Sample records for evidensbaserede farmakologiske interventioner

  1. Self-Injurious Behaviour, Non-Interventionism and Practitioners' Needs: Implications for Training and Managerial Support

    ERIC Educational Resources Information Center

    Ntinas, Konstantinos M.

    2014-01-01

    The aim of the present article is to critically analyse the literature concerning the factors that lead to non-interventionism towards self-injurious behaviour (SIB) in the field of intellectual disability and to make recommendations for the development of practice. It emerges that the limited behaviour analytic skills of practitioners impede the…

  2. [Cell signaling pathways interaction in cellular proliferation: Potential target for therapeutic interventionism].

    PubMed

    Valdespino-Gómez, Víctor Manuel; Valdespino-Castillo, Patricia Margarita; Valdespino-Castillo, Víctor Edmundo

    2015-01-01

    Nowadays, cellular physiology is best understood by analysing their interacting molecular components. Proteins are the major components of the cells. Different proteins are organised in the form of functional clusters, pathways or networks. These molecules are ordered in clusters of receptor molecules of extracellular signals, transducers, sensors and biological response effectors. The identification of these intracellular signaling pathways in different cellular types has required a long journey of experimental work. More than 300 intracellular signaling pathways have been identified in human cells. They participate in cell homeostasis processes for structural and functional maintenance. Some of them participate simultaneously or in a nearly-consecutive progression to generate a cellular phenotypic change. In this review, an analysis is performed on the main intracellular signaling pathways that take part in the cellular proliferation process, and the potential use of some components of these pathways as target for therapeutic interventionism are also underlined. Copyright © 2015 Academia Mexicana de Cirugía A.C. Published by Masson Doyma México S.A. All rights reserved.

  3. A solution from hell: the United States and the rise of humanitarian interventionism, 1991-2003.

    PubMed

    Wertheim, Stephen

    2010-01-01

    This article traces the rise of humanitarian interventionist ideas in the US from 1991 to 2003. Until 1997, humanitarian intervention was a relatively limited affair, conceived ad hoc more than systematically, prioritized below multilateralism, aiming to relieve suffering without transforming foreign polities. For this reason, US leaders and citizens scarcely contemplated armed intervention in the Rwandan genocide of 1994: the US 'duty to stop genocide' was a norm still under development. It flourished only in the late 1990s, when humanitarian interventionism, like neoconservatism, became popular in the US establishment and enthusiastic in urging military invasion to remake societies. Now inaction in Rwanda looked outrageous. Stopping the genocide seemed, in retrospect, easily achieved by 5,000 troops, a projection that ignored serious obstacles. On the whole, humanitarian interventionists tended to understate difficulties of halting ethnic conflict, ignore challenges of postconflict reconstruction, discount constraints imposed by public opinion, and override multilateral procedures. These assumptions primed politicians and the public to regard the Iraq war of 2003 as virtuous at best and unworthy of strenuous dissent at worst. The normative commitment to stop mass killing outstripped US or international capabilities—a formula for dashed hopes and dangerous deployments that lives on in the 'responsibility to protect'.

  4. Notes on the Gulf War, Racism, and African-American Social Thought: Ramifications for Teaching.

    ERIC Educational Resources Information Center

    Childs, John Brown

    1991-01-01

    Development and enhancement of multicultural and antiracist educational objectives in classes and educational materials that analyze the connection between racism and militarism are crucial for the development of opposition to U.S. interventionism and war making. African-American community resistance to expressed government explanations of Gulf…

  5. No Retreat: The Failure of Soviet Decision-Making in the Afghan War, 1979-1989

    DTIC Science & Technology

    2013-09-01

    interventionism in the post-colonial world—perhaps a natural expression of improving performance and growing self -confidence—increased tensions with the...rate a quick exit, might have allowed the ever-deepening rift between the Soviet civilian and military leadership to heal , or at least to scab over...and instituting land redistribution and credit reform. To the majority of Afghans this indicated that Kabul was once again in the hands of self

  6. Mathematics in the lower primary years: A research-based perspective on curricula and teaching practice

    NASA Astrophysics Data System (ADS)

    Wright, Bob

    1994-07-01

    Drawing on current research the author explicates twelve assertions relating to curricula, teaching, learners and learning environments in lower primary school mathematics. Topics discussed include: unchanging and under-challenging curricula; the need for greater emphasis on developing children's verbal number strategies and number sense, and on activities specifically suited to prenumerical children; curriculum constraints on teachers; the role of problem solving and differing interpretations of problem solving; the need for a better understanding of how children learn mathematics; differences in children's knowledge; "anti-interventionism," discovery learning, constructivism, children's autonomy and developmental learning; the need for compensatory programs; and learning in collaborative settings. The author concludes that learning and teaching lower primary mathematics continues to be an important area of focus and challenge for teachers and researchers.

  7. ″The Anthropocene″, Ecosystem Management, and Environmental Virtue.

    PubMed

    Sandler, Ronald

    2016-01-01

    *Portions of this article are drawn from: Sandler, R. Environmental Ethics: Theory in Practice, Oxford University Press, New York, in press. In this article I consider contrasting views on the implications of rapid, macroscale anthropogenic change for environmental ethics, particularly ecosystem management, species conservation, and environmental virtue. I begin by reviewing the Anthropocene debate, which has become a primary point of discourse on whether we ought to embrace a more interventionist stance regarding ecosystem management and species conservation. I then discuss the challenges posed by rapid ecological change to predominant ecosystem management and species conservation practices. I argue that these challenges not withstanding, we ought not go all in on interventionist management, even as novel conservation and management techniques can be justified in particular cases. It is possible to adopt a more forward looking normative stance, without licensing robust interventionism. Finally, I discuss the implications of this for some environmental virtues.

  8. Against Explanatory Minimalism in Psychiatry.

    PubMed

    Thornton, Tim

    2015-01-01

    The idea that psychiatry contains, in principle, a series of levels of explanation has been criticized not only as empirically false but also, by Campbell, as unintelligible because it presupposes a discredited pre-Humean view of causation. Campbell's criticism is based on an interventionist-inspired denial that mechanisms and rational connections underpin physical and mental causation, respectively, and hence underpin levels of explanation. These claims echo some superficially similar remarks in Wittgenstein's Zettel. But attention to the context of Wittgenstein's remarks suggests a reason to reject explanatory minimalism in psychiatry and reinstate a Wittgensteinian notion of levels of explanation. Only in a context broader than the one provided by interventionism is that the ascription of propositional attitudes, even in the puzzling case of delusions, justified. Such a view, informed by Wittgenstein, can reconcile the idea that the ascription mental phenomena presupposes a particular level of explanation with the rejection of an a priori claim about its connection to a neurological level of explanation.

  9. The relevance of a rules-based maize marketing policy: an experimental case study of Zambia.

    PubMed

    Abbink, Klaus; Jayne, Thomas S; Moller, Lars C

    2011-01-01

    Strategic interaction between public and private actors is increasingly recognised as an important determinant of agricultural market performance in Africa and elsewhere. Trust and consultation tends to positively affect private activity while uncertainty of government behaviour impedes it. This paper reports on a laboratory experiment based on a stylised model of the Zambian maize market. The experiment facilitates a comparison between discretionary interventionism and a rules-based policy in which the government pre-commits itself to a future course of action. A simple precommitment rule can, in theory, overcome the prevailing strategic dilemma by encouraging private sector participation. Although this result is also borne out in the economic experiment, the improvement in private sector activity is surprisingly small and not statistically significant due to irrationally cautious choices by experimental governments. Encouragingly, a rules-based policy promotes a much more stable market outcome thereby substantially reducing the risk of severe food shortages. These results underscore the importance of predictable and transparent rules for the state's involvement in agricultural markets.

  10. Against Explanatory Minimalism in Psychiatry

    PubMed Central

    Thornton, Tim

    2015-01-01

    The idea that psychiatry contains, in principle, a series of levels of explanation has been criticized not only as empirically false but also, by Campbell, as unintelligible because it presupposes a discredited pre-Humean view of causation. Campbell’s criticism is based on an interventionist-inspired denial that mechanisms and rational connections underpin physical and mental causation, respectively, and hence underpin levels of explanation. These claims echo some superficially similar remarks in Wittgenstein’s Zettel. But attention to the context of Wittgenstein’s remarks suggests a reason to reject explanatory minimalism in psychiatry and reinstate a Wittgensteinian notion of levels of explanation. Only in a context broader than the one provided by interventionism is that the ascription of propositional attitudes, even in the puzzling case of delusions, justified. Such a view, informed by Wittgenstein, can reconcile the idea that the ascription mental phenomena presupposes a particular level of explanation with the rejection of an a priori claim about its connection to a neurological level of explanation. PMID:26696908

  11. Constructing New Expertise: Private and Public Initiatives for Safe Food (Brussels in the First Half of the Nineteenth Century)

    PubMed Central

    Scholliers, Peter

    2014-01-01

    In 1856, the mayor of Brussels proposed the establishment of a municipal laboratory with a chemist to analyse food and beverages to restrain fraud. His proposal was accepted and a laboratory – possibly one of the first municipal laboratories in Europe – was set up. The laboratory still exists today. This paper aims at tracing the conditions in which it emerged, situating it within the laissez-faire context of the time. It was brought into existence by a liberal administration, in a period of little interventionism replete with unencumbered private interests (those of bakers, butchers, grocers, millers, pharmacists, doctors and so on). What will be considered here is the general mood with regard to food fraud, fair trade, correct price, and the quality of food in the first half of the nineteenth century. On a broader level, this contribution addresses the frictions between private and public initiative, while focusing on the process of construction of expertise. The paper makes use of contemporary documents such as reviews, newspapers, association reports and city council chronicles. PMID:25284894

  12. Constructing new expertise: private and public initiatives for safe food (Brussels in the first half of the nineteenth century).

    PubMed

    Scholliers, Peter

    2014-10-01

    In 1856, the mayor of Brussels proposed the establishment of a municipal laboratory with a chemist to analyse food and beverages to restrain fraud. His proposal was accepted and a laboratory - possibly one of the first municipal laboratories in Europe - was set up. The laboratory still exists today. This paper aims at tracing the conditions in which it emerged, situating it within the laissez-faire context of the time. It was brought into existence by a liberal administration, in a period of little interventionism replete with unencumbered private interests (those of bakers, butchers, grocers, millers, pharmacists, doctors and so on). What will be considered here is the general mood with regard to food fraud, fair trade, correct price, and the quality of food in the first half of the nineteenth century. On a broader level, this contribution addresses the frictions between private and public initiative, while focusing on the process of construction of expertise. The paper makes use of contemporary documents such as reviews, newspapers, association reports and city council chronicles.

  13. [Evaluation by focus groups on women's expectations and perceptions during the birth process].

    PubMed

    Ferreiro-Losada, M T; Díaz-Sanisidro, E; Martínez-Romero, M D; Rial-Boubeta, A; Varela-Mallou, J; Clavería-Fontán, A

    2013-01-01

    Delivery care giving is undergoing excessive interventionism today, not supported by scientific evidence, neglecting organisational aspects and individualisation. This study analyses the perception of mothers during their delivery, postpartum and breastfeeding periods in the Galician Health Service, in order to inform and help to improve this service. A total of 14 focus group meetings were held (one in each Galician public hospital), consisting of women who, in 2008, delivered by vaginal delivery or those who were not scheduled for a caesarean section. The process of birth analysis can identify a sequence of important elements both positive and negative, for mothers, and may lead to suggestions for improvement. Their experiences and opinions, especially in aspects such as participation in decision-making, mechanisation of labour and lactation, may help to conduct an assessment of the maternity ward operating. When investigating expectations and demands from users, information from perceived quality is received, and also mothers' experience is shared. Mothers call for humanity, empathy, information and participation. Facing the implementation of these elements, the key processes for working harder are the dilation stage and hospital staying. Copyright © 2012 SECA. Published by Elsevier Espana. All rights reserved.

  14. [Medical and surgical health care for congenital heart disease: a panoramic vision of the reality in Mexico. Inquiry 2009].

    PubMed

    Calderón-Colmenero, Juan; De-la-Llata, Manuel; Vizcaíno, Alfredo; Ramírez, Samuel; Bolio, Alejandro

    2011-01-01

    The only way to characterize the Mexican problem related to congenital heart disease care is promoting the creation of a national database for registering the organization, resources, and related activities. The Health Secretary of Mexico adopted a Spanish registration model to design a survey for obtaining a national Mexican reference in congenital heart disease. This survey was distributed to all directors of medical and/or surgical health care centers for congenital heart disease in Mexico. This communication presents the results obtained in relation to organization, resources and activities performed during the last year 2009. From the 22 health care centers which answered the survey 10 were reference centers (45%) and 12 were assistant centers (55%). All of them are provided with cardiologic auxiliary diagnostic methods. Except one, all centers have at least one bidimentional echocardiography apparatus. There is a general deficit between material and human resources detected in our study. Therapeutic actions for congenital heart disease (70% surgical and 30% therapeutical interventionism) show a clear centralization tendency for this kind of health care in Mexico City, Monterrey and finally Guadalajara. Due to the participation of almost all cardiac health centers in Mexico, our study provides an important information related to organization, resources, and medical and/or surgical activities for congenital heart disease. The data presented not only show Mexican reality, but allows us to identify better the national problematic for establishing priorities and propose solution alternatives.

  15. Effect of changes in technical parameters in radiological safety

    NASA Astrophysics Data System (ADS)

    Avendaño, Ge; Fernandez, C.

    2007-11-01

    This work analyzes the generation of secondary radiation that affects the professionals of health during interventional X ray procedures in first level hospitals. The research objectives were, on the one hand, to quantify the amount of radiation and to compare it with norms in force with respect to magnitudes, and on the other hand to evaluate the elements of protection used. The measurements will help to improve the radiological safety, to assess the eventuality of risks and, in the last term, to the possibility of norms modification for the improvement of the protection, especially that of the personnel who daily make a certain amount of interventional procedures guided by radiation, like angiographic cine applications, using continuous or pulsed fluoroscopy. The motivation of the study is in the suspicion that present interventionism is made with a false sensation of safety, based only in the use of lead apron and protection elements incorporated in the equipment by the manufacturer, nevertheless not always the health personnel are conscious that an excessive proximity with the tube and the patient body becomes a risky source of secondary and scattered radiation. The obtained results allow us to demonstrate the existence of conditions of risk, even possible iatrogenic events, in particular when the procedures imply the use of certain techniques of radiographic exploration, thus reaching the conclusion that the radiographic methodology must be changed in order to rationalize so much?. In order to achieve this we propose modifications to the present norms and legislation referred to the radiological safety in Chile.

  16. Conceptions of politics, morality, and war in the nuclear policy debates

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ware, L.C.

    1993-01-01

    During the resurgent nuclear debates from the mid-1970s to the mid-1980s, analysts sharply disagreed about the appropriate means and ends of strategy. Deterrence dominance strategists argued that America required a countervailing capacity to sustain a viable deterrent posture and to contain Soviet adventurism. Proponents of pure deterrence claimed that the risks endemic to mutual vulnerability would suffice to moderate the superpower rivalry. Advocates of denuclearization charged that reliance on nuclear weaponry posed the greatest danger to human well-being and called for diplomatic measures to establish a disarmament regime. While scholars have systemically explored the strategic and technological components of themore » controversy, few studies have examined the political theoretic dimensions. Through a textual exegesis of the writings of key participants, this work seeks to demonstrate that contending conceptions of politics and morality inform dissension about the viability of coercive power in the nuclear age. Justifications of deterrence dominance proposals generally conflate political and ethical considerations through variants of Hobbesian skepticism or liberal just war interventionism. Such arguments perceive the state as the locus of societal values and sovereignty as sanctioning extensive activities in the global system. Pure deterrence notions posit an irreconcilable tension between politics and morality that corresponds with a tragic vision: war may be a necessary element of sociality, but it seldom has truly creative consequences. From this perspective, the state is a morally ambiguous agent that can preserve and endanger societal well-being. Finally, associated with the denuclearization school is a conviction that progressive social movements can conform politics to essential ethical precepts by minimizing the role of coercive power. In this view, the state and its claim to sovereignty are primary sources of the war system, hence must be radically