Science.gov

Sample records for extensive ageing test

  1. Validity and internal consistency reliability of a computerized test to assess prone extension in children ages four to six years.

    PubMed

    Lin, Chin-Kai; Wu, Huey-Min; Kuo, Bor-Chen; Li, Cheng-Hsaun

    2010-08-01

    The objective of this study was to develop a computerized test of prone extension to measure performance of prone extension in children 4 to 6 years of age. The participants were selected from kindergartens, comprising 132 boys and 107 girls with a mean age of 5 yr. 2 mo. (SD = 6 mo.). Sensitivity and specificity of the computerized test of prone extension were assessed by comparison with the judgments of an expert, an occupational therapist with more than 20 yr. of pediatric experience, as the criterion standard. The computerized test of prone extension identified children with poor outcomes with a sensitivity of 0.83, a specificity of 0.88, and an accuracy of 0.87. The internal reliability index was 0.81. The computerized test of prone extension could be of value in detecting problems of antigravity posture in prone extension and permitting early intervention to correct it. PMID:21058600

  2. A Test and Extension of Objectification Theory as It Predicts Disordered Eating: Does Women's Age Matter?

    ERIC Educational Resources Information Center

    Augustus-Horvath, Casey L.; Tylka, Tracy L.

    2009-01-01

    When predicting disordered eating, models incorporating several of objectification theory's (B. L. Fredrickson & T. A. Roberts, 1997) core constructs (i.e., sexual objectification, self-objectification, body shame, poor interoceptive awareness) have been empirically supported with women of traditional undergraduate age who are consistent in age…

  3. Extensive Air Shower Characteristics as Functions of Shower Age

    NASA Astrophysics Data System (ADS)

    Giller, Maria; Stojek, Hubert; Wieczorek, Grzegorz

    We show that extensive air showers (EAS) are all very similar when described by shower age and Molière length unit. This allows to analyze fluorescence and Cherenkov light emitted by showers in a unified and simple way.

  4. Test Anxiety: Age Appropriate Interventions

    ERIC Educational Resources Information Center

    Ross, David B.; Driscoll, Richard

    2006-01-01

    The presentation covers information on test anxiety reduction strategies from over thirty years of experience with clients of a variety of ages. Dr. Ross is from the College of Lake County. Dr. Driscoll is a private practitioner and Director of the American Test Anxieties Association. The purpose is to address age appropriate test anxiety…

  5. Testing Extension Services through AKAP Models

    ERIC Educational Resources Information Center

    De Rosa, Marcello; Bartoli, Luca; La Rocca, Giuseppe

    2014-01-01

    Purpose: The aim of the paper is to analyse the attitude of Italian farms in gaining access to agricultural extension services (AES). Design/methodology/approach: The ways Italian farms use AES are described through the AKAP (Awareness, Knowledge, Adoption, Product) sequence. This article investigated the AKAP sequence by submitting a…

  6. [Positive skin test and age

    PubMed

    Forte, W C; Júnior, F F; Filho, W D; Shibata, E; Henriques, L S; Mastroti, R A; Guedes, M da S

    2001-01-01

    OBJECTIVE: To evaluate positive responses to skin tests for immediate hypersensitivity to allergens in children with asthma and rhinitis at different ages. METHOD: We observed positive skin test reactivity in prick tests using fifteen allergens of same origin (total dust and Dermatophagoides sp.; Dermatophagoides pteronyssinus; Dermatophagoides farinae; Blomia tropicalis; Penicillium sp; Alternaria alternata; Cladosporium herbarium; Aspergillus fumigatus; Bermuda grass; forage grass; dog and cat epithelia; feathers; Blatella germanica and wool). We placed 713 selected patients into different age groups - Group I: 6 to 11 months; Group II: 1 to 3 years and 11 months; Group III: 4 to 8 years and 11 months; and Group IV: 9 to 15 years. We used the chi-square test for statistical analysis. RESULTS: The total significant differences between these groups were: I to II = 5; II to III = 5; II to IV = 5; III to IV = 6; I to III = 10; and I to IV = 10. CONCLUSION: Skin test reactivity is acquired progressively with age, and can be observed as early as at 12 months. Reactivity is significantly more positive from the age of 4 on. PMID:14647601

  7. OSU Extension, Ohio Aging Network Join Forces: Creating Resources for Successful Aging

    ERIC Educational Resources Information Center

    Goard, Linnette Mizer

    2010-01-01

    Ohio State University Extension and Ohio's Aging Network professionals have worked together for more than a decade to address issues of importance to Ohio's older adult population. The team's mission is to provide education, training, and resources to empower older Ohioans to achieve an optimal level of well-being. The Senior Series team initially…

  8. Monitoring crack extension in fracture toughness tests by ultrasonics

    NASA Technical Reports Server (NTRS)

    Klima, S. J.; Fisher, D. M.; Buzzard, R. J.

    1976-01-01

    An ultrasonic method was used to observe the onset of crack extension and to monitor continued crack growth in fracture toughness specimens during three-point bend tests. A 20-MHz transducer was used with commercially available equipment to detect average crack extension less than 0.09 mm. The material tested was a 300-grade maraging steel in the annealed condition. A crack extension resistance curve was developed to demonstrate the usefulness of the ultrasonic method for minimizing the number of tests required to generate such curves.

  9. Monitoring crack extension in fracture toughness tests by ultrasonics

    NASA Technical Reports Server (NTRS)

    Klima, S. J.; Fisher, D. M.; Buzzard, R. J.

    1975-01-01

    An ultrasonic method was used to observe the onset of crack extension and to monitor continued crack growth in fracture toughness specimens during three point bend tests. A 20 MHz transducer was used with commercially available equipment to detect average crack extension less than 0.09 mm. The material tested was a 300-grade maraging steel in the annealed condition. A crack extension resistance curve was developed to demonstrate the usefulness of the ultrasonic method for minimizing the number of tests required to generate such curves.

  10. GEM: Performance and aging tests

    SciTech Connect

    Cho, H.S.; Kadyk, J.; Han, S.H.; Hong, W.S.; Perez-Mendez, V.; Wenzel, W.; Pitts, K.; Martin, M.D.; Hutchins, J.B.

    1999-06-01

    Performance and aging tests have been done to characterize Gas Electron Multipliers (GEMs), including further design improvements such as a thicker GEM and a closed GEM. Since the effective GEM gain is typically smaller than the absolute GEM gain, due to trapping of avalanche electrons at the bottom GEM electrode, the authors performed field simulations and measurements for better understanding, and discuss methods to eliminate this effect. Other performance parameters of the GEMs are also presented, including absolute GEM gain, short-term and long-term gain stabilities.

  11. Relative Age Effect in Masters Sports: Replication and Extension

    ERIC Educational Resources Information Center

    Medic, Nikola; Starkes, Janet L.; Weir, Patricia L.; Young, Bradley W.; Grove, J. Robert

    2009-01-01

    The relative age effect refers to the performance-related advantage of being born early in a cohort or selection year. Until recently it was unknown whether the relative age effect generalizes across the lifespan. Medic, Starkes, and Young (2007) reasoned that the 5-year age categories that are widely used in masters-level sports to organize…

  12. EMU Ag-Zn battery wet-life extension test

    NASA Technical Reports Server (NTRS)

    Bragg, Bobby J.; Wooten, Claude M.

    1992-01-01

    The Extravehicular Mobility Unit (EMU) silver/zinc (Ag/Zn) battery is an 11 cell battery of approximately 30 AH. The Ag/Zn battery is comprised of two 4-cell monoblocks and one 3-cell monoblock. A discussion of a wet-life extension test performed on the battery is given in viewgraph form.

  13. Informational Theory of Aging: The Life Extension Method Based on the Bone Marrow Transplantation

    PubMed Central

    Karnaukhov, Alexey V.; Karnaukhova, Elena V.; Sergievich, Larisa A.; Karnaukhova, Natalia A.; Bogdanenko, Elena V.; Manokhina, Irina A.; Karnaukhov, Valery N.

    2015-01-01

    The method of lifespan extension that is a practical application of the informational theory of aging is proposed. In this theory, the degradation (error accumulation) of the genetic information in cells is considered a main cause of aging. According to it, our method is based on the transplantation of genetically identical (or similar) stem cells with the lower number of genomic errors to the old recipients. For humans and large mammals, this method can be realized by cryopreservation of their own stem cells, taken in a young age, for the later autologous transplantation in old age. To test this method experimentally, we chose laboratory animals of relatively short lifespan (mouse). Because it is difficult to isolate the required amount of the stem cells (e.g., bone marrow) without significant damage for animals, we used the bone marrow transplantation from sacrificed inbred young donors. It is shown that the lifespan extension of recipients depends on level of their genetic similarity (syngeneity) with donors. We have achieved the lifespan increase of the experimental mice by 34% when the transplantation of the bone marrow with high level of genetic similarity was used. PMID:26491435

  14. THE EXTENSIVE AGE GRADIENT OF THE CARINA DWARF GALAXY

    SciTech Connect

    Battaglia, G.; Irwin, M.; Tolstoy, E.; De Boer, T.; Mateo, M.

    2012-12-20

    The evolution of small systems such as dwarf spheroidal galaxies (dSphs) is likely to have been a balance between external environmental effects and internal processes within their own relatively shallow potential wells. Assessing how strong such environmental interactions may have been is therefore an important element in understanding the baryonic evolution of dSphs and their derived dark matter distribution. Here we present results from a wide-area CTIO/MOSAIC II photometric survey of the Carina dSph, reaching down to about two magnitudes below the oldest main-sequence turnoff (MSTO). This data set enables us to trace the structure of Carina in detail out to very large distances from its center, and as a function of stellar age. We observe the presence of an extended structure made up primarily of ancient MSTO stars, at distances between 25' and 60' from Carina's center, confirming results in the literature that Carina extends well beyond its nominal tidal radius. The large number statistics of our survey reveals features such as isophote twists and tails that were undetected in other previous, shallower surveys. This is the first time that such unambiguous signs of tidal disruption have been found in a Milky Way 'classical' dwarf other than Sagittarius. We also demonstrate the presence of a negative age gradient in Carina directly from its MSTOs, and trace it out to very large distances from the galaxy center. The signs of interaction with the Milky Way make it unclear whether the age gradient was already in place before Carina underwent tidal disruption.

  15. Testing of biomaterials, accelerated ageing.

    PubMed

    Prodinger, A; Krausler, S; Schima, H; Thoma, H; Wolner, E; Schneider, W

    1985-01-01

    The residual elongation is a critical property of materials used for manufacturing diaphragms of artificial hearts. It is therefore important to check goods received or to control manufactured diaphragms, whether their creep properties are within the required limits. Ordinary creep tests take at least several months, while the release of goods received or diaphragms manufactured should be possible within a few days. Acceleration of the creep test by increasing the test temperature permits an estimation whether the creep properties of a material are within the required limits within a week. PMID:3870605

  16. Inspection of two Brayton rotating units after extensive endurance testing

    NASA Technical Reports Server (NTRS)

    Dunn, J. H.

    1976-01-01

    A system was designed to produce 2-10 kW net continuous electric power for at least 5 years. The turbine-alternator-compressor power conversion unit in the system is designated Brayton Rotating Unit (BRU). Four BRU's were fabricated and extensively tested. One BRU has accumulated 11,000 hours of operation, and another has accumulated in excess of 21,000 hours. Testing has demonstrated that the BRU's have met or exceeded performance objectives. Two BRU's were disassembled and given a thorough post-test inspection. The inspection results show that after 21,000 hours of operation there is no apparent wear or failure mode that will prevent the attainment of the 5-year life objective.

  17. An Extensible Open-Source Compiler Infrastructure for Testing

    SciTech Connect

    Quinlan, D; Ur, S; Vuduc, R

    2005-12-09

    Testing forms a critical part of the development process for large-scale software, and there is growing need for automated tools that can read, represent, analyze, and transform the application's source code to help carry out testing tasks. However, the support required to compile applications written in common general purpose languages is generally inaccessible to the testing research community. In this paper, we report on an extensible, open-source compiler infrastructure called ROSE, which is currently in development at Lawrence Livermore National Laboratory. ROSE specifically targets developers who wish to build source-based tools that implement customized analyses and optimizations for large-scale C, C++, and Fortran90 scientific computing applications (on the order of a million lines of code or more). However, much of this infrastructure can also be used to address problems in testing, and ROSE is by design broadly accessible to those without a formal compiler background. This paper details the interactions between testing of applications and the ways in which compiler technology can aid in the understanding of those applications. We emphasize the particular aspects of ROSE, such as support for the general analysis of whole programs, that are particularly well-suited to the testing research community and the scale of the problems that community solves.

  18. FIRST INTERIM STATUS REPORT: MODEL 9975 LIFE EXTENSION PACKAGE TESTING

    SciTech Connect

    Daugherty, W.; Stefek, T.

    2009-12-29

    Three 9975 packages have been instrumented and exposed to bounding storage conditions to help identify the extent to which laboratory test results for fiberboard, O-rings and other components apply within a full-scale package. To date, changes observed in the fiberboard overpack and Oring seals are generally consistent with the behavior of laboratory samples. The lead shield within each package has developed a corrosion layer of lead carbonate, consistent with other 9975 packages. However, the morphology of the corrosion layer is different within these packages, possibly as a result of the severity of the conditioning environments beyond normal service conditions. Conditioning of the second package, LE2, has been discontinued due to the degree of degradation of the fiberboard, and its components have received a final examination. Additional testing will be performed on samples removed from the fiberboard assembly to verify its final condition. The other two packages will continue in test. This is an interim status report for experiments carried out per Task Technical Plan WSRC-TR-2005-00014 [1], which is part of the comprehensive 9975 package surveillance program [2]. The primary goal of this task is to validate aging models currently under development based on lab scale testing of the fiberboard overpack and containment vessel O-rings. A secondary goal is to examine the behavior of the lead shielding under bounding conditions. This task provides an integrated assessment of the package response to environmental extremes, and demonstrates the extent to which data from small samples scale up to a full package. Three 9975 packages have been modified to provide instrumentation for monitoring package response and performance to environmental aging. Each package has a different environmental exposure history.

  19. FIRST INTERIM STATUS REPORT MODEL 9975 LIFE EXTENSION PACKAGE TESTING

    SciTech Connect

    Daugherty, W.; Stefek, T.

    2010-01-27

    Three 9975 packages have been instrumented and exposed to bounding storage conditions to help identify the extent to which laboratory test results for fiberboard, O-rings and other components apply within a full-scale package. To date, changes observed in the fiberboard overpack and O-ring seals are generally consistent with the behavior of laboratory samples. The lead shield within each package has developed a corrosion layer of lead carbonate, consistent with other 9975 packages. However, the morphology of the corrosion layer is different within these packages, possibly as a result of the severity of the conditioning environments beyond normal service conditions. Conditioning of the second package, LE2, has been discontinued due to the degree of degradation of the fiberboard, and its components have received a final examination. Additional testing will be performed on samples removed from the fiberboard assembly to verify its final condition. The other two packages will continue in test. This is an interim status report for experiments carried out per Task Technical Plan WSRC-TR-2005-00014 [1], which is part of the comprehensive 9975 package surveillance program [2]. The primary goal of this task is to validate aging models currently under development based on lab scale testing of the fiberboard overpack and containment vessel O-rings. A secondary goal is to examine the behavior of the lead shielding under bounding conditions. This task provides an integrated assessment of the package response to environmental extremes, and demonstrates the extent to which data from small samples scale up to a full package. Three 9975 packages have been modified to provide instrumentation for monitoring package response and performance to environmental aging. Each package has a different environmental exposure history.

  20. Structural Validity of the Movement ABC-2 Test: Factor Structure Comparisons across Three Age Groups

    ERIC Educational Resources Information Center

    Schulz, Joerg; Henderson, Sheila E.; Sugden, David A.; Barnett, Anna L.

    2011-01-01

    Background: The Movement ABC test is one of the most widely used assessments in the field of Developmental Coordination Disorder (DCD). Improvements to the 2nd edition of the test (M-ABC-2) include an extension of the age range and reduction in the number of age bands as well as revision of tasks. The total test score provides a measure of motor…

  1. Anode wire aging tests with selected gases

    SciTech Connect

    Kadyk, J.; Wise, J.; Hess, D.; Williams, M. )

    1990-04-01

    As a continuation of earlier wire aging investigations, additional candidates for wire chamber gas and wire have been tested. These include the gases: argon/ethane, HRS gas, dimethyl ether, carbon dioxide/ethane, and carbon tetrafluoride/isobutane. Wires used were: gold- plated tungsten, Stablohm, Nicotin, and Stainless Steel. Measurements were made of the effects upon wire aging of impurities from plumbing materials or contamination from various types of oil. Attempts were made to induce wire aging by adding measured amounts of oxygen and halogen (methyl chloride) with negative results. In this paper, the possible role of electronegativity in the wire aging process is discussed, and measurements of electronegativity are made with several single carbon Freons, using both an electron capture detector and a wire chamber operating with dimethyl ether.

  2. The influence of age in usability testing.

    PubMed

    Sonderegger, Andreas; Schmutz, Sven; Sauer, Juergen

    2016-01-01

    The effects of age in usability testing were examined in an experiment. Sixty users from two age groups (M = 23.0 yrs, M = 58.1 yrs) operated two technical devices (keyboard-based and touchscreen-based smartphones). In addition to various performance measures (e.g. task completion time, task completion rate), several subjective measures were taken (e.g. perceived usability, affect, and workload). The results showed better performance scores for younger adults than older adults for task completion time. For older adult users there was a mismatch between usability ratings and task completion time but not between usability ratings and task completion rate. Age-related differences in the importance of speed and accuracy in task completion point to the need to consider more strongly the factor user age in usability research and practice. PMID:26360221

  3. The modified Thomas test is not a valid measure of hip extension unless pelvic tilt is controlled.

    PubMed

    Vigotsky, Andrew D; Lehman, Gregory J; Beardsley, Chris; Contreras, Bret; Chung, Bryan; Feser, Erin H

    2016-01-01

    The modified Thomas test was developed to assess the presence of hip flexion contracture and to measure hip extensibility. Despite its widespread use, to the authors' knowledge, its criterion reference validity has not yet been investigated. The purpose of this study was to assess the criterion reference validity of the modified Thomas test for measuring peak hip extension angle and hip extension deficits, as defined by the hip not being able to extend to 0º, or neutral. Twenty-nine healthy college students (age = 22.00 ± 3.80 years; height = 1.71 ± 0.09 m; body mass = 70.00 ± 15.60 kg) were recruited for this study. Bland-Altman plots revealed poor validity for the modified Thomas test's ability to measure hip extension, which could not be explained by differences in hip flexion ability alone. The modified Thomas test displayed a sensitivity of 31.82% (95% CI [13.86-54.87]) and a specificity of 57.14% (95% CI [18.41-90.10]) for testing hip extension deficits. It appears, however, that by controlling pelvic tilt, much of this variance can be accounted for (r = 0.98). When pelvic tilt is not controlled, the modified Thomas test displays poor criterion reference validity and, as per previous studies, poor reliability. However, when pelvic tilt is controlled, the modified Thomas test appears to be a valid test for evaluating peak hip extension angle. PMID:27602291

  4. The modified Thomas test is not a valid measure of hip extension unless pelvic tilt is controlled

    PubMed Central

    Lehman, Gregory J.; Beardsley, Chris; Contreras, Bret; Chung, Bryan; Feser, Erin H.

    2016-01-01

    The modified Thomas test was developed to assess the presence of hip flexion contracture and to measure hip extensibility. Despite its widespread use, to the authors’ knowledge, its criterion reference validity has not yet been investigated. The purpose of this study was to assess the criterion reference validity of the modified Thomas test for measuring peak hip extension angle and hip extension deficits, as defined by the hip not being able to extend to 0º, or neutral. Twenty-nine healthy college students (age = 22.00 ± 3.80 years; height = 1.71 ± 0.09 m; body mass = 70.00 ± 15.60 kg) were recruited for this study. Bland–Altman plots revealed poor validity for the modified Thomas test’s ability to measure hip extension, which could not be explained by differences in hip flexion ability alone. The modified Thomas test displayed a sensitivity of 31.82% (95% CI [13.86–54.87]) and a specificity of 57.14% (95% CI [18.41–90.10]) for testing hip extension deficits. It appears, however, that by controlling pelvic tilt, much of this variance can be accounted for (r = 0.98). When pelvic tilt is not controlled, the modified Thomas test displays poor criterion reference validity and, as per previous studies, poor reliability. However, when pelvic tilt is controlled, the modified Thomas test appears to be a valid test for evaluating peak hip extension angle. PMID:27602291

  5. Test and Evaluation of Training Extension Course (TEC).

    ERIC Educational Resources Information Center

    Jacobs, T. O.; Hardy, Richard A., Jr.

    The effectiveness of a Training Extension Course (TEC) as a means of increasing the Military Occupational Specialty (MOS) proficiency of Army personnel was evaluated. TEC was implemented by the Combat Arms Training Board using sound/slide as the basic media for 56 lessons. Training material relevant to MOS 11B40, Light Weapons Infantryman, was…

  6. Macroscopic crack formation and extension in pristine and artificially aged PBX 9501

    SciTech Connect

    Liu, Cheng; Thompson, Darla G

    2010-01-01

    A technique has been developed to quantitatively describe macroscopic cracks, both their location and extent, in heterogeneous high explosive and mock materials. By combining such a technique with the deformation field measurement using digital image correlation (DIC), we conduct observation and measurement of the initiation, extension, and coalescence of internal cracks in the compression of Brazilian disk made of pristine and artificially aged PBX 9501 hjgh explosives. Our results conclude quantitatively that aged PBX 9501 is not only weaker but also much more brittle than the pristine one, thus is more susceptible to macroscopic cracking.

  7. Monte Carlo Test Assembly for Item Pool Analysis and Extension

    ERIC Educational Resources Information Center

    Belov, Dmitry I.; Armstrong, Ronald D.

    2005-01-01

    A new test assembly algorithm based on a Monte Carlo random search is presented in this article. A major advantage of the Monte Carlo test assembly over other approaches (integer programming or enumerative heuristics) is that it performs a uniform sampling from the item pool, which provides every feasible item combination (test) with an equal…

  8. Degradation mechanisms and accelerated aging test design

    SciTech Connect

    Clough, R L; Gillen, K T

    1985-01-01

    The fundamental mechanisms underlying the chemical degradation of polymers can change as a function of environmental stress level. When this occurs, it greatly complicates any attempt to use accelerated tests for predicting long-term material degradation behaviors. Understanding how degradation mechanisms can change at different stress levels facilitates both the design and the interpretation of aging tests. Oxidative degradation is a predominant mechanism for many polymers exposed to a variety of different environments in the presence of air, and there are two mechanistic considerations which are widely applicable to material oxidation. One involves a physical process, oxygen diffusion, as a rate-limiting step. This mechanism can predominate at high stress levels. The second is a chemical process, the time-dependent decomposition of peroxide species. This leads to chain branching and can become a rate-controlling factor at lower stress levels involving time-scales applicable to use environments. The authors describe methods for identifying the operation of these mechanisms and illustrate the dramatic influence they can have on the degradation behaviors of a number of polymer types. Several commonly used approaches to accelerated aging tests are discussed in light of the behaviors which result from changes in degradation mechanisms. 9 references, 4 figures.

  9. LEVERAGING AGING MATERIALS DATA TO SUPPORT EXTENSION OF TRANSPORTATION SHIPPING PACKAGES SERVICE LIFE

    SciTech Connect

    Dunn, K.; Bellamy, S.; Daugherty, W.; Sindelar, R.; Skidmore, E.

    2013-08-18

    Nuclear material inventories are increasingly being transferred to interim storage locations where they may reside for extended periods of time. Use of a shipping package to store nuclear materials after the transfer has become more common for a variety of reasons. Shipping packages are robust and have a qualified pedigree for performance in normal operation and accident conditions but are only certified over an approved transportation window. The continued use of shipping packages to contain nuclear material during interim storage will result in reduced overall costs and reduced exposure to workers. However, the shipping package materials of construction must maintain integrity as specified by the safety basis of the storage facility throughout the storage period, which is typically well beyond the certified transportation window. In many ways, the certification processes required for interim storage of nuclear materials in shipping packages is similar to life extension programs required for dry cask storage systems for commercial nuclear fuels. The storage of spent nuclear fuel in dry cask storage systems is federally-regulated, and over 1500 individual dry casks have been in successful service up to 20 years in the US. The uncertainty in final disposition will likely require extended storage of this fuel well beyond initial license periods and perhaps multiple re-licenses may be needed. Thus, both the shipping packages and the dry cask storage systems require materials integrity assessments and assurance of continued satisfactory materials performance over times not considered in the original evaluation processes. Test programs for the shipping packages have been established to obtain aging data on materials of construction to demonstrate continued system integrity. The collective data may be coupled with similar data for the dry cask storage systems and used to support extending the service life of shipping packages in both transportation and storage.

  10. A Flexible, Extensible Online Testing System for Mathematics

    ERIC Educational Resources Information Center

    Passmore, Tim; Brookshaw, Leigh; Butler, Harry

    2011-01-01

    An online testing system developed for entry-skills testing of first-year university students in algebra and calculus is described. The system combines the open-source computer algebra system "Maxima" with computer scripts to parse student answers, which are entered using standard mathematical notation and conventions. The answers can involve…

  11. Test Anxiety: An Extensive Bibliography. TM Report 64.

    ERIC Educational Resources Information Center

    Wildemuth, Barbara M., Comp.

    A large amount of research has been done in the past few decades to pinpoint the effects of test anxiety on the performance of those taking tests. Much of that research is listed in this bibliography, which originated with a computer search of the Educational Resources Information Center (ERIC) data base, Psychological Abstracts, Comprehensive…

  12. Using geodetic VLBI to test Standard-Model Extension

    NASA Astrophysics Data System (ADS)

    Hees, Aurélien; Lambert, Sébastien; Le Poncin-Lafitte, Christophe

    2016-04-01

    The modeling of the relativistic delay in geodetic techniques is primordial to get accurate geodetic products. And geodetic techniques can also be used to measure the relativistic delay and get constraints on parameters describing the relativity theory. The effective field theory framework called the Standard-Model Extension (SME) has been developed in order to systematically parametrize hypothetical violations of Lorentz symmetry (in the Standard Model and in the gravitational sector). In terms of light deflexion by a massive body like the Sun, one can expect a dependence in the elongation angle different from GR. In this communication, we use geodetic VLBI observations of quasars made in the frame of the permanent geodetic VLBI monitoring program to constrain the first SME coefficient. Our results do not show any deviation from GR and they improve current constraints on both GR and SME parameters.

  13. Dark Ages Radio Explorer Instrument Verification Program: Antenna Test Results

    NASA Astrophysics Data System (ADS)

    Datta, Abhirup; Bradley, R.; Burns, J. O.; Lazio, J.; Bauman, J.

    2012-01-01

    Observations of the HI 21 cm transition line promises to be an important probe into the cosmic Dark Ages and Epoch of Reionization. The Dark Ages Radio Explorer (DARE) is designed to measure the sky-averaged 21-cm signal from this cosmic age using a single radiometer operating between 40-120 MHz (redshifts z=11-35). DARE will orbit the Moon for a mission lifetime of ≤ 3 years and take data above the lunar far side, where it is shielded from the Earth's intense interference. The science objectives of DARE include formation of first stars, first accreting black holes, beginning of reionization and end of the Dark Ages. The science instrument is composed of a three-element radiometer, including electrically-short, tapered, bi-conical dipole antennas, a receiver, and a digital spectrometer. Although the TRL (Technology Readiness Level) of the individual components of DARE instrument is high, the overall instrument TRL is low. One of the main aim of the entire DARE team is to advance the instrument TRL. In this work we mainly focus on the development work for DARE Antenna. We will present the initial test results of a prototype DARE antenna, fabricated in NRAO. Some CST simulations using the actual DARE experiment set up have also been performed. In future, we plan to perform extensive tests to characterize the beam pattern and spectral response of the prototype DARE instrument design. In order to utilize the anechoic chamber available at NRAO, we will use a half-scale version of the DARE antenna (120-200 MHz). The full-scale version of the DARE antenna (40-120 MHz) along with the final version of the DARE receiver will be used for outdoor tests in the low-RFI environment of Western Australia. We will also present the initial software development for analyzing the test results from the prototype DARE antenna and receiver.

  14. Aging of concrete components and its significance relative to life extension of nuclear power plants

    SciTech Connect

    Naus, D.J.

    1987-01-01

    Nuclear power currently supplies about 16% of the US electricity requirements, with the percentage expected to rise to 20% by 1990. Despite the increasing role of nuclear power in energy production, cessation of orders for new nuclear plants in combination with expiration of operating licenses for several plants in the next 15 to 20 years results in a potential loss of electrical generating capacity of 50 to 60 gigawatts during the time period 2005 to 2020. A potential timely and cost-effective solution to the problem of meeting future energy demand is available through extension of the service life of existing nuclear plants. Any consideration of plant life extension, however, must consider the concrete components in these plants, since they play a vital safety role. Under the USNRC Nuclear Plant Aging Research (NPAR) Program, a study was conducted to review operating experience and to provide background that will lead to subsequent development of a methodology for assessing and predicting the effects of aging on the performance of concrete-based structures. The approach followed was in conformance with the NPAR strategy.

  15. Innovating aging: promises and pitfalls on the road to life extension

    PubMed Central

    Vijg, Jan; de Grey, Aubrey D.N.J.

    2014-01-01

    One of the main benefits from the dramatic technological progress over the last two centuries is the enormous increase in human life expectancy, which has now reached record highs. After conquering most childhood diseases and a fair fraction of the diseases that plague adulthood, medical technology is now mainly pre-occupied by age-related disorders. Further progress is dependent on circumventing the traditional medical focus on individual diseases and instead targeting aging as a whole as the ultimate cause of the health problems that affect humankind at old age. In principle, a major effort to control the gradual accumulation of molecular and cellular damage – considered by many as the ultimate cause of intrinsic aging – may rapidly lead to interventions for regenerating aged and worn-out tissues and organs. While considered impossible by many, there really is no reason to reject this as scientifically implausible. However, as we discuss, it is not only scientific progress that is currently a limiting factor, but societal factors that hinder and may ultimately prevent further progress in testing and adopting the many possible interventions to cure aging. PMID:24732067

  16. The relation between the lateral profile of giant extensive air showers and the age parameter

    NASA Astrophysics Data System (ADS)

    Capdevielle, Jean-Noël; Cohen, Fabrice

    2005-05-01

    After performing extensive simulations with the code CoRSiKa, we have obtained an analytical description fitting with surprising accuracy the numerical densities up to distances larger than 5 km from the shower axis. This was achieved by using the hypergeometric formalism in place of the traditional NKG approach. The difficulty of cascade theory (validity limited to 3.5 Moliere radii), underlined with reason by the particle data group, is solved here, after overcoming the constraints of approximation B, to show that the distribution of lateral profiles at large distances is also correlated with the age parameter. This is an important step for a coherent interpretation of hybrid events recorded with both surface array and fluorescence telescopes, even with other information coming from Cerenkov or radio emission. A set of hypergeometric Gaussian functions, with a consistent relation between age parameter and total size, is proposed in the ultra-high-energy range (above 1 EeV) for electrons, muons and vertical equivalent muons.

  17. School age test or procedure preparation

    MedlinePlus

    ... type of communication. Older children may benefit from films that show children of the same age explaining, ... procedure. Ask your health care provider if such films are available for your child to watch. Drawing ...

  18. Purpose-in-Life Test: Age and Sex Differences

    ERIC Educational Resources Information Center

    Meier, Augustine; Edwards, Henry

    1974-01-01

    This study examined age and sex differences, and the interaction of age x sex, with respect to "meaning in life" as defined by Frankl and measured by the Purpose-in-Life Test (PIL) developed by Crumbaugh and Maholick. (Author)

  19. Productive extension of semantic memory in school-aged children: Relations with reading comprehension and deployment of cognitive resources.

    PubMed

    Bauer, Patricia J; Blue, Shala N; Xu, Aoxiang; Esposito, Alena G

    2016-07-01

    We investigated 7- to 10-year-old children's productive extension of semantic memory through self-generation of new factual knowledge derived through integration of separate yet related facts learned through instruction or through reading. In Experiment 1, an experimenter read the to-be-integrated facts. Children successfully learned and integrated the information and used it to further extend their semantic knowledge, as evidenced by high levels of correct responses in open-ended and forced-choice testing. In Experiment 2, on half of the trials, the to-be-integrated facts were read by an experimenter (as in Experiment 1) and on half of the trials, children read the facts themselves. Self-generation performance was high in both conditions (experimenter- and self-read); in both conditions, self-generation of new semantic knowledge was related to an independent measure of children's reading comprehension. In Experiment 3, the way children deployed cognitive resources during reading was predictive of their subsequent recall of newly learned information derived through integration. These findings indicate self-generation of new semantic knowledge through integration in school-age children as well as relations between this productive means of extension of semantic memory and cognitive processes engaged during reading. (PsycINFO Database Record PMID:27253263

  20. A test of evolutionary theories of aging

    PubMed Central

    Hughes, Kimberly A.; Alipaz, Julie A.; Drnevich, Jenny M.; Reynolds, Rose M.

    2002-01-01

    Senescence is a nearly universal feature of multicellular organisms, and understanding why it occurs is a long-standing problem in biology. The two leading theories posit that aging is due to (i) pleiotropic genes with beneficial early-life effects but deleterious late-life effects (“antagonistic pleiotropy”) or (ii) mutations with purely deleterious late-life effects (“mutation accumulation”). Previous attempts to distinguish these theories have been inconclusive because of a lack of unambiguous, contrasting predictions. We conducted experiments with Drosophila based on recent population-genetic models that yield contrasting predictions. Genetic variation and inbreeding effects increased dramatically with age, as predicted by the mutation theory. This increase occurs because genes with deleterious effects with a late age of onset are unopposed by natural selection. Our findings provide the strongest support yet for the mutation theory. PMID:12386342

  1. Further Testing of Limits of Cognitive Plasticity: Negative Age Differences in a Mnemonic Skill Are Robust.

    ERIC Educational Resources Information Center

    Baltes, Paul B.; Kliegl, Reinhold

    1992-01-01

    Tested the ability of 19 older adults, given additional training in a mental imagination technique, to approach the performance of 16 younger adults on serial word recall tasks. Results indicated that negative age differences in older adults' performance were substantial, resistant to extensive practice, and applicable to all subjects. (BC)

  2. Pre-Gas Drilling Drinking Water Testing--An Educational Opportunity for Extension

    ERIC Educational Resources Information Center

    Swistock, Brian; Clark, James

    2015-01-01

    The increase in shale gas drilling in Pennsylvania has resulted in thousands of landowners receiving predrilling testing of their drinking water. Landowners often have difficulty understanding test reports resulting in low awareness of pre-existing problems. Extension and several partners developed a program to improve understanding of…

  3. Tests of local Lorentz invariance violation of gravity in the standard model extension with pulsars.

    PubMed

    Shao, Lijing

    2014-03-21

    The standard model extension is an effective field theory introducing all possible Lorentz-violating (LV) operators to the standard model and general relativity (GR). In the pure-gravity sector of minimal standard model extension, nine coefficients describe dominant observable deviations from GR. We systematically implemented 27 tests from 13 pulsar systems to tightly constrain eight linear combinations of these coefficients with extensive Monte Carlo simulations. It constitutes the first detailed and systematic test of the pure-gravity sector of minimal standard model extension with the state-of-the-art pulsar observations. No deviation from GR was detected. The limits of LV coefficients are expressed in the canonical Sun-centered celestial-equatorial frame for the convenience of further studies. They are all improved by significant factors of tens to hundreds with existing ones. As a consequence, Einstein's equivalence principle is verified substantially further by pulsar experiments in terms of local Lorentz invariance in gravity. PMID:24702346

  4. Thermoluminescence dating of sediments: a re-extension of age range for loess

    SciTech Connect

    Johnson, R.J.; Stipp, J.J.; Wintle, A.G.; Tamers, M.A.

    1985-01-01

    Thermoluminescence (TL) dating of wind blown minerals provides a technique whereby non-carbonaceous sediments could be dated to several hundred thousand years. Two recent reports, however, indicate age underestimates on feldspar in some European loesses older than 50 ka, the effect increasing in severity with age. Suggested causes include decay of luminescence centers, or does dependent sensitivity changes. Data presented in this paper do not support these limitations or explanations. TL provides 3 separate techniques of dating sediments, which, when used together, prove to be efficient internal cross checks for mineralogical anomalies or inconsistencies created by any of the individual methods. In the authors studies each sample was dated by all 3 methods whereas the Europeans analyses employed only the Regeneration technique. This work presents results from loess sections in Mississippi, Illinois and Alaska. These show excellent internal consistency, and consistency with both independent dating methods and stratigraphy, with 2 exceptions. Both exceptions were by the Regen technique giving age underestimates up to 30%. The underestimates were found to be caused by a change in mineral sensitivity resulting from the Regen requirements of strong laboratory light-bleaching followed by irradiations. A simple method to test and correct for this condition is presented. TL thus appears to remain a powerful and increasingly flexible method of sediment dating.

  5. Changes in Support Networks in Late Middle Age: The Extension of Gender and Educational Differences

    PubMed Central

    Beresford, Lauren

    2015-01-01

    Objectives. This paper tests whether differences by gender and by educational attainment in contact with friends and family and in support expected from friends and family narrow or widen in late middle age. Methods. The data are drawn from about 4,800 members of the Wisconsin Longitudinal Survey who answered questions about their frequency of contact with social ties and expectations of 3 kinds of help in both 1993, when they were in their early 50s, and again in 2004. Results. Using lagged dependent variable models, we find that between their 50s and 60s women’s network advantages over men and college graduates’ network advantages over high school graduates in frequency of social contact widened. The same was roughly true as well for expectations of social support, although here the divergences depended partly on the type of the support: Women gained relative to men in “talk” support and in help from nonkin if ill, but lost ground in financial support. The college-educated gained ground in all sorts of support from nonkin. Discussion. These results reinforce concern that late middle age is a period when men and the less educated become yet more disadvantaged in social support, making attention to connectedness yet more critical. PMID:24898029

  6. Cybernetic principles of aging and rejuvenation: the buffering- challenging strategy for life extension.

    PubMed

    Heylighen, Francis

    2014-01-01

    Aging is analyzed as the spontaneous loss of adaptivity and increase in fragility that characterizes dynamic systems. Cybernetics defines the general regulatory mechanisms that a system can use to prevent or repair the damage produced by disturbances. According to the law of requisite variety, disturbances can be held in check by maximizing buffering capacity, range of compensatory actions, and knowledge about which action to apply to which disturbance. This suggests a general strategy for rejuvenating the organism by increasing its capabilities of adaptation. Buffering can be optimized by providing sufficient rest together with plenty of nutrients: amino acids, antioxidants, methyl donors, vitamins, minerals, etc. Knowledge and the range of action can be extended by subjecting the organism to an as large as possible variety of challenges. These challenges are ideally brief so as not to deplete resources and produce irreversible damage. However, they should be sufficiently intense and unpredictable to induce an overshoot in the mobilization of resources for damage repair, and to stimulate the organism to build stronger capabilities for tackling future challenges. This allows them to override the trade-offs and limitations that evolution has built into the organism's repair processes in order to conserve potentially scarce resources. Such acute, "hormetic" stressors strengthen the organism in part via the "order from noise" mechanism that destroys dysfunctional structures by subjecting them to strong, random variations. They include heat and cold, physical exertion, exposure, stretching, vibration, fasting, food toxins, micro-organisms, environmental enrichment and psychological challenges. The proposed buffering-challenging strategy may be able to extend life indefinitely, by forcing a periodic rebuilding and extension of capabilities, while using the Internet as an endless source of new knowledge about how to deal with disturbances. PMID:24852018

  7. Testing a New Generation: Implementing Clickers as an Extension Data Collection Tool

    ERIC Educational Resources Information Center

    Parmer, Sondra M.; Parmer, Greg; Struempler, Barb

    2012-01-01

    Using clickers to gauge student understanding in large classrooms is well documented. Less well known is the effectiveness of using clickers with youth for test taking in large-scale Extension programs. This article describes the benefits and challenges of collecting evaluation data using clickers with a third-grade population participating in a…

  8. Effects of Role Demands and Test Cue Properties on Personality Test Performance: Replication and Extension

    ERIC Educational Resources Information Center

    Kroger, Rolf O.; Turnbull, William

    1970-01-01

    In a replication of earlier findings by Kroger, the hypothesis was tested that the situation affects test performance by generating a set of role demands. Community college students described themselves on the SVIB, Taylor Manifest Anxiety Scale, and Welsh Figure Preference Test after being exposed to implicit social cues intended to induce…

  9. Age Sensitivity of Behavioral Tests and Brain Substrates of Normal Aging in Mice

    PubMed Central

    Kennard, John A.; Woodruff-Pak, Diana S.

    2011-01-01

    Knowledge of age sensitivity, the capacity of a behavioral test to reliably detect age-related changes, has utility in the design of experiments to elucidate processes of normal aging. We review the application of these tests in studies of normal aging and compare and contrast the age sensitivity of the Barnes maze, eyeblink classical conditioning, fear conditioning, Morris water maze, and rotorod. These tests have all been implemented to assess normal age-related changes in learning and memory in rodents, which generalize in many cases to age-related changes in learning and memory in all mammals, including humans. Behavioral assessments are a valuable means to measure functional outcomes of neuroscientific studies of aging. Highlighted in this review are the attributes and limitations of these measures in mice in the context of age sensitivity and processes of brain aging. Attributes of these tests include reliability and validity as assessments of learning and memory, well-defined neural substrates, and sensitivity to neural and pharmacological manipulations and disruptions. These tests engage the hippocampus and/or the cerebellum, two structures centrally involved in learning and memory that undergo functional and anatomical changes in normal aging. A test that is less well represented in studies of normal aging, the context pre-exposure facilitation effect (CPFE) in fear conditioning, is described as a method to increase sensitivity of contextual fear conditioning to changes in the hippocampus. Recommendations for increasing the age sensitivity of all measures of normal aging in mice are included, as well as a discussion of the potential of the under-studied CPFE to advance understanding of subtle hippocampus-mediated phenomena. PMID:21647305

  10. Career-Related Variables and Planned Retirement Age: An Extension of Beehr's Model.

    ERIC Educational Resources Information Center

    Adams, Gary A.

    1999-01-01

    A study of 172 older workers found that career commitment and occupational-goal attainment play a central role in planned retirement age. Age and retirement-income satisfaction had the most significant relationship to planned retirement age. Job satisfaction was not strongly related to retirement intentions. (SK)

  11. Aging evaluation of class 1E batteries: Seismic testing

    SciTech Connect

    Edson, J.L. )

    1990-08-01

    This report presents the results of a seismic testing program on naturally aged class 1E batteries obtained from a nuclear plant. The testing program is a Phase 2 activity resulting from a Phase 1 aging evaluation of class 1E batteries in safety systems of nuclear power plants, performed previously as a part of the US Nuclear Regulatory Commission's Nuclear Plant Aging Research Program and reported in NUREG/CR-4457. The primary purpose of the program was to evaluate the seismic ruggedness of naturally aged batteries to determine if aged batteries could have adequate electrical capacity, as determined by tests recommended by IEEE Standards, and yet have inadequate seismic ruggedness to provide needed electrical power during and after a safe shutdown earthquake (SSE) event. A secondary purpose of the program was to evaluate selected advanced surveillance methods to determine if they were likely to be more sensitive to the aging degradation that reduces seismic ruggedness. The program used twelve batteries naturally aged to about 14 years of age in a nuclear facility and tested them at four different seismic levels representative of the levels of possible earthquakes specified for nuclear plants in the United States. Seismic testing of the batteries did not cause any loss of electrical capacity. 19 refs., 29 figs., 7 tabs.

  12. A new test method for young age strength of shotcrete

    SciTech Connect

    Teramoto, Shozo

    1995-12-31

    As a method for testing the young-age strength of shotcrete used as tunnel supports, use of the Parotester, which is designed to measure the hardness of paper rolls at printing factories, has been considered. This paper reports the results of laboratory tests conducted to establish this method as a means of strength testing.

  13. Extensive multiple test centre evaluation of the VecTest malaria antigen panel assay.

    PubMed

    Ryan, J R; Davé, K; Collins, K M; Hochberg, L; Sattabongkot, Jetsumon; Coleman, R E; Dunton, R F; Bangs, M J; Mbogo, C M; Cooper, R D; Schoeler, G B; Rubio-Palis, Y; Magris, M; Romer, L I; Padilla, N; Quakyi, I A; Bigoga, J; Leke, R G; Akinpelu, O; Evans, B; Walsey, M; Patterson, P; Wirtz, R A; Chan, A S T

    2002-09-01

    To determine which species and populations of Anopheles transmit malaria in any given situation, immunological assays for malaria sporozoite antigen can replace traditional microscopical examination of freshly dissected Anopheles. We developed a wicking assay for use with mosquitoes that identifies the presence or absence of specific peptide epitopes of circumsporozoite (CS) protein of Plasmodium falciparum and two strains of Plasmodium vivax (variants 210 and 247). The resulting assay (VecTest Malaria) is a rapid, one-step procedure using a 'dipstick' test strip capable of detecting and distinguishing between P. falciparum and P. vivax infections in mosquitoes. The objective of the present study was to test the efficacy, sensitivity, stability and field-user acceptability of this wicking dipstick assay. In collaboration with 16 test centres world-wide, we evaluated more than 40 000 units of this assay, comparing it to the standard CS ELISA. The 'VecTest Malaria' was found to show 92% sensitivity and 98.1% specificity, with 97.8% accuracy overall. In accelerated storage tests, the dipsticks remained stable for > 15 weeks in dry conditions up to 45 degrees C and in humid conditions up to 37 degrees C. Evidently, this quick and easy dipstick test performs at an acceptable level of reliability and offers practical advantages for field workers needing to make rapid surveys of malaria vectors. PMID:12243234

  14. Age-Related Decrements in Stroop Color Test Performance.

    ERIC Educational Resources Information Center

    Cohn, Nancy B.; And Others

    1984-01-01

    Administered a modified Stroop Color-Word Test to healthy males (N=80) aged 21-90 years as part of a study of neuropsychological functioning. Results showed differences on simple reading tasks; however, significant age effects were observed for the color naming and interference tasks. (LLL)

  15. EFFECT OF ADULT MALLARD AGE ON AVIAN REPRODUCTIVE TESTS

    EPA Science Inventory

    The study was designed to determine the effect of using two different ages of mallard (Anas platyrhynchos) adults within the first breeding season on reproductive tests under standard Toxic Substances Control Act avian reproductive guidelines. The adult age groups were 7 and 11 m...

  16. Aging of composite insulators; Simulation by electrical tests

    SciTech Connect

    de Tourreil, C.H. ); Lambeth, P.J.

    1990-07-01

    To assess the long-term performance of 72 kV and 230 kV composite long rod insulators different laboratory aging tests have been developed. This paper reports two principal diagnostic tests used to measure the performance of the insulators, the quick flashover salt fog (QFO SF), and the rapid flashover clean fog (RFO CF) tests. The aging processes were: cement coating and clean fog, salt fog, and cement coating and salt fog. Similar sets of insulators were aged also in the field for over three years, and all the insulators evaluated in the laboratory. The cement/salt fog aging process was found to be the most controllable and realistic, when the results were assessed by means of the RFO CF test.

  17. Extension of the ACE solar panels is tested in SAEF-II

    NASA Technical Reports Server (NTRS)

    1997-01-01

    Extension of the solar panels is tested on the Advanced Composition Explorer (ACE) spacecraft in KSC's Spacecraft Assembly and Encapsulation Facility-II (SAEF-II). Scheduled for launch on a Delta II rocket from Cape Canaveral Air Station on Aug. 25, ACE will study low-energy particles of solar origin and high-energy galactic particles. The collecting power of instruments aboard ACE is 10 to 1,000 times greater than anything previously flown to collect similar data by NASA.

  18. A service life extension (SLEP) approach to operating aging aircraft beyond their original design lives

    NASA Astrophysics Data System (ADS)

    Pentz, Alan Carter

    With today's uncertain funding climate (including sequestration and continuing budget resolutions), decision makers face severe budgetary challenges to maintain dominance through all aspects of the Department of Defense (DoD). To meet war-fighting capabilities, the DoD continues to extend aircraft programs beyond their design service lives by up to ten years, and occasionally much more. The budget requires a new approach to traditional extension strategies (i.e., reuse, reset, and reclamation) for structural hardware. While extending service life without careful controls can present a safety concern, future operations planning does not consider how much risk is present when operating within sound structural principles. Traditional structural hardware extension methods drive increased costs. Decision makers often overlook the inherent damage tolerance and fatigue capability of structural components and rely on simple time- and flight-based cycle accumulation when determining aircraft retirement lives. This study demonstrates that decision makers should consider risk in addition to the current extension strategies. Through an evaluation of eight military aircraft programs and the application and simulation of F-18 turbine engine usage data, this dissertation shows that insight into actual aircraft mission data, consideration of fatigue capability, and service extension length are key factors to consider. Aircraft structural components, as well as many critical safety components and system designs, have a predefined level of conservatism and inherent damage tolerance. The methods applied in this study would apply to extensions of other critical structures such as bridges. Understanding how much damage tolerance is built into the design compared to the original design usage requirements presents the opportunity to manage systems based on risk. The study presents the sensitivity of these factors and recommends avenues for further research.

  19. Accelerated aging test results for aerospace wire insulation constructions

    NASA Technical Reports Server (NTRS)

    Dunbar, William G.

    1995-01-01

    Several wire insulation constructions were evaluated with and without continuous glow discharges at low pressure and high temperature to determine the aging characteristics of acceptable wire insulation constructions. It was known at the beginning of the test program that insulation aging takes several years when operated at normal ambient temperature and pressure of 20 C and 760 torr. Likewise, it was known that the accelerated aging process decreases insulation life by approximately 50% for each 10 C temperature rise. Therefore, the first phases of the program, not reported in these test results, were to select wire insulation constructions that could operate at high temperature and low pressure for over 10,000 hours with negligible shrinkage and little materials' deterioration.The final phase of the program was to determine accelerated aging characteristics. When an insulation construction is subjected to partial discharges the insulation is locally heated by the bombardment of the discharges, the insulation is also subjected to ozone and other deteriorating gas particles that may significantly increase the aging process. Several insulation systems using either a single material or combinations of teflon, kapton, and glass insulation constructions were tested. All constructions were rated to be partial discharge and/or corona-free at 240 volts, 400 Hz and 260 C (500 F) for 50, 000 hours at altitudes equivalent to the Paschen law. Minimum partial discharge aging tests were preceded by screening tests lasting 20 hours at 260 C. The aging process was accelerated by subjecting the test articles to temperatures up to 370 C (700 F) with and without partial discharges. After one month operation with continuous glow discharges surrounding the test articles, most insulation systems were either destroyed or became brittle, cracked, and unsafe for use. Time with space radiation as with partial discharges is accumulative.

  20. The Effects of Sleep Restriction and Extension on School-Age Children: What a Difference an Hour Makes.

    ERIC Educational Resources Information Center

    Sadeh, Avi; Gruber, Reut; Raviv, Amiram

    2003-01-01

    Assessed effects of sleep restriction and extension on 9- to 12-year-olds' neurobehavioral functioning. Found that modest sleep restriction led to improved sleep quality but to reduced reported alertness. Children who extended sleep improved significantly from baseline their performance on the digit forward memory test and reaction time on the…

  1. Test series 1: seismic-fragility tests of naturally-aged Class 1E Gould NCX-2250 battery cells

    SciTech Connect

    Bonzon, L. L.; Hente, D. B.; Kukreti, B. M.; Schendel, J. S.; Tulk, J. D.; Janis, W. J.; Black, D A; Paulsen, G. D.; Aucoin, B. D.

    1984-09-01

    The seismic-fragility response of naturally-aged, nuclear station, safety-related batteries is of interest for two reasons: (1) to determine actual failure modes and thresholds; and (2) to determine the validity of using the electrical capacity of individual cells as an indicator of the end-of-life of a battery, given a seismic event. This report covers the first test series of an extensive program using 12-year old, lead-calcium, Gould NCX-2250 cells, from the James A. Fitzpatrick Nuclear Power Station operated by the New York Power Authority. Seismic tests with three cell configurations were performed using a triaxial shake table: single-cell tests, rigidly mounted; multi-cell (three) tests, mounted in a typical battery rack; and single-cell tests specifically aimed towards examining propagation of pre-existing case cracks. In general the test philosophy was to monitor the electrical properties including discharge capacity of cells through a graduated series of g-level step increases until either the shake-table limits were reached or until electrical failure of the cells occurred. Of nine electrically active cells, six failed during seismic testing over a range of imposed g-level loads in excess of a 1-g ZPA. Post-test examination revealed a common failure mode, the cracking at the abnormally brittle, positive lead bus-bar/post interface; further examination showed that the failure zone was extremely coarse grained and extensively corroded. Presently accepted accelerated-aging methods for qualifying batteries, per IEEE Std. 535-1979, are based on plate growth, but these naturally-aged 12-year old cells showed no significant plate growth.

  2. Test Series 2: seismic-fragility tests of naturally-aged Class 1E Exide FHC-19 battery cells

    SciTech Connect

    Bonzon, L. L.; Hente, D. B.; Kukreti, B. M.; Schendel, J.; Tulk, J. D.; Janis, W. J.; Black, D. A.; Paulsen, G. D.; Aucoin, B. D.

    1985-03-01

    The seismic-fragility of naturally-aged nuclear station safety-related batteries is of interest for two reasons: (1) to determine actual failure modes and their thresholds and (2) to determine the validity of using the electrical capacity of individual cells as an indicator of the ''end-of-life'' of a battery if subjected to a seismic event. This report, the second in a test series of an extensive seismic research program, covers the testing of 10-year old lead-calcium Exide FHC-19 cells from the Calvert Cliffs Nuclear Power Station operated by the Baltimore Gas and Electric Company. The Exide cells were tested in two configurations using a triaxial shake table: single-cell tests, both rigidly and loosely mounted; and multicell (three-cell) tests, mounted in a typical battery rack. A total of six electrically active cells was used in the two different cell configurations.

  3. Forensic Medicine: Age Written in Teeth by Nuclear Bomb Tests

    SciTech Connect

    Lawrence Livermore National Laboratory

    2005-05-04

    Establishing the age of individuals is an important step in identification and a frequent challenge in forensic medicine. This can be done with high precision up to adolescence by analysis of dentition, but establishing the age of adults has remained difficult. Here we show that measuring {sup 14}C from nuclear bomb tests in tooth enamel provides a sensitive way to establish when a person was born.

  4. Preliminary ageing tests on a superconducting cable dilectric

    SciTech Connect

    Pearmain, A J; Forsyth, E B; Kosaki, M; Thomas, R A

    1980-01-01

    New dielectric tapes were developed for a superconducting, flexible, ac power cable. Preliminary aging tests were performed. Tests show that the proposed system withstood frequency accelerated aging at a cable stress of 10 MV/m for an equivalent 60 Hz time period of te 531 days under the cryogenic conditions of the proposed cable. The partial discharge inception stress for a helium density of 110 kg/m/sup 3/ declined from 12.3 MV/m at the beginning of aging to 7.1 MV/m at the end. This was thought to be due to the erosion of the vapor-deposited aluminum layer on the screen tapes. Although the dielectric tapes were exposed to partial discharge activity for almost the whole period of the test, there was no significant deterioration of the tapes. This suggests that damage due to discharges must be less at cryogenic temperatures.

  5. Aging tests of ethylene contaminated argon/ethane

    SciTech Connect

    Atac, M.; Bauer, G.

    1994-09-22

    We report on aging tests of argon/ethane gas with a minor (1800 ppM) component of ethylene. The measurements were first conducted with the addition of alcohol to test the suppression of aging by this additive, with exposure up to {approx}1.5 C/cm. Tests have included: a proportional tube with ethanol, another with isopropyl alcohol, and for comparison a tube has also been run with ethanol and argon/ethane from CDF`s old (ethylene-free) ethane supply. The aging test with ethanol showed no difference between the ethylene-free and the ethylene tube. Furthermore, raw aging rates of argon/ethane and argon/ethane/ethylene were measured by exposing tubes without the addition of alcohol to about 0.1 C/cm. Again, no significant difference was observed. In conclusion, we see no evidence that ethylene contamination up to 1800 ppM has any adverse effect on wire aging. However, this level of ethylene does seem to significantly suppress the gas gain.

  6. Effect of decontamination on aging processes and considerations for life extension

    SciTech Connect

    Diercks, D.R.

    1987-10-01

    The basis for a recently initiated program on the chemical decontamination of nuclear reactor components and the possible impact of decontamination on extended-life service is described. The incentives for extending plant life beyond the present 40-year limit are discussed, and the possible aging degradation processes that may be accentuated in extended-life service are described. Chemical decontamination processes for nuclear plant primary systems are summarized with respect to their corrosive effects on structural alloys, particularly those in the aged condition. Available experience with chemical cleaning processes for the secondary side of PWR steam generators is also briefly considered. Overall, no severe materials corrosion problems have been found that would preclude the use of these chemical processes, but concerns have been raised in several areas, particularly with respect to corrosion-related problems that may develop during extended service.

  7. Age constraints on late Mesozoic lithospheric extension and origin of bimodal volcanic rocks from the Hailar basin, NE China

    NASA Astrophysics Data System (ADS)

    Li, Shuang-Qing; Hegner, Ernst; Yang, Yi-Zeng; Wu, Jia-De; Chen, Fukun

    2014-03-01

    Following the amalgamation of the late Mesoproterozoic-Carboniferous Central Asian Orogenic Belt with the Siberian and North China cratons, NE China underwent late Mesozoic lithospheric extension and widespread formation of volcano-sedimentary basins. We report U-Pb zircon ages and geochemical data for mafic and felsic volcanic rocks from the Hailar basin, located about 1000 km north of Beijing. Zircon populations of six felsic rock samples analyzed by laser ablation ICP-MS yielded similar U-Pb age spectra ranging from 158 to 125 Ma. The youngest zircon ages are interpreted as time of magma eruption and the xenocrystic zircon-age spectra as evidence for a protracted melting of lower crust due to the underplating of mantle-derived magmas during lithospheric extension. The volcanic assemblage has a bimodal composition comprising geochemically evolved trachybasalts and felsic volcanic rocks of I- and subordinate A-type compositions. The mafic volcanic rocks have negative Nb-anomalies, high Th/Nb and Ce/Pb ratios, low initial ɛNd values of + 0.4 to + 3.4, and radiogenic Pb and Sr isotopes all interpreted as evidence for the melting of passively upwelling asthenosphere and lithospheric mantle previously modified by plate subduction. The xenocrystic zircon ages and chemical/isotopic data of the felsic rocks support an origin from juvenile crustal protoliths: the data of I-type felsic rocks are consistent with the melting of underplated mafic protoliths and those of the A-type rhyolites support the melting of a crustal source with a composition similar to the I-type felsites with apatite controlling their Nb anomaly. The evidence for the persistent melting of a subduction-modified mantle in NE China is in agreement with a model of an extending coupled upper mantle-crust system due to a retreating Paleo-Pacific trench.

  8. Correlating outdoor exposure with accelerated aging tests for aluminum solar reflectors

    NASA Astrophysics Data System (ADS)

    Wette, Johannes; Sutter, Florian; Fernández-García, Aránzazu

    2016-05-01

    Guaranteeing the durability of concentrated solar power (CSP) components is crucial for the success of the technology. The reflectors of the solar field are a key component of CSP plants, requiring reliable methods for service lifetime prediction. So far, no proven correlations exist to relate accelerated aging test results in climate chambers with relevant CSP exposure sites. In this work, correlations have been derived for selected testing conditions that excite the same degradation mechanisms as for outdoor exposure. Those testing conditions have been identified by performing an extensive microscopic comparison of the appearing degradation mechanisms on reference samples that have been weathered outdoors with samples that underwent a high variety of accelerated aging experiments. The herein developed methodology is derived for aluminum reflectors and future work will study its applicability to silvered-glass mirrors.

  9. An Update on Ovarian Aging and Ovarian Reserve Tests

    PubMed Central

    Amanvermez, Ramazan; Tosun, Migraci

    2016-01-01

    Ovaries are the female organs that age more quickly than other tissues such as the uterus, the pituitary gland or pancreas. Different from males, an interesting question is why and how the females lose fertility so rapidly. During the aging process, both the number and quality of the oocytes in the ovaries decrease and reach to a point beyond that no more viable offspring may be produced and the associated cyclic endocrinological activities cease, entering the menopause in females at an average age of 50 years. Females who delayed childbearing with or without their willing until their 30 years or 40 years constitute the largest portion of the total infertility population. Ovarian reserve tests (ORTs) provide an indirect estimate of a female’s diminishing ovarian reserve or remaining follicular pool. This article briefly reviews recent progresses in relation to ovarian aging and ORTs. PMID:26985328

  10. Testing of Large Diameter Fresnel Optics for Space Based Observations of Extensive Air Showers

    NASA Technical Reports Server (NTRS)

    Adams, James H.; Christl, Mark J.; Young, Roy M.

    2011-01-01

    The JEM-EUSO mission will detect extensive air showers produced by extreme energy cosmic rays. It operates from the ISS looking down on Earth's night time atmosphere to detect the nitrogen fluorescence and Cherenkov produce by the charged particles in the EAS. The JEM-EUSO science objectives require a large field of view, sensitivity to energies below 50 EeV, and must fit within available ISS resources. The JEM-EUSO optic module uses three large diameter, thin plastic lenses with Fresnel surfaces to meet the instrument requirements. A bread-board model of the optic has been manufactured and has undergone preliminary tests. We report the results of optical performance tests and evaluate the present capability to manufacture these optical elements.

  11. A modular and extensible data acquisition and control system for testing superconducting magnets

    SciTech Connect

    Darryl F. Orris and Ruben H. Carcagno

    2001-07-20

    The Magnet Test Facility at Fermilab tests a variety of full-scale and model superconducting magnets for both R and D and production. As the design characteristics and test requirements of these magnets vary widely, the magnet test stand must accommodate a wide range of Data Acquisition (DAQ) and Control requirements. Such a system must provide several functions, which includes: quench detection, quench protection, power supply control, quench characterization, and slow DAQ of temperature, mechanical strain gauge, liquid helium level, etc. The system must also provide cryogenic valve control, process instrumentation monitoring, and process interlock logic associated with the test stand. A DAQ and Control system architecture that provides the functionality described above has been designed, fabricated, and put into operation. This system utilizes a modular approach that provides both extensibility and flexibility. As a result, the complexity of the hardware is minimized while remaining optimized for future expansion. The architecture of this new system is presented along with a description of the different technologies applied to each module. Commissioning and operating experience as well as plans for future expansion are discussed.

  12. Aging effects on the structure underlying balance abilities tests.

    PubMed

    Urushihata, Toshiya; Kinugasa, Takashi; Soma, Yuki; Miyoshi, Hirokazu

    2010-01-01

    Balance impairment is one of the biggest risk factors for falls reducing inactivity, resulting in nursing care. Therefore, balance ability is crucial to maintain the activities of independent daily living of older adults. Many tests to assess balance ability have been developed. However, few reports reveal the structure underlying results of balance performance tests comparing young and older adults. Covariance structure analysis is a tool that is used to test statistically whether factorial structure fits data. This study examined aging effects on the factorial structure underlying balance performance tests. Participants comprised 60 healthy young women aged 22 ± 3 years (young group) and 60 community-dwelling older women aged 69 ± 5 years (older group). Six balance tests: postural sway, one-leg standing, functional reach, timed up and go (TUG), gait, and the EquiTest were employed. Exploratory factor analysis revealed that three clearly interpretable factors were extracted in the young group. The first factor had high loadings on the EquiTest, and was interpreted as 'Reactive'. The second factor had high loadings on the postural sway test, and was interpreted as 'Static'. The third factor had high loadings on TUG and gait test, and was interpreted as 'Dynamic'. Similarly, three interpretable factors were extracted in the older group. The first factor had high loadings on the postural sway test and the EquiTest and therefore was interpreted as 'Static and Reactive'. The second factor, which had high loadings on the EquiTest, was interpreted as 'Reactive'. The third factor, which had high loadings on TUG and the gait test, was interpreted as 'Dynamic'. A covariance structure model was applied to the test data: the second-order factor was balance ability, and the first-order factors were static, dynamic and reactive factors which were assumed to be measured based on the six balance tests. Goodness-of-fit index (GFI) of the models were acceptable (young group, GFI

  13. Aging Effects on the Structure Underlying Balance Abilities Tests

    PubMed Central

    Kinugasa, Takashi; Soma, Yuki; Miyoshi, Hirokazu

    2010-01-01

    Balance impairment is one of the biggest risk factors for falls reducing inactivity, resulting in nursing care. Therefore, balance ability is crucial to maintain the activities of independent daily living of older adults. Many tests to assess balance ability have been developed. However, few reports reveal the structure underlying results of balance performance tests comparing young and older adults. Covariance structure analysis is a tool that is used to test statistically whether factorial structure fits data. This study examined aging effects on the factorial structure underlying balance performance tests. Participants comprised 60 healthy young women aged 22 ± 3 years (young group) and 60 community-dwelling older women aged 69 ± 5 years (older group). Six balance tests: postural sway, one-leg standing, functional reach, timed up and go (TUG), gait, and the EquiTest were employed. Exploratory factor analysis revealed that three clearly interpretable factors were extracted in the young group. The first factor had high loadings on the EquiTest, and was interpreted as ‘Reactive’. The second factor had high loadings on the postural sway test, and was interpreted as ‘Static’. The third factor had high loadings on TUG and gait test, and was interpreted as ‘Dynamic’. Similarly, three interpretable factors were extracted in the older group. The first factor had high loadings on the postural sway test and the EquiTest and therefore was interpreted as ‘Static and Reactive’. The second factor, which had high loadings on the EquiTest, was interpreted as ‘Reactive’. The third factor, which had high loadings on TUG and the gait test, was interpreted as ‘Dynamic’. A covariance structure model was applied to the test data: the second-order factor was balance ability, and the first-order factors were static, dynamic and reactive factors which were assumed to be measured based on the six balance tests. Goodness-of-fit index (GFI) of the models were

  14. Testing a model of aging in animal experiments.

    PubMed

    Tyurin YuN; Yakovlev AYu; Shi, J; Bass, L

    1995-03-01

    A stochastic model of aging is developed in terms of accumulation and expression of intracellular lesions caused by environment or intrinsic genetic program. In contrast to the commonly used Gompertz-Makeham approach to the parametric analysis of mortality data, the model yields a hazard function that is bounded from above. For testing the model in experiments aimed at studying animal longevity, a Kolmogorov-type statistical test is presented with regard to the hypothesis involving unknown parameters. Examples concerning longevity of intact animals of two different species, as well as the effect of a prolonged irradiation at a low dose rate, are given to illustrate the model application and goodness-of-fit testing. The results of the analysis of published data show that the rate of lesion formation is not sustained at a constant level throughout life, though in some cases its variations with age can be considered negligible. PMID:7766791

  15. On the Generality of the "Sit and Reach" Test: An Analysis of Flexibility Data for an Aging Population.

    ERIC Educational Resources Information Center

    Shephard, Roy J.; And Others

    1990-01-01

    This study examined head rotation, shoulder extension and rotation, ankle plantar and dorsiflexion, hip flexion, and sit and reach (SR) in 80 adults, aged 45-75, to identify flexibility factors. No single measurement indicates loss of flexibility at all joints, but SR tests are found to be more reliable than others. (SM)

  16. Dynamic testing and analysis of extension-twist-coupled composite tubular spars

    NASA Astrophysics Data System (ADS)

    Lake, Renee C.; Izapanah, Amir P.; Baucon, Robert M.

    The results from a study aimed at improving the dynamic and aerodynamic characteristics of composite rotor blades through the use of extension-twist elastic coupling are presented. A set of extension-twist-coupled composite tubular spars, representative of the primary load carrying structure within a helicopter rotor blade, was manufactured using four plies of woven graphite/epoxy cloth 'prepreg.' These spars were non-circular in cross section design and were therefore subject to warping deformations. Three cross-sectional geometries were developed: square, D-shape, and flattened ellipse. Results from free-free vibration tests of the spars were compared with results from normal modes and frequency analyses of companion shell-finite-element models developed in MSC/NASTRAN. Five global or 'non-shell' modes were identified within the 0-2000 Hz range for each spar. The frequencies and associated mode shapes for the D-shape spar were correlated with analytical results, showing agreement within 13.8 percent. Frequencies corresponding to the five global mode shapes for the square spar agreed within 9.5 percent of the analytical results. Five global modes were similarly identified for the elliptical spar and agreed within 4.9 percent of the respective analytical results.

  17. Dynamic testing and analysis of extension-twist-coupled composite tubular spars

    NASA Technical Reports Server (NTRS)

    Lake, Renee C.; Izapanah, Amir P.; Baucon, Robert M.

    1992-01-01

    The results from a study aimed at improving the dynamic and aerodynamic characteristics of composite rotor blades through the use of extension-twist elastic coupling are presented. A set of extension-twist-coupled composite tubular spars, representative of the primary load carrying structure within a helicopter rotor blade, was manufactured using four plies of woven graphite/epoxy cloth 'prepreg.' These spars were non-circular in cross section design and were therefore subject to warping deformations. Three cross-sectional geometries were developed: square, D-shape, and flattened ellipse. Results from free-free vibration tests of the spars were compared with results from normal modes and frequency analyses of companion shell-finite-element models developed in MSC/NASTRAN. Five global or 'non-shell' modes were identified within the 0-2000 Hz range for each spar. The frequencies and associated mode shapes for the D-shape spar were correlated with analytical results, showing agreement within 13.8 percent. Frequencies corresponding to the five global mode shapes for the square spar agreed within 9.5 percent of the analytical results. Five global modes were similarly identified for the elliptical spar and agreed within 4.9 percent of the respective analytical results.

  18. Collisional tests and an extension of the TEMPEST continuum gyrokinetic code

    NASA Astrophysics Data System (ADS)

    Cohen, R. H.; Dorr, M.; Hittinger, J.; Kerbel, G.; Nevins, W. M.; Rognlien, T.; Xiong, Z.; Xu, X. Q.

    2006-04-01

    An important requirement of a kinetic code for edge plasmas is the ability to accurately treat the effect of colllisions over a broad range of collisionalities. To test the interaction of collisions and parallel streaming, TEMPEST has been compared with published analytic and numerical (Monte Carlo, bounce-averaged Fokker-Planck) results for endloss of particles confined by combined electrostatic and magnetic wells. Good agreement is found over a wide range of collisionality, confining potential and mirror ratio, and the required velocity space resolution is modest. We also describe progress toward extension of (4-dimensional) TEMPEST into a ``kinetic edge transport code'' (a kinetic counterpart of UEDGE). The extension includes averaging of the gyrokinetic equations over fast timescales and approximating the averaged quadratic terms by diffusion terms which respect the boundaries of inaccessable regions in phase space. F. Najmabadi, R.W. Conn and R.H. Cohen, Nucl. Fusion 24, 75 (1984); T.D. Rognlien and T.A. Cutler, Nucl. Fusion 20, 1003 (1980).

  19. Design, development, and hover testing of a helicopter rotor blade chord extension morphing system

    NASA Astrophysics Data System (ADS)

    Gandhi, Farhan; Hayden, Eric

    2015-03-01

    A rotor blade chord extension system was designed, fabricated and hover tested, using electromechanical and pneumatic actuation. A 1.5 in actuator stroke output in the spanwise direction was converted into chordwise motion of a trailing-edge plate (TEP), via a rigid link. On the hover stand, with a 20 V dc input, the electromechanical actuator was shown to fully extend and retract the plate at rotational speeds up to 385 RPM (which put the system at a centrifugal loading of 209.5 g, or 47.2% of that on a Black Hawk helicopter at 73% span). The configuration was changed to reduce the actuator force requirement for the pneumatic actuator. The rotor test facility allowed a maximum of 105 psi pressure input through the rotary union (significantly lower than the rating of the actuator). At these moderate pressure inputs, full TEP deployment was observed at 315 RPM (140.2 g, or 31.6% of that on a Black Hawk helicopter at 73% span). The model prediction of TEP displacement versus pressure showed good correlation with test results.

  20. CPV solar receiver ageing tests: The enhanced electroluminescence method

    NASA Astrophysics Data System (ADS)

    Mabille, Loïc; Mangeant, Christophe; Baudrit, Mathieu

    2013-09-01

    For two years now, CEA INES is involved in the development of insulated metal substrates (IMS) for CPV receivers. In an effort for establishing the reliability of such a new design compared to state-of-the-art direct bonded copper (DBC) design, accelerated ageing test have been carried out. During these tests, several characterization tools were used including current voltage measurements, X-ray tomography and electroluminescence. A new method for the characterization of thermal inhomogeneities has been developed, the so-called Enhanced Electroluminescence (EEL) which is described in this paper.

  1. Accelerated aging tests of liners for uranium mill tailings disposal

    SciTech Connect

    Barnes, S.M.; Buelt, J.L.; Hale, V.Q.

    1981-11-01

    This document describes the results of accelerated aging tests to determine the long-term effectiveness of selected impoundment liner materials in a uranium mill tailings environment. The study was sponsored by the US Department of Energy under the Uranium Mill Tailings Remedial Action Project. The study was designed to evaluate the need for, and the performance of, several candidate liners for isolating mill tailings leachate in conformance with proposed Environmental Protection Agency and Nuclear Regulatory Commission requirements. The liners were subjected to conditions known to accelerate the degradation mechanisms of the various liners. Also, a test environment was maintained that modeled the expected conditions at a mill tailings impoundment, including ground subsidence and the weight loading of tailings on the liners. A comparison of installation costs was also performed for the candidate liners. The laboratory testing and cost information prompted the selection of a catalytic airblown asphalt membrane and a sodium bentonite-amended soil for fiscal year 1981 field testing.

  2. Ageing tests and recovery procedures of silica aerogel

    NASA Astrophysics Data System (ADS)

    Perego, D. L.

    2008-09-01

    Silica aerogel has been extensively used in RICH detectors for the identification of charged particles over the momentum range between 1 and 10 GeV/c. Tiles of hygroscopic aerogel with large transverse dimensions (20×20 cm2) and refractive index n=1.03 have recently been produced for use in the LHCb experiment, allowing pion-kaon identification up to 10 GeV/c. The tiles have excellent optical properties (clarity factor better than 0.006 μm4/cm and homogeneity σ(n-1)/(n-1)˜1% within the tile). Extensive R&D tests on aerogel samples have been performed. Samples have been exposed to intense irradiation (proton, neutron and gamma), to humid air, to standard black varnish (used to paint the inner surface of RICH detectors), and to C 4F 10 and CO 2 gases. The optical properties of the aerogel have been monitored during these tests and, when required, recovery procedures have been investigated and applied. In particular, regeneration of the tiles has been realized through exposure to dry atmosphere (gaseous N 2) or through baking for several hours at 500C. The measurements demonstrate that the optical properties have been successfully restored to their values at the production stage, and in no case permanent degradation has been observed.

  3. Effects of Reference Performance Testing During Aging Using Commercial Cells

    SciTech Connect

    Jon P. Christophersen; Chinh D. Ho; David Howell

    2005-07-01

    The Advanced Technology Development Program, under the oversight of the U.S. Department of Energy’s FreedomCAR and Vehicle Technologies Program, is investigating lithium-ion batteries for hybrid-electric vehicle applications. Cells are aged under various test conditions, including temperatures and states-of-charge. Life testing is interrupted at regular intervals to conduct reference performance tests (RPTs), which are used to measure changes in the electrical performance of the cells and then to determine cell degradation as a function of test time. Although designed to be unobtrusive, data from the Advanced Technology Development Gen 2 cells indicated that RPTs actually contributed to cell degradation and failure. A study was performed at the Idaho National Laboratory using commercially available lithium-ion cells to determine the impact of RPTs on life. A series of partial RPTs were performed at regular intervals during life testing and compared to a control group that was life tested without RPT interruption. It was determined that certain components of the RPT were detrimental, while others appeared to improve cell performance. Consequently, a new "mini" RPT was designed as an unobtrusive alternative. Initial testing with commercial cells indicates that the impact of the mini RPT is significantly less than the Gen 2 cell RPT.

  4. Minnesota Retrofit Insulation In-Situ Test Program: extension and review

    SciTech Connect

    Not Available

    1980-02-01

    An insulation's performance is of primary concern to the consumer who is considering re-insulating his home. Minnesota Retrofit Insulation In Situ Test Program, published by the Department of Energy in June 1978, details the findings of an in situ study of various thermal insulations installed in 55 residences in the Minneapolis/St. Paul area. The study, conducted in the summer of 1977, consisted of field observations and laboratory measurements of properties critical to the insulations' performance. Properties studied included density, thermal resistance, moisture content, shrinkage, flammability, friability, and compression strength. This study, Phase I, was extended with a second phase to include further in-situ study of retrofit insulations. Included in this extension work, Phase II, was a further study of the moisture content of insulations, the corrosiveness of retrofit loose-fill cellulose insulation, thermography and field observations of sidewalls for signs of settling of retrofit loose-fill insulations, analysis of fuel consumption data for a number of the retrofitted homes, and density and thermal resistance retests of loose-fill insulations. This report details the field and laboratory findings of Phase II.

  5. 75 FR 28231 - Cotton Classing, Testing and Standards: Notice of Request for an Extension and Revision to a...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-20

    ... Agricultural Marketing Service Cotton Classing, Testing and Standards: Notice of Request for an Extension and... approved information collection Cotton Classing, Testing, and Standards. DATES: Comments received by July... submit written comments concerning this proposal to Shethir Riva, Chief, Research and Promotion,...

  6. Fabrication and Testing of Low Cost 2D Carbon-Carbon Nozzle Extensions at NASA/MSFC

    NASA Technical Reports Server (NTRS)

    Greene, Sandra Elam; Shigley, John K.; George, Russ; Roberts, Robert

    2015-01-01

    Subscale liquid engine tests were conducted at NASA/MSFC using a 1.2 Klbf engine with liquid oxygen (LOX) and gaseous hydrogen. Testing was performed for main-stage durations ranging from 10 to 160 seconds at a chamber pressure of 550 psia and a mixture ratio of 5.7. Operating the engine in this manner demonstrated a new and affordable test capability for evaluating subscale nozzles by exposing them to long duration tests. A series of 2D C-C nozzle extensions were manufactured, oxidation protection applied and then tested on a liquid engine test facility at NASA/MSFC. The C-C nozzle extensions had oxidation protection applied using three very distinct methods with a wide range of costs and process times: SiC via Polymer Impregnation & Pyrolysis (PIP), Air Plasma Spray (APS) and Melt Infiltration. The tested extensions were about 6" long with an exit plane ID of about 6.6". The test results, material properties and performance of the 2D C-C extensions and attachment features will be discussed.

  7. An extension of the Wilcoxon-Mann-Whitney test for analyzing RT-qPCR data.

    PubMed

    De Neve, Jan; Thas, Olivier; Ottoy, Jean-Pierre; Clement, Lieven

    2013-06-01

    Classical approaches for analyzing reverse transcription quantitative polymerase chain reaction (RT-qPCR) data commonly require normalization before assessing differential expression (DE). Normalization often has a substantial effect on the interpretation and validity of the subsequent analysis steps, but at the same time it causes a reduction in variance and introduces dependence among the normalized outcomes. These effects can be substantial, however, they are typically ignored. Most normalization techniques and methods for DE focus on mean expression and are sensitive to outliers. Moreover, in cancer studies, for example, oncogenes are often only expressed in a subsample of the populations during sampling. This primarily affects the skewness and the tails of the distribution and the mean is therefore not necessarily the best effect size measure within these experimental setups. In our contribution, we propose an extension of the Wilcoxon-Mann-Whitney test which incorporates a robust normalization, and the uncertainty associated with normalization is propagated into the final statistical summaries for DE. Our method relies on semiparametric regression models that focus on the probability P{Y ≤ Y'}, where Y and Y' denote independent responses for different subject groups. This effect size is robust to outliers, while remaining informative and intuitive when DE affects the shape of the distribution instead of only the mean. We also extend our approach for assessing DE for multiple features simultaneously. Simulation studies show that the test has a good performance, and that it is very competitive with standard methods for this platform. The method is illustrated on two neuroblastoma studies. PMID:23652635

  8. Extension and application of the "enzyme test bench" for oxygen consuming enzyme reactions.

    PubMed

    Rachinskiy, Kirill; Kunze, Martin; Graf, Careen; Schultze, Hergen; Boy, Matthias; Büchs, Jochen

    2014-02-01

    Within industrial process development, powerful screening techniques are required to select the optimal biocatalyst regarding such process characteristics as cost effectiveness, turnover number or space time yield. Conventional measurement of the initial enzyme activity, which is the established high throughput screening technique, disregards the long-term stability of an enzyme. A new model based technique called "enzyme test bench" was recently presented before by our group which addresses this issue. It combines the high throughput screening approach with an extensive enzyme characterization, focusing especially on the long-term stability. The technique is based on modeling enzyme activation and deactivation as temperature dependent reactions in accordance with the Arrhenius law. Controlling these reactions by tailor made temperature profiles, the slow long-term deactivation effects are accelerated and characterizing models are parameterized. Thus, the process properties of an enzyme can be predicted and included into the screening procedure. Moreover, the optimum process temperature as function of the envisaged operation time can be found by these means. In this work, the technique is extended to the important class of oxygen consuming reactions. For this aim, a suitable assay and a defined oxygen supply were established. This extended technique was applied to characterize and to optimize a complex, multi-stage laccase-mediator system (LMS). For the variation and optimization of the enzyme to mediator to substrate ratio, experiments in microtiter plates were performed. Predictions from this high throughput characterization were compared to long-term experiments in a RAMOS device (Respiration Activity Monitoring System), a technique for on-line monitoring of the oxygen transfer rate in shake flasks. Within the limits of the model validity, the enzyme test bench predictions are in good agreement with the long-term experiments. PMID:23928872

  9. Reliability and Validity of Standing Back Extension Test for Detecting Motor Control Impairment in Subjects with Low Back Pain

    PubMed Central

    Kumar, Senthil P; Eapen, Charu; Mahale, Ajit

    2016-01-01

    Introduction Low back pain is a chronic health problem with high socioeconomic impact. Specific diagnosis or treatment approach has not yet effectively established to treat chronic low back pain. Standing Back Extension Test is one of the clinical measures to detect the passive extension subgroup of Motor Control Impairment (MCI); which could have an impact on spinal stability leading to recurrent chronic low back pain. Reliability and validity of this test is not fully established. Aim To determine the intra-rater and inter-rater reliability and concurrent validity of the Standing Back Extension Test for detecting MCI of the lumbar spine. Materials and Methods A total of 50 subjects were included in the study, 25 patients with Non Specific Low Back Pain (NSLBP) (12 men, 13 women) and 25 healthy controls (12 men, 13 women) were recruited into the study. All subjects performed the test movement. Two raters blinded to the subjects rated the test performance as either ‘Positive’ or ‘Negative’ based on the predetermined rating protocol. The thickness of Transverse Abdominis (TrA) muscle was assessed using Rehabilitative Ultrasound Imaging (RUSI). Statistical test used For reliability, the kappa coefficient with percent agreement was calculated and for assessing the validity Receiver Operator Characteristic (ROC) curves and Area under the Curve (AUC) were constructed. Results The standing back extension test showed very good intra-rater (k=0.87 with an agreement of 96%) and good inter-rater (k=0.78 with an agreement of 94%) reliability and high AUC for TrA muscle. Conclusion The standing back extension test was found to be a reliable and a valid measure to detect passive extension subgroup for MCI in subjects with low back pain. PMID:26894091

  10. Is procrastination a vulnerability factor for hypertension and cardiovascular disease? Testing an extension of the procrastination-health model.

    PubMed

    Sirois, Fuschia M

    2015-06-01

    Personality is an important epidemiological factor for understanding health outcomes. This study investigated the associations of trait procrastination with hypertension and cardiovascular disease (HT/CVD) and maladaptive coping by testing an extension of the procrastination-health model among individuals with and without HT/CVD. Individuals with self-reported HT/CVD (N = 182) and healthy controls (N = 564), from a community sample, completed an online survey including measures of personality, coping, and health outcomes. Logistic regression analysis controlling for demographic and higher order personality factors found that older age, lower education level and higher procrastination scores were associated with HT/CVD. Moderated mediation analyses with bootstrapping revealed that procrastination was more strongly associated with maladaptive coping behaviours in participants with HT/CVD than the healthy controls, and the indirect effects on stress through maladaptive coping were larger for the HT/CVD sample. Results suggest procrastination is a vulnerability factor for poor adjustment to and management of HT/CVD. PMID:25804373

  11. Testing the free radical theory of aging in bats.

    PubMed

    Brunet Rossinni, Anja K

    2004-06-01

    The extended longevity of bats, despite their high metabolic rates, may provide insight to patterns and mechanisms of aging. I tested the free radical theory of aging as an explanation for the extreme longevity of the little brown bat, Myotis lucifugus (maximum life span potential [MLSP] = 34 years). In a comparative study, I measured whole-organism oxygen consumption and mitochondrial hydrogen peroxide production in brain, heart, and kidney tissues from M. lucifugus and short-tailed shrews, Blarina brevicauda (MLSP = 2 years). As predicted by the free radical theory of aging, M. lucifugus produced approximately half the amount of hydrogen peroxide as B. brevicauda. In addition, I compared oxygen consumption and hydrogen peroxide production of adult (approximately 1 year) and juvenile (fully developed and fledged young of the year) M. lucifugus to assess oxidative damage to mitochondria (measured as an increase in hydrogen peroxide production) due to the high metabolic rate associated with flight. Contrary to my prediction, juveniles had significantly higher levels of hydrogen peroxide production than adults. I propose that the decreased free radical production in adults is the result of within-individual selection of efficient mitochondria due to selective pressure created by the high energetic demands of flight. PMID:15247075

  12. Radiofrequency Ablation (RFA): Development of a Flow Model for Bovine Livers for Extensive Bench Testing

    SciTech Connect

    Lubienski, Andreas Bitsch, Rudi G.; Lubienski, Katrin; Kauffmann, Guenter; Duex, Markus

    2006-12-15

    Purpose. To develop a flow model for bovine livers for extensive bench testing of technical improvements or procedure-related developments of radiofrequency ablation excluding animal experiments. Methods. The perfusion of bovine livers directly from the slaughterhouse was simulated in a liver perfusion tank developed for the experimental work. The liver perfusion medium used was a Tyrode solution prepared in accordance with physiologic criteria (as for liver transplants) which was oxygenated by an oxygenator and heated to 36.5 deg. C. Portal vein circulation was regulated via a flow- and pressure-controlled pump and arterial circulation using a dialysis machine. Flow rate and pressure were adjusted as for the physiology of a human liver converted to bovine liver conditions. The fluid discharged from the liver was returned into the perfusion system through the vena cava. Extendable precision swivel arms with the radiofrequency probe attached were mounted on the liver perfusion tank. RFA was conducted with the RF3000 generator and a 2 cm LeVeen needle (Boston Scientific, Ratingen, Germany) in a three-dimensional grid for precise localization of the generated thermolesions. Results. Four bovine livers weighing 8.4 {+-} 0.4 kg each were prepared, connected to the perfusion system, and consecutively perfused for the experiments. Mean arterial flow was 569 {+-} 43 ml/min, arterial pressure 120 mmHg, portovenous flow 1440 {+-} 305 ml/min, and portal pressure 10 mmHg. Macroscopic evaluation after the experiments revealed no thrombi within the hepatic vessels. A total of 136 RF thermolesions were generated with an average number of 34 per liver. Mean RF duration was 2:59 {+-} 2:01 min:sec with an average baseline impedance of 28.2 {+-} 3.4 ohms. The mean diameter of the thermolesions along the puncture channel was 22.98 {+-} 4.34 mm and perpendicular to the channel was 23.27 {+-} 4.82 mm. Conclusion. Extracorporeal perfusion of bovine livers with consecutive standardized RF

  13. Extension of the Contingency Naming Test to adult assessment: psychometric analysis in a college student sample.

    PubMed

    Riddle, Tara; Suhr, Julie

    2012-01-01

    The Contingency Naming Test (CNT; Taylor, Albo, Phebus, Sachs, & Bierl, 1987) was initially designed to assess aspects of executive functioning, such as processing speed and response inhibition, in children. The measure has shown initial utility in identifying differences in executive function among child clinical groups; however, there is an absence of adequate psychometric data for use with adults. The current study expanded psychometric data upward for use with a college student sample and explored the measure's test-retest reliability and factor structure. Performance in the adult sample showed continued improvement above child norms, consistent with theories of executive function development. Exploratory factor analysis showed that the CNT is most closely related to measures of processing speed, as well as elements of response inhibition within the latter trials. Overall, results from the current study provide added support for the utility of the CNT as a measure of executive functioning in young adults. However, more research is needed to determine patterns of performance among adult clinical groups, as well as to better understand how performance patterns may change in a broader age range, including middle and older adulthood. PMID:22432965

  14. 40 CFR 90.1204 - Maintenance, aging and testing of engines.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 21 2013-07-01 2013-07-01 false Maintenance, aging and testing of... Voluntary In-Use Testing § 90.1204 Maintenance, aging and testing of engines. (a) Prior to aging the engines... assure that the engines and equipment were properly used and maintained during the field aging...

  15. 40 CFR 90.1204 - Maintenance, aging and testing of engines.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 20 2011-07-01 2011-07-01 false Maintenance, aging and testing of... Voluntary In-Use Testing § 90.1204 Maintenance, aging and testing of engines. (a) Prior to aging the engines... assure that the engines and equipment were properly used and maintained during the field aging...

  16. 40 CFR 90.1204 - Maintenance, aging and testing of engines.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 20 2014-07-01 2013-07-01 true Maintenance, aging and testing of... Voluntary In-Use Testing § 90.1204 Maintenance, aging and testing of engines. (a) Prior to aging the engines... assure that the engines and equipment were properly used and maintained during the field aging...

  17. 40 CFR 90.1204 - Maintenance, aging and testing of engines.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 21 2012-07-01 2012-07-01 false Maintenance, aging and testing of... Voluntary In-Use Testing § 90.1204 Maintenance, aging and testing of engines. (a) Prior to aging the engines... assure that the engines and equipment were properly used and maintained during the field aging...

  18. 40 CFR 90.1204 - Maintenance, aging and testing of engines.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Maintenance, aging and testing of... Voluntary In-Use Testing § 90.1204 Maintenance, aging and testing of engines. (a) Prior to aging the engines... assure that the engines and equipment were properly used and maintained during the field aging...

  19. 41 CFR 300-80.8 - What must we do to apply for a test program extension?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 41 Public Contracts and Property Management 4 2012-07-01 2012-07-01 false What must we do to apply for a test program extension? 300-80.8 Section 300-80.8 Public Contracts and Property Management Federal Travel Regulation System GENERAL AGENCY REQUIREMENTS 80-RELOCATION EXPENSES TEST PROGRAMS § 300-80.8 What must we do to apply for a test...

  20. The status of computerized cognitive testing in aging: A systematic review

    PubMed Central

    Wild, Katherine; Howieson, Diane; Webbe, Frank; Seelye, Adriana; Kaye, Jeffrey

    2008-01-01

    Background Early detection of cognitive decline in the elderly has become of heightened importance in parallel with the recent advances in therapeutics. Computerized assessment may be uniquely suited to early detection of changes in cognition in the elderly. We present here a systematic review of the status of computer-based cognitive testing focusing on detection of cognitive decline in the aging population. Methods All studies purporting to assess or detect age-related changes in cognition or early dementia/mild cognitive impairment (MCI) by means of computerized testing were included. Each test battery was rated on availability of normative data, level of evidence for test validity and reliability, comprehensiveness, and usability. All published studies relevant to a particular computerized test were read by a minimum of two reviewers, who completed rating forms containing the above-mentioned criteria. Results Of the 18 test batteries identified from the initial search, eleven were appropriate to cognitive testing in the elderly and were subjected to systematic review. Of those 11, five were either developed specifically for application with the elderly or have been used extensively with that population. Even within the computerized testing genre, great variability existed in manner of administration, ranging from fully examiner administered to fully self-administered. All tests had at least minimal reliability and validity data, commonly reported in peer-reviewed articles. However, level of rigor of validity testing varied widely. Conclusion All test batteries exhibited some of the strengths of computerized cognitive testing: standardization of administration and stimulus presentation, accurate measures of response latencies, automated comparison in real-time with an individual’s prior performance as well as with age-related norms, and efficiencies of staffing and cost. Some, such as the MCIS, adapted complicated scoring algorithms to enhance the information

  1. Test Series 4: seismic-fragility tests of naturally-aged Exide EMP-13 battery cells

    SciTech Connect

    Bonzon, L.L.; Hente, D.B.; Kukreti, B.M.; Schendel, J.; Tulk, J.D.; Janis, W.J.; Black, D.A.; Paulsen, G.D.; Aucoin, B.D.

    1985-03-01

    This report, the fourth in a test series of an extensive seismic research program, covers the testing of a 27-year old lead-antimony Exide EMP-13 cells from the recently decommissioned Shippingport Atomic Power Station. The Exide cells were tested in two configurations using a triaxial shake table: single-cell tests, rigidly mounted; and multicell (five-cell) tests, mounted in a typical battery rack. A total of nine electrically active cells was used in the two different cell configurations. None of the nine cells failed during the actual seismic tests when a range of ZPAs up to 1.5 g was imposed. Subsequent discharge capacity tests of five of the cells showed, however, that none of the cells could deliver the accepted standard of 80% of their rated electrical capacity for 3 hours. In fact, none of the 5 cells could deliver more than a 33% capacity. Two of the seismically tested cells and one untested, low capacity cell were disassembled for examination and metallurgical analyses. The inspection showed the cells to be in poor condition. The negative plates in the vicinity of the bus connections were extremely weak, the positive buses were corroded and brittle, negative and positive active material utilization was extremely uneven, and corrosion products littered the cells.

  2. Aging tests of full scale CMS muon cathode strip chambers

    SciTech Connect

    D. Acosta et al.

    2003-10-15

    Two CMS production Cathode Strip Chambers were tested for aging effects in the high radiation environment at the Gamma Irradiation Facility at CERN. The chambers were irradiated over a large area: in total, about 2.1 m{sup 2} or 700 m of wire in each chamber. The 40% Ar+50%CO{sub 2}+10%CF{sub 4} gas mixture was provided by an open-loop gas system for one of the chambers and by closed-loop recirculating gas system for the other. After accumulating 0.3-0.4 C per centimeter of a wire, which is equivalent to operation during about 30-50 years at the peak LHC luminosity, no significant changes in gas gain, chamber efficiency, and wire signal noise were observed for either of the two chambers. The only consistent signs of aging were a small increase in dark current from {approx}2 nA to {approx}10 nA per plane of 600 wires and a decrease of strip-to-strip resistance from 1000 G{Omega} to 10-100 G{Omega}. Disassembly of the chambers revealed deposits on the cathode planes, while the anode wires remained fairly clean.

  3. Age-Related Differences in Motor Coordination during Simultaneous Leg Flexion and Finger Extension: Influence of Temporal Pressure

    PubMed Central

    Hussein, Tarek; Yiou, Eric; Larue, Jacques

    2013-01-01

    Although the effect of temporal pressure on spatio-temporal aspects of motor coordination and posture is well established in young adults, there is a clear lack of data on elderly subjects. This work examined the aging-related effects of temporal pressure on movement synchronization and dynamic stability. Sixteen young and eleven elderly subjects performed series of simultaneous rapid leg flexions in an erect posture paired with ipsilateral index-finger extensions, minimizing the difference between heel and finger movement onsets. This task was repeated ten times under two temporal conditions (self-initiated [SI] vs. reaction-time [RT]). Results showed that, first, temporal pressure modified movement synchronization; the finger extension preceded swing heel-off in RT, and inversely in SI. Synchronization error and associated standard deviation were significantly greater in elderly than in young adults in SI only, i.e. in the condition where proprioception is thought to be crucial for temporal coordination. Secondly, both groups developed a significantly shorter mediolateral (ML) anticipatory postural adjustment duration in RT (high temporal pressure) than in SI. In both groups, this shortening was compensated by an increase in the anticipatory peak of centre-of-gravity (CoG) acceleration towards the stance-leg so that ML dynamic stability at foot-off, quantified with the “extrapolated centre-of-mass”, remained unchanged across temporal conditions. This increased CoG acceleration was associated with an increased anticipatory peak of ML centre-of-pressure shift towards the swing-leg in young adults only. This suggested that the ability to accelerate the CoG with the centre-of-pressure shift was degraded in elderly, probably due to weakness in the lower limb muscles. Dynamic stability at foot-off was also degraded in elderly, with a consequent increased risk of ML imbalance and falling. The present study provides new insights into the ability of elderly adults to

  4. Aging 5 Years in 5 Minutes: The Effect of Taking a Memory Test on Older Adults’ Subjective Age

    PubMed Central

    Hughes, Matthew L.; Geraci, Lisa; De Forrest, Ross L.

    2015-01-01

    How old one feels—one’s subjective age—has been shown to predict important psychological and health outcomes. The current studies examined the effect of taking a standard memory test on older adults’ subjective age. Study 1 showed that older adults felt older after taking a standard neuropsychological screening test and participating in a free-recall experiment than they felt at baseline. Study 2 showed that the effect was selective to older adults: Younger adults’ subjective age was not affected by participating in the memory experiment. Study 3 showed that the subjective-aging effect was specific to memory, as taking a vocabulary test for a similar amount of time did not affect older adults’ subjective age. Finally, Study 4 showed that simply expecting to take a memory test subjectively aged older adults. The results indicate that being in a memory-testing context affects older adults’ self-perception by making them feel older. PMID:24100121

  5. 78 FR 4120 - Notice of Request for Extension of Approval of an Information Collection; Tuberculosis Testing of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-18

    ... Animal and Plant Health Inspection Service Notice of Request for Extension of Approval of an Information Collection; Tuberculosis Testing of Imported Cattle From Mexico AGENCY: Animal and Plant Health Inspection... accordance with the Paperwork Reduction Act of 1995, this notice announces the Animal and Plant...

  6. 78 FR 23884 - Seed Testing Service Program; Request for an Extension of and Revision to a Currently Approved...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-23

    ... assist in the development of new and expanding markets. Under the program, samples of agricultural and... Agricultural Marketing Service Seed Testing Service Program; Request for an Extension of and Revision to a Currently Approved Information Collection AGENCY: Agricultural Marketing Service, USDA. ACTION: Request...

  7. Young Children's Extension of Novel Labels to Novel Animate Items in Three Testing Conditions

    ERIC Educational Resources Information Center

    Arias-Trejo, Natalia

    2010-01-01

    The present research explores young children's extension of novel labels to novel animate items. Three experiments were performed by means of the intermodal preferential looking (IPL) paradigm. In Experiment 1, after repeated exposure to novel word-object associations, 24- and 36-month-olds extend novel labels on the basis of shape similarity, in…

  8. Extended Aging of Ag/W Circuit Breaker Contacts: Influence on Surface Structure, Electrical Properties, and UL Testing Performance

    NASA Astrophysics Data System (ADS)

    Yu, Haibo; Kesim, M. Tumerkan; Sun, Yu; Harmon, Jason; Potter, Jonathan; Alpay, S. Pamir; Aindow, Mark

    2016-01-01

    Samples of 120 V, 30 A commercial circuit breakers were subjected to various aging treatments and the resulting microstructures at the surfaces of the Ag/W contacts were studied using a combination of x-ray diffraction, scanning electron microscopy, and energy-dispersive x-ray spectroscopy techniques. Breakers aged naturally in a hot, humid climate were compared to those subjected to accelerated aging in dry and humid environments. The most extensive oxidation was observed for contacts from breakers subjected to accelerated humid aging; these contacts exhibited thick surface layers consisting of Ag2O, Ag2WO4, Cu(OH)2•H2O, and WO3 phases. Far less surface degradation was observed for dry-aged contacts. Naturally aged contacts showed variations in degradation with more oxidation at the surface regions outside the physical contact area on the contact face. A correlation was found between the contact resistances measured from these samples following ASTM standard B 667-97 and the observed surface microstructures. To evaluate the effects of the surface oxides on breaker performance, humid-aged breakers were subjected to standardized UL overload/temperature-rise, endurance, and short-circuit testing following UL489. The contacts in these breakers exhibit similar microstructural and property changes to those observed previously for as-manufactured contacts after UL testing. These data illustrate the robust performance of this contact technology even after being subjected to aggressive artificial aging.

  9. 78 FR 694 - Proposed Extension of Approval of Information Collection; Comment Request-Testing and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-04

    ...As required by the Paperwork Reduction Act of 1995 (44 U.S.C. chapter 35), the Consumer Product Safety Commission (CPSC or Commission) requests comments on a proposed 3-year extension of approval of information collection requirements in the Standard for the Flammability--Open Flame--of Mattresses Sets (Open-Flame standard), 16 CFR part 1633. The Commission has a separate flammability standard......

  10. Above-Level Test Item Functioning across Examinee Age Groups

    ERIC Educational Resources Information Center

    Warne, Russell T.; Doty, Kristine J.; Malbica, Anne Marie; Angeles, Victor R.; Innes, Scott; Hall, Jared; Masterson-Nixon, Kelli

    2016-01-01

    "Above-level testing" (also called "above-grade testing," "out-of-level testing," and "off-level testing") is the practice of administering to a child a test that is designed for an examinee population that is older or in a more advanced grade. Above-level testing is frequently used to help educators design…

  11. A neuromusculoskeletal model to simulate the constant angular velocity elbow extension test of spasticity.

    PubMed

    Koo, Terry K K; Mak, Arthur F T

    2006-01-01

    We developed a neuromusculoskeletal model to simulate the stretch reflex torque induced during a constant angular velocity elbow extension by tuning a set of physiologically-based parameters. Our model extended past modeling efforts in the investigation of elbow spasticity by incorporating explicit musculotendon, muscle spindle, and motoneuron pool models in each prime elbow flexor. We analyzed the effects of changes in motoneuron pool and muscle spindle properties as well as muscle mechanical properties on the biomechanical behavior of the elbow joint observed during a constant angular velocity elbow extension. Results indicated that both motoneuron pool thresholds and gains could be substantially different among muscles. In addition, sensitivity analysis revealed that spindle static gain and motoneuron pool threshold were the most sensitive parameters that could affect the stretch reflex responses of the elbow flexors during a constant angular velocity elbow extension, followed by motoneuron pool gain, and spindle dynamic gain. It is hoped that the model will contribute to the understanding of the underlying mechanisms of spasticity after validation by more elaborate experiments, and will facilitate the future development of more specific treatment of spasticity. PMID:15908257

  12. 40 CFR 63.1112 - Extension of compliance, and performance test, monitoring, recordkeeping and reporting waivers...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... would not provide accurate measurements due to liquid water or other interferences caused by substances... the American Society for Testing and Materials (ASTM) test methods or sampling procedures specified...

  13. 40 CFR 63.1112 - Extension of compliance, and performance test, monitoring, recordkeeping and reporting waivers...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... would not provide accurate measurements due to liquid water or other interferences caused by substances... the American Society for Testing and Materials (ASTM) test methods or sampling procedures specified...

  14. The Frontal Hypothesis of Cognitive Aging: Factor Structure and Age Effects on Four "Frontal Tests" among Healthy Individuals

    ERIC Educational Resources Information Center

    Rodriguez-Aranda, Claudia; Sundet, Kjetil

    2006-01-01

    With 101 healthy aging adult participants, the authors investigated whether executive functions are a unitary concept. The authors established the factor structure of the Wisconsin Card Sorting Test (WCST; E. A. Berg, 1948), the Stroop color and word test (C. J. Golden, 1978), verbal fluency using the Controlled Oral Word Association Test (COWAT;…

  15. NASA Common Research Model Test Envelope Extension With Active Sting Damping at NTF

    NASA Technical Reports Server (NTRS)

    Rivers, Melissa B.; Balakrishna, S.

    2014-01-01

    The NASA Common Research Model (CRM) high Reynolds number transonic wind tunnel testing program was established to generate an experimental database for applied Computational Fluid Dynamics (CFD) validation studies. During transonic wind tunnel tests, the CRM encounters large sting vibrations when the angle of attack approaches the second pitching moment break, which can sometimes become divergent. CRM transonic test data analysis suggests that sting divergent oscillations are related to negative net sting damping episodes associated with flow separation instability. The National Transonic Facility (NTF) has been addressing remedies to extend polar testing up to and beyond the second pitching moment break point of the test articles using an active piezoceramic damper system for both ambient and cryogenic temperatures. This paper reviews CRM test results to gain understanding of sting dynamics with a simple model describing the mechanics of a sting-model system and presents the performance of the damper under cryogenic conditions.

  16. Prenatal Marijuana Exposure and Intelligence Test Performance at Age 6

    ERIC Educational Resources Information Center

    Goldschmidt, Lidush; Richardson, Gale A.; Willford, Jennifer; Day, Nancy L.

    2008-01-01

    A study was conducted on lower income population women who were moderate users of marijuana to examine the effects of prenatal marijuana exposure on children's intellectual development at the age of six. Results concluded that the Cognitive deficits noticed at the age of six were specific to verbal and quantitative reasoning and short-term memory.

  17. 76 FR 9374 - Proposed Extension of Existing Information Collection; Examinations and Testing of Electrical...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-17

    ... information collection for 30 CFR 75.351 Atmospheric monitoring systems; 75.512 Electric equipment; examination, testing and maintenance; 75.703 Grounding offtrack direct-current machines and enclosures of... overcurrent protection; testing and calibration requirements; records; 77.502 Electric equipment;...

  18. Psychological Reactance and Persuasive Health Communication: A Test and Extension of the Intertwined Model

    ERIC Educational Resources Information Center

    Rains, Stephen A.; Turner, Monique Mitchell

    2007-01-01

    This manuscript reports 2 experiments that were conducted to test and extend the work of J. P. Dillard and L. Shen (2005) examining the cognitive and affective processes involved in psychological reactance. In particular, the studies reported here (a) examined the best-fitting model of reactance processes and (b) tested 3 factors that may affect…

  19. The Rasch Model for Speed Tests and Some Extensions with Applications to Incomplete Designs.

    ERIC Educational Resources Information Center

    Jansen, Margo G. H.

    1997-01-01

    In the approach to latent trait models for pure speed tests presented in this article, the subject parameters are treated as random variables with a common gamma distribution, and marginal maximum likelihood estimators are derived for the test difficulties and the parameters of the latent subject distribution. An application of this model to…

  20. The [Alpha] and the [Omega] of Congeneric Test Theory: An Extension of Reliability and Internal Consistency to Heterogeneous Tests

    ERIC Educational Resources Information Center

    Lucke, Joseph F.

    2005-01-01

    Psychometric theory focuses primarily on tests that are homogeneous, measuring only one attribute of a psychosocial entity. However, the complexity of psychosocial behavior often requires tests that are heterogeneous, measuring more than one attribute. In this presentation, reliability and internal consistency are extended to heterogeneous tests…

  1. Methodology for designing accelerated aging tests for predicting life of photovoltaic arrays

    NASA Technical Reports Server (NTRS)

    Gaines, G. B.; Thomas, R. E.; Derringer, G. C.; Kistler, C. W.; Bigg, D. M.; Carmichael, D. C.

    1977-01-01

    A methodology for designing aging tests in which life prediction was paramount was developed. The methodology builds upon experience with regard to aging behavior in those material classes which are expected to be utilized as encapsulant elements, viz., glasses and polymers, and upon experience with the design of aging tests. The experiences were reviewed, and results are discussed in detail.

  2. Testing for Lorentz Violation: Constraints on Standard-Model-Extension Parameters via Lunar Laser Ranging

    SciTech Connect

    Battat, James B. R.; Chandler, John F.; Stubbs, Christopher W.

    2007-12-14

    We present constraints on violations of Lorentz invariance based on archival lunar laser-ranging (LLR) data. LLR measures the Earth-Moon separation by timing the round-trip travel of light between the two bodies and is currently accurate to the equivalent of a few centimeters (parts in 10{sup 11} of the total distance). By analyzing this LLR data under the standard-model extension (SME) framework, we derived six observational constraints on dimensionless SME parameters that describe potential Lorentz violation. We found no evidence for Lorentz violation at the 10{sup -6} to 10{sup -11} level in these parameters. This work constitutes the first LLR constraints on SME parameters.

  3. 78 FR 70324 - Thy Hydrostatic Testing Provision of the Portable Fire Extinguishers Standard; Extension of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-25

    ...OSHA solicits public comments concerning its proposal to extend the Office of Management and Budget's (OMB) approval of the information collection requirements contained in the Hydrostatic Testing provision of the Portable Fire Extinguishers Standard for General Industry (29 CFR...

  4. 14 CFR Special Federal Aviation... - Temporary Extension of Time To Allow for Certain Training and Testing

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... certification. 2. Special Qualification Requirements. The sections of 14 CFR that prescribes these requirements... Certain Training and Testing Federal Special Federal Aviation Regulation No. 93 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRMEN CERTIFICATION:...

  5. 14 CFR Special Federal Aviation... - Temporary Extension of Time To Allow for Certain Training and Testing

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... certification. 2. Special Qualification Requirements. The sections of 14 CFR that prescribes these requirements... Certain Training and Testing Federal Special Federal Aviation Regulation No. 93 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRMEN CERTIFICATION:...

  6. 77 FR 11367 - Defense Federal Acquisition Regulation Supplement; Extension of the Test Program for Negotiation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-24

    ...DoD is issuing a final rule amending the Defense Federal Acquisition Regulation Supplement to extend the program period for the DoD Test Program for Negotiation of Comprehensive Small Business Subcontracting...

  7. The validation of a French-language version of the Aging Perceptions Questionnaire (APQ) and its extension to a population aged 55 and over

    PubMed Central

    2012-01-01

    Background Several studies have shown the influence of the perceptions of aging on the cognitive functioning and the mental and physical health of older people. These relationships have not to date been studied in France where validated instruments are lacking. The primary objective of this study was to validate a French-language version of the Aging Perceptions Questionnaire (APQ) in the French general population aged 65 and over. The secondary objective was to study the stability of the dimensions of this instrument among participants aged 55 to 64. Methods The study was proposed to the cohort of the Observatoire Régional du Vieillissement (OPREVI) (observatory of aging), located in a small town in Poitou-Charentes (western France). An anonymous questionnaire including the APQ was sent by mail to inhabitants aged 55 and over. The original English language APQ was described with adults aged 65 and older. It has 32 items distributed on 7 dimensions: timeline chronic and cyclical, positive and negative consequences, positive and negative control and emotional representations. Results 656 adults participated in this survey (286 men, 370 women). Among those aged 65 and over (n = 394), the seven-factor structure estimated by confirmatory factor analysis was coherent with original findings. Internal consistency as evaluated by Cronbach alpha, was between 0.83 for consequences negative and 0.52 for control negative. Several dimensions were strongly correlated. Among participants aged 55 to 64 (n = 262), the same factorial model yielded an acceptable fit. Multi-group confirmatory factor analysis concluded to approximate factorial invariance between the two age groups with a null delta in comparative fit index. Conclusion This study among French people aged 65 and over, added further evidence of the multidimensional structure of the French version of the APQ which is superimposed to the dimensions of the original Irish version. The same factorial structure applies

  8. What's in a Topic? Exploring the Interaction between Test-Taker Age and Item Content in High-Stakes Testing

    ERIC Educational Resources Information Center

    Banerjee, Jayanti; Papageorgiou, Spiros

    2016-01-01

    The research reported in this article investigates differential item functioning (DIF) in a listening comprehension test. The study explores the relationship between test-taker age and the items' language domains across multiple test forms. The data comprise test-taker responses (N = 2,861) to a total of 133 unique items, 46 items of which were…

  9. Extension of similarity test procedures to cooled engine components with insulating ceramic coatings

    NASA Astrophysics Data System (ADS)

    Gladden, H. J.

    1980-05-01

    Material thermal conductivity was analyzed for its effect on the thermal performance of air cooled gas turbine components, both with and without a ceramic thermal-barrier material, tested at reduced temperatures and pressures. The analysis shows that neglecting the material thermal conductivity can contribute significant errors when metal-wall-temperature test data taken on a turbine vane are extrapolated to engine conditions. This error in metal temperature for an uncoated vane is of opposite sign from that for a ceramic-coated vane. A correction technique is developed for both ceramic-coated and uncoated components.

  10. Productive Extension of Semantic Memory in School-Aged Children: Relations with Reading Comprehension and Deployment of Cognitive Resources

    ERIC Educational Resources Information Center

    Bauer, Patricia J.; Blue, Shala N.; Xu, Aoxiang; Esposito, Alena G.

    2016-01-01

    We investigated 7- to 10-year-old children's productive extension of semantic memory through self-generation of new factual knowledge derived through integration of separate yet related facts learned through instruction or through reading. In Experiment 1, an experimenter read the to-be-integrated facts. Children successfully learned and…

  11. Assessing age in the desert tortoise Gopherus agassizii: Testing skeletochronology with individuals of known age

    USGS Publications Warehouse

    Curtin, A.J.; Zug, G.R.; Medica, P.A.; Spotila, J.R.

    2008-01-01

    Eight desert tortoises Gopherus agassizii from a long-term mark-recapture study in the Mojave Desert, Nevada, USA, afforded an opportunity to examine the accuracy of skeletochronological age estimation on tortoises from a seasonal, yet environmentally erratic environment. These 8 tortoises were marked as hatchlings or within the first 2 yr of life, and their carcasses were salvaged from predator kills. Using d blind protocol, 2 skeletochronological protocols (correction-factor and ranking) provided age estimates for a set of 4 bony elements (humerus, scapula, femur, ilium) from these tortoises of known age. The age at death of the tortoises ranged from 15 to 50 yr. The most accurate protocol - ranking using the growth layers within each of the 4 elements - provided estimates from 21 to 47 yr, with the highest accuracy from the ilia. The results indicate that skeletochronological age estimation provides a reasonably accurate method for assessing the age at death of desert tortoises and, if used with a large sample of individuals, will provide a valuable tool for examining age-related mortality parameters in desert tortoise and likely in other gopher tortoises (Gopherus). ?? Inter-Research 2008.

  12. 75 FR 9953 - Definition and Requirements for a Nationally Recognized Testing Laboratory (NRTL); Extension of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-04

    ... Act of 1995 (44 U.S.C. 3506 ] et seq.), and Secretary of Labor's Order No. 5-2007 (72 FR 31160... Occupational Safety and Health Administration Definition and Requirements for a Nationally Recognized Testing... information collection requirements specified by its Regulation on the Definition and Requirements for...

  13. 75 FR 48728 - The Hydrostatic Testing Provision of the Portable Fire Extinguishers Standard; Extension of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-11

    ... CFR 1910.157(f)(16)). DATES: Comments must be submitted (postmarked, sent, or received) by October 12.... Test Records (Sec. 1910.157(f)(16)) Paragraph (f)(16) requires employers to develop and maintain a... the intervals specified in Sec. 1910.157(f)(16), thereby ensuring that they will operate properly...

  14. 78 FR 45010 - Modifications to the Disability Determination Procedures; Extension of Testing of Some Disability...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-25

    ... FR 47218. Currently, the ] prototype combines the single decisionmaker approach described above with... from September 28, 2012 to September 27, 2013. 77 FR 35464. We are extending case selection for the... and 416.1406. These rules authorize us to test several modifications to the disability...

  15. 77 FR 35464 - Modifications to the Disability Determination Procedures; Extension of Testing of Some Disability...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-13

    ...,'' in 10 States. 64 FR 47218. Currently, the prototype combines the single decisionmaker approach... September 24, 2009, we extended the time period until September 28, 2012. 74 FR 48797. We have decided to... and 416.1406. These rules authorize us to test several modifications to the disability...

  16. Algorithms for Developing Test Questions from Sentences in Instructional Materials: An Extension of an Earlier Study.

    ERIC Educational Resources Information Center

    Roid, Gale H.; And Others

    An earlier study was extended and replicated to examine the feasibility of generating multiple-choice test questions by transforming sentences from prose instructional material. In the first study, a computer-based algorithm was used to analyze prose subject matter and to identify high-information words. Sentences containing selected words were…

  17. 76 FR 24060 - Proposed Extension of Existing Information Collection; Testing, Evaluation, and Approval of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-29

    ... Web site: select ``Rules & Regs'' on the right side of the screen; then select ``FR Docs''; and under..., Evaluation, and Approval of Mining Products AGENCY: Mine Safety and Health Administration. ACTION: Notice of... inspection, testing, approval and certification, and quality control of mining equipment and...

  18. The role of performance validity tests in the assessment of cognitive functioning after military concussion: A replication and extension.

    PubMed

    Armistead-Jehle, Patrick; Cooper, Douglas B; Vanderploeg, Rodney D

    2016-01-01

    The current investigation is a replication and extension of a previously published study by Cooper, Vanderploeg, Armistead-Jehle, Lewis, and Bowles (2014) demonstrating that performance validity test scores accounted for more variance in cognitive testing among service members with a history of concussion than did demographic variables, etiology of and time since injury, and symptom severity. The present study included a sample of 142 active-duty service members evaluated following a suspected or confirmed history of mild traumatic brain injury. Participants completed a battery of neuropsychological measures that included scales of performance and symptom validity (specifically the Medical Symptom Validity Test, Nonverbal Medical Symptom Validity Test, and Personality Assessment Inventory). Among the factors considered in the current study, performance validity test results accounted for the most variance in cognitive test scores, above demographic, concussion history, symptom validity, and psychological distress variables. Performance validity test results were modestly related to symptom validity as measured by the Personality Assessment Inventory Negative Impression Management scale. In sum, the current results replicated the original Cooper et al. study and highlight the importance of including performance validity tests as part of neurocognitive evaluation, even in clinical contexts, within this population. PMID:26569384

  19. U-Pb geochronologic constraints on the age of thrusting, crustal extension, peraluminous plutonism in the Little Rincon Mountains, southern Arizona

    SciTech Connect

    Gehrels, G.E.; Smith, C.H. )

    1991-03-01

    The Little Rincon thrust fault is a mylonitic shear zone that juxtaposes Middle Proterozoic Continental Granodiorite over metasedimentary rocks of Proterozoic and early Paleozoic age. This fault is structurally beneath the San Pedro detachment fault and associated ductile deformational fabrics, which formed during early Oligocene to early Miocene time. A syntectonic leucogranite sill within the Little Rincon shear zone yields a U-Pb concordia-intercept age 66{plus minus}10 Ma for zircon and a concordant age 51{plus minus}2 Ma for fractions composed of monazite and xenotime. This demonstrates that compressional deformation in the Catalina and Rincon mountains is generally coeval with Laramide thrust faults that extend at least from southeastern California to southeastern Arizona. A peraluminous granite pluton that truncates the shear zone but displays extension-related fabrics yields a lower-intercept age 24{plus minus}12 Ma for zircon and an age of 30{plus minus}6 Ma for monazite. This indicates that some peraluminous plutons in the region were emplaced during regional crustal extension.

  20. Microstructures and crystallographic preferred orientations evolution in upper mantle rocks submitted to HT-HP extension tests

    NASA Astrophysics Data System (ADS)

    Ben-Ismail, W.; Tommasi, A.; Rutter, E.; Holloway, R.

    2003-04-01

    We analyse the changes in microstructure and the development of lattice preferred orientation (LPO) in upper mantle rocks deformed in extension. Extension experiments have been chosen because although the bulk extensional strain was under 50%, the non-linearity of the flow was sufficient to provoke the formation of a neck, in the center of which strain attained up to 1000%. These extension tests been performed using a gas medium, internally heated apparatus at 1200 deg C, 300 MPa confining pressure at an unloading rate of 0.015 mm/minutes corresponding to a strain rate of 10 5 S-1. The development of LPO as a function of strain has been studied in a natural harzburgite from the Oman ophiolite and two dunites from the Balmuccia massif in the Alps. The Oman harburgite is a fine-grained mylonite (500 to 10 micron) with a foliation marked by alignment of spinels and by a weak shape fabric of small olivine and enstatite porphyroclasts and a weak crystallographic preferred orientation. The extension tests resulted in the development of a new foliation marked by elongated olivine and spinel grains as well as in a significant grain size reduction by dynamic recrystallisation (mainly by bulging). This microstructure suggests that the deformation is accommodated by mainly by dislocation creep and, in the fine-grained, highly-recrystallised domains, also by grain boundary sliding. EBSD measurements made in a thin section parallel to the extension direction allow the investigation of the evolution of the crystallographic fabric as a function of finite strain. The dunites from the Balmuccia massif display a annealed microstructure characterized by polygonal grains of olivine (1 to 6 mm) displaying no internal deformation features. Although similar in microstructure one sample displays a strong [100](010) olivine LPO while the other is almost isotropic. For this sample, extension experiments have been performed in four different directions in respect to the original

  1. Aging, Neighborhood Attachment, and Fear of Crime: Testing Reciprocal Effects

    ERIC Educational Resources Information Center

    Oh, Joong-Hwan; Kim, Sangmoon

    2009-01-01

    This study attempts to examine the reciprocal effects between fear of crime and neighborhood attachment because aging is a critical factor in both discussions of fear of crime and neighborhood attachment (friendship, neighboring, social cohesion and trust, informal social control, and participation in neighborhood watch program). Using data from…

  2. Dual Processing Model for Medical Decision-Making: An Extension to Diagnostic Testing.

    PubMed

    Tsalatsanis, Athanasios; Hozo, Iztok; Kumar, Ambuj; Djulbegovic, Benjamin

    2015-01-01

    Dual Processing Theories (DPT) assume that human cognition is governed by two distinct types of processes typically referred to as type 1 (intuitive) and type 2 (deliberative). Based on DPT we have derived a Dual Processing Model (DPM) to describe and explain therapeutic medical decision-making. The DPM model indicates that doctors decide to treat when treatment benefits outweigh its harms, which occurs when the probability of the disease is greater than the so called "threshold probability" at which treatment benefits are equal to treatment harms. Here we extend our work to include a wider class of decision problems that involve diagnostic testing. We illustrate applicability of the proposed model in a typical clinical scenario considering the management of a patient with prostate cancer. To that end, we calculate and compare two types of decision-thresholds: one that adheres to expected utility theory (EUT) and the second according to DPM. Our results showed that the decisions to administer a diagnostic test could be better explained using the DPM threshold. This is because such decisions depend on objective evidence of test/treatment benefits and harms as well as type 1 cognition of benefits and harms, which are not considered under EUT. Given that type 1 processes are unique to each decision-maker, this means that the DPM threshold will vary among different individuals. We also showed that when type 1 processes exclusively dominate decisions, ordering a diagnostic test does not affect a decision; the decision is based on the assessment of benefits and harms of treatment. These findings could explain variations in the treatment and diagnostic patterns documented in today's clinical practice. PMID:26244571

  3. Dual Processing Model for Medical Decision-Making: An Extension to Diagnostic Testing

    PubMed Central

    Tsalatsanis, Athanasios; Hozo, Iztok; Kumar, Ambuj; Djulbegovic, Benjamin

    2015-01-01

    Dual Processing Theories (DPT) assume that human cognition is governed by two distinct types of processes typically referred to as type 1 (intuitive) and type 2 (deliberative). Based on DPT we have derived a Dual Processing Model (DPM) to describe and explain therapeutic medical decision-making. The DPM model indicates that doctors decide to treat when treatment benefits outweigh its harms, which occurs when the probability of the disease is greater than the so called “threshold probability” at which treatment benefits are equal to treatment harms. Here we extend our work to include a wider class of decision problems that involve diagnostic testing. We illustrate applicability of the proposed model in a typical clinical scenario considering the management of a patient with prostate cancer. To that end, we calculate and compare two types of decision-thresholds: one that adheres to expected utility theory (EUT) and the second according to DPM. Our results showed that the decisions to administer a diagnostic test could be better explained using the DPM threshold. This is because such decisions depend on objective evidence of test/treatment benefits and harms as well as type 1 cognition of benefits and harms, which are not considered under EUT. Given that type 1 processes are unique to each decision-maker, this means that the DPM threshold will vary among different individuals. We also showed that when type 1 processes exclusively dominate decisions, ordering a diagnostic test does not affect a decision; the decision is based on the assessment of benefits and harms of treatment. These findings could explain variations in the treatment and diagnostic patterns documented in today’s clinical practice. PMID:26244571

  4. Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study

    PubMed Central

    2012-01-01

    Background This study undertakes a systematic and comprehensive analysis of brain gene expression profiles of immune/inflammation-related genes in aging and Alzheimer’s disease (AD). Methods In a well-powered microarray study of young (20 to 59 years), aged (60 to 99 years), and AD (74 to 95 years) cases, gene responses were assessed in the hippocampus, entorhinal cortex, superior frontal gyrus, and post-central gyrus. Results Several novel concepts emerge. First, immune/inflammation-related genes showed major changes in gene expression over the course of cognitively normal aging, with the extent of gene response far greater in aging than in AD. Of the 759 immune-related probesets interrogated on the microarray, approximately 40% were significantly altered in the SFG, PCG and HC with increasing age, with the majority upregulated (64 to 86%). In contrast, far fewer immune/inflammation genes were significantly changed in the transition to AD (approximately 6% of immune-related probesets), with gene responses primarily restricted to the SFG and HC. Second, relatively few significant changes in immune/inflammation genes were detected in the EC either in aging or AD, although many genes in the EC showed similar trends in responses as in the other brain regions. Third, immune/inflammation genes undergo gender-specific patterns of response in aging and AD, with the most pronounced differences emerging in aging. Finally, there was widespread upregulation of genes reflecting activation of microglia and perivascular macrophages in the aging brain, coupled with a downregulation of select factors (TOLLIP, fractalkine) that when present curtail microglial/macrophage activation. Notably, essentially all pathways of the innate immune system were upregulated in aging, including numerous complement components, genes involved in toll-like receptor signaling and inflammasome signaling, as well as genes coding for immunoglobulin (Fc) receptors and human leukocyte antigens I

  5. Neuropsychological Testing in a Rural African School-Age Population: Evaluating Contributions to Variability in Test Performance

    ERIC Educational Resources Information Center

    Kitsao-Wekulo, Patricia K.; Holding, Penny A.; Taylor, H. Gerry; Abubakar, Amina; Connolly, Kevin

    2013-01-01

    This study investigated the psychometric properties of a number of neuropsychological tests adapted for use in sub-Saharan Africa. A total of 308 school-age children in a predominantly rural community completed the tests. These tests were developed to assess skills similar to those measured by assessments of cognitive development published for use…

  6. Spatial contrast sensitivity - Effects of age, test-retest, and psychophysical method

    NASA Technical Reports Server (NTRS)

    Higgins, Kent E.; Jaffe, Myles J.; Caruso, Rafael C.; Demonasterio, Francisco M.

    1988-01-01

    Two different psychophysical methods were used to test the spatial contrast sensitivity in normal subjects from five age groups. The method of adjustment showed a decline in sensitivity with increasing age at all spatial frequencies, while the forced-choice procedure showed an age-related decline predominantly at high spatial frequencies. It is suggested that a neural component is responsible for this decline.

  7. Determination of hyperelastic properties for umbilical artery in preeclampsia from uniaxial extension tests

    PubMed Central

    Dodson, R. Blair; Martin, John T.; Hunter, Kendall S.; Ferguson, Virginia L.

    2013-01-01

    Objective Preeclampsia often results in altered hemodynamics and structurally remodeled umbilical arteries in the fetus – alterations that may be associated with arterial stiffening. We therefore hypothesized that the mechanical function of preeclamptic (PE) umbilical arteries had increased stiffness compared to control. Study design Umbilical arteries were collected from control (n = 9) and PE (n = 6) pregnancies without any other complications. Samples were tested uniaxially in axial and circumferential directions for the passive mechanics. The umbilical artery was modeled as a fiber reinforced hyperelastic material in both control and PE conditions. Results The PE arteries were stiffer than control arteries at stresses of 20–160 mmHg in the axial direction and 65–200 mmHg in the circumferential direction (P < 0.05). The PE umbilical arteries exhibited a 58% and 48% increase in circumferential moduli at the systolic and diastolic blood pressure respectively compared to the controls (P < 0.05). A hyperelastic model showed a substantial increase in both isotropic and anisotropic contribution in the mechanical behavior. Collectively, the changes observed correlated to a higher collagen fiber density in the PE group with increased hyperelastic material parameters (P < 0.05). Conclusion PE umbilical arteries demonstrated stiffer biomechanics compared to the controls due to the change in collagen fiber content. These altered biomechanical and structural changes provide a potential snapshot into systemic vasculature remodeling occurring in the newborn. PMID:23548660

  8. Accelerated aging and flashover tests on 138 kV nonceramic line post insulators

    SciTech Connect

    Schneider, H.M.; Guidi, W.W. ); Burnham, J.T. ); Gorur, R.S. ); Hall, J.F. )

    1993-01-01

    The behavior of 138 kV nonceramic line post insulators is investigated by means of clean fog tests conducted before and after aging in a specially designed accelerated aging chamber. The laboratory aging cycles are justified on the basis of actual weather in the coastal regions of Florida. Analytical measurements quantifying the degree of artificial aging are discussed and comparisons of artificial aging with service experience are presented. Observations of audible noise and radio influence voltage during the clean fog tests are reported.

  9. The unexpected outcomes of anti-aging, rejuvenation, and life extension studies: an origin of modern therapies.

    PubMed

    Stambler, Ilia

    2014-06-01

    The search for life-extending interventions has been often perceived as a purely academic pursuit, or as an unorthodox medical enterprise, with little or no practical outcome. Yet, in fact, these studies, explicitly aiming to prolong human life, often constituted a formidable, though hardly ever acknowledged, motivation for biomedical research and discovery. At least several modern biomedical fields have originated directly from rejuvenation and life extension research: (1) Hormone replacement therapy was born in Charles-Edouard Brown-Séquard's rejuvenation experiments with animal gland extracts (1889). (2) Probiotic diets originated in Elie Metchnikoff's conception of radically prolonged "orthobiosis" (c. 1900). (3) The development of clinical endocrinology owed much to Eugen Steinach's "endocrine rejuvenation" operations (c. 1910s-1920s). (4) Tissue transplantations in humans (allografts and xenografts) were first widely performed in Serge Voronoff's "rejuvenation by grafting" experiments (c. 1910s-1920s). (5) Tissue engineering was pioneered during Alexis Carrel's work on cell and tissue immortalization (c. 1900-1920). (6) Cell therapy (and particularly human embryonic cell therapy) was first widely conducted by Paul Niehans for the purposes of rejuvenation as early as the 1930s. Thus, the pursuit of life extension and rejuvenation has constituted an inseparable and crucial element in the history of biomedicine. Notably, the common principle of these studies was the proactive maintenance of stable, long-term homeostasis of the entire organism. PMID:24524368

  10. Opportunities for embryo transfer in the age of DNA testing

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Embryo transfer (ET) has contributed to increasing selection intensity in cattle breeding for many years. Preimplantation DNA testing offers the opportunity to increase selection response further through increasing within-family selection intensity. Further increases in between-family selection inte...

  11. Memory for Names Test Provides a Useful Confrontational Naming Task for Aging and Continuum of Dementia

    PubMed Central

    Brouillette, Robert M.; Martin, Corby K.; Correa, John B.; Davis, Allison B.; Han, Hongmei; Johnson, William D.; Foil, Heather C.; Hymel, Aimee; Keller, Jeffrey N.

    2014-01-01

    There is an increasing need to develop new neuropsychometric tools sensitive enough to detect subtle declines in cognitive performance during normal aging, as well as to distinguish between normal aging and the earliest stages of dementia. In this study, we report our findings regarding a new confrontational naming test, the Memory for Names test. We conducted evaluations utilizing a cohort of 234 elderly participants who comprised a spectrum of cognitive function ranging from normal for age (Uniform Data Set Overall Appraisal = 2, Clinical Dementia Rating = 0) to demented (Clinical Dementia Rating = 1–2, Mini Mental Status Examination Total Score <25). The Memory for Names test was found to measure the same cognitive construct as the Boston Naming Test. In conclusion, the Memory for Names test is a reliable and valid measure of age-related cognitive function that can discriminate between normal aging and mild cognitive impairment, and between mild cognitive impairment and dementia. PMID:21304184

  12. Memory for names test provides a useful confrontational naming task for aging and continuum of dementia.

    PubMed

    Brouillette, Robert M; Martin, Corby K; Correa, John B; Davis, Allison B; Han, Hongmei; Johnson, William D; Foil, Heather C; Hymel, Aimee; Keller, Jeffrey N

    2011-01-01

    There is an increasing need to develop new neuropsychometric tools sensitive enough to detect subtle declines in cognitive performance during normal aging, as well as to distinguish between normal aging and the earliest stages of dementia. In this study, we report our findings regarding a new confrontational naming test, the Memory for Names test. We conducted evaluations utilizing a cohort of 234 elderly participants who comprised a spectrum of cognitive function ranging from normal for age (Uniform Data Set Overall Appraisal = 2, Clinical Dementia Rating = 0) to demented (Clinical Dementia Rating = 1-2, Mini Mental Status Examination Total Score <25). The Memory for Names test was found to measure the same cognitive construct as the Boston Naming Test. In conclusion, the Memory for Names test is a reliable and valid measure of age-related cognitive function that can discriminate between normal aging and mild cognitive impairment, and between mild cognitive impairment and dementia. PMID:21304184

  13. Acceptance of Genetic Testing in a General Population: Age, Education and Gender Differences.

    ERIC Educational Resources Information Center

    Aro, A. R.; Hakonen, A.; Hietala, M.; Lonnqvist, J.; Niemela, P.; Peltonen, L; Aula, P.

    1997-01-01

    Effects of age, education, and gender on acceptance of genetic testing were studied. Finnish participants responded to a questionnaire presenting reasons for and against genetic testing (N=1,967). Intentions to take genetic tests, worries, and experience of genetic test or hereditary disease were also assessed. Results are presented and discussed.…

  14. Elementary School-Age Children's Capacity To Choose Positive Diagnostic and Negative Diagnostic Tests.

    ERIC Educational Resources Information Center

    Samuels, Mark C.; McDonald, John

    2002-01-01

    Two experiments compared 10-year-olds' and adults' ability to choose positive and negative diagnostic tests over positive and negative nondiagnostic tests. Findings indicated that both age groups were more likely to prefer positive diagnostic tests over positive nondiagnostic tests, although only adults showed a significant preference for negative…

  15. A new golden age: testing general relativity with cosmology.

    PubMed

    Bean, Rachel; Ferreira, Pedro G; Taylor, Andy

    2011-12-28

    Gravity drives the evolution of the Universe and is at the heart of its complexity. Einstein's field equations can be used to work out the detailed dynamics of space and time and to calculate the emergence of large-scale structure in the distribution of galaxies and radiation. Over the past few years, it has become clear that cosmological observations can be used not only to constrain different world models within the context of Einstein gravity but also to constrain the theory of gravity itself. In this article, we look at different aspects of this new field in which cosmology is used to test theories of gravity with a wide range of observations. PMID:22084284

  16. Use of U-Pb ages of detrital zircons to infer maximum depositional ages of strata: A test against a Colorado Plateau Mesozoic database

    NASA Astrophysics Data System (ADS)

    Dickinson, William R.; Gehrels, George E.

    2009-10-01

    We test the research strategy of using youngest U-Pb ages of detrital zircons to constrain the maximum depositional ages of strata containing the zircon grains by comparing U-Pb ages of detrital zircons in 58 samples of Mesozoic sandstone from the Colorado Plateau and adjacent areas with depositional ages known independently from biostratigraphy. Our analysis confirms the validity of the research strategy but indicates that results vary somewhat depending upon how youngest grain age is specified. We use four alternate measures of youngest age which vary from least to most statistically robust as follows: (a) youngest single grain age, (b) youngest graphical age peak controlled by more than one grain age; (c) mean age of the youngest two or more grains that overlap in age at 1 σ, (d) mean age of the youngest three or more grains that overlap in age at 2 σ. We also calculated the "youngest detrital zircon age" generated by Isoplot 2008 but do not recommend that model age as a youngest-age measure. In general, the youngest-age measures based on multiple grain ages are more consistently compatible with depositional ages, but the youngest single grain ages are compatible with depositional age for > 90% of samples, and lie within 5 Ma of depositional age for ~60% of samples. Selected minor discrepancies between youngest grain age and depositional age may reflect stratigraphic miscorrelations rather than errors in U-Pb geochronology.

  17. Effects of aging on responses to isoproterenol tilt-table testing in patients with syncope.

    PubMed

    Sheldon, R

    1994-09-01

    The diagnosis of neuromediated syncope is often established with isoproterenol head-up tilt-table testing. Previous work has demonstrated changes in autonomic nervous system function with progressive age, suggesting that responses to tilt-table testing may depend on the age of the patient. The purpose of this study was to assess the effects of age on the clinical and hemodynamic responses to isoproterenol tilt testing in patients with syncope of undetermined etiology. Accordingly, 85 patients with syncope of undetermined etiology underwent tilt testing with infusions of 0, 2, and 5 micrograms/min of isoproterenol in 3 successive stages. Of 85 patients tested, 66 had a positive outcome. The proportions of patients with a positive test and with tests ending in syncope declined significantly with age, with positive outcomes seen in 100%, 86%, 69%, and 61% of patients aged 12 to 20, 21 to 35, 36 to 60, and 61 to 88 years, respectively (p = 0.033, chi-square). Presyncope developed more slowly in patients aged 61 to 88 years (half-time to presyncope 2.5 minutes) than in younger patients (half-times to presyncope 0.7 to 0.9 minute). There were no significant age-related changes in peak and trough systolic blood pressures and rate-pressure products, but trough heart rate increased significantly with age (r = 0.40, p = 0.003). In conclusion, the likelihood of a positive outcome to isoproterenol tilt-table testing declines with age. Older patients take longer to develop presyncope, are less likely to develop syncope, and are less able to develop a relative bradycardia. These results guide interpretation of isoproterenol tilt-table testing. PMID:8059726

  18. Abuse of aging caregivers: test of a nursing intervention.

    PubMed

    Phillips, Linda R

    2008-01-01

    Although most women find it difficult to provide care to an older family member, some women face additional challenges and health risks because the care recipient is abusive or aggressive toward them. This study tested a 12-week psychoeducative nursing intervention intended to decrease the frequency and intensity of physical and verbal/psychological aggression toward older caregiving wives and daughters by care recipients and improve selected abuse-related outcomes. The intervention, which focused on pattern identification, advocacy counseling, reframing of the caregiving situation, and nonconfrontational caregiving strategies, was individualized and highly interactive with emphasis placed on mutual problem solving and mutual planning. Subjects included women older than 50 who provided care to elders older than 55. Subjects were randomly assigned to group (intervention, N = 38; control, N = 45) and data collectors were "blinded" to group assignment. Findings indicated the intervention significantly reduced frequency of verbal/psychological aggression, and feelings of anger for caregivers providing care to fathers or husbands. It was not effective for caregivers providing care to mothers, and it did not reduce burden. Implications for nursing include raising awareness about the special vulnerabilities of older caregivers, providing provocative new information about the gender-based power dynamics in caregiving situations and underscoring the need for nurses to assume a stronger leadership role in building science with regard to family caregiving. PMID:18497592

  19. Power Extension Package (PEP) system definition extension, orbital service module systems analysis study. Volume 9: PEP design, development and test plans

    NASA Technical Reports Server (NTRS)

    1979-01-01

    A plan for the production of two PEP flight systems is defined. The task's milestones are described. Provisions for the development and assembly of new ground support equipment required for both testing and launch operations are included.

  20. Age-Infusion Approach to Derive Injury Risk Curves for Dummies from Human Cadaver Tests

    PubMed Central

    Yoganandan, Narayan; Banerjee, Anjishnu; Pintar, Frank A.

    2015-01-01

    Injury criteria and risk curves are needed for anthropomorphic test devices (dummies) to assess injuries for improving human safety. The present state of knowledge is based on using injury outcomes and biomechanical metrics from post-mortem human subject (PMHS) and mechanical records from dummy tests. Data from these models are combined to develop dummy injury assessment risk curves (IARCs)/dummy injury assessment risk values (IARVs). This simple substitution approach involves duplicating dummy metrics for PMHS tested under similar conditions and pairing with PMHS injury outcomes. It does not directly account for the age of each specimen tested in the PMHS group. Current substitution methods for injury risk assessments use age as a covariate and dummy metrics (e.g., accelerations) are not modified so that age can be directly included in the model. The age-infusion methodology presented in this perspective article accommodates for an annual rate factor that modifies the dummy injury risk assessment responses to account for the age of the PMHS that the injury data were based on. The annual rate factor is determined using human injury risk curves. The dummy metrics are modulated based on individual PMHS age and rate factor, thus “infusing” age into the dummy data. Using PMHS injuries and accelerations from side-impact experiments, matched-pair dummy tests, and logistic regression techniques, the methodology demonstrates the process of age-infusion to derive the IARCs and IARVs. PMID:26697422

  1. Final Report: Drop Testing of Aged Stems on the SP981 Reservoir

    SciTech Connect

    White, M.B.

    1999-08-11

    Free fall drop testing of unloaded SP981 reservoirs was conducted by Savannah River Technology Center in the Materials Test Facility. The testing consisted of dropping eight aged and two unaged reservoirs on their stems at impact angles of 88 degrees and 70 degrees from heights of approximately 4 and 6 foot above a hardened steel surface.

  2. Histological and sex steroid hormone receptor changes in testes of immature, mature, and aged chickens.

    PubMed

    González-Morán, María Genoveva; Guerra-Araiza, Christian; Campos, María G; Camacho-Arroyo, Ignacio

    2008-11-01

    Sex steroid hormone receptors play a central role in the regulation of reproduction in male chickens. In this work, we evaluated by histomorphometric methods and Western blot analysis changes in the number of the different cell populations and in the content of sex steroid hormone receptors in testes from immature (1.5-month-old), mature (12-month-old), and aged (48-month-old) chickens. The number of Sertoli cells, germ cells, and Leydig cells per area of testicular tissue markedly changed according to chicken age. The highest number of Sertoli and Leydig cells was found in testes of immature chickens, with a dramatic decrease in those of mature chickens; however, the number of germ cells was the highest in mature chickens in comparison with other ages. The content of androgen receptor diminished in testes of mature and aged animals in comparison with that of immature chickens. In contrast, the content of estrogen receptor alpha and progesterone receptor was higher in testes of mature animals than in other ages. Both progesterone receptor isoforms were expressed in a similar proportion in testes of immature and mature animals. Interestingly, progesterone receptor isoform A was the predominant isoform in aged animals. These results suggest that there are marked age-dependent changes in chicken testes histology and in sex steroid hormone receptors content that should contribute to sex steroid hormone actions, in this tissue throughout the lifespan of chickens. PMID:18815005

  3. CANTAB object recognition and language tests to detect aging cognitive decline: an exploratory comparative study

    PubMed Central

    Cabral Soares, Fernanda; de Oliveira, Thaís Cristina Galdino; de Macedo, Liliane Dias e Dias; Tomás, Alessandra Mendonça; Picanço-Diniz, Domingos Luiz Wanderley; Bento-Torres, João; Bento-Torres, Natáli Valim Oliver; Picanço-Diniz, Cristovam Wanderley

    2015-01-01

    Objective The recognition of the limits between normal and pathological aging is essential to start preventive actions. The aim of this paper is to compare the Cambridge Neuropsychological Test Automated Battery (CANTAB) and language tests to distinguish subtle differences in cognitive performances in two different age groups, namely young adults and elderly cognitively normal subjects. Method We selected 29 young adults (29.9±1.06 years) and 31 older adults (74.1±1.15 years) matched by educational level (years of schooling). All subjects underwent a general assessment and a battery of neuropsychological tests, including the Mini Mental State Examination, visuospatial learning, and memory tasks from CANTAB and language tests. Cluster and discriminant analysis were applied to all neuropsychological test results to distinguish possible subgroups inside each age group. Results Significant differences in the performance of aged and young adults were detected in both language and visuospatial memory tests. Intragroup cluster and discriminant analysis revealed that CANTAB, as compared to language tests, was able to detect subtle but significant differences between the subjects. Conclusion Based on these findings, we concluded that, as compared to language tests, large-scale application of automated visuospatial tests to assess learning and memory might increase our ability to discern the limits between normal and pathological aging. PMID:25565785

  4. Reliability of the Raven Colored Progressive Matrices Test: Age and Ethnic Group Comparisons.

    ERIC Educational Resources Information Center

    Carlson, Jerry S.; Jensen, C. Mark

    1981-01-01

    Reliabilities for the Raven Colored Progressive Matrices Test (CPM) are reported for three age groups (ages 5 1/2- 6 1/2, 6 1/2-7 1/2, and 7 1/2-8 1/2 years) and three ethnic groups (Anglo, Black, and Hispanic). Results indicate CPM is not equally reliable for all age groups, but appears equally reliable for the three ethnic groups. (Author)

  5. Age Differences in Perseveration: Cognitive and Neuroanatomical Mediators of Performance on the Wisconsin Card Sorting Test

    ERIC Educational Resources Information Center

    Head, Denise; Kennedy, Kristen M.; Rodrigue, Karen M.; Raz, Naftali

    2009-01-01

    Aging effects on the Wisconsin Card Sorting Test (WCST) are fairly well established but the mechanisms of the decline are not clearly understood. In this study, we examined the cognitive and neural mechanisms mediating age-related increases in perseveration on the WCST. MRI-based volumetry and measures of selected executive functions in…

  6. Does Relative Age Influence Motor Test Performance of Fourth Grade Pupils?

    ERIC Educational Resources Information Center

    Wattie, Nick; Tietjens, Maike; Schorer, Jörg; Ghanbari, Marie-Christine; Strauss, Bernd; Seidel, Ilka; Baker, Joseph

    2014-01-01

    The aim of the current study was to explore relative age's influence on physical and motor tests among fourth grade children (9 to 10 years) from Germany. Data from 1218 children (49% female) who had performed the German Motor Ability Test (Bös et al., 2009) were analysed. The test battery, which was comprised of physical and motor tests,…

  7. This Is Only a Test: Teaching for Mathematical Understanding in an Age of Standardized Testing

    ERIC Educational Resources Information Center

    Litton, Nancy; Wickett, Maryann

    2009-01-01

    "This Is Only a Test" helps teachers plan a year of instruction that takes testing into account while staying focused on a curriculum that encourages students to love and understand mathematics. Transform teachers' and students' feelings toward standardized tests from panic and anxiety to control and confidence. This book's proven strategies help…

  8. Knowledge, attitude and practice of the smear test and its relation with female age 1

    PubMed Central

    Silveira, Nara Sibério Pinho; Vasconcelos, Camila Teixeira Moreira; Nicolau, Ana Izabel Oliveira; Oriá, Mônica Oliveira Batista; Pinheiro, Patricia Neyva da Costa; Pinheiro, Ana Karina Bezerra

    2016-01-01

    Abstract Objective: to verify the association among the knowledge attitude and practice of women in relation to the smear test and the age range. Method: a cross-sectional research was undertaken, associated with the knowledge, attitude and practice survey at a Primary Health Care service. The sample consisted of 775 women, distributed in three age ranges: adolescent, young and elderly. Results: although high rates of inappropriate knowledge were found in all age ranges, it was significantly higher among the adolescents (p=0.000). A similar trend was found in the attitude component, with percentages of inappropriateness in adolescence that drop as age advances (p=0.000). Nevertheless, no statistical difference among the groups was found in terms of practice (p=0.852). Conclusion: the study demonstrated a relation between the age range and knowledge, attitude and practice of the smear test. PMID:27305183

  9. Evaluation of coated columbium test panels having application to a secondary nozzle extension for the RL10 rocket engine system, parts 1 and 2

    NASA Technical Reports Server (NTRS)

    Murphy, Kenneth S.; Castro, Joaquin H.

    1988-01-01

    The activity performed on the screening and evaluation of various coatings for application on columbium alloy test panels representative of a radiation-cooled nozzle extension for the RL10 rocket engine is summarized. Vendors and processes of candidate coatings were evaluated. Post engine test evaluations of the two selected coatings are discussed.

  10. Extension of the Test-Area methodology for calculating solid-fluid interfacial tensions in cylindrical geometry

    NASA Astrophysics Data System (ADS)

    Blas, Felipe J.; Mendiboure, Bruno

    2013-04-01

    We extend the well-known Test-Area methodology of Gloor et al. [J. Chem. Phys. 123, 134703 (2005)], 10.1063/1.2038827, originally proposed to evaluate the surface tension of planar fluid-fluid interfaces along a computer simulation in the canonical ensemble, to deal with the solid-fluid interfacial tension of systems adsorbed on cylindrical pores. The common method used to evaluate the solid-fluid interfacial tension invokes the mechanical relation in terms of the tangential and normal components of the pressure tensor relative to the interface. Unfortunately, this procedure is difficult to implement in the case of cylindrical geometry, and particularly complex in case of nonspherical molecules. Following the original work of Gloor et al., we perform free-energy perturbations due to virtual changes in the solid-fluid surface. In this particular case, the radius and length of the cylindrical pore are varied to ensure constant-volume virtual changes of the solid-fluid surface area along the simulation. We apply the modified methodology for determining the interfacial tension of a system of spherical Lennard-Jones molecules adsorbed inside cylindrical pores that interact with fluid molecules through the generalized 10-4-3 Steele potential recently proposed by Siderius and Gelb [J. Chem. Phys. 135, 084703 (2011)], 10.1063/1.3626804. We analyze the effect of pore diameter, density of adsorbed molecules, and fluid-fluid cutoff distance of the Lennard-Jones intermolecular potential on the solid-fluid interfacial tension. This extension, as the original Test-Area formulation, offers clear advantages over the classical mechanical route of computational efficiency, easy of implementation, and generality.

  11. Spectral characterization of HST calibration lamps: new Pt/Cr-Ne line catalogues and aging test

    NASA Astrophysics Data System (ADS)

    Kerber, Florian; Rosa, Michael R.; Sansonetti, Craig J.; Reader, Joseph; Nave, G.; Bristow, Paul; Fiorentino, Mauro; Lercher, Georg

    2004-10-01

    The Space Telescope European Coordinating Facility's (ST-ECF) lamp project, funded directly by the European Space Agency (ESA), is dedicated to the study of hollow cathode calibration lamps as they are used onboard the Hubble Space Telescope (HST). There are two main objectives: First, we have measured the spectra of Pt/Cr-Ne lamps in order to obtain accurate and reliable wavelengths for all emission lines between 115 and 320 nm. This wavelength range corresponds to the coverage provided by the Space Telescope Imaging Spectrograph (STIS) Echelle modes. Extensive laboratory measurements were performed at the National Institute of Standard and Technology (NIST) using their 10.7 m normal incidence spectrograph and a Fourier Transform Spectrograph. Until now no good laboratory wavelengths for Cr had been available and their addition has a major impact on the wavelength calibration, in particular in the near UV. The new line list is being used in conjunction with the physical instrument model of STIS which is employed to derive an improved wavelength calibration as part of the STIS Calibration Enhancement (STIS-CE) effort. Second, we attempt to gain a better understanding of the performance of such lamps and the physical processes involved in their long term operations. Among the issues studied are the change of the spectrum as a function of current, its change as a function of time and the tolerances of alignment. The bulk of the measurements were performed on flight spares from STIS and on new space qualified lamps for the accelerated aging test. The original flight lamps from the Faint Object Spectrograph (FOS) and the Goddard High Resolution Spectrograph (GHRS) are the only lamps ever to be measured after their return from space. Together with the spectra archived from six years of on-orbit operations they provide a unique data set for studying ageing effects in these lamps. The new Pt/Cr-Ne line list has been successfully applied in the STIS-CE effort. Thereby the

  12. Aging, Loss-of-Coolant Accident (LOCA), and high potential testing of damaged cables

    SciTech Connect

    Vigil, R.A.; Jacobus, M.J.

    1994-04-01

    Experiments were conducted to assess the effects of high potential testing of cables and to assess the survivability of aged and damaged cables under Loss-of-Coolant Accident (LOCA) conditions. High potential testing at 240 Vdc/mil on undamaged cables suggested that no damage was incurred on the selected virgin cables. During aging and LOCA testing, Okonite ethylene propylene rubber (EPR) cables with a bonded jacket experienced unexpected failures. The failures appear to be primarily related to the level of thermal aging and the presence of a bonded jacket that ages more rapidly than the insulation. For Brand Rex crosslinked polyolefin (XLPO) cables, the results suggest that 7 mils of insulation remaining should give the cables a high probability of surviving accident exposure following aging. The voltage necessary to detect when 7 mils of insulation remain on unaged Brand Rex cables is approximately 35 kVdc. This voltage level would almost certainly be unacceptable to a utility for use as a damage assessment tool. However, additional tests indicated that a 35 kvdc voltage application would not damage virgin Brand Rex cables when tested in water. Although two damaged Rockbestos silicone rubber cables also failed during the accident test, no correlation between failures and level of damage was apparent.

  13. Age effects on EEG correlates of the Wisconsin Card Sorting Test

    PubMed Central

    Dias, Nuno S; Ferreira, Daniela; Reis, Joana; Jacinto, Luís R; Fernandes, Luís; Pinho, Francisco; Festa, Joana; Pereira, Mariana; Afonso, Nuno; Santos, Nadine C; Cerqueira, João J; Sousa, Nuno

    2015-01-01

    Body and brain undergo several changes with aging. One of the domains in which these changes are more remarkable relates with cognitive performance. In the present work, electroencephalogram (EEG) markers (power spectral density and spectral coherence) of age-related cognitive decline were sought whilst the subjects performed the Wisconsin Card Sorting Test (WCST). Considering the expected age-related cognitive deficits, WCST was applied to young, mid-age and elderly participants, and the theta and alpha frequency bands were analyzed. From the results herein presented, higher theta and alpha power were found to be associated with a good performance in the WCST of younger subjects. Additionally, higher theta and alpha coherence were also associated with good performance and were shown to decline with age and a decrease in alpha peak frequency seems to be associated with aging. Additionally, inter-hemispheric long-range coherences and parietal theta power were identified as age-independent EEG correlates of cognitive performance. In summary, these data reveals age-dependent as well as age-independent EEG correlates of cognitive performance that contribute to the understanding of brain aging and related cognitive deficits. PMID:26216431

  14. Superheated-steam test of ethylene propylene rubber cables using a simultaneous aging and accident environment

    SciTech Connect

    Bennett, P.R.; St. Clair, S.D.; Gilmore, T.W.

    1986-06-01

    The superheated-steam test exposed different ethylene propylene rubber (EPR) cables and insulation specimens to simultaneous aging and a 21-day simultaneous accident environment. In addition, some insulation specimens were exposed to five different aging conditions prior to the 21-day simultaneous accident simulation. The purpose of this superheated-steam test (a follow-on to the saturated-steam tests (NUREG/CR-3538)) was to: (1) examine electrical degradation of different configurations of EPR cables; (2) investigate differences between using superheated-steam or saturated-steam at the start of an accident simulation; (3) determine whether the aging technique used in the saturated-steam test induced artificial degradation; and (4) identify the constituents in EPR that affect moisture absorption.

  15. Summary and Evaluation of NRC-Sponsored Stellite 6 Aging and Friction Tests

    SciTech Connect

    J. C. Watkins; K. G. DeWall; D. Bramwell

    1999-04-01

    This report describes four sets of tests sponsored by the U.S. Nuclear Regulatory Commission and conducted by the Idaho National Engineering and Environmental Laboratory. The tests support research addressing the need to provide assurance that motor-operated valves are able to perform their intended safety function, usually to open or close against specified (design basis) flow and pressure loads. One of the parameters that affects a gate valve's operability is the friction between the disc seats and the valve body seats. In most gate valves, these surfaces are hardfaced with Stellite 6, a cobalt-based alloy. The tests described in this report investigate the changes that occur in the friction as the Stellite 6 surfaces develop an oxide film as they age. Stellite 6 specimens were aged in a corrosion autoclave, the oxide films were examined and characterized, and the specimens were subjected to friction testing in a friction autoclave. A very thin oxide film formed after only a fe w days of natural aging. Even a very thin oxide film caused an increase in friction. The surface structure of the oxide film was dominated by a hard crystalline structure, such that the friction response was analogous to rubbing two pieces of sandpaper together. In the limited data provided by naturally aged specimens (78 days maximum exposure, very thin oxide films), the friction increased with greater aging time, approaching an as-yet-undetermined plateau. Although the thickness of the oxide film increased with greater aging time, the mechanical properties of the oxide film (larger granules with greater aging time) appeared to play a greater role in the friction response. Friction testing of specimens subjected to simulated in-service testing strokes at intervals during the aging process showed only a slight decrease in friction, compared to other specimens. Results from specimens subjected to accelerated aging were inconclusive, because of differences in the structure and comp osition

  16. Lateral Variations of Fission-Track Cooling Ages along the Southern Peruvian Coast Reveal Coast-Parallel Extension during the Eocene and Oligocene.

    NASA Astrophysics Data System (ADS)

    Noury, M.; Bernet, M.; Jaillard, E.; Sempere, T.

    2014-12-01

    Proterozoic metamorphic rocks largely crop out between ~14 and ~17°S along the coast of southern Peru. Previous thermochronological studies in this belt focused on the Late Neogene cooling history and yielded Late Paleozoic to mid-Cretaceous zircon U-Th/He and fission-track ages, and Late Cretaceous to Early Paleocene apatite fission-track ages. Our study aims at extending the fission-track database in the ~300 km-long, high-grade metamorphic Atico-Mollendo Block (AMB; 15.8-17.1°S), in order to understand the lateral variations of thermochronologic ages along the Pacific coast of southern Peru. We present new apatite and zircon fission-track ages from the AMB and interpret them along with the previously published dates from this block and its surrounding areas. The apatite fission-track data show a longitudinal variation pattern with two localized shifts from younger (60 Ma) to older (~90 Ma) dates, corresponding to the northwestern and southeastern borders of the AMB. These shifts coincide in the field with two major normal fault zones that strike perpendicular to the coast and bound the AMB, and had been understated until now. Given the offsetted ages, the faults were active after 60 Ma, and tilted the AMB down to the NW. This interpretation is consistent with the fact that the metamorphic grade of the basement increases towards the SE, and with the deposition between ~55 and 30 Ma of forearc continental deposits (Lower Moquegua Group) that exhibit numerous synsedimentary extensional features. The zircon fission-track age pattern is more complicated but can be interpreted either as (i) reflecting a partial reset of the whole area due to burial during the Jurassic and Early Cretaceous, or (ii) as the reactivation of an important Carboniferous detachment fault during the ~100-80 Ma interval. We suggest that this coast-parallel Eocene-Oligocene extension accommodated the counterclockwise block rotation of the southern Peruvian forearc that accompanied the

  17. Quantitative evaluation of material degradation of thermally aged duplex stainless steels using chemical immersion test

    NASA Astrophysics Data System (ADS)

    Yi, Y. S.; Shoji, T.

    1996-12-01

    In order to develop a non-destructive evaluation technique for detection of thermal aging embrittlement of duplex stainless steels, corrosion tests on unaged and aged specimens of cast duplex stainless steels were performed in 5 wt% HCl solution. After the immersion test, the dissolution rate of specimens was obtained by a dissolved depth measurement with an AFM. In the measurements of dissolved depths, a replica technique was used for easier handling and also for a possible field application of the AFM analysis method. Changes in corrosion properties by aging measured in terms of the dissolved depth after the immersion were compared with the changes in mechanical properties by aging embrittlement. The changes in corrosion properties of unaged and aged specimen were analyzed in relation to the microstructural change by thermal aging. Based upon insights on the immersion test results and the comparison of the changes in corrosion properties and mechanical properties, a possible non-destructive detection and evaluation technique for thermal aging embrittlement by spinodal decomposition is proposed.

  18. Reliability of squat and countermovement jump tests in children 6 to 8 years of age.

    PubMed

    Acero, Rafael Martin; Fernández-del Olmo, Miguel; Sánchez, Jose Andres; Otero, Xose Luis; Aguado, Xavier; Rodríguez, Ferran A

    2011-02-01

    The aim of this study was to determine the reliability of the squat jump test (SJ) and countermovement jump test (CMJ), in fifty-six children (30 girls and 26 boys) with ages ranging from 6 to 8 years. Each subject performed two evaluation sessions (T1, T2) with seven days between tests. The results show that the CMJ test has a high intratrial reproducibility in T1 and T2 measured through intraclass correlation coefficient (ICC ≥ 0.95). The ICC for the SJ test had a high value (0.99) only in T1. The variability for both tests among children under 9 years of age is higher than those reported for adult subjects in other studies. The intersession reliability was questionable with a high methodical error (ME= 9.86-15.1%, for the SJ and CMJ, respectively) and a significant worsening of the results of CMJ in T2 (p < .05). PMID:21467598

  19. Benefits of extensive recruitment effort persist during follow-ups and are consistent across age group and survey method. The TRAILS study

    PubMed Central

    2012-01-01

    Background Extensive recruitment effort at baseline increases representativeness of study populations by decreasing non-response and associated bias. First, it is not known to what extent increased attrition occurs during subsequent measurement waves among subjects who were hard-to-recruit at baseline and what characteristics the hard-to-recruit dropouts have compared to the hard-to-recruit retainers. Second, it is unknown whether characteristics of hard-to-recruit responders in a prospective population based cohort study are similar across age group and survey method. Methods First, we compared first wave (T1) easy-to-recruit with hard-to-recruit responders of the TRacking Adolescents’ Individual Lives Survey (TRAILS), a prospective population based cohort study of Dutch (pre)adolescents (at first wave: n = 2230, mean age = 11.09 (SD 0.56), 50.8% girls), with regard to response rates at subsequent measurement waves. Second, easy-to-recruit and hard-to-recruit participants at the fourth TRAILS measurement wave (n = 1881, mean age = 19.1 (SD 0.60), 52.3% girls) were compared with fourth wave non-responders and earlier stage drop-outs on family composition, socioeconomic position (SEP), intelligence (IQ), education, sociometric status, substance use, and psychopathology. Results First, over 60% of the hard-to-recruit responders at the first wave were retained in the sample eight years later at the fourth measurement wave. Hard-to-recruit dropouts did not differ from hard-to-recruit retainers. Second, extensive recruitment efforts for the web based survey convinced a population of nineteen year olds with similar characteristics as the hard-to-recruit eleven year olds that were persuaded to participate in a school-based survey. Some characteristics associated with being hard-to-recruit (as compared to being easy-to-recruit) were more pronounced among non-responders, resembling the baseline situation (De Winter et al.2005). Conclusions First, extensive

  20. Alpha-theta effects associated with ageing during the Stroop test.

    PubMed

    Nombela, Cristina; Nombela, Manuel; Castell, Pedro; García, Teodoro; López-Coronado, Juan; Herrero, María Trinidad

    2014-01-01

    The Stroop effect is considered as a standard attentional measure to study conflict resolution in humans. The response of the brain to conflict is supposed to change over time and it is impaired in certain pathological conditions. Neuropsychological Stroop test measures have been complemented with electroencephalography (EEG) techniques to evaluate the mechanisms in the brain that underlie conflict resolution from the age of 20 to 70. To study the changes in EEG activity during life, we recruited a large sample of healthy subjects of different ages that included 90 healthy individuals, divided by age into decade intervals, which performed the Stroop test while recording a 14 channel EEG. The results highlighted an interaction between age and stimulus that was focused on the prefrontal (Alpha and Theta band) and Occipital (Alpha band) areas. We concluded that behavioural Stroop interference is directly influenced by opposing Alpha and Theta activity and evolves across the decades of life. PMID:24867024

  1. Alpha-Theta Effects Associated with Ageing during the Stroop Test

    PubMed Central

    Nombela, Cristina; Nombela, Manuel; Castell, Pedro; García, Teodoro; López-Coronado, Juan; Herrero, María Trinidad

    2014-01-01

    The Stroop effect is considered as a standard attentional measure to study conflict resolution in humans. The response of the brain to conflict is supposed to change over time and it is impaired in certain pathological conditions. Neuropsychological Stroop test measures have been complemented with electroencephalography (EEG) techniques to evaluate the mechanisms in the brain that underlie conflict resolution from the age of 20 to 70. To study the changes in EEG activity during life, we recruited a large sample of healthy subjects of different ages that included 90 healthy individuals, divided by age into decade intervals, which performed the Stroop test while recording a 14 channel EEG. The results highlighted an interaction between age and stimulus that was focused on the prefrontal (Alpha and Theta band) and Occipital (Alpha band) areas. We concluded that behavioural Stroop interference is directly influenced by opposing Alpha and Theta activity and evolves across the decades of life. PMID:24867024

  2. A test of the Lamendin method of age estimation in South African canines.

    PubMed

    Ackermann, Anja; Steyn, Maryna

    2014-03-01

    Age estimation in unknown adult skeletons remains a considerable problem in forensic anthropology. In 1992, Lamendin et al. published a non-destructive method of age estimation on single rooted teeth. With this method, periodontosis and root transparency are judged against root height, and these are then used in regression formulae to estimate age. The aim of this study was to test the accuracy of the Lamendin method on a large sample of canines of South Africans, and if necessary to adapt the formulae for this population. A sample of known sex, age and population group was used. This included 537 upper and lower canines from 498 skulls, and included black males, black females, white males and white females. The age of the individuals ranged from 20 to 90 years. The original formulae gave relatively poor results, and in an attempt to obtain better accuracy the formulae were adapted with the current data. Even after adaptation of the formulae, the highest correlation between estimated age and actual age remained low (R(2)=0.41), with mean errors ranging between 12 and 15 years. Periodontosis was better correlated with age than root transparency. The accuracy of the method was found to be much lower than what was originally published, but probably reflects biological reality and is on a par with other methods of adult age estimation. PMID:24445081

  3. Odor-Specific Loss of Smell Sensitivity with Age as Revealed by the Specific Sensitivity Test.

    PubMed

    Seow, Yi-Xin; Ong, Peter K C; Huang, Dejian

    2016-07-01

    The perception of odor mixtures plays an important role in human food intake, behavior, and emotions. Decline of smell acuity with normal aging could impact food perception and preferences at various ages. However, since the landmark Smell Survey by National Geographic, little has been elucidated on differences in the onset and extent of loss in olfactory sensitivity toward single odorants. Here, using the Specific Sensitivity test, we show the onset and extent of loss in both identification and detection thresholds of odorants with age are odorant-specific. Subjects of Chinese descent in Singapore (186 women, 95 men), aged 21-80 years, were assessed for olfactory sensitivity of 10 odorants from various odor groups. Notably, subjects in their 70s required 179 times concentration of rose-like odorant (2-phenylethanol) than subjects in the 20s, while thresholds for onion-like 2-methyloxolane-3-thiol only differed by 3 times between the age groups. In addition, identification rate for 2-phenylethanol was negatively correlated with age throughout adult life whereas mushroom-like oct-1-en-3-ol was equally identified by subjects across all ages. Our results demonstrated the girth of differentiated olfactory loss due to normal ageing, which potentially affect overall perception and preferences of odor mixtures with age. PMID:27001718

  4. Assessment of transport parameters in a karst system under various flow periods through extensive analysis of artificial tracer tests

    NASA Astrophysics Data System (ADS)

    Doummar, J.; Margane, A.; Sauter, M.; Geyer, T.

    2012-04-01

    It is primordial to understand the sensibility of a catchment or a spring against contamination to secure a sustainable water resource management in karst aquifers. Artificial tracer tests have proven to be excellent tools for the simulation of contaminant transport within an aquifer before its arrival at a karst spring as they provide information about transit times, dispersivities and therefore insights into the vulnerability of a water body against contamination (Geyer et al. 2007). For this purpose, extensive analysis of artificial tracer tests was undertaken in the following work, in order to acquire conservative transport parameters along fast and slow pathways in a mature karst system under various flow conditions. In the framework of the project "Protection of Jeita Spring" (BGR), about 30 tracer tests were conducted on the catchment area of the Jeita spring in Lebanon (Q= 1 to 20 m3/s) under various flow conditions and with different injection points (dolines, sinkholes, subsurface, and underground channel). Tracer breakthrough curves (TBC) observed at karst springs and in the conduit system were analyzed using the two-region non-equilibrium approach (2NREM) (Toride & van Genuchten 1999). The approach accounts for the skewness in the TBCs long tailings, which cannot be described with one dimensional advective-dispersive transport models (Geyer et al. 2007). Relationships between the modeling parameters estimated from the TBC were established under various flow periods. Rating curves for velocity and discharge show that the flow velocity increases with spring discharge. The calibrated portion of the immobile region in the conduit system is relatively low. Estimated longitudinal dispersivities in the conduit system range between 7 and 10 m in high flow periods and decreases linearly with increasing flow. In low flow periods, this relationship doesn't hold true as longitudinal dispersivities range randomly between 4 and 7 m. The longitudinal dispersivity

  5. Age-related changes in human posture control: Motor coordination tests

    NASA Technical Reports Server (NTRS)

    Peterka, R. J.; Black, F. O.

    1989-01-01

    Postural responses to support surface displacements were measured in 214 normal human subjects ranging in age from 7 to 81 years. Motor tests measured leg muscle Electromyography (EMG) latencies, body sway, and the amplitude and timing of changes in center of pressure displacements in response to sudden forward and backward horizontal translations of the support surface upon which the subjects stood. There were small increases in both EMG latencies and the time to reach the peak amplitude of center of pressure responses with increasing age. The amplitude of center of pressure responses showed little change with age if the amplitude measures were normalized by a factor related to subject height. In general, postural responses to sudden translations showed minimal changes with age, and all age related trends which were identified were small relative to the variability within the population.

  6. Testing the applicability of six macroscopic skeletal aging techniques on a modern Southeast Asian sample.

    PubMed

    Gocha, Timothy P; Ingvoldstad, Megan E; Kolatorowicz, Adam; Cosgriff-Hernandez, Meghan-Tomasita J; Sciulli, Paul W

    2015-04-01

    Most macroscopic skeletal aging techniques used by forensic anthropologists have been developed and tested only on reference material from western populations. This study examined the performance of six aging techniques on a known age sample of 88 Southeast Asian individuals. Methods examined included the Suchey-Brooks method of aging the symphyseal face of the os pubis (Brooks and Suchey, Hum. Evol. 5 (1990) 227), Buckberry and Chamberlain's, Am. J. Phys. Anthropol. 119 (2002) 231 and Osborne et al.'s, J. Forensic Sci. 49 (2004) 1 revisions of the Lovejoy et al., Am. J. Phys. Anthropol. 68 (1985) 15 method of aging the auricular surface of the ilium, İşcan et al.'s, J. Forensic Sci. 29 (1984) 1094, İşcan et al.'s, J. Forensic Sci. 30 (1985) 853 method of aging the sternal end of the fourth rib, and Meindl and Lovejoy's, Am. J. Phys. Anthropol. 68 (1985) 57 methods for aging both lateral-anterior and vault sutures on the cranium. The results of this study indicate that application of aging techniques commonly used in forensic anthropology to individuals identified as Asian, and more specifically Southeast Asian, should not be undertaken injudiciously. Of the six individual methods tested here, the Suchey-Brooks pubic symphysis aging method performs best, though average age estimates were still off by nearly 10 years or greater. Methods for aging the auricular surface perform next best, though the Osborne et al. method works better for individuals below 50 years and the Buckberry and Chamberlain method works better for those above 50 years. Methods for age estimation from the sternal ends of the fourth rib and vault and lateral-anterior cranial sutures perform poorly and are not recommended for use on remains of Southeast Asian ancestry. Combining age estimates from multiple indicators, specifically the pubic symphysis and one auricular surface method, was superior to individual methods. Data and a worked example are provided for calculating the conditional

  7. Age, gender and suicidal ideation following voluntary HIV counseling and testing.

    PubMed

    Schlebusch, Lourens; Govender, Romona Devi

    2012-02-01

    The aim of this study was to determine the prevalence of suicidal ideation in patients who were tested for HIV-infection and whether along with their HIV status, age and gender influenced their risk for suicidal ideation. The sample consisted of 189 patients who attended a voluntary HIV counseling and testing clinic (VCT) at a general state hospital in Durban, South Africa. Their mean age at baseline was 34.2 years, with an age range of between 16-79 years. Seropositivity, age and gender were significantly associated with suicidal ideation. The majority of these patients were in the younger age group, and young males had a 1.8 times higher risk for suicidal ideation than females. Although risk factors for seropositive-related suicidal ideation can be complex and multi-factorial, this study identified a young age and male gender as important high risk factors in the sample studied. It is recommended that all, but especially young male HIV-infected patients seen at a VCT clinic be screened for suicidal ideation and that early intervention to prevent subsequent suicides or suicidal attempts be included in pre- and post-test HIV counseling. PMID:22470307

  8. Sixth Status Report: Testing of Aged Softwood Fiberboard Material for the 9975 Shipping Package

    SciTech Connect

    Daugherty, W.

    2015-03-31

    Samples have been prepared from several 9975 lower fiberboard subassemblies fabricated from softwood fiberboard. Physical, mechanical and thermal properties have been measured following varying periods of conditioning in each of several environments. These tests have been conducted in the same manner as previous testing on cane fiberboard samples. Overall, similar aging trends are observed for softwood and cane fiberboard samples, with a few differences. Some softwood fiberboard properties tend to degrade faster in some environments, while some cane fiberboard properties degrade faster in the two most aggressive environments. As a result, it is premature to assume both materials will age at the same rates, and the preliminary aging models developed for cane fiberboard might not apply to softwood fiberboard. However, it is expected that both cane and softwood fiberboard assemblies will perform satisfactorily in conforming packages stored in a typical KAC storage environment for up to 15 years. Samples from an additional 3 softwood fiberboard assemblies have begun aging during the past year to provide information on the variability of softwood fiberboard behavior. Aging and testing of softwood fiberboard will continue and additional data will be collected to support development of an aging model specific to softwood fiberboard.

  9. Seismic-fragility tests of new and accelerated-aged Class 1E battery cells

    SciTech Connect

    Bonzon, L.L.; Janis, W.J.; Black, D.A.; Paulsen, G.A.

    1987-01-01

    The seismic-fragility response of naturally-aged nuclear station safety-related batteries is of interest for two reasons: (1) to determine actual failure modes and thresholds and (2) to determine the validity of using the electrical capacity of individual cells as an indicator of the potential survivability of a battery given a seismic event. Prior reports in this series discussed the seismic-fragility tests and results for three specific naturally-aged cell types: 12-year old NCX-2250, 10-year old LCU-13, and 10-year old FHC-19. This report focuses on the complementary approach, namely, the seismic-fragility response of accelerated-aged batteries. Of particular interest is the degree to which such approaches accurately reproduce the actual failure modes and thresholds. In these tests the significant aging effects observed, in terms of seismic survivability, were: embrittlement of cell cases, positive bus material and positive plate grids; and excessive sulphation of positive plate active material causing hardening and expansion of positive plates. The IEEE Standard 535 accelerated aging method successfully reproduced seismically significant aging effects in new cells but accelerated grid embrittlement an estimated five years beyond the conditional age of other components.

  10. Aging.

    PubMed

    Park, Dong Choon; Yeo, Seung Geun

    2013-09-01

    Aging is initiated based on genetic and environmental factors that operate from the time of birth of organisms. Aging induces physiological phenomena such as reduction of cell counts, deterioration of tissue proteins, tissue atrophy, a decrease of the metabolic rate, reduction of body fluids, and calcium metabolism abnormalities, with final progression onto pathological aging. Despite the efforts from many researchers, the progression and the mechanisms of aging are not clearly understood yet. Therefore, the authors would like to introduce several theories which have gained attentions among the published theories up to date; genetic program theory, wear-and-tear theory, telomere theory, endocrine theory, DNA damage hypothesis, error catastrophe theory, the rate of living theory, mitochondrial theory, and free radical theory. Although there have been many studies that have tried to prevent aging and prolong life, here we introduce a couple of theories which have been proven more or less; food, exercise, and diet restriction. PMID:24653904

  11. Aging

    PubMed Central

    Park, Dong Choon

    2013-01-01

    Aging is initiated based on genetic and environmental factors that operate from the time of birth of organisms. Aging induces physiological phenomena such as reduction of cell counts, deterioration of tissue proteins, tissue atrophy, a decrease of the metabolic rate, reduction of body fluids, and calcium metabolism abnormalities, with final progression onto pathological aging. Despite the efforts from many researchers, the progression and the mechanisms of aging are not clearly understood yet. Therefore, the authors would like to introduce several theories which have gained attentions among the published theories up to date; genetic program theory, wear-and-tear theory, telomere theory, endocrine theory, DNA damage hypothesis, error catastrophe theory, the rate of living theory, mitochondrial theory, and free radical theory. Although there have been many studies that have tried to prevent aging and prolong life, here we introduce a couple of theories which have been proven more or less; food, exercise, and diet restriction. PMID:24653904

  12. Performance testing of aged hydrogen getters against criteria for interim safe storage of plutonium bearing materials.

    SciTech Connect

    Shepodd, Timothy J.; Nissen, April; Buffleben, George M.

    2006-01-01

    Hydrogen getters were tested for use in storage of plutonium-bearing materials in accordance with DOE's Criteria for Interim Safe Storage of Plutonium Bearing Materials. The hydrogen getter HITOP was aged for 3 months at 70 C and tested under both recombination and hydrogenation conditions at 20 and 70 C; partially saturated and irradiated aged getter samples were also tested. The recombination reaction was found to be very fast and well above the required rate of 45 std. cc H2h. The gettering reaction, which is planned as the backup reaction in this deployment, is slower and may not meet the requirements alone. Pressure drop measurements and {sup 1}H NMR analyses support these conclusions. Although the experimental conditions do not exactly replicate the deployment conditions, the results of our conservative experiments are clear: the aged getter shows sufficient reactivity to maintain hydrogen concentrations below the flammability limit, between the minimum and maximum deployment temperatures, for three months. The flammability risk is further reduced by the removal of oxygen through the recombination reaction. Neither radiation exposure nor thermal aging sufficiently degrades the getter to be a concern. Future testing to evaluate performance for longer aging periods is in progress.

  13. Test-Retest Reliability of the 10-Metre Fast Walk Test and 6-Minute Walk Test in Ambulatory School-Aged Children with Cerebral Palsy

    ERIC Educational Resources Information Center

    Thompson, Patricia; Beath, Tricia; Bell, Jacqueline; Jacobson, Gabrielle; Phair, Tegan; Salbach, Nancy M.; Wright, F. Virginia

    2008-01-01

    Short-term test-retest reliability of the 10-metre fast walk test (10mFWT) and 6-minute walk test (6MWT) was evaluated in 31 ambulatory children with cerebral palsy (CP), with subgroup analyses in Gross Motor Function Classification System (GMFCS) Levels I (n=9), II (n=8), and III (n=14). Sixteen females and 15 males participated, mean age 9 years…

  14. The Stroop Color-Word Test: Influence of Age, Sex, and Education; and Normative Data for a Large Sample Across the Adult Age Range

    ERIC Educational Resources Information Center

    Van der Elst, Wim; Van Boxtel, Martin P. J.; Van Breukelen, Gerard J. P.; Jolles, Jelle

    2006-01-01

    The Stroop Color-Word Test was administered to 1,856 cognitively screened, healthy Dutch-speaking participants aged 24 to 81 years. The effects of age, gender, and education on Stroop test performance were investigated to adequately stratify the normative data. The results showed that especially the speed-dependent Stroop scores (time to complete…

  15. A Testing Platform for Validation of Overhead Conductor Aging Models and Understanding Thermal Limits

    SciTech Connect

    Irminger, Philip; Starke, Michael R; Dimitrovski, Aleksandar D; Young II, Marcus Aaron; Rizy, D Tom; Stovall, John P; Overholt, Philip N

    2014-01-01

    Power system equipment manufacturers and researchers continue to experiment with novel overhead electric conductor designs that support better conductor performance and address congestion issues. To address the technology gap in testing these novel designs, Oak Ridge National Laboratory constructed the Powerline Conductor Accelerated Testing (PCAT) facility to evaluate the performance of novel overhead conductors in an accelerated fashion in a field environment. Additionally, PCAT has the capability to test advanced sensors and measurement methods for accessing overhead conductor performance and condition. Equipped with extensive measurement and monitoring devices, PCAT provides a platform to improve/validate conductor computer models and assess the performance of novel conductors. The PCAT facility and its testing capabilities are described in this paper.

  16. THIRD STATUS REPORT: TESTING OF AGED SOFTWOOD FIBERBOARD MATERIAL FOR THE 9975 SHIPPING PACKAGE

    SciTech Connect

    Daugherty, W.

    2011-12-13

    Samples have been prepared from a 9975 lower fiberboard subassembly fabricated from softwood fiberboard. Physical, mechanical and thermal properties have been measured following varying periods of conditioning in each of several environments. These tests have been conducted in the same manner as previous testing on cane fiberboard samples. Overall, similar aging trends are observed for softwood and cane fiberboard samples, with a few differences. There is no clear trend thus far to indicate one material ages in a manner significantly different from the other material. Some softwood fiberboard properties degrade faster in some environments, while cane fiberboard degrades faster with regards to other properties and environments. Given the limited aging time accumulated to date in the elevated humidity environments, it is recommended that aging and testing of softwood fiberboard continue for another year. Post-conditioning data have been measured on samples from a single softwood fiberboard assembly, and baseline data are also available from a limited number of vendor-provided samples. This provides minimal information on the possible sample-to-sample variation exhibited by softwood fiberboard. Data to date are generally consistent with the range seen in cane fiberboard, but some portions of the data trends are skewed toward the lower end of that range. Further understanding of the variability of softwood fiberboard properties will require testing of additional material.

  17. FOURTH STATUS REPORT: TESTING OF AGED SOFTWOOD FIBERBOARD MATERIAL FOR THE 9975 SHIPPING PACKAGE

    SciTech Connect

    Daugherty, W.

    2013-03-05

    Samples have been prepared from a 9975 lower fiberboard subassembly fabricated from softwood fiberboard. Physical, mechanical and thermal properties have been measured following varying periods of conditioning in each of several environments. These tests have been conducted in the same manner as previous testing on cane fiberboard samples. Overall, similar aging trends are observed for softwood and cane fiberboard samples, with a few differences. Some softwood fiberboard properties tend to degrade faster in elevated humidity environments, while some cane fiberboard properties degrade faster in the hotter dry environments. As a result, it is premature to assume both materials will age at the same rates, and the preliminary aging models developed for cane fiberboard might not apply to softwood fiberboard. However, it is expected that both cane and softwood fiberboard assemblies will perform satisfactorily in conforming packages stored in a typical KAMS environment for up to 15 years. Aging and testing of softwood fiberboard will continue and additional data will be collected. Post-conditioning data have been measured on samples from a single softwood fiberboard assembly, and baseline data are also available from a limited number of vendor-provided samples. This provides minimal information on the possible sample-to-sample variation exhibited by softwood fiberboard. Data to date are generally consistent with the range seen in cane fiberboard, but some portions of the data trends are skewed toward the lower end of that range. Further understanding of the variability of softwood fiberboard properties will require testing of additional material.

  18. Pilot Testing "Okay with Asthma"[TM]: An Online Asthma Intervention for School-Age Children

    ERIC Educational Resources Information Center

    Wyatt, Tami H.; Hauenstein, Emily J.

    2008-01-01

    Asthma is the leading cause of missed school days despite advancements in asthma treatment. This may be, in part, due to a lack of understanding about asthma. "Okay With Asthma"[TM], an online story with psychosocial management strategies for school-age children, was pilot tested to measure its effect on asthma knowledge and attitude. The online…

  19. A Review of Academic Achievement Tests: Recommendations for Age Appropriate Administration

    ERIC Educational Resources Information Center

    Kozloff, Allison Burstein

    2009-01-01

    Comprehensive academic achievement tests are routinely used by school psychologists in psycho-educational assessment batteries to identify learning disabled students. A variety of assessment measures are used across age groups to determine if a discrepancy exists between academic achievement and intellectual functioning; however, among the most…

  20. The Influence of Education and Age on Neurocognitive Test Performance in Alzheimer's Disease and Vascular Dementia

    ERIC Educational Resources Information Center

    DenBesten, Nicholas P.

    2009-01-01

    This research involves an examination of the relationship between education and age on a wide array of neuropsychological test measures among patients diagnosed with Alzheimer's and vascular dementia. The purpose of this study was to investigate the role of education as an attenuating factor to neurocognitive decline in dementia. Although numerous…

  1. Test-Retest Reliability of the Preschool Age Psychiatric Assessment (PAPA)

    ERIC Educational Resources Information Center

    Egger, Helen Link; Erkanli, Alaattin; Keeler, Gordon; Potts, Edward; Walter, Barbara Keith; Angold, Adrian

    2006-01-01

    Objective: To examine the test-retest reliability of a new interviewer-based psychiatric diagnostic measure (the Preschool Age Psychiatric Assessment) for use with parents of preschoolers 2 to 5 years old. Method: A total of 1,073 parents of children attending a large pediatric clinic completed the Child Behavior Checklist 1 1/2-5. For 18 months,…

  2. Who, When, and Where? Age-Related Differences on a New Memory Test

    ERIC Educational Resources Information Center

    Sumida, Catherine A.; Holden, Heather M.; Van Etten, Emily J.; Wagner, Gabrielle M.; Hileman, Jacob D.; Gilbert, Paul E.

    2016-01-01

    Our study examined age-related differences on a new memory test assessing memory for "who," "when," and "where," and associations among these elements. Participants were required to remember a sequence of pictures of different faces paired with different places. Older adults remembered significantly fewer correct…

  3. Reference Data for the Ruff Figural Fluency Test Stratified by Age and Educational Level

    PubMed Central

    Izaks, Gerbrand J.; Joosten, Hanneke; Koerts, Janneke; Gansevoort, Ron T.; Slaets, Joris P.

    2011-01-01

    The Ruff Figural Fluency Test (RFFT) was developed to avoid the difficulties that were encountered in earlier tests of figural fluency. Although the test characteristics of the RFFT seem to be good and it is a valuable addition to neuropsychological assessments, reference data are still scarce. To this aim, we required 2,404 community dwelling persons in Groningen, the Netherlands to perform the RFFT. All 1,651 persons with a complete RFFT and known educational level formed the reference sample. Their age ranged from 35 to 82 years and their educational level from primary school to university grade. Ninety-six percent of the persons were of Western European descent. All tests were analyzed by two independent examiners and subsequently three measures were calculated: number of unique designs, number of perseverative errors and error ratio. The main finding was that performance on the RFFT was dependent on age and educational level. This was not only observed in older persons but also in young and middle-aged persons. Reference data for the three RFFT measures are presented in groups of five years of age ranging from 35–39 years to 75 years or older. PMID:21347325

  4. Long-term aging and loss-of-coolant accident (LOCA) testing of electrical cables

    SciTech Connect

    Nelson, C.F.; Gauthier, G.; Carlin, F.

    1996-10-01

    Experiments were performed to assess the aging degradation and loss-of-coolant accident (LOCA) behavior of electrical cables subjected to long-term aging exposures. Four different cable types were tested in both the U.S. and France: (1) U.S. 2 conductor with ethylene propylene rubber (EPR) insulation and a Hypalon jacket. (2) U.S. 3 conductor with cross-linked polyethylene (XLPE) insulation and a Hypalon jacket. (3) French 3 conductor with EPR insulation and a Hypalon jacket. (4) French coaxial with polyethylene (PE) insulation and a PE jacket. The data represent up to 5 years of simultaneous aging where the cables were exposed to identical aging radiation doses at either 40{degrees}C or 70{degrees}C; however, the dose rate used for the aging irradiation was varied over a wide range (2-100 Gy/hr). Aging was followed by exposure to simulated French LOCA conditions. Several mechanical, electrical, and physical-chemical condition monitoring techniques were used to investigate the degradation behavior of the cables. All the cables, except for the French PE cable, performed acceptably during the aging and LOCA simulations. In general, cable degradation at a given dose was highest for the lowest dose rate, and the amount of degradation decreased as the dose rate was increased.

  5. A comparative test of the investigator as a variable in aging quail

    USGS Publications Warehouse

    Rosene, W.; Fitch, F.

    1956-01-01

    To test the reliability of current techniques, five biologists appraised the ages of 200 quail from a random sample of wings collected during the 1952-53 hunting season in Alabama. Attempt was made to distinguish adults from juveniles, to ascertain the stage of post-nuptial and post-juvenile molts, and to estimate the age of juveniles according to days or weeks. Three 'problem' wings in this sample had molt characteristics somewhat eauallv divided between adult and juvenile classes; two wings called 'questionable' had all molt characteristics except one of either age group. A 3.5 per cent disparity occurred between investigators in their classification of adult and juvenile age groups. This included not only 'problem' and 'questionable' wings, but also 'obvious errors.' Individual differences were greater than 3.5 per cent but cancelled out. This study emphasizes the need of working with large samples of birds of a known age in order to know more concerning molt variations. Until aging techniques can be refined, it is believed that investigators should be fully familiar with existing methods and their weaknesses. Also, it appears important that reports on aging should indicate clearly the techniques used.

  6. Lactulose Hydrogen Breath Test Result Is Associated with Age and Gender

    PubMed Central

    Newberry, Carolyn; Tierney, Ann; Pickett-Blakely, Octavia

    2016-01-01

    Small intestinal bacterial overgrowth (SIBO) is associated with chronic gastrointestinal diseases and structural/functional abnormalities of the gastrointestinal tract. SIBO's association with clinical characteristics is unclear. This study investigates the association between clinical factors and SIBO according to lactulose hydrogen breath test (LHBT) result. Methods. A cross-sectional study in a university-based gastroenterology practice was performed. Data was abstracted from the medical records of subjects undergoing LHBT from 6/1/2009 to 6/1/2013. Logistic regression analysis was performed to determine the association between predictor variables: age, sex, body mass index (BMI), and positive LHBT, the outcome of interest. Results. LHBT was performed in 791 subjects. Fifty-four percent had a positive LHBT. There was no statistically significant difference between the LHBT results according to age or BMI. In females, the likelihood of a positive LHBT increased with age (OR 1.02; 95% CI: 1.01–1.03). In males, the likelihood of a positive LHBT result decreased with age (OR 0.98; 95% CI: 0.97–1.00). Conclusion. There was an association between age, with respect to sex, and a positive LHBT. With increased age in females, the odds of a positive LHBT increased, while, in men, the odds of a positive LHBT decreased with age. PMID:27073800

  7. Lactulose Hydrogen Breath Test Result Is Associated with Age and Gender.

    PubMed

    Newberry, Carolyn; Tierney, Ann; Pickett-Blakely, Octavia

    2016-01-01

    Small intestinal bacterial overgrowth (SIBO) is associated with chronic gastrointestinal diseases and structural/functional abnormalities of the gastrointestinal tract. SIBO's association with clinical characteristics is unclear. This study investigates the association between clinical factors and SIBO according to lactulose hydrogen breath test (LHBT) result. Methods. A cross-sectional study in a university-based gastroenterology practice was performed. Data was abstracted from the medical records of subjects undergoing LHBT from 6/1/2009 to 6/1/2013. Logistic regression analysis was performed to determine the association between predictor variables: age, sex, body mass index (BMI), and positive LHBT, the outcome of interest. Results. LHBT was performed in 791 subjects. Fifty-four percent had a positive LHBT. There was no statistically significant difference between the LHBT results according to age or BMI. In females, the likelihood of a positive LHBT increased with age (OR 1.02; 95% CI: 1.01-1.03). In males, the likelihood of a positive LHBT result decreased with age (OR 0.98; 95% CI: 0.97-1.00). Conclusion. There was an association between age, with respect to sex, and a positive LHBT. With increased age in females, the odds of a positive LHBT increased, while, in men, the odds of a positive LHBT decreased with age. PMID:27073800

  8. Age differences in the Attention Network Test: Evidence from behavior and event-related potentials.

    PubMed

    Williams, Ryan S; Biel, Anna Lena; Wegier, Pete; Lapp, Leann K; Dyson, Benjamin J; Spaniol, Julia

    2016-02-01

    The Attention Network Test (ANT) is widely used to capture group and individual differences in selective attention. Prior behavioral studies with younger and older adults have yielded mixed findings with respect to age differences in three putative attention networks (alerting, orienting, and executive control). To overcome the limitations of behavioral data, the current study combined behavioral and electrophysiological measures. Twenty-four healthy younger adults (aged 18-29years) and 24 healthy older adults (aged 60-76years) completed the ANT while EEG data were recorded. Behaviorally, older adults showed reduced alerting, but did not differ from younger adults in orienting or executive control. Electrophysiological components related to alerting and orienting (P1, N1, and CNV) were similar in both age groups, whereas components related to executive control (N2 and P3) showed age-related differences. Together these results suggest that comparisons of network effects between age groups using behavioral data alone may not offer a complete picture of age differences in selective attention, especially for alerting and executive control networks. PMID:26760449

  9. Extension of viscoplasticity based on overstress to capture the effects of prior aging on the time dependent deformation behavior of a high-temperature polymer: Experiments and modeling

    NASA Astrophysics Data System (ADS)

    McClung, Amber J. W.

    The inelastic deformation behavior of PMR-15 neat resin, a high-temperature thermoset polymer, was investigated at 288° C. The experimental program was designed to explore the influence of strain rate on tensile loading, unloading, and strain recovery behaviors. In addition, the effect of the prior strain rate on the relaxation response of the material, as well as on the creep behavior following strain controlled loading were examined. The material exhibits positive, nonlinear strain rate sensitivity in monotonic loading. Nonlinear, "curved" stress-strain behavior during unloading is observed at all strain rates. The recovery of strain at zero stress is strongly affected by prior strain rate. The prior strain rate also has a profound influence on relaxation behavior. The rest stresses measured at the termination of relaxation tests form the relaxation boundary which resembles a nonlinear stress-strain curve. Likewise, creep response is significantly influenced by prior strain rate. The experimental results suggest that the inelastic behavior of the PMR-15 solid polymer at 288°C can be represented using a unified constitutive model with an overstress dependence of the inelastic rate of deformation. The experimental data were modeled with the Viscoplasticity Based on Overstress (VBO) theory. A systematic procedure for determining model parameters was developed and the model was employed to predict the response of the material under various test histories. Additionally the effects of prior aging at 288° C in argon on the time (rate)-dependent behavior of the PMR-15 polymer were evaluated in a series of strain and load controlled experiments. Based on experimental results, the VBO theory was extended to capture the environmentally induced changes in the material response. Several of the VBO material parameters were expanded as functions of prior aging time. The resulting model was used to predict the high-temperature behavior of the PMR-15 polymer subjected to prior

  10. Unique designs, errors and strategies in the Five-Point Test: The contribution of age, phonemic fluency and visuospatial abilities in Italian children aged 6-11 years.

    PubMed

    Stievano, Paolo; Scalisi, Teresa Gloria

    2016-01-01

    Performances on the Five-Point Test of 161 Italian children aged 6 to 11 years were investigated, along with phonemic fluency, visual-motor integration, visual perception, motor coordination, visuospatial memory, and fluid intelligence. Five-Point Test accuracy was significantly related to phonemic fluency and visual-motor integration, while phonemic fluency was linked to motor coordination. The two fluency measures increased linearly with age, but the developmental progression of Five-Point Test accuracy was less influenced by age. Different age effects were also found on the relationship between fluid intelligence and the two fluency measures. The inspection of qualitative aspects of Five-Point Test performance (errors and strategies) suggested that strategy usage enhanced both productivity and accuracy in children; age-related changes were observed in the relationship between the number of errors and the total number of designs produced. PMID:25495262

  11. OTSEGO COUNTY EXPERIMENTAL PROGRAM FOR TESTING METHODS OF FORMING FARM MANAGEMENT STUDY GROUPS, A PROGRESS REPORT. EXTENSION STUDY, NUMBER 8.

    ERIC Educational Resources Information Center

    LONGEST, JAMES W.; GENGENBACK, WILLIAM H.

    THE MOST FREQUENT METHOD OF GROUP FORMATION FOR INTENSIVE FARM MANAGEMENT PROGRAMS IN NEW YORK STATE HAS BEEN TO COMBINE ALL INTERESTED FARMERS IN LARGE GROUPS AT THE COUNTY EXTENSION HEADQUARTERS. THIS EXPERIMENT WAS SET UP TO STUDY THE EFFECTIVENESS OF TWO METHODS OF FORMING SMALL GROUPS--BY SOCIOMETRIC CHOICE OR SIMILAR CHARACTERISTICS. ALL…

  12. The long-term benefits of genotypic resistance testing in patients with extensive prior antiretroviral therapy: a model-based approach

    PubMed Central

    Yazdanpanah, Y; Vray, M; Meynard, J; Losina, E; Weinstein, MC; Morand-Joubert, L; Goldie, SJ; Hsu, HE; Walensky, RP; Dalban, C; Sax, PE; Girard, PM; Freedberg, KA

    2008-01-01

    Objectives Resistance testing in HIV disease may provide long-term benefits that are not evident from short-term data. Our objectives were to estimate the long-term effectiveness, cost and cost-effectiveness of genotype testing in patients with extensive antiretroviral exposure. Methods We used an HIV simulation model to estimate the long-term effectiveness and cost-effectiveness of genotype testing. Clinical data incorporated into the model were from NARVAL, a randomized trial of resistance testing in patients with extensive antiretroviral exposure, and other randomized trials. Each simulated patient was eligible for up to three sequential regimens of antiretroviral therapy (i.e. two additional regimens beyond the trial-based regimen) using drugs not available at the time of the study, such as lopinavir/ritonavir, darunavir/ritonavir and enfuvirtide. Results In the long term, projected undiscounted life expectancy increased from 132.2 months with clinical judgement alone to 147.9 months with genotype testing. Median survival was estimated at 11.9 years in the resistance testing arm vs 10.4 years in the clinical judgement alone arm. Because of increased survival, the projected lifetime discounted cost of genotype testing was greater than for clinical judgement alone (€313 900 vs €263100; US$399 000 vs US$334 400). Genotype testing cost €69 600 (US$88 500) per quality-adjusted life year gained compared with clinical judgement alone. Conclusions In patients with extensive prior antiretroviral exposure, genotype testing is likely to increase life expectancy in the long term as a result of the increased likelihood of receiving two active new drugs. Genotype testing is associated with cost-effectiveness comparable to that of strategies accepted in patients with advanced HIV disease, such as enfuvirtide use. PMID:17760736

  13. Age-related changes in human vestibulo-ocular reflexes: Sinusoidal rotation and caloric tests

    NASA Technical Reports Server (NTRS)

    Peterka, R. J.; Black, F. O.; Schoenhoff, M. B.

    1989-01-01

    The dynamic response properties of horizontal vestibulo-ocular reflex (VOR) were characterized in 216 human subjects ranging in age from 7 to 81 years. The object of this cross-sectional study was to determine the effects of aging on VOR dynamics, and to identify the distributions of parameters which describe VOR responses to caloric and to sinusoidal rotational stimuli in a putatively normal population. Caloric test parameters showed no consistent trend with age. Rotation test parameters showed declining response amplitude and slightly less compensatory response phase with increasing age. The magnitudes of these changes were not large relative to the variability within the population. The age-related trends in VOR were not consistent with the anatomic changes in the periphery reported by others which showed an increasing rate of peripheral hair cell and nerve fiber loss in subjects over 55 years. The poor correlation between physiological and anatomical data suggest that adaptive mechanisms in the central nervous system are important in maintaining the VOR.

  14. A Meta-Analysis of Extensive Reading Research

    ERIC Educational Resources Information Center

    Nakanishi, Takayuki

    2015-01-01

    The purposes of this study were to investigate the overall effectiveness of extensive reading, whether learners' age impacts learning, and whether the length of time second language learners engage in extensive reading influences test scores. The author conducted a meta-analysis to answer research questions and to identify future research…

  15. Testing an 'aging gene' in long-lived drosophila strains: increased longevity depends on sex and genetic background.

    PubMed

    Spencer, Christine C; Howell, Christine E; Wright, Amber R; Promislow, Daniel E L

    2003-04-01

    Molecular advances of the past decade have led to the discovery of a myriad of 'aging genes' (methuselah, Indy, InR, Chico, superoxide dismutase) that extend Drosophila lifespan by up to 85%. Despite this life extension, these mutants are no longer lived than at least some recently wild-caught strains. Typically, long-lived mutants are identified in relatively short-lived genetic backgrounds, and their effects are rarely tested in genetic backgrounds other than the one in which they were isolated or derived. However, the mutant's high-longevity phenotype may be dependent on interactions with alleles that are common in short-lived laboratory strains. Here we set out to determine whether one particular mutant could extend lifespan in long-lived genetic backgrounds in the fruit fly, Drosophila melanogaster. We measured longevity and resistance to thermal stress in flies that were transgenically altered to overexpress human superoxide dismutase (SOD) in the motorneurones in each of 10 genotypes. Each genotype carried the genetic background from a different naturally long-lived wild-caught Drosophila strain. While SOD increased lifespan on average, the effect was genotype- and sex-specific. Our results indicate that naturally segregating genes interact epistatically with the aging gene superoxide dismutase to modify its ability to extend longevity. This study points to the need to identify mutants that increase longevity not only in the lab strain of origin but also in naturally long-lived genetic backgrounds. PMID:12882325

  16. FIFTH STATUS REPORT: TESTING OF AGED SOFTWOOD FIBERBOARD MATERIAL FOR THE 9975 SHIPPING PACKAGE

    SciTech Connect

    Daugherty, W.; Skidmore, E.; Dunn, K.

    2014-04-15

    Samples have been prepared from a 9975 lower fiberboard subassembly fabricated from softwood fiberboard. Physical, mechanical and thermal properties have been measured following varying periods of conditioning in each of several environments. These tests have been conducted in the same manner as previous testing on cane fiberboard samples. Overall, similar aging trends are observed for softwood and cane fiberboard samples, with a few differences. Some softwood fiberboard properties tend to degrade faster in elevated humidity environments, while some cane fiberboard properties degrade faster in the hotter dry environments. As a result, it is premature to assume both materials will age at the same rates, and the preliminary aging models developed for cane fiberboard might not apply to softwood fiberboard. However, it is expected that both cane and softwood fiberboard assemblies will perform satisfactorily in conforming packages stored in a typical KAC storage environment for up to 15 years. Aging and testing of softwood fiberboard will continue and additional data will be collected. Additional samples will be added to each aging environment, to support development of an aging model specific to softwood fiberboard. Post-conditioning data have been measured on samples from a single softwood fiberboard assembly, and baseline data are also available from a limited number of vendor-provided samples. This provides minimal information on the possible sample-to-sample variation exhibited by softwood fiberboard. Data to date are generally consistent with the range seen in cane fiberboard, but some portions of the data trends are skewed toward the lower end of that range. Two additional softwood fiberboard source packages have been obtained and will begin to provide data on the range of variability of this material.

  17. Testing seismic hazard models with Be-10 exposure ages for precariously balanced rocks

    NASA Astrophysics Data System (ADS)

    Rood, D. H.; Anooshehpoor, R.; Balco, G.; Brune, J.; Brune, R.; Ludwig, L. Grant; Kendrick, K.; Purvance, M.; Saleeby, I.

    2012-04-01

    Currently, the only empirical tool available to test maximum earthquake ground motions spanning timescales of 10 ky-1 My is the use of fragile geologic features, including precariously balanced rocks (PBRs). The ages of PBRs together with their areal distribution and mechanical stability ("fragility") constrain probabilistic seismic hazard analysis (PSHA) over long timescales; pertinent applications include the USGS National Seismic Hazard Maps (NSHM) and tests for ground motion models (e.g., Cybershake). Until recently, age constraints for PBRs were limited to varnish microlamination (VML) dating techniques and sparse cosmogenic nuclide data; however, VML methods yield minimum limiting ages for individual rock surfaces, and the interpretations of cosmogenic nuclide data were ambiguous because they did not account for the exhumation history of the PBRs or the complex shielding of cosmic rays. We have recently published a robust method for the exposure dating of PBRs combining Be-10 profiles, a numerical model, and a three-dimensional model for each PBR constructed using photogrammetry (Balco et al., 2011, Quaternary Geochronology). Here, we use this method to calculate new exposure ages and fragilities for 6 PBRs in southern California (USA) near the San Andreas, San Jacinto, and Elsinore faults at the Lovejoy Buttes, Round Top, Pacifico, Beaumont South, Perris, and Benton Road sites (in addition to the recently published age of 18.7 +/- 2.8 ka for a PBR at the Grass Valley site). We combine our ages and fragilities for each PBR, and use these data to test the USGS 2008 NSHM PGA with 2% in 50 year probability, USGS 2008 PSHA deaggregations, and basic hazard curves from USGS 2002 NSHM data.

  18. Testing seismic hazard models with Be-10 exposure ages for precariously balanced rocks

    NASA Astrophysics Data System (ADS)

    Rood, D. H.; Anooshehpoor, R.; Balco, G.; Biasi, G. P.; Brune, J. N.; Brune, R.; Grant Ludwig, L.; Kendrick, K. J.; Purvance, M.; Saleeby, I.

    2012-12-01

    Currently, the only empirical tool available to test maximum earthquake ground motions spanning timescales of 10 ky-1 My is the use of fragile geologic features, including precariously balanced rocks (PBRs). The ages of PBRs together with their areal distribution and mechanical stability ("fragility") constrain probabilistic seismic hazard analysis (PSHA) over long timescales; pertinent applications include the USGS National Seismic Hazard Maps (NSHM) and tests for ground motion models (e.g., Cybershake). Until recently, age constraints for PBRs were limited to varnish microlamination (VML) dating techniques and sparse cosmogenic nuclide data; however, VML methods yield minimum limiting ages for individual rock surfaces, and the interpretations of cosmogenic nuclide data were ambiguous because they did not account for the exhumation history of the PBRs or the complex shielding of cosmic rays. We have recently published a robust method for the exposure dating of PBRs combining Be-10 profiles, a numerical model, and a three-dimensional shape model for each PBR constructed using photogrammetry (Balco et al., 2011, Quaternary Geochronology). Here, we use our published method to calculate new exposure ages for PBRs at 6 sites in southern California near the San Andreas, San Jacinto, and Elsinore faults, including: Lovejoy Buttes (9 +/- 1 ka), Round Top (35 +/- 1 ka), Pacifico (19 +/- 1 ka, but with a poor fit to data), Beaumont South (17 +/- 2 ka), Perris (24 +/- 2 ka), and Benton Road (40 +/- 1 ka), in addition to the recently published age of 18.5 +/- 2.0 ka for a PBR at the Grass Valley site. We combine our ages and fragilities for each PBR, and use these data to test the USGS 2008 NSHM PGA with 2% in 50 year probability, USGS 2008 PSHA deaggregations, and basic hazard curves from USGS 2002 NSHM data. Precariously balanced rock in southern California

  19. Magnetic resonance imaging and neuropsychological testing in the spectrum of normal aging

    PubMed Central

    Foss, Maria Paula; Diniz, Paula Rejane Beserra; Formigheri, Paulo; Salmon, Carlos Ernesto Garrido; Speciali, José Geraldo; Santos, Antônio Carlos

    2013-01-01

    OBJECTIVE: To understand the relationships between brain structures and function (behavior and cognition) in healthy aging. METHOD: The study group was composed of 56 healthy elderly subjects who underwent neuropsychological assessment and quantitative magnetic resonance imaging. Cluster analysis classified the cohort into two groups, one (cluster 1) in which the magnetic resonance imaging metrics were more preserved (mean age: 66.4 years) and another (cluster 2) with less preserved markers of healthy brain tissue (mean age: 75.4 years). RESULTS: The subjects in cluster 2 (older group) had worse indices of interference in the Stroop test compared with the subjects in cluster 1 (younger group). Therefore, a simple test such as the Stroop test could differentiate groups of younger and older subjects based on magnetic resonance imaging metrics. CONCLUSION: These results are in agreement with the inhibitory control hypotheses regarding cognitive aging and may also be important in the interpretation of studies with other clinical groups, such as patients with dementia and mild cognitive impairment. PMID:24141834

  20. Development and psychometric testing of the active aging scale for Thai adults

    PubMed Central

    Thanakwang, Kattika; Isaramalai, Sang-arun; Hatthakit, Urai

    2014-01-01

    Background Active aging is central to enhancing the quality of life for older adults, but its conceptualization is not often made explicit for Asian elderly people. Little is known about active aging in older Thai adults, and there has been no development of scales to measure the expression of active aging attributes. Purpose The aim of this study was to develop a culturally relevant composite scale of active aging for Thai adults (AAS-Thai) and to evaluate its reliability and validity. Methods Eight steps of scale development were followed: 1) using focus groups and in-depth interviews, 2) gathering input from existing studies, 3) developing preliminary quantitative measures, 4) reviewing for content validity by an expert panel, 5) conducting cognitive interviews, 6) pilot testing, 7) performing a nationwide survey, and 8) testing psychometric properties. In a nationwide survey, 500 subjects were randomly recruited using a stratified sampling technique. Statistical analyses included exploratory factor analysis, item analysis, and measures of internal consistency, concurrent validity, and test–retest reliability. Results Principal component factor analysis with varimax rotation resulted in a final 36-item scale consisting of seven factors of active aging: 1) being self-reliant, 2) being actively engaged with society, 3) developing spiritual wisdom, 4) building up financial security, 5) maintaining a healthy lifestyle, 6) engaging in active learning, and 7) strengthening family ties to ensure care in later life. These factors explained 69% of the total variance. Cronbach’s alpha coefficient for the overall AAS-Thai was 0.95 and varied between 0.81 and 0.91 for the seven subscales. Concurrent validity and test–retest reliability were confirmed. Conclusion The AAS-Thai demonstrated acceptable overall validity and reliability for measuring the multidimensional attributes of active aging in a Thai context. This newly developed instrument is ready for use as a

  1. Knowledge about aging and worry in older adults: Testing the mediating role of intolerance of uncertainty

    PubMed Central

    Nuevo, Roberto; Wetherell, Julie Loebach; Montorio, Ignacio; Ruiz, Miguel A.; Cabrera, Isabel

    2014-01-01

    Objectives This study aims to explore the relationship between knowledge about aging and severity of worry in older adults, and to test the potential mediational role of intolerance of uncertainty. Method The sample was composed of 120 community-dwelling older adults, with a mean of age of 71.0 years (SD = 6.3). Mediational analyses and structural equation modeling were used to analyze and compare different models. Results Greater knowledge about aging was negatively related to both intolerance of uncertainty and worry, and its effect on worry was partially mediated by intolerance of uncertainty. The mediational model obtained an excellent fit to the data (i.e. Goodness of fit index (GFI) = 0.995) and clearly had a better fit than alternative models. Conclusion These results suggest that a good knowledge of the aging process could help decrease aversive uncertainty and thus reduce the level of worry among older adults. Thus, educational programs to increase knowledge about aging could serve as one preventive strategy for anxiety in old age. PMID:19197699

  2. Evaluation of oxidative behavior of polyolefin geosynthetics utilizing accelerated aging tests based on temperature and pressure

    NASA Astrophysics Data System (ADS)

    Li, Mengjia

    Polyolefin geosynthetics are susceptible to oxidation, which eventually leads to the reduction in their engineering properties. In the application of polyolefin geosynthetics, a major issue is an estimate of the materials durability (i.e. service lifetime) under various aging conditions. Antioxidant packages are added to the polyolefin products to extend the induction time, during which antioxidants are gradually depleted and polymer oxidation reactions are prevented. In this PhD study, an improved laboratory accelerating aging method under elevated and high pressure environments was applied to evaluate the combined effect of temperature and pressure on the depletion of the antioxidants and the oxidation of polymers. Four types of commercial polyolefn geosynthetic materials selected for aging tests included HDPE geogrid, polypropylene woven and nonwoven geotextiles. A total of 33 different temperature/pressure aging conditions were used, with the incubation duration up to 24 months. The applied oven temperature ranged from 35°C to 105°C and the partial oxygen pressure ranged from 0.005 MPa to 6.3 MPa. Using the Oxidative Induction Time (OIT) test, the antioxidant depletion, which is correlated to the decrease of the OIT value, was found to follow apparent first-order decay. The OIT data also showed that, the antioxidant depletion rate increased with temperature according to the Arrhenius equation, while under constant temperatures, the rate increased exponentially with the partial pressure of oxygen. A modified Arrhenius model was developed to fit the antioxidant depletion rate as a function of temperature and pressure and to predict the antioxidant lifetime under various field conditions. This study has developed new temperature/pressure incubation aging test method with lifetime prediction models. Using this new technique, the antioxidant lifetime prediction results are close to regular temperature aging data while the aging duration can be reduced considerably

  3. Study on the thermal deactivation of motorcycle catalytic converters by laboratory aging tests.

    PubMed

    Chen, Yi-Chi; Chen, Lu-Yen; Yu, Yi-Hsien; Jeng, Fu-Tien

    2010-03-01

    Catalytic converters are used to curb exhaust pollution from motorcycles in Taiwan. A number of factors, including the length of time the converter is used for and driving conditions, affect the catalysts' properties during periods of use. The goal of this study is to resolve the thermal deactivation mechanism of motorcycle catalytic converters. Fresh catalysts were treated under different aging conditions by laboratory-scale aging tests to simulate the operation conditions of motorcycle catalytic converters. The aged catalysts were characterized by analytical techniques in order to provide information for investigating deactivation phenomena. The time-dependent data of specific surface areas were subsequently used to construct kinetics of sintering at the specific temperature. According to the analytical results of the catalysts' properties, the increase in aging temperature causes an increase in pore size of the catalysts and a decrease in the specific surface area. The aged catalysts all exhibited lower performances than the fresh ones. The reduction in catalytic activity is consistent with the reduction in the loss of specific surface area. The finding of catalytic properties' dependence on temperature is consistent with the thermally activated theory. In contrast, the effect of the aging time on the specific surface area was only significant during the initial few hours. The high correlation between specific surface areas measured by the Brunauer-Emmett-Teller (BET) method and predicted by the constructed model verifies that the prediction models can predict the sintering rate reasonably under the aging conditions discussed in this study. As compared to automobile catalytic converters, the differences of structures and aging conditions are made less obvious by the deactivation phenomena of motorcycles. PMID:20426275

  4. Adapting a receptive vocabulary test for preschool-aged Greek-speaking children

    PubMed Central

    Okalidou, Areti; Syrika, Asimina; Beckman, Mary E.; Edwards, Jan R.

    2010-01-01

    Introduction Receptive vocabulary is an important measure for language evaluations (e.g. Bornstein & Haynes, 1998; Metsala, 1999; Nation & Snowling, 1997). Therefore, norm-referenced receptive vocabulary tests are widely used in several languages (e.g. Brownell, 2000; Dunn, Dunn, Whetton & Burley, 1997). However, a receptive vocabulary test has not yet been normed for Modern Greek. Aims The purposes of this study were to adapt an American English vocabulary test, the Receptive One-Word Picture Vocabulary Test-II (ROWPVT-II) for Modern Greek for use with Greek-speaking preschool children. Methods & Procedures The list of 170 English words on the ROWPVT-II was adapted by a) developing two lists (list A and list B) of Greek words that would match either the target English word or another concept corresponding to one of the pictured objects in the 4-picture array and b) determining a developmental order for the chosen Greek words for preschool-aged children. For the first task, adult word frequency measures were used to select the words for the Greek wordlist. For the second task, 427 children, 225 boys and 202 girls, ranging in age from 2;0 years though 5;11 years, were recruited from urban and suburban areas of Greece. A pilot study of the two word lists was performed with the aim of comparing an equal number of list A and list B responses for each age group and deriving a new developmental list order. Outcomes & Results The relative difficulty of each Greek word item, i.e. its accuracy score, was calculated by taking the average proportion of correct responses across ages for that word. Subsequently, the word accuracy scores in the two lists were compared via regression analysis which yielded a highly significant relationship (R2 = 0.97; p<0.0001) and a few outlier pairs (via residuals). Further analysis used the original relative ranking order along with the derived ranking order from the average accuracy scores of the two lists, in order to determine which word

  5. 78 FR 5430 - Extension of Approval Period for Certain Tests Used in the National Reporting System for Adult...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-25

    ... Education (NRS regulations) (73 FR 2306). The NRS regulations established the process that the Secretary... submit tests for review under the NRS regulations (73 FR 20616) (April 2008 notice). On February 2, 2010... determined to be suitable for use in the NRS (75 FR 5303). The Secretary determined tests and test forms...

  6. Age-related changes in human posture control: Sensory organization tests

    NASA Technical Reports Server (NTRS)

    Peterka, R. J.; Black, F. O.

    1989-01-01

    Postural control was measured in 214 human subjects ranging in age from 7 to 81 years. Sensory organization tests measured the magnitude of anterior-posterior body sway during six 21 s trials in which visual and somatosensory orientation cues were altered (by rotating the visual surround and support surface in proportion to the subject's sway) or vision eliminated (eyes closed) in various combinations. No age-related increase in postural sway was found for subjects standing on a fixed support surface with eyes open or closed. However, age-related increases in sway were found for conditions involving altered visual or somatosensory cues. Subjects older than about 55 years showed the largest sway increases. Subjects younger than about 15 years were also sensitive to alteration of sensory cues. On average, the older subjects were more affected by altered visual cues whereas younger subjects had more difficulty with altered somatosensory cues.

  7. Predicting Curriculum and Test Performance at Age 11 Years from Pupil Background, Baseline Skills and Phonological Awareness at Age 5 Years

    ERIC Educational Resources Information Center

    Savage, Robert; Carless, Sue; Ferraro, Vittoria

    2007-01-01

    Background: Phonological awareness tests are amongst the best predictors of literacy and predict outcomes of Key Stage 1 assessment of the National Curriculum in England at age 7. However, it is unknown whether their ability to predict National Curricular outcomes extends to Key Stage 2 assessments given at age 11, or also whether the predictive…

  8. Aging and loss-of-coolant accident (LOCA) testing of electrical connections

    SciTech Connect

    Nelson, C.F.

    1998-01-01

    This report presents the results of an experimental program to determine the aging and loss-of-coolant accident (LOCA) behavior of electrical connections in order to obtain an initial scoping of their performance. Ten types of connections commonly used in nuclear power plants were tested. These included 3 types of conduit seals, 2 types of cable-to-device connectors, 3 types of cable-to-cable connectors, and 2 types of in-line splices. The connections were aged for 6 months under simultaneous thermal (99 C) and radiation (46 Gy/hr) conditions. A simulated LOCA consisting of sequential high dose-rate irradiation (3 kGy/hr) and high-temperature steam exposures followed the aging. Connection functionality was monitored using insulation resistance measurements during the aging and LOCA exposures. Because only 5 of the 10 connection types passed a post-LOCA, submerged dielectric withstand test, further detailed investigation of electrical connections and the effects of cable jacket integrity on the cable-connection system is warranted.

  9. Stellite 6 Friction Changes Due to Aging and In-Service Testing

    SciTech Connect

    Watkins, John Clifford; DeWall, Kevin George

    2001-07-01

    For the past several years, researchers at the Idaho National Engineering and Environmental Laboratory, under the sponsorship of the U.S. Nuclear Regulatory Commission, have been investigating the ability of motor-operated valves to close or open when subjected to design basis flow and pressure loads. Part of this research addresses the friction that occurs at the interface between the valve disc and the valve body seats during operation of a gate valve. In most gate valves, these surfaces are hardfaced with Stellite 6, a cobalt-based alloy. The nuclear industry has developed methods to analytically predict the thrust needed to operate these valves at specific pressure conditions. To produce accurate valve thrust predictions; the analyst must have a reasonably accurate, though conservative, estimate of the coefficient of friction at the disc-to-seat interface. One of the questions that remains to be answered is whether, and to what extent, aging of the disc and seat surfaces affects the disc-to-seat coefficient of friction. Specifically, does the accumulation of a surface film due to aging of these surfaces increase the coefficient of friction and if so, how much? This paper presents results of specimen tests addressing this issue with emphasis on the following: • The change in the friction coefficient of Stellite 6 as it ages and whether the friction reaches a plateau. • The effect periodic gate valve cycling due to in-service testing has on the friction coefficient. • The results of an independent review of the test methods, processes, and the results of the research to date. • The status of ongoing aging and friction testing.

  10. Mechanical Testing of TR-55 Rubber Thermally Aged Under Tensile Strain

    SciTech Connect

    Small IV, W; Alviso, C T; Wilson, T S; Chinn, S C; Maxwell, R S

    2009-03-10

    TR-55 rubber specimens were previously subjected to an aging process consisting of the application of a tensile strain of approximately 67%, 100%, 133%, or 167% elongation for 4, 8, 12, or 16 h at either 250 C or room temperature. Control specimens at the same temperatures/durations were not subjected to tensile strain. The specimens were allowed to recover at room temperature without external stimuli for over 100 days before tensile testing. A single dog bone was cut from each specimen and a stress-strain curve was obtained. The elastic modulus of each specimen was calculated. Specimens aged under tensile strain exhibited rubber-like behavior dependent on the aging elongation and duration. This behavior was not evident in the unstrained controls. For the unstrained controls, exposure to 250 C resulted in an increase in modulus relative to the unheated material independent of the heating duration. The tensile strain applied during the aging process caused a reduction in modulus relative to the controls; lower moduli were observed for the shorter aging durations. Slippage of the specimens in the grips prevented determination of ultimate strength, as all specimens either slipped completely out of the grip before failure or failed at the original grip edge after slipping.

  11. Age-of-acquisition effects in reading aloud: tests of cumulative frequency and frequency trajectory.

    PubMed

    Zevin, Jason D; Seidenberg, Mark S

    2004-01-01

    Several studies have reported that the age at which a word is learned affects skilled reading. This age-of-acquisition effect is potentially important for theories of reading and learning. The effect has been difficult to pin down, however, because the age at which a word is learned is correlated with many other lexical properties. Zevin and Seidenberg (2002) analyzed these phenomena, using connectionist models that distinguished between cumulative frequency (the total number of times a word is experienced) and frequency trajectory (the distribution of these experiences over time). The models prompted a reevaluation of the empirical literature on this topic. The present research tested and confirmed three behavioral predictions derived from these models. First, cumulative frequency has an impact on skilled word naming, more so than standard measures of frequency derived from such norms as those of Kucera and Francis (1967). Second, frequency trajectory affects age of acquisition: The timing of exposure to words affects how rapidly they are learned. However, frequency trajectory does not affect skilled reading aloud, because the consistencies in mapping between spelling and sound eventually wash out the effects of early differences in frequency of exposure. Thus, in skilled performance, the timing of exposure to words is less important than the amount of exposure. The results clarify the conditions under which age-dependent learning effects occur in reading aloud. PMID:15078042

  12. PBX 9404 detonation copper cylinder tests: a comparison of new and aged material

    SciTech Connect

    Hill, Larry G; Mier, Robert; Briggs, Matthew E

    2009-01-01

    We present detonation copper cylinder test results on aged PBX 9404 (94 wt% HMX, 3 wt% CEF, 2.9 wt% NC, 0.1 wt% DPA) explosive. The charges were newly pressed from 37.5 year-old molding powder. We compare these results to equivalent data performed on the same lot when it was 3.5 years old. Comparison of the detonation energy inferred from detonation speed to that inferred from wall motion suggests that the HMX energy is unchanged but the NC energy has decreased to {approx}25% of its original value. The degradation of explosives and their binders is a subject of continual interest. Secondary explosives such as HMX are sufficiently stable near room temperature that they do not measurably degrade over a period of at least several decades. For formulated systems the bigger concern is binder degradation, for which the three main issues are strength, initiation safety, and (if the binder is energetic) energy content. In this paper we examine the detonation energy of new and aged PBX 9404 (94 wt% HMX, 3 wt% tris-{beta} chloroethylphosphate (CEF), 2.9 wt% nitrocellulose (NC), 0.1 wt% diphenylamine (DPA) [1, 2]), measured via the detonation copper cylinder test. In 1959, two independent PBX 9404 accidents [3] raised serious concerns about the safety of the formulation. Over about a decade's time, Los Alamos pursued a safer, energetically equivalent replacement, which ultimately became PBX 9501. In order to accurately compare the performance of the PBX 9404 and PBX 9501 formulations, W. Campbell and R. Engelke (C & E) developed a stringent cylinder test protocol that they called the Los Alamos Precision Cylinder Test [4]. The present aging study is possible because excellent PBX 9404 data from those qualification tests endures.

  13. Effects of Age, Exercise Duration, and Test Conditions on Heart Rate Variability in Young Endurance Horses.

    PubMed

    Younes, Mohamed; Robert, Céline; Barrey, Eric; Cottin, François

    2016-01-01

    Although cardiac recovery is an important criterion for ranking horses in endurance competitions, heart rate variability (HRV) has hardly ever been studied in the context of this equestrian discipline. In the present study, we sought to determine whether HRV is affected by parameters such as age, exercise duration and test site. Accordingly, HRV might be used to select endurance horses with the fastest cardiac recovery. The main objective of the present study was to determine the effects of age, exercise duration, and test site on HRV variables at rest and during exercise and recovery in young Arabian endurance horses. Over a 3-year period, 77 young Arabian horses aged 4-6 years performed one or more exercise tests (consisting of a warm-up, cantering at 22 km.h(-1)and a final 500 m gallop at full speed) at four different sites. Beat-to-beat RR intervals were continuously recorded and then analyzed (using a time-frequency approach) to determine the instantaneous HRV components before, during and after the test. At rest, the root-mean-square of successive differences in RR intervals (RMSSD) was higher in the 4-year-olds (54.4 ± 14.5 ms) than in the 5-or 6-year-olds (44.9 ± 15.5 and 49.1 ± 11.7 ms, respectively). During the first 15 min of exercise (period T), the heart rate (HR) and RMSSD decreased with age. In 6-year-olds, RMSSD decreased as the exercise duration increased (T: 3.0 ± 1.4 vs. 2T: 3.6 ± 2.2 vs. 3T: 2.8 ± 1.0). During recovery, RMSSD was negatively correlated with the cardiac recovery time (CRT) and the recovery heart rate (RHR; R = -0.56 and -0.53, respectively; p < 0.05). At rest and during exercise and recovery, RMSSD and several HRV variables differed significantly as a function of the test conditions. HRV in endurance horses appears to be strongly influenced by age and environmental factors (such as ambient temperature, ambient humidity, and track quality). Nevertheless, RMSSD can be used to select endurance horses with the fastest cardiac

  14. Effects of Age, Exercise Duration, and Test Conditions on Heart Rate Variability in Young Endurance Horses

    PubMed Central

    Younes, Mohamed; Robert, Céline; Barrey, Eric; Cottin, François

    2016-01-01

    Although cardiac recovery is an important criterion for ranking horses in endurance competitions, heart rate variability (HRV) has hardly ever been studied in the context of this equestrian discipline. In the present study, we sought to determine whether HRV is affected by parameters such as age, exercise duration and test site. Accordingly, HRV might be used to select endurance horses with the fastest cardiac recovery. The main objective of the present study was to determine the effects of age, exercise duration, and test site on HRV variables at rest and during exercise and recovery in young Arabian endurance horses. Over a 3-year period, 77 young Arabian horses aged 4–6 years performed one or more exercise tests (consisting of a warm-up, cantering at 22 km.h−1and a final 500 m gallop at full speed) at four different sites. Beat-to-beat RR intervals were continuously recorded and then analyzed (using a time-frequency approach) to determine the instantaneous HRV components before, during and after the test. At rest, the root-mean-square of successive differences in RR intervals (RMSSD) was higher in the 4-year-olds (54.4 ± 14.5 ms) than in the 5-or 6-year-olds (44.9 ± 15.5 and 49.1 ± 11.7 ms, respectively). During the first 15 min of exercise (period T), the heart rate (HR) and RMSSD decreased with age. In 6-year-olds, RMSSD decreased as the exercise duration increased (T: 3.0 ± 1.4 vs. 2T: 3.6 ± 2.2 vs. 3T: 2.8 ± 1.0). During recovery, RMSSD was negatively correlated with the cardiac recovery time (CRT) and the recovery heart rate (RHR; R = −0.56 and −0.53, respectively; p < 0.05). At rest and during exercise and recovery, RMSSD and several HRV variables differed significantly as a function of the test conditions. HRV in endurance horses appears to be strongly influenced by age and environmental factors (such as ambient temperature, ambient humidity, and track quality). Nevertheless, RMSSD can be used to select endurance horses with the fastest

  15. Results of Aging Tests of Vendor-Produced Blended Feed Simulant

    SciTech Connect

    Russell, Renee L.; Buchmiller, William C.; Cantrell, Kirk J.; Peterson, Reid A.; Rinehart, Donald E.

    2009-04-21

    The Hanford Tank Waste Treatment and Immobilization Plant (WTP) is procuring through Pacific Northwest National Laboratory (PNNL) a minimum of five 3,500 gallon batches of waste simulant for Phase 1 testing in the Pretreatment Engineering Platform (PEP). To make sure that the quality of the simulant is acceptable, the production method was scaled up starting from laboratory-prepared simulant through 15-gallon vendor prepared simulant and 250-gallon vendor prepared simulant before embarking on the production of the 3500-gallon simulant batch by the vendor. The 3500-gallon PEP simulant batches were packaged in 250-gallon high molecular weight polyethylene totes at NOAH Technologies. The simulant was stored in an environmentally controlled environment at NOAH Technologies within their warehouse before blending or shipping. For the 15-gallon, 250-gallon, and 3500-gallon batch 0, the simulant was shipped in ambient temperature trucks with shipment requiring nominally 3 days. The 3500-gallon batch 1 traveled in a 70-75°F temperature controlled truck. Typically the simulant was uploaded in a PEP receiving tank within 24-hours of receipt. The first uploading required longer with it stored outside. Physical and chemical characterization of the 250-gallon batch was necessary to determine the effect of aging on the simulant in transit from the vendor and in storage before its use in the PEP. Therefore, aging tests were conducted on the 250-gallon batch of the vendor-produced PEP blended feed simulant to identify and determine any changes to the physical characteristics of the simulant when in storage. The supernate was also chemically characterized. Four aging scenarios for the vendor-produced blended simulant were studied: 1) stored outside in a 250-gallon tote, 2) stored inside in a gallon plastic bottle, 3) stored inside in a well mixed 5-L tank, and 4) subject to extended temperature cycling under summer temperature conditions in a gallon plastic bottle. The following

  16. Testing Left-Right extensions of the standard model of electroweak interactions with double-beta decay and LHC measurements

    NASA Astrophysics Data System (ADS)

    Civitarese, O.; Suhonen, J.; Zuber, K.

    2015-07-01

    The minimal extension of the standard model of electroweak interactions allows for massive neutrinos, a massive right-handed boson WR, and a left-right mixing angle ζ. While an estimate of the light (electron) neutrino can be extracted from the non-observation of the neutrinoless double beta decay, the limits on the mixing angle and the mass of the righthanded (RH) boson may be extracted from a combined analysis of the double beta decay measurements (GERDA, EXO-200 and KamLAND-Zen collaborations) and ATLAS data on the two-jets two-leptons signals following the excitation of a virtual RH boson mediated by a heavy-mass neutrino. In this work we shall compare results of both types of experiments, and show that the estimates are not in tension.

  17. Clean fog flashover tests on 138-kV nonceramic line post insulators before and after artificial aging. Final report

    SciTech Connect

    Schneider, H.M.; Guidi, W.W.; Howes, D.R.

    1992-10-01

    This report describes research conducted to determine the contamination performance of {sup 138} kV transmission line insulators utilized by Florida Power and Light Co. Although test results for both ceramic and nonceramic insulators are reported, emphasis is placed on the performance of nonceramic line posts before and after artificial aging. Since it was not possible to obtain nonceramic insulators that were aged in the same environment and for the same amount of time, there was a need to develop an accelerated aging chamber in order to age these insulators artificially. The aging cycle for these tests is designed to represent the severe coastal climate of Florida. Aging is judged by physical observations, leakage current analysis during aging, analytical material measurements and contamination flashover voltage. Flashover performance is evaluated as a function of contamination severity as determined by equivalent salt deposit density (ESDD). Radio interference (RI), television interference (TVI) and audible noise (AN), during contamination flashover tests, are also described.

  18. Clean fog flashover tests on 138-kV nonceramic line post insulators before and after artificial aging

    SciTech Connect

    Schneider, H.M.; Guidi, W.W.; Howes, D.R. . High Voltage Transmission Research Center)

    1992-10-01

    This report describes research conducted to determine the contamination performance of [sup 138] kV transmission line insulators utilized by Florida Power and Light Co. Although test results for both ceramic and nonceramic insulators are reported, emphasis is placed on the performance of nonceramic line posts before and after artificial aging. Since it was not possible to obtain nonceramic insulators that were aged in the same environment and for the same amount of time, there was a need to develop an accelerated aging chamber in order to age these insulators artificially. The aging cycle for these tests is designed to represent the severe coastal climate of Florida. Aging is judged by physical observations, leakage current analysis during aging, analytical material measurements and contamination flashover voltage. Flashover performance is evaluated as a function of contamination severity as determined by equivalent salt deposit density (ESDD). Radio interference (RI), television interference (TVI) and audible noise (AN), during contamination flashover tests, are also described.

  19. Mechanical correction of dynamometer moment for the effects of segment motion during isometric knee-extension tests.

    PubMed

    Tsaopoulos, Dimitrios E; Baltzopoulos, Vasilios; Richards, Paula J; Maganaris, Constantinos N

    2011-07-01

    The purpose of this study was to determine the effect of dynamometer and joint axis misalignment on measured isometric knee-extension moments using inverse dynamics based on the actual joint kinematic information derived from the real-time X-ray video and to compare the errors when the moments were calculated using measurements from external anatomical surface markers or obtained from the isokinetic dynamometer. Six healthy males participated in this study. They performed isometric contractions at 90° and 20° of knee flexion, gradually increasing to maximum effort. For the calculation of the actual knee-joint moment and the joint moment relative to the knee-joint center, determined using the external marker, two free body diagrams were used of the Cybex arm and the lower leg segment system. In the first free body diagram, the mean center of the circular profiles of the femoral epicondyles was used as the knee-joint center, whereas in the second diagram, the joint center was assumed to coincide with the external marker. Then, the calculated knee-joint moments were compared with those measured by the dynamometer. The results indicate that 1) the actual knee-joint moment was different from the dynamometer recorded moment (difference ranged between 1.9% and 4.3%) and the moment calculated using the skin marker (difference ranged between 2.5% and 3%), and 2) during isometric knee extension, the internal knee angle changed significantly from rest to the maximum contraction state by about 19°. Therefore, these differences cannot be neglected if the moment-knee-joint angle relationship or the muscle mechanical properties, such as length-tension relationship, need to be determined. PMID:21474701

  20. 4-Second Exercise Test: Reference Values for Ages 18–81 Years

    PubMed Central

    Araújo, Claudio Gil; de Castro, Claudia Lucia Barros; Franca, João Felipe; Ramos, Plínio Santos

    2015-01-01

    Background Physiological reflexes modulated primarily by the vagus nerve allow the heart to decelerate and accelerate rapidly after a deep inspiration followed by rapid movement of the limbs. This is the physiological and pharmacologically validated basis for the 4-s exercise test (4sET) used to assess the vagal modulation of cardiac chronotropism. Objective To present reference data for 4sET in healthy adults. Methods After applying strict clinical inclusion/exclusion criteria, 1,605 healthy adults (61% men) aged between 18 and 81 years subjected to 4sET were evaluated between 1994 and 2014. Using 4sET, the cardiac vagal index (CVI) was obtained by calculating the ratio between the duration of two RR intervals in the electrocardiogram: 1) after a 4-s rapid and deep breath and immediately before pedaling and 2) at the end of a rapid and resistance-free 4-s pedaling exercise. Results CVI varied inversely with age (r = -0.33, p < 0.01), and the intercepts and slopes of the linear regressions between CVI and age were similar for men and women (p > 0.05). Considering the heteroscedasticity and the asymmetry of the distribution of the CVI values according to age, we chose to express the reference values in percentiles for eight age groups (years): 18–30, 31–40, 41–45, 46–50, 51–55, 56–60, 61–65, and 66+, obtaining progressively lower median CVI values ranging from 1.63 to 1.24. Conclusion The availability of CVI percentiles for different age groups should promote the clinical use of 4sET, which is a simple and safe procedure for the evaluation of vagal modulation of cardiac chronotropism. PMID:25830712

  1. Investigation Of North Anatolian Fault In The Sea Of Marmara: Fault Geometry, The Cumulative Extension, Age Modeling In Çinarcik Basin Using Multi Channel Seismic Reflection Data

    NASA Astrophysics Data System (ADS)

    Atgın, Orhan; Çifçi, Günay; Soelien, Christopher; Seeber, Leonardo; Steckler, Michael; Shillington, Donna; Kurt, Hülya; Dondurur, Derman; Okay, Seda; Gürçay, Savaş; Sarıtaş, Hakan; Mert Küçük, H.; Barın, Burcu

    2013-04-01

    Marmara Sea is a limelight area for investigations due to its tectonic structure and remarkable seismic activity of North Anatolian Fault Zone (NAFZ). As NAFZ separates into 3 branches in the Marmara Sea, it has a complicated tectonic structure which gives rise to debates among researchers. Çınarcık Basin, which is close to Istanbul and very important for its tectonic activity is studied in this thesis. Two different multichannel seismic reflection data were used in this thesis. First data were acquired in 2008 in the frame of TAMAM (Turkish American Multichannel Project) and second data were in 2010 in the frame of TAMAM-2 (PirMarmara) onboard R/V K.Piri Reis. Also high resolution multibeam data were used which is provided by French Marine Institute IFREMER. In the scope of TAMAM project total 3000 km high resolution multi channel data were collected. 3000 km of multichannel seismic reflection profiles were collected in 2008 and 2010 using 72, 111, and 240 channels of streamer with a 6.25 m group interval. The generator-injector airgun was fired every 12.5 or 18.75 m and the resulting MCS data has 10-230 Hz frequency band. In this study, a detailed fault map of the basin is created and the fault on the southern slope of the basin which is interpreted by many researchers in many publications was investigated. And there is no evidence that such a fault exists on the southern part of the basin. With the multichannel seismic reflection data seismic stratigrafic interpretations of the basin deposits were done. The yearly cumulative north-south extension of the basin was calculated by making some calculations on the most active part of the faulting in the basin. In addition, the tilt angles of parallel tilted sediments were calculated and correlated with global sea level changes to calculate ages of the deposits in the basin. Keywords: NAFZ, multi channel seismic reflection, Çınarcık Basin

  2. Correlation of Chemical and Physical Test Data For the Environment Ageing of Coflon (PVDF). Revised

    NASA Technical Reports Server (NTRS)

    Morgan, G. J.; Campion, R. P.

    1997-01-01

    This report aims to identify correlations between mechanical property changes and chemical/morphological structure changes for Coflon. It is intended both to illustrate the overall methodology and to indicate the testing that needs to be undertaken in order to obtain correlations. Many fluid exposures have now been carried out on Coflon during the project and many data generated as a result. The report summarises the changes observed in mechanical and physical properties and relates these as well as possible to the chemistry thought to be occurring during ageing. For this purpose, data have been collated from already-issued MERL and TRI technical and progress reports. Most of the mechanical testing of aged testpieces has been performed soon after the completion of the exposure; however, there is of necessity a delay in obtaining chemical analysis of the same testpieces, so that more physical than chemical data are shown. Three fluids have so far caused measurable deterioration of Coflon, these being: methanol (Fluid A), a methanol and amine mixture (Fluid G), and a mixture of methane, carbon dioxide gas and hydrogen sulphide gas plus aqueous amine (Fluid F). Only the effects of these fluids will be dealt with in any detail in this report, although other fluids are assessed to give relevant background information. Relevant test data collated here include: tensile modulus and related properties, mode of sample failure at break, fracture toughness, fatigue crack growth rate and resistance, stress relaxation rate, permeation coefficients, % crystallinity and molecular weight distributions together with changes in fluorine levels, and other observations where appropriate. However, not all of these were obtained for every ageing condition. Because of the wide range of tests employed, and the different ways in which their results are obtained, the following section has been included to serve as a background for making comparisons.

  3. Biomechanics of the Human Posterior Sclera: Age- and Glaucoma-Related Changes Measured Using Inflation Testing

    PubMed Central

    Coudrillier, Baptiste; Tian, Jing; Alexander, Stephen; Myers, Kristin M.; Quigley, Harry A.; Nguyen, Thao D.

    2012-01-01

    Purpose. The objective of this study was to measure the biomechanical response of the human posterior sclera in vitro and to estimate the effects of age and glaucoma. Methods. Scleral specimens from 22 donors with no history of glaucoma and 11 donors with a history of glaucoma were excised 3 mm posterior to the equator and affixed to an inflation chamber. Optic nerve cross-sections were graded to determine the presence of axon loss. The time-dependent inflation response was measured in a series of pressure-controlled load–unload tests to 30 mm Hg and creep tests to 15 and 30 mm Hg. Circumferential and meridional strains were computed from the digital image correlation displacements, and midposterior stresses were determined from pressure and deformed geometry. Results. Among normal specimens, older age was predictive of a stiffer response and a thinner sclera. In the age group 75 to 93, diagnosed glaucoma eyes with axon damage were thicker than normal eyes. Both damaged and undamaged glaucoma eyes had a different strain response in the peripapillary sclera characterized by a stiffer meridional response. Undamaged glaucoma eyes had slower circumferential creep rates in the peripapillary sclera than normal eyes. Glaucoma eyes were not different from normal eyes in stresses and strains in the midposterior sclera. Conclusions. The observed differences in the biomechanical response of normal and glaucoma sclera may represent baseline properties that contribute to axon damage, or may be characteristics that result from glaucomatous disease. PMID:22395883

  4. The Effects of Aging, Malingering, and Traumatic Brain Injury on Computerized Trail-Making Test Performance

    PubMed Central

    Woods, David L.; Wyma, John M.; Herron, Timothy J.; Yund, E. William

    2015-01-01

    The trail making test (TMT) is widely used to assess speed of processing and executive function. However, normative data sets gathered at different sites show significant inconsistencies. Here, we describe a computerized version of the TMT (C-TMT) that increases the precision and replicability of the TMT by permitting a segment-by-segment analysis of performance and separate analyses of dwell-time, move-time, and error time. Experiment 1 examined 165 subjects of various ages and found that completion times on both the C-TMT-A (where subjects connect successively numbered circles) and the C-TMT-B (where subjects connect circles containing alternating letters and numbers) were strongly influenced by age. Experiment 2 examined 50 subjects who underwent three test sessions. The results of the first test session were well fit by the normative data gathered in Experiment 1. Sessions 2 and 3 demonstrated significant learning effects, particularly on the C-TMT-B, and showed good test-retest reliability. Experiment 3 examined performance in subjects instructed to feign symptoms of traumatic brain injury: 44% of subjects produced abnormal completion times on the C-TMT-A, and 18% on the C-TMT-B. Malingering subjects could be distinguished from abnormally slow controls based on (1) disproportionate increases in dwell-time on the C-TMT-A, and (2) greater deficits on the C-TMT-A than on the C-TMT-B. Experiment 4 examined the performance of 28 patients with traumatic brain injury: C-TMT-B completion times were slowed, and TBI patients showed reduced movement velocities on both tests. The C-TMT improves the reliability and sensitivity of the trail making test of processing speed and executive function. PMID:26060999

  5. Ultrasound velocity test to decay evaluation on decorative stone after different artificial ageing treatments

    NASA Astrophysics Data System (ADS)

    Fioretti, Giovanna; Andriani, Gioacchino Francesco

    2016-04-01

    Ultrasound propagation velocity depends on several physical properties, for instance density, porosity and textural discontinuities within stones. These properties are strongly influenced by state of conservation of materials and their modification can be considered decay markers; therefore, ultrasound velocity measurement represents a non-destructive technique to evaluate the decay underway on employed stone. In this study, samples of the Avorio variety, an Apulian limestones, were processed to artificial ageing treatments, in particular thermal shocks, extreme thermal exposure at high temperatures between 200 and 600°C, and cycles of immersion of rock samples into saline solution alternating with drying phases in muffle furnace. Effects of induced deterioration were examined by comparing p-wave ultrasound velocity values, visual appearance and mass loss with water absorption values and capillarity test results. This research suggests first that the ultrasound velocity test can be considered a valuable non-invasive technique to assess the state of decay of decorative and building stones. Furthermore, in order to simulate dangerous and extreme environmental conditions and study their influence on the stone decay patterns, new considerations and suggestions about ageing test and procedures were proposed.

  6. Empirical Testing of a Theoretical Extension of the Technology Acceptance Model: An Exploratory Study of Educational Wikis

    ERIC Educational Resources Information Center

    Liu, Xun

    2010-01-01

    This study extended the technology acceptance model and empirically tested the new model with wikis, a new type of educational technology. Based on social cognitive theory and the theory of planned behavior, three new variables, wiki self-efficacy, online posting anxiety, and perceived behavioral control, were added to the original technology…

  7. 75 FR 76708 - Extension of the Date by Which Youth All-Terrain Vehicles Must Be Tested and Certified

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-09

    ..., all provisions of the notice of requirements published on August 27, 2010, 75 FR 52616, remain in... FR 52616) (accessible at http://www.cpsc.gov/businfo/frnotices/fr10/atv.pdf ), the Commission...'' testing performed by a third party conformity assessment body (75 FR at 52618). The notice also asked...

  8. Crater Count Ages of Young Martian Ray Craters: a Successful Test of the Crater Chronometry System

    NASA Astrophysics Data System (ADS)

    Hartmann, William K.; Quantin, C.; Werner, S. C.; Popova, O.

    2008-09-01

    McEwen et al. (2005) developed a useful test of crater-count chronometry systems [1]. They argued that fresh-looking, Zunil-style Martian ray craters are the youngest or near-youngest craters in their size ranges. The "McEwen et al. test" is that crater-count ages from small craters (D 10-25 m), superimposed on these "Zunils," should be comparable to the expected formation intervals of these host Zunil-style primaries themselves, typically 1 to a few My. McEwen et al., however, found few or no small superposed craters in MOC frames, and concluded that crater chronometry systems are in error by factors of 700 to 2000. Since then, Malin et al. discovered that 10-25m craters form at essentially the rate we used in our isochron system [2,3,4]. Thus, 10-25m craters should be usable for dating these "Zunils." We re-evaluate the "McEwen et al. test" with HiRise images, studying three young craters they discussed, and five others. In every case we found small-crater populations, giving approximately the expected ages. We conclude that the alleged large errors are incorrect. The semi-independent crater count systems of Neukum and of Hartmann agree with the Malin cratering rate, are internally consistent, and appear to give valid age information within about a factor 2 to 4. We thank the International Space Science Institute (ISSI), Bern, for hosting our working group. [1] McEwen et al. 2005 Icarus,176, 351-381. [2] Malin, M. et al. 2006 Science 314, 1573-1557. [3] Hartmann, W.K. 2007 Icarus, 189, 274-278. [4] Kreslavsky, M.A. 2007 7th Internatl. Conf. on Mars, Abstract 3325.

  9. Study of Effect of Age and Gender Related Differences on Common Paper and Pencil Neurocognitive Tests in Adolescents

    PubMed Central

    Sharma, Vivek Kumar; A, Vinayathan; R, Sarah; SR, Balasubramaniam; S, Velkumary

    2014-01-01

    Background: Neurocognitive tests are routinely used to assess cognitive domains in the adolescents for assessing cognitive deficits and for therapeutic interventions. Now they are being used to assess their mental abilities in athletics too. Aim: To study the effect of age and gender differences on routinely used common paper and pencil neuro-cognitive tests in adolescents and present the trends of normative data of Indian adolescent population. Settings and Design: Present study was conducted as a joint collaboration between Department of Physiology and Jawahar Navodaya school, Puducherry, India. Materials and Methods: Four hundred and thirty nine adolescents in the age group of 12 to 17 y (M = 250, F= 189) were selected in the present study after meeting the inclusion and exclusion criteria. Subjects were administered commonly used paper and pencil neuropsychological tests in the following order: Two Target Letter Cancellation test, Trail Making test A and B, Ruff Figural Fluency test (RFFT). Statistical Analysis: We divided the students based on their age into six groups - from age 12–17. Neurocognitive parameters were compared between these age groups using one-way-ANOVA with Bonferroni post-hoc test. Only the p-values for one, two and three year difference were considered. The same analysis was repeated for each gender separately. We compared males and females from the entire sample using unpaired t test. We then repeated the same test to compare males and females in each age group separately. Pearsons correlation was done to find correlation between the neurocognitive test parameters using the entire sample size. Then the correlation was done again after adjusting for age. All the statistical analysis was done using Statistical package for social sciences (SPSS) version 19. Results: Year wise normative data has been presented for all the age groups from 12 y onwards to 17 y. The results showed a consistent improvement in performance on the tested neuro

  10. [The contradictive tendencies in medical treatment of the Hellenistic age--diversity versus simplification, chronic extension (physical therapy) versus rapidity, humane medicine versus worldly success].

    PubMed

    Che, Jayoung

    2008-06-01

    It is a one-sided view to find the greatness of Hippocrates just in seeking after scientific medicine (medicina scientia) and sublating superstitious treatment. The scientific medicine did not begin with him, and the succeeding generations of him were not one and the same in opinions. For example, there were the confrontations between the school of Kos and that of Knidos in the very age of Hippocrates, as well as the opposition of rationalism and empiricism. The school of Kos was alleged to succeed the tradition of Hippocrates, taking into consideration individual physical conditions and being based on the principle of various clinical methods of physical therapy assuming chronical extension. On the contrary, the school of Knidos tended to define the diseases in simple aspects, paying no much attention to the difference of physical conditions and developmental stages of illness. Futhermore, the latter grasped the diseases rather in the point of individual organs than the disorder of physical state of the body. It can be said that the anatomical knowledge was more useful for the school of Knidos. The difference between the two schools can also be found in what purpose the medicine sought after. While Hippocrates attached much importance to physical therapy and made the people including the poor as object of medical treatment, there were doctors in no small number, we can suppose, in pursuit of money, power, worldly glory. As time passed, however, the two schools gradually got similar to each other, the difference of them reduced as well as the tradition of Hippocrates faded. The opposition between rationalism and empiricism in the Hellenistic Age shared, in some aspect, the difference of Kos and Knidos. According to Celsus, the conflict between rationalism and empiricism did not refer to pharmacy or anatomy, but just to diet. The rationalism materialized various methods of therapy considering environmental elements as well as individual physical conditions, but the

  11. Lap Shear and Impact Testing of Ochre and Beeswax in Experimental Middle Stone Age Compound Adhesives.

    PubMed

    Kozowyk, P R B; Langejans, G H J; Poulis, J A

    2016-01-01

    The production of compound adhesives using disparate ingredients is seen as some of the best evidence of advanced cognition outside of the use of symbolism. Previous field and laboratory testing of adhesives has shown the complexities involved in creating an effective Middle Stone Age glue using Acacia gum. However, it is currently unclear how efficient different adhesive recipes are, how much specific ingredients influence their performance, and how difficult it may have been for those ingredients to be combined to maximum effect. We conducted a series of laboratory-based lap shear and impact tests, following modern adhesion testing standards, to determine the efficacy of compound adhesives, with particular regard to the ingredient ratios. We tested rosin (colophony) and gum adhesives, containing additives of beeswax and ochre in varying ratios. During both lap shear and impact tests compound rosin adhesives performed better than single component rosin adhesives, and pure acacia gum was the strongest. The large difference in performance between each base adhesive and the significant changes in performance that occur due to relatively small changes in ingredient ratios lend further support to the notion that high levels of skill and knowledge were required to consistently produce the most effective adhesives. PMID:26983080

  12. Lap Shear and Impact Testing of Ochre and Beeswax in Experimental Middle Stone Age Compound Adhesives

    PubMed Central

    2016-01-01

    The production of compound adhesives using disparate ingredients is seen as some of the best evidence of advanced cognition outside of the use of symbolism. Previous field and laboratory testing of adhesives has shown the complexities involved in creating an effective Middle Stone Age glue using Acacia gum. However, it is currently unclear how efficient different adhesive recipes are, how much specific ingredients influence their performance, and how difficult it may have been for those ingredients to be combined to maximum effect. We conducted a series of laboratory-based lap shear and impact tests, following modern adhesion testing standards, to determine the efficacy of compound adhesives, with particular regard to the ingredient ratios. We tested rosin (colophony) and gum adhesives, containing additives of beeswax and ochre in varying ratios. During both lap shear and impact tests compound rosin adhesives performed better than single component rosin adhesives, and pure acacia gum was the strongest. The large difference in performance between each base adhesive and the significant changes in performance that occur due to relatively small changes in ingredient ratios lend further support to the notion that high levels of skill and knowledge were required to consistently produce the most effective adhesives. PMID:26983080

  13. SEE and TID extension testing of the Xilinx XQR18V04 4Mbit radiation hardened configuration PROM

    NASA Technical Reports Server (NTRS)

    Yui, C.; Swift, G.; Fabula, J.; Carmichael, C.

    2002-01-01

    The XQR18V04 was evaluated for single event upset rates using proton and heavy ions. The PROM was demonstrated to be immune to latch-up, as well as to static upset in the flash memory cells, to an LET > 125 MeV/mg/cmz (effective). The PROM was also tested in a dynamic mode, which revealed three distinct error modes: Read Bit Errors, Address Errors, and a Single Event Functional Interrupt (SEW which affected the data output drivers. Saturation cross-sections, and onset thresholds, for these errorinodes were measured at the heavy ion facility at Texas A&M University, and the proton facility at UC Davis. Additional testing was performed at UC Davis and the Cobalt 60 source at McClellan Air Force Base to examine the effect to TID life as a function of power biasing. The PROM demonstrated a 100% improvement in total TID life with an 84% percent decrease in device usage.

  14. Low amplitude impact testing and analysis of pristine and aged solid high explosives

    SciTech Connect

    Chidester, S K; Garza, R; Tarver, C M

    1998-08-17

    The critical impact velocities of 60.1 mm diameter blunt steel projectiles required for ignition of exothermic chemical reaction were determined for heavily confined charges of new and aged (15-30 years) solid HMX-based high explosives. The explosives in order of decreasing impact sensitivity were: PBX 9404; LX-lo; LX-14; PBX 9501; and LX-04. Embedded pressure gauges measured the interior pressure histories. Stockpile aged LX-04 and PBX 9501 from dismantled units were tested and compared to freshly pressed charges. The understanding of explosive aging on impact ignition and other hazards must improve as systems are being deployed longer than their initial estimated lifetimes. The charges that did not react on the first impact were subjected to multiple impacts. While the violence of reaction increased with impact velocity, it remained much lower than that produced by an intentional detonation. Ignition and Growth reactive flow models were developed to predict HMX-based explosive impact sensitivity in other geometries and scenarios.

  15. Right-Left Differences in Knee Extension Stiffness for the Normal Rat Knee: In Vitro Measurements Using a New Testing Apparatus.

    PubMed

    Markolf, Keith L; Evseenko, Denis; Petrigliano, Frank

    2016-04-01

    Knee stiffness following joint injury or immobilization is a common clinical problem, and the rat has been used as a model for studies related to joint stiffness and limitation of motion. Knee stiffness measurements have been reported for the anesthetized rat, but it is difficult to separate the contributions of muscular and ligamentous restraints to the recorded values. in vitro testing of isolated rat knees devoid of musculature allows measurement of joint structural properties alone. In order to measure the effects of therapeutic or surgical interventions designed to alter joint stiffness, the opposite extremity is often used as a control. However, right-left stiffness differences for the normal rat knee have not been reported in the literature. If stiffness changes observed for a treatment group are within the normal right-left variation, validity of the results could be questioned. The objectives of this study were to utilize a new testing apparatus to measure right-left stiffness differences during knee extension in a population of normal rat knees and to document repeatability of the stiffness measurements on successive testing days. Moment versus rotation curves were recorded for 15 right-left pairs of normal rat knees on three consecutive days, with overnight specimen storage in a refrigerator. Each knee was subjected to ten loading-unloading cycles, with the last loading curve used for analysis. Angular rotation (AR), defined here as the change in flexion-extension angle from a specified applied joint moment, is commonly used as a measure of overall joint stiffness. For these tests, ARs were measured from the recorded test curves with a maximum applied extension moment of 100 g cm. Mean rotations for testing days 2 and 3 were 0.81-1.25 deg lower (p < 0.001) than for day 1, but were not significantly different from each other. For each testing day, mean rotations for right knees were 1.12-1.30 deg greater (p < 0.001) than left knees. These right

  16. Tests of an extension of the dual pathway model of bulimic symptoms to the state-based level.

    PubMed

    Holmes, Millicent; Fuller-Tyszkiewicz, Matthew; Skouteris, Helen; Broadbent, Jaclyn

    2014-04-01

    The dual pathway model proposes that trait body dissatisfaction leads to bulimic symptoms via two distinct pathways: dieting and trait negative affect. As many of these modelled variables have state-based equivalents, the present study evaluated the generalisability of this model to predict associations between state body dissatisfaction and instances of disordered eating. 124 women aged 18 to 40 years completed an online survey (accessed via a mobile phone device with web access) over a 7-day period. The mobile phone device prompted participants at random intervals seven times daily to self-report their state body dissatisfaction, current mood experiences, dieting attempts, and disordered eating practices. Multi-level mediation modelling revealed that both negative mood states and dieting significantly mediated the state body dissatisfaction-disordered eating relationships, although the strength of these associations depended on the aspect of disordered eating measured and individual differences in trait body dissatisfaction, internalization of appearance standards, tendency towards dieting, and BMI. Collectively, these results not only support adapting the dual pathway model to the state-level, but also suggest that several of the model implied pathways may be more relevant for individuals with more pathological eating- and body-related concerns and behaviours. PMID:24854819

  17. ASTM international symposium on small specimen test techniques and their applications to pressure vessel annealing and plant life extension

    SciTech Connect

    Garner, F.A.; Hamilton, M.L.; Heinisch, H.L.; Kumar, A.S.

    1992-01-01

    Miniature sheet-type tensile specimens are currently being used in a variety of radiation damage studies conducted in a number of different reactors. Although these specimens are very small, they have proven successful in addressing issues encountered in both thermal reactors and anticipated fusion reactors. This paper reviews the results of a number of recent studies that illustrate the range of applicability of these small specimens. When combined with other types of specimens and other types of measurements made prior to tensile testing, miniature tensile specimens have been found to serve as very useful tools for application to both fundamental studies and alloy screening studies.

  18. Testing exhumation models using PTt paths: an Alpine perspective based on deformation ages

    NASA Astrophysics Data System (ADS)

    Reddy, S.; Butler, R.; Wheeler, J.; Cliff, B.; Freeman, S.; Biggs, A.

    2005-12-01

    Geochronological data are now commonly used to establish the timing and rates of exhumation of high pressure metamorphic rocks, critical for testing geodynamic models of orogenic belts. Such approaches must be used with care. Ages of peak pressure metamorphic assemblages allied to younger cooling ages give a general insight into the rates of exhumation when tied to PT paths. However, the results of this workflow are difficult to relate to the kinematic history and therefore maybe of limited use in the critical testing of exhumation models. An alternative strategy is to date directly synkinematic mineral phases in characterised deformation zones. Examples are drawn from the deformed and variably subducted "European" continental crust now exposed in the Western Alps to illustrate this, chiefly using Rb-Sr mica dating, applied to greenschist facies shear zones. Some structures are synchronously active for c. 100km along strike (e.g. the regional "retrocharriage" shear system of the Eastern Brianconnais: 34 Ma). However, UHP terrains of the basement massifs attained peak pressures and were exhumed diachronously (38 Ma - 32 Ma). These results indicate that tectono-metamorphic histories based on single orogenic transects may give misleading pictures of geodynamic evolution. In an Alpine context it appears that exhumation of UHP and shallower parts of the evolving continental subduction channel occurred as variably detached flakes rather than relate to the dynamics of larger scale plate processes.

  19. Facial averageness and genetic quality: Testing heritability, genetic correlation with attractiveness, and the paternal age effect

    PubMed Central

    Lee, Anthony J.; Mitchem, Dorian G.; Wright, Margaret J.; Martin, Nicholas G.; Keller, Matthew C.; Zietsch, Brendan P.

    2015-01-01

    Popular theory suggests that facial averageness is preferred in a partner for genetic benefits to offspring. However, whether facial averageness is associated with genetic quality is yet to be established. Here, we computed an objective measure of facial averageness for a large sample (N = 1,823) of identical and nonidentical twins and their siblings to test two predictions from the theory that facial averageness reflects genetic quality. First, we use biometrical modelling to estimate the heritability of facial averageness, which is necessary if it reflects genetic quality. We also test for a genetic association between facial averageness and facial attractiveness. Second, we assess whether paternal age at conception (a proxy of mutation load) is associated with facial averageness and facial attractiveness. Our findings are mixed with respect to our hypotheses. While we found that facial averageness does have a genetic component, and a significant phenotypic correlation exists between facial averageness and attractiveness, we did not find a genetic correlation between facial averageness and attractiveness (therefore, we cannot say that the genes that affect facial averageness also affect facial attractiveness) and paternal age at conception was not negatively associated with facial averageness. These findings support some of the previously untested assumptions of the ‘genetic benefits’ account of facial averageness, but cast doubt on others. PMID:26858521

  20. A step forward in the quality control testing of inactivated rabies vaccines - extensive evaluation of European vaccines by using alternative methods to the in vivo potency tests.

    PubMed

    Servat, Alexandre; Kempff, Sébastien; Brogat, Valère; Litaize, Estelle; Schereffer, Jean-Luc; Cliquet, Florence

    2015-03-01

    The mouse challenge test still remains the reference method for the potency determination of human and animal inactivated rabies vaccines, and it is still widely used throughout the world. This test suffers from many disadvantages - it is expensive and time consuming, uses a large number of mice, causes significant animal distress, and suffers from high variability. Recently, the European Pharmacopoeia has recognised the use of a serological potency assay (SPA) as an alternative method to the challenge test. This new test is based on the determination of rabies neutralising antibody titres in vaccinated mice, by using the modified Rapid Fluorescent Focus Inhibition Test (mRFFIT). With the objective of adopting this new method for the batch release of inactivated rabies vaccines, we evaluated its performance on a large collection of rabies vaccines currently assessed in our laboratory. The Fluorescent Antibody Virus Neutralisation test (FAVNt) was used in parallel with the mRFFIT, and the results were compared to the mouse challenge test. Our results demonstrate that the SPA is capable of estimating the potency of vaccines formulated with a potency margin well above the minimum of 1IU/dose. For low potency vaccines, this new method demonstrated some limitations, due to the recurrent invalidation of the assay. We have also demonstrated the superior sensitivity of the FAVNt when compared to the mRFFIT, and the importance of minimising the risk of detecting non-responders in vaccinated mice. PMID:25802995

  1. Polymer-Oxygen Compatibility Testing: Effect of Oxygen Aging on Ignition and Combustion Properties

    NASA Technical Reports Server (NTRS)

    Waller, Jess M.; Haas, Jon P.; Wilson, D. Bruce; Fries, Joseph (Technical Monitor)

    2000-01-01

    The oxygen compatibility of six polymers used in oxygen service was evaluated after exposure for 48 hours to oxygen pressures ranging from 350 to 6200 kPa (50 to 900 psia), and temperatures ranging from 50 to 250 C (122 to 302 F). Three elastomers were tested: CR rubber (C873-70), FKM fluorocarbon rubber (Viton A), and MPQ silicone rubber (MIL-ZZ-765, Class 2); and three thermoplastics were tested: polyhexamethylene adipamide (Zytel 42), polytetrafluoroethylene (Teflon TFE), and polychlorotrifluoroethylene (Neoflon CTFE M400H). Post-aging changes in mass, dimensions, tensile strength, elongation at break, and durometer hardness were determined. Also, the compression set was determined for the three elastomers. Results show that the properties under investigation were more sensitive to oxygen pressure at low to moderate temperatures, and more sensitive to temperature at low to moderate oxygen pressures. Inspection of the results also suggested that both chain scissioning and cross-linking processes were operative, consistent with heterogeneous oxidation. Attempts are underway to verify conclusively the occurrence of heterogeneous oxidation using a simple modulus profiling technique. Finally, the effect of aging at 620 kpa (90 psia) and 121 C (250 F) on ignition and combustion resistance was determined. As expected, aged polymers were less ignitable and combustible (had higher AlTs and lower heats of combustion). Special attention was given to Neoflon CTFE. More specifically, the effect of process history (compression versus extrusion molding) and percent crystallinity (quick- versus slow-quenched) on the AIT, heat of combustion, and impact sensitivity of Neoflon CTFE was investigated. Results show the AIT, heat of combustion, and impact sensitivity to be essentially independent of Neoflon CTFE process history and structure.

  2. The Graphic Pattern Generation Test in Healthy Aging and Alzheimer's Disease: Psychometric Properties and Normative Data

    PubMed Central

    Sunderaraman, Preeti; Sokolov, Elisaveta; Cines, Sarah; Sullo, Elizabeth; Orly, Aidan; Lerer, Bianca; Karlawish, Jason; Huey, Edward; Cosentino, Stephanie

    2015-01-01

    Design fluency tests, commonly used in both clinical and research contexts to evaluate nonverbal concept generation, have the potential to offer useful information in the differentiation of healthy versus pathological aging. While normative data for older adults are available for multiple timed versions of this test, similar data have been unavailable for a previously published untimed task, the Graphic Pattern Generation Task (GPG). Time constraints common to almost all of the available design fluency tests may cloud interpretation of higher level executive abilities, for example in individuals with slow processing speed. The current study examined the psychometric properties of the GPG and presents normative data in a sample of 167 healthy older adults (OAs) and 110 individuals diagnosed with Alzheimer's disease (AD). Results suggest that a brief version of the GPG can be administered reliably, and that this short form has high test-retest and inter-rater reliability. Number of perseverations was higher in individuals with AD as compared to OAs. A cut-off score of 4 or more perseverations showed a moderate degree of sensitivity (76%) and specificity (37%) in distinguishing individuals with AD and OAs. Finally, perseverations were associated with nonmemory indices, underscoring the nonverbal nature of this error in OAs and individuals with AD. PMID:25679880

  3. Testing Age-Paced Parenting Newsletters up to Age 3: Greater Impact on First-Time Parents

    ERIC Educational Resources Information Center

    Ostergren, Carol S.; Riley, David A.

    2012-01-01

    An age-paced newsletter for parents of toddlers was evaluated. Mothers reported the newsletters were as useful as information from doctors or nurses and more useful than other sources of information. We hypothesized and found that first-time mothers reported the newsletters more useful than experienced mothers--reading more of the newsletters and…

  4. COMBINING LIDAR ESTIMATES OF BIOMASS AND LANDSAT ESTIMATES OF STAND AGE FOR SPATIALLY EXTENSIVE VALIDATION OF MODELED FOREST PRODUCTIVITY. (R828309)

    EPA Science Inventory

    Extensive estimates of forest productivity are required to understand the
    relationships between shifting land use, changing climate and carbon storage
    and fluxes. Aboveground net primary production of wood (NPPAw) is a major component
    of total NPP and...

  5. The New Digital [St]age: Barriers to the Adoption and Adaptation of New Technologies to Deliver Extension Programming and How to Address Them

    ERIC Educational Resources Information Center

    Seger, Jamie

    2011-01-01

    With the rise of social media and the need for statewide program cohesiveness, The Ohio State University Extension has the opportunity to position itself as a catalyst for technology adoption and adaptation nationwide. Unfortunately, many barriers exist to the successful use and implementation of technology, including an organizational structure…

  6. How did the Elimination of the Earnings Test above the Normal Retirement Age affect Retirement Expectations?1

    PubMed Central

    Michaud, Pierre-Carl

    2010-01-01

    We look at the effect of the 2000 repeal of the earnings test above the normal retirement age on retirement expectations of workers in the Health and Retirement Study, aged 51 to 61 in 1992. For men, we find that those whose marginal wage rate increased when the earnings test was repealed, had the largest increase in the probability to work full-time past normal retirement age. We do not find significant evidence of effects of the repeal of the earnings test on the probability to work past age 62 or the expected claiming age. On the other hand, for those reaching the normal retirement age, deviations between the age at which Social Security benefits are actually claimed and the previously reported expected age are more negative in 2000 than in 1998. Since our calculations show that the tax introduced by the earnings test was small when accounting for actuarial benefit adjustments and differential mortality, our results suggest that although male workers form expectations in a way consistent with forward-looking behavior, they misperceive the complicated rules of the earnings test. Results for females suggest similar patterns but estimates are imprecise. PMID:21037938

  7. Linking job demands and resources to employee engagement and burnout: a theoretical extension and meta-analytic test.

    PubMed

    Crawford, Eean R; Lepine, Jeffery A; Rich, Bruce Louis

    2010-09-01

    We refine and extend the job demands-resources model with theory regarding appraisal of stressors to account for inconsistencies in relationships between demands and engagement, and we test the revised theory using meta-analytic structural modeling. Results indicate support for the refined and updated theory. First, demands and burnout were positively associated, whereas resources and burnout were negatively associated. Second, whereas relationships among resources and engagement were consistently positive, relationships among demands and engagement were highly dependent on the nature of the demand. Demands that employees tend to appraise as hindrances were negatively associated with engagement, and demands that employees tend to appraise as challenges were positively associated with engagement. Implications for future research are discussed. PMID:20836586

  8. AGRICULTURAL EXTENSION.

    ERIC Educational Resources Information Center

    FARQUHAR, R.N.

    AUSTRALIAN AGRICULTURAL EXTENSION HAS LONG EMPHASIZED TECHNICAL ADVISORY SERVICE AT THE EXPENSE OF THE SOCIOECONOMIC ASPECTS OF FARM PRODUCTION AND FARM LIFE. ONLY IN TASMANIA HAS FARM MANAGEMENT BEEN STRESSED. DEMANDS FOR THE WHOLE-FARM APPROACH HAVE PRODUCED A TREND TOWARD GENERALISM FOR DISTRICT OFFICERS IN MOST STATES. THE FEDERAL GOVERNMENT,…

  9. Extension of in-situ stress test analysis to fractured media with reference to Yucca Mountain data

    SciTech Connect

    Davies, J.B.

    1993-05-01

    Yucca Mountain is underlain by highly fractured rock containing a deep water table. Stress tests have been performed in boreholes in-situ and under high head pressures. For a pre-fractured rock system, data analysis must incorporate the effects of opening and closing of fractures. As the head pressure increases form ambient, the aperture of the existing dilated fractures increase. The fracture surface area remains constant until the excess head increases to above a critical pressure, when induced fractures can open and existing fractures may propagate. These will furnish a larger rock surface area thereby allowing a more rapid percolation of the water into the rock matrix. We have extended previous models by specifying a functional dependence of both existing fracture aperture and induced fracture surface area and volume on the excess water pressure. Relationships are obtained through the mass conservation laws and these predictions are used as discriminative graphs, with the most useful being pressure versus rate of pressure change. Such type-curves are applied to; Yucca Mountain data with interpretation in terms of the applicable fracture systems and the critical pressure. Estimates of the critical pressure are obtained and usually lie in the range of 10 to 30 bars which is appreciably lower than that expected from the lithostatic pressure effects. This implies that large dilational stresses exist at Yucca Mountain.

  10. Moving beyond the binary with disordered eating research: a test and extension of objectification theory with bisexual women.

    PubMed

    Brewster, Melanie E; Velez, Brandon L; Esposito, Jessica; Wong, Stephanie; Geiger, Elizabeth; Keum, Brian TaeHyuk; Keum, Taehyuk Brian

    2014-01-01

    In predicting disordered eating, the core model of objectification theory (Fredrickson & Roberts, 1997) has been replicated and extended in research across most sexual minority groups (e.g., Haines et al., 2008; Wiseman & Moradi, 2010), but not bisexual women. The present study tested the tenets of objectification theory with a sample of 316 bisexual women and further extended this theory by examining the roles of 2 minority stressors-antibisexual discrimination and internalized biphobia-that are contextually salient for bisexual women. A latent variable structural equation model was conducted, and the model yielded a good fit to the data. Antibisexual discrimination and internalized biphobia (but not sexual objectification experiences) yielded significant unique links with internalization of sociocultural standards of attractiveness (internalization of CSA). Next, internalization of CSA yielded a significant unique link with body surveillance. In addition, antibisexual discrimination, internalization of CSA, and body surveillance yielded significant unique links with body shame. Finally, sexual objectification experiences, internalization of CSA, and body shame yielded significant unique links with eating disorder symptomatology. Beyond the direct relations, antibisexual discrimination yielded significant positive indirect links with body surveillance, body shame, and eating disorder symptoms. Internalization of CSA yielded significant positive indirect links with body shame and eating disorder symptoms. Lastly, body surveillance yielded a significant positive indirect link with eating disorder symptoms. Implications for research and practice with bisexual women are discussed. (PsycINFO Database Record (c) 2014 APA, all rights reserved). PMID:24188653

  11. Swimming Training Assessment: The Critical Velocity and the 400-m Test for Age-Group Swimmers.

    PubMed

    Zacca, Rodrigo; Fernandes, Ricardo Jorge P; Pyne, David B; Castro, Flávio Antônio de S

    2016-05-01

    Zacca, R, Fernandes, RJP, Pyne, DB, and Castro, FAdS. Swimming training assessment: the critical velocity and the 400-m test for age-group swimmers. J Strength Cond Res 30(5): 1365-1372, 2016-To verify the metabolic responses of oxygen consumption (V[Combining Dot Above]O2), heart rate (HR), blood lactate concentrations [La], and rate of perceived exertion (RPE) when swimming at an intensity corresponding to the critical velocity (CV) assessed by a 4-parameter model (CV4par), and to check the reliability when using only a single 400-m maximal front crawl bout (T400) for CV4par assessment in age-group swimmers. Ten age-group swimmers (14-16 years old) performed 50-, 100-, 200-, 400- (T400), 800-, and 1,500-m maximal front crawl bouts to calculate CV4par. V[Combining Dot Above]O2, HR, [La], and RPE were measured immediately after bouts. Swimmers then performed 3 × 10-minute front crawl (45 seconds rest) at CV4par. V[Combining Dot Above]O2, HR, [La], and RPE were measured after 10 minutes of rest (Rest), warm-up (Pre), each 10-minute repetition, and at the end of the test (Post). CV4par was 1.33 ± 0.08 m·s. V[Combining Dot Above]O2, HR, [La], and RPE were similar between first 10-minute and Post time points in the 3 × 10-minute protocol. CV4par was equivalent to 92 ± 2% of the mean swimming speed of T400 (v400) for these swimmers. CV4par calculated through a single T400 (92%v400) showed excellent agreement (r = 0.30; 95% CI: -0.04 to 0.05 m·s, p = 0.39), low coefficient of variation (2%), and root mean square error of 0.02 ± 0.01 m·s when plotted against CV4par assessed through a 4-parameter model. These results generated the equation CV4par = 0.92 × v400. A single T400 can be used reliably to estimate the CV4par typically derived with 6 efforts in age-group swimmers. PMID:26473520

  12. Wind-Tunnel Tests of Several Model Tractor-Propeller and Pusher-Propeller Wing Extension-Shaft Arrangements, Special Report

    NASA Technical Reports Server (NTRS)

    Harmon, Hubert N.

    1941-01-01

    Tests were made in the 20-foot propeller-research tunnel to investigate the possibility of obtaining increased net efficiencies of propeller-nacelle units by enclosing the engines in the wings and by using extension shafts. A wing of 5-foot chord was fitted with a propeller drive assembly providing for several axial locations of tractor propellers and pusher propellers. A three-blade 4-foot propeller and a three-blade 3 1/2-foot propeller of special design were tested in this wing with spinners and fairings ranging in diameter from 6 to 16 inches. A 16-inch NACA cowling was tested for comparative purposes. Two types of cuffs were also employed. It was found that the net efficiency of a conventional round-shank propeller mounted on an extension shaft in front of or behind a wing increased with an increase in the diameter of the spinner and the shaft housing within the scope of the tests. The largest spinner used had a diameter that might favorably compare with that of a radial engine cowling. The efficiencies for the pusher position appeared to be more critically affected by spinner size than those for the tractor position. The spinners with large diameters for the pusher position resulted in a higher efficiency than those for the corresponding tractor arrangements; the reverse was true for the small spinners. The use of propeller cuffs in combination with a spinner of small diameter generally resulted in net efficiencies that were comparable with those found for the large-spinner combinations.

  13. Evaluation of stone durability using a combination of ultrasound, mechanical and accelerated aging tests

    NASA Astrophysics Data System (ADS)

    Molina, E.; Cultrone, G.; Sebastián, E.; Alonso, F. J.

    2013-06-01

    The durability of a rock when exposed to decay agents is an important criterion when assessing its quality as a building material. Our study focuses on six varieties of natural stone (two limestones, one dolostone, one travertine and two sandstones) that are widely used in both new and historical buildings. In order to assess their quality, we measured and characterized their dynamic elastic properties using ultrasounds, we measured their compressive strength using the uniaxial compression test and we evaluated their durability by means of accelerated aging tests (freeze-thaw and salt crystallization). In order to get a full picture of the decay suffered by the different stones, we determined the composition and amount of the clay fraction of the six stones. We also observed small fragments subjected to the salt crystallization test under an environmental scanning electron microscope to study any textural change and measured the changes of colour on the surface with a spectrophotometer. Finally, we analysed the pore system of the stones before and after their deterioration using mercury injection porosimetry. We then compared the results for the different stones and found that dolostone obtained the best results, while the two limestones proved to be the least durable and had the lowest compressive strength.

  14. Montenegro skin test and age of skin lesion as predictors of treatment failure in cutaneous leishmaniasis.

    PubMed

    Antonio, Liliane de Fátima; Fagundes, Aline; Oliveira, Raquel Vasconcellos Carvalhaes; Pinto, Priscila Garcia; Bedoya-Pacheco, Sandro Javier; Vasconcellos, Erica de Camargo Ferreira e; Valete-Rosalino, Maria Cláudia; Lyra, Marcelo Rosandiski; Passos, Sônia Regina Lambert; Pimentel, Maria Inês Fernandes; Schubach, Armando de Oliveira

    2014-01-01

    A case-control study was conducted to examine the association among the Montenegro skin test (MST), age of skin lesion and therapeutic response in patients with cutaneous leishmaniasis (CL) treated at Evandro Chagas National Institute of Infectious Diseases (INI), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, Brazil. For each treatment failure (case), two controls showing skin lesion healing following treatment, paired by sex and age, were randomly selected. All patients were treated with 5 mg Sb(5+)/kg/day of intramuscular meglumine antimoniate (Sb(5+)) for 30 successive days. Patients with CL were approximately five times more likely to fail when lesions were less than two months old at the first appointment. Patients with treatment failure showed less intense MST reactions than patients progressing to clinical cure. For each 10 mm of increase in MST response, there was a 26% reduction in the chance of treatment failure. An early treatment - defined as a treatment applied for skin lesions, which starts when they are less than two months old at the first appointment -, as well as a poor cellular immune response, reflected by lower reactivity in MST, were associated with treatment failure in cutaneous leishmaniasis. PMID:25229216

  15. MONTENEGRO SKIN TEST AND AGE OF SKIN LESION AS PREDICTORS OF TREATMENT FAILURE IN CUTANEOUS LEISHMANIASIS

    PubMed Central

    Antonio, Liliane de Fátima; Fagundes, Aline; Oliveira, Raquel Vasconcellos Carvalhaes; Pinto, Priscila Garcia; Bedoya-Pacheco, Sandro Javier; Vasconcellos, Érica de Camargo Ferreira e; Valete-Rosalino, Maria Cláudia; Lyra, Marcelo Rosandiski; Passos, Sônia Regina Lambert; Pimentel, Maria Inês Fernandes; Schubach, Armando de Oliveira

    2014-01-01

    A case-control study was conducted to examine the association among the Montenegro skin test (MST), age of skin lesion and therapeutic response in patients with cutaneous leishmaniasis (CL) treated at Evandro Chagas National Institute of Infectious Diseases (INI), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, Brazil. For each treatment failure (case), two controls showing skin lesion healing following treatment, paired by sex and age, were randomly selected. All patients were treated with 5 mg Sb5+/kg/day of intramuscular meglumine antimoniate (Sb5+) for 30 successive days. Patients with CL were approximately five times more likely to fail when lesions were less than two months old at the first appointment. Patients with treatment failure showed less intense MST reactions than patients progressing to clinical cure. For each 10 mm of increase in MST response, there was a 26% reduction in the chance of treatment failure. An early treatment - defined as a treatment applied for skin lesions, which starts when they are less than two months old at the first appointment -, as well as a poor cellular immune response, reflected by lower reactivity in MST, were associated with treatment failure in cutaneous leishmaniasis. PMID:25229216

  16. Development of a Detonation Profile Test for Studying Aging Effects in LX-17

    SciTech Connect

    Tran, T; Lewis, P; Tarver, C; Maienschein, J; Druce, R; Lee, R; Roeske, F

    2002-03-25

    A new small-scale Detonation Profile Test (DPT) is being developed to investigate aging effects on the detonation behavior of insensitive high explosives. The experiment involves initiating a small LX-17 cylindrical charge (12.7-19.1 mm diameter x 25.4-33 mm long) and measuring the velocity and curvature of the emerging detonation wave using a streak camera. Results for 12.7 mm diameter unconfined LX-17 charges show detonation velocity in the range between 6.79 and 7.06 km/s for parts up to 33 mm long. Since LX-17 can not sustain detonation at less than 7.3 km/s, these waves were definitely failing. Experiments with confined 12.7 mm diameter and unconfined 19.1 mm diameter samples showed wave velocities in the range of 7.4-7.6 km/s, values approaching steady state conditions at infinite diameter. Experiments with unconfined 19.1 mm diameter specimens are expected to provide reproducible and useful range of detonation parameters suitable for studying aging effects.

  17. Single and multiple impact ignition of new and aged high explosives in the Steven Impact Test

    SciTech Connect

    Chidester, S K; DePiero, A H; Garza, R G; Tarver, C M

    1999-06-01

    Threshold impact velocities for ignition of exothermic reaction were determined for several new and aged HMX-based solid high explosives using three types of projectiles in the Steven Test. Multiple impact threshold velocities were found to be approximately 10% lower in damaged charges that did not react in one or more prior impacts. Projectiles with protrusions that concentrate the friction work in a small volume of explosive reduced the threshold velocities by approximately 30%. Flat projectiles required nearly twice as high velocities for ignition as rounded projectiles. Blast overpressure gauges were used for both pristine and damaged charges to quantitatively measure reaction violence. Reactive flow calculations of single and multiple impacts with various projectiles suggest that the ignition rates double in damaged charges.

  18. Throttling Characteristics of the RL10 Derivative Common Extensible Cryogenic Engine -- Demo 1.6 and 1.7 Test Results

    NASA Technical Reports Server (NTRS)

    Devine, Matthew K.; Hulka, James; Adamski, Walt; Brown, Corey

    2010-01-01

    The Common Extensible Cryogenic Engine (CECE) is a deep throttling cryogenic Lunar Module Descent Engine (LMDE) technology development demonstrator based on the Pratt & Whitney Rocketdyne (PWR) RL10 engine. Previous testing on this engine occurred during 2006 as Demo 1.0, then Demo 1.5 in 2007, Demo 1.6 in 2008 and finally Demo 1.7 in 2010. A review of Demo 1.0, 1.5, and preliminary results of 1.6 were reported in previous JANNAF papers. Demo 1.6 was tested at the PWR E-6 test facility in November 2008. The primary goal of this series was to mitigate low frequency combustion instability observed at low power levels. To mitigate the chug, the Demo 1.6 injector was modified from the previous configurations to include an approximately 0.050 inch thick teflon-type spray-on insulation to reduce heat transfer to the LOX manifold, which was believed to be a significant contributor to the low power instability. In addition, gaseous helium injection into the LOX manifold was used as a means to stabilize the system. Also explored in this test series was mitigation for a low power 1 Hz fuel system oscillation caused by sub-critical hydrogen boiling in the chamber cooling jacket. Reduced area gas venturis were utilized to avoid the 1 Hz fuel-size oscillation by keeping the cooling jacket supercritical down to lower engine power levels. Demo 1.7 began testing in March 2010. Its primary objectives were to demonstrate closed loop control capability on mixture ratio and chamber pressure, start to lower power levels and increased throttling ramp rates. Secondary test objectives that are discussed include multiple engine starts, higher mixture ratio excursions and additional time at low power level. While the complete test series and data reduction is not yet complete for Demo 1.7, an overview and up-to-date status is provided.

  19. Signature extension studies

    NASA Technical Reports Server (NTRS)

    Vincent, R. K.; Thomas, G. S.; Nalepka, R. F.

    1974-01-01

    The importance of specific spectral regions to signature extension is explored. In the recent past, the signature extension task was focused on the development of new techniques. Tested techniques are now used to investigate this spectral aspect of the large area survey. Sets of channels were sought which, for a given technique, were the least affected by several sources of variation over four data sets and yet provided good object class separation on each individual data set. Using sets of channels determined as part of this study, signature extension was accomplished between data sets collected over a six-day period and over a range of about 400 kilometers.

  20. Abnormal ventilation scans in middle-aged smokers. Comparison with tests of overall lung function

    SciTech Connect

    Barter, S.J.; Cunningham, D.A.; Lavender, J.P.; Gibellino, F.; Connellan, S.J.; Pride, N.B.

    1985-07-01

    The uniformity of regional ventilation during tidal breathing has been assessed using continuous inhalation of krypton-81m in 43 male, lifelong nonsmokers and 46 male, current cigarette smokers (mean daily consumption 24.1 cigarettes/day) between 44 and 61 yr of age and with mild or no respiratory symptoms. All subjects had normal chest radiographs. The results of the ventilation scans were compared with tests of overall lung function (spirometry, maximal expiratory flow-volume curves, and single-breath N2 test). Diffuse abnormalities of the ventilation scan were found in 19 (41%) of the 46 smokers but in none of the nonsmokers. Focal abnormalities were found in 7 smokers and 3 nonsmokers. Smokers showed the expected abnormalities in overall lung function (reduced FEV1 and VC, increased single-breath N2 slope, and closing volume), but in individual smokers there was only a weak relation between the severity of abnormality of overall lung function and an abnormal ventilation scan. Abnormal scans could be found when overall lung function was normal and were not invariably found when significant abnormalities in FEV1/VC or N2 slope were present. There was no relation between the presence of chronic expectoration and an abnormal scan. The prognostic significance of an abnormal ventilation scan in such smokers remains to be established.

  1. Degradation mechanism of LiCoO2/mesocarbon microbeads battery based on accelerated aging tests

    NASA Astrophysics Data System (ADS)

    Guan, Ting; Zuo, Pengjian; Sun, Shun; Du, Chunyu; Zhang, Lingling; Cui, Yingzhi; Yang, Lijie; Gao, Yunzhi; Yin, Geping; Wang, Fuping

    2014-12-01

    A series of LiCoO2/mesocarbon microbeads (MCMB) commercial cells cycled at different rates (0.6C, 1.2C, 1.5C, 1.8C, 2.4C and 3.0C) are disassembled and the capacity fade mechanism is proposed by analyzing the structure, morphology and electrochemical performance evolution at the capacity retention of 95%, 90%, 85%, 80%. The capacity deterioration of the commercial cell is mainly caused by the decay of the reversible capacity of LiCoO2 cathode, the irreversible loss of active lithium and the lithium remaining in anode. The proportions of effects by the above three factors are calculated accurately. The consumption of the active lithium leads to a cell imbalance between the anode and the cathode. The electrochemical test results indicate that the capacity fade of the active materials at the low rate is more obvious than that at the high rate. The influence of the active lithium is gradually increscent with the increasing rate. The rate of 1.5C is the optimal value to accelerate the aging of the full cell by comparing the testing results at different capacity retentions in the specific condition of low charge/discharge rate and shallow depth of discharge.

  2. Effects of Age and Cognition on a Cross-Cultural Paediatric Adaptation of the Sniffin' Sticks Identification Test

    PubMed Central

    Guerreiro, Marilisa Mantovani; Lees, Andrew John; Warner, Thomas T.

    2015-01-01

    Objectives To study the effects of age and cognition on the performance of children aged 3 to 18 years on a culturally adapted version of the 16 item smell identification test from Sniffin' Sticks (SS16). Methods A series of pilots were conducted on 29 children aged 3 to 18 years old and 23 adults to produce an adapted version of the SS16 suitable for Brazilian children (SS16-Child). A final version was applied to 51 children alongside a picture identification test (PIT-SS16-Child) to access cognitive abilities involved in the smell identification task. In addition 20 adults performed the same tasks as a comparison group. Results The final adapted SS16-Child was applied to 51 children with a mean age of 9.9 years (range 3-18 years, SD=4.25 years), of which 68.3% were girls. There was an independent effect of age (p<0.05) and PIT-SS16-Child (p<0.001) on the performance on the SS16-Child, and older children reached the ceiling for scoring in the cognitive and olfactory test. Pre-school children had difficulties identifying items of the test. Discussion/Conclusions A cross-culturally adapted version of the SS16 can be used to test olfaction in children but interpretation of the results must take age and cognitive abilities into consideration. PMID:26267145

  3. Test-Retest Reliability and Standard Error of Measurement for the Test of Variables of Attention (T.O.V.A.) With Healthy School-Age Children

    ERIC Educational Resources Information Center

    Leark, Robert A.; Wallace, Denise R.; Fitzgerald, Robert

    2004-01-01

    Test-retest reliability of the Test of Variables of Attention (T.O.V.A.) was investigated in two studies using two different time intervals: 90 min and 1 week (plus or minus 2 days). To investigate the 90-min reliability, 31 school-age children (M = 10 years, SD = 2.66) were administered the T.O.V.A. then read ministered the test 90 min afterward.…

  4. Solid Propulsion Systems, Subsystems, and Components Service Life Extension

    NASA Technical Reports Server (NTRS)

    Hundley, Nedra H.; Jones, Connor

    2011-01-01

    The service life extension of solid propulsion systems, subsystems, and components will be discussed based on the service life extension of the Space Transportation System Reusable Solid Rocket Motor (RSRM) and Booster Separation Motors (BSM). The RSRM is certified for an age life of five years. In the aftermath of the Columbia accident there were a number of motors that were approaching the end of their five year service life certification. The RSRM Project initiated an assessment to determine if the service life of these motors could be extended. With the advent of the Constellation Program, a flight test was proposed that would utilize one of the RSRMs which had been returned from the launch site due to the expiration of its five year service life certification and twelve surplus Chemical Systems Division BSMs which had exceeded their eight year service life. The RSRM age life tracking philosophy which establishes when the clock starts for age life tracking will be described. The role of the following activities in service life extension will be discussed: subscale testing, accelerated aging, dissecting full scale aged hardware, static testing full scale aged motors, data mining industry data, and using the fleet leader approach. The service life certification and extension of the BSMs will also be presented.

  5. The CAST (Childhood Asperger Syndrome Test): Preliminary Development of a UK Screen for Mainstream Primary-School-Age Children.

    ERIC Educational Resources Information Center

    Scott, Fiona J.; Baron-Cohen, Simon; Bolton, Patrick; Brayne, Carol

    2002-01-01

    This article describes a pilot and follow-up study of the development of a screening test for Asperger Syndrome (AS) and relates social and communication conditions in children aged 4-11. Results suggest that the Childhood Asperger Syndrome Test may be useful for identifying children at risk for AS and related conditions, in a mainstream…

  6. The Impact of Retrieval Processes, Age, General Achievement Level, and Test Scoring Scheme for Children's Metacognitive Monitoring and Controlling

    ERIC Educational Resources Information Center

    Krebs, Saskia Susanne; Roebers, Claudia Maria

    2012-01-01

    This multi-phase study examined the influence of retrieval processes on children's metacognitive processes in relation to and in interaction with achievement level and age. First, N = 150 9/10- and 11/12-year old high and low achievers watched an educational film and predicted their test performance. Children then solved a cloze test regarding the…

  7. The effect of shared responsibility and competition in perceptual games: a test of a cognitive game-theoretic extension of signal-detection theory.

    PubMed

    Gopher, D; Itkin-Webman, T; Erev, I; Meyer, J; Armony, L

    2000-02-01

    Perceptual decisions are often made in complex social settings in which distinct observers can affect each other. To address such situations, I. Erev, D. Gopher, R. Itkin, and Y. Greenshpan (1995) proposed a formal extension of signal-detection theory and a descriptive modification of the extended theory. The current article presents 2 experiments that were designed to test these models in the context of repeated 2-person perceptual safety games. In both experiments, pairs of participants performed a simulation of an industrial-production process under distinct payoff rules. Each participant had to try to produce as much as possible while avoiding costly accidents. In line with the descriptive model's predictions, the results showed a slow adjustment to the incentive structure that can be approximated by a reinforcement learning process among different perceptual cutoff strategies. Providing players with prior information about the game had an initial effect but did not alter the pattern of the results. PMID:10696621

  8. Multivariate Analyses and Classification of Inertial Sensor Data to Identify Aging Effects on the Timed-Up-and-Go Test

    PubMed Central

    Vervoort, Danique; Vuillerme, Nicolas; Kosse, Nienke; Hortobágyi, Tibor; Lamoth, Claudine J. C.

    2016-01-01

    Many tests can crudely quantify age-related mobility decrease but instrumented versions of mobility tests could increase their specificity and sensitivity. The Timed-up-and-Go (TUG) test includes several elements that people use in daily life. The test has different transition phases: rise from a chair, walk, 180° turn, walk back, turn, and sit-down on a chair. For this reason the TUG is an often used test to evaluate in a standardized way possible decline in balance and walking ability due to age and or pathology. Using inertial sensors, qualitative information about the performance of the sub-phases can provide more specific information about a decline in balance and walking ability. The first aim of our study was to identify variables extracted from the instrumented timed-up-and-go (iTUG) that most effectively distinguished performance differences across age (age 18–75). Second, we determined the discriminative ability of those identified variables to classify a younger (age 18–45) and older age group (age 46–75). From healthy adults (n = 59), trunk accelerations and angular velocities were recorded during iTUG performance. iTUG phases were detected with wavelet-analysis. Using a Partial Least Square (PLS) model, from the 72-iTUG variables calculated across phases, those that explained most of the covariance between variables and age were extracted. Subsequently, a PLS-discriminant analysis (DA) assessed classification power of the identified iTUG variables to discriminate the age groups. 27 variables, related to turning, walking and the stand-to-sit movement explained 71% of the variation in age. The PLS-DA with these 27 variables showed a sensitivity and specificity of 90% and 85%. Based on this model, the iTUG can accurately distinguish young and older adults. Such data can serve as a reference for pathological aging with respect to a widely used mobility test. Mobility tests like the TUG supplemented with smart technology could be used in clinical

  9. Multivariate Analyses and Classification of Inertial Sensor Data to Identify Aging Effects on the Timed-Up-and-Go Test.

    PubMed

    Vervoort, Danique; Vuillerme, Nicolas; Kosse, Nienke; Hortobágyi, Tibor; Lamoth, Claudine J C

    2016-01-01

    Many tests can crudely quantify age-related mobility decrease but instrumented versions of mobility tests could increase their specificity and sensitivity. The Timed-up-and-Go (TUG) test includes several elements that people use in daily life. The test has different transition phases: rise from a chair, walk, 180° turn, walk back, turn, and sit-down on a chair. For this reason the TUG is an often used test to evaluate in a standardized way possible decline in balance and walking ability due to age and or pathology. Using inertial sensors, qualitative information about the performance of the sub-phases can provide more specific information about a decline in balance and walking ability. The first aim of our study was to identify variables extracted from the instrumented timed-up-and-go (iTUG) that most effectively distinguished performance differences across age (age 18-75). Second, we determined the discriminative ability of those identified variables to classify a younger (age 18-45) and older age group (age 46-75). From healthy adults (n = 59), trunk accelerations and angular velocities were recorded during iTUG performance. iTUG phases were detected with wavelet-analysis. Using a Partial Least Square (PLS) model, from the 72-iTUG variables calculated across phases, those that explained most of the covariance between variables and age were extracted. Subsequently, a PLS-discriminant analysis (DA) assessed classification power of the identified iTUG variables to discriminate the age groups. 27 variables, related to turning, walking and the stand-to-sit movement explained 71% of the variation in age. The PLS-DA with these 27 variables showed a sensitivity and specificity of 90% and 85%. Based on this model, the iTUG can accurately distinguish young and older adults. Such data can serve as a reference for pathological aging with respect to a widely used mobility test. Mobility tests like the TUG supplemented with smart technology could be used in clinical practice

  10. Effects of minimum legal drinking age on alcohol and marijuana use: evidence from toxicological testing data for fatally injured drivers aged 16 to 25 years

    PubMed Central

    Keyes, Katherine M; Brady, Joanne E; Li, Guohua

    2015-01-01

    Background Alcohol and marijuana are among the most commonly used drugs by adolescents and young adults. The question of whether these two drugs are substitutes or complements has important implications for public policy and prevention strategies, especially as laws regarding the use of marijuana are rapidly changing. Methods Data were drawn from fatally injured drivers aged 16 to 25 who died within 1 h of the crash in nine states with high rates of toxicology testing based from 1999 to 2011 on the Fatality Analysis Reporting System (N = 7,191). Drug tests were performed using chromatography and radioimmunoassay techniques based on blood and/or urine specimens. Relative risk regression and Joinpoint permutation analysis were used. Results Overall, 50.5% of the drivers studied tested positive for alcohol or marijuana. Univariable relative risk modeling revealed that reaching the minimum legal drinking age was associated with a 14% increased risk of alcohol use (RR = 1.14, 95% CI: 1.02 to 1.28), a 24% decreased risk of marijuana use (RR = 0.76, 95% CI: 0.53 to 1.10), and a 22% increased risk of alcohol plus marijuana use (RR=1.22, 95% CI: 0.90 to 1.66). Joinpoint permutation analysis indicated that the prevalence of alcohol use by age is best described by two slopes, with a change at age 21. There was limited evidence for a change at age 21 for marijuana use. Conclusions These results suggest that among adolescents and young adults, increases in alcohol availability after reaching the MLDA have marginal effect on marijuana use. PMID:26301177

  11. Clinimetric Testing in Mexican Elders: Associations with Age, Gender, and Place of Residence

    PubMed Central

    Tavano-Colaizzi, Lorena; Arroyo, Pedro; Loria, Alvar; Pérez-Lizaur, Ana Bertha; Pérez-Zepeda, Mario Ulises

    2014-01-01

    Aim: To evaluate the ability of five clinimetric instruments to discriminate between subjects >60 years of age living at home versus those living in a residency. Methods: Trained nutritionists applied five instruments (cognition/depression/functionality/nutrition/appetite) to 285 subjects with majorities of women (64%), aged <80 years (61%), and home residents (54%). Results: Multivariable regression models were generated for each instrument using age, gender, and residency as independent variables. Age was associated with worsening scores in the five instruments whereas residency showed association in three instruments, and gender in two. Score-age regressions by place of residency showed differences suggesting that Mundet residents had increasingly worse scores with increasing age than home dwellers for cognition, depression, and nutrition. Also, living at home prevented the worsening of depression with increasing age. In contrast, functionality and appetite deteriorated at a similar rate for home and Mundet residents suggesting an inability of these two instruments to discriminate between settings. Score-age regressions by gender suggested that males have less cognitive problems at 60 and 80 years of age but not at 100 years, and better appetite than women at all ages. Conclusion: Increasing age proved to be associated to worsening scores in the five instruments but only three were able to detect differences according to setting. An interesting observation was that living at home appeared to prevent the depression increase with increasing age seen in Mundet residents. PMID:25593910

  12. Testing Models of Psychopathology in Preschool-aged Children Using a Structured Interview-based Assessment

    PubMed Central

    Dougherty, Lea R.; Bufferd, Sara J.; Carlson, Gabrielle A.; Klein, Daniel N.

    2014-01-01

    A number of studies have found that broadband internalizing and externalizing factors provide a parsimonious framework for understanding the structure of psychopathology across childhood, adolescence, and adulthood. However, few of these studies have examined psychopathology in young children, and several recent studies have found support for alternative models, including a bi-factor model with common and specific factors. The present study used parents’ (typically mothers’) reports on a diagnostic interview in a community sample of 3-year old children (n=541; 53.9 % male) to compare the internalizing-externalizing latent factor model with a bi-factor model. The bi-factor model provided a better fit to the data. To test the concurrent validity of this solution, we examined associations between this model and paternal reports and laboratory observations of child temperament. The internalizing factor was associated with low levels of surgency and high levels of fear; the externalizing factor was associated with high levels of surgency and disinhibition and low levels of effortful control; and the common factor was associated with high levels of surgency and negative affect and low levels of effortful control. These results suggest that psychopathology in preschool-aged children may be explained by a single, common factor influencing nearly all disorders and unique internalizing and externalizing factors. These findings indicate that shared variance across internalizing and externalizing domains is substantial and are consistent with recent suggestions that emotion regulation difficulties may be a common vulnerability for a wide array of psychopathology. PMID:24652485

  13. Percentile Values for Running Sprint Field Tests in Children Ages 6-17 Years: Influence of Weight Status

    ERIC Educational Resources Information Center

    Castro-Pinero, Jose; Gonzalez-Montesinos, Jose Luis; Keating, Xiaofen D.; Mora, Jesus; Sjostrom, Michael; Ruiz, Jonatan R.

    2010-01-01

    The aim of this study was to provide percentile values for six different sprint tests in 2,708 Spanish children (1,234 girls) ages 6-17.9 years. We also examined the influence of weight status on sprint performance across age groups, with a focus on underweight and obese groups. We used the 20-m, 30-m, and 50-m running sprint standing start and…

  14. Comparison of Different Cells of Haematococcus pluvialis Reveals an Extensive Acclimation Mechanism during its Aging Process: From a Perspective of Photosynthesis

    PubMed Central

    Gu, Wenhui; Xie, Xiujun; Gao, Shan; Zhou, Wei; Pan, Guanghua; Wang, Guangce

    2013-01-01

    Both biomass dominated green vegetative cells (GV) and astaxanthin-dominated orange resting cells (OR) affect the final astaxanthin yield in industry. Examination of Haematococcus pluvialis revealed that the OR cells greatly varied from the GV cells at both cellular and subcellular levels. In particular, the thylakoid membranes in the OR were disassembled and fragmented. Furthermore, the OR conserved most of the photosynthetic pigments, with elevated concentrations of violaxanthin, antheraxanthin, and neoxanthin. Notably, moderate photosynthesis was detected in OR, even though most of the thylakoid membranes were disassembled, when compared with those in the GV. However, the energy distribution pattern between photosystem I and II (PSI and PSII) in the OR favored PSI, which was also confirmed by 77-K fluorescence. As zeaxanthin was not detected in the OR, we attribute the acclimation role to astaxanthin, instead of xanthophyll cycle. Additionally, proteomic-scale comparison analysis of thylakoids of the OR and GV indicated no photosynthetically remarkable variations. However, an extensive acclimation mechanism of H. pluvialis was proposed, in which proteins in thylakoid of GV were noted to be involved in biomass accumulation and those in OR were involved in stress response. Conclusions of the comparative analysis might provide some physiological background of OR for astaxanthin production by using H. pluvialis. PMID:23922648

  15. Comparison of different cells of Haematococcus pluvialis reveals an extensive acclimation mechanism during its aging process: from a perspective of photosynthesis.

    PubMed

    Gu, Wenhui; Xie, Xiujun; Gao, Shan; Zhou, Wei; Pan, Guanghua; Wang, Guangce

    2013-01-01

    Both biomass dominated green vegetative cells (GV) and astaxanthin-dominated orange resting cells (OR) affect the final astaxanthin yield in industry. Examination of Haematococcus pluvialis revealed that the OR cells greatly varied from the GV cells at both cellular and subcellular levels. In particular, the thylakoid membranes in the OR were disassembled and fragmented. Furthermore, the OR conserved most of the photosynthetic pigments, with elevated concentrations of violaxanthin, antheraxanthin, and neoxanthin. Notably, moderate photosynthesis was detected in OR, even though most of the thylakoid membranes were disassembled, when compared with those in the GV. However, the energy distribution pattern between photosystem I and II (PSI and PSII) in the OR favored PSI, which was also confirmed by 77-K fluorescence. As zeaxanthin was not detected in the OR, we attribute the acclimation role to astaxanthin, instead of xanthophyll cycle. Additionally, proteomic-scale comparison analysis of thylakoids of the OR and GV indicated no photosynthetically remarkable variations. However, an extensive acclimation mechanism of H. pluvialis was proposed, in which proteins in thylakoid of GV were noted to be involved in biomass accumulation and those in OR were involved in stress response. Conclusions of the comparative analysis might provide some physiological background of OR for astaxanthin production by using H. pluvialis. PMID:23922648

  16. Extensive protein hydrolysate formula effectively reduces regurgitation in infants with positive and negative challenge tests for cow’s milk allergy

    PubMed Central

    Vandenplas, Y; De Greef, E

    2014-01-01

    Aim Cow’s milk protein allergy (CMPA) is treated using an elimination diet with an extensive protein hydrolysate. We explored whether a thickened or nonthickened version was best for infants with suspected CMPA, which commonly causes regurgitation/vomiting. Methods Diagnosis of CMPA was based on a positive challenge test. We compared the efficacy of two casein extensive hydrolysates (eCH), a nonthickened version (NT-eCH) and a thickened version (T-eCH), using a symptom-based score covering regurgitation, crying, stool consistency, eczema, urticarial and respiratory symptoms. Results A challenge was performed in 52/72 infants with suspected CMPA and was positive in 65.4%. All confirmed CMPA cases tolerated eCH. The symptom-based score decreased significantly in all infants within a month, and the highest reduction was in those with confirmed CMPA. Regurgitation was reduced in all infants (6.4 ± 3.2–2.8 ± 2.9, p < 0.001), but fell more with the T-eCH (−4.2 ± 3.2 regurgitations/day vs. −3.0 ± 4.5, ns), especially in infants with a negative challenge (−3.9 ± 4.0 vs. −1.9 ± 3.4, ns). Conclusion eCH fulfilled the criteria for a hypoallergenic formula, and the NT-eCH and T-eCH formulas both reduced CMPA symptoms. The symptom-based score is useful for evaluating how effective dietary treatments are for CMPA. PMID:24575806

  17. Test of visuospatial construction: Validity evidence in extremely low birth weight and late preterm children at early school age.

    PubMed

    Rider, G Nicole; Weiss, Brandi A; McDermott, Adam T; Hopp, Crista A; Baron, Ida Sue

    2016-01-01

    The Test of Visuospatial Construction (TVSC), a measure of visuoconstruction that does not rely on upper extremity motor response or written production, was administered to extremely low birth weight (ELBW), late preterm (LPT), and term participants at preschool (n = 355) and kindergarten (n = 265) ages. TVSC showed statistically significant weak-to-moderate positive correlations (age 3: r = .118-.303; age 6: r = .138-.348) with Developmental VMI, Differential Ability Scales-II Copying, Matrices, and Pattern Construction subtests, Baron-Hopkins Board Test, and the Purdue Pegboard. One-way ANOVA indicated ELBW performed worse than Term (p = .044) on visuospatial construction at age 3 with a small-to-medium effect size (d = -0.43). No other statistically significant differences were found at age 3 on the TVSC (ELBW/LPT: p = .608, d = -0.17; LPT/Term: p = .116, d = -0.31). At age 6, ELBW participants performed worse than LPT participants (p = .027) and Term participants (p = .012); LPT participants did not differ from Term participants. Small effect sizes at age 3 (ELBW < LPT, d = -0.17; ELBW < Term, d = -0.43) were notably larger at age 6 (ELBW < LPT, d = -0.42; ELBW < Term, d = -0.53). Important practical differences showing LPT participants performed below Term participants (d = -0.31) at age 3 were no longer evident at age 6 (d = -0.097). These findings provide preliminary evidence of TVSC validity supporting its use to detect neuropsychological impairment and to recommend appropriate interventions in young preterm children. PMID:25952145

  18. Testing evolutionary models of senescence in a natural population: age and inbreeding effects on fitness components in song sparrows

    PubMed Central

    Keller, L.F; Reid, J.M; Arcese, P

    2008-01-01

    Mutation accumulation (MA) and antagonistic pleiotropy (AP) have each been hypothesized to explain the evolution of ‘senescence’ or deteriorating fitness in old age. These hypotheses make contrasting predictions concerning age dependence in inbreeding depression in traits that show senescence. Inbreeding depression is predicted to increase with age under MA but not under AP, suggesting one empirical means by which the two can be distinguished. We use pedigree and life-history data from free-living song sparrows (Melospiza melodia) to test for additive and interactive effects of age and individual inbreeding coefficient (f) on fitness components, and thereby assess the evidence for MA. Annual reproductive success (ARS) and survival (and therefore reproductive value) declined in old age in both sexes, indicating senescence in this short-lived bird. ARS declined with f in both sexes and survival declined with f in males, indicating inbreeding depression in fitness. We observed a significant age×f interaction for male ARS (reflecting increased inbreeding depression as males aged), but not for female ARS or survival in either sex. These analyses therefore provide mixed support for MA. We discuss the strengths and limitations of such analyses and therefore the value of natural pedigreed populations in testing evolutionary models of senescence. PMID:18211879

  19. Longitudinal Study of Performance on the Ruff Figural Fluency Test in Persons Aged 35 Years or Older

    PubMed Central

    van Eersel, Marlise E. A.; Joosten, Hanneke; Koerts, Janneke; Gansevoort, Ron T.; Slaets, Joris P. J.; Izaks, Gerbrand J.

    2015-01-01

    The Ruff Figural Fluency Test (RFFT) is a cognitive test to measure executive function. Longitudinal studies have shown that repeated testing improves performance on the RFFT. Such a practice effect may hinder the interpretation of test results in a clinical setting. Therefore, we investigated the longitudinal performance on the RFFT in persons aged 35–82 years. Performance on the RFFT was measured three times over an average follow-up period of six years in 2,515 participants of the Prevention of REnal and Vascular ENd-stage Disease (PREVEND) study in Groningen, the Netherlands: 53% men; mean age (SD), 53 (10) years. The effect of consecutive measurements on performance on the RFFT was investigated with linear multilevel regression models that also included age, gender, educational level and the interaction term consecutive measurement number x age as independent variables. It was found that the mean (SD) number of unique designs on the RFFT increased from 73 (26) at the first measurement to 79 (27) at the second measurement and to 83 (26) at the third measurement (p<0.001). However, the increase per consecutive measurement number was negatively associated with age and decreased with 0.23 per one-year increment of age (p<0.001). The increase per consecutive measurement number was not dependent on educational level. Similar results were found for the median (IQR) number of perseverative errors which showed a small but statistically significant increase with repeating testing: 7 (3–13) at the first measurement, 7 (4–14) at the second measurement and 8 (4–15) at the third measurement (ptrend = 0.002). In conclusion, the performance on the RFFT improved by repeating the test over an average follow-up period of three to six years. This practice effect was the largest in young adults and not dependent on educational level. PMID:25799403

  20. Communication & Aging.

    ERIC Educational Resources Information Center

    Arnold, William E.

    This extensive bibliography contains more than 1,800 entries about communication and aging. The citations include journal articles, unpublished papers, speeches, dissertations, research studies, and books that relate aging and the aged to a variety of topics, including the following: physiological deterioration, socialization, political…

  1. A test of the 40Ar/39Ar age spectrum technique on some terrestrial materials

    USGS Publications Warehouse

    Lanphere, M.A.; Brent, Dalrymple G.

    1971-01-01

    40Ar/39Ar age spectra were determined for 10 terrestrial rock and mineral samples whose geologic history is known from independent evidence. The spectra for six mineral and whole rock samples, including biotite, feldspar, hornblende, muscovite, and granodiorite, that have experienced post-crystallization heating did not reveal the age of crystallization in any obvious way. Minima in the spectra, however, give reasonable maximum ages for reheating and high-temperature maxima can be interpreted as minimum crystallization ages. High-temperature ages of microcline and albite that have not been reheated are approximately 10% younger than the known crystallization age. Apparently there are no domains in these feldspars that have retained radiogenic 40Ar quantitatively. Spectra from two diabase samples that contain significant quantities of excess argon might mistakenly be interpreted as spectra from reheated samples and do not give the age of emplacement. The 40Ar/39Ar age spectrum technique may be a potentially valuable tool for the study of geologic areas with complex histories, but the interpretation of age spectra from terrestrial samples seems to be more difficult than suggested by some previous studies. ?? 1971.

  2. Functional equivalence of the National Adult Reading Test (NART) and Schonell reading tests and NART norms in the Dynamic Analyses to Optimise Ageing (DYNOPTA) project.

    PubMed

    Kiely, Kim M; Luszcz, Mary A; Piguet, Olivier; Christensen, Helen; Bennett, Hayley; Anstey, Kaarin J

    2011-04-01

    This study investigates the functional equivalence of two measures of irregular word pronunciation--National Adult Reading Test (NART) and Schonell--which are popular instruments used to assess verbal neurocognitive functioning and to estimate premorbid IQ. We report norms for the NART in a pooled sample from 3 Australian population-based studies of adults aged 65-103 years. Norms were stratified by sex and age left school in 5-year age groups. The NART and the Schonell had a strong linear relation, allowing for the imputation of NART scores based on Schonell performance within 1 study. Neither measure was sensitive to the effects of sex after adjusting for the effects of age and education. Early school leavers performed worse on both measures. Data pooling enables greater precision and improved generalizability of NART norms than do methods that use single older adult samples. PMID:21132592

  3. Characterization and testing of a new environmental chamber designed for emission aging studies

    NASA Astrophysics Data System (ADS)

    Leskinen, A.; Yli-Pirilä, P.; Kuuspalo, K.; Sippula, O.; Jalava, P.; Hirvonen, M.-R.; Jokiniemi, J.; Virtanen, A.; Komppula, M.; Lehtinen, K. E. J.

    2014-06-01

    A 29 m3 Teflon chamber, designed for aging studies of combustion aerosols, at the University of Eastern Finland is described and characterized. The chamber belongs to a research facility, called Ilmari, where small-scale combustion devices, a dynamometer for vehicle exhaust studies, dilution systems, the chamber, as well as cell and animal exposure devices are side by side under the same roof. The small surface-to-volume ratio of the chamber enables reasonably long experiment times, with particle wall loss rate constants of 0.088, 0.080, 0.045, and 0.040 h-1 for polydisperse, 50, 100, and 200 nm monodisperse aerosols, respectively. The NO2 photolysis rate can be adjusted from zero to 0.62 min-1. The irradiance spectrum is centered at 365 nm and the maximum irradiance, produced by 160 blacklight lamps, is 29.7 W m-2, which corresponds to the UV irradiance in Central Finland at noon on a sunny day in the midsummer. The temperature inside the chamber is uniform and can be kept at 25 ± 1 °C when half of the blacklights are on. The chamber is kept in an overpressure with a moving top frame, which prevents sample dilution and contamination from entering the chamber during an experiment. The functionality of the chamber was tested with oxidation experiments of toluene, resulting in secondary organic aerosol (SOA) yields of 33-44%, depending on the initial conditions, such as the NOx concentration. The highest gaseous oxidation product yields of 14.4-19.5% were detected with ions corresponding to 2-butenedial (m/z 73.029) and 4-oxo-2-pentenal (m/z 99.044). Overall, reasonable yields of SOA and gaseous reaction products, comparable to those obtained in other laboratories, were obtained.

  4. FIELD TEST INSTRUCTION 100-NR-2 OPERABLE UNIT DESIGN OPTIMIZATION STUDY FOR SEQUESTRATION OF SR-90 SATURATED ZONE APATITE PERMEABLE REACTIVE BARRIER EXTENSION

    SciTech Connect

    BOWLES NA

    2010-10-06

    The objective of this field test instruction is to provide technical guidance for aqueous injection emplacement of an extension apatite permeable reactive barrier (PRE) for the sequestration of strontium-90 (Sr-90) using a high concentration amendment formulation. These field activities will be conducted according to the guidelines established in DOE/RL-2010-29, 100-NR-2 Design Optimization Study, hereafter referred to as the DOS. The DOS supports the Federal Facility Agreement Consent Order (EPA et al., 1989), Milestone M-16-06-01, and 'Complete Construction of a Permeable Reactive Barrier at 100-N.' Injections of apatite precursor chemicals will occur at an equal distance intervals on each end of the existing PRE to extend the PRB from the existing 91 m (300 ft) to at least 274 m (900 ft). Field testing at the 100-N Area Apatite Treatability Test Site, as depicted on Figure 1, shows that the barrier is categorized by two general hydrologic conceptual models based on overall well capacity and contrast between the Hanford and Ringold hydraulic conductivities. The upstream portion of the original barrier, shown on Figure 1, is characterized by relatively low overall well specific capacity. This is estimated from well development data and a lower contrast in hydraulic conductivity between the Hanford formation and Ringold Formations. Comparison of test results from these two locations indicate that permeability contrast between the Hanford formation and Ringold Formation is significantly less over the upstream one-third of the barrier. The estimated hydraulic conductivity for the Hanford formation and Ringold Formation over the upstream portion of the barrier based on observations during emplacement of the existing 91 m (300 ft) PRB is approximately 12 and 10 m/day (39 and 32 ft/day), respectively (PNNL-17429). However, these estimates should be used as a rough guideline only, as significant variability in hydraulic conductivity is likely to be observed in the

  5. Accelerated ageing in testing bricks used in the conservation of historic buildings

    NASA Astrophysics Data System (ADS)

    Pavlendová, Gabriela; Podoba, Rudolf; Baník, Ivan

    2014-11-01

    The effect of accelerated climate ageing on historical bricks in the laboratory is investigated in the paper. Differences in thermal properties are experimentally determined and studied before and after bricks exposure to climate ageing, which consists of 60 freeze-thaw cycles. For measuring thermal conductivity, diffusivity and specific heat, pulse method is used.

  6. Testing principle working mechanisms of the health action process approach for subjective physical age groups.

    PubMed

    Wienert, Julian; Kuhlmann, Tim; Fink, Sebastian; Hambrecht, Rainer; Lippke, Sonia

    2016-01-01

    This study investigated differences in social-cognitive predictors and self-regulatory planning, as proposed by the health action process approach (HAPA), across three different subjective physical age groups for physical activity. With a cross-sectional design, 521 participants across the chronological age span from 25 to 86 years (M = 48.79; SD = 12.66) were separated into three groups: those who feel physically younger than they are in terms of chronological age, the same perceived and chronological age, and feeling physically older compared to their chronological age. Participants were assessed regarding their perceived vulnerability, outcome expectancies, general intentions, planning, self-efficacy, and stages of physical activity (non-intenders, intenders, and actors). Data were analysed via mean comparison and multigroup structural equation modelling. Mean differences for all but one construct were eminent in all groups, generally showing that those feeling physically younger also report better social-cognitive predictors of physical activity (e.g. lower perceived vulnerability) in comparison to those who feel the same age or older. The model showed that basic working mechanisms of the HAPA can be applied to all groups. With that, the results provide for the first time evidence that principle working mechanism of the HAPA can be applied to all subjective physical age groups. These may be used to tailor health promoting interventions according to participants' needs as a more suitable proxy than chronological age. PMID:26967593

  7. Effects of Age and Schooling on 22 Ability and Achievement Tests

    ERIC Educational Resources Information Center

    Gambrell, James Lamar

    2013-01-01

    Although much educational research has investigated the relative effectiveness of different educational interventions and policies, little is known about the absolute net benefits of K-12 schooling independent of growth due to chronological age and out-of-school experience. The nearly universal policy of age tracking in schools makes this a…

  8. A New Agility Test for Adults: Its Test-Retest Reliability and Minimal Detectable Change in Untrained Women and Men Aged 28-55.

    PubMed

    Manderoos, Sirpa A; Vaara, Mariitta E; Mäki, P Juhani; Mälkiä, Esko A; Aunola, Sirkka K; Karppi, Sirkka-Liisa

    2016-08-01

    Manderoos, SA, Vaara, ME, Mäki, PJ, Mälkiä, EA, Aunola, SK, and Karppi, S-L. A new agility test for adults: its test-retest reliability and minimal detectable change in untrained women and men aged 28-55. J Strength Cond Res 30(8): 2226-2234, 2016-The aims of this study were to present a new Agility Test for Adults (ATA), to investigate its test-retest reliability and to quantify minimal detectable change at the 95% confidence interval (MDC95). Both the relative and absolute reliabilities were evaluated. Altogether 52 healthy untrained volunteers (25 women: age 43.3 ± 6.6 years; 27 men: age 42.8 ± 7.2 years) were recruited into the study. The subjects performed 3 ATA tests repeated after 2 different intervals: the first test session was baseline, session 2 was a week later, and session 3 was half an hour after session 2. The intraclass correlation coefficient and the SEM of the performance time of ATA were 0.91 and 0.27 seconds (same day), 0.94 and 0.20 seconds (1 week) for women, and 0.95, 0.13 seconds, and 0.94, 0.19 seconds for men, respectively. MDC95 was 0.76 seconds (same day) and 0.56 seconds (1 week) for women, and respectively 0.37 and 0.51 seconds for men. The results showed that ATA is stable and reliable when evaluating agility characteristics in untrained adults. The properties of ATA make it appropriate for screening people to find early signs of declined agility and allow possibility to clinicians and physical trainers to monitor true changes in performance time at agility test by applying the knowledge of MDC95 coefficient. Furthermore, ATA can give tips for planning appropriate exercise programes to prevent clumsiness and falls with more serious consequences among aging people. PMID:26705068

  9. HIV Testing Among Young People Aged 16-24 in South Africa: Impact of Mass Media Communication Programs.

    PubMed

    Do, Mai; Figueroa, Maria Elena; Lawrence Kincaid, D

    2016-09-01

    Knowing one's serostatus is critical in the HIV prevention, care and treatment continuum. This study examines the impact of communication programs on HIV testing in South Africa. Data came from 2204 young men and women aged 16-24 who reported to be sexually active in a population based survey. Structural equation modeling was used to test the directions and causal pathways between communication program exposure, HIV testing discussion, and having a test in the last 12 months. Bivariate and multivariate probit regressions provided evidence of exogeneity of communication exposure and the two HIV-related outcomes. One in three sampled individuals had been tested in the last 12 months. Communication program exposure only had an indirect effect on getting tested by encouraging young people to talk about testing. The study suggests that communication programs may create an environment that supports open HIV-related discussions and may have a long-term impact on behavior change. PMID:27102409

  10. Development of a field test for evaluating aerobic fitness in middle-aged adults: validity of a 15-m incremental shuttle walk and run test.

    PubMed

    Mikawa, Kotaro; Senjyu, Hideaki

    2011-01-01

    The purpose of this study was to develop a standardized and externally paced field test (15-m Incremental Shuttle Walk and Run Test [15mISWRT]), incorporating an incremental and progressive structure, to assess aerobic fitness in middle-aged adults. 68 middle-aged men performed three tests in random order between one to two week intervals: 15-m ISWRT, cardiopulmonary exercise test (CPX), and 1500-m fast walk. Variables evaluated were 15-m ISWRT performance (distance completed), VO2max measured by CPX, 1500-m fast walk performance (walking time), and HR response in 15-m ISWRT and 1500-m fast walk. Validity of the 15-m ISWRT was tested by comparing the associations among the 15-m ISWRT performance, VO2max and the 1500-m fast walk performance. Changes in HR response during the 15-m ISWRT and the 1500-m fast walk were also compared. Correlations between each variable were as follows: the correlation between 15- m ISWRT performance and VO2max was very high, r = 0.86 (p < 0.01), the correlation between the 1500-m fast walk and VO2max was r = -0.51 (p < 0.01). HR response during the 15-m ISWRT gently increased initially, whereas HR response during the 1500-m fast walk rapidly increased from the start. In conclusion, our findings indicate that the 15-m ISWRT is valid and safe for evaluating VO2max in middle-aged adults. Key pointsThe 15-m ISWRT is valid and safe for evaluating VO2max in middle-aged adults.In comparison with the 1500-m fast walk, the 15-m ISWRT may be a more favourable field-based assessment of aerobic fitness in the middle-aged adults.The 15-m ISWRT could become a valid means for evaluating aerobic fitness as an alternative to CPX in institutions and situations where CPX is difficult to implement. PMID:24149563

  11. Age constraints on Jerritt Canyon and other Carlin-type gold deposits in the western United States-relationship to mid-Tertiary extension and magmatism

    USGS Publications Warehouse

    Hofstra, A.H.; Snee, L.W.; Rye, R.O.; Folger, H.W.; Phinisey, J.D.; Loranger, R.J.; Dahl, A.R.; Naeser, C.W.; Stein, H.J.; Lewchuk, M.

    1999-01-01

    Carlin-type gold deposits are difficult to date and a wide range of ages has been reported for individual deposits. Therefore, several methods were employed to constrain the age of the gold deposits in the Jerritt Canyon district. Dated igneous rocks with well-documented crosscutting relationships to ore provided the most reliable constraints. K/Ar and 40Ar/39Ar dates on igneous rocks are as follows: andesite dikes 324 Ma, sericitic alteration in andesite dikes 118 Ma, basalt dikes 40.8 Ma, quartz monzonite dikes 39.2 Ma, and calc-alkaline ignimbrites 43.1 to 40.1 Ma. Of these, only the andesite and basalt dikes are clearly altered and mineralized. The gold deposits are, therefore, younger than the 40.8 Ma basalt dikes. The sericitic alteration in the andesite dikes is unrelated to the gold deposits. A number of dating techniques did not work. K/Ar and 40Ar/39Ar dates on mica from mineralized Ordovician to Devonian sedimentary rocks gave misleading results. The youngest date of 149 Ma from the smallest <0.1-??m-size fraction shows that the temperature (120??-260??C) and duration (?) of hydrothermal activity was insufficient to reset preexisting fine-grained micas in the host rocks. The temperature and duration was also insufficient to anneal fission tracks in zircon from Ordovician quartzites as they yield Middle Proterozoic dates in both mineralized and barren samples. Apatites were too small for fission track dating. Hydrothermal sulfides have pronounced crustal osmium isotope signatures (187Os/188Os(initial) = 0.9-3.6) but did not yield a meaningful isochron due to very low Re and Os concentrations and large analytical uncertainties. Paleomagnetic dating techniques failed because the hydrothermal fluids sulfidized nearly all of the iron in the host rocks leaving no remnant magnetism. When published isotopic dates from other Carlin-type deposits in Nevada and Utah are subject to the rigorous evaluation developed for the Jerritt Canyon study, most deposits can be

  12. In vitro activities of sitafloxacin tested alone and in combination with rifampin, colistin, sulbactam, and tigecycline against extensively drug-resistant Acinetobacter baumannii

    PubMed Central

    Dong, Xiaomeng; Chen, Fengzhe; Zhang, Yajun; Liu, Haihong; Liu, Yongjuan; Ma, Lixian

    2015-01-01

    Objectives: To detect the in vitro activities of sitafloxacin alone and in combination with rifampin, colistin, sulbactam, and tigecycline against extensively drug-resistant Acinetobacter baumannii (XDR-A. baumannii). Materials and methods: 24 XDR-A. baumannii strains were isolated from patients’ specimens. Broth microdilution assay was used to determine the minimum inhibitory concentration (MIC) for sitafloxacin, rifampin, colistin, sulbactam, and tigecycline against XDR-A. baumannii strains. The checkerboard microdilution method was used to determine the in vitro activities of sitafloxacin combined with the other four antimicrobial agents. Accordingly, the fractional inhibitory concentration (FIC) and FIC index (FICI) were calculated for each of the combinations. Results: According to our results, when tested alone, the rate of susceptibility for sitafloxacin was 91.67% against XDR-A. baumannii, followed by colistin 62.5%, and then tigecycline 54.17%, rifampin 41.67%. Sulbactam, with a 16.67% rate of susceptibility was the least effective one. On the other hand, when tested in combination, all those three combinations except tigecycline/sitafloxacin revealed remarkable synergistic effects. Colistin/sitafloxacin showed the highest indifference rate. These combination regimens could exert addictive or partially-synergistic effects at the sub-MIC levels against XDR-A. baumannii strains. Conclusion: Sitafloxacin has acceptable in vitro activity against XDR-A. baumannii strains as well as tigecycline, rifampin and colistin. Compared with single drugs, most of the combinations of these antimicrobial agents could exert synergistic and/or partially synergistic and/or addictive effects, which might provide a better alternative when treating XDR-A. baumannii infections. PMID:26221381

  13. 16 CFR Figure 5 to Part 1203 - Location of Test Lines for Helmets Intended for Persons Ages 1 and Older

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Location of Test Lines for Helmets Intended for Persons Ages 1 and Older 5 Figure 5 to Part 1203 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR BICYCLE HELMETS Pt. 1203, Fig....

  14. 16 CFR Figure 5 to Part 1203 - Location of Test Lines for Helmets Intended for Persons Ages 1 and Older

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 2 2013-01-01 2013-01-01 false Location of Test Lines for Helmets Intended for Persons Ages 1 and Older 5 Figure 5 to Part 1203 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR BICYCLE HELMETS Pt. 1203, Fig....

  15. 16 CFR Figure 5 to Part 1203 - Location of Test Lines for Helmets Intended for Persons Ages 1 and Older

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Location of Test Lines for Helmets Intended for Persons Ages 1 and Older 5 Figure 5 to Part 1203 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR BICYCLE HELMETS Pt. 1203, Fig....

  16. Validation of the Spanish Version of the Woodcock-Johnson Mathematics Achievement Tests for Children Aged 6 to 13

    ERIC Educational Resources Information Center

    Diamantopoulou, Sofia; Pina, Violeta; Valero-Garcia, Ana V.; Gonzalez-Salinas, Carmen; Fuentes, Luis J.

    2012-01-01

    This study validated the four mathematics tests of the Spanish version of the Woodcock-Johnson III (WJ-III) Achievement (ACH) battery for use in the first six grades of school in Spain. Developmental effects and gender differences were also examined. Participants were a normal population sample of 424 (216 boys) children aged 6 to 13 years.…

  17. The AVOM: A Model-Derived, Age-Limited, and Modality-Related Test of Intellectual Functioning.

    ERIC Educational Resources Information Center

    Wildman, Robert W.; L'Abate, Luciano

    1979-01-01

    Reviews status of intellectual assessment. The AVOM Test is a potentially useful device. It measures performance in two input channels, auditory and visual, and two output channels, oral and manual. AVOM was administered to elementary school students. Scores increased with age, and other results support potential utility of the device. (Author)

  18. Proton exchange membrane fuel cell model for aging predictions: Simulated equivalent active surface area loss and comparisons with durability tests

    NASA Astrophysics Data System (ADS)

    Robin, C.; Gérard, M.; Quinaud, M.; d'Arbigny, J.; Bultel, Y.

    2016-09-01

    The prediction of Proton Exchange Membrane Fuel Cell (PEMFC) lifetime is one of the major challenges to optimize both material properties and dynamic control of the fuel cell system. In this study, by a multiscale modeling approach, a mechanistic catalyst dissolution model is coupled to a dynamic PEMFC cell model to predict the performance loss of the PEMFC. Results are compared to two 2000-h experimental aging tests. More precisely, an original approach is introduced to estimate the loss of an equivalent active surface area during an aging test. Indeed, when the computed Electrochemical Catalyst Surface Area profile is fitted on the experimental measures from Cyclic Voltammetry, the computed performance loss of the PEMFC is underestimated. To be able to predict the performance loss measured by polarization curves during the aging test, an equivalent active surface area is obtained by a model inversion. This methodology enables to successfully find back the experimental cell voltage decay during time. The model parameters are fitted from the polarization curves so that they include the global degradation. Moreover, the model captures the aging heterogeneities along the surface of the cell observed experimentally. Finally, a second 2000-h durability test in dynamic operating conditions validates the approach.

  19. Relationships between Narrative Language Samples and Norm-Referenced Test Scores in Language Assessments of School-Age Children

    ERIC Educational Resources Information Center

    Ebert, Kerry Danahy; Scott, Cheryl M.

    2014-01-01

    Purpose: Both narrative language samples and norm-referenced language tests can be important components of language assessment for school-age children. The present study explored the relationship between these 2 tools within a group of children referred for language assessment. Method: The study is a retrospective analysis of clinical records from…

  20. Reliability of the Quality of Upper Extremity Skills Test for Children with Cerebral Palsy Aged 2 to 12 Years

    ERIC Educational Resources Information Center

    Thorley, Megan; Lannin, Natasha; Cusick, Anne; Novak, Iona; Boyd, Roslyn

    2012-01-01

    Aim: To investigate reliability of the Quality of Upper Extremity Skills Test (QUEST) scores for children with cerebral palsy (CP) aged 2-12 years. Method: Thirty-one QUESTs from 24 children with CP were rated once by two raters and twice by one rater. Internal consistency of total scores, inter- and intra-rater reliability findings for total,…

  1. THE EFFECT OF AGE AS A VARIABLE ON THE SCORES OF THE HARRIS-GOODENOUGH DRAWING TEST OF EDUCABLE RETARDATES.

    ERIC Educational Resources Information Center

    LEVY, IRWIN S.

    IN ORDER TO DETERMINE THE RELIABILITY OF PERFORMANCE OF RETARDED ADOLESCENTS ON THE HARRIS REVISION OF THE GOODENOUGH DRAW-A-MAN TEST (DAM) AND WHETHER THE DECLINE IN PERFORMANCE WHICH OCCURS IN NORMAL ADOLESCENTS AT THE MID-TEENS ALSO OCCURS WITH RETARDED ADOLESCENTS, 213 MALE AND 130 FEMALE SUBJECTS, AGED 11-20 YEARS AND WITH IQ'S OF 56-72, IN…

  2. Effects of timing, sex, and age on site-specific gastrointestinal permeability testing in children and adults

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Measurement of gastrointestinal permeability is commonly used in research and often used clinically. Despite its utility, little is known about sugar excretion timeframes or the potential effects of age and sex on GI permeability testing. We seek to determine the timeframes of sugar excretion and th...

  3. "Are vocabulary tests measurement invariant between age groups? An item response analysis of three popular tests": Correction to Fox, Berry, and Freeman (2014).

    PubMed

    2016-08-01

    Reports an error in "Are vocabulary tests measurement invariant between age groups? An item response analysis of three popular tests" by Mark C. Fox, Jane M. Berry and Sara P. Freeman (, 2014[Dec], Vol 29[4], 925-938). In the article, unneeded zeros were inadvertently included at the beginnings of some numbers in Tables 1-4. In addition, the right column in Table 4 includes three unnecessary zeros after asterisks. (The following abstract of the original article appeared in record .) Relatively high vocabulary scores of older adults are generally interpreted as evidence that older adults possess more of a common ability than younger adults. Yet, this interpretation rests on empirical assumptions about the uniformity of item-response functions between groups. In this article, we test item response models of differential responding against datasets containing younger-, middle-aged-, and older-adult responses to three popular vocabulary tests (the Shipley, Ekstrom, and WAIS-R) to determine whether members of different age groups who achieve the same scores have the same probability of responding in the same categories (e.g., correct vs. incorrect) under the same conditions. Contrary to the null hypothesis of measurement invariance, datasets for all three tests exhibit substantial differential responding. Members of different age groups who achieve the same overall scores exhibit differing response probabilities in relation to the same items (differential item functioning) and appear to approach the tests in qualitatively different ways that generalize across items. Specifically, younger adults are more likely than older adults to leave items unanswered for partial credit on the Ekstrom, and to produce 2-point definitions on the WAIS-R. Yet, older adults score higher than younger adults, consistent with most reports of vocabulary outcomes in the cognitive aging literature. In light of these findings, the most generalizable conclusion to be drawn from the cognitive aging

  4. The effect of age on result of straight leg raising test in patients suffering lumbar disc herniation and sciatica

    PubMed Central

    Tabesh, Homayoun; Tabesh, Ariyan; Fakharian, Esmaeil; Fazel, Mohammadreza; Abrishamkar, Saeid

    2015-01-01

    Background: Ninety percent of all people sometimes during their lives experience low back pain, and 30-40% develops radicular leg pain with the sciatica characteristics. Although for clinical diagnosis of lumbar disc herniation (LDH) straight leg raising (SLR) test in 85-90% of cases indicates LDH, but in our practice with LDH patients this test is frequently negative despite radicular leg pain due to LDH. Hence, we decided to evaluate this test in LDH in different age groups. Materials and Methods: All patients with leg pain referring to neurosurgery clinic were enrolled. Those with a history of pain other than sciatica excluded and SLR test and magnetic resonance imaging (MRI) of the lumbosacral spine performed. The patients with negative MRI findings excluded and finally 269 patients with true sciatica and positive MRI were included. SLR tests were performed for different age groups. Results: Of 269 patients, 167 were male. The age range was 16-80 years. The most involved levels were L5-S1 (47%) and L4-L5 (42%), respectively. The rate of positive SLR result, which was 100%, 87% and 82% for 10-19, 20-29 and 30-39 years age group respectively. With an increment of age, the rate of positive test regularly declined. The chance of positive SLR in men is 1.3 times the women (odds ratio [OR] 2.4; 95% confidence interval [CI] = 1.265-4.557; P = 0.007). Increasing the age has suppression effect in positivity of SLR so that for each 1-year the chance of SLR become 0.27 times less to become positive and this is also statically meaningful (OR = 0.271;95% CI = 0.188-0.391; P,0.001). The chance of positive SLR for patients under 60 is 5.4 folds more than patients above 60 years old (OR = 5.4; 95% CI = 4-8.3; P, 0.001). Conclusion: Age, sex (male), and disk level had statistically the effect on SLR positive test. PMID:25983767

  5. Age-related changes in human vestibulo-ocular and optokinetic reflexes: Pseudorandom rotation tests

    NASA Technical Reports Server (NTRS)

    Peterka, R. J.; Black, F. O.; Schoenhoff, M. B.

    1989-01-01

    The dynamic response properties of horizontal vestibulo-ocular reflex (VOR) and optokinetic reflex (OKR) were characterized in 216 human subjects ranging in age from 7 to 81 years. The object of this cross-sectional study was to determine the effects of aging on VOR and OKR reflex dynamics, and to identify the distributions of parameters which describe VOR and OKR responses to pseudorandom stimuli in a putatively normal population. In general, VOR and OKR response parameters changed in a manner consistent with declining function with increasing age. For the VOR this was reflected in declining response amplitudes, although the magnitude of the decline was small relative to the variability of the data. For the OKR the lag time of the response, probably associated with the time required for visual information processing, increased linearly with age at a rate of about 1 ms per year.

  6. Constitutive Modeling and Testing of Polymer Matrix Composites Incorporating Physical Aging at Elevated Temperatures

    NASA Technical Reports Server (NTRS)

    Veazie, David R.

    1998-01-01

    Advanced polymer matrix composites (PMC's) are desirable for structural materials in diverse applications such as aircraft, civil infrastructure and biomedical implants because of their improved strength-to-weight and stiffness-to-weight ratios. For example, the next generation military and commercial aircraft requires applications for high strength, low weight structural components subjected to elevated temperatures. A possible disadvantage of polymer-based composites is that the physical and mechanical properties of the matrix often change significantly over time due to the exposure of elevated temperatures and environmental factors. For design, long term exposure (i.e. aging) of PMC's must be accounted for through constitutive models in order to accurately assess the effects of aging on performance, crack initiation and remaining life. One particular aspect of this aging process, physical aging, is considered in this research.

  7. Racial disparities in age at time of homicide victimization: a test of the multiple disadvantage model.

    PubMed

    Lo, Celia C; Howell, Rebecca J; Cheng, Tyrone C

    2015-01-01

    This study sought the factors associated with race/ethnicity disparities in the age at which homicide deaths tend to occur. We used the multiple disadvantage model to take race into account as we evaluated associations between age at time of homicide victimization and several social structural, mental health-related, and lifestyle factors. Data were derived from the 1993 National Mortality Followback Survey, a cross-sectional interview study of spouses, next of kin, other relatives, and close friends of individuals 15 years and older who died in the United States in 1993. Our results showed age at time of homicide mortality to be related to the three types of factors; race moderated some of these relationships. In general, being employed, married, and a homeowner appeared associated with reduced victimization while young. The relationship of victimization age and employment was not uniform across racial groups, nor was the relationship of victimization age and marital status uniform across groups. Among Blacks, using mental health services was associated with longer life. Homicide by firearm proved important for our Black and Hispanic subsamples, while among Whites, alcohol's involvement in homicide exerted significant effects. Our results suggest that programs and policies serving the various racial/ethnic groups can alleviate multiple disadvantages relevant in homicide victimization at an early age. PMID:24811288

  8. Relation of thromboelastography parameters to conventional coagulation tests used to evaluate the hypercoagulable state of aged fracture patients.

    PubMed

    Liu, Chen; Guan, Zhao; Xu, Qinzhu; Zhao, Lei; Song, Ying; Wang, Hui

    2016-06-01

    Fractures are common among aged people, and rapid assessment of the coagulation status is important. The thromboelastography (TEG) test can give a series of coagulation parameters and has been widely used in clinics. In this research, we looked at fracture patients over 60 and compared their TEG results with those of healthy controls. Since there is a paucity of studies comparing TEG assessments with conventional coagulation tests, we aim to clarify the relationship between TEG values and the values given by conventional coagulation tests.Forty fracture patients (27 femur and 13 humerus) over 60 years old were included in the study. The change in their coagulation status was evaluated by TEG before surgery within 4 hours after the fracture. Changes in TEG parameters were analyzed compared with controls. Conventional coagulation test results for the patients, including activated partial thromboplastin time (APTT), international normalized ratio (INR), fibrinogen, and platelets, were also acquired, and correlation analysis was done with TEG parameters, measuring similar aspects of the coagulation cascade. In addition, the sensitivity and specificity of TEG parameters for detecting raised fibrinogen levels were also analyzed.The K (time to 20 mm clot amplitude) and R (reaction time) values of aged fracture patients were lower than controls. The values for angle, maximal amplitude (MA), and coagulation index (CI) were raised compared with controls, indicating a hypercoagulable state. Correlation analysis showed that there were significant positive correlations between fibrinogen and MA/angle, between platelets and MA, and between APTT and R as well. There was significant negative correlation between fibrinogen and K. In addition, K values have better sensitivity and specificity for detecting elevated fibrinogen concentration than angle and MA values.Aged fracture patients tend to be in a hypercoagulable state, and this could be effectively reflected by a TEG test

  9. Teach Reading, Not Testing: Best Practice in an Age of Accountability

    ERIC Educational Resources Information Center

    Hollingworth, Liz; Drake, Hilleary M.

    2011-01-01

    "Teach Reading, Not Testing" reinforces what teachers already know--test preparation worksheets and drill-and-kill activities do not make children into lifelong readers. The authors' conscientious approach to reading instruction combines an insider perspective on the development of high-stakes tests with classroom experience in achieving…

  10. Evolution of crystal imperfections during current-stress ageing tests of green InGaN light-emitting diodes

    NASA Astrophysics Data System (ADS)

    Lin, Yue; Peng, Zhangbao; Zhu, Lihong; Yan, Wei; Shih, Tien-mo; Wu, Tingzhu; Lu, Yijun; Gao, Yulin; Chen, Zhong; Guo, Ziquan; Liu, Zhuguang

    2016-09-01

    We perform ageing tests under high current on several green InGaN light-emitting diodes and compare the luminous homogeneities of chip surfaces, shapes of external quantum efficiency (EQE) curves, and electroluminescence spectra during different ageing stages. By curve fittings to the EQE curves, with the ABC and two-level models, we discover that a high injection current density can modify the defect configuration in quantum wells even at room temperature, as high-temperature annealing can. For In-rich devices, the removal of localization centers is another origin of luminous intensity decay in addition to the formation of point defects.

  11. Computerized Neuropsychological Assessment in Aging: Testing Efficacy and Clinical Ecology of Different Interfaces

    PubMed Central

    Della Rosa, Pasquale Anthony; Catricalà, Eleonora; Castiglioni, Isabella

    2014-01-01

    Digital technologies have opened new opportunities for psychological testing, allowing new computerized testing tools to be developed and/or paper and pencil testing tools to be translated to new computerized devices. The question that rises is whether these implementations may introduce some technology-specific effects to be considered in neuropsychological evaluations. Two core aspects have been investigated in this work: the efficacy of tests and the clinical ecology of their administration (the ability to measure real-world test performance), specifically (1) the testing efficacy of a computerized test when response to stimuli is measured using a touch-screen compared to a conventional mouse-control response device; (2) the testing efficacy of a computerized test with respect to different input modalities (visual versus verbal); and (3) the ecology of two computerized assessment modalities (touch-screen and mouse-control), including preference measurements of participants. Our results suggest that (1) touch-screen devices are suitable for administering experimental tasks requiring precise timings for detection, (2) intrinsic nature of neuropsychological tests should always be respected in terms of stimuli presentation when translated to new digitalized environment, and (3) touch-screen devices result in ecological instruments being proposed for the computerized administration of neuropsychological tests with a high level of preference from elderly people. PMID:25147578

  12. Computerized neuropsychological assessment in aging: testing efficacy and clinical ecology of different interfaces.

    PubMed

    Canini, Matteo; Battista, Petronilla; Della Rosa, Pasquale Anthony; Catricalà, Eleonora; Salvatore, Christian; Gilardi, Maria Carla; Castiglioni, Isabella

    2014-01-01

    Digital technologies have opened new opportunities for psychological testing, allowing new computerized testing tools to be developed and/or paper and pencil testing tools to be translated to new computerized devices. The question that rises is whether these implementations may introduce some technology-specific effects to be considered in neuropsychological evaluations. Two core aspects have been investigated in this work: the efficacy of tests and the clinical ecology of their administration (the ability to measure real-world test performance), specifically (1) the testing efficacy of a computerized test when response to stimuli is measured using a touch-screen compared to a conventional mouse-control response device; (2) the testing efficacy of a computerized test with respect to different input modalities (visual versus verbal); and (3) the ecology of two computerized assessment modalities (touch-screen and mouse-control), including preference measurements of participants. Our results suggest that (1) touch-screen devices are suitable for administering experimental tasks requiring precise timings for detection, (2) intrinsic nature of neuropsychological tests should always be respected in terms of stimuli presentation when translated to new digitalized environment, and (3) touch-screen devices result in ecological instruments being proposed for the computerized administration of neuropsychological tests with a high level of preference from elderly people. PMID:25147578

  13. Maternal age, investment, and parent-child conflict: a mediational test of the terminal investment hypothesis.

    PubMed

    Schlomer, Gabriel L; Belsky, Jay

    2012-06-01

    Drawing on the evolutionary terminal investment hypothesis and Trivers' (1974) parent-offspring conflict theory, we advance and evaluate a mediational model specifying why and how maternal age, via mating effort and parental investment, affects mother-child conflict. Data from a longitudinal study of 757 families indicate that (a) older maternal age predicts lower mating effort during the child's first 5 years of life, and (b) thereby, higher maternal investment in middle childhood when the child is around 10 years old. (c) Higher maternal investment, in turn, forecasts less child-perceived mother-child conflict in adolescence (age 15). These results proved robust against theoretically relevant covariates (family resources, parity, maternal education, and maternal personality characteristics) and in the context of an autoregressive model. Study limitations are noted and results are discussed in terms of the unique contributions of an evolutionary perspective to the determinants-of-parenting literature. PMID:22468690

  14. Service-Life Extension of Explosive Escape Devices

    NASA Technical Reports Server (NTRS)

    Bement, L. J.; Schimmel, M. L.

    1987-01-01

    Chemical and functional tests yield conservative service-life estimates. Approach to extension of service lives of explosive devices in aircraft escape system developed, supported by testing of representative candidate devices to evaluate quantitatively effects of service, age, and degradation, and to enable responsible, conservative service-life determinations. Five types of explosive components evaluated: rigid and flexible explosive transfer lines; one-way transfers; flexible, linear-shaped charges; and initiation-handles. Extension of service in realistic manner provides both cost savings and increased system reliability.

  15. Skilled performance tests and their use in diagnosing handedness and footedness at children of lower school age 8–10

    PubMed Central

    Musalek, Martin

    2015-01-01

    Previous research has shown that hand and foot preferences do not develop in parallel in children and it has been discovered that in children foot preference stabilizes later. Therefore, the aim of this study is to verify whether the differences in stabilization will also be manifested through less consistent results of selected skilled foot performance tests in a comparison with selected skilled hand performance tests. A total of 210 8–10 year old children from elementary schools were recruited for this study. Hand and foot preferences were first tested using hand and foot preference observable measure tasks; consequently, all participants performed four skilled hand performance tests and three foot performance tests. Unlike in complex skilled hand performance tests, which showed a significant convergent validity 0.56–0.89 with hand preference tasks, in complex skilled foot performance tests a very low convergent validity 0.25–0.46 with foot preference tasks was detected. The only skilled foot performance indicator which showed an acceptable convergent validity with foot preference tasks was the “foot tapping” test 0.65–0.85, which represents rather a gross motor activity. Moreover, further results of the tests suggest that complex or fine motor performance tests used for diagnosing laterality of the lower limb that have a manipulative character probably do not represent suitable indicators for children in the given age category. The same trend was revealed in both females and males. This indicates that the level of laterality assessed as difference in skilfulness between the preferred and the non-preferred limb in children in the given age group probably develops in the same way in both genders. PMID:25628579

  16. Attitudes Towards Non-Invasive Prenatal Testing for Aneuploidy Among United States Adults of Reproductive Age

    PubMed Central

    Sayres, Lauren C.; Goodspeed, Taylor A.; Cho, Mildred K.

    2014-01-01

    Objective(s) To determine how adults in the United States (US) view non-invasive prenatal testing using cell-free fetal DNA (cffDNA testing) in order to help estimate uptake. Study Design A national sample of 1,861 US-based adults was surveyed using a validated online survey instrument. The survey was administered by a commercial survey research company. Respondents were randomized to receive a survey about prenatal testing for trisomy 13 and 18 or trisomy 21. Participants were asked to select among testing modalities, including cffDNA testing, and rank the features of testing that they considered most important to decision making. Results There was substantive interest in the use of cffDNA testing rather than traditional screening mechanisms with a minority of respondents reporting that they would support the use of both methods in combination. The lower rates of false negative and false positive test results and the ability to use the test earlier in the pregnancy were the most highly rated benefits of cffDNA testing. Participants expressed strong support for diagnostic confirmation via invasive testing after a positive result from either screening or cffDNA testing. However, almost one-third of participants reported that they would not endorse the use of either invasive or non-invasive prenatal testing. Conclusion(s) There appears to be support for uptake of non-invasive prenatal tests. Clinical guidelines should therefor go forward in providing guidance on how to integrate non-invasive methods into current standard of care. However, our findings indicate that even when accuracy, which is rated by patients as the most important aspect of prenatal testing, is significantly improved over existing screening methods and testing is offered non-invasively, the number of individuals who reported that they would decline any testing remained the same. Attention should therefor be directed at ensuring that the right of informed refusal of prenatal testing is not impacted

  17. Relationship between the single-breath N test and age, sex, and smoking habit in three North American cities.

    PubMed

    Buist, A S; Ghezzo, H; Anthonisen, N R; Cherniack, R M; Ducic, S; Macklem, P T; Manfreda, J; Martin, R R; McCarthy, D; Ross, B B

    1979-08-01

    This report describes a collaborative study conducted in Montreal, Canada, Portland, Ore., and Winnipeg, Canada, to establish the relationship between the single-breath N2 test and age, sex, and smoking and to determine the prevalence of functional abnormalities in these populations. In nonsmokers, age-related regressions for closing volume, closing capacity, and the slope of phase III obtained from the single-breath N2 test, plus the ratio of the I-s forced expiratory volume to the forced vital capacity had very similar slopes, suggesting that differences in geographic location, climate, air pollution, and occupation had no effect on lung function detectable by these tests. Among the 6 city/six groups there was no systematic difference in the prevalence of functional abnormalities between the cities, but closing capacity expressed as a percentage of total lung capacity was abnormal most often in men and the slope of the alveolar plateau was abnormal most often in women. The prevalence of respiratory symptoms within different smoking categories was similar in the 3 cities. Although the number of cigarettes smoked had a significant effect on every test except the ratio of the I-s forced expiratory volume to forced vital capacity in men, the effect of age was considerably greater than the effect of smoking, and the dose-response relationship was weak. We conclude that additional factors may interact with smoking to place a smoker at risk of developing chronic airflow limitation. PMID:475152

  18. Are We There Yet? Exploring the Impact of Translating Cognitive Tests for Dementia Using Mobile Technology in an Aging Population

    PubMed Central

    Ruggeri, Kai; Maguire, Áine; Andrews, Jack L.; Martin, Eric; Menon, Shantanu

    2016-01-01

    This study examines implications of the expanded use of mobile platforms in testing cognitive function, and generates evidence on the impact utilizing mobile platforms for dementia screen. The Saint Louis University Mental State examination (SLUMS) was ported onto a computerized mobile application named the Cambridge University Pen to Digital Equivalence assessment (CUPDE). CUPDE was piloted and compared to the traditional pen and paper version, with a common comparator test for both groups. Sixty healthy participants (aged 50–79) completed both measurements. Differences were tested between overall outcomes, individual items, and relationship with the comparator. Significant differences in the overall scores between the two testing versions as well as within individual items were observed. Even when groups were matched by cognitive function and age, scores on SLUMS original version (M = 19.75, SD = 3) were significantly higher than those on CUPDE (M = 15.88, SD = 3.5), t(15) = 3.02, p < 0.01. Mobile platforms require the development of new normative standards, even when items can be directly translated. Furthermore, these must fit aging populations with significant variance in familiarity with mobile technology. Greater understanding of the interplay and related mechanisms between auditory and visual systems, which are not well understood yet in the context of mobile technologies, is mandatory. PMID:27014053

  19. Are We There Yet? Exploring the Impact of Translating Cognitive Tests for Dementia Using Mobile Technology in an Aging Population.

    PubMed

    Ruggeri, Kai; Maguire, Áine; Andrews, Jack L; Martin, Eric; Menon, Shantanu

    2016-01-01

    This study examines implications of the expanded use of mobile platforms in testing cognitive function, and generates evidence on the impact utilizing mobile platforms for dementia screen. The Saint Louis University Mental State examination (SLUMS) was ported onto a computerized mobile application named the Cambridge University Pen to Digital Equivalence assessment (CUPDE). CUPDE was piloted and compared to the traditional pen and paper version, with a common comparator test for both groups. Sixty healthy participants (aged 50-79) completed both measurements. Differences were tested between overall outcomes, individual items, and relationship with the comparator. Significant differences in the overall scores between the two testing versions as well as within individual items were observed. Even when groups were matched by cognitive function and age, scores on SLUMS original version (M = 19.75, SD = 3) were significantly higher than those on CUPDE (M = 15.88, SD = 3.5), t (15) = 3.02, p < 0.01. Mobile platforms require the development of new normative standards, even when items can be directly translated. Furthermore, these must fit aging populations with significant variance in familiarity with mobile technology. Greater understanding of the interplay and related mechanisms between auditory and visual systems, which are not well understood yet in the context of mobile technologies, is mandatory. PMID:27014053

  20. 75 FR 59723 - Proposed Collection; Comment Request; Testing Successful Health Communications Surrounding Aging...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-28

    ... a generic clearance for a range of research data collection procedures to ensure that they... research on aging to the scientific community, health care providers, and the public.'' The primary... Public liaison will collect this information through formative qualitative research with its...

  1. Maternal Age at Childbirth and Offspring Disruptive Behaviors: Testing the Causal Hypothesis

    ERIC Educational Resources Information Center

    D'Onofrio, Brian M.; Goodnight, Jackson A.; Van Hulle, Carol A.; Rodgers, Joseph Lee; Rathouz, Paul J.; Waldman, Irwin D.; Lahey, Benjamin B.

    2009-01-01

    Background: Recent studies suggest that the association between maternal age at childbearing (MAC) and children's disruptive behaviors is the result of family factors that are confounded with both variables, rather than a casual effect of environmental factors specifically related to MAC. These studies, however, relied on restricted samples and…

  2. Aging Reduces Veridical Remembering but Increases False Remembering: Neuropsychological Test Correlates of Remember-Know Judgments

    ERIC Educational Resources Information Center

    McCabe, David P.; Roediger, Henry L., III; McDaniel, Mark A.; Balota, David A.

    2009-01-01

    In 1985 Tulving introduced the remember-know procedure, whereby subjects are asked to distinguish between memories that involve retrieval of contextual details (remembering) and memories that do not (knowing). Several studies have been reported showing age-related declines in remember hits, which has typically been interpreted as supporting…

  3. Bootstrap-Bayesian OSL approach for poorly-bleached sediment sequences tested with dendrochronological age constraints

    NASA Astrophysics Data System (ADS)

    Wallinga, J.; Den Ouden, J.; Cunningham, A. C.; Copini, P.; Versendaal, A. J.; Sass-Klaassen, U. G. W.; Bos, G.; Beerens, A. M. A. J.; Riksen, M. J. P. M.

    2012-04-01

    Optically stimulated luminescence (OSL) dating is widely accepted as a cornerstone dating method for sediments. The method is particularly suitable for aeolian sediments formed between 10 and 100 ka, but is also widely applied to non-ideal deposits. Where light exposure prior to burial is insufficient for complete resetting of the OSL signal in all grains, additional processing is needed to determine accurate burial ages. The Minimum Age Model (MAM; Galbraith et al., 1999) has proven to be very powerful for such analysis, but results on sequences of poorly-bleached samples indicate that MAM uncertainty estimates are too optimistic. We have recently proposed a method to improve MAM uncertainty estimates (Cunningham & Wallinga, 2012). This method involves repeated calculation of the MAM result, with slightly changing input data and model parameters. Resulting uncertainty ranges are wider and more realistic than those of the standard MAM. Moreover, the approach allows construction of probability density distributions of age which can be used for Bayesian modelling (e.g. Oxcal) to combine data of different samples and/or data obtained using other methods. Here we explore the possibilities of the bootstrapped MAM approach combined with Bayesian analysis by detailed investigation of a 2-m thick sequence of aeolian deposits formed during the past 150 years. Processed OSL results on ten samples taken in a vertical sequence compare favourably with dendrochronological age constraints on stem discs taken from buried sections of the tree.

  4. Sn-Ag-Cu to Cu joint current aging test and evolution of resistance and microstructure

    NASA Astrophysics Data System (ADS)

    Xu, Di Erick; Chow, Jasper; Mayer, Michael; Jung, Jae Pil; Yoon, Jong Hyun

    2015-11-01

    SAC 305 solder bump with 800 μm diameter were produced and soldered to a custom substrate with Cu lines as leads that allow for resistance measurement during current aging. The measured joint resistance values (leads plus solder bump) before aging are 7.7 ± 1.8 mΩ and 11.8 ± 2.8 mΩ at room temperature and 160°C, respectively. In general, the resistance of the solder joint increases instantly by about 1 mΩ, when subjected to a 2.2 A aging current at 160°C. The increase is gradual in the following hours of aging and more drastic as it approaches the final failure. Four stages are identified in the resistance signal curve and compared with observations from cross sections. The stages are IMC growth, crack formation and propagation, intermittent crack healing-forming, and final failure resulting in an open connection at the cathode. Recently a periodical drop and rise behavior was reported for the resistance signal. This behavior is reproduced and attributed to the intermittent crack healing-forming stage. The healing events observed are faster than the sampling time. Possibly, as current is concentrated when bypassing interfacial cracks, local melting occurs partially filling cracks before resolidifying. [Figure not available: see fulltext.

  5. Subacute toxicity testing with young birds: Response in relation to age and intertest variability of LC50 estimates

    USGS Publications Warehouse

    Hill, E.F.; Camardese, M.B.

    1982-01-01

    The variability in toxic response of Japanese quail (Coturnix coturnix japonica) to a standardized 5-day subacute feeding trial was studied while age was increased at weekly intervals from 1 to 21 days and at different times with 14-day-old birds. The objectives were to identify the strengths and limitations of this subacute toxicity protocol and to provide possible explanations for differences in response among the various classes of pesticides. The variables included the median lethal concentration (LC50), the dose-response slope, food consumption, mortality patterns, and procedures of preparing toxic diets. Carbamate, organophosphate, chlorinated hydrocarbon, and organic mercury compounds were represented. A total of 60 subacute tests were involved in this evaluation. The general conclusions of the study are as follows: (1) The basic protocol yields good within-laboratory reproducibility of results. (2) The LC50s increase as birds grow older, and the change was reasonably predictable between 7 and 21 days of age. (3) Monitoring of time-related response patterns, such as food consumption, onset and remission of overt toxicity, and mortality, is critical to the evaluation of potential hazard. (4) Different orders of toxicity may occur at different ages for an array of compounds, but differences do not appear to be large enough to seriously alter the interpretation. (5) For optimal comparisons, all testing should be conducted on birds of a single age.

  6. Mapping the clockworks: what does the Clock Drawing Test assess in normal and pathological aging?

    PubMed

    Paula, Jonas Jardim de; Miranda, Débora Marques de; Moraes, Edgar Nunes de; Malloy-Diniz, Leandro Fernandes

    2013-10-01

    The Clock Drawing Test (CDT) is a cognitive screening tool used in clinical and research settings. Despite its role on the assessment of global cognitive functioning, the specific cognitive components required for test performance are still unclear. We aim to assess the role of executive functioning, global cognitive status, visuospatial abilities, and semantic knowledge on Shulman's CDT performance. Fifty-three mild cognitive impairment, 60 Alzheimer's dementia, and 57 normal elderly controls performed the CDT, the Frontal Assessment Battery, the Mini-Mental State Examination, the Stick Design Test, and a naming test (TN-LIN). An ordinal regression assessed specific neuropsychological influences on CDT performance. All the cognitive variables were related to the CDT, accounting for 53% of variance. The strongest association was between the CDT and executive functions, followed by global cognitive status, visuospatial processing, and semantic knowledge. Our result confirms the multidimensional nature of the test and the major role of executive functions on performance. PMID:24212511

  7. Aging influences on working memory for hand movements: a test of the metamemory deficit hypothesis.

    PubMed

    Miyahara, Motohide

    2007-01-01

    This study examined the role verbal labels play in working memory for hand movements between young and older adults. All young adults formed verbal labels spontaneously to remember hand movements, whereas only 20% of the older adults did so. After instructed to use verbal labels, the older adults performed at a level close to the level of the young adults. These results indicated an age-related decline of the ability to spontaneously recruit a verbal labeling strategy that can be learned and retained. However, there was no significant interaction between age group and instruction, suggesting the need for further investigation into factors other than verbal labels, including the capacity of the visuospatial memory, interference from earlier items, and fatigue. PMID:17886016

  8. Combining magnetic sorting of mother cells and fluctuation tests to analyze genome instability during mitotic cell aging in Saccharomyces cerevisiae.

    PubMed

    Patterson, Melissa N; Maxwell, Patrick H

    2014-01-01

    Saccharomyces cerevisiae has been an excellent model system for examining mechanisms and consequences of genome instability. Information gained from this yeast model is relevant to many organisms, including humans, since DNA repair and DNA damage response factors are well conserved across diverse species. However, S. cerevisiae has not yet been used to fully address whether the rate of accumulating mutations changes with increasing replicative (mitotic) age due to technical constraints. For instance, measurements of yeast replicative lifespan through micromanipulation involve very small populations of cells, which prohibit detection of rare mutations. Genetic methods to enrich for mother cells in populations by inducing death of daughter cells have been developed, but population sizes are still limited by the frequency with which random mutations that compromise the selection systems occur. The current protocol takes advantage of magnetic sorting of surface-labeled yeast mother cells to obtain large enough populations of aging mother cells to quantify rare mutations through phenotypic selections. Mutation rates, measured through fluctuation tests, and mutation frequencies are first established for young cells and used to predict the frequency of mutations in mother cells of various replicative ages. Mutation frequencies are then determined for sorted mother cells, and the age of the mother cells is determined using flow cytometry by staining with a fluorescent reagent that detects bud scars formed on their cell surfaces during cell division. Comparison of predicted mutation frequencies based on the number of cell divisions to the frequencies experimentally observed for mother cells of a given replicative age can then identify whether there are age-related changes in the rate of accumulating mutations. Variations of this basic protocol provide the means to investigate the influence of alterations in specific gene functions or specific environmental conditions on

  9. Relationships among the Y balance test, Berg Balance Scale, and lower limb strength in middle-aged and older females

    PubMed Central

    Lee, Dong-Kyu; Kang, Min-Hyeok; Lee, Tae-Sik; Oh, Jae-Seop

    2015-01-01

    Background: Older females have less dynamic postural control and muscle strength than do middle-aged females. Aging-related strength losses may limit balancing performance. Objective: The purpose of this study was to investigate the ability of the Y Balance Test (YBT) and lower limb strength to discriminate between females in 2 age groups, the relationship between YBT distance and the Berg Balance Scale (BBS), and the degree to which performance on YBT distance is related to lower limb strength in middle-aged and older females. Method: The 40 healthy, independently active females were divided into 2 groups: older and middle-aged. The participants underwent measurements of YBT distance using the YBT, maximal muscular strength of the lower limbs using a handheld dynamometer, and the BBS. Results: The YBT distance in 3 directions and lower limb muscle strength for both lower limbs were significantly lower in the older adults than in the middle-aged group. A moderate correlation but insignificant correlation was found between the YBT composite distance and the BBS score. In the older females, YBT distance was significantly positively correlated with strength of the knee flexor and hip abductor. In the middle-aged group, YBT distance was significantly positively correlated with strength of the knee flexor and hip extensor. Conclusions: Performance on the YBT was influenced by the strength of lower limb. We suggested that YBT can be used to alternative as a measurement of dynamic balance. Proper training programs for older people could include not only strengthening exercises but also YBT performance to improve balance. PMID:26039033

  10. Experiences of Women Who Underwent Predictive BRCA 1/2 Mutation Testing Before the Age of 30.

    PubMed

    Brunstrom, Kate; Murray, Alexandra; McAllister, Marion

    2016-02-01

    This qualitative interview study focuses on the experiences of a sample of British female BRCA 1/2 carriers who had predictive testing before the age of 30, which is the minimum age for breast screening in the UK. Following appropriate informed consent procedures participants were recruited through the Cancer Genetics Service for Wales. Semi-structured interviews were conducted face-to-face with seven participants, transcribed in full and analyzed using thematic analysis. The motives for testing and perceived advantages described by participants were similar to those identified in previous studies with older participants, such as increased awareness and knowledge and feeling more in control. However some of the perceived disadvantages were specific to younger women, including feeling pressured to make important life decisions earlier than they would have liked, such as about family planning and risk reducing surgery. Participants also reported feeling abandoned or forgotten because of lack of ongoing clinical contact, or feeling "stuck waiting" for screening to begin. However, none felt that these disadvantages were a reason to regret having testing. Findings in this small study suggest that having BRCA 1/2 predictive testing can have positive outcomes for young women even though they may be unable to access interventions such as breast screening. However it may be helpful to encourage young women during pre-test counseling to explore the decisions and choices they may face. These young women could benefit from ongoing support and follow up and increased interaction with healthcare professionals. PMID:25983051

  11. Full scale evaluation of diffuser ageing with clean water oxygen transfer tests.

    PubMed

    Krampe, J

    2011-01-01

    Aeration is a crucial part of the biological wastewater treatment in activated sludge systems and the main energy user of WWTPs. Approximately 50 to 60% of the total energy consumption of a WWTP can be attributed to the aeration system. The performance of the aeration system, and in the case of fine bubble diffused aeration the diffuser performance, has a significant impact on the overall plant efficiency. This paper seeks to isolate the changes of the diffuser performance over time by eliminating all other influencing parameters like sludge retention time, surfactants and reactor layout. To achieve this, different diffusers have been installed and tested in parallel treatment trains in two WWTPs. The diffusers have been performance tested in clean water tests under new conditions and after one year of operation. A set of material property tests describing the diffuser membrane quality was also performed. The results showed a significant drop in the performance of the EPDM diffuser in the first year which resulted in similar oxygen transfer efficiency around 16 g/m3/m for all tested systems. Even though the tested silicone diffusers did not show a drop in performance they had a low efficiency in the initial tests. The material properties indicate that the EPDM performance loss is partly due to the washout of additives. PMID:22097050

  12. Downstream Testing and Subsequent Procedures After Coronary Computed Tomographic Angiography Following Coronary Stenting in Patients ≥65 Years of Age

    PubMed Central

    Mudrick, Daniel; Kaltenbach, Lisa A.; Shah, Bimal; Lytle, Barbara; Masoudi, Frederick A.; Mark, Daniel B.; Federspiel, Jerome J.; Cowper, Patricia A.; Green, Cynthia; Douglas, Pamela S.

    2013-01-01

    Limited data are available on the use of coronary computed tomography angiography (CCTA) in patients who have received percutaneous coronary intervention (PCI). To evaluate patterns of cardiac testing including CCTA after PCI, we created a retrospective observational data set linking the National Cardiovascular Data Registry® CathPCI Registry® baseline data with longitudinal inpatient and outpatient Medicare claims data for patients who received coronary stenting between November 1, 2005 and December 31, 2007. Among 192,009 PCI patients (median age 74 years), the first test after coronary stenting was CCTA for 553 (0.3%), stress testing for 89,900 (46.8%), and coronary angiography for 22,308 (11.6%); 79,248 (41.3%) had no further testing. Patients referred to CCTA first had generally similar or lower baseline risk than those referred for stress testing or catheterization first. Compared to patients with stress testing first after PCI, patients who underwent CCTA first had higher unadjusted rates of subsequent noninvasive testing (10% vs. 3%), catheterization (26% vs. 15%), and revascularization (13% vs. 8%) within 90 days of initial post-PCI testing (p<0.0001 for all). In conclusion, despite similar or lesser risk profiles, patients initially evaluated with CCTA after PCI had more downstream testing and revascularization than patients initially evaluated with stress testing. It is unclear whether these differences derive from patient selection, the performance of CCTA relative to other testing strategies, or the association of early CCTA adoption with distinct patterns of care. PMID:22651883

  13. Self-Testing of Vision in Age-Related Macula Degeneration: A Longitudinal Pilot Study Using a Smartphone-Based Rarebit Test.

    PubMed

    Winther, Christina; Frisén, Lars

    2015-01-01

    Purpose. There is a need for efficient self-tests of vision in patients with neovascular age-related macula degeneration. A new tablet/smartphone application aiming to meet this need is described and its performance is assessed in a longitudinal pilot study. Materials and Methods. The new MultiBit Test (MBT) employs segmented digits defined by rarebits, that is, receptive field-size bright dots briefly presented against a dark background. The number of rarebits per digit segment was varied in a cyclic fashion, in preset steps. There were no fixation demands. Twenty-eight patients with neovascular AMD of varying severity were monitored for an average of 30 weeks. Test scores were evaluated on an individual basis, by contrasting observed trends with the clinical status recorded at independently scheduled clinical examinations. Results. Serial plots of MBT results revealed gradual improvement after successful antineovascular treatment. Recurrences were signalled by gradual deteriorations of results. Test results remained stable during clinically stable time intervals. MBT results agreed well with clinical assessments whereas an acuity test performed at chance level. The MBT was well accepted by all subjects. Conclusions. The MBT appears to have a good potential for effective self-testing of vision in AMD and merits large-scale studies. Exploration of MBT performance with other forms of macula conditions may be worthwhile. PMID:26124958

  14. Self-Testing of Vision in Age-Related Macula Degeneration: A Longitudinal Pilot Study Using a Smartphone-Based Rarebit Test

    PubMed Central

    2015-01-01

    Purpose. There is a need for efficient self-tests of vision in patients with neovascular age-related macula degeneration. A new tablet/smartphone application aiming to meet this need is described and its performance is assessed in a longitudinal pilot study. Materials and Methods. The new MultiBit Test (MBT) employs segmented digits defined by rarebits, that is, receptive field-size bright dots briefly presented against a dark background. The number of rarebits per digit segment was varied in a cyclic fashion, in preset steps. There were no fixation demands. Twenty-eight patients with neovascular AMD of varying severity were monitored for an average of 30 weeks. Test scores were evaluated on an individual basis, by contrasting observed trends with the clinical status recorded at independently scheduled clinical examinations. Results. Serial plots of MBT results revealed gradual improvement after successful antineovascular treatment. Recurrences were signalled by gradual deteriorations of results. Test results remained stable during clinically stable time intervals. MBT results agreed well with clinical assessments whereas an acuity test performed at chance level. The MBT was well accepted by all subjects. Conclusions. The MBT appears to have a good potential for effective self-testing of vision in AMD and merits large-scale studies. Exploration of MBT performance with other forms of macula conditions may be worthwhile. PMID:26124958

  15. Sex- and age-related mortality profiles during famine: testing the 'body fat' hypothesis.

    PubMed

    Speakman, John R

    2013-11-01

    During famines females generally have a mortality advantage relative to males, and the highest levels of mortality occur in the very young and the elderly. One popular hypothesis is that the sex differential in mortality may reflect the greater body fatness combined with lower metabolism of females, which may also underpin the age-related patterns of mortality among adults. This study evaluated the 'body fat' hypothesis using a previously published and validated mathematical model of survival during total starvation. The model shows that at a given body weight females would indeed be expected to survive considerably longer than males in the absence of food. At a mass of 70 kg for example a female aged 30 would survive for 144 days compared with life expectancy of only 95 days for a male of the same age and weight. This effect is contributed to by both the higher body fatness and lower metabolism of the females at a given body weight. However, females are generally smaller than males and in addition to a sex effect there was also a major effect of body size - heavier individuals survive longer. When this body size effect was removed by considering survival in relation to BMI the sex effect was much reduced, and could be offset by a relatively small difference in pre-famine BMI between the sexes. Nevertheless, combining these predictions with observed mean BMIs of males and females across 48 countries at the low end of the obesity spectrum suggests that in the complete absence of food females would survive on average about 40% longer (range 6 to 64.5%) than males. The energy balance model also predicted that older adult individuals should survive much longer than younger adult individuals, by virtue of their lower resting metabolic rates and lower activity levels. Observations of the female survival advantage in multiple famines span a much wider range than the model prediction (5% to 210%). This suggests in some famines body fatness may be a significant factor

  16. Age and education adjusted normative data and discriminative validity for Rey's Auditory Verbal Learning Test in the elderly Greek population.

    PubMed

    Messinis, Lambros; Nasios, Grigorios; Mougias, Antonios; Politis, Antonis; Zampakis, Petros; Tsiamaki, Eirini; Malefaki, Sonia; Gourzis, Phillipos; Papathanasopoulos, Panagiotis

    2016-01-01

    Rey's Auditory Verbal Learning Test (RAVLT) is a widely used neuropsychological test to assess episodic memory. In the present study we sought to establish normative and discriminative validity data for the RAVLT in the elderly population using previously adapted learning lists for the Greek adult population. We administered the test to 258 cognitively healthy elderly participants, aged 60-89 years, and two patient groups (192 with amnestic mild cognitive impairment, aMCI, and 65 with Alzheimer's disease, AD). From the statistical analyses, we found that age and education contributed significantly to most trials of the RAVLT, whereas the influence of gender was not significant. Younger elderly participants with higher education outperformed the older elderly with lower education levels. Moreover, both clinical groups performed significantly worse on most RAVLT trials and composite measures than matched cognitively healthy controls. Furthermore, the AD group performed more poorly than the aMCI group on most RAVLT variables. Receiver operating characteristic (ROC) analysis was used to examine the utility of the RAVLT trials to discriminate cognitively healthy controls from aMCI and AD patients. Area under the curve (AUC), an index of effect size, showed that most of the RAVLT measures (individual and composite) included in this study adequately differentiated between the performance of healthy elders and aMCI/AD patients. We also provide cutoff scores in discriminating cognitively healthy controls from aMCI and AD patients, based on the sensitivity and specificity of the prescribed scores. Moreover, we present age- and education-specific normative data for individual and composite scores for the Greek adapted RAVLT in elderly subjects aged between 60 and 89 years for use in clinical and research settings. PMID:26588427

  17. Population normative data for the CERAD Word List and Victoria Stroop Test in younger- and middle-aged adults: Cross-sectional analyses from the Framingham Heart Study

    PubMed Central

    Hankee, Lisa D.; Preis, Sarah R.; Piers, Ryan J.; Beiser, Alexa S.; Devine, Sherral A.; Liu, Yulin; Seshadri, Sudha; Wolf, Philip A.; Au, Rhoda

    2016-01-01

    Objective To provide baseline normative data on tests of verbal memory and executive function for non-demented young to middle age adults. Methods The Consortium to Establish a Registry for Alzheimer’s Disease Word List task (CERAD-WL) and Victoria Stroop Test (VST) were administered to 3362 Framingham Heart Study (FHS) volunteer participants aged 24-78 years. Analyses of the effects of age, sex and education were conducted. Normative data on traditional measures and error responses are reported for each test. Results Traditional measures were significantly associated with both age and education in this younger-aged cohort. Error responses also evidenced significant age and education effects. Conclusion These data provide a normative comparison for assessment of verbal memory and executive functioning capabilities in young adults and may be utilized as a tool for preclinical studies of disease in younger aged adults. PMID:27410241

  18. Effects of Timing, Sex, and Age on Site-Specific Gastrointestinal Permeability Testing in Children and Adults

    PubMed Central

    McOmber, Mark E.; Ou, Ching-Nan; Shulman, Robert J.

    2010-01-01

    Summary Objectives Measurement of gastrointestinal (GI) permeability is used commonly in research and often clinically. Despite its utility, little is known about sugar excretion timeframes or the potential effects of age and gender in GI permeability testing. We sought to determine the timeframes of sugar excretion and the potential effects of age and gender on urinary recovery of the sugars. Methods Healthy adults (n=17) and children (n=15) fasted four hours after the evening meal and then ingested a solution of sucrose, lactulose, mannitol, and sucralose. Urine was collected at 30, 60, and 90 minutes after ingestion and then each time the subjects voided over the next 24 hr. Each urine void was collected separately. Results Median age for the adults was 47.5 yr. (range 21-57 yr.) and for children 10 yr. (5-17). There were no differences between children and adults in mean percent dose of sugar recovered. The time of peak urinary recovery of the sugars was generally similar between children and adults. Sucrose urinary recovery declined with age (P = 0.008; r2 = 0.19) unrelated to gender. Lactulose and sucralose urinary recovery declined with age in females (P = 0.05, r2 = 0.24 and P = 0.011, r2 = 0.41, respectively) but not in males. Conclusions Overall, sugar urinary recovery is comparable in children and adults. Specific sugar urinary recovery may change as a function of age and/or gender. These results need to be taken into account when planning and interpreting GI permeability studies. PMID:20081547

  19. Moving beyond the pros and cons of automating cognitive testing in pathological aging and dementia: the case for equal opportunity.

    PubMed

    Wesnes, Keith A

    2014-01-01

    The lack of progress over the last decade in developing treatments for Alzheimer's disease has called into question the quality of the cognitive assessments used while also shifting the emphasis from treatment to prophylaxis by studying the disorder at earlier stages, even prior to the development of cognitive symptoms. This has led various groups to seek cognitive tests which are more sensitive than those currently used and which can be meaningfully administered to individuals with mild or even no cognitive impairment. Although computerized tests have long been used in this field, they have made little inroads compared with non-automated tests. This review attempts to put in perspective the relative utilities of automated and non-automated tests of cognitive function in therapeutic trials of pathological aging and the dementias. Also by a review of the automation of cognitive tests over the last 150 years, it is hoped that the notion that such procedures are novel compared with pencil-and-paper testing will be dispelled. Furthermore, data will be presented to illustrate that older individuals and patients with dementia are neither stressed nor disadvantaged when tested with appropriately developed computerized methods. An important aspect of automated testing is that it can assess all aspects of task performance, including the speed of cognitive processes, and data are presented on the advantages this can confer in clinical trials. The ultimate objectives of the review are to encourage decision making in the field to move away from the automated/non-automated dichotomy and to develop criteria pertinent to each trial against which all available procedures are evaluated. If we are to make serious progress in this area, we must use the best tools available, and the evidence suggests that automated testing has earned the right to be judged against the same criteria as non-automated tests. PMID:25478021

  20. Moving beyond the pros and cons of automating cognitive testing in pathological aging and dementia: the case for equal opportunity

    PubMed Central

    2014-01-01

    The lack of progress over the last decade in developing treatments for Alzheimer’s disease has called into question the quality of the cognitive assessments used while also shifting the emphasis from treatment to prophylaxis by studying the disorder at earlier stages, even prior to the development of cognitive symptoms. This has led various groups to seek cognitive tests which are more sensitive than those currently used and which can be meaningfully administered to individuals with mild or even no cognitive impairment. Although computerized tests have long been used in this field, they have made little inroads compared with non-automated tests. This review attempts to put in perspective the relative utilities of automated and non-automated tests of cognitive function in therapeutic trials of pathological aging and the dementias. Also by a review of the automation of cognitive tests over the last 150 years, it is hoped that the notion that such procedures are novel compared with pencil-and-paper testing will be dispelled. Furthermore, data will be presented to illustrate that older individuals and patients with dementia are neither stressed nor disadvantaged when tested with appropriately developed computerized methods. An important aspect of automated testing is that it can assess all aspects of task performance, including the speed of cognitive processes, and data are presented on the advantages this can confer in clinical trials. The ultimate objectives of the review are to encourage decision making in the field to move away from the automated/non-automated dichotomy and to develop criteria pertinent to each trial against which all available procedures are evaluated. If we are to make serious progress in this area, we must use the best tools available, and the evidence suggests that automated testing has earned the right to be judged against the same criteria as non-automated tests. PMID:25478021

  1. Capacity of the Catalan and Spanish Versions of the Bilingual Aphasia Test to Distinguish between Healthy Aging, Mild Cognitive Impairment and Alzheimer's Disease

    ERIC Educational Resources Information Center

    Gomez-Ruiz, Isabel; Aguilar-Alonso, Angel

    2011-01-01

    This study analysed the capacity of the Catalan and Spanish versions of the Bilingual Aphasia Test (BAT) to distinguish between normal and pathological aging. Both versions of the test were administered to 45 bilingual subjects: 15 healthy aging subjects, 15 patients with mild cognitive impairment and 15 patients with Alzheimer's disease. To…

  2. Executive Functioning in Normal Aging: A Study of Action Planning Using the Zoo Map Test

    ERIC Educational Resources Information Center

    Allain, P.; Nicoleau, S.; Pinon, K.; Etcharry-Bouyx, F.; Barre, J.; Berrut, G.; Dubas, F.; Gall, D.L.

    2005-01-01

    A particularly important aspect of executive functioning involves the ability to form and carry out complex plans, that is to say planning. This study aimed to investigate planning in 18 older and 16 younger normal participants using an ecological planning subtask derived from the Behavioural Assessment of the Dysexecutive Syndrome test battery,…

  3. Mental Rotation Performance in Primary School Age Children: Are There Gender Differences in Chronometric Tests?

    ERIC Educational Resources Information Center

    Jansen, P.; Schmelter, A.; Quaiser-Pohl, C.; Neuburger, S.; Heil, M.

    2013-01-01

    In contrast to the well documented male advantage in psychometric mental rotation tests, gender differences in chronometric experimental designs are still under dispute. Therefore, a systematic investigation of gender differences in mental rotation performance in primary-school children is presented in this paper. A chronometric mental rotation…

  4. Test Score Gaps between Private and Government Sector Students at School Entry Age in India

    ERIC Educational Resources Information Center

    Singh, Abhijeet

    2014-01-01

    Various studies have noted that students enrolled in private schools in India perform better on average than students in government schools. In this paper, I show that large gaps in the test scores of children in private and public sector education are evident even at the point of initial enrollment in formal schooling and are associated with…

  5. Auditory and Visual Continuous Performance Tests: Relationships with Age, Gender, Cognitive Functioning, and Classroom Behavior

    ERIC Educational Resources Information Center

    Lehman, Elyse Brauch; Olson, Vanessa A.; Aquilino, Sally A.; Hall, Laura C.

    2006-01-01

    Elementary school children in three grade groups (Grades K/1, 3, and 5/6) completed either the auditory or the visual 1/9 vigilance task from the Gordon Diagnostic System (GDS) as well as subtests from the Wechsler Intelligence Scale for Children--Third Edition and auditory or visual processing subtests from the Woodcock-Johnson Tests of Cognitive…

  6. Age-Related Performance on the Brixton Spatial Anticipation Test in Healthy Child and Adolescent Girls: A Preliminary Evaluation.

    PubMed

    Harvey, Lucy; Rose, Mark; Jonsson, Rosie; Lask, Bryan

    2016-01-01

    The Brixton Spatial Anticipation Test assesses individuals' cognitive flexibility in terms of rule detection and attainment. It has been used to assess executive functioning in both clinical and nonclinical adult samples. However, little is currently known about the suitability of this task for younger populations. The current study therefore aimed to provide an initial exploration of this task's suitability for young people. Brixton responses from a healthy sample of children and adolescents were presented to investigate performance in both rule detection and rule attainment, respectively. A convenience sample of 72 female participants (Mage = 14.95 years, SD = 1.53 years, range = 11-17 years; MIQ = 103.76, SD = 10.81) was studied. The sample was divided according to age into four groups (11-12 years, 13-14 years, 15 years, and 16-17 years) to allow for developmental trajectory. No significant age performance differences were found. Small effect sizes between age groups lend support to the null findings. The current study suggests that the Brixton task norms are suitable for use with individuals aged 11 to 17 years old. However, normative work is still needed in this area, incorporating an adult sample for comparison, to comment upon the developmental trajectory specific to this task. PMID:25928610

  7. Sex differences in cognitive ageing: testing predictions derived from life-history theory in a dioecious nematode.

    PubMed

    Zwoinska, Martyna K; Kolm, Niclas; Maklakov, Alexei A

    2013-12-01

    Life-history theory maintains that organisms allocate limited resources to different traits to maximize fitness. Learning ability and memory are costly and known to trade-off with longevity in invertebrates. However, since the relationship between longevity and fitness often differs between the sexes, it is likely that sexes will differentially resolve the trade-off between learning and longevity. We used an established associative learning paradigm in the dioecious nematode Caenorhabditis remanei, which is sexually dimorphic for lifespan, to study age-related learning ability in males and females. In particular, we tested the hypothesis that females (the shorter-lived sex) show higher learning ability than males early in life but senesce faster. Indeed, young females outperformed young males in learning a novel association between an odour (butanone) and food (bacteria). However, while learning ability and offspring production declined rapidly with age in females, males maintained high levels of these traits until mid-age. These results not only demonstrate sexual dimorphism in age-related learning ability but also suggest that it conforms to predictions derived from the life-history theory. PMID:24120565

  8. Petrography, age, and paleomagnetism of basaltic lava flows in coreholes at Test Area North (TAN), Idaho National Engineering Laboratory

    SciTech Connect

    Lanphere, M.A.; Champion, D.E.; Kuntz, M.A.

    1994-12-31

    The petrography, age, and paleomagnetism were determined on basalt from 21 lava flows comprising about 1,700 feet of core from two coreholes (TAN CH No. 1 and TAN CH No. 2) in the Test Area North (TAN) area of the Idaho National Engineering Laboratory (INEL). Paleomagnetic studies were made on two additional cores from shallow coreholes in the TAN area. K-Ar ages and paleomagnetism also were determined on nearby surface outcrops of Circular Butte. Paleomagnetic measurements were made on 416 samples from four coreholes and on a single site in surface lava flows of Circular Butte. K-Ar ages were measured on 9 basalt samples from TAN CH No. 1 and TAN CH No. 2 and one sample from Circular Butte. K-Ar ages ranged from 1.044 Ma to 2.56 Ma. All of the samples have reversed magnetic polarity and were erupted during the Matuyama Reversed Polarity Epoch. The purpose of investigations was to develop a three-dimensional stratigraphic framework for geologic and hydrologic studies including potential volcanic hazards to facilities at the INEL and movement of radionuclides in the Snake River Plain aquifer.

  9. [Change in conflict strength measured by Color-Word Test in childhood, adulthood, and the aged].

    PubMed

    Hama, H; Hashimoto, E

    1985-08-01

    A life span survey of conflict induced in color naming when words and colors appear in incongruent combination was carried out. Subjects' ages ranged from six years to 89 years, totaling 721. As the index of conflict, (C-B)/A was used. The result indicated that conflict scores were highest in six-year-old children and the next highest in the eldery of 70 to 89 years. The result of ANOVA indicated no sex difference on conflict scores, but showed a difference in faster performance by females on the color and color-word cards. The result suggested that six-year olds are immature in cognitive ability and that the 70-year olds and above declined in their cognitive ability. The elevation of conflict scores in 10 years may be due to the stage of puberty. PMID:4068397

  10. Glycosylated Hemoglobin Testing in the National Social Life, Health, and Aging Project

    PubMed Central

    O’Doherty, Katie; Schumm, L. Philip; McClintock, Martha K.; Huang, Elbert S.

    2014-01-01

    Objectives. Longitudinal biomeasures of health are still new in nationally representative social science survey research. Data measuring blood sugar control provide opportunities for understanding the development of diabetes and its complications in older adults, but researchers must be aware that some of the differences across time can be due to variations in measurement procedures. This is a well-recognized issue whenever all samples cannot be assayed at the same time and we sought to present the analytic methods to quantify and adjust for the variation. Method. We collected and analyzed HbA1C, glycated hemoglobin, a biomeasure of average blood sugar concentrations within the past few months. Improvements were made in the collection protocol for Wave 2, and assays were performed by a different lab. Results. The HbA1C data obtained during Wave 1 and Wave 2 are consistent with the expected population distributions for differences by gender, age, race/ethnicity, and diabetes status. Age-adjusted mean HbA1C declined slightly from Wave 1 to Wave 2 by −0.19 (95% confidence interval [CI]: −0.27, −0.10), and the average longitudinal change was −0.12 (95% CI: −0.18, −0.06). Discussion. Collection of HbA1C in Wave 2 permits researchers to examine the relationship between HbA1C and new health and social measures added in Wave 2, and to identify factors related to the change in HbA1C. Changes in collection protocol and labs between waves may have yielded small systematic differences that require analysts to carefully interpret absolute HbA1C values. We recommend analytic methods for cross wave differences in HbA1C and steps to ensure cross wave comparability in future studies PMID:25360021

  11. Enhanced muscle activity during lumbar extension exercise with pelvic stabilization

    PubMed Central

    Lee, Ho-Seong

    2015-01-01

    The purpose of this study was to investigate whether pelvic stabilization affects multifidus (MF) and iliocostalis lumborum (IL) muscle activities during dynamic extension exercise. Nine males (age, 25.1±6.3 yr; height, 176.6±2.4 cm; body mass, 74.9±6.7 kg) performed an isometric lumbar extension strength test and dynamic exercise in an upright seated position with or without pelvic stabilization. The electromyography and muscle strength of the MF and IL muscles were measured when the subjects performed the isometric lumbar extension strength test at the trunk angle 110°, 146°, and 182°. In addition, the trunk extensor muscle activities were measured using 50% muscle strength of maximum isometric strength during a dynamic trunk extension exercise. The MF and IL muscle activities were significantly higher at 110°, 146°, and 182° with pelvic stabilization than that without pelvic stabilization during the isometric lumbar extension strength test (P<0.05) and the dynamic exercise (P<0.05). These results suggest that the lumbar extension exercise with pelvic stabilization may be more effective for MF and IL muscle activity compared to that without pelvic stabilization. PMID:26730390

  12. AGE AND REPEATED BIOPSY INFLUENCE ANTEMORTEM PRP(CWD) TESTING IN MULE DEER (ODOCOILEUS HEMIONUS) IN COLORADO, USA.

    PubMed

    Geremia, Chris; Hoeting, Jennifer A; Wolfe, Lisa L; Galloway, Nathan L; Antolin, Michael F; Spraker, Terry R; Miller, Michael W; Hobbs, N Thompson

    2015-10-01

    Biopsy of rectal mucosa-associated lymphoid tissue provides a useful, but imperfect, live-animal test for chronic wasting disease (CWD) in mule deer (Odocoileus hemionus). It is difficult and expensive to complete these tests on free-ranging animals, and wildlife health managers will benefit from methods that can accommodate test results of varying quality. To this end, we developed a hierarchical Bayesian model to estimate the probability that an individual is infected based on test results. Our model was estimated with the use of data on 210 adult female mule deer repeatedly tested during 2010-14. The ability to identify infected individuals correctly declined with age and may have been influenced by repeated biopsy. Fewer isolated lymphoid follicles (where PrP(CWD) accumulates) were obtained in biopsies of older deer and the proportion of follicles showing PrP(CWD) was reduced. A deer's genotype in the prion gene (PRNP) also influenced detection. At least five follicles were needed in a biopsy to assure a 95% accurate test in PRNP genotype 225SS deer. PMID:26251986

  13. Comparative Emissions Testing of Vehicles Aged on E0, E15 and E20 Fuels

    SciTech Connect

    Vertin, K.; Glinsky, G.; Reek, A.

    2012-08-01

    The Energy Independence and Security Act passed into law in December 2007 has mandated the use of 36 billion ethanol equivalent gallons per year of renewable fuel by 2022. A primary pathway to achieve this national goal is to increase the amount of ethanol blended into gasoline. This study is part of a multi-laboratory test program coordinated by DOE to evaluate the effect of higher ethanol blends on vehicle exhaust emissions over the lifetime of the vehicle.

  14. Influence of Li Addition to Zn-Al Alloys on Cu Substrate During Spreading Test and After Aging Treatment

    NASA Astrophysics Data System (ADS)

    Gancarz, Tomasz; Pstrus, Janusz; Cempura, Grzegorz; Berent, Katarzyna

    2016-08-01

    The spreading of Zn-Al eutectic-based alloys with 0.05 wt.%, 0.1 wt.%, and 0.2 wt.% Li on Cu substrate has been studied using the sessile drop method in presence of QJ201 flux. Wetting tests were performed after 1 min, 3 min, 8 min, 15 min, 30 min, and 60 min of contact at temperatures of 475°C, 500°C, 525°C, and 550°C. Samples after spreading at 500°C for 1 min were subjected to aging for 1 day, 10 days, and 30 days at temperature of 120°C, 170°C, and 250°C. The spreadability of eutectic Zn-5.3Al alloy with different Li contents on Cu substrate was determined in accordance with ISO 9455-10:2013-03. Selected solidified solder-substrate couples were, after spreading and aging tests, cross-sectioned and subjected to scanning electron microscopy, energy-dispersive spectroscopy (EDS), and x-ray diffraction (XRD) analysis of the interfacial microstructure. An experiment was designed to demonstrate the effect of Li addition on the kinetics of the formation and growth of CuZn, Cu5Zn8, and CuZn4 intermetallic compound (IMC) phases, during spreading and aging. The IMC layers formed at the interface were identified using XRD and EDS analyses. Increasing addition of Li to Zn-Al alloy caused a reduction in the thickness of the IMC layer at the interface during spreading, and an increase during aging. The activation energy was calculated, being found to increase for the Cu5Zn8 phase but decrease for the CuZn and CuZn4 phases with increasing Li content in the Zn-Al-Li alloys. The highest value of 142 kJ mol-1 was obtained for Zn-Al with 1.0 Li during spreading and 69.2 kJ mol-1 for Zn-Al with 0.05 Li during aging. Aging at 250°C caused an increase in only the Cu5Zn8 layer, which has the lowest Gibbs energy in the Cu-Zn system. This result is connected to the high diffusion of Cu from the substrate to the solder.

  15. Do I turn left or right? Effects of sex, age, experience and exit route on maze test performance in sheep.

    PubMed

    Hunter, Damien S; Hazel, Susan J; Kind, Karen L; Liu, Hong; Marini, Danila; Owens, Julie A; Pitcher, Julia B; Gatford, Kathryn L

    2015-02-01

    Brain development and function are susceptible to perturbation by environmental factors. Sheep are increasingly being used as a neurodevelopmental model due to timing similarities with humans, but effects of age, experience and sex on cognition are not well characterised in this species. We therefore studied memory and reversal learning in sheep using a modified Y-maze at two ages: naive 18 weeks old (18N: 23 male, 17 female), experienced 40 week old sheep that had previously been tested at 18 weeks (40E: 22 male, 17 female), and naive 40 weeks old (40N: 4 male, 10 female). Younger naive animals (18N) required more trials and time to solve the first reversal task (task R1) than 40E (P=0.007 and P<0.001 respectively). Experience also improved outcomes, with 40N sheep requiring more time to solve tasks L (P=0.034) and R1 (P=0.002) than 40E. Increasing age (40N cf. 18N) decreased bleat frequency in tasks R1, M2 and R2 (each P<0.05). In 40N females, outcomes also differed by exit method in task R1, with those that exited via an indirect route taking less time to pass tasks R1 (P=0.009) and R2 (P=0.015) than those that used a direct route. Age plus experience improved learning outcomes, demonstrating knowledge retention for 22 weeks in this species, whilst age alone affected mostly behavioral responses. These results provide comparison data, and can be utilised to improve experimental design, for studies of neurodevelopment in the sheep. PMID:25449405

  16. Pulmonary function test in healthy school children of 8 to 14 years age in south Gujarat region, India

    PubMed Central

    Doctor, Tahera H.; Trivedi, Sangeeta S.; Chudasama, Rajesh K.

    2010-01-01

    Objective: To obtain reference values for FEV1, FVC, FEV1% and PEFR among children aged 8-14 years in south Gujarat region of India. Materials and Methods: This cross-sectional study was conducted among 655 normal healthy school children (408 boys and 247 girls) of Surat city aged 8 to 14 years studying in V to VII standard during November 2007 to April 2008. Height, weight, body surface area were measured. All included children were tested in a sitting position with the head straight after taking written consent from parents. Spirometry was done using the spirometer “Spirolab II” MIR 010. Spirometer used in the study facilitates the total valuation of lung function including forced vital capacity (FVC), forced expiratory volume in one second (FEV1), forced expiratory volume ratio in one second (FEV1%) and peak expiratory flow rate (PEFR). Results: FVC, FEV1 and PEFR were found to be statistically significant in the study groups. For FVC and FEV1, highest correlation was found with age in girls and height in boys. For FEV1%, significant negative correlation was found with age and height in both sexes, but positive correlation was found with surface area. Similarly, PEFR showed highest correlation with surface area in boys and girls. Conclusion: Variables such as FVC, FEV1 and PEFR show good positive correlation with height, age and body surface area in both sexes. There is a need to have regional values for the prediction of normal spirometric parameters in a country like India with considerable diversity. PMID:20931033

  17. LIMB demonstration project extension

    SciTech Connect

    Not Available

    1990-09-21

    The purpose of the DOE limestone injection multistage burner (LIMB) Demonstration Project Extension is to extend the data base on LIMB technology and to expand DOE's list of Clean Coal Technologies by demonstrating the Coolside process as part of the project. The main objectives of this project are: to demonstrate the general applicability of LIMB technology by testing 3 coals and 4 sorbents (total of 12 coal/sorbent combinations) at the Ohio Edison Edgewater plant; and to demonstrate that Coolside is a viable technology for improving precipitator performance and reducing sulfur dioxide emissions while acceptable operability is maintained. Progress is reported. 3 figs.

  18. Portable Extensible Viewer

    NASA Technical Reports Server (NTRS)

    Horowitz, Jay G.

    1997-01-01

    The use of Nonuniform Rational B-Splines (NURBS) to represent geometry and data offers a standard way to facilitate the multidisciplinary analysis and design of aeropropulsion products. Using standard geometry defined by NURBS throughout design, analysis, part definition, manufacture, and test processes saves money and time. The Portable Extensible Viewer (PEV) offers engineers of different disciplines a means to view and manipulate NURBS geometry and associated data. Under the guidance of a team of Lewis, Boeing Company, and Navy personnel, PEV was developed by NASA Lewis Research Center's Computer Services Division for Lewis' Interdisciplinary Technology Office. The aeropropulsion industry provided input to the design requirements.

  19. Damage Assessment of Creep Tested and Thermally Aged Udimet 520 Using Acousto-Ultrasonics

    NASA Technical Reports Server (NTRS)

    Gyekenyesi, Andrew L.; Kautz, Harold E.; Cao, Wei

    2001-01-01

    Due to elevated temperatures and excessive stresses, turbine components may experience creep behavior. As a result, it is desirable to monitor and assess the current condition of such components. This study employed the Acousto-Ultrasonics (AU) method in an effort to monitor the state of the material at various percentages of used up creep life in the nickel base alloy, Udimet 520. A stepped specimen (i.e., varying cross sectional area) was employed which allowed for a postmortem nondestructive evaluation (NDE) analysis of the various levels of used up life. The overall objectives here were two fold: First, a user friendly, graphical interface AU system was developed, and second the new AU system was applied as an NDE tool to assess distributed damage resulting from creep. The experimental results demonstrated that the AU method shows promise as an NDE tool capable of detecting material changes as a function of used up creep life. Furthermore, the changes in the AU parameters were mainly attributed to the case of combined load and elevated temperature (i.e., creep) and not simply because of a timed exposure at elevated temperature (i.e., heat treatment or thermal aging).

  20. Determining brittle extension and shear strain using fault length and displacement systematics: Part II: Data evaluation and test of the theory

    NASA Astrophysics Data System (ADS)

    Twiss, Robert J.; Marrett, Randall

    2010-12-01

    We use the theoretical relations developed in Part I of this work to evaluate the self-consistency of fault-length and fault-displacement data gathered in domains of one and two dimensions from the Yucca Mountain area and from the coalfields in south Yorkshire, U.K. These data sets are not all self-consistent. For the Yucca Mt. area, the theory shows that, the volume over which the sampling of the faults must occur should have a horizontal width no smaller than 2.4 times the horizontal length of the largest fault, and a depth no smaller than 1.6 times the vertical extent of the largest vertical-equivalent-fault. It also shows that the volumetric extension must be ≥95% of the extension of a two-dimensional domain and ≥80% of the extension of a one-dimensional domain. The theory successfully accounts for the observed cumulative extensional strain derived from fault-displacement data from a one-dimensional sampling domain at Yucca Mt., Nevada, U.S.A. Faults up to about four orders of magnitude smaller than the largest fault make a significant contribution to the strain. The most robust calculation of cumulative fractional strain requires the parameters inferred from sampling displacement in a one-dimensional domain. This sampling procedure therefore provides the most reliable results.

  1. A New Extension of the Binomial Error Model for Responses to Items of Varying Difficulty in Educational Testing and Attitude Surveys

    PubMed Central

    Wiley, James A.; Martin, John Levi; Herschkorn, Stephen J.; Bond, Jason

    2015-01-01

    We put forward a new item response model which is an extension of the binomial error model first introduced by Keats and Lord. Like the binomial error model, the basic latent variable can be interpreted as a probability of responding in a certain way to an arbitrarily specified item. For a set of dichotomous items, this model gives predictions that are similar to other single parameter IRT models (such as the Rasch model) but has certain advantages in more complex cases. The first is that in specifying a flexible two-parameter Beta distribution for the latent variable, it is easy to formulate models for randomized experiments in which there is no reason to believe that either the latent variable or its distribution vary over randomly composed experimental groups. Second, the elementary response function is such that extensions to more complex cases (e.g., polychotomous responses, unfolding scales) are straightforward. Third, the probability metric of the latent trait allows tractable extensions to cover a wide variety of stochastic response processes. PMID:26544974

  2. Correlation of Chemical and Physical Test Data for the Environmental Ageing of Tefzel (ETFE). Revised

    NASA Technical Reports Server (NTRS)

    Morgan, G. J.; Campion, R. P.

    1997-01-01

    In a similar approach to that used for the previously issued correlation report for Coflon (CAPP/M.10), this report aims to identify any correlations between mechanical property changes and chemical/morphological changes for Tefzel, using information supplied in other MERL and TRI project reports. Differences identified with Coflon behaviour will be of scientific interest as well as appropriate to project applications, as Tefzel and Coflon are chemical isomers. Owing to the considerable chemical resistance of Tefzel, much of its testing so far has been based on mechanical properties. Where changes have occurred, chemical analysis can now be targeted more effectively. Relevant test data collated here include: tensile modulus and related properties, permeation coefficients, % crystallinity, some crack growth resistance measurements, and other observations where significant. Fluids based on methanol and amine (Fluid G), a mixture of methane, carbon dioxide and hydrogen sulphide gases plus an aqueous amine solution (Fluid F), and an aromatic oil mix of heptane, cyclohexane, toluene and 1-propanol (Fluid I) have affected Tefzel to varying degrees, and are discussed in some detail herein.

  3. Correlation of Chemical and Physical Test Data for the Environmental Ageing of Tefzel (ETFE)

    NASA Technical Reports Server (NTRS)

    Morgan, G. J.; Campion, R. P.

    1996-01-01

    In a similar approach to that used for the previously issued correlation report for Coflon (CAPP/M.10), this report aims to identify any correlations between mechanical property changes and chemical/morphological changes for Tefzel, using information supplied in other MERL and TRI project reports (plus latest data which will be included in final reports for Phase 1). Differences identified with Coflon behaviour will be of scientific interest as well as appropriate to project applications, as Tefzel and Coflon are chemical isomers. Owing to the considerable chemical resistance of Tefzel, much of its testing so far has been based on mechanical properties. Where changes have occurred, chemical analysis can now be targeted more effectively. Relevant test data collated here include: tensile modulus and related properties, permeation coefficients, % crystallinity, and other observations where significant. Fluids based on methanol and amine (Fluid G), a mixture of methane, carbon dioxide and hydrogen sulphide gases plus an aqueous amine solution (Fluid F), and an aromatic oil mix of heptane, cyclohexane, toluene and I-propanol (Fluid 1) have affected Tefzel to varying degrees, and are discussed in some detail herein.

  4. Ability to learn inhaler technique in relation to cognitive scores and tests of praxis in old age

    PubMed Central

    Allen, S; Ragab, S

    2002-01-01

    Clinical observations have shown that some older patients are unable to learn to use a metered dose inhaler (MDI) despite having a normal abbreviated mental test (AMT) score, possibly because of dyspraxia or unrecognised cognitive impairment. Thirty inhaler-naive inpatients (age 76–94) with an AMT score of 8–10 (normal) were studied. Standard MDI training was given and the level of competence reached was scored (inhalation score). A separate observer performed the minimental test (MMT), Barthel index, geriatric depression score (GDS), ideational dyspraxia test (IDT), and ideomotor dyspraxia test (IMD). No correlative or threshold relationship was found between inhalation score and Barthel index, GDS, or IDT. However, a significant correlation was found between inhalation score and IMD (r = 0.45, p = 0.039) and MMT (r = 0.48, p = 0.032) and threshold effects emerged in that no subject with a MMT score of less than 23/30 had an inhalation score of 5/10 or more (adequate technique requires 6/10 or more), and all 17/18 with an inhalation score of 6/10 or more had an IMD of 14/20 or more. The three patients with a MMT >22 and inhalation score <6 had abnormal IMD scores. Inability to learn an adequate inhaler technique in subjects with a normal AMT score appears to be due to unrecognised cognitive impairment or dyspraxia. The MMT is probably a more useful screening test than the AMT score in this context. PMID:11796871

  5. Extent of the last ice sheet in northern Scotland tested with cosmogenic 10Be exposure ages

    USGS Publications Warehouse

    Phillips, W.M.; Hall, A.M.; Ballantyne, C.K.; Binnie, S.; Kubik, P.W.; Freeman, S.

    2008-01-01

    The extent of the last British-Irish Ice Sheet (BIIS) in northern Scotland is disputed. A restricted ice sheet model holds that at the global Last Glacial Maximum (LGM; ca. 23-19 ka) the BIIS terminated on land in northern Scotland, leaving Buchan, Caithness and the Orkney Islands ice-free. An alternative model implies that these three areas were ice-covered at the LGM, with the BIIS extending offshore onto the adjacent shelves. We test the two models using cosmogenic 10Be surface exposure dating of erratic boulders and glacially eroded bedrock from the three areas. Our results indicate that the last BIIS covered all of northern Scotland during the LGM, but that widespread deglaciation of Caithness and Orkney occurred prior to rapid warming at ca. 14.5 ka. Copyright ?? 2008 John Wiley & Sons, Ltd.

  6. Utility of the Test of Memory Malingering (TOMM) in Children Ages 4–7 Years with and without ADHD

    PubMed Central

    Schneider, Heather; Kirk, John Woodard; Mahone, E. Mark

    2014-01-01

    There is growing consensus that assessment for non-credible performance is a necessary component of pediatric neuropsychological examination. The current study examined the utility and validity of the Test of Memory Malingering (TOMM) in children ages 4–7 years with and without Attention-deficit/Hyperactivity Disorder (ADHD). Sixty-six children (30 controls, 36 ADHD) completed all three TOMM trials. There were no significant group differences in total score on any trial, or passing rate for Trial 2 or Retention. Four-year-olds with ADHD achieved “passing” score on Trial 1 less often than controls. Across groups, performance on Trial 2 and Retention improved with age, such that 85% of the sample achieved passing score. Four-year olds had greater difficulty and achieved passing score significantly less often than children 5–7 years. Moreover, half of the 4-year olds performed worse on Retention than Trial 2, calling into question the utility of the Retention trial at this age. Performance was associated with IQ only within the ADHD group on the Retention trial. Results suggest that the TOMM can be used with confidence in clinical groups as young as 5 years. Among 4-year olds, performance appears dependent on severity of ADHD or disruptive behaviors, and may be associated with factors other than effort. PMID:25247460

  7. Sensitization phenomena on aged SAF 2205 duplex stainless steel and their control using the electrochemical potentiokinetic reactivation test

    SciTech Connect

    Angelini, E.; Benedetti, B. de; Maizza, G.; Rosalbino, F. . Dept. of Materials Science and Chemical Engineering)

    1999-06-01

    Microstructural changes and resulting properties were studied for SAF 2205 (UNS S31803) austeno-ferritic stainless steel (SS) aged between 700 C and 900 C for up to 2 weeks and then water-quenched. Quantitative metallography coupled with x-ray diffraction techniques were adopted to follow ferrite ([alpha]) transformation with subsequent formation of secondary austenite ([gamma][sub 2]) and sigma ([sigma]) phase. The kinetic model of a transformation was interpreted in the form of an Avrami-type expression. The electrochemical potentiokinetic reactivation (EPR) test was used to evaluate the degree of sensitization of the aged specimens. Results were compared with results from the corrosion test in boiling nitric acid (HNO[sub 3]). Influences of the transformation of ferrite into austenite, sigma phase, and of other microstructural variations such as chromium nitride (Cr[sub 2]N) precipitation on stability of the passive film were shown. The susceptibility to intergranular corrosion phenomena was caused by chromium depletion caused by sigma phase precipitation, while chromium nitrides appeared less harmful. Results were expressed as an isocharge line diagram that allowed concise identification of sensitization and desensitization ranges.

  8. The gap in the color-magnitude diagram of NGC 2420: A test of convective overshoot and cluster age

    NASA Technical Reports Server (NTRS)

    Demarque, Pierre; Sarajedini, Ata; Guo, X.-J.

    1994-01-01

    Theoretical isochrones have been constructed using the OPAL opacities specifically to study the color-magnitude diagram of the open star cluster NGC 2420. This cluster provides a rare test of core convection in intermediate-mass stars. At the same time, its age is of interest because of its low metallicity and relatively high Galactic latitude for an open cluster. The excellent color-magnitude diagram constructed by Anthony-Twarog et al. (1990) allows a detailed fit of the isochrones to the photometric data. We discuss the importance of convective overshoot at the convective core edge in determining the morphology of the gap located near the main-sequence turnoff. We find that given the assumptions made in the models, a modest amount of overshoot (0.23 H(sub p)) is required for the best fit. Good agreement is achieved with all features of the turnoff gap for a cluster age of 2.4 +/- 0.2 Gyr. We note that a photometrically complete luminosity function near the main-sequence turnoff and subgiant branch would also provide an important test of the overshoot models.

  9. Testing Persistence of Cohort Effects in the Epidemiology of Suicide: an Age-Period-Cohort Hysteresis Model

    PubMed Central

    Chauvel, Louis; Leist, Anja K.; Ponomarenko, Valentina

    2016-01-01

    Birth cohort effects in suicide rates are well established, but to date there is no methodological approach or framework to test the temporal stability of these effects. We use the APC-Detrended (APCD) model to robustly estimate intensity of cohort effects identifying non-linear trends (or ‘detrended’ fluctuations) in suicide rates. The new APC-Hysteresis (APCH) model tests temporal stability of cohort effects. Analysing suicide rates in 25 WHO countries (periods 1970–74 to 2005–09; ages 20–24 to 70–79) with the APCD method, we find that country-specific birth cohort membership plays an important role in suicide rates. Among 25 countries, we detect 12 nations that show deep contrasts among cohort-specific suicide rates including Italy, Australia and the United States. The APCH method shows that cohort fluctuations are not stable across the life course but decline in Spain, France and Australia, whereas they remain stable in Italy, the United Kingdom and the Netherlands. We discuss the Spanish case with elevated suicide mortality of cohorts born 1965–1975 which declines with age, and the opposite case of the United States, where the identified cohort effects of those born around 1960 increase smoothly, but statistically significant across the life course. PMID:27442027

  10. CR TKA UHMWPE wear tested after artificial aging of the vitamin E treated gliding component by simulating daily patient activities.

    PubMed

    Schwiesau, Jens; Fritz, Bernhard; Kutzner, Ines; Bergmann, Georg; Grupp, Thomas M

    2014-01-01

    The wear behaviour of total knee arthroplasty (TKA) is dominated by two wear mechanisms: the abrasive wear and the delamination of the gliding components, where the second is strongly linked to aging processes and stress concentration in the material. The addition of vitamin E to the bulk material is a potential way to reduce the aging processes. This study evaluates the wear behaviour and delamination susceptibility of the gliding components of a vitamin E blended, ultra-high molecular weight polyethylene (UHMWPE) cruciate retaining (CR) total knee arthroplasty. Daily activities such as level walking, ascending and descending stairs, bending of the knee, and sitting and rising from a chair were simulated with a data set received from an instrumented knee prosthesis. After 5 million test cycles no structural failure of the gliding components was observed. The wear rate was with 5.62 ± 0.53 mg/million cycles falling within the limit of previous reports for established wear test methods. PMID:25506594

  11. CR TKA UHMWPE Wear Tested after Artificial Aging of the Vitamin E Treated Gliding Component by Simulating Daily Patient Activities

    PubMed Central

    Schwiesau, Jens; Fritz, Bernhard; Kutzner, Ines; Bergmann, Georg; Grupp, Thomas M.

    2014-01-01

    The wear behaviour of total knee arthroplasty (TKA) is dominated by two wear mechanisms: the abrasive wear and the delamination of the gliding components, where the second is strongly linked to aging processes and stress concentration in the material. The addition of vitamin E to the bulk material is a potential way to reduce the aging processes. This study evaluates the wear behaviour and delamination susceptibility of the gliding components of a vitamin E blended, ultra-high molecular weight polyethylene (UHMWPE) cruciate retaining (CR) total knee arthroplasty. Daily activities such as level walking, ascending and descending stairs, bending of the knee, and sitting and rising from a chair were simulated with a data set received from an instrumented knee prosthesis. After 5 million test cycles no structural failure of the gliding components was observed. The wear rate was with 5.62 ± 0.53 mg/million cycles falling within the limit of previous reports for established wear test methods. PMID:25506594

  12. Testing Persistence of Cohort Effects in the Epidemiology of Suicide: an Age-Period-Cohort Hysteresis Model.

    PubMed

    Chauvel, Louis; Leist, Anja K; Ponomarenko, Valentina

    2016-01-01

    Birth cohort effects in suicide rates are well established, but to date there is no methodological approach or framework to test the temporal stability of these effects. We use the APC-Detrended (APCD) model to robustly estimate intensity of cohort effects identifying non-linear trends (or 'detrended' fluctuations) in suicide rates. The new APC-Hysteresis (APCH) model tests temporal stability of cohort effects. Analysing suicide rates in 25 WHO countries (periods 1970-74 to 2005-09; ages 20-24 to 70-79) with the APCD method, we find that country-specific birth cohort membership plays an important role in suicide rates. Among 25 countries, we detect 12 nations that show deep contrasts among cohort-specific suicide rates including Italy, Australia and the United States. The APCH method shows that cohort fluctuations are not stable across the life course but decline in Spain, France and Australia, whereas they remain stable in Italy, the United Kingdom and the Netherlands. We discuss the Spanish case with elevated suicide mortality of cohorts born 1965-1975 which declines with age, and the opposite case of the United States, where the identified cohort effects of those born around 1960 increase smoothly, but statistically significant across the life course. PMID:27442027

  13. Classification of selected cardiopulmonary variables of elite athletes of different age, gender, and disciplines during incremental exercise testing.

    PubMed

    Zinner, Christoph; Sperlich, Billy; Wahl, Patrick; Mester, Joachim

    2015-01-01

    Incremental exercise testing is frequently used as a tool for evaluating determinants of endurance performance. The available reference values for the peak oxygen uptake (VO2peak), % of VO2peak, running speed at the lactate threshold (vLT), running economy (RE), and maximal running speed (vpeak) for different age, gender, and disciplines are not sufficient for the elite athletic population. The key variables of 491 young athletes (age range 12-21 years; 250 males, 241 females) assessed during a running step test protocol (2.4 m s(-1); increase 0.4 m s(-1) 5 min(-1)) were analysed in five subgroups, which were related to combat-, team-, endurance-, sprint- and power-, and racquet-related disciplines. Compared with female athletes, male athletes achieved a higher vpeak (P = 0.004). The body mass, lean body mass, height, abs. VO2peak (ml min(-1)), rel. VO2peak (ml kg(-1) min(-1)), rel. VO2peak (ml min(-1) kg(-0.75)), and RE were higher in the male participants compared with the females (P < 0.01). The % of VO2 at vLT was lower in the males compared with the females (P < 0.01). No differences between gender were detected for the vLT (P = 0.17) and % of VO2 at vLT (P = 0.42). This study is one of the first to provide a broad spectrum of data to classify nearly 500 elite athletes aged 12-21 years of both gender and different disciplines. PMID:26413450

  14. Contribution of sympathetic activation to coronary vasodilatation during the cold pressor test in healthy men: effect of ageing

    PubMed Central

    Monahan, Kevin D; Feehan, Robert P; Sinoway, Lawrence I; Gao, Zhaohui

    2013-01-01

    The sympathetic nervous system is an important regulator of coronary blood flow. The cold pressor test (CPT) is a powerful sympathoexcitatory stressor. We tested the hypotheses that: (1) CPT-induced sympathetic activation elicits coronary vasodilatation in young adults that is impaired with advancing age and (2) combined α- and β-adrenergic blockade diminishes/abolishes these age-related differences. Vascular responses of the left anterior descending artery to the CPT were determined by transthoracic Doppler echocardiography before (pre-blockade) and during (post-blockade) systemic co-administration of α- and β-adrenergic antagonists in young (n= 9; 26 ± 1 years old, mean ± SEM) and older healthy men (n= 9; 66 ± 2 years old). Coronary vascular resistance (CVR; mean arterial pressure/coronary blood velocity) was used as an index of vascular tone. CPT decreased CVR (i.e. coronary vasodilatation occurred) in young (Δ–33 ± 6%), but not older men (Δ–3 ± 4%; P < 0.05 vs. young) pre-blockade. Adrenergic blockade abolished CPT-induced coronary vasodilatation in young men (Δ–33 ± 6%vs. Δ 0 ± 6%, pre-blockade vs. post-blockade, respectively; P < 0.05) such that responses post-blockade mirrored those of older men (Δ–3 ± 4%vs. Δ 8 ± 9%; both P > 0.05 compared to young pre-blockade). Impaired CPT-induced coronary vasodilatation could not be explained by a reduced stimulus for vasodilatation as group and condition effects persisted when CVR responses were expressed relative to myocardial oxygen demand (rate–pressure product). These data indicate that the normal coronary vascular response to sympathetic activation in young men is pronounced vasodilatation and this effect is lost with age as the result of an adrenergic mechanism. These findings may help explain how acute sympathoexcitation may precipitate angina and coronary ischaemic events, particularly in older adults. PMID:23478134

  15. Boiler-turbine life extension

    SciTech Connect

    Natzkov, S.; Nikolov, M.

    1995-12-01

    The design life of the main power equipment-boilers and turbines is about 105 working hours. The possibilities for life extension are after normatively regulated control tests. The diagnostics and methodology for Boilers and Turbines Elements Remaining Life Assessment using up to date computer programs, destructive and nondestructive control of metal of key elements of units equipment, metal creep and low cycle fatigue calculations. As well as data for most common damages and some technical decisions for elements life extension are presented.

  16. Validation of the self-reported hearing questions in the Irish Longitudinal Study on Ageing against the Whispered Voice Test

    PubMed Central

    2014-01-01

    Background Self report questions are often used in population studies to assess sensory efficacy and decline. These questions differ in their validity in assessing sensory impairment depending on the wording of the question and the characteristics of the population. We tested the validity of the self-report questions on hearing efficacy (self reported hearing, ability in following a conversation, use of a telephone and use of hearing aids) used in The Irish Longitudinal Study on Ageing (TILDA). Methods We tested sensitivity and specificity, positive and negative predictive values of each question against the Whispered Voice Test, a relatively easy to administer and cost effective alternative to the standard audiometric test. Results In this population the question ‘Is your hearing (with or without a hearing appliance)/ Excellent/Very Good/Good/Fair/Poor?’ showed the best diagnostic value in relation to the other questions (sensitivity 55.56% and specificity 94.67%). The question ‘Can you use a normal telephone?’ was deemed ineffective because of a very poor sensitivity (5.56%) and was proposed for exclusion from subsequent waves of TILDA. Conclusions We showed that this validity check was useful to select the questions that most effectively assess hearing deficits and provided crucial information for the subsequent waves. We argue that longitudinal studies using self-reports of sensory efficacy would benefit from a similar check. PMID:24928453

  17. Derivation of a Provisional, Age-dependent, AIS2+ Thoracic Risk Curve for the THOR50 Test Dummy via Integration of NASS Cases, PMHS Tests, and Simulation Data.

    PubMed

    Laituri, Tony R; Henry, Scott; El-Jawahri, Raed; Muralidharan, Nirmal; Li, Guosong; Nutt, Marvin

    2015-11-01

    A provisional, age-dependent thoracic risk equation (or, "risk curve") was derived to estimate moderate-to-fatal injury potential (AIS2+), pertaining to men with responses gaged by the advanced mid-sized male test dummy (THOR50). The derivation involved two distinct data sources: cases from real-world crashes (e.g., the National Automotive Sampling System, NASS) and cases involving post-mortem human subjects (PMHS). The derivation was therefore more comprehensive, as NASS datasets generally skew towards younger occupants, and PMHS datasets generally skew towards older occupants. However, known deficiencies had to be addressed (e.g., the NASS cases had unknown stimuli, and the PMHS tests required transformation of known stimuli into THOR50 stimuli). For the NASS portion of the analysis, chest-injury outcomes for adult male drivers about the size of the THOR50 were collected from real-world, 11-1 o'clock, full-engagement frontal crashes (NASS, 1995-2012 calendar years, 1985-2012 model-year light passenger vehicles). The screening for THOR50-sized men involved application of a set of newly-derived "correction" equations for self-reported height and weight data in NASS. Finally, THOR50 stimuli were estimated via field simulations involving attendant representative restraint systems, and those stimuli were then assigned to corresponding NASS cases (n=508). For the PMHS portion of the analysis, simulation-based closure equations were developed to convert PMHS stimuli into THOR50 stimuli. Specifically, closure equations were derived for the four measurement locations on the THOR50 chest by cross-correlating the results of matched-loading simulations between the test dummy and the age-dependent, Ford Human Body Model. The resulting closure equations demonstrated acceptable fidelity (n=75 matched simulations, R2≥0.99). These equations were applied to the THOR50-sized men in the PMHS dataset (n=20). The NASS and PMHS datasets were combined and subjected to survival

  18. Evaluation by the Double Loop Electrochemical Potentiokinetic Reactivation Test of Aged Ferritic Stainless Steel Intergranular Corrosion Susceptibility

    NASA Astrophysics Data System (ADS)

    Sidhom, H.; Amadou, T.; Braham, C.

    2010-12-01

    An experimental design method was used to determine the effect of factors that significantly affect the response of the double loop-electrochemical potentiokinetic reactivation (DL-EPR) test in controlling the susceptibility to intergranular corrosion (IGC) of UNS S43000 (AISI 430) ferritic stainless steel. The test response is expressed in terms of the reactivation/activation current ratio ( I r / I a pct). Test results analysed by the analysis of variance (ANOVA) method show that the molarity of the H2SO4 electrolyte and the potential scanning rate have a more significant effect on the DL-EPR test response than the temperature and the depassivator agent concentration. On the basis of these results, a study was conducted in order to determine the optimal operating conditions of the test as a nondestructive technique for evaluating IGC resistance of ferritic stainless steel components. Three different heat treatments are considered in this study: solution annealing (nonsensitized), aging during 3 hours at 773 K (500 °C) (slightly sensitized), and aging during 2 hours at 873 K (600 °C) (highly sensitized). The aim is to find the operating conditions that simultaneously ensure the selectivity of the attack (intergranular and chromium depleted zone) and are able to detect the effect of low dechromization. It is found that a potential scanning rate of 2.5 mV/s in an electrolyte composed of H2SO4 3 M solution without depassivator, at a temperature around 293 K (20 °C), is the optimal operating condition for the DL-EPR test. Using this condition, it is possible to assess the degree of sensitization (DOS) to the IGC of products manufactured in ferritic stainless steels rapidly, reliably, and quantitatively. A time-temperature-start of sensitization (TTS) diagram for the UNS S43000 (France Inox, Villepinte, France) stainless steel was obtained with acceptable accuracy by this method when the IGC sensitization criterion was set to I r / I a > 1 pct. This diagram is in

  19. Damage Assessment of Creep Tested and Thermally Aged Metallic Alloys Using Acousto-Ultrasonics

    NASA Technical Reports Server (NTRS)

    Gyekenyesi, Andrew L.; Kautz, Harold E.; Baaklini, George Y.

    2001-01-01

    In recent years emphasis has been placed on the early detection of material changes experienced in turbine powerplant components. During the scheduled overhaul of a turbine, the current techniques of examination of various hot section components aim to find flaws such as cracks, wear, and erosion, as well as excessive deformations. Thus far, these localized damage modes have been detected with satisfactory results. However, the techniques used to find these flaws provide no information on life until the flaws are actually detected. Major improvements in damage assessment, safety, as well as more accurate life prediction could be achieved if nondestructive evaluation (NDE) techniques could be utilized to sense material changes that occur prior to the localized defects mentioned. Because of elevated temperatures and excessive stresses, turbine components may experience creep behavior. As a result, it is desirable to monitor and access the current condition of such components. Research at the NASA Glenn Research Center involves developing and utilizing an NDE technique that discloses distributed material changes that occur prior to the localized damage detected by the current methods of inspection. In a recent study, creep processes in a nickel-base alloy were the life-limiting condition of interest, and the NDE technique was acousto-ultrasonics (AU). AU is an NDE technique that utilizes two ultrasonic transducers to interrogate the condition of a test specimen. The sending transducer introduces an ultrasonic pulse at a point on the surface of the specimen while a receiving transducer detects the signal after it has passed through the material. The goal of the method is to correlate certain parameters of the detected waveform to characteristics of the material between the two transducers. Here, the waveform parameter of interest is the attenuation due to internal damping for which information is being garnered from the frequency domain. The parameters utilized to

  20. Green and early age compressive strength of extruded cement mortar monitored with compression tests and ultrasonic techniques

    SciTech Connect

    Voigt, Thomas . E-mail: mail@tvoigt.com; Malonn, Tim; Shah, Surendra P.

    2006-05-15

    Knowledge about the early age compressive strength development of cementitious materials is an important factor for the progress and safety of many construction projects. This paper uses cylindrical mortar specimens produced with a ram extruder to investigate the transition of the mortar from plastic and deformable to hardened state. In addition, wave transmission and reflection measurements with P- and S-waves were conducted to obtain further information about the microstructural changes during the setting and hardening process. The experiments have shown that uniaxial compression tests conducted on extruded mortar cylinders are a useful tool to evaluate the green strength as well as the initiation and further development of the compressive strength of the tested material. The propagation of P-waves was found to be indicative of the internal structure of the tested mortars as influenced, for example, by the addition of fine clay particles. S-waves used in transmission and reflection mode proved to be sensitive to the inter-particle bonding caused by the cement hydration and expressed by an increase in compressive strength.

  1. Propeller design: extension of test data on a family of model propellers by means of the modified blade element theory II

    NASA Technical Reports Server (NTRS)

    Weick, Fred E

    1926-01-01

    This report is the second of a series of four on propeller design, and describes the method used to extend the data obtained from tests on a family of thirteen model propellers to include all propellers of the same form likely to be met in practice. This necessitates the development of a method of propeller analysis which when used to calculate the powers and efficiencies gives results which check the tests throughout their range.

  2. Are Morphometrics Sufficient for Estimating Age of Pre-Fledging Birds in the Field? A Test Using Common Terns (Sterna hirundo)

    PubMed Central

    Wails, Christy N.; Oswald, Stephen A.; Arnold, Jennifer M.

    2014-01-01

    Age is a key component of fitness, affecting survival and reproductive capacities. Where it is not possible to study known individuals from birth, morphometrics (predominantly patterns of plumage development for birds) are most often used to estimate age. Although criteria for age estimations exist for many species, the degree to which these criteria improve the precision of estimates remains to be tested, restricting their widespread acceptance. We develop a photographic tool for estimating ages of Common Tern (Sterna hirundo) chicks and test it using 100 human observers of varying prior experience across four breeding colonies (three North American sites and one European site) and under controlled laboratory conditions. We followed the design approach of other morphometric tools, expanding it to create a user-friendly guide (divided into six age groupings). The majority (86%) of observers improved in chick-aging accuracy when using the tool by an average of 20.1% (±1.4 SE) and correctly estimated 60.3% (±1.4) of chick ages. This was similar to the intrinsic aging ability of our best field observer (63.3%). Observers with limited experience showed the greatest increases in chick-aging accuracy over experienced observers who likely had established a method for estimating chick ages prior to using the tool. Even the best observers only correctly estimated ages of chicks 62.9% (±2.8) of the time in the field and 84.0% (±2.9) of the time in the lab when using the tool and typically underestimated ages. This indicates that developmental variation between individual chicks can prevent completely reliable age estimates and corroborates the few existing data that suggest that morphometric criteria fail to achieve robust levels of accuracy and may introduce error into studies that rely on them. We conclude that novel approaches for estimating age, not only morphometric criteria, must be pursued. PMID:25375105

  3. The new age of play audiometry: prospective validation testing of an iPad-based play audiometer

    PubMed Central

    2013-01-01

    Objective The timely diagnosis of hearing loss in the pediatric population has significant implications for a child’s development. However, audiological evaluation in this population poses unique challenges due to difficulties with patient cooperation. Though specialized adaptations exist (such as conditioned play audiometry), these methods can be time consuming and costly. The objective of this study was to validate an iPad-based play audiometer that addresses the shortcomings of existing audiometry. Methods We designed a novel, interactive game for the Apple® iPad® that tests pure tone thresholds. In a prospective, randomized study, the efficacy of this tool was compared to standard play audiometry. 85 consecutive patients presenting to the Audiology Clinic at the Children’s Hospital of Eastern Ontario (ages 3 and older) were recruited into this study. Their hearing was evaluated using both tablet and traditional play audiometry. Outcome measure Warble-tone thresholds obtained by both tablet and traditional audiometry. Results The majority of children in this age group were capable of completing an audiologic assessment using the tablet computer. The data demonstrate no statistically significant difference between warble-tone thresholds obtained by tablet and traditional audiometry (p=0.29). Moreover, the tablet audiometer demonstrates strong sensitivity (93.3%), specificity (94.5%) and negative predictive value (98.1%). Conclusion The tablet audiometer is a valid and sensitive instrument for screening and assessment of warble-tone thresholds in children. PMID:23663317

  4. Commitment in Age-Gap Heterosexual Romantic Relationships: A Test of Evolutionary and Socio-Cultural Predictions

    ERIC Educational Resources Information Center

    Lehmiller, Justin J.; Agnew, Christopher R.

    2008-01-01

    Little research has addressed age-gap romantic relationships (romantic involvements characterized by substantial age differences between partners). Drawing on evolutionary and socio-cultural perspectives, the present study examined normative beliefs and commitment processes among heterosexual women involved in age-gap and age-concordant…

  5. Role of Sexual Objectification Experiences and Internalization of Standards of Beauty in Eating Disorder Symptomatology: A Test and Extension of Objectification Theory

    ERIC Educational Resources Information Center

    Moradi, Bonnie; Dirks, Danielle; Matteson, Alicia V.

    2005-01-01

    This study extends the literature on eating disorder symptomatology by testing, based on extant literature on objectification theory (B. L. Fredrickson & T. Roberts, 1997) and the role of sociocultural standards of beauty (e.g., L. J. Heinberg, J. K. Thompson, & S. Stormer, 1995), a model that examines (a) links of reported sexual objectification…

  6. Extension of in-situ stress test analysis to rapid hole evacuation at Yucca Mountain due to a network of open conduits

    SciTech Connect

    Davies, J.B.

    1994-01-01

    Yucca Mountain is underlain by tuffaceous rocks that are highly fractured and jointed. During drilling of bore-holes at Yucca Mountain there were numerous occurrences of lost circulation when whole mud was taken by the formation. This evidence suggests that parts of Yucca Mountain are controlled hydrologicaly by a network of open conduits along the existing joints and fractures. Also at Yucca Mountain, stress tests have been performed in-situ by charging a small section along the boreholes with an excess pressure head of water. For many of these tests, the initial drop in water head was so rapid that within seconds up to hundreds of meters of fall had occurred. The opening of fractures as the excess head increases has previously been proposed as an important factor in explaining the shape of the stress test curves at lower pressures. We propose that such induced hydraulic fractures, under increasing water heads, can grow to a length sufficient to intersect the existing network of open joints and fractures. We extend our previous model to incorporate flow out along these open conduits and examine the initial rapid drop in terms of these extended models. We show that this rapid evacuation model fits the observed data from many slug tests in wells in the vicinity of Yucca Mountain. This result is confirmation of the drilling evidence that a network of open conduits exists at various depths below the water table and over a large geographic region around Yucca Mountain.

  7. A test of the differential accuracy of the maxillary versus the mandibular dentition in age estimations of immature skeletal remains based on developing tooth length.

    PubMed

    Cardoso, Hugo F V

    2007-03-01

    Liversidge and colleagues developed a method for predicting the age of immature skeletal remains based on the length of developing teeth. This quantitative method combines dental data from both jaws, except for the permanent lateral incisor, and because there are reasons to suspect that these two types of data are not identical and should not be combined, it raises concerns regarding the accuracy of the technique when applied differently to each jaw. In this study, the differential accuracy of the method was test when applied to the maxillary and mandibular dentition. The test sample is comprised of 57 Portuguese subadult skeletons of known age at death. Results suggest an overall high consistency between estimates obtained from both jaws, but for the permanent dentition only. In the deciduous dentition the age estimates obtained from the maxillary teeth tend to be greater than the age estimates obtained from the mandibular pair, and the differences are significant for the incisors and canine. Additionally, ages obtained from the maxillary deciduous canine also differ significantly from true chronological age. In the permanent dentition there were no differences between the ages provided by both jaws but both the maxillary and mandibular second molars show a significant tendency to underestimate true chronological age. Although this study cannot validate completely the method presented by Liversidge and colleagues, it does provide an important test to its accuracy and calls for further research into its overall performance, particularly with respect to the results obtained from both jaws. PMID:17316246

  8. Using oxygen isotopes to quantitatively assess residual CO2 saturation during the CO2CRC Otway Stage 2B Extension residual saturation test

    NASA Astrophysics Data System (ADS)

    Serno, Sascha; Johnson, Gareth; LaForce, Tara C.; Ennis-King, Jonathan; Haese, Ralf; Boreham, Chris; Paterson, Lincoln; Freifeld, Barry M.; Cook, Paul J.; Kirste, Dirk; Haszeldine, R. Stuart; Gilfillan, Stuart M. V.

    2016-04-01

    Recent research has shown that the oxygen isotope ratio (δ18O) of reservoir water can change due to isotopic equilibrium exchange with injected CO2. These changes have been successfully used to assess reservoir saturation with CO2. We present the first δ18O measurements from a single-well experiment, the CO2CRC Otway 2B Extension project, used to estimate levels of residual trapping of CO2. Following the initiation of the drive to residual saturation in the reservoir, reservoir water δ18O decreased, as predicted from the baseline isotope ratios of water and CO2, over a time span of only a few days. The isotope shift in the near-wellbore reservoir water is the result of isotope equilibrium exchange between residual CO2 and water. For the region further away from the well, the isotopic shift in the reservoir water can also be explained by isotopic exchange with mobile CO2 from ahead of the region driven to residual, or continuous isotopic exchange between water and residual CO2 during its back-production, complicating the interpretation of the change in reservoir water δ18O in terms of residual saturation. A small isotopic distinction of the baseline water and CO2 δ18O, together with issues encountered during the field experiment procedure, further prevents the estimation of residual CO2 saturation levels from oxygen isotope changes without significant uncertainty. The consistency of oxygen isotope-based near-wellbore saturation levels and independent estimates based on pulsed neutron logging indicates the potential of using oxygen isotope as an effective inherent tracer for determining residual saturation on a field scale within a few days.

  9. Detection of 2009 pandemic influenza A(H1N1) virus Infection in different age groups by using rapid influenza diagnostic tests

    PubMed Central

    Gao, Fengxiang; Loring, Carol; Laviolette, Michael; Bolton, Denise; Daly, Elizabeth R.; Bean, Christine

    2011-01-01

    Please cite this paper as: Gao et al. (2011) Detection of 2009 pandemic influenza A(H1N1) virus Infection in different age groups by using rapid influenza diagnostic tests. Influenza and Other Respiratory Viruses 6(3), e30–e34. Background  The performance of rapid influenza diagnostic tests (RIDTs) in detecting influenza A(H1N1) 2009 has varied widely. Evaluations of RIDTs among infected individuals across all age groups have not been described in depth. Objectives  Determine RIDT clinical sensitivity in comparison with influenza detection using real‐time RT‐PCR among patients infected with influenza A(H1N1) 2009 across all age groups. Study design  This study analyzed respiratory specimens received by the New Hampshire Public Health Laboratories (NHPHL) from September 1, 2009, through December 31, 2009. RIDT performance was evaluated among different age groups of patients determined to be infected with influenza A (H1N1) 2009, and the association between age and RIDT sensitivity was determined. Results  Of 1373 specimens examined, 269 tested positive for influenza A(H1N1) 2009 by real‐time RT‐PCR (rRT‐PCR) and had RIDT results available. Overall clinical sensitivity and specificity of RIDTs were 53·9 and 98·5%, respectively. By age group, clinical sensitivity was 85·7% in patients <2 years old, 60·3% in patients between 2‐ and 39 years old, and 33·3% in patients aged 40 and older. Logistic regression analysis indicated that increasing age was negatively associated with RIDT performance. Conclusion  Rapid influenza diagnostic test sensitivity decreased significantly with increasing age. Findings from this study may impact a clinician’s interpretation of RIDT test results and ultimately have implications in clinical decision‐making. PMID:22114876

  10. Extensive quantities in thermodynamics

    NASA Astrophysics Data System (ADS)

    Mannaerts, Sebastiaan H.

    2014-05-01

    A literature survey shows little consistency in the definitions of the term ‘extensive quantity’ (a.k.a. extensive property) as used in thermodynamics. A majority assumes that extensive quantities are those that are proportional to mass. Taking the mathematical meaning of proportional and taking the ‘mass’ to be that of the system or subsystem, it is shown that the proportionality assumption is only correct for a few extensive quantities under condition of constant composition. A large subset of extensive quantities are completely independent of mass; for most systems extensive quantities are not proportional to mass, but mass is the (extensive) constant of proportionality. The definition by IUPAC, based on the additivity of extensive quantities, is the preferred baseline for discussing this subject. It is noted however, that two types of additivity need to be distinguished and that a few intensive quantities are also additive. This paper leaves several interesting questions open to further scrutiny.

  11. HIV testing and attitudes among the working-age population of Japan: annual health checkups may offer an effective way forwards

    PubMed Central

    ISHIMARU, Tomohiro; WADA, Koji; SMITH, Derek R

    2015-01-01

    In Japan, Voluntary Counselling and Testing (VCT) for HIV has been recommended for people concerned about their infection risk, especially those in high-risk groups. Although HIV awareness has declined in this country somewhat during recent years, the number of newly-infected cases has been increasing. The purpose of the current study therefore, was to determine the prevalence of HIV testing, individuals’ reasons for being tested, and the overall acceptance of HIV testing among working-age Japanese. We utilized an anonymous, nationwide survey which was administered to a total of 3,055 participants aged 20–69 yr. The lifetime prevalence of HIV testing was 14% (2% within the past year). A gap was observed between a prior history of HIV testing and willingness to be tested in future (32%) or willingness to be tested during health checkups in the workplace (41%). HIV testing appears to have only been conducted among a limited number of working-age Japanese adults, even though some reported a willingness to be tested. Opportunities for VCT during workplace health checkups might offer an immediate and positive way forwards in the fight against HIV; however, privacy protection for test results and the acceptance of HIV-positive employees should be carefully considered in the workplace. PMID:26423333

  12. Interfacial Reactions of Zn-Al Alloys with Na Addition on Cu Substrate During Spreading Test and After Aging Treatments

    NASA Astrophysics Data System (ADS)

    Gancarz, Tomasz; Pstruś, Janusz; Berent, Katarzyna

    2016-04-01

    Spreading tests for Cu substrate with Zn-Al eutectic-based alloys with 0.2, 0.5, and 1.0 wt.% of Na were studied using the sessile drop method in the presence of QJ201 flux. Spreading tests were performed for 1, 3, 8, 15, 30, and 60 min of contact, at the temperatures of 475, 500, 525, and 550 °C. After cleaning the flux residue from solidified samples, the spreading area of Zn-Al + Na on Cu was determined in accordance with ISO 9455-10:2013-03. Selected, solidified solder-substrate couples were cross-sectioned and subjected to scanning electron microscopy of the interfacial microstructure. The experiment was designed to demonstrate the effect of Na addition on the kinetics of formation and growth of CuZn, Cu5Zn8, and CuZn4 phases, which were identified using x-ray diffraction and energy-dispersive spectroscopy analysis. The addition of Na to eutectic Zn-Al caused the spreading area to decrease and the thickness of intermetallic compound layers at the interface to reduce. Samples after the spreading test at 500 °C for 1 min were subjected to aging for 1, 10, and 30 days at 120,170, and 250 °C. The greater thicknesses of IMC layers were obtained for a temperature of 250 °C. With increasing Na content in Zn-Al + Na alloys, the thickness reduced, which correlates to the highest value of activation energy for Zn-Al with 1% Na.

  13. Gerontology Information and Training Needs of Cooperative Extension Professionals.

    ERIC Educational Resources Information Center

    Nichols, Allison; Howard, Sally

    2002-01-01

    Data from 50 state extension websites, an aging specialist survey (n=30), and extension faculty needs assessment (n=51) revealed the scope of gerontology in Cooperative Extension. Faculty were interested in training on program design and information on health issues. County extension agents were particularly interested in resources for this…

  14. The Cooperative Extension Service.

    ERIC Educational Resources Information Center

    Sanders, H. C., Ed.

    Designed to stimulate and support training for Extension work and to orient new employees, this book covers the Cooperative Extension Service (CES) and its methods of operation. It begins by describing the status of rural extension in the United States and abroad; the history of the CES and its antecendents; the legal basis, scope, functions, and…

  15. Epidemiology of Schistosomiasis and Usefulness of Indirect Diagnostic Tests in School-Age Children in Cubal, Central Angola

    PubMed Central

    Bocanegra, Cristina; Gallego, Sara; Mendioroz, Jacobo; Moreno, Milagros; Sulleiro, Elena; Salvador, Fernando; Sikaleta, Nicolau; Nindia, Arlette; Tchipita, Daniel; Joromba, Morais; Kavaya, Sebastiao; Sánchez Montalvá, Adrián; López, Teresa; Molina, Israel

    2015-01-01

    Introduction Schistosomiasis remains a public health major problem and little is known in many areas, mainly in Sub-Saharan Africa Objectives To assess the burden and risk factors of schistosomiasis and intestinal parasitic helminthes in the children of Cubal, Angola, and to compare different diagnostic approaches for urinary schistosomiasis under field conditions. Methods A cross-sectional study was conducted. Urine and faeces samples of school children were microscopically studied. A random sample of children was obtained from an alphabetically arranged list of children, taking one of two children. Urine dipstick, colorimetric test and macrohaematuria were considered as indirect diagnostic methods and compared to direct urine examination. Possible risk factors for the infection were sex, age, distance to the river and previous treatment with praziquantel; the assessment was performed using Chi-square test. Results A total of 785 (61.18%) children showed S. haematobium eggs in urine; children living within 500 meters from the river had a higher odds for infection: Odds ratio 1.97 (1.45–2.7 CI 95%); urine dipstick showed sensitivity of 96% and specificity of 61.3%, with a positive predictive value; colorimetric test showed sensitivity of 52.5%, specificity of 74.6% and a positive predictive value of 77%. Proteinuria was present in 653 (51.1%) children, being more frequent in children with S. haematobium in urine (75.2%); 32 of 191 stool samples (16%) showed the presence of other intestinal parasites and 8 (4%) for S. haematobium. Conclusions Prevalence of urinary schistosomiasis in our study area is much higher than the national average, considering it as a high-risk community. Proximity to a source of water was a risk factor for the infection. Indirect tests, as urine dipstick and colorimetric test, were useful tools for diagnosis, due to ease of use and low cost. Proteinuria was a common finding, probably showing an early structural damage due to

  16. Prevalence of Helicobacter Pylori Infection in School and Pre-School Aged Children with C-14 Urea Breath Test and the Association with Familial and Environmental Factors

    PubMed Central

    Çınar, Alev; Sadıç, Murat; İkbal Atılgan, Hasan; Baskın, Aylin; Koca, Gökhan; Demirel, Koray; Korkmaz, Meliha

    2015-01-01

    Objective: To investigate the prevalence of Helicobacter pylori (Hp) infection in pre-school and school age children with C-14 urea breath test, and to explore its association with age and socioeconomic factors in Turkey. Methods: Hp infection status was determined by using Urea Breath Test (UBT). Patients who had previous gastric surgery, Hp eradication treatment or equivocal UBT results were excluded. A questionnaire was administered to elicit information on gender, age, ABO/Rh blood group type, presence of gastric disease in the family, domestic animal in the household, and treatment for idiopathic Iron Deficiency Anemia (IDA). Results: This retrospective study included 500 pediatric patients (179 boys, 321 girls, mean age 10.7±4.3 years) of whom 62 (12.4%) were aged ≤6 years and 438 (87.6%) were aged 7 to 16 years. Helicobacter pylori (Hp) was positive in 245 (49%) cases. In the pre-school age group, 21/62 cases (34%) had positive UBT while in the school age group 224/438 children (51%) had positive UBT. A family history of dyspepsia and pet ownership were not associated with Hp positivity. Hp positive 76 (29.8%) children were on IDA treatment but this was not statistically significant. Conclusion: The Hp infection positivity rate was 49% in the pediatric age study group. The positivity rate was significantly lower at preschool age than school age, and it increased with age. There was no association with gender, ABO/Rh blood groups, presence of domestic pets, IDA, or history of gastric disease in the family. PMID:26316471

  17. Slope Extensions to ASL Library

    Energy Science and Technology Software Center (ESTSC)

    2010-03-31

    Extensions to the AMPL/solver interface library (http://netlib.sandia.gov/ampl/solvers) to compute bounds on algebraic expressions, plus a test program. use in uncertainty quantification and global optimization algorithms. This software is not primarily for military applications.

  18. Dynamic mechanical and molecular weight measurements on polymer bonded explosives from thermally accelerated aging tests. I. Fluoropolymer binders

    SciTech Connect

    Hoffman, D.M.; Caley, L.E.

    1981-01-01

    The dynamic mechanical properties and molecular weight distribution of two polymer bonded explosives, LX-10-1 and PBX-9502, maintained at 23, 60, and 74/sup 0/C for 3 years were studied. LX-10-1 is 94.5% 1,3,5,7-tetranitro-1,3,5,7-tetraazacyclooctane explosive bonded together with 5.5% Viton A fluoropolymer. PBX-9502 is 95% triaminotrinitrobenzene explosive bonded with 5% Kel-F-800 fluoropolymer. There are two mechanical relaxations in the LX-10-1 in the military temperature range. The relaxation at -10/sup 0/C is associated with the glass transition temperature of the Viton A binder. A second weak relaxation occurs at about 30/sup 0/C in all LX-10-1 samples tested. This relaxation is probably associated with small amounts of crystallinity in the binder although this has not been demonstrated. There is a slight increase in modulus of the LX-10-1 with accelerated aging temperature. Changes in the dynamic mechanical properties of PBX-9502 are ascribed to crystallization of the chlorotrifluoroethylene component of the Kel-F-800 binder. The molecular weight of the Viton A binder decreased slight with increasing aging temperature. Using the kinetics of random scission the activation energy for polymer degradation in the presence of the explosive was 1.19 kcal/mole. The Arrhenius preexponential term and activation energy predict an expected use-life in excess of 60 years for LX-10-1. The Kel-F-800 in PBX-9502 is also extremely stable.

  19. Cooled artery extension

    NASA Technical Reports Server (NTRS)

    Gernert, Nelson J. (Inventor)

    1990-01-01

    An artery vapor trap. A heat pipe artery is constructed with an extension protruding from the evaporator end of the heat pipe beyond the active area of the evaporator. The vapor migrates into the artery extension because of gravity or liquid displacement, and cooling the extension condenses the vapor to liquid, thus preventing vapor lock in the working portion of the artery by removing vapor from within the active artery. The condensed liquid is then transported back to the evaporator by the capillary action of the artery extension itself or by wick located within the extension.

  20. Behavior in the elevated plus maze is differentially affected by testing conditions in rats under and over three weeks of age.

    PubMed

    Albani, Sarah H; Andrawis, Marina M; Abella, Rio Jeane H; Fulghum, John T; Vafamand, Naghmeh; Dumas, Theodore C

    2015-01-01

    The late postnatal period in rats is marked by numerous changes in perceptual and cognitive abilities. As such, age-related variation in cognitive test performance might result in part from disparate sensitivities to environmental factors. To better understand how testing conditions might interact with age, we assessed anxiety behavior on an elevated plus maze (EPM) in juvenile rats around 3 weeks of age under diverse testing conditions. Plasma corticosterone and neuronal activation patterns in the forebrain were examined after maze exposure. We found that anxiety was differentially expressed during different stages of late postnatal development. Bright illumination and morning testing encouraged greatest open arm exploration on the EPM in younger animals, while older rats explored open areas more under dim illumination in the morning compared to bright illumination in the afternoon/evening. Older rats exhibited higher plasma corticosterone levels at baseline compared to younger rats; however, this trend was reversed for post-testing corticosterone. Additionally, post-testing corticosterone levels were inversely related to time of testing. Compared to testing in the morning, EPM exposure in the afternoon/evening elicited greater neuronal Arc expression in the amygdala. Arc expression in the amygdala after morning testing was greater at P22-24 than P17-19. In layer 2/3 of primary visual cortex, Arc expression was elevated in younger animals and age interacted with time of testing to produce opposing effects at P17-19 and P22-24. These data suggest that age-related differences in anxiety-associated behavior during the late postnatal period are due in part to changes in light sensitivity and emergence of a circadian cycle for corticosterone. The findings illustrate that late postnatal behavioral development in rodents is a complex orchestration of changes in neural systems involved in perception, cognition, affect and homeostatic regulation. PMID:25741257

  1. Behavior in the elevated plus maze is differentially affected by testing conditions in rats under and over three weeks of age

    PubMed Central

    Albani, Sarah H.; Andrawis, Marina M.; Abella, Rio Jeane H.; Fulghum, John T.; Vafamand, Naghmeh; Dumas, Theodore C.

    2015-01-01

    The late postnatal period in rats is marked by numerous changes in perceptual and cognitive abilities. As such, age-related variation in cognitive test performance might result in part from disparate sensitivities to environmental factors. To better understand how testing conditions might interact with age, we assessed anxiety behavior on an elevated plus maze (EPM) in juvenile rats around 3 weeks of age under diverse testing conditions. Plasma corticosterone and neuronal activation patterns in the forebrain were examined after maze exposure. We found that anxiety was differentially expressed during different stages of late postnatal development. Bright illumination and morning testing encouraged greatest open arm exploration on the EPM in younger animals, while older rats explored open areas more under dim illumination in the morning compared to bright illumination in the afternoon/evening. Older rats exhibited higher plasma corticosterone levels at baseline compared to younger rats; however, this trend was reversed for post-testing corticosterone. Additionally, post-testing corticosterone levels were inversely related to time of testing. Compared to testing in the morning, EPM exposure in the afternoon/evening elicited greater neuronal Arc expression in the amygdala. Arc expression in the amygdala after morning testing was greater at P22–24 than P17–19. In layer 2/3 of primary visual cortex, Arc expression was elevated in younger animals and age interacted with time of testing to produce opposing effects at P17–19 and P22–24. These data suggest that age-related differences in anxiety-associated behavior during the late postnatal period are due in part to changes in light sensitivity and emergence of a circadian cycle for corticosterone. The findings illustrate that late postnatal behavioral development in rodents is a complex orchestration of changes in neural systems involved in perception, cognition, affect and homeostatic regulation. PMID:25741257

  2. Age-stratified Bayesian analysis to estimate sensitivity and specificity of four diagnostic tests for detection of Cryptosporidium oocysts in neonatal calves.

    PubMed

    De Waele, Valerie; Berzano, Marco; Berkvens, Dirk; Speybroeck, Niko; Lowery, Colm; Mulcahy, Grace M; Murphy, Thomas M

    2011-01-01

    There is no gold standard diagnostic test for the detection of bovine cryptosporidiosis. Infection is usually highest in 2-week-old calves, and these calves also excrete high numbers of oocysts. These factors may give rise to variations in the sensitivity and specificity of the various diagnostic tests used to detect infection in calves of various ages. An age-stratified Bayesian analysis was carried out to determine the optimum diagnostic test to identify asymptomatic and clinical Cryptosporidium sp. infection in neonatal calves. Fecal samples collected from 82 calves at 1 week, 2 weeks, 3 weeks, and 4 weeks of age were subjected to the following tests: microscopic examination of smears stained with either phenol-auramine O or fluorescein isothiocyanate (FITC)-conjugated anti-Cryptosporidium monoclonal antibody, nested-PCR, and quantitative real-time PCR. The results confirmed a high prevalence of Cryptosporidium sp. infection, as well as a high level of oocyst excretion, in 2-week-old calves. The sensitivities of all the tests varied with the age of the calves. Quantitative real-time PCR proved to be the most sensitive and specific test for detecting infection irrespective of the age of the calf. The microscopic techniques were the least sensitive and exhibited only moderate efficiency with 2-week-old calves excreting large numbers of oocysts, the majority of which were diarrheic. It was concluded that, when interpreting the results of routine tests for bovine cryptosporidiosis, cognizance should be taken of the sensitivity of the tests in relation to the age of the calves and stage of infection. PMID:21048012

  3. A Sample of Very Young Field L Dwarfs and Implications for the Brown Dwarf "Lithium Test" at Early Ages

    NASA Astrophysics Data System (ADS)

    Kirkpatrick, J. Davy; Cruz, Kelle L.; Barman, Travis S.; Burgasser, Adam J.; Looper, Dagny L.; Tinney, C. G.; Gelino, Christopher R.; Lowrance, Patrick J.; Liebert, James; Carpenter, John M.; Hillenbrand, Lynne A.; Stauffer, John R.

    2008-12-01

    Using a large sample of optical spectra of late-type dwarfs, we identify a subset of late-M through L field dwarfs that, because of the presence of low-gravity features in their spectra, are believed to be unusually young. From a combined sample of 303 field L dwarfs, we find observationally that 7.6% +/- 1.6% are younger than 100 Myr. This percentage is in agreement with theoretical predictions once observing biases are taken into account. We find that these young L dwarfs tend to fall in the southern hemisphere (decl . < 0°) and may be previously unrecognized, low-mass members of nearby, young associations like Tucana-Horologium, TW Hydrae, β Pictoris, and AB Doradus. We use a homogeneously observed sample of ~150 optical spectra to examine lithium strength as a function of L/T spectral type and further corroborate the trends noted by Kirkpatrick and coworkers. We use our low-gravity spectra to investigate lithium strength as a function of age. The data weakly suggest that for early- to mid-L dwarfs the line strength reaches a maximum for a few × 100 Myr, whereas for much older (few Gyr) and much younger (<100 Myr) L dwarfs the line is weaker or undetectable. We show that a weakening of lithium at lower gravities is predicted by model atmosphere calculations, an effect partially corroborated by existing observational data. Larger samples containing L dwarfs of well-determined ages are needed to further test this empirically. If verified, this result would reinforce the caveat first cited by Kirkpatrick and coworkers that the lithium test should be used with caution when attempting to confirm the substellar nature of the youngest brown dwarfs. Most of the spectroscopic data presented herein were obtained at the W. M. Keck Observatory, which is operated as a scientific partnership among the California Institute of Technology, the University of California, and the National Aeronautics and Space Administration. The Observatory was made possible by the generous

  4. Older age is associated with greater central aortic blood pressure following the exercise stress test in subjects with similar brachial systolic blood pressure.

    PubMed

    Kobayashi, Masatake; Oshima, Kazutaka; Iwasaki, Yoichi; Kumai, Yuto; Avolio, Alberto; Yamashina, Akira; Takazawa, Kenji

    2016-08-01

    Brachial systolic pressure (BSP) is often monitored during exercise by the stress test; however, central systolic pressure (CSP) is thought to be a more direct measure of cardiovascular events. Although some studies reported that exercise and aging may play roles in changes of both BSP and CSP, the relationship between BSP and CSP with age following the exercise stress test remains unclear. The aim of this study was to evaluate the effect of age on the relationship between BSP and CSP measured after exercise. Ninety-six subjects underwent the diagnostic treadmill exercise stress test, and we retrospectively divided them into the following 3 groups by age: the younger age group (43 ± 4 years), middle age group (58 ± 4 years), and older age group (70 ± 4 years). Subjects exercised according to the Bruce protocol, to achieve 85 % of their age-predicted maximum heart rate or until the appearance of exercise-associated symptoms. BSP, CSP, and pulse rate (PR) were measured using a HEM-9000AI (Omron Healthcare, Japan) at rest and after exercise. BSP, CSP, and PR at rest were not significantly different among the 3 groups (p = 0.92, 0.21, and 0.99, respectively). BSP and PR immediately after exercise were not significantly different among the groups (p = 0.70 and 0.38, respectively). However, CSP immediately after exercise was 144 ± 18 mmHg (younger age), 149 ± 17 mmHg (middle age), and 158 ± 19 mmHg (older age). CSP in the older age group was significantly higher than that in the younger age group (p < 0.01). Despite similar BSPs in all age groups after exercise, CSP was higher in the older age group. Therefore, older subjects have a higher CSP after exercise, which is not readily assessed by conventional measurements of BSP. PMID:26293569

  5. A Method for Calculating the Heat Required for Windshield Thermal Ice Prevention Based on Extensive Flight Tests in Natural Icing Conditions

    NASA Technical Reports Server (NTRS)

    Jones, Alun R; Holdaway, George H; Steinmetz, Charles P

    1947-01-01

    An equation is presented for calculating the heat flow required from the surface of an internally heated windshield in order to prevent the formation of ice accretions during flight in specified icing conditions. To ascertain the validity of the equation, comparison is made between calculated values of the heat required and measured values obtained for test windshields in actual flights in icing conditions. The test windshields were internally heated and provided data applicable to two common types of windshield configurations; namely the V-type and the type installed flush with the fuselage contours. These windshields were installed on a twin-engine cargo airplane and the icing flights were conducted over a large area of the United States during the winters of 1945-46 and 1946-47. In addition to the internally heated windshield investigation, some test data were obtained for a windshield ice-prevention system in which heated air was discharged into the windshield boundary layer. The general conclusions resulting from this investigation are as follows: 1) The amount of heat required for the prevention of ice accretions on both flush- and V-type windshields during flight in specified icing conditions can be calculated with a degree of accuracy suitable for design purposes. 2) A heat flow of 2000 to 2500 Btu per hour per square foot is required for complete and continuous protection of a V-type windshield in fight at speeds up to 300 miles per hour in a moderate cumulus icing condition. For the same degree of protection and the same speed range, a value of 1000 Btu per hour per square foot suffices in a moderate stratus icing condition. 3) A heat supply of 1000 Btu per hour per square foot is adequate for a flush windshield located well aft of the fuselage stagnation region, at speeds up to 300 miles per hour, for flight in both stratus and moderate cumulus icing conditions. 4) The external air discharge system of windshield thermal ice prevention is thermally

  6. Quantification of Age-Related Tissue-Level Failure Strains of Rat Femoral Cortical Bones Using an Approach Combining Macrocompressive Test and Microfinite Element Analysis.

    PubMed

    Fan, Ruoxun; Gong, He; Zhang, Rui; Gao, Jiazi; Jia, Zhengbin; Hu, Yanjuan

    2016-04-01

    Bone mechanical properties vary with age; meanwhile, a close relationship exists among bone mechanical properties at different levels. Therefore, conducting multilevel analyses for bone structures with different ages are necessary to elucidate the effects of aging on bone mechanical properties at different levels. In this study, an approach that combined microfinite element (micro-FE) analysis and macrocompressive test was established to simulate the failure of male rat femoral cortical bone. Micro-FE analyses were primarily performed for rat cortical bones with different ages to simulate their failure processes under compressive load. Tissue-level failure strains in tension and compression of these cortical bones were then back-calculated by fitting the experimental stress-strain curves. Thus, tissue-level failure strains of rat femoral cortical bones with different ages were quantified. The tissue-level failure strain exhibited a biphasic behavior with age: in the period of skeletal maturity (1-7 months of age), the failure strain gradually increased; when the rat exceeded 7 months of age, the failure strain sharply decreased. In the period of skeletal maturity, both the macro- and tissue-levels mechanical properties showed a large promotion. In the period of skeletal aging (9-15 months of age), the tissue-level mechanical properties sharply deteriorated; however, the macromechanical properties only slightly deteriorated. The age-related changes in tissue-level failure strain were revealed through the analysis of male rat femoral cortical bones with different ages, which provided a theoretical basis to understand the relationship between rat cortical bone mechanical properties at macro- and tissue-levels and decrease of bone strength with age. PMID:26902102

  7. Results of the IEA Round Robin on Viscosity and Aging of Fast Pyrolysis Bio-oils: Long-Term Tests and Repeatability

    SciTech Connect

    Elliott, Douglas C.; Oasmaa, Anja; Meier, Dietrich; Preto, Fernando; Bridgwater, Anthony V.

    2012-11-06

    An international round robin study of the viscosity and aging of fast pyrolysis bio-oil has been undertaken recently and this work is an outgrowth from that effort. Two bio-oil samples were distributed to the laboratories for aging tests and extended viscosity studies. The accelerated aging test was defined as the change in viscosity of a sealed sample of bio-oil held for 24 h at 80 °C. The test was repeated 10 times over consecutive days to determine the repeatability of the method. Other bio-oil samples were placed in storage at three temperatures, 21 °C, 4 °C and -17 °C for a period up to a year to evaluate the change in viscosity. The variation in the results of the aging test was shown to be low within a given laboratory. Storage of bio-oil under refrigeration can minimize the amount of change in viscosity. The accelerated aging test gives a measure of change similar to that of 6-12 months of storage at room temperature. These results can be helpful in setting standards for use of bio-oil, which is just coming into the marketplace.

  8. Rungs 1 to 4 of DFT Jacob's ladder: Extensive test on the lattice constant, bulk modulus, and cohesive energy of solids.

    PubMed

    Tran, Fabien; Stelzl, Julia; Blaha, Peter

    2016-05-28

    A large panel of old and recently proposed exchange-correlation functionals belonging to rungs 1 to 4 of Jacob's ladder of density functional theory are tested (with and without a dispersion correction term) for the calculation of the lattice constant, bulk modulus, and cohesive energy of solids. Particular attention will be paid to the functionals MGGA_MS2 [J. Sun et al., J. Chem. Phys. 138, 044113 (2013)], mBEEF [J. Wellendorff et al., J. Chem. Phys. 140, 144107 (2014)], and SCAN [J. Sun et al., Phys. Rev. Lett. 115, 036402 (2015)] which are meta-generalized gradient approximations (meta-GGA) and are developed with the goal to be universally good. Another goal is also to determine for which semilocal functionals and groups of solids it is beneficial (or not necessary) to use the Hartree-Fock exchange or a dispersion correction term. It is concluded that for strongly bound solids, functionals of the GGA, i.e., rung 2 of Jacob's ladder, are as accurate as the more sophisticated functionals of the higher rungs, while it is necessary to use dispersion corrected functionals in order to expect at least meaningful results for weakly bound solids. If results for finite systems are also considered, then the meta-GGA functionals are overall clearly superior to the GGA functionals. PMID:27250292

  9. Extensive database of liquid phase diffusion coefficients of some frequently used test molecules in reversed-phase liquid chromatography and hydrophilic interaction liquid chromatography.

    PubMed

    Song, Huiying; Vanderheyden, Yoachim; Adams, Erwin; Desmet, Gert; Cabooter, Deirdre

    2016-07-15

    Diffusion plays an important role in all aspects of band broadening in chromatography. An accurate knowledge of molecular diffusion coefficients in different mobile phases is therefore crucial in fundamental column performance studies. Correlations available in literature, such as the Wilke-Chang equation, can provide good approximations of molecular diffusion under reversed-phase conditions. However, these correlations have been demonstrated to be less accurate for mobile phases containing a large percentage of acetonitrile, as is the case in hydrophilic interaction liquid chromatography. A database of experimentally measured molecular diffusion coefficients of some 45 polar and apolar compounds that are frequently used as test molecules under hydrophilic interaction liquid chromatography and reversed-phase conditions is therefore presented. Special attention is given to diffusion coefficients of polar compounds obtained in large percentages of acetonitrile (>90%). The effect of the buffer concentration (5-10mM ammonium acetate) on the obtained diffusion coefficients is investigated and is demonstrated to mainly influence the molecular diffusion of charged molecules. Diffusion coefficients are measured using the Taylor-Aris method and hence deduced from the peak broadening of a solute when flowing through a long open tube. The validity of the set-up employed for the measurement of the diffusion coefficients is demonstrated by ruling out the occurrence of longitudinal diffusion, secondary flow interactions and extra-column effects, while it is also shown that radial equilibration in the 15m long capillary is effective. PMID:27240944

  10. geneCommittee: a web-based tool for extensively testing the discriminatory power of biologically relevant gene sets in microarray data classification

    PubMed Central

    2014-01-01

    Background The diagnosis and prognosis of several diseases can be shortened through the use of different large-scale genome experiments. In this context, microarrays can generate expression data for a huge set of genes. However, to obtain solid statistical evidence from the resulting data, it is necessary to train and to validate many classification techniques in order to find the best discriminative method. This is a time-consuming process that normally depends on intricate statistical tools. Results geneCommittee is a web-based interactive tool for routinely evaluating the discriminative classification power of custom hypothesis in the form of biologically relevant gene sets. While the user can work with different gene set collections and several microarray data files to configure specific classification experiments, the tool is able to run several tests in parallel. Provided with a straightforward and intuitive interface, geneCommittee is able to render valuable information for diagnostic analyses and clinical management decisions based on systematically evaluating custom hypothesis over different data sets using complementary classifiers, a key aspect in clinical research. Conclusions geneCommittee allows the enrichment of microarrays raw data with gene functional annotations, producing integrated datasets that simplify the construction of better discriminative hypothesis, and allows the creation of a set of complementary classifiers. The trained committees can then be used for clinical research and diagnosis. Full documentation including common use cases and guided analysis workflows is freely available at http://sing.ei.uvigo.es/GC/. PMID:24475928

  11. Rungs 1 to 4 of DFT Jacob's ladder: Extensive test on the lattice constant, bulk modulus, and cohesive energy of solids

    NASA Astrophysics Data System (ADS)

    Tran, Fabien; Stelzl, Julia; Blaha, Peter

    2016-05-01

    A large panel of old and recently proposed exchange-correlation functionals belonging to rungs 1 to 4 of Jacob's ladder of density functional theory are tested (with and without a dispersion correction term) for the calculation of the lattice constant, bulk modulus, and cohesive energy of solids. Particular attention will be paid to the functionals MGGA_MS2 [J. Sun et al., J. Chem. Phys. 138, 044113 (2013)], mBEEF [J. Wellendorff et al., J. Chem. Phys. 140, 144107 (2014)], and SCAN [J. Sun et al., Phys. Rev. Lett. 115, 036402 (2015)] which are meta-generalized gradient approximations (meta-GGA) and are developed with the goal to be universally good. Another goal is also to determine for which semilocal functionals and groups of solids it is beneficial (or not necessary) to use the Hartree-Fock exchange or a dispersion correction term. It is concluded that for strongly bound solids, functionals of the GGA, i.e., rung 2 of Jacob's ladder, are as accurate as the more sophisticated functionals of the higher rungs, while it is necessary to use dispersion corrected functionals in order to expect at least meaningful results for weakly bound solids. If results for finite systems are also considered, then the meta-GGA functionals are overall clearly superior to the GGA functionals.

  12. Preschool Psychopathology Reported by Parents in 23 Societies: Testing the Seven-Syndrome Model of the Child Behavior Checklist for Ages 1.5-5

    ERIC Educational Resources Information Center

    Ivanova, Masha Y.; Achenbach, Thomas M.; Rescorla, Leslie A.; Harder, Valerie S.; Ang, Rebecca P.; Bilenberg, Niels; Bjarnadottir, Gudrun; Capron, Christiane; De Pauw, Sarah S. W.; Dias, Pedro; Dobrean, Anca; Doepfner, Manfred; Duyme, Michele; Eapen, Valsamma; Erol, Nese; Esmaeili, Elaheh Mohammad; Ezpeleta, Lourdes; Frigerio, Alessandra; Goncalves, Miguel M.; Gudmundsson, Halldor S.; Jeng, Suh-Fang; Jetishi, Pranvera; Jusiene, Roma; Kim, Young-Ah; Kristensen, Solvejg; Lecannelier, Felipe; Leung, Patrick W. L.; Liu, Jianghong; Montirosso, Rosario; Oh, Kyung Ja; Plueck, Julia; Pomalima, Rolando; Shahini, Mimoza; Silva, Jaime R.; Simsek, Zynep; Sourander, Andre; Valverde, Jose; Van Leeuwen, Karla G.; Woo, Bernardine S. C.; Wu, Yen-Tzu; Zubrick, Stephen R.; Verhulst, Frank C.

    2010-01-01

    Objective: To test the fit of a seven-syndrome model to ratings of preschoolers' problems by parents in very diverse societies. Method: Parents of 19,106 children 18 to 71 months of age from 23 societies in Asia, Australasia, Europe, the Middle East, and South America completed the Child Behavior Checklist for Ages 1.5-5 (CBCL/1.5-5). Confirmatory…

  13. Development and evaluation of a self-administered on-line test of memory and attention for middle-aged and older adults

    PubMed Central

    Troyer, Angela K.; Rowe, Gillian; Murphy, Kelly J.; Levine, Brian; Leach, Larry; Hasher, Lynn

    2014-01-01

    There is a need for rapid and reliable Internet-based screening tools for cognitive assessment in middle-aged and older adults. We report the psychometric properties of an on-line tool designed to screen for cognitive deficits that require further investigation. The tool is composed of measures of memory and executive attention processes known to be sensitive to brain changes associated with aging and with cognitive disorders that become more prevalent with age. Measures included a Spatial Working Memory task, Stroop Interference task, Face-Name Association task, and Number-Letter Alternation task. Normative data were collected from 361 healthy adults age 50–79 who scored in the normal range on a standardized measure of general cognitive ability. Participants took the 20-minute on-line test on their home computers, and a subset of 288 participants repeated the test 1 week later. Analyses of the individual tasks indicated adequate internal consistency, construct validity, test-retest reliability, and alternate version reliability. As expected, scores were correlated with age. The four tasks loaded on the same principle component. Demographically-corrected z-scores from the individual tasks were combined to create an overall score, which showed good reliability and classification consistency. These results indicate the tool may be useful for identifying middle-aged and older adults with lower than expected scores who may benefit from clinical evaluation of their cognition by a health care professional. PMID:25540620

  14. A multi-case report of the pathways to and through genetic testing and cancer risk management for BRCA mutation-positive women aged 18-25.

    PubMed

    Hoskins, Lindsey M; Werner-Lin, Allison

    2013-02-01

    Much of the extant literature addressing the psychosocial aspects of BRCA1/2 mutation testing and risk management aggregates mutation carriers of all ages in study recruitment, data analysis, and interpretation. This analytic strategy does not adequately address the needs of the youngest genetic testing consumers, i.e., women aged 18-25. Despite low absolute cancer risk estimates before age 30, BRCA1/2 mutation-positive women aged 18-25 feel vulnerable to a cancer diagnosis but find themselves in a management quandary because the clinical utility of screening and prevention options are not yet well defined for such young carriers. We present three cases, selected from a larger study of 32 BRCA1/2 mutation-positive women who completed or considered genetic testing before age 25, to demonstrate the unique developmental, relational and temporal influences, as well as the challenges, experienced by very young BRCA mutation-positive women as they complete genetic testing and initiate cancer risk management. The first case describes the maturation of a young woman whose family participated in a national cancer registry. The second addresses the experiences and expectations of a young woman who completed genetic testing after learning that her unaffected father was a mutation carrier. The third case highlights the experiences of a young woman parentally bereaved in childhood, who presented for genetic counseling and testing due to intense family pressure. Together, these cases suggest that BRCA1/2-positive women aged 18-25 are challenged to reconcile their burgeoning independence from their families with risk-related support needs. Loved ones acting in ways meant to care for these young women may inadvertently apply pressure, convoluting family support dynamics and autonomous decision-making. Ongoing support from competent healthcare professionals will enable these young women to remain informed and receive objective counsel about their risk-management decisions. PMID

  15. Vacuuming with my mouth?: Children's ability to comprehend novel extensions of familiar verbs

    PubMed Central

    Seston, Rebecca; Golinkoff, Roberta Michnick; Ma, Weiyi; Hirsh-Pasek, Kathy

    2009-01-01

    Can 6- and 8-year-olds (and adults) comprehend common instrument verbs when extended to novel situations? Participants heard eight unusual extensions of common verbs and were asked to paraphrase the verbs' meanings. Half of the verbs used were specified instrument verbs that include the name of the instrument used to perform the action (e.g., a vacuum is used to vacuum); the other half were open instrument verbs (e.g., write) whose function can be performed with a range of objects. Results suggest that children's ability to interpret verb extensions increases with age, that open instrument verb extensions were more difficult to comprehend than specified instrument verb extensions and that performance on verb extension correlates with scores on a standardized test of language acquisition. Verb knowledge continues to develop well beyond the preschool years. PMID:20161104

  16. University of Wisconsin - Extension

    MedlinePlus

    ... Continuing and Online Education About Degree Programs Independent Learning School for Workers UW HELP UW System eCampus Cooperative Extension About Agriculture & Natural Resources Community, Natural Resource & ...

  17. Type Safe Extensible Programming

    NASA Astrophysics Data System (ADS)

    Chae, Wonseok

    2009-10-01

    Software products evolve over time. Sometimes they evolve by adding new features, and sometimes by either fixing bugs or replacing outdated implementations with new ones. When software engineers fail to anticipate such evolution during development, they will eventually be forced to re-architect or re-build from scratch. Therefore, it has been common practice to prepare for changes so that software products are extensible over their lifetimes. However, making software extensible is challenging because it is difficult to anticipate successive changes and to provide adequate abstraction mechanisms over potential changes. Such extensibility mechanisms, furthermore, should not compromise any existing functionality during extension. Software engineers would benefit from a tool that provides a way to add extensions in a reliable way. It is natural to expect programming languages to serve this role. Extensible programming is one effort to address these issues. In this thesis, we present type safe extensible programming using the MLPolyR language. MLPolyR is an ML-like functional language whose type system provides type-safe extensibility mechanisms at several levels. After presenting the language, we will show how these extensibility mechanisms can be put to good use in the context of product line engineering. Product line engineering is an emerging software engineering paradigm that aims to manage variations, which originate from successive changes in software.

  18. The influence of natural organic matter and aging on suspension stability in guideline toxicity testing of silver, zinc oxide, and titanium dioxide nanoparticles with Daphnia magna.

    PubMed

    Cupi, Denisa; Hartmann, Nanna B; Baun, Anders

    2015-03-01

    The present study investigated changes in suspension stability and ecotoxicity of engineered nanoparticles (ENPs) by addition of Suwannee River natural organic matter and aging of stock and test suspensions prior to testing. Acute toxicity tests of silver (Ag), zinc oxide (ZnO), and titanium dioxide (TiO2 ) ENPs with Daphnia magna were carried out following Organisation for Economic Co-operation and Development test guidelines. Daphnia magna was found to be very sensitive to Ag ENPs (48-h 50% effective concentration 33 μg L(-1) ), and aging of the test suspensions in M7 medium (up to 48 h) did not decrease toxicity significantly. Conversely, the presence of Suwannee River natural organic matter (NOM; 20 mg L(-1) ) completely alleviated Ag ENP toxicity in all testing scenarios and did not aid in stabilizing suspensions. In contrast, addition of Suwannee River NOM stabilized ZnO ENP suspensions and did not decrease toxicity. Aging for 48 h generated monotonous concentration-response curves in the presence and absence of Suwannee River NOM. At concentrations up to 100 mg L(-1) TiO2 ENPs did not cause immobilization of D. magna under any of the tested conditions. Presence of Suwannee River NOM caused agglomeration in stock suspensions. The authors' results suggest that aging and presence of Suwannee River NOM are important parameters in standard toxicity testing of ENPs, which in some cases may aid in gaining better control over the exposure conditions but in other cases might contribute to agglomeration or elimination of ENP toxicity. Therefore, modifications to the current guidelines for testing ENPs should be evaluated on a case-by-case basis. Environ Toxicol Chem 2015;34:497-506. © 2014 SETAC. PMID:25546145

  19. Determination of the availability of appropriate aged flight rocket motors. [captive tests to determine case bond separation and grain bore cracking

    NASA Technical Reports Server (NTRS)

    Martin, P. J.

    1974-01-01

    A program to identify surplus solid rocket propellant engines which would be available for a program of functional integrity testing was conducted. The engines are classified as: (1) upper stage and apogee engines, (2) sounding rocket and launch vehicle engines, and (3) jato, sled, and tactical engines. Nearly all the engines were available because their age exceeds the warranted shelf life. The preference for testing included tests at nominal flight conditions, at design limits, and to establish margin limits. The principal failure modes of interest were case bond separation and grain bore cracking. Data concerning the identification and characteristics of each engine are tabulated. Methods for conducting the tests are described.

  20. Assessment of the phytotoxicity of seaport sediments in the framework of a quarry-deposit scenario: germination tests of sediments aged artificially by column leaching.

    PubMed

    Bedell, J-P; Bazin, C; Sarrazin, B; Perrodin, Y

    2013-07-01

    The aim of the Sustainable Management of Sediments Dredged in Seaports (SEDIGEST) project is to assess the risks of treated port sediments for terrestrial ecosystems when deposited in quarries. We simulated the "ageing" of these sediments up to the "moment" when plants can germinate. Sediments were leached by water percolating through a laboratory column. Sediments 1 and 2, taken from the port of Toulon (France), were dried and aired. Sediment 3, taken from the port of Guilvinec (France), was stabilised with lime. Phytotoxicity was evaluated on the three artificially aged sediments using germination and early development tests (48 h to 7 days) by Phytotoxkit F(TM) bioassays. The three dilutions tested were performed with the reference "ISO substrate" and with Lolium perenne sp. (rye grass), Sinapis alba (white mustard), and Lepidium sativum (watercress). The tests performed with sediments 1 and 2 showed (1) a decrease of their toxicity to the germination of the species selected following leaching and (2) that L. perenne was the most sensitive species. The tests performed with sediment 3 showed that it was improper for colonisation even after leaching simulating 16 months of ageing. These germination tests on aged sediments identified the effects of leaching and made it possible to appreciate the capacity of the sediments to allow colonisation by plants. PMID:23456254

  1. Testing.

    ERIC Educational Resources Information Center

    Killoran, James, Ed.

    1984-01-01

    This journal issue addresses the issue of testing in the social studies classroom. The first article, "The Role of Testing" (Bragaw), focuses on the need for tests to reflect the objectives of the study completed. The varying functions of pop quizzes, weekly tests, and unit tests are explored. "Testing Thinking Processes" (Killoran, Zimmer, and…

  2. Aging and Strategic Retrieval in a Cued-Recall Test: The Role of Executive Functions and Fluid Intelligence

    ERIC Educational Resources Information Center

    Taconnat, Laurence; Clarys, David; Vanneste, Sandrine; Bouazzaoui, Badiaa; Isingrini, Michel

    2007-01-01

    Cued-recall in episodic memory was investigated in relation to low and high cognitive support at retrieval, executive function level and fluid intelligence level in 81 healthy adults divided first into two age groups (young and elderly adults). The first analyses showed that age-related differences were greater when a low cognitive support was…

  3. Approach for Service Life Extension of Explosive Devices for Aircraft Escape Systems

    NASA Technical Reports Server (NTRS)

    Bement, L. J.; Schimmel, M. L.

    1985-01-01

    The service life evaluation of explosive devices used in a wide variety of aircraft escape systems is described. The purpose was to develop a service extension approach, supported by tests on candidate devices, to evaluate the effects of service, age, and degradation, and allow responsible, conservative, service life determinations. An overview is given on the recommended approach and experimental procedures for accurate service evaluations with test results on rigid and flexible explosive transfer lines, one-way transfers, and flexible linear shaped charges.

  4. An experimental test for age-related improvements in reproductive performance in a frog that cares for its young

    NASA Astrophysics Data System (ADS)

    Dugas, Matthew B.; Moore, Michael P.; Wamelink, Caitlin N.; Richards-Zawacki, Corinne L.; Martin, Ryan A.

    2015-10-01

    Reproductive performance often increases with age in long-lived iteroparous organisms, a pattern that can result from within-individual increases in effort and/or competence. In free-living populations, it is typically difficult to distinguish these mechanisms or to isolate particular features of reproduction-influencing outcomes. In captive Oophaga pumilio, a frog in which mothers provide extended offspring provisioning via trophic eggs, we experimentally manipulated the age at which females started breeding and then monitored them across repeated reproductive events. This experiment allowed us to decouple age and experience and isolate maternal care as the proximate source of any differences in performance. Younger first-time mothers produced larger broods than older first-time mothers, but did not rear more offspring to independence. Across repeated reproductive events, maternal age was unassociated with any metric of performance. At later reproductive events, however, mothers produced fewer metamorphs, and a lower proportion of individuals in their broods reached independence. These patterns suggest that performance does not improve with age or breeding experience in this frog, and that eventual declines in performance are driven by reproductive activity, not age per se. Broadly, age-specific patterns of reproductive performance may depend on the proximate mechanism by which parents influence offspring fitness and how sensitive these are to effort and competence.

  5. The CAHPER Fitness-Performance Test Manual: For Boys and Girls 7 to 17 Years of Age.

    ERIC Educational Resources Information Center

    Canadian Association for Health, Physical Education, and Recreation, Ottawa (Ontario).

    Outlined in this manual is Canada's first National Test of Physical Fitness. Each test item is a valid and reliable measure of fitness, simple enough for any teacher not trained in fitness measurement to administer. Each of the six tests measures a different aspect of fitness: (1) the one-minute speed sit-up tests the strength and endurance of the…

  6. Assessing Growth in Young Children: A Comparison of Raw, Age-Equivalent, and Standard Scores Using the Peabody Picture Vocabulary Test

    ERIC Educational Resources Information Center

    Sullivan, Jeremy R.; Winter, Suzanne M.; Sass, Daniel A.; Svenkerud, Nicole

    2014-01-01

    Many tests provide users with several different types of scores to facilitate interpretation and description of students' performance. Common examples include raw scores, age- and grade-equivalent scores, and standard scores. However, when used within the context of assessing growth among young children, these scores should not be…

  7. 16 CFR Figure 4 to Part 1203 - Location of Test Lines for Helmets Intended for Persons Five (5) Years of Age and Older

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Location of Test Lines for Helmets Intended for Persons Five (5) Years of Age and Older 4 Figure 4 to Part 1203 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR BICYCLE HELMETS...

  8. 16 CFR Figure 4 to Part 1203 - Location of Test Lines for Helmets Intended for Persons Five (5) Years of Age and Older

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Location of Test Lines for Helmets Intended for Persons Five (5) Years of Age and Older 4 Figure 4 to Part 1203 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR BICYCLE HELMETS...

  9. 16 CFR Figure 4 to Part 1203 - Location of Test Lines for Helmets Intended for Persons Five (5) Years of Age and Older

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 2 2013-01-01 2013-01-01 false Location of Test Lines for Helmets Intended for Persons Five (5) Years of Age and Older 4 Figure 4 to Part 1203 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR BICYCLE HELMETS...

  10. 16 CFR Figure 4 to Part 1203 - Location of Test Lines for Helmets Intended for Persons Five (5) Years of Age and Older

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Location of Test Lines for Helmets Intended for Persons Five (5) Years of Age and Older 4 Figure 4 to Part 1203 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR BICYCLE HELMETS...

  11. A Pilot Evaluation of the Test-Retest Score Reliability of the Dimensions of Mastery Questionnaire in Preschool-Aged Children

    ERIC Educational Resources Information Center

    Igoe, Deirdre; Peralta, Christopher; Jean, Lindsey; Vo, Sandra; Yep, Linda Ngan; Zabjek, Karl; Wright, F. Virginia

    2011-01-01

    Preschool-aged children continually learn new skills and perfect existing ones. "Mastery motivation" is theorized to be a personality trait linked to skill learning. The Dimensions of Mastery Questionnaire (DMQ) quantifies mastery motivation. This pilot study evaluated DMQ test-retest score reliability (preschool-version) and included exploratory…

  12. Electrochemical impedance spectroscopy for lithium-ion cells: Test equipment and procedures for aging and fast characterization in time and frequency domain

    NASA Astrophysics Data System (ADS)

    Lohmann, Nils; Weßkamp, Patrick; Haußmann, Peter; Melbert, Joachim; Musch, Thomas

    2015-01-01

    New test equipment and characterization methods for aging investigations on lithium-ion cells for automotive applications are presented in this work. Electrochemical impedance spectroscopy (EIS) is a well-established method for cell characterization and analyzing electrochemical processes. In order to integrate this method into long-term aging studies with real driving currents, new test equipment is mandatory. The presented test equipment meets the demands for high current, wide bandwidth and precise measurement. This allows the cells to be cycled and characterized without interruption for changing the test device. The characterization procedures must be of short duration and have a minimum charge-throughput for negligible influence on the aging effect. This work presents new methods in the time and the frequency domain for obtaining the impedance spectrum which allow a flexible trade-off between measurement performance, time consumption and charge-throughput. In addition to sinusoidal waveforms, rectangular, Gaussian and sin(x)/x pulses are applied for EIS. The performance of the different methods is discussed. Finally, the time domain analysis is applied with real driving currents which provides impedance spectra for state of charge estimation considering aging effects in the car.

  13. Age-Related Differences and Cognitive Correlates of Self-Reported and Direct Navigation Performance: The Effect of Real and Virtual Test Conditions Manipulation

    PubMed Central

    Taillade, Mathieu; N'Kaoua, Bernard; Sauzéon, Hélène

    2016-01-01

    The present study investigated the effect of aging on direct navigation measures and self-reported ones according to the real-virtual test manipulation. Navigation (wayfinding tasks) and spatial memory (paper-pencil tasks) performances, obtained either in real-world or in virtual-laboratory test conditions, were compared between young (n = 32) and older (n = 32) adults who had self-rated their everyday navigation behavior (SBSOD scale). Real age-related differences were observed in navigation tasks as well as in paper-pencil tasks, which investigated spatial learning relative to the distinction between survey-route knowledge. The manipulation of test conditions (real vs. virtual) did not change these age-related differences, which are mostly explained by age-related decline in both spatial abilities and executive functioning (measured with neuropsychological tests). In contrast, elderly adults did not differ from young adults in their self-reporting relative to everyday navigation, suggesting some underestimation of navigation difficulties by elderly adults. Also, spatial abilities in young participants had a mediating effect on the relations between actual and self-reported navigation performance, but not for older participants. So, it is assumed that the older adults carried out the navigation task with fewer available spatial abilities compared to young adults, resulting in inaccurate self-estimates. PMID:26834666

  14. HIV Testing in the Past Year among the U.S. Household Population Aged 15-44: 2011-2013. NCHS Data Brief. Number 202

    ERIC Educational Resources Information Center

    Copen, Casey E.; Chandra, Anjani; Febo-Vazquez, Isaedmarie

    2015-01-01

    In 2011, more than 1 million Americans aged 13 and over were living with HIV infection, and one in seven did not know their infection status. Routine, voluntary HIV testing is a recognized way to reduce HIV transmission. Using data from the 2011-2013 National Survey of Family Growth (NSFG), this report updates nationally representative estimates…

  15. Age-Differences in Environment Route Learning: The Role of Input and Recall-Test Modalities in Young and Older Adults

    ERIC Educational Resources Information Center

    Meneghetti, Chiara; Borella, Erika; Gyselinck, Valerie; De Beni, Rossana

    2012-01-01

    The aim of this research was to examine age-related differences in young and older adults in route learning, using different types of learning and recall test modalities. A sample of young adults (20-30 years old) and older adults (60-70 years old) learned a city route by using either a map or a description; they then performed a verification…

  16. A Confirmatory Factor Analysis of Cattell-Horn-Carroll Theory and Cross-Age Invariance of the Woodcock-Johnson Tests of Cognitive Abilities III

    ERIC Educational Resources Information Center

    Taub, Gordon E.; McGrew, Kevin S.

    2004-01-01

    Establishing an instrument's factorial invariance provides the empirical foundation to compare an individual's score across time or to examine the pattern of correlations between variables in differentiated age groups. In the recently published Woodcock-Johnson Tests of Cognitive Ability (WJ COG) and Achievement (WJ ACH) Third Edition (III) the…

  17. Sex Differences in Latent Cognitive Abilities Ages 6 to 59: Evidence from the Woodcock-Johnson III Tests of Cognitive Abilities

    ERIC Educational Resources Information Center

    Keith, Timothy Z.; Reynolds, Matthew R.; Patel, Puja G.; Ridley, Kristen P.

    2008-01-01

    Sex differences in the latent general and broad cognitive abilities underlying the Woodcock-Johnson Tests of Cognitive Abilities were investigated for children, youth, and adults ages 6 through 59. A developmental, multiple indicator-multiple cause, structural equation model was used to investigate sex differences in latent cognitive abilities as…

  18. 16 CFR Figure 4 to Part 1203 - Location of Test Lines for Helmets Intended for Persons Five (5) Years of Age and Older

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Location of Test Lines for Helmets Intended for Persons Five (5) Years of Age and Older 4 Figure 4 to Part 1203 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS SAFETY STANDARD FOR BICYCLE HELMETS...

  19. The Level of Creative Abilities Dimensions According to Torrance Formal Test (B) and Their Relationship with Some Variables (Sex, Age, GPA)

    ERIC Educational Resources Information Center

    Awamleh, Habis; Al Farah, Yacoub; El-Zraigat, Ibrahim

    2012-01-01

    This study aimed to identify the level of dimensions for creative abilities (originality, flexibility, originality, elaboration) among students in Al Rai Jordanian schools according to Torrance Formal test, and to investigate the differences in these levels attributable to the study variables (gender, age, grade point average "GPA"). The…

  20. Examining age-related shared variance between face cognition, vision, and self-reported physical health: a test of the common cause hypothesis for social cognition

    PubMed Central

    Olderbak, Sally; Hildebrandt, Andrea; Wilhelm, Oliver

    2015-01-01

    The shared decline in cognitive abilities, sensory functions (e.g., vision and hearing), and physical health with increasing age is well documented with some research attributing this shared age-related decline to a single common cause (e.g., aging brain). We evaluate the extent to which the common cause hypothesis predicts associations between vision and physical health with social cognition abilities specifically face perception and face memory. Based on a sample of 443 adults (17–88 years old), we test a series of structural equation models, including Multiple Indicator Multiple Cause (MIMIC) models, and estimate the extent to which vision and self-reported physical health are related to face perception and face memory through a common factor, before and after controlling for their fluid cognitive component and the linear effects of age. Results suggest significant shared variance amongst these constructs, with a common factor explaining some, but not all, of the shared age-related variance. Also, we found that the relations of face perception, but not face memory, with vision and physical health could be completely explained by fluid cognition. Overall, results suggest that a single common cause explains most, but not all age-related shared variance with domain specific aging mechanisms evident. PMID:26321998

  1. Examining age-related shared variance between face cognition, vision, and self-reported physical health: a test of the common cause hypothesis for social cognition.

    PubMed

    Olderbak, Sally; Hildebrandt, Andrea; Wilhelm, Oliver

    2015-01-01

    The shared decline in cognitive abilities, sensory functions (e.g., vision and hearing), and physical health with increasing age is well documented with some research attributing this shared age-related decline to a single common cause (e.g., aging brain). We evaluate the extent to which the common cause hypothesis predicts associations between vision and physical health with social cognition abilities specifically face perception and face memory. Based on a sample of 443 adults (17-88 years old), we test a series of structural equation models, including Multiple Indicator Multiple Cause (MIMIC) models, and estimate the extent to which vision and self-reported physical health are related to face perception and face memory through a common factor, before and after controlling for their fluid cognitive component and the linear effects of age. Results suggest significant shared variance amongst these constructs, with a common factor explaining some, but not all, of the shared age-related variance. Also, we found that the relations of face perception, but not face memory, with vision and physical health could be completely explained by fluid cognition. Overall, results suggest that a single common cause explains most, but not all age-related shared variance with domain specific aging mechanisms evident. PMID:26321998

  2. Assessment of Simple Gait Related Dual and Triple Tests in Predicting the Risk of Fall in Adults Above Age of 50 years

    PubMed Central

    Chitalia, Disha

    2016-01-01

    Timed UP and Go Test (TUG) is conventionally used as predictor of falls in adults. Routine daily activities include multiple tasks performed concurrently. When two or more tasks (Dual/Triple test) needed to be carried out concurrently, task performance declined at least in one of them. Our study aimed to find temporal and demographic variations in the performance after adding a cognitive, motor or both tasks, while performing TUG, compared to performance during conventional TUG. Sixty randomly selected healthy adults, with age ranging from 53 to 90 years, consented to participate in the study. Each participant underwent six tests (Conventional TUG, Motor TUG, Cognitive TUG, Motor and Cognitive TUG, Visuospatial TUG, Motor and Visuospatial TUG), with time measured in seconds. 6 (10%) had a previous history of fall. Triple test identified the highest number of participants at risk of fall (16.67%). ​One way ANOVA test showed significant temporal variation with the addition of task (p value< 0.0002). There was moderate positive correlation of age with the time taken to perform each test with addition of task. Conventional TUG in itself was found to be most sensitive and specific test to identify fallers. Though dual and triple task tests were also comparable, addition of task to TUG is not a sensitive indicator to identify fallers as compared to TUG. PMID:27462477

  3. Assessment of Simple Gait Related Dual and Triple Tests in Predicting the Risk of Fall in Adults Above Age of 50 years.

    PubMed

    Paranjape, Swati; Chitalia, Disha

    2016-01-01

    Timed UP and Go Test (TUG) is conventionally used as predictor of falls in adults. Routine daily activities include multiple tasks performed concurrently. When two or more tasks (Dual/Triple test) needed to be carried out concurrently, task performance declined at least in one of them. Our study aimed to find temporal and demographic variations in the performance after adding a cognitive, motor or both tasks, while performing TUG, compared to performance during conventional TUG. Sixty randomly selected healthy adults, with age ranging from 53 to 90 years, consented to participate in the study. Each participant underwent six tests (Conventional TUG, Motor TUG, Cognitive TUG, Motor and Cognitive TUG, Visuospatial TUG, Motor and Visuospatial TUG), with time measured in seconds. 6 (10%) had a previous history of fall. Triple test identified the highest number of participants at risk of fall (16.67%). ​One way ANOVA test showed significant temporal variation with the addition of task (p value< 0.0002). There was moderate positive correlation of age with the time taken to perform each test with addition of task. Conventional TUG in itself was found to be most sensitive and specific test to identify fallers. Though dual and triple task tests were also comparable, addition of task to TUG is not a sensitive indicator to identify fallers as compared to TUG. PMID:27462477

  4. A computer-aided technique for testing cognitive functions. Validated on a sample of Danes 30 to 60 years of age.

    PubMed

    Laursen, P

    1990-01-01

    With the growing importance of occupational behavioural neurotoxicology the demand for a standardized and reliable cognitive test battery has become urgent. The present study deals with the compilation of a test battery, the purpose of which is to be sensitive to mild brain dysfunction and suitable for modern microcomputer administration and scoring. The battery comprises tests of learning and memory functions specific for each brain hemisphere (Face Recognition Test and Number Learning Test), visuomotor function separately for continuous and discrete tasks (Figure Drawing Test and Pen-to-Point Test), visuospatial function (Parallelogram Test), visual and auditive perception, attention and vigilance (Bourdon-Wiersma Test and Continuous Reaction-Time Test), and concentration (Continuous Graphics Test). The complete test battery was administered and scored on a slightly modified Tektronix 4052 computer with a Tektronix 4956 digitizer as a peripheral device. The validity of the battery was analysed on the basis of a sample of the normal Danish population (N = 1262) stratified for the ages 30, 40, 50, and 60 years, the two sexes, and residence in one of 11 municipalities in the western part of Copenhagen County. Using a 16-dimensional multivariate model comprising biological, social, psychological, and environmental factors, and also examiner behaviour, statistical analyses confirmed hypotheses of influence by the factors Age, Sex, Schooling, and Social Group, i.e. these factors partially explained the variance in the case of almost all the test parameters. Moreover, psychic stress, as determined in a questionnaire, had explanatory power with tests demanding attention and concentration. Hypotheses of effects on test performance by Smoking Status and psychophysiological diurnal or annual rhythms, i.e. Time of Day, and Time of Year, were confirmed for a few parameters, but the effects differed to some extent from those described in the literature. Alcohol Consumption

  5. Normal Values for the Full Visual Field, Corrected for Age- and Reaction Time, Using Semiautomated Kinetic Testing on the Octopus 900 Perimeter

    PubMed Central

    Grobbel, Julia; Dietzsch, Janko; Johnson, Chris A.; Vonthein, Reinhard; Stingl, Katarina; Weleber, Richard G.; Schiefer, Ulrich

    2016-01-01

    Purpose To determine normal values of the visual field (VF), corrected for age and reaction time (RT) for semiautomated kinetic perimetry (SKP) on the Octopus 900 perimeter, create a model describing the age-dependency of these values, and assess test–retest reliability for each isopter. Methods Eighty-six eyes of 86 ophthalmologically healthy subjects (age 11–79 years, 34 males, 52 females) underwent full-field kinetic perimetry with the Octopus 900 instrument. Stimulus size, luminance, velocity, meridional angle, subject age, and their interactions, were used to create a smooth multiple regression mathematical model (V/4e, III/4e, I/4e, I/3e, I/2e, I/1e, and I/1a isopters). Fourteen subjects (2 from each of 7 age groups) were evaluated on three separate sessions to assess test–retest reliability of the isopters. Reaction time (RT) was tested by presenting 12 designated RT-vectors between 10° and 20° within the seeing areas for the III/4e isopter (stimulus velocity, 3°/second). Four RT- vectors were presented at the nasal (0° or 180°), superotemporal (45°), and inferior (270°) meridians. Results The model fit was excellent (r2 = 0.94). The test–retest variability was less than 5°, and the median decrease in this deviation attributed to aging, per decade, for all age groups and for all stimulus sizes was 0.8°. No significant learning effect was observed for any age group or isopter. Conclusion Age-corrected and RT-corrected normative threshold values for full-field kinetic perimetry can be adequately described by a smooth multiple linear regression mathematical model. Translational Relevance A description of the entire kinetic VF is useful for assessing a full characterization of VF sensitivity, determining function losses associated with ocular and neurologic diseases, and for providing a more comprehensive analysis of structure–function relationships. PMID:26966641

  6. Age estimation by pulp/tooth area ratio in canines: study of a Portuguese sample to test Cameriere's method.

    PubMed

    Cameriere, R; Cunha, E; Sassaroli, E; Nuzzolese, E; Ferrante, L

    2009-12-15

    Age estimation in adults is an important problem in both anthropological and forensic fields, and apposition of secondary dentine is often used as an indicator of age. In recent papers, Cameriere et al. studied the pulp/tooth area ratio of canines for this purpose. The present study examines the application of the pulp/tooth area ratio by peri-apical X-ray images as an age indicator in a Portuguese identified sample. The statistical model was then compared with results from an Italian identified sample, to establish whether a common regression model for both samples could be developed. The Portuguese sample consisted of 126 canines of male and 132 of female from subjects 20 to 84 years old, from the osteological collection of the Museum of Anthropology at Coimbra University. The Italian sample consisted of 114 canines of male and 86 of female from subjects 20 to 79 years old, analyzed in Cameriere et al. (2007), and came from the Frassetto osteological collection of Sassari (Sardinia), now housed in the Museum of Anthropology, Department of Experimental and Evolutionistic Biology, University of Bologna. Statistical analysis was performed in order to obtain multiple regression formulas for dental age calculation, with chronological age as dependent variable, and gender and pulp/tooth area ratio on upper (RA(u)) and lower canines (RA(l)) as independent variables. ANCOVA analysis showed that gender was not significant but that variables RA(u) and RA(l) were. The regression model for the Portuguese sample yielded the following equations: Age=101.3-556.68 RA(u) (upper canines) and Age=92.37-492.05 RA(l) (lower canines). Both models explained about 97% of total variance, and mean prediction errors were ME=2.37 years and 2.55 years, respectively. Comparisons between the equation referring to the Portuguese sample and the equivalent linear equations proposed by Cameriere et al. for the Italian sample did not reveal significant differences between the linear models

  7. Toddler Developmental Delays After Extensive Hospitalization: Primary Care Practitioner Guidelines.

    PubMed

    Lehner, Dana C; Sadler, Lois S

    2015-01-01

    This review investigated developmental delays toddlers may encounter after a lengthy pediatric hospitalization (30 days or greater). Physical, motor, cognitive, and psychosocial development of children aged 1 to 3 years was reviewed to raise awareness of factors associated with developmental delay after extensive hospitalization. Findings from the literature suggest that neonatal and pediatric intensive care unit (NICU/PICU) graduates are most at risk for developmental delays, but even non-critical hospital stays interrupt development to some extent. Primary care practitioners (PCPs) may be able to minimize risk for delays through the use of formal developmental screening tests and parent report surveys. References and resources are described for developmental assessment to help clinicians recognize delays and to educate families about optimal toddler development interventions. Pediatric PCPs play a leading role in coordinating health and developmental services for the young child following an extensive hospital stay. PMID:26665423

  8. The utility of ancient human DNA for improving allele age estimates, with implications for demographic models and tests of natural selection

    PubMed Central

    Sams, Aaron J.; Hawks, John; Keinan, Alon

    2015-01-01

    The age of polymorphic alleles in humans is often estimated from population genetic patterns in extant human populations, such as allele frequencies, linkage disequilibrium, and rate of mutations. Ancient DNA can improve the accuracy of such estimates, as well as facilitate testing the validity of demographic models underlying many population genetic methods. Specifically, the presence of an allele in a genome derived from an ancient sample testifies that the allele is at least as old as that sample. In this study, we consider a common method for estimating allele age based on allele frequency as applied to variants from the US National Institutes of Health (NIH) Heart, Lung, and Blood Institute (NHLBI) Exome Sequencing Project. We view these estimates in the context of the presence or absence of each allele in the genomes of the 5300 year old Tyrolean Iceman, Ötzi, and of the 50,000 year old Altai Neandertal. Our results illuminate the accuracy of these estimates and their sensitivity to demographic events that were not included in the model underlying age estimation. Specifically, allele presence in the Iceman genome provides a good fit of allele age estimates to the expectation based on the age of that specimen. The equivalent based on the Neandertal genome leads to a poorer fit. This is likely due in part to the older age of the Neandertal and the older time of the split between modern humans and Neandertals, but also due to gene flow from Neandertals to modern humans not being considered in the underlying demographic model. Thus, the incorporation of ancient DNA can improve allele age estimation, demographic modeling, and tests of natural selection. Our results also point to the importance of considering a more diverse set of ancient samples for understanding the geographic and temporal range of individual alleles. PMID:25467111

  9. The utility of ancient human DNA for improving allele age estimates, with implications for demographic models and tests of natural selection.

    PubMed

    Sams, Aaron J; Hawks, John; Keinan, Alon

    2015-02-01

    The age of polymorphic alleles in humans is often estimated from population genetic patterns in extant human populations, such as allele frequencies, linkage disequilibrium, and rate of mutations. Ancient DNA can improve the accuracy of such estimates, as well as facilitate testing the validity of demographic models underlying many population genetic methods. Specifically, the presence of an allele in a genome derived from an ancient sample testifies that the allele is at least as old as that sample. In this study, we consider a common method for estimating allele age based on allele frequency as applied to variants from the US National Institutes of Health (NIH) Heart, Lung, and Blood Institute (NHLBI) Exome Sequencing Project. We view these estimates in the context of the presence or absence of each allele in the genomes of the 5300 year old Tyrolean Iceman, Ötzi, and of the 50,000 year old Altai Neandertal. Our results illuminate the accuracy of these estimates and their sensitivity to demographic events that were not included in the model underlying age estimation. Specifically, allele presence in the Iceman genome provides a good fit of allele age estimates to the expectation based on the age of that specimen. The equivalent based on the Neandertal genome leads to a poorer fit. This is likely due in part to the older age of the Neandertal and the older time of the split between modern humans and Neandertals, but also due to gene flow from Neandertals to modern humans not being considered in the underlying demographic model. Thus, the incorporation of ancient DNA can improve allele age estimation, demographic modeling, and tests of natural selection. Our results also point to the importance of considering a more diverse set of ancient samples for understanding the geographic and temporal range of individual alleles. PMID:25467111

  10. Age, Sex, and Handedness Differentially Contribute to Neurospatial Function on the Memory Island and Novel-Image Novel-Location Tests

    PubMed Central

    Piper, Brian J.; Acevedo, Summer F.; Edwards, Krystle R.; Curtiss, Alan B.; McGinnis, Gwendolyn J.; Raber, Jacob

    2011-01-01

    Memory Island and the Novel-Image Novel-Location are recently developed measures of spatial learning and recognition-memory modeled after the Morris water maze and the novel object-recognition tests. The goal of this study was to characterize how sex, age, and handedness contribute to Memory Island and Novel-Image Novel-Location performance. Volunteers (N=287, ages 6 to 67) from a local science museum completed four Memory Island trials containing a visible target and four trials containing a hidden target. A pronounced sex difference favoring males was noted in all measures of hidden trial performance. The total latency during the hidden trials among older-adults was longer than younger-adults or adolescents. Faster and more efficient performance by males was also identified during the visible trials, particularly among children. Adolescents and younger-adults outperformed children and older ages. Sinistrals had a lower cumulative distance to the target. Novel-Image Novel-Location behavior was examined in a separate sample (N=128, ages 6 to 86). Females had higher Novel-Image and Novel-Location scores than males. Novel-Image performance was independent of age while sinistrals had elevated Novel-Image scores relative to dextrals. Together, these findings identify how sex, age, and handedness uniquely contribute to performance on these tasks. PMID:21463643

  11. A STUDY OF COUNTY COMMISSIONERS' PRECEPTION OF THE NORTH CAROLINA COOPERATIVE EXTENSION SERVICE, NORTHEASTERN EXTENSION DISTRICT, NORTH CAROLINA.

    ERIC Educational Resources Information Center

    WHITE, ESTELLE EDWARDS

    AN INTERVIEW QUESTIONNAIRE WAS USED TO DISCOVER HOW 85 ELECTED COUNTY COMMISSIONERS IN THE NORTHEASTERN EXTENSION DISTRICT OF NORTH CAROLINA PERCEIVED THE COOPERATIVE EXTENSION SERVICE. THE EXTENT TO WHICH TENURE AS A COMMISSIONER, OCCUPATION, EDUCATION, AGE, AND INVOLVEMENT IN EXTENSION ACTIVITIES WERE ASSOCIATED WITH THE PERCEPTION OF…

  12. Treatment Outcomes of Patients With Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis According to Drug Susceptibility Testing to First- and Second-line Drugs: An Individual Patient Data Meta-analysis

    PubMed Central

    Bastos, Mayara L.; Hussain, Hamidah; Weyer, Karin; Garcia-Garcia, Lourdes; Leimane, Vaira; Leung, Chi Chiu; Narita, Masahiro; Penã, Jose M.; Ponce-de-Leon, Alfredo; Seung, Kwonjune J.; Shean, Karen; Sifuentes-Osornio, José; Van der Walt, Martie; Van der Werf, Tjip S.; Yew, Wing Wai; Menzies, Dick; Ahuja, S.; Ashkin, D.; Avendaño, M.; Banerjee, R.; Bauer, M.; Becerra, M.; Benedetti, A.; Burgos, M.; Centis, R.; Chan, E.D.; Chiang, C.Y.; Cobelens, F.; Cox, H.; D'Ambrosio, L.; de Lange, W.C.M.; DeRiemer, K.; Enarson, D.; Falzon, D.; Flanagan, K.; Flood, J.; Gandhi, N.; Garcia-Garcia, L.; Granich, R.M.; Hollm-Delgado, M.G.; Holtz, T.H.; Hopewell, P.; Iseman, M.; Jarlsberg, L.G.; Keshavjee, S.; Kim, H.R.; Koh, W.J.; Lancaster, J.; Lange, C.; Leimane, V.; Leung, C.C.; Li, J.; Menzies, D.; Migliori, G.B.; Mitnick, C.M.; Narita, M.; Nathanson, E.; Odendaal, R.; O'Riordan, P.; Pai, M.; Palmero, D.; Park, S.K.; Pasvol, G.; Pena, J.; Pérez-Guzmán, C.; Ponce-de-Leon, A.; Quelapio, M.I.D.; Quy, H.T.; Riekstina, V.; Robert, J.; Royce, S.; Salim, M.; Schaaf, H.S.; Seung, K.J.; Shah, L.; Shean, K.; Shim, T.S.; Shin, S.S.; Shiraishi, Y.; Sifuentes-Osornio, J.; Sotgiu, G.; Strand, M.J.; Sung, S.W.; Tabarsi, P.; Tupasi, T.E.; Vargas, M.H.; van Altena, R.; van der Walt, M.; van der Werf, T.S.; Viiklepp, P.; Westenhouse, J.; Yew, W.W.; Yim, J.J.

    2014-01-01

    Background. Individualized treatment for multidrug-resistant (MDR) tuberculosis and extensively drug-resistant (XDR) tuberculosis depends upon reliable and valid drug susceptibility testing (DST) for pyrazinamide, ethambutol, and second-line tuberculosis drugs. However, the reliability of these tests is uncertain, due to unresolved methodological issues. We estimated the association of DST results for pyrazinamide, ethambutol, and second-line drugs with treatment outcomes in patients with MDR tuberculosis and XDR tuberculosis. Methods. We conducted an analysis of individual patient data assembled from 31 previously published cohort studies of patients with MDR and XDR tuberculosis. We used data on patients' clinical characteristics including DST results, treatment received, outcomes, and laboratory methods in each center. Results. DST methods and treatment regimens used in different centers varied considerably. Among 8955 analyzed patients, in vitro susceptibility to individual drugs was consistently and significantly associated with higher odds of treatment success (compared with resistance to the drug), if that drug was used in the treatment regimen. Various adjusted and sensitivity analyses suggest that this was not explained by confounding. The adjusted odds of treatment success for ethambutol, pyrazinamide, and the group 4 drugs ranged from 1.7 to 2.3, whereas for second-line injectables and fluoroquinolones, odds ranged from 2.4 to 4.6. Conclusions. DST for ethambutol, pyrazinamide, and second-line tuberculosis drugs appears to provide clinically useful information to guide selection of treatment regimens for MDR and XDR tuberculosis. PMID:25097082

  13. Executive function is less sensitive to estradiol than spatial memory: performance on an analog of the card sorting test in ovariectomized aged rhesus monkeys.

    PubMed

    Lacreuse, A; Chhabra, R K; Hall, M J; Herndon, J G

    2004-09-30

    Functions supported by the frontal lobes are particularly sensitive to the detrimental effects of aging. Recent studies on postmenopausal women find that estrogen replacement therapy benefits performance on tasks dependent on the frontal lobes. To determine whether estrogen has a similar influence in a rhesus monkey model of menopause, we tested five aged, long-term ovariectomized rhesus monkeys in a modified version of the Wisconsin Card Sort test which had been adapted to the nonhuman primate. In this test, monkeys had to select 3-D objects based either on color (blue, red, yellow) or shape (block, tube, cup) and had to be able to switch their response as a function of reinforcement contingencies. The monkeys were treated with placebo and ethinyl estradiol (EE2, 450 ng/kg/day) in alternation with each successive test. Contrary to our hypothesis, estradiol treatment did not affect performance. Because previous studies in the same monkeys [Neurobiol. Aging 23 (2002) 589] had shown that EE2 improves performance on a spatial memory task dependent on the hippocampus, but not on another task dependent upon the frontal lobes (the delayed response), we conclude that executive processes may be less sensitive to the effects of estradiol than hippocampal-dependent tasks. PMID:15499681

  14. Transverse flexural tests as a tool for assessing damage to PMR-15 composites from isothermal aging in air at elevated temperatures

    NASA Technical Reports Server (NTRS)

    Bowles, Kenneth J.

    1992-01-01

    To date, the effect of thermo-oxidative aging on unidirectional composite mechanical properties has been monitored by the measurement of interlaminar shear strength (ILSS) and either three or four point longitudinal flexural strength (LFS) of the composites being tested. Both results are affected by the fiber-to-matrix bonding, the former being dependent on the shear resistance of the interface and the latter on the degree of load sharing by the fibers through the fiber/matrix interface. Recently, fiber/matrix interfacial bond strengths have been monitored using a transverse flexural strength (TFS) test method. This test method was used to evaluate the effect of fiber surface treatment on the fiber/matrix bond. The interface bonding was varied in these tests using Hercules A-fibers with three-types of surfaces that produce bonds of poor, better, and good quality. The TFS was found not only to be sensitive to the bonding, but also to the aging time of unidirectional A-fiber/PMR-15 composites. This relationship reflects the mechanism by which the PMR-15 degrades during thermal aging.

  15. Same-Age Unrelated Siblings: A Unique Test of Within-Family Environmental Influences on IQ Similarity.

    ERIC Educational Resources Information Center

    Segal, Nancy L.

    1997-01-01

    Pairs of genetically unrelated children reared as same-age siblings offer a design for investigating genetic and environmental influences on behavior. Results with 21 pairs support an explanatory model of intelligence that includes genetic factors. Shared environment appeared to have a very small effect on intellectual development. (SLD)

  16. The Development of Early Literacy Skills among Children with Speech Difficulties: A Test of the "Critical Age Hypothesis".

    ERIC Educational Resources Information Center

    Nathan, Liz; Stackhouse, Joy; Goulandris, Nata; Snowling, Margaret J.

    2004-01-01

    This article presents a longitudinal study of the early literacy development of 47 children with speech difficulties from ages 4 to 7 years. Of these children, 19 with specific speech difficulties were compared with 19 children with speech and language difficulties and 19 normally developing controls. The risk of literacy difficulties was greater…

  17. Age-related and intelligence-related differences in implicit memory: effects of generation on a word-fragment completion test.

    PubMed

    Komatsu, S; Naito, M; Fuke, T

    1996-07-01

    In two experiments, subjects either read a bracketed word in a sentence or generated a word in response to its definition. A word-fragment completion test was then carried out. In Experiment 1, children's priming under the generate condition was substantial, as compared with baseline performance, but was significantly lower than that under the read condition, whereas there was no difference in adults' priming between these two conditions. Furthermore, prior generation induced an age-related increase in priming despite no age difference under the read condition. In Experiment 2, mentally retarded persons exhibited a profile similar to that of children. These results suggests that there are two different components in implicit memory, one that shows no developmental difference and heavily relies on perceptual processing and the other that shows an age-related or intelligence-related increase and heavily relies on conceptual processing. PMID:8683186

  18. Point-Counterpoint: Cervical Cancer Screening Should Be Done by Primary Human Papillomavirus Testing with Genotyping and Reflex Cytology for Women over the Age of 25 Years.

    PubMed

    Stoler, Mark H; Austin, R Marshall; Zhao, Chengquan

    2015-09-01

    Screening for cervical cancer with cytology testing has been very effective in reducing cervical cancer in the United States. For decades, the approach was an annual Pap test. In 2000, the Hybrid Capture 2 human papillomavirus (HPV) test was approved by the U.S. Food and Drug Administration (FDA) for screening women who have atypical squamous cells of underdetermined significance (ASCUS) detected by Pap test to determine the need for colposcopy. In 2003, the FDA approved expanding the use of the test to include screening performed in conjunction with a Pap test for women over the age of 30 years, referred to as "cotesting." Cotesting allows women to extend the testing interval to 3 years if both tests have negative results. In April of 2014, the FDA approved the use of an HPV test (the cobas HPV test) for primary cervical cancer screening for women over the age of 25 years, without the need for a concomitant Pap test. The approval recommended either colposcopy or a Pap test for patients with specific high-risk HPV types detected by the HPV test. This was based on the results of the ATHENA trial, which included more than 40,000 women. Reaction to this decision has been mixed. Supporters point to the fact that the primary-screening algorithm found more disease (cervical intraepithelial neoplasia 3 or worse [CIN3+]) and also found it earlier than did cytology or cotesting. Moreover, the positive predictive value and positive-likelihood ratio of the primary-screening algorithm were higher than those of cytology. Opponents of the decision prefer cotesting, as this approach detects more disease than the HPV test alone. In addition, the performance of this new algorithm has not been assessed in routine clinical use. Professional organizations will need to develop guidelines that incorporate this testing algorithm. In this Point-Counterpoint, Dr. Stoler explains why he favors the primary-screening algorithm, while Drs. Austin and Zhao explain why they prefer the cotesting

  19. (U-Th)/He Apatite Age Data From the Inyo Mountains, California: Implications for the Timing of Extension and Dextral Slip Rates Along the Western Boundary of the Basin Range Province/Eastern California Shear Zone

    NASA Astrophysics Data System (ADS)

    Lee, J.; Stockli, D.

    2006-12-01

    With topographic relief of ~2.7 km, the Inyo Mountains, California is one of the largest mountains within the western part of the Basin Range Province (BRP) and Eastern California Shear Zone (ECSZ). This rugged range is underlain by Paleozoic sedimentary and metasedimentary rocks, Mesozoic plutons, and Quaternary alluvial deposits. An active, east-dipping normal fault, the eastern Inyo fault zone (EIFZ), defines the eastern flank of the range; the Saline Valley pull-apart basin is exposed in its hanging wall. To the south, the dextral Hunter Mountain fault (HMF) connects the EIFZ to the Panamint Valley fault. We completed the first (U-Th)/He apatite thermochronometric study on 24 samples collected from the Pat Keyes pluton across the range that bear on the timing of normal slip along the EIFZ and provide insight into the distribution of dextral shear across the ECSZ. Samples from the west-side of the range yield an elevation invariant (U-Th)/He age of 50.9±0.9 Ma. In contrast, samples from the east side of the range define two exhumed Partial Retention Zones (PRZ) and inflection points. From the top of the range ages systematically decrease from ~50 Ma at the top of the range to ~15 Ma. Below this upper inflection point, samples yield invariant (U-Th)/He ages of 15.0±0.3 Ma over a vertical distance of 0.8 km. (U-Th)/He ages then decrease again from ~15 Ma to ~3 Ma defining a Miocene-Pliocene PRZ. At the range front, below this lower inflection point, samples yield an invariant age of 2.8±0.1 Ma. We interpret these age patterns as indicating: (a) slow cooling (0.03- 0.06 mm/yr) through an older PRZ at high structural levels between >50 and 15.0 Ma; (b) rapid cooling, exhumation, and normal slip along the EIFZ at 15.0 Ma accommodated by westward tilting; (c) slow cooling (0.03-0.06 mm/yr) between 15.0 and 2.8 Ma through a younger PRZ; and (d) rapid cooling, exhumation, and renewed normal slip along the EIFZ at 2.8 Ma. The two episodes of exhumation along the EIFZ

  20. Applications and extensions of degradation modeling

    SciTech Connect

    Hsu, F.; Subudhi, M.; Samanta, P.K. ); Vesely, W.E. )

    1991-01-01

    Component degradation modeling being developed to understand the aging process can have many applications with potential advantages. Previous work has focused on developing the basic concepts and mathematical development of a simple degradation model. Using this simple model, times of degradations and failures occurrences were analyzed for standby components to detect indications of aging and to infer the effectiveness of maintenance in preventing age-related degradations from transforming to failures. Degradation modeling approaches can have broader applications in aging studies and in this paper, we discuss some of the extensions and applications of degradation modeling. The application and extension of degradation modeling approaches, presented in this paper, cover two aspects: (1) application to a continuously operating component, and (2) extension of the approach to analyze degradation-failure rate relationship. The application of the modeling approach to a continuously operating component (namely, air compressors) shows the usefulness of this approach in studying aging effects and the role of maintenance in this type component. In this case, aging effects in air compressors are demonstrated by the increase in both the degradation and failure rate and the faster increase in the failure rate compared to the degradation rate shows the ineffectiveness of the existing maintenance practices. Degradation-failure rate relationship was analyzed using data from residual heat removal system pumps. A simple linear model with a time-lag between these two parameters was studied. The application in this case showed a time-lag of 2 years for degradations to affect failure occurrences. 2 refs.

  1. Applications and extensions of degradation modeling

    SciTech Connect

    Hsu, F.; Subudhi, M.; Samanta, P.K.; Vesely, W.E.

    1991-12-31

    Component degradation modeling being developed to understand the aging process can have many applications with potential advantages. Previous work has focused on developing the basic concepts and mathematical development of a simple degradation model. Using this simple model, times of degradations and failures occurrences were analyzed for standby components to detect indications of aging and to infer the effectiveness of maintenance in preventing age-related degradations from transforming to failures. Degradation modeling approaches can have broader applications in aging studies and in this paper, we discuss some of the extensions and applications of degradation modeling. The application and extension of degradation modeling approaches, presented in this paper, cover two aspects: (1) application to a continuously operating component, and (2) extension of the approach to analyze degradation-failure rate relationship. The application of the modeling approach to a continuously operating component (namely, air compressors) shows the usefulness of this approach in studying aging effects and the role of maintenance in this type component. In this case, aging effects in air compressors are demonstrated by the increase in both the degradation and failure rate and the faster increase in the failure rate compared to the degradation rate shows the ineffectiveness of the existing maintenance practices. Degradation-failure rate relationship was analyzed using data from residual heat removal system pumps. A simple linear model with a time-lag between these two parameters was studied. The application in this case showed a time-lag of 2 years for degradations to affect failure occurrences. 2 refs.

  2. Testing the Critical Window Hypothesis of Timing and Duration of Estradiol Treatment on Hypothalamic Gene Networks in Reproductively Mature and Aging Female Rats

    PubMed Central

    Yin, Weiling; Maguire, Sean M.; Pham, Brian; Garcia, Alexandra N.; Dang, Nguyen-Vy; Liang, Jingya; Wolfe, Andrew; Hofmann, Hans A.

    2015-01-01

    At menopause, the dramatic loss of ovarian estradiol (E2) necessitates the adaptation of estrogen-sensitive neurons in the hypothalamus to an estrogen-depleted environment. We developed a rat model to test the “critical window” hypothesis of the effects of timing and duration of E2 treatment after deprivation on the hypothalamic neuronal gene network in the arcuate nucleus and the medial preoptic area. Rats at 2 ages (reproductively mature or aging) were ovariectomized and given E2 or vehicle replacement regimes of differing timing and duration. Using a 48-gene quantitative low-density PCR array and weighted gene coexpression network analysis, we identified gene modules differentially regulated by age, timing, and duration of E2 treatment. Of particular interest, E2 status differentially affected suites of genes in the hypothalamus involved in energy balance, circadian rhythms, and reproduction. In fact, E2 status was the dominant factor in determining gene modules and hormone levels; age, timing, and duration had more subtle effects. Our results highlight the plasticity of hypothalamic neuroendocrine systems during reproductive aging and its surprising ability to adapt to diverse E2 replacement regimes. PMID:26018250

  3. Shear and Pull Testing of Sn-3.0Ag-0.5Cu Solder with Ti/Ni(V)/Cu Underbump Metallization During Aging

    NASA Astrophysics Data System (ADS)

    Wang, Kai-Jheng; Duh, Jenq-Gong

    2009-12-01

    Ti/Ni(V)/Cu underbump metallization (UBM) is widely used in flip-chip technology today. The advantages of Ti/Ni(V)/Cu UBM are a low reaction rate with solder and the lack of a magnetic effect during sputtering. Sn atoms diffuse into the Ni(V) layer to form a Sn-rich phase, the so-called Sn-patch, during reflow and aging. In this study, the relationship between interfacial reaction and mechanical properties of the solder joints with Ti/Ni(V)/Cu UBM was evaluated. Sn-3.0Ag-0.5Cu solder was reflowed on sputtered Ti/Ni(V)/Cu UBM, and then the reflowed samples were aged at 125°C and 200°C, respectively. (Cu,Ni)6Sn5 was formed and grew gradually at the interface of the solder joints during aging at 125°C. The Sn-patch replaced the Ni(V) layer, and (Ni,Cu)3Sn4 was thus formed between (Cu,Ni)6Sn5 and the Sn-patch at 200°C. The Sn-patch, composed of Ni and V2Sn3 after reflow, was transformed to V2Sn3 and amorphous Sn during aging. Shear and pull tests were applied to evaluate the solder joints under various heat treatments. The shear force of the solder joints remained at 421 mN, yet the pull force decreased after aging at 125°C. Both the shear and pull forces of the solder joints decreased during aging at 200°C. The effects of aging temperature on the mechanical properties of solder joint were investigated and discussed.

  4. Mobile Applications for Extension

    ERIC Educational Resources Information Center

    Drill, Sabrina L.

    2012-01-01

    Mobile computing devices (smart phones, tablets, etc.) are rapidly becoming the dominant means of communication worldwide and are increasingly being used for scientific investigation. This technology can further our Extension mission by increasing our power for data collection, information dissemination, and informed decision-making. Mobile…

  5. Extensions of Natural Hamiltonians

    NASA Astrophysics Data System (ADS)

    Rastelli, G.

    2014-03-01

    Given an n-dimensional natural Hamiltonian L on a Riemannian or pseudo-Riemannian manifold, we call "extension" of L the n+1 dimensional Hamiltonian H = ½p2u + α(u)L + β(u) with new canonically conjugated coordinates (u,pu). For suitable L, the functions α and β can be chosen depending on any natural number m such that H admits an extra polynomial first integral in the momenta of degree m, explicitly determined in the form of the m-th power of a differential operator applied to a certain function of coordinates and momenta. In particular, if L is maximally superintegrable (MS) then H is MS also. Therefore, the extension procedure allows the creation of new superintegrable systems from old ones. For m=2, the extra first integral generated by the extension procedure determines a second-order symmetry operator of a Laplace-Beltrami quantization of H, modified by taking in account the curvature of the configuration manifold. The extension procedure can be applied to several Hamiltonian systems, including the three-body Calogero and Wolfes systems (without harmonic term), the Tremblay-Turbiner-Winternitz system and n-dimensional anisotropic harmonic oscillators. We propose here a short review of the known results of the theory and some previews of new ones.

  6. Job Enrichment in Extension.

    ERIC Educational Resources Information Center

    Fourman, Louis S.; Jones, Jo

    1997-01-01

    Interviews with 10 participants in Ohio State University's job enrichment program for midcareer extension agents found that 5 returned to their same jobs after the experience but only 2 felt challenged/renewed. Part-time participation while working made it difficult to balance responsibilities. More information and a structured orientation were…

  7. Identifying High Extension Communicators

    ERIC Educational Resources Information Center

    Lionberger, Herbert F.; Pope, LaVern

    1978-01-01

    Reports results of a survey of social science faculty at the University of Missouri-Columbia to find the extent to which they engaged in communicating information to the public through university extension, with implications for changes in the university rewards system. (MF)

  8. Vocabulary Extension through Poetry.

    ERIC Educational Resources Information Center

    Surajlal, K. C.

    1986-01-01

    Based on the notion that teaching vocabulary extension in isolation makes little impact on students, a three-part exercise, designed to develop students' vocabulary through poetry while providing meaningful enjoyment, uses the poem "The Hawk" by A. C. Benson. In the first class period, students are introduced to both the exercise and the poem and…

  9. Extensive Reading in Japanese

    ERIC Educational Resources Information Center

    Hitosugi, Claire Ikumi; Day, Richard R.

    2004-01-01

    This article discusses how we incorporated an extensive reading (ER) program into a second semester Japanese course at the University of Hawai'i using Japanese children's literature. After summarizing the ten principles of ER, we describe how we addressed six critical issues faced while introducing ER into the course. We also discuss the outcomes…

  10. Extending Extensive Reading

    ERIC Educational Resources Information Center

    Day, Richard R.

    2015-01-01

    The April 2015 issue of "Reading in a Foreign Language" featured a discussion forum on extensive reading (ER). Most of the authors, recognized authorities on ER, discussed their views of the principles of ER, particularly in establishing and conducting ER programs. The purpose of this discussion is to review developments in the practice…

  11. Health Care Use and HIV Testing of Males Aged 15-39 Years in Physicians' Offices - United States, 2009-2012.

    PubMed

    Ham, D Cal; Huang, Ya-Lin; Gvetadze, Roman; Peters, Philip J; Hoover, Karen W

    2016-01-01

    In 2014, 81% of new human immunodeficiency virus (HIV) infection diagnoses in the United States were in males, with the highest number of cases among those aged 20-29 years. Racial and ethnic minorities continue to be disproportionately affected by HIV; there are 13 new diagnoses each year per 100,000 white males, 94 per 100,000 black males, and 42 per 100,000 Hispanic males (1). Despite the recommendation by CDC for HIV testing of adults and adolescents (2), in 2014, only 36% of U.S. males aged ≥18 years reported ever having an HIV test (3), and in 2012, an estimated 15% of males living with HIV had undiagnosed HIV infection (4). To identify opportunities for HIV diagnosis in young males, CDC analyzed data from the 2009-2012 National Ambulatory Medical Care Survey (NAMCS) and U.S. Census data to estimate rates of health care use at U.S. physicians' offices and HIV testing at these encounters. During 2009-2012, white males visited physicians' offices more often (average annual rate of 1.6 visits per person) than black males (0.9 visits per person) and Hispanic males (0.8 visits per person). Overall, an HIV test was performed at 1.0% of visits made by young males to physicians' offices, with higher testing rates among black males (2.7%) and Hispanic males (1.4%), compared with white males (0.7%). Although higher proportions of black and Hispanic males received HIV testing at health care visits compared with white males, this benefit is likely attenuated by a lower rate of health care visits. Interventions to routinize HIV testing at U.S physicians' offices could be implemented to improve HIV testing coverage. PMID:27337096

  12. Environmental aging in polycrystalline-Si photovoltaic modules: comparison of chamber-based accelerated degradation studies with field-test data

    NASA Astrophysics Data System (ADS)

    Lai, T.; Biggie, R.; Brooks, A.; Potter, B. G.; Simmons-Potter, K.

    2015-09-01

    Lifecycle degradation testing of photovoltaic (PV) modules in accelerated-degradation chambers can enable the prediction both of PV performance lifetimes and of return-on-investment for installations of PV systems. With degradation results strongly dependent on chamber test parameters, the validity of such studies relative to fielded, installed PV systems must be determined. In the present work, accelerated aging of a 250 W polycrystalline silicon module is compared to real-time performance degradation in a similar polycrystalline-silicon, fielded, PV technology that has been operating since October 2013. Investigation of environmental aging effects are performed in a full-scale, industrial-standard environmental chamber equipped with single-sun irradiance capability providing illumination uniformity of 98% over a 2 x 1.6 m area. Time-dependent, photovoltaic performance (J-V) is evaluated over a recurring, compressed night-day cycle providing representative local daily solar insolation for the southwestern United States, followed by dark (night) cycling. This cycle is synchronized with thermal and humidity environmental variations that are designed to mimic, as closely as possible, test-yard conditions specific to a 12 month weather profile for a fielded system in Tucson, AZ. Results confirm the impact of environmental conditions on the module long-term performance. While the effects of temperature de-rating can be clearly seen in the data, removal of these effects enables the clear interpretation of module efficiency degradation with time and environmental exposure. With the temperature-dependent effect removed, the normalized efficiency is computed and compared to performance results from another panel of similar technology that has previously experienced identical climate changes in the test yard. Analysis of relative PV module efficiency degradation for the chamber-tested system shows good comparison to the field-tested system with ~2.5% degradation following

  13. Upper Stage Engine Composite Nozzle Extensions

    NASA Technical Reports Server (NTRS)

    Valentine, Peter G.; Allen, Lee R.; Gradl, Paul R.; Greene, Sandra E.; Sullivan, Brian J.; Weller, Leslie J.; Koenig, John R.; Cuneo, Jacques C.; Thompson, James; Brown, Aaron; Shigley, John K.; Dovey, Henry N.; Roberts, Robert K.

    2015-01-01

    Carbon-carbon (C-C) composite nozzle extensions are of interest for use on a variety of launch vehicle upper stage engines and in-space propulsion systems. The C-C nozzle extension technology and test capabilities being developed are intended to support National Aeronautics and Space Administration (NASA) and United States Air Force (USAF) requirements, as well as broader industry needs. Recent and on-going efforts at the Marshall Space Flight Center (MSFC) are aimed at both (a) further developing the technology and databases for nozzle extensions fabricated from specific CC materials, and (b) developing and demonstrating low-cost capabilities for testing composite nozzle extensions. At present, materials development work is concentrating on developing a database for lyocell-based C-C that can be used for upper stage engine nozzle extension design, modeling, and analysis efforts. Lyocell-based C-C behaves in a manner similar to rayon-based CC, but does not have the environmental issues associated with the use of rayon. Future work will also further investigate technology and database gaps and needs for more-established polyacrylonitrile- (PAN-) based C-C's. As a low-cost means of being able to rapidly test and screen nozzle extension materials and structures, MSFC has recently established and demonstrated a test rig at MSFC's Test Stand (TS) 115 for testing subscale nozzle extensions with 3.5-inch inside diameters at the attachment plane. Test durations of up to 120 seconds have been demonstrated using oxygen/hydrogen propellants. Other propellant combinations, including the use of hydrocarbon fuels, can be used if desired. Another test capability being developed will allow the testing of larger nozzle extensions (13.5- inch inside diameters at the attachment plane) in environments more similar to those of actual oxygen/hydrogen upper stage engines. Two C-C nozzle extensions (one lyocell-based, one PAN-based) have been fabricated for testing with the larger

  14. Using Audience Response Devices for Extension Programming

    ERIC Educational Resources Information Center

    de Koff, Jason P.

    2013-01-01

    Audience response devices (ARDs), or "clickers," have traditionally been used in the classroom to take attendance, provide testing of current knowledge and knowledge gain, and assist with review of course topics. The ARDs were used at a recent Extension conference, which provided an opportunity to test how well this tool worked. Though…

  15. Transverse flexural tests as a tool for assessing damage to PMR-15 composites from isothermal aging in air at elevated temperatures

    NASA Technical Reports Server (NTRS)

    Bowles, Kenneth J.

    1993-01-01

    To date, the effect of thermo-oxidative aging on unidirectional composite mechanical properties has been monitored by the measurement of interlaminar shear strength (ILSS) and either three or four point longitudinal flexural strength (LFS) of the composites being tested. Both results are affected by the fiber-to-matrix bonding, the former being dependent on the shear resistance of the interface and the latter on the degree of load sharing by the fibers through the fiber/matrix interface. Recently, fiber/matrix interfacial bond strengths have been monitored using a transverse flexural strength (TFS) test method. This test method was used to evaluate the effect of fiber surface treatment on the fiber/matrix.

  16. Plutonium aging

    SciTech Connect

    Olivas, J.D.

    1999-03-01

    The author describes the plutonium aging program at the Los Alamos National Laboratory. The aging of plutonium components in the US nuclear weapons stockpile has become a concern due to several events: the end of the cold war, the cessation of full scale underground nuclear testing as a result of the Comprehensive Test Ban Treaty (CTBT) and the closure of the Rocky Flats Plant--the site where the plutonium components were manufactured. As a result, service lifetimes for nuclear weapons have been lengthened. Dr. Olivas will present a brief primer on the metallurgy of plutonium, and will then describe the technical approach to ascertaining the long-term changes that may be attributable to self-radiation damage. Facilities and experimental techniques which are in use to study aging will be described. Some preliminary results will also be presented.

  17. The relation of autologous serum and plasma skin test results with urticarial activity score, sex and age in patients with chronic urticaria

    PubMed Central

    Aktar, Sirac; Akdeniz, Necmettin; Calka, Omer; Karadag, Ayse Serap

    2015-01-01

    Introduction Some previous studies reported autoimmunity as an etiologic factor in chronic urticaria (CU), but the results of some autoimmunity tests in these studies are conflicting. Aim To concretize whether there was any relation of autologous serum skin test (ASST) and autologous plasma skin test (APST) results with sex, age and urticarial activity score (UAS) in patients with CU. Material and methods Fifty patients with CU and twenty healthy subjects admitted to our dermatology clinic were included in the present study. The ASST and APST were applied to all individuals. Results The positiveness rates of ASST and APST were significantly higher in the patient group than controls (p = 0.027, p = 0.001, respectively). Among patients, the APST positiveness rate (72%) was significantly (p < 0.05) higher than ASST (46%). It was seen that 48% of patients with negative ASST results had positive APST. However, no patient with negative APST results had positive ASST. There were significant (p < 0.05) relations of the tests’ positiveness rates with sex and old age but with UAS. The diameter of the erythematous papule was remarkably (p < 0.05) larger in APST than ASST and also significantly (p < 0.05) larger in females compared to males in both tests (p < 0.05). It was positively increased with old age (p < 0.05). Conclusions We can suggest that APST is more sensitive than ASST in the assessment of autoimmunity in CU. A high positiveness rate of APST results may be attributed to high numbers of autoantibodies and coagulation factors present in plasma that might probably play a role in etiopathogenesis of CU. PMID:26161057

  18. Manitoba Physical Fitness Performance Test Manual and Fitness Objectives for Manitoba Youth 5-18 Years of Age.

    ERIC Educational Resources Information Center

    Manitoba Dept. of Education, Winnipeg.

    The physical fitness and lifestyle of Canadian school children has been deteriorating in recent years. The main objectives of physical education are directed toward the development of physical fitness and a positive lifestyle. This manual provides an opportunity for measuring the components of physical fitness. Physical fitness testing involves…

  19. Performance of School Age Reading Disabled Students on the Phonological Awareness Subtests of the Comprehensive Test of Phonological Processing (CTOPP)

    ERIC Educational Resources Information Center

    Marshall, Dorothy; Christo, Catherine; Davis, John

    2013-01-01

    This study examined the performance of reading disabled children on the two Phonological Awareness Subtests of the Comprehensive Test of Phonological Processing (CTOPP). Participants performed significantly different on these two subtests with a poorer performance on the Elision subtest than Blending Words. In addition, the two subtests were not…

  20. Creativity Lost: The Importance of Testing Higher-Level Executive Functions in School-Age Children and Adolescents

    ERIC Educational Resources Information Center

    Delis, Dean C.; Lansing, Amy; Houston, Wes S.; Wetter, Spencer; Han, S. Duke; Jacobson, Mark; Holdnack, James; Kramer, Joel

    2007-01-01

    In school settings, students are typically evaluated using group achievement tests, IQ scales, and college entrance exams that focus more on rote-verbal skills (e.g., vocabulary, mathematical facts) than on higher level executive functions (e.g., abstract thinking, problem solving). However, recent neuropsychological findings suggest that…