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1

Postoperative Delirium  

Microsoft Academic Search

This article reviews the incidence, pathophysiological hypotheses, and etiology of postoperative delirium, especially in the elderly. Preoperative, intraoperative, and postoperative risk factors for delirium following surgery are discussed. Results of various studies on postoperative delirium appear hardly comparable due to methodological and population differences. Therefore, it is difficult to draw any conclusions on postoperative delirium in general. Special attention is

Rose C. van der Mast

1999-01-01

2

[Postoperative spine].  

PubMed

Approximately 15-30?% of surgical procedures involving the lumbar spine are associated with complications that require further diagnostic work-up. The choice of imaging modality for postoperative complications depends on the extent, pattern and temporal evolution of the postoperative neurological signs and symptoms as well as on the preoperative clinical status, the surgical procedure itself and the underlying pathology. The interpretation of imaging findings, in particular the distinction between postoperative complications and normally expected nonspecific postoperative imaging alterations can be challenging and requires the integration of clinical neurological information and the results of laboratory tests. The combination of different imaging techniques might help in cases of equivocal imaging results. PMID:25398572

Schlaeger, R; Lieb, J M; Shariat, K; Ahlhelm, F J

2014-11-01

3

[Postoperative pulmonary thromboembolism].  

PubMed

Since 1986, American College of Chest Physicians (ACCP) has been regularly releasing guidelines for antithrombotic therapy for prevention and treatment of thrombosis. The sixth ACCP consensus 2001 conference has recommended successful prevention strategies in surgical patients. A few Japanese prospective studies disclosed that the incidence of deep vein thrombosis(DVT) after general surgery in Japan is about half in western countries. On the other hand, it is reported that the incidence of DVT after total hip replacement and total knee replacement in Japan is almost as same as in western countries. Since there is still little data available for the incidence of postoperative DVT and pulmonary thromboembolism in Japan, it is necessary to organize some prospective multicenter surveys for them. PMID:14577293

Seo, Norimasa

2003-10-01

4

Postoperative pulmonary complications updating.  

PubMed

Postoperative pulmonary complications (PPCs) are a major contributor to the overall risk of surgery. PPCs affect the length of hospital stay and are associated with a higher in-hospital mortality. PPCs are even the leading cause of death either in cardiothoracic surgery but also in non-cardiothoracic surgery. Thus, reliable PPCs risk stratification tools are the key issue of clinical decision making in the perioperative period. When the risk is clearly identified related to the patient according the ARISCAT score and/or the type of surgery (mainly thoracic and abdominal), low-cost preemptive interventions improve outcomes and new strategies can be developed to prevent this risk. The EuSOS, PERISCOPE and IMPROVE studies demonstrated this care optimization by risk identification first, then risk stratification and new care (multifaceted) strategies implementation allowing a decrease in PPCs mortality by optimizing the clinical path of the patient and the care resources. PMID:25168300

Langeron, O; Carreira, S; le Saché, F; Raux, M

2014-01-01

5

Postoperative nausea and vomiting  

PubMed Central

Postoperative nausea and vomiting (PONV) is a long-standing issue, not a new concept in anesthesiology. Despite many studies over the last several decades, PONV remains a significant problem due to its complex mechanism. This review presents a summary of the mechanism underlying the pathogenesis of PONV, focusing on preventive treatment, particularly the use of new drugs. In addition, we discuss the latest meta-analysis results regarding correct clinical use of classic drugs. I also summarize the latest trends of postdischarge nausea and vomiting and the pharmacogenetics, which is attracting a great deal of attention from other medical fields in PONV-related studies. Finally, we discuss the drawbacks of existing studies on PONV and suggest a focus for future investigations. PMID:25302092

2014-01-01

6

Postoperative delirium and plasma melatonin  

Microsoft Academic Search

The molecular mechanisms of postoperative delirium are not understood in detail yet. This condition is similar to cases of mental symptoms in interferon therapy or hemodialysis. We propose that postoperative delirium is caused by a deficiency of serotonin, an important neurotransmitter, and review the evidence supporting our hypothesis. The serotonin deficiency results from a decrease in tryptophan, the serotonin precursor,

K. Uchida; T. Aoki; B. Ishizuka

1999-01-01

7

Postoperative thrombotic thrombocytopenic purpura.  

PubMed

Thrombotic thrombocytopenic purpura (TTP) is a rare, life-threatening disease characterized by acute episodes of thrombocytopenia and microangiopathic hemolytic anemia occurring due to platelet and von Willebrand factor deposition and hyaline thrombi formation in arterioles and capillaries throughout the body, which results in organ ischemia. TTP can be idiopathic or secondary, and there are several causes of secondary TTP. There is a clinical syndrome resembling TTP that occurs after surgical procedures, so-called "postoperative TTP" (pTTP). In this review, the differential diagnosis, pathogenesis and clinical and laboratory features of pTTP, together with the treatment modalities and outcomes of the patients, are discussed. The pTTP is a diagnosis of exclusion, and disseminated intravascular coagulation, heparin-induced thrombocytopenia and medication-induced effects should be ruled out. As in classical TTP, patients with pTTP should be diagnosed and treated with therapeutic plasma exchange (TPE) as early as possible to reduce their morbidity and mortality. Although rarely seen, surgeons and physicians of all specialties should be alert to the possibility of pTTP, and since pTTP is a life-threatening event that usually can be treated successfully with TPE, especially when diagnosed early in its course, it is critical to recognize and treat pTTP promptly. PMID:24374368

Eskazan, Ahmet Emre; Buyuktas, Deram; Soysal, Teoman

2015-01-01

8

JAMA Patient Page: Postoperative Infections  

MedlinePLUS

... longer hospital stays, and increased health care costs. Postoperative infections may cause severe problems, including failure of the surgical procedure, other surgical complications, sepsis, organ failure, and even death. Some persons ...

9

Grid und Cloud Computing.  

E-print Network

??In dieser Arbeit werden die theoretischen Konzepte und mögliche praktische Anwendungsmöglichkeiten von Grid- und Cloud-Computing dargestellt. Als erster Teil der Arbeit wird zuerst auf Grids… (more)

Shahi Barogh, Bahareh

2010-01-01

10

Postoperative Instructions Following Facial Surgery  

E-print Network

Postoperative Instructions Following Facial Surgery 1. Your surgery will be performed in the Surgery Center on the 4th floor of the Center for Health and Healing (CHH) at Oregon Health & Sciences University. The procedure is done under anesthesia administered by an anesthesiologist. After surgery, you

Chapman, Michael S.

11

Postoperative Care of the Facial Laceration  

PubMed Central

The purpose of this investigation is to examine factors involved in the postoperative care of traumatic lacerations. An evidence-based comprehensive literature review was conducted. There are a limited number of scientifically proven studies that guide surgeons and emergency room physicians on postoperative care. Randomized controlled trials must be conducted to further standardize the postoperative protocol for simple facial lacerations. PMID:22132257

Medel, Nicholas; Panchal, Neeraj; Ellis, Edward

2010-01-01

12

US of the Postoperative Penis  

Microsoft Academic Search

A variety of surgical procedures has been developed to manage different penile pathologies and malformations. Penile surgery\\u000a produces anatomical and vascular changes that can be successfully investigated with grey scale and color Doppler ultrasonography.\\u000a In particular, early and late surgical complications can be identified, and postoperative changes of the normal ultrasound\\u000a appearance of the penile envelopes, of the penile bodies

Michele Bertolotto; Paola Martingano; Andrea Spadacci; Maria Assunta Cova

13

Postoperative pain assessment after septorhinoplasty.  

PubMed

Postoperative pain after septorhinoplasty and its optimal management has not been described in detail. Fifty-two adult septorhinoplasty patients were included in a prospective cohort single center study. Patients' and surgical characteristics were evaluated. Outcome and process parameters were analyzed using the questionnaires of the German-wide project Quality Improvement in Postoperative Pain Management (QUIPS) on the first postoperative day. Pain during the first operative day after septorhinoplasty was moderate. Pain management predominately consisted of remifentanil intraoperatively, metamizole in the recovery room, in combination with piritramide in one-third of the patients, and metamizole on ward. Patients younger than 31 years were less satisfied with pain management (P = 0.018). Open rhinoplasty was associated with less satisfaction with pain management (P = 0.007). Use of rib grafts led to more mobility, breathing, sleeping and mood disturbances (P = 0.003, 0.047; 0.047; 0.022, respectively). Preoperative pain counseling was followed by higher satisfaction, less breathing and mood disturbances after surgery (P = 0.021; 0.004; 0.046, respectively). Opioids in the recovery room in addition to non-opioids and treatment with non-opioids on ward led to less maximal pain (P = 0.027 and 0.040, respectively). We conclude that QUIPS is an easy tool to evaluate the quality of postoperative pain management following rhinoplasty. Preoperative pain counseling, specific care for patients with rib grafts, consequent use of opioids in the recovery room in addition to non-opioids, and use of non-opioids on ward seem to be effective to improve pain management after septorhinoplasty. PMID:22130915

Wittekindt, D; Wittekindt, C; Schneider, G; Meissner, W; Guntinas-Lichius, O

2012-06-01

14

Einführung und Überblick  

Microsoft Academic Search

\\u000a Strategisches Controlling und die als Kemaufgabe enthaltene langfristige Unternehmensplanung erarbeitet heute MaBnahmen, die\\u000a die zukunftige Existenz des Untemehmens sicherstellen.1 Dies bedingt eine systematische Erkennung von Chancen und Risiken unter Berucksichtigung von Umweltveranderungen, Damit besteht\\u000a eine Zielsetzung des strategischen Controlling in der Bereitstellung und Nutzung von quantitativen und qualitativen Instrumenten\\u000a zur Frtiherkennung und Frtihwamung, urn existenzbedrohliche Entwicklungen durch eine rechtzeitige Anpassung

Frank Schöneborn

15

Systemische Neurowissenschaften und Psychoseforschung3 Molekulare Psychiatrie und Demenzen3  

E-print Network

Systemische Neurowissenschaften und Psychoseforschung3 Molekulare Psychiatrie und Demenzen3 Forensische Psychiatrie und Psychotherapie3 Neuropsychologie und Psychopathologie3 Schizophrenie3 Angsterkrankungen3 Suchtmedizin3 Systems Neuroscience and Major Psychoses3 Molecular Psychiatry and Dementias3

Gollisch, Tim

16

Postoperative radiotherapy for endometrial cancer  

PubMed Central

Purpose To investigate the prognostic factors and effectiveness of postoperative radiotherapy alone for endometrial carcinoma. Materials and Methods Sixty four patients with stage I-III endometrial cancer (EC) treated with postoperative radiotherapy alone between January 1989 and December 2008 at the Keimyung University Dongsan Medical Center were chosen for the present study. Typically, total hysterectomy, salpingo-oophorectomy and lymphadenectomy were performed on the patient's pelvis. Total dose from 50.4 Gy to 63 Gy was irradiated at pelvis or extended field. Thirteen patients were treated with Co-60 or Ir-192 intracavitary radiotherapy. Follow-up periods were from 7 to 270 months, with a median of 56 months. Results Five year overall survival (OS) rate was 58.7%, respectively. Five year disease-free survival (DFS) rate was 59.2%, respectively. In univariate analysis for OS and DFS, stage, menopausal age, type of operation, serosal invasion, and lymph node involvement were found to be statistically significant. Histologic type was marginally significant. In multivariate analysis for OS and DFS, stage, types of operation, histologic type were also found to be statistically significant. Treatment failure occurred in 14 patients. The main pattern of failure was found to be distant metastasis. Time to distant metastasis was from 3 to 86 months (median, 12 months). There were no grade 3 or 4 complications. Conclusion Stage, types of operation, and histologic type could be the predictive prognostic factors in patients. We contemplated postoperative radiation as effective and safe treatment method for EC. Additional treatment would be needed to reduce distant metastasis. PMID:23170289

Choi, Eun Cheol; Kim, Ok Bae; Byun, Sang Jun; Park, Seung Gyu; Kwon, Sang Hoon

2012-01-01

17

[Postoperative delirium among older people].  

PubMed

Delirium (acute confusional state) is a common and disabling complication among surgical older people. It is often underdiagnosed and undertreated. Its incidence varies by type of intervention and it is associated with several complications such as functional impairment, cognitive dysfunction, prolonged hospitalization and institutionalization. These increase hospitalization costs and the risk of death. There are precipitating and predisposing risk factors, which increase the susceptibility for postoperative delirium. This condition should be considered as a syndrome of epidemiological importance, which needs to be prevented or treated in a timely manner through a multidisciplinary intervention. The perioperative care of elderly patients involves different medical specialties and is a subject of general knowledge. PMID:25117039

Vega P, Eduardo; Nazar J, Claudio; Rattalino F, Marcos; Pedemonte T, Juan; Carrasco G, Marcela

2014-04-01

18

Information und Kommunikation  

NASA Astrophysics Data System (ADS)

Wissen ist mittlerweile unverzichtbar für den entscheidenden Vorsprung auf dem Markt. Unabhängig davon, ob sich das Wissen in Innovationen, neuen Produkten und Dienstleistungen oder in der Verbesserung interner Unternehmensprozesse manifestiert: Wissen ist Treiber von Innovation, Wissen bringt Schnelligkeit und Wissen ist die Voraussetzung für Problemlösungen [40]. Wissensmanagement ist daher der Schlüssel für Unternehmenserfolg und bezeichnet den "bewussten und systematischen Umgang mit der Ressource Wissen und den zielgerichteten Einsatz von Wissen in der Organisation“ [6]. In dieser umfassenden Sichtweise ist Wissensmanagement ein Begriff, der Konzepte, Strategien und Methoden umfasst.

Wesoly, Michael; Ohlhausen, Peter; Bucher, Michael; Hichert, Rolf; Korge, Gabriele; Schnabel, Ulrich; Gairola, Arun; Reichwald, Ralf; Habicht, Hagen; Möslein, Kathrin; Schwarz, Torsten; Schönsleben, Paul; Scherer, Eric; Schloske, Alexander; Adlbrecht, Gerald; Federhen, Jens

19

Prevention of postoperative peritoneal adhesions.  

PubMed

Adhesions are bands of tissue that connect organs together. It is frequently reported after surgery and remains a major problem for health and society. Efforts to prevent or reduce peritoneal adhesions mostly have been unsuccessful, hindered by their empirical basis, lack of good predictive animal models and complexity of adhesion pathogenesis. Although a good surgical technique is a crucial part of adhesion prevention, the technique alone cannot effectively eliminate the adhesions. Thus, there remains a room for further research. A comprehensive literature review of published experimental and clinical studies of adhesion prevention was carried out at the University of Bristol electronic library (MetaLib) with cross-search of seven different medical databases (AMED-Allied and Complementary Medicine Database, BIOSIS Previews on Web of Knowledge, Cochrane Library, Embase and Medline on Web of Knowledge, OvidSP and PubMed) by using key words (peritoneal adhesions, postoperative adhesions, prevention) to explore the progress in different surgical strategies and adjuvant materials used to prevent adhesions formation and reformation. By the end of the study, recommendations formulated for surgeons to be followed during the operations to prevent, as much as possible, the postoperative adhesions. PMID:20382467

Kamel, Remah M

2010-06-01

20

Postoperative ileus: strategies for reduction  

PubMed Central

Postoperative Ileus (POI) is a frequent, frustrating occurrence for patients and surgeons after abdominal surgery. Despite significant research investigating how to reduce this multi-factorial phenomenon, a single strategy has not been shown to reduce POI’s significant effects on length of stay (LOS) and hospital costs. Perhaps the most significant cause of POI is the use of narcotics for analgesia. Strategies that target inflammation and pain reduction such as NSAID use, epidural analgesia, and laparoscopic techniques will reduce POI but are accompanied by a simultaneous reduction in opioid use. Pharmacologic means of stimulating gut motility have not shown a positive effect, and the routine use of nasogastric tubes only increases morbidity. Recent multi-site phase III trials with alvimopan, a peripherally acting mu-antagonist, have shown significant reductions in POI and LOS by 12 and 16 hours, respectively, by blunting the effects of narcotics on gut motility while sparing centrally mediated analgesia. Use of alvimopan, along with a multi-modal postoperative treatment plan involving early ambulation, feeding, and avoiding nasogastric tubes, will likely be the crux of POI treatment and prevention. PMID:19209273

Lubawski, James; Saclarides, Theodore

2008-01-01

21

Transgene Pflanzen und Pflanzenbiotechnologie  

Microsoft Academic Search

\\u000a Schon seit Tausenden von Jahren versucht der Mensch, Nutzpflanzen und Nutztiere durch selektive Züchtung zu verbessern. Dies\\u000a erfolgt überwiegend nach dem Prinzip von Versuch und Irrtum. Im Laufe der Zeit haben die Tier- und Pflanzenzüchter gelernt,\\u000a dass die Verbesserung ihrer Nutztiere und -pflanzen eine biologische Grundlage hat. Schließlich experimentierte schon der\\u000a Begründer der Genetik, Gregor Mendel, mit Erbsen. Er erforschte

David P. Clark; Nanette J. Pazdernik

22

Postoperative pain management - predictors, barriers and outcome.  

E-print Network

??Despite the availability of clinical practice guidelines, effective analgesics and new technologies for drug administration, the management of postoperative pain continues to remain problematic and… (more)

Wickström Ene, Kerstin

2008-01-01

23

Magnetic resonance imaging of the postoperative spine.  

PubMed

Magnetic resonance (MR) imaging is an excellent technique for evaluating the postoperative spine when the patient has chronic or recurrent symptoms. Potential causes of pain following lumbar surgery include arachnoiditis, stenosis, epidural fibrosis and disc herniations, pseudomeningocele, and infection. The postoperative cervical spine may be complicated by hematoma, canal or foraminal stenosis, disc herniation, and cord abnormality. This article reviews standard imaging protocols, the normal postoperative appearance of the spine, and the characteristic imaging findings for each of the abnormal postoperative conditions. PMID:11371319

Ross, J S

2000-01-01

24

Mensaspeiseplan und aktuelle Infos  

E-print Network

/Zucker, Schmalz Zubereitung: Die Kartoffeln schälen, durchdrücken und in eine Schüssel geben. Eigelb und Zucker in Schmalz beidseitig goldgelb backen. Auf einem Küchenkrepp abtropfen und in Zimt-Zucker wenden. Dazu

Fiebig, Peter

25

Knie- und Sprunggelenk  

Microsoft Academic Search

Arthrodesen am Sprung- und Kniegelenk haben trotz Fortschritten in der Endoprothetik weiterhin ihr Indikationsspektrum. Sie erleben sogar durch die steigenden Fallzahlen der Endoprothetik und den damit auch gehäuft auftretenden Komplikationen eine Renaissance. Wesentliche Prinzipien einer Arthrodese sind die Aneinanderlagerung gut durchbluteter Knochenflächen, die stabile Fixation und die Kompression. Gegenüber internen Osteosyntheseverfahren weisen externe gewisse Nachteile auf. Exemplarisch sind die höhere

T. Mückley; M. Diefenbeck; M. Goebel; V. Bühren; G. O. Hofmann

2005-01-01

26

Postoperative Mycobacterium abscessus nodular conjunctivitis.  

PubMed

Non-tuberculous or 'atypical' mycobacteria are unusual causes of ocular or periocular infection. We report a case of postoperative Mycobacterium abscessus infection of the conjunctiva. A 71-year-old gentleman developed nodular conjunctival injection and irritation 6 weeks after cataract surgery. After failure of topical therapy with antibiotics, steroids and lubricants, a biopsy was taken. Histological examination revealed non-caseating granulomas within which were clusters of acid-fast bacilli, subsequently identified as M. abscessus. The patient received a total of 16 weeks of oral antimycobacterial treatment and the conjunctivitis completely resolved. A suspected recurrence was successfully treated with topical ciprofloxacin and at final follow up 15 months later there was no evidence of infection. To the best of our knowledge this is the first report of non-tuberculous mycobacterial infection of the conjunctiva occurring after cataract surgery. PMID:18700926

Merani, Rohan; Orekondy, Sid; Gottlieb, Thomas; Janarthanan, Perumal; McCarthy, Stanley; Karim, Rooshdiya; Booth, Frances

2008-05-01

27

[Intramedullary glioma. Postoperative MRI aspects].  

PubMed

MRI is the standard exploration of intramedullary tumours. Following up the patients is of prime importance to detect and treat possible recurrences at an early stage. The purpose of this paper is to specify the postoperative MRI semiology of intraspinal gliomas. During the 1986-1992 period, 47 patients operated upon in the Bicêtre hospital for primary intraspinal tumours were followed up with high-field MR (1.5 Tesla, Signa, G.E.). The retrospective visual study was carried out by two neuro-radiologists. The patients' group consisted of 24 women and 23 men aged from 15 to 67 years (mean 38 years). The tumours treated were 29 ependymomas and 18 astrocytomas. Eighty-five MRI examinations were analysed. Most of them comprised at least two planes in T1 and T2-weighted spin echo sequences with gadolinium injection, then only T1-weighted spin echo sequences after gadolinium injection (0.1 mmol/kg). The mean postoperative follow up period in the 47 patients was 32 months (range 7 to 84 months). Contrast enhancement of the spinal cord was observed in 20 cases. In the 6 patients with recurrence (5 astrocytomas, 1 malignant ependymoma) there was a segmental increase of spinal cord volume with contrast enhancement after gadolinium injection. In 3 out of these 6 patients clinical deterioration appeared later than MRI semiology. In clinically stable patients neither enhancement nor increase in spinal cord size was found in 27 cases, and enhancement alone was noted in 12 cases. There was no reliable criterion in the analysis of post gadolinium signal enhancement that could be used to differentiate recurrence from cicatricial contrast enhancement.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:7629570

Borocco, A; Idir, A; Joubert, E; Lacroix, C; Hurth, M; Doyon, D

1995-06-01

28

POSTOPERATIVE COGNITIVE IMPAIRMENT AND POSTOPERATIVE DELIRIUM: RISK FACTORS, PATHOPHYSIOLOGY AND MANAGEMENT  

Microsoft Academic Search

Postoperative cognitive impairment and postoperative delirium: risk factors, pathophysiology and management Soilemezi E, Konstantinidis P, Georgiadou Th. A significant number of patients exhibit impairment in cognitive function immediately following surgery or later; the impact of this postoperative cognitive dysfunction on the recovery and quality of life of the patient but also on the necessity for supportive and rehabilitation care is

Konstantinidis A. Panagiotis; Georgiadou Theodora

2007-01-01

29

Postoperative Chemoradiotherapy for Extrahepatic Bile Duct Cancer  

Microsoft Academic Search

Purpose: To evaluate the effect of postoperative concurrent chemoradiotherapy using three-dimensional conformal radiotherapy and to identify the prognostic factors that influence survival in patients with extrahepatic bile duct cancer. Methods and Materials: We retrospectively analyzed the data from 101 patients with extrahepatic bile duct cancer who had undergone postoperative concurrent chemoradiotherapy using three-dimensional conformal radiotherapy. Of the 101 patients, 52

Jin-hong Park; Eun Kyung Choi; Seung Do Ahn; Sang-wook Lee; Si Yeol Song; Sang Min Yoon; Young Seok Kim; Yu Sun Lee; Sung-Gyu Lee; Shin Hwang; Young-Joo Lee; Kwang-Min Park; Tae Won Kim; Heung Moon Chang; Jae-Lyun Lee; Jong Hoon Kim

2011-01-01

30

Postoperative surgical complications of lymphadenohysterocolpectomy  

PubMed Central

Rationale The current standard surgical treatment for the cervix and uterine cancer is the radical hysterectomy (lymphadenohysterocolpectomy). This has the risk of intraoperative accidents and postoperative associated morbidity. Objective The purpose of this article is the evaluation and quantification of the associated complications in comparison to the postoperative morbidity which resulted after different types of radical hysterectomy. Methods and results Patients were divided according to the type of surgery performed as follows: for cervical cancer – group A- 37 classic radical hysterectomies Class III Piver - Rutledge -Smith ( PRS ), group B -208 modified radical hysterectomies Class II PRS and for uterine cancer- group C -79 extended hysterectomies with pelvic lymphadenectomy from which 17 patients with paraaortic lymphnode biopsy . All patients performed preoperative radiotherapy and 88 of them associated radiosensitization. Discussion Early complications were intra-abdominal bleeding ( 2.7% Class III PRS vs 0.48% Class II PRS), supra-aponeurotic hematoma ( 5.4% III vs 2.4% II) , dynamic ileus (2.7% III vs 0.96% II) and uro - genital fistulas (5.4% III vs 0.96% II).The late complications were the bladder dysfunction (21.6% III vs 16.35% II) , lower limb lymphedema (13.5% III vs 11.5% II), urethral strictures (10.8% III vs 4.8% II) , incisional hernias ( 8.1% III vs 7.2% II), persistent pelvic pain (18.91% III vs 7.7% II), bowel obstruction (5.4% III vs 1.4% II) and deterioration of sexual function (83.3% III vs 53.8% II). PRS class II radical hysterectomy is associated with fewer complications than PRS class III radical hysterectomy , except for the complications of lymphadenectomy . A new method that might reduce these complications is a selective lymphadenectomy represented by sentinel node biopsy . In conclusion PRS class II radical hysterectomy associated with neoadjuvant radiotherapy is a therapeutic option for the incipient stages of cervical cancer. Abbreviations: PRS- Piver Rutledge-Smith, II- class II, III- class III PMID:24653760

Marin, F; Ple?ca, M; Bordea, CI; Voinea, SC; Burl?nescu, I; Ichim, E; Jianu, CG; Nicol?escu, RR; Teodosie, MP; Maher, K; Blidaru, A

2014-01-01

31

Struktur und Dynamik in flüssigem Germanium und Silizium-Germanium.  

E-print Network

??In der vorliegenden Arbeit wird Struktur und Dynamik in flüssigem Germanium und Silizium-Germanium aus experimenteller Sicht behandelt. Die Arbeit gliedert sich folgendermaßen. Im ersten Kapitel… (more)

Weis, Henning Peter

2012-01-01

32

REVIEW ARTICLE Anaesthetics and postoperative cognitive dysfunction: a  

E-print Network

REVIEW ARTICLE Anaesthetics and postoperative cognitive dysfunction: a pathological mechanism Research Centre, Manesar, Gurgaon, India Summary With longevity, postoperative cognitive decline postoperative cognitive dysfunction. The aim of this review is to highlight the clinical aspects

Mandal, Pravat K.

33

Gedankenexperimente über Quantenmechanik und Gravitation.  

E-print Network

??In dieser Arbeit sollen Gedankenexperimente über Quantenmechanik und Gravitation formuliert und analysiert werden. Wir wollen untersuchen welche Möglichkeiten im Rahmen eines Gedankenexperimentes bestehen mehr über… (more)

Krizek, Gerd Christian

2008-01-01

34

Predicting and preventing postoperative decline in older cardiac surgery patients.  

E-print Network

??Introduction: Delirium, depression, pressure ulcers and infection are frequently occurring postoperative complications in older cardiac surgery patients. Prevention of postoperative complications in cardiac surgery is… (more)

Ettema, R.G.A.

2014-01-01

35

Personalentwicklung und Arbeitnehmer  

Microsoft Academic Search

\\u000a Betriebe und Unternehmen unterliegen in Zeiten dynamischer Entwicklungen an nationalen und internationalen Märkten einem erheblichen\\u000a Veränderungsdruck. Die Sicherstellung von Innovations- und Anpassungsfähigkeit im Konkurrenzwettbewerb zählt daher zu den\\u000a zentralen Aufgaben einer strategischen Unternehmensplanung, in der die Personalpolitik eine wichtige Funktion übernimmt. Unter dem Begriff des Human Ressource Management (HRM) hat sich die betriebliche Personalpolitik in ihren Inhalten, Methoden, Instrumenten wie

Rolf Dobischat; Karl Düsseldorff

36

Personalentwicklung und Arbeitnehmer  

Microsoft Academic Search

Betriebe und Unternehmen unterliegen in Zeiten dynamischer Entwicklungen an nationalen und internationalen Märkten einem erheblichen\\u000a Veränderungsdruck. Die Sicherstellung von Innovations- und Anpassungsfähigkeit im Konkurrenzwettbewerb zählt daher zu den\\u000a zentralen Aufgaben einer strategischen Unternehmensplanung, in der die Personalpolitik eine wichtige Funktion übernimmt. Unter dem Begriff des Human Ressource Management (HRM ) hat sich die betriebliche Personalpolitik in ihren Inhalten, Methoden, Instrumenten

Rolf Dobischat; Karl Düsseldorff

37

Chemie und Umwelt  

Microsoft Academic Search

\\u000a „Seitdem Menschen existieren, verändern sie ihre Umwelt. Doch erst in der hoch industrialisierten Gesellschaft und mit der\\u000a raschen Zunahme der Erdbevölkerung in unserem (20.) Jahrhundert haben Eingriffe in den Naturhaushalt nach Art und Umfang eine\\u000a Größenordnung erreicht, die zu einer emsten und weltweiten Gefahr für die Natur, aber auch für den Menschen selbst geführt\\u000a haben.

Dirk Flottmann; Detlev Forst; Helmut Roßwag

38

Informationstechnologie, Governance und Compliance  

Microsoft Academic Search

Zusammenfassung  In dem Beitrag werden die Ergebnisse einer Web-Recherche zu den Themen Governance und Compliance in Zusammenhang mit dem Einsatz\\u000a von Informationstechnologie vorgestellt. Hierbei zeigt sich, dass die Informationstechnologie eine doppelte Rolle einnimmt.\\u000a Sie tritt zum einen als Instrument zur Realisierung der betrieblichen Governance und Compliance in Erscheinung. Zum anderen\\u000a ist die IT auch ein wesentlicher Gegenstand von Governance und Compliance,

Alexander Teubner; Tom Feller

2008-01-01

39

Licht und Farbe  

Microsoft Academic Search

\\u000a „Wozu soll das denn gut sein?!“ Auf den ersten Blick hielt sich die Begeisterung der Rasselsteiner Beschäftigten in Grenzen,\\u000a als sie erfuhren, dass Anlagen, Produktionshallen und Außenfassaden des neuen Werkteils in Andernach in leuchtend blauen und\\u000a grünen Farbabstufungen gestaltet werden sollten. Je weiter die Hallen jedoch innen und außen wuchsen, desto deutlicher war\\u000a ein Meinungsumschwung spürbar. Inzwischen greifen Mitarbeiter in

Bernd Hoffmann

40

[Systemic multimodality postoperative analgesia in vascular surgery].  

PubMed

The study comprised a total of fifty-three patients after endured operations performed on the infrarenal portion of the aorta and large vessels of the lower extremities. The work was aimed at evaluating quality of postoperative analgesia in various regimens of multimodality analgesia based on non-narcotic analgesics. The following combinations of the drugs were used: ketoprofen + tramadol; lornoxicam + tramadol; paracetamol + tramadol; paracetamol + lornoxicam + tramadol. The use in the postoperative period of the above mentioned regimens of multimodality analgesics makes it/nmpfble to achieve a good analgesic effect without administration of narcotic analgesics. The inclusion of paracetamol into the postoperative multimodality analgesia results in a rapid onset of an analgesic effect and decreased requirements in prescribing tramadol. In patients running a high risk of an ulcerogenic effect of non-steroidal anti-inflammatory drugs, postoperative analgesia should be carried out based on paracetamol and tramadol whose combination appears to provide a beneficial analgesic effect. PMID:22616238

Kazennov, V V; Shishkin, M N; Amerov, D B

2011-01-01

41

Metzger und Mord.  

E-print Network

??Die vorliegende Arbeit behandelt die zwischen 2007 und 2013 publizierten Metzger-Krimis von Thomas Raab, wobei eine gattungstheoretische Einordnung der Texte sowie die erzähltheoretische Analyse der… (more)

Rouha, Andrea

2014-01-01

42

Post-operative hyponatraemia in orthopaedic injury  

Microsoft Academic Search

Post-operative hyponatraemia can be dangerous and can go unrecognised as the presenting signs and symptoms are often confused with post-operative or post-anaesthesia sequelae. Infusion of dextrose containing fluids in the peri-operative period is a well-documented cause of this electrolyte imbalance.We conducted a retrospective study to identify the incidence of hyponatraemia following surgery for orthopaedic injury. Medical notes and fluid charts

A. A. Tambe; R. Hill; P. J. Livesley

2003-01-01

43

Attention to postoperative pain control in children  

PubMed Central

Even with the rapid development of pediatric postoperative pain management, pediatric patients have remained undertreated for postoperative pain because of difficulty in pain assessment and concerns regarding side effects of opioid analgesics. Although there are no perfect pain assessment techniques and no absolutely safe analgesics, proper monitoring and an individualized analgesic plan after due consideration of age, operative procedures, and underlying illness, using multimodal analgesics may improve the quality of pain control in children. PMID:24729838

Lee, Ji Yeon

2014-01-01

44

Freud und Wittgenstein im Konflikt zwischen skularem Denken und Religion  

E-print Network

, den 25. Februar 2015, 18.15h-19.30h / Hauptgebäude / Raum 120 ,,Sigmund Freuds Atheismus wurde zumFreud und Wittgenstein im Konflikt zwischen säkularem Denken und Religion Symposion mit dem, säkularem Denken und Religion entfaltet hat. Er zeigt, wie Freud in seinem Leben und Denken auf sehr

Sola, Rolf Haenni

45

Amphiphile und Makromoleküle: Phasenverhalten hybrider Mizellen.  

E-print Network

??In dieser Arbeit wurde mit Röntgenkleinwinkelstreuung (SAXS) und Fluoreszenzkorrelationsspektroskopie (FCS) die Struktur und das Phasenverhalten supramolekularer Komplexe aus Lipiden und hydrophiler DNA in unpolarem Lösungsmittel… (more)

Hohner, Andreas

2005-01-01

46

Diagnostik und Therapie der Spondylodiszitis  

Microsoft Academic Search

Zusammenfassung Die Inzidenz der Spondylitis\\/Spondylodiszitis nimmt aufgrund multifaktorieller Ursachen zu. Frühstadien ohne Lähmungssymptomatik und ohne wesentliche Instabilität können konservativ mit Ruhigstellung und testgerechter Antibiotikatherapie erfolgreich behandelt werden. Neu aufgetretene neurologische Ausfälle, septische Verläufe, ausgedehnte knöcherne Destruktionen, Abszessbildungen, Instabilitäten, Fehlstellungen und eine drohende Querschnittsymptomatik stellen Grenzen der konservativen Therapie dar. Ziele der operativen Therapie sind die Resektion des Infektherds und die

T. Mückley; A. Kemmer; G. O. Hofmann

2004-01-01

47

13. und 14. Universitt  

E-print Network

13. und 14. November 2008 Otto-von- Guericke- Universität www.math.tu-berlin.de/~felsner/DMSWo Der. Termin: 13. und 14. November 2008 Ort: Otto-von-Guericke-Universit¨at Magdeburg. Es gibt vier Kurse zu Arbeit das Erlernte an ¨Ubungsproblemen anzuwenden. Die einzelnen Kurse werden von Universit

Henk, Martin

48

Beckenring- und Azetabulumverletzungen  

Microsoft Academic Search

Zusammenfassung  Für die definitive Versorgung von Beckenringverletzungen und Azetabulumfrakturen sind meist ausgedehnte operative Zugänge erforderlich. Sie gehen mit einer umfangreichen Exposition der frakturierten Knochen und einem ausgeprägten zusätzlichen operativen Weichteiltrauma einher. Alternativen zu diesen extrem exponierenden Zugängen wären wünschenswert. Der Einsatz computergesteuerter navigierter Operationsverfahren zur gedeckten Einbringung von Schrauben ist mit einer Reihe von Vorteilen verbunden. Wie eigene Ergebnisse zeigten, ist

G. O. Hofmann; I. Marintschev; T. Mückley; F. Mendler

2007-01-01

49

Serum cholesterol levels and postoperative atrial fibrillation  

PubMed Central

Background Post-operative atrial fibrillation is an important complication after coronary bypass surgery. As inflammation and oxidative stress were makedly encountered in the etiology, high cholesterol was also defined to provoke atrial fibrillation. In this present study, the relationship between postoperative atrial fibrillation and preoperative serum lipid levels were evaluated. Methods A total of 100 patients, who were operated at the department of Cardiovascular Surgery of our hospital were included to the study analysis. Patients, who had preoperative atrial fibrillation, thyroid dysfunction, or left atrial dilatation (above 4.5 cm) were excluded from the study. Patients were divided into two groups with postoperative atrial fibrillation development (Group I n?=?36), and without atrial fibrillation development (Group II n?=?64). Preoperative routine blood analyses, ECG, echocardiography were evaluated. Patients were followed for atrial fibrillation development for one month starting from the intensive care unit at the postoperative period. Serum lipid profiles and thyroid function were measured. For homogenization of inflammatory factors and oxidative stress, treatments other than statins, betablockers, calcium channel blockers, aspirin, ACE inhibitors, and ARB were stopped for 10 days. Atrial fibrillation for at least ?5 minutes in the intensive care unit was accepted as postoperative atrial fibrillation. Results Demographic data were similiar between groups (p?>?0.05). There was no difference in TC levels between groups, whereas LDL-C levels were statistically lower in patients developing post-operative atrial fibrillation (106.67?±?28.36 vs 118.75?±?27.75; P?postoperative atrial fibrillation development. High levels of LDL-C in the preoperative period could be predictor of atrial fibrillation development in the post operative period. PMID:24712763

2014-01-01

50

Postoperative Delirium: The Importance of Pain and Pain Management  

Microsoft Academic Search

Postoperative delirium is common in geriatric patients. Few studies have examined events in the postoperative period that may contribute to the occurrence of postoper- ativedelirium.Wehypothesizedthatpostoperativedelir- iumisrelatedtopostoperativepainand\\/orpainmanage- ment strategy. Patients aged 65 years who were scheduled for major noncardiac surgery were studied. A structured interview was conducted preoperatively and for the first 3 postoperative days to determine the pres- ence of

Linnea E. Vaurio; Laura P. Sands; Yun Wang; E Ann Mullen; Jacqueline M. Leung

2006-01-01

51

Controlling postoperative ileus by vagal activation.  

PubMed

Postoperative ileus is a frequently occurring surgical complication, leading to increased morbidity and hospital stay. Abdominal surgical interventions are known to result in a protracted cessation of bowel movement. Activation of inhibitory neural pathways by nociceptive stimuli leads to an inhibition of propulsive activity, which resolves shortly after closure of the abdomen. The subsequent formation of an inflammatory infiltrate in the muscular layers of the intestine results in a more prolonged phase of ileus. Over the last decade, clinical strategies focusing on reduction of surgical stress and promoting postoperative recovery have improved the course of postoperative ileus. Additionally, recent experimental evidence implicated antiinflammatory interventions, such as vagal stimulation, as potential targets to treat postoperative ileus and reduce the period of intestinal hypomotility. Activation of nicotinic receptors on inflammatory cells by vagal input attenuates inflammation and promotes gastrointestinal motility in experimental models of ileus. A novel physiological intervention to activate this neuroimmune pathway is enteral administration of lipid-rich nutrition. Perioperative administration of lipid-rich nutrition reduced manipulation-induced local inflammation of the intestine and accelerated recovery of bowel movement. The application of safe and easy to use antiinflammatory interventions, together with the current multimodal approach, could reduce postoperative ileus to an absolute minimum and shorten hospital stay. PMID:20379998

Lubbers, Tim; Buurman, Wim; Luyer, Misha

2010-04-14

52

VLAP: results immediately post-op  

NASA Astrophysics Data System (ADS)

Visual laser ablation of the prostate (VLAP) has been shown to be as effective with fewer complications than TURP in the treatment of bladder outlet obstruction secondary to benign prostatic hyperplasia. Questions have been raised about VLAP regarding prolonged irritative and obstructive voiding symptoms postoperatively. It is postulated that these symptoms are due to the slow slough of necrotic debris following VLAP. In an effort to improve upon the technique of VLAP, patients underwent lasing of the prostate in the routine manner (2, 4, 8, and 10 o'clock positions with sixty watts for sixty seconds) using Nd:YAG free beam energy. A bladder neck incision was then performed using a contact laser fiber. International prostate symptom score assessments were done preoperatively; one week and six weeks postoperatively. Post void residual urine volumes and prostate size were also evaluated. The findings indicate that symptom scores and post void residual urine volumes have significantly improved within ten days postoperatively using this technique.

Cowles, Robert S.

1996-05-01

53

Postoperative Pain Trajectories in Cardiac Surgery Patients  

PubMed Central

Poorly controlled postoperative pain is a longstanding and costly problem in medicine. The purposes of this study were to characterize the acute pain trajectories over the first four postoperative days in 83 cardiac surgery patients with a mixed effects model of linear growth to determine whether statistically significant individual differences exist in these pain trajectories, and to compare the quality of measurement by trajectory with conventional pain measurement practices. The data conformed to a linear model that provided slope (rate of change) as a basis for comparing patients. Slopes varied significantly across patients, indicating that the direction and rate of change in pain during the first four days of recovery from surgery differed systematically across individuals. Of the 83 patients, 24 had decreasing pain after surgery, 24 had increasing pain, and the remaining 35 had approximately constant levels of pain over the four postoperative days. PMID:22448322

Chapman, C. Richard; Zaslansky, Ruth; Donaldson, Gary W.; Shinfeld, Amihay

2012-01-01

54

Gabapentin in Acute Postoperative Pain Management  

PubMed Central

Gabapentin (1-aminomethyl-cyclohexaneacetic acid) is an amino acid that has the structure of the neurotransmitter ?-aminobutyric acid (GABA). It is a novel drug used for the treatment of postoperative pain with antihyperalgesic properties and a unique mechanism of action. Gabapentin and the related, more potent compound pregabalin have been shown to be beneficial in the treatment of neuropathic pain as well as postoperative pain following spinal surgery and hysterectomy. This study reviews five aspects of gabapentin: (1) chemical and structural characteristics; (2) pharmacokinetics and pharmacodynamics; (3) application in acute pain management; (4) adverse effects; and (5) drug safety. Overall, gabapentin has been reported to be a safe and efficacious drug for the treatment of postoperative pain. PMID:24829909

Chang, Connie Y.; Challa, Chaitanya K.; Shah, Janki; Eloy, Jean Daniel

2014-01-01

55

Postoperative spine imaging in cancer patients.  

PubMed

Primary or metastatic spine tumors can present with pain and/or neurologic compromise depending on their location within the spinal axis. Metastases and multiple myeloma comprise most of these lesions. Management of spinal tumors includes surgical decompression with stabilization (neo), adjuvant chemotherapy and radiation therapy, curettage, bone grafting, bone marrow replacement, and palliative treatment with vertebral augmentation. Pre- and postoperative imaging plays a critical role in the diagnosis and management of patients with spinal tumors. This article reviews postoperative imaging of the spine, including imaging protocols, immediate and long-term routine imaging findings, and emergent findings in symptomatic patients. PMID:24792611

Coronel, Esther E; Lien, Ruby J; Ortiz, A Orlando

2014-05-01

56

Post-operative delirium in elderly patients  

PubMed Central

Delirium is a common, but an often underdiagnosed complication in the elderly following major surgery. Recognising delirium in early stages and diagnosing the condition based on established criteria can improve the outcome and management. Managing delirium with environmental, supportive and pharmacological interventions will possibly reduce the incidence and side-effects associated with post-operative delirium. The purpose of this article is to provide an over view of the current knowledge about the disease, diagnosis, pathogenesis, preventive strategies, and treatment of post-operative delirium. PMID:25024465

Vijayakumar, B; Elango, P; Ganessan, R

2014-01-01

57

Management of postoperative complications: general approach.  

PubMed

The goal of postoperative management is to promote early mobility and avoid postoperative complications, recognizing the potentially devastating impact of complications on elderly patients with hip fracture. The recommended approach involves early mobilization; freedom from tethers (indwelling urinary catheters and other devices); effective pain control; treating malnutrition; preventing pressure ulcers; reducing risk for pulmonary, urinary, and wound infections; and managing cognition. This carefully structured and patient-centered management provides older, vulnerable patients their best chance of returning to their previous level of functioning as quickly and safety as possible. PMID:24721365

Sanguineti, V Ana; Wild, Jason R; Fain, Mindy J

2014-05-01

58

A prospective cohort study on the effectiveness of 3500 IU versus 5000 IU bemiparin in the prophylaxis of postoperative thrombotic events in obese patients undergoing orthopedic surgery  

Microsoft Academic Search

\\u000a Zusammenfassung  HINTERGRUND: Postoperative Thrombosen zählen zu den meist gefürchteten Komplikationen der Orthopädie, die lebensbedrohliche\\u000a Konsequenzen nach sonst höchst erfolgreichen Operationen wie Knie- oder Hüftersatz nach sich ziehen können. Körpergewicht\\u000a ist einer der wichtigsten Risikofaktoren für Thrombosen und wird in der Prophylaxe zur Dosierung herangezogen. Seit der Einführung\\u000a dieser Schemata haben orthopädische Populationen jedoch stark an Gewicht gewonnen. Diese Studie untersucht ob

Patrick Vavken; Andreas Lunzer; Josef Georg Grohs

2009-01-01

59

Functional postoperative treatment of Achilles tendon repair  

Microsoft Academic Search

Twenty-one patients with surgically repaired Achilles tendon tears that were treated postoperatively with a functional orthosis rather than routine cast immobiliza tion were evaluated. The orthosis allowed unrestricted plantar flexion and limited dorsiflexion to neutral. Toe- touch weightbearing crutch ambulation was allowed immediately and was gradually increased over the 6 to 8 weeks of treatment. Of the 21 patients, 14

Thomas R. Carter; Peter J. Fowler; Cathy Blokker

1992-01-01

60

Selective Dorsal Rhizotomy and Postoperative Pain Management  

Microsoft Academic Search

Background: Selective dorsal rhizotomy (SDR) is an operation method that decreases the degree of spasticity with long-lasting beneficial effects for children with spastic diplegia. Children undergoing SDR are postoperatively in severe pain, a pain related to both the extensive surgical exposure with multilevel laminectomy and the nerve root manipulation. Various pain management strategies for children undergoing SDR have been published.

K. Hesselgard; P. Reinstrup; L. G. Stromblad; J. Undén; B. Romner

2007-01-01

61

Influences of Gender on Postoperative Morphine Consumption  

PubMed Central

Background: Gender related differences on morphine consumption during postoperative period following abdominal surgeries. Materials and Methods: Four hundred and fifty ASA I & II patients of either sex (male =231, female = 219), between the age group of 18-65 y undergoing elective intra abdominal surgeries under general anaesthesia were included for the study. Patients with preexisting pain either acute or chronic preoperatively were excluded from the study. Anaesthesia and analgesia protocol during surgery was standardized. Postoperatively, a loading dose was given to achieve the visual analogue scale (VAS) of ?30 and subjects were connected to patient control analgesia (PCA) pump containing 0.4 mg/ml of morphine configured to deliver a bolus dose (1 mg) with a 5 min lock-out period. The total analgesic requirements along with VAS (visual analog scale) score were analysed between males and females in the first 24 h postoperatively. All demographic data and between group comparisons were analysed with student t-test. Within group comparisons were done by using one-way-ANOVA test and Tukey’s Honestly significant Difference test. Results: During the first 24 h, males consumed significantly higher amount of morphine (34.35 ± 6.68 mg) when compared to females (26.78 ± 7.14 mg), p < 0.001. Conclusion: We conclude that men require more morphine in the postoperative period than women.

Poovathai, Raja; Pondiyadanar, Srinivasan

2014-01-01

62

Preoperative risk factors for postoperative delirium  

Microsoft Academic Search

The objective of this article was to estimate the incidence of delirium in a sample of patients undergoing elective surgery and to identify the preoperative factors most closely associated with developing this complication. Consecutive patients (n=500) underwent a full preoperative medical evaluation including assessment of cognitive and functional status. Daily evaluation on postoperative days 1 through 4 included medical record

David Litaker; Joseph Locala; Kathleen Franco; David L. Bronson; Ziad Tannous

2001-01-01

63

Postoperative delirium: the tryptophan dyregulation model  

Microsoft Academic Search

A model previously presented by Uchida in this journal [Med. Hypotheses 53 (1997) 103] described a mechanism for postoperative delirium. It described an increased level of melatonin resulting in a central “serotonin shortage”. This construct adequately explained only the hypoactive type of delirium. Recently it has been shown that a reduction in urinary metabolites of melatonin is associated with hyperactive

Michael C Lewis; Sheila R Barnett

2004-01-01

64

Postoperative Hydrocephalus in Cranial Base Surgery  

PubMed Central

The incidence of postoperative hydrocephalus and factors relating to it were analyzed in 257 patients undergoing cranial base surgery for tumor resection. A total of 21 (8%) patients developed postoperative hydrocephalus, and all required shunting, Forty-two (17%) patients developed cerebrospinal fluid (CSF) leak that required placement of external drainage systems (ventriculostomy or lumbar drain, or both); 10 (23%) of these 42 patients eventually needed shunt placement to stop the leak because of hydrocephalus. Prior craniotomy, prior radiation therapy, and postoperative CSF infection were also associated with an increased risk of developing hydrocephalus (48% versus 6%, 19% versus 8%, and 14% versus 7%, respectively). Prior radiation and postoperative CSF infection increased the risk of CSF leak in patients with hydrocephalus (30% versus 18% and 30% versus 9%, respectively). CSF leak and hydrocephalus commonly occurred in patients who underwent resection of a glomus tumor. In conclusion, 8% of patients who underwent cranial base surgery for tumors developed de novo hydrocephalus; half of them also had CSF leak in addition to hydrocephalus; and all required shunt placement for CSF diversion. PMID:17171147

Duong, Duc H.; O'Malley, Sean; Sekhar, Laligam N.; Wright, Donald G.

2000-01-01

65

Aktuelle Probleme und Anforderungen  

Microsoft Academic Search

\\u000a Mit dem Softwareprodukt SAP Strategic Enterprise Management\\/Business Analytics (SAP SEM\\/BA) hat SAP neue Software-Lösungen\\u000a für die strategische sowie operative Unternehmensplanung und Entscheidungsunterstützung auf den Markt gebracht.

Marco Meier; Werner Sinzig; Peter Mertens

66

Volkszählung und Mikrozensus1  

NASA Astrophysics Data System (ADS)

Die Volkszählung (Zensus) ist seit langem weltweit eine statistische Erhebung über Bevölkerung und Erwerbstätigkeit. In vielen Ländern wird sie heute in etwa 10jährigem Abstand durchgeführt. In Deutschland wurde sie in den 80er Jahren zum Politikum. Datenschutzängste, verbunden mit politischen Vorgängen (Friedensbewegung), erregten die Menschen, und das Bundesverfassungsgericht steckte neue Grenzen ab. Nach kontroversen Auseinandersetzungen, an denen die Deutsche Statistische Gesellschaft (DStatG) konstruktiv beteiligt war, kam es zur Volkszählung 1987. Den nachfolgenden Paradigmenwechsel hin zu einem registergestützten Zensus 2011 hat die DStatG ebenfalls kreativ mitgestaltet. Im Beitrag wird dieser Weg nachgezeichnet. Das neue Konzept wird vorgestellt und kritisch gewürdigt. Betroffen war auch der Mikrozensus als größte Bevölkerungs- und Arbeitsmarktstichprobe zwischen den Zensen. Nicht zuletzt durch das Wirken eines wissenschaftlichen Beirats, dessen Mitglieder von der DStatG vorgeschlagen wurden, blieb diese Erhebung in ihrem Kern für die Zukunft erhalten.

Grohmann, Heinz

67

Stressentstehung und Stressreaktion  

Microsoft Academic Search

\\u000a Das lateinische Verb »stringere« heißt zusammendrücken, zusammenziehen. Der Begriff »Stress« kommt in seiner heutigen Bedeutung\\u000a aus dem Englischen und bedeutete ursprünglich das Testen von Metallen oder Glas auf ihre Belastbarkeit. Der Biochemiker Hans\\u000a Selye (1907– 1982) übertrug den Begriff Stress in die Psychologie und Medizin. Ausgangspunkt waren endokrinologische Untersuchungen.\\u000a Selye stellte fest, dass bei starken Umweltbelastungen wie zum Beispiel Hitze

Sven Max Litzcke; Horst Schuh

68

Hüftprothesenerhalt mit lokaler chirurgischer Revision und Anlage einer Fistula persistens  

Microsoft Academic Search

Zusammenfassung\\u000a Hintergrund  Die Zahl der j?hrlich implantierten Endoprothesen steigt kontinuierlich. Gleichzeitig werden die Patienten immer ?lter. Somit\\u000a werden auch die von postoperativen Komplikationen Betroffenen immer ?lter und auch kr?nker. Die postoperative periprothetische\\u000a Infektion stellt die schwerwiegendste dieser Komplikationen dar. Die Behandlungsstrategien von Endoprotheseninfektionen werden\\u000a kontrovers diskutiert. Empirische Untersuchungen zeigen, dass zur Zeit der Prothesenwechsel (ein- bis mehrzeitig) das Verfahren\\u000a mit den

A. H. Tiemann; L. Homagk; M. Diefenbeck; T. Mückley; G. O. Hofmann

2007-01-01

69

Seminar Methoden der Mustererkennung und Klassifikation Grundlagen der Wahrscheinlichkeitsrechnung und  

E-print Network

. Jahrhunderts zur¨uck und sind eng mit den Namen der Mathematiker Blaise Pascal und Pierre de Fermat verbunden besch¨aftigte sich mit diesem Problem und teilte in einem Brief Fermat seine L¨osung mit. Ein Entsprechendes tat Fermat. Schlie�lich gab auch Christian Hyugens ein Ergebnis an. Diese Gelehrten sahen schon

Briesemeister, Linda

70

Typen von Planungs- und Kontrollsystemen  

Microsoft Academic Search

\\u000a Die in diesem zweiten Band beschriebenen Anwendungssysteme haben die Aufgabe, Entscheidungsträgern Informationen und Entscheidungsvorschläge\\u000a zu präsentieren, die ihnen bei der Unternehmensplanung und -kontrolle helfen. Wir bezeichnen sie daher als Planungs- und Kontrollsysteme (PuK-Systeme). Die hierzu benötigten Daten stammen zum großen Teil aus den operativen Systemen bzw. den Administrations-\\u000a und Dispositionssystemen, die in Band 1 dargestellt sind. Immer mehr werden aber

Peter Mertens; Marco C. Meier

71

Intravenous Ketoprofen in Postoperative Pain Treatment after Major Abdominal Surgery  

Microsoft Academic Search

In recent years considerable attention has been paid to the treatment of postoperative pain, with regard to the favorable effect of adequate analgesia on patient outcome. Multimodal analgesia (e.g., opioids and nonsteroidal anti-inflammatory drugs [NSAIDs] or local anesthetics) is recommended for effective postoperative pain relief. There are few data on the use of NSAIDs in postoperative pain treatment after abdominal

Dagmar Oberhofer; Jasna Skok; Visnja Nesek-Adam

2005-01-01

72

Prospective Trial of Aggressive Postoperative Bowel Stimulation Following Radical Hysterectomy  

Microsoft Academic Search

Introduction. Postoperative traditional feeding protocols are not based on scientific studies, but rather on anecdotal evidence. We present the first prospective trial of aggressive postoperative bowel stimulation following radical hysterectomy in an attempt to determine its effect on the length of hospital stay.Methods. Twenty consecutive patients undergoing radical hysterectomy were entered onto a prospective trial of aggressive postoperative bowel stimulation,

James Fanning; Sandia Yu-Brekke

1999-01-01

73

Haltungsstörungen, Scheuermannsche Krankheit und Schularzt  

Microsoft Academic Search

Zusammenfassung Haltungsstörungen und Scheuermannsche Krankheit sind bei unserer Jugend deutlich häufiger geworden. Es wird die Ansicht vertreten, daß die Zunahme eine Akzelerationstolge ist. Das überstürzte Körper- und Wirbelsäulenwachstum (Pubertätswachstumsschub) spielt eine ausschlaggebende Rolle in der Genese. Wahrscheinlich spielen auch exogene Noxen, vor allem die Bewegungsarmut unserer Schüler, eine Rolle. Prophylaxe: Durch Haltungsturnen können die Haltungsschwäche und der Haltungsverfall beeinflußt werden.

H. Wespi

1969-01-01

74

Wirkstoffe, Medikamente und Mathematische Bildverarbeitung  

NASA Astrophysics Data System (ADS)

Die Entwicklung neuer Medikamente ist langwierig und teuer. Der erste Schritt ist hierbei die Suche nach neuen Wirkstoffkandidaten, die für die Behandlung bislang schwer therapierbarer Krankheiten geeignet sind. Hierfür stehen der Pharma- und Biotechnologieindustrie riesige Substanzbibliotheken zur Verfügung. In diesen Bibliotheken werden die unterschiedlichsten Substanzen gesammelt, die entweder synthetisch hergestellt oder aus Pilzen, Bakterienkulturen und anderen Lebewesen gewonnen werden können.

Bauer, Günter J.; Lorenz, Dirk A.; Maaß, Peter; Preckel, Hartwig; Trede, Dennis

75

Cardiac risk assessment: decreasing postoperative complications.  

PubMed

Preoperative cardiac assessment helps identify patients undergoing noncardiac surgery who are at risk for significant postoperative cardiac complications and those who may benefit from additional preoperative evaluation and perioperative care. Advanced practice nurses can identify surgery- and patient-related risks by conducting a thorough health history and physical examination. Multiple risk indices and evidence-based guidelines are available to inform health care providers regarding patient evaluation and strategies to reduce postoperative cardiac risk. In general, preoperative tests are recommended only if the findings will influence medical therapy or perioperative monitoring or will require postponement of surgery until a cardiac condition can be corrected or stabilized. Medication management is a crucial component of the preoperative assessment; providers may need to initiate the use of beta-blockers and make decisions regarding continuing or withholding antiplatelet and anticoagulant therapy. Preoperative cardiac risk stratification, medication reconciliation, and device management are essential for providing safe care for patients. PMID:25645037

Thanavaro, Joanne L

2015-02-01

76

Postoperative Vision Loss after Reverse Shoulder Arthroplasty  

PubMed Central

We report a case which highlights the rare but devastating complication of postoperative vision loss (POVL) in orthopaedic surgery. Though documented previously, it has not been reported in shoulder arthroplasty surgery of which we present the first case. The aetiology of POVL is difficult to elucidate due to its elusive nature. We explain the risks associated with regional blocks used for such surgery and how this may be related to POVL. We must be vigilant of the possible causes of POVL as curative treatment is often not possible and hence must take preventative measures which we have recommended. Fortunately, the patient fully recovered at 10 months postoperatively with excellent function of her reverse shoulder arthroplasty. PMID:25610682

Scadden, John

2014-01-01

77

Critic appraisal. Postoperative sensitivity with indirect restorations.  

PubMed

Postoperative sensitivity is characterized by short and sharp pain, and often experienced after cementation of indirect restorations. Factors associated with the occurrence of post-cementation sensitivity include type of cement, removal of smear layer by acid-etching, aggressive tooth preparation, inadequate provisional restorations, and patient's age. Its prevention is based on either interfering with mechanoreceptor activity or occluding the dentinal tubules. Regarding the latter, application of dentin desensitizers may be effective for blocking the tubules and significantly reducing dentin permeability and consequently postoperative sensitivity. This Critical Appraisal will present available clinical data where traditional materials such as zinc phosphate and glass ionomer cements (GIC) as well as self-adhesive resin-based cements were used. PMID:24761824

Farias, David; Walter, Ricardo; Swift, Edward J

2014-01-01

78

[Standardised postoperative analgesic system in orthopaedic surgery].  

PubMed

In order to treat patients with postoperative acute pain effectively, we have developed a standardised algorithm for analgesia. This process includes three levels and the appropriate supply of medication. The therapy level is defined based on the scale of the operation. Accordingly, the prescription and handling of the pain medication is simplified for the attending physician and nurses. The pain level has to be measured by the nursing staff sing a visual analogue scale (VAS). Thus, the efficiency of the analgesics will be continuously evaluated and controlled. The standardised supply medication can be applied in those cases with pain levels > or = 4 (VAS). It is possible to up- or down-grade the level within the system depending on the actual pain experienced by the patient. With this structured pain therapy algorithm we now have a guideline for the consistent postoperative analgesic treatment of patients. PMID:16821177

Giesa, M; Drees, P; Meurer, A; Jage, J; Eckardt, A

2006-01-01

79

Enteroscopic treatment of early postoperative small bowelobstruction  

Microsoft Academic Search

  Background: Early postoperative small bowel obstruction (EPSBO) occurs in 1% of patients undergoing laparotomy and has a mortality\\u000a rate exceeding 17%. Nasogastric (NG) decompression is successful in avoiding reoperation in 73% of patients. Repeat laparotomy\\u000a has been recommended when obstruction does not resolve after 14 days of NG decompression. We report four patients with EPSBO\\u000a treated successfully with push enteroscopy

K. S. Gersin; J. L. Ponsky; R. D. Fanelli

2002-01-01

80

Postoperative doppler evaluation of liver transplants.  

PubMed

Doppler ultrasound plays an important role in the postoperative management of hepatic transplantation, by enabling early detection and treatment of various vascular complications. This article describes the normal Doppler findings following liver transplantation and reviews the imaging appearances of various vascular complications associated with it. The article also discusses transient waveform abnormalities, often seen on a post-transplant Doppler examination, and the importance of differentiating them from findings suggestive of ominous vascular complications. PMID:25489129

Sanyal, Rupan; Zarzour, Jessica G; Ganeshan, Dakshina M; Bhargava, Puneet; Lall, Chandana G; Little, Mark D

2014-10-01

81

Postoperative Pain Management: Organisation and Audits  

Microsoft Academic Search

Pain relief after surgical procedures continues to be a major medical challenge. The alleviation of pain is given a high priority\\u000a by the medical profession and health authorities, who recognise that improvements in perioperative analgesia are not only\\u000a desirable for humanitarian reasons, but essential for reducing postoperative morbidity and mortality [1], [2]. The guidelines for acute pain management established by

D. Caristi

82

Postoperative Chemoradiotherapy for Extrahepatic Bile Duct Cancer  

SciTech Connect

Purpose: To evaluate the effect of postoperative concurrent chemoradiotherapy using three-dimensional conformal radiotherapy and to identify the prognostic factors that influence survival in patients with extrahepatic bile duct cancer. Methods and Materials: We retrospectively analyzed the data from 101 patients with extrahepatic bile duct cancer who had undergone postoperative concurrent chemoradiotherapy using three-dimensional conformal radiotherapy. Of the 101 patients, 52 (51%) had undergone complete resection (R0 resection) and 49 (49%) had microscopic or macroscopic residual tumors (R1 or R2 resection). The median radiation dose was 50 Gy. Also, 85 patients (84%) underwent concurrent chemotherapy with 5-fluorouracil. Results: The median follow-up period was 47 months for the surviving patients. The 5-year overall survival rate was 34% for all patients. A comparison between patients with R0 and R1 resection indicated no significant difference in the 5-year overall survival (44% vs. 33%, p = .2779), progression-free survival (35% vs. 22%, p = .3107), or locoregional progression-free survival (75% vs. 63%, p = .2784) rates. An analysis of the first failure site in the 89 patients with R0 or R1 resection indicated isolated locoregional recurrence in 7 patients. Elevated postoperative carbohydrate antigen 19-9 level was an independent prognostic factor for overall survival (p = .001) and progression-free survival (p = .033). A total of 3 patients developed Grade 3 or greater late toxicity. Conclusion: Adjuvant concurrent chemoradiotherapy using three-dimensional conformal radiotherapy appears to improve locoregional control and survival in extrahepatic bile duct cancer patients with R1 resection. The postoperative carbohydrate antigen 19-9 level might be a useful prognostic marker to select patients for more intensified adjuvant therapy.

Park, Jin-hong; Choi, Eun Kyung; Ahn, Seung Do; Lee, Sang-wook; Song, Si Yeol; Yoon, Sang Min; Kim, Young Seok; Lee, Yu Sun [Department of Radiation Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul (Korea, Republic of); Lee, Sung-Gyu; Hwang, Shin; Lee, Young-Joo; Park, Kwang-Min [Department of General Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul (Korea, Republic of); Kim, Tae Won; Chang, Heung Moon; Lee, Jae-Lyun [Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul (Korea, Republic of); Kim, Jong Hoon, E-mail: jhkim2@amc.seoul.k [Department of Radiation Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul (Korea, Republic of)

2011-03-01

83

[QUIPS: quality improvement in postoperative pain management].  

PubMed

Despite the availability of high-quality guidelines and advanced pain management techniques acute postoperative pain management is still far from being satisfactory. The QUIPS (Quality Improvement in Postoperative Pain Management) project aims to improve treatment quality by means of standardised data acquisition, analysis of quality and process indicators, and feedback and benchmarking. During a pilot phase funded by the German Ministry of Health (BMG), a total of 12,389 data sets were collected from six participating hospitals. Outcome improved in four of the six hospitals. Process indicators, such as routine pain documentation, were only poorly correlated with outcomes. To date, more than 130 German hospitals use QUIPS as a routine quality management tool. An EC-funded parallel project disseminates the concept internationally. QUIPS demonstrates that patient-reported outcomes in postoperative pain management can be benchmarked in routine clinical practice. Quality improvement initiatives should use outcome instead of structural and process parameters. The concept is transferable to other fields of medicine. PMID:21767792

Meissner, Winfried

2011-01-01

84

Postoperative wound infection in colorectal surgery.  

PubMed

Postoperative wound infection is one of common problems in a surgical ward. In our surgical department, from 1988 to December 1992, 254 cases were operated on for colorectal diseases. The indications for these operations were as follows; colorectal carcinoma (191 cases), inflammatory bowel diseases (22 cases), diverticulitis (14 cases), and others (27 cases). Of these 254 cases, 119 were males (46.85%) and 135 were females (53.15%), 211 cases (83.1%) were operated on as elective surgery, 43 cases (16.9%) as emergencies. Of these 254 cases, 36 (14.2%) had postoperative wound infection, 25 cases (11.8%) after elective surgery, and 11 cases (25.6%) postemergency operations. Of these 36 cases, 22 cases (61.11%) were males and 14 cases (38.88%) were females. In our study, postoperative wound infection was mostly noted in patients operated on for colorectal carcinoma (27 cases, 14.1%), as compared with 5 cases operated on for diverticulitis (35.7%), 2 cases for I.B.D. (9.1%) and 2 cases for other indications (7.4%). Most of these wound infections were treated with drainage and frequent dressing while 10 cases received antibiotics. PMID:8935193

Bielecki, K; Badi, H; Kami?ski, P; Kubiak, J

1995-01-01

85

Technikwissenschaft - Erfinden und Entdecken  

NASA Astrophysics Data System (ADS)

Umrissen wird das allgemeine Ziel der Technikwissenschaft, konstruktiv zu verwerten und nicht-natürlich Entdeckbares zu erfinden. Wir befinden uns in einer Umwälzung der Technik im Verlauf der wissenschaftlich-technischen Revolution, auf dem Wege zu einem neuen Techniktyp. Dieser schafft und nutzt die künstliche Intelligenz. Dazu benötigt der in der Technik tätige Mensch spezielle Kenntnisse und Erfahrungen in kreativ-konstruktiver, -gestalterischer und erfinderischer Sicht mit dem Einsatz spezieller Strukturen und Sprachen. Vorschläge zur Arbeitsweise in der Technik werden gegeben.Translated AbstractTechnological Science-Invent and DiscoverThe general aim of engineering science is outlined to utilize results constructively and to invent something that cannot be discovered in nature. We are now in a period of transformation of technology in the course of scientific-technological revolution, on the way to a new type of technology. This new type creates and utilizes artificial intelligence. For this, man acitive in this field requires special knowledge and experiences in a creative, constructive, design-oriented and ultimately inventive way by deploying special structures and languages. There are also made some proposals concerning the method of working in the field of technology.

Linnemann, Gerhard

86

Postoperative endophthalmitis: caution is the watchword.  

PubMed

Postoperative endophthalmitis is the most feared complication following cataract surgery. It can be caused by infection entering the eye during surgery or by inadequately cleaned instruments. Sterile phaco handpieces might retain remnants of soft lens matter or visco-elastic which might later contaminate other patients, causing inflammation in their eyes. The costs of an endophthalmitis outbreak are heavy, including poor patient outcomes, temporary theatre closure, rising waiting lists and damage to a hospital's reputation. This article raises awareness of endophthalmitis and provides useful recommendations for ophthalmic theatre personnel. PMID:16729598

Field, Dorothy; Merrick, Edward

2006-01-01

87

Pathology Case Study: Post-operative bleeding  

NSDL National Science Digital Library

This transfusion medicine case study, provided by the University of Pittsburgh Department of Pathology, is an excellent resource for students and instructors in the health science fields. This case involves an 83-year-old woman with post-operative bleeding and anemia. Laboratory values are provided in Table 1. The official final diagnosis is accompanied by a discussion of the contributing doctorâÂÂs findings and a list of references. This is an excellent resource for students in the health sciences to familiarize themselves with using patient history and laboratory results to diagnose patientâÂÂs conditions.

Kiss, Joseph; Puca, Kathleen; Qu, Lirong; Triulzi, Darrell

2008-04-04

88

Bio und Gentechnologie  

Microsoft Academic Search

\\u000a Der Begriff Biotechnologie umfasst eine Vielzahl höchst unterschiedlicher Arbeitsgebiete. Dazu gehören Jahrtausende alte Fermentations-Technologien\\u000a (fermentum, lat. = Sauerteig, Gärung) zur Lebensmittelherstellung aber auch täglich neu publizierte und patentierte Verfahren\\u000a zur Herstellung neuer Biopharmaka mit gentechnologischen Methoden.

Dirk Flottmann; Detlev Forst; Helmut Roßwag

89

Atombau und Elementarteilchen  

Microsoft Academic Search

\\u000a Chemie ist eigentlich nichts anderes als ein Wechselspiel von Elektronen. Fragt man jedoch, mit was sich die Chemie befasst,\\u000a so lautet die Antwort: Mit den Stoffen unserer Umwelt, seien sie nun natürlich oder synthetisch. Urn dies verstehen zu können,\\u000a ist es unerlässlich, sich mit Atombau und Chemischer Bindung zu befassen.

Dirk Flottmann; Detlev Forst; Helmut Roßwag

90

Departement Maschinenbau und Verfahrenstechnik  

E-print Network

. Embrechts D 4 Systemmodellierung 151-0573-00 E. Shafai D 4 Obligatorische Fächer (mindestens 3 von 5) LE-Nr Maschinenbau und Verfahrenstechnik Wählbare Fächer LE-Nr. Dozent Spra- che ECT S HS ECTS FS Computational

Daraio, Chiara

91

Archimedes, und die gestorten  

E-print Network

Archimedes, und die gest¨orten Kreise Vortrag im Naturhistorischen Museum Mainz Prof. Dr. Duco van;Archimedes Gem¨alde von Jusepe de Ribera (1630) (Madrid) #12;Archimedes Gem¨alde von Domenico Fetti (1620-241 #12;· 263: Friedensvertrag mit Rom · Fast f¨unfzig Jahre Frie- den! · Archimedes wird Berater am Hof

van Straten, Duco

92

Postoperative Pain Following Foot and Ankle Surgery: A Prospective Study  

PubMed Central

Background Orthopaedic procedures have been reported to have the highest incidence of pain compared to other types of operations. There are limited studies in the literature that investigate postoperative pain. Materials and Methods A prospective study of 98 patients undergoing orthopedic foot and ankle operations was undertaken to evaluate their pain experience. A Short-Form McGill Pain Questionnaire (SF-MPQ) was administered preoperatively and postoperatively. Results The results showed that patients who experienced pain before the operation anticipated feeling higher pain intensity immediately postoperatively. Patients, on average, experienced higher pain intensity 3 days after the operation than anticipated. The postoperative pain intensity at 3 days was the most severe, while postoperative pain intensity at 6 weeks was the least severe. Age, gender and preoperative diagnosis (acute versus chronic) did not have a significant effect on the severity of pain that patients experienced. Six weeks following the operation, the majority of patients felt no pain. In addition, the severity of preoperative pain was highly predictive of their anticipated postoperative pain and 6-week postoperative pain, and both preoperative pain and anticipated pain predict higher immediate postoperative pain. Conclusion The intensity of patients' preoperative pain was predictive of the anticipated postoperative pain. Patients' preoperative pain and anticipated postoperative pain were independently predictive of the 3-day postoperative pain. The higher pain intensity a patient experienced preoperatively suggested that their postoperative pain severity would be greater. Therefore, surgeons should be aware of these findings when treating postoperative pain after orthopaedic foot and ankle operations. PMID:19026197

Chou, Loretta B.; Wagner, Dominic; Witten, Daniela M.; Martinez-Diaz, Gabriel J.; Brook, Nancy S.; Toussaint, Michele; Carroll, Ian R.

2009-01-01

93

Halbwertzeiten und totale Clearance von Inulin und PAH im Kindesalter  

Microsoft Academic Search

Cleargnceuntersuchungen zur diagnostischen und prognostischen Beurteilung der Nierenfunktion sind in der Erwachsenenmedizin heute zu Routinemagnahmen geworden. Eine ~hnlich breite Anwendung in der Kinderheillcunde ist jedoeh keineswegs zu be\\/iirworten, da einerseits dem Kinde psyehisehe und physisehe Belastungen mSgliehst ersloart werden sollen, zumal wenn sie dutch eine im Einzelfall entbehrliehe MaBnahme verursaeht werden, und da andererseits in den meisten Fgllen die kindliehe

U. Keuth; A. Neumann

1958-01-01

94

Histologic features predicting postoperative Crohn's disease recurrence.  

PubMed

: Recurrence of Crohn's disease (CD) after ileal or colonic resection is common. Many studies have tried to identify predictors of postoperative recurrence (POR) in CD. A wide range of histologic features have been identified, but for most of them, the literature provided conflicting data. In last years, several studies have suggested that histologic findings including inflammatory changes within the enteric nervous system of the resection margin may be associated with CD recurrence. Herein, after briefly summarizing pathophysiology of POR, we review all histological features that have been studied so far: granulomas, histologic appearance at the margin of resection, plexitis, lymphatic vessel density in proximal margin of resection, and morphological analysis of Paneth cells. Granulomas and chronic inflammation at the margin of resection do not seem to predict POR in CD. Active disease at the margin of resection, plexitis, lymphatic vessels density, morphological analysis of Paneth cells may predict POR. Most of these histological features await replication in independent studies. Available evidence indicates that histological findings may be taken into account when developing strategies aimed at preventing postoperative CD recurrence. PMID:25437814

Bressenot, Aude; Peyrin-Biroulet, Laurent

2015-02-01

95

Management of recurrent postoperative fungal endophthalmitis  

PubMed Central

Aim: To report the management of recurrent postoperative fungal endophthalmitis (POFE) after failed pars plana vitrectomy (PPV) and antifungal therapy. Settings and Design: Tertiary Care Referral Centre in North India. Retrospective, single institution, interventional case-series. Materials and Methods: Six patients with microbiologically proven recurrent post-operative fungal endophthalmitis refractory to conventional management were included. The final recurrence was managed with intraocular lens (IOL) explantation and re-PPV. Main outcome measures included preserved globe anatomy, visual acuity and retinal status. ‘Anatomical success’ was defined as preserved anatomy of the globe, and absence of signs of inflammation. ‘Functional success’ was defined as an attached retina and a best corrected visual acuity of better than 20/400. Results: Of the six cases of POFE, five were culture positive [Aspergillus flavus (1), Aspergillus fumigatus (2), Candida albicans (1) and Candida glabrata (1)] and one was smear positive for yeast. All recurred (mean recurrences, 4) despite a mean of 2.17 PPVs and intravitreal amphotericin B. No recurrences were observed after IOL explantation with re – PPV (median follow-up, 37 months). Pre-study defined criteria for successful ‘anatomical’ and ‘functional’ outcomes were achieved in 83.3% and 50% respectively. Conclusion: This report highlights the effective role of combined IOL explantation with PPV in managing recurrent POFE. PMID:24618484

Vinekar, Anand; Dogra, Mangat R; Avadhani, Kavitha; Gupta, Vishali; Gupta, Amod; Chakrabarti, Arunaloke

2014-01-01

96

Postoperative Radiation Therapy for Parotid Mucoepidermoid Carcinoma  

PubMed Central

Salivary gland cancers are rare and represent approximately 5% of all head and neck cancers and only 0.3% of all malignancies. The majority (75%) of salivary gland tumors occur in the parotid gland, and while benign lesions are more common, mucoepidermoid carcinoma (MEC) makes up 40–50% of malignant parotid gland tumors. No randomized controlled trials exist regarding the role of adjuvant radiation for patients who undergo surgical resection of low-grade MECs. Herein, we report two cases of successful postoperative radiation therapy in low-grade, pT2N0 MEC of the parotid gland. The role of adjuvant radiation therapy for patients with MEC of the parotid gland is based on data from institution reviews and lacks data from randomized controlled trials. Per our review of the literature, the pathological findings of positive surgical margins and/or perineural invasion in two patients with low-grade MEC of the parotid gland warranted adjuvant radiation for improved local control after partial parotidectomy. Both patients tolerated postoperative radiation therapy with only mild side effects and, at last follow-up, five years after completion of therapy, had no clinical or radiographic evidence of either local recurrence or distant metastasis. PMID:25580323

Olsen, Meghan P.; Mitchell, Allen O.; Miles, Edward F.

2014-01-01

97

Immediate postoperative complications in transsphenoidal pituitary surgery: A prospective study  

PubMed Central

Background: Considering the important role of pituitary gland in regulating various endocrine axes and its unique anatomical location, various postoperative complications can be anticipated resulting from surgery on pituitary tumors. We examined and categorized the immediate postoperative complications according to various tumor pathologies. Materials and Methods: We carried out a prospective study in 152 consecutive patients and noted various postoperative complications during neurosurgical intensive care unit stay (within 48 hrs of hospital stay) in patients undergoing transsphenoidal removal of pituitary tumors. Results: In our series, various groups showed different postoperative complications out of which, cerebrospinal fluid leak was the commonest followed by diabetes insipidus, postoperative nausea and vomiting, and hematoma at operation site. Conclusion: Various immediate postoperative complications can be anticipated in transsphenoidal pituitary surgery even though, it is considered to be relatively safe. PMID:25191182

Chowdhury, Tumul; Prabhakar, Hemanshu; Bithal, Parmod K.; Schaller, Bernhard; Dash, Hari Hara

2014-01-01

98

Intraperitoneal capsaicin treatment reduces postoperative gastric ileus in awake rats  

Microsoft Academic Search

Introduction: Postoperative gastric ileus interferes with postoperative recovery of the patients. Previous studies suggest that capsaicin-sensitive afferent neurons are involved in the mediation of postoperative gastric ileus. Methods: A group of rats were equipped with a strain gauge transducer sutured to the gastric wall. Gastric motility was recorded after intraperitoneal injection of capsaicin (0.1 µmol\\/kg and 1 µmol\\/kg) or vehicle.

T. T. Zittel; T. Meile; E. C. Jehle; H. D. Becker

2001-01-01

99

Selective visceral angiography in obscure postoperative gastrointestinal bleeding.  

PubMed Central

Postoperative gastrointestinal bleeding may be difficult to diagnose and treat. Selective visceral angiography localised the bleeding site in seven out of ten episodes of obscure postoperative gastrointestinal haemorrhage, and in two cases radiological embolisation was used successfully to control the bleeding. Angiography, preferably during an episode of haemorrhage, is recommended whenever possible for patients with undiagnosed postoperative gastrointestinal bleeding. Images Fig. 1 Fig. 2a Fig. 2b Fig. 3a Fig. 3b PMID:3499838

Ng, B. L.; Thompson, J. N.; Adam, A.; Spencer, J.; Hemingway, A. P.; Blumgart, L. H.; Allison, D. J.

1987-01-01

100

Fehlstellungen und Verkürzungen nach Oberschenkelschaftfrakturen  

Microsoft Academic Search

Zusammenfassung  \\u000a Posttraumatische Fehlstellungen am Oberschenkelschaft treten v.a. nach komplexen Frakturen auf. Die Indikation zur Korrekturosteotomie\\u000a kann bei klinisch relevanten Beinlängendifferenzen, bei kosmetisch entstellenden und biomechanisch wirksamen Rotations- und\\u000a Achsfehlern im Sinn einer präarthrotischen Deformität gestellt werden. Bei Umstellung im Femurschaftbereich hat sich der Verriegelungsmarknagel\\u000a aufgrund der frühen Belastungsfähigkeit und des limitierten Weichteilzugangs als Implantat bewährt. Jeder Korrekturosteotomie\\u000a sollte eine exakte

Thomas Mückley; Gunther Hofmann; Volker Bühren

2002-01-01

101

Preoperative, intraoperative, and postoperative measures to further reduce spinal infections  

PubMed Central

Background: The rate of postoperative spinal infections varies from 0.4% to 3.5%. Although the introduction of additional preoperative, intraoperative, and postoperative methods of prophylaxis should further reduce spinal infection rates, these measures will not succeed unless surgeons are well informed of their availability, utility, and efficacy. This study provides a review of several preoperative, intraoperative, and postoperative methods of prophylaxis that could minimize the risk of postoperative spinal infections. Various preoperative, intraoperative, and postoperative measures could further reduce the risk of spinal infections. Preoperative prophylaxis against methicillin-resistant Staphylococcus aureus could utilize (1) nasal cultures and Bactroban ointment (mupirocin), and (2) multiple prophylactic preoperative applications of chlorhexidine gluconate (CHG) 4% to the skin. Intraoperative prophylactic measures should not only include the routine use of an antibiotic administered within 60 min of the incision, but should also include copious intraoperative irrigation [normal saline (NS) and/or NS with an antibiotic]. Intraoperatively, instrumentation coated with antibiotics, and/or the topical application of antibiotics may further reduce the infection risk. Whether postoperative infections are reduced with the continued use of antibiotic prophylaxis remains controversial. Other postoperative measures may include utilization of a silver (AgNO3)-impregnated dressing (Silverlon dressing) and the continued use of bed baths with CHG 4%. The introduction of multiple preoperative, intraoperative, and postoperative modalities in addition to standardized prophylaxis may further contribute to reducing postoperative spinal infections. PMID:21427784

Epstein, Nancy E.

2011-01-01

102

The role of postoperative radiotherapy in carcinoma of the endometrium.  

PubMed

The role of adjuvant postoperative radiotherapy in endometrial carcinoma after surgery remains controversial. There is a great variation between centres in deciding when to give postoperative external beam radiotherapy and/or vaginal vault brachytherapy for patients with endometrial carcinoma. The role of pelvic and para-aortic lymphadenectomy as well as the need for postoperative radiotherapy after this type of surgical staging continue to be debated. Furthermore, the role of adjuvant chemotherapy either alone or in combination with adjuvant radiotherapy also remains to be determined. This overview discusses the role of postoperative radiotherapy in the context of surgery and other adjuvant treatments in carcinoma of the endometrium. PMID:18455376

Kong, A; Powell, M; Blake, P

2008-08-01

103

Geldmenge, Zinssatz, Bankenverhalten und Zentralbankpolitik  

Microsoft Academic Search

\\u000a Zusammenfassung  Entsprechend der Aufgabenstellung steht die Analyse der Zentralbankpolitik im Mittelpunkt dieser Arbeit. Als Aktionsparameter\\u000a werden die KreditgewÄhrung der Zentralbank an den Staat, die Rediskontkontingente, der Reservesatz sowie die Verzinsung für\\u000a in- und auslÄndische LiquiditÄtsreserven betrachtet und ihr Einflu\\\\ auf Geldmenge, Sollzinssatz, Kreditvolumen und LiquiditÄtsreserven\\u000a untersucht.\\u000a \\u000a Ausgchend von den Bilanzen der Zentralbank und des Kreditbanken-systems wird zunÄchst in einem vereinfachten Gleichgewichtsmodell

Hans-Joachim Jarchow; Peter Rühmann; Günther Engel

1970-01-01

104

IT-Services und ASP.  

E-print Network

??PRINTAUSGABE: 1 CD enthalten!  – Gegenstand der hier vorgestellten Magisterarbeit sind das Design und die Erstellung eines Service-Katalogs für einen Application Service Provider (ASPs). ASPs… (more)

Lindenthaler, Bernd

2008-01-01

105

Single dose dipyrone for acute postoperative pain  

PubMed Central

Background Dipyrone (metamizole) is a non-steroidal anti-inflammatory drug used in some countries to treat pain (postoperative, colic, cancer, and migraine); it is banned in others because of an association with life-threatening blood agranulocytosis. This review updates a 2001 Cochrane review, and no relevant new studies were identified, but additional outcomes were sought. Objectives To assess the efficacy and adverse events of single dose dipyrone in acute postoperative pain. Search methods The earlier review searched CENTRAL, MEDLINE, EMBASE, LILACS and the Oxford Pain Relief Database to December 1999. For the update we searched CENTRAL, MEDLINE,EMBASE and LILACS to February 2010. Selection criteria Single dose, randomised, double-blind, placebo or active controlled trials of dipyrone for relief of established moderate to severe postoperative pain in adults. We included oral, rectal, intramuscular or intravenous administration of study drugs. Data collection and analysis Studies were assessed for methodological quality and data extracted by two review authors independently. Summed total pain relief over six hours (TOTPAR) was used to calculate the number of participants achieving at least 50% pain relief. Derived results were used to calculate, with 95% confidence intervals, relative benefit compared to placebo, and the number needed to treat (NNT) for one participant to experience at least 50% pain relief over six hours. Use and time to use of rescue medication were additional measures of efficacy. Information on adverse events and withdrawals was collected. Main results Fifteen studies tested mainly 500 mg oral dipyrone (173 participants), 2.5 g intravenous dipyrone (101), 2.5 g intramuscular dipyrone (99); fewer than 60 participants received any other dose. All studies used active controls (ibuprofen, paracetamol, aspirin, flurbiprofen, ketoprofen, dexketoprofen, ketorolac, pethidine, tramadol, suprofen); eight used placebo controls. Over 70% of participants experienced at least 50% pain relief over 4 to 6 hours with oral dipyrone 500 mg compared to 30% with placebo in five studies (288 participants; NNT 2.4 (1.9 to 3.2)). Fewer participants needed rescue medication with dipyrone (7%) than with placebo (34%; four studies, 248 participants). There was no difference in participants experiencing at least 50% pain relief with 2.5 g intravenous dipyrone and 100 mg intravenous tramadol (70% vs 65%; two studies, 200 participants). No serious adverse events were reported. Authors’ conclusions Based on very limited information, single dose dipyrone 500 mg provides good pain relief to 70% of patients. For every five individuals given dipyrone 500 mg, two would experience this level of pain relief who would not have done with placebo, and fewer would need rescue medication, over 4 to 6 hours. PMID:20824835

Derry, Sheena; Faura, Clara; Edwards, Jayne; McQuay, Henry J; Moore, R Andrew

2014-01-01

106

Nonoperative and postoperative rehabilitation for glenohumeral instability.  

PubMed

The glenohumeral joint is an inherently unstable joint that relies on the interaction of the dynamic and static stabilizers to maintain stability. Disruption of this interplay or poor development of any of these factors may result in instability, pain, and a loss of function. Rehabilitation will vary based on the type of instability present and the key principles described. Whether a course of nonoperative rehabilitation is followed or the patient presents postoperatively, a comprehensive program designed to establish full ROM and balance capsular mobility, in addition to maximizing muscular strength, endurance, proprioception, dynamic stability, and neuromuscular control is essential. A functional approach to rehabilitation using movement patterns and sport-specific positions along with an interval sport program will allow a gradual return to athletics. The focus of the program should minimize the risk of recurrence and ensure that the patient can safely return to functional activities. PMID:24079440

Wilk, Kevin E; Macrina, Leonard C

2013-10-01

107

Acute Postoperative Endophthalmitis Caused by Staphylococcus lugdunensis?  

PubMed Central

Acute postoperative endophthalmitis caused by Staphylococcus lugdunensis is infrequently reported in clinical studies. Five cases of acute postcataract surgery endophthalmitis caused by S. lugdunensis were taken from a multicenter prospective study conducted in four university-affiliated hospitals in France (2004 to 2005). These cases were characterized by severe ocular inflammation occurring with a mean delay of 7.6 days after cataract surgery, severe visual loss (hand motions or less in three cases), and dense infiltration of the vitreous. Each of these patients was initially treated by using a standard protocol with intravitreal (vancomycin and ceftazidime), systemic, and topical antibiotics. Given the severity of the endophthalmitis, even though bacteria were sensitive to intravitreal antibiotics, pars plana vitrectomy was needed in four cases. The final visual prognosis was complicated by severe retinal detachment in three cases. The microbiological diagnosis was reached by using conventional cultures with specific biochemical tests and eubacterial PCR amplification followed by direct sequencing. PMID:17392442

Chiquet, C.; Pechinot, A.; Creuzot-Garcher, C.; Benito, Y.; Croize, J.; Boisset, S.; Romanet, J. P.; Lina, G.; Vandenesch, F.

2007-01-01

108

Nefopam and Ketamine Comparably Enhance Postoperative Analgesia  

PubMed Central

Summary Opioids alone sometimes provide insufficient postoperative analgesia. Co-administration of drugs may reduce opioid use and to improve opioid efficacy. We therefore tested the hypothesis that administration of ketamine or nefopam, to postoperative patients with pain only partly alleviated by morphine, limits the amount of subsequent opioid necessary to produce adequate analgesia. Patients (n=77) recovering from major surgery were given up to 9 mg intravenous morphine. Those still suffering from pain were randomly assigned to blinded administration of: 1) isotonic saline (Control, n=21); 2) ketamine 10 mg (Ketamine, n=22); or, 3) nefopam 20 mg (Nefopam, n=22). Three-mg morphine boluses were subsequently given at 5-minute intervals until adequate analgesia was obtained, or 60 minutes elapsed after the beginning of the study drug administration, or ventilation became insufficient (respiratory rate < 10 breath/minute or saturation by pulse oxymetery < 95%). Supplemental morphine (i.e., after test drug administration) requirements were significantly greater in the Control group [17 ± 10 (SD) mg] than in the Nefopam (10 ± 5 mg, P < 0.005) or Ketamine (9 ± 5 mg, P < 0.001) groups. Morphine titration was successful in all Ketamine and Nefopam patients, but failed in four Control patients (two from respiratory toxicity and two from persistent pain). Tachycardia and profuse sweating were more frequent in patients given nefopam and sedation was greater with ketamine; however, the incidence of other potential complications did not differ between groups. Implications We conclude that ketamine 10 mg and nefopam 20 mg comparably potentiate opioid analgesia, each reducing opioid need by approximately 40%. Ketamine administration was associated with sedation whereas nefopam produced tachycardia and sweating. However, none of the side effects was serious. Either drug can thus be used to potentiate opioid analgesia. PMID:15616073

Kapfer, Barbara; Alfonsi, Pascal; Guignard, Bruno; Sessler, Daniel I.; Chauvin, Marcel

2005-01-01

109

Postoperative IMRT in head and neck cancer  

PubMed Central

Background Aim of this work was to assess loco-regional disease control in head and neck cancer (HNC) patients treated with postoperative intensity modulated radiation therapy (pIMRT). For comparative purposes, risk features of our series have been analysed with respect to histopathologic adverse factors. Results were compared with an own historic conventional radiation (3DCRT) series, and with 3DCRT and pIMRT data from other centres. Between January 2002 and August 2006, 71 patients were consecutively treated with pIMRT for a squamous cell carcinoma (SCC) of the oropharynx (32), oral cavity (22), hypopharynx (7), larynx (6), paranasal sinus (3), and an unknown primary, respectively. Mean and median follow up was 19 months (2–48), and 17.6 months. 83% were treated with IMRT-chemotherapy. Mean prescribed dose was 66.3 Gy (60–70), delivered with doses per fraction of 2–2.3 Gy, respectively. Results 2-year local, nodal, and distant control rates were 95%, 91%, and 96%, disease free and overall survival 90% and 83%, respectively. The corresponding survival rates for the subgroup of patients with a follow up time >12 months (n = 43) were 98%, 95%, 98%, 93%, and 88%, respectively. Distribution according to histopathologic risk features revealed 15% and 85% patients with intermediate and high risk, respectively. All loco-regional events occurred in the high risk subgroup. Conclusion Surgery followed by postoperative IMRT in patients with substantial risk for recurrence resulted in high loco-regional tumor control rates compared with large prospective 3DCRT trials. PMID:17052346

Studer, Gabriela; Furrer, Katrin; Davis, Bernard J; Stoeckli, Sandro S; Zwahlen, Roger A; Luetolf, Urs M; Glanzmann, Christoph

2006-01-01

110

Korrosion und Korrosionsschutz  

Microsoft Academic Search

\\u000a Der Begriff Korrosion leitet sich vom Lateinischen corrodere (zemagen, zerfressen) abo In Deutschland wird er zum ersten Mal 1785 in einer Übersetzung aus dem Französischen tiber die\\u000a Bleiweißherstellung, einem basischen Bleicarbonat, das als Anstrich- und Korrosionsschutzfarbe Anwendung findet, erwähnt.\\u000a Allerdings stammen die ersten Aufzeichnungen über Korrosionsvorgänge bereits aus dem vierten Jahrhundert v. Chr. Der griechische\\u000a Philosoph Plato (428–347 v. Chr.)

Dirk Flottmann; Detlev Forst; Helmut Roßwag

111

Wasser und wässrige Lösungen  

Microsoft Academic Search

\\u000a „Aufgrund der universellen Bedeutung für alle biologischen Prozesse sowie seiner zentralen Eigenschaften als Lösemittel in\\u000a zahlreichen chemischen Reaktionen liegt es nahe, Wasser für eine ganz „normale“ Verbindung zu halten. Gerade wegen seiner\\u000a globalen Präsenz und Verfügbarkeit diente das Wasser mit seinen Eigenschaften denn auch zu Beginn der naturwissenschaftlichen\\u000a Forschung als Normund Vergleichsgröße bei der physikalisch-chemischen Beschreibung anderer Stoffe. Erwähnt sei

Dirk Flottmann; Detlev Forst; Helmut Roßwag

112

Mengen und Relationen  

Microsoft Academic Search

\\u000a Sie können sich bestimmt noch daran erinnern, dass Sie sich irgendwann in den ersten Schuljahren mit Mengen beschäftigt haben.\\u000a Wussten Sie, dass der Mathematiker Georg Cantor (1845–1918), der mehr als 40 Jahre als Professor an der Universität Halle\\u000a tätig war, als Begründer der Mengenlehre (damals noch Mannigfaltigkeitslehre) angesehen wird? Durch ihn kennen wir Begriffe\\u000a wie Äquivalenz und Mächtigkeit von Mengen.

Doina Logof?tu

113

Rating als Strategie- und Risikoberatung für kleine und mittlere Unternehmen  

Microsoft Academic Search

Aufgrund der durch Basel II veränderten Kreditvergabepraxis werden sich die Kreditkonditionen in erheblichem Maße stärker spreizen. Da insbesondere der Mittelstand diese Problematik nicht hinreichend erkannt hat, setzt in Sachsen eine Mittelstandsoffensive mit dem Ziel der Strategie- und Risikoberatung (Rating Advisory) zur Beschäftigungssicherung ein. In diesem Beitrag wird das verwendete Ratingverfahren vorgestellt. Einzigartig sind hierbei die explizite Berücksichtigung der Risiken und

Ulrich Blum; Frank Leibbrand

2003-01-01

114

Der Einfluss von Acker und Waldnutzung auf Boden und Vegetation – ein Zeitvergleich nach 27 Jahren  

Microsoft Academic Search

Zusammenfassung:   Der Einfluss der beiden unterschiedlichen Bodennutzungsformen konventionell bewirtschafteter Acker und forstlich genutzter Laubwald auf die Entwicklung der Bodenazidität, der Gehalte und Vorräte an organischem Kohlenstoff (Corg) und Gesamtstickstoff (Nt) sowie die Artenzusammensetzung der Vegetation wurde an zwei Standorten (Rodheim und Eßfeld) in der mainfränkischen Lösslandschaft im Zeitvergleich nach 27 Jahren quantifiziert. Hierfür wurden acht Parabraunerden und Pseudogley-Parabraunerden aus Löss

J. Rinklebe; F. Makeschin

2003-01-01

115

Factors Associated With Postoperative Delirium After Thoracic Surgery  

Microsoft Academic Search

Background. Postoperative delirium is an acute confu- sional state characterized by fluctuating consciousness and is associated with increased morbidity and mortality. We analyzed the incidence and risk factors of delirium following thoracic surgery. Methods. All patients (n 432) who underwent thora- cotomy or sternotomy from 1996 to 2003 were analyzed retrospectively. The diagnosis of postoperative delirium was based on Diagnostic

Bedrettin Yildizeli; M. Og; Hasan F. Batirel; Kemal Kuscu; Mustafa Yüksel

116

High Risk of Cognitive and Functional Decline after Postoperative Delirium  

Microsoft Academic Search

Background\\/Aims: The aim of the study was to investigate the association of postoperative delirium with the outcomes of cognitive impairment, functional disability and death. Methods: Hip surgery patients aged 60 years or over (n = 200) underwent preoperative and daily postoperative assessment of their cognitive status during hospital stay. Outcome variables were determined at an average of 8 and 38

Horst Bickel; Reiner Gradinger; Eberhard Kochs; Hans Förstl

2008-01-01

117

Postoperative Refraction in the Second Eye Having Cataract Surgery  

PubMed Central

Introduction. Previous cataract surgery studies assumed that first-eye predicted and observed postoperative refractions are equally important for predicting second-eye postoperative refraction. Methods. In a retrospective analysis of 173 patients having bilateral sequential phacoemulsification, multivariable linear regression was used to predict the second-eye postoperative refraction based on refractions predicted by the SRK-T formula for both eyes, the first-eye postoperative refraction, and the difference in IOL selected between eyes. Results. The first-eye observed postoperative refraction was an independent predictor of the second eye postoperative refraction (P < 0.001) and was weighted more heavily than the first-eye predicted refraction. Compared with the SRK-T formula, this model reduced the root-mean-squared (RMS) error of the predicted refraction by 11.3%. Conclusions. The first-eye postoperative refraction is an independent predictor of the second-eye postoperative refraction. The first-eye predicted refraction is less important. These findings may be due to interocular symmetry. PMID:24533181

Leffler, Christopher T.; Wilkes, Martin; Reeves, Juliana; Mahmood, Muneera A.

2011-01-01

118

Beobachtungen über Fremdkörper in Enten- und Bläßhuhnnestern  

Microsoft Academic Search

Zusammenfassung Von 387 Nestern der Stockente(Anas platyrhynchos), Schnatterente(A. strepera), Tafelente(Aythya ferina) und Reiherente(A. fuligula) enthielten 68 (= 17,5%) Fremdkörper, und zwar Steine und Gehäuse von Weinbergschnecken(Helix pomatia). Erstgelege und Nachgelege waren etwa gleichhäufig belegt. Auch vom Bläßhuhn(Fulica atra) konnten einige Nester mit Fremdkörpern gefunden werden.

Einhard Bezzel

1963-01-01

119

Strahlteilungs- und Interferenzexperimente mit Photonenpaaren  

Microsoft Academic Search

Wir führen eine Reihe von elementaren optischen Experimenten mit einem nichtklassischen Lichtfeld durch, das über parametrische Fluoreszenz erzeugt wird und die Besonderheit aufweist, daß die Photonen ausschließlich paarweise auftreten. Beim Auftreffen auf einen verlustfreien, teildurchlässigen Spiegel werden die Photonen eines Paares gemäß einer Binomialverteilung auf das reflektierte und das transmittierte Bündel verteilt. Dieses Ergebnis ist unabhängig vom Kohärenzgrad. Die beobachtete

J. Brendel; R. Lange; E. Mohler; W. Martienssen

1991-01-01

120

Rechnerarchitekturen und Betriebssysteme (CS201)  

E-print Network

Rechnerarchitekturen und Betriebssysteme (CS201): AVR-CPU und -Assembler 7. Oktober 2014 Prof. Dr Seiten!): http://www.atmel.com/ http://www.atmel.com/dyn/resources/prod_documents/DOC0856.PDF AVR Studio, funktioniert unter Wine C-Compiler, IDE: Ubuntu: sudo apt-get install arduino Ubuntu: sudo apt-get install gcc-avr

Vetter, Thomas

121

Diagnosis and monitoring of postoperative recurrence in Crohn's disease.  

PubMed

Despite advances in medical management, many patients with Crohn's disease (CD) require intestinal surgery throughout their lives. Surgery is not a cure, and postoperative recurrence is common in patients with CD. Ileocolonoscopy has been considered to be the gold standard in the diagnosis and monitoring of postoperative recurrence. However, the optimal monitoring strategy for postoperative recurrence has yet to be established. Capsule endoscopy and cross-sectional imaging techniques, including ultrasonography, computed tomography and MRI, have been used in the postoperative setting, and their usefulness in the monitoring of disease activity has been evaluated in recent clinical trials. The value of fecal markers, such as calprotectin and lactoferrin, has been also assessed in several studies. This review was to identify optimized methods for the diagnosis and monitoring of postoperative recurrence in CD. PMID:25030843

Yamamoto, Takayuki

2015-01-01

122

Post-operative Psychosocial Predictors of Outcome in Bariatric Surgery.  

PubMed

Although there are several recent reviews of the pre-operative factors that influence treatment outcome for bariatric surgery, commensurate efforts to identify and review the predictive validity of post-operative variables are lacking. This review describes the post-operative psychosocial predictors of weight loss in bariatric surgery. Results suggest empirical support for post-operative binge eating, uncontrolled eating/grazing, and presence of a depressive disorder as negative predictors of weight loss outcomes; whereas, adherence to dietary and physical activity guidelines emerged as positive predictors of weight loss. With the exception of depression, psychological comorbidities were not consistently associated with weight loss outcomes. Results highlight the need for post-operative assessment of disordered eating and depressive disorder, further research on the predictive value of post-operative psychosocial factors, and development of targeted interventions. PMID:25381119

Sheets, Carrie S; Peat, Christine M; Berg, Kelly C; White, Emily K; Bocchieri-Ricciardi, Lindsey; Chen, Eunice Y; Mitchell, James E

2015-02-01

123

The Role of Postoperative Analgesia in Delirium and Cognitive Decline in Elderly Patients: A Systematic Review  

Microsoft Academic Search

Postoperative delirium and cognitive decline are ad- verse events that occur frequently in elderly patients. Preexisting patient factors, medications, and various intraoperative and postoperative causes have been im- plicated in the development of postoperative delirium and cognitive decline. Despite previous studies identi- fying postoperative pain as a risk factor, relatively few clinical studies have compared the effect of common postoperative

Harold K. Fong; Laura P. Sands; Jacqueline M. Leung

2006-01-01

124

Rollenspiele in George Taboris Holocaust-Stücken "Mein Kampf", "Weisman und Rotgesicht" und "Jubiläum".  

E-print Network

??In dieser Arbeit werden drei Holocaust-Stücke–Mein Kampf, Weisman und Rotgesicht und Jubiläum–des Dramatikers George Tabori auf das Rollenspiel und dessen Funktion hin un-tersucht. Der Autor… (more)

Rohlinger, Sarah Maria

2009-01-01

125

Postoperative atrial fibrillation in liver transplantation.  

PubMed

Postoperative atrial fibrillation (POAF) is common after major surgeries and is associated with increased morbidity and mortality. POAF after liver transplantation (LT) has not been reported. This study was undertaken to investigate the incidence, impact, and risk factors of POAF in LT patients. After IRB approval, LT between January 2006 and August 2013 at our center were retrospectively reviewed. POAF that occurred within 30 days after LT was included. Patients with and without POAF were compared and independent risk factors were identified by logistic regression. Of 1387 adults LT patients, 102 (7.4%) developed POAF during the study period. POAF was associated with significantly increased mortality, graft failure, acute kidney injury and prolonged hospital stay. Independent risk factors included age, body weight, MELD score, presence of previous history of AF, the vasopressors use prior to LT and pulmonary artery diastolic pressure at the end of LT surgery (odds ratios 2.0-7.2, all p?

Xia, V W; Worapot, A; Huang, S; Dhillon, A; Gudzenko, V; Backon, A; Agopian, V G; Aksoy, O; Vorobiof, G; Busuttil, R W; Steadman, R H

2015-03-01

126

Postoperative Systemic Dissemination of Injected Elemental Mercury  

PubMed Central

There were only a few reports of mercury on pulmonary artery. However, there is no data on surgery related mercury dissemination. The objective of the present article is to describe one case of postoperative injected mercury dissemination. A 19-year-old man presented severe neck pain including meningeal irritation sign and abdominal pain after injection of mercury for the purpose of suicide. Radiologic study showed injected mercury in the neck involving high cervical epidural space and subcutaneous layer of abdomen. Partial hemilaminectomy and open mercury evacuation of spinal canal was performed. For the removal of abdominal subcutaneous mercury, C-arm guided needle aspiration was done. After surgery, radiologic study showed disseminated mercury in the lung, heart, skull base and low spinal canal. Neck pain and abdominal pain were improved after surgery. During 1 month after surgery, there was no symptom of mercury intoxication except increased mercury concentration of urine, blood and hair. We assumed the bone work during surgery might have caused mercury dissemination. Therefore, we recommend minimal invasive surgical technique for removal of injected mercury. If open exposures are needed, cautious surgical technique to prohibit mercury dissemination is necessary and normal barrier should be protected to prevent the migration of mercury. PMID:21607187

Kang, Suk-Hyung; Moon, Kyung-Yoon

2011-01-01

127

Undivided attention improves postoperative anesthesia handover recall  

PubMed Central

Background For years, undivided attention during the presurgical “timeout” has been utilized as a precaution to ensure patient safety. The information relayed during the timeout is presented in a confirmatory nature rather than a delegation of new information. However, it is a standard of practice in which all members of the operating theater provide their full and undivided attention. Standards of patient care should be contiguous throughout the preoperative, perioperative, and postoperative stages of surgery. In this manner, it is expected that the same undivided attention afforded during the timeout should be maintained when transferring the patient to the postanesthesia care unit. Methods In this study, information was collected regarding handover of information during the transfer status postsurgical procedures. Data were collected via observing interactions between the anesthesiologist and the nurse during verbal patient transfers. Results This study demonstrated that the presence of undivided attention during the handover of a surgical patient in the postanesthesia care unit has a direct correlation with improved recall of the information discussed during handover. Conclusion Focus is on the quantity of information that can be recalled by the transferring nurse, and whether or not undivided attention affects the outcome. Analysis focuses on suggestions to better improve patient safety and recovery when being transferred in an anesthetic setting. The practice of patient handover should be standardized to better improve the safety and quality of medical care. PMID:25031549

Arenas, Alejandro; Tabaac, Burton J; Fastovets, Galina; Patil, Vinod

2014-01-01

128

Acute postoperative complications of hypospadias repair  

PubMed Central

Purpose Complications in hypospadias surgery are higher than other reconstructive procedures. The incidence of complications can be reduced if proper preventive measures are taken. The review aims to highlight incidences, causes, and preventive measures of acute complications of hypospadias repair. Materials and Methods Literature reports were reviewed in Pubmed by giving the key word acute complications of hypospadias repair, wound infection, wound dehiscence, flap necrosis, edema, penile torsion, urethral fistula, bleeding and hematoma and urethral stents problems. Summaries of all articles were reviewed with full text of relevant article and results were analyzed. Results Besides mentioning the complications of hypospadias repair in individual articles on the subject, we did not come across any separate article on this subject in the published English literature. Fistula is the commonest complication followed by edema and penile torsion. Conclusions Most acute complications can be prevented with adherence to principles of plastic and microsurgery, meticulous preoperative planning, and judicious postoperative care. Deviation from these principles may lead to disaster and even failure of the repair. The aim in hypospadias surgery should be following these principles and bring down the complication rates < 5% in distal hypospadias and < 10% in proximal hypospadias. PMID:19468404

Bhat, Amilal; Mandal, Arup Kumar

2008-01-01

129

Postoperative cognitive dysfunction, Alzheimer's disease, and anesthesia.  

PubMed

Although aging itself is not a disease, there are many comorbidities that become more common with aging. Heart disease, cancer, and other chronic illnesses are either more common or more severe in aging patients. Approximately 5.5 million people in the United States have Alzheimer's disease (AD), with the principal risk factor being age. It is estimated that the incidence of AD diagnosis doubles every 5 years after the age of 65. Therefore, as the population ages, the impact of AD on the healthcare landscape will increase. Understanding how to manage patients with AD is critical as we begin to care for more elderly patients in the perioperative period. In addition to their other health considerations, aging surgical patients are increasingly more likely to have pre-existing AD or be at risk for developing AD. There is growing interest to determine how anesthesia affects the development or progression of AD. Similarly, a best practice for the anesthetic management of patients with AD is not yet defined. Finally, the relationship between AD and susceptibility to or exacerbation of postoperative cognitive dysfunction (POCD) is not well understood. In this review, we will discuss both the clinical and the preclinical data related to anesthesia and AD, describe the overlapping pathophysiology of neurodegeneration and provide some insight into the anesthetic care of patients with AD. PMID:23931049

Arora, Sona S; Gooch, Jennifer L; García, Paul S

2014-04-01

130

[Postoperative hematomas after inguinal hernia repair].  

PubMed

It was done the analysis of the results of 625 open and endoscopic prosthetic and autoplastic hernia repairs made in a planned and emergency basis during the period from 2005 to 2012. The autoplastic group was divided into three subgroups: the plastic by Bassini, Shouldays and Postempski. The prosthesis group was divided into open and endoscopic subgroups. The open prosthesis group was also divided into subgroups in accordance with the options of hernia sac preparation (excised, reseted, untouched) and the reconstruction of the posterior wall of the inguinal canal (without reconstruction, with a single-layer and double-layer plastic). It was noted hematocele scrotum - 19 (3.04%), hematoma of the spermatic cord - 16 (2.56%), wound infiltration with a hemorrhagic component - 13 (2.08%). It was not noted the hemorrhagic complications in the subgroups of open prosthesis without hernia sac preparation. Reducing surgical aggression against inguinal hernias during the operation can reduce the frequency of hematomas. The absence of a clear classification of hematomas brings to difficulties in assessment of the role of specific surgical techniques in the development of postoperative complications after surgery for inguinal hernias. PMID:24429713

Cherepanin, A I; Pokrovski?, K A; Povetkin, A P; Antonov, O N; Baulina, E A

2014-01-01

131

Postoperative radionuclide evaluation of osteoid osteomas.  

PubMed

Five cases of clinically suspected osteoid osteomas were studied by preoperative injection of technetium-99m methylene disphosphonate, intraoperative localization with a radiation-sensitive scintillation probe, and postoperative examination of the entire tissue specimen (including the presumed nidus and surrounding bone). Microradiography and light microscopy were also used. In addition, a new autoradiography technique was introduced in which the excised surgical specimen was placed on undeveloped x-ray film for pathologic localization, diagnosis of the lesions, and a study of the relative intensity of radioactive uptake in the nidus vs. surrounding bone. Autoradiography revealed that the nidus showed the greatest concentration of radioactivity, followed by the surrounding bone. The authors conclude that 99mTc can be used clinically in localizing osteoid osteomas and that preoperative and intraoperative scanning can assist in conservative surgical excision, e.g., minimal extirpation of bone in delicate areas such as the spine. For small lesions, autoradiography assists the pathologist in identifying an osteoid osteoma. PMID:6217488

Ghelman, B; Vigorita, V J

1983-02-01

132

Quantitative Bestimmung der wasserlöslichen Vitamine in verschiedenen Obst- und Gemüsesäften mittels HPLC und massenspektrometrischer Analyse.  

E-print Network

??Die Anreicherung an Vitaminen und zusätzlichen Nährstoffen von Obst- und Gemüsesäften ist in den letzten Jahren gestiegen. Produkthersteller werben gezielt mit hohem, reichhaltigem Vitamingehalt ihrer… (more)

Wagner, Sophie-Marie

2011-01-01

133

Hans Kelsen und Sigmund Freud - Unmittelbare und mittelbare Bezugnahmen sowie mögliche Einflüsse.  

E-print Network

??Die vorliegende Arbeit beschäftigt sich mit der wissenschaftlichen Auseinandersetzung zwischen Hans Kelsen und Sigmund Freud und zielt darauf ab, das transdisziplinäre Interesse der beiden Vertreter… (more)

Huttar, Martina

2011-01-01

134

Early removal of nasogastric tube after cystectomy with urinary diversion: Does postoperative ileus risk increase?  

Microsoft Academic Search

ObjectivesTo examine the risk factors of postoperative ileus and investigate whether the duration of postoperative nasogastric tube (NGT) use affects the rate of postoperative ileus in patients undergoing radical cystectomy with urinary diversion.

Hyoung Keun Park; Cheol Kwak; Seok-Soo Byun; Eunsik Lee; Sang Eun Lee

2005-01-01

135

Despite technological advances in surgery and anesthesia during the last few decades, the incidence of postoperative  

E-print Network

, the incidence of postoperative cognitive dysfunction remains a relatively common compli- cation in surgical evidence on the relationship between postoperative cognitive dysfunctions and the most com- mon . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47 Postoperative cognitive dysfunctions

Mandal, Pravat K.

136

[Postoperative pain management. Aims and organization of a strategy for postoperative acute pain therapy].  

PubMed

The Health Services, not only the Italian one, is under pressure because of request for improving treatment quality and the financial need for reorganization and cost-saving. It's required a rationalization of intervention, together with a careful choice of the best and cheapest techniques and the demonstration of their efficacy. The anaesthesia service activity, in a period of cost rationalization and funds restriction should be aimed to appropriate outcome measures corrected by both patient's risk factors and surgical-anaesthesiological case-mix. The development of a complete strategy for surgical pain management might run into two phases. The first phase, internal and mono-specialistic, should develop like the creation of an Acute Pain Team. The main processes are: focusing the problem (charge of the care), training, information, teaching methodology (timing, methods, drugs, techniques, etc.) and the audit (before and after changes). The main aims are the evaluation of the level of analgesia and pain relief or patient's satisfaction which are partial endpoints useful to demonstrate the improvement and the efficacy of the new pain management strategies. The second phase, multidisciplinary, is directed toward the creation of a Postoperative Evaluation Team. The main objective is to set up a collaborative clinical group able to identify the criteria for quality, efficacy and safety. The major purpose is the evaluation of major outcome measures: surgical outcome, morbidity, mortality and length of hospitalization. The improvement in the quality of postoperative pain treatment goes through a better organization and a progressive increase of the already available therapy. The achievement of the result and the quality projects depend on the interaction among staff members with different behaviours and settings. Internal teaching and training, continuous education for doctors and nurses, and external information, marketing and improvement of attractive capability of Institution, are the procedures of a growing integrated program for postoperative pain treatment. The organizational processes should interact effectively with a plan of education, updating, revision and information in a definite development timing. It should be emphasized a collaborative, interdisciplinary approach to pain control, assessment and treatment, including all the members of the health care team, with an input from the patient and a protective collaboration from the Institution. The development of a postoperative care team must be considered as part of the largest project for "a Painfree Hospital". It represents a keystone of a Institutional Quality Assurance Plan for health care providers, patients (customs) and Institution. PMID:11070958

Nolli, M; Nicosia, F

2000-09-01

137

Preoperative and postoperative care in cosmetic laser resurfacing  

NASA Astrophysics Data System (ADS)

Advances in laser technology have allowed the application of lasers to cosmetic facial skin resurfacing. While this application has been extremely advantageous to patients, the development of pre- and postoperative therapeutic regimens was necessary to mitigate potential complications associated with laser resurfacing. Potential complications of laser resurfacing include prolonged postoperative erythema, hyperpigmentation, hypopigmentation, herpetic, bacterial or candidal infection, and other concerns including scarring and abnormal wound healing. In this report we review the state of the art of preoperative and postoperative care for cosmetic laser resurfacing.

Ross, Adam T.; Becker, Daniel G.

2001-05-01

138

[Post-operative pain management in orthopaedic surgery and traumatology].  

PubMed

Provision of sufficient post-operative pain therapy is an obligation in the clinical management of patients. A wide range of medical, technical and organizational options is used to improve post-operative pain management in orthopaedic surgery. Measurement of pain is as important as the correct use of analgesics and application techniques. Standardized pain therapy algorithms should facilitate autonomous treatment of patients. Additional procedures like patient-controlled analgesia or local catheter for pain are necessary for individualized or operation-specific pain therapy. The balanced combination in postoperative pain therapy could reduce side effects and complication rates, increase mobility and enhance patient satisfaction. PMID:16435112

Giesa, M; Jage, J; Meurer, A

2006-02-01

139

UniReport Satzungen und Ordnungen vom 16.04.2013 1 Ordnung des Fachbereichs Psychologie und Sportwissenschaften an der  

E-print Network

/ Clinical Exercise Physiology" (,,Sportmedizinisches Trai- ning und Leistungsphysiologie") mit dem Abschluss Sports Medical Training / Clinical Exercise Physiology (Sportmedizinisches Training und Exercise Physiology (Sportmedizinisches Training und Leistungsphysiologie) #12;UniReport Satzungen und

140

Bewegungsapparat: Postcraniales Skelett und Muskulatur  

NASA Astrophysics Data System (ADS)

Der Bewegungsapparat bestimmt die Form des Wirbeltierkörpers. So lässt sich z. B. aus der Gestalt eines Fisches auf seine bevorzugt e Schwimmweise schließen (S. 61). Bei den aquatisch en Schädeltieren dominiert die Fortbewegung mit axialem Antrieb; bei den meisten Tetrapoda findet sich eine Kombination aus axialem Antrieb und Bewegung durch Gliedmaßen. Selbst beim höchst spezialisierten Gang, der bipeden Bewegung des Menschen, sind Torsionsbewegungen des Rumpfes noch maßgeblich und bestimmen auch die Grundform des menschlichen Körpers (z. B. die Taille). Obwohl die verschiedenen Antriebsmechanismen eine funktionelle Einheit bilden, werden im Folgenden das Axialskelett sowie der Schulter- und Beckengürtel mit den zugehörigen Extremitäten getrennt besprochen.

Fischer, Martin S.

141

Bilateral postoperative maxillary cysts after orthognathic surgery: A case report.  

PubMed

Postoperative maxillary cysts are locally aggressive lesions, usually developing as delayed complications many years after radical antral surgery. This report describes a case of bilateral postoperative maxillary cysts following orthognathic surgery performed approximately 21 years previously. The patient complained of stinging pain on her right cheek. Radiographic examination revealed low-attenuation lesions on both maxillary sinuses with discontinuously corticated margins without distinct expansion or bone destruction. The cysts were enucleated with the removal of metal plates and screws for pain relief. Histopathological examination confirmed the diagnosis of postoperative maxillary cysts lined by ciliated, pseudostratified columnar cells. The patient has remained asymptomatic thus far, and there was no evidence of local recurrence at 21 months of postoperative follow-up. PMID:25473641

Lee, Jung-Hye; Huh, Kyung-Hoe; Yi, Won-Jin; Heo, Min-Suk; Lee, Sam-Sun; Choi, Soon-Chul

2014-12-01

142

Postoperative exposure of bioresorbable GTR membranes: effect on healing results  

Microsoft Academic Search

The goal of this investigation was to evaluate the effect of postoperative exposure of two different bioresorbable membranes\\u000a on the guided tissue regeneration (GTR) healing results compared to nonexposed sites. In each of 25 patients one pair of contralateral\\u000a intrabony lesions was treated either with polylactic acid (PLA) or polyglactin 910 (PG-910) membranes. Postoperative exposure\\u000a occurred in 9 PLA and

M. Christgau; N. Bader; G. Schmalz; K.-A. Hiller; A. Wenzel

1997-01-01

143

Delayed incidental diagnosis of postoperative extradural hematoma following ventriculoperitoneal shunt  

PubMed Central

Ventriculo peritoneal (VP) shunt uncommonly complicates as intracranial hematomas which can still occur in patients with a functioning VP shunt leading to a delay in the diagnosis which can be extremely dangerous and lead to adverse outcomes. We report a case of an incidental diagnosis of delayed post-operative EDH following VP shunt in an young adult patient with a right cerebellar lesion and highlight the need for meticulous post-operative neurological examination. PMID:25552861

Byrappa, Vinay; Redhu, Shruti; Varadarajan, Bhadrinarayan

2015-01-01

144

Laminectomy: effects on postoperative technetium and gallium scintigraphy  

SciTech Connect

Bone scans using Tc-99m diphosphonate were found to become abnormal within 2 weeks after laminectomy in less than half of patients regardless of the extent of the operation. The degree of new uptake equaled that of the sacroiliac joints in only one of 19 patients with a normal preoperative scan. However, the Ga-67 citrate scan usually became abnormal (89%) postoperatively. Thus the Tc-99m bone scan may be helpful in detecting postoperative infection.

Silberstein, E.B.; Schneider, H.J.; Khodadad, G.; DeVries, D.; Rauf, G.C.; Noll, R.

1984-06-01

145

Postoperative delirium following gastrointestinal surgery in elderly patients  

Microsoft Academic Search

Postoperative delirium is a common complication which can interfere with the surgical treatment and recovery of elderly patients,\\u000a and is likely to prolong their hospitalization. Unfortunately, there is as yet no completely effective pre- and\\/or post operative\\u000a technique of patient care to reduce or prevent postoperative delirium. In this study, 36 patients aged over 70 years undergoing\\u000a gastrointestinal operations were

Tetsuya Kaneko; Sadamu Takahashi; Takuji Naka; Yasuaki Hirooka; Yuichi Inoue; Nobuaki Kaibara

1997-01-01

146

Führung und Verantwortung – eine Verwechslung?  

Microsoft Academic Search

\\u000a Die Unternehmensplanung ist ein Entscheidungs- und Informationsverarbeitungsprozess, in ihrer subjektiven Aussage aber die\\u000a Willensäußerung der Manager, Führungsleistungen zu erbringen, denen bestimmte qualitative und quantitative Größen zugrunde\\u000a liegen. Soll die Planung als System subjektiver Führungsziele aufgefasst werden, ist das Planungsverfahren in der Weise zu\\u000a gestalten, dass sich die Führungskräfte selber als die wesentlichen Elemente des Prozedere verstehen. Vorerst ist deshalb\\u000a nach

Peter Maier

147

Nichtsteroidale Antirheumatika (NSAR) in der perioperativen Phase in Traumatologie und Orthopädie  

Microsoft Academic Search

Zusammenfassung\\u000a Ziel  Erreichen eines analgetischen, antiphlogistischen und antipyretischen Effekts in der Traumatologie und Orthopdie ohne oder\\u000a mit mglichst wenig Nebenwirkungen, unter spezieller Bercksichtigung der Knochenheilung.\\u000a \\u000a \\u000a \\u000a Indikationen  Akute und chronische Entzndungen, z. B. Rheuma, Spondylitis ankylosans.\\u000a \\u000a Degenerative Gelenkerkrankungen.\\u000a \\u000a \\u000a Posttraumatische und postoperative Schmerzen, dem oder Fieber.\\u000a \\u000a \\u000a Prophylaxe gegen heterotope Ossifikationen.\\u000a \\u000a \\u000a \\u000a \\u000a Kontraindikationen  berempfindlichkeit.\\u000a \\u000a Gastrointestinale Ulzeration oder Blutung.\\u000a \\u000a \\u000a Schwere Leber- oder Nierenfunktionsstrung.\\u000a \\u000a \\u000a \\u000a \\u000a Ergebnisse  Nichtsteroidale Antirheumatika (NSAR) sind wertvolle

Alexander Beck; Khaled Salem; Gert Krischak; Lothar Kinzl; Mark Bischoff; Andreas Schmelz

2005-01-01

148

Machine Vision Preis Vielseitig, wachstumsstark und zukunftssicher  

E-print Network

Machine Vision Preis Vielseitig, wachstumsstark und zukunftssicher: Sehende Maschinen! Jetzt den richtigen Weg einschlagen, Machine Vision zu deinem Thema machen und die Chance zum Erfolg nutzen beim: Machine Vision, also sehende Systeme, die das menschliche Auge nachahmen, stellen eine moderne

Haller-Dintelmann, Robert

149

Zytogenetische Untersuchungen an Falconiformes und Ciconiiformes  

Microsoft Academic Search

Vergleichende genotypische Untersuchungen ergaben, daß die Neuweltgeier als konvergente Entwicklung und nicht als Verwandte der Altweltgeier anzusehen sind und, wie bereitsKönig vorschlug, deshalb bei den Ciconiiformes einzureihen sind.

A. Herzog; Henni Höhn; B. Matern

1986-01-01

150

Hamburgs Familienunternehmen Unternehmertum und Unternehmergeist einer Handelsmetropole  

E-print Network

32 REIHE 18 Hamburgs Familienunternehmen Unternehmertum und Unternehmergeist einer Handelsmetropole Einblick in die Geschichte und Tradition Hamburger Familien- unternehmer gegeben werden. Unternehmer, beide Hamburger Institut für Familienunter- nehmen (HIF) Prof. Dr. Günther Strunk, Hamburger Institut

Hamburg,.Universität

151

Physik gestern und heute Das Eiskalorimeter  

Microsoft Academic Search

Kalorimetrische Messungen gehören heute zum experimentellen Standardrepertoire im Bereich der Thermodynamik und der physikalischen Chemie. Das erste Gerät für derartige Messungen entwickelten Ende des 18. Jahrhunderts die französischen Wissenschaftler Antoine Laurent Lavoisier und Pierre Simon de Laplace.

P. Heering

2003-01-01

152

Physik gestern und heute Das Eiskalorimeter  

NASA Astrophysics Data System (ADS)

Kalorimetrische Messungen gehören heute zum experimentellen Standardrepertoire im Bereich der Thermodynamik und der physikalischen Chemie. Das erste Gerät für derartige Messungen entwickelten Ende des 18. Jahrhunderts die französischen Wissenschaftler Antoine Laurent Lavoisier und Pierre Simon de Laplace.

Heering, P.

2003-07-01

153

Survival after postoperative morbidity: a longitudinal observational cohort study†  

PubMed Central

Background Previous studies have suggested that there may be long-term harm associated with postoperative complications. Uncertainty exists however, because of the need for risk adjustment and inconsistent definitions of postoperative morbidity. Methods We did a longitudinal observational cohort study of patients undergoing major surgery. Case-mix adjustment was applied and morbidity was recorded using a validated outcome measure. Cox proportional hazards modelling using time-dependent covariates was used to measure the independent relationship between prolonged postoperative morbidity and longer term survival. Results Data were analysed for 1362 patients. The median length of stay was 9 days and the median follow-up time was 6.5 yr. Independent of perioperative risk, postoperative neurological morbidity (prevalence 2.9%) was associated with a relative hazard for long-term mortality of 2.00 [P=0.001; 95% confidence interval (CI) 1.32–3.04]. Prolonged postoperative morbidity (prevalence 15.6%) conferred a relative hazard for death in the first 12 months after surgery of 3.51 (P<0.001; 95% CI 2.28–5.42) and for the next 2 yr of 2.44 (P<0.001; 95% CI 1.62–3.65), returning to baseline thereafter. Conclusions Prolonged morbidity after surgery is associated with a risk of premature death for a longer duration than perhaps is commonly thought; however, this risk falls with time. We suggest that prolonged postoperative morbidity measured in this way may be a valid indicator of the quality of surgical healthcare. Our findings reinforce the importance of research and quality improvement initiatives aimed at reducing the duration and severity of postoperative complications. PMID:25012586

Moonesinghe, S. R.; Harris, S.; Mythen, M. G.; Rowan, K. M.; Haddad, F. S.; Emberton, M.; Grocott, M. P. W.

2014-01-01

154

The role of postoperative radiotherapy in prostate cancer patients  

PubMed Central

Aim of the study The aim of the study was to evaluate the effectiveness of postoperative radiotherapy in prostate cancer patients with unfavorable prognostic factors. Material and methods In the years 2002–2008, 121 consecutive prostate cancer patients underwent radical prostatectomy and postoperative radiotherapy. The median dose was 64 Gy (range: 60–72 Gy). Biochemical and clinical progression-free survival were estimated. Univariate and multivariate analyses were used to analyze clinicopathological variables associated with treatment failure. Results The median follow-up was 27 months. Three-year bPFS was 72%. On univariate analysis it was influenced by: extracapsular tumor extension (60% vs. 75%, p = 0.0232), seminal vesicles invasion (52% vs. 85%, p = 0.00041), Gleason score ? 7 (65% vs. 86%, p = 0.044) and the use of hormonal therapy (50% vs. 80%, p = 0.0058). On multivariate analysis bPFS was associated with: TNM stage (HR = 3.19), postoperative hormonal therapy (HR = 2.6), total irradiation dose (HR = 0.82) and the maximum pretreatment level of prostate-specific antigen (PSA) (HR = 0.95). Three-year cPFS was 84%. On univariate analysis it was influenced by: preoperative PSA level > 10 ng/ml (75% vs. 90%, p = 0.04), vascular-nerve bundles involvement (63% vs. 88%, p = 0.0031), adjacent organs infiltration (50% vs. 85%, p = 0.018) and the use of postoperative hormonal therapy (62% vs. 90%, p = 0.02). On multivariate analysis cPFS was associated with: TNM stage (HR = 2.68), postoperative hormonal therapy (HR = 3.61) and total irradiation dose (HR = 0.78). Conclusions Postoperative radiotherapy in patients with unfavorable prognostic factors provides good biochemical and local control. Total irradiation dose and postoperative hormonal therapy are important treatment factors influencing prognosis. PMID:24596529

Zarzycka, Ma?gorzata; Wi?niewski, Tomasz; Windorbska, Wies?awa; ?yromska, Agnieszka; Wolski, Zbigniew

2013-01-01

155

Mythen, Märchen und Moneten – Texte in Geschäftsberichten: Was sie wollen und wie sie entstehen  

Microsoft Academic Search

\\u000a Texte in Geschäftsberichten sind so vielfältig wie die Autorenschaft und deren Erfahrungen und Motive. Auf der Seite der Leserinnen\\u000a und Leser sind die Ansprüche ebenso differenziert, und sie haben sich in den letzten Jahren stark gewandelt. Der Autor des\\u000a vorliegenden Beitrags ist Praktiker, der auf 20 Jahre Erfahrung mit Geschäftsberichten blickt. Er will Anstösse liefern und\\u000a die Wissenschaft motivieren, dieses

Werner Rudolf

156

Medienbildung im Spannungsfeld alltäglicher Handlungsmuster und Unterrichtsstrukturen  

Microsoft Academic Search

SchülerInnen sind Fan von Yu-Gi-Oh!, dem FC Bayern München, Diddl, Gute Zeiten Schlechte Zeiten, Eisenbahnen und noch vielem\\u000a mehr. Dabei eignen sie sich Wissen in teils erstaunlichem Umfang und Detail an und werden zu Experten auf einem Spezialgebiet.\\u000a Solches Wissen jedoch bleibt in der Schule häufig außen vor, möglicherweise, weil es mit Unterhaltung und Spaß konnotiert\\u000a ist. Sicher ist jedoch,

Judith Seipold; Klaus Rummler; Julia Rasche

157

Fakult at f ur Physik und Astronomie  

E-print Network

Klima verbraucht man weniger Kraft f Ë? ur den Kampf mit der Natur, und darum sind dort auch die Menschen kleine Birke setze und dann zusehe, wie sie grË? unt und sich im Winde wiegt, dann erf Ë? ullt sich meine

158

Preoperative anxiety and emergence delirium and postoperative maladaptive behaviors.  

PubMed

Based on previous studies, we hypothesized that the clinical phenomena of preoperative anxiety, emergence delirium, and postoperative maladaptive behavioral changes were closely related. We examined this issue using data obtained by our laboratory over the past 6 years. Only children who underwent surgery and general anesthesia using sevoflurane/O(2)/N(2)O and who did not receive midazolam were recruited. Children's anxiety was assessed preoperatively with the modified Yale Preoperative Anxiety Scale (mYPAS), emergence delirium was assessed in the postanesthesia care unit, and behavioral changes were assessed with the Post Hospital Behavior Questionnaire (PHBQ) on postoperative days 1, 2, 3, 7, and 14. Regression analysis showed that the odds of having marked symptoms of emergence delirium increased by 10% for each increment of 10 points in the child's state anxiety score (mYPAS). The odds ratio of having new-onset postoperative maladaptive behavior changes was 1.43 for children with marked emergence status as compared with children with no symptoms of emergence delirium. A 10-point increase in state anxiety scores led to a 12.5% increase in the odds that the child would have a new-onset maladaptive behavioral change after the surgery. This finding is highly significant to practicing clinicians, who can now predict the development of adverse postoperative phenomena, such as emergence delirium and postoperative behavioral changes, based on levels of preoperative anxiety. PMID:15562048

Kain, Zeev N; Caldwell-Andrews, Alison A; Maranets, Inna; McClain, Brenda; Gaal, Dorothy; Mayes, Linda C; Feng, Rui; Zhang, Heping

2004-12-01

159

Postoperative sleep disruptions: a potential catalyst of acute pain?  

PubMed

Despite the substantial advances in the understanding of pain mechanisms and management, postoperative pain relief remains an important health care issue. Surgical patients also frequently report postoperative sleep complaints. Major sleep alterations in the postoperative period include sleep fragmentation, reduced total sleep time, and loss of time spent in slow wave and rapid eye movement sleep. Clinical and experimental studies show that sleep disturbances may exacerbate pain, whereas pain and opioid treatments disturb sleep. Surgical stress appears to be a major contributor to both sleep disruptions and altered pain perception. However, pain and the use of opioid analgesics could worsen sleep alterations, whereas sleep disruptions may contribute to intensify pain. Nevertheless, little is known about the relationship between postoperative sleep and pain. Although the sleep-pain interaction has been addressed from both ends, this review focuses on the impact of sleep disruptions on pain perception. A better understanding of the effect of postoperative sleep disruptions on pain perception would help in selecting patients at risk for more severe pain and may facilitate the development of more effective and safer pain management programs. PMID:24074687

Chouchou, Florian; Khoury, Samar; Chauny, Jean-Marc; Denis, Ronald; Lavigne, Gilles J

2014-06-01

160

Perioperative management in order to minimise postoperative delirium and postoperative cognitive dysfunction: Results from a Swedish web-based survey  

PubMed Central

Cognitive side-effects such as emergence agitation (EA), postoperative delirium (POD) and postoperative cognitive dysfunction (POCD) are not infrequently complicating the postoperative care especially in elderly and fragile patients. The aim of the present survey was to gain insight regarding concern and interest in prevention and treatment strategies for postoperative delirium and dysfunction, and the use of EEG-based depth-of-anaesthesia monitoring possibly reducing the risk for cognitive side effects among anaesthesia personnel. Methods A web-based validated questionnaire was sent to all Swedish anaesthesiologists and nurse anaesthetists during summer 2013. The questionnaire consisted of 3 sections, subjective preferences, routines and practices related to the perioperative handling of EA, POD, POCD. Results The response rate was 52%. Cardiovascular/pulmonary risks where assessed as importance by 98, 97% of responders while 69% considered the risk of neurocognitive side-effects important. When asked explicitly around cognitive side-effects 89%, 37% and 44% assessed awareness, POC and POD respectively of importance. EEG-based depth-of-anaesthesia monitors were used in 50% of hospitals. The responders were not convinced about the benefits of such monitors even in at-risk patients. Structured protocols for the management of postoperative cognitive side-effects were available only in few hospitals. Conclusion Swedish anaesthesia personnel are concerned about the risk of postoperative cognitive side-effects but are more concerned about cardiovascular/pulmonary risks, pain, PONV and the rare event of awareness. Most respondents were not convinced about the use of depth-of-anaesthesia monitors. There is a need to improve knowledge around risk factors, prevention and management of postoperative cognitive side effects. PMID:25568795

Jildenstål, Pether K.; Rawal, Narinder; Hallén, Jan L.; Berggren, Lars; Jakobsson, Jan G.

2014-01-01

161

Erkennen und Bewerten von Dysfunktionen und Schmerzphänomenen im kraniomandibulären System  

Microsoft Academic Search

Zusammenfassung  \\u000a Der logische Aufbau der Untersuchungssequenz erlaubt die volle Integration des Systems in die tägliche Praxis. Sie schafft\\u000a ein Maximum an diagnostischer Sicherheit. Dabei lebt die Sicherheit der Aussagen aus der Untersuchungskaskade von der Menge\\u000a und Qualität der von jedem einzelnen Arzt durchgeführten Untersuchungen und der darauf aufbauenden Therapie.\\u000a \\u000a \\u000a \\u000a Die genaue Differenzierung der Funktionsstörungen des kraniomandibulären Systems (CMS) in dento-\\/okklusogene,

S. Kopp; W. G. Sebald; G. Plato

2000-01-01

162

Early Postoperative 24-Hour Continuous Jejunostomy Feeding in Esophagectomy Patients  

PubMed Central

Esophagectomy can result in various postoperative nutrition-related complications that may impair the nutritional status of the patient. In our institution, we usually initiate 16-hour continuous jejunostomy feeding using an enteral feeding pump on postoperative day 2 as a routine protocol after esophagectomy. The target calorie intake was achieved in 6-7 days with this protocol, which is longer than that required with other recently reported feeding protocols. Accordingly, early jejunostomy feeding protocol, which starts on postoperative day 1 and continues for 24 hours was attempted. In the present report, we described 3 cases of early 24-hour continuous jejunostomy feeding after esophagectomy. The use of this new protocol reduced the duration required to achieve the target calorie intake as less than 5 days without any enteral feeding-related complications. PMID:24527423

Lim, Jeong Hyun; Ju, Dal Lae; Hwang, Yoohwa

2014-01-01

163

Early postoperative feeding in resectional gastrointestinal surgical cancer patients  

PubMed Central

Malnutrition is present in the majority of patients presenting for surgical management of gastrointestinal malignancies, due to the effects of the tumour and preoperative anti-neoplastic treatments. The traditional practice of fasting patients until the resumption of bowel function threatens to further contribute to the malnutrition experienced by these patients. Furthermore, the rationale behind this traditional practice has been rendered obsolete through developments in anaesthetic agents and changes to postoperative analgesia practices. Conversely, there is a growing body of literature that consistently demonstrates that providing oral or tube feeding proximal to the anastomosis within 24 h postoperatively, is not only safe, but might be associated with significant benefits to the postoperative course. Early post operative feeding should therefore be adopted as a standard of care in oncology patients undergoing gastrointestinal resections. PMID:21160596

Osland, Emma J; Memon, Muhammed Ashraf

2010-01-01

164

Postoperative radiotherapy in localized non-small cell lung cancer.  

PubMed

Surgery alone can cure 40-85% of patients with localized non-small cell lung cancer, depending on tumor stage and metastatic lymph-node involvement. As local failure rates occur in up to 50% of the cases, postoperative radiotherapy as an adjuvant treatment option has been evaluated in several trials. This review briefly summarizes the published data mainly from randomized trials. While most of the studies showed a decrease in local recurrence rate, especially in stage-III/N2 tumors after postoperative radiotherapy, no impact could be shown on overall survival. In early stages a detrimental effect of postoperative radiotherapy has been postulated, but those findings have to be interpreted with caution as radiation techniques used were suboptimal and probably not today's state of the art. A carefully designed randomized trial using modern radiotherapy techniques is warranted to define the impact of irradiation on completely resected NSCLC. PMID:11576705

Rübe, C; Phu Nguyen, T; Fleckenstein, J; Niewald, M

2001-09-01

165

Association of Preoperative Biliary Drainage With Postoperative Outcome Following Pancreaticoduodenectomy  

PubMed Central

Objective To determine whether preoperative biliary instrumentation and preoperative biliary drainage are associated with increased morbidity and mortality rates after pancreaticoduodenectomy. Summary Background Data Pancreaticoduodenectomy is accompanied by a considerable rate of postoperative complications and potential death. Controversy exists regarding the impact of preoperative biliary instrumentation and preoperative biliary drainage on morbidity and mortality rates after pancreaticoduodenectomy. Methods Two hundred forty consecutive cases of pancreaticoduodenectomy performed between January 1994 and January 1997 were analyzed. Multiple preoperative, intraoperative, and postoperative variables were examined. Pearson chi square analysis or Fisher’s exact test, when appropriate, was used for univariate comparison of all variables. Logistic regression was used for multivariate analysis. Results One hundred seventy-five patients (73%) underwent preoperative biliary instrumentation (endoscopic, percutaneous, or surgical instrumentation). One hundred twenty-six patients (53%) underwent preoperative biliary drainage (endoscopic stents, percutaneous drains/stents, or surgical drainage). The overall postoperative morbidity rate after pancreaticoduodenectomy was 48% (114/240). Infectious complications occurred in 34% (81/240) of patients. Intraabdominal abscess occurred in 14% (33/240) of patients. The postoperative mortality rate was 5% (12/240). Preoperative biliary drainage was determined to be the only statistically significant variable associated with complications (p = 0.025), infectious complications (p = 0.014), intraabdominal abscess (p = 0.022), and postoperative death (p = 0.037). Preoperative biliary instrumentation alone was not associated with complications, infectious complications, intraabdominal abscess, or postoperative death. Conclusions Preoperative biliary drainage, but not preoperative biliary instrumentation alone, is associated with increased morbidity and mortality rates in patients undergoing pancreaticoduodenectomy. This suggests that preoperative biliary drainage should be avoided whenever possible in patients with potentially resectable pancreatic and peripancreatic lesions. Such a change in current preoperative management may improve patient outcome after pancreaticoduodenectomy. PMID:10450725

Povoski, Stephen P.; Karpeh, Martin S.; Conlon, Kevin C.; Blumgart, Leslie H.; Brennan, Murray F.

1999-01-01

166

Epidural and intravenous bolus morphine for postoperative analgesia in infants  

Microsoft Academic Search

Purpose  To compare two doses of bolus epidural morphine with bolus iv morphine for postoperative pain after abdominal or genitourinary\\u000a surgery in infants.\\u000a \\u000a \\u000a \\u000a Methods  Eighteen infants were randomly assigned to bolus epidural morphine (0.025 mg · kg?1 or 0.050 mg · kg?1) or bolus iv morphine (0.050–0.150 mg · kg?1). Postoperative pain was assessed and analgesia provided, using a modified infant pain

Charles M. Haberkern; Anne M. Lynn; Jeremy M. Geiduschek; Mary Kay Nespeca; Lawrence E. Jacobson; Susan L. Bratton; Maureen Pomietto

1996-01-01

167

Postoperative atrial fibrillation: incidence, mechanisms, and clinical correlates.  

PubMed

Atrial fibrillation is the most commonly encountered arrhythmia after cardiac surgery. Although usually self-limiting, it represents an important predictor of increased patient morbidity, mortality, and health care costs. Numerous studies have attempted to determine the underlying mechanisms of postoperative atrial fibrillation (POAF) with varied success. A multifactorial pathophysiology is hypothesized, with inflammation and postoperative ?-adrenergic activation recognized as important contributing factors. The management of POAF is complicated by a paucity of data relating to the outcomes of different therapeutic interventions in this population. This article reviews the literature on epidemiology, mechanisms, and risk factors of POAF, with a subsequent focus on the therapeutic interventions and guidelines regarding management. PMID:25443241

Yadava, Mrinal; Hughey, Andrew B; Crawford, Thomas Christopher

2014-11-01

168

Zur Ätiologie und operativen Therapie der Osgood-Schlatterschen Tibiaapophysenstörung  

Microsoft Academic Search

Die nach Osgood und Schlatter benannten Ossifikationsstörungen an der Tuberositas Tibiae Jugendlicher werden an 3 Patienten in Symptomengemeinschaft mit anderen bekannten und jeweils abgegrenzten Epiphysenstörungen gezeigt und gleichsam als Zweige eines Baumes und zwar einer endogen bedingten Epiphysenknorpelschwäche angesehen. Nach dem klinischen und röntgenologischen Befund werden auch „Übergangsformen“ herausgestellt als Anfang einer Variationsbreite.

Fritz Klopfer

1952-01-01

169

Preoperative administration of intramuscular dezocine reduces postoperative pain for laparoscopic cholecystectomy  

PubMed Central

Postoperative pain is the most common complaint after laparoscopic cholecystectomy. This study was carried out to evaluate whether preoperative administration of intramuscular dezocine can provide postoperative analgesia and reduce postoperative opioid consumption in patients undergoing laparoscopic cholecystectomy. Patients (ASA I or II) scheduled for laparoscopic cholecystectomy were randomly assigned into intramuscular dezocine group (group 1) or intramuscular normal saline group (group 2). Dezocine and equal volume normal saline were administered intramuscularly 10 min before the induction of anesthesia. After operation, the severity of postoperative pain, postoperative fentanyl requirement, incidence and severity of side-effects were assessed. Postoperative pain and postoperative patient-controlled fentanyl consumption were reduced significantly in group 1 compared with group 2. The incidence and severity of side effects were similar between the two groups. Preoperative single-dose administration of intramuscular dezocine 0.1 mg/kg was effective in reducing postoperative pain and postoperative patient-controlled fentanyl requirement in patients undergoing laparoscopic cholecystectomy. PMID:23554711

Zhu, Yaomin; Jing, Guixia; Yuan, Wei

2011-01-01

170

The effect of postoperative positive end-expiratory pressure on postoperative bleeding after off-pump coronary artery bypass grafting  

PubMed Central

Introduction To compare postoperative prophylactic use of two positive end-expiratory pressure (PEEP) levels in order to prevent postoperative bleeding in patients undergoing off-pump coronary artery bypass grafting (CABG) surgery. Material and methods Sixty patients undergoing an elective off-pump CABG operation were included in this prospective, nonrandomized clinical trial. Patients were divided into two groups as receiving either 5 cm H2O (group 1) or 8 cm H2O PEEP (group 2) after the operation until being extubated. Chest tube outputs, use of blood products and other fluids, postoperative hemoglobin levels, accumulation of pleural and pericardial fluid after the removal of chest tubes, and duration of hospital stay were recorded and compared. Results Low- and high-pressure PEEP groups did not differ with regard to postoperative chest tube outputs, amounts of transfusions and crystalloid/colloid infusion requirements, or postoperative hemoglobin levels. However, low-pressure PEEP application was associated with significantly higher pleural (92 ±37 ml vs. 69 ±29 ml, p = 0.03) and pericardial fluid (17 ±5 ml vs. 14 ±6 ml, p = 0.04) accumulation. On the other hand, high-pressure PEEP application was associated with significantly longer duration of hospitalization (6.25 ±1.21 days vs. 5.25 ±0.91 days, p = 0.03). Conclusions Prophylactic administration of postoperative PEEP levels of 8 cm H2O, although safe, does not seem to reduce chest-tube output or transfusion requirements in off-pump CABG when compared to the lower level of PEEP. Further studies with larger sample sizes are warranted to confirm the benefits and identify ideal levels of PEEP administration in this group of patients. PMID:25395944

Salihoglu, Ece; Celik, Sezai; Ugurlucan, Murat; Caglar, Ilker Murat; Turhan-Caglar, Fatma Nihan; Isik, Omer

2014-01-01

171

Lineare und verzweigte Blockcopolymere aus Polypeptiden und synthetischen Polymeren  

NASA Astrophysics Data System (ADS)

Die vorliegende Arbeit beschäftigt sich mit der Synthese und den Eigenschaften von linearen und verzweigten amphiphilen Polypeptid-Blockcopolymeren. Die Frage nach dem Einfluss der Topologie und Konformation der Blockcopolymere auf die supramolekularen und kolloidalen Eigenschaften bildete einen wichtigen Aspekt bei den Untersuchungen. Die Blockcopolymere wurden nach einem mehrstufigen Reaktionsschema durch Kombination von anionischer und ringöffnender Polymerisation von Aminosäuren-N-Carboxyanhydriden (NCA) synthetisiert. Die Untersuchung der Polypeptid-Blockcopolymere hinsichtlich ihres Aggregationsverhaltens in fester Phase sowie in verdünnter wässriger Lösung erfolgte mittels Streumethoden (SAXS, WAXS, DLS) sowie abbildender Methoden (TEM). Durch Einsatz der Blockcopolymere als polymere Stabilisatoren in der Emulsionspolymerisation wurden Oberflächen funktionalisierte Latizes erhalten. Als Beispiel für eine pharmazeutische Anwendung wurden bioverträgliche Polypeptid-Blockcopolymere als Wirkstoff-Trägersysteme in der Krebstherapie eingesetzt. This work describes the synthesis and characterization of linear and branched polypeptide block copolymers having amphiphilic character. The studies focused on the impact of the block copolymers' conformation and architecture on the supramolecular and colloidal properties. The polypeptide block copolymers were prepared in a multi-step process involving the anionic synthesis of (poly)amino-functional polymers (polystyrene and polybutadiene) which where used as macroinitiators for the ring-opening polymerization of N-carboxyanhydrides (NCA) of protected a-aminoacids. Supramolecular structures of the block copolymers in the solid state as well as in diluted aqueous solution were investigated using scattering (SAXS, WAXS, DLS) and microscopic (TEM) methods. Both linear and branched polypeptide block copolymers were used as polymeric stabilizers in the emulsion polymerization of styrene to yield polypeptide-decorated latexes. Biocompatible block copolymers were used as drug-delivery systems in lymphatic cancer therapy.

Kukula, Hildegard

2001-07-01

172

Must early postoperative oral intake be limited to laparoscopy?  

Microsoft Academic Search

PURPOSE: This prospective, randomized study was designed to evaluate whether or not early postoperative feeding (claimed as a unique benefit of laparoscopic surgery) is possible after laparotomy and colorectal resection. METHODS: The trial was performed between July 1, 1992 and October 31, 1992 and included all 64 consecutive patients who underwent laparotomy with either a colonic or an ileal resection.

Sander R. Binderow; Stephen M. Cohen; Steven D. Wexner; Juan J. Nogueras

1994-01-01

173

Relation of anthropometric and dynamometric variables to serious postoperative complications  

Microsoft Academic Search

Prediction of serious postoperative complications by using standard anthropometric and biochemical nutritional variables was attempted in 225 patients admitted for major abdominal surgery. In 102 of the patients hand-grip dynamometry was also measured, and this proved the most sensitive test, predicting complications in 48 of the 55 patients (87%) who developed them (p < 0.001). Arm muscle circumference and forearm

A M Klidjian; K J Foster; R M Kammerling; A Cooper; S J Karran

1980-01-01

174

Acute postoperative delirium: Definitions, incidence, recognition, and interventions  

Microsoft Academic Search

Emergence excitement or delirium is a common postanesthesia complication. Often, the emergence excitement resolves quickly, and the patient's continued recovery is uneventful. Although the initial period of excitement may be short lived and resolve without long-term sequela, some patients may experience acute postoperative delirium, a phenomenon that is more difficult to assess and of potentially longer duration. Although patients are

Denise O'Brien

2002-01-01

175

Risk factors for postoperative delirium in vascular surgery  

Microsoft Academic Search

The aim of this study was to identify psychiatric and somatic risk factors associated with the development, severity and duration of postoperative delirium after vascular surgery. Forty-seven patients underwent aortic, carotid artery and peripheral artery surgery. Both, surgeon and psychiatrist, monitored patients preoperatively with daily follow up. Preoperative psychiatric assessment included standardized psychopathological scales for the detection of psychiatric symptoms

Frank Schneider; Hinrich Böhner; Ute Habel; Jasmin B Salloum; Anselm Stierstorfer; Thomas C. Hummel; Caeser Miller; Ralf Friedrichs; Eckhard E. Müller; Wilhelm Sandmann

2002-01-01

176

Postoperative delirium and melatonin levels in elderly patients  

Microsoft Academic Search

Background: Melatonin, a hormone produced in the pineal gland, is involved in circadian rhythms and the sleep-wake cycle. Postoperative delirium is encountered frequently in elderly patients after major surgery; whether changes in the pattern of melatonin secretion are associated is unclear.Methods: Plasma samples were obtained every 2 hours from 19 patients without delirium and 10 with delirium after major abdominal

Hidetaka Shigeta; Akihiro Yasui; Yuji Nimura; Nobuo Machida; Moto-o Kageyama; Masakazu Miura; Masafumi Menjo; Kyoji Ikeda

2001-01-01

177

Topical lidocaine patch 5% for acute postoperative pain control  

Microsoft Academic Search

A 39-year-old para 3 woman presented for elective caesarean section (lower segment caesarean section (LSCS)) for breech presentation. The patient had a strong history of atopy and anaphylaxis to paracetamol, codeine, penicillin and latex. The patient was asthmatic, triggered by aspirin. Epidural anaesthesia was unsuccessful and LSCS was carried out under spinal anaesthesia. Postoperatively the patient was unwilling to take

D Gilhooly; B McGarvey; H OMahony; T C OConnor

2011-01-01

178

Topical lidocaine patch 5% for acute postoperative pain control.  

PubMed

A 39-year-old para 3 woman presented for elective caesarean section (lower segment caesarean section (LSCS)) for breech presentation. The patient had a strong history of atopy and anaphylaxis to paracetamol, codeine, penicillin and latex. The patient was asthmatic, triggered by aspirin. Epidural anaesthesia was unsuccessful and LSCS was carried out under spinal anaesthesia. Postoperatively the patient was unwilling to take analgesic medication due to fear of an allergic reaction. Three 5% lidocaine patches were applied to the wound for postoperative analgesia. This reduced the patient's visual analogue scale pain score from 10/10 to 5/10 at rest and 10/10 to 7/10 with movement. Transcutaneous electrical nerve stimulation was added and this improved associated back pain, reducing the pain further to 2/10. This is the first description of lignocaine patch 5% for postoperative LSCS pain. It is suggested that this method of delivery of local anaesthetic, which is easy to apply and has minimal side effects, should be considered not as a sole agent but as part of a multimodal technique to address postoperative LSCS pain. PMID:22715181

Gilhooly, D; McGarvey, B; O'Mahony, H; O'Connor, T C

2011-01-01

179

ASA classification and perioperative variables as predictors of postoperative outcome  

Microsoft Academic Search

In a prospective study of 6301 surgical patients in a university hospital, we examined the strength of association between ASA physical status classi- fication and perioperative risk factors, and post- operative outcome, using both univariate analysis and calculation of the odds ratio of the risk of developing a postoperative complication by means of a logistic regression model. Univariate analysis showed

U. WOLTERS; T. WOLF; H. STÜTZER; T. SCHRÖDER

1996-01-01

180

Nutrition support of the postoperative cardiac surgery child.  

PubMed

There may be a correlation in critically ill children between the accuracy of estimated energy requirement and infection, mortality, and length of stay. Historically, energy needs were estimated using predictive equations with stress factor adjustments. The purpose of this review is to evaluate the evidence for indirect calorimetry, predictive equations, and other clinical indicators (ie, patient outcomes) to estimate energy requirements of the postoperative, critically ill, cardiac infant. Consistent with current guidelines, indirect calorimetry provides the best estimate of energy requirements for critically ill children. Predictive equations are unreliable, either over- or underestimate energy requirements, and do not take into account the metabolic changes that occur in the postoperative cardiac infant. To address the changing metabolic state throughout the course of illness, clinicians need to individualize recommendations by implementing frequent indirect calorimetry measurements at bedside. Actual energy delivery to the postoperative cardiac surgery child in the pediatric intensive care unit (PICU) can be further hindered by many procedural and patient barriers. The provision of appropriate caloric requirements may help clinicians correct the metabolic state and promote recovery and anabolism. Therefore, optimizing nutrition intake of the postoperative, cardiac surgical child requires a paradigm shift toward individualized nutrition prescription, in the context of a PICU-specific feeding algorithm. PMID:23921299

Leong, Amanda Y; Field, Catherine J; Larsen, Bodil M

2013-10-01

181

Postoperative wound infection in 32,000 clean operations.  

PubMed

The frequencies of postoperative wound infection in clean operations have been registered at a county hospital (Falun, Sweden) during a 15-year period (1958-1972). A total of 64,000 operations were done and about 32,000 of these have been registered as clean operations. In 1968 the wards were transformed from 12-bed rooms to 5-bed rooms and the operating theatres were rebuilt. All premises were equipped with high pressure air ventilation including lock system. Furthermore, a new intensive care unit and a new awakening unit were built. The overall postoperative wound infection (sepsis) rate during this 15-year period was 1.7 percent. The infection rates in the 5-year period before and in the 5-year period after opening of the new buildings were the same: 1.6 percent. After adding postoperative infections (sepsis) and postoperative inflammatory reactions, the total rates were almost the same: 4.1 percent before and 4.2 percent after. A slight rise in staphylococcal infections has been registered. This rise might suggest that the expected positive effects of the new buildings have been counteracted by other exogenous and endogenous factors. Some of these factors have been discussed (rise in mean age etc.). On the basis of this investigation it seems likely that the management (in all respects) of the surgical patients is still of the greatest importance, regardless of fine new buildings. PMID:1007788

Leissner, K H

1976-01-01

182

[Hyponatremia and convulsions in the postoperative period in children].  

PubMed

Four children undergoing surgery presented with seizures and hyponatremia 12 hours after anesthesia. One child died with cerebral oedema, the others recovered. The respective roles of hypo-osmolar perfusions and ADH secretion are discussed. Ionogram before surgery, supervision of weight and diuresis and correct fluid management should prevent these postoperative complications. PMID:3060040

Teyssier, G; Rayet, I; David, T; Serio, A; Damon, G; Freycon, F

1988-01-01

183

[Ultrasonographic diagnosis and characteristic of postoperative accumulations of a liquid].  

PubMed

Ultrasonographic semiotics of extraorgan localized postoperative accumulations of a liquid occurring after performance of interventions on a liver was studied up. There was established the dependence of their localization on the operation kind. The differential diagnosis algorithm of some pathologic conditions (haematoma, biloma, seroma) was elaborated. PMID:21090358

Moshkivs'ky?, H Iu

2010-09-01

184

Pancoast tumors: improved survival with preoperative and postoperative radiotherapy  

Microsoft Academic Search

Long-term survival after treatment of Pancoast tumors has been limited in most series to those patients without positive lymph nodes or residual tumor. In our series of 18 consecutive patients treated with preoperative irradiation and resection, 14 underwent supplemental postoperative radiotherapy because of positive lymph nodes, tumor at the resection margin, or both. No hospital deaths occurred. Eight patients subsequently

David M. Shahian; Wilford B. Neptune; F. Henry Ellis Jr.

1987-01-01

185

How to read a postoperative total hip replacement radiograph  

Microsoft Academic Search

In 2006 over 55 000 primary total hip replacements were implanted in the UK. A crucial aspect of follow-up for these patients is the assessment of the postoperative radiograph. Information gained from the initial radiograph includes assessment of the quality of implantation and hence the likelihood of long term success. Follow-up radiographs can be assessed for signs of component failure.

Tim J McBride; Divya Prakash

2010-01-01

186

Is EGFR expression altered following postoperative chemotherapy for colorectal adenocarcinoma?  

Microsoft Academic Search

BACKGROUND: There is immunohistochemical evidence to suggest that expression of epidermal growth factor receptor (EGFR) in primary colorectal adenocarcinoma predicts its expression in recurrent disease. This study investigates whether postoperative chemotherapy affects the degree of concordance between EGFR statuses of the two tumors. METHODS: Thirty-three patients were identified from the files of Sunnybrook Health Sciences Center from July 1994 to

Mahmoud A Khalifa; Corwyn H Rowsell; Rebecca Gladdy; Yoo-Joung Ko; Sherif Hanna; Andy Smith; Calvin Law

2006-01-01

187

Continuous narcotic infusions for relief of postoperative pain  

Microsoft Academic Search

Relief of acute pain after surgery or trauma is still inadequate in many centres, most patients being treated with intermittent intramuscular injections of narcotic analgesics. Over the past three years continuous intravenous narcotic infusions have been used at this hospital to treat postoperative pain; recently a system has been devised whereby an hourly dose is given and the dispenser recharged

J J Church

1979-01-01

188

SMI 2006: N 58 Patient safety in operative and postoperative  

E-print Network

33 SMI 2006: Nº 58 Summary Patient safety in operative and postoperative structures is closely hours or resource allocation are designed to improve patient safety. However, it is necessary to measure linked to adequate resource allocation and patient flow organisation. New policies concerning working

Bierlaire, Michel

189

Sonderdruck aus: Wissensideale und Wissenskulturen  

E-print Network

of Knowledge in Early Modem Europe Herausgegeben von Wolfgang Detel und Claus Zittel ISBN 3-05-003713-X of Sunspots' Troubled dichotomies Historians of early modem science and medicine have distinguished two kinds and identifiine imaees finds sumort both in stan-- , u - .. dard histories of early modem printed illustrations

190

Programmierung und ActionScript  

Microsoft Academic Search

\\u000a Mittlerweile haben Sie Ihren Kaffee aus dem vorhergehenden Kapitel genossen und stellen sich die Frage, ob man denn tatsächlich\\u000a jedes Mal, wenn es einen nach Kaffee gelüstet, programmieren muss. Sicher nicht, dennoch sprechen zahlreiche Gründe für die\\u000a Programmierung (zumindest in der Flash-Entwicklung).

Arno Kohl

191

Pseudarthrosen an Femur und Tibia  

Microsoft Academic Search

Pseudarthrosen stellen eine der wesentlichen Komplikationen nach Osteosynthesen an den unteren Gliedmaßen dar. Neben initialer ausgeprägter Weichteilschädigung und patientenbedingten Faktoren können suboptimale technische Lösungen bei der Frakturversorgung auslösend sein. Vor der Indikation zur operativen Therapie sollte eine genaue Problemanalyse erfolgen. In ausgewählten Fällen kann auch eine nichtoperative Behandlung zum Ziel führen. Die Revisionsoperation einer Pseudarthrose im diaphysären Bereich eines langen

O. Gonschorek; T. Mückley; O. Trapp; C. Josten

2005-01-01

192

Factors Associated with Postoperative Pain in Endodontic Therapy  

PubMed Central

Objective: To assess postoperative pain in endodontic therapy and its association with clinical factors such as gender, age, tooth type, pulpal diagnosis, and preoperative pain, length of obturation and sealer extrusion. Study Design: Cross-Sectional study. Place and Duration of Study: Dental section of the Aga khan university hospital, Karachi, Pakistan from January to December 2009. Methodology: One hundred and forty patients (140) requiring endodontic therapy for molar and premolar teeth were included in this study. Local Anesthesia (2% Lidocain with 1:80,000 Epinephrine) was administered. The tooth was isolated with rubber dam. Access cavity was prepared with the help of round carbide No. 2 bur. Canal preparation was completed using crown-down technique. Access was sealed with sterile dry cotton pallet and restored temporarily with double layer of Glass ionomer cement and Cavit. After one week patients were recalled and access was re-opened, obturation was done using cold lateral condensation technique. Ca(OH)2 based sealer was used. Postoperative radiographs were taken. Patients were recalled after 24 hours and postobturation pain was recorded using Visual analogue scale (VAS).Data was obtained on a structured Performa. ?2 test was used for statistical analysis. Results: Pain was present in 42.9% of patients. Females more frequently experienced pain (65%) than males (35%). Preoperative pain was found to be significantly associated with postoperative pain (p value < 0.001). Obturation length was not found to be significantly associated with postoperative pain (p value 1.0). Sealer extrusion was not found to be significantly associated with postoperative (P value 0.547). PMID:25598754

Sadaf, Durre; Ahmad, Muhammad Zubair

2014-01-01

193

Predictors of Postoperative Complications After Trimodality Therapy for Esophageal Cancer  

PubMed Central

Purpose While trimodality therapy for esophageal cancer has improved patient outcomes, surgical complication rates remain high. The goal of this study was to identify modifiable factors associated with postoperative complications after neoadjuvant chemoradiation. Methods and Materials From 1998 to 2011, 444 patients were treated at our institution with surgical resection after chemoradiation. Postoperative (pulmonary, gastrointestinal [GI], cardiac, wound healing) complications were recorded up to 30 days postoperatively. Kruskal-Wallis tests and ?2 or Fisher exact tests were used to assess associations between continuous and categorical variables. Multivariate logistic regression tested the association between perioperative complications and patient or treatment factors that were significant on univariate analysis. Results The most frequent postoperative complications after trimodality therapy were pulmonary (25%) and GI (23%). Lung capacity and the type of radiation modality used were independent predictors of pulmonary and GI complications. After adjusting for confounding factors, pulmonary and GI complications were increased in patients treated with 3-dimensional conformal radiation therapy (3D-CRT) versus intensity modulated radiation therapy (IMRT; odds ratio [OR], 2.018; 95% confidence interval [CI], 1.104–3.688; OR, 1.704; 95% CI, 1.03–2.82, respectively) and for patients treated with 3D-CRT versus proton beam therapy (PBT; OR, 3.154; 95% CI, 1.365–7.289; OR, 1.55; 95% CI, 0.78–3.08, respectively). Mean lung radiation dose (MLD) was strongly associated with pulmonary complications, and the differences in toxicities seen for the radiation modalities could be fully accounted for by the MLD delivered by each of the modalities. Conclusions The radiation modality used can be a strong mitigating factor of postoperative complications after neoadjuvant chemoradiation. PMID:23845841

Wang, Jingya; Wei, Caimiao; Tucker, Susan L.; Myles, Bevan; Palmer, Matthew; Hofstetter, Wayne L.; Swisher, Stephen G.; Ajani, Jaffer A.; Cox, James D.; Komaki, Ritsuko; Liao, Zhongxing; Lin, Steven H.

2013-01-01

194

[Balloon dilatation of postoperative and congenital aortic isthmus stenoses].  

PubMed

From July 1987 to December 1992, 52 patients underwent balloon-angioplasty of aortic coarctation at three units of pediatric cardiology in Austria (Graz = 35 patients, Innsbruck = 15 patients, and Vienna = 2 patients). 35 patients had postoperative and 17 had native coarctation. Mean age at intervention was 7 10/12 years with 2 patients under 1 year and 5 patients over 18 years old. The mean relation balloon diameter-coarctation diameter was 2.6 +/- 0.9. The blood pressure gradient between upper and lower extremities decreased from a mean of 44 +/- 16 mm Hg to 15 +/- 13 mm Hg (p < 0.0001). The diameter of the stenosed segment was increased from 5 +/- 3 mm to 8.5 +/- 3.5 mm (p < 0.0001). Native coarctation showed a significantly better result in respect to decrease of the gradient (36 +/- 12 mm Hg) than did postoperative coarctations (25 +/- 19 mm Hg) (p < 0.03). 13 patients did not respond adequately to angioplasty. 10 patients out of this group had tubular narrowings and belonged to the group of postoperative coarctations, whereas localized stenoses in native coarctations gave the best results. Localized wall irregularities were found in 4 patients with native coarctation. Balloon angioplasty of postoperative and native coarctations in childhood and adolescence is a secure and effective means of treatment and should be considered as therapy of first choice. The best results can be found in the group of the circumscript type of stenoses in native coarctation, whereas long and tubular stenoses in the group of postoperative coarctations give less satisfying results. PMID:7846934

Beitzke, A; Stein, J I; Haidvogl, M; Pilhatsch, A; Suppan, C; Hammerer, I; Fink, C; Fritz, M; Schlemmer, M; Wimmer, M

1994-12-01

195

Aspirin and Postoperative Bleeding After Coronary Artery Bypass Grafting  

PubMed Central

Objective To evaluate the relationship between aspirin ingestion and postoperative bleeding complications, and to test the hypothesis that there is a subset of patients who are aspirin hyperresponders with a proclivity toward platelet dysfunction. Summary Background Data Despite numerous retrospective and prospective analyses, it is still controversial as to whether aspirin ingestion before coronary artery bypass grafting (CABG) is associated with significant postoperative bleeding. Methods Between January 1995 and December 1999, the records of 2,606 consecutive patients undergoing CABG were reviewed to identify patients with a history of aspirin ingestion up until the time of surgery. Aspirin ingestion was correlated with postoperative blood transfusion using multivariate analysis. In a subset of preoperative aspirin users (n = 40), bleeding times were measured before and after aspirin use. Flow cytometry was performed in another cohort of patients with known heart disease (n = 30) to determine the effect of aspirin on platelet surface receptors. Results During the 5-year study period, 63% of the CABG patients were identified as aspirin users. Among these, 23.1% required blood transfusions compared with 19% for the nonusers. Non-red blood cell transfusions were more common in aspirin users, as was reexploration for bleeding. Stratification of these results according to the frequency of aspirin use showed that aspirin is an independent multivariate predictor of postoperative blood transfusion only in high-risk patients. In the prospective studies, aspirin treatment resulted in a significant increase in the template bleeding time, an increase in platelet PAR-1 thrombin receptor activity, and a decrease in the binding of platelets to monocytes. Conclusions The findings support the hypothesis that aspirin is associated with a greater likelihood of postoperative bleeding. A platelet function testing algorithm that combines preoperative risk factor assessment, template bleeding times, and flow cytometry may allow the identification of aspirin hyperresponders who are at increased risk for bleeding. PMID:12035038

Ferraris, Victor A.; Ferraris, Suellen P.; Joseph, Oji; Wehner, Paulette; Mentzer, Robert M.

2002-01-01

196

Postoperative cognitive dysfunction: Involvement of neuroinflammation and neuronal functioning.  

PubMed

Postoperative cognitive dysfunction (POCD) has been hypothesized to be mediated by surgery-induced inflammatory processes, which may influence neuronal functioning either directly or through modulation of intraneuronal pathways, such as the brain derived neurotrophic factor (BDNF) mediated pathway. To study the time course of post-surgical (neuro)inflammation, changes in the BDNF-pathway and POCD, we subjected 3months old male Wistar rats to abdominal surgery and implanted a jugular vein catheter for timed blood sampling. Cognition, affective behavior and markers for (neuro)inflammation, BDNF and neurogenesis were assessed at 1, 2 and 3weeks following surgery. Rats displayed changes in exploratory activity shortly after surgery, associated with postoperatively elevated IL-6 plasma levels. Spatial learning and memory were temporarily impaired in the first 2weeks following surgery, whereas non-spatial cognitive functions seemed unaffected. Analysis of brain tissue revealed increased neuroinflammation (IL-1B and microgliosis) 7days following surgery, decreased BDNF levels on postoperative day 14 and 21, and decreased neurogenesis until at least 21days following surgery. These findings indicate that in young adult rats only spatial learning and memory is affected by surgery, suggesting hippocampal dependent cognition is especially vulnerable to surgery-induced impairment. The observed differences in time course following surgery and relation to plasma IL-6 suggest cognitive dysfunction and mood changes comprise distinct features of postoperative behavioral impairment. The postoperative changes in neuroinflammation, BDNF and neurogenesis may represent aspects of the underlying mechanism for POCD. Future research should be aimed to elucidate how these players interact. PMID:24517920

Hovens, Iris B; Schoemaker, Regien G; van der Zee, Eddy A; Absalom, Anthony R; Heineman, Erik; van Leeuwen, Barbara L

2014-05-01

197

Pohls Einführung in die Physik: Elektrizitätslehre und Optik.  

NASA Astrophysics Data System (ADS)

Der "Pohl", jahrzehntelang das klassische Lehrbuch der Experimentalphysik, erscheint jetzt in einer überarbeiteten und mit Kommentaren und Videos ausgestatteten neuen Auflage. Aufgeteilt in 2 Bände, erscheint jetzt Band 2: Elektrizitätslehre und Optik, Band 1 zur Mechanik, Akustik und Wärmelehre ist bereits im Frühjahr 2004 erschienen. Die klare und einprägsame, stets vom Experiment ausgehende Darstellung der physikalischen Grundlagen hat bis heute nichts von ihrer Frische und Aktualität eingebüßt.

Lüders, Klaus; Pohl, Robert Otto

198

Die Fortschritte der Naturwissenschaften im 17. und 18. Jahrhundert  

Microsoft Academic Search

\\u000a Im 17. und 18. Jahrhundert wurden wichtige Voraussetzungen für die Entwicklung der Biologie zu einer exakten Naturwissenschaft\\u000a im 19. Jahrhundert geschaffen. Die Natur wurde neu entdeckt und ihre Bestandteile genauer untersucht. Durch Reisen in fremde\\u000a Länder und Kontinente wurde eine große Vielfalt neuer Pflanzen und Tiere entdeckt und beschrieben. Die Anatomie des Menschen,\\u000a aber auch die von Tieren und Pflanzen,

Gerhart Drews

199

UniReport Satzungen und Ordnungen vom 17. Oktober 2011 1 Ordnung des Fachbereichs Psychologie und Sportwissenschaften an der Johann  

E-print Network

Sports Medical Training/Clinical Exercise Physiology (Sportmedizinisches Training und Exercise Physiology" (,,Sportmedizinisches Training und Leistungsphy- siologie") mit dem Abschluss ,,Master Exercise Physiology (Sportmedizinisches Training und Leistungsphysiologie) Abkürzungsverzeichnis: CP Credit

200

Burnout Prävention für Betreuerinnen und Betreuer autistisch behinderter Menschen.  

E-print Network

??Betreuer autistisch behinderter Menschen sind auf Grund der Eigenheiten ihrer Klienten spezifischen Herausforderungen und hohen Belastungen ausgesetzt. Diese Herausforderungen und Belastungen können zu einem erhöhten… (more)

Schörghuber, Oliver

2009-01-01

201

Ubiquitous Computing - Eine Herausforderung für Datenschutz und Sicherheit  

Microsoft Academic Search

Kurzfassung. Das noch junge Forschungsgebiet des Ubiquitous Computing beschäftigt sich damit, kleinste Computerprozessoren und mikroelektronische Sensoren in die Umwelt und in Alltagsgegenstän- de zu integrieren, um diese \\

Friedemann Mattern

202

Studien zu Epidemiologie und Bekämpfung der Stallkokzidiose bei Sauglämmern.  

E-print Network

??Ziel der vorliegenden Arbeit war es, die Stallkokzidiose bei Sauglämmern in drei verschiedenen Lämmermastbetrieben anhand der klinischen Ausprägung und parasitologischer Parameter zu charakterisieren und zu… (more)

Dittmar, Katja

2010-01-01

203

ber die Grndung des ,,Helmholtz-Institutes Mainz" Struktur, Symmetrie und Stabilitt von Materie und Antimaterie  

E-print Network

Memorandum über die Gründung des ,,Helmholtz-Institutes Mainz" Struktur, Symmetrie und Stabilität ,,HelmholtzInstitutes Mainz" Struktur, Symmetrie und Stabilität von Materie und Antimaterie Der Deutsche Bundestag hat die Gründung gemeinsamer Institute der Helmholtz- Gemeinschaft mit Universitäten in solchen

Hanke-Bourgeois, Martin

204

Der Aufschluß von Radiumsulfat mit Ionenaustauschharzen und die Abtrennung des Radiums D und Poloniums vom Radium  

Microsoft Academic Search

Es wird ein Verfahren beschrieben, welches die Abtrennung von Ra D, Ra E und Po vom schwerlöslichen Radium-Bariumsulfat gestattet. Po wird durch Auflösen des Sulfats in konz. Schwefelsäure und Wiederausfällen desselben durch Zugabe von Wasser zu 90–100% in Lösung gehalten. Das Sulfat kann durch Rühren mit einem Gemisch aus Kationen- und Anionenaustauscher aufgeschlossen werden. Die Abtrennung des Radiums D von

W. Dedek

1960-01-01

205

Brasilien und die Amerikas: Lateinamerika und die USA als Bezugspunkte der brasilianischen Außenpolitik  

Microsoft Academic Search

1. Einleitung Jede Außenpolitik basiert auf Selbst- und Fremdbildern, d.h. auf Vor- stellungen von der eigenen Identität und dem Platz, den das eigene Land in der Welt einnimmt (oder einnehmen sollte), aber auch auf Bildern, die sich die außenpolitischen Entscheidungsträger von den Nachbarländern und vom Zustand des internationalen Systems insge- samt machen. Die der brasilianischen Außenpolitik zu Grunde liegen- den

Peter Birle

206

Funde bemerkenswerter Gefäßpflanzenarten in den Enns- und Steyrtaler Kalk und Flyschvoralpen (Oberösterreich)  

Microsoft Academic Search

Floristic records of remarkable vascular plant species in the Enns- und Steyrtaler Kalk- und Flyschvoralpen (Eastern Alps of Upper Austria) New records of 63 rare vascular plant species are presented from the northeastern part of the Upper Austrian Alps (Ennstaler Flysch- und Kalkvoralpen, Enns- and Steyr- valley). The new localities are discussed with respect to relevant literature and the regional

F. ESSL

207

Struktur und Kinematik der edge-on Galaxien NGC 4700, NGC 7090 und  

E-print Network

Struktur und Kinematik der edge-on Galaxien NGC 4700, NGC 7090 und NGC 7462 Diplomarbeit im Fach Geschwindigkeitsfeld und die Dispersion . . . . . . . . . . . . 48 6.2 NGC 7090 Tilted-Ring-Modellierungen f¨ur NGC 7090 . . . . . . 67 7.5.1 ROTCUR

Józsa, Gyula I. G.

208

Die Logik der Grenzerhaltung und die Logik der Grenzüberschreitungen: Niklas Luhmann und die Kulturtheorien  

Microsoft Academic Search

Die intellektuelle Entwicklung der westlichen Sozial-, Kultur- und Gesellschaftstheorien befindet sich gegenwärtig auf einem Zwischenplateau: Eine Phase der Theorieentwicklung, die in den 1960er Jahren begann, kommt seit den 1990er Jahren allmählich an ihr Ende. Anfangs umstrittene Theoretiker sind mittlerweile klassisch geworden und zum Gegenstand umfänglicher Interpretationsaktivitäten avanciert; eine ganze Generation von Sozial- und Gesellschaftstheoretikern verläßt derweil die Bühne, was im

Andreas Reckwitz

209

Bestimmung der Körperlänge und des Lebensalters menschlicher Feten auf Grund der ersten Hand und ersten Fußwurzelknochenmaße, sowie der Größe des Atlas und des Epistropheus-Wirbelbogens  

Microsoft Academic Search

Es wurden die Größenmaße des I. Hand- und des I. Fußwurzelknochens und des Atlas- und Epistropheuswirbelbogens von 138 totgeborenen oder wenige Stunden nach der Geburt gestorbenen menschlichen Feten — 71 Knaben und 67 Mädchen mit einer Länge von 9–55 cm — bestimmt.

I. Gy. Fazekas; F. Kósa

1967-01-01

210

Massage as adjuvant therapy in the management of acute postoperative pain: a preliminary study in men  

Microsoft Academic Search

BackgroundOpioid analgesia alone may not fully relieve all aspects of acute postoperative pain. Complementary medicine techniques used as adjuvant therapies have the potential to improve pain management and palliate postoperative distress.

Marcia M Piotrowski; Cynthia Paterson; Allison Mitchinson; Hyungjin Myra Kim; Marvin Kirsh; Daniel B Hinshaw

2003-01-01

211

Preoperative anemia increases postoperative morbidity in elective cranial neurosurgery  

PubMed Central

Background: Preoperative anemia may affect postoperative mortality and morbidity following elective cranial operations. Methods: The American College of Surgeons National Surgical Quality Improvement Program (NSQIP) database was used to identify elective cranial neurosurgical cases (2006-2012). Morbidity was defined as wound infection, systemic infection, cardiac, respiratory, renal, neurologic, and thromboembolic events, and unplanned returns to the operating room. For 30-day postoperative mortality and morbidity, adjusted odds ratios (ORs) were estimated with multivariable logistic regression. Results: Of 8015 patients who underwent elective cranial neurosurgery, 1710 patients (21.4%) were anemic. Anemic patients had an increased 30-day mortality of 4.1% versus 1.3% in non-anemic patients (P < 0.001) and an increased 30-day morbidity rate of 25.9% versus 14.14% in non-anemic patients (P < 0.001). The 30-day morbidity rates for all patients undergoing cranial procedures were stratified by diagnosis: 26.5% aneurysm, 24.7% sellar tumor, 19.7% extra-axial tumor, 14.8% intra-axial tumor, 14.4% arteriovenous malformation, and 5.6% pain. Following multivariable regression, the 30-day mortality in anemic patients was threefold higher than in non-anemic patients (4.1% vs 1.3%; OR = 2.77; 95% CI: 1.65-4.66). The odds of postoperative morbidity in anemic patients were significantly higher than in non-anemic patients (OR = 1.29; 95% CI: 1.03-1.61). There was a significant difference in postoperative morbidity event odds with a hematocrit level above (OR = 1.07; 95% CI: 0.78-1.48) and below (OR = 2.30; 95% CI: 1.55-3.42) 33% [hemoglobin (Hgb) 11 g/dl]. Conclusions: Preoperative anemia in elective cranial neurosurgery was independently associated with an increased risk of 30-day postoperative mortality and morbidity when compared to non-anemic patients. A hematocrit level below 33% (Hgb 11 g/dl) was associated with a significant increase in postoperative morbidity. PMID:25422784

Bydon, Mohamad; Abt, Nicholas B.; Macki, Mohamed; Brem, Henry; Huang, Judy; Bydon, Ali; Tamargo, Rafael J.

2014-01-01

212

Die Scleranthus -Arten Österreichs und seiner Nachbarländer  

Microsoft Academic Search

Zusammenfassung 1.In Österreich kommen vierScleranthus-Arten vor:S. perennis, S. annuus, S. polycarpos undS. collinus; außerdem der BastardS. annuus ×S. perennis. Synonymie, Morphologie, Ökologie dieser Sippen werden dargestellt, auf offene Fragen wird hingewiesen.2.S. alpestrisHayek ist keine besondere Sippe der Ostalpen, sondern mitS. polycarpos identisch.3.Die in Österreich vorkommenden Arten finden sich auch in (den Nachbarstaaten) Deutschland, der Tschechoslowakei, Ungarn, Jugoslawien, Italien und der

Wilhelm Rössler

1955-01-01

213

Brasiliens zivilgesellschaftliche Organisationen und die Regierung Lula  

Microsoft Academic Search

Schon theoretisch sind die Beziehungen zwischen Nichtregierungsorganisationen (NRO) und politischen Parteien kompliziert genug,\\u000a ja widersprüchlich - zielen Erstere doch auf die Vertretung sozialer, kultureller, umweit- und geschlechterbezogener Forderungen\\u000a ab, während Letztere auf die Schaffung von Wähler- und Parlamentsmehrheiten aus sind, was zwangsläufig auch Kompromisse mit\\u000a anderen Interessenträgern statt nur mit der eigenen sozialen Basis einschließt. In der Praxis können sich

Gilberto Calcagnotto

214

Simulation und Emulation im Internet der Dinge  

Microsoft Academic Search

\\u000a Die Simulation sowie die Emulation stellen im Kontext des Internet der Dinge Instrumente von hoher Bedeutung dar. Der Artikel\\u000a gibt zunächst mit der Begriffsdefinition und der Beschreibung von Anwendungen eine Einführung in die Themenfelder der Simulation\\u000a und der Emulation. Anschließend wird auf den Aufbau und die Eigenschaften von existierenden Materialflusssimulatoren eingegangen.\\u000a Der Hauptteil des Artikels beschäftigt sich mit Möglichkeiten des

Damian Daniluk; Razvan Chisu

215

Homöopathie bei Kinderwunsch und im Klimakterium  

Microsoft Academic Search

Zusammenfassung  Die Homöopathie ist in Deutschland eine der 3 im Sozialgesetzbuch V verankerten besonderen Therapierichtungen. Festlegung\\u000a von Ziel und Inhalt sowie die Anerkennung der absolvierten Zusatzweiterbildung Homöopathie erfolgt durch die zuständigen Landesärztekammern.\\u000a Die klassische Homöopathie mit dem erforderlichen ausführlichen Erstgespräch und anschließender Repertorisation wird von der\\u000a Bevölkerung und den anwendenden Ärzten sehr geschätzt. Homöopathische Komplexmittel werden auch von vielen Ärzten ohne Zusatzweiterbildung

A. Glenz; I. Resch; C. von Hagens

2008-01-01

216

Das DLR: Hoch hinaus und bodenständig  

NASA Astrophysics Data System (ADS)

Die "irdische" Komponente des DLR, die wenig oder keine Verbindungen zur Luft- und Raumfahrt aufweist, bietet aber durchaus ebenso Beschäftigungsmöglichkeiten für unsere Zunft, wie das Beispiel von Dipl.-Geogr. Annette Bona unterstreicht, die als Projektmanagerin in der Organisationseinheit "Innovationsmanagement und Technologiemarketing" am Kölner Standort beschäftigt ist. Mit ihr unterhielt sich Jörg Franzen M. A. über die weniger bekannten, bodengebundenen Tätigkeiten des DLR und ihren spezifischen Anteil daran.

Bona, Annette

2002-03-01

217

Prior Conditions Influencing Nurses' Decisions to Adopt Evidence-Based Postoperative Pain Assessment Practices  

Microsoft Academic Search

Over the past 30 years, postoperative pain relief has been shown to be inadequate. To provide optimal postoperative pain relief, it is imperative for nurses to use evidence-based postoperative pain assessment practices. This correlational descriptive study was conducted to identify factors, termed prior conditions, that influenced nurses' decisions to adopt three evidence-based postoperative pain assessment practices. A convenience sample of nurses

Cathy L. Carlson

2010-01-01

218

Vergleichende Untersuchungen zur Adhärenz und Mauspathogenität von Yersinia-Adhäsin (YadA)-Varianten verschiedener Yersinia-Arten und -Serotypen.  

E-print Network

??Zusammenfassung Die enteropathogenen Yersinia-Arten Y. enterocolitica und Y. pseudotuberculosis verursachen neben Enteritiden und Enterokolitiden auch extraintestinale Erkrankungen wie reaktive Arthritis oder Erythema nodosum. In ihrem… (more)

Untiet, Sarah

2013-01-01

219

Geschichte des Widerstandes in Film und Fernsehen.  

E-print Network

??In der Diplomarbeit „Geschichte des Widerstandes in Film und Fernsehen“ wird die unterschiedliche Darstellungsweise des Stauffenberg-Attentats auf den „Führer“ Adolf Hitler vom 20. Juli 1944… (more)

Bauer, Marlies

2010-01-01

220

Kleptochemie und Kleptoplastie in Opisthobranchia (Mollusca: Gastropoda).  

E-print Network

??Zwei mögliche Schlüsselmerkmale (Kleptoplastie und Kleptochemie) der Opisthobranchia werden untersucht. Im Fokus steht dabei die Nutzung von Naturprodukten als chemische Verteidigungsstrategie. Einige dieser Stoffe stammen… (more)

Grzymbowski, Yvonne

2008-01-01

221

Zur Pharmakologie von Ephedrin und Isalon  

Microsoft Academic Search

Zusammenfassung An der intakten und dekapitierten Katze steht die bronchiospasmolytische Wirkung des Isalons im. Vordergrund. Die tierexperimentellen Befunde stimmen demnach mit der klinischen Erfahrung überein.

Hans Rietschel

1935-01-01

222

Brief Postoperative Delirium in Hip Fracture Patients Affects Functional Outcome at Three Months  

Microsoft Academic Search

It is unclear how brief postoperative delirium (DEL) affects functional outcomes. In this study, we sought to determine if patients with brief postoper- ative DEL (6-wk duration) have different living situations when compared with non-DEL patients after hip fracture repair. In a prospective study, patients admitted to the geriatric hip fracture ser- vice were assessed every postoperative day for the

Khwaja Zakriya; Frederick E. Sieber; Colleen Christmas; James F. Wenz; Shawn Franckowiak

2004-01-01

223

[Postoperative dissection of the vertebral artery in two steps].  

PubMed

The diagnosis of perioperative vertebral artery dissection can be difficult because of non-specific clinical signs. We report a case revealed by a tegmento-thalamic stroke after an abdominal second surgical look. The interest of this observation is related to a particular evolution in two steps separated by a 2-month-interval and an intercurrent cervical manipulation. After the second anesthesia, neck pain associated with a third cranial nerve palsy and a supranuclear ophtalmoplegia revealed a tegmento-thalamic ischemic stroke due to vertebral artery dissection. We discuss here the different factors possibly involved in the pathophysiology of postoperative vertebral artery dissection: positioning, cervical manipulation, subclavian central venous access and cisplatin toxicity. Vertebral artery dissection should be discussed in case of postoperative neck pain, especially with non-typical symptomatology. PMID:25447780

Bien, J-Y; Morel, J; Demasles, S; Abboud, K; Molliex, S

2014-12-01

224

Predicting postoperative arterial pressure in renovascular hypertensive patients.  

PubMed

The authors have developed a method for forecasting the degree of the hypotensive effect of surgery for renovascular hypertension. Fifteen digital parameters were determined in 36 patients with unilateral lesions of the renal arteries by the following methods of preoperative examination: the establishment of the duration of hypertension, radio-isotope renography, determination of renin activity in the peripheral and renovascular (venous) blood, rheonephrography. The obtained set of characteristics was used for the prediction of postoperative arterial pressure values by means of one of the methods of mathematical statistics, the regression analysis in an "SM-4" electronic computer according to a specially created multivariate regression program in the "Fortran-4" language. The high accuracy of predicting the arterial pressure by this method was confirmed by clinical trials. Forecasting postoperative arterial pressure by this method allows us to substantiate with a high degree of fidelity the advisability of reconstructive surgery and opens up realistic prospects for improving its results. PMID:2600119

Krotovsky, G S; Ellansky, M M; Turpitko, S A; Mamedov, D M

1989-01-01

225

Postoperative cognitive dysfunction: current developments in mechanism and prevention.  

PubMed

Postoperative cognitive dysfunction (POCD) is a subtle disorder of thought processes, which may influence isolated domains of cognition and has a significant impact on patient health. The reported incidence of POCD varies enormously due to lack of formal criteria for the assessment and diagnosis of POCD. The significant risk factors of developing POCD mainly include larger and more invasive operations, duration of anesthesia, advanced age, history of alcohol abuse, use of anticholinergic medications, and other factors. The release of cytokines due to the systemic stress response caused by anesthesia and surgical procedures might induce the changes of brain function and be involved in the development of postoperative cognitive dysfunction. The strategies for management of POCD should be a multimodal approach involving close cooperation between the anesthesiologist, surgeon, geriatricians, and family members to promote early rehabilitation and avoid loss of independence in these patients. PMID:25306127

Wang, Wei; Wang, Yan; Wu, Haibo; Lei, Liming; Xu, Shiqin; Shen, Xiaofeng; Guo, Xirong; Shen, Rong; Xia, Xiaoqiong; Liu, Yusheng; Wang, Fuzhou

2014-01-01

226

Probiotics for the treatment of postoperative complications following intestinal surgery.  

PubMed

Probiotics are living micro-organisms that belong to the normal enteric flora and exert a beneficial effect on health and well-being. The rationale for the therapeutic use of probiotics in pouchitis (the most frequent long-term complication following pouch surgery for ulcerative colitis) and postoperative recurrence in Crohn's disease is based on convincing evidence suggesting a crucial role for the endogenous intestinal microflora in the pathogenesis of these conditions. Positive results have been obtained with the administration of highly concentrated probiotic preparations in preventing the onset and relapses of pouchitis. Further controlled studies are needed to establish the efficacy of probiotics in the prophylaxis of postoperative recurrences of Crohn's disease and in the treatment of mild pouchitis. PMID:14507591

Gionchetti, Paolo; Amadini, Cristina; Rizzello, Fernando; Venturi, Alessandro; Poggioli, Gilberto; Campieri, Massimo

2003-10-01

227

Lung transplantation. Part II. Postoperative management and results.  

PubMed Central

In part I of this 2-part article on lung transplantation (Western Journal of Medicine 1996; 165:355-363), we reviewed the current indications and operative techniques of the procedure. In part II, we describe the postoperative management and results of lung transplantation. We also discuss current controversies, such as the use of marginal donors, living-related transplants, marginal recipients, and single-versus double-lung transplantation for emphysema or pulmonary hypertension. PMID:9074338

Wood, D E; Raghu, G

1997-01-01

228

[Subsyndromal delirium - Experiences from the psychiatry - expectations for postoperative management].  

PubMed

The phenomenon of delirium is well known since over 100 years. The anesthesiology has recognized that early detection and therapy results in significant improvement of postoperative clinical state of health of the patients. In the following article it will be discussed that it could be profitable to make a further step: threatening the subsyndromal delirium. Because there are only few experiences in anesthesiology, this thesis will be substantiated by datas from psychiatry. PMID:25137201

Brinkers, Michael; Pfau, Giselher; Gerth, Nico; Hachenberg, Thomas

2014-07-01

229

Caudal epidural buprenorphine for postoperative pain relief in children  

Microsoft Academic Search

Postoperative pain relief by caudal epidural buprenorphine, a highly lipid-soluble, semisynthetic derivative of thebaine, has not been reported in children. Over a period of 1 year, 58 children undergoing various surgical procedures were given 3 g\\/kg epidural buprenorphine via the caudal route. No serious side effects were encountered; on the contrary, the excellent and long-lasting pain relief (about 7 days)

A. N. Gangopadhyay; P. Bhattacharya; A. Sinhal; A. Digar; S. C. Gopall; G. D. Singhall

1992-01-01

230

Postoperative radiotherapy in salivary ductal carcinoma: a single institution experience  

PubMed Central

Purpose We reviewed treatment outcomes and prognostic factors for patients with salivary ductal carcinoma (SDC) treated with surgery and postoperative radiotherapy from 2005 to 2012. Materials and Methods A total of 16 patients were identified and 15 eligible patients were included in analysis. Median age was 61 years (range, 40 to 71 years) and 12 patients (80%) were men. Twelve patients (80%) had a tumor in the parotid gland, 9 (60%) had T3 or T4 disease, and 9 (60%) had positive nodal disease. All patients underwent surgery and postoperative radiotherapy. Postoperative radiotherapy was delivered using 3-dimensional conformal radiotherapy or intensity-modulated radiotherapy. Locoregional failure-free survival (LRFFS), distant failure-free survival (DFFS), progression-free survival (PFS), and overall survival (OS) were calculated using the Kaplan-Meier method. Differences in survival based on risk factors were tested using a log-rank test. Results Median total radiotherapy dose was 60 Gy (range, 52.5 to 63.6 Gy). Four patients received concurrent weekly chemotherapy with cisplatin. Among 10 patients who underwent surgery with neck dissection, 7 received modified radical neck dissection. With a median follow-up time of 38 months (range, 24 to 105 months), 4-year rates were 86% for LRFFS, 51% for DFFS, 46% for PFS, and 93% for OS. Local failure was observed in 2 patients (13%), and distant failure was observed in 7 (47%). The lung was the most common involved site of distant metastasis. Conclusion Surgery and postoperative radiotherapy in SDC patients resulted in good local control, but high distant metastasis remained a major challenge. PMID:25324983

Kim, Tae Hyung; Kim, Mi Sun; Choi, Seo Hee; Suh, Yang Gun; Koh, Yoon Woo; Kim, Se Hun; Choi, Eun Chang

2014-01-01

231

Using Massage and Music Therapy to Improve Postoperative Outcomes  

Microsoft Academic Search

•AN EXPERIMENTAL PILOT STUDY was conducted to investigate the effects of preoperative massage and music therapy on patients' preoperative, intraoperative, and postoperative experiences.•PARTICIPANTS were assigned randomly to one of four groups—a group that received massage with music therapy, a group that received massage only, a group that received music therapy only, or a control group.•HEMODYNAMICS, serum cortisol and prolactin levels,

Laura D. McRee; Stacie Noble; Alice Pasvogel

2003-01-01

232

Preoperative Anxiety and Emergence Delirium and Postoperative Maladaptive Behaviors  

Microsoft Academic Search

Based on previous studies, we hypothesized that the clinicalphenomenaofpreoperativeanxiety,emergence delirium, and postoperative maladaptive behavioral changes were closely related. We examined this issue using data obtained by our laboratory over the past 6 years. Only children who underwent surgery and gen- eral anesthesia using sevoflurane\\/O2\\/N2O and who did not receive midazolam were recruited. Children's anxiety was assessed preoperatively with the modified

Zeev N. Kain; Alison A. Caldwell-Andrews; Inna Maranets; Brenda McClain; Dorothy Gaal; Linda C. Mayes; Rui Feng; Heping Zhang

2004-01-01

233

Acute postoperative pain management: focus on iontophoretic transdermal fentanyl  

PubMed Central

Despite progress in the management of chronic pain, acute pain remains an issue for many postoperative patients. Although patient-controlled analgesia (PCA) has demonstrated efficacy and patient satisfaction, current techniques using intravenous (IV) administration present limitations, including the risk of programming errors and the potential to limit patient mobility due to pumps, lines, and tubing. The patient-controlled fentanyl hydrochloride (HCl) iontophoretic transdermal system (fentanyl ITS) was designed to address these concerns. Fentanyl ITS is an innovative, needle-free, self-contained drug-delivery system that uses iontophoretic technology to deliver fentanyl through the skin by application of a low-intensity electrical field. The results of several clinical studies are presented in this review. In three phase 3 placebo-controlled trials, fentanyl ITS was shown to be superior to placebo for the treatment of postoperative pain following major abdominal, orthopedic, and thoracic surgery. The results of one active-comparator phase 3 trial demonstrated comparable safety and efficacy with a standard morphine IV PCA dosing regimen, without significant difference in the side effect profile. Fentanyl ITS represents a safe, easy to use, non-invasive, and convenient alternative to current acute postoperative pain management modalities. PMID:18360612

Mattia, Consalvo; Coluzzi, Flaminia

2007-01-01

234

Early diagnosis of acute postoperative renal transplant rejection  

SciTech Connect

A prospective evaluation of In-111 labeled autologous platelet scintigraphy for the early diagnosis of acute postoperative renal transplant rejection was undertaken. To date, 28 consecutive patients between 7 and 14 days post-op have been injected with 500..mu..Ci of In-111 platelets followed by imaging at 24 and 48 hours. Activity within the renal transplant exceeding activity in the adjacent iliac vessels was considered to be evidence of rejection, and both chemical evidence and clinical impression of rejection at 5 days after completion of imaging was accepted as proof of ongoing or incipient rejection at the time of scintigraphy. In addition, to visual inspection, independent quantitative analysis compared the area-normalized activity over the transplant with the adjacent iliac vessels (normal <1.0). For 5 patients, positive In-111 scintigraphy was present before convincing clinical evidence of rejection. In-111 platelet scintigraphy is useful not only to confirm the clinical diagnosis of rejection but also to establish the early, pre-clinical diagnosis of incipient acute postoperative renal transplant rejection.

Tisdale, P.L.; Collier, B.D.; Kauffman, H.M.; Adams, M.B.; Isitman, A.T.; Hellman, R.S.; Rao, S.A.; Joestgen, T.; Krohn, L.

1985-05-01

235

Efficacy of Postoperative Prophylactic Antibiotic Therapy in Third Molar Surgery  

PubMed Central

Introduction: Surgical extraction of mandibular third molar is the most frequently performed procedure in oral surgery. This procedure is associated with significant postoperative sequelae such as trismus, swelling, pain and infection. The need of antibiotic therapy during the removal of mandibular third molar has been a contentious issue. Method: This study investigated a regimen by using amoxycillin and metronidazole in one group and without using antibiotics in the other. Both the groups were assessed postoperatively on the 1st, 2nd, 5th, 7th and 10th days by the same observer for post operative mouth opening (interincisal distance), presence of a purulent discharge at the site of surgery, pain and swelling. Result: Overall, no statistically significant difference was seen between both the treatment groups when interincisal distance, pain, swelling and purulent discharge were considered. Conclusion: The results of this study failed to show any advantage which was associated with the routine postoperative use of antibiotics in asymptomatic third molar surgeries. PMID:24995236

Reddy B, Praveen

2014-01-01

236

Anterior Lumbar Interbody Fusion for the Treatment of Postoperative Spondylodiscitis  

PubMed Central

Objective To analyze the clinical courses and outcomes after anterior lumbar interbody fusion (ALIF) for the treatment of postoperative spondylodiscitis. Methods A total of 13 consecutive patients with postoperative spondylodiscitis treated with ALIF at our institute from January, 1994 to August, 2013 were included (92.3% male, mean age 54.5 years old). The outcome data including inflammatory markers (leukocyte count, C-reactive protein, erythrocyte sedimentation rate), the Oswestry Disability Index (ODI), the modified Visual Analogue Scale (VAS), and bony fusion rate using spine X-ray were obtained before and 6 months after ALIF. Results All of the cases were effectively treated with combination of systemic antibiotics and ALIF with normalization of the inflammatory markers. The mean VAS for back and leg pain before ALIF was 6.8±1.1, which improved to 3.2±2.2 at 6 months after ALIF. The mean ODI score before ALIF was 70.0±14.8, which improved to 34.2±27.0 at 6 months after ALIF. Successful bony fusion rate was 84.6% (11/13) and the remaining two patients were also asymptomatic. Conclusion Our results suggest that ALIF is an effective treatment option for postoperative spondylodiscitis. PMID:25371780

Kim, Sung Han; Kang, Moo-Sung; Chin, Dong-Kyu; Kim, Keun-Su; Cho, Yong-Eun

2014-01-01

237

Clinical assessment of postoperative sensitivity in posterior composite restorations.  

PubMed

This incidence of postoperative sensitivity was evaluated in resin-based posterior restorations. Two hundred and ninety-two direct restorations were evaluated in premolars and molars. A total of 143 Class I and 149 Class II restorations (MO/OD and MOD) were placed in patients ranging in age from 30 to 50 years. After the cavity preparations were completed, a rubber dam was placed, and the preparations were restored using a total-etch system (Prime & Bond NT) and a resin-based restorative material (TPH Spectrum). The patients were contacted after 24 hours and 7, 30 and 90 days postoperatively and questioned regarding the presence of sensitivity and the stimuli that triggered that sensitivity. The Chi-square and Fisher's Exact Test were used for statistical analysis. Evaluation at 24 hours after restorative treatment revealed statistically significant differences among the types of cavity preparations restored and the occurrence of postoperative sensitivity (p = 0.0003), with a higher frequency of sensitivity in Class II MOD restorations (26%), followed by Class II MO/DO (15%) and Class I restorations (5%). At 7, 30 and 90 days after restorative treatment, there was a decrease in the occurrence of sensitivity for all groups. The percentage of sensitivity among the groups was not significantly different. This study shows that the occurrence of sensitivity is correlated with the complexity of the restoration. PMID:17910217

Briso, André Luiz Fraga; Mestrener, Sandra Rahal; Delício, Giovana; Sundfeld, Renato Herman; Bedran-Russo, Ana Karina; de Alexandre, Rodrigo Sversut; Ambrosano, Glaucia Maria Bovi

2007-01-01

238

Postoperative chylous ascites after radical gastrectomy. A case report.  

PubMed

Postoperative chylous ascites is a classical but uncommon complication following extensive retroperitoneal or near the root of the mesentery dissection with an incidence ranging from 1.2 to 3%. Only 6 cases of chylous ascites have been described after ulcer surgery with troncal vagotomy associated with pyloroplasty and only 1 after gastrectomy. We report the second case of chylous ascites after a D2 distal gastrectomy. A 56-year-old female underwent a D2 distal gastrectomy and gastro-duodenostomy with omentectomy for a prepyloric T1N0M0 moderately differentiated adenocarcinoma. The patient was treated conservatively by both of parenteral nutrition and a fat free diet. By the end of 2(nd) postoperative week, the effusion became serous again and the output gradually ceased. The drain could be removed on the 20(th) postoperative day. Normal enteral nutrition was resumed, no recurrence of chylous ascites occurred. This conservative treatment proved to be effective as it as already be reported with resolution in almost 60% of the patients and remains the first choice option. PMID:12955061

Halkic, N; Abdelmoumene, A; Suardet, L; Mosimann, F

2003-06-01

239

Management of early postoperative coronary artery bypass graft failure  

PubMed Central

Perioperative graft failure following coronary artery bypass grafting (CABG) may result in acute myocardial ischaemia. Whether acute percutaneous coronary intervention, emergency reoperation or conservative intensive care treatment should be used is currently unknown. Between 2003 and 2009, 39 of the 5598 patients who underwent isolated CABG surgery underwent early postoperative coronary angiography for suspected myocardial ischaemia. Following angiography, two groups were identified: patients who underwent immediately reintervention (group 1); and those treated conservatively (group 2). Primary study endpoints were mortality and postoperative myocardial infarct size. Postoperative coronary angiography revealed early perioperative bypass graft failure in 32 of 39 patients. Acute percutaneous coronary intervention was performed in 15 patients, redo-CABG in 4 patients and conservative treatment in 13 patients. The number of failing bypass grafts were significantly higher in group 1 compared with group 2 (P = 0.0251). A trend toward lower post-procedural peak cardiac troponin T and creatinine phosphokinase serum levels in group 1 was observed (163.0 vs. 206.0 and 4.35 vs. 5.53, respectively) (P = 0.0662 and 0.1648). Early reintervention may limit the extent of myocardial cellular damage compared with conservative medical strategy in patients with myocardial ischaemia due to early graft failure. PMID:22223760

Laflamme, Maxime; DeMey, Nathalie; Bouchard, Denis; Carrier, Michel; Demers, Philippe; Pellerin, Michel; Couture, Pierre; Perrault, Louis P.

2012-01-01

240

Postoperative blood loss prevention in total knee arthroplasty.  

PubMed

Blood loss is a serious concern during lower extremity total joint arthroplasty with the estimated reduction in hemoglobin concentration known to vary between 2 and 4 g/dL after total knee arthroplasty (TKA). Allogeneic transfusions are commonly used to treat the acute blood loss and postoperative anemia to diminish the potential cardiovascular risks in up to 50% of such cases with a high volume of blood loss. However, these transfusions are associated with the risks of immunologic reactions, immunosuppression, and infection transmission. Multiple blood-saving strategies have been developed to minimize blood loss, to reduce transfusion rates, to decrease complications, and to improve outcomes in the postoperative period. Currently, there are no clear guidelines on the blood management strategies adopted to lessen the blood loss associated with TKA. The aim of this study was to review the literature and provide a broad summary of the efficacy and complications associated with several blood-saving measures that are currently used in the postoperative period. Evidence suggests that simple techniques such as limb elevation, cryotherapy, compression dressings, and drain clamping may reduce external drainage, however, whether these techniques lead to less allogeneic transfusions is currently debatable. Further research on using a combination of these strategies and their cost-effectiveness are needed. PMID:24122437

Banerjee, Samik; Kapadia, Bhaveen H; Issa, Kimona; McElroy, Mark J; Khanuja, Harpal S; Harwin, Steven F; Mont, Michael A

2013-12-01

241

Hereditary vulnerabilities to post-operative cognitive dysfunction and dementia.  

PubMed

In view of multiple prospective investigations reporting an incidence of 10% or greater in elderly patients after cardiac and non-cardiac procedures, it is surprising that no families, twins or even individual cases have been reported with persistent post-operative cognitive dysfunction (POCD) or post-operative dementia (POD) that is otherwise unexplained. As POCD and POD research has shifted in recent years from surgical and anesthetic variables to predictors of intrinsic, patient-specific susceptibility, a number of markers based on DNA sequence variation have been investigated. Nevertheless, no heritable, genomic indices of persistent POCD or post-operative dementia lasting 3 months or longer after surgery have been identified to date. The present manuscript surveys challenges confronting the search for markers of heritable vulnerability to POCD and POD, and proposes steps forward to be taken now, including the addition of surgical and anesthetic descriptors to ongoing longitudinal dementia protocols and randomized clinical trials (RCTs) comprising serial psychometric testing, and a fresh focus on phenotypes and genotypes shared between outliers with "extreme" POCD and POD traits. PMID:23562862

Hogan, Kirk J

2013-12-01

242

Sozialisationstheorien: Traditionslinien, Debatten und Perspektiven  

Microsoft Academic Search

\\u000a Der Begriff der Sozialisation bezieht sich auf die Entwicklung des Individuums in seinem Verhältnis zur Umwelt. Dieses Verhältnis\\u000a wird theoretisch-konzeptuell hinsichtlich der Subjektkonzepte, der sozialisatorischen Umwelten und der Gewichtung ihrer jeweiligen\\u000a Bedeutung (nature vs. nurture) sowie ihrer Verwobenheit ineinander unterschiedlich gefasst. Hieraus haben sich, philosophisch\\u000a fundiert, verschiedene theoretische Traditionslinien entwickelt, an denen wissenschaftliche Disziplinen wie die Soziologie,\\u000a Psychologie, Erziehungswissenschaft, Ethnologie,

Renate Nestvogel

243

Geerbte Aggression: Gene und Gewalt  

Microsoft Academic Search

Die Frage nach den Wurzeln von Aggression und Gewalt wird seit langer Zeit als Kontroverse um »Anlage« vs »Umwelt« heft ig\\u000a diskutiert. Wenn sowohl Vater wie auch Sohn wegen Gewalttaten im Gefängnis sitzen, wird in der Öffentlichkeit manchmal über\\u000a ein »Aggressionsgen« spekuliert. Wenn Jugendliche in heruntergekommenen Stadtteilen oder junge Männer aus Migrantenfamilien\\u000a zuschlagen, wird ihre gesellschaft liche Umwelt als Ursache

Klaus Wahl

244

Sozialisationstheorien: Traditionslinien, Debatten und Perspektiven  

Microsoft Academic Search

Der Begriff der Sozialisation bezieht sich auf die Entwicklung des Individuums in seinem Verhältnis zur Umwelt. Dieses Verhältnis\\u000a wird theoretisch-konzeptuell hinsichtlich der Subjektkonzepte, der sozialisatorischen Umwelten und der Gewichtung ihrer jeweiligen\\u000a Bedeutung (nature vs. nurture) sowie ihrer Verwobenheit ineinander unterschiedlich gefasst. Hieraus haben sich, philosophisch\\u000a fundiert, verschiedene theoretische Traditionslinien entwickelt, an denen wissenschaftliche Disziplinen wie die Soziologie,\\u000a Psychologie, Erziehungswissenschaft, Ethnologie,

Renate Nestvogel

245

Forschen und Wissen info38 6/2011 Forschen und Wissen 39 Das Bundesministerium fr Bildung und  

E-print Network

, 206.150 Euro für die Dauer von drei Jahren. Gefördert wird das Forschungs- vorhaben ,,Die Rolle von dendritischen Zellen bei der Integration von Toll-like-Re- zeptor-ermittelten Signalwegen in pro- und anti in besonderer Weise erkenn- bar und unterliegen damit gleichsam einer ,,verschärften �berwachung" durch die

Manstein, Dietmar J.

246

An alternative postoperative pathway reduces length of hospitalisation following oesophagectomy???  

PubMed Central

Objective As part of our ongoing quality improvement effort, we evaluated our conventional approach to post-oesophagectomy management by comparing it to an alternative postoperative management pathway. Methods Medical records from 386 consecutive patients undergoing oesophagectomy with gastric conduit for oesophageal cancer or Barrett’s oesophagus with high-grade dysplasia were analysed retrospectively (July 2004 to August 2008). The conventional pathway involved a routine radiographic contrast swallow study at 5—7 days after oesophagectomy with initiation of oral intake if no leak was detected. In the alternative pathway, a feeding jejunostomy was placed for enteral feeding and used exclusively until oral intake was gradually initiated at home at 4 weeks after oesophagectomy. No contrast swallow was obtained in the alternative pathway group unless indicated by clinical suspicion of an anastomotic leak. Each group was analysed on an intention-to-treat basis with respect to anastomotic leak rates, length of hospitalisation, re-admission and other complications. Results A total of 276 (72%) patients underwent conventional postoperative management, 110 (28%) followed the alternative pathway. Patient characteristics were similar in both the groups. The anastomotic leak rate was lower in the alternative pathway with three clinically significant leaks (2.7%) versus 33 in the conventional pathway (12.0%; p = 0.01). Among patients undergoing a radiographic contrast swallow examination, a false-negative rate of 5.8% was observed. The swallow study of 14 patients (5.9%) was complicated by aspiration of oral contrast. Postoperatively, 7.3% of patients suffered from pneumonia. There were no significant differences overall in postoperative pulmonary or cardiac complications associated with either pathway. Median length of hospitalisation was 2 days shorter for the alternative pathway (7 days) than the conventional pathway (9 days; p < 0.001). There was no significant difference in unplanned re-admission rates. Conclusion An alternative postoperative pathway following oesophagectomy involving delayed oral intake and avoidance of a routine contrast swallow study is associated with a shortened length of hospitalisation without a higher risk of complication after hospital discharge. PMID:19900819

Tomaszek, Sandra C.; Cassivi, Stephen D.; Allen, Mark S.; Shen, K. Robert; Nichols, Francis C.; Deschamps, Claude; Wigle, Dennis A.

2010-01-01

247

Klinik, Symptomatik und Therapiestrategien bei Keimzelltumoren des Ovars  

Microsoft Academic Search

Zusammenfassung Ovarialle Keimzelltumoren bei Kindern und Jugendlichen verhalten sich sehr heterogen. Sie entwickeln sich aus totipotenten primordialen Keimzellen und können einen klinisch gutartigen (z. B. Teratome) oder äußerst aggressiven metastasierenden Verlauf nehmen (z. B. Choriokarzinom). Histologische Differenzierung, Krankheitsverlauf und zu erwartendes Ansprechen auf die Chemotherapie korrelieren eng mit der Produktion der Tumormarker AFP und ?-HCG, die daher bei jedem Ovarialtumor dieser Altersgruppe

U. Göbel; G. Calaminus; D. T. Schneider; T. Löning

2004-01-01

248

Ringvorlesung Psychotherapie Klinische Psychologie und Psychotherapie, Universitt Bielefeld  

E-print Network

Psychotherapie Klinische Psychologie und Psychotherapie, Universität Bielefeld Einer krank ­ Beide betroffen Familienangehörigen. Die Modell- und Theorienbildung in der Klinischen Psychologie und Psychotherapie orientiert sich Psychotherapie kann jedoch von erheblicher Bedeutung sein und zwar nicht nur für die Patienten selbst, sondern

Moeller, Ralf

249

Kultur-, Sozial-und Bildungswissenschaftliche Fakultt Fachspezifische  

E-print Network

Implikatio- nen), die für die Ausübung von konzept- und wis- Die Universitätsleitung hat die Studienordnung soziale Praxis (10 LP) Modul III: Gattungen und Kanonisierungsprozesse (10 LP) Modul IV: Musiktheorie/Musikanalyse (10 LP) Modul V: Musik, Technologien, Kulturtechniken (10 LP) Modul VI: Interpretation, Performance

Röder, Beate

250

Die Absorptionsspektren von Vanadium, Titan und Scandium  

Microsoft Academic Search

Zusammenfassung Unter Benutzung eines elektrischen Ofens nach dem Muster der Öfen von A. King werden die Absorptionslinien der Dämpfe von Vanadium, Titan und Scandium bei 20000 C ermittelt. Die quantentheoretische Deutung dieser Ergebnisse gelingt unter Benutzung der bisher bekannten Gesetzmäßigkeiten in den Bogenspektren dieser Elemente, die einer kritischen Durchsicht unterzogen und insbesondere bei Titan durch Angabe neuer Multipletts vervollständigt werden.

H. Gieseler; W. Grotrian

1924-01-01

251

Universitt Paderborn Fakultt Elektrotechnik, Informatik und Mathematik  

E-print Network

2003 #12; iv Tabellenbasierte arithmetische Kodierung bei allgemeinen Alphabeten #12; v Für meine A T E X 2 " unter RedHat Linux 7.3. Mein Dank gilt Donald Knuth, Leslie Lamport und Linus Torvalds für sowie Elisabeth Kappius, Gabriele Kappius und Mirko Hessel für die Hilfe im Kampf gegen die deutsche

252

Die letzten Aufklrer Sherlock Holmes und Kollegen  

E-print Network

Die letzten Aufklärer Sherlock Holmes und Kollegen Detektive, Fahnder und Agenten aus zwei Sherlock Holmes wurde ein Protagonist geboren, der für viele literarische Fahnder nach ihm, zumindest zum aber zunächst Sherlock Holmes mit all seinen Bearbeitungen (Filme, Comics usw.) gewidmet. Ein Projekt

Ullmann, G. Matthias

253

BER DIE WIRKUNG VON POLLENEXTRAKTEN UND DUFTSTOFFEN  

E-print Network

Ã?BER DIE WIRKUNG VON POLLENEXTRAKTEN UND DUFTSTOFFEN AUF DAS SAMMEL- UND WERBEVERHALTEN HÃ?SELNDER MATTERS ON THE COLLECTING AND RECRUITING ACTIVITIES OF HONEY-BEES ( 4PIS MELLIFICA L.) 1. With extracts of alder-pollen, hazel pollen, and a mixture of pollen it was possible to release vivid dancing among bees

Boyer, Edmond

254

Die kombinierte Kompressionsmarknagelarthrodese von OSG und USG  

Microsoft Academic Search

Zusammenfassung Die operative Versteifung von oberem (OSG) und unterem Sprunggelenk (USG) ist bei fortgeschrittenen degenerativen Veränderungen beider Gelenke unterschiedlicher Genese auch bei zunehmender Verbreitung des Oberflächenersatzes am OSG die Therapie der Wahl. Bisher sind verschiedene Techniken zur tibiotalokalkanealen Arthrodese beschrieben worden, wobei sich die Kompressionsarthrodese mit internen Implantaten durchgesetzt hat. 20 Patienten, bei denen die kombinierte Arthrodese von OSG und

M. Goebel; T. Mückley; L. Gerdesmeyer; M. Militz; V. Bühren

2003-01-01

255

Qigong-Kurs Qigong -Bewegung und Stille  

E-print Network

Qigong-Kurs Datum 16.12.2011 Seite -2- Qigong - Bewegung und Stille Kursleiter: Peter Schwarz Theorie des QiGong. Praxisübungen bilden den Schwerpunkt. Qigong ­ vier Bahnen in die Stille Der Ausdruck Qigong, die �bungspraxis und die dahinterstehende Theorie stammen aus der chinesischen Tradition. Mit

Szmolyan, Peter

256

Institut fr Public Health und Pflegeforschung  

E-print Network

Institut für Public Health und Pflegeforschung Geschäftsstelle Fachbereich 11 Human- und) 218 ­ 68980/-68880 eMail health@uni-bremen.de www www.ipp.uni-bremen.de Das Institut für Public Health Informationstechnologie, bei entsprechender Vorerfahrung auch aus den Bereichen Public Health, Pflege oder Psychologie

257

Erwerbspersonen- und Arbeitsvolumenprojektionen bis ins Jahr 2060  

Microsoft Academic Search

Diese Arbeit analysiert die Auswirkungen des demografischen Wandels auf das Arbeitsangebot und leitet auf Basis verschiedener Szenarien Politikempfehlungen ab, um dem demografisch bedingten Arbeitskräfterückgang zu begegnen. In einem ersten Schritt werden hierbei Erwerbspersonenprojektion anhand eines Kohorten-Komponenten-Modells vorgenommen und durch verschiedene Modellrechnungen ergänzt. Neben einer Abschätzung der Erwerbspersonenzahl bei einer Erhöhung des effektiven Renteneintrittsalters werden die Konsequenzen eines früheren Erwerbseintritts, einer

Daniel Ehing; Stefan Moog

2012-01-01

258

Fnfte Satzung zur nderung der Fachstudien-und Prfungsordnung fr den Masterstudiengang Marketing der Rechts-und Wirtschafts-  

E-print Network

Marketing der Rechts- und Wirtschafts- wissenschaftlichen Fakultät der Universität Erlangen �nderungssatzung: § 1 Die Fachstudien- und Prüfungsordnung für den Masterstudiengang Marketing der Rechts- und-Business Intelligence and Relationships 5 5 ,, 9. Die Zeilen 83 (neu) (B2/Weitere Pflichtfächer) und 84 (neu) (B2/E

Fiebig, Peter

259

Die Entwicklung des Spießens und Klemmens bei den drei Würgerarten Lanius collurio, L. senator und L. excubitor  

Microsoft Academic Search

Zusammenfassung Die Verhaltensweisen des Aufspießens und Festklemmens von Beute bei der GattungLanius wurde vonLorenz (1935) als eine „Verschränkung“ einer angeborenen Bewegungskoordination mit einer erlernten Orientierung nach einer Spieß- oder Klemmgelegenheit aufgefaßt. An drei Würgerarten,L. collurio, L. senator undL. exubitor wurde das Zusammenspiel phylogenetisch angepaßter und individuell erlernter Information beim Aufspießen und Festklemmen erneut untersucht.

Konrad Lorenz; Ursula von Saint Paul

1968-01-01

260

A Comparative Clinical Evaluation of the Effect of Preoperative and Postoperative Antimicrobial Therapy on Postoperative Sequelae after Impacted Mandibular Third Molar Extraction  

PubMed Central

ABSTRACT Objectives To compare the effect of preoperative and postoperative antibiotics therapy on postoperative sequelae after impacted mandibular third molar extractions. Material and Methods This was a prospective study conducted at Department of Oral and Maxillofacial Surgery of the Lagos University Teaching Hospitalon consecutive patients with impacted third molar extractions for a 12 month period. Group I (n = 31) had administration of 1 gram of oral metronidazole and 1 gram of amoxicillin capsules 30 minutes preoperative and Group II (n = 31) had 500 milligrams of amoxicillin capsule 8 hourly and 400 milligrams of metronidazole tablets administered post operatively for 5 days. Pain, facial swelling and mouth opening assessment were done postoperatively and on days 1, 3 and 7. Results The general pattern of postoperative pain, regardless of antimicrobial use revealed that pain increased from day 1 to day 3 postoperatively and began to decrease in intensity subsequently up to the seventh day. There was however a statistically significant difference (P = 0.0001) between the two groups on the 7th postoperative day with the subjects in Group I showing lower pain intensity. The mean difference of the facial width on days 1 and 3 was significant (P = 0.04 and P = 0.0001 respectively) with subjects in Group II having a reduced facial width compared to those in Group I. Conclusions This study suggested that the administration of preoperative or postoperative antibiotics showed no marked differences in the degree of postoperative sequaele that occur after impacted mandibular third molar extractions. PMID:25089174

Gbotolorun, Olalekan Micah; Ibikunle, Adebayo Aremu; Emeka, Christian Ibezi; Arotiba, Godwin Toyin; Akinwande, Jelili Adisa

2014-01-01

261

[Treatment of postoperative alcohol withdrawal syndrome after esophageal resection].  

PubMed

Prophylaxis and treatment of alcohol withdrawal syndrome following esophagectomy consists of substitution with alcohol (1-2 g/kg/d), monotherapy with Midazolam (0.2-0.4 mg/kg/h) und Clonidin (1-2 mg/d). Out of 218 patients undergoing esophagectomy from X/86 till III/90 52 were classified as alcoholics and divided in 3 comparable groups. The Midazolamgroup showed the best results as far as withdrawal symptoms, time at the ICU, ventilation time, respiratory complications, delirium tremens and mortality are concerned. Patients in the Clonidin-group needed extensive supplimentary sedation. PMID:1983500

Huber, F T; Bartels, H; Siewert, J R

1990-01-01

262

Zur Ökologie und Biologie der Ernährung einiger Limikolen-Arten  

Microsoft Academic Search

Zusammenfassung 1.Auf Grund von Wattkartierungen, Freilandbeobachtungen und Untersuchungen von Magen- und Darminhalten der LimikolenartenCalidris alpina, Calidris canutus undCrocethia alba sowie von Gefangenschaftsbeobachtungen wurde die Ernährung dieser Vogelarten auf dem Watt der Vogelinsel Mellum untersucht.2.Bei den Wattuntersuchungen wurde an die Arbeiten vonLinke (1939) undO. Schuster (1951) angeknüpft. Durch Sedimentproben wurde ermittelt, daß das Mellum-Watt überwiegend aus Feinsand besteht und damit als

Wilfrid Ehlert

1964-01-01

263

Postoperative pain treatment after total hip arthroplasty: a systematic review.  

PubMed

Treatment of postoperative pain should rely on results from randomized controlled trials and meta-analyses of high scientific quality. The efficacy of a particular intervention may depend on the type of surgical procedure, which supports the reporting of "procedure-specific" interventions. The aim of this systematic review was to document the procedure-specific evidence for analgesic interventions after total hip arthroplasty (THA). This PRISMA-compliant and PROSPERO-registered review includes randomized placebo-controlled trials (RCTs) of medication-based analgesic interventions after THA. Endpoints were postoperative opioid consumption, pain scores (rest and during mobilization), adverse events, and length of hospital stay. Fifty-eight trials with 19 different interventions were retrieved. High risk of bias, substantial differences in assessment-tools and criteria for pain, irregular reporting of adverse events, considerable differences in supplemental analgesic consumption, and basic analgesic regimens generally characterized trials. Meta-analyses of non-steroidal anti-inflammatory drugs, local infiltration analgesia, intrathecal opioids, and lumbar plexus block provided a 24-hour intravenous morphine-sparing effect of 14.1 (95 % confidence interval: 8.0-20.2) mg, 7.5 (3.7-11.3) mg, 19.8 (14.9-24.7) mg, and 11.9 (6.4-17.3) mg, respectively. Non-steroidal anti-inflammatory drugs and lumbar plexus block were demonstrated to provide reductions in postoperative pain scores. Intrathecal opioids increased pruritus, and lumbar plexus block reduced nausea and pruritus. The GRADE-rated quality of evidence ranged from low to very low throughout the analyses. This review demonstrated, that some analgesic interventions may have the capacity to reduce mean opioid requirements and/or mean pain intensity compared with controls, but the available randomized placebo-controlled trials does not allow a designation of a "best proven intervention" for THA. PMID:25599296

Højer Karlsen, Anders Peder; Geisler, Anja; Petersen, Pernille Lykke; Mathiesen, Ole; Dahl, Jørgen B

2015-01-01

264

The preoperative evaluation prevent the postoperative complications of thyroidectomy  

PubMed Central

Objective Thyroid surgery is generally a safe surgery but its complications are still common. We wish to identify preoperative factors that predict postoperative complications. Methods A nationwide survey was conducted by senior surgeons from 16 medical centers and 5 regional hospitals in Taiwan to thyroid operations performed over 3 years. 3846 cases were retrospectively examined to identify factors influencing complications: indication for surgery, preoperative evaluation, such as ultrasonography, chest X-ray, computed tomography and magnetic resonance imaging, isotope scanning, fine-needle aspiration cytology (FNAC) and thyroid function test, and patient characteristics. Results Eighty-four percent of patients were female. Seven percent of the patients had immediate postoperative hypocalcemia (mild and severe) and 2.3%, hoarseness (recurrent laryngeal nerve (RLN) injury, temporary/permanent). Logistic regression analysis identified an association between hypocalcemia and RLN injury with age, hospital category, surgical procedure types (total thyroidectomy, unilateral, bilateral subtotal or total resection). A lower incidence of hypocalcemia was related to preoperative neck ultrasound and FNAC analysis (the odds ratio (OR) = 0.5 and 0.65, [95% confidence interval (CI) 0.331–0.768 and 0.459–0.911], P = 0.0014 and 0.0127, respectively), while RLN injury was not associated with any preoperative evaluation. The ORs of hypocalcemia and RLN injury for patients older than 50 years were 0.55 and 2.15, [0.393–0.763 and 1.356–3.4], P < 0.001 and 0.0012, respectively. Conclusions The success of thyroid surgery depends on careful preoperative planning, including a preoperative neck ultrasound to determine the proximity of the nodule to the recurrent laryngeal nerve course, and the consideration of the type of anesthesia, adjuvant devices for intra-op monitoring of the RLN, and surgical modalities. Our results suggest that preoperative evaluation implementations are positively associated with strategy of surgery and postoperative hypocalcemia prevention.

Huang, Chien-Feng; Jeng, Yachung; Chen, Kuo-Dong; Yu, Ji-Kuen; Shih, Chao-Ming; Huang, Shih-Ming; Lee, Chen-Hsen; Chou, Fong-Fu; Shih, Ming-Lang; Jeng, Kee-Ching; Chang, Tzu-Ming

2014-01-01

265

Postoperative analgesic effect of epidural neostigmine following caesarean section  

PubMed Central

Aim: The aim of this study was to evaluate the analgesic effects of postoperative epidural administration of neostigmine and morphine in patients scheduled for caesarean section under epidural anaesthesia. Material and Methods: Sixty ASA I-II patients, scheduled for caesarean section under epidural anaesthesia, were randomly allocated into three groups. Neostigmine (10 ?g/kg), morphine (3 mg), and saline (6 mL) were administered to the neostigmine, morphine, and control groups, respectively, 30 minutes after the surgery via the epidural catheter. Afterwards, postoperative pain treatment was administered to all patients with a patient-controlled epidural analgesia (PCEA) device, using 0.125% bupivacaine. The patients were followed up for 24 hours. The total volume of local anaesthetics used, the time to first analgesic requirement, analgesic requirements, VAS scores, analgesia quality, first passage of bowel gas, ambulation times, haemodynamic parameters and side effects were evaluated. Results: The time to first analgesic requirement was significantly longer in the morphine group than in the neostigmine and control groups (p<0.01), and in the neostigmine group compared to the control group (p<0.05). The total local anaesthetic consumption and the number of bolus injections were significantly higher in the control group than in the other groups (p<0.01). The first passage of bowel gas occurred significantly sooner in the neostigmine group than in the morphine (p<0.01) and the control (p<0.05) groups. Itching frequency was significantly higher in the morphine group than in the other two groups (p<0.05). VAS scores were similar in the morphine and neostigmine groups. Conclusion: Postoperative single-dose epidural neostigmine reduced the 24-hour analgesic requirements but in the chosen doses presented an analgesic effect significantly lower than morphine. Hippokratia 2014; 18 (1): 44-48. PMID:25125952

Alkan, M; Kaya, K

2014-01-01

266

[Introduction on postoperative nutritional support in neonatal cardiac surgery].  

PubMed

Malnutrition is common in newborn patients after cardiac surgery, because of the low metabolic reserves, increased energy expenditure caused by the injury, and reduced or delayed nutritional support they receive, as well as their inability to metabolize the nutrients administered. It is important to achieve appropriate nutrition; a better metabolic response after surgery has a significant impact on length of stay, wound healing, susceptibility to infections and surgical outcome. This guideline intended to establish the practical foundation for parenteral and enteral nutritional support in the newborn with cardiac surgery, considering water restriction, optimizing macro and micronutrients required in the postoperative time. PMID:25192526

Oeschger, Vanesa Verónica; Mazza, Carmen Silvia; Araujo, María Beatriz; Sauré, Carola

2014-10-01

267

Management strategies to reduce risk of postoperative infections  

PubMed Central

Postoperative infections, although rare, are still of great concern to the ophthalmologist. The incidence of post-cataract endophthalmitis is low, with a range of .28 per 1,000 to 2.99 per 1000. In addition to intraoperative considerations such as poor wound construction, vitreous loss, topical anesthesia, and prolonged surgical time, other risk factors include preoperative factors such as a diseased ocular surface and systemic immunosuppression. Potential methods of reducing risk of endophthalmitis after anterior segment surgery are discussed and available literature is summarized. PMID:24319649

Galor, Anat; Goldhardt, Raquel; Wellik, Sarah R.; Gregori, Ninel Z.; Flynn, Harry W.

2013-01-01

268

A Radiobiological Analysis of Multicenter Data for Postoperative Keloid Radiotherapy  

SciTech Connect

Purpose: To identify factors significantly affecting recurrence rates after postoperative external beam radiotherapy (XRT) of keloids, and to delineate any radiation dose response and effects of radiation dose per fraction. Methods and Materials: A comprehensive literature review was performed to compile a database of 2,515 resected keloids (36.9% earlobe). Postoperative XRT was 45- to 100-kV X-rays in 27.0% or 120- to 250-kV X-rays in 11.1%, Co-60 in 1.9%, Sr-90 in 4.7%, 1.5- to 9-MeV electrons in 26.5%, and no XRT in 28.8%. In the 1,791 irradiated patients, the median radiation parameters were as follows: total dose, 15 Gy (range, 6-30 Gy); dose per fraction, 5.0 Gy (range, 2-15 Gy); fractions, 3 (range, 1-10); and time, 7 days (range, 0-33 days). Results: Multivariate stepwise logistic regression correlated decreased keloid recurrence with earlobe location (p = 1.98E-10; odds ratio, 0.34), biologically effective dose (p = 1.01E-27), and treatment with electron beam or Co-60 vs. other techniques (p = 0.0014; odds ratio, 0.72). Different radiobiological models calculated values of {alpha}/{beta} = 1.12 to 2.86 (mean, 2.08) and time (repopulation) correction factors for biologically effective dose from 0.98 to 2.13 Gy per day (mean, 1.34) starting 10 days after surgery. Different models (with {alpha}/{beta} = 2.08) predicted that doses needed for 90% and 95% control with 3 fractions of postoperative electron beam were 16.0 to 16.2 Gy and 18.3 to 19.2 Gy, respectively, in less than 10 days for earlobe keloids and 21.5 to 22.2 Gy and 23.4 to 24.8 Gy, respectively, in less than 10 days for other sites. Conclusions: Postoperative keloid radiotherapy requires moderately high doses and optimal technique to be effective. The relatively low {alpha}/{beta} ratio indicates that radiotherapy with a limited number of fractions and high doses per fraction is the best strategy.

Flickinger, John C., E-mail: flickingerjc@upmc.ed [Departments of Radiation Oncology and Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA (United States)

2011-03-15

269

[Postoperative opacification of posterior chamber intraocular lenses - a review].  

PubMed

Postoperative opacification of intraocular lenses (IOLs) is a very unpleasant complication for the ophthalmic surgeon and the patient. We report on our experiences with opacification of different foldable IOL designs and rigid poly (methyl methacrylate) (PMMA) posterior chamber lenses.1. Snowflake degeneration of PMMA IOLs: This condition is an unanticipated and surprising late postoperative finding 8 to 15 years after implantation. In our opinion, this complication is probably not related to the PMMA biomaterial itself, but rather it appears to represent a manufacturing problem that has affected a selected, albeit large number of lenses manufactured in the 1980s-mid 1990s.2. Degeneration of UV absorber material and calcium deposits within the optic of hydrophilic IOLs: Two years postoperatively degenerations of UV absorber material and calcium deposits within the optic of single piece hydrophilic acrylic lenses SC60B-OUV manufactured by MDR (Medical developmental research Inc. Clearwater FL, USA) can occur. Although the precise mechanism is not fully known, it was assumed that these opacifications are due to premature aging of the UV blocking agent incorporated in the lens biomaterial and calcification.3. Calcification on the surface of the Bausch & Lomb Hydroviewtrade mark IOLs: Twelve to 15 months postoperatively granular surface calcifications in Hydroviewtrade mark IOLs occured. The mechanism is not fully understood. According to Bausch and Lomb studies, part of the components of the packaging contained silicone, which may have come off the packaging onto the lens optic, where it then appears to be a catalyst for calcium precipitation. The manufacturer has correlated a change in packaging with the appearance of the opacification. The manufacturer now believes that this problem has been solved. However, final verification will require a careful 1 - 2 years clinical study.4. Glistenings in the hydrophobic acrylic AcrySoftrade mark IOLs: The time frame of glistenings in the AcrySoftrade mark IOLs is highly variable. It has been suggested that the occurrence of glistenings may be related to variations in the temperature of the lens just prior to and or during insertion into the eye. Formation of vacuoles may occur within the submersed acrylic polymer when there is a transient increase and then decrease in temperature during the surgical procedure. "Glistenings" may then subsequently form by ingress of anterior chamber fluid. Contrast sensitivity can been decreased in some patients, but clinically significant decrease of visual acuity has been rare. PMID:11590465

Schmidbauer, J M; Werner, L; Apple, D J; Pandey, S K; Izak, A M; Trivedi, R H; Macky, T A; Auffarth, G U; Peng, Q; Arthur, S N; Escobar-Gomez, M; Ma, L; Vargas, L G

2001-09-01

270

Postoperative evaluation of penetrating hepatic trauma and complications  

SciTech Connect

Postoperative hepatobiliary scintigraphy is recommended in selected cases of hepatic trauma to evaluate the integrity and patency of the biliary system. The authors present a patient with a traumatic hematoma that eventuated in a biloma with spontaneous biliary-cutaneous fistula. Repeat study demonstrated biliary obstruction at the canalicular level, which by more invasive imaging was found secondary to toal obstruction of the common hepatic duct. The precise anatomical level and cause of his obstruction were defined by the findings of endoscopic retrograde cannulation of the pancreas, percutaneous transhepatic cholangiongraphy, and surgery.

Lecklitner, M.L.; Dittman, W.

1984-09-01

271

Low immediate postoperative platelet count is associated with hepatic insufficiency after hepatectomy  

PubMed Central

AIM: To investigate the relationship between low immediate postoperative platelet count and perioperative outcome after liver resection in patients with hepatocellular carcinoma (HCC). METHODS: In a cohort of 565 consecutive hepatitis B-related HCC patients who underwent major liver resection, the characteristics and clinical outcomes after liver resection were compared between patients with immediate postoperative platelet count < 100 × 109/L and patients with platelet count ? 100 × 109/L. Risk factors for postoperative hepatic insufficiency were evaluated by multivariate analysis. RESULTS: Patients with a low immediate postoperative platelet count (< 100 × 109/L) had more grade III-V complications (20.5% vs 12.4%, P = 0.016), and higher rates of postoperative liver failure (6.8% vs 2.6%, P = 0.02), hepatic insufficiency (31.5% vs 21.2%, P < 0.001) and mortality (6.8% vs 0.5%, P < 0.001), compared to patients with a platelet count ? 100 × 109/L. The alanine aminotransferase levels on postoperative days 3 and 5, and bilirubin on postoperative days 1, 3 and 5 were higher in patients with immediate postoperative low platelet count. Multivariate analysis revealed that immediate postoperative low platelet count, rather than preoperative low platelet count, was a significant independent risk factor for hepatic insufficiency. CONCLUSION: A low immediate postoperative platelet count is an independent risk factor for hepatic insufficiency. Platelets can mediate liver regeneration in the cirrhotic liver. PMID:25206294

Wang, Hai-Qing; Yang, Jian; Yang, Jia-Yin; Wang, Wen-Tao; Yan, Lu-Nan

2014-01-01

272

Untersuchungen über die Extraktion und Extraktionschromatographie von Uran(IV) mit Phosphorsäureestern und alkylsubstituierten Ammoniumnitraten aus wäßriger Salpetersäure  

Microsoft Academic Search

Zusammenfassung Das extraktive und extraktionschromatographische Verhalten von Uran(IV) zwischen wäßriger Salpetersäure und organischen Extraktionsmitteln wird beschrieben. Als Extraktionsmittel wurden Tri-n-butylphosphat, Di-(2-äthylhexyl) -phosphorsäure und die Nitratsalze der Amine Primene JM-T (ein primäres Amin), Amberlite LA-1 (ein sekundäres Amin), Trilaurylamin (ein tertiäres Amin) und das quartäre Ammoniumsalz Hyamine-1622 in der Nitratform eingesetzt. Die extraktiv mit Scheidetrichtern und extraktionschromatographisch mit Glaskolonnen bestimmten Uran(IV)-Verteilungsverhältnisse

Erich R. Schmid

1972-01-01

273

Strahlteilungs- und Interferenzexperimente mit Photonenpaaren  

NASA Astrophysics Data System (ADS)

Wir führen eine Reihe von elementaren optischen Experimenten mit einem nichtklassischen Lichtfeld durch, das über parametrische Fluoreszenz erzeugt wird und die Besonderheit aufweist, daß die Photonen ausschließlich paarweise auftreten. Beim Auftreffen auf einen verlustfreien, teildurchlässigen Spiegel werden die Photonen eines Paares gemäß einer Binomialverteilung auf das reflektierte und das transmittierte Bündel verteilt. Dieses Ergebnis ist unabhängig vom Kohärenzgrad. Die beobachtete Invarianz der Verteilung kann auf eine Balance zwischen quantenmechanischen Stimulations- und Interferenzeffekten in den Ein- und Ausgangsarmen des Strahlteilers zurückgeführt werden. Beim zweimaligen Durchlaufen eines Strahlteilers in einem Michelson-Interferometer treten Interferenzen zwischen den verschiedenen möglichen Zweiphotonenzuständen im Interferometer auf. Das Korrelations-Interferogramm für Photonenpaare besitzt eine höhere Auflösung als das Intensitäts-Interferogramm für die Transmission einzelner Photonen. Wir deuten dieses Verhalten als quantenmechanische Interferenz zwischen der größeren Zahl von Möglichkeiten, die ein Photonenpaar im Vergleich zu einzelnen Photonen hat, das Interferometer zu durchlaufen. Die Anwendung dieser Überlegungen auf Lichtfelder mit Paaren von Photonen unterschiedlicher Energie führt zu Korrelations-Interferogrammen, die deutlich von den mit klassischen Feldern aufgenommenen Interferogrammen abweichen.Translated AbstractBeam Splitting and Interference Experiments with Photon PairsWe perform a series of elementary optical experiments with a nonclassical lightfield generated in the process of spontaneous parametric down-conversion. This lightfield consists of photon pairs only. When the photon pairs fall on a lossless beam splitter the photons are distributed among the transmitted and reflected beam according to the binomial distribution. The result is independent of the degree of coherence. The invariance of the distribution can be understood as a balance between quantum mechanical stimulation and interference effects in the input and output arms of the beam splitter. In application to a Michelson interferometer in which the beam splitter is passed twice we have to consider interferences between the possible two-photon states. Compared to conventional Michelson interferograms the measured correlation interferogram for photon pairs exhibits a higher resolution. We explain this behavior as due to quantum mechanical interference between the larger number of ways a photon pair can traverse the interferometer compared to single photons. Applied to lightfields in which the photons of a pair have different energies these considerations lead to correlation interferograms which differ significantly from those recorded with classical lightfields.

Brendel, J.; Lange, R.; Mohler, E.; Martienssen, W.

274

Kosten und Komplikationen der Materialentfernung  

Microsoft Academic Search

Zusammenfassung  Die Implantatentfernung ist eine der häufigsten orthopädisch-traumatologischen Operationen. Da dabei z. T. schwer wiegende\\u000a Komplikationen auftreten, sind besonders die relativen Indikationen, v. a. bei Beschwerdefreiheit des Patienten, kritisch\\u000a zu werten. Neben den allgemeinen Komplikationen der Implantatentfernung wie Infektionen sind v. a. typische Komplikationen\\u000a wie Refrakturen, Nervenläsionen, nach Implantatentfernung neu aufgetretene Schmerzen und unvollständige Implantatentfernung\\u000a zu nennen. Speziell die winkelstabilen Implantate lassen eine neue

M. Müller; T. Mückley; G. O. Hofmann

2007-01-01

275

Tycho Brahe - Instrumentenbauer und Meister der Beobachtungstechnik  

NASA Astrophysics Data System (ADS)

Vor der Erfindung des Fernrohrs war der dänische Astronom Tycho Brahe (1546 - 1601) der bedeutendste beobachtende Astronom. Von seinem Observatorium Uraniborg auf der - damals dänischen - Insel Hven ist heute noch der Grundriß erkennbar, von Stjerneborg sind die Fundamente erhalten, die Kuppeln in den 1950er Jahren ergänzt. In der Astronomie-Ausstellung im Deutschen Museum gibt es ein Modell der Sternwarte Uraniborg und der zugehörigen Instrumente (Maßstab 1:10); das größere Modell wurde dem Technischen Museum in Malmö geschenkt. Die Instrumente, die er in den Observatorien Uraniborg und Stjerneborg benutzte, sind nicht erhalten. Aber es gibt gute Beschreibungen der Instrumente (Halbkreis, Quadranten, Sextanten, Armillarsphären, Triquetrum, Himmelsglobus) in seinem Buch Astronomiae instauratae mechanica (Wandsbek 1598). Eine Nachbildung des großen hölzernen Quadranten kann man im Runden Turm in Kopenhagen sehen. Zwei Sextanten, hergestellt für Tycho um 1600 von Jost Bürgi und Erasmus Habermel, gibt es noch im Nationalmuseum für Technik in Prag. Ähnlichkeiten von Tychos Instrumenten mit Groß-Instrumenten aus dem islamischen Kulturkreis sind auffällig. Tycho Brahes Meßgeräte markieren einen großen Fortschritt in der Entwicklung astronomischer Instrumente und Meßtechniken und bilden die Grundlage für den weiteren Fortschritt der Positionsastronomie und der damit verbundenen Tabellenwerke. Die Nachwirkungen sind bis ins 17. und 18. Jahrhundert nachweisbar.

Wolfschmidt, Gudrun

276

Influence of postoperative enteral nutrition on postsurgical infections.  

PubMed Central

BACKGROUND: This study was undertaken to test the hypothesis that early enteral nutrition might reduce the incidence of serious complications after major abdominal surgery. METHODS: In a randomised double blind prospective trial 30 patients received Nutri-drink and 30 patients received placebo through a nasoduodenal feeding tube. On the day of operation the patients were given median 600 ml of either nutrition or placebo, 60 ml per hour. On the first postoperative day the patients received either 1000 ml (median) of nutrition or placebo, on day 2 1200 ml (median) nutrition, 1400 ml placebo, on day 3 1000 ml (median) nutrition, 1150 ml placebo, and on day 4 1000 ml (median) nutrition, 800 ml placebo. All patients were followed up for 30 days by the same investigator. RESULTS: The two groups were similar with regard to nutritional status and type of operation. The rate of postoperative infectious complications was significantly lower in the nutrition group, two of 30 compared with 14 of 30 in the placebo group (p = 0.0009). CONCLUSION: Early enteral nutrition given to patients after major abdominal surgery results in an important reduction in infectious complications. PMID:9038665

Beier-Holgersen, R; Boesby, S

1996-01-01

277

The effects of early postoperative radiation on vascularized bone grafts  

SciTech Connect

The effects of early postoperative radiation were assessed in free nonvascularized and free vascularized rib grafts in the canine model. The mandibles of one-half of the dogs were exposed to a cobalt 60 radiation dose of 4080 cGy over a 4-week period, starting 2 weeks postoperatively. The patency of vascularized grafts was confirmed with bone scintigraphy. Histological studies, including ultraviolet microscopy with trifluorochrome labeling, and histomorphometric analyses were performed. Osteocytes persist within the cortex of the vascularized nonradiated grafts to a much greater extent than in nonvascularized, nonradiated grafts. Cortical osteocytes do not persist in either vascularized or nonvascularized grafts subjected to radiation. New bone formation is significantly retarded in radiated grafts compared with nonradiated grafts. Periosteum and endosteum remained viable in the radiated vascularized grafts, producing both bone union and increased bone turnover, neither of which were evident to any significant extent in nonvascularized grafts. Bone union was achieved in vascularized and non-vascularized nonradiated bone. In the radiated group of dogs, union was only seen in the vascularized bone grafts.

Evans, H.B.; Brown, S.; Hurst, L.N. (Division of Plastic and Reconstructive Surgery, University of Western Ontario, London (Canada))

1991-06-01

278

Pharmacokinetics, intraoperative effect and postoperative analgesia of tramadol in cats.  

PubMed

Tramadol is a synthetic codeine analogue used as an analgesic in human and veterinary medicine, but not approved for use in cats. Tramadol (2 mg/kg) was administered intravenously (IV) as preoperative analgesic in 12 cats (6 males) undergoing surgical gonadectomy. The pharmacokinetic profile of the drug and its O-desmethyl metabolite were determined in 8 animals (4 males), while intraoperative effects and postoperative analgesia, estimated by subjective pain score (0-24), were evaluated in all. Mean intraoperative isoflurane consumption was reduced, but hypoventilation was not observed. Sex-related differences were not observed, particularly in terms of postoperative analgesia: rescue analgesic was never administered. Concentrations of the active O-desmethyl metabolite were persistently high in all the animals. Considering the results obtained in this study, tramadol, at the dose of 2 mg/kg IV, did not produce any evident intraoperative cardiorespiratory side effects and with additional investigation may prove to be an appropriate intraoperative analgesic in cats undergoing gonadectomy. PMID:20708759

Cagnardi, P; Villa, R; Zonca, A; Gallo, M; Beccaglia, M; Luvoni, G C; Vettorato, E; Carli, S; Fonda, D; Ravasio, G

2011-06-01

279

Prophylactic effectiveness of budesonide inhalation in reducing postoperative throat complaints.  

PubMed

Postoperative sore throat (POST) is one of the main postoperative complaints. This study was to evaluate the efficacy of budesonide inhalation suspension (BIS) in reducing the incidence and severity of POST. One hundred and twenty patients scheduled for thyroid surgery with general anesthesia were enrolled and randomized into three groups. Group A received 200 mcg BIS 10 min prior to the tracheal intubation and received the same treatment 6 and 24 h after extubation. Group B received 200 mcg BIS 6 and 24 h after extubation. Control group received the same scheduled treatment as Group A, but the BIS was replaced with 2 ml normal saline. The patients were evaluated for sore throat and hoarseness 1, 24 and 48 h after extubation. The status of laryngopharynx was also recorded. There was no statistically significant difference in the incidence of sore throat among three groups. However, hoarseness occurred significantly less frequently in Group A (P < 0.05). One hour after extubation, Group A exhibited significantly less severe sore throat and hoarseness compared to the other two groups (P < 0.05), which disappeared 24 h later. The mucositis scores of laryngopharynx at 1, 24 and 48 h post-extubation were significantly lower in Group A (P < 0.05). BIS can reduce the incidence and severity of the POST prophylactically. PMID:24487458

Chen, Yan-Qing; Li, Ji-Ping; Xiao, Jie

2014-06-01

280

Modified Mandibulotomy Technique to Reduce Postoperative Complications: 5-Year Results  

PubMed Central

Purpose To review the 5-year outcomes of our modified mandibulotomy technique. Retrospective review of a tertiary level oral cancer center. Materials and Methods During a 5-year period, 30 patients who had a uniform surgical technique consisting of a lower lip-splitting, modified stair-step osteotomy with thin saw blade and osteotome after plate-precontouring and combination fixation with monocortical osteosynthesis (miniplate) and bicortical osteosynthesis (maxiplate and bicortical screws), with at least 14 months postoperative follow-up, were selected and reviewed retrospectively. Results There were 8 women and 22 men with an average age of 56.5 years. All the patients involved malignancies were squamous cell carcinoma. The main primary sites of the those who underwent a mandibulotomy were the tonsil, the base of tongue, the oral tongue, the retromolar pad area, and others. Others included buccal cheek, floor of mouth, and soft palate. 23 patients received postoperative radiation therapy, and among whom 8 patients also received chemotherapy. Total four (13%) mandibulotomy-related complications occurred, only two (6.7%) requiring additional operation under general anesthesia. Conclusion Our modified mandibulotomy meets the criteria for an ideal mandibulotomy technique relatively well because it requires no intermaxillary fixation, can precise preserve the occlusion in a precise way, allows early function, requires no secondary procedures, and has few complications. PMID:23918577

Na, Hye-Young; Choi, Eun-Joo; Kim, Hyung Jun; Cha, In-Ho

2013-01-01

281

Effect of Pregabalin and Dexamethasone on Postoperative Analgesia after Septoplasty  

PubMed Central

Objectives. The aim of this study was to explore effect of a combination of pregabalin and dexamethasone on pain control after septoplasty operations. Methods. In this study, 90 patients who were scheduled for septoplasty under general anesthesia were randomly assigned into groups that received either placebo (Group C), pregabalin (Group P), or pregabalin and dexamethasone (Group PD). Preoperatively, patients received either pregabalin 300?mg one hour before surgery, dexamethasone 8?mg intravenously during induction, or placebo according to their allocation. Postoperative pain treatment included tramadol and diclofenac sodium 30 minutes before the end of the operation. Numeric rating scale (NRS) for pain assessment, side effects, and consumption of tramadol, pethidine, and ondansetron were recorded. Results. The median NRS score at the postoperative 0 and the 2nd?h was significantly higher in Group C than in Group P and Group PD (P ? 0.004 for both). The 24?h tramadol and pethidine, consumptions were significantly reduced in Groups P and PD compared to Group C (P < 0.001 and P < 0.001). The incidence of blurred vision was significantly higher in Group PD compared to Group C within both 0–2?h and 0–24?h periods (P = 0.002 and P < 0.001, resp.). Conclusions. We conclude that administration of 300 mg pregabalin preoperatively may be an adequate choice for pain control after septoplasty. Addition of dexamethasone does not significantly reduce pain in these patients. PMID:24876957

Demirhan, Abdullah; Akkaya, Akcan; Tekelioglu, Umit Yasar; Apuhan, Tayfun; Bilgi, Murat; Yurttas, Veysel; Bayir, Hakan; Yildiz, Isa; Gok, Uzeyir; Kocoglu, Hasan

2014-01-01

282

Untersuchungen über die Eigenschaften der Beeren und Blätter von süßen und bitteren Ebereschen ( Sorbus aucuparia L.)  

Microsoft Academic Search

1.Im Zusammenhang mit züchterischen Arbeiten wurden serienmäßige Untersuchungen über die Eigenschaften süßfrüchtiger und gewöhnlicher bitterer Ebereschen durchgeführt. Die mährische Süße Eberesche (var.moravica) unterscheidet sich vor allem durch bedeutend größere Beeren und Fruchtstände, sowie wesentlich höhere Zucker- und Vitamin-C-Gehalte der Früchte von der bitteren Form. Auch der Gehalt an Fruchtsäure zeigt im Durchschnitt eine Steigerung gegenüber der Normalform. Bei der noch

Wolfgang R. Müller-Stoll; Klaus Michael

1949-01-01

283

Die Resistenz des Mycobacterium tuberculosis gegen Ethionamid, Thiosemicarbazon und Isoxyl und ihre Beziehungen zueinander  

Microsoft Academic Search

Zusammenfassung An Stämmen von 522 Lungentuberkulösen wurde in 1596 Testungen die Empfindlichkeit gegen Isoxyl, Thiosemicarbazon und Ethionamid gleichzeitig geprüft. In diesem Routinematerial betrug die Häufigkeit einer Thiosemicarbazonresistenz 8,2%, der Isoxylresistenz 10,1% und der Ethionamidresistenz 6,5%. Die Kreuzresistenz zwischen Thiosemicarbazon und Ethionamid ist sehr häufig. In 75% war die Isoxylresistenz mit einer Thiosemicarbazonresistenz gekoppelt. Eine primäre Resistenz gegen Isoxyl wurde in

H. Eule; E. Werner

1967-01-01

284

20 Kombination von C++ und Java 20-1(368) 20 Kombination von C++ und Java  

E-print Network

20 Kombination von C++ und Java 20-1(368) 20 Kombination von C++ und Java Inhalt 20.1 Java Native Interface (JNI) 20.1.1 C++-Funktionen aus Java aufrufen 20.1.2 Java-Funktionen aus C++ aufrufen 20.2 gcj und das Compiled Native Interface (CNI) 20.2.1 C++-Funktionen aus Java aufrufen 20.2.2 Java-Funktionen aus

Arndt, Holger

285

20 Kombination von C++ und Java 20-1 20 Kombination von C++ und Java  

E-print Network

20 Kombination von C++ und Java 20-1 20 Kombination von C++ und Java Inhalt 20.1 Java Native Interface (JNI) 20.1.1 C++-Funktionen aus Java aufrufen 20.1.2 Java-Funktionen aus C++ aufrufen 20.2 gcj und das Cygnus Native Interface (CNI) 20.2.1 C++-Funktionen aus Java aufrufen 20.2.2 Java-Funktionen aus C

Arndt, Holger

286

Single dose oral paracetamol (acetaminophen) for postoperative pain in adults  

PubMed Central

Background This is an updated version of the original Cochrane review published in Issue 1, 2004 - this original review had been split from a previous title on ‘Single dose paracetamol (acetaminophen) with and without codeine for postoperative pain’. The last version of this review concluded that paracetamol is an effective analgesic for postoperative pain, but additional trials have since been published. This review sought to evaluate the efficacy and safety of paracetamol using current data, and to compare the findings with other analgesics evaluated in the same way. Objectives To assess the efficacy of single dose oral paracetamol for the treatment of acute postoperative pain. Search methods We searched The Cochrane Library, MEDLINE, EMBASE, the Oxford Pain Relief Database and reference lists of articles to update an existing version of the review in July 2008. Selection criteria Randomised, double-blind, placebo-controlled clinical trials of paracetamol for acute postoperative pain in adults. Data collection and analysis Two review authors independently assessed trial quality and extracted data. Area under the “pain relief versus time” curve was used to derive the proportion of participants with paracetamol or placebo experiencing at least 50% pain relief over four to six hours, using validated equations. Number-needed-to-treat-to-benefit (NNT) was calculated, with 95% confidence intervals (CI). The proportion of participants using rescue analgesia over a specified time period, and time to use, were sought as measures of duration of analgesia. Information on adverse events and withdrawals was also collected. Main results Fifty-one studies, with 5762 participants, were included: 3277 participants were treated with a single oral dose of paracetamol and 2425 with placebo. About half of participants treated with paracetamol at standard doses achieved at least 50% pain relief over four to six hours, compared with about 20% treated with placebo. NNTs for at least 50% pain relief over four to six hours following a single dose of paracetamol were as follows: 500 mg NNT 3.5 (2.7 to 4.8); 600 to 650 mg NNT 4.6 (3.9 to 5.5); 975 to 1000 mg NNT 3.6 (3.4 to 4.0). There was no dose response. Sensitivity analysis showed no significant effect of trial size or quality on this outcome. About half of participants needed additional analgesia over four to six hours, compared with about 70% with placebo. Five people would need to be treated with 1000 mg paracetamol, the most commonly used dose, to prevent one needing rescue medication over four to six hours, who would have needed it with placebo. Adverse event reporting was inconsistent and often incomplete. Reported adverse events were mainly mild and transient, and occurred at similar rates with 1000 mg paracetamol and placebo. No serious adverse events were reported. Withdrawals due to adverse events were uncommon and occurred in both paracetamol and placebo treatment arms. Authors’ conclusions A single dose of paracetamol provides effective analgesia for about half of patients with acute postoperative pain, for a period of about four hours, and is associated with few, mainly mild, adverse events. PMID:18843665

Toms, Laurence; McQuay, Henry J; Derry, Sheena; Moore, R Andrew

2014-01-01

287

Forschen und Wissen info52 Die Agentur fr Erwachsenen-und Weiter-  

E-print Network

Ratten: Auswirkungen auf Kommunikation, Sozialverhal- ten, Motivation und Motorik". Die Tourette Syndrome selectively bred for deficient prepulse inhibition, an endophenotype for Tourette's syndrome". Kontakt: Ursula

Manstein, Dietmar J.

288

Nachweis von Erdnuss- und Sesamallergenen mittels PCR und Real-time PCR.  

E-print Network

??Aktuelle Studien berichten, dass die Prävalenz von Lebensmittelallergien in industrialisierten Ländern steigt. Da die Aufnahme von Erdnüssen und Sesam bei sensibilisierten Personen oft schwere allergische… (more)

Rilling, Kristina

2010-01-01

289

Speziesdifferenzierung in Milch- und Sojamilchprodukten mittels Real-time PCR und PCR.  

E-print Network

??Die Authentizitätsbestimmung von Lebensmitteln ist in den letzten Jahren zu einer treibenden Kraft für die Entwicklung DNA-basierter Methoden zur Aufdeckung von Verfälschungen und fehlerhaften Deklarationen… (more)

Kern, Carola Christina

2010-01-01

290

Immunphänotypisierung von Neutrophilen Granulozyten und NK-Zellen bei Sepsis-, HLH- und Tumorpatienten.  

E-print Network

??Der septische Formenkreis, Tumorerkrankungen und die Hämophagozytische Lymphohistiozytose (HLH) gehören nach wie vor zu den großen Herausforderungen im Klinikalltag. Eine analytische Möglichkeit kann hierbei die… (more)

Möhrle, Stephanie

2011-01-01

291

Probable risk factors for postoperative delirium in patients undergoing spinal surgery  

Microsoft Academic Search

Postoperative delirium and its risk factors had been widely reported in several kinds of surgeries; however, there is only\\u000a one known article relative to postoperative delirium in spinal surgery. We retrospectively examined the incidence of postoperative\\u000a delirium and the probable risk factors in patients undergoing spinal surgery in our hospital, with the same aged non-delirium\\u000a patients as controls, over a

Rui Gao; Zhi-zhou Yang; Ming Li; Zhi-cai Shi; Qiang Fu

2008-01-01

292

Development of postoperative delirium in relation to a room change in the general surgical unit  

Microsoft Academic Search

To analyze the relationship between the development of postoperative delirium and a change of the patient's room, 1,006 cases of patients who had undergone surgery with general anesthesia were reviewed. Postoperative delirium developed in 84 (8.3%) cases. On the basis of symptomatic features, postoperative delirium was divided into four types: (1) excitement type, (2) excitement-hallucination type, (3) hallucination type, and

Shinichi Tsutsui; Masayuki Kitamura; Hidefumi Higashi; Hiroshi Matsuura; Shimako Hirashima

1996-01-01

293

Lack of analgesic efficacy of oral ?-9-tetrahydrocannabinol in postoperative pain  

Microsoft Academic Search

We have evaluated the efficacy of ?-9-tetrahydrocannabinol (?-9-THC), the main psychoactive constituent of cannabis, in postoperative pain. In a randomized double-blind, placebo-controlled, single-dose trial, we investigated 40 women undergoing elective abdominal hysterectomy. Randomization took place when postoperative patient-controlled analgesia was discontinued on the second postoperative day. When patients requested further analgesia, they received a single, identical capsule of either oral

Donal J Buggy; Lynn Toogood; Shelagh Maric; Paul Sharpe; David G Lambert; David J Rowbotham

2003-01-01

294

Laparoscopic Nephrectomy: Assessment of Morcellation versus Intact Specimen Extraction on Postoperative Status  

Microsoft Academic Search

PurposeWe compared pathological evaluation and postoperative recovery in patients undergoing transperitoneal laparoscopic nephrectomy at our institution with morcellated vs intact specimen extraction.

FERNANDO HERNANDEZ; KOON H. RHA; PETER A. PINTO; FERNANDO J. KIM; NICHOLAS KLICOS; THERESA Y. CHAN; LOUIS R. KAVOUSSI; THOMAS W. JARRETT

2003-01-01

295

Herzschrittmachertherapie ohne Aggregat und ohne Kabel  

E-print Network

Medtronic Wearable Pacemaker operiert von W. Lillehei Minneapolis 1957/58 #12;Christian Veltmann Klinik für Kardiologie und Angiologie veltmann.christian@mhhannover.de ,,Leadless Pacer" Nanostim (SJM) Micra (Medtronic

Manstein, Dietmar J.

296

Einfhrungsveranstaltungen der Agrar-und Umweltwissenschaftlichen Fakultt  

E-print Network

- Agrar- und Umweltwissenschaftliche Fakultät | Universität Rostock | Justus-von-Liebig-Weg 6 | 18059 Rostock Programm 07.10.2013 13:00 Uhr Gemeinsames Grillen der Erstsemesterstudenten Campus-Innenhof Justus-von-Liebig

Wolkenhauer, Olaf

297

Universittsmedizin Gttingen Publikationen und Hochschulschriften 2010  

E-print Network

in larvae of Xenopus laevis. J Neurosci (Internet-Ausgabe), 30(26): 8965-73. 3. Cordiglieri C, Odoardi F. Pallesen L, Dr. med., Reaktionen der olfaktorischen Sensorneurone von Xenopus-laevis-Larven auf Di- und

Gollisch, Tim

298

Über das Zusammenwirken von Jarowisation und Photoperiodismus  

Microsoft Academic Search

Zusammenfassung BeiSinapis alba, Agrostemma Githago und vielleicht auch Sommerrübsen ist die relative Abkürzung der bis zum Blühen vergehenden Zeit durch Jarowisation um so größer, je kürzer der Tag ist.

Richard Harder; Dietrich von Denffer

1937-01-01

299

Die Entwicklung vor Leibniz und Newton  

E-print Network

orientierte Verfahren, während Pierre de Fermat und James Gregory einen eher algebraisch orien- tierten Zugang verfolgten. So wusste etwa Fermat schon vor 1640, wie man die Funktion xn integriert. In Isaac Barrows Buch

Vollmer, Heribert

300

Universittsmedizin Gttingen Publikationen und Hochschulschriften 2011  

E-print Network

somatosensorischen Cortex der Maus. Dissertation Universität Göttingen 2011. 3. Schmücker J, Dr. med., Untersuchung der Schwann-Zell-Migration und -Proliferation im peripheren sympathischen Nervensystem der Maus

Gollisch, Tim

301

Universittsmedizin Gttingen Publikationen und Hochschulschriften 2010  

E-print Network

Zellspezifikation während der Entwicklung des Vorderhirns der Maus in Abhängigkeit des Zytokins Tgf und der. Schemmel S, Dr. med., Neuronaler Zelltod in der postnatalen Entwicklung der Maus. Dissertation Universität

Gollisch, Tim

302

Das ?-Strahlenspektrum von Radium und seine Deutung  

Microsoft Academic Search

Zusammenfassung Hochprozentiges Radium wird als Carbonat auf Platindrähtchen niedergeschlagen, um lineare Strahlungsguellen für die Untersuchung der ß-Strahlen des Radiums selbst zu erhalten. Durch geeignete Behandlung werden Präparate hergestellt, die anfänglich nur 1 Prom. der Gleichgewichtsmenge Emanation enthalten und praktisch nicht emanieren. Es gelingt so, das dem Radium angehörige ß-Strahlenspektrum, bestehend aus drei Gruppen, einwandfrei festzustellen und die zugehörige Kern-?-Strahlung zu

Otto Hahn; Lise Meitner

1924-01-01

303

Universitat Konstanz Fachbereich Mathematik und Statistik  

E-print Network

empfoh- lene Tagesdosis dreier Vitamine: Vitamin C 150 mg Vitamin E 24 mg Fols¨aure 250 µg Da Herr Mayer Vitalb¨archen Vitamin C 18 mg 9 mg Vitamin E 10.3 mg 2 mg Fols¨aure 200 µg 250 µg Energiewert 323 kcal C zu decken, da er ab und zu auch eine Scheibe Zitrone zum Schnitzel i�t. Vitamin E und Fols¨aure

Dreher, Michael

304

Evolution: Treibende Kräfte in Natur und Kultur  

Microsoft Academic Search

\\u000a \\u000a Vorbemerkung Der vorliegende Text ist sozusagen die Nachschrift meines im Dezember 2007 in Dresden gehaltenen Vortrags. Ich hielt den\\u000a Vortrag im Wesentlichen in freier Rede, nur auf der Basis einiger Notizen, und schrieb den vollen Text danach. Dabei habe\\u000a ich den Vortragsstil beibehalten. Allerdings habe ich nachträglich manches hinzugefügt, den Beitrag mit ein paar Anmerkungen\\u000a versehen und einiges an zwischenzeitlich

Franz M. Wuketits; Charles Darwin

305

Globalisierung in den Bereichen Rüstungsindustrie und Militärtechnik  

Microsoft Academic Search

\\u000a Obgleich der Zerfall der Sowjetunion und die Auflösung der bipolaren Weltordnung überraschend friedlich vonstattengingen,\\u000a blieb die für die Zeit nach dem Konflikt der Supermächte erhoffte „Friedensdividende“ aus. Die neue Weltordnung zeichnete\\u000a sich vielmehr durch einen Transformationsprozess aus, in dessen Zuge die ehemals klar umrissenen Bedrohungswahrnehmungen des\\u000a Kalten Krieges verblassten, zugleich jedoch neue, fluide Risikoszenarien und ein Gefühl allgemein wachsender Unsicherheit

Frank Sauer

306

Novel multimodality endoscopic closure of postoperative esophageal fistula  

PubMed Central

INTRODUCTION Esophageal fistula following esophagectomy is associated with significant morbidity and mortality. PRESENTATION OF CASE We present the case of a 71-year-old man who underwent salvage Ivor-Lewis esophagectomy, following definitive chemoradiotherapy 1 year previously. On postoperative day 9 the patient complained of chest pain, and a CT scan demonstrated extravasation of oral contrast from the gastric conduit into the right chest. A right chest drain and fully covered esophageal stent were placed at this time. Despite these measures, after 8 weeks, the esophageal fistula persisted. Ultimately, fistula closure was achieved using an interventional radiology-guided, endoscopically placed over-the-scope clip (OTSC). The patient had no further complications and was well at 3 months follow-up. DISCUSSION The case reported herein describes this novel, combined-modality approach to esophageal fistula closure. CONCLUSION This case report demonstrates a novel, minimally invasive, multidisciplinary approach to the closure of a post-esophagectomy anastamotic leak. PMID:22943885

Markar, Sheraz R.; Koehler, Richard; Low, Donald E.; Ross, Andrew

2012-01-01

307

Single dose oral rofecoxib for acute postoperative pain in adults  

PubMed Central

Background Editor’s note: The anti-inflammatory drug rofecoxib (Vioxx) was withdrawn from the market at the end of September 2004 after it was shown that long-term use (greater than 18 months) could increase the risk of heart attack and stroke in a study of secondary prevention of adenoma recurrence. Further information is available at www.vioxx.com. Rofecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor previously licensed for treating acute and chronic pain; it was associated with fewer gastrointestinal adverse events than conventional NSAIDs. An earlier Cochrane review (Barden 2005) showed that rofecoxib is at least as effective as conventional non-steroidal anti-inflammatory drugs (NSAIDs) for postoperative pain. Objectives To assess the analgesic efficacy and adverse effects of rofecoxib in single oral doses for moderate and severe postoperative pain. Search methods We searched Cochrane CENTRAL, MEDLINE, EMBASE and the Oxford Pain Relief Database for studies to June 2009. Selection criteria Randomised, double blind, placebo-controlled trials of single dose orally administered rofecoxib in adults with moderate to severe acute postoperative pain. Data collection and analysis Two review authors independently assessed trial quality and extracted data. Pain relief or pain intensity data were extracted and converted into the dichotomous outcome of number of participants with at least 50% pain relief over 4 to 6 hours, from which relative risk and number needed to treat to benefit (NNT) were calculated. Numbers of participants using rescue medication over specified time periods, and time to use of rescue medication, were sought as additional measures of efficacy. Information on adverse events and withdrawals was collected. Main results Twenty new studies and seven from the earlier review met the inclusion criteria. Twenty-four studies were in dental surgery and three in other types of surgery. In total, 2636 participants were treated with rofecoxib 50 mg, 20 with rofecoxib 500 mg, and 1251 with placebo. The NNT for at least 50% pain relief over 4 to 6 hours with rofecoxib 50 mg was 2.2 (2.0 to 2.3) in all studies combined, 1.9 (1.8 to 2.0) in dental studies, and 6.8 (4.6 to 13) in other types of surgery. The median time to use of rescue medication was 14 hours for rofecoxib 50 mg and 2 hours for placebo. Significantly fewer participants used rescue medication following rofecoxib 50 mg than with placebo. Adverse events did not differ from placebo. Authors’ conclusions Rofecoxib 50 mg (two to four times the standard daily dose for chronic pain) is an effective single dose oral analgesic for acute postoperative pain in adults, with a relatively long duration of action. PMID:19821329

Bulley, Simon; Derry, Sheena; Moore, R Andrew; McQuay, Henry J

2014-01-01

308

Post-operative Adult Onset Tic Disorder: A Rare Presentation.  

PubMed

Tics are rapid and repetitive muscle contractions resulting in stereotype movements and vocalizations that are experienced as involuntary. Onset before 18-year is a diagnostic criterion for tic disorders. Children and adolescents may exhibit tic behaviors after a stimulus or in response to an internal urge. Tic behaviors increase during physical or an emotional stress. Adult onset tic disorders are reported by infections, drugs, cocaine, toxins, chromosomal disorders, head injury, stroke, neurocutaneous syndromes, neurodegenerative disorders and peripheral injuries. Only few cases have yet been reported having onset after surgery though surgery brings both physical and emotional stress to the patient. We report a case of a 55-year-old lady who developed tic disorder as post-operative event of cataract surgery. Our patient had a dramatic response to haloperidol which is in contrast to all earlier reports. PMID:25336779

Upadhyaya, Suneet Kumar; Raval, Chintan M; Sharma, Devendra Kumar; Vijayvergiya, Devendra Kumar

2014-10-01

309

Inflammation Induced by Perfluorocarbon Liquid: Intra- and Postoperative Use  

PubMed Central

Perfluorocarbon liquids (PFCLs) are useful and safe surgical tools in vitreoretinal surgery. The use of PFCL as a tamponade has been controversial due to the corneal toxicity, retinal infiltration, and inflammatory reaction in experimental studies. Several authors have studied in humans the anatomical and functional outcome and adverse effects of perfluorocarbon liquids used as short-, medium-, and long-term tamponade. PFCLs develop dispersion a few days after injection and droplets may move into the anterior chamber and cause corneal endothelial damage. When PFCLs are used as postoperative tamponades for more than one week, a foreign-body inflammatory reaction is observed in up to 30% of cases but such a reaction does not induce PVR, and it resolves after removal of PFCLs. Although most clinical studies have found no signs of retinal toxicity such as progressive visual acuity deterioration or macular anatomical changes, few performed ERG or retinal histological analysis. PMID:24783224

Figueroa, Marta S.; Casas, Diego Ruiz

2014-01-01

310

[Post-operative functional evaluation of accessory nerve reconstruction].  

PubMed

A nerve reconstruction was performed in 20 patients whose spinal accessory nerve was resected during total neck dissection. Re-anastomosis or a cable graft was performed between both cut ends of the accessory nerve in 14 patients (accessory nerve reconstruction group), and between the peripheral cut end of the accessory nerve and the central cut end of the cervical nerve (C2 or C3) in 6 patients (cervical/accessory nerve reconstruction group). There was no difference in the postoperative shoulder functions between the reconstruction groups, and both groups were significantly better than the group without reconstruction (n = 13), although they tended to be poorer than the nerve preservation group (n = 41). PMID:24601096

Asakura, Koji; Honma, Tomo; Keira, Takashi; Nagaya, Tomonori; Himi, Tetsuo

2014-01-01

311

Fournier's Gangrene as a Postoperative Complication of Inguinal Hernia Repair.  

PubMed

Fournier's gangrene is the necrotizing fasciitis of perianal, genitourinary, and perineal regions. Herein, we present a case of scrotal Fournier's gangrene as a postoperative complication of inguinal hernia repair. A 51-year-old male with giant indirect hernia is presented. Patient underwent inguinal hernia repair, and after an unproblematic recovery period, he was discharged. He applied to our outpatient clinic on the fifth day with swollen and painful scrotum and it turned out to be Fournier's gangrene. Polypropylene mesh was not infected. Patient recovered and was discharged after repeated debridements. Basic principles in treatment of Fournier's gangrene are comprised of initial resuscitation, broad-spectrum antibiotics therapy, and early aggressive debridement. In the management of presented case, aggressive debridement was made right after diagnosis and broad-spectrum antibiotics were given to the hemodynamically stable patient. In these circumstances, the important question is whether we could prevent occurrence of Fournier's gangrene. PMID:25506030

Dinc, Tolga; Kayilioglu, Selami Ilgaz; Sozen, Isa; Yildiz, Baris Dogu; Coskun, Faruk

2014-01-01

312

POSTOP: Postbuckled open-stiffener optimum panels, user's manual  

NASA Technical Reports Server (NTRS)

The computer program POSTOP developed to serve as an aid in the analysis and sizing of stiffened composite panels that may be loaded in the postbuckling regime, is intended for the preliminary design of metal or composite panels with open-section stiffeners, subjected to multiple combined biaxial compression (or tension), shear and normal pressure load cases. Longitudinal compression, however, is assumed to be the dominant loading. Temperature, initial bow eccentricity and load eccentricity effects are included. The panel geometry is assumed to be repetitive over several bays in the longitudinal (stiffener) direction as well as in the transverse direction. Analytical routines are included to compute panel stiffnesses, strains, local and panel buckling loads, and skin/stiffener interface stresses. The resulting program is applicable to stiffened panels as commonly used in fuselage, wing, or empennage structures. The capabilities and limitations of the code are described. Instructions required to use the program and several example problems are included.

Biggers, S. B.; Dickson, J. N.

1984-01-01

313

Prevention and management of postoperative urinary retention after urogynecologic surgery.  

PubMed

Postoperative urinary retention (POUR) is a frequent consequence of gynecologic surgery, especially with surgical correction of urinary incontinence and pelvic organ prolapse. Estimates of retention rates after pelvic surgery range from 2.5%-43%. While there is no standard definition for POUR, it is characterized by impaired bladder emptying, with an elevation in the volume of retained urine. The key to management of POUR is early identification. All patients undergoing pelvic surgery, especially for the correction of incontinence or prolapse, should have an assessment of voiding function prior to discharge. There are several ways to assess voiding function - the gold standard is by measuring a postvoid residual. Management of POUR is fairly straightforward. The goal is to decompress the bladder to avoid long-term damage to bladder integrity and function. The decision regarding when to discontinue catheter-assisted bladder drainage in the postoperative period can be assessed in an ongoing fashion by measurement of postvoid residual. The rate of prolonged POUR beyond 4 weeks is low, and therefore most retention can be expected to resolve spontaneously within 4-6 weeks. When POUR does not resolve spontaneously, more active management may be required. Techniques include urethral dilation, sling stretching, sling incision, partial sling resection, and urethrolysis. While some risk of POUR is inevitable, there are risk factors that are modifiable. Patients that are at higher risk - either due to the procedures being performed or their clinical risk factors - should be counseled regarding the risks and management options for POUR prior to their surgery. Although POUR is a serious condition that can have serious consequences if left untreated, it is easily diagnosed and typically self-resolves. Clinician awareness of the condition and vigilance in its diagnosis are the key factors to successful care for patients undergoing surgical repair. PMID:25210477

Geller, Elizabeth J

2014-01-01

314

Predictors of physical functioning in postoperative brain tumor patients.  

PubMed

A cross-sectional predictive design was used to study the relationships among recovery symptoms, mood state, and physical functioning and to identify predictors of physical functioning in patients who underwent surgery for brain tumor at the first follow-up visit (2 weeks) after hospital discharge. The sample included 88 patients who were 18 years or older, had full level of consciousness, and underwent first-time surgery for brain tumor without other adjuvant treatments from a tertiary hospital in Bangkok, Thailand. Descriptive statistics, Pearson product-moment correlation coefficient, and multiple regression were used for data analysis. The results revealed that most participants were women (75%) with an average age of 45.18 ± 11.49 years, having benign brain tumors (91%) and pathological results as meningioma (48.9%). The most common recovery symptoms were pain (mean = 3.2, SD = 2.6) and sleep disturbance (mean = 3.1, SD = 3.0). As for mood state, the problem of confusion was found the most (mean = 4.6, SD = 2.7). The physical functioning problem found the most was work aspect (mean = 66.3, SD = 13.3). Recovery symptoms had positive relationships with physical functioning and mood state (r = .406, .716; p < .01), respectively. At the same time, mood state had positive relationships with physical functioning (r = .288, p < .01). Recovery symptoms, total mood disturbance, fatigue, and vigor were statistically significant predictors of physical functioning and could explain variance of postoperative physical functioning in these patients at 2 weeks after discharge by 35%. Total mood disturbance was the strongest predictor of physical functioning followed by vigor, fatigue, and recovery symptom, respectively. Interventions to improve physical functioning in postoperative brain tumor patients during home recovery should account for not only recovery symptom management but also mood state. PMID:25565598

Tankumpuan, Thitipong; Utriyaprasit, Ketsarin; Chayaput, Prangtip; Itthimathin, Parunut

2015-02-01

315

Infantile postoperative encephalopathy: perioperative factors as a cause for concern.  

PubMed

We report on 6 infants who underwent elective surgery and developed postoperative encephalopathy, which had features most consistent with intraoperative cerebral hypoperfusion. All infants were <48 weeks' postmenstrual age and underwent procedures lasting 120 to 185 minutes. Intraoperative records revealed that most of the measured systolic blood pressure (SBP) values were <60 mm?Hg (the threshold for hypotension in awake infants according to the Pediatric Advanced Life Support guidelines) but that only 11% of the measured SBP values were <1 SD of the mean definition of hypotension (<45 mm?Hg) as reported in a survey of members of the Society for Pediatric Anesthesia in 2009. Four infants also exhibited prolonged periods of mild hypocapnia (<35 mm?Hg). One infant did not receive intraoperative dextrose. All infants developed new-onset seizures within 25 hours of administration of the anesthetic, with a predominant cerebral pathology of supratentorial watershed infarction in the border zone between the anterior, middle, and posterior cerebral arteries. Follow-up of these infants found that 1 died, 1 had profound developmental delays, 1 had minor motor delays, 2 were normal, and 1 was lost to follow-up. Although the precise cause of encephalopathy cannot be determined, it is important to consider the role that SBP hypotension (as well as hypoglycemia, hyperthermia, hyperoxia, and hypocapnia) plays during general anesthesia in young infants in the development of infantile postoperative encephalopathy. Our observations highlight the lack of evidence-based recommendations for the lower limits of adequate SBP and end-tidal carbon dioxide in anesthetized infants. PMID:24515520

McCann, Mary Ellen; Schouten, A N J; Dobija, Nicole; Munoz, Carlos; Stephenson, Lianne; Poussaint, Tina Y; Kalkman, C J; Hickey, Paul R; de Vries, Linda S; Tasker, Robert C

2014-03-01

316

Post-operative bilateral adrenal haemorrhage: A case report  

PubMed Central

INTRODUCTION Bilateral adrenal haemorrhage is a rare, but serious, illness carrying an estimated 15% mortality.1,2 The majority of cases occur in patients with acute, stressful illness, however the exact mechanism underlying adrenal haemorrhage remains unclear. This medical emergency carries significant diagnostic difficulty4 with non-specific clinical symptoms and variations in electrolyte abnormalities. Timely treatment is important as it prevents both the acute and long-term sequelae of adrenal failure. PRESENTATION OF CASE This report describes a medical emergency in a surgical patient following emergency surgery for intra-abdominal sepsis. The patient reported non-specific symptoms of confusion, mild pyrexia and vague abdominal pain during the post-operative phase, with subtle electrolyte abnormalities and a low serum cortisol suggestive of adrenal crisis. Timely medical treatment, with intravenous hydrocortisone and intensive monitoring, and appropriate medical follow-up with addition of long-term fludrocortisone resulted in a satisfactory outcome. DISCUSSION This report describes a potentially life-threatening complication of intra-abdominal sepsis with adrenal crisis secondary to bilateral adrenal haemorrhage. In particular, this case highlights the diagnostic difficulty in such surgical patients due to vague symptoms and, in this case, the presence of a presentation variant with acute hyponatraemia and normal potassium. CONCLUSION This case highlights the importance of awareness of both the symptoms and signs and variation in electrolyte profile when assessing surgical patients post-operatively. In addition, this case highlights the benefit of early recognition and initiation of treatment and the importance of follow-up as long-term medical management is often required to prevent further relapse. PMID:25437659

McNicol, R.E.; Bradley, A.; Griffin, J.; Duncan, G.; Eriksen, C.A.; Guthrie, G.J.K.

2014-01-01

317

Preventive Effect of Tamsulosin on Postoperative Urinary Retention  

PubMed Central

Purpose To investigate the prophylactic effect of Tamsulosin, a super-selective alpha-1a adrenergic blocking agent, on the development of urinary retention in men undergoing elective inguinal herniorrhaphy. Materials and Methods From May 2010 through November 2011, a total of 80 males who underwent elective inguinal herniorrhaphy in a university hospital were included in this study. Patients were randomly assigned to one of two groups. In group one (control), the patients were given two doses of placebo orally, 6 hours before surgery and 6 to 12 hours after surgery. Patients in group two were given 0.4 mg of Tamsulosin orally in the same manner as the placebo. All patients were closely followed for 24 hours post-operatively, and any voiding difficulties or urinary retention was recorded. Results There were 40 patients in group one (control group) and 40 patients in group two (Tamsulosin group). The patients' mean age was 64 years. In group one, 6 patients and in group two, 1 patient required catheterization. Thus, 15% of patients in group I and 2.5% of patients in group II had urinary retention. The difference in the requirement for catheterization was statistically significant (p=0.04). The technique of herniorrhaphy, the side of the body in which the hernia was located, the type of anesthesia, the duration of the surgery, and the severity of pre-operative urinary symptoms had no significant effect on the incidence of urinary retention. Conclusions The use of perioperative Tamsulosin represents an effective strategy to reduce the risk of post-operative urinary retention following inguinal herniorrhaphy. PMID:22741052

Mohammadi-Fallah, Mohammadreza; Tayyebi-Azar, Ali

2012-01-01

318

Attacking Postoperative Metastases using Perioperative Oncolytic Viruses and Viral Vaccines  

PubMed Central

Surgical resection of solid primary malignancies is a mainstay of therapy for cancer patients. Despite being the most effective treatment for these tumors, cancer surgery has been associated with impaired metastatic clearance due to immunosuppression. In preclinical surgery models and human cancer patients, we and others have demonstrated a profound suppression of both natural killer (NK) and T cell function in the postoperative period and this plays a major role in the enhanced development of metastases following surgery. Oncolytic viruses (OV) were originally designed to selectively infect and replicate in tumors, with the primary objective of directly lysing cancer cells. It is becoming increasingly clear, however, that OV infection results in a profound inflammatory reaction within the tumor, initiating innate and adaptive immune responses against it that is critical for its therapeutic benefit. This anti-tumor immunity appears to be mediated predominantly by NK and cytotoxic T cells. In preclinical models, we found that preoperative OV prevents postoperative NK cell dysfunction and attenuates tumor dissemination. Due to theoretical safety concerns of administering live virus prior to surgery in cancer patients, we characterized safe, attenuated versions of OV, and viral vaccines that could stimulate NK cells and reduce metastases when administered in the perioperative period. In cancer patients, we observed that in vivo infusion with oncolytic vaccinia virus and ex vivo stimulation with viral vaccines promote NK cell activation. These preclinical studies provide a novel and clinically relevant setting for OV therapy. Our challenge is to identify safe and promising OV therapies that will activate NK and T cells in the perioperative period preventing the establishment of micrometastatic disease in cancer patients. PMID:25161958

Tai, Lee-Hwa; Auer, Rebecca

2014-01-01

319

Positionsbestimmung des Unternehmens: Interne und externe Analyse  

NASA Astrophysics Data System (ADS)

Die Initiierung und Lenkung von Maßnahmen zur integrierten Modernisierung zielen auf die Verbesserung der Wettbewerbsfähigkeit eines Unternehmens ab. Damit diese Maßnahmen zielgerichtet die Wettbewerbsfähigkeit verbessern können, ist Wissen über die bestehende Wettbewerbsfähigkeit sowie über die bestehenden Fähigkeiten eine zentrale Voraussetzung. Eine zielgerichtete Auswahl problemadäquater Maßnahmen zur Verbesserung der Wettbewerbsfähigkeit bedarf daher im Vorfeld einer Bewertung der aktuellen Situation des Unternehmens im Sinne einer Positionsbestimmung. Erst wenn die internen Stärken und Schwächen sowie die externen Chancen und Risiken identifiziert sind, kann ein ganzheitliches Bild von der Position eines Unternehmens in seiner Umwelt gewonnen werden. Auf Basis der Kenntnisse über die Position des Unternehmens können anschließend zielgerichtet Maßnahmen ausgewählt werden, die einen Beitrag zur Verbesserung der Wettbewerbsfähigkeit des Unternehmens haben. Damit kommt der Positionsbestimmung als initialer Schritt des Prozesses der strategischen Unternehmensplanung eine zentrale Bedeutung im Rahmen der integrierten Modernisierung zu. Erfolgt die Auswahl von Maßnahmen ohne eine vorherige Positionsbestimmung, also lediglich auf Basis drängender Probleme, so besteht die Gefahr einer unbedachten und nur auf das "hier und heute“ bezogenen Schwerpunktbildung ohne Berücksichtigung der mittel- und langfristigen Ziele des Unternehmens.

Bergmann, Lars; Crespo, Isabel; Portmann, Stefan

320

Die Editionsgeschichte der Werke von Marx und Engels in Frankreich und ihr Neubeginn mit der  

E-print Network

Editionsarbeit gezogen. 1 Siehe Karl Marx: Critique du programme de Gotha. Une e´dition nouvelle pre´pare´e parDie Editionsgeschichte der Werke von Marx und Engels in Frankreich und ihr Neubeginn mit der Grande E´dition Marx et Engels (GEME) Kolja Lindner Seit April 2008 liegt mit der Neuübersetzung der

Boyer, Edmond

321

Gegen die Wissenschaft Fußspuren Fossilien Großsäuger und Saurier Anmerkungen und Literatur  

Microsoft Academic Search

Waren Menschen und Dinosaurier Zeitgenossen? Gibt es Zeugnisse in der Erdgeschichte, die eine solche Koexistenz belegen? In der spekulativen Literatur finden sich immer wieder solche Indizien, aber belegen sie wirklich, daß es Menschen und Dinosaurier zur gleichen Zeit gab, belegen sie gar einen Besuch oder Eingriff Außerirdischer in unsere Evolution?( 1) Diese Frage läßt sich nach dem heutigen Stand der

Darwins Irrtum; Klaus Richter

2009-01-01

322

Chancen und Risiken des Schrumpfens und warum es so schwer ist, darüber zu diskutieren  

Microsoft Academic Search

Die Bevölkerung Deutschlands wird älter, heterogener und sie wird weniger. Damit sind in der öffentlichen Diskussion Katastrophenszenarien verbunden, die an die düsteren Prophezeiungen von Thomas Malthus erinnern, nur dass Malthus das Gegenteil, nämlich ein übermäßiges Wachstum der Bevölkerung befürchtete. Historisch ist Schrumpfen nichts Neues: Das Spanien des 18. und 19. Jahrhunderts war eine schrumpfende Gesellschaft. Rom, eine Millionenmetropole in der

Walter Siebel

2009-01-01

323

Fachstudien-und Prfungsordnung fr den Masterstudien-gang Economics der Rechts-und Wirtschaftswissenschaftli-  

E-print Network

Fachstudien- und Prüfungsordnung für den Masterstudien- gang Economics der Rechts- und Fachprüfungsordnung für den forschungsorientierten konsekutiven Masterstudien- gang ,,Economics" mit dem Abschluss Studiengang, 4. insbesondere ein Bachelorabschluss in einem ingenieurwissenschaftlichen Studien- gang, 5

Fiebig, Peter

324

Herstellung von Chitosan und einige Anwendungen  

NASA Astrophysics Data System (ADS)

1. Die Deacetylierung von crabshell - Chitosan führte gleichzeitig zu einem drastischen Abfall der mittleren viscosimetrischen Molmasse ( Mv), insbesondere wenn die Temperatur und die Konzentration an NaOH erhöht werden. Diese Parameter beeinflussten jedoch nicht den Grad der Deacetylierung (DD). Wichtig ist jedoch die Quelle des Ausgangsmaterials: Chitin aus Pandalus borealis ist ein guter Rohstoff für die Herstellung von Chitosan mit niedrigem DD und gleichzeitig hoher mittlerer Mv, während Krill-Chitin (Euphausia superba) ein gutes Ausgangsmaterial zur Herstellung von Chitosan mit hohem DD und niedrigem Mv ist. Chitosan, das aus Insekten (Calliphora erythrocephala), unter milden Bedingungen (Temperatur: 100°C, NaOH-Konzentration: 40 %, Zeit: 1-2h ) hergestellt wurde, hatte die gleichen Eigenschaften hinsichtlich DD und Mv wie das aus Krill hergestellte Chitosan. Der Bedarf an Zeit, Energie und NaOH ist für die Herstellung von Insekten-Chitosan geringer als für crabshell-Chitosan vergleichbare Resultaten für DD und Mv. 2. Chitosan wurde durch den Schimmelpilz Aspergillus fumigatus zu Chitooligomeren fermentiert. Die Ausbeute beträgt 25%. Die Chitooligomere wurden mit Hilfe von HPLC und MALDI-TOF-Massenspektrmetrie identifiziert. Die Fermentationsmischung fördert die Immunität von Pflanzen gegen Bakterien und Virusinfektion. Die Zunahme der Immunität schwankt jedoch je nach System Pflanze-Pathogen. Die Fermentation von Chitosan durch Aspergillus fumigatus könnte eine schnelle und billige Methode zur Herstellung von Chitooligomeren mit guter Reinheit und Ausbeute sein. Eine partiell aufgereinigte Fermentationsmischung dieser Art könnte in der Landwirtschaft als Pathogeninhibitor genutzt werden. Durch kontrollierte Fermentation, die Chitooligomere in definierter Zusammensetzung (d.h. definierter Verteilung des Depolymerisationsgrades) liefert, könnte man zu Mischungen kommen, die für die jeweilige Anwendung eine optimale Bioaktivität besitzen. 3. Die aus Chitosan-Dispersionen hergestellten MCChB-Filme weisen bessere mechanische Eigenschaften (Bruchfestigkeit, Dehnung) und eine höhere Wasseraufnahmefähigkeit auf als Filme, die nach herkömmlichen Methoden aus sauerer Lösung hergestellt werden. Die Einführung von Proteinen ändert die mechanischen Eigenschaften der MCChB-Filme abhängig von der Art, der Proteine sowie des DD und der Mv des eingesetzte Chitosan. Die Zugabe von Protein beschleunigt den biologischen Abbau der MCChB-Filme. Aus den untersuchten MCChB-Filmen mit Proteinzusatz können leichte, reißfeste und dennoch elastische Materialen hergestellt werden. 4. Mit Hilfe von MCChB-Dispersion kann Papier modifiziert werden. Dadurch werden die mechanischen Eigenschaften verbessert und die Wasseraufnahme wird verringert. Die Zugabe von Proteinen verringert das Wasseraufnahmevermögen noch weiter. Ein geringes Wasseraufnahmevermögen ist der bedeutendste Faktor bei der Papierherstellung. Auch Papier, das mit einem MCChB-Protein-Komplexe modifiziert wurde, zeigt gute mechanische Eigenschaften. 5. Wird Chitosan durch unmittelbare Einführung von MCChB auf Cellulose-Fasern aufgebracht, so erhält man eine netzartige Struktur, während durch Ausfällung aufgebrachtes Chitosan eine dünne Schicht auf den Cellulose-Fasern bildet. Die netzartige Struktur erleichtert die Bioabbaubarkeit, während die Schichtstruktur diese erschwert. 6. Die guten mechanischen Eigenschaften, die geringe Wasseraufnahmefähigkeit und die mit Cellulose vergleichbare Bioabbaubarkeit von Papier, das mit MCChB modifiziert wurde, lassen MCChB für die Veredlung von Papier nützlich erscheinen. 1. Deacetylation of the crustacean chitosan causes drastically decrease in the Mv with increasing reaction temperature and time as well as the concentration of sodium hydroxide. However, the DD are relatively less affected. Pandalus borealis is a good source for production of chitosan having high Mv and low DD, whereas chitosan of medium to low Mv can ideally be prepared using krill chitin. Insect chitosan is prepared under milder condition a

Struszczyk, Marcin Henryk

2001-05-01

325

Georg Faustus – Leben und Legende  

E-print Network

://www.historicum.net/no_cache/persistent/artikel/7114/. Open Access version: http://kuscholarworks.ku.edu/dspace/. 1 P le a se n o te t h a t th is is a n a u th o r- p ro d u ce d P D F o f a n a rt ic le a cc ep te d f o r p u b lic a ti o n f o llo w in g p ee r re vi ew...) 12. November 2009 (english version?) * 1466 (?) in Helmstadt, † um 1540; Astrologe, Wahrsager und Bezugsperson der Faustlegende, oft als Johann Faust bezeichnet 1. Kurzbiografie Es existieren nur wenige verlässliche Quellen über den...

Baron, Frank

2009-01-01

326

Mol-Gastronomie Granulare Fleischgerichte und molekulares Kleben  

NASA Astrophysics Data System (ADS)

Buletten, Fleischküchle oder Kebabs, Köstlichkeiten aus gehacktem Fleisch bestimmter Körnung, finden sich in allen Kulturen. Physikalisch ein großes Problem, denn zu Tisch dürfen diese Gebilde nicht auseinander brechen und zerfallen. Für ausreichend Bindung und Klebung muss also gesorgt werden.

Vilgis, Thomas A.

2005-09-01

327

Rudolf Lindau Die Freundschaft, welche Wilson und Irwing ver-  

E-print Network

chinesischen Seidenver- käufer, die gleichzeitig die Hauptkäufer von indischem Opium und englischen Meilen weit in das Innere, um dort Opium und Waffen gegen Seide einzutauschen. Es war eine kurze Zeit, wo

Prodinger, Helmut

328

Mathematik II fur Informatiker, Compu-tervisualisten, Wirtschaftsinformatiker und  

E-print Network

Ingenieurinformatiker SS 2011 Otto-von-Guericke-Universit¨at Magdeburg Prof. Dr. Wolfgang Willems, Dr. Michael H) Berechnen Sie den Wert von I und vergleichen Sie diesen mit den unter (a) und (b) erhaltenen N

Willems, Wolfgang

329

Einfluss von UVA-Strahlung auf neuroendokrine und psychologische Parameter.  

E-print Network

??Die UVA-Probanden (n=42) erhielten sechs Bestrahlungen. Serotonin-, Melatonin-, ?-Endorphin- und Met-Enkephalin- Bestimmungen wurden vor der ersten (t1), 20 Minuten nach der ersten (t2) und 24h… (more)

Vojvodic-Mayer, Mirjana

2006-01-01

330

Untersuchung zur Klassifizierung, Identifizierung und Differenzierung von Yersinia Arten.  

E-print Network

??Zur Identifizierung und Differenzierung von Y. pestis wurden mehrere PCR-Methoden entwickelt sowie eine Multiplex-PCR zur gleichzeitigen Identifizierung von Stämmen der Spezies Y. pestis und Y.… (more)

Amann, Sabine

2007-01-01

331

Postoperative Pain in Children: Developmental and Family Influences on Spontaneous Coping Strategies  

Microsoft Academic Search

Despite advances in pharmacological approaches to pain control, most children who undergo surgery continue to experience moderate to severe postoperative pain. Children and their parents are forced to rely on personal resources to cope with this severe stressor. This study examined children and parents' reactions to post-operative pain, including stress appraisal and cognitive-behavioural coping processes from a developmental perspective. Sixty

SUSAN M. BENNETT-BRANSON; KENNETH D. CRAIG

1993-01-01

332

Pain. Author manuscript A patient-based national survey on postoperative pain management in  

E-print Network

Pain. Author manuscript Page /1 18 A patient-based national survey on postoperative pain management.fletcher@rpc.aphp.fr> Abstract We carried out a national survey on postoperative pain (POP) management in a representative sample pain, evaluation, treatment and side effects. A local consultant provided information about POP

Boyer, Edmond

333

Use of Epidural Morphine for Control of Postoperative Pain in Selective Dorsal Rhizotomy for Spasticity  

Microsoft Academic Search

Postoperative pain control can be a major problem after selective dorsal rhizotomy for the treatment of spasticity. We report the use of epidural morphine delivered via a catheter placed at surgery for postoperative analgesia in 28 consecutive patients undergoing this procedure. Pain was well controlled using this technique, and no patients required concomitant parenteral analgesia. There were no instances of

Mary Louise Sparkes; Alan S. Klein; Ann-Christine Duhaime; Parker Mickle

1989-01-01

334

Risk factors for postoperative hypoxemia in patients undergoing Stanford A aortic dissection surgery  

PubMed Central

Background The purpose of this study is to identify the risk factors for postoperative hypoxemia in patients with Stanford A aortic dissection surgery and their relation to clinical outcomes. Methods Clinical records of 186 patients with postoperative hypoxemia in Stanford A aortic dissection were analyzed retrospectively. The patients were divided into two groups by postoperative oxygen fraction (PaO2/FiO2):hypoxemia group (N=92) and non-hypoxemia group (N=94). Results We found that the incidence of postoperative hypoxemia was 49.5%. Statistical analysis by t-test and ?2 indicated that acute onset of the aortic dissection (p=0.000), preoperative oxygen fraction (PaO2/FiO2) ?200 mmHg(p=0.000), body mass index (p=0.008), circulatory arrest (CA) time (p=0.000) and transfusion more than 3000 ml(p=0.000) were significantly associated with postoperative hypoxemia. Multiple logistic regression analysis showed that preoperative hypoxemia, CA time and transfusion more than 3000 ml were independently associated with postoperative hypoxemia in Stanford A aortic dissection. Conclusion Our results suggest that postoperative hypoxemia is a common complication in patients treated by Stanford A aortic dissection surgery. Preoperative oxygen fraction lower than 200 mmHg, longer CA time and transfusion more than 3000 ml are predictors of postoperative hypoxemia in Stanford A aortic dissection. PMID:23631417

2013-01-01

335

Prophylactic Consecutive Administration of Haloperidol Can Reduce the Occurrence of Postoperative Delirium in Gastrointestinal Surgery  

Microsoft Academic Search

Postoperative delirium has in recent years been a common complication which can interfere with the recovery of patients after surgery. Unfortunately there is still no medical procedure available which can completely prevent the occurrence of postoperative delirium. Haloperidol is a psychopharmacological agent that has been used to treat the delirium and agitation, especially in geriatric patients. To assess the effectiveness

Tetsuya Kaneko; Jianhui Cai; Takanori Ishikura; Makoto Kobayashi; Takuji Naka; Nobuaki Kaibara

336

Risk factors for postoperative delirium in patients undergoing head and neck cancer surgery  

Microsoft Academic Search

This study was carried out to determine risk factors for delirium after major head and neck cancer surgery. The postoperative experience of 38 patients who underwent major head and neck cancer surgery and were managed in the high care unit was retrospectively examined by reviewing their medical records. Delirium was defined as confusion and abnormal behavior that interfered with postoperative

K. Yamagata; K. Onizawa; H. Yusa; T. Wakatsuki; T. Yanagawa; H. Yoshida

2005-01-01

337

Risk Factors and Incidence of Postoperative Delirium in Elderly Chinese Patients  

Microsoft Academic Search

Objectives: To investigate the incidence of postoperative delirium among elderly patients and to examine the interrelationship between basic vulnerability and precipitating factors for delirium. Design and Methods: This was a prospective cohort study. Data were collected in a tertiary medical center in Taipei, Taiwan. From the 1st to the 5th postoperative day, nurses assessed patients using a confusion-screening tool. Patients

Yu-Tzu Dai; Meei-Fang Lou; Ping-Keung Yip; Guey-Shiun Huang

2000-01-01

338

Early detection of postoperative delirium and confusion in a surgical ward using the NEECHAM confusion scale  

Microsoft Academic Search

The early detection and prevention of postoperative delirium and confusion has become an important issue in surgical ward management. With the aim of determining an objective technique for early detection of delirium, 64 patients admitted to a surgical ward before surgery were examined using the NEECHAM confusion scale. On the 2nd postoperative day they were tested again and divided into

Toshiko Matsushita; Eisuke Matsushima; Michio Maruyama

2004-01-01

339

Measures of Executive Function and Depression Identify Patients at Risk for Postoperative Delirium  

Microsoft Academic Search

Background: Postoperative delirium is associated with in- creased morbidity and mortality. Preexisting cognitive impair- ment and depression have been frequently cited as important risk factors for this complication. This prospective cohort study was designed to determine whether individuals who perform poorly on preoperative cognitive tests and\\/or exhibited depres- sive symptoms would be at high risk for the development of postoperative

Nathaniel H. Greene; Deborah K. Attix; B. Craig Weldon; Patrick J. Smith; David L. McDonagh; Terri G. Monk

2009-01-01

340

Preoperative Factors Associated with Postoperative Change in Confusion Assessment Method Score in Hip Fracture Patients  

Microsoft Academic Search

Postoperative delirium is a major problem in elderly patients undergoing surgical repair of hip fracture. It is imperative to identify potentially treatable preopera- tive factors associated with the onset of postoperative delirium to optimize outcome. We sought to determine what preoperative variables are associated with post- operative delirium in geriatric patients undergoing sur- gical repair of hip fracture. In a

Khwaja J. Zakriya; Colleen Christmas; James F. Wenz; Shawn Franckowiak; Ross Anderson; Frederick E. Sieber

2002-01-01

341

Topical use of antifibrinolytic agents reduces postoperative bleeding: a double-blind, prospective, randomized study  

Microsoft Academic Search

Objective: Postoperative bleeding is still one of the most common complications of cardiac surgery. Antifibrinolytic agents successfully reduce bleeding, but there are controversies concerning adverse effects after their systemic use. By topical application of antifibrinolytic agents in pericardial cavity, most of these effects are avoided. We compared the effects of topically applied aprotinin, tranexamic acid and placebo on postoperative bleeding

Davor Baric; Bojan Biocina; Daniel Unic; Zeljko Sutlic; Igor Rudez; Vesna Bacic Vrca; Kristina Brkic; Mira Ivkovic

2007-01-01

342

Topical use of antifibrinolytic agents reduces postoperative bleeding: a double-blind, prospective, randomized study  

Microsoft Academic Search

Objective: Postoperative bleeding is still one of the most common complications of cardiac surgery. Antifibrinolytic agents successfully reduce bleeding, but there are controversies concerning adverse effects after their systemic use. By topical application of antifibrinolytic agents in pericardial cavity, most of these effects are avoided. We compared the effects of topically applied aprotinin, tranexamic acid and placebo on postoperative bleeding

Davor Bari; Bojan Biocina; Daniel Uni; Zeljko Sutlic; Igor Rude; Vesna Bacic Vrca; Kristina Brkic; Mira Ivkovic

343

Use of Three Evidence-Based Postoperative Pain Assessment Practices by Registered Nurses  

Microsoft Academic Search

To provide optimal postoperative pain relief, nursing practice should be based on the best evidence available. For over 20 years, results of studies regarding nurses' use of evidence-based practices, including postoperative pain assessment practices, have shown that nurses use the practices inconsistently. The present cross-sectional survey study was conducted to: 1) determine the extent to which registered nurses caring for

Cathy L. Carlson

2009-01-01

344

The Effect of Analgesic Technique on Postoperative Patient-Reported Outcomes Including Analgesia: A Systematic Review  

Microsoft Academic Search

BACKGROUND: The effect of postoperative analgesia on patient-reported outcomes, such as quality of life, quality of recovery, and patient satisfaction, has not been systematically examined. These outcomes are assessed from the patient's perspec- tive and are recognized as valid and important end-points in clinical medicine and research. We performed a systematic review to examine the effect of postoperative analgesia on

Spencer S. Liu; Christopher L. Wu

2007-01-01

345

Intraoperative cerebral high intensity transient signals and postoperative cognitive function: a systematic review  

PubMed Central

Summary Microemboli during surgery have been hypothesized to cause postoperative cognitive changes. The purpose of this article was to systematically review the available literature related to intraoperative microemboli, measured with transcranial Doppler ultrasound and postoperative cognitive function. The literature remains largely undecided on the role of microemboli and cognitive impairment after surgery, because most studies underpowered to show a relationship. PMID:18723157

Martin, Kristin K; Wigginton, Jeremy B.; Babikian, Viken L; Pochay, Val E.; Crittenden, Michael D.; Rudolph, James L.

2009-01-01

346

Scanning electron-microscopic lesions in Crohn's disease: Relevance for the interpretation of postoperative recurrence  

Microsoft Academic Search

Background\\/Aims: Endoscopic postoperative recurrence often occurs a few months after surgical therapy for Crohn's disease, even if the resection margins were macroscopically free of disease. Why the disease primarily recurs at the anastomotic site is not known. This study investigated resection margins in Crohn's disease in an attempt to clarify whether early lesions are relevant to the interpretation of postoperative

Eckhard Nagel; Michael Bartels; Rudolf Pichlmayr

1995-01-01

347

The incidence of postoperative ileus in patients who underwent robotic assisted radical prostatectomy  

PubMed Central

Introduction Our aim was to examine the incidence and risk factors of postoperative ileus among patients who underwent robot–assisted radical prostatectomy (RARP). Material and methods We retrospectively reviewed 239 patients who underwent RARP transperitoneally between February 2009 and December 2011. Patients switched to open surgery were excluded. We defined postoperative ileus as intolerance of a solid diet continued until the third postoperative day and beyond. By Clavien classification, we evaluated the perioperative complications that cause or contribute to postoperative ileus. Similarly, we analyzed the impact of anesthesia risk score on the incidence of postoperative ileus. Results The study included 228 patients. The mean period to tolerate solid food was 1.24 days. Only 6 patients experienced postoperative ileus, all of whom were treated with a conservative approach. The two groups differed significantly in the duration of abdominal drainage, hospital stay, modified Clavien classification, and the presence of comorbidity diabetes mellitus (P <0.5 for all factors). Multiple logistic regression analysis revealed that diabetes mellitus was an independent risk factor for postoperative ileus. Conclusions We suggest that diabetes mellitus is an independent risk factor for postoperative ileus in patients undergoing robot–assisted radical prostatectomy. PMID:24982775

Ozdemir, Ahmet Tunc; Altinova, Serkan; Serefoglu, Ege Can; Cimen, Ibrahim Haci; Balbay, Derya Mevlana

2014-01-01

348

Postoperative perforation of the Schneiderian membrane in maxillary sinus augmentation: a case report.  

PubMed

Perforation of the Schneiderian membrane constitutes a major intraoperative complication of maxillary sinus floor elevation with graft materials, but postoperative perforation of the sinus membrane is very rare. This case report demonstrates that conservative treatment involving drainage and the administration of systemic antibiotics can be used to successfully treat postoperative sinus membrane perforation with infection of the graft material. PMID:25020219

Jo, Kyu-Hong; Yoon, Kyu-Ho; Cheong, Jeong-Kwon; Jeon, In-Seong

2014-07-01

349

The Importance of Pre and Postoperative Physical Activity Counseling in Bariatric Surgery  

PubMed Central

There is increasing evidence that physical activity (PA) can enhance weight loss and other outcomes after bariatric surgery. However, most preoperative patients are insufficiently active, and without support, fail to make substantial increases in their PA postoperatively. This review provides the rationale for PA counseling in bariatric surgery and describes how to appropriately tailor strategies to pre- and postoperative patients. PMID:22710705

King, Wendy C; Bond, Dale S

2012-01-01

350

The clinical value of faecal calprotectin and lactoferrin measurement in postoperative Crohn's disease.  

PubMed

Most patients with Crohn's disease (CD) ultimately require one or more operations over their lifetime. Nevertheless, surgery is not a cure and postoperative CD recurrence is common. Ileocolonoscopy has been considered to be the gold standard in the diagnosis and monitoring of postoperative recurrence in patients with CD. However, endoscopy is a time-consuming and invasive procedure. Simple and non-invasive methods for the detection of postoperative recurrence are desirable. Faecal inflammatory biomarkers such as calprotectin and lactoferrin provide an accurate and non-invasive diagnostic and monitoring modality for inflammatory bowel disease. However, there have been limited data on the role of faecal biomarkers in the postoperative setting. Recently, several studies evaluated the value of faecal calprotectin and lactoferrin measurement after surgery for CD. This review was conducted to assess the role of faecal calprotectin and lactoferrin measurements in patients with postoperative CD. PMID:25653853

Yamamoto, Takayuki

2015-02-01

351

The clinical value of faecal calprotectin and lactoferrin measurement in postoperative Crohn’s disease  

PubMed Central

Most patients with Crohn’s disease (CD) ultimately require one or more operations over their lifetime. Nevertheless, surgery is not a cure and postoperative CD recurrence is common. Ileocolonoscopy has been considered to be the gold standard in the diagnosis and monitoring of postoperative recurrence in patients with CD. However, endoscopy is a time-consuming and invasive procedure. Simple and non-invasive methods for the detection of postoperative recurrence are desirable. Faecal inflammatory biomarkers such as calprotectin and lactoferrin provide an accurate and non-invasive diagnostic and monitoring modality for inflammatory bowel disease. However, there have been limited data on the role of faecal biomarkers in the postoperative setting. Recently, several studies evaluated the value of faecal calprotectin and lactoferrin measurement after surgery for CD. This review was conducted to assess the role of faecal calprotectin and lactoferrin measurements in patients with postoperative CD. PMID:25653853

2015-01-01

352

Assessment of pain during rest and during activities in the postoperative period of cardiac surgery  

PubMed Central

Objective to assess the intensity and site of pain after Cardiac Surgery through sternotomy during rest and while performing five activities. Method descriptive study with a prospective cohort design. A total of 48 individuals participated in the study. A Multidimensional Scale for Pain Assessment was used. Results postoperative pain from cardiac surgery was moderate during rest and decreased over time. Pain was also moderate during activities performed on the 1st and 2nd postoperative days and decreased from the 3rd postoperative day, with the exception of coughing, which diminished only on the 6th postoperative day. Coughing, turning over, deep breathing and rest are presented in decreased order of intensity. The region of the sternum was the most frequently reported site of pain. Conclusion the assessment of pain in the individuals who underwent cardiac surgery during rest and during activities is extremely important to adapt management and avoid postoperative complications and delayed surgical recovery. PMID:24553714

de Mello, Larissa Coelho; Rosatti, Silvio Fernando Castro; Hortense, Priscilla

2014-01-01

353

Adenoid cystic carcinoma of the tracheobronchial system: the role of postoperative radiotherapy.  

PubMed

To clarify the role of postoperative radiotherapy for adenoid cystic carcinoma of the tracheobronchial system (ACC), we analyzed patients treated at the National Cancer Center Hospital, Tokyo. Seven patients with ACC were treated with resective surgery and postoperative radiotherapy from 1962-1990. None of the primary lesions was completely surgically resected. Postoperative irradiation was delivered by standard fractionation at a dose range of 49.2-72 Gy. Four of seven patients lived more than 5 years, up to 21 years, without local recurrence. In contrast, three other patients who showed recurrence within 2 years died of disease before 5 years. Three of four patients who received postoperative irradiation of 60 Gy or more attained local control. One of three patients who received less than 60 Gy failed locally. A high dose of postoperative radiotherapy for patients with a positive surgical margin of ACC seems to improve local control and result in long-term survival. PMID:7597201

Ogino, T; Ono, R; Shimizu, W; Ikeda, H

1995-01-01

354

Unternehmensweiter Ansatz einer Governance, Risk und Compliance-Lösung  

Microsoft Academic Search

\\u000a Für viele Unternehmen besteht die Herausforderung, ihre Risiken effektiver zu managen, da Compliance Standards kontinuierlich\\u000a weiterentwickelt werden und die Komplexität von Unternehmen ständig steigt. Diese Situation wird zunehmend verschärft durch\\u000a die Konzentration von Verantwortung auf wenige Entscheidungsträger und ein überwiegend reaktives Handeln anstelle eines proaktiven\\u000a Agierens im Bereich Risk und Compliance Management. Weiterhin existieren nicht immer adäquate Compliance-Prozesse und Steuerungsmechanismen.

Frank Standke

355

Patterns of Failure after Postoperative Radiation Therapy for Endometrial Carcinoma  

PubMed Central

Purpose We tried to investigate the outcome and patterns of failure of endometrial cancer patients who were treated with surgery and postoperative radiation therapy (RT). Materials and Methods Eighty-three patients with endometrial cancer who received postoperative RT between May 1979 and August 2000 were included in this retrospective study. Forty-one patients received total abdominal hysterectomy, 41 patients received Wertheim's operation and 1 underwent vaginal hysterectomy. Pelvic lymph node dissection or pelvic lymph node sampling was done in 56 patients and peritoneal cytology was done in 35. All the patients were staged according to 1988 FIGO (International Federation of Gynecology and Obstetrics) staging system; 2 were stage IA, 23 were stage IB, 20 were stage IC, 4 were stage IIA, 5 were stage IIB, 9 were stage IIIA, 2 were stage IIIB and 18 were stage IIIC. The histologic diagnoses were adenocarcinoma in seventy-four patients (89%). The histologic grades were Grade 1, 2 and 3 in 21 (25%), 43 (52%) and 10 (12%) patients, respectively. All the patients received external beam RT (EBRT) with a median dose of 5,040 cGy (range: 4,500~5,075 cGy) to the whole pelvis. Five patients with pathologically confirmed paraaortic lymph node metastasis received 4500 cGy to the paraaortic lymph nodes. Fifteen patients received low-dose intracavitary brachytherapy after their EBRT. A total dose of 7,500~9,540 cGy (median dose: 8511) was prescribed to the vaginal surface. Results Overall, 11 patients (13%) experienced disease relapse: 4 with initial stage I or II disease and 7 with initial stage III disease. Among the 54 stage I or II patients, 1 (2%) relapsed in the pelvis only, 2 (4%) relapsed in the vagina and distant organs, and 1 (2%) relapsed in the paraaortic lymph nodes (PANs). Among the 29 stage III patients, 1 (3%) relapsed in the vagina. The most common sites of failure for the stage III patients were the peritoneum (3 patients, 10%), PANs (2 patients, 7%), and lung (2 patients, 7%). With a median follow-up period of 86 months, the overall survival (OS) and disease-free survival (DFS) rates at 5 years were 87% for both. The five-year DFS rate was 93%, 100% and 74% for the stage I, II and III patients, respectively. Three patients experienced severe radiation-related late complications: RTOG (Radiation Therapy Oncology Group) grade 3 radiation cystitis was seen in one patient, and grade 3 bowel obstruction was seen in two patients. Conclusions Postoperative RT was useful for controlling pelvic disease. The major patterns of failure for stage III patients were peritoneal seeding and distant metastasis. Selective use of whole abdominal radiotherapy or adjuvant chemotherapy may improve the therapeutic outcome of these patients. PMID:19771273

Kim, Suzy; Lee, Hyo-Pyo; Kang, Soon-Beom; Song, Yong-Sang; Park, Noh-Hyun; Ha, Sung Whan

2006-01-01

356

Sudan und Sd-Sudan. Vom Konflikt zur Kooperation?  

E-print Network

Sudan und Süd-Sudan. Vom Konflikt zur Kooperation? Professor Dr. Karl Wohlmuth (Fachbereich aktuellen Konflikte zwischen dem Sudan und dem Süd-Sudan haben, wie die Konflikte innerhalb der beiden internationalen Grenze zwischen Sudan und Süd-Sudan mobilisiert werden können. Schon vor der Unabhängigkeit des

Koenig, Friederike - Fachbereich 2 Biologie

357

Atom-und Quantenphysik Innsbruck, WS 2014/15  

E-print Network

Physik III Atom- und Quantenphysik Innsbruck, WS 2014/15 Literatur: (eine Auswahl zur Einführung) W. Demtröder Experimentalphysik 3, Atome, Moleküle und Festkörper, 4. Auflage Springer Lehrbuch, Berlin 2010 H. Haken, H. C. Wolf Atom- und Quantenphysik 8. Auflage, Springer, Berlin 2003 R. Eisberg, R. Resnick

Blatt, Rainer

358

Atom-und Quantenphysik Innsbruck, WS 2012/13  

E-print Network

Physik III Atom- und Quantenphysik Innsbruck, WS 2012/13 Literatur: (eine Auswahl zur Einführung) W. Demtröder Experimentalphysik 3, Atome, Moleküle und Festkörper, 4. Auflage Springer Lehrbuch, Berlin 2010 H. Haken, H. C. Wolf Atom- und Quantenphysik 8. Auflage, Springer, Berlin 2003 R. Eisberg, R. Resnick

Blatt, Rainer

359

Das polyzystische Ovarialsyndrom: Im Spannungsfeld von Hormonen und Stoffwechsel  

Microsoft Academic Search

schen Messungen und Hirsutismus-Score. Ein Hormonstatus mit Bestimmung von Androgenen ist unerlässlich, ein LHRH-Test kann weitere diagnos- tische Hinweise liefern. Weiters sollten zur meta- bolischen Abklärung ein oraler Glukosetoleranz- test, eine Messung der Körperfettverteilung und die Bestimmung eines Lipidstatus erfolgen. Thera- peutisch ist vor allem bei adipösen Frauen eine Lebensstilintervention am wichtigsten, zusätzlich kommen Insulinsensitizer und orale Kontrazeptiva zum Einsatz.

E. Wehr; B. Obermayer-Pietsch

2010-01-01

360

www.nursing.und.edu Issue 3 Volume I  

E-print Network

www.nursing.und.edu Issue 3 Volume I Winter 2011 CONNECTIONSUND College of Nursing Alumni Magazine L e a v i n g A Legacy Inspirational Students 6 #12;www.nursing.und.edu1 CONNECTIONS'11UND College of Nursing Alumni Magazine Dr. Robert O. Kelley, President, University of North Dakota Dr. Julie Anderson

Delene, David J.

361

Klinik fr Psychosomatik und Psychotherapie PD Dr. Peter Angerer  

E-print Network

Klinik für Psychosomatik und Psychotherapie 6.11.2008 PD Dr. Peter Angerer Dr. Mechthild Heinmüller. Harald Gündel Medizinische Hochschule Hannover Klinik für Psychosomatik und Psychotherapie Dr. Heribert, Psychotherapie und Medizinische Psychologie Betriebliche Gesundheitsförderung am Beispiel der Studie: Prävention

Manstein, Dietmar J.

362

Institut fr Evangelische Theologie und Religionspdagogik ,,Geistes-Geschichten"  

E-print Network

.00 Uhr: Prof. Dr. Johannes Fried (Johann-Wolfgang-Goethe-Universität Frankfurt/Main) Neurokulturelle Carl von Ossietzky Universität Oldenburg BIS-Vortragssaal (Bibliotheksgebäude, Uhlhornsweg) Mittwoch) Erinnern und Vergessen: Neurobiologie und Psychologie von Lernen und Gedächtnis Donnerstag, 16. 10. 2008 9

Damm, Werner

363

Anwendungen und Technologien des Web 2.0: Ein berblick  

E-print Network

Anwendungen und Technologien des Web 2.0: Ein �berblick Alexander Stocker1 und Klaus Tochtermann1 2 formieren. Folglich definiert sich die soziale Komponente des Web 2.0 über ein verändertes Verhalten seiner User. Web-2.0-Plattformen sind jedoch vielmehr sozio-technische Artefakte und basie- ren auf speziellen

Hammerton, James

364

Analysis of risk factors for postoperative pancreatic fistula following pancreaticoduodenectomy  

PubMed Central

AIM: To explore the morbidity and risk factors of postoperative pancreatic fistula (POPF) following pancreaticoduodenectomy. METHODS: The data from 196 consecutive patients who underwent pancreaticoduodenectomy, performed by different surgeons, in the General Hospital of the People’s Liberation Army between January 1st, 2013 and December 31st, 2013 were retrospectively collected for analysis. The diagnoses of POPF and clinically relevant (CR)-POPF following pancreaticoduodenectomy were judged strictly by the International Study Group on Pancreatic Fistula Definition. Univariate analysis was performed to analyze the following factors: patient age, sex, body mass index (BMI), hypertension, diabetes mellitus, serum CA19-9 level, history of jaundice, serum albumin level, blood loss volume, pancreatic duct diameter, pylorus preserving pancreaticoduodenectomy, pancreatic drainage and pancreaticojejunostomy. Multivariate logistic regression analysis was used to determine the main independent risk factors for POPF. RESULTS: POPF occurred in 126 (64.3%) of the patients, and the incidence of CR-POPF was 32.7% (64/196). Patient characteristics of age, sex, BMI, hypertension, diabetes mellitus, serum CA19-9 level, history of jaundice, serum albumin level, blood loss volume, pylorus preserving pancreaticoduodenectomy and pancreaticojejunostomy showed no statistical difference related to the morbidity of POPF or CR-POPF. Pancreatic duct diameter was found to be significantly correlated with POPF rates by univariate analysis and multivariate regression analysis, with a pancreatic duct diameter ? 3 mm being an independent risk factor for POPF (OR = 0.291; P = 0.000) and CR-POPF (OR = 0.399; P = 0.004). The CR-POPF rate was higher in patients without external pancreatic stenting, which was found to be an independent risk factor for CR-POPF (OR = 0.394; P = 0.012). Among the entire patient series, there were three postoperative deaths, giving a total mortality rate of 1.5% (3/196), and the mortality associated with pancreatic fistula was 2.4% (3/126). CONCLUSION: A pancreatic duct diameter ? 3 mm is an independent risk factor for POPF. External stent drainage of pancreatic secretion may reduce CR-POPF mortality and POPF severity. PMID:25516663

Liu, Qi-Yu; Zhang, Wen-Zhi; Xia, Hong-Tian; Leng, Jian-Jun; Wan, Tao; Liang, Bin; Yang, Tao; Dong, Jia-Hong

2014-01-01

365

The influence of postoperative epidural analgesia on postoperative pain and stress response after major spine surgery--a randomized controlled double blind study.  

PubMed

Major spinal surgery is associated with severe postoperative pain and stress response, bowel dysfunction, and a potential for chronic pain development. Epidural analgesia has been shown to be advantageous compared to intravenous analgesia alone. The aim of the study was to investigate whether postoperative addition of epidural levobupivacaine to intravenous opioid analgesia offers advantage over intravenous opioid analgesia alone. Eighty-one patients scheduled for spinal fusion were enrolled in the study and randomized into two groups. Postoperatively, group A received 0.125% epidural levobupivacaine and group B received saline. Both groups also received intravenous piritramide as a rescue analgesic. Pain intensity, rescue analgesic consumption, blood glucose, cholesterol and cortisol levels, postoperative blood loss, paresthesia, time to first postoperative defecation, and length of hospital stay were recorded. Sixty-eight patients completed the study. The visual analog scale score (mean 2 vs. 4, p = 0.01), consumption ofpiritramide (25 mg vs. 51.5 mg, p = 0.01) and metamizole (1400 vs. 1875 mg, p < 0.01), incidence of nausea (6% vs. 28% p = 0.02) and blood loss (450 mL vs. 650 mL, p < 0.05) were significantly lower in group A. Bowel recovery and first postoperative defecation also occurred earlier in group A (6% vs. 45%, p < 0.01). Blood cortisol, glucose and cholesterol levels and the incidence of paresthesia did not differ between the groups. In conclusion, after spinal fusion, postoperative epidural administration of levobupivacaine provides better analgesia and fewer side effects with no impact on stress response. PMID:25163233

Servicl-Kuchler, Darja; Maldini, Branka; Borgeat, Alain; Bili?, Nada; Kosak, Robert; Mavcic, Blaz; Novak-Jankovic, Vesna

2014-06-01

366

Das Ising-Modell und Monte-Carlo-Simulation Das Ising-Modell und Monte-Carlo-Simulation  

E-print Network

Das Ising-Modell und Monte-Carlo-Simulation Das Ising-Modell und Monte-Carlo-Simulation Aljoscha Rheinwalt 14. Januar 2009 Betreuender Professor: Prof. M. M¨uller-Preu�ker #12;Das Ising-Modell und Monte-Carlo-Simulation Gliederung Gliederung Ising-Modell Definition Anwendungen Numerische Analyse Statistische Beschreibung Monte-Carlo

367

zentrum fr Psychosoziale medizin ABTEIlUNG KINDER-UND JUGENDPSyCHIATRIE UND PSyCHOTHERAPIE  

E-print Network

zentrum für Psychosoziale medizin ABTEIlUNG KINDER- UND JUGENDPSyCHIATRIE UND PSyCHOTHERAPIE centre for Psychosocial medicine DEPARTMENT OF CHIlD AND ADOlESCENT PSyCHIATRy AND PSyCHOTHERAPy AbteilungsdirektorGendpsycHiAtrie und psycHotHerApie Centre for Psychosocial Medicine depArtment of cHild And Adolescent psyc

Gollisch, Tim

368

Überlegungen zum Denken des Körpers als Effekt. Leib-Seele-Problem und Kausalität bei Wilhelm Wundt und Sigmund Freud  

Microsoft Academic Search

Mein Vortrag versucht, einige philosophisch-begriffsgeschichtliche Grundlagen des modernen Körperverständnisses zu klären. Mit der cartesischen Neudefinition von Leib und Seele als zwei vollkommen getrennten Substanzen geht eine strenge Aufteilung der Wissenschaften bezüglich ihres Untersuchungsgegenstandes und ihrer Methodik einher: Naturwissenschaft untersucht Körperliches aufgrund des Prinzips der mechanisch gedachten Kausalität, Seele oder Geist hingegen sind nicht kausal zu denken, und fallen in den

Catherine Newmark

2003-01-01

369

Postoperative surgical site infection following acetabular fracture fixation.  

PubMed

Postoperative surgical site infection (SSI) in orthopaedic trauma surgery is uncommon, but can present serious complications. This study was designed to assess the prevalence of, and to identify the risk factors for, SSI following acetabular fracture open reduction and internal fixation. A total of 326 consecutive patients who underwent acetabular fracture surgery were retrospectively reviewed. There were 17 patients (5.2%) who developed a SSI, including 10 deep infections and 7 superficial infections. Staphylococcus aureus was the most common causative pathogens in 9 patients, and was Methicillin-resistant in 3 patients. Enterococcus faecalis was found in 6 patients, Staphylococcus epidermidis in 3 patients, and Pseudomonas aeruginosa and enterbacter cloacae in 2 patients each. Fourteen of 17 patients developed their infection within 4 weeks after the fixation. Univariate analysis demonstrated that the SSI group had statistically significant higher Injury Severity Score, longer intensive care unit (ICU) stays, larger amount of packed red blood cells transfused, longer operative time, larger estimated operative blood loss, higher body mass index (BMI), more frequent performance of combined approach, embolisation of internal iliac arteries, association of urinary tract injury, and Morel-Lavallée lesion compared to the no SSI group. Multivariate analysis using these 10 parameters showed that BMI, ICU stay, and Morel-Lavallée lesion were independently significant risk factors for SSI. To reduce the incidence of SSI following acetabular fracture surgery, special attention should be directed at the care of obese patients, patients requiring ICU care, and patients with associated Morel-Lavallée lesions. PMID:20004894

Suzuki, Takashi; Morgan, Steven J; Smith, Wade R; Stahel, Philip F; Gillani, Syed A; Hak, David J

2010-04-01

370

“Acute postoperative open abdominal wall”: Nosological concept and treatment implications  

PubMed Central

The so-called “burst abdomen” has been described for many years and is a well-known clinical condition, whereas the concept of the “open abdomen” is relatively new. In clinical practice, both nosological entities are characterized by a complex spectrum of symptoms apparently disconnected, which in many cases poses a great challenge for surgical repair. In order to assess the management of these disorders in a more comprehensive and integral fashion, the concept of “acute postoperative open abdominal wall” (acute POAW) is presented, which in turn can be divided into “intentional” or planned acute POAW and “unintentional” or unplanned POAW. The understanding of the acute POAW as a single clinical process not only allows a better optimization of the therapeutic approach in the surgical repair of abdominal wall-related disorders, but also the stratification and collection of data in different patient subsets, favoring a better knowledge of the wide spectrum of conditions involved in the surgical reconstruction of the abdominal wall. PMID:24392182

López-Cano, Manuel; Pereira, José A; Armengol-Carrasco, Manuel

2013-01-01

371

Percutaneous Management of Postoperative Duodenal Stump Leakage with Foley Catheter  

SciTech Connect

Purpose: This study was designed to evaluate retrospectively the safety and efficacy of the percutaneous management of duodenal stump leakage with a Foley catheter after subtotal gastrectomy. Methods: Ten consecutive patients (M:F = 9:1, median age: 64 years) were included in this retrospective study. The duodenal stump leakages were diagnosed in all the patients within a median of 10 days (range, 6-20). At first, the patients underwent percutaneous drainage on the day of or the day after confirmation of the presence of duodenal stump leakage, and then the Foley catheters were replaced at a median of 9 days (range, 6-38) after the percutaneous drainage. Results: Foley catheters were placed successfully in the duodenal lumen of all the patients under a fluoroscopic guide. No complication was observed during and after the procedures in all the patients. All of the patients started a regular diet 1 day after the Foley catheter placement. The patients were discharged at a median of 7 days (range, 5-14) after the Foley catheter placement. The catheters were removed in an outpatient clinic 10-58 days (median, 28) after the Foley catheter placement. Conclusions: Fluoroscopy-guided percutaneous Foley catheter placement may be a safe and effective treatment option for postoperative duodenal stump leakage and may allow for shorter hospital stays, earlier oral intake, and more effective control of leakage sites.

Oh, Jung Suk, E-mail: oj-cumc@daum.net; Lee, Hae Giu, E-mail: hgleehfh@catholic.ac.kr; Chun, Ho Jong; Choi, Byung Gil [Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Department of Radiology (Korea, Republic of)] [Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Department of Radiology (Korea, Republic of); Lee, Sang Hoon; Hahn, Seong Tai [Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Department of Radiology (Korea, Republic of)] [Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Department of Radiology (Korea, Republic of); Ohm, Joon Young [Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Department of Radiology (Korea, Republic of)] [Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Department of Radiology (Korea, Republic of)

2013-10-15

372

Update on the management of postoperative nausea and vomiting.  

PubMed

New antiemetic drug developments, formulations, guidelines, risk evaluation, and controversies have occurred in the area of postoperative nausea and vomiting (PONV). These developments have helped improve our understanding of the prevention and treatment of PONV in the postanesthesia care unit and after discharge home or to the hospital ward. Antiemetic drug research has resulted in the introduction of the second-generation 5-hydroxytryptamine-3 (5-HT3) receptor antagonist palonosetron and the neurokinin-1 (NK-1) receptor antagonist aprepitant, as well as new data on existing antiemetics. The next frontier and need for further nausea and vomiting research and therapy is the area of postdischarge nausea and vomiting after the patient is discharged home from phase II of the ambulatory stepdown unit or to the hospital ward. Antiemetic drug selection depends on efficacy, cost, safety, and ease of dosing. Safety concerns have arisen regarding the side effects of antiemetics, specifically their effect on the ECG with prolongation of the QTc interval by the butyrophenones and the first-generation 5-HT3 receptor antagonist class of antiemetics. The impact of pharmocogenetics on antiemetic drug metabolism and their resulting efficacy has been correlated with genetic makeup affecting drug response. A discussion of ethics in PONV research has been initiated by the meta-analysis of PONV studies. To help guide antiemetic selection and PONV therapy for clinical practitioners, the Society of Ambulatory Anesthesia (SAMBA) PONV consensus guidelines have been introduced and updated. PMID:24057415

Kovac, Anthony L

2013-09-01

373

Pathophysiological and neurochemical mechanisms of postoperative nausea and vomiting  

PubMed Central

Clinical research shows that postoperative nausea and vomiting (PONV) is caused primarily by the use of inhalational anesthesia and opioid analgesics. PONV is also increased by several risk predictors, including a young age, female sex, lack of smoking, and a history of motion sickness. Genetic studies are beginning to shed light on the variability in patient experiences of PONV by assessing polymorphisms of gene targets known to play roles in emesis (serotonin type 3, 5-HT3; opioid; muscarinic; and dopamine type 2, D2, receptors) and the metabolism of antiemetic drugs (e.g., ondansetron). Significant numbers of clinical trials have produced valuable information on pharmacological targets important for controlling PONV (e.g., 5-HT3 and D2), leading to the current multi-modal approach to inhibit multiple sites in this complex neural system. Despite these significant advances, there is still a lack of fundamental knowledge of the mechanisms that drive the hindbrain central pattern generator (emesis) and forebrain pathways (nausea) that produce PONV, particularly the responses to inhalational anesthesia. This gap in knowledge has limited the development of novel effective therapies of PONV. The current review presents the state of knowledge on the biological mechanisms responsible for PONV, summarizing both preclinical and clinical evidence. Finally, potential ways to advance the research of PONV and more recent developments on the study of postdischarge nausea and vomiting (PDNV) are discussed. PMID:24495419

Horn, Charles C.; Wallisch, William J.; Homanics, Gregg E.; Williams, John P.

2013-01-01

374

The sensitivity of radiography of the postoperative stomach  

SciTech Connect

The results of radiology and endoscopy were compared in 140 patients who had undergone gastric surgery for ulcer disease. Of 74 patients who were examined with single-contrast radiography, 37 had abnormalities that were demonstrated endoscopically. The radiographic sensitivities in these patients were: gastritis 2/22 (9%); ulcer 3/5 (60%); obstruction 8/8 (100%); and miscellaneous abnormalities 2/2 (100%). The predictive accuracy of a diagnois of ulcer was 38%. Of the 66 patients who were examined with double-contrast radiography, 33 abnormalities were found with endoscopy. The radiographic sensitivities were: gastritis 3/13 (23%); ulcer 7/10 (70%); obstruction 4/4 (100%); and miscellaneous abnormalities 6/6 (100%). The predictive accuracy of a diagnosis of ulcer was 44%. Radiology appears to be unreliable in diagnosing gastritis and recurrent ulceration in the post-operation stomach. The double-contrast technique does not offer significant improvement over the single-contrast method in evaluating these postoperative problems.

Ott, D.J.; Munitz, H.A.; Gelfand, D.W.; Lane, T.G.; Wu, W.C.

1982-09-01

375

Dexmedetomidine improves early postoperative cognitive dysfunction in aged mice.  

PubMed

Postoperative cognitive dysfunction (POCD) is a frequent complication following major surgery in the elderly. However, the exact pathogenic mechanisms are still unknown. Dexmedetomidine, a selective alpha 2 adrenal receptor agonist, was revealed anesthesia and brain protective role. The present study aimed to examine whether dexmedetomdine protects against POCD induced by major surgical trauma under general anesthesia in aged mice. In the present study, cognitive function was assessed by Y-maze. Proinflammatory cytokines interleukin-1? (IL-1?) and tumor necrosis factor (TNF-?), apoptosis-related factor caspase-3 and Bax were detected by real-time PCR, Western blot or immunohistochemistry. The results showed that anesthesia alone caused weak cognitive dysfunction on the first day after general anesthesia. Cognitive function in mice with splenectomy under general anesthesia was significantly exacerbated at the first and third days after surgery, and was significantly improved by dexmedetomidine administration. Splenectomy increased the expression of IL-1?, TNF-?, Bax and caspase-3 in hippocampus. These changes were significantly inversed by dexmedetomidine. These results suggest that hippocampal inflammatory response and neuronal apoptosis may contribute to POCD, and selective alpha 2 adrenal receptor excitation play a protective role. PMID:25460022

Qian, Xiao-Lan; Zhang, Wei; Liu, Ming-Zheng; Zhou, Yu-Bing; Zhang, Jing-Min; Han, Li; Peng, You-Mei; Jiang, Jin-Hua; Wang, Qing-Duan

2015-01-01

376

The Effects of Prucalopride on Postoperative Ileus in Guinea Pigs  

PubMed Central

Purpose Postoperative ileus (POI) is an impairment of coordinated gastrointestinal (GI) motility that develops as a consequence of abdominal surgery and is a major factor contributing to patient morbidity and prolonged hospitalization. The aim of this study was to investigate the effects of different 5-hydroxytryptamine 4 (5-HT4) receptor agonists, which stimulate excitatory pathways, on a POI model. Materials and Methods The experimental model of POI in guinea pigs was created by laparotomy, gentle manipulation of the cecum for 60 seconds, and closure by suture, all under anesthesia. Different degrees of restoration of GI transit were measured by the migration of charcoal. Colonic transit was indirectly assessed via measurement of fecal pellet output every hour for 5 hours after administration of various doses of mosapride, tegaserod, prucalopride, and 5-HT. Results Charcoal transit assay showed that various 5-HT4 receptor agonists can accelerate delayed upper GI transit in a dose-dependent manner. However, fecal pellet output assay suggested that only prucalopride had a significant effect in accelerating colonic motility in POI. Conclusion Although mosapride, tegaserod, and prucalopride produce beneficial effects to hasten upper GI transit in the POI model, prucalopride administered orally restores lower GI transit as well as upper GI transit after operation in a conscious guinea pig. This drug may serve as a useful candidate for examination in a clinical trial for POI. PMID:23709417

Park, Soo Jung; Choi, Eun Ju; Yoon, Young Hoon

2013-01-01

377

Development of a Prediction Rule for Estimating Postoperative Pulmonary Complications  

PubMed Central

Patient- and procedure-related factors associated with postoperative pulmonary complications (PPCs) have changed over the last decade. Therefore, we sought to identify independent risk factors of PPCs and to develop a clinically applicable scoring system. We retrospectively analyzed clinical data from 2,059 patients who received preoperative evaluations from respiratory physicians between June 2011 and October 2012. A new scoring system for estimating PPCs was developed using beta coefficients of the final multiple regression models. Of the 2,059 patients studied, 140 (6.8%) had PPCs. A multiple logistic regression model revealed seven independent risk factors (with scores in parentheses): age ?70 years (2 points), current smoker (1 point), the presence of airflow limitation (1 point), American Society of Anesthesiologists class ?2 (1 point), serum albumin <4 g/dL (1 point), emergency surgery (2 points), and non-laparoscopic abdominal/cardiac/aortic aneurysm repair surgery (4 points). The area under the curve was 0.79 (95% CI, 0.75–0.83) with the newly developed model. The new risk stratification including laparoscopic surgery has a good discriminative ability for estimating PPCs in our study cohort. Further research is needed to validate this new prediction rule. PMID:25437175

Eom, Jung Seop; Yoo, Hongseok; Song, Wonjun; Han, Sangbin; Lee, Kyung Jong; Jeon, Kyeongman; Um, Sang-Won; Koh, Won-Jung; Suh, Gee Young; Chung, Man Pyo; Kim, Hojoong; Kwon, O. Jung; Woo, Sookyoung; Park, Hye Yun

2014-01-01

378

[Pathogenetic correction of postoperative inflammation in modern rhinosurgery].  

PubMed

This study included 20 patients presenting with polypous rhinosinusitis examined before and after endoscopic intervention in the nasal cavity and paranasal sinuses. Nitric oxide (NO) content in nasal secretion and polypoid tissue was estimated from the concentration of nitrates that, together with nitrites, are the final products of oxidation of nitric oxide and serve as markers of endogenous NO. Nitrates in the nasal secretion, endonasal mucosa, and polypous tissue were determined by the ionometric technique. Their content was additionally measured in 12 subjects without polypous rhinosinusitis. The nasal secretion and polypous tissue of PRS patients were found to contain nitrates at a higher concentration compared with healthy subjects. Nitrate concentrations in the nasal secretion and polypous tissue of PRS patients were not significantly different. Mean saccharine transport time in the nasal cavity of the patients with an elevated level of nitrates in the nasal secretion was significantly higher than in PRS patients with the lowered nitrate levels. It means that high concentrations of nitric oxide markers in the nasal secretion and polypous tissue of the patients with polypous rhinosinusitis have negative effect on the efficiency of mucociliary transport. In addition, results of the study confirm the possibility of anti-inflammatory therapy with Erespal (fenspirid) for the correction of inflammatory changes during the postoperative period. PMID:21105352

Kim, I A; Nosulia, E V

2010-01-01

379

Infants undergoing pyloromyotomy are not at risk for postoperative apnea. Staff of Sutter Community Hospitals Sleep Disorders Center.  

PubMed

Thirty term infants undergoing general anesthesia and pyloromyotomy had pre- and postoperative sleep studies to determine whether these infants were at risk for postoperative apnea. Sleep studies showed an improved respiratory disturbance index (RDI) after surgery. Postoperatively, apnea indices were lower and lowest oxygen saturation values were increased compared to the infants' preoperative status. We conclude that pyloromyotomy does not elicit postoperative apnea in term infants. PMID:10230928

Chipps, B E; Moynihan, R; Schieble, T; Stene, R; Feaster, W; Marr, C; Greenholz, S; Poulos, N; Groza, D

1999-04-01

380

Wie LCC-Management die Produktionstechnik und die Instandhaltung verändert  

NASA Astrophysics Data System (ADS)

Die zunehmende Komplexität von Produktionsanlagen und deren steigende Investitionssummen erfordern eine intensive Nutzung und überschaubare Folgekosten, zum Beispiel in der Instandhaltung. Um diese Ziele beim Investitionsvorgang von Anlagen effizienter als in der Vergangenheit zu gestalten sind Organisationsverfahren wie Life Cycle Cost Management (LCC-Management) bzw. Total Cost of Ownership (TCO) sinnvoll. Dieser Beitrag zeigt, wie Hersteller und Betreiber bis heute mit diesen Verfahren die Auslegung und das Betriebsverhalten von Anlagen entwickeln, deren reduzierten Instandhaltungsaufwand prognostizieren und die Leistungen zum Vorteil beider Vertragspartner steigern.

Zick, Manfred

381

Effects of ketoprofen for prevention of postoperative cognitive dysfunction in aged rats.  

PubMed

Postoperative cognitive dysfunction is a common geriatric complication that may be associated with increased mortality. Here, we investigated the effects of postoperative analgesia with ketoprofen on cognitive functions in aged animals and compared its effectiveness to morphine. Rats were randomly allocated to one of four groups: isoflurane anesthesia without surgery (group C), isoflurane anesthesia with laparotomy (group IL), and isoflurane anesthesia with laparotomy plus postoperative analgesia with ketoprofen or morphine. There was no difference in postoperative locomotor activity among groups. In group IL, postoperative pain levels assessed by the Rat Grimace Scale significantly increased until 8 h after surgery, which was similarly inhibited by both ketoprofen and morphine. Cognitive function was assessed using radial arm maze testing for 12 consecutive days from postoperative day 3. Results showed that the number of memory errors in group IL were significantly higher than those in goup C. However, both ketoprofen and morphine could attenuate the increase in memory errors following surgery to a similar degree. Conversely, ketoprofen showed no effect on cognitive function in the nonsurgical rats that did not experience pain. Our findings suggest that postoperative analgesia with ketoprofen can prevent the development of surgery-associated memory deficits via its pain-relieving effects. PMID:24676769

Kawano, Takashi; Takahashi, Tetsuya; Iwata, Hideki; Morikawa, Akihiro; Imori, Satoko; Waki, Sayaka; Tamura, Takahiko; Yamazaki, Fumimoto; Eguchi, Satoru; Kumagai, Naoko; Yokoyama, Masataka

2014-12-01

382

Genetics of pain perception, COMT and postoperative pain management in children  

PubMed Central

Background Effective perioperative analgesia is lacking for children owing to interindividual variations and underdosing of opioids caused by fear of adverse effects. We investigated the role of COMT SNPs on postoperative pain management in children. Methods One hundred and forty nine children undergoing adenotonsillectomy were enrolled. The associations of four COMT SNPs (rs6269, rs4633, rs4818 and rs4680) with postoperative pain were analyzed and outcome measures included maximum pain scores, need for postoperative opioid interventions and postoperative morphine requirements. Results We detected an association of postoperative opioid intervention need with all four COMT SNPs. Minor allele carriers of COMT SNPs were approximately three-times more likely to require analgesic interventions than homozygotes of major alleles (p-value range: 0.0031–0.0127; odds ratio range: 2.6–3.1). In addition, significant association was detected between maximum Face, Leg, Activity, Consolability, Cry (FLACC) pain scores and three COMT SNPs (rs6269, rs4633 and rs4680). Haplotype 1 (ATCA: 51.3%) and Haplotype 2 (GCGG: 36.2%) are more frequent. Haplotype 2 was associated with higher odds of intravenous analgesic intervention need in postanesthesia recovery unit with an odds ratio of 2.6 (95% CI: 1.2–5.4; p-value = 0.022). Conclusion COMT SNPs may play a significant role in interindividual variation in postoperative pain perception and postoperative morphine requirements in children. PMID:24533707

Sadhasivam, Senthilkumar; Chidambaran, Vidya; Olbrecht, Vanessa A; Esslinger, Hope R; Zhang, Kejian; Zhang, Xue; Martin, Lisa J

2014-01-01

383

Serumproteine und Aminosäuren in menschlicher Perilymphe  

Microsoft Academic Search

Zusammenfassung  \\u000a \\u000a \\u000a \\u000a 1. \\u000a \\u000a Post mortem entnommen menschliche Perilymphe wurde auf ihren Gehalt an Serumproteinfraktionen untersucht und mit Serum und\\u000a Liquor verglichen.\\u000a \\u000a \\u000a \\u000a \\u000a 2. \\u000a \\u000a Das Verteilungsmuster der Serumproteine in der Perilymphe unterscheidet sich deutlich von Serum und Liquor.\\u000a \\u000a \\u000a \\u000a \\u000a 3. \\u000a \\u000a Die in der Perilymphe nachgewiesenen Aminosuren gleichen weder dem Serum noch dem Liquor.\\u000a \\u000a \\u000a \\u000a \\u000a 4. \\u000a \\u000a Es wird der Schlu gezogen, da Perilymphe weder aus Serum

W. Giebel; H. Wespi

1973-01-01

384

Use of three evidence-based postoperative pain assessment practices by registered nurses.  

PubMed

To provide optimal postoperative pain relief, nursing practice should be based on the best evidence available. For over 20 years, results of studies regarding nurses' use of evidence-based practices, including postoperative pain assessment practices, have shown that nurses use the practices inconsistently. The present cross-sectional survey study was conducted to: 1) determine the extent to which registered nurses caring for postoperative patients experiencing pain used three evidence-based postoperative pain assessment practices; and 2) identify relationships among the level of adoption of evidence-based postoperative pain assessment practices and selected characteristics of registered nurses. Data were collected from a convenience sample of all nurses caring for adult postoperative patients in two Midwestern hospitals where 443 surveys (46.9%) were returned. Respondents were aware of, but not using, three evidence-based postoperative pain assessment practices consistently. Registered nurses who used multiple sources to identify solutions to clinical practice problems or read one or two professional journals regularly were more likely to have adopted the three evidence-based postoperative pain assessment practices. Registered nurses need to be encouraged to use multiple sources to identify solutions to clinical practice problems, including professional nursing journals. Innovative approaches to promote the application of research to education and practice settings are needed. It is important to identify opinion leaders, because opinion leaders are an important resource in overcoming the barriers so that adoption of pain of evidence-based postoperative pain assessment practices can proceed. Additional research is needed to identify what variables effect the adoption of evidence-based practices and identify interventions to improve the level of adoption. PMID:19944373

Carlson, Cathy L

2009-12-01

385

Preoperative factors predictive of complicated postoperative management after Roux-en-Y gastric bypass for morbid obesity  

Microsoft Academic Search

Introduction: This study was undertaken to determine preoperative predictive factors of complicated postoperative management after Roux-en-Y gastric bypass (RYGB) for morbid obesity. Methods: Between January 1999 and January 2002, 158 patients who underwent a RYGB received a standardized preoperative evaluation and data were collected prospectively. Complicated postoperative management was defined as patients requiring postoperative ICU admission for ?48 h, or

R. Gonzalez; S. P. Bowers; K. R. Venkatesh; E. Lin; C. D. Smith

2003-01-01

386

Preoperative importance of improvement and postoperative satisfaction in patients undergoing total hip replacement  

Microsoft Academic Search

Objective  We aimed to correlate the preoperative importance of improvement and postoperative satisfaction in patients undergoing total\\u000a hip replacement with the functional pre- and postoperative (12 months) status.\\u000a \\u000a \\u000a \\u000a \\u000a Method  Functional status was assessed by Western Ontario and McMasters Universities Osteoarthritis Index (WOMAC) and the preoperative\\u000a importance was rated for all WOMAC and 13 items of daily living. The postoperative satisfaction was assessed alongside

Torsten Schäfer; Sebastian Biakowski; Achim Walther; Stefan Fickert; Frank Krummenauer; Klaus-Peter Günther

2011-01-01

387

Adaptive and regulatory mechanisms in aged rats with postoperative cognitive dysfunction.  

PubMed

Inflammation may play a role in postoperative cognitive dysfunction. 5' Adenosine monophosphate-activated protein kinase, nuclear factor-kappa B, interleukin-1?, and tumor necrosis factor-? are involved in inflammation. Therefore, these inflammatory mediators may be involved in postoperative cognitive dysfunction. Western immunoblot analysis revealed 5' adenosine monophosphate-activated protein kinase and nuclear factor-kappa B in the hippocampus of aged rats were increased 1-7 days after splenectomy. Moreover, interleukin-1? and tumor necrosis factor-? were upregulated and gradually decreased. Therefore, these inflammatory mediators may participate in the splenectomy model of postoperative cognitive dysfunction in aged rats. PMID:25206851

Bi, Yanlin; Liu, Shuyun; Yu, Xinjuan; Wu, Mingshan; Wang, Mingshan; Wang, Yuelan

2014-03-01

388

Haptische Modellierung und Deformation einer Kugelzelle  

NASA Astrophysics Data System (ADS)

Haptische Simulationsmodelle dienen in der Medizin in erster Linie dem Training operativer Eingriffe. Sie basieren zumeist auf physikalischen Gewebemodellen, welche eine sehr genaue Simulation der biomechanischen Eigenschaften des betreffenden Gewebes erlauben, aber gleichzeitig sehr rechenintensiv und damit zeitaufwändig in der Ausführung sind. Die menschliche Wahrnehmung kann allerdings auch eine ungenaue haptische Modellierung psychooptisch ausgleichen. Daher kann es sinnvoll sein, haptische Simulationen auch mit nicht vollständig physikalisch definierten Deformationsmodellen durchzuführen. Am Beispiel der haptischer Simulation einer in-vitro Fertilisation wird gezeigt, dass durch die Anwendung eines geometrischen Deformationsmodells eine künstliche Befruchtung unter realistischen experimentellen Bedingungen in Echtzeit haptisch simuliert und damit trainiert werden kann.

Schippritt, Darius; Wiemann, Martin; Lipinski, Hans-Gerd

389

Postoperative Testing to Predict Recurrent Cushing Disease in Children  

PubMed Central

Context: Postoperative testing after transsphenoidal surgery (TSS) for Cushing disease (CD) in children and its usefulness in predicting residual disease or recurrence are not well studied. Objective: The objective of the study was to identify which one of three tests that are routinely performed in our institution after TSS performs better in the identification of noncured patients or predict relapse for CD. Design: This was a retrospective review of clinical data of 72 children who received surgery for CD (age range 5.8–18.3 yr). Setting: The study was conducted at a tertiary care center. Methods: After TSS, plasma ACTH and serum cortisol (at 0800 h), urinary free cortisol (UFC) values and an ovine CRH (oCRH) stimulation test were obtained. Patients were followed up for 24–120 months by a formal protocol. Results: Of 72 children with CD, 66 (94%) achieved sustained remission after TSS. Two children had persistent disease after TSS, whereas four children appeared cured at first but relapsed later. All four had low or undetectable UFCs that were not different from cured patients (P > 0.0.1). Children who remained in remission had significantly lower morning ACTH and cortisol levels after TSS compared with those who relapsed (P < 0.001). During an oCRH stimulation test, ACTH and cortisol values were higher in patients who relapsed vs. those in remission (P <0.001). Lack of histological confirmation of an adenoma, normal serum cortisol or ACTH, a normal response to oCRH, and glucocorticoid replacement for less than 6 months after surgery were associated with relapse. Conclusion: In pediatric patients with CD, low UFCs after TSS are not good predictors of sustained remission; morning ACTH and cortisol values and/or an oCRH test after TSS predicted patients that recurred. PMID:19470618

Batista, Dalia L.; Oldfield, Edward H.; Keil, Margaret F.; Stratakis, Constantine A.

2009-01-01

390

Hepatotoxicity after continuous amiodarone infusion in a postoperative cardiac infant.  

PubMed

A former 34-week-old female infant with Down syndrome underwent surgical correction of a congenital heart defect at 5 months of age. Her postoperative course was complicated by severe pulmonary hypertension and junctional ectopic tachycardia. Following treatment with amiodarone infusion, she developed laboratory indices of acute liver injury. At their peak, liver transaminase levels were 19 to 35 times greater than the upper limit of normal. Transaminitis was accompanied by coagulopathy, hyperammonemia, and high serum lactate and lipid levels. Hepatic laboratory abnormalities began to resolve within 48 hr of stopping amiodarone infusion. Heart rate control was achieved concurrently with discovery of laboratory test result abnormalities, and no further antiarrhythmic therapy was required. The intravenous formulation of amiodarone contains the diluent polysorbate 80, which may have hepatotoxic effects. Specifically, animal studies suggest that polysorbate 80 may destabilize cell membranes and predispose to fatty change within liver architecture. Polysorbate was implicated in infant fatalities from E-ferol use in the 1980s. This case illustrates a possible adverse event by the Naranjo probability scale. Given the extent of clinically apparent hepatic injury, this patient was not rechallenged with amiodarone during the remainder of her hospitalization. With amiodarone now used as first-line pharmacologic therapy for critical tachyarrhythmia in this population, the number of children exposed to this drug should be expected to increase. Laboratory indices of liver function should be evaluated at initiation of amiodarone therapy, as well as frequently throughout duration of therapy. Consideration should be given to polysorbate-free formulation of intravenous amiodarone for use in the cohort with congenital cardiac disease. PMID:23118673

Kicker, Jennifer S; Haizlip, Julie A; Buck, Marcia L

2012-04-01

391

Hepatotoxicity After Continuous Amiodarone Infusion in a Postoperative Cardiac Infant  

PubMed Central

A former 34-week-old female infant with Down syndrome underwent surgical correction of a congenital heart defect at 5 months of age. Her postoperative course was complicated by severe pulmonary hypertension and junctional ectopic tachycardia. Following treatment with amiodarone infusion, she developed laboratory indices of acute liver injury. At their peak, liver transaminase levels were 19 to 35 times greater than the upper limit of normal. Transaminitis was accompanied by coagulopathy, hyperammonemia, and high serum lactate and lipid levels. Hepatic laboratory abnormalities began to resolve within 48 hr of stopping amiodarone infusion. Heart rate control was achieved concurrently with discovery of laboratory test result abnormalities, and no further antiarrhythmic therapy was required. The intravenous formulation of amiodarone contains the diluent polysorbate 80, which may have hepatotoxic effects. Specifically, animal studies suggest that polysorbate 80 may destabilize cell membranes and predispose to fatty change within liver architecture. Polysorbate was implicated in infant fatalities from E-ferol use in the 1980s. This case illustrates a possible adverse event by the Naranjo probability scale. Given the extent of clinically apparent hepatic injury, this patient was not rechallenged with amiodarone during the remainder of her hospitalization. With amiodarone now used as first-line pharmacologic therapy for critical tachyarrhythmia in this population, the number of children exposed to this drug should be expected to increase. Laboratory indices of liver function should be evaluated at initiation of amiodarone therapy, as well as frequently throughout duration of therapy. Consideration should be given to polysorbate-free formulation of intravenous amiodarone for use in the cohort with congenital cardiac disease. PMID:23118673

Kicker, Jennifer S.; Haizlip, Julie A.; Buck, Marcia L.

2012-01-01

392

Zur frage der sexualbiologie und artzugehörigkeit von limax albipes dumont und mortillet (Limacidae, pulmonata)  

Microsoft Academic Search

1.Limax albipesDum. et Mort. erweist sich, und zwar in der Form montannsLeydig aus dem Trentin, als selbstandige Art durch die Form seiner Begattung.2.Dieser Begattungsmodus bildet eine einfachere Form des Typus, der sich bei L. cinereoniger und L. bielzi findet.3.Er hat nichts zu tun mit den Begattungstypen der Arten nut ungewöhnlich langem Penis (L. redii, L. gerhardti), ebensowenig aber mit dem

Ulrich Gerhardt

1938-01-01

393

zentrum Arbeits-, Sozial-, Umwelt-und Rechtsmedizin und Dermatologie ABTEIlUNG DERMATOlOGIE UND VENEROlOGIE  

E-print Network

@gwdg.de 39-6410 Mössner, Rotraut Dr. med. rmoessn@gwdg.de 39-6410 Forschungsschwerpunkte Psoriasis Atopische Primär-kutane Lymphome der Haut Research Foci Psoriasis Atopic Diseases, Mast-cells Malignant for these special diseases. 1. Psoriasis Die Schuppenflechte (Psoriasis) betrifft ca. 2% der Bevölke- rung und zeigt

Gollisch, Tim

394

Patient-specific semi-supervised learning for postoperative brain tumor segmentation.  

PubMed

In contrast to preoperative brain tumor segmentation, the problem of postoperative brain tumor segmentation has been rarely approached so far. We present a fully-automatic segmentation method using multimodal magnetic resonance image data and patient-specific semi-supervised learning. The idea behind our semi-supervised approach is to effectively fuse information from both pre- and postoperative image data of the same patient to improve segmentation of the postoperative image. We pose image segmentation as a classification problem and solve it by adopting a semi-supervised decision forest. The method is evaluated on a cohort of 10 high-grade glioma patients, with segmentation performance and computation time comparable or superior to a state-of-the-art brain tumor segmentation method. Moreover, our results confirm that the inclusion of preoperative MR images lead to a better performance regarding postoperative brain tumor segmentation. PMID:25333182

Meier, Raphael; Bauer, Stefan; Slotboom, Johannes; Wiest, Roland; Reyes, Mauricio

2014-01-01

395

Efficacy of Ibuprofen and Ibuprofen/Acetaminophen on Postoperative Pain in Symptomatic Necrotic Teeth.  

E-print Network

??The purpose of this prospective, randomized, double-blind study was to determine ibuprofen versus ibuprofen/acetaminophen usage for postoperative endodontic pain in symptomatic patients with a pulpal… (more)

Wells, Larry Kevin

2010-01-01

396

Ear-worn body sensor network device: an objective tool for functional postoperative home recovery monitoring  

PubMed Central

Patients' functional recovery at home following surgery may be evaluated by monitoring their activities of daily living. Existing tools for assessing these activities are labor-intensive to administer and rely heavily on recall. This study describes the use of a wireless ear-worn activity recognition sensor to monitor postoperative activity levels continuously using a Bayesian activity classification framework. The device was used to monitor the postoperative recovery of five patients following abdominal surgery. Activity was classified into four groups ranging from very low (level 0) to high (level 3). Overall, patients were found to be undertaking a higher proportion of level 0 activities on postoperative day 1 which was gradually replaced by higher-level activities over the next 3?days. This study demonstrates how a pervasive healthcare technology can objectively monitor functional recovery in the unsupervised home setting. This may be a useful adjunct to existing postoperative monitoring systems. PMID:21252051

Atallah, Louis; Lo, Benny; Gray, Edward; Athanasiou, Thanos; Darzi, Ara; Yang, Guang-Zhong

2011-01-01

397

Comparison of extensive brain calcification in postoperative hypoparathyroidism on CT and NMR scan  

Microsoft Academic Search

A case of postoperative hypoparathyroidism is presented in which calcifications seen on CT scan were differently visualized on T2 weighted NMR images. High and low signal intensities may reflect different stages of the calcifiying process thus confirming neuropathological findings.

C. Lang; W. Huk; J. Pichl

1989-01-01

398

Effect of preoperative abstinence on poor postoperative outcome in alcohol misusers: randomised controlled trial  

Microsoft Academic Search

Objective To evaluate the influence of preoperative abstinence on postoperative outcome in alcohol misusers with no symptoms who were drinking the equivalent of at least 60 g ethanol\\/day. Design Randomised controlled trial.

Hanne Tnnesen; Jacob Rosenberg; Hans J Nielsen; Verner Rasmussen; Christina Hauge; Ib K Pedersen; Henrik Kehlet

399

Tuning in To Music May Ease Kids' Post-Op Pain  

MedlinePLUS

... this page, please enable JavaScript. Tuning In to Music May Ease Kids' Post-Op Pain, Study Finds ... pain for children, but listening to their favorite music might help ease their discomfort, a new study ...

400

Liver Planning Software Accurately Predicts Postoperative Liver Volume and Measures Early  

E-print Network

Liver Planning Software Accurately Predicts Postoperative Liver Volume and Measures Early or remnant liver volume (RLV) after hepatic resection is a critical predictor of perioperative outcomes. This study investigates whether the accuracy of liver surgical plan- ning software for predicting

Miga, Michael I.

401

Reduction of postoperative mortality and morbidity with epidural or spinal anaesthesia: results from overview of randomised  

Microsoft Academic Search

Objectives To obtain reliable estimates of the effects of neuraxial blockade with epidural or spinal anaesthesia on postoperative morbidity and mortality. Design Systematic review of all trials with randomisation to intraoperative neuraxial blockade or not.

Anthony Rodgers; Natalie Walker; S Schug; A McKee; H Kehlet; A van Zundert; D Sage; M Futter; G Saville; T Clark; S MacMahon

2000-01-01

402

Fish Oil and Post-Operative Atrial Fibrillation – Results of the Omega-3 Fatty Acids for Prevention of Post-Operative Atrial Fibrillation (OPERA) Trial  

PubMed Central

Context Post-operative atrial fibrillation/flutter (AF) is one of the most common complications of cardiac surgery and significantly increases morbidity and healthcare utilization. A few small trials have evaluated whether long-chain n-3-polyunsaturated fatty acids (PUFA) reduce post-op AF, with mixed results. Objective To determine whether peri-operative n-3-PUFA supplementation reduces post-op AF. Design Randomized, double-blind, placebo-controlled, multinational, clinical trial. Patients A total of 1,516 patients scheduled for cardiac surgery across 28 centers in the US, Italy, and Argentina, enrolled between Aug 2010 and Jun 2012. Inclusion criteria were broad; the main exclusions were regular use of fish oil or absence of sinus rhythm at enrollment. Forty-eight percent of screened patients and 94% of eligible patients were enrolled. Intervention Patients were randomized to receive fish oil (1 g capsules containing ?840 mg n-3-PUFA as ethyl esters) or placebo, with pre-operative loading of 10g over 3-5 days (or 8g over 2 days) followed post-operatively by 2g/d until hospital discharge or post-op day10, whichever first. Main Outcome Measures The primary endpoint was occurrence of post-op AF >30 sec. We also evaluated post-op AF lasting >1hr, resulting in symptoms, or treated with cardioversion; other secondary post-op AF endpoints; other tachyarrhythmias; hospital utilization; and major adverse cardiovascular events, 30-day mortality, bleeding, and other adverse events. All endpoints and analyses plans were prespecified. Results At enrollment, mean±SD age was 64±13 years, 72.2% were male, and 51.8% had planned valvular surgery. The primary endpoint occurred in 233 (30.7%) and 227 (30.0%) patients assigned to placebo and n-3-PUFA, respectively (OR=0.96, 95%CI=0.77-1.20; P=0.74). None of the secondary endpoints were significantly different, including post-op AF that was sustained, symptomatic, or treated (n=231 [30.5%] vs. n=224 [29.6%], P=0.70) or number of post-op AF episodes per patient (1 episode: n=220 [29.0%] vs. n=217 [28.6%]; 2 episodes: n=156 [20.6%] vs. n=157 [20.7%]; 3+ episodes: n=18 [2.4%] vs. n=21 [2.8%]; P=0.73). n-3-PUFA was generally well-tolerated, with no evidence for increased risk of bleeding or serious adverse events. Conclusions In this large multinational trial among patients undergoing cardiac surgery, peri-operative supplementation with n-3-PUFA, compared to placebo, did not reduce the risk of post-operative AF. PMID:23128104

Mozaffarian, Dariush; Marchioli, Roberto; Macchia, Alejandro; Silletta, Maria G.; Ferrazzi, Paolo; Gardner, Timothy J.; Latini, Roberto; Libby, Peter; Lombardi, Federico; O’Gara, Patrick T.; Page, Richard L.; Tavazzi, Luigi; Tognoni, Gianni

2013-01-01

403

Impact of variability among surgeons on postoperative morbidity and mortality and ultimate survival  

Microsoft Academic Search

OBJECTIVE--To assess the differences among surgeons in postoperative complications, postoperative mortality, and survival in patients undergoing surgery for colorectal cancer. DESIGN--Prospective study of patients with colorectal cancer managed by one of 13 consultant surgeons, none of whom had a special interest in colorectal surgery. SETTING--Royal Infirmary, Glasgow. PATIENTS--645 sequential patients with colorectal cancer presenting over the six years from 1974

C S McArdle; D Hole

1991-01-01

404

Patient-controlled intranasal analgesia (PCINA) for the management of postoperative pain: a pilot study  

Microsoft Academic Search

Study Objective: To compare patient-controlled intranasal analgesia (PCINA) for postoperative pain management with ward-provided pain therapy.Design: Randomized, prospective pilot study.Setting: University medical center.Patients: 20 ASA status I and II orthopedic patients.Interventions: On the first postoperative day, 20 patients were randomized to receive either PCINA for 4 hours followed by 5 hours of ward-provided pain therapy (Group 1; n = 10)

H. Walter Striebel; Thomas Olmann; Claudia Spies; Glenda Brummer

1996-01-01

405

Propofol anaesthesia reduces early post-operative emesis after paediatric strabismus surgery  

Microsoft Academic Search

Propofol anaesthesia may reduce postoperative emesis. The purpose of this study was to compare the incidence of emesis after\\u000a propofol anaesthesia with and without nitrous oxide, compared with thiopentone and halothane anaesthesia, in hospital and\\u000a up to 24 hr postoperatively, in outpatient paediatric patients after strabismus surgery. Seventy-five ASA class I or II, unpremedicated\\u000a patients, aged 2–12 yr were randomly

Eleanor J. Reimer; Carolyne J. Montgomery; Joan C. Bevan; Pamela M. Merrick; Derek Blackstock; Vladan Popovic

1993-01-01

406

Prior conditions influencing nurses' decisions to adopt evidence-based postoperative pain assessment practices.  

PubMed

Over the past 30 years, postoperative pain relief has been shown to be inadequate. To provide optimal postoperative pain relief, it is imperative for nurses to use evidence-based postoperative pain assessment practices. This correlational descriptive study was conducted to identify factors, termed prior conditions, that influenced nurses' decisions to adopt three evidence-based postoperative pain assessment practices. A convenience sample of nurses who cared for adult postoperative patients in two Midwestern hospitals were surveyed, and 443 (46.9%) nurses responded. The previous practice and innovativeness of nurses were supportive of adoption of the three practices. Nurses felt that patients received adequate pain relief, which is unsupportive of adoption of the three practices because there is no impetus to change. Nurses who perceived the prior conditions as being supportive of adoption of pain management practices used multiple sources to identify solutions to clinical practice problems, and those who read professional nursing journals were more likely to have adopted the three practices and were more innovative. The number of sources used to identify solutions to clinical practice problems, previous practices, and innovativeness were predictive of nurses' adoption of the three evidence-based postoperative pain assessment practices. Nurses need to be encouraged to use multiple sources, including professional nursing journals, to identify solutions to clinical practice problems. Innovative nurses may be considered to be opinion leaders and need to be identified to promote the adoption of evidence-based postoperative pain assessment practices. Further exploration of the large unexplained variance in adoption of evidence-based postoperative pain assessment practices is needed. PMID:21095599

Carlson, Cathy L

2010-12-01

407

Oral valdecoxib and injected parecoxib for acute postoperative pain: a quantitative systematic review  

Microsoft Academic Search

BACKGROUND: Clinical trials suggest that cyclo-oxygenase-2 specific inhibitors (coxibs) are an effective treatment for acute postoperative pain. The aims of this systematic review were to examine the evidence for oral valdecoxib and injected parecoxib, and quantify efficacy and adverse effects. METHODS: Information from randomized, double-blind studies in acute postoperative pain was sought. The area under the pain relief versus time

Jodie Barden; Jayne E Edwards; Henry J McQuay; R Andrew Moore

2003-01-01

408

Gabapentin and postoperative pain: a qualitative and quantitative systematic review, with focus on procedure  

Microsoft Academic Search

BACKGROUND: Gabapentin is an antiepileptic drug used in a variety of chronic pain conditions. Increasing numbers of randomized trials indicate that gabapentin is effective as a postoperative analgesic. This procedure-specific systematic review aims to analyse the 24-hour postoperative effect of gabapentin on acute pain in adults. METHODS: Medline, The Cochrane Library and Google Scholar were searched for double-blind randomized placebo

Ole Mathiesen; Steen Møiniche; Jørgen B Dahl

2007-01-01

409

Ultrasound-guided continuous quadratus lumborum block for postoperative analgesia in a pediatric patient.  

PubMed

Quadratus lumborum block is a recently introduced variation of transversus abdominis plane block. In this report, we describe the use of ultrasound-guided continuous quadratus lumborum block for postoperative analgesia in a 7-year-old child scheduled to undergo radical nephrectomy (left-sided) for Wilms tumor. The result was excellent postoperative analgesia and minimal requirement for rescue analgesics. The modification described may allow easier placement of a catheter for continuous infusion of local anesthetic. PMID:25642956

Chakraborty, Arunangshu; Goswami, Jyotsna; Patro, Viplab

2015-02-01

410

Intramuscular tramadol versus ketorolac in patients with orthopedic and traumatologic postoperative pain: a comparative multicenter trial  

Microsoft Academic Search

This 3-day, multicenter, open-label, randomized, controlled trial was undertaken to assess the postoperative analgesic effect and therapeutic safety of intramuscular tramadol compared with intramuscular ketorolac in 48 patients undergoing orthopedic surgery and having postoperative pain assessed as 75 mm or more on a 100-mm visual analogue scale. Tramadol (100 mg\\/2 mL ampules) was administered as needed to a maximum of

Albino Lanzetta; Mariella Vizzardi; Giuseppe Letizia; Umberto Martorana; Antonio Sanfilippo; Leonardo Osti; Carlo Cervelli; Renato Coluccia

1998-01-01

411

High-dose-rate postoperative vaginal cuff irradiation alone for stage Ib and Ic endometrial cancer  

Microsoft Academic Search

Purpose: To evaluate the effectiveness of postoperative high-dose-rate (HDR) vaginal cuff irradiation alone (1500 cGy in 3 fractions) in patients with Stage Ib and Ic endometrial cancer.Methods and Materials: This is a retrospective review of 102 patients with Stage Ib and Ic endometrial cancer treated with a hysterectomy and postoperative HDR intracavitary therapy alone during the period of 1\\/1\\/90–12\\/31\\/96. Each

John M Anderson; Baldassarre Stea; Alton V Hallum; Edward Rogoff; Joel Childers

2000-01-01

412

Postoperative swallowing function after posterior fossa tumor resection in pediatric patients  

Microsoft Academic Search

Objective  After tumor resection involving the posterior fossa, postoperative swallowing dysfunction may be anticipated. This retrospective study was designed to document swallowing abnormalities in children after posterior fossa brain tumor surgery and to recommend management approaches for children at risk for aspiration.Methods  Twenty-four children referred postoperatively for a video fluoroscopic swallow study (VFSS) out of 127 children undergoing posterior fossa surgery for

Lisa A. Newman; Frederick A. Boop; Robert A. Sanford; Jerome W. Thompson; Carrie K. Temple; Christopher D. Duntsch

2006-01-01

413

www.law.und.edu GRAND FORKS  

E-print Network

interest in the University of North Dakota School of Law. As you weigh choosing among the more than 200 law CONTENTS #12;2 The University of North Dakota School of Law THE UND SCHOOL OF LAW Founded in 1899 and steeped in rich tradition, the University of North Dakota School of Law blends an innovative education

Delene, David J.

414

Universittsmedizin Gttingen Publikationen und Hochschulschriften 2008  

E-print Network

for Health - International Interoperability. In: Gesellschaft f. Versicherungswissenschaft u. -gestaltung e funktionsdiagnostischer Referenzwerte. GMS Med Inform Biom Epidemiol, 08gmds249: 64-66. 3. Canisius S, Viezens F, Hornung U (2008) Grid Computing und die Zukunft der IT im Gesundheitswesen. GMS Med Inform Biom Epidemiol

Gollisch, Tim

415

Einfhrungsveranstaltungen der Agrar-und Umweltwissenschaftlichen Fakultt  

E-print Network

- Agrar- und Umweltwissenschaftliche Fakultät | Universität Rostock | Justus-von-Liebig-Weg 6 | 18059 Anmeldung ist am 08.10.2012 im Rahmen der Eröffnungsveranstaltung möglich. Campus-Innenhof Justus-von-Liebig

Wolkenhauer, Olaf

416

Die Darwinsche Theorie und die Eukaryoten  

E-print Network

Geologe Charles Darwin 1859 in der Darwin Theorie. 6.1 Die Darwin-Theorie der Evolution Lebewesen kämpfen Darwin-Theorie zugrunde liegt, bereits in der präbiotischen Welt. Dort trägt es zur chemischen Evolution eine gewaltige Evolution statt. Diese Entwicklung des Lebens beschrieb der englische Biologe und

Ulmschneider, Peter

417

Algorithmen und Datenstrukturen Wagner/Willhalm  

E-print Network

Programm cvs vertraut (http://www.gnu. org/manual/cvs/index.html) und setzt es in eurem Projekt ein. Einen CVS-Server braucht ihr nicht aufzusetzen, da die Projekt-Teilnehmer nicht ¨uber das Netz verstreut-Mitglieder Schreibrechte haben. ¨Uber die Umgebungsvariable CVSROOT kann man den Ort dieses Verzeichnisses cvs bekannt

Brandes, Ulrik

418

STRUKTURELLE GRUNDLAGEN UND MECHANIK VON ZYTOGELEN  

E-print Network

Naturwissenschaften Vorgelegt im Fachbereich Biologie der Johann Wolfgang Goethe-Universität in Frankfurt am Main von Oliver Wagner aus Köln Frankfurt 2000 (DF1) #12;ii vom Fachbereich Biologie der Johann Wolfgang GoetheSTRUKTURELLE GRUNDLAGEN UND MECHANIK VON ZYTOGELEN Dissertation zur Erlangung des Doktorgrades der

Wagner, Oliver

419

Verstehen und Verarbeiten von Bildern J. Baumeister  

E-print Network

Fachbereich Mathematik Johann Wolfgang Goethe ­ Universit¨at, Robert Mayer Strasse 6 ­ 10, D 60054 FrankfurtVerstehen und Verarbeiten von Bildern J. Baumeister 2. Mai 2000 Zusammenfassung: Mit der Zunahme der Rechnerleistung moderner Computer gewinnt die digi- tale Verarbeitung von Bildern eine

Baumeister, Johann

420

{HAUPTBEITRAG / INTEGRALRECHNUNG UND COMPUTERALGEBRA IntegralrechnungundComputeralgebra  

E-print Network

Archimedes (282­212 v. Chr.), der die Flächen- und Volumenbestimmung, die Abb.1 Archimedes von Syrakus die = r2 . Es war die Erkenntnis von Archimedes von Syra- kus, dass die beiden Proportionalitätskonstanten übereinstimmen: = . Diese Zahl ist eine der berühmtesten Naturkonstanten. Archimedes approximierte die Zahl

Koepf, Wolfram

421

Is Early Enteral Nutrition Better for Postoperative Course in Esophageal Cancer Patients?  

PubMed Central

We retrospectively examined esophageal cancer patients who received enteral nutrition (EN) to clarify the validity of early EN compared with delayed EN. A total of 103 patients who underwent transthoracic esophagectomy with three-field lymphadenectomy for esophageal cancer were entered. Patients were divided into two groups; Group E received EN within postoperative day 3, and Group L received EN after postoperative day 3. The clinical factors such as days for first fecal passage, the dose of postoperative albumin infusion, differences of serum albumin value between pre- and postoperation, duration of systematic inflammatory response syndrome (SIRS), incidence of postoperative infectious complication, and use of total parenteral nutrition (TPN) were compared between the groups. The statistical analyses were performed using Mann-Whitney U test and Chi square test. The statistical significance was defined as p < 0.05. Group E showed fewer days for the first fecal passage (p < 0.01), lesser dose of postoperative albumin infusion (p < 0.01), less use of TPN (p < 0.01), and shorter duration of SIRS (p < 0.01). However, there was no significant difference in postoperative complications between the two groups. Early EN started within 3 days after esophagectomy. It is safe and valid for reduction of albumin infusion and TPN, for promoting early recovery of intestinal movement, and for early recovery from systemic inflammation. PMID:24067386

Kobayashi, Kazuaki; Koyama, Yu; Kosugi, Shin-ichi; Ishikawa, Takashi; Sakamoto, Kaoru; Ichikawa, Hiroshi; Wakai, Toshifumi

2013-01-01

422

Two-step oblique incision during 25-gauge vitrectomy reduces incidence of postoperative hypotony.  

PubMed

The efficacy of a two-step, oblique incision procedure during 25-gauge vitrectomy on postoperative hypotony was evaluated by a retrospective, case-control study. The transconjunctival incision during 25-gauge vitrectomy was made in two steps: penetration with a microvitreoretinal blade followed by a penetrater instrument of a blunt trocar. The two-step procedure was performed on 89 eyes and with the conventional incision on 68 eyes. The incidence of hypotony (intraocular pressure <6 mmHg) on the first postoperative day and after 1 week and 1 month was compared. Hypotony was found in two eyes (2%) with the two-step method and 12 eyes (18%) with the conventional incision on the first postoperative day (P = 0.001, Fisher's exact probability test). The preoperative intraocular pressure was not significantly different in the two groups but was significantly higher in the two-step group than in the conventional method group on the first postoperative day (P = 0.001, Wilcoxon rank test). Twenty-five-gauge vitrectomy with two-step oblique incisions will reduce the incidence of postoperative hypotony on the first postoperative day. PMID:17997769

Inoue, Makoto; Shinoda, Kei; Shinoda, Hajime; Kawamura, Ryosuke; Suzuki, Kotaro; Ishida, Susumu

2007-11-01

423

Clinical parameters affecting prediction accuracy of postoperative lung function in non-small cell lung cancer.  

PubMed

Despite significant development in chemotherapy and radiotherapy, surgery is still the cornerstone for curative lung cancer treatment. Accurate prediction of postoperative lung function is mandatory. The goal of this study was to identify important clinical factors affecting prediction accuracy of postoperative lung function for more careful patient selection. The medical records of non-small cell lung cancer patients undergoing pulmonary resection were reviewed. An accuracy index, apo/ppoFEV(1) was defined as the ratio of actual postoperative FEV(1) [apoFEV(1)] to predicted postoperative FEV(1) [ppoFEV(1)]. We used multivariate analysis to inspect the relationship between the accuracy index and seven tentative clinical factors: age, gender, preoperative FEV(1), time interval between operation and the first postoperative FEV(1), bronchodilator response (%), resected lung portion, and the number of resected lung segments. A total of 82 patients were analyzed. Accuracy index of quantitative perfusion lung scan-based prediction was better than that of simple calculation. Multivariate analysis identified the number of resected lung segments and preoperative FEV(1) as the significant clinical factors affecting the accuracy index (P=0.026 and 0.002, respectively). Preoperative FEV(1) and the number of resected lung segments are significant clinical factors affecting prediction accuracy of postoperative lung function. PMID:18687696

Kim, Jwa-Kyung; Jang, Seung Hun; Lee, Jae Woong; Kim, Dong-Gyu; Hong, Ki Woo; Jung, Ki-Suck

2008-12-01

424

Using the Mouse Grimace Scale to reevaluate the efficacy of postoperative analgesics in laboratory mice.  

PubMed

Postoperative pain management in animals is complicated greatly by the inability to recognize pain. As a result, the choice of analgesics and their doses has been based on extrapolation from greatly differing pain models or the use of measures with unclear relevance to pain. We recently developed the Mouse Grimace Scale (MGS), a facial-expression-based pain coding system adapted directly from scales used in nonverbal human populations. The MGS has shown to be a reliable, highly accurate measure of spontaneous pain of moderate duration, and therefore is particularly useful in the quantification of postoperative pain. In the present study, we quantified the relative intensity and duration of postoperative pain after a sham ventral ovariectomy (laparotomy) in outbred mice. In addition, we compiled dose-response data for 4 commonly used analgesics: buprenorphine, carprofen, ketoprofen, and acetaminophen. We found that postoperative pain in mice, as defined by facial grimacing, lasts for 36 to 48 h, and appears to show relative exacerbation during the early dark (active) photophase. We find that buprenorphine was highly effective in inhibiting postoperative pain-induced facial grimacing in mice at doses equal to or lower than current recommendations, that carprofen and ketoprofen are effective only at doses markedly higher than those currently recommended, and that acetaminophen was ineffective at any dose used. We suggest the revision of practices for postoperative pain management in mice in light of these findings. PMID:22330867

Matsumiya, Lynn C; Sorge, Robert E; Sotocinal, Susana G; Tabaka, John M; Wieskopf, Jeffrey S; Zaloum, Austin; King, Oliver D; Mogil, Jeffrey S

2012-01-01

425

Influence of preoperative emotional state on postoperative pain following orthopedic and trauma surgery  

PubMed Central

OBJECTIVES: to analyze the relationship between preoperative emotional state and the prevalence and intensity of postoperative pain and to explore predictors of postoperative pain. METHOD: observational retrospective study undertaken among 127 adult patients of orthopedic and trauma surgery. Postoperative pain was assessed with the verbal numeric scale and with five variables of emotional state: anxiety, sweating, stress, fear, and crying. The Chi-squared test, Student's t test or ANOVA and a multivariate logistic regression analysis were used for the statistical analysis. RESULTS: the prevalence of immediate postoperative pain was 28%. Anxiety was the most common emotional factor (72%) and a predictive risk factor for moderate to severe postoperative pain (OR: 4.60, 95% CI 1.38 to 15.3, p<0.05, AUC: 0.72, 95% CI: 0.62 to 0.83). Age exerted a protective effect (OR 0.96, 95% CI: 0.94-0.99, p<0.01). CONCLUSION: preoperative anxiety and age are predictors of postoperative pain in patients undergoing orthopedic and trauma surgery. PMID:25493674

Robleda, Gemma; Sillero-Sillero, Amalia; Puig, Teresa; Gich, Ignasi; Baños, Josep-E

2014-01-01

426

Definitive Radiotherapy versus Postoperative Radiotherapy of Patients with Oro- and Hypopharyngeal Cancer: Impact of Prognostic Factors  

PubMed Central

Purpose. To compare the impact of prognostic factors of patients treated with definitive radio(chemo)therapy versus patients treated with surgery and postoperative radiotherapy for squamous cell carcinoma of the oro- and hypopharynx. Patients and Methods. 162 patients treated with definitive radiotherapy and 126 patients treated with postoperative radiotherapy were retrospectively analysed. The impact of the prognostic factors gender, age, total tumor volume (TTV), pre-radiotherapy hemoglobin level (Hb-level), tumor site, T- and N-classification, radiotherapy interruptions >5 days, radiotherapy versus simultaneous radiochemotherapy, R-status and time interval between surgery and radiotherapy were investigated. Results. The median follow-up time for the censored patients treated with definitive radio(chemo)therapy was 28.5 months and for postoperative radiotherapy 36.5 months. On univariate analysis, the TTV, Hb-level, and simultaneous radiochemotherapy had a significant impact on the survival of patients treated with definitive radio(chemo)therapy. For patients treated with postoperative radiotherapy, only the TTV showed a statistical trend for the survival (P = 0.13). On multivariate analysis, the TTV and simultaneous radiochemotherapy maintained their statistical significance for patients treated with definitive raditherapy, and the TTV, the statistical trend for patients treated with postoperative radiotherapy (P = 0.19). Conclusions. The TTV was the predominant prognostic factor for both, patients treated with definitive or postoperative radiotherapy. PMID:22315594

Rudat, Volker; Ahmet-Osman, Salia; Schramm, Oliver; Dietz, Andreas

2012-01-01

427

A Comparison of Three Methods for Postoperative Pain Control in Patients Undergoing Arthroscopic Shoulder Surgery  

PubMed Central

Background Arthroscopic shoulder operations (ASS) are often associated with severe postoperative pain. Nerve blocks have been studied for pain in shoulder surgeries. Interscalene brachial plexus blocks (ISB) and an intra-articular injection (IA) have been reported in many studies. The aim of the present study is to evaluate the effect of ISB, a continuous cervical epidural block (CCE) and IA as a means of postoperative pain control and to study the influence of these procedures on postoperative analgesic consumption and after ASS. Methods Fifty seven patients who underwent ASS under general anesthesia were randomly assigned to one of three groups: the ISB group (n = 19), the CCE group (n = 19), and the IA group (n = 19). Patients in each group were evaluated on a postoperative numerical rating scale (NRS), their rescue opioid dosage (ROD), and side effects. Results Postoperative NRSs were found to be higher in the IA group than in the ISB and CCE groups both at rest and on movement. The ROD were 1.6 ± 2.3, 3.0 ± 4.9 and 7.1 ± 7.9 mg morphine equivalent dose in groups CCE, ISB, and IA groups (P = 0.001), respectively, and statistically significant differences were noted between the CCE and IA groups (P = 0.01) but not in between the ISB and CCE groups. Conclusions This prospective, randomized study demonstrated that ISB is as effective analgesic technique as a CCE for postoperative pain control in patients undergoing ASS. PMID:25589946

Park, Sun Kyung; Choi, Sung Wook; Song, Sung Wook

2015-01-01

428

Effect of incision size on early postoperative visual rehabilitation after cataract surgery and intraocular lens implantation.  

PubMed

One hundred fifty-one unilateral cataract patients were randomly assigned to receive either a one-piece Staar AA-4203 silicone intraocular lens inserted through a 3.5 mm incision, an loptex 5 mm x 6 mm oval optic lens inserted through a 5.5 mm incision, or an AMO three-piece modified C-loop 6.0 round optic poly(methyl methacrylate) lens inserted through a 6.5 mm incision. Follow-up was 97% at two days postoperatively and 84% at one week and two months postoperatively. At one week postoperatively, 62% of 3.5 mm incision cases had uncorrected visual acuity of 20/40 or better compared with 33% of 5.5 mm (P < .01) and 43% of 6.5 mm incision cases. At two months postoperatively, 85% of 3.5 mm incision cases had uncorrected visual acuity of 20/40 or better compared with 64% of 6.5 mm (P < .05) and 71% of 5.5 mm incision cases. The 3.5 mm incision cases had significantly less total keratometric cylinder than other cases at all postoperative examinations (P < or = .001) and less surgically induced cylinder at two days and one week post-operatively (P < or = .02). The 5.5 mm and 6.5 mm incision cases did not differ significantly in visual acuity or astigmatism at any examination. PMID:8355156

el-Maghraby, A; Anwar, M; el-Sayyad, F; Matheen, M; Marzouky, A; Gazayerli, E; Salah, T; Ballew, C

1993-07-01

429

Continuous ropivacaine infusion vs transdermal fentanyl for providing postoperative analgesia following temporomandibular joint interpositional gap arthroplasty  

PubMed Central

Aim The purpose of this study was to evaluate the postoperative pain control and mouth opening in patients undergoing temporomandibular joint interpositional gap arthroplasty by either placing an epidural catheter in the incision wound and infusing ropivacaine 0.25% or by using a transdermal fentanyl patch. Materials and Methods: The study was prospective, randomized and double blind. Eighty patients belonging to American Society of Anesthesiologists grade I and II, 18–32 years of age, scheduled for temporomandibular joint interpositional gap arthroplasty were randomized into 2 groups; ropivacaine group (G rop): to receive 0.25% ropivacaine infusion and transdermal fentanyl group (G tf): to receive transdermal fentanyl patch. For postoperative pain (Visual Analog Score [VAS]) and analgesic requirements were assessed 2, 4 and 8 h after surgery and each morning, until and 4 days after surgery. Results: Time to first analgesic requirement was found to be significantly (P < 0.0001) higher in G rop (49 ± 6.7) as compared with G tf (32 ± 9.1) VAS were also significantly lower in G rop throughout the postoperative period. Postoperatively, mouth opening was better in G rop as compared with G tf, which was statistically significant. Conclusion: It was concluded that by placing an epidural catheter at the incision wound and continuously infusing with ropivacaine 0.25% effectively controls the postoperative pain in patients undergoing temporomandibular joint interpositional gap arthroplasty and provides better postoperative mouth opening. PMID:22442580

Dhasmana, Satish; Singh, Vibha; Pal, U.S.

2010-01-01

430

Causes and managements of postoperative complications after degenerative scoliosis treatments with internal fixation  

PubMed Central

Objective: To investigate the causes and managements of early postoperative complications of degenerative scoliosis (DS) treated with internal pedicle screw fixation. Methods: From Jan 2000 to Apr 2013, 325 DS patients treated with internal pedicle screw fixation in our hospital were retrospectively involved. The categories, causes, managements and outcomes of early postoperative complications were statistically analyzed. Results: Early postoperative complications occurred in 10.76% of the patients including 16 cases of lower limb numb or pain, 6 cases of decreased lower limb sensitivity and motor functions, which accounted for 62.86% of all complications, followed by incision infections (4/35, 11.43%) and rare cases of cerebrospinal fluid leakage, cardiac and renal inadequacy, urinary system and pulmonary infections. The incidence of overall complications (19.79%, p = 0.001) and nerve injuries (11.46%, p = 0.000) were significantly higher in long-segment than in short-segment fixations. Improper screw implanting, over correction of scoliosis and insufficient blood supply of the spinal cord during operation were risk factors for early postoperative complications and most of them were cured by anti-infection medication, incision dressing change, nerve nourishment, adjusting the screws and anti-osteoporosis treatments within 6 months after surgery. Only three cases with severe nerve injury did not improve until the 6 months postoperative follow-up. Conclusions: Most of the postoperative complications in our DS patients disappeared within 6 months after surgery and more than half of complications were nerve injuries.

Yang, Yong-Hong; Zheng, Jie; Lou, Shu-Liang

2014-01-01

431

Safety of liposome extended-release bupivacaine for postoperative pain control  

PubMed Central

Background: Ideal postoperative pain management requires a multidisciplinary approach in combination with a variety of dosage regimens. Approximately 21–30% of patients experience moderate to severe pain in the postoperative period, which may have a significant impact on recovery rate, standard of living, psychological health, and postoperative complications. Objective: Analysis of the incidence and characterization of reported adverse effects with DepoFoam bupivacaine compared to conventional bupivacaine or placebo. Methods: A systematic review of prospective studies on the use of DepoFoam versus bupivacaine or placebo was performed in order to answer the clinically relevant question: is DepoFoam a safer formulation in place of bupivacaine single injection or continuous local infusion techniques for postoperative pain management? Inclusion criteria required randomized, controlled, double-blind trials in patients 18 years old or older, single dose used for postoperative pain control, and a primary procedure performed. Results: Six studies fitted the inclusion criteria for analysis, DepoFoam bupivacaine used in therapeutic doses was well-tolerated, had a higher safety margin, and showed a favorable safety profile compared to bupivacaine and control groups. Conclusion: Extended drug delivery system DepoFoam bupivacaine is a promising drug formulation that may significantly improve postoperative care and pain control in surgical patients. PMID:24817851

Portillo, Juan; Kamar, Nawal; Melibary, Somayah; Quevedo, Eduardo; Bergese, Sergio

2014-01-01

432

Bildung, Phasentransfer und Toxizität halogenierter Desinfektionsnebenprodukte im Aufbereitungszyklus von Schwimmbeckenwasser - Schwerpunkt stickstoffhaltige Verbindungen.  

E-print Network

??In dieser Dissertation wurden Bildungsbedingungen von stickstoffhaltigen Desinfektionsnebenprodukten (DNP) im Schwimmbeckenwasser und deren Verteilung in die Luft von Hallenschwimmbädern untersucht. Die Stoffklasse der Chloramine und… (more)

Schmalz, Christina

2012-01-01

433

Bildungstheoretische und entwicklungsadäquate Grundlagen als Kriterien für die Gestaltung von Mathematikunterricht am Gymnasium.  

E-print Network

??Die Diskussion um die Vermittlungs- und Verständnisprobleme im Mathematikunterricht bilden den Ausgangspunkt der vorliegenden Arbeit. Unter Bezugnahme auf Klassiker der Bildungs- und Entwicklungstheorie werden Kriterien… (more)

Möhringer, Jutta

2006-01-01

434

Früh- und Differentialdiagnose von Parkinson-Syndromen unter besonderer Berücksichtigung des Steele-Richardson-Olszewski-Syndroms.  

E-print Network

??In der Differentialdiagnose von Parkinson-Syndromen wurden in frühen und in fortgeschrittenen Stadien insgesamt 138 Patienten mit der Verdachtsdiagnose eines Morbus Parkinson und mit der Verdachtsdiagnose… (more)

Arnold, Guy

2001-01-01

435

Der Einsatz von Lactoferrin und Epigallocatechingallat in der Prophylaxe parodontaler Erkrankungen der Katze.  

E-print Network

??Parodontopathien sind die am häufigsten vorkommenden Erkrankungen von Hund und Katze. Vor allem bei Katzen beschränken sich Prophylaxemaßnahmen häufig auf eine wiederholte Plaque- und Zahnsteinentfernung… (more)

Gorissen, Sonja

2004-01-01

436

Zur stoffwechselphysiologischen bedeutung von mannit und trehalose in Agaricus bisporus (Eine gaschromatographische studie)  

Microsoft Academic Search

Es wird eine gaschromatographische Methode zur simultanen Bestimmung von Mannit und Trehalose in Pilzextrakten beschrieben und damit die Zusammensetzung der Neutralfraktionen einiger Basidiomyceten-species untersucht.

Dora Rast

1965-01-01

437

Entwicklung von Real Time PCR-Methoden zur Bestimmung von Mandel und Haselnuss in Lebensmitteln.  

E-print Network

??Die vorliegende Diplomarbeit beschreibt die Entwicklung, Optimierung und Validierung einer Singleplex Real Time PCR-Methode zur Bestimmung von potentiell allergener Mandel und einer Duplex Real Time… (more)

Leidinger, Caroline

2009-01-01

438

Physiologisch-biochemische und genetische Charakterisierung der Spezies Malassezia pachydermatis unter besonderer Berücksichtigung einer pigmentbildenden Subgruppe.  

E-print Network

??Um Einblicke in Untergruppen der heterogenen Spezies Malassezia pachydermatis zu gewinnen, wurden 205 von einheimischen Tieren stammende Wildisolate, die Referenzstämme CBS 1879 und 1892 und… (more)

Landgraf, Volker Friedrich Wilhelm

2007-01-01

439

Elektronikentwicklung Abbildung 176: Konzeptioneller Entwurf des AHCAL Prototypen (a), und Realisierung der  

E-print Network

- stecker, die die Verbindung zwischen Datenaquisition und der Detektorelektronik realisiert. 286 #12 Verbindung zum inneren Detektor erfolgt ¨uber ultraflache flexible Leiterplatten und Stecker (zu- sammen

440

Schönheit und andere Provokationen - Eine neue evolutionsbiologische Theorie der Kunst  

NASA Astrophysics Data System (ADS)

Die Evolution hat viele spektakuläre Phänomene hervorgebracht - von der Eleganz des Vogelflugs über die gigantischen Körper der Dinosaurier und die farbenprächtige Vielfalt der Korallenriffe bis hin zu ihrem jüngsten Geniestreich - der menschlichen Kunst. Die schönen Künste - Malerei, Bildhauerei und Architektur, Theater, Tanz, Oper und Filmkunst, Musik und Literatur - Produkte der Evolution? Diese Vorstellung mutet vielen Menschen fremd an, aber wie könnte es anders sein? Denn wenn Charles Darwin recht hat, dann sind nicht nur die körperlichen Merkmale der Menschen als Antworten auf die Erfordernisse des Lebens entstanden, sondern auch ihre geistigen Fähigkeiten und Verhaltensweisen. Im Jahr 1859 hatte er auf den letzten Seiten seines berühmten Buches über die Entstehung der Arten eine kühne Prophezeiung gemacht: Durch die Evolutionstheorie werde es "zu einer bemerkenswerten Revolution in der Naturwissenschaft kommen […]. Die Psychologie wird auf die neue Grundlage gestellt, dass jede geistige Kraft und Fähigkeit notwendigerweise durch graduelle Übergänge erworben wird“ (Darwin 1859, S. 484, 488; Junker 2008).

Junker, Thomas

441

Risiko und Resilienz im Leben von Kindern aus multiethnischen Familien  

Microsoft Academic Search

\\u000a Während des größten Teils meines Berufslebens war es mein Privileg, Kinder aus multiethnischen Familien studieren und mit\\u000a ihnen arbeiten zu können, Kinder, die in verschiedenen Gegenden der USA sowie auf verschiedenen Kontinenten in Entwicklungsländern\\u000a aufwuchsen. Die Einsichten, die ich hieraus gewann, stammen von Großstadtkindern im Osten der USA, Einwandererfamilien und\\u000a Flüchtlingen in Kalifornien sowie den Kindern von Kauai. Und nicht

Emmy E. Werner

442

Die hypopeltaten Sepalen von Viola arvensis und Viola mirabilis  

Microsoft Academic Search

Zusammenfassung Die Sepalen vonViola arvensis undViola mirabilis und möglicherweise allerViola-Arten sind, wie die Untersuchungen der äußeren Morphologie, der Ontogenie, der Histogenie und der Bündelmorphologie ergeben, hypopeltat-schildförmige bzw.-schlauchförmige Blätter, deren dorsale Querzone zu dem basalen Anhängsel auswächst. Durch diesen Spreitenbau, der beiViola nur bei den Kelchblättern auftritt, erweisen sich diese als laminale Kelchblätter.

Irmgard Jäger

1963-01-01

443

Kranke, Ströme, Strahlenfelder – Medizin und Elektrizität um 1900  

Microsoft Academic Search

\\u000a Die Beziehungsgeschichte zwischen äußeren Kräften, wundersamen Fluiden oder magnetischen Feldern und der Medizin ist alt.\\u000a Bereits lange vor 1900 hatten beide eine durchaus innige Verbindung konstituiert, die gleichwohl nicht immer frei von Wunderglauben,\\u000a Scharlatanerie und Betrug war. Stellvertretend hierfür mag die Geschichte des Mesmerismus gelten, der zunächst im französischen\\u000a Ancien régime, aber bald auch im revolutionären Frankreich und schließlich in

Wolfgang U. Eckart

444

Ultrasound guided bilateral cervical plexus block reduces postoperative opioid consumption following thyroid surgery.  

PubMed

Thyroid surgery may cause severe postoperative pain and discomfort for patients. Superficial cervical plexus block (SCPB) is one of the regional anesthesia techniques that can provide postoperative analgesia for thyroid surgery. The purpose of this study was to evaluate analgesic effect of ultrasound (US) guided SCPB in patients undergoing thyroid surgery. Fifty ASA I-II patients, aged 20-60, were included in this single blinded study. In a randomized and prospective manner patients were allocated to either SCPB or control group. Bilateral SCPB was performed preoperatively under US guidance using 10 ml 0.25 % bupivacaine for each side. Postoperative analgesia was provided with patient-controlled analgesia method with morphine intravenous. Primary outcome measure was postoperative opioid consumption and analyzed using Mann-Whitney U test. Secondary outcome measures were comparison of opioid side effects like nausea and vomiting and analyzed using Chi square test. VAS scores for pain at postoperative 1st, 6th, 12th, and 24th h were similar in SCPB and control groups (Median VAS values were 2.5, 3, 2, 0 and 3.5, 3, 2, 0 respectively). Postoperative morphine consumption was lower in SCPB group compared to control group at postoperative 6th, 12th, and 24th h (Median doses of morphine consumption were 4, 8, 9 and 5, 9, 11 mg respectively) (P < 0.05). Eight patients in the control group and six patients in the SCBP group had vomiting. Seven patients in the SCPB and none in the control group had hoarseness. Our study has shown that US guided SCPB has a significant analgesic effect in patients undergoing thyroid surgery. Further studies are required to search for the optimal LA dose during US guided SCPB. PMID:25344881

Gürkan, Yavuz; Ta?, Zafer; Toker, Kamil; Solak, Mine

2014-10-26

445

Molekulare Mechanismen zur Absorption von wasserlöslichen Vitaminen und deren Einflussfaktoren.  

E-print Network

??Die intestinale Absorption der wasserlöslichen Vitamine, Biotin, Pantothensäure, Niacin, Thiamin, Pyridoxin, Riboflavin, Ascorbinsäure und Folsäure wird von substratspezifischen Transportmechanismen vermittelt. Es kann gesagt werden, dass… (more)

Stieger, Daniela

2012-01-01

446

Elektrische und spektroskopische Charakterisierung von organischen Feldeffekttransistor-Strukturen.  

E-print Network

??In dieser Arbeit werden die Resultate aus den elektrischen Untersuchungen an organischen Feldeffekttransistoren (OFETs) auf der Basis von Pentacen und von verschiedenen Perylentetracarbonsäurediimid-Derivaten (PTCDI) vorgestellt… (more)

Lehmann, Daniel

2009-01-01

447

Einfluss unterschiedlicher Stickstoffdüngung auf die Aminosäurekonzentration und -zusammensetzung des Phloemsaftes von Tanacetum vulgare (L.) und auf das Such- und Saugverhalten der monophagen Blattlausarten Uroleucon tanaceti (Mordv.) und Macrosiphoniella tanacetaria (Kalt.).  

E-print Network

??Der Einfluss von unterschiedlicher Stickstoffdüngung auf die Aminosäurekonzentration und -zusammensetzung des Phloemsaftes von Tanacetum vulgare L. wurde untersucht sowie Verhaltensbeobachtungen an den Blattlausarten Uroleucon tanaceti… (more)

Nowak, Heike

2008-01-01

448

Zur Ätiologie und Bekämpfung der Lumpy Jaw Disease bei Kängurus.  

E-print Network

??In der vorliegenden Arbeit sollten die in der veterinärmedizinischen Literatur bisher diskutierten Ursachen für LJD bei Makropoden hinsichtlich ihrer tatsächlichen Bedeutung abgeklärt und die Eignung… (more)

Asperger, Michael

2003-01-01

449

Beziehungshaltigkeit und Vernetzungen im Mathematikunterricht der Sekundarstufe I.  

E-print Network

??Die Notwendigkeit einer Untersuchung über Beziehungshaltigkeit und Vernetzungen im Mathematikunterricht ergibt sich einerseits aus den aktuellen bildungspolitischen Forderungen, andererseits aus den reichhaltigen bildungsphilosophischen Traditionen im… (more)

Nordheimer, Swetlana

2014-01-01

450

Best Practice in der Servicesteuerung – ITIL® und ISO 20000  

Microsoft Academic Search

\\u000a Viele Unternehmensorganisationen sind sehr stark mit Informationstechnologie verzahnt. Durch steigende Anforderungen und Erwartungen\\u000a interner und externer Kunden aufgrund neuer Innovationen und Weiterentwicklungen steigt der Bedarf an flexibel reagierenden\\u000a IT Services stetig an. Ohne standardisierte IT-Service-Prozesse wird die Koordination jedoch sehr aufwandig und die Ergebnisse\\u000a werden zufallig. Starke Rahmeninstrumente sind entscheidend dafur, dass der Einsatz der IT-Ressourcen mit den Geschaftszielen\\u000a eines

Horst Grillmayer

451

Verändern pfluglose Bodenbearbeitung und Frühsaaten die Unkrautvegetation im Winterraps?  

Microsoft Academic Search

Zusammenfassung  Im Herbst der Jahre 2005 bis 2007 wurden auf insgesamt 1463 Rapsschlägen in 12 Bundesländern quantitative Untersuchungen zur\\u000a Stärke und Zusammensetzung der Verunkrautung durchgeführt. Ergebnisse zum Einfluss der Bodenbearbeitungsintensität und des\\u000a Saatzeitpunktes auf die Höhe der Gesamtverunkrautung, die Unkrautartenzahl und die Zusammensetzung der Unkrautflora im Raps\\u000a werden dargestellt und Unkrautarten benannt, die sensibel auf die untersuchten Faktoren reagieren.\\u000a \\u000a \\u000a Weder Bodenbearbeitungsintensität

K. Hanzlik; B. Gerowitt

2010-01-01

452

Phänotypische Plastizität und Fitness annueller Ackerwildkrautpopulationen von Standorten unterschiedlicher Nutzungsgeschichte.  

E-print Network

??Die Auswirkungen unterschiedlicher ackerbaulicher Nutzungsgeschichte auf die Fitness von Arabidopsis thaliana- und Viola arvensis-Populationen wurden untersucht. Die dabei verwendeten Versuchspflanzen wurden aus dem bis zu… (more)

Schubert, Patrick

2003-01-01

453

Kommunikation zwischen Arbeiterinnen und Larven der Honigbiene Apis mellifera.  

E-print Network

??In der vorliegenden Arbeit wurde untersucht, ob und woran Arbeiterinnen der Honigbiene (Apis mellifera) den Nahrungsbedarf einzelner Larven erkennen. Als mögliche Signale in diesem Zusammenhang… (more)

Heimken, Christina

2007-01-01

454

Molekulare und immunologische Charakterisierung von Profilin aus Weizen (Triticum aestivum).  

E-print Network

??Krankheiten die nach dem Verzehr von Weizenprodukten bzw. nach der Inhalation von Weizenmehl auftreten sind Zöliakie, Weizenallergie und Bäckerasthma. Eine weitere, jedoch selten auftretende Krankheit,… (more)

Forstenlechner, Peter

2008-01-01

455

Hangexposition und Brutbiologie von Wasseramsel ( Cinclus cinclus ), Trauerschnäpper ( Ficedula hypoleuca ), Kohl und Tannenmeise ( Parus major, P. ater )  

Microsoft Academic Search

Zusammenfassung Im Harz besiedelten 1969–1983 Trauerschnäpper und Wasseramsel Südhänge bevorzugt und erfolgreicher als Nordhänge, Tannenmeisen dagegen Nordhänge. Siedlungsdichte, Höchstvorkommen, Gelegegröße, Zahl der flüggen Jungen pro erfolgreiches Paar, relativer Bruterfolg und Jungenproduktion (bei der Wasseramsel auch die Zahl der Zweitbruten) sind an den Süd-(Nord-) hängen größer als an den Nord-(Süd-)hängen, Legebeginn\\/Schlüpftermin liegen früher (Abb. 8). Zwar sind bei der Kohlmeise Gelegegröße,

Herwig Zang

1985-01-01

456

K\\/Rb, Ca\\/Sr und K\\/Ti-Verhältnisse in basaltoiden Gesteinen der Ostalpen und benachbarter Gebiete  

Microsoft Academic Search

Zusammenfassung Es wurden 69 basaltische Gesteine aus dem ostalpinen und westkarpatischen Orogen sowie aus dem pannonischen Zwischengebirge röntgenfluoreszenzspektrometrisch auf K, Ca, Rb, Sr und Ti analysiert. Eine Auswertung der Korrelationsdiagramme K\\/Rb, Ca\\/Sr und K\\/Ti ergibt für verwandte Gesteine definierte Konzentrationsfelder. Die Alkaliolivinbasalte zeichnen sich, soweit sie nicht durch sekundäre Prozesse Veränderungen erfahren haben, durch relativ enge Konzentrationsfelder aus. Als Mittelwerte

G. Agiorgitis; E. Schroll; Erika Stepán

1970-01-01

457

Leben Und Bildung In Den Klostern Des Fruhen Mittelalters Nach Scheffels "Ekkehard" Und Freytags "Das Nest Der Zaunkonige" Bearbeitet  

E-print Network

Zeit in Mittel^ und Süddeuyschland, zumal in den Klöstern. Wenn einer gar nichts von klösterlichen Einrichtungen und dem klöster^ liehen Leben wüsste, würden ihm diese Werke reiche Kenntnisse darüber gehen. Es befindet sich night viel darin, das... alten Geschichten aus dem Sagenschatze des Hegan erlernt, die so glücklich im Romane angewendet werden. Zur Beschreibung der Klosterschule benutzte er als Vorbild die in der alten Benediktinerabtei Reichenan, die zu seiner Zeit hochgeshätzt wurde und...

Apel, Elizabeth

1915-06-05

458

Is low serum albumin associated with postoperative complications in patients undergoing oesophagectomy for oesophageal malignancies?  

PubMed

A best evidence topic was written according to a structured protocol. The question addressed was: in patients undergoing oesophagectomy for oesophageal malignancy, is low serum albumin associated with postoperative complications? Altogether, 87 papers were found using the reported search, of which 16 demonstrated the best evidence to answer the clinical question. The authors, journal, date and country of publication, patient group studied, study type, relevant outcomes and results of these papers are tabulated. This paper includes 2 level 2 papers, 12 level 3 papers and 2 level 4 papers. All the papers compared either all or some of the following postoperative complications: mortality, morbidity, anastomotic leak, respiratory and non-respiratory complications, and length of hospital stay. Eleven of the 16 papers found an association between low serum albumin and postoperative complications. Of these, one study showed that low serum albumin combined with low fibrinogen levels (FA score) was predictive of postoperative recurrence of oesophageal cancer. Another study showed that when combined with white cell count and C-reactive protein (CRP, NUn score), serum albumin had a high diagnostic accuracy for major complications after postoperative day 3. The largest study compared the in-hospital mortality in 7227 patients who underwent oesophageal surgery for malignancy. The percentage of in-hospital mortality was associated with low serum albumin (<15.0 vs >35.0 g/l, 21.0 vs 11.3%, P <0.001). Five of the 16 papers found no significant association between low serum albumin and postoperative complications. Of these papers, one showed that low serum albumin was not an independent risk factor, while four others found no association between low serum albumin with respiratory complications, anastomotic leak and postoperative mortality. Instead, these studies found other factors responsible for postoperative complications such as: CRP, smoking, disease duration, malnutrition and low T-cell levels. Taken together, while low serum albumin is associated with postoperative complications, opinion regarding the prognostic value of low serum albumin and nutritional support remains conflicted. Because of the confounding factors encountered in these studies, the clinician should consider the finding of low serum albumin in patients, together with disease and surgical factors to provide optimal care for these patients. PMID:25260893

Goh, Sean L; De Silva, Ramesh P; Dhital, Kumud; Gett, Rohan M

2015-01-01

459

Early postoperative complications in patients with Crohn's disease given and not given preoperative total parenteral nutrition  

PubMed Central

Objective The effect of preoperative total parenteral nutrition (TPN) on the rate of early (within 30 days) postoperative complications in patients with moderate to severe Crohn's disease (CD) was examined. Material and methods A series of 15 consecutive patients with CD (mean CD activity index score, 270) given preoperative TPN for 18–90 days (mean, 46 days) and undergoing bowel resection and primary anastomosis was compared with matching controls (105 patients) consecutively selected from all CD patients operated in Stockholm County during a preceding 20-year period without preoperative TPN. Results During the preoperative TPN, all the patients studied displayed clinical remission of CD as reflected in improvement in their general well-being, relief of abdominal pain, and abatement of fever and diarrhea. There was no significant early postoperative complication in the TPN-treated group, whereas there were 29 patients with early postoperative complications in the control group, which means a significantly higher rate of postoperative complications when preoperative TPN was not provided. During the preoperative TPN, some crucial variables increased such as the body weight, the serum concentrations of albumin and triiodothyronine reflecting improved nutritional state, whereas the serum concentration of haptoglobin and the white cell count decreased reflecting decreased inflammatory activity. Conclusions This study shows that preoperative TPN for at least 18 days may be recommended to be given to patients with moderate to severe CD until clinical remission is achieved in order to minimize the risk of early postoperative complications. PMID:22242614

Jacobson, Stefan

2012-01-01

460

A comparison of injection pain and postoperative pain of two intraosseous anesthetic techniques.  

PubMed Central

The purpose of this prospective, randomized, blinded study was to compare injection pain and postoperative pain of an apical primary X-Tip intraosseous technique to a coronal primary Stabident intraosseous technique in mandibular first molars. Using a repeated-measures design, 41 subjects randomly received 2 primary intraosseous injections at 2 separate appointments. Using a site distal to the mandibular first molar for both injections, the subjects received 1.8 mL of 2% lidocaine with 1: 100,000 epinephrine administered with the X-Tip system using an apical location in alveolar mucosa or 1.8 mL of 2% lidocaine with 1: 100,000 epinephrine administered with the Stabident system using a coronal location in attached gingiva. The pain of infiltration, perforation, needle insertion, solution deposition, mock or actual guide sleeve removal and postoperative pain were recorded on a Heft-Parker visual analogue scale (VAS) scale for the 2 intraosseous systems. The results demonstrated that the apical primary X-Tip intraosseous technique was not statistically different (P > .05) from the coronal primary Stabident technique regarding pain ratings of infiltration, perforation, needle insertion, solution deposition, mock or actual guide sleeve removal and postoperative pain (at the time subjective anesthesia wore off). However, on postoperative days 1 through 3, significantly (P < .05) more males experienced postoperative pain with the X-Tip system than with the Stabident system. Images Figure 1 Figure 2 PMID:14558586

Gallatin, Juliane; Nusstein, John; Reader, Al; Beck, Mike; Weaver, Joel

2003-01-01

461

American geriatrics society abstracted clinical practice guideline for postoperative delirium in older adults.  

PubMed

The abstracted set of recommendations presented here provides essential guidance both on the prevention of postoperative delirium in older patients at risk of delirium and on the treatment of older surgical patients with delirium, and is based on the 2014 American Geriatrics Society (AGS) Guideline. The full version of the guideline, American Geriatrics Society Clinical Practice Guideline for Postoperative Delirium in Older Adults is available at the website of the AGS. The overall aims of the study were twofold: first, to present nonpharmacologic and pharmacologic interventions that should be implemented perioperatively for the prevention of postoperative delirium in older adults; and second, to present nonpharmacologic and pharmacologic interventions that should be implemented perioperatively for the treatment of postoperative delirium in older adults. Prevention recommendations focused on primary prevention (i.e., preventing delirium before it occurs) in patients who are at risk for postoperative delirium (e.g., those identified as moderate-to-high risk based on previous risk stratification models such as the National Institute for Health and Care Excellence (NICE) guidelines, Delirium: Diagnosis, Prevention and Management. Clinical Guideline 103; London (UK): 2010 July 29). For management of delirium, the goals of this guideline are to decrease delirium severity and duration, ensure patient safety and improve outcomes. PMID:25495432

2015-01-01

462

Reoperation for early postoperative complications after gastric cancer surgery in a Chinese hospital  

PubMed Central

AIM: To investigate the occurrence of postoperative complications of gastric cancer surgery, and analyze the potential causes of reoperation for early postoperative complications. METHODS: A total of 1639 patients who underwent radical or palliative gastrectomies for gastric cancer were included in the study. The study endpoint was the analysis of postoperative complications in inpatients. RESULTS: About 31% of patients had early postoperative complications, and complications of infection occurred most frequently. Intra-abdominal hemorrhage and anastomotic leak were the main causes of reoperation, which accounted for about 2.2%. Mortality was 11.1% in the reoperation group, but was only 0.8% in other patients. The duration of postoperative stay in hospital was significantly longer and the total expenditure was markedly higher in the patients who underwent reoperation (P < 0.001). There was no significant association of any available factors in this study with the high rate of reoperation. CONCLUSION: Reoperation significantly increases the mortality rate and raises the burden of the surgical unit. More prospective studies are required to explore the potential risk factors. PMID:20039455

Sah, Birendra Kumar; Chen, Ming-Min; Yan, Min; Zhu, Zheng-Gang

2010-01-01

463

Postoperative Pain After Laparoscopic Ventral Hernia Repair: a Prospective Comparison of Sutures Versus Tacks  

PubMed Central

Background and Objectives: Mesh fixation in laparoscopic ventral hernia repair typically involves the use of tacks, transabdominal permanent sutures, or both of these. We compared postoperative pain after repair with either of these 2 methods. Methods: Patients undergoing laparoscopic ventral hernia repair at the Mount Sinai Medical Center were prospectively enrolled in the study. They were sorted into 2 groups (1) those undergoing hernia repairs consisting primarily of transabdominal suture fixation and (2) those undergoing hernia repairs consisting primarily of tack fixation. The patients were not randomized. The technique of surgical repair was based on surgeon preference. A telephone survey was used to follow-up at 1 week, 1 month, and 2 months postoperatively. Results: From 2004 through 2005, 50 patients were enrolled in the study. Twenty-nine had hernia repair primarily with transabdominal sutures, and 21 had repair primarily with tacks. Both groups had similar average age, BMI, hernia defect size, operative time, and postoperative length of stay. Pain scores at 1 week, 1 month, and 2 months were similar. Both groups also had similar times to return to work and need for narcotic pain medication. Conclusions: Patients undergoing laparoscopic ventral hernia repair with primarily transabdominal sutures or tacks experience similar postoperative pain. The choice of either of these fixation methods during surgery should not be based on risk of postoperative pain. PMID:18435881

Nguyen, Scott Q.; Buch, Kerri E.; Schnur, Jessica; Weber, Kaare J.; Katz, L. Brian; Reiner, Mark A.; Aldoroty, Robert A.; Herron, Daniel M.

2008-01-01

464

Evidence-based approach of treatment options for postoperative knee pain.  

PubMed

Optimal pain management is critical after knee surgery to avoid adverse events and to improve surgical outcomes. Pain may affect surgical outcomes by contributing to limitations in range of motion, strength, and functional recovery. The causes of postoperative pain are multifactorial; therefore, an appropriate pain management strategy must take into account preoperative, intraoperative, and postoperative factors to create a comprehensive and individualized plan for the patient. Preoperative assessment includes management of patient expectations, recognition of conditions and early counseling for high-risk patients (ie, opioid dependence, psychiatric comorbidities), and use of preemptive analgesia techniques (ie, preoperative IV medications, peripheral nerve blocks, incisional field blocks). Intraoperative strategies include meticulous surgical technique, limiting the use of tourniquets (ie, duration and pressure), and using preventive analgesia methods (ie, postoperative field block, continuous nerve catheters, intra-articular injection). Postoperative analgesia may be facilitated by cryotherapy, early mobilization, bracing, and rehabilitation. Certain modalities (ie, continuous passive motion devices, transcutaneous electrical nerve stimulation units, iontophoresis) may be important adjuncts in the perioperative period as well. There may be an evolving role for alternative medicine strategies. Early recognition and treatment of exaggerated postoperative pain responses may mitigate the effects of complex regional pain syndrome or the development of chronic pain. PMID:24875973

Farr, Jack; Jaggers, Ryan; Lewis, Hal; Plackis, Andreas; Sim, Seung B; Sherman, Seth L

2014-05-01

465

The implementation of a postoperative care process on a neurosurgical unit.  

PubMed

The postoperative phase is a critical time for any neurosurgical patient. Historically, certain patients having neurosurgical procedures, such as craniotomies and other more complex surgeries, have been nursed postoperatively in the intensive care unit (ICU) for an overnight stay, prior to transfer to a neurosurgical floor. At the Hospital for Sick Children in Toronto, because of challenges with access to ICU beds and the cancellation of surgeries because of lack of available nurses for the ICU setting, this practice was reexamined. A set of criteria was developed to identify which postoperative patients should come directly to the neurosurgical unit immediately following their anesthetic recovery. The criteria were based on patient diagnosis, preoperative condition, comorbidities, the surgical procedure, intraoperative complications, and postoperative status. A detailed process was then outlined that allowed the optimum patients to be selected for this process to ensure patient safety. Included in this process was a postoperative protocol addressing details such as standard physician orders and the levels of monitoring required. Outcomes of this new process include fewer surgical cancellations for patients and families, equally safe, or better patient care, and the conservation of limited ICU resources. The program has currently been expanded to include patients who have undergone endovascular therapies. PMID:16396087

Douglas, Mary; Rowed, Sheila

2005-12-01

466

Effect of sodium hyaluronate on immediate postoperative intraocular pressure after extracapsular cataract extraction and IOL implantation.  

PubMed

We studied 129 eyes which were undergoing extracapsular cataract extraction with IOL-implantation. The amount of residual Healon had a clearcut effect on the IOP elevations postoperatively. In eyes operated on with the intercapsular techniques, pressure elevations and the mean values during the first 6 postoperative hours were significantly higher than in eyes operated on with the planned ECCE (can opener-technique) (P less than 0.01). The pressure elevation reached the maximal values 8-12 h postoperatively and had normalized already at 24 h in most cases, except in glaucomatous eyes which at that time had significantly higher mean IOP values than the non-glaucomatous eyes (P less than 0.01). When operations were done with an air bubble no clearcut postoperative pressure increases could be observed. Our study indicates that a comparatively small amount of Healon may cause a pressure elevation and the amount left in the eye has a greater effect upon the level of the pressure than the duration of the pressure elevation. The less we inject Healon into the eye and the more we avoid leaving it there, the less risk we have of the possibility of vision deteriorating high postoperative intraocular pressure. PMID:2080706

Ruusuvaara, P; Pajari, S; Setälä, K

1990-12-01

467

Outcomes of WHO Grade I Meningiomas Receiving Definitive or Postoperative Radiotherapy  

SciTech Connect

Purpose: We analyzed long-term local control and complications in patients with either pathologically confirmed or clinical World Health Organization Grade I meningiomas treated with definitive or postoperative radiotherapy (RT) at the University of Florida. Methods: Between 1984 and 2006, 146 patients were treated with definitive (n = 88) or postoperative RT after subtotal resection (n = 57) or gross total resection (n = 1). Patients were treated with conventional (n = 41), stereotactic (n = 103), or intensity-modulated RT (n = 2) to a median dose of 52.7 Gy and followed for a median of 7.3 years (range, 0.6-22.0 years) Results: The local control rates at 5 and 10 years were as follows: definitive RT, 99% and 99%; postoperative RT, 96% and 93%; and overall, 97% and 96%, respectively. The 5- and 10-year cause-specific survival rates were as follows: definitive RT 94% and 94%, postoperative RT, 100% and 96%; and overall, 96% and 95%, respectively. The 5- and 10-year overall survival rates were as follows: definitive RT, 81% and 75%; postoperative RT, 96% and 85%; and overall, 87% and 79%, respectively. Severe RT complications occurred in 6.8% of patients; severe surgery-related complications occurred in 10 (17%) of 58 patients treated surgically. Conclusions: The likelihood of cure after definitive RT or following subtotal resection is excellent. However, a small population of patients experience severe complications, even at the moderate dose used for this disease.

Tanzler, Emily; Morris, Christopher G.; Kirwan, Jessica M.; Amdur, Robert J. [Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, Florida (United States); Mendenhall, William M., E-mail: mendwm@shands.ufl.ed [Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, Florida (United States)

2011-02-01

468

Impact of high preoperative steroid doses on postoperative complications among patients on prolonged preoperative steroid therapy.  

PubMed

Corticosteroids are essential to maintain the organic homeostasis. Steroid, glucocorticoid or its synthetic analog is widely used for inflammatory and autoimmune diseases. Prolonged steroid therapy is reported to cause the susceptibility to infection, impaired wound healing and psychoneurosis, however whether the quantity of taking the preoperative steroid is associated the postoperative complication is still unknown. The aim of this study was to elucidate whether the steroid dose in patients on prolonged preoperative steroid therapy is associated postoperative morbidity and mortality. Twenty-five patients taking steroid for various illnesses and underwent the surgery under general anesthesia were selected in this study. The mean +/- standard deviation and the median of the steroid dose converted into hydrocortisone (mg/day) were 39.2 +/- 31.0 and 20, respectively. Of 25 cases, postoperative complications were seen in 10 cases. The postoperative complication was severe based on the grade of Clavien and Dindo by ANOVA as the doses of taking steroid increased (p = 0.0171). The grave postoperative complication classified as Clavien and Dindo grade III occurred with 100% sensitivity and 87% specificity for the steroid dose converted into hydrocortisone > 80 mg/day. Preoperative taking the large amount of steroid (> 80 mg/day) could cause a grave complication. More careful selection of the operative procedure might improve the mobidity rate. PMID:24693677

Iguchi, Tomohiro; Shirabe, Ken; Inoue, Kentaro; Ito, Shuhei; Ohga, Takefumi; Nozoe, Tadahiro; Ezaki, Takahiro; Yoshizumi, Tomoharu; Uchiyama, Hideaki; Soejima, Yuji; Ikegami, Toru; Yamashita, Yo-Ichi; Kawanaka, Hirofumi; Ikeda, Tetsuo; Saeki, Hiroshi; Morita, Masaru; Maehara, Yoshihiko

2013-12-01

469

Second-Look Endoscopy after Gastric Endoscopic Submucosal Dissection for Reducing Delayed Postoperative Bleeding  

PubMed Central

Background/Aims This stuy evaluated the role of a second-look endoscopy after gastric endoscopic submucosal dissection in patients without signs of bleeding. Methods Between March 2011 and March 2012, 407 patients with gastric neoplasms who underwent endoscopic submucosal dissection for 445 lesions were retrospectively reviewed. After the patients had undergone endoscopic submucosal dissection, they were allocated to two groups (with or without second-look endoscopy) according to the following endoscopy. The postoperative bleeding risk of the lesions was not considered when allocating the patients. Results The delayed postoperative bleeding rates did not differ between the two groups (with vs without second-look endoscopy, 3.0% vs 2.1%; p=0.546). However, a tumor in the upper-third of the stomach (odds ratio [OR], 5.353; 95% confidence interval [CI], 1.075 to 26.650) and specimen size greater than 40 mm (OR, 4.794; 95% CI, 1.307 to 17.588) were both independent risk factors for delayed postoperative bleeding. Additionally, second-look endoscopy was not related to reduced delayed postoperative bleeding. However, delayed postoperative bleeding in the patients who did not undergo a second-look endoscopy occurred significantly earlier than that in patients who underwent a second-look endoscopy (4.5 and 14.0 days, respectively, p=0.022). Conclusions A routine second-look endoscopy after gastric endoscopic submucosal dissection is not necessary for all patients. PMID:25170062

Park, Chan Hyuk; Park, Jun Chul; Lee, Hyuk; Shin, Sung Kwan; Lee, Sang Kil; Lee, Yong Chan

2015-01-01

470

Über den Phosphatidgehalt von Kakaopulver und Kakaofett und zur Frage der Bestimmung eines Zusatzes von Lecithin zu Kakaowaren  

Microsoft Academic Search

Zusammenfassung 1.Der Phosphatidgehalt im alkoholischen Auszug von 6 verschiedenen Kakaopulvern ohne Lecithinzusatz lag zwischen 0,389 und 0,980% (berechnet als Lecithin: P2O5×11,32 und bezogen auf die fettfreie Trockensubstanz). Bei 2 präparierten Kakaopulvern betrug der Phosphatidgehalt 0,389 und 0,552%; die Verhältniszahl des alkohollöslichen P2O5 zum Gesamt-P2O5 war 1:63,6 und 1:44,6. Bei den anderen 4 Kakaopulvern, von denen 2 als unpräpariert bezeichnet waren,

K. Braunsdorf

1937-01-01

471

Strategien der Akutintervention durch das pädagogische Fachpersonal einer Behinderteneinrichtung bei aggressivem und destruktivem Verhalten von Kindern und Jugendlichen.  

E-print Network

??Aggressives Verhalten wird in den stationären Erziehungshilfen, dazu zählen auch Wohngruppen mit Kindern und Jugendlichen mit Behinderung, zu einer immer grösser werdenden Problemstellung für die… (more)

Vavra, Claudia

2011-01-01

472

Preoperative depressive symptoms are not predictors of postoperative seizure control in patients with mesial temporal lobe epilepsy and hippocampal sclerosis.  

PubMed

Retrospective data analysis was performed in a sample of 45 consecutive patients who underwent epilepsy surgery for medically refractory mTLE-HS. Beck Depression Inventory (BDI) was used preoperatively to detect actual depressive symptoms and label patients into those "with depressive symptoms" or "without depressive symptoms". Postoperative seizure outcome one, two, and three years after surgery was classified into "complete seizure freedom" versus "presence of auras and/or seizures". Postoperative seizure outcomes were compared in patients with and without depressive symptoms, and no significant difference of postoperative seizure outcome was found. However, there was a non-significant trend for patients with preoperative depressive symptoms to experience a postoperative running down phenomenon more frequently than nondepressed patients. Depressive symptoms, identified by the BDI, do not seem to have a predictive value for postoperative seizure outcome in this highly selected patient population with mTLE-HS, but may be positive predictors for experiencing a postoperative running down phenomenon. PMID:23247268

Lackmayer, Katharina; Lehner-Baumgartner, Eva; Pirker, Susanne; Czech, Thomas; Baumgartner, Christoph

2013-01-01

473

Villafranca Die Kabinete und die Revolutionen.  

E-print Network

Carl heirathen könnte, obschon sie doch wei�, da� er es war, der ihr den Leutnant in der um Rahel oder der Ritter von der feurigen Rose um die schöne Kunijundes von der Blutburg?« »Ich kenn's nich leidet. Aber ich wei� mehr als sie Alle!« »Woher?« Die Frau war etwas verlegen und wandte den Kopf

Prodinger, Helmut

474

Unternehmensplanung und Finanzierbarkeitsnachweis in der Lebensversicherung  

Microsoft Academic Search

4. Schlußfolgerung  Unterstellt man also, daß die für einen Finanzierbarkeitsnachweis maßgebliche Größezumindest einegewisse Stabilität gegenüber Variationen der Rechnungsgrundlagen, der Beobachtungsdauer wie auch der internen Reservierungspolitik aufweisen\\u000a muß — und dies muß nicht nur für einen einzigen Teilbestand, wie wir ihn hier unterstellt haben, gelten —, so ist die freie\\u000a RfB schon aus ganz praktischen Erwägungen hierzu keineswegs geeignet.

Manfred Feilmeier; Georg Reichel

1983-01-01

475

Positionsbestimmung des Unternehmens: Interne und externe Analyse  

Microsoft Academic Search

Die Initiierung und Lenkung von Maßnahmen zur integrierten Modernisierung zielen auf die Verbesserung der Wettbewerbsfähigkeit\\u000a eines Unternehmens ab. Damit diese Maßnahmen zielgerichtet die Wettbewerbsfähigkeit verbessern können, ist Wissen über die\\u000a bestehende Wettbewerbsfähigkeit sowie über die bestehenden Fähigkeiten eine zentrale Voraussetzung. Eine zielgerichtete Auswahl\\u000a problemadäquater Maßnahmen zur Verbesserung der Wettbewerbsfähigkeit bedarf daher im Vorfeld einer Bewertung der aktuellen\\u000a Situation des Unternehmens

Lars Bergmann; Isabel Crespo; Stefan Portmann

2009-01-01

476

Morenos Philosphie und der Pragmatismus (1999)  

Microsoft Academic Search

\\u000a Moreno hat sein Projekt in den USA in einer Phase etabliert, als die Politik durch den „New Deal“ gekennzeichnet war, einer\\u000a optimistischen Reformphase, die Intersubjektivität und Solidarität betonte. In dieser Zeit wird der Pragmatismus begründet,\\u000a ausgehend von Harvard- Gelehrten, die sich 1871-1874 in Cambridge zu einem Diskussionszirkel, dem „Metaphysischen Club“ zusammengeschlossen\\u000a hatten. Dazu gehörten neben Charles Sanders Peirce (1839-1914) (Nagl,

Ferdinand Buer

477

Die Kommunikation des Menschen: Hören und Sprechen  

Microsoft Academic Search

\\u000a Im 2. Lebensjahr von B.K. fällt ihren Eltern auf, dass sie keine Sprache entwickelt. Die Untersuchung beim Arzt zeigt, dass\\u000a keine otoakustischen Emissionen (akustische Ableitung aus dem Innenohr) und keine Hirnstammpotenziale (elektrische Ableitung\\u000a von der Hörbahn des Gehirns) akustisch auslösbar sind. Die weitere Diagnostik ergibt, dass B.K. gehörlos ist. Eine humangenetische\\u000a Untersuchung deckt auf, dass bei B.K. das Gen für

Hans-Peter Zenner

478

Die Kommunikation des Menschen: Hören und Sprechen  

Microsoft Academic Search

Im 2. Lebensjahr von B.K. fällt ihren Eltern auf, dass sie keine Sprache entwickelt. Die Untersuchung beim Arzt zeigt, dass\\u000a keine otoakustischen Emissionen (akustische Ableitung aus dem Innenohr) und keine Hirnstammpotenziale (elektrische Ableitung\\u000a von der Hörbahn des Gehirns) akustisch auslösbar sind. Die weitere Diagnostik ergibt, dass B.K. gehörlos ist. Eine humangenetische\\u000a Untersuchung ergibt, dass bei B.K. das Gen für die

Hans-Peter Zenner

479

Villafranca Die Kabinete und die Revolutionen.  

E-print Network

dabei. Unter der Fahne der Nationalitäten flog der Kampf gegen die alten Throne durch die Länder von den Kampf vom 24. Juni, der Sturm der Rothen gegen die gemä�igten Republikaner, der socialen Clubs gegen die Verpfändung von Arenenberg und meines Grundbesitzes in der Schweiz. Au�erdem werden Sie drei Millionen Francs

Wagner, Stephan

480

Universittsmedizin Gttingen Publikationen und Hochschulschriften 2007  

E-print Network

, Westphal G, Müller M, Hallier E, Brüning T (2007) Strong mutagenic effects of diesel engine emissions using vegetable oil as fuel. ARCH TOXICOL, 81(8): 599-603. 3. Chenot JF, Simmenroth-Nayda A, Koch A, Fischer T) Interdisziplinäres OSCE als alternative Prüfungsform für das Fach Arbeits- und Sozialmedizin. Dokumentation Dt Gesell

Gollisch, Tim

481

Botanische Gärten und die Berliner Flora  

Microsoft Academic Search

Sukopp, H.: Botanische Gärten und die Berliner Flora (Botanic gardens and the flora of Berlin). - Willdenowia 36 (Special Issue): 115-125. - ISSN 0511-9618; © 2006 BGBM Berlin-Dahlem. doi:10.3372\\/wi.36.36108 (available via http:\\/\\/dx.doi.org\\/) In the botanical gardens and arboreta of Berlin many vascular plant taxa have been cultivated since 1573. The influence on the composition of the flora of Berlin by

HERBERT SUKOPP

482

2 Abbildungen und Relationen 4 Graphentheorie I  

E-print Network

) = {a, b, d} (d) = {c} deg(a) = 2 deg(b) = 2 deg(c) = 3 deg(d) = 1 Prof. Dr. Ir Joost-Pieter Katoen (i2 Endknoten der Kante {a, b}. c und {a, c} sind inzident. Prof. Dr. Ir Joost-Pieter Katoen (i2) Vorkurs) ­ (e c b a) (c a b) Prof. Dr. Ir Joost-Pieter Katoen (i2) Vorkurs Informatik 2009 - Diskrete

Ábrahám, Erika

483

Wirkungsunterschiede zwischen Digitalis purpurea und Digitalis lanata  

Microsoft Academic Search

Zusammenfassung Qualitative Unterschiede zwischen Digitalis purpurea und lanata bestehen:1.hinsichtlich der Latenzzeit, die am hypodynamen Straubschen Herzen für Digitalis purpurea 3–4 mal so lang ist, als für Digitalis lanata in gleicher Konzentration.2.wird die maximale Arbeitsleistung (Minutenvolumen) des durchströmten isolierten Froschherzens durch Digitalis lanata rascher erreicht als durch Digitalis purpurea gleicher Konzentration. Die therapeutische Phase dagegen dauert bei dem mit Digitalis purpurea

Fritz Heim

1936-01-01

484

Heinrich Von Kleist Und Die Romantik  

E-print Network

Stimmungsreichen: Es zieht ihn unwiderstehlich zur Romantik. Freilich besass Kleist auch Eigenschaften, die die Romantik garnicht kannte. So haelt sich Kleist von dem Phrasennebel, dem romantisch Verschwommenen fern; der witzige, hoehnische Uebermut der andern... Romantiker war ihm nicht eigen. Die mit dem eigenen Kunstwerk spie- lende Ironie kennt er nicht; er beachtet streng die Ge- setze des Dramas. In knappe Form mit erschuetternder Wucht huellt er nur das Wesentliche ein, und je groesser die Charaktere, je...

Kliewer, Johann Carl

1914-06-01

485

Indivisible und Infinitesimale in der Renaissance  

Microsoft Academic Search

\\u000a Man zählt die Zeit vom beginnenden 15. Jahrhundert bis zum Ende des 16. Jahrhunderts zu der Epoche der Renaissance. Eine genauere\\u000a zeitliche Bestimmung ist schwierig. Die Zeit von etwa 1420 bis 1500 wird mit Frührenaissance bezeichnet. Ganz wesentlich sind\\u000a es die Perspektive in der Malerei und die Bewunderung der bildenden Kunst der Griechen, die das neue Interesse an der Antike

Thomas Sonar

486

Die Exostosis bursata und ihre Entstehung  

Microsoft Academic Search

Privatdocent der miliK4r-medic. Akademie zu St. Petersburg. (Mit 1 Abbildung.) Veto histogenetisehen Standpunkte betraehtet, unterseheidet man, wie bekannt~ zwei Arten yon Exostosen: die sich aus Knorpelgewebe entwickelnden knorpeligen~ und die aus Bindegewebe hervorgehenden~ nieht knorpeligen. Letztere entwickeln sieh entweder aus der Knochenhaut~ oder unabhangig yon derselben. Jeder Theil des Skelets, wenn er nut Knorpelrudimente enthalt, kann als Herd dienen, aus

L. W. Orlow

1890-01-01

487