantum Information, Computing (hereafter MD2) are very true: the Demon is as challenging and as intriguing as ever, and forces us to think and rethink about the foundations of thermodynamics and of statistical mechanics.

  10. Molecular analysis of abnormal hemoglobins in beta chain in Aegean region of Turkey and first reports of hemoglobin Andrew-Minneapolis and Hb Hinsdale from Turkey.

    PubMed

    Aykut, Ayça; Onay, Hüseyin; Durmaz, Asude; Karaca, Emin; Vergin, Canan; Aydınok, Yeşim; Özkınay, Ferda

    2015-07-01

    The Agean is one of the regions in Turkey where thalassemias and abnormal hemoglobins (Hbs) are prevalent. Combined heterozygosity of thalassemia mutations with a variety of structural Hb variants lead to an extremely wide spectrum of clinical and hematological phenotypes which is of importance for prenatal diagnosis. One hundred and seventeen patients and carriers diagnosed by hemoglobin electrophoresis (HPLC), at risk for abnormal hemoglobinopathies were screened for mutational analysis of the beta-globin gene. The full coding the 5' UTR, and the 3' UTR sequences of beta-globin gene (GenBank accession no. U01317) were amplified and sequenced. In this study, a total of 118 (12.24%) structural Hb variant alleles were identified in 1341 mutated beta-chain alleles in Medical Genetics Department of Ege University between January 2006 and November 2013. Here, we report the mutation spectrum of abnormal Hbs associated with the beta-globin gene in Aegean region of Turkey. In the present study, the Hb Hinsdale and Hb Andrew-Minneapolis variants are demonstrated for the first time in the Turkish population.

  11. Developing an assessment of fire-setting to guide treatment in secure settings: the St Andrew's Fire and Arson Risk Instrument (SAFARI).

    PubMed

    Long, Clive G; Banyard, Ellen; Fulton, Barbara; Hollin, Clive R

    2014-09-01

    Arson and fire-setting are highly prevalent among patients in secure psychiatric settings but there is an absence of valid and reliable assessment instruments and no evidence of a significant approach to intervention. To develop a semi-structured interview assessment specifically for fire-setting to augment structured assessments of risk and need. The extant literature was used to frame interview questions relating to the antecedents, behaviour and consequences necessary to formulate a functional analysis. Questions also covered readiness to change, fire-setting self-efficacy, the probability of future fire-setting, barriers to change, and understanding of fire-setting behaviour. The assessment concludes with indications for assessment and a treatment action plan. The inventory was piloted with a sample of women in secure care and was assessed for comprehensibility, reliability and validity. Staff rated the St Andrews Fire and Risk Instrument (SAFARI) as acceptable to patients and easy to administer. SAFARI was found to be comprehensible by over 95% of the general population, to have good acceptance, high internal reliability, substantial test-retest reliability and validity. SAFARI helps to provide a clear explanation of fire-setting in terms of the complex interplay of antecedents and consequences and facilitates the design of an individually tailored treatment programme in sympathy with a cognitive-behavioural approach. Further studies are needed to verify the reliability and validity of SAFARI with male populations and across settings.

  12. Evaluation of Hydraulically Significant Discontinuities in Dockum Group Mudrocks in Andrews County, Texas

    NASA Astrophysics Data System (ADS)

    Holt, R. M.; Kuszmaul, J. S.; Cao, S.; Powers, D. W.

    2013-12-01

    Triassic mudrocks of the Dockum Group (Cooper Canyon Formation) host four, below-grade landfills at the Waste Control Specialists (WSC) site in Andrews County, Texas, including: a hazardous waste landfill and three radioactive waste landfills. At the study site, the Dockum consists of mudrocks with sparse siltstone/sandstone interbeds that developed in a semi-arid environment from an ephemeral meandering fluvial system. Sedimentary studies reveal that the mudrocks are ancient floodplain vertisols (soils with swelling clays) and siltstone/sandstone interbeds are fluvial channel deposits that were frequently subaerially exposed. Rock discontinuities, including fractures and syndepositional slickensided surfaces, were mapped during the excavation of the WCS radioactive waste landfills along vertical faces prepared by the construction contractor. Face locations were selected to insure a sampled area with nearly complete vertical coverage for each landfill. Individual discontinuities were mapped and their strike, dip, length, roughness, curvature, staining, and evidence of displacement were described. In the three radioactive waste disposal landfills, over 1750 discontinuities across 35 excavated faces were mapped and described, where each face was nominally 8 to 10 ft tall and 50 to 100 ft long. Genetic units related to paleosol development were identified. On average, the orientation of the discontinuities was horizontal, and no other significant trends were observed. Mapping within the landfill excavations shows that most discontinuities within Dockum rocks are horizontal, concave upward, slickensided surfaces that developed in the depositional environment, as repeated wetting and drying cycles led to shrinking and swelling of floodplain vertisols. Fractures that showed staining (a possible indicator of past or present hydraulic activity) are rare, vertical to near-vertical, and occur mainly in, and adjacent to, mechanically stiff siltstone and sandstone interbeds

  13. Andrew's Law

    THOMAS, 113th Congress

    Sen. Schumer, Charles E. [D-NY

    2013-11-21

    Senate - 11/21/2013 Read twice and referred to the Committee on Health, Education, Labor, and Pensions. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  14. Hydrologic and forest management controls on DOC dynamics in the small watersheds of the H.J. Andrews Experimental Forest, OR

    NASA Astrophysics Data System (ADS)

    Lajtha, K.; Jones, J. A.

    2016-12-01

    Dissolved organic carbon (DOC) export from hillslopes to streams is an important component of the carbon cycle of a catchment and may be a critical source of energy for the aquatic food web in receiving waters. Using a long-term record of DOC and other dissolved nutrients and elements from paired watersheds from the H.J. Andrews Experimental Forest in Oregon, we explored hydrologic, climatic, and land-use controls on seasonal and inter-annual patterns of DOC flux in a seasonally dry ecosystem. Seasonal patterns of DOC flux demonstrated source limitations to DOC export, with DOC concentrations highest immediately following the first rains after a dry summer, and lowest after winter rains. In contrast, more geochemically-controlled elements showed simple dilution-concentration patterns with no seasonal hysteresis. Inter-annual patterns of DOC flux, however, did not provide evidence of source limitation, with DOC flux within a watershed tightly correlated to total discharge but not temperature. Among watersheds, forest harvest, even over 50 years ago, significantly reduced DOC flux but not fluxes of other elements including N; this response was linked to the loading of coarse woody debris to the forest floor. Chemical fingerprinting of DOC revealed that old-growth watersheds had higher fluxes of DOC characteristic of forest floor organic materials, likely delivered to streams through more surficial preferential flow pathways not subject to microbial alteration, respiration, or sorption losses. Taken together these results suggest that the biogeochemical composition of forested streams reflects both current hydrologic patterns and also processes that occurred many decades ago within the catchment.

  15. Integration of a Miniaturized Conductivity Sensor into an Animal-borne Instrument

    DTIC Science & Technology

    2014-09-30

    animal-borne instrument Lars Boehme Sea Mammal Research Unit Scottish Oceans Institute University of St Andrews St Andrews, KY16 8LB United...NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) University of St Andrews, Scottish Oceans Institute,Sea Mammal Research Unit,St Andrews

  16. Sir Henry Solomon Wellcome and Dr Andrew Balfour: an enterprise on the Nile and the early foundation of public health and medical research in the Sudan (1899-1935).

    PubMed

    Elhadd, T A

    2015-01-01

    In Sudan, modern medical practice and medical research began soon after the creation of Anglo-Egyptian Sudan at the turn of the 20th century. The benevolent involvement of Sir Henry Solomon Wellcome, and the ingenious feat of his protégé Sir Andrew Balfour, was crucial to the strong foundation of that establishment. Sir Henry Wellcome provided the financial sponsorship plus influential, logistical and moral support. Dr Balfour put great energy into making the enterprise one of the most amazing medical achievements in colonial medicine. Improvement in the public health of the capital Khartoum was emulated by other doctors working in this vast country. Research was not restricted to tropical medicine; it also encompassed agricultural and chemical research. This helped with the establishment of the first modern medical school in the country in 1924 and resulted in the medical service in Sudan being described as one of the best in the world. Many British doctors flocked to Sudan to make a fortune and to set a path for their career back in Britain.

  17. 75 FR 6020 - Notice of Competing Preliminary Permit Applications Accepted for Filing and Soliciting Comments...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-05

    ... feasibility of the George W. Andrews Hydroelectric Project located at the existing George W. Andrews Lock and.... Andrews Lock and Dam Hydroelectric Project by Brookfield Power (Project No. 13077-000, filed on November... have an average annual generation of 89 gigawatt-hours. The proposed George W. Andrews Hydroelectric...

  18. Flood of September 7-9, 1987, in Lexington and Richland counties in the vicinity of Saint Andrews Road and Irmo, South Carolina

    USGS Publications Warehouse

    Guimaraes, W.B.

    1989-01-01

    Localized heavy rainfall on September 7, 1987, in Lexington and Richland Counties, South Carolina, caused severe flooding in the basins of Kinley Creek, Rawls Creek, and Stoop Creek, in the vicinity of Saint Andrews Road and the town of Irmo, South Carolina. The flooding damaged homes, furnishings, and landscaping. Rainfall, peak discharges, high-water elevations, and frequency relations of rainfall and discharge are tabulated and plotted for selected streams. The rain was most intense in the area along Rawls Creek, R-2 (tributary to Rawls Creek), Koon Branch (tributary to Rawls Creek), and the upper part of Kinley Creek. A rainfall of about 5.5 inches in 3 hours, which has a recurrence interval in excess of 100 years, was reported by local residents along these streams. High-water marks are presented in this report for Stoop Creek, Kinley Creek, K-1 (tributary to Kinley Creek), K-2 (tributary to Kinley Creek), unnamed tributary to Kinley Creek, Lowery Creek (tributary to Kinley Creek), Rawls Creek, R-2 (tributary to Rawls Creek), and Koon Branch (tributary to Rawls Creek). Peak discharges at the most downstream sites on Rawls Creek and Koon Branch had recurrence intervals of 75 years and 60 years, respectively. Peak discharges on Kinley Creek varied from 20 to 25 years north of K-1 basin to less than 10 years at K-1. The Stoop Creek basin had a recurrence interval of 10 years. (USGS)

  19. Occurrence of Squash yellow mild mottle virus and Pepper golden mosaic virus in Potential New Hosts in Costa Rica

    PubMed Central

    Castro, Ruth M.; Moreira, Lisela; Rojas, María R.; Gilbertson, Robert L.; Hernández, Eduardo; Mora, Floribeth; Ramírez, Pilar

    2013-01-01

    Leaf samples of Solanum lycopersicum, Capsicum annuum, Cucurbita moschata, Cucurbita pepo, Sechium edule and Erythrina spp. were collected. All samples were positive for begomoviruses using polymerase chain reaction and degenerate primers. A sequence of ∼1,100 bp was obtained from the genomic component DNA-A of 14 samples. In addition, one sequence of ∼580 bp corresponding to the coat protein (AV1) was obtained from a chayote (S. edule) leaf sample. The presence of Squash yellow mild mottle virus (SYMMoV) and Pepper golden mosaic virus (PepGMV) were confirmed. The host range reported for SYMMoV includes species of the Cucurbitaceae, Caricaceae and Fabaceae families. This report extends the host range of SYMMoV to include the Solanaceae family, and extends the host range of PepGMV to include C. moschata, C. pepo and the Fabaceae Erythrina spp. This is the first report of a begomovirus (PepGMV) infecting chayote in the Western Hemisphere. PMID:25288955

  20. Occurrence of Squash yellow mild mottle virus and Pepper golden mosaic virus in Potential New Hosts in Costa Rica.

    PubMed

    Castro, Ruth M; Moreira, Lisela; Rojas, María R; Gilbertson, Robert L; Hernández, Eduardo; Mora, Floribeth; Ramírez, Pilar

    2013-09-01

    Leaf samples of Solanum lycopersicum, Capsicum annuum, Cucurbita moschata, Cucurbita pepo, Sechium edule and Erythrina spp. were collected. All samples were positive for begomoviruses using polymerase chain reaction and degenerate primers. A sequence of ∼1,100 bp was obtained from the genomic component DNA-A of 14 samples. In addition, one sequence of ∼580 bp corresponding to the coat protein (AV1) was obtained from a chayote (S. edule) leaf sample. The presence of Squash yellow mild mottle virus (SYMMoV) and Pepper golden mosaic virus (PepGMV) were confirmed. The host range reported for SYMMoV includes species of the Cucurbitaceae, Caricaceae and Fabaceae families. This report extends the host range of SYMMoV to include the Solanaceae family, and extends the host range of PepGMV to include C. moschata, C. pepo and the Fabaceae Erythrina spp. This is the first report of a begomovirus (PepGMV) infecting chayote in the Western Hemisphere.

  1. Andrew Ferguson | NREL

    Science.gov Websites

    molecular organic semiconductors under the supervision of Prof. Tim Jones in the Centre for Electronic as a postdoctoral researcher, investigating the fate of excitons and carriers in organic photovoltaic in nanoscale and organic semiconductors. Research Interests Tailored Carbon Nanotube Thermoelectric

  2. Andrew Norman | NREL

    Science.gov Websites

    MOCVD grown InP-based materials and a LINK project involving TEM studies of non-planar and localized . M. Jones, Appl. Phys. Lett. 93 (2008) 123505. "Theoretical and experimental examination of the

  3. National Airspace Review. Change 1.

    DTIC Science & Technology

    1985-01-01

    Horn Ausociation (NBAAI Regional Air)ine Association (RAAI Martin Macy Martin Macv Martin Macy Expenmental Aircraft Asao atlon (EAAI Andrew Procop ...Andrew Procop Andrew Procop Helicooter Association Internationl (HAl) Glenn Leister Vernice Robichaud Glenn Lester Air Traffic Control Association. Inc

  4. KENNEDY SPACE CENTER, FLA. - STS-114 Mission Specialist Andrew Thomas is pleased to be back at KSC after arriving aboard a T-38 jet aircraft. He and other crew members are at the Center for familiarization activities with equipment. The mission is Logistics Flight 1, scheduled to deliver to the Space Station the external stowage platform and the Multi-Purpose Logistics Module with supplies and equipment.

    NASA Image and Video Library

    2004-03-05

    KENNEDY SPACE CENTER, FLA. - STS-114 Mission Specialist Andrew Thomas is pleased to be back at KSC after arriving aboard a T-38 jet aircraft. He and other crew members are at the Center for familiarization activities with equipment. The mission is Logistics Flight 1, scheduled to deliver to the Space Station the external stowage platform and the Multi-Purpose Logistics Module with supplies and equipment.

  5. Unravelling the role of host plant expansion in the diversification of a Neotropical butterfly genus.

    PubMed

    McClure, Melanie; Elias, Marianne

    2016-06-16

    Understanding the processes underlying diversification is a central question in evolutionary biology. For butterflies, access to new host plants provides opportunities for adaptive speciation. On the one hand, locally abundant host species can generate ecologically significant selection pressure. But a diversity of host plant species within the geographic range of each population and/or species might also eliminate any advantage conferred by specialization. This paper focuses on four Melinaea species, which are oligophagous on the family Solanaceae: M. menophilus, M. satevis, M. marsaeus, and finally, M. mothone. We examined both female preference and larval performance on two host plant species that commonly occur in this butterfly's native range, Juanulloa parasitica and Trianaea speciosa, to determine whether the different Melinaea species show evidence of local adaptation. In choice experiments, M. mothone females used both host plants for oviposition, whereas all other species used J. parasitica almost exclusively. In no choice experiment, M. mothone was the only species that readily accepted T. speciosa as a larval host plant. Larval survival was highest on J. parasitica (82.0 % vs. 60.9 %) and development took longer on T. speciosa (14.12 days vs. 13.35 days), except for M. mothone, which did equally well on both host plants. For all species, average pupal weight was highest on J. parasitica (450.66 mg vs. 420.01 mg), although this difference was least apparent in M. mothone. We did not find that coexisting species of Melinaea partition host plant resources as expected if speciation is primarily driven by host plant divergence. Although M. mothone shows evidence of local adaptation to a novel host plant, T. speciosa, which co-occurs, it does not preferentially lay more eggs on or perform better on this host plant than on host plants used by other Melinaea species and not present in its distributional range. It is likely that diversification in this

  6. Evaluation of in vitro absorption, distribution, metabolism, and excretion (ADME) properties of mitragynine, 7-hydroxymitragynine, and mitraphylline

    USDA-ARS?s Scientific Manuscript database

    Mitragyna speciosa (Kratom) is a popular herb in Southeast Asia which is traditionally used to treat withdrawal symptoms associated with opiate addiction. Mitragynine, 7-hydroxymitragynine and mitraphylline are reported to be the central nervous system (CNS) active alkaloids which bind to the opiat...

  7. 76 FR 70423 - Procurement List Proposed Additions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-14

    ..., Joint Base Andrews Naval Air Facility Washington, 1500 West Perimeter Road, Suite 2780, Joint Base Andrews, MD. NPA: Blind Industries & Services of Maryland, Baltimore, MD, Contracting Activity: Dept of the Air Force, FA2860 11 Cons Lgc, Andrews AFB, MD. Patricia Briscoe, Deputy Director, Business...

  8. Small-scale variations of climate change in mountainous forested terrain - a regional study from H.J. Andrews Long Term Ecological Research site in Oregon, USA

    NASA Astrophysics Data System (ADS)

    Honzakova, Katerina; Hoffmann, Peter; Jones, Julia; Thomas, Christoph

    2017-04-01

    There has been conflicting evidence as to whether high elevations are experiencing more pronounced climate warming than lower elevations in mountainous regions. In this study we analyze temperature records from H.J. Andrews Long Term Ecological Research, Oregon, USA and several nearby areas, comprising together 28 stations located in Cascade Mountains. The data, starting in 1958, are first checked for quality and homogenized using the Standard Normal Homogeneity Test. As a reference, composite climate time series based on the Global Historic Climate Network is created and together with cross-referencing against station records used to correct breaks and shifts in the data. In the next step, we investigate temperature patterns of the study site from 1958 to 2016 and compare them for valley and hill stations. In particular, we explore seasonality and inter-annual variability of the records and trends of the last day of frost. Additionally, 'cold' sums (positive and negative) are calculated to obtain a link between temperature and ecosystems' responses (such as budbreaks). So far, valley stations seem to be more prone to climate change than ridge or summit stations, contrary to current thinking. Building on previous knowledge, we attempt to provide physical explanations for the temperature records, focusing on wind patterns and associated phenomena such as cold air drainage and pooling. To aid this we analyze wind speed and direction data available for some of the stations since 1996, including seasonality and inter-annual variability of the observed flows.

  9. Longevity of crapemyrtle pollen stored at different temperatures

    USDA-ARS?s Scientific Manuscript database

    Temperatures for storage of crapemyrtle (Lagerstroemia app.) pollen over time were studied using clones of two interspecific hybrids (L. 'Cheyenne' and L. 'Wichita') and five species (L. indica 'Catawba', L. subcostata (NA 40181), L. limii, L. speciosa, and L. fauriei 'Kiowa'). Pollen samples were s...

  10. The navel orangeworm, Amyelois transtilla (Walker) (Lepidoptera: Pyralidae) discovered in northeastern Mexico feeding on Sapindaceae

    USDA-ARS?s Scientific Manuscript database

    Amyelois transitella (Walker) (Lepidoptera: Pyralidae), the navel orangeworm, is an important pest of a wide variety fruits and their seeds. We discovered and report for the first time A. transitella feeding on Sapindaceae in wild populations of U. speciosa (Endl.) in northeastern Mexico. We provid...

  11. 75 FR 5341 - Classification and Conveyance for Recreation and Public Purposes Act of Public Lands in Harney...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-02

    ... lands by close of business on March 4, 2010. ADDRESSES: Mail written comments to Joan M. Suther, Andrews... property. The conveyance of this parcel is consistent with the BLM Andrews Management Unit Resource... or other delivery services, or hand-delivered to the Andrews/Steens Field Manager, BLM Burns District...

  12. On five species of the tribes Abacetini and Pterostichini (Coleoptera, Carabidae)

    PubMed Central

    Guéorguiev, Borislav V.

    2013-01-01

    Abstract Metabacetus willi sp. n. (type locality: Indonesia, Central Java Province, Purworejo Regency, Kaligesing District, cave Seplawan near Donorejo) and Rhytiferonia beroni sp. n. (type locality: Papua New Guinea, West Sepik Province, Bonforok bil, Tifalmin, 1600 m) are described. Two new combinations: Poecilus (Ancholeus) campania (Andrewes, 1937), comb. n. of Feronia campania Andrewes, 1937, Aristochroa poecilma (Andrewes, 1937), comb. n. of Feronia poecilma Andrewes, 1937, and a new synonymy: Pterostichus (Oreophilus) podgoricensis B. Guéorguiev, 2013, syn. n. of Pterostichus (Oreophilus) flavofemoratus pinguis (Dejean, 1828), are proposed, too. PMID:24294091

  13. 77 FR 14965 - Special Local Regulations; Red Bull Candola, New River, Fort Lauderdale, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-14

    ... on the waters of the New River between the Esplanade Park and slightly east of the South Andrews... waters of the New River between Esplanade Park and slightly east of the South Andrews Avenue Bascule.... All waters of the New River between the Esplanade Park and slightly east of the South Andrews Avenue...

  14. Phylogenetic systematics of Schacontia Dyar with descriptions of eight new species (Lepidoptera, Crambidae)

    PubMed Central

    Goldstein, Paul Z.; Metz, Mark A.; Solis, M. Alma

    2013-01-01

    Abstract The Neotropical genus Schacontia Dyar (1914) is reviewed and revised to include eleven species. Schacontia replica Dyar, 1914, syn. n. and Schacontia pfeifferi Amsel, 1956, syn. n. are synonymized with Schacontia chanesalis (Druce, 1899) and eight new species are described: Schacontia umbra,sp. n., Schacontia speciosa,sp. n., Schacontia themis, sp. n., Schacontia rasa, sp. n., Schacontia nyx,sp. n., Schacontia clotho, sp. n., Schacontia lachesis, sp. n., and Schacontia atropos, sp. n. Three species, Schacontia medalba, Schacontia chanesalis, and Schacontia ysticalis, are re-described. An analysis of 64 characters (56 binary, 8 multistate; 5 head, 13 thoracic, 13 abdominal, 25 male genitalic, and 8 female genitalic) scored for all Schacontia and three outgroup species (Eustixia pupula Hübner, 1823, Glaphyria sesquistrialis Hübner, 1823, and Hellula undalis (Fabricius, 1781)) retrieved 8 equally most parsimonious trees (L=102, CI=71, RI=84) of which the strict consensus is: [[[[medalba + umbra] + chanesalis] + speciosa] + [ysticalis + [rasa + themis + [atropos + lachesis + nyx + clotho

  15. A Multi-Week Behavioral Sampling Tag for Sound Effects Studies: Design Trade-Offs and Prototype Evaluation

    DTIC Science & Technology

    2012-09-30

    Doug Gillespie, SMRU/U. St. Andrews Mark Johnson, SMRU/U. St. Andrews Holger Klink, U. Oregon Phil Lovell , SMRU/U. St. Andrews David Mann, U. South...be be sourced from an ’ AA ’ size Lithium primary (non- rechargable) cell while the tag is attached to an animal and then from a rechargeable Lithium-ion

  16. Strength and Fatigue of NT551 Silicon Nitride and NT551 Diesel Exhaust Valves

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Andrews, M.J.; Wereszczak, A.A.; Kirkland, T.P.

    2000-02-01

    The content of this report is excerpted from Mark Andrew's Ph.D. Thesis (Andrews, 1999), which was funded by a DOEYOTT High Temperature Materials Laboratory Graduate Fellowship. It involves the characterization of NT551 and valves fabricated with it. Greater detail of the described issues may be found in that reference or through communications with Andrew Wereszczak.

  17. KENNEDY SPACE CENTER, FLA. - STS-114 Mission Specialists Andrew Thomas and Soichi Noguchi look at the leading edge of Discovery’s wing with RCC panels removed. Noguchi is with the Japanese Aerospace and Exploration Agency. Crew members are at KSC becoming familiar with Shuttle and mission equipment. The mission is Logistics Flight 1, which is scheduled to deliver supplies and equipment plus the external stowage platform to the International Space Station.

    NASA Image and Video Library

    2004-03-05

    KENNEDY SPACE CENTER, FLA. - STS-114 Mission Specialists Andrew Thomas and Soichi Noguchi look at the leading edge of Discovery’s wing with RCC panels removed. Noguchi is with the Japanese Aerospace and Exploration Agency. Crew members are at KSC becoming familiar with Shuttle and mission equipment. The mission is Logistics Flight 1, which is scheduled to deliver supplies and equipment plus the external stowage platform to the International Space Station.

  18. Phylogenetic analysis, genetic diversity and relationships between the recently segregated species of Corynandra and Cleoserrata from the genus Cleome using DNA barcoding and molecular markers.

    PubMed

    Tamboli, Asif Shabodin; Patil, Swapnil Mahadeo; Gholave, Avinash Ramchandra; Kadam, Suhas Kishor; Kotibhaskar, Shreya Vijaykumar; Yadav, Shrirang Ramchandra; Govindwar, Sanjay Prabhu

    2016-01-01

    Cleome is the largest genus in the family Cleomaceae and it is known for its various medicinal properties. Recently, some species from the Cleome genus (Cleome viscosa, Cleome chelidonii, Cleome felina and Cleome speciosa) are split into genera Corynandra (Corynandra viscosa, Corynandra chelidonii, Corynandra felina), and Cleoserrata (Cleoserrata speciosa). The objective of this study was to obtain DNA barcodes for these species for their accurate identification and determining phylogenetic relationships. Out of 10 screened barcoding regions, rbcL, matK and ITS1 regions showed higher PCR efficiency and sequencing success. This study added matK, rbcL and ITS1 barcodes for the identification of Corynandra chelidonii, Corynandra felina, Cleome simplicifolia and Cleome aspera species in existing barcode data. Corynandra chelidonii and Corynandra felina species belong to the Corynandra genus, but they are not grouped with the Corynandra viscosa species, however clustered with the Cleome species. Molecular marker analysis showed 100% polymorphism among the studied plant samples. Diversity indices for molecular markers were ranged from He=0.1115-0.1714 and I=0.2268-0.2700, which indicates a significant amount of genetic diversity among studied species. Discrimination of the Cleome and Corynandra species from Cleoserrata speciosa was obtained by two RAPD primers (OPA-4 and RAPD-17) and two ISSR primers (ISSR-1 and ISSR-2). RAPD and ISSR markers are useful for the genetic characterization of these studied species. The present investigation will be helpful to understand the relationships of Cleome lineages with Corynandra and Cleoserrata species. Copyright © 2016 Académie des sciences. Published by Elsevier SAS. All rights reserved.

  19. Novel synthetic products from the common milkweed (Asclepias syriaca L) and their potential in the rural farm economy

    USDA-ARS?s Scientific Manuscript database

    The common milkweed is of the family Asclepiadaceae which comprises over 200 genera and 2500 species including Asclepias syriaca L and its near relatives, A. speciosa and A. tuberosa. Asclepias syriaca, or the common milkweed, is a perennial that is native to the Americas and is so named because of...

  20. Modeling & Testing of Inflatable Structures for Rapidly Deployable Port Infrastructures

    DTIC Science & Technology

    2010-07-01

    Rapidly Deployable Port Infrastructures By: Andrew Bloxom Abel Medellin Chris Vince Dr. Solomon Yim N SW C C D -C IS D -2 01...Andrew Bloxom, Abel Medellin , Chris Vince, Dr. Solomon Yim 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING...Andrew Bloxom Abel Medellin Chris Vince Dr. Solomon Yim A special thanks to: • Ben Testerman and Dr. Pat

  1. Model-Based Clustering and Data Transformations for Gene Expression Data

    DTIC Science & Technology

    2001-04-30

    transformation parameters, e.g. Andrews, Gnanadesikan , and Warner (1973). Aitchison tests: Aitchison (1986) tested three aspects of the data for...N in the Box-Cox transformation in Equation (5) is estimated by maximum likelihood using the observa- tions (Andrews, Gnanadesikan , and Warner 1973...Compositional Data. Chapman and Hall. Andrews, D. F., R. Gnanadesikan , and J. L. Warner (1973). Methods for assessing multivari- ate normality. In P. R

  2. A comparison of mercury burdens between St. Marks National Wildlife Refuge and St. Andrew Bay, Florida: Evaluation of fish body burdens and physiological responses in largemouth bass, spotted seatrout, striped mullet, and sunfish

    USGS Publications Warehouse

    Huge, D.H.; Rauschenberger, R.H.; Wieser, F.M.; Hemming, J.M.

    2011-01-01

    Musculature from the dorsal region of 130 largemouth bass (Micropterus salmoides), 140 sunfish (Lepomis sp.), 41 spotted seatrout (Cynoscion nebulosus) and 67 striped mullet (Mugil cephalus) were collected from five estuarine and five freshwater sites within the St. Marks National Wildlife Refuge and two estuarine and two freshwater sites from St. Andrew Bay, Florida, United States of America. Musculature was analyzed for total mercury content, sagittal otoliths were removed for age determination and physiological responses were measured. Largemouth bass and sunfish from the refuge had higher mercury concentrations in musculature than those from the bay. Male spotted seatrout, male striped mullet, male and female sunfish and female largemouth bass had mercury burdens positively correlated with length. The majority of all four species of fish from both study areas contained mercury levels below 1.5 part per million, the limit for safe consumption recommended the Florida Department of Health. In comparison, a significant percentage of largemouth bass and sunfish from several sampled sites, most notably Otter Lake and Lake Renfroe within St. Marks National Wildlife Refuge, had mercury levels consistent with the health department's guidelines of 'limited consumption' or 'no consumption guidelines.'

  3. A Survey of Work-Related Attitudes among the Employee Groups of the United States Army Dental Activity, Fort Lewis, Washington.

    DTIC Science & Technology

    1981-04-01

    78), pp. 127-131. 61bid. 7John Ivancevich, Andrew D. Szilagyi , and Marc J. Wallace , Organizational Behavior and Performance, (Santa Monica: Goodyear...Ivancevich, John, Szilagyi , Andrew D., and Wallace , Marc J. Organ- izational Behavior and Performance. Santa Monica: Goodyear Publishing Co., 1977. Kendler... Szilagyi , Andrew D., Sims, Henry P., and Terrill, Robert C. "The Relationship of Leadership Style to Employee Job Satisfaction." Hospital and Health

  4. CTC Sentinel. Volume 9, Issue 3

    DTIC Science & Technology

    2016-03-01

    International Terror Andrew Watkins 19 The Islamic State Threat to Britain: Evidence from Recent Terror Trials Raffaello Pantucci PROFILE 24 The Last...a new beachhead for fostering the Islamic State’s regional extremism.” Andrew Watkins explores why there may be a strong correlation between...offensive Andrew Watkins is an energy and security analyst for the Iraq Oil Report. He spent four years working as a senior lecturer at the American

  5. Integration of a Miniaturized Conductivity Sensor into an Animal-Borne Instrument

    DTIC Science & Technology

    2015-09-30

    an Animal -Borne Instrument Lars Boehme Sea Mammal Research Unit Scottish Oceans Institute University of St Andrews St Andrews, KY16 8LB United... Kingdom phone: +44 1334-462677 fax: +44 1334-463443 email: lb284@st-andrews.ac.uk Robin Pascal Sensors Development Group National...Oceanography Centre Southampton, SO14 3ZY United Kingdom phone: +44 2380-596138 fax: +44 2380-593029 email: rwp@nerc.ac.uk Phil Lovell

  6. George Andrew Olah - Patents

    Science.gov Websites

    Additional Information US 4,394,247 LIQUEFACTION OF COALS USING RECYCLABLE SUPERACID CATALYST - Olah, George catalytic condensation using superacid catalysts. US 4,465,893 OXIDATIVE CONDENSATION OF NATURAL GAS OR ., synthetic transportation fuels or lower olefins) via catalytic condensation using superacid catalysts. US

  7. Interview: Andrew S. Garrison.

    ERIC Educational Resources Information Center

    Williamson, J. W.

    1995-01-01

    Andy Garrison, an award-winning independent filmmaker, discusses his association with the Dayton (OH) Community Media Workshop and with Appalshop, the eastern Kentucky media arts center. His interests lie in making films that suggest political or social statements as evidenced in his most recent films, Fat Monroe and Night Shift, which depict…

  8. Evaluation of the Cardiotoxicity of Mitragynine and Its Analogues Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

    PubMed Central

    Wu, Jianjun; Jamil, Mohd Fadzly Amar; Tan, Mei Lan; Adenan, Mohd Ilham; Wong, Philip; Shim, Winston

    2014-01-01

    Introduction Mitragynine is a major bioactive compound of Kratom, which is derived from the leave extracts of Mitragyna speciosa Korth or Mitragyna speciosa (M. speciosa), a medicinal plant from South East Asia used legally in many countries as stimulant with opioid-like effects for the treatment of chronic pain and opioid-withdrawal symptoms. Fatal incidents with Mitragynine have been associated with cardiac arrest. In this study, we determined the cardiotoxicity of Mitragynine and other chemical constituents isolated using human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). Methods and Results The rapid delayed rectifier potassium current (I Kr), L-type Ca2+ current (I Ca,L) and action potential duration (APD) were measured by whole cell patch-clamp. The expression of KCNH2 and cytotoxicity was determined by real-time PCR and Caspase activity measurements. After significant I Kr suppression by Mitragynine (10 µM) was confirmed in hERG-HEK cells, we systematically examined the effects of Mitragynine and other chemical constituents in hiPSC-CMs. Mitragynine, Paynantheine, Speciogynine and Speciociliatine, dosage-dependently (0.1∼100 µM) suppressed I Kr in hiPSC-CMs by 67% ∼84% with IC50 ranged from 0.91 to 2.47 µM. Moreover, Mitragynine (10 µM) significantly prolonged APD at 50 and 90% repolarization (APD50 and APD90) (439.0±11.6 vs. 585.2±45.5 ms and 536.0±22.6 vs. 705.9±46.1 ms, respectively) and induced arrhythmia, without altering the L-type Ca2+ current. Neither the expression,and intracellular distribution of KCNH2/Kv11.1, nor the Caspase 3 activity were significantly affected by Mitragynine. Conclusions Our study indicates that Mitragynine and its analogues may potentiate Torsade de Pointes through inhibition of I Kr in human cardiomyocytes. PMID:25535742

  9. Effects of CS Agents on Vegetation. II. Field and Screening Studies

    DTIC Science & Technology

    1974-08-01

    10 Brassica rapa L.. turnip 30-50 50-70 Browallia speciosa Hook., browallia 0-10 10-20 Campanula medium L., Canterbury bells 10-20 20-30 Capsicum ... annuum L., pepper 0-10 0-10 Celosia cristata L.. cockscomb 0-10 10-20 Citrullus vudgaris Schrad., watermelon 10-20 20-30 Cucumis satirus L.. cucumber 0

  10. Chemical diversity in the genus Alpinia (Zingiberaceae): comparative composition of four Alpinia species grown in Northern India.

    PubMed

    Padalia, Rajendra C; Verma, Ram S; Sundaresan, Velusamy; Chanotiya, Chandan S

    2010-08-01

    The essential-oil compositions of leaves, flowers, and rhizomes of Alpinia galanga (L.) Willd., Alpinia calcarata Rosc., Alpinia speciosa K. Schum., and Alpinia allughas Rosc. were examined and compared by capillary GC and GC/MS. Monoterpenoids were the major oil constituents identified. 1,8-Cineole, alpha-terpineol, (E)-methyl cinnamate, camphor, terpinen-4-ol, and alpha- and beta-pinenes were the major constituents commonly distributed in leaf and flower essential oils. The presence of endo-fenchyl acetate, exo-fenchyl acetate, and endo-fenchol was the unique feature of rhizome essential oils of A. galanga, A. calcarata, and A. speciosa. On contrary, the rhizome oil of A. allughas was dominated by beta-pinene. Significant qualitative and quantitative variations were observed in essential-oil compositions of different parts of Alpinia species growing in subtemperate and subtropical regions of Northern India. Cluster analysis was performed to find similarities and differences in essential-oil compositions based on representative molecular skeletons. Monoterpenoids, viz., 1,8-cineole, terpinen-4-ol, camphor, pinenes, (E)-methyl cinnamate, and fenchyl derivatives, were used as chemotaxonomic markers.

  11. From Kratom to mitragynine and its derivatives: physiological and behavioural effects related to use, abuse, and addiction.

    PubMed

    Hassan, Zurina; Muzaimi, Mustapha; Navaratnam, Visweswaran; Yusoff, Nurul H M; Suhaimi, Farah W; Vadivelu, Rajakumar; Vicknasingam, Balasingam K; Amato, Davide; von Hörsten, Stephan; Ismail, Nurul I W; Jayabalan, Nanthini; Hazim, Ammar I; Mansor, Sharif M; Müller, Christian P

    2013-02-01

    Kratom (or Ketum) is a psychoactive plant preparation used in Southeast Asia. It is derived from the plant Mitragyna speciosa Korth. Kratom as well as its main alkaloid, mitragynine, currently spreads around the world. Thus, addiction potential and adverse health consequences are becoming an important issue for health authorities. Here we reviewed the available evidence and identified future research needs. It was found that mitragynine and M. speciosa preparations are systematically consumed with rather well defined instrumentalization goals, e.g. to enhance tolerance for hard work or as a substitute in the self-treatment of opiate addiction. There is also evidence from experimental animal models supporting analgesic, muscle relaxant, anti-inflammatory as well as strong anorectic effects. In humans, regular consumption may escalate, lead to tolerance and may yield aversive withdrawal effects. Mitragynine and its derivatives actions in the central nervous system involve μ-opioid receptors, neuronal Ca²⁺ channels and descending monoaminergic projections. Altogether, available data currently suggest both, a therapeutic as well as an abuse potential. Copyright © 2012 Elsevier Ltd. All rights reserved.

  12. a Preliminary Characterisation of SYMBIODINIUM Diversity in Some Common Corals from Singapore

    NASA Astrophysics Data System (ADS)

    Isa Tanzil, Jani Thuaibah; Ng, Abigayle Pek Kaye; Tey, Yi Qing; Tan, Beverly Hsin Yi; Yun, Eric Yao; Huang, Danwei

    The symbiosis between corals and Symbiodinium dinoflagellates is considered a major driver of the distribution and health of reefs worldwide. This study investigated the genetic identities and diversity of Symbiodinium in seven coral species (Porites lutea, Porites lobata, Acropora millepora, Merulina ampliata, Diploastrea heliopora, Pachyseris speciosa, Pocillopora acuta) from three shallow reefs around Singapore (Kusu Island, Pulau Tekukor, Pulau Satumu). Analyses of 31 colonies using denaturing gradient gel electrophoresis of the nuclear internal transcribed spacer region indicated the dominance of C and D Symbiodinium clades. The latter clade was the predominant symbiont in Pachyseris speciosa collected from Pulau Tekukor but those sampled from Pulau Satumu hosted C27, providing evidence for variable symbiosis in this species. The prevalence of the D clade - noted for their stress tolerance (e.g. to elevated temperatures and sedimentation) - in three of seven coral species examined could underlie the importance of this particular symbiotic relationship for the persistence of Singapore’s impacted reefs. Further characterisation of Symbiodinium communities may provide insights into corals’ response to stress and their bleaching patterns in the future.

  13. 78 FR 23548 - Draft Supplemental Environmental Impact Statement for the Long-Term Management and Storage of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-19

    ... Control Specialists, LLC, site near Andrews, Texas. Since publication of the 2011 Mercury Storage EIS, DOE... identified the Waste Control Specialists, LLC location near Andrews, Texas, as the Preferred Alternative in...

  14. 77 FR 47859 - Proposed Flood Hazard Determinations; Correction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-10

    ... Boulevard, Deerfield Beach, FL 33442. City of Fort Lauderdale City Hall, 100 North Andrews Avenue, Fort..., 115 South Andrews Avenue, Room 409, Fort Lauderdale, FL 33301. Village of Lazy Lake Village Hall, 2250...

  15. Microbial activity, arbuscular mycorrhizal fungi and inoculation of woody plants in lead contaminated soil.

    PubMed

    Gattai, Graziella S; Pereira, Sônia V; Costa, Cynthia M C; Lima, Cláudia E P; Maia, Leonor C

    2011-07-01

    The goals of this study were to evaluate the microbial activity, arbuscular mycorrhizal fungi and inoculation of woody plants (Caesalpinia ferrea, Mimosa tenuiflora and Erythrina velutina) in lead contaminated soil from the semi-arid region of northeastern of Brazil (Belo Jardim, Pernambuco). Dilutions were prepared by adding lead contaminated soil (270 mg Kg(-1)) to uncontaminated soil (37 mg Pb Kg soil(-1)) in the proportions of 7.5%, 15%, and 30% (v:v). The increase of lead contamination in the soil negatively influenced the amount of carbon in the microbial biomass of the samples from both the dry and rainy seasons and the metabolic quotient only differed between the collection seasons in the 30% contaminated soil. The average value of the acid phosphatase activity in the dry season was 2.3 times higher than observed during the rainy season. There was no significant difference in the number of glomerospores observed between soils and periods studied. The most probable number of infective propagules was reduced for both seasons due to the excess lead in soil. The mycorrhizal colonization rate was reduced for the three plant species assayed. The inoculation with arbuscular mycorrhizal fungi benefited the growth of Erythrina velutina in lead contaminated soil.

  16. Microbial activity, arbuscular mycorrhizal fungi and inoculation of woody plants in lead contaminated soil

    PubMed Central

    Gattai, Graziella S.; Pereira, Sônia V.; Costa, Cynthia M. C.; Lima, Cláudia E. P.; Maia, Leonor C.

    2011-01-01

    The goals of this study were to evaluate the microbial activity, arbuscular mycorrhizal fungi and inoculation of woody plants (Caesalpinia ferrea, Mimosa tenuiflora and Erythrina velutina) in lead contaminated soil from the semi-arid region of northeastern of Brazil (Belo Jardim, Pernambuco). Dilutions were prepared by adding lead contaminated soil (270 mg Kg-1) to uncontaminated soil (37 mg Pb Kg soil-1) in the proportions of 7.5%, 15%, and 30% (v:v). The increase of lead contamination in the soil negatively influenced the amount of carbon in the microbial biomass of the samples from both the dry and rainy seasons and the metabolic quotient only differed between the collection seasons in the 30% contaminated soil. The average value of the acid phosphatase activity in the dry season was 2.3 times higher than observed during the rainy season. There was no significant difference in the number of glomerospores observed between soils and periods studied. The most probable number of infective propagules was reduced for both seasons due to the excess lead in soil. The mycorrhizal colonization rate was reduced for the three plant species assayed. The inoculation with arbuscular mycorrhizal fungi benefited the growth of Erythrina velutina in lead contaminated soil. PMID:24031701

  17. Pollen and stigma morphology of some Phaseoleae species (Leguminosae) with different pollinators.

    PubMed

    Basso-Alves, J P; Agostini, K; Teixeira, S de Pádua

    2011-07-01

    Pollen transport to a receptive stigma can be facilitated through different pollinators, which submits the pollen to different selection pressures. This study aimed to associate pollen and stigma morphology with zoophily in species of the tribe Phaseoleae. Species of the genera Erythrina, Macroptilium and Mucuna with different pollinators were chosen. Pollen grains and stigmas were examined under light microscopy (anatomy), scanning electronic microscopy (surface analyses) and transmission electronic microscopy (ultrastructure). The three genera differ in terms of pollen wall ornamentation, pollen size, pollen aperture, thickness of the pollen wall, amount of pollenkitt, pollen hydration status and dominant reserves within the pollen grain, while species within each genus are very similar in most studied characteristics. Most of these features lack relationships to pollinator type, especially in Erythrina and Mucuna. Pollen reserves are discussed on a broad scale, according to the occurrence of protein in the pollen of invertebrate- or vertebrate-pollinated species. Some pollen characteristics are more associated to semi-dry stigma requirements. This apical, compact, cuticularised and secretory stigma occurs in all species investigated. We conclude that data on pollen and stigma structure should be included together with those on floral morphology and pollinator behaviour for the establishment of functional pollination classes. © 2010 German Botanical Society and The Royal Botanical Society of the Netherlands.

  18. Concluding Analysis of IR Measurements of Microbreaking and Whitecaps

    DTIC Science & Technology

    2004-09-30

    Microbreaking and Whitecaps 5b. GRANT NUMBER N00014-02-1-0523 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER Andrew T. Jessup 5e. TASK NUMBER...LIMITATION OF 18. NUMBER 19a. NAME OF RESPONSIBLE PERSON a. REPORT b. ABSTRACT c. THIS PAGE ABSTRACT OF Andrew Jessup PAGES Unclassified Unclassified...N00014-02-0523 Concluding Analysis of IR Measurements of Microbreaking and Whitecaps 04 Apr 2002 through 30 Sep 2004 Andrew T. Jessup Applied Physics

  19. Coastal Storm Surge Analysis: Storm Forcing. Report 3. Intermediate Submission No. 1.3

    DTIC Science & Technology

    2013-07-01

    No. 1.3 C oa st al a n d H yd ra u lic s La b or at or y Peter Vickery, Dhiraj Wadhera, Andrew Cox, Vince Cardone , Jeffrey Hanson, and Brian...Andrew Cox and Vince Cardone Oceanweather, Inc 5 River Road, Suite 1 Cos Cob, CT 06807 Jeffrey L. Hanson Field Research Facility US Army Engineer...Zou Modeling Mesh Modeling Mesh Modeling Mesh Elizabeth City State University Jinchun Yuan Web/GIS Oceanweather Vince Cardone Andrew Cox Wind

  20. NOAA Photo Library - Historic Weather Service/Meteorological

    Science.gov Websites

    Monsters/Hurricanes - Hurricane Andrew NOAA Photo Library Banner Takes you to the Top Page the Links page. Hurricane Andrew Banner Historical Weather Service | Meteorological Monsters 1 2 3 4

  1. 75 FR 77898 - Notice of Inventory Completion: University of Colorado Museum, Boulder, CO

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-14

    ... individual were removed from an unknown location in Wisconsin, by D.M. Andrews. In 1963, Mrs. Walter Steele.... Andrews collection. Officials of the University of Colorado Museum have determined, pursuant to 25 U.S.C...

  2. 75 FR 47808 - Alabama Municipal Electric Authority; Notice of Competing Preliminary Permit Application Accepted...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-09

    ..., proposing to study the feasibility of the George W. Andrews Lock and Dam Hydroelectric Project. The proposed project would be located at the existing George W. Andrews Lock and Dam on the Chattahoochee River in...

  3. 20 CFR 416.1232 - Replacement of lost, damaged, or stolen excluded resources.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    .... Exception: For victims of Hurricane Andrew only, the extension period for good cause may be extended for up... additional extension under the Hurricane Andrew provision) may be extended for a reasonable period up to an...

  4. 20 CFR 416.1232 - Replacement of lost, damaged, or stolen excluded resources.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    .... Exception: For victims of Hurricane Andrew only, the extension period for good cause may be extended for up... additional extension under the Hurricane Andrew provision) may be extended for a reasonable period up to an...

  5. 20 CFR 416.1232 - Replacement of lost, damaged, or stolen excluded resources.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    .... Exception: For victims of Hurricane Andrew only, the extension period for good cause may be extended for up... additional extension under the Hurricane Andrew provision) may be extended for a reasonable period up to an...

  6. 20 CFR 416.1232 - Replacement of lost, damaged, or stolen excluded resources.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    .... Exception: For victims of Hurricane Andrew only, the extension period for good cause may be extended for up... additional extension under the Hurricane Andrew provision) may be extended for a reasonable period up to an...

  7. 20 CFR 416.1232 - Replacement of lost, damaged, or stolen excluded resources.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    .... Exception: For victims of Hurricane Andrew only, the extension period for good cause may be extended for up... additional extension under the Hurricane Andrew provision) may be extended for a reasonable period up to an...

  8. KENNEDY SPACE CENTER, FLA. - Members of the STS-114 crew spend time becoming familiar with Shuttle and mission equipment. From left are Mission Specialists Stephen Robinson, Charles Camarda and Andrew Thomas. On the work stand is the insert for Discovery’s nose cap, which is being fitted with themal protection system insulation blankets. The mission is Logistics Flight 1, which is scheduled to deliver supplies and equipment plus the external stowage platform to the International Space Station.

    NASA Image and Video Library

    2004-03-05

    KENNEDY SPACE CENTER, FLA. - Members of the STS-114 crew spend time becoming familiar with Shuttle and mission equipment. From left are Mission Specialists Stephen Robinson, Charles Camarda and Andrew Thomas. On the work stand is the insert for Discovery’s nose cap, which is being fitted with themal protection system insulation blankets. The mission is Logistics Flight 1, which is scheduled to deliver supplies and equipment plus the external stowage platform to the International Space Station.

  9. KENNEDY SPACE CENTER, FLA. - Members of the STS-114 crew spend time becoming familiar with Shuttle and mission equipment. Mission Specialists Soichi Noguchi (left) and Andrew Thomas (center) look at an engine eyelet, which serves as part of the thermal protection system on an orbiter. Noguchi is with the Japanese Aerospace Exploration Agency (JAXA). The mission is Logistics Flight 1, which is scheduled to deliver supplies and equipment and the external stowage platform to the International Space Station.

    NASA Image and Video Library

    2004-03-05

    KENNEDY SPACE CENTER, FLA. - Members of the STS-114 crew spend time becoming familiar with Shuttle and mission equipment. Mission Specialists Soichi Noguchi (left) and Andrew Thomas (center) look at an engine eyelet, which serves as part of the thermal protection system on an orbiter. Noguchi is with the Japanese Aerospace Exploration Agency (JAXA). The mission is Logistics Flight 1, which is scheduled to deliver supplies and equipment and the external stowage platform to the International Space Station.

  10. Hurricane impacts on the coastal environment

    USGS Publications Warehouse

    Sallenger, Abby

    1990-01-01

    In terms of insured losses, Hurricane Andrew is the most severe catastrophe in the Nation's history. Prior to the arrival of Andrew, the U.S. Geological Survey (USGS), in cooperation with the Louisiana Geological Survey (LGS), acquired an extensive body of information and data on the behavior and long-term erosion of Louisiana barrier islands. As a result, we have a clear understanding of pre-storm conditions in this area; Andrew provided an opportunity to learn in detail the impact of a very large storm on Louisiana coastal environment.

  11. The Hegemony Handbook: Exploiting the Space between War and Peace

    DTIC Science & Technology

    2016-11-01

    2015/11/02/china-lassen-destroyer-spratly-islands- south-china-sea-andrew- erickson -naval-war-college-militia-coast-guard-navy-confrontation...china-lassen-destroyer-spratly-islands-south-china-sea-andrew- erickson -naval-war- college-militia-coast-guard-navy-confrontation-territorial-dispute

  12. 76 FR 13018 - Departmental Offices Proposed Collections; Comment Requests

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-09

    ... U.S.C. 3506(c)(2)(A)). The Consumer Financial Protection Bureau implementation team is soliciting... consideration. ADDRESSES: Direct all written comments to Andrew Trueblood, Consumer Financial Protection Bureau... additional information should be directed to Andrew Trueblood in writing at Consumer Financial Protection...

  13. Offensive Cyber Capability: Can it Reduce Cyberterrorism

    DTIC Science & Technology

    2010-12-02

    33 Lech J. Janczewski, and Andrew M. Colarik, eds., Cyber Warfare and Cyber Terrorism (New York: Information Science Reference, 2008...Science and Business Media, 2008. Janczewski, Lech , J. and Andrew M. Colarik, eds., Cyber Warfare and Cyber Terrorism. New York: Information Science

  14. Cyberspace Dependence in Air Force Flying Squadrons and its Effect on Mission Assurance

    DTIC Science & Technology

    2010-06-01

    book Managerial Guide for Handling Cyber-Terrorism and Information Warfare, Lech Janczewski and Andrew Colarik advocate the need for organizations...of Cyber Operations,” High Frontier, 5(3): 11-15 (May 2009). Janczewski, Lech and Andrew Colarik. Managerial Guide for Handling Cyber

  15. Andrew P. Carpenter Tax Act

    THOMAS, 112th Congress

    Rep. DesJarlais, Scott [R-TN-4

    2012-04-27

    Senate - 09/20/2012 Received in the Senate and Read twice and referred to the Committee on Finance. (All Actions) Tracker: This bill has the status Passed HouseHere are the steps for Status of Legislation:

  16. 76 FR 11764 - Notice of Availability of Government-Owned Inventions; Available for Licensing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-03

    .... Patent No. 7,048,854: Apparatus for the removal of heavy metals from acidic wastewater and chemical... inventions cited should be directed to Andrew Drucker, Naval Facilities Engineering Service Center, Code EV12... INFORMATION CONTACT: Andrew Drucker supporting the Head of Technology Transfer Office, Naval Facilities...

  17. 75 FR 77665 - Whirlpool Corporation, Including On-Site Leased Workers From Career Solutions TEC Staffing and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-13

    ..., Including On-Site Leased Workers From Career Solutions TEC Staffing and Andrews International, Fort Smith... Staffing, Fort Smith, Arkansas. The notice was published in the Federal Register on October 25, 2010 (75 FR... reports that workers leased from Andrews International were employed on-site at the Fort Smith, Arkansas...

  18. The Role of the National Guard in Homeland Security

    DTIC Science & Technology

    2007-05-01

    Fulcrum Publishing, 1996), 19. 22Ibid., 20. 23Thomas Andrew Bailey and Paul B. Ryan, The Lusitania Disaster: An Episode in Modern Warfare and...Bailey, Thomas Andrew, and Paul B. Ryan. The Lusitania Disaster: An Episode in Modern Warfare and Diplomacy. New York, NY: Free Press, 1975. Ball

  19. Technology Counts 2007: A Digital Decade

    ERIC Educational Resources Information Center

    Education Week, 2007

    2007-01-01

    "Technology Counts 2007" looks back, and ahead, after a decade of enormous upheaval in the educational technology landscape. This special issue of "Education Week" includes the following articles: (1) A Digital Decade; (2) Getting Up to Speed (Andrew Trotter); (3) E-Rate's Imprint Seen in Schools (Andrew Trotter); (4) Teaching…

  20. Optically- and Thermally-Responsive Programmable Materials Based on Carbon Nanotube-Hydrogel Polymer Composites

    DTIC Science & Technology

    2011-07-07

    Jamshidi, Kuniharu Takei, Hyunhyub Ko, Andrew Gillies, Rizia Bardhan , Xiaobo Zhang, Jeffrey J. Urban, Ming Wu, Ali Javey, Ronald Fearing, Cary L...Hyunhyub Ko,†,‡,§ Andrew Gillies,† Rizia Bardhan ,|| Jeffrey J. Urban,|| Ming Wu,†,‡ Ronald Fearing,† and Ali Javey*,†,‡,§ †Electrical

  1. Analysis of the Latin Square Task with Linear Logistic Test Models

    ERIC Educational Resources Information Center

    Zeuch, Nina; Holling, Heinz; Kuhn, Jorg-Tobias

    2011-01-01

    The Latin Square Task (LST) was developed by Birney, Halford, and Andrews [Birney, D. P., Halford, G. S., & Andrews, G. (2006). Measuring the influence of cognitive complexity on relational reasoning: The development of the Latin Square Task. Educational and Psychological Measurement, 66, 146-171.] and represents a non-domain specific,…

  2. 76 FR 18934 - Suspension of Community Eligibility

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-06

    ... April 16, 1976, ......do Do. Perry County. Emerg; March 4, 1988, Reg; April 18, 2011, Susp. Fremont... Do. Andrew County. 1976, Emerg; August 24, 1984, Reg; April 18, 2011, Susp. Savannah, City of, Andrew..., Reg; April 18, 2011, Susp. Green Springs, Village of, 390492 April 2, 1976, ......do Do. Sandusky and...

  3. Guidelines for Hosted Payload Integration

    DTIC Science & Technology

    2014-06-06

    Micopac markking@micropac.com Andrew King Boeing andrew.m.king@boeing.com Byron Knight NRO knightby@nro.mil Hans Koenigsmann SpaceX hans.koenigsmann...jdsu.com Marvin VanderWeg SpaceX marvin.vanderwag@spacex.c om Gerrit VanOmmering SSL gerrit.vanommering@sslmda. com Michael Verzuh Ball mverzuh@ball.com

  4. From Normalcy to Neoplasia. The Role of Epithelial-Stromal Interactions in Regulating Mammary Growth and Differentiation

    DTIC Science & Technology

    2000-08-01

    through the cell Fantl V, Stamp G, Andrews A, Rosewell I, Dickson C. 1995. Mice cycle are able to die. The local concentrations of inhibi- lacking...Cyclin DI provides a link between development and oncogenesis in the retina and breast. Cell 82:621-630. 29. V. Fantl, G. Stamp, A. Andrews, I. Rosewell

  5. Argument Reconceived?

    ERIC Educational Resources Information Center

    Coffin, Caroline; O'Halloran, Kieran A.

    2009-01-01

    Just over 10 years ago, "Educational Review" published an article "Reconceiving argument" by Richard Andrews. In the article, Andrews traced some of the changes in the conception of argument that had taken place within educational contexts (primarily within the UK) over the previous few years. An important aim of the authors'…

  6. Counterfeit Parts Prevention Strategy Guide Product Overview

    DTIC Science & Technology

    2014-05-08

    pwr.utc.com Mark King Micopac markking@micropac.com Andrew King Boeing andrew.m.king@boeing.com Byron Knight NRO knightby@nro.mil Hans Koenigsmann SpaceX ...Marvin VanderWeg SpaceX marvin.vanderwag@spacex.com Gerrit VanOmmering SSL gerrit.vanommering@sslmda.com Michael Verzuh Ball mverzuh@ball.com John Vilja

  7. Root Cause Investigation (RCI) Best Practices Guide Product Overview

    DTIC Science & Technology

    2014-05-08

    micropac.com Andrew King Boeing andrew.m.king@boeing.com Byron Knight NRO knightby@nro.mil Hans Koenigsmann SpaceX hans.koenigsmann@spacex.com James Koory...ghislain.turgeon@sslmda.com Deborah Valley MIT deborah.valley@ll.mit.edu Fred Van Milligen JDSU fvanmilligen@jdsu.com Marvin VanderWeg SpaceX marvin.vanderwag

  8. Baclofen blocks the acquisition and expression of mitragynine-induced conditioned place preference in rats.

    PubMed

    Yusoff, Nurul H M; Mansor, Sharif M; Müller, Christian P; Hassan, Zurina

    2018-06-01

    Mitragynine is the major alkaloid found in the leaves of M. speciosa Korth (Rubiaceae), a plant that is native to Southeast Asia. This compound has been used, either traditionally or recreationally, due to its psychostimulant and opioid-like effects. Recently, mitragynine has been shown to exert conditioned place preference (CPP), indicating the rewarding and motivational properties of M. speciosa. Here, the involvement of GABA B receptors in mediating mitragynine reward is studied using a CPP paradigm in rats. First, we examined the effects of GABA B receptor agonist baclofen (1.25, 2.5 and 5 mg/kg) on the acquisition of mitragynine (10 mg/kg)-induced CPP. Second, the involvement of GABA B receptors in the expression of mitragynine-induced CPP was tested. We found that the acquisition of mitragynine-induced CPP could be blocked by higher doses (2.5 and 5 mg/kg) of baclofen. Baclofen at a high dose inhibited locomotor activity and caused a CPP. Furthermore, we found that baclofen (2.5 and 5 mg/kg) also blocked the expression of mitragynine-induced CPP. These findings suggest that both, the acquisition and expression of mitragynine's reinforcing properties is controlled by the GABA B receptor. Copyright © 2018 Elsevier B.V. All rights reserved.

  9. The Evolution of an Adolescent Literacy Program: A Foundation's Journey

    ERIC Educational Resources Information Center

    Henriquez, Andres

    2005-01-01

    The Carnegie Corporation of New York is associated with the very foundations of literacy going back to the philanthropy of Andrew Carnegie himself and of the Corporation in its early years. Andrew Carnegie's legacy includes over 2,500 free public libraries that he saw as a link "bridging ignorance and education." In fact, Carnegie, the…

  10. BMP7 Induces Dormancy of Prostatic Tumor Stem Cell in Bone

    DTIC Science & Technology

    2013-07-01

    Watabe, Shigeru Hirota, Sudha K. Pai, Wen Liu, Koji Fukuda, Christopher Chambers, Andrew Wilber and Kounosuke Watabe “Bone Figure 7. Expression of BMP7...Hiroshi Okuda,1 Fei Xing,1 Puspa R. Pandey,1 Misako Watabe,1 Shigeru Hirota,2 Sudha K. Pai,1 Wen Liu,1 Koji Fukuda,1 Christopher Chambers,1 Andrew

  11. The Patterns and Dynamics of Revolution: Insights into Iraq

    DTIC Science & Technology

    2005-03-18

    197. 80 Rabasa, 56. 26 81 Ibid., 53. 82 Roger Cohen. 83 Crane and Terrill, 33. 84 Andrew Krepinevich, "Iraq and Vietnam: Deja vu all over Again?" 8...in Iraq." Christian Science Monitor, 20 September 2004, 1. Krepinevich, Andrew. "Iraq and Vietnam: Deja vu all over Again?" Center for Strategic and

  12. C and N Content in Density Fractions of Whole Soil and Soil Size Fraction Under Cacao Agroforestry Systems and Natural Forest in Bahia, Brazil

    NASA Astrophysics Data System (ADS)

    Rita, Joice Cleide O.; Gama-Rodrigues, Emanuela Forestieri; Gama-Rodrigues, Antonio Carlos; Polidoro, Jose Carlos; Machado, Regina Cele R.; Baligar, Virupax C.

    2011-07-01

    Agroforestry systems (AFSs) have an important role in capturing above and below ground soil carbon and play a dominant role in mitigation of atmospheric CO2. Attempts has been made here to identify soil organic matter fractions in the cacao-AFSs that have different susceptibility to microbial decomposition and further represent the basis of understanding soil C dynamics. The objective of this study was to characterize the organic matter density fractions and soil size fractions in soils of two types of cacao agroforestry systems and to compare with an adjacent natural forest in Bahia, Brazil. The land-use systems studied were: (1) a 30-year-old stand of natural forest with cacao (cacao cabruca), (2) a 30-year-old stand of cacao with Erythrina glauca as shade trees (cacao + erythrina), and (3) an adjacent natural forest without cacao. Soil samples were collected from 0-10 cm depth layer in reddish-yellow Oxisols. Soil samples was separated by wet sieving into five fraction-size classes (>2000 μm, 1000-2000 μm, 250-1000 μm, 53-250 μm, and <53 μm). C and N accumulated in to the light (free- and intra-aggregate density fractions) and heavy fractions of whole soil and soil size fraction were determined. Soil size fraction obtained in cacao AFS soils consisted mainly (65 %) of mega-aggregates (>2000 μm) mixed with macroaggregates (32-34%), and microaggregates (1-1.3%). Soil organic carbon (SOC) and total N content increased with increasing soil size fraction in all land-use systems. Organic C-to-total N ratio was higher in the macroaggregate than in the microaggregate. In general, in natural forest and cacao cabruca the contribution of C and N in the light and heavy fractions was similar. However, in cacao + erythrina the heavy fraction was the most common and contributed 67% of C and 63% of N. Finding of this study shows that the majority of C and N in all three systems studied are found in macroaggregates, particularly in the 250-1000 μm size aggregate class

  13. C and N content in density fractions of whole soil and soil size fraction under cacao agroforestry systems and natural forest in Bahia, Brazil.

    PubMed

    Rita, Joice Cleide O; Gama-Rodrigues, Emanuela Forestieri; Gama-Rodrigues, Antonio Carlos; Polidoro, Jose Carlos; Machado, Regina Cele R; Baligar, Virupax C

    2011-07-01

    Agroforestry systems (AFSs) have an important role in capturing above and below ground soil carbon and play a dominant role in mitigation of atmospheric CO(2). Attempts has been made here to identify soil organic matter fractions in the cacao-AFSs that have different susceptibility to microbial decomposition and further represent the basis of understanding soil C dynamics. The objective of this study was to characterize the organic matter density fractions and soil size fractions in soils of two types of cacao agroforestry systems and to compare with an adjacent natural forest in Bahia, Brazil. The land-use systems studied were: (1) a 30-year-old stand of natural forest with cacao (cacao cabruca), (2) a 30-year-old stand of cacao with Erythrina glauca as shade trees (cacao + erythrina), and (3) an adjacent natural forest without cacao. Soil samples were collected from 0-10 cm depth layer in reddish-yellow Oxisols. Soil samples was separated by wet sieving into five fraction-size classes (>2000 μm, 1000-2000 μm, 250-1000 μm, 53-250 μm, and <53 μm). C and N accumulated in to the light (free- and intra-aggregate density fractions) and heavy fractions of whole soil and soil size fraction were determined. Soil size fraction obtained in cacao AFS soils consisted mainly (65 %) of mega-aggregates (>2000 μm) mixed with macroaggregates (32-34%), and microaggregates (1-1.3%). Soil organic carbon (SOC) and total N content increased with increasing soil size fraction in all land-use systems. Organic C-to-total N ratio was higher in the macroaggregate than in the microaggregate. In general, in natural forest and cacao cabruca the contribution of C and N in the light and heavy fractions was similar. However, in cacao + erythrina the heavy fraction was the most common and contributed 67% of C and 63% of N. Finding of this study shows that the majority of C and N in all three systems studied are found in macroaggregates, particularly in the 250-1000 μm size

  14. Populations of Erythrina velutina Willd. at risk of extinction.

    PubMed

    Melo, M F V; Gonçalves, L O; Rabbani, A R C; Álvares-Carvalho, S V; Pinheiro, J B; Zucchi, M I; Silva-Mann, R

    2015-08-28

    The goal of this study was to characterize the structure of two natural populations of the coral tree using RAPD and ISSR markers. The study evaluated all individuals in two different areas in the northeastern region of Brazil: the first was in the riparian area, 10 km x 100 m along the edge of the lower São Francisco River, and the second was in the municipality of Pinhão, in a semiarid region between the municipalities of Neópolis and Santana do São Francisco. We used all the coral trees present in those two areas (37 individuals). The results of the RAPD and ISSR markers were highly congruent, supporting the reliability of the techniques used. Similarity was estimated using the Jaccard arithmetic complement index. A dendrogram was constructed using the unweighted pair group method with arithmetic mean cluster algorithm, and the robustness of the data was bootstrapped with 5000 replicates. A principal coordinate analysis was performed on the basis of Jaccard coefficients. The total genetic variation observed was 21%, corresponding to the variation between the populations, and 79% of the variation was observed within the populations.

  15. CPHC/WFO Honolulu Gallery

    Science.gov Websites

    another search. Multiple locations were found. Please select one of the following: Close Location Help Top view Zoom in shot of snow on the Big Island Summits 11/5/2007 (photo by Andrew Beavers (NWS)) Zoom in shot of snow on the Big Island Summits 11/5/2007 (photo by Andrew Beavers (NWS)) Click for larger view

  16. High-Speek Polymer Fiber Electrooptic Modulators and Devices

    DTIC Science & Technology

    1999-12-10

    R. F. Shi, A. F. Garito, and C. H. Grossman, Opt. Lett. 19, 786 (1994). [5] J. H. Andrews, J. D. V. Khaydarov , and K. D. Singer, Opt. Lett. 19, 984...1994). [6] J. H. Andrews, J. D. V. Khaydarov , and K. D. Singer, Opt. Lett. 19, 1909 (1994) [7] C. Poga, T. M. Brown, M. G. Kuzyk, and C. W. Dirk, J

  17. Conversion of Radio-Frequency Pulses to Continuous-Wave Sinusoids by Fast Switching and Narrowband Filtering

    DTIC Science & Technology

    2016-09-01

    Switching and Narrowband Filtering by Gregory J Mazzaro, Andrew J Sherbondy, Kenneth I Ranney, and Kelly D Sherbondy...Switching and Narrowband Filtering by Gregory J Mazzaro, Andrew J Sherbondy, Kenneth I Ranney, and Kelly D Sherbondy Sensors and Electron Devices...08/2016 4. TITLE AND SUBTITLE Conversion of Radio-Frequency Pulses to Continuous-Wave Sinusoids by Fast Switching and Narrowband Filtering 5a

  18. Characterization of Bacterial Communities and Asaia Infection with Field-Collected and Laboratory-Reared Aedes albopictus

    DTIC Science & Technology

    2016-08-18

    Characterization of bacterial communities and Asaia infection within field-collected and 1 laboratory-reared Aedes albopictus 2 3 4 Elizabeth S...Running Head: Bacterial communities within Ae. albopictus 10 11 #Address correspondence to Elizabeth S. Andrews, elizabeth.s.andrews11.ctr@mail.mil 12...189 DISTRIBUTION STATEMENT A: Approved for public release; distribution is unlimited. UNCLASSIFIED Abstract 19 The bacterial communities within

  19. Influence of Preadjusted Bracket Shape and Positioning Reference on Angulation of Upper Central Incisor.

    PubMed

    Topolski, Francielle; de O Accorsi, Mauricio A; Trevisi, Hugo J; Cuoghi, Osmar A; Moresca, Ricardo

    2016-10-01

    To verify the influence of different bracket shapes and placement references according to Andrews and MBT systems on the expression of angulation in upper central incisors (UCI). Bracket positioning and mesiodistal dental movement simulations were performed and the angulations produced in the dental crown were evaluated, based on computed tomography scan images of 30 UCI and AutoCAD software analysis. Rectangular (Andrews) and rhomboid (MBT) brackets were placed according to the references recommended by Andrews and MBT systems - long axis of the clinical crown (LACC) and incisal edge (IE) respectively. Data showed that the use of LACC as reference for bracket positioning produced 5° and 4° UCI angulations in Andrews and MBT brackets respectively. The use of IE produced a 1.2° mean angulation in UCI for both brackets. When the LACC was used as reference for bracket positioning, the UCI crown angulation corresponded to the angulation built into the brackets, regardless of shape, while the use of IE resulted in natural crown angulation, regardless of bracket shape. This research contributes to guide the orthodontist in relation to the different treatment techniques based on the use of preadjusted brackets.

  20. The Andrews’ Principles of Risk, Need, and Responsivity as Applied in Drug Abuse Treatment Programs: Meta-Analysis of Crime and Drug Use Outcomes

    PubMed Central

    Prendergast, Michael L.; Pearson, Frank S.; Podus, Deborah; Hamilton, Zachary K.; Greenwell, Lisa

    2013-01-01

    Objectives The purpose of the present meta-analysis was to answer the question: Can the Andrews principles of risk, needs, and responsivity, originally developed for programs that treat offenders, be extended to programs that treat drug abusers? Methods Drawing from a dataset that included 243 independent comparisons, we conducted random-effects meta-regression and ANOVA-analog meta-analyses to test the Andrews principles by averaging crime and drug use outcomes over a diverse set of programs for drug abuse problems. Results For crime outcomes, in the meta-regressions the point estimates for each of the principles were substantial, consistent with previous studies of the Andrews principles. There was also a substantial point estimate for programs exhibiting a greater number of the principles. However, almost all of the 95% confidence intervals included the zero point. For drug use outcomes, in the meta-regressions the point estimates for each of the principles was approximately zero; however, the point estimate for programs exhibiting a greater number of the principles was somewhat positive. All of the estimates for the drug use principles had confidence intervals that included the zero point. Conclusions This study supports previous findings from primary research studies targeting the Andrews principles that those principles are effective in reducing crime outcomes, here in meta-analytic research focused on drug treatment programs. By contrast, programs that follow the principles appear to have very little effect on drug use outcomes. Primary research studies that experimentally test the Andrews principles in drug treatment programs are recommended. PMID:24058325

  1. Alternatives to Address Role Clarification at the U.S. Army Community Hospital, Fort Polk

    DTIC Science & Technology

    1981-06-01

    Szilagyi , Andrew D., and Wallace , Marc J., Organizational Behavior and Performance (Santa Monica: Goodyear Publishing Company, 1977): Page 214. 14...Institute For Social Research, The University of Michigan, Ann Arbor, Michigan, 1972. Ivancevich, John M., Szilagyi , Andrew D. and Wallace , Marc J...opposed to professional and technical groups. 1 1 Another study by Szilagyi and Sims postulated the existence of a role ambiguity continuum which revealed

  2. Institute for the Study of Human Capabilities

    DTIC Science & Technology

    1992-08-01

    Illinois, and C. S. Watson served as conference chairpersons. Other speakers included Andrew Dillon, Colin Drury , Earl Hunt, Barry Kantowitz, Raja...Parasuraman (Catholic University of America, Washington, D.C.), and Colin Drury (SUNY, Buffalo). Two Speakers from the U.K. were Andrew Dillon, the...research organizations in the U.K. In June, 1992, Ada Simmons, who served as a very capable administrative assistant/office manager/grants accountant

  3. Acquisition and Retention of Team Coordination in Command-and-Control

    DTIC Science & Technology

    2007-07-01

    Pedersen Jennifer Winner Jasmine Duran Amanda Taylor Polemnia G. Amazeen Dee H. Andrews Leah Rowe Cognitive Engineering Research Institute 5810 S...Winner, Jasmine Duran, Amanda Taylor, Polemnia G. Amazeen, Dee H. Andrews, and Leah Rowe 5f. WORK UNIT NUMBER 1123AM02 7. PERFORMING...Psychology, ASU Polytechnic Consultant Nia Amazeen, Ph.D. Associate Professor, Psychology, ASU Graduate Students Jasmine Duran, CERI & ASU Jamie C

  4. Cake: Enabling High-level SLOs on Shared Storage Systems

    DTIC Science & Technology

    2012-11-07

    Cake: Enabling High-level SLOs on Shared Storage Systems Andrew Wang Shivaram Venkataraman Sara Alspaugh Randy H. Katz Ion Stoica Electrical...Date) * * * * * * * Professor R. Katz Second Reader (Date) Cake: Enabling High-level SLOs on Shared Storage Systems Andrew Wang, Shivaram Venkataraman ...Report MIT-LCS-TR-667, MIT, Laboratory for Computer Science, 1995. [39] A. Wang, S. Venkataraman , S. Alspaugh, I. Stoica, and R. Katz. Sweet storage SLOs

  5. A Moving Discontinuous Galerkin Finite Element Method for Flows with Interfaces

    DTIC Science & Technology

    2017-12-07

    Naval Research Laboratory Washington, DC 20375-5320 NRL/MR/6040--17-9765 A Moving Discontinuous Galerkin Finite Element Method for Flows with...guidance to revise the method to ensure such properties. Acknowledgements This work was sponsored by the Office of Naval Research through the Naval...18. NUMBER OF PAGES 17. LIMITATION OF ABSTRACT A Moving Discontinuous Galerkin Finite Element Method for Flows with Interfaces Andrew Corrigan, Andrew

  6. Photo-Healable Metallosupramolecular Polymers

    DTIC Science & Technology

    2014-01-09

    doi: 10.1038/nmat2891 Mark Burnworth, Liming Tang , Justin R. Kumpfer, Andrew J. Duncan, Frederick L. Beyer, Gina L. Fiore, Stuart J. Rowan...Mark Burnworth, Liming Tang , Stuart J. Rowan, Christoph Weder. Reinforcement of Self- Healing Polymer Films with Cellulose Nanowhiskers, ACS PMSE...Macromolecules (08 2011) Mark Burnworth, Liming Tang , Justin R. Kumpfer, Andrew J. Duncan, Frederick L. Beyer, Stuart J. Rowan, Christoph Weder

  7. General Merrill A. McPeak: An Effective Change Agent?

    DTIC Science & Technology

    1997-04-01

    McPeak, 115-121. 18 Interview with General McPeak, 21 March 1997. 24 Chapter 7 Managing Change Wallace and Szilagyi in Managing Behavior in...Andrew D. Szilagyi , Jr., Managing Behavior in Organizations, (Glenview, Illinois, Scott, Foesman and Company, 1982), 387. 2 Jaques and Clement, 274. 3...Airman. Nov ‘93. Wallace, Marc J. and Szilagyi , Andrew D. Managing Behavior in Organizations. Glenview, IL., Scott, Foesman and Company, 1982

  8. Avoiding Armageddon: The US Military’s Response to Trans-Regional Nuclear Proliferation in a Post-Soviet World

    DTIC Science & Technology

    2016-05-26

    Post -Soviet World A Monograph by MAJ Andrew S. Glenn US Army School of Advanced Military Studies United States Army Command and General...2016 4. TITLE AND SUBTITLE Avoiding Armageddon: The US Military1s Response to Trans-Regional Nuclear Proliferation in a Post -Soviet World Sa...MAJ Andrew S. Glenn Monograph Title: Avoiding Armageddon: The US Military’s Response to Trans- Regional Nuclear Proliferation in a Post -Soviet

  9. Effects of Benthic Barriers on Macroinvertebrate Communities

    DTIC Science & Technology

    1993-10-01

    Aquatic Plant Control Research Program Effects of Benthic Barriers on Macroinvertebrate Communities by Barry S. Payne, Andrew C. Miller Environmental...Plant Control Technical Report A-93-5Resear h Program Oct ber 1993 Effects of Benthic Barriers on Macroinvertebrate Communities by Barry S. Payne...Effects of benthic barriers on macroinvertebrate communities / by Barry S. Payne, Andrew C. Miller, [and] Thomas Ussery ; prepared for U.S. Army Corps of

  10. Modern Social Media and Social Revolutions

    DTIC Science & Technology

    2011-12-16

    Ravi Kumar, Jasmine Noval, and Andrew Tomkins found similar results in their study of “Flickr” and “Yahoo! 360” (Kumar, Novak, and Tomkins 2006...the event through passive engagement, in essence , creating a feedback loop that gets stronger with the passage of time. Given the instantaneity at...to the digital age. New York: The Continuum Publishing Company. Kumar, Ravi, Jasmine Novak, and Andrew Tomkins. 2006. Structure and evolution of

  11. Non-Kinetic Shaping Operations: The Soviet Information Campaign Supporting the Invasion of Afghanistan

    DTIC Science & Technology

    2009-01-01

    jihad that pitted the triballashkar (defense forces) against therepresentatives of the national government. The Marxist-Leninist based People’s Democratic...December 13, 2008. 10 Ibid.,7. 11 Ibid., 14. 12 Ibid., 15. 13Ibid.,16. 14 Christopher Andrew and Vasili Mitrokhin, The World Was Going our Way: The...Occupation. Washington D.C.: National Defense University, 1986. Andrew, Christopher, and Vasili Mitrokhin. The World Was Going our Way: The KGB and

  12. ARC-2009-ACD09-0084

    NASA Image and Video Library

    2009-05-14

    Dan Andrews, Project Manager LCROSS and Craig Tooley, Project Manager LRO (Lunar Reconnaissance Orbiter) in front of Spacecraft at the Astrotech facility titusville, FL during LRO/LCROSS media photo op event. The LCROSS mission's objective is to confirm the presence or absence of water ice in a permanently shadowed crater at the moon's South Pole. (Photo by Jonis Dino AMES PAO, premission for use granted by Dan Andrews, image owner)

  13. Evaluation of Quantitative Anti-F1 IgG and Anti-V IgG ELISAs for use as an in Vitro-Based Potency Assay of Plague Vaccine in Mice

    DTIC Science & Technology

    2008-04-01

    Andrews GP, Welkos SL, Friedlander AM, et al. Protection of mice from fatal bubonic and pneu- monic plague by passive immunization with monoclonal...SL, Andrews GP, Adamovicz J, et al. Protection against experimental bubonic and pneumonic plague by a recombinant capsular F1-V antigen fusion...fusion protein as vaccine antigen against bubonic and pneumonic plague . Biotechnol Prog 2005; 21:1490e510.[21] Simpson WJ, Thomas RE, Schwan TG

  14. Design of a Multi-Week Sound and Motion Recording and Telemetry (SMRT) Tag for Behavioral Studies on Whales

    DTIC Science & Technology

    2015-09-30

    phone: +44 1334 462624 fax: +44 1334 463443 e-mail: markjohnson@st-andrews.ac.uk Todd Lindstrom Wildlife Computers 8345 154th Avenue NE...in situ processing algorithms for sound and motion data. In a parallel project Dr. Andrews at the Alaska SeaLife Center teamed with Wildlife ...from Wildlife Computers to produce a highly integrated Sound and Motion Recording and Telemetry (SMRT) tag. The complete tag development is expected

  15. Microstructure and Properties of WC Spheres

    DTIC Science & Technology

    2008-11-01

    Microstructure and Properties of WC Spheres by Jeffrey J. Swab, Justin Pritchett, Andrew A . Wereszczak, and Osama M. Jadaan ARL-TR-4634...Pritchett Oak Ridge Institute for Science and Education Andrew A . Wereszczak Oak Ridge National Laboratory Osama M. Jadaan University of ...shall be subject to any penalty for failing to comply with a collection of information if it does not display a currently valid OMB control number

  16. Intramembranous ossification of scleral ossicles in Chelydra serpentina.

    PubMed

    Franz-Odendaal, Tamara A

    2006-01-01

    Scleral ossicles are present in many reptiles, including turtles and birds. In both groups the sclerotic ring situated in the eye is composed of a number of imbricating scleral ossicles or plates. Despite this gross morphological similarity, Andrews (1996. An endochondral rather than a dermal origin for scleral ossicles in Cryptodiran turtles. J. Herpetol. 30, 257-260) reported that the scleral ossicles of turtles develop endochondrally unlike those in birds, which develop intramembranously after a complex epithelial-mesenchymal inductive event. This study re-explores one of the species examined by Andrews in order to determine the mode of ossification of scleral ossicles in turtles. A growth series of Chelydra serpentina embryos, including the stages examined by Andrews, were examined by staining separately for cartilage and bone. Results clearly contradict Andrews (1996) and show that the scleral ossicles of Chelydra serpentina develop similarly to those in birds. That is, they develop intramembranously without a cartilage precursor and are likely induced by transient scleral papillae. The sequence of scleral papillae development is broadly similar, but the papillae themselves are not as distinct as those seen in chicken embryos. This study has important consequences for understanding the homology of scleral ossicles among tetrapods.

  17. Acquisition and Retention of Team Coordination in Command-and-Control

    DTIC Science & Technology

    2007-05-15

    Pedersen, Jennifer Winner, Jasmine Duran, Amanda Taylor, Polemnia G. Amazeen, So. TASK NUMBER Dee Andrews, Leah Rowe 5f. WORK UNIT NUMBER 7. PERFORMING...and- Control Nancy J. Cooke, Jamie C. Gorman, Harry K. Pedersen, Jennifer Winner, Jasmine Duran, Amanda Taylor, Nia Amazeen, Dee Andrews, and Leah Rowe...Psychology, ASU Graduate Students Jasmine Duran, CERI & ASU Jamie C. Gorman, Ph.D., CERI & NMSU * (Ph.D. obtained Dec. 2006) Harry K. Pedersen, CERI

  18. My Lovely C-Section

    PubMed Central

    Taylor, Katherine

    2010-01-01

    Katherine and Andrew Taylor chose to have a planned home birth. With the support of her husband, Andrew, and her midwife and doula, Katherine labored at home for 48 hours before transferring to the hospital. Baby Luke was born by cesarean about 20 hours later. Confident and supported, the Taylors were able to make informed decisions and have a positive birth experience, although it was not what they had planned. PMID:21358828

  19. Smart Core-Shell Nanowire Architectures for Multifunctional Nanoscale Devices

    DTIC Science & Technology

    2014-02-16

    Andrew R. Akbashev, Peter K. Davies, Jonathan E. Spanier, Andrew M. Rappe. Perovskite oxides for visible- light -absorbing ferroelectric and...without loss of polar character. Shown for a single phase solid solution ferroelectric oxide perovskite (K,Ba),(Ni,Nb)O_(3-delta), this material...exhibits a compositionally tunable and direct band gap in the range of 1.1 – 3.8 eV, with potential for novel nonlinear light -matter applications in addition

  20. Extending the Thin Blue Line: Constabulary Police Development in Phase Zero Operations

    DTIC Science & Technology

    2015-05-16

    131Ibid. 132James Dobbins, Seth G. Jones, Keith Crane, Andrew Rathmell, and Brett Steele , The UN’s role in nation-building: From the... Malaysia , and Portugal.136 Both operations in East Timor were military-led and emphasized security. When Australian intervened in the Solomon Islands...1993. Dobbins, James, Seth G. Jones, Keith Crane, Andrew Rathmell, and Brett Steele . The UN’s role in nation-building: From the Congo to Iraq Vol

  1. Acquisition of Oceanographic Measurements from Baleen Whales and Acquisition of Oceanographic Measurements from Baleen Whales: Field Deployments of Tags Developed Under Grant ONR (N00014-13-1-0854)

    DTIC Science & Technology

    2015-09-30

    Jonas Teilmann Department of Bioscience Aarhus University Fredriksborgvej 399 DK-4000 Roskilde Denmark phone: +45 21424291 fax: +45 87 16 87 51...Mammal Research Unit (SMRU, www.smru.st-andrews.ac.uk), University of St. Andrews, Scotland. WORK COMPLETED The project developed a prototype CTD...temperature and depth components from that work along with the tag controller/transmitter etc, are all still valid. • The risk for building a new tag fall

  2. There Shall We Be Also: Tribal Fractures and Auxiliaries in the Indian Wars of the Northern Great Plains

    DTIC Science & Technology

    2008-11-20

    Director ~ Thomas A. BrUS ~h.D. Monograph Reader MiCh~~--- Director, School of Advanced Military Studies ~~~M ___ ’" Director, Robert F. Bau , Ph.D...Indians, Infants, and Infantry: Andrew and Elizabeth Burt on the Frontier (Lincoln, NE: University of Nebraska Press, 1988), 130-132; Dunlay, Wolves for...Indians, Infants, and Infantry: Andrew and Elizabeth Burt on the Frontier. Lincoln, NE: University of Nebraska Press, 1988. Morgan, Patrick. "How

  3. A cockspur for the DSS cells: Erythrina crista-galli sensitizers

    NASA Astrophysics Data System (ADS)

    Enciso, Paula; Decoppet, Jean-David; Grätzel, Michael; Wörner, Michael; Cabrerizo, Franco M.; Cerdá, María Fernanda

    2017-04-01

    Dye sensitized solar cells were assembled employing a mixture of anthocyanins extracted from red ceibo's flowers. At the literature different extraction procedures are reported to extract anthocyanins from natural products and sensitize the cells. In order to compare them, different methods were followed to set the cells under the same conditions. Assembled cells showed very interesting conversion efficiency values, reaching a 0.73% value for extracts purified using C18 column, in open cells under illumination using a solar light simulator, 1 sun, 1.5 AM. Data reported herein prove that anthocyanins obtained from ceibo's flower, after simple further purification, might represent an excellent, cheap and clean alternative for the development of DSS cells.

  4. The US Army and the Interagency Process: Historical Perspectives. The Proceedings of the Combat Studies Institute 2008 Military History Symposium (6th) Held at Fort Leavenworth, Kansas on 16-18 September 2008

    DTIC Science & Technology

    2008-09-01

    and that no invasion was con­ templated.36 After Vessey departed for Chicago, the acting chairman, Admiral James Watkins , the new Chief of Naval...European Advisory Commission; Austria; Germany. Dobbins, James, John G. McGinn, Keith Crane, Seth G. Jones, Rollie Lal, Andrew Rathmell, Rachel M...86. James Dobbins, John G. McGinn, Keith Crane, Seth G. Jones, Rollie Lal, Andrew Rath­ mell, Rachel M. Swanger, Anga R. Timilsina, “America’s Role in

  5. Evolution of Zinc Oxide Nanostructures from Non-Equilibrium Deposition Conditions

    DTIC Science & Technology

    2016-07-11

    pressure and temperature in the chamber by a rough estimation using PV = nRT. The deposition area is the internal surface of the tubular chamber, D...J. Wang, L. Zhang, T.L. Andrew, M.S. Arnold, X.D. Wang “Development of Lead Iodide Perovskite Solar Cells Using Three-Dimensional Titanium Dioxide...Andrew, M.S. Arnold, X.D. Wang "Development of Lead Iodide Perovskite Solar Cells Using Three-Dimensional Titanium Dioxide Nanowire Architectures" ACS

  6. Airpower Against an Army: Challenge and Response in CENTAF’S Duel with the Republican Guard

    DTIC Science & Technology

    1995-06-01

    Challenge and Response in CENTAF’S Duel with the Republican Guard Contract or Grant Number Program Element Number Authors Andrews, William F...unlimited Number of Pages 140 AIRPOWER AGAINST AN ARMY CHALLENGE AND RESPONSE IN CENTAF’S DUEL WITH THE REPUBLICAN GUARD BY WILLIAM F. ANDREWS A THESIS...of the battle had been shaped by CENTAF’s month long duel with the Iraqi Army. As the first troops crossed the Iraqi border the Republican Guard heavy

  7. Return to Clark Air Force Base: Establishing Permanent Military Bases in the Philippines as part of the United States Grand Strategy in the South China Sea

    DTIC Science & Technology

    2016-02-16

    Unknotting tangled Lines in the South China Sea Dispute” in Territorial Disputes in the South China Sea ed. Billo, Andrew and Jung 1-12 Hayton...in Territorial Disputes in the South China Sea ed. Billo, Andrew and Jung 99-127 Johnston, Alastair, “How New and Assertive Is China’s New...2015) Sutter, Robert, “China’s Rise: Implications for U.S. Leadership in Asia,” East-West Center, Washington, Policy Studies 21. (2006) Thayer, Carl

  8. Novel Therapeutic Targets for Chronic Migraine

    DTIC Science & Technology

    2014-11-01

    A D Award Number: W81XWH-11-1-0646 TITLE: Novel Therapeutic Targets for Chronic Migraine PRINCIPAL INVESTIGATORS: Andrew Charles CONTRACTING...for Chronic Migraine 5a. CONTRACT NUMBER 5b. GRANT NUMBER W81XWH-11-1-0646 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Andrew Charles, M.D. and Peter...Chronic migraine is a disabling disorder that affects millions of individuals worldwide, and may result from traumatic brain injury. The purpose of this

  9. Modern Perspectives in Applied Mathematics: Theory and Numerics of PDEs

    DTIC Science & Technology

    2015-04-13

    Stokes-Fokker- Planck systems 09:45 – 10:25 Helena Lopes (Universidade Federal do Rio de Janeiro ) Boundary correctors and energy estimates for...Duke%University x Helena Lopes Universidade%Federal%do% Rio % de % Janeiro x x Andrew Majda New%York%University x Siddhartha Mishra ETH%Zurich x Stanley...09:00 – 09:40 Chair: Doron Levy (University of Maryland) Pierre-Louis Lions (Collège de France) 09:45 – 10:25 Andrew Majda (New York University

  10. SEI Report on Graduate Software Engineering Education for 1991

    DTIC Science & Technology

    1991-04-01

    12, 12 (Dec. 1979), 85-94. Andrews83 Andrews, Gregory R . and Schneider, Fred B. “Concepts and Notations for Concurrent Programming.” ACM Computing...Barringer87 Barringer , H. “Up and Down the Temporal Way.” Computer J. 30, 2 (Apr. 1987), 134-148. Bjørner78 The Vienna Development Method: The Meta-Language...Lecture Notes in Computer Science. Bruns86 Bruns, Glenn R . Technology Assessment: PAISLEY. Tech. Rep. MCC TR STP-296-86, MCC, Austin, Texas, Sept

  11. ACES: An Enabling Technology for Next Generation Space Transportation

    NASA Astrophysics Data System (ADS)

    Crocker, Andrew M.; Wuerl, Adam M.; Andrews, Jason E.; Andrews, Dana G.

    2004-02-01

    Andrews Space has developed the ``Alchemist'' Air Collection and Enrichment System (ACES), a dual-mode propulsion system that enables safe, economical launch systems that take off and land horizontally. Alchemist generates liquid oxygen through separation of atmospheric air using the refrigeration capacity of liquid hydrogen. The key benefit of Alchemist is that it minimizes vehicle takeoff weight. All internal and NASA-funded activities have shown that ACES, previously proposed for hypersonic combined cycle RLVs, is a higher payoff, lower-risk technology if LOX generation is performed while the vehicle cruises subsonically. Andrews Space has developed the Alchemist concept from a small system study to viable Next Generation launch system technology, conducting not only feasibility studies but also related hardware tests, and it has planned a detailed risk reduction program which employs an experienced, proven contractor team. Andrews also has participated in preliminary studies of an evolvable Next Generation vehicle architecture-enabled by Alchemist ACES-which could meet civil, military, and commercial space requirements within two decades.

  12. Co-creating health's lively, moving frontiers: brief observations on the facets and possibilities of non-representational theory.

    PubMed

    Andrews, Gavin J

    2014-11-01

    This paper follows up a recent debate on the potential of non-representational theory in health geography (see Andrews et al 2014; Kearns 2014; Hanlon 2014; Andrews 2014c) by outlining, more broadly, some of its key facets and investigative possibilities. The intention is to provide a helpful introduction, and entry point, to this particular way of understanding the world and of going about research that might help scholars reverberate the 'taking place' of health and health care. Copyright © 2014 Elsevier Ltd. All rights reserved.

  13. Eddies as Offshore Foraging Grounds for Melon-Headed Whales (Peponocephala electra)

    DTIC Science & Technology

    2011-01-01

    Andrews, R. D., R. L. Pitman and L. T. Ballance. 2008. Satellite tracking reveals distinct movement patterns for Type B and Type C killer whales in...Science. DOI: 10.1111/j.1748-7692.2011.00517.x NOTES 9 Baird, R. W., A. M. Gorgone, D. J. McSweeney, et al. 2008a. False killer whales (Pseu- dorca...G. S. Schorr, D. L. Webster, D. J. McSweeney, M. B. Hanson and R. D. Andrews. 2010. Movements of satellite-tagged false killer whales around the

  14. The Cypriot-Turkish Conflict and NATO-European Union Cooperation

    DTIC Science & Technology

    2017-06-01

    Putin Would Want the Cyprus Talks to Fail.” 176 Ibid. 177 Andrew Rettman, “Cyprus in spotlight on Russia money laundering ,” Euro Observer. February 2...2016, https://euobserver.com/foreign/132111. 48 ROC authorities allegedly failed “to apply money laundering legislation” in order to share in the...3D243495199311707%26_afrWindowM ode%3D0%26_adf.ctrl-state%3D197383t6u2_95. Rettman, Andrew. “Cyprus in spotlight on Russian money laundering .” Euro Observer

  15. The Future of the Andrew File System

    ScienceCinema

    Brashear, Drrick; Altman, Jeffry

    2018-05-25

    The talk will discuss the ten operational capabilities that have made AFS unique in the distributed file system space and how these capabilities are being expanded upon to meet the needs of the 21st century. Derrick Brashear and Jeffrey Altman will present a technical road map of new features and technical innovations that are under development by the OpenAFS community and Your File System, Inc. funded by a U.S. Department of Energy Small Business Innovative Research grant. The talk will end with a comparison of AFS to its modern days competitors.

  16. The Future of the Andrew File System

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brashear, Drrick; Altman, Jeffry

    2011-02-23

    The talk will discuss the ten operational capabilities that have made AFS unique in the distributed file system space and how these capabilities are being expanded upon to meet the needs of the 21st century. Derrick Brashear and Jeffrey Altman will present a technical road map of new features and technical innovations that are under development by the OpenAFS community and Your File System, Inc. funded by a U.S. Department of Energy Small Business Innovative Research grant. The talk will end with a comparison of AFS to its modern days competitors.

  17. KENNEDY SPACE CENTER, FLA. - Members of the STS-114 crew spend time becoming familiar with Shuttle and mission equipment. From left (in their blue suits) are Mission Specialists Soichi Noguchi, Stephen Robinson, Charles Camarda, Andrew Thomas and Wendy Lawrence; Commander Eileen Collins and Pilot James Kelly. Noguchi represents the Japanese Aerospace and Exploration Agency. They are looking at the thermal protection system insulation blankets being installed on an insert for Discovery’s nose cap. The STS-114 mission is Logistics Flight 1, which is scheduled to deliver supplies and equipment plus the external stowage platform to the International Space Station.

    NASA Image and Video Library

    2004-03-05

    KENNEDY SPACE CENTER, FLA. - Members of the STS-114 crew spend time becoming familiar with Shuttle and mission equipment. From left (in their blue suits) are Mission Specialists Soichi Noguchi, Stephen Robinson, Charles Camarda, Andrew Thomas and Wendy Lawrence; Commander Eileen Collins and Pilot James Kelly. Noguchi represents the Japanese Aerospace and Exploration Agency. They are looking at the thermal protection system insulation blankets being installed on an insert for Discovery’s nose cap. The STS-114 mission is Logistics Flight 1, which is scheduled to deliver supplies and equipment plus the external stowage platform to the International Space Station.

  18. KENNEDY SPACE CENTER, FLA. - The STS-114 crew stands underneath Discovery in the Orbiter Processing Facility. From left are Mission Specialist Stephen Robinson, Pilot James Kelly, Mission Specialist Charles Camarda, astronaut John Young, Commander Eileen Collins and Mission Specialists Andrew Thomas, Wendy Lawrence and Soichi Noguchi, who is with the Japanese Aerospace and Exploration Agency. Young is associate director, Technical, at Johnson Space Center. The crew is spending time becoming familiar with Shuttle and mission equipment. The mission is Logistics Flight 1, which is scheduled to deliver supplies and equipment plus the external stowage platform to the International Space Station.

    NASA Image and Video Library

    2004-03-05

    KENNEDY SPACE CENTER, FLA. - The STS-114 crew stands underneath Discovery in the Orbiter Processing Facility. From left are Mission Specialist Stephen Robinson, Pilot James Kelly, Mission Specialist Charles Camarda, astronaut John Young, Commander Eileen Collins and Mission Specialists Andrew Thomas, Wendy Lawrence and Soichi Noguchi, who is with the Japanese Aerospace and Exploration Agency. Young is associate director, Technical, at Johnson Space Center. The crew is spending time becoming familiar with Shuttle and mission equipment. The mission is Logistics Flight 1, which is scheduled to deliver supplies and equipment plus the external stowage platform to the International Space Station.

  19. KENNEDY SPACE CENTER, FLA. - - In the Orbiter Processing Facility, STS-114 Mission Specialists Andrew Thomas, Soichi Noguchi and Charles Camarda greet astronaut John Young (far right), who flew on the first flight of Space Shuttle Columbia with Robert Crippen. Behind Camarda is Pilot James Kelly. Young is associate director, Technical, at Johnson Space Center. Noguchi represents the Japanese Aerospace and Exploration Agency. The STS-114 crew is spending time becoming familiar with Shuttle and mission equipment. The mission is Logistics Flight 1, which is scheduled to deliver supplies and equipment plus the external stowage platform to the International Space Station.

    NASA Image and Video Library

    2004-03-05

    KENNEDY SPACE CENTER, FLA. - - In the Orbiter Processing Facility, STS-114 Mission Specialists Andrew Thomas, Soichi Noguchi and Charles Camarda greet astronaut John Young (far right), who flew on the first flight of Space Shuttle Columbia with Robert Crippen. Behind Camarda is Pilot James Kelly. Young is associate director, Technical, at Johnson Space Center. Noguchi represents the Japanese Aerospace and Exploration Agency. The STS-114 crew is spending time becoming familiar with Shuttle and mission equipment. The mission is Logistics Flight 1, which is scheduled to deliver supplies and equipment plus the external stowage platform to the International Space Station.

  20. Cumulative impacts of hurricanes on Florida mangrove ecosystems: Sediment deposition, storm surges and vegetation

    USGS Publications Warehouse

    Smith, T. J.; Anderson, G.H.; Balentine, K.; Tiling, G.; Ward, G.A.; Whelan, K.R.T.

    2009-01-01

    Hurricanes have shaped the structure of mangrove forests in the Everglades via wind damage, storm surges and sediment deposition. Immediate effects include changes to stem size-frequency distributions and to species relative abundance and density. Long-term impacts to mangroves are poorly understood at present. We examine impacts of Hurricane Wilma on mangroves and compare the results to findings from three previous storms (Labor Day, Donna, Andrew). Surges during Wilma destroyed ??? 1,250 ha of mangroves and set back recovery that started following Andrew. Data from permanent plots affected by Andrew and Wilma showed no differences among species or between hurricanes for stem mortality or basal area lost. Hurricane damage was related to hydro-geomorphic type of forest. Basin mangroves suffered significantly more damage than riverine or island mangroves. The hurricane by forest type interaction was highly significant. Andrew did slightly more damage to island mangroves. Wilma did significantly more damage to basin forests. This is most likely a result of the larger and more spatially extensive storm surge produced by Wilma. Forest damage was not related to amount of sediment deposited. Analyses of reports from Donna and the Labor Day storm indicate that some sites have recovered following catastrophic disturbance. Other sites have been permanently converted into a different ecosystem, namely intertidal mudflats. Our results indicate that mangroves are not in a steady state as has been recently claimed. ?? 2009 The Society of Wetland Scientists.

  1. Addictive personality factors.

    PubMed

    Kagan, D M

    1987-11-01

    This study was designed to compare mean scores obtained by alcoholics, compulsive gamblers, smokers, chronic joggers, and control subjects on six subfactors of the MacAndrew Alcoholism Scale. Results indicated that some MacAndrew factors may be more sensitive to additive pathology than others. Alcoholics emerged as the most pathological group, in terms of scores on the Cognitive Impairment, Social Maladjustment, and Risk Taking scales. Gamblers and smokers appeared to be distinctly different, more socially oriented addicts. Frequency of jogging was negatively related to measures of addiction but positively related to measures of compulsiveness.

  2. Direct Drive Fusion Energy Shock Ignition Designs for Sub-MJ Lasers

    DTIC Science & Technology

    2008-09-01

    FUSION ENERGY SHOCK IGNITION DESIGNS FOR SUB-MJ LASERS Andrew J. Schmitt, J. W. Bates, S. P. Obenschain, and S. T. Zalesak Plasma Physics Division, Naval Research Laboratory, Washington DC 20375 andrew.schmitt@nrl.navy.mil D. E. Fyfe LCP&FD, Naval Research Laboratory, Washington DC 20375 R. Betti Fusion Science Center and Laboratory for Laser Energetics, University of Rochester, Rochester NY New approaches in target design have increased the pos- sibility that useful fusion power can be generated with sub-MJ lasers. We have performed many 1D and 2D

  3. Photocatalytic reduction of organic pollutant under visible light by green route synthesized gold nanoparticles.

    PubMed

    Choudhary, Bharat C; Paul, Debajyoti; Gupta, Tarun; Tetgure, Sandesh R; Garole, Vaman J; Borse, Amulrao U; Garole, Dipak J

    2017-05-01

    We report a rapid method of green chemistry approach for synthesis of gold nanoparticles (AuNPs) using Lagerstroemia speciosa leaf extract (LSE). L. speciosa plant extract is known for its effective treatment of diabetes and kidney related problems. The green synthesis of AuNPs was complete within 30min at 25°C. The same could also be achieved within 2min at a higher reaction temperature (80°C). Both UV-visible spectroscopy and transmission electron microscopy results suggest that the morphology and size distribution of AuNPs are dependent on the pH of gold solution, gold concentration, volume of LSE, and reaction time and temperature. Comparison between Fourier transform infrared spectroscopy (FT-IR) spectra of LSE and the synthesized AuNPs indicate an active role of polyphenolic functional groups (from gallotannins, lagerstroemin, and corosolic acid) in the green synthesis and capping of AuNPs. The green route synthesized AuNPs show strong photocatalytic activity in the reduction of dyes viz., methylene blue, methyl orange, bromophenol blue and bromocresol green, and 4-nitrophenol under visible light in the presence of NaBH 4 . The non-toxic and cost effective LSE mediated AuNPs synthesis proposed in this study is extremely rapid compared to the other reported methods that require hours to days for complete synthesis of AuNPs using various plant extracts. Strong and stable photocatalytic behavior makes AuNPs attractive in environmental applications, particularly in the reduction of organic pollutants in wastewater. Copyright © 2016. Published by Elsevier B.V.

  4. In vitro Effects of Four Native Brazilian Medicinal Plants in CYP3A4 mRNA Gene Expression, Glutathione Levels, and P-Glycoprotein Activity.

    PubMed

    Mazzari, Andre L D A; Milton, Flora; Frangos, Samantha; Carvalho, Ana C B; Silveira, Dâmaris; de Assis Rocha Neves, Francisco; Prieto, Jose M

    2016-01-01

    Erythrina mulungu Benth. (Fabaceae), Cordia verbenacea A. DC. (Boraginaceae), Solanum paniculatum L. (Solanaceae) and Lippia sidoides Cham. (Verbenaceae) are medicinal plant species native to Brazil shortlisted by the Brazilian National Health System for future clinical use. However, nothing is known about their effects in metabolic and transporter proteins, which could potentially lead to herb-drug interactions (HDI). In this work, we assess non-toxic concentrations (100 μg/mL) of the plant infusions for their in vitro ability to modulate CYP3A4 mRNA gene expression and intracellular glutathione levels in HepG2 cells, as well as P-glycoprotein (P-gp) activity in vincristine-resistant Caco-2 cells (Caco-2 VCR). Their mechanisms of action were further studied by measuring the activation of human pregnane X receptor (hPXR) in transiently co-transfected HeLa cells and the inhibition of γ-glutamyl transferase (GGT) in HepG2 cells. Our results show that P-gp activity was not affected in any case and that only Solanum paniculatum was able to significantly change CYP3A4 mRNA gene expression (twofold decrease, p < 0.05), this being correlated with an antagonist effect upon hPXR (EC50 = 0.38 mg/mL). Total intracellular glutathione levels were significantly depleted by exposure to Solanum paniculatum (-44%, p < 0.001), Lippia sidoides (-12%, p < 0.05) and Cordia verbenacea (-47%, p < 0.001). The latter plant extract was able to decrease GGT activity (-48%, p < 0.01). In conclusion, this preclinical study shows that the administration of some of these herbal medicines may be able to cause disturbances to metabolic mechanisms in vitro. Although Erythrina mulungu appears safe in our tests, active pharmacovigilance is recommended for the other three species, especially in the case of Solanum paniculatum.

  5. Canopy and leaf composition drive patterns of nutrient release from pruning residues in a coffee agroforest.

    PubMed

    Tully, Katherine L; Lawrence, Deborah

    2012-06-01

    In a coffee agroforest, the crop is cultivated under the shade of fruit-bearing and nitrogen (N)-fixing trees. These trees are periodically pruned to promote flowering and fruiting as well as to make nutrients stored in tree biomass available to plants. We investigated the effect of canopy composition and substrate quality on decomposition rates and patterns of nutrient release from pruning residues in a coffee agroforest located in Costa Rica's Central Valley. Initial phosphorus (P) release was enhanced under a canopy composed solely of N-fixing, Erythrina poeppigiana compared to a mixed canopy of Erythrina and Musa acuminata (banana). Both initial and final N release were similar under the two canopy types. However, after five months of decomposition, a higher proportion of initial N had been released under the single canopy. Although patterns of decomposition and nutrient release were not predicted by initial substrate quality, mass loss in leaf mixtures rates were well predicted by mean mass loss of their component species. This study identifies specific pruning regimes that may regulate N and P release during crucial growth periods, and it suggests that strategic pruning can enhance nutrient availability. For example, during the onset of rapid fruit growth, a two-species mixture may release more P than a three-species mixture. However, by the time of the harvest, the two- and three-species mixtures have released roughly the same amount of N and P. These nutrients do not always follow the same pattern, as N release can be maximized in single-species substrates, while P release is often facilitated in species mixtures. Our study indicates the importance of management practices in mediating patterns of nutrient release. Future research should investigate how canopy composition and farm management can also mediate on-farm nutrient losses.

  6. Fossil wood from the upper Miocene Mpesida Beds at Cheparain (Baringo District, Kenya): Botanical affinities and palaeoenvironmental implications

    NASA Astrophysics Data System (ADS)

    De Franceschi, Dario; Bamford, Marion; Pickford, Martin; Senut, Brigitte

    2016-03-01

    Seven wood samples from a petrified forest, in situ in ash flow deposits at Cheparain in the Tugen Hills (Kenya) in the Mpesida Beds, were discovered and studied. The age of the Mpesida Formation is estimated to be about 6.3 Ma on the basis of radio-isotope age determinations on the volcanic deposits, which overlie and underlie the sedimentary levels. The wood samples are mineralized with obvious sectors of differential mineralization, and different degrees of silica impregnation. All samples show heteroxylous structures corresponding to angiosperm dicotyledon trees. One sample consists in a half cylinder showing a well preserved mineralized structure of heteroxylous wood and probably corresponds to a fragment of root. This wood, with solitary (or in radial group) vessels, heterocellular multiseriate rays, paratracheal parenchyma in wide bands, and partly storied fusiform cells, clearly shows affinities with the genus Erythrina (Fabaceae). A slightly compressed branch, partly disturbed by injuries and highly mineralized shows solitary (or in short radial group) vessels, the rays uni-(bi) seriate are heterocellular, and the apotracheal parenchyma is in thin tangential bands. The closest affinities are with the genus Spirostachys (Euphorbiaceae). The other structures are poorly preserved (highly mineralized) and precise botanical affinities cannot be accessed. But the growth rings are distinct or diversely marked and the samples show semi-ring porous structures. They exhibit two different patterns. The growth rings reveal the presence of seasonal climate, and numerous injuries, a disturbance of the vegetation by animals and/or strong climatic events. Erythrina and Spirostachys are present in the extant vegetation of the Tana River Valley, in Kenya, which could represent a modern analogue for the vegetation of the Mpesida Beds prior to the major uplift of the Tugen Hills at the end of the Miocene.

  7. In vitro Effects of Four Native Brazilian Medicinal Plants in CYP3A4 mRNA Gene Expression, Glutathione Levels, and P-Glycoprotein Activity

    PubMed Central

    Mazzari, Andre L. D. A.; Milton, Flora; Frangos, Samantha; Carvalho, Ana C. B.; Silveira, Dâmaris; de Assis Rocha Neves, Francisco; Prieto, Jose M.

    2016-01-01

    Erythrina mulungu Benth. (Fabaceae), Cordia verbenacea A. DC. (Boraginaceae), Solanum paniculatum L. (Solanaceae) and Lippia sidoides Cham. (Verbenaceae) are medicinal plant species native to Brazil shortlisted by the Brazilian National Health System for future clinical use. However, nothing is known about their effects in metabolic and transporter proteins, which could potentially lead to herb-drug interactions (HDI). In this work, we assess non-toxic concentrations (100 μg/mL) of the plant infusions for their in vitro ability to modulate CYP3A4 mRNA gene expression and intracellular glutathione levels in HepG2 cells, as well as P-glycoprotein (P-gp) activity in vincristine-resistant Caco-2 cells (Caco-2 VCR). Their mechanisms of action were further studied by measuring the activation of human pregnane X receptor (hPXR) in transiently co-transfected HeLa cells and the inhibition of γ-glutamyl transferase (GGT) in HepG2 cells. Our results show that P-gp activity was not affected in any case and that only Solanum paniculatum was able to significantly change CYP3A4 mRNA gene expression (twofold decrease, p < 0.05), this being correlated with an antagonist effect upon hPXR (EC50 = 0.38 mg/mL). Total intracellular glutathione levels were significantly depleted by exposure to Solanum paniculatum (-44%, p < 0.001), Lippia sidoides (-12%, p < 0.05) and Cordia verbenacea (-47%, p < 0.001). The latter plant extract was able to decrease GGT activity (-48%, p < 0.01). In conclusion, this preclinical study shows that the administration of some of these herbal medicines may be able to cause disturbances to metabolic mechanisms in vitro. Although Erythrina mulungu appears safe in our tests, active pharmacovigilance is recommended for the other three species, especially in the case of Solanum paniculatum. PMID:27594838

  8. Stream chemistry modeling of two watersheds in the Front Range, Colorado

    USGS Publications Warehouse

    Meixner, Thomas; Bales, Roger C.; Williams, Mark W.; Campbell, Donald H.; Baron, Jill S.

    2000-01-01

    We investigated the hydrologic, geochemical, and biogeochemical controls on stream chemical composition on the Green Lakes Valley and Andrews Creek watersheds using the alpine hydrochemical model (AHM). Both sites had comparable data sets from 1994 and 1996, including high‐resolution spatial data and high‐frequency time series of hydrology, geochemistry, and meteorology. The model of each watershed consisted of three terrestrial subunits (soil, talus, and rock), with the routing between the subunits determined by spatial land cover data. Using 1994 data for model calibration and 1996 data for evaluation, AHM captured the dominant processes and successfully simulated daily stream chemical composition on both watersheds. These results confirm our procedure of using spatial and site‐specific field and laboratory data to generate an initial catchment model and then calibrating the model to calculate effective parameters for unmeasured processes. A net source of nitrogen was identified in the Andrews Creek watershed during the spring snowmelt period, whereas nitrogen was immobilized in the Green Lakes Valley. This difference was most likely due to the larger and more dominant area of talus in the Andrews Creek watershed. Our results also indicate that routing of snowmelt through either soil or talus material is sufficient for retention of H+ and release of base cations but that N retention is more important on areas mapped as soil. Owing to the larger ionic pulse and larger fraction of surface runoff the Green Lakes Valley was more sensitive to a doubling of wet deposition chemistry than the Andrews Creek watershed.

  9. Strength and fatigue of NT551 silicon nitride and NT551 diesel exhaust valves

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Andrews, M.J.; Werezczak, A.A.; Kirkland, T.P.

    2000-02-01

    The content of this report is excerpted from Mark Andrew's Ph.D. Thesis (Andrews, 1999), which was funded by a DOE/OTT High Temperature Materials Laboratory Graduate Fellowship. It involves the characterization of NT551 and valves fabricated with it. The motivations behind using silicon nitride (Si{sub 3}N{sub 4}) as an exhaust valve for a diesel engine are presented in this section. There are several economic factors that have encouraged the design and implementation of ceramic components for internal combustion (IC) engines. The reasons for selecting the diesel engine valve for this are also presented.

  10. Timescales for migration of atmospherically derived sulphate through an alpine/subalpine watershed, Loch Vale Colorado

    USGS Publications Warehouse

    Michel, Robert L.; Campbell, Donald H.; Clow, David W.; Turk, John T.

    2000-01-01

    Sulphur 35, a cosmogenically produced radioisotope with a short half‐life (87 days), was measured in snowpack during 1993–1997 and at four locations within the Loch Vale watershed during 1995–1997. The four sites include the two main drainages in the watershed, Andrews Creek and Icy Brook, a small south facing catchment flowing into Andrews Creek (Andrews Spring 1), and a similar north facing catchment flowing out of a scree field into Icy Brook (Spring 19). Concentrations ranged from a high of almost 50 mBq/L for a sample from Spring 19 in June 1996 to a concentration near the detection limit for a sample from Andrews Creek in April 1997. Sulphur 35 concentrations were normalized to sulphate (as mBq/mg SO4−2) and were decay‐corrected to a Julian day of 90 (April 1) for each year. Snowpack had the highest 35S concentration with an average concentration of 53 mBq/mg SO4−2. Concentrations in the streams were much lower, even when corrected for decay relative to JD 90. The large 35S concentrations found in Spring 19 were the result of increases in concentration due to sublimation and/or evapotranspiration and were lower than snowpack when normalized to sulphate. Using 35S concentrations found in snowpack as of JD 90 as a beginning concentration, the fraction of sulphate in streamflow that was derived from atmospheric deposition within the prior water year was estimated. For Icy Brook and Andrews Creek the fraction of the sulphate in streamflow derived from that year's snowpack and precipitation was low prior to the beginning of the main spring melt, reached a maximum during the period of maximum flow, and decreased as the summer progressed. A calculation of the seasonal flux indicated that about 40% of the sulphate that flowed out of the watershed was derived from atmospheric sulphate deposited during the previous year. This suggests that more than half of the sulphate deposited in the watershed by atmospheric processes during the previous year was

  11. KENNEDY SPACE CENTER, FLA. - The STS-114 crew gathers around the work stand holding the insert for Discovery’s nose cap. From left are Mission Specialists Soichi Noguchi, and Charles Camarda; Commander Eileen Collins; Mission Specialists Andrew Thomas and Wendy Lawrence; Pilot James Kelly; and Mission Specialist Stephen Robinson. Noguchi represents the Japanese Aerospace and Exploration Agency. The insert is being fitted with thermal protection system insulation blankets. The crew is spending time becoming familiar with Shuttle and mission equipment. The mission is Logistics Flight 1, which is scheduled to deliver supplies and equipment plus the external stowage platform to the International Space Station.

    NASA Image and Video Library

    2004-03-05

    KENNEDY SPACE CENTER, FLA. - The STS-114 crew gathers around the work stand holding the insert for Discovery’s nose cap. From left are Mission Specialists Soichi Noguchi, and Charles Camarda; Commander Eileen Collins; Mission Specialists Andrew Thomas and Wendy Lawrence; Pilot James Kelly; and Mission Specialist Stephen Robinson. Noguchi represents the Japanese Aerospace and Exploration Agency. The insert is being fitted with thermal protection system insulation blankets. The crew is spending time becoming familiar with Shuttle and mission equipment. The mission is Logistics Flight 1, which is scheduled to deliver supplies and equipment plus the external stowage platform to the International Space Station.

  12. Seeing the Light (LBNL Science at the Theater)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brunger, Axel; Segalman, Rachel; Westphal, Andrew

    2011-09-12

    Berkeley Lab's Science at the Theater event "Seeing the Light" took place on Sept 12, 2011, at Berkeley Repertory's Roda Theatre. Learn how the Advanced Light Source is improving medicine, paving the way for clean energy, changing the future of computers, and much more. Featured speakers are Berkeley Lab's Roger Falcone, Rachel Segalman, Andrew Westphal, and Stanford University's Axel Brunger. Rachel Segalman: The future of clean energy technology relies on a better understanding of materials at the nanoscale. Berkeley Lab's Rachel Segalman uses the ALS to conduct this research, which could lead to improved photovoltaics and fuel cells. Axel Brunger:more » Improved treatment for human diseases hinges on understanding molecular-scale processes. Stanford University's Axel Brunger will discuss a new melanoma drug that was developed by a local company, Plexxikon, using the ALS for X-ray data collection. Andrew Westphal: What's comet dust made of? Andrew Westphal of UC Berkeley's Space Sciences Laboratory uses the ALS to study comet dust and interplanetary space dust collected by a NASA spacecraft. Moderated by Roger Falcone, Division Director of the Advanced Light Source« less

  13. "On the margins": A dialogue with Andrew Greeley.

    PubMed

    Moss, D M

    1990-12-01

    This dialogue is between two priests who share common interests from different perspectives. One is an Episcopalian and a psychoanalytic psychotherapist. The other is a Roman Catholic and a sociologist widely known for his controversial novels and political commentaries. Their conversation primarily focuses on the latter's ministry-especially his investigations into paranormal experiences and his use of fiction as a homiletical avenue. They also discuss: Christian atheism; the Resurrection as a metaphor; Real Presence and liturgical sensibility; contemporary ecumenical trends; celibacy and tenures of active ministry; sexual equality and population control; religious addiction; and examples of the mythic impact of cinema.

  14. A resolution honoring the life of Andrew Wyeth.

    THOMAS, 111th Congress

    Sen. Casey, Robert P., Jr. [D-PA

    2009-01-27

    Senate - 01/27/2009 Submitted in the Senate, considered, and agreed to without amendment and with a preamble by Unanimous Consent. (All Actions) Tracker: This bill has the status Agreed to in SenateHere are the steps for Status of Legislation:

  15. Analysis of Advanced CI Applications

    DTIC Science & Technology

    1981-03-01

    rner Street Boston, ,/iA 021 10 Atcn« L,r. Fred Quelle AF^L/Of (ianscum AHB, MA 01/31 Atun « ./r. John Oanny AF..L/AL0 Kirtiand AHB...M d/11 / Atun « .jr. J. d. Hoyye ArJC/OL Andrew^ Ar’d, DO 20.334 Atv,n« oapt Oyole AFdC/X^rU Andrews Af-d, ÜO 20334 8 10 II...8217’■ ..:., ■■ . >. ■ — Ini Mil/Li;icoin Lab H. ). üux l-i Le ; in ji-on, MA U^l /.j Atun » iJr. ü. üreenwooj 4U Naval

  16. Anti-bacterial activity of some Brazilian medicinal plants.

    PubMed

    de Lima, Maria Raquel Ferreira; de Souza Luna, Josiane; dos Santos, Aldenir Feitosa; de Andrade, Maria Cristina Caño; Sant'Ana, Antônio Euzébio Goulart; Genet, Jean-Pierre; Marquez, Béatrice; Neuville, Luc; Moreau, Nicole

    2006-04-21

    Extracts from various organs of 25 plants of Brazilian traditional medicine were assayed with respect to their anti-bacterial activities against Escherichia coli, a susceptible strain of Staphylococcus aureus and two resistant strains of Staphylococcus aureus harbouring the efflux pumps NorA and MsrA. Amongst the 49 extracts studied, 14 presented anti-bacterial activity against Staphylococcus aureus, including the ethanolic extracts from the rhizome of Jatropha elliptica, from the stem barks of Schinus terebinthifolius and Erythrina mulungu, from the stems and leaves of Caesalpinia pyramidalis and Serjania lethalis, and from the stem bark and leaves of Lafoensia pacari. The classes of compounds present in the active extracts were determined as a preliminary step towards their bioactivity-guided separation. No extracts were active against Escherichia coli.

  17. Biochemical Benefits, Diagnosis, and Clinical Risks Evaluation of Kratom.

    PubMed

    Fluyau, Dimy; Revadigar, Neelambika

    2017-01-01

    Kratom ( Mitragyna speciosa ) is a tropical tree with a long history of traditional use in parts of Africa and Southeast Asia. Kratom is also known as Thom, Thang, and Biak. Its leaves and the teas brewed from them have long been used by people in that region to manage pain and opioid withdrawal and to stave off fatigue. Kratom is actually consumed throughout the world for its stimulant effects and as an opioid substitute (in form of tea, chewed, smoked, or ingested in capsules). Some case reports have associated kratom exposure with psychosis, seizures, intrahepatic cholestasis, other medical conditions, and deaths. The clinical manifestations of kratom effects are not well defined and the clinical studies are limited. Data research suggest that both stimulant and sedative dose-dependent effects do exist, in addition to antinociceptive, antidepressant activity, anxiolytic-like effects, and anorectic effects, but a growing concern for the drug's effects and safety of use has resulted in national and international attention primarily due to an increase in hospital visits and deaths in several countries that are believed to have been caused by extracts of the plant. There is a dearth of double blind controlled studies. In this study, we aim to use existing literature to clarify both benefits and risks of kratom as well as its diagnosis evaluation as kratom misuse is an emerging trend in the Western world. Literature review using databases such as Embase, Medline, PubMed, Cochrane Library, and Mendeley from 2007 to 2017 were evaluated by all authors to analyze current state on benefits, risks, and diagnosis evaluation of kratom ( M. speciosa ). Data analysis suggested that kratom possesses some benefits such as stimulant and sedative effects as wells as antinociceptive effects. It seems to inhibit pro-inflammatory mediator release and vascular permeability and can enhance immunity. In addition, it may be an antidepressant and anorectic. However, kratom can cause

  18. 76 FR 66103 - In the Matter of NASDAQ OMX BX, Inc.: Order Denying NASDAQ OMX BX, Inc.'s Petition for Review of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-25

    ... Securities LLC (``Citadel''), dated August 12, 2011 (``Citadel Letter''); Andrew Stevens, Legal Counsel, IMC Financial Markets (``IMC''), dated August 15, 2011 (``IMC Letter''); Michael J. Simon, Secretary...

  19. Long-Term Effects of Red- and Blue-Light Emitting Diodes on Leaf Anatomy and Photosynthetic Efficiency of Three Ornamental Pot Plants

    PubMed Central

    Zheng, Liang; Van Labeke, Marie-Christine

    2017-01-01

    Light quality critically affects plant development and growth. Development of light-emitting diodes (LEDs) enables the use of narrow band red and/or blue wavelengths as supplementary lighting in ornamental production. Yet, long periods under these wavelengths will affect leaf morphology and physiology. Leaf anatomy, stomatal traits, and stomatal conductance, leaf hydraulic conductance (Kleaf), and photosynthetic efficiency were investigated in three ornamental pot plants, namely Cordyline australis (monocot), Ficus benjamina (dicot, evergreen leaves), and Sinningia speciosa (dicot, deciduous leaves) after 8 weeks under LED light. Four light treatments were applied at 100 μmol m−2 s−1 and a photoperiod of 16 h using 100% red (R), 100% blue (B), 75% red with 25% blue (RB), and full spectrum white light (W), respectively. B and RB resulted in a greater maximum quantum yield (Fv/Fm) and quantum efficiency (ΦPSII) in all species compared to R and W and this correlated with a lower biomass under R. B increased the stomatal conductance compared with R. This increase was linked to an increasing stomatal index and/or stomatal density but the stomatal aperture area was unaffected by the applied light quality. Leaf hydraulic conductance (Kleaf) was not significantly affected by the applied light qualities. Blue light increased the leaf thickness of F. benjamina, and a relative higher increase in palisade parenchyma was observed. Also in S. speciosa, increase in palisade parenchyma was found under B and RB, though total leaf thickness was not affected. Palisade parenchyma tissue thickness was correlated to the leaf photosynthetic quantum efficiency (ΦPSII). In conclusion, the role of blue light addition in the spectrum is essential for the normal anatomical leaf development which also impacts the photosynthetic efficiency in the three studied species. PMID:28611818

  20. The pharmacology and toxicology of kratom: from traditional herb to drug of abuse.

    PubMed

    Warner, Marcus L; Kaufman, Nellie C; Grundmann, Oliver

    2016-01-01

    Mitragyna speciosa (Rubiaceae), commonly known as kratom, is a tropical tree with a long history of traditional use in parts of Africa and Southeast Asia. In recent years, kratom has gained popularity for use as a recreational drug across the globe. Relatively new to the illicit market and used in a manner different from its traditional applications, preparations of kratom are touted by many as a safe and legal psychoactive product that improves mood, relieves pain, and may provide benefits in opiate addiction. Available literature was reviewed for M. speciosa via PubMed, Google Scholar, CINAHL, and EBSCO to summarize its traditional uses, phytochemical composition, pharmacology and toxicology of proposed active constituents, and potential for misuse and abuse. Research has demonstrated that both stimulant and sedative dose-dependent effects do exist, but a growing concern for the drug's effects and safety of use has resulted in national and international attention primarily due to an increase in hospital visits and deaths in several countries that are said to have been caused by extracts of the plant. The main active alkaloid substances in kratom, mitragynine and 7-hydroxymitragynine, present with a range of CNS stimulant and depressant effects mediated primarily through monoaminergic and opioid receptors. Recently, Palm Beach County, located in the southeastern corridor of Florida, has considered regulating kratom due to public safety concerns following the death of a young adult. At the local, state, and even federal levels, governments are now being confronted with the task of determining the safety and the possible regulation of kratom extracts. There are currently no standard analytical screening techniques for mitragynine and its metabolites following ingestion limiting its detection to more sophisticated techniques like liquid chromatography-mass spectrometry to determine kratom use. The growing concern of the abuse potential of kratom requires careful

  1. Comparative embryology of eleven species of stony corals (Scleractinia).

    PubMed

    Okubo, Nami; Mezaki, Takuma; Nozawa, Yoko; Nakano, Yoshikatsu; Lien, Yi-Ting; Fukami, Hironobu; Hayward, David C; Ball, Eldon E

    2013-01-01

    A comprehensive understanding of coral reproduction and development is needed because corals are threatened in many ways by human activity. Major threats include the loss of their photosynthetic symbionts (Symbiodinium) caused by rising temperatures (bleaching), reduced ability to calcify caused by ocean acidification, increased storm severity associated with global climate change and an increase in predators caused by runoff from human agricultural activity. In spite of these threats, detailed descriptions of embryonic development are not available for many coral species. The current consensus is that there are two major groups of stony corals, the "complex" and the "robust". In this paper we describe the embryonic development of four "complex" species, Pseudosiderastrea tayamai, Galaxea fascicularis, Montipora hispida, and Pavona Decussata, and seven "robust" species, Oulastrea crispata, Platygyra contorta, Favites abdita, Echinophyllia aspera, Goniastrea favulus, Dipsastraea speciosa (previously Favia speciosa), and Phymastrea valenciennesi (previously Montastrea valenciennesi). Data from both histologically sectioned embryos and whole mounts are presented. One apparent difference between these two major groups is that before gastrulation the cells of the complex corals thus far described (mainly Acropora species) spread and flatten to produce the so-called prawn chip, which lacks a blastocoel. Our present broad survey of robust and complex corals reveals that prawn chip formation is not a synapomorphy of complex corals, as Pavona Decussata does not form a prawn chip and has a well-developed blastocoel. Although prawn chip formation cannot be used to separate the two clades, none of the robust corals which we surveyed has such a stage. Many robust coral embryos pass through two periods of invagination, separated by a return to a spherical shape. However, only the second of these periods is associated with endoderm formation. We have therefore termed the first

  2. Long-Term Effects of Red- and Blue-Light Emitting Diodes on Leaf Anatomy and Photosynthetic Efficiency of Three Ornamental Pot Plants.

    PubMed

    Zheng, Liang; Van Labeke, Marie-Christine

    2017-01-01

    Light quality critically affects plant development and growth. Development of light-emitting diodes (LEDs) enables the use of narrow band red and/or blue wavelengths as supplementary lighting in ornamental production. Yet, long periods under these wavelengths will affect leaf morphology and physiology. Leaf anatomy, stomatal traits, and stomatal conductance, leaf hydraulic conductance (K leaf ), and photosynthetic efficiency were investigated in three ornamental pot plants, namely Cordyline australis (monocot), Ficus benjamina (dicot, evergreen leaves), and Sinningia speciosa (dicot, deciduous leaves) after 8 weeks under LED light. Four light treatments were applied at 100 μmol m -2 s -1 and a photoperiod of 16 h using 100% red (R), 100% blue (B), 75% red with 25% blue (RB), and full spectrum white light (W), respectively. B and RB resulted in a greater maximum quantum yield (F v /F m ) and quantum efficiency (Φ PSII ) in all species compared to R and W and this correlated with a lower biomass under R. B increased the stomatal conductance compared with R. This increase was linked to an increasing stomatal index and/or stomatal density but the stomatal aperture area was unaffected by the applied light quality. Leaf hydraulic conductance (K leaf ) was not significantly affected by the applied light qualities. Blue light increased the leaf thickness of F. benjamina , and a relative higher increase in palisade parenchyma was observed. Also in S. speciosa , increase in palisade parenchyma was found under B and RB, though total leaf thickness was not affected. Palisade parenchyma tissue thickness was correlated to the leaf photosynthetic quantum efficiency (Φ PSII ). In conclusion, the role of blue light addition in the spectrum is essential for the normal anatomical leaf development which also impacts the photosynthetic efficiency in the three studied species.

  3. Comparative Embryology of Eleven Species of Stony Corals (Scleractinia)

    PubMed Central

    Okubo, Nami; Mezaki, Takuma; Nozawa, Yoko; Nakano, Yoshikatsu; Lien, Yi-Ting; Fukami, Hironobu; Hayward, David C.; Ball, Eldon E.

    2013-01-01

    A comprehensive understanding of coral reproduction and development is needed because corals are threatened in many ways by human activity. Major threats include the loss of their photosynthetic symbionts (Symbiodinium) caused by rising temperatures (bleaching), reduced ability to calcify caused by ocean acidification, increased storm severity associated with global climate change and an increase in predators caused by runoff from human agricultural activity. In spite of these threats, detailed descriptions of embryonic development are not available for many coral species. The current consensus is that there are two major groups of stony corals, the "complex" and the "robust". In this paper we describe the embryonic development of four "complex" species, Pseudosiderastrea tayamai, Galaxea fascicularis, Montipora hispida, and Pavona Decussata, and seven "robust" species, Oulastrea crispata, Platygyra contorta, Favites abdita, Echinophyllia aspera, Goniastrea favulus, Dipsastraea speciosa (previously Favia speciosa), and Phymastrea valenciennesi (previously Montastrea valenciennesi). Data from both histologically sectioned embryos and whole mounts are presented. One apparent difference between these two major groups is that before gastrulation the cells of the complex corals thus far described (mainly Acropora species) spread and flatten to produce the so-called prawn chip, which lacks a blastocoel. Our present broad survey of robust and complex corals reveals that prawn chip formation is not a synapomorphy of complex corals, as Pavona Decussata does not form a prawn chip and has a well-developed blastocoel. Although prawn chip formation cannot be used to separate the two clades, none of the robust corals which we surveyed has such a stage. Many robust coral embryos pass through two periods of invagination, separated by a return to a spherical shape. However, only the second of these periods is associated with endoderm formation. We have therefore termed the first

  4. 75 FR 78777 - Advisory Committee On Reactor Safeguards; Renewal

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-16

    ... Committee includes individuals experienced in reactor operations, management; probabilistic risk assessment...: December 10, 2010. Andrew L. Bates, Advisory Committee Management Officer. [FR Doc. 2010-31590 Filed 12-15...

  5. 77 FR 50691 - Request for Information (RFI): Guidance on Data Streamlining and Reducing Undue Reporting Burden...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-22

    .... Attention: HIV Data Streamlining. FOR FURTHER INFORMATION CONTACT: Andrew D. Forsyth Ph.D. or Vera... of HIV/AIDS programs that vary in their specifications (e.g., numerators, denominators, time frames...

  6. 78 FR 53426 - Expansion of Foreign-Trade Zone 84; Houston, Texas

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-29

    ..., and further subject to sunset provisions that would terminate authority on August 31, 2018, for Sites... Commerce for Import Administration, Alternate Chairman, Foreign-Trade Zones Board. ATTEST: Andrew McGilvray...

  7. Patents of drugs extracted from Brazilian medicinal plants.

    PubMed

    Balbani, Aracy P S; Silva, Dulce H S; Montovani, Jair C

    2009-04-01

    Plants synthesise a vast repertoire of chemicals with various biological activities. Brazilian enormous botanical diversity facilitates the development of novel ethical drugs for the treatment of diseases in humans. To present therapeutic patent applications comprising Brazilian native plants published in the 2003-2008 period in light of legal aspects of patentability of biodiversity and public health concerns. Therapeutic patent applications related to Brazilian medicinal plants available at both the European Patent Office and the Brazilian National Institute of Industrial Property databases were reviewed. Twenty-five patents are presented, most of which concern inflammatory, allergic, parasitic, infectious or digestive diseases, including extracts from Carapa guianensis, Copaifera genus, Cordia verbenacea, Erythrina mulungu, Physalis angulata and other pharmaceutical compositions with antileishmanial, antimalarial or trypanocidal activity. Brazilian research centres and universities are responsible for most of these inventions.

  8. KENNEDY SPACE CENTER, FLA. - STS-114 Mission Specialist Charles Camarda (left) watches as Mission Specialist Andrew Thomas manipulates equipment that will be used on the mission. Crew members are at KSC for equipment familiarization. STS-114 is classified as Logistics Flight 1 to the International Space Station, delivering new supplies and replacing one of the orbital outpost’s Control Moment Gyroscopes (CMGs). STS-114 will also carry a Raffaello Multi-Purpose Logistics Module and the External Stowage Platform-2. The crew is slated to conduct at least three spacewalks: They will demonstrate repair techniques of the Shuttle’s Thermal Protection System, replace the failed CMG with one delivered by the Shuttle, and install the External Stowage Platform.

    NASA Image and Video Library

    2004-01-27

    KENNEDY SPACE CENTER, FLA. - STS-114 Mission Specialist Charles Camarda (left) watches as Mission Specialist Andrew Thomas manipulates equipment that will be used on the mission. Crew members are at KSC for equipment familiarization. STS-114 is classified as Logistics Flight 1 to the International Space Station, delivering new supplies and replacing one of the orbital outpost’s Control Moment Gyroscopes (CMGs). STS-114 will also carry a Raffaello Multi-Purpose Logistics Module and the External Stowage Platform-2. The crew is slated to conduct at least three spacewalks: They will demonstrate repair techniques of the Shuttle’s Thermal Protection System, replace the failed CMG with one delivered by the Shuttle, and install the External Stowage Platform.

  9. KENNEDY SPACE CENTER, FLA. - STS-114 Mission Specialist Andrew Thomas works on equipment in the Space Station Processing Facility. He and other crew members are at KSC for equipment familiarization. STS-114 is classified as Logistics Flight 1 to the International Space Station, delivering new supplies and replacing one of the orbital outpost’s Control Moment Gyroscopes (CMGs). STS-114 will also carry a Raffaello Multi-Purpose Logistics Module and the External Stowage Platform-2. The crew is slated to conduct at least three spacewalks: They will demonstrate repair techniques of the Shuttle’s Thermal Protection System, replace the failed CMG with one delivered by the Shuttle, and install the External Stowage Platform.

    NASA Image and Video Library

    2004-01-27

    KENNEDY SPACE CENTER, FLA. - STS-114 Mission Specialist Andrew Thomas works on equipment in the Space Station Processing Facility. He and other crew members are at KSC for equipment familiarization. STS-114 is classified as Logistics Flight 1 to the International Space Station, delivering new supplies and replacing one of the orbital outpost’s Control Moment Gyroscopes (CMGs). STS-114 will also carry a Raffaello Multi-Purpose Logistics Module and the External Stowage Platform-2. The crew is slated to conduct at least three spacewalks: They will demonstrate repair techniques of the Shuttle’s Thermal Protection System, replace the failed CMG with one delivered by the Shuttle, and install the External Stowage Platform.

  10. Received and perceived social support in times of stress: a test of the social support deterioration deterrence model.

    PubMed

    Norris, F H; Kaniasty, K

    1996-09-01

    The authors evaluated the impact of receiving social support on subsequent levels of perceived social support and psychological distress in 2 independent samples of victims of severe natural disasters: Hurricane Hugo (n = 498) and Hurricane Andrew (n = 404). A social support deterioration deterrence model was proposed that stipulated that postdisaster mobilization of received support counteracts the deterioration in expectations of support often experienced by victims of major life events. LISREL analyses of data collected 12 and 24 months after Hugo and 6 and 28 months after Andrew provided strong evidence for the hypothesized model: Perceived support mediated the long-term effects on distress of both scope of disaster exposure and postdisaster received support. Theoretical and application issues of social support are discussed.

  11. Revision of genus Pericalus from China, with descriptions of four new species (Carabidae, Lebiini, Pericalina).

    PubMed

    Shi, Hongliang; Liang, Hongbin

    2018-01-01

    Nine taxa of the genus Pericalus Macleay from China are revised, with four new species described: Pericalus gibbosus sp. n. (type locality: Putao, Myanmar; one paratype from Mêdog, Xizang), Pericalus elegans sp. n. (type locality: Mêdog, Xizang), Pericalus acutidens sp. n. (type locality: Longchuan, Yunnan), and Pericalus obscuratus sp. n. (type locality: Fanjingshan, Guizhou). Four taxa are newly recorded from China: Pericalus ornatus ornatus Schmidt-Göbel (Yunnan, Hainan), P. obtusipennis Fedorenko (Yunnan), P. amplus Andrewes (Yunnan), and P. dux Andrewes (Yunnan). Pericalus formosanus Dupuis is newly ranked as a subspecies of P. ornatus Schmidt-Göbel. An improved key to world species of the subgenus Pericalus is provided, along with distribution maps and images of habitus and male and female genitalia for all Chinese species.

  12. 77 FR 52695 - National Sea Grant Advisory Board

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-30

    ... on the National Sea Grant College Program Web site at http://www.seagrant.noaa.gov/leadership....seagrant.noaa.gov/leadership/advisory_board.html . Dated: August 24, 2012. Andrew Baldus, Acting Chief...

  13. Transient Simulation of a Rotating Conducting Cylinder in a Transverse Magnetic Field

    DTIC Science & Technology

    2016-09-01

    GIDEP Operations Center P.O. Box 8000 Corona , CA 91718-8000 gidep@gidep.org UNCLASSIFIED Approved for public release; distribution is unlimited. UNCLASSIFIED 26 Douglas C. Troast Douglas C. Troast Andrew Pskowski

  14. 6. Historic American Buildings Survey, August, 1966 REAR PORCH SHOWING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Historic American Buildings Survey, August, 1966 REAR PORCH SHOWING BALCONY WHICH GIVES ACCESS TO SECOND FLOOR ROOMS. - Andrews-Taylor House, State Route 43, Farm Road 2862 Vicinity, Karnack, Harrison County, TX

  15. The African Women's Protocol: bringing attention to reproductive rights and the MDGs.

    PubMed

    Gerntholtz, Liesl; Gibbs, Andrew; Willan, Samantha

    2011-04-01

    Andrew Gibbs and colleagues discuss the African Women's Protocol, a framework for ensuring reproductive rights are supported throughout the continent and for supporting interventions to improve women's reproductive health, including the MDGs.

  16. Application of Andrew's Plots to Visualization of Multidimensional Data

    ERIC Educational Resources Information Center

    Grinshpun, Vadim

    2016-01-01

    Importance: The article raises a point of visual representation of big data, recently considered to be demanded for many scientific and real-life applications, and analyzes particulars for visualization of multi-dimensional data, giving examples of the visual analytics-related problems. Objectives: The purpose of this paper is to study application…

  17. General Christopher C. Andrews: Leading the Minnesota Forestry Revolution

    ERIC Educational Resources Information Center

    Rice, Anna M.

    2002-01-01

    In the nineteenth century, America's burgeoning population certainly did grab all the timber it could. Vast pine forests stretched from Maine to Dakota, and the lumber industry voraciously consumed them from east to west. In 1800, the Minnesota territory was sparsely sprinkled with fur traders and American Indians. By 1850, its bounteous forests…

  18. 76 FR 30109 - Marine Mammals; File No. 15453

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-24

    ... hereby given that the Waikiki Aquarium, 2777 Kalakaua Avenue Honolulu, HI 96815 (Dr. Andrew Rossiter... Blvd., Rm 1110, Honolulu, HI 96814-4700; phone (808)944-2200; fax (808)973-2941. Written comments on...

  19. 5. View of rear, side and collapsed porch with well. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. View of rear, side and collapsed porch with well. Photographer facing west by northwest, 300 degrees. - Andrew Nations House, Northeast corner of intersection of Redwing & Bernhard Roads, Peachtree City, Fayette County, GA

  20. Cyberpower as a Coercive Instrument

    DTIC Science & Technology

    2009-06-01

    weaknesses. Members 10 Lech Janczewski and Andrew M. Colarik, Cyber Warfare and Cyber Terrorism, (Idea...Polity Press, 2004. 66 Freedman, Lawrence. Strategic Coercion: Concepts and Cases, Oxford: Oxford University Press, 1998. Janczewski, Lech

  1. 3. VIEW OF EAST SIDE AND NORTH FRONT OF BUILDING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. VIEW OF EAST SIDE AND NORTH FRONT OF BUILDING #2205 (AREA CONTAINING VEHICLE REPAIR SHOP AND VEHICLE MANAGEMENT OFFICE), FACING SOUTHWEST. - Medford Service Center, Warehouse, 1319 McAndrews Road, Medford, Jackson County, OR

  2. 20. Photocopy of photograph (original in the Langley Research Center ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. Photocopy of photograph (original in the Langley Research Center Archives, Hampton, VA AERIAL VIEW OF THE SEAPLANE TOWING CHANNEL STRUCTURE. - NASA Langley Research Center, Seaplane Towing Channel, 108 Andrews Street, Hampton, Hampton, VA

  3. Physical medicine and rehabilitation

    MedlinePlus

    ... WR, Silver JK, Rizzo TD, eds. Essentials of Physical Medicine and Rehabilitation: Musculoskeletal Disorders, Pain, and Rehabilitation . 3rd ed. Philadelphia, PA: Elsevier Saunders; 2015. Review Date 10/23/2017 Updated by: Andrew W. ...

  4. 7. Historic American Buildings Survey, August, 1966 EXTERIOR STAIR TO ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Historic American Buildings Survey, August, 1966 EXTERIOR STAIR TO SECOND FLOOR, SHOWING PASSAGE BETWEEN MAIN BLOCK AND REAR ELL. - Andrews-Taylor House, State Route 43, Farm Road 2862 Vicinity, Karnack, Harrison County, TX

  5. Living with hearing loss

    MedlinePlus

    ... independent Be safer wherever you are Managing the Environment Many things in your surroundings can affect how ... hearing loss . References Andrews J. Optimizing the built environment for frail older adults. In: Fillit HM, Rockwood ...

  6. 47. Jet Lowe, Photographer, June 1978. STAFFORD LOOM, WITH R. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    47. Jet Lowe, Photographer, June 1978. STAFFORD LOOM, WITH R. W. ANDREWS PATENT PATTERN DEVICE, C. 1870, VIEW LOOKING FROM THE FRONT, SECOND FLOOR SOUTH. - Watkins Mill, County Highway MM, Lawson, Ray County, MO

  7. 78 FR 41058 - FFP Missouri 2, LLC; Notice of Proposed Restricted Service List For a Programmatic Agreement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-09

    ... Brown, Chickasaw Nation, Department of Archives and P.O. Box 1548, Ada, OK 74821. History, 100 South State Street, Jackson, MS 39201 Andrew Tomlinson, U.S. Army Corps Kenneth H. Carlton, THPO, of Engineers...

  8. Biogeochemical Process Comparison of the Five USGS Water, Energy, and Biogeochemical Budget (WEBB) Sites

    NASA Astrophysics Data System (ADS)

    Shanley, J. B.; Peters, N. E.; Aulenbach, B. T.; Blum, A. E.; Campbell, D. H.; Clow, D. W.; Larsen, M. C.; Mast, M. A.; Stallard, R. F.; Troester, J. W.; Walker, J. F.; Webb, R. M.; White, A. F.

    2001-12-01

    Input - output budgets (in wet deposition and streamwater) have been constructed for water and major solutes at the five USGS Water, Energy, and Biogeochemical Budget (WEBB) sites for the period 1992-97 (Peters et al., 2000). In this poster we interpret the net chemical fluxes to identify the controlling biogeochemical processes, as influenced by the strong physical and biological contrasts (climate, geology, physiography, and vegetation types) in the five diverse environments. The five sites are: Allequash Creek, Wisconsin (low-relief humid continental forest); Andrews Creek, Colorado (cold alpine, taiga/tundra, and subalpine boreal forest); Icacos River, Puerto Rico (lower montane, wet tropical forest); Panola Mountain, Georgia (humid subtropical piedmont forest); and Sleepers River, Vermont (humid northern hardwood forest). Base cations and Si produced by chemical weathering displayed a net export at each site. The magnitude and stoichiometry of export reflects mineralogy, climate (temperature and rainfall), and water residence time in the subsurface. The lowest and highest mass export generally was for Andrews Creek and Icacos River, respectively, consistent with their extreme mean annual temperatures (0/degC in Colorado to 21/degC in Puerto Rico) and the limited residence time of meltwater at Andrews Creek. Calcite in bedrock at the three coldest watersheds caused somewhat higher relative export of Ca, especially at Sleepers River where calcite weathering is a dominant control on stream chemistry. In contrast, the high Mg content of the volcaniclastic rocks at Icacos River and glacial deposits at Allequash Creek caused disproportionately high Mg export relative to the other sites. Relatively high Na export at Panola Mountain and K export at Sleepers River are probably caused by plagioclase and biotite weathering, respectively. SO4 is retained at the two warmest sites, Panola Mountain and Icacos River. SO4 adsorption is known to limit SO4- export in highly

  9. MOCR activity during Day 6 of STS-3 mission

    NASA Technical Reports Server (NTRS)

    1982-01-01

    Andrew A. Fullerton, the six-year-old son of STS-3 pilot C. Gordon Fullerton, watches a television monitor in the mission control center's viewing room (28802); Mrs. Marie J. Fullerton in the mission control center's viewing room. Other members of the STS-3 pilot's family are seated on each side of Mrs. Fullerton. His sister, Jeanne Dockham, is at left foreground; son Andrew A., at right foreground. Mr. and Mrs. E. G. Buettner, Mrs. Fullerton's parents, are seated at center, and beyond them is Mrs. Charles R. Fullerton, the astronaut's mother (28803); Mary Ann Austin seated at the remote manipulator sytem (RMS) console in the mission operations control room (MOCR) shares the scene with a representation of a 1/15-scale model of the Canadian-built remote manipulator system arm (28804).

  10. Revision of genus Pericalus from China, with descriptions of four new species (Carabidae, Lebiini, Pericalina)

    PubMed Central

    Shi, Hongliang; Liang, Hongbin

    2018-01-01

    Abstract Nine taxa of the genus Pericalus Macleay from China are revised, with four new species described: Pericalus gibbosus sp. n. (type locality: Putao, Myanmar; one paratype from Mêdog, Xizang), Pericalus elegans sp. n. (type locality: Mêdog, Xizang), Pericalus acutidens sp. n. (type locality: Longchuan, Yunnan), and Pericalus obscuratus sp. n. (type locality: Fanjingshan, Guizhou). Four taxa are newly recorded from China: Pericalus ornatus ornatus Schmidt-Göbel (Yunnan, Hainan), P. obtusipennis Fedorenko (Yunnan), P. amplus Andrewes (Yunnan), and P. dux Andrewes (Yunnan). Pericalus formosanus Dupuis is newly ranked as a subspecies of P. ornatus Schmidt-Göbel. An improved key to world species of the subgenus Pericalus is provided, along with distribution maps and images of habitus and male and female genitalia for all Chinese species. PMID:29844711

  11. Systemic Metabolic Derangement, Pulmonary Effects, and Insulin Insufficiency Following Subchronic Ozone Exposure in Rats

    EPA Pesticide Factsheets

    This data set includes individual animal data collected for various biological endpoints that are included in the manuscript.Miller DB, Snow SJ, Henriquez A, Schladweiler MC, Ledbetter AD, Richards JE, Andrews DL, Kodavanti UP. Systemic metabolic derangement, pulmonary effects, and insulin insufficiency following subchronic ozone exposure in rats. Toxicol Appl Pharmacol. 2016 Jun 28;306:47-57. The primary author Desinia Miller, an UNC-EPA co-opp Student has since completed her PhD and is no longer in EPA database.This dataset is associated with the following publication:Miller, D., S. Snow, A. Henriquez, M. Schladweiler, A. Ledbetter, J. Richards, D. Andrews, and U. Kodavanti. Systemic Metabolic Derangement, Pulmonary Effects, and Insulin Insufficiency following subchronic ozone exposure in rats. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, USA, 306: 47-57, (2016).

  12. Computers, Electronic Networking and Education: Some American Experiences.

    ERIC Educational Resources Information Center

    McConnell, David

    1991-01-01

    Describes new developments in distributed educational computing at Massachusetts Institute of Technology (MIT, "Athena"), Carnegie Mellon University ("Andrew"), Brown University "Intermedia"), Electronic University Network (California), Western Behavioral Sciences Institute (California), and University of California,…

  13. α-Glucosidase and α-amylase inhibitors from Myrcia spp.: a stronger alternative to acarbose?

    PubMed

    Figueiredo-González, María; Grosso, Clara; Valentão, Patrícia; Andrade, Paula B

    2016-01-25

    "Pedra hume caá" is the common name of five species of Myrcia genus used as traditional medicine for the treatment of diabetes mellitus. In this study, different extracts from Myrcia salicifolia, Myrcia sphaerocarpa, and Myrcia speciosa were investigated for the first time, to identify their phenolic compounds (being 3-O-rhamnoside derivatives of myricetin and quercetin the major ones) and in vitro inhibitory potential against α-glucosidase and α-amylase. These extracts inhibited 90-500 times more α-glucosidase (IC50=0.7 to 4.1 μg ml(-1)) than acarbose and displayed a mild inhibition against α-amylase (IC50=6.1 to 29 μg mL(-1)). Copyright © 2015 Elsevier B.V. All rights reserved.

  14. Spacelab

    NASA Image and Video Library

    1994-03-04

    Space Shuttle Columbia (STS-62) onboard photo of Astronaut Charles (Sam) Gemar talking to ground controllers while assisting astronaut Andrew M. Allen with a soak in the Lower Body Negative Pressure (LBNP) apparatus on the middeck.

  15. 76 FR 40700 - Marine Mammals; File No. 15014-01

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-11

    ... hereby given that Sea World, LLC, 9205 South Park Center Loop, Suite 400, Orlando, FL 32819 [Brad Andrews... Southwest Region, NMFS, 501 West Ocean Blvd., Suite 4200, Long Beach, CA 90802-4213; phone (562) 980-4001...

  16. The (nano) entrepreneur's dilemma

    NASA Astrophysics Data System (ADS)

    Maynard, Andrew D.

    2015-03-01

    Emerging technologies need to be developed responsibly if their benefits are to outweigh any potential risks. Yet do entrepreneurs really have the luxury of grappling with future consequences from the get-go, asks Andrew D. Maynard.

  17. Proposal Writing.

    ERIC Educational Resources Information Center

    Grant, Andrew; And Others

    1988-01-01

    The basics of effective proposal writing, from content to structure to length, are presented in three articles: "Knowledge Is Power" (Andrew Grant, Emily S. Berkowitz), "Write on the Money" (Lucy Knight); and "The Problem Proposal." (MLW)

  18. Early Geologic Education in California--Berkeley and Stanford Show the Way.

    ERIC Educational Resources Information Center

    Norris, Robert M.

    1981-01-01

    Traces the early history of geological education in California universities, with emphasis upon programs at Berkeley and Stanford. Among the pioneers in the field were Joseph LeConte, Andrew C. Lawson, and John C. Branner. (WB)

  19. Goddard Queen Visit

    NASA Image and Video Library

    2007-05-07

    Prince Philip greets astronauts from STS-125 L to R Andrew J Feustel, Michael T Goode, K. Megan McArthur, Michael J. Massimino, Gregory C. Johnson, and Commander Scott D. Altman. Photo Credit: (NASA/Chris Gunn)

  20. 76 FR 28421 - Proposed Information Collection; Comment Request; Marine Recreational Fisheries Statistics Survey

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-17

    ... DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration Proposed Information Collection; Comment Request; Marine Recreational Fisheries Statistics Survey AGENCY: National Oceanic and... Andrews, NOAA, National Marine Fisheries Service, Fisheries Statistics Division, Phone: (301) 713-2328 or...

  1. Annual Report to the Nation on the Status of Cancer, 1975-2014, Featuring Survival

    MedlinePlus

    ... PubMed Google Scholar Angela Mariotto Andrew J Lake Information Management Services, Inc., Rockville, MD Search for other works ... Daniel Miller, Joe Zou, and Steve Scoppa of Information Management Services, Inc., for assistance in compiling the data ...

  2. 14 CFR Appendix D to Part 91 - Airports/Locations: Special Operating Restrictions

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... (Tampa International Airport) Washington, DC (Ronald Reagan Washington National Airport and Andrews Air... Francisco, CA (San Francisco International Airport) Washington, DC (Ronald Reagan Washington National... (Seattle-Tacoma International Airport) Tampa, FL (Tampa International Airport) Washington, DC (Ronald...

  3. 14 CFR Appendix D to Part 91 - Airports/Locations: Special Operating Restrictions

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... (Tampa International Airport) Washington, DC (Ronald Reagan Washington National Airport and Andrews Air... Francisco, CA (San Francisco International Airport) Washington, DC (Ronald Reagan Washington National... (Seattle-Tacoma International Airport) Tampa, FL (Tampa International Airport) Washington, DC (Ronald...

  4. UNDERSTANDING PATHWAYS OF TOXICITY: MAKING SENSE OF CHANGING SIGNALS

    EPA Science Inventory

    Title:
    Understanding Pathways of Toxicity: Making sense of changing signals
    Authors & affiliations:
    Sid Hunter, Maria Blanton, Edward Karoly, Ellen Rogers, Leonard Mole, Phillip Hartig, James Andrews. Reproductive Toxicology Division, National Health and Environmental Ef...

  5. Could we 3D print an artificial mind?

    NASA Astrophysics Data System (ADS)

    Maynard, Andrew D.

    2014-12-01

    3D printing is allowing more complex three-dimensional structures to be manufactured than ever before. Could the convergence between this technology and nanotechnology eventually usher in a new era of artificial intelligence, asks Andrew D. Maynard.

  6. Genetics Home Reference: congenital fibrosis of the extraocular muscles

    MedlinePlus

    ... Nguyen K, Forzano O, Boccaccio I, Delague V, De Sandre-Giovannoli A, Pouget J, Depétris D, Mattei ... Andrews C, Chan WM, McKeown CA, Magli A, de Berardinis T, Loewenstein A, Lazar M, O'Keefe ...

  7. 76 FR 54530 - Qualification of Drivers; Exemption Applications; Vision

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-01

    ... renewable two-year period. They are the following: Daniel F. Albers John A. Bridges Eddie M. Brown Edwin L.... Johnson Terry R. Jones Randall H. Keil James J. Mitchell Andrew M. Nurnberg Kenneth R. Pedersen Joshua R...

  8. Saved by Bell

    NASA Astrophysics Data System (ADS)

    Gisin, Nicolas

    2017-01-01

    In John Stewart Bell and Twentieth-Century Physics: Vision and Integrity, fellow physicist Andrew Whitaker tells the story of Bell's life and his revolutionary discovery that not everything in physics can be explained using only local variables.

  9. Substrate inhibition kinetics of phenol biodegradation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Goudar, C.T.; Ganji, S.H.; Pujar, B.G.

    Phenol biodegradation was studied in batch experiments using an acclimated inoculum and initial phenol concentrations ranging from 0.1 to 1.3 g/L. Phenol depletion an associated microbial growth were monitored over time to provide information that was used to estimate the kinetics of phenol biodegradation. Phenol inhibited biodegradation at high concentrations, and a generalized substrate inhibition model based on statistical thermodynamics was used to describe the dynamics of microbial growth in phenol. For experimental data obtained in this study, the generalized substrate inhibition model reduced to a form that is analogous to the Andrews equation, and the biokinetic parameters {micro}{sub max},more » maximum specific growth; K{sub s}, saturation constant; and K{sub i}, inhibition constant were estimated as 0.251 h{sup {minus}1}, 0.011 g/L, and 0.348 g/L, respectively, using a nonlinear least squares technique. Given the wide variability in substrate inhibition models used to describe phenol biodegradation, an attempt was made to justify selection of particular model based on theoretical considerations. Phenol biodegradation data from nine previously published studies were used in the generalized substrate inhibition model to determine the appropriate form of the substrate inhibition model. In all nine cases, the generalized substrate inhibition model reduced to a form analogous to the Andrews equation suggesting the suitability of the Andrews equation to describe phenol biodegradation data.« less

  10. Gas Analysis and Control Methods for Thermal Batteries

    DTIC Science & Technology

    2013-09-01

    THERMAL BATTERIES (PDFS) INC DOUG BRISCOE JEFFREY REINIG 3 ENERSYS ADVANCED SYSTEMS (PDFS) PAUL SCHISSELBAUER ANDREW SEIDEL TIM...MGMT ATTN RDRL CIO LL TECHL LIB 3 SANDIA NATIONAL LABORATORIES (PDFS) DANIEL WESOLOWSKI EDWARD PIEKOS ANNE GRILLET 2 ADVANCED

  11. STS-125 Food Tasting

    NASA Image and Video Library

    2008-01-24

    JSC2008-E-006897 (24 Jan. 2008) --- Astronauts Scott D. Altman (left), STS-125 commander, and Andrew J. Feustel, mission specialist, participate in a food tasting session in the Flight Projects Division Laboratory at the Johnson Space Center.

  12. Astronauts Allen and Gemar during extravehicular activity (EVA) training in CCT

    NASA Technical Reports Server (NTRS)

    1994-01-01

    Astronauts Charles D. (Sam) Gemar, and Andrew M. Allen participate in a training exercise at JSC's Crew Compartment Trainer (CCT), located in the Space Vehicle Mockup Facility. Gemar sits inside the airlock as Allen reviews procedures for EVA.

  13. 18. Photocopy of photograph (original in the Langley Research Center ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. Photocopy of photograph (original in the Langley Research Center Archives, Hampton, VA LaRC) (LAL 5169) AERIAL VIEW OF THE SEAPLANE TOWING CHANNEL STRUCTURE. - NASA Langley Research Center, Seaplane Towing Channel, 108 Andrews Street, Hampton, Hampton, VA

  14. 76 FR 31295 - Nectarines and Peaches Grown in California; Notice of Withdrawal

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-31

    ... forms to collect information related to the Federal marketing orders for nectarines and peaches grown in... FURTHER INFORMATION CONTACT: Andrew Hatch, Supervisory Marketing Specialist, Marketing Order... Email: [email protected] . SUPPLEMENTARY INFORMATION: Marketing Order Nos. 916 and 917...

  15. Learning from the past

    NASA Astrophysics Data System (ADS)

    Maynard, Andrew D.

    2015-06-01

    When it comes to safety, the jury's still out on which nanoparticle characteristics we should be measuring. But, as Andrew D. Maynard explains, there's a rich history dating back over a hundred years on how we measure them.

  16. Advanced Materials and Solids Analysis Research Core (AMSARC)

    EPA Science Inventory

    The Advanced Materials and Solids Analysis Research Core (AMSARC), centered at the U.S. Environmental Protection Agency's (EPA) Andrew W. Breidenbach Environmental Research Center in Cincinnati, Ohio, is the foundation for the Agency's solids and surfaces analysis capabilities. ...

  17. DEVELOPMENTAL TOXICITY OF DI- AND TETRACHLOROETHANE AND DICHLOROPROPANE IN EMBRYO CULTURE

    EPA Science Inventory

    DEVELOPMENTAL TOXICITY OF DI- AND TETRACHLOROETHANE AND DICHLOROPROPANE IN EMBRYO CULTURE. JE Andrews, H Nichols, and ES Hunter. Reproductive Toxicology Division, NHEERL, USEPA, RTP, NC.

    Disinfection of drinking water with chlorine results in numerous chlorinated byprodu...

  18. 76 FR 1592 - National Poultry Improvement Plan; General Conference Committee Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-11

    ...] National Poultry Improvement Plan; General Conference Committee Meeting AGENCY: Animal and Plant Health... General Conference Committee of the National Poultry Improvement Plan. DATES: The General Conference.... FOR FURTHER INFORMATION CONTACT: Mr. Andrew R. Rhorer, Senior Coordinator, National Poultry...

  19. Mass inflation followed by Belinskii-Khalatnikov-Lifshitz collapse inside accreting, rotating black holes

    NASA Astrophysics Data System (ADS)

    Hamilton, Andrew J. S.

    2017-10-01

    Numerical evidence is presented that the Poisson-Israel mass inflation instability at the inner horizon of an accreting, rotating black hole is generically followed by Belinskii-Khalatnikov-Lifshitz oscillatory collapse to a spacelike singularity. The computation involves following all 6 degrees of freedom of the gravitational field. To simplify the problem, the computation takes as initial conditions the conformally separable solutions of Andrew J. S. Hamilton and Gavin Polhemus [Interior structure of rotating black holes. I. Concise derivation, Phys. Rev. D 84, 124055 (2011), 10.1103/PhysRevD.84.124055] and Andrew J. S. Hamilton [Interior structure of rotating black holes. II. Uncharged black holes, Phys. Rev. D 84, 124056 (2011), 10.1103/PhysRevD.84.124056] just above the inner horizon of a slowly accreting, rotating black hole and integrates the equations inward along single latitudes.

  20. KENNEDY SPACE CENTER, FLA. - STS-114 Mission Specialist Andrew Thomas (right) shows some of the mission equipment to other crew members (from left) Wendy Lawrence, mission specialist; Eileen Collins, commander; and Charles Camarda, mission specialist. Crew members are at KSC for equipment familiarization. STS-114 is classified as Logistics Flight 1 to the International Space Station, delivering new supplies and replacing one of the orbital outpost’s Control Moment Gyroscopes (CMGs). STS-114 will also carry a Raffaello Multi-Purpose Logistics Module and the External Stowage Platform-2. The crew is slated to conduct at least three spacewalks: They will demonstrate repair techniques of the Shuttle’s Thermal Protection System, replace the failed CMG with one delivered by the Shuttle, and install the External Stowage Platform.

    NASA Image and Video Library

    2004-01-27

    KENNEDY SPACE CENTER, FLA. - STS-114 Mission Specialist Andrew Thomas (right) shows some of the mission equipment to other crew members (from left) Wendy Lawrence, mission specialist; Eileen Collins, commander; and Charles Camarda, mission specialist. Crew members are at KSC for equipment familiarization. STS-114 is classified as Logistics Flight 1 to the International Space Station, delivering new supplies and replacing one of the orbital outpost’s Control Moment Gyroscopes (CMGs). STS-114 will also carry a Raffaello Multi-Purpose Logistics Module and the External Stowage Platform-2. The crew is slated to conduct at least three spacewalks: They will demonstrate repair techniques of the Shuttle’s Thermal Protection System, replace the failed CMG with one delivered by the Shuttle, and install the External Stowage Platform.