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Sample records for factors influencing milk

  1. Invited review: organic and conventionally produced milk-an evaluation of factors influencing milk composition.

    PubMed

    Schwendel, B H; Wester, T J; Morel, P C H; Tavendale, M H; Deadman, C; Shadbolt, N M; Otter, D E

    2015-02-01

    Consumer perception of organic cow milk is associated with the assumption that organic milk differs from conventionally produced milk. The value associated with this difference justifies the premium retail price for organic milk. It includes the perceptions that organic dairy farming is kinder to the environment, animals, and people; that organic milk products are produced without the use of antibiotics, added hormones, synthetic chemicals, and genetic modification; and that they may have potential benefits for human health. Controlled studies investigating whether differences exist between organic and conventionally produced milk have so far been largely equivocal due principally to the complexity of the research question and the number of factors that can influence milk composition. A main complication is that farming practices and their effects differ depending on country, region, year, and season between and within organic and conventional systems. Factors influencing milk composition (e.g., diet, breed, and stage of lactation) have been studied individually, whereas interactions between multiple factors have been largely ignored. Studies that fail to consider that factors other than the farming system (organic vs. conventional) could have caused or contributed to the reported differences in milk composition make it impossible to determine whether a system-related difference exists between organic and conventional milk. Milk fatty acid composition has been a central research area when comparing organic and conventional milk largely because the milk fatty acid profile responds rapidly and is very sensitive to changes in diet. Consequently, the effect of farming practices (high input vs. low input) rather than farming system (organic vs. conventional) determines milk fatty acid profile, and similar results are seen between low-input organic and low-input conventional milks. This confounds our ability to develop an analytical method to distinguish organic from

  2. Physiological mechanisms, behavioral and psychological factors influencing the transfer of milk from mothers to their young.

    PubMed

    Jonas, Wibke; Woodside, Barbara

    2016-01-01

    This article is part of a Special Issue "Parental Care".Producing milk to support the growth of their young is a central element of maternal care in mammals. In spite of the facts that ecological constraints influence nursing frequency, length of time until weaning and the composition of milk, there is considerable similarity in the anatomy and physiology of milk production and delivery across mammalian species. Here we provide an overview of cross species variation in nursing patterns and milk composition as well as the mechanisms underlying mammary gland development, milk production and letdown. Not all women breastfeed their infants, thus in later sections we review studies of factors that facilitate or impede the initiation and duration of breastfeeding. The results of these investigations suggest that the decisions to initiate and maintain breastfeeding are influenced by an array of personal, social and biological factors. Finally, studies comparing the development of breastfed and formula fed infants as well as those investigating associations between breastfeeding, maternal health and mother/infant interaction are reviewed. Leading health agencies including the World Health Organization and CDC advocate breastfeeding for at least the first 6months postpartum. To achieve these rates will require not only institutional support but also a focus on individual mother/infant dyads and their experience. PMID:26232032

  3. Bioactive factors in milk across lactation: Maternal effects and influence on infant growth in rhesus macaques (Macaca mulatta).

    PubMed

    Bernstein, Robin M; Hinde, Katie

    2016-08-01

    Among mammals, numerous bioactive factors in milk vary across mothers and influence offspring outcomes. This emerging area of research has primarily investigated such dynamics within rodent biomedical models, domesticated dairy breeds, and among humans in clinical contexts. Less understood are signaling factors in the milk of non-human primates. Here, we report on multiple bioactive components in rhesus macaque (Macaca mulatta) milk and their associations with maternal and infant characteristics. Milk samples were collected from 59 macaques at multiple time points across lactation in conjunction with maternal and infant morphometrics and life-history animal records. Milk was assayed for adiponectin (APN), epidermal growth factor (EGF) and its receptor (EGF-R), and transforming growth factor beta 2 (TGF-β2 ). Regression models were constructed to assess the contributions of maternal factors on variation in milk bioactives, and on the relationship of this variation to infant body mass and growth. Maternal body mass, parity, social rank, and infant sex were all predictive of concentrations of milk bioactives. Primiparous mothers produced milk with higher adiponectin, but lower EGF, than multiparous mothers. Heavier mothers produced milk with lower EGF and EGF-R, but higher TGF-β2 . Mothers of daughters produced milk with higher TGF-β2 . Mid-ranking mothers produced milk with higher mean EGF and adiponectin concentrations than low-ranking mothers. Milk EGF and EGF-R were positively associated with infant body mass and growth rate. Importantly, these signaling bioactives (APN, EGF, EGF-R, and TGF-β2 ) were significantly correlated with nutritional values of milk. The effects of milk signals remained after controlling for the available energy in milk revealing the added physiological role of non-nutritive milk bioactives in the developing infant. Integrating analyses of energetic and other bioactive components of milk yields an important perspective for interpreting

  4. Lactobacilli and Bifidobacteria in Human Breast Milk: Influence of Antibiotherapy and Other Host and Clinical Factors

    PubMed Central

    Soto, Ana; Martín, Virginia; Jiménez, Esther; Mader, Isabelle; Rodríguez, Juan M.; Fernández, Leonides

    2014-01-01

    ABSTRACT Objective: The objective of this work was to study the lactobacilli and bifidobacteria population in human milk of healthy women, and to investigate the influence that several factors (including antibioteraphy during pregnancy and lactation, country and date of birth, delivery mode, or infant age) may exert on such population. Methods: A total of 160 women living in Germany or Austria provided the breast milk samples. Initially, 66 samples were randomly selected and cultured on MRS-Cys agar plates. Then, the presence of DNA from the genera Lactobacillus and Bifidobacterium, and from most of the Lactobacillus and Bifidobacterium species that were isolated, was assessed by qualitative polymerase chain reaction (PCR) using genus- and species-specific primers. Results: Lactobacilli and bifidobacteria could be isolated from the milk of 27 (40.91%) and 7 (10.61%), respectively, of the 66 cultured samples. On the contrary, Lactobacillus and Bifidobacterium sequences were detected by PCR in 108 (67.50%) and 41 (25.62%), respectively, of the 160 samples analyzed. The Lactobacillus species most frequently isolated and detected was L salivarius (35.00%), followed by L fermentum (25.00%) and L gasseri (21.88%), whereas B breve (13.75%) was the bifidobacterial species most commonly recovered and whose DNA was most regularly found. The number of lactobacilli- or bifidobacteria-positive samples was significantly lower in women who had received antibiotherapy during pregnancy or lactation. Conclusions: Our results suggest that either the presence of lactobacilli and/or bifidobacteria or their DNA may constitute good markers of a healthy human milk microbiota that has not been altered by the use of antibiotics. PMID:24590211

  5. Factors influencing degree of glycosylation and phosphorylation of caseins in individual cow milk samples.

    PubMed

    Poulsen, N A; Jensen, H B; Larsen, L B

    2016-05-01

    The aim of this study was to examine variations in posttranslational modifications (PTM) of caseins (CN) in milk from individual cows and determine how these differ between breeds, across lactation, and between variants. Furthermore, we examined the variation of casein PTM in relation to rennet coagulation properties of milk. In total, detailed protein composition of milk from 892 Danish Holstein and Jersey cows was determined by liquid chromatography/electrospray ionization-mass spectrometry. The method measured relative contents of the main milk proteins as well as several variants and PTM. The results showed that the 2 breeds had distinct milk protein composition. Milk from Danish Holstein cows was mainly characterized by higher relative contents of β-CN, α-lactalbumin (α-LA), and β-lactoglobulin, and a higher fraction of glycosylated κ-CN (G κ-CN), whereas milk from Danish Jersey cows was characterized by higher relative contents of κ-CN, αS2-CN, and the less phosphorylated forms of αS1-CN and αS2-CN. Univariate linear models including days in milk and parity as class effects showed variation in the detailed protein profile across and between lactations; in particular, changes in the degree of glycosylation of κ-CN were pronounced, but changes in αS1-CN 8P to total αS1-CN and αS2-CN 11P to αS2-CN were also observed over lactation for both breeds. The phosphorylated forms of αS1-CN and αS2-CN were, to some extent, correlated. Further, the κ-CN BB genotype was associated with higher relative contents of both unglycosylated κ-CN (UG κ-CN) and G κ-CN compared with κ-CN AA; κ-CN AB showed intermediate results in both breeds. The influence of protein composition on rennet coagulation properties was explored based on 4 classes for curd firming rate: noncoagulation, and poor, average, and good coagulation. The results revealed breed differences: Holstein milk, higher relative content of κ-CN to total protein, and higher content of G κ-CN were

  6. New approach to optimize near-infrared spectra with design of experiments and determination of milk compounds as influence factors for changing milk over time.

    PubMed

    De Benedictis, Lorenzo; Huck, Christian

    2016-12-01

    The optimization of near-infrared spectroscopic parameters was realized via design of experiments. With this new approach objectivity can be integrated into conventional, rather subjective approaches. The investigated factors are layer thickness, number of scans and temperature during measurement. Response variables in the full factorial design consisted of absorption intensity, signal-to-noise ratio and reproducibility of the spectra. Optimized factorial combinations have been found to be 0.5mm layer thickness, 64 scans and 25°C ambient temperature for liquid milk measurements. Qualitative analysis of milk indicated a strong correlation of environmental factors, as well as the feeding of cattle with respect to the change in milk composition. This was illustrated with the aid of near-infrared spectroscopy and the previously optimized parameters by detection of altered fatty acids in milk, especially by the fatty acid content (number of carboxylic functions) and the fatty acid length. PMID:27374567

  7. Verification of factors to estimate daily milk yield from one milking of cows milked twice daily

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The objective of this research was to verify factors to predict daily milk yield when milk is sampled once per d for cows milked twice (2x) per d. Milk weights for both milkings were recorded automatically by 30 herds and collected by Dairy Herd Improvement supervisors. Data was split into 2 subsets...

  8. Distribution of polychlorinated biphenyls and organochlorine pesticides in human breast milk from various locations in Tunisia: levels of contamination, influencing factors, and infant risk assessment.

    PubMed

    Ennaceur, S; Gandoura, N; Driss, M R

    2008-09-01

    The concentrations of dichlorodiphenytrichloroethane and its metabolites (DDTs), hexachlorobenzene (HCB), hexachlorocyclohexane isomers (HCHs), dieldrin, and 20 polychlorinated biphenyls (PCBs) were determined in 237 human breast milk samples collected from 12 locations in Tunisia. Gas chromatography with electron capture detector (GC-ECD) was used to identify and quantify residue levels on a lipid basis of organochlorine compounds (OCs). The predominant OCs in human breast milk were PCBs, p,p'-DDE, p,p'-DDT, HCHs, and HCB. Concentrations of DDTs in human breast milk from rural areas were significantly higher than those from urban locations (p<0.05). With regard to PCBs, we observed the predominance of mid-chlorinated congeners due to the presence of PCBs with high K(ow) such as PCB 153, 138, and 180. Positive correlations were found between concentrations of OCs in human breast milk and age of mothers and number of parities, suggesting the influence of such factors on OC burdens in lactating mothers. The comparison of daily intakes of PCBs, DDTs, HCHs, and HCB to infants through human breast milk with guidelines proposed by WHO and Health Canada shows that some individuals accumulated OCs in breast milk close to or higher than these guidelines. PMID:18614165

  9. Distribution of polychlorinated biphenyls and organochlorine pesticides in human breast milk from various locations in Tunisia: Levels of contamination, influencing factors, and infant risk assessment

    SciTech Connect

    Ennaceur, S. Gandoura, N.; Driss, M.R.

    2008-09-15

    The concentrations of dichlorodiphenytrichloroethane and its metabolites (DDTs), hexachlorobenzene (HCB), hexachlorocyclohexane isomers (HCHs), dieldrin, and 20 polychlorinated biphenyls (PCBs) were determined in 237 human breast milk samples collected from 12 locations in Tunisia. Gas chromatography with electron capture detector (GC-ECD) was used to identify and quantify residue levels on a lipid basis of organochlorine compounds (OCs). The predominant OCs in human breast milk were PCBs, p,p'-DDE, p,p'-DDT, HCHs, and HCB. Concentrations of DDTs in human breast milk from rural areas were significantly higher than those from urban locations (p<0.05). With regard to PCBs, we observed the predominance of mid-chlorinated congeners due to the presence of PCBs with high K{sub ow} such as PCB 153, 138, and 180. Positive correlations were found between concentrations of OCs in human breast milk and age of mothers and number of parities, suggesting the influence of such factors on OC burdens in lactating mothers. The comparison of daily intakes of PCBs, DDTs, HCHs, and HCB to infants through human breast milk with guidelines proposed by WHO and Health Canada shows that some individuals accumulated OCs in breast milk close to or higher than these guidelines.

  10. Influence of packaging information on consumer liking of chocolate milk.

    PubMed

    Kim, M K; Lopetcharat, K; Drake, M A

    2013-08-01

    Chocolate milk varies widely in flavor, color, and viscosity, and liking is influenced by these properties. Additionally, package labels (declared fat content) and brand are some of the extrinsic factors that may influence consumer perception. The objective of this study was to evaluate the effects of packaging labels and brand name on consumer liking and purchase intent of chocolate milk. A consumer acceptance test, conjoint analysis survey, and Kano analysis were conducted. One hundred eight consumers evaluated 7 chocolate milks with and without brand or package information in a 2-d crossover design. A conjoint analysis survey and Kano analysis were conducted after the consumer acceptance test. Results were evaluated by 2-way ANOVA and multivariate analyses. Declared fat content and brand influenced overall liking and purchase intent for chocolate milks to differing degrees. A subsequent conjoint analysis (n=250) revealed that fat content was a driver of choice for purchasing chocolate milk followed by sugar content and brand. Brand name was less important for purchase intent of chocolate milk than fat or sugar content. Among fat content of chocolate milk, 2 and 1% fat level were most appealing to consumers, and reduced sugar and regular sugar were equally important for purchase intent. Kano analysis confirmed that fat content (whole milk, 1, or 2% fat chocolate milk) was an attractive attribute for consumer satisfaction, more so than brand. Organic labeling did not affect the purchase decision of chocolate milk; however, Kano results revealed that having an organic label on a package positively influenced consumer satisfaction. Findings from this study can help chocolate milk producers as well as food marketers better target their product labels with attributes that drive consumer choice of chocolate milk. PMID:23706490

  11. Factors associated with increased milk production for automatic milking systems.

    PubMed

    Tremblay, Marlène; Hess, Justin P; Christenson, Brock M; McIntyre, Kolby K; Smink, Ben; van der Kamp, Arjen J; de Jong, Lisanne G; Döpfer, Dörte

    2016-05-01

    Automatic milking systems (AMS) are increasingly popular throughout the world. Our objective was to analyze 635 North American dairy farms with AMS for (risk) factors associated with increased milk production per cow per day and milk production per robot per day. We used multivariable generalized mixed linear regressions, which identified several significant risk factors and interactions of risk factors associated with milk production. Free traffic was associated with increased production per cow and per robot per day compared with forced systems, and the presence of a single robot per pen was associated with decreased production per robot per day compared with pens using 2 robots. Retrofitted farms had significantly less production in the first 4 yr since installation compared with production after 4 yr of installation. In contrast, newly built farms did not see a significant change in production over time since installation. Overall, retrofitted farms did not produce significantly more or less milk than newly constructed farms. Detailed knowledge of factors associated with increased production of AMS will help guide future recommendations to producers looking to transition to an AMS and maximize their production. PMID:26898275

  12. Derivation of factors to estimate daily milk yield from one milking of cows milked three times daily

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The objective was to derive factors to predict daily milk yield when milk is sampled once per d for cows milked three times (3x) per d. Milk weights for all three milkings were recorded automatically by 8 herds and collected by Dairy Herd Improvement supervisors on test-day. Following edits, 196,725...

  13. Factors associated with marketable milk production recovery after treatment of naturally occurring acute coliform mastitis.

    PubMed

    Shinozuka, Yasunori; Kaneko, Sohei; Kurose, Tomoyasu; Watanabe, Aiko; Kuruhara, Kana; Kawai, Kazuhiro

    2016-06-01

    Milk production loss after recovery from acute coliform mastitis causes major economic losses for dairy industries. Declines in milk production and composition are caused by multiple factors, including cow factors, microorganisms and treatments, but the influence of each factor has not been determined. To investigate risk factors for milk loss after treatment for acute coliform mastitis, multiple logistic regression analyses were conducted in 53 clinical cases. Systemic administration of fluoroquinolone was significantly associated with recovery of marketable milk production. The time to slaughter was significantly shorter in cows with complete loss of quarter milk production than in cows that produced marketable milk. In this study, we identified factors associated with increased risk of milk production loss. PMID:26860356

  14. Factors associated with marketable milk production recovery after treatment of naturally occurring acute coliform mastitis

    PubMed Central

    SHINOZUKA, Yasunori; KANEKO, Sohei; KUROSE, Tomoyasu; WATANABE, Aiko; KURUHARA, Kana; KAWAI, Kazuhiro

    2016-01-01

    Milk production loss after recovery from acute coliform mastitis causes major economic losses for dairy industries. Declines in milk production and composition are caused by multiple factors, including cow factors, microorganisms and treatments, but the influence of each factor has not been determined. To investigate risk factors for milk loss after treatment for acute coliform mastitis, multiple logistic regression analyses were conducted in 53 clinical cases. Systemic administration of fluoroquinolone was significantly associated with recovery of marketable milk production. The time to slaughter was significantly shorter in cows with complete loss of quarter milk production than in cows that produced marketable milk. In this study, we identified factors associated with increased risk of milk production loss. PMID:26860356

  15. Factors associated with coliform count in unpasteurized bulk milk.

    PubMed

    Pantoja, J C F; Reinemann, D J; Ruegg, P L

    2011-06-01

    The objective of this study was to identify factors associated with bulk milk coliform count (CC). Dairy farms (n=10) were visited once weekly on sequential weekdays over a period of 10 wk. During each visit, in-line drip samplers were used to collect 1 milk sample from 2 points of the milk line (between the receiver jar and milk filters, and after the plate cooler). During the same period that in-line milk samples were collected, university personnel observed milking performance and hygiene and collected liner (n=40) and teat skin swabs (n=40). Coliform counts were determined for milk samples and swabs using Petrifilm CC plates (3M, St. Paul, MN). A mixed model was used to assess the association between in-line milk CC (ILCC) and several potential predictor variables. The mean duration of each visit was 73 min and the time between start of milking and beginning of milk sampling was 154 min. The mean number of cows milked during each visit was 236. For all milk samples (n=181), geometric mean ILCC was 37 cfu/mL. In-line milk CC varied by farm, ranging from 5 to 1,198 cfu/mL. Rate of fall-offs, rate of cluster washes, outdoor and indoor temperature, indoor humidity, sampling duration, and parity group were unconditionally associated with ILCC but did not enter the final multivariate model. In-line milk CC was 4 times greater (115 cfu/mL) when milking machine wash failures occurred compared with ILCC after normal washes (26 cfu/mL). Pre-filter and post-cooler ILCC were not different when milk samples were collected at the beginning (<33% of herd milked) or at mid-milking (33 to 66% of the herd milked), whereas pre-filter ILCC was less than post-cooler for samples collected at the end of milking (>67% of the herd milked). Geometric mean ILCC (cfu/mL) increased 6.3% for every 10% increase in in-line milk SCC (cells/mL). Geometric mean ILCC increased 2.3% for every 10% increase in liner CC (cfu/mL). Results of this study provide novel information about farm factors

  16. Factors affecting breast milk composition and potential consequences for development of the allergic phenotype.

    PubMed

    Munblit, D; Boyle, R J; Warner, J O

    2015-03-01

    There is conflicting evidence on the protective role of breastfeeding in relation to allergic sensitization and disease. The factors in breast milk which influence these processes are still unclear and under investigation. We know that colostrum and breast milk contain a variety of molecules which can influence immune responses in the gut-associated lymphoid tissue of a neonate. This review summarizes the evidence that variations in colostrum and breast milk composition can influence allergic outcomes in the infant, and the evidence that maternal and environmental factors can modify milk composition. Taken together, the data presented support the possibility that maternal dietary interventions may be an effective way to promote infant health through modification of breast milk composition. PMID:25077553

  17. Derivation of factors to estimate daily fat, protein, and somatic cell score from one milking of cows milked twice daily

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The objective was to derive factors to predict daily fat (F) and protein (P) yield or somatic cell score (SCS) when milk is sampled once for cows milked twice per d. Milk samples were collected for each milking on test-day by Dairy Herd Improvement personnel from herds recording milking times and m...

  18. Grazing season and forage type influence goat milk composition and rennet coagulation properties.

    PubMed

    Inglingstad, R A; Steinshamn, H; Dagnachew, B S; Valenti, B; Criscione, A; Rukke, E O; Devold, T G; Skeie, S B; Vegarud, G E

    2014-01-01

    Two different types of pasture (cultivated and rangeland) and 2 different hay qualities (high and low quality) were examined for their effects on goat milk composition and rennet coagulation properties. Furthermore, the effect of dietary treatments in both the early and late grazing season was studied. As lactation stage is known to influence milk composition, the goats in the early and late grazing season were in the same lactation stage at the start of the experiment. The milk composition was influenced both by dietary treatment and season. Milk from goats on pasture was superior to those on hay by containing a higher content of protein and casein, and the goats on cultivated pasture had the highest milk yield. Casein composition was significantly influenced by forage treatment. Goats grazing on cultivated pasture had higher contents of αs1-casein and also of κ-casein compared with the other treatments, whereas goats grazing on rangeland had the highest content of β-casein. Factors such as milk yield, casein micelle size, αs2-casein, and calcium content were reduced in late compared with early season. More favorable rennet coagulation properties were achieved in milk from the early grazing season, with shorter firming time and higher curd firmness compared with milk from the late grazing season, but the firming time and curd firmness were not prominently influenced by forage treatment. The content of αs2-casein and calcium in the milk affected the firming time and the curd firmness positively. The influence of season and forage treatment on especially milk yield, casein content, and rennet coagulation properties is of economic importance for both the dairy industry and goat milk farmers. PMID:24704223

  19. Analysis of factors affecting milking claw vacuum levels using a simulated milking device.

    PubMed

    Enokidani, Masafumi; Kuruhara, Kana; Kawai, Kazuhiro

    2016-06-01

    Bovine mastitis is typically caused by microbial infection of the udder, but the factors responsible for this condition are varied. One potential cause is the milking system, and although previous studies have investigated various methods for inspecting these devices, most have not assessed methods for evaluating the milking units. With this in mind, we analyzed the factors that affect the vacuum inside the milking claw by using a simulated milking device and by measuring milking claw vacuum when adjusting the flow rate in five stages. The factors analyzed in each milking system were the vacuum pressure settings (high and low line system) , milk tube length (200-328 cm), aperture diameter (14-22.2 mm), constricted aperture diameter (12 mm), tubing configurations, lift formation (0-80 cm), claw type (bottom and top flow) and use or non-use of a milk sampler. The study findings demonstrated that all of these variables had a significant impact on claw vacuum and suggest that a diagnostic method using a simulated milking device should be considered when inspecting modern milking systems. PMID:26336796

  20. Diurnal differences in milk composition and its influence on in vitro growth of Staphylococcus aureus and Escherichia coli in bovine quarter milk.

    PubMed

    Eisenberg, S W F; Boerhout, E M; Ravesloot, L; Daemen, A J J M; Benedictus, L; Rutten, V P M G; Koets, A P

    2016-07-01

    In experimental intramammary inoculation studies, it has been observed that mastitis susceptibility is influenced, among others, by cow factors. To identify milk characteristics leading to these differences, quarter milk samples of morning and evening milk were collected and analyzed for their composition (protein, fat, lactose, urea, lactoferrin, lactoperoxidase, and β-lactoglobulin concentrations), somatic cell count, and antibodies against Staphylococcus aureus. Furthermore, in vitro growth of S. aureus and Escherichia coli in fresh quarter milk samples was determined. All measured parameters differed significantly between quarters and also between morning and evening milk with the exception of lactose levels. In addition, quantitative growth of S. aureus and E. coli was significantly different in morning milk compared with evening milk. Mixed model analysis revealed that replication of S. aureus was negatively associated with the presence of fat, S. aureus-specific IgG1 antibodies, contamination of the milk sample and morning milk. Replication of E. coli was negatively associated with fat concentrations, and positively associated with morning milk. The significant difference between morning and evening milk supports the theory that changes in milk composition influence bacterial growth. Although all determined milk components differed significantly between quarters and in time no significant association with bacterial growth could be identified with the exception of fat for both studied species and IgG1 titers for S. aureus. The negative association of fat with bacterial growth was assumed to occur due to activation of lipolysis by milk handling and can most likely be neglected for in vivo relevance. The fact that S. aureus-specific IgG1 titers were negatively associated with S. aureus growth in vitro encourages the ongoing effort to develop a vaccine against S. aureus-induced mastitis. PMID:27132103

  1. Some Factors Influencing Dairy Practice Adoption by Grade A Milk Producers in Selected Tennessee Counties. A Research Summary of a Graduate Study.

    ERIC Educational Resources Information Center

    Griffin, Anthony C.; And Others

    A study was conducted to determine the relationships between Grade A dairy producers' milk production levels and size of herd and their use of 21 milk production practices recommended by the University of Tennessee. The population consisted of 405 Grade A dairymen in 42 Tennessee counties. The extension agent in each county interviewed 10 or more…

  2. Life cycle assessment of milk production from commercial dairy farms: the influence of management tactics.

    PubMed

    Yan, M-J; Humphreys, J; Holden, N M

    2013-07-01

    Little consideration has been given to how farm management, specifically tactics used to implement the management strategy, may influence the carbon footprint (CF) and land use for milk produced on commercial farms. In this study, the CF and land use of milk production from 18 Irish commercial dairy farms were analyzed based on foreground data from a 12-mo survey capturing management tactics and background data from the literature. Large variation was found in farm attributes and management tactics; for example, up to a 1.5-fold difference in fertilizer nitrogen input was used to support the same stocking density, and up to a 3.5-fold difference in concentrate fed for similar milk output per cow. However, the coefficient of variation for milk CF between farms only varied by 13% and for land use by 18%. The overall CF and overall land use of the milk production from the 18 dairy farms was 1.23±0.04kg of CO2 Eq and 1.22±0.05 m(2) per kilogram of energy-corrected milk. Milk output per cow, economic allocation between exports of milk and liveweight, and on-farm diesel use per ha were found to be influential factors on milk CF, whereas the fertilizer N rate, milk output per cow, and economic allocation between exports of milk and liveweight were influential on land use. Effective sward management of white clover within a few farms appeared to lower the CF but increased on-farm land use. It was concluded that a combination of multiple tactics determines CF and land use for milk production on commercial dairy farms and, although these 2 measures of environmental impact are correlated, a farm with a low CF did not always have low land use and vice versa. PMID:23660142

  3. Derivation of factors to estimate daily yield from single milkings for Holsteins milked two or three times daily

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The objective was to derive factors to predict daily yield when milk weights are recorded once when cows are milked twice (2x) or once or twice when cows are milked thrice (3x) per d. Data was from herds enrolled in DHI and automatically recording milking weights and times. Following edits, 83,690...

  4. Human Milk Composition: Nutrients and Bioactive Factors

    PubMed Central

    Ballard, Olivia; Morrow, Ardythe L.

    2013-01-01

    Synopsis The composition of human milk is the biologic norm for infant nutrition. Human milk also contains many hundreds to thousands of distinct bioactive molecules that protect against infection and inflammation and contribute to immune maturation, organ development, and healthy microbial colonization. Some of these molecules, e.g., lactoferrin, are being investigated as novel therapeutic agents. A dynamic, bioactive fluid, human milk changes in composition from colostrum to late lactation, and varies within feeds, diurnally, and between mothers. Feeding infants with expressed human milk is increasing. Pasteurized donor milk is now commonly provided to high risk infants and most mothers in the U.S. express and freeze their milk at some point in lactation for future infant feedings. Many milk proteins are degraded by heat treatment and freeze-thaw cycles may not have the same bioactivity after undergoing these treatments. This article provides an overview of the composition of human milk, sources of its variation, and its clinical relevance. PMID:23178060

  5. Review-Factors involving in fluctuation of trace metals concentrations in bovine milk.

    PubMed

    Perween, Rubina

    2015-05-01

    Milk makes a significant contribution to human diet through provision of macronutrients, vitamins and minerals. The exact composition of milk varies with species among domestic animals according to their neonatal needs. It is recognized that imbalance in the quantity of minerals and trace elements is a serious health hazard especially for infants. Many studies reported the fluctuation in the level of metals in milk due to the influence of several factors such as geographical and exposure to environmental pollution caused by anthropogenic activity. Amongst all sources, industries take lion's share to alter the metal content in milk. The importance of different nutritional and toxic metals in milk from different geographical areas is discussed. PMID:26004711

  6. Pancreatic secretory trypsin inhibitor is a major motogenic and protective factor in human breast milk.

    PubMed

    Marchbank, Tania; Weaver, Gillian; Nilsen-Hamilton, Marit; Playford, Raymond J

    2009-04-01

    Colostrum is the first milk produced after birth and is rich in immunoglobulins and bioactive molecules. We examined whether human colostrum and milk contained pancreatic secretory trypsin inhibitor (PSTI), a peptide of potential relevance for mucosal defense and, using in vitro and in vivo models, determined whether its presence influenced gut integrity and repair. Human milk was collected from individuals over various times from parturition and PSTI concentrations determined with the use of immunoassay. Human milk samples were analyzed for proliferation and promigratory activity (wounded monolayers) and antiapoptotic activity (caspase-3 activity) with the use of intestinal HT29 cells with or without neutralizing antibodies to PSTI and epidermal growth factor (EGF). Rats were restrained and given indomethacin to induce gastric injury. Effect of gavage with human breast milk with or without neutralizing antibodies on amount of injury were compared with animals receiving a commercial formula feed. PSTI is secreted into human milk, with colostrum containing a much higher concentration of PSTI than human milk obtained later. Human milk stimulated migration and proliferation about threefold and reduced indomethacin-induced apoptosis by about 70-80%. Sixty-five percent of the migratory effect of human milk could be removed by immunoneutralization of PSTI. PSTI worked synergistically with EGF in mediating these effects. Gastric damage in rats was reduced by about 75% in the presence of human milk and was more efficacious than the formula feed (P<0.001). Protective effects of the milk were reduced by about 60% by PSTI immunoneutralization. We concluded that PSTI is secreted into human milk at concentrations that have probable pathophysiological relevance. PMID:19147803

  7. The long-term impact of epigenetics and maternal influence on the neonate through milk-borne factors and nutrient status

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The goals of the symposium were to explore potential means by which colostrum and milk may affect growth and development of offspring immediately after birth, into adulthood, and in subsequent generations. The symposium was exceptional in that it brought together scientists that work in the broad ar...

  8. Reisolation of Staphylococcus aureus from bovine milk following experimental inoculation is influenced by fat percentage and specific immunoglobulin G1 titer in milk.

    PubMed

    Boerhout, E M; Koets, A P; Vernooij, J C M; Mols-Vorstermans, T G T; Nuijten, P J M; Rutten, V P M G; Bijlsma, J J E; Eisenberg, S W F

    2016-06-01

    The associations of management parameters, herd characteristics, and individual cow factors with bovine mastitis have been subject of many studies. The present study aimed to evaluate the association between milk composition parameters, including fat, protein, lactose, urea, and specific immunoglobulin levels, at the time of experimental bacterial inoculation of the mammary gland and subsequent shedding dynamics of Staphylococcus aureus. Sixty-eight cows were experimentally infected with S. aureus and closely monitored for 3 wk. Mixed model analyses were used to determine the influence of management and herd characteristics (farm and experimental group), individual cow factors (days in milk, milk yield, and quarter position), and a challenge-related parameter (inoculation dose) in combination with either the milk components fat, protein, lactose and urea, or the S. aureus-specific antibody isotype titers at the time of bacterial inoculation, on the number of S. aureus reisolated from milk after inoculation. A positive association was observed between the milk fat percentage and the number of S. aureus reisolated from quarter milk, and a negative relationship between the S. aureus-specific IgG1 titer in milk and the number of S. aureus. These findings should be considered in the development of a vaccine against S. aureus-induced bovine mastitis. PMID:26995117

  9. Contamination of polychlorinated biphenyls and organochlorine pesticides in breast milk in Korea: time-course variation, influencing factors, and exposure assessment.

    PubMed

    Lee, Sunggyu; Kim, Sunmi; Lee, Hyun-Kyung; Lee, In-Seok; Park, Jeongim; Kim, Hai-Joong; Lee, Jeong Jae; Choi, Gyuyeon; Choi, Sooran; Kim, Sungjoo; Kim, Su Young; Choi, Kyungho; Kim, Sungkyoon; Moon, Hyo-Bang

    2013-11-01

    Breast milk is a noninvasive specimen to assess maternal and infant exposure to polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs). In this study, 206 breast milk samples were collected from 87 participants during lactation, at <7, 15, 30, or 90 days postpartum in four cities in Korea. The total concentrations of PCBs (ΣPCB) and OCPs (ΣOCP) ranged from milk had a potential health risk which deserves further investigation. PMID:24112654

  10. Growth hormone releasing factor-like immunoreactivity in human milk.

    PubMed

    Werner, H; Amarant, T; Fridkin, M; Koch, Y

    1986-03-28

    The presence of immunoreactive growth hormone-releasing factor (GRF) in human milk has been demonstrated. By using sequential high performance liquid chromatography, it has been shown that most of the immunoreactivity co-elutes with the synthetic, hypothalamic-like, GRF (1-40). The concentrations of GRF detected (between 152 and 432 pg GRF/ml milk) exceed several fold its values in plasma. PMID:3083812

  11. Factors affecting milk ELISA scores of cows tested for Johne’s disease

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Infection with Mycobacterium avium subsp. paratuberculosis (Johne’s disease) has been estimated to cost dairy producers over $1.5 billion per year. The objective of this study was to examine the influence a number of environmental and genetic factors have on ELISA milk test scores for Johne’s diseas...

  12. A protective effect of milk fat globule EGF factor VIII (MFG-E8) on the spontaneous fusion of milk fat globules in breast milk.

    PubMed

    Yasueda, Takehiko; Oshima, Kenzi; Nakatani, Hajime; Tabuchi, Kanji; Nadano, Daita; Matsuda, Tsukasa

    2015-07-01

    Lipid droplets synthesized in mammary epithelial cells are secreted into breast milk by the budding-off mechanism. The milk lipids, termed mik fat globules (MFGs), are surrounded with the cell plasma membrane and contain various membrane proteins, including milk fat globule epidermal growth factor (EGF)-factor VIII (MFG-E8), on their surface. We report here that the MFGs in the milk of MFG-E8-deficient mice fused each other and turned into abnormally large size of lipid droplets within ∼48 h after being secreted into mammary alveolar lumen in situ or being incubated at 37°C in vitro. This biophysical degeneration of MFGs in the MFG-E8-deficient milk was efficiently rescued in vitro by adding the milk serum of wild-type mice, isolated MFG-E8 or annexin V. Moreover, addition of ethylenediaminetetraacetic acid (30 mM) also protected the MFG fusion remarkably in vitro. In addition, bovine MFGs also fused each other when isolated from milk serum, and the fusion was inhibited by adding isolated MFG-E8 or mouse milk serum, but not the milk serum of MFG-E8-deficient mice. MFG-E8 in breast milk may mask the phosphatidylserine exposed on the surface of MFGs with time after secretion and thereby suppress the membrane fusion among MFGs resulting in the enlargement of MFGs in the breast milk. PMID:25661589

  13. Factors affecting conjugated linoleic acid content in milk and meat.

    PubMed

    Dhiman, Tilak R; Nam, Seung-Hee; Ure, Amy L

    2005-01-01

    Conjugated linoleic acid (CLA) has been recently studied mainly because of its potential in protecting against cancer, atherogenesis, and diabetes. Conjugated linoleic acid (CLA) is a collective term for a series of conjugated dienoic positional and geometrical isomers of linoleic acid, which are found in relative abundance in milk and tissue fat of ruminants compared with other foods. The cis-9, trans-11 isomer is the principle dietary form of CLA found in ruminant products and is produced by partial ruminal biohydrogenation of linoleic acid or by endogenous synthesis in the tissues themselves. The CLA content in milk and meat is affected by several factors, such as animal's breed, age, diet, and management factors related to feed supplements affecting the diet. Conjugated linoleic acid in milk or meat has been shown to be a stable compound under normal cooking and storage conditions. Total CLA content in milk or dairy products ranges from 0.34 to 1.07% of total fat. Total CLA content in raw or processed beef ranges from 0.12 to 0.68% of total fat. It is currently estimated that the average adult consumes only one third to one half of the amount of CLA that has been shown to reduce cancer in animal studies. For this reason, increasing the CLA contents of milk and meat has the potential to raise the nutritive and therapeutic values of dairy products and meat. PMID:16183568

  14. Influences of stage of lactation, teat position and sequential milk sampling on the composition of domestic cat milk (Felis catus).

    PubMed

    Jacobsen, K L; DePeters, E J; Rogers, Q R; Taylor, S J

    2004-02-01

    Milk from 11 domestic shorthair cats (Felis catus; n=7 fed dry low-fat diet, n=4 fed dry high-fat diet) was collected weekly for 6 weeks following parturition, and analysed for total solids (TS), crude protein (CP), fat, lactose and ash. Samples were collected in 1-ml sequential fractions to determine whether within-sampling changes in composition existed Samples of extracted milk fat were also analysed for fatty acid content. Two commercia kitten milk replacers were analysed according to the same procedures utilized for mil samples. In statistical analyses individual cat, diet, stage of lactation, litter size, and teat position influenced concentrations of milk components; parity and sequential sampling had no effect. Averaged cat milk was 27.9% TS, and 8.7% CP, 12.7% fat, 4.2% lactose and 1.3% ash (on a wet basis). Milk protein percentage increased over lactation for both diet groups, but fat percentage increased only for queens fed the high-fat diet. Milk replacers were lower in fat and protein content than milk from queens, and had considerably lower levels of arachidonic acid. Data from this study contribute to the limited information available regarding the composition of domestic cat milk, and give possible reasons for poor growth occasionally observed in kittens fed unsupplemented commercial milk replacers. PMID:19774762

  15. Immune factors and fatty acid composition in human milk from river/lake, coastal and inland regions of China.

    PubMed

    Urwin, Heidi J; Zhang, Jian; Gao, Yixiong; Wang, Chunrong; Li, Lixiang; Song, Pengkun; Man, Qingqing; Meng, Liping; Frøyland, Livar; Miles, Elizabeth A; Calder, Philip C; Yaqoob, Parveen

    2013-06-01

    Breast milk fatty acid composition may be affected by the maternal diet during gestation and lactation. The influence of dietary and breastmilk fatty acids on breast milk immune factors is poorly defined. We determined the fatty acid composition and immune factor concentrations of breast milk from women residing in river/lake, coastal and inland regions of China, which differ in their consumption of lean fish and oily fish. Breast milk samples were collected on days 3–5 (colostrum), 14 and 28 post-partum (PP) and analysed for soluble CD14 (sCD14), transforming growth factor (TGF)-b1, TGF-b2, secretory IgA (sIgA) and fatty acids. The fatty acid composition of breast milk differed between the regions and with time PP. The concentrations of all four immune factors in breast milk decreased over time, with sCD14, sIgA and TGF-b1 being highest in the colostrum in the river and lake region. Breast milk DHA and arachidonic acid (AA) were positively associated, and g-linolenic acid and EPA negatively associated, with the concentrations of each of the four immune factors. In conclusion, breast milk fatty acids and immune factors differ between the regions in China characterised by different patterns of fish consumption and change during the course of lactation. A higher breast milk DHA and AA concentration is associated with higher concentrations of immune factors in breast milk, suggesting a role for these fatty acids in promoting gastrointestinal and immune maturation of the infant. PMID:23148871

  16. Methionine sulfoxide profiling of milk proteins to assess the influence of lipids on protein oxidation in milk.

    PubMed

    Wüst, Johannes; Pischetsrieder, Monika

    2016-06-15

    Thermal treatment of milk and milk products leads to protein oxidation, mainly the formation of methionine sulfoxide. Reactive oxygen species, responsible for the oxidation, can be generated by Maillard reaction, autoxidation of sugars, or lipid peroxidation. The present study investigated the influence of milk fat on methionine oxidation in milk. For this purpose, quantitative methionine sulfoxide profiling of all ten methionine residues of β-lactoglobulin, α-lactalbumin, and αs1-casein was carried out by ultrahigh-performance liquid chromatography-electrospray ionization tandem mass spectrometry with scheduled multiple reaction monitoring (UHPLC-ESI-MS/MS-sMRM). Analysis of defatted and regular raw milk samples after heating for up to 8 min at 120 °C and analysis of ultrahigh-temperature milk samples with 0.1%, 1.5%, and 3.5% fat revealed that methionine oxidation of the five residues of the whey proteins and of residues M 123, M 135, and M 196 of αs1-casein was not affected or even suppressed in the presence of milk fat. Only the oxidation of residues M 54 and M 60 of αs1-casein was promoted by lipids. In evaporated milk samples, formation of methionine sulfoxide was hardly influenced by the fat content of the samples. Thus, it can be concluded that lipid oxidation products are not the major cause of methionine oxidation in milk. PMID:26927981

  17. Recombinant Human Factor IX Produced from Transgenic Porcine Milk

    PubMed Central

    Lee, Meng-Hwan; Lin, Yin-Shen; Tu, Ching-Fu; Yen, Chon-Ho

    2014-01-01

    Production of biopharmaceuticals from transgenic animal milk is a cost-effective method for highly complex proteins that cannot be efficiently produced using conventional systems such as microorganisms or animal cells. Yields of recombinant human factor IX (rhFIX) produced from transgenic porcine milk under the control of the bovine α-lactalbumin promoter reached 0.25 mg/mL. The rhFIX protein was purified from transgenic porcine milk using a three-column purification scheme after a precipitation step to remove casein. The purified protein had high specific activity and a low ratio of the active form (FIXa). The purified rhFIX had 11.9 γ-carboxyglutamic acid (Gla) residues/mol protein, which approached full occupancy of the 12 potential sites in the Gla domain. The rhFIX was shown to have a higher isoelectric point and lower sialic acid content than plasma-derived FIX (pdFIX). The rhFIX had the same N-glycosylation sites and phosphorylation sites as pdFIX, but had a higher specific activity. These results suggest that rhFIX produced from porcine milk is physiologically active and they support the use of transgenic animals as bioreactors for industrial scale production in milk. PMID:24955355

  18. Cow level sampling factors affecting analysis and interpretation of milk urea concentrations in 2 dairy herds.

    PubMed Central

    Eicher, R; Bouchard, E; Tremblay, A

    1999-01-01

    The goals of this study were to determine the influence of the variations among udder quarters, the somatic cell count, the time of sampling during the day, sample conservation, and centrifugation on milk urea (UREA) concentrations, and to propose a sample collection procedure for herds that are not on a Dairy Herd Improvement (DHI) program. Forty cows from 2 herds with different feeding practices were randomly selected. The quarter sampled and the somatic cell count did not significantly influence UREA concentrations. Milk urea concentrations were highest in the morning. The diurnal pattern was not influenced by intrinsic factors like parity, days postpartum, or daily milk yield. The UREA concentrations were significantly higher after refrigeration for one week (mean UREA change = +0.41 +/- 0.24 mmol/L, P = 0.0001) and freezing for one month (mean UREA change = +1.52 +/- 1.25 mmol/L, P = 0.0001). Urea concentrations were slightly higher in lactoserum than in whole milk (mean UREA difference = +0.17 +/- 0.24 mmol/L, P = 0.0001). Although this study included only 2 herds and does not allow extrapolation, differences were found in the diurnal pattern of UREA in these 2 herds, which possibly reflect differences in feeding strategy. With consideration of these results, a 6-point sampling procedure for herds that are not on a DHI program is proposed. PMID:10416068

  19. Derivation of factors to estimate daily, fat, protein, and somatic cell score from one milking of cows milked three times daily

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The objective was to derive factors to predict daily fat (F) and protein (P) yield and somatic cell score (SCS) when milk is sampled once per d for cows milked three times (3x) per d. Daily milk weights were recorded automatically and samples were collected from 8 herds for each milking on test-day ...

  20. Influence of intramammary infection of a single gland in dairy cows on the cow's milk quality.

    PubMed

    Bezman, Dror; Lemberskiy-Kuzin, Liubov; Katz, Gil; Merin, Uzi; Leitner, Gabriel

    2015-08-01

    Intramammary infection (IMI), comprises a group of costly diseases affecting dairy animals worldwide. Many dairy parlours are equipped with on-line computerised data acquisition systems designed to detect IMI. However, the data collected is related to the cow level, therefore the contribution of infected glands to the recorded parameters may be over estimated. The present study aimed at evaluating the influence of single gland IMI by different bacteria species on the cow's overall milk quality. A total of 130 cows were tested 239 times; 79 cows were tested once and the others were examined 2-8 times. All of the analysed data refer to the number of tests performed, taking into account the repeated testing of the same cows. Of the cows tested ~50% were free of infection in all 4 glands and the others were infected in one gland with different coagulase negative staphylococci (CNS), Streptococcus dysgalactiae, or were post infected with Escherichia coli (PIEc), i.e., free of bacterial infection at the time of sampling but 1-2 months after clinical infection by E. coli. Overall, infection with bacteria had significant effects on somatic cell count (SCC) and lactose concentration. Examining each bacterium reveals that the major influence on those parameters was the sharp decrease in lactose in the PIEc and curd firmness in PIEc and Strep. Individual gland milk production decreased ~20% in Strep. dysgalactiae- and ~50% in PIEc-infected glands with respect to glands with no bacterial findings. Significant differences were found in lactose, SCC, rennet clotting time and curd firmness in the milk of infected glands and among those, these parameters were significantly higher in Strep. dysgalactiae and PIEc than in CNS infected cows. The current results using quarter-milking reinforces the importance of accurate IMI detection in relation to economic and welfare factors, and moreover, emphasises the need for technical sensing and constant reporting to the farmer about changes

  1. Relationship between involvement and functional milk desserts intention to purchase. Influence on attitude towards packaging characteristics.

    PubMed

    Ares, Gastón; Besio, Mariángela; Giménez, Ana; Deliza, Rosires

    2010-10-01

    Consumers perceive functional foods as member of the particular food category to which they belong. In this context, apart from health and sensory characteristics, non-sensory factors such as packaging might have a key role on determining consumers' purchase decisions regarding functional foods. The aims of the present work were to study the influence of different package attributes on consumer willingness to purchase regular and functional chocolate milk desserts; and to assess if the influence of these attributes was affected by consumers' level of involvement with the product. A conjoint analysis task was carried out with 107 regular milk desserts consumers, who were asked to score their willingness to purchase of 16 milk dessert package concepts varying in five features of the package, and to complete a personal involvement inventory questionnaire. Consumers' level of involvement with the product affected their interest in the evaluated products and their reaction towards the considered conjoint variables, suggesting that it could be a useful segmentation tool during food development. Package colour and the presence of a picture on the label were the variables with the highest relative importance, regardless of consumers' involvement with the product. The importance of these variables was higher than the type of dessert indicating that packaging may play an important role in consumers' perception and purchase intention of functional foods. PMID:20609376

  2. Factors affecting milk flow traits in dairy cows: results of a field study.

    PubMed

    Sandrucci, A; Tamburini, A; Bava, L; Zucali, M

    2007-03-01

    The study of milk flow curves provides useful information for enhancing milking efficiency and protecting udder health by adapting milking machine and milking procedures to the physiological requirements of the cow. The aim of this experiment was to investigate, using field data, the relationships among traits of the milk flow curves, their sources of variation, and milking performances in terms of milk production, machine-on time, and udder health. A total of 2,486 milk flow curves of the whole udder were collected in 82 Italian Holstein-Friesian dairy herds in the Lombardy region of Italy. Approximately one-third (35.1%) of milk flow curves were classified as bimodal. Most flow characteristics were influenced by lactation number, days in milk, and peak flow but also strongly affected by premilking operations. Proper udder preparation, including forestripping and predipping, resulted in better milking performances compared with poor preparation, with greater milk yield per milking, shorter milking time, and lesser bimodality. Premilking delay time, between the start of teat stimulation and cup attachment, affected milking time significantly: The shortest milking time was obtained for a range of delay time between 1 and 60 s. As the delay time increased, the percentage of bimodality dropped significantly. Increasing the number of clusters per operator led to greater percentages of bimodal curves. The greater somatic cell count of cows with bimodal curves supports the hypothesis of the negative effect of bimodality on udder health and indicates the importance of avoiding its occurrence using proper pre-milking procedures. PMID:17297090

  3. Transforming growth factor (TGF)-. alpha. in human milk

    SciTech Connect

    Okada, Masaki; Wakai, Kae; Shizume, Kazuo ); Iwashita, Mitsutoshi ); Ohmura, Eiji; Kamiya, Yoshinobu; Murakami, Hitomi; Onoda, Noritaka; Tsushima, Toshio

    1991-01-01

    Transforming growth factor (TGF)-{alpha} and epidermal growth factor (EGF) were measured in human milk by means of homologous radioimmunoassay. As previously reported, EGF concentration in the colostrum was approximately 200 ng/ml and decreased to 50 ng/ml by day 7 postpartum. The value of immunoreactive (IR)-TGF-{alpha} was 2.2-7.2 ng/ml, much lower than that of EGF. In contrast to EGF, the concentration of IR-TGF-{alpha} was fairly stable during the 7 postpartum days. There was no relationship between the concentrations of IR-TGF-{alpha} and IR-EGF, suggesting that the regulatory mechanism in the release of the two growth factors is different. On gel-chromatography using a Sephadex G-50 column, IR-EGF appeared in the fraction corresponding to that of authentic human EGF, while 70%-80% of the IR-TGF-{alpha} was eluted as a species with a molecular weight greater than that of authentic human TGF-{alpha}. Although the physiological role of TGF-{alpha} in milk is not known, it is possible that it is involved in the development of the mammary gland and/or the growth of newborn infants.

  4. Influence of milk urea concentration on fractional urea disappearance rate from milk to blood plasma in dairy cows.

    PubMed

    Spek, J W; Dijkstra, J; Bannink, A

    2016-05-01

    The relationship between milk urea nitrogen (MUN; mg of N/dL) and urinary N excretion is affected, among others, by diurnal dynamics in MUN, which in turn is largely influenced by feed intake pattern and characteristics of urea transfer from blood plasma to milk and vice versa. This study aimed to obtain insight in urea transfer characteristics within the mammary gland and from the mammary gland to blood plasma in dairy cows at various concentrations of plasma urea nitrogen (PUN; mg of N/dL) and MUN. Urea transfer from milk to blood plasma and urea transfer within the mammary gland itself was evaluated in a 4×4 Latin square design using 4 lactating multiparous Holstein-Friesian cows (milk production of 39.8±4.70kg/d and 90±3.9 d in milk). Treatments consisted of 4 primed continuous intravenous urea infusions of 0, 5, 10, and 15g of urea/h. Boluses of [(15)N(15)N]urea were injected in cistern milk at 20, 60, and 100 min before the 1700h milking. Milk was collected in portions of approximately 2 L at the 1700h milking. Milk samples were analyzed for urea and enrichment of (15)N-urea. Results from one cow were discarded because of leakage of milk from the teats after injection of boluses of [(15)N(15)N]urea. Increasing urea infusion rate linearly increased PUN from 11.4 (0g of urea/h) to 25.9mg/dL (15g of urea/h) and MUN from 10.3 (0g of urea/h) to 23.5 (15g of urea/h) mg of N/dL. The percentage of injected [(15)N(15)N]urea recovered from milk at the time of injection was not affected by urea infusion rate and varied between 65.1 and 73.0%, indicating that a substantial portion of injected [(15)N(15)N]urea was not accounted for by collected milk. The estimated fractional disappearance rate of (15)N-urea from milk to blood (Kurea; per hour) linearly increased from 0.429 (0g of urea/h) to 0.641 per hour (15g of urea/h). Cistern injected [(15)N(15)N]urea diffused within 20 min after injection toward alveoli milk. Calculations with the average Kurea estimated in this

  5. The influence of nalidixic acid on Escherichia coli growth in milk.

    PubMed

    Tyczyńska, B; Bassalik-Chabielska, L

    1987-01-01

    The high antibacterial activity of nalidixic acid against Escherichia coli, cultivated in raw and pasteurized milk has been shown. The low oxygen reduction potential had no influence on the antibacterial activity of this drug. The natural antibacterial agents in active milk from an inflamed udder have reduced the efficacy of nalidixic acid inhibition of the growth of E. coli. PMID:2447751

  6. [Human milk and various resistence factors against infections].

    PubMed

    Cravioto, J; Arrieta-Milán, R

    1980-07-01

    The statement that breast milk can provide infants with better resistence against infections stems from 3 main lines of investigation: 1) biochemical, immunologic, and bacteriologic analyses of breast milk and of the feces of breast fed infants; 2) epidemiological studies on infant morbidity and mortality of children fed with breast milk or with cow milk; and, 3) the study of dozens of clinical cases. This long article examines data from all kinds of studies, especially regarding immunization against infant diarrhea, and suggests a few possible lines of investigation on the advantages of breast milk. PMID:7429077

  7. Oxidative stability of milk influenced by fatty acids, antioxidants, and copper derived from feed.

    PubMed

    Havemose, M S; Weisbjerg, M R; Bredie, W L P; Poulsen, H D; Nielsen, J H

    2006-06-01

    Differences in the oxidative stability of milk from cows fed grass-clover silage or hay were examined in relation to fatty acid composition and contents of antioxidants and copper in the milk. The oxidation processes were induced by exposing the milk to fluorescent light. Protein oxidation was measured as an accumulation of dityrosine, whereas lipid oxidation was measured as an accumulation of lipid hydroperoxides as the primary oxidation product, and as the secondary oxidation products, pentanal, hexanal, and heptanal. No differences were found in the protein oxidation of the 2 types of milk measured as accumulation of dityrosine, but there was an increased accumulation of lipid hydroperoxides and hexanal in milk from cows fed grass-clover silage, compared with milk from cows fed hay. The higher degree of lipid oxidation in milk from cows fed grass-clover silage could not be explained from the concentration of alpha-tocopherol, carotenoids, uric acid, and copper in the milk. However, it was thought to be highly influenced by the significantly higher concentration of linolenic acid present in milk from cows fed grass-clover silage. A larger part of alpha-tocopherol and beta-carotene was transferred from the feed to the milk when cows were fed grass-clover silage than when cows were fed hay as roughage. The significantly higher concentration of polyunsaturated fatty acids in milk from cows fed grass-clover silage may be important for the better transfer of alpha-tocopherol from the feed to the milk. Other circumstances, as the different conditions in the rumen may also play a role, due to the different types of roughages and their digestibility, or be related to the mechanisms during milk production for the higher yielding cows fed grass-clover silage. PMID:16702260

  8. Milk and other dietary influences on coronary heart disease

    NASA Technical Reports Server (NTRS)

    Grant, W. B.

    1998-01-01

    While dietary links to ischemic heart disease (IHD) and coronary heart disease (CHD) mortality have been studied for many years, the correlation has not clearly been resolved, especially for older populations. In this paper, a multi-country statistical approach involving 32 countries is used to find dietary links to IHD and CHD for various age groups aged 35+. For IHD, milk carbohydrates were found to have the highest statistical association for males aged 35+ and females aged 65+, while for females aged 35-64, sugar was found to have the highest association. In the case of CHD, non-fat milk was found to have the highest association for males aged 45+ and females aged 75+, while for females 65-74, milk carbohydrates and sugar had the highest associations, and for females aged 45-64, sugar had the highest association. A number of mechanisms have been proposed in the literature that might explain the milk carbohydrate or non-fat milk association. One of the most prominent theories is that animal proteins contribute to homocysteine (Hcy) production; however, milk more than meat lacks adequate B vitamins to convert Hcy to useful products. Lactose and calcium in conjunction with Hcy from consumption of non-fat milk may also contribute to calcification of the arteries.

  9. Longitudinal Study of Cytokine Expression, Lipid Profile and Neuronal Growth Factors in Human Breast Milk from Term and Preterm Deliveries

    PubMed Central

    Collado, Maria Carmen; Santaella, Marina; Mira-Pascual, Laia; Martínez-Arias, Elena; Khodayar-Pardo, Parisá; Ros, Gaspar; Martínez-Costa, Cecilia

    2015-01-01

    Breast milk (BM) is considered as a reference for infant nutrition. The role of bioactive components, such as cytokines, hormones, growth factors (GFs) and fatty acids (FAs) is poorly known, but they might be implicated in immune response development. The aim of this study was to identify the lipid profile and the spectrum of cytokines and neuronal GF in BM samples and analyse the influence of gestational age and lactation time on these components. This study used a longitudinal prospective method for the characterization of cytokines, FAs and GFs global profiles in 120 BM samples from 40 healthy mothers (20 preterm and 20 term) collected as colostrum, transitional and mature milk. The cytokines were analysed by protein array (Ray Bio® Human Cytokine Array G6. Ray Biotech, Inc. Norcross, GA, USA) and the FAs were analysed by gas chromatography. The FA profile was similar between the term and the preterm BM samples. Omega-3-α-linoleic and docosahexaenoic acid (DHA) and omega-6-linoleic acid were the most abundant in the term and preterm samples during lactation. Omega-3 ETA and omega-3 EPA we observed exclusively in the preterm samples. The cytokine profile showed a different trend based on gestational age. A significantly higher expression of neurotrophic factors was found in the mature preterm milk samples as compared to the mature term samples. Our study is the first to identify the influence and interactions of perinatal factors on cytokine, GFs and FAs in human milk. PMID:26492267

  10. Longitudinal Study of Cytokine Expression, Lipid Profile and Neuronal Growth Factors in Human Breast Milk from Term and Preterm Deliveries.

    PubMed

    Collado, Maria Carmen; Santaella, Marina; Mira-Pascual, Laia; Martínez-Arias, Elena; Khodayar-Pardo, Parisá; Ros, Gaspar; Martínez-Costa, Cecilia

    2015-10-01

    Breast milk (BM) is considered as a reference for infant nutrition. The role of bioactive components, such as cytokines, hormones, growth factors (GFs) and fatty acids (FAs) is poorly known, but they might be implicated in immune response development. The aim of this study was to identify the lipid profile and the spectrum of cytokines and neuronal GF in BM samples and analyse the influence of gestational age and lactation time on these components. This study used a longitudinal prospective method for the characterization of cytokines, FAs and GFs global profiles in 120 BM samples from 40 healthy mothers (20 preterm and 20 term) collected as colostrum, transitional and mature milk. The cytokines were analysed by protein array (Ray Bio® Human Cytokine Array G6. Ray Biotech, Inc. Norcross, GA, USA) and the FAs were analysed by gas chromatography. The FA profile was similar between the term and the preterm BM samples. Omega-3-α-linoleic and docosahexaenoic acid (DHA) and omega-6-linoleic acid were the most abundant in the term and preterm samples during lactation. Omega-3 ETA and omega-3 EPA we observed exclusively in the preterm samples. The cytokine profile showed a different trend based on gestational age. A significantly higher expression of neurotrophic factors was found in the mature preterm milk samples as compared to the mature term samples. Our study is the first to identify the influence and interactions of perinatal factors on cytokine, GFs and FAs in human milk. PMID:26492267

  11. Prelacteal feeding: influencing factors and relation to establishment of lactation.

    PubMed

    Ahmed, F U; Rahman, M E; Alam, M S

    1996-08-01

    This study was carried out with a view to finding out factors influencing prelacteal feeding and its relation to establishment of lactation in rural Bangladesh. 420 mothers in early post-partum period were interviewed at home. Prelacteal feeding was given to 77% of the babies, and honey was given to 72% of them. The common methods of prelacteal feeding were by finger (41%) and spoon (40%). Twelve socio-demographic and health care variables were studied for their probable influence on prelacteal feeding. Nine of them accounted for 22% of the variability in giving prelacteal feeding. Reasons of giving prelacteal feeding and the time of first breast feeding influenced the practice significantly (P < 0.05). Type and duration of prelacteal feeding had significant negative influence on "coming in" of milk (P < 0.05). Prelacteal feeding accounted for 44% of variations in coming in of milk. Prelacteal feeding and coming in of milk formed a vicious cycle: the former delayed initiation of lactation and on the other hand delay in coming in of milk encouraged prelacteal feeding. These observation emphasized the need for coordinated efforts for promotion of proper infant feeding practices in our rural community. PMID:9103657

  12. Transgenic pigs produce functional human factor VIII in milk.

    PubMed

    Paleyanda, R K; Velander, W H; Lee, T K; Scandella, D H; Gwazdauskas, F C; Knight, J W; Hoyer, L W; Drohan, W N; Lubon, H

    1997-10-01

    Deficiency or abnormality of coagulation factor VIII (FVIII) causes a bleeding disorder called hemophilia A. Treatment involves FVIII concentrates prepared from pooled human plasma or recombinant FVIII (rFVIII) prepared from mammalian cell culture. The cost of highly purified FVIII or rFVIII is a major factor in hemophilia therapy and restricts prophylaxis. We have sought to generate a new source of rFVIII by targeting expression of the human FVIII cDNA to the mammary gland of transgenic pigs using the regulatory sequences of the mouse whey acidic protein gene. The identity of processed heterodimeric rFVIII was confirmed using specific antibodies, by thrombin digestion and activity assays. The secretion of as much as 2.7 micrograms/ml of rFVIII in milk was over tenfold higher than in normal plasma. Up to 0.62 U/ml of rFVIII was detected in an assay in which rFVIII restored normal clotting activity to FVIII-deficient human plasma. PMID:9335047

  13. Phonological Awareness: Factors of Influence

    ERIC Educational Resources Information Center

    Frohlich, Linda Paulina; Petermann, Franz; Metz, Dorothee

    2013-01-01

    Early child development is influenced by various genetic and environmental factors. This study aims to identify factors that affect the phonological awareness of preschool and first grade children. Based on a sample of 330 German-speaking children (mean age = 6.2 years) the following domains were evaluated: Parent factors, birth and pregnancy,…

  14. Influence of milk production potential on forage dry matter intake by multiparous and primiparous Brangus females.

    PubMed

    Johnson, C R; Lalman, D L; Brown, M A; Appeddu, L A; Buchanan, D S; Wettemann, R P

    2003-07-01

    Brangus cows (n = 29) were used in three experiments to evaluate the effects of parity (multiparous vs. primiparous) and potential genetic merit for milk production (high vs. low) on forage intake during late gestation, early lactation, and late lactation. Cows were selected for milk production based on their sire's EPD for milk production (MEPD). Cows had ad libitum access to (130% of previous 2-d average intake) low-quality hay (5.3% CP and 76% NDF), and cottonseed meal was supplemented to ensure adequate degradable intake protein. All females were adapted to diets for at least 7 d, and individual intake data were collected for 9 d. During the lactation trials, actual milk production was determined using a portable milking machine following a 12-h separation from calves. During late gestation, multiparous cows consumed 24% more (P = 0.01) forage DM (kg/d) than primiparous cows; however, parity class did not influence forage intake when intake was expressed relative to BW. Furthermore, MEPD did not influence forage intake during late gestation. During early lactation, multiparous cows produced 66% more (P < 0.001) milk than primiparous cows, and high MEPD tended (P = 0.10) to produce more milk than low MEPD. Multiparous cows consumed 19% more (P < 0.0001) forage DM than did primiparous cows when expressed on an absolute basis, but not when expressed on a BW basis. High-MEPD cows consumed 8% more (P < 0.05) forage DM than did low-MEPD cows. During late lactation, multiparous cows produced 84% more milk than primiparous cows, although MEPD did not influence (P = 0.40) milk yield. In addition, multiparous cows consumed 17% more (P < 0.01) forage DM per day than primiparous cows, but when intake was expressed relative to BW, neither parity nor MEPD influenced forage DMI during late lactation. Milk yield and BW explained significant proportions of the variation in forage DMI during early and late lactation. Each kilogram increase in milk yield was associated with a 0

  15. The influence of impact delivery mode, lactation time, infant gender, maternal age and rural or urban life on total number of Lactobacillus in breast milk Isfahan - Iran

    PubMed Central

    Taghizadeh, Mansoureh; Mirlohi, Maryam; Poursina, Farkhondeh; Madani, Golnoush; Khoshhali, Mehri; Bahreini, Nimah; Safaei, Hajieh Ghasemian

    2015-01-01

    Background: Breast milk is known as the most crucial postpartum issue in metabolic and immunologic programming of neonatal health. Human milk microbial changes over Lactation. The factors influencing the milk microbiome as well as potential impact of microbes on infant health have not yet been discovered. The objective was to identify pre- and post-natal factors that can potentially influence the bacterial communities inhabiting human milk. Materials and Methods: Breast milk samples (n = 40) with all full-term breastfed infants were collected from lactating randomized. Information on personal characteristics, dietary habits, information about infants were collected after birth. The samples were plated with serial dilutions on three selective culture media man rogosa sharp and then colonies were counted. Colonies tested for catalase reaction, Gram-staining and microscopic examination. Results: The result of this study showed that the overall incidence of positive Lactobacillus in mother's milk was 87.5%. The results based on (infant gender, mode of delivery, rural or urban and lactation time) rural or urban and lactation time were significant (P < 0.05). The results showed that all of the variables were significant in this regression model (P < 0.001). The median of log10 Lactobacillus counts in rural mothers, vaginal delivery, infant male gender and Lactation time for first 3-month were meaningfully high. Conclusions: The findings of this study about the breast milk Lactobacillus potential probiotic bacteria of healthy Iranian mothers, suggested that the breast milk microbiome is significantly influenced by several factors, mode of delivery, rural or urban and lactation time. PMID:26322289

  16. Influence of micellar calcium and phosphorus on rennet coagulation properties of cows milk.

    PubMed

    Malacarne, Massimo; Franceschi, Piero; Formaggioni, Paolo; Sandri, Sandro; Mariani, Primo; Summer, Andrea

    2014-05-01

    The main requirement for milk processed in most cheese typologies is its rennet coagulation ability. Despite the increasing number of studies, the causes for abnormal coagulation of milk are not fully understood. The aim of this study was to ascertain relationships between milk characteristics and its rennet coagulation ability, focusing on the influence of calcium (Ca) and phosphorus (P). Ca and P are essential constituents of the micelles. Micellar P can be present as part of colloidal calcium phosphate (inorganic-P) or covalently bound to caseins as phosphate groups (casein-P). Eighty one herd milk samples (SCC<400 000 cell/ml) were classified as Optimal (8), Suboptimal (39) Poor (29) and Non-coagulating milk (5), according to their rennet coagulation parameters as assessed by lactodynamographic test. Samples were analysed for their chemical composition (basic composition, protein fractions, minerals and salt equilibria), physicochemical parameters (pH and titratable acidity) and rheological properties. Optimal milk was characterised by the highest contents of major constituents, protein fractions and minerals, lowest content of chloride and highest values of titratable acidity. Non-coagulating milk was characterised by the highest values of pH and the lowest of titratable acidity. At micellar level, Optimal milk showed the highest values of colloidal Ca, casein-P and colloidal Mg (g/100 g casein), while Non-coagulating milk showed the lowest values. Interestingly, there was no statistical difference regarding the content of colloidal inorganic-P (g/100 g casein) between Optimal and Non-coagulating milks. Overall, high mineralisation of the micelle (expressed as g inorganic-P/100 g casein) positively affect its rennetability. However, excessive mineralisation could lead to a reduction of the phosphate groups (g casein-P/100 g casein) available for curd formation. PMID:24345431

  17. Evidence of terroir in milk sourcing and its influence on Cheddar cheese.

    PubMed

    Turbes, Gregory; Linscott, Tyler D; Tomasino, Elizabeth; Waite-Cusic, Joy; Lim, Juyun; Meunier-Goddik, Lisbeth

    2016-07-01

    The concept of local food is rapidly gaining importance within the United States. The foundation of local food is terroir, which links a food to its production environment. The purpose of this study was to investigate evidence of terroir in milk sourcing and its influence on Cheddar cheese flavor. Specifically, the study was designed to assess if consumers could differentiate between Cheddar cheeses made with milk from different dairy farms. Milk from 5 locations, including single dairy farms and commingled sites, was collected from around the state of Oregon. Using raw and pasteurized counterparts of the milk, Cheddar cheese was made and aged. At 5 and 9mo into aging, Cheddar cheese consumers were asked to group the samples based on perceived similarity/dissimilarity of cheese flavor. Grouping data were subjected to multidimensional scaling and subsequent cluster analysis. Results at 5mo into aging revealed that cheeses made by milk originating from different farms (80km apart) within the same region were perceived as different, whereas cheeses made with milk from neighboring farms (5km apart) were grouped together, irrespective of heat treatment (i.e., raw vs. pasteurized). Cheeses made with commingled milk from different regions grouped together. At 9mo of aging, in contrast, a clear separation of perceived flavor was present between the pasteurized and raw cheese samples, whereas the effect of milk sourcing was less pronounced. These data suggest that the geographical location of the milk source has an effect on the flavor of Cheddar cheese, but that the practices of milk commingling and heat treatment likely reduce the effect of geographical location, particularly as cheese ages. PMID:27085404

  18. Impact of the removal of chocolate milk from school milk programs for children in Saskatoon, Canada.

    PubMed

    Henry, Carol; Whiting, Susan J; Phillips, Theodosia; Finch, Sarah L; Zello, Gordon A; Vatanparast, Hassan

    2015-03-01

    Studies in the United States report inclusion of flavoured milk in the diets of children and youth improves nutrient intakes. No research has investigated the contribution of flavoured milk to overall milk intake or the milk preferences of Canadian children. The objective of the study was to measure milk consumption (plain milk and flavoured milk) by children in an elementary school environment and investigate factors contributing to milk choice. A mixed-method research design was applied across 6 schools for 12 weeks. Milk waste was measured in grades 1-8 for 12 weeks. Weeks 1-4 (phase 1) and 9-12 (phase 3) provided both plain milk and flavoured milk as chocolate milk while weeks 5-8 (phase 2) provided plain milk only. Beverage Frequency Questionnaires were used in each phase (in grades 5-8 only) to assess usual beverage consumption. Statistical nutrient modelling was conducted to determine the effects of removing chocolate milk during phase 2 as a milk choice. Later, focus groups were conducted with students in grades 5-8 to determine what influences them to choose/not choose to drink milk. Total milk intake decreased by 12.3% when chocolate milk was removed from the schools (26.6% ± 5.2% to 14.31% ± 1.6%, p < 0.001). Milk choice was influenced by environmental factors as well as taste, cost, convenience, and variety. Total milk intake was associated with location (p = 0.035) and cost (p < 0.001), with rural students and/or those students receiving free milk drinking the greatest amount of milk. Nutrient modelling revealed chocolate milk is more cost-efficient and convenient at providing nutrients than alternative food/drink combinations. PMID:25585706

  19. Factors That Influence Teacher Attrition.

    ERIC Educational Resources Information Center

    Gonzalez, Patricia

    1995-01-01

    External, employment, and personal factors which influence teacher decisions to stay, leave, or transfer from teaching assignments are discussed, with emphasis on special education teachers. Factors attributed to teacher attrition in urban and rural environments also are briefly reviewed, along with attrition of related services professionals.…

  20. Food safety in raw milk production: risk factors associated to bacterial DNA contamination.

    PubMed

    Cerva, Cristine; Bremm, Carolina; Reis, Emily Marques dos; Bezerra, André Vinícius Andrade; Loiko, Márcia Regina; Cruz, Cláudio Estêvão Farias da; Cenci, Alexander; Mayer, Fabiana Quoos

    2014-06-01

    While human illness from milkborne pathogens may be linked to contamination of the product after pasteurization or improper pasteurization, such diseases are usually associated with consumption of raw milk or its by-products. Molecular biology tools were applied to investigate contamination by Listeria monocytogenes, Salmonella spp., some pathogenic strains of Escherichia coli, and Campylobacter jejuni in 548 raw milk samples from 125 dairy farms established in two regions from southern Brazil. Moreover, 15 variables were evaluated for their association with raw milk contamination levels, and the risk factors were determined by multiple regression analysis. Salmonella spp. were more frequently detected, followed by pathogenic E. coli. There was difference in contamination index between the regions, in which risk factors such as temporary cattle confinement, low milk production, low milking machine cleaning frequency, and milk storage area without tile walls were identified. The risk factors were specific to each region studied. Nevertheless, the data can be used to improve milk quality of dairy farms/herds with similar management practices. PMID:24715203

  1. Factors influencing dental decision making.

    PubMed

    Grembowski, D; Milgrom, P; Fiset, L

    1988-01-01

    In clinical decision making, dentists routinely choose between alternative treatments such as crown vs amalgam/composite buildup, root canal vs extraction, fixed bridge vs removable partial denture, and prophylaxis vs subgingival curettage or periodontal scaling. A number of technical and patient factors can influence dentists' choice of treatment in these situations; however, little is known about their relative importance. To address this issue, a list of technical (e.g., periodontal status and caries rate) and patient (e.g., cost and patient preference) factors possibly influencing choice of treatment was developed for each pair of services. Responding to a mail questionnaire, 156 general dentists in Washington State listed the top three factors influencing their choice of service in each pair. Results revealed that dentists took different factors into account in choosing among alternative treatments. Technical factors dominated over patient concerns; only about 33 percent of the dentists considered patient factors important in choosing alternative therapies. The latter group was less preventively oriented, were solo practitioners, worked longer hours, and had lower prices. Results suggest patients may have little influence on prescriptions of therapy among experienced general dentists. PMID:3045303

  2. Risk factors affecting chemical and bacteriological quality of bulk tank milk in Kerman, Iran

    PubMed Central

    Mansouri-Najand, Ladan; Rezaii, Zeinab

    2015-01-01

    Milk is often described as a complete food because it contains protein, sugar, fat, vitamins, and minerals. This study was performed to investigate risk factors affecting chemical and bacteriological quality of bulk tank milk. According to the following conducted experiments, the milk was divided into two standard and non-standard groups. Then, effect of risk factors on making the samples non-standard was studied. Risk factors such as type of milk delivery unit, distance of cattle farm from plant, size of herd, education level of stockbreeders, capacity of milk transport tank, capacity of cooler device, and number of workers employed in cattle farms were evaluated in this study. Microbial and chemical evaluations were performed. Beta-lactam antibiotic residues and somatic cell count were specified. At the same time, the stockbreeders who referred to the plant were given some questionnaires and the mentioned primary questions were asked. After collecting the data, logistic regression model was used. According to the obtained results and comparison with Iran’s national standard, 26 out of 109 samples were determined to be at standard level and 83 ones had at least one out-of-standard factor. The results obtained from the model demonstrated significant effect of education of stockbreeders and capacity of cooler devices on the milk quality. Education of stockbreeders could greatly affect management of a cattle farm unit. PMID:25992256

  3. Factors Influencing College Science Success

    ERIC Educational Resources Information Center

    Tai, Robert H.; Sadler, Philip M.; Mintzes, Joel J.

    2006-01-01

    In this paper, the authors report some of the salient findings of a large-scale, four-year national study, conducted at the Harvard-Smithsonian Center for Astrophysics, entitled "Factors Influencing College Science Success" (FICSS), which surveyed college students who enrolled in first-year biology, chemistry, and physics courses throughout the…

  4. Soft Factors Influence College Enrollment

    ERIC Educational Resources Information Center

    Fogg, Neeta P.; Harrington, Paul E.

    2010-01-01

    Evidence about the role that "soft factors" like student engagement and school environment play in influencing whether high school students go on to enroll in college is hard to come by. Over the past two years, the Center for Labor Market Studies (CLMS) of Northeastern University, with support from the Nellie Mae Education Foundation and the…

  5. Influence of fructooligosaccharides on the fermentation profile and viable counts in a symbiotic low fat milk

    PubMed Central

    Oliveira, Ricardo P.S.; Casazza, Alessandro A.; Aliakbarian, Bahar; Perego, Patrizia; Converti, Attilio; Oliveira, Maricê N.

    2013-01-01

    This study evaluated the effects of prebiotics on fermentation profile and growth of Lactobacillus acidophilus, Lactobacillus bulgaricus, Lactobacillus rhamnosus, and Bifidobacterium lactis in co-cultures with Streptococcus thermophilus. Acidification rate and viability were positively influenced by the co-culture with B. lactis and by both inulin or oligofructose in low fat milk. PMID:24294233

  6. Influence of fructooligosaccharides on the fermentation profile and viable counts in a symbiotic low fat milk.

    PubMed

    Oliveira, Ricardo P S; Casazza, Alessandro A; Aliakbarian, Bahar; Perego, Patrizia; Converti, Attilio; Oliveira, Maricê N

    2013-01-01

    This study evaluated the effects of prebiotics on fermentation profile and growth of Lactobacillus acidophilus, Lactobacillus bulgaricus, Lactobacillus rhamnosus, and Bifidobacterium lactis in co-cultures with Streptococcus thermophilus. Acidification rate and viability were positively influenced by the co-culture with B. lactis and by both inulin or oligofructose in low fat milk. PMID:24294233

  7. Transference factors as a tool for the estimation of arsenic milk concentration.

    PubMed

    Pérez-Carrera, Alejo; Alvarez-Gonçalvez, Cristina V; Fernández-Cirelli, Alicia

    2016-08-01

    The Chaco Pampean Plain of central Argentina represents one of the largest regions with high levels of arsenic (As) in groundwater. The aim of this study was the assessment of a biotransference factor (BTF) as a tool for the estimation of As concentration in cow's milk from As drinking water concentration. Total As content in livestock drinking water, soil, forage, and milk was determined in farms located in an area of high As groundwater, in order to analyze the relation between As uptake and its transfer to milk. The concentrations of As in milk ranged from 0.5 to 8.0 μg/L. From the results obtained, drinking water may be considered the main source of exposure to As, and the biotransference factor for milk ranges from 1.5 × 10(-5) to 4.3 × 10(-4). Therefore, BTF provides a simple tool for the estimation of arsenic levels in milk through the As livestock drinking water content. PMID:27155835

  8. Factors influencing pacing in triathlon

    PubMed Central

    Wu, Sam SX; Peiffer, Jeremiah J; Brisswalter, Jeanick; Nosaka, Kazunori; Abbiss, Chris R

    2014-01-01

    Triathlon is a multisport event consisting of sequential swim, cycle, and run disciplines performed over a variety of distances. This complex and unique sport requires athletes to appropriately distribute their speed or energy expenditure (ie, pacing) within each discipline as well as over the entire event. As with most physical activity, the regulation of pacing in triathlon may be influenced by a multitude of intrinsic and extrinsic factors. The majority of current research focuses mainly on the Olympic distance, whilst much less literature is available on other triathlon distances such as the sprint, half-Ironman, and Ironman distances. Furthermore, little is understood regarding the specific physiological, environmental, and interdisciplinary effects on pacing. Therefore, this article discusses the pacing strategies observed in triathlon across different distances, and elucidates the possible factors influencing pacing within the three specific disciplines of a triathlon. PMID:25258562

  9. Feeding goats on scrubby Mexican rangeland and pasteurization: influences on milk and artisan cheese quality

    PubMed Central

    Hilario, Mario Cuchillo; Wrage, Nicole; Pérez-Gil R., Fernando

    2010-01-01

    The objective of this study was to evaluate the effect of foraging on local scrubby rangeland versus stable feeding with high-protein concentrate as well as the compulsory pasteurization process on goats’ milk and artisan soft cheese quality in terms of chemical composition and fatty acid profile. The results indicated that there were no significant differences in the energy, fat, or ash content of milk and cheese due to feeding; however, a significant influence of feeding on cheese protein and fatty acids in both milk and cheese was detected. Feeding on scrubby rangeland tended to increase the amounts of major polyunsaturated fatty acids in milk and cheese from goats. Pasteurization, which is mandatory in Mexico, did not alter the fatty acid concentrations in milk or cheese. Small goat-keepers using rangeland resources might claim better economical returns for products recognized as healthier. Further investigations to assure ecosystem sustainability of shrubby rangeland joined with economical evaluations and best animal management to avoid deleterious effects are recommended. PMID:20229357

  10. Choline intake and genetic polymorphisms influence choline metabolite concentrations in human breast milk and plasma123

    PubMed Central

    Fischer, Leslie M; da Costa, Kerry Ann; Galanko, Joseph; Sha, Wei; Stephenson, Brigitte; Vick, Julie; Zeisel, Steven H

    2010-01-01

    Background: Choline is essential for infant nutrition, and breast milk is a rich source of this nutrient. Common single nucleotide polymorphisms (SNPs) change dietary requirements for choline intake. Objective: The aim of this study was to determine whether total choline intake and/or SNPs influence concentrations of choline and its metabolites in human breast milk and plasma. Design: We gave a total of 103 pregnant women supplemental choline or a placebo from 18 wk gestation to 45 d postpartum and genotyped the women for 370 common SNPs. At 45 d postpartum, we measured choline metabolite concentrations in breast milk and plasma and assessed the dietary intake of choline by using a 3-d food record. Results: On average, lactating women in our study ate two-thirds of the recommended intake for choline (Adequate Intake = 550 mg choline/d). Dietary choline intake (no supplement) correlated with breast-milk phosphatidylcholine and plasma choline concentrations. A supplement further increased breast-milk choline, betaine, and phosphocholine concentrations and increased plasma choline and betaine concentrations. We identified 5 SNPs in MTHFR that altered the slope of the intake–metabolite concentration relations, and we identified 2 SNPs in PEMT that shifted these curves upward. Individuals who shared sets of common SNPs were outliers in plots of intake–metabolite concentration curves; we suggest that these SNPs should be further investigated to determine how they alter choline metabolism. Conclusion: Total intake of choline and genotype can influence the concentrations of choline and its metabolites in the breast milk and blood of lactating women and thereby affect the amount of choline available to the developing infant. This study was registered at clinicaltrials.gov as NCT00678925. PMID:20534746

  11. The consumption of flavored milk among a children population. The influence of beliefs and the association of brands with emotions.

    PubMed

    De Pelsmaeker, Sara; Schouteten, Joachim; Gellynck, Xavier

    2013-12-01

    Although milk and dairy products are seen as an important part of a child's diet, their consumption is declining. The aim of this study is to investigate the consumption of milk and flavored milk among a sample of 513 Belgian children aged between 8 and 13 years. In addition, the association between flavored milk brands and emotions is examined. Children prefer and consume more flavored than plain milk. They indicate that consumption is a self-made choice and that parents mainly ensure the availability of these products. Children prefer flavored milk to plain milk, although it is perceived to be less healthy. No correlation could be found between brand awareness and the consumption of flavored milk. Brands of flavored milk evoke divergent emotions and can be classified into different groups based upon their association with a type of emotion (i.e. positive/negative). This study demonstrates that taste is an important factor in flavored milk consumption by children and shows a strong relationship between brands and emotions. Consequently, the taste needs to be appealing for children, but it is equally important that children associate the brand with positive emotions, as this will lead to a higher preference. Milk producers who target children can use the insights gained from this study in the development of new products. PMID:24001396

  12. Risk factors for bulk milk somatic cell counts and total bacterial counts in smallholder dairy farms in the 10th region of Chile.

    PubMed

    van Schaik, G; Green, L E; Guzmán, D; Esparza, H; Tadich, N

    2005-01-01

    We investigated the principal management factors that influenced bulk milk somatic cell count (BMSCC) and total bacterial count (TBC) of smallholder dairy farms in the 10th region of Chile. One hundred and fifty smallholder milk producers were selected randomly from 42 milk collection centres (MCCs). In April and May of 2002, all farms were visited and a detailed interview questionnaire on dairy-cow management related to milk quality was conducted. In addition, the BMSCC and TBC results from the previous 2 months' fortnightly tests were obtained from the MCCs. The mean BMSCC and TBC were used as the dependent variables in the analyses and were normalised by a natural-logarithm transformation (LN). All independent management variables were categorised into binary outcomes and present (=1) was compared with absent (=0). Biserial correlations were calculated between the LNBMSCC or LNTBC and the management factors of the smallholder farms. Management factors with correlations with P0.05) factors. A random MCC effect was included in the models to investigate the importance of clustering of herds within MCC. In the null model for mean LNTBC, the random effect of MCCs was highly significant. It was explained by: milk collected once a day or less compared with collection twice a day, not cleaning the bucket after milking mastitic cows versus cleaning the bucket and cooling milk in a vat of water versus not cooling milk or using ice or a bulk tank to cool milk. Other factors that increased the LNTBC were a waiting yard with a soil or gravel floor versus concrete, use of plastic buckets for milking instead of metal, not feeding California mastitis test (CMT)-positive milk to calves and cows of dual-purpose breed. The final model explained 35% of the variance. The model predicted that a herd that complied with all the management practices had a mean

  13. Influences of season, parity, lactation, udder area, milk yield, and clinical symptoms on intramammary infection in dairy cows.

    PubMed

    Zhang, Z; Li, X P; Yang, F; Luo, J Y; Wang, X R; Liu, L H; Li, H S

    2016-08-01

    The aim of this study was to evaluate the influences of season, parity, lactation, udder area, milk yield, and clinical symptoms on bacterial intramammary infection (IMI) in dairy cows. A total of 2,106 mastitis pathogens in 12 species were isolated from 125 dairy farms distributed in 30 different cities in China, and the information about these factors was recorded at the same time. Mastitis pathogens were isolated from 63.43% of the milk samples, whereas Streptococcus agalactiae accounted for 38.61% of all pathogens, followed by Str. dysgalactiae (28.16%), Staphylococcus aureus (19.10%), Escherichia coli (6.90%), and other pathogens (7.23%). According to our investigation, IMI was more common in spring with the isolation rate of pathogens at 81.04%, and lowest in winter (52.34%). Cows were more likely to be infected by environmental pathogens (E. coli or Str. uberis) in summer, in rear quarters and in cows with higher daily milk yield or lower somatic cell count. In addition, Str. dysgalactiae exhibited a higher prevalence with increased parity. Different clinical symptoms of quarters with bacterial IMI were seen in this study, and mastitis pathogens were isolated from healthy quarters. PMID:27265170

  14. Milk Consumption and Cardiovascular Risk Factors in Older Chinese: The Guangzhou Biobank Cohort Study

    PubMed Central

    Sun, Yangbo; Jiang, Chaoqiang; Cheng, Kar Keung; Zhang, Weisen; Leung, Gabriel M.; Lam, Tai Hing; Schooling, C. Mary

    2014-01-01

    Background Dairy products consumption is increasingly common globally. Most of the evidence concerning dairy products comes from observational studies in western populations which are inevitably open to confounding. To triangulate the evidence concerning dairy products, we examined the associations of whole cow's milk consumption with cardiovascular risk factors in a non-Western setting with a different pattern of milk consumption and cardiovascular diseases from Western populations. Methods We used multivariable censored linear or logistic regression to examine cross-sectionally the adjusted associations of whole cow's milk consumption (none (n = 14892), 1–3/week (n = 2689) and 3+/week (n = 2754)) with cardiovascular risk factors in Chinese (≥50 years) in the Guangzhou Biobank Cohort Study. Results Whole cow's milk consumption was negatively associated with systolic blood pressure (3+/week compared to none −2.56 mmHg, 95% confidence interval (CI) −3.63 to −1.49), diastolic blood pressure (−1.32 mmHg, 95% CI −1.87 to −0.77) and triglycerides (−0.06 mmol/L, 95% CI −0.11 to −0.002), but was positively associated with HDL-cholesterol (0.02 mmol/L,95% CI 0.01 to 0.04) and fasting glucose (0.08 mmol/L, 95% CI 0.01 to 0.16) adjusted for age, sex, phase of study, socio-economic position, lifestyle (smoking, alcohol use and physical activity) and adiposity, but had no obvious association with LDL-cholesterol or the presence of diabetes. Conclusions Whole cow's milk consumption had heterogeneous associations with cardiovascular risk factors. Higher whole cow's milk consumption was associated with lower levels of specific cardiovascular risk factors which might suggest risk factor specific biological pathways with different relations to blood pressure and lipids than glucose. PMID:24416290

  15. Human Milk Oligosaccharides in Premature Infants: Absorption, Excretion and Influence on the Intestinal Microbiota

    PubMed Central

    Underwood, Mark A.; Gaerlan, Stephanie; De Leoz, M. Lorna A.; Dimapasoc, Lauren; Kalanetra, Karen M.; Lemay, Danielle G.; German, J. Bruce; Mills, David A.; Lebrilla, Carlito B.

    2015-01-01

    Background Human milk oligosaccharides (HMOs) shape the intestinal microbiota in term infants. In premature infants, alterations in the intestinal microbiota (dysbiosis) are associated with risk of necrotizing enterocolitis and sepsis and the influence of HMOs on the microbiota is unclear. Methods Milk, urine, and stool specimens from 14 mother-premature infant dyads were investigated by mass spectrometry for HMO composition. The stools were analyzed by next-generation sequencing (NGS) to complement a previous analysis. Results Percentages of fucosylated and sialylated HMOs were highly variable between individuals but similar in urine, feces and milk within dyads. Differences in urine and fecal HMO composition suggest variability in absorption. Secretor status of the mother correlated with the urine and fecal content of specific HMO structures. Trends toward higher levels of Proteobacteria and lower levels of Firmicutes, were noted in premature infants of non-secretor mothers. Specific HMO structures in the milk, urine and feces were associated with alterations in fecal Proteobacteria and Firmicutes. Conclusion HMOs may influence the intestinal microbiota in premature infants. Specific HMOs, for example those associated with secretor mothers, may have a protective effect by decreasing pathogens associated with sepsis and necrotizing enterocolitis while other HMOs may increase dysbiosis in this population. PMID:26322410

  16. Influence of prematurity and birth weight on the concentration of α-tocopherol in colostrum milk

    PubMed Central

    Grilo, Evellyn Câmara; de Lira, Larissa Queiroz; Dimenstein, Roberto; Ribeiro, Karla Danielly da S.

    2013-01-01

    OBJECTIVE: To assess vitamin E levels in the breast milk, analyzing the prematurity and the birth weight influence in α-tocopherol concentration of colostrum milk. METHODS: Cross-sectional study, in which the colostrum was collected from 93 nursing mothers in a public maternity of Natal, Rio Grande do Norte, Northeast Brazil. The newborns were classified based on gestational age and birth weight. The analysis of α-tocopherol in the milk was carried out by high performance liquid chromatography. RESULTS: The α-tocopherol concentration in the colostrum of lactating women whose children were born at term was 1,093.6±532.4µg/dL; for preterm infants, the concentration was 1,321.6±708.5µg/dL (p=0.109). In the preterm group, the α-tocopherol concentration in the colostrum of lactating women whose children were born with low and normal birth weight was 1,316.0±790.7 and 1,327.2±655.0µg/dL, respectively (p=0.971). In the term group, the α-tocopherol levels were higher in mothers of children with birth weight >4000g, being 1,821.0±575.4µg/dL, compared to 869.5±532.1µg/dL and 1,039.6±477.5µg/dL with low and adequate birth weight, respectively (p>0.05). CONCLUSIONS: Prematurity did not influence α-tocopherol levels in the colostrum milk. Mothers who had macrossomic term neonates presented increased α-tocopherol levels. These results indicate that birth weight can influence α-tocopherol leves in the colostrum milk. PMID:24473952

  17. Effect of microfiltration concentration factor on serum protein removal from skim milk using spiral-wound polymeric membranes.

    PubMed

    Beckman, S L; Barbano, D M

    2013-10-01

    Our objective was to determine the effect of concentration factor (CF) on the removal of serum protein (SP) from skim milk during microfiltration (MF) at 50 °C using a 0.3-μm-pore-size spiral-wound (SW) polymeric polyvinylidene fluoride (PVDF) membrane. Pasteurized (72°C for 16 s) skim milk was MF (50 °C) at 3 CF (1.50, 2.25, and 3.00×), each on a separate day of processing starting with skim milk. Two phases of MF were used at each CF, with an initial startup-stabilization phase (40 min in full recycle mode) to achieve the desired CF, followed by a steady-state phase (90-min feed-and-bleed with recycle) where data was collected. The experiment was replicated 3 times, and SP removal from skim milk was quantified at each CF. System pressures, flow rates, CF, and fluxes were monitored during the 90-min run. Permeate flux increased (12.8, 15.3, and 19.0 kg/m(2) per hour) with decreasing CF from 3.00 to 1.50×, whereas fouled water flux did not differ among CF, indicating that the effect of membrane fouling on hydraulic resistance of the membrane was similar at all CF. However, the CF used when microfiltering skim milk (50°C) with a 0.3-μm polymeric SW PVDF membrane did affect the percentage of SP removed. As CF increased from 1.50 to 3.00×, the percentage of SP removed from skim milk increased from 10.56 to 35.57%, in a single stage bleed-and-feed MF system. Percentage SP removal from skim milk was lower than the theoretical value. Rejection of SP during MF of skim milk with SW PVDF membranes was caused by fouling of the membrane, not by the membrane itself and differences in the foulant characteristic among CF influenced SP rejection more than it influenced hydraulic resistance. We hypothesize that differences in the conditions near the surface of the membrane and within the pores during the first few minutes of processing, when casein micelles pass through the membrane, influenced the rejection of SP because more pore size narrowing and plugging occurred at

  18. Factors influencing healthcare service quality

    PubMed Central

    Mosadeghrad, Ali Mohammad

    2014-01-01

    Background: The main purpose of this study was to identify factors that influence healthcare quality in the Iranian context. Methods: Exploratory in-depth individual and focus group interviews were conducted with 222 healthcare stakeholders including healthcare providers, managers, policy-makers, and payers to identify factors affecting the quality of healthcare services provided in Iranian healthcare organisations. Results: Quality in healthcare is a production of cooperation between the patient and the healthcare provider in a supportive environment. Personal factors of the provider and the patient, and factors pertaining to the healthcare organisation, healthcare system, and the broader environment affect healthcare service quality. Healthcare quality can be improved by supportive visionary leadership, proper planning, education and training, availability of resources, effective management of resources, employees and processes, and collaboration and cooperation among providers. Conclusion: This article contributes to healthcare theory and practice by developing a conceptual framework that provides policy-makers and managers a practical understanding of factors that affect healthcare service quality. PMID:25114946

  19. Evaluation of non-genetic factors affecting calf growth, reproductive performance and milk yield of traditionally managed Sheko cattle in southwest Ethiopia.

    PubMed

    Bayou, E; Haile, A; Gizaw, S; Mekasha, Y

    2015-01-01

    The study was conducted to estimate calf growth, reproductive performance and milk yield of Ethiopia Sheko cattle and to assess non-genetic factors affecting their performance in their home tract as a step towards designing sustainable cattle conservation and improvement strategy. All the growth traits considered in the study were significantly affected by all non-genetic factors considered except for the fixed effects of Agro ecological zones (AEZs) and season of birth which were not significant for post weaning daily gain. Calving interval (CI) and days open (DO) were significantly influenced by AEZs, season and dam parity. Cows that calved in lowland had shorter CI and DO than cows which calved in midland. Cows that calved in short rainy season had Short CI and DO than those calved during dry season or long rainy season. Cows which calved for the first time had the longest CI and DO from the other parities whereas cows on their fifth parity had the shortest CI and DO. AEZ significantly affected lactation milk yield (LMY) and lactation length (LL), but not significant on daily milk yield (DMY) and 305 days yield (305DY). Season was significant on all milk traits considered except DMY. Parity effect was significant on LMY and 305DY, whereas DMY and LL were not affected. The non-genetic factors had significant effects for all of the reproductive; and many of the growth and milk performance traits considered and hence will need to be considered in cattle breed improvement program. PMID:26543703

  20. Isolated milk fat globules as substrate for lipoprotein lipase: study of factors relevant to spontaneous lipolysis in milk

    SciTech Connect

    Sundheim, G.; Bengtsson-Olivecrona, G.

    1987-03-01

    Fat globules isolated from normal and from spontaneous milk samples were compared as substrates for purified lipoprotein lipase. Only slight differences were observed. Fat globules isolated from fresh warm milk were almost resistant to lipolysis. This included globules from milk prone to spontaneous lipolysis. Cooling made the globules accessible to rapid lipolysis even if they were from normal milk. Rewarming the fat globules did not reverse the process. Maximum rate of lipolysis (after rewarming) required fat globules be stored at 10/sup 0/C or below for 5 to 10 h. Lipolysis at 4/sup 0/C usually started after a lag time of 3 to 5 h, but with fat globules from spontaneous milk the lag time was shorter. Fat globules isolated from cold milk were a poor substrate at 4/sup 0/C but were lipolyzed when warmed. When /sup 125/I-labeled lipase was added to fresh warm milk, some of the lipase bound to the milk fat globules but it caused little lipolysis. Binding increased after cooling, as did lipolysis. Both binding of lipase and lipolysis were impeded by the presence of skim milk. Another way to make fat globules isolated from fresh warm milk susceptible to lipolysis was to treat them with chemicals known to remove proteins.

  1. Fermented goat milk consumption improves melatonin levels and influences positively the antioxidant status during nutritional ferropenic anemia recovery.

    PubMed

    Moreno-Fernandez, Jorge; Diaz-Castro, Javier; Alférez, M José M; Nestares, Teresa; Ochoa, Julio J; Sánchez-Alcover, Ana; López-Aliaga, Inmaculada

    2016-02-01

    The aim of the current study was to assess the influence of fermented goat or cow milk on melatonin levels and antioxidant status and during anemia recovery. Eighty male Wistar rats were placed on a pre-experimental period of 40 days and randomly divided into two groups, a control group receiving normal-Fe diet (45 mg kg(-1)) and the Fe-deficient group receiving low-Fe diet (5 mg kg(-1)). Then, the rats were fed with fermented goat or cow milk-based diets with a normal-Fe content or Fe-overload (450 mg kg(-1)) for 30 days. After 30 days of feeding the fermented milks, the total antioxidant status (TAS) was higher in both groups of animals fed fermented goat milk with the normal-Fe content. Plasma and urine 8-OHdG were lower in control and anemic rats fed fermented goat milk. Melatonin and corticosterone increased in the anemic groups during Fe replenishment with both fermented milks. Urine isoprostanes were lower in both groups fed fermented goat milk. Lipid and protein oxidative damage were higher in all tissues with fermented cow milk. During anemia instauration, an increase in melatonin was observed, a fact that would improve the energy metabolism and impaired inflammatory signaling, however, during anemia recovery, fermented goat milk had positive effects on melatonin and TAS, even in the case of Fe-overload, limiting the evoked oxidative damage. PMID:26662041

  2. Examining trust factors in online food risk information: The case of unpasteurized or 'raw' milk.

    PubMed

    Sillence, Elizabeth; Hardy, Claire; Medeiros, Lydia C; LeJeune, Jeffrey T

    2016-04-01

    The internet has become an increasingly important way of communicating with consumers about food risk information. However, relatively little is known about how consumers evaluate and come to trust the information they encounter online. Using the example of unpasteurized or raw milk this paper presents two studies exploring the trust factors associated with online information about the risks and benefits of raw milk consumption. In the first study, eye-tracking data was collected from 33 pasteurised milk consumers whilst they viewed six different milk related websites. A descriptive analysis of the eye-tracking data was conducted to explore viewing patterns. Reports revealed the importance of images as a way of capturing initial attention and foregrounding other features and highlighted the significance of introductory text within a homepage. In the second, qualitative study, 41 consumers, some of whom drank raw milk, viewed a selection of milk related websites before participating in either a group discussion or interview. Seventeen of the participants also took part in a follow up telephone interview 2 weeks later. The qualitative data supports the importance of good design whilst noting that balance, authorship agenda, the nature of evidence and personal relevance were also key factors affecting consumers trust judgements. The results of both studies provide support for a staged approach to online trust in which consumers engage in a more rapid, heuristic assessment of a site before moving on to a more in-depth evaluation of the information available. Findings are discussed in relation to the development of trustworthy online food safety resources. PMID:26792772

  3. Viral and immunological factors associated with breast milk transmission of SIV in rhesus macaques

    PubMed Central

    Amedee, Angela M; Rychert, Jenna; Lacour, Nedra; Fresh, Lynn; Ratterree, Marion

    2004-01-01

    Background The viral and host factors involved in transmission of HIV through breastfeeding are largely unknown, and intervention strategies are urgently needed to protect at-risk populations. To evaluate the viral and immunological factors directly related to milk transmission of virus, we have evaluated the disease course of Simian Immunodeficiency Virus (SIV) in lactating rhesus macaques (Macaca mulatta) as a model of natural breast milk transmission of HIV. Results Fourteen lactating macaques were infected intravenously with SIV/DeltaB670, a pathogenic isolate of SIV and were pair-housed with their suckling infants throughout the disease course. Transmission was observed in 10 mother-infant pairs over a one-year period. Two mothers transmitted virus during the period of initial viremia 14–21 days post inoculation (p.i.) and were classified as early transmitters. Peak viral loads in milk and plasma of early transmitters were similar to other animals, however the early transmitters subsequently displayed a rapid progressor phenotype and failed to control virus expression as well as other animals at 56 days p.i. Eight mothers were classified as late transmitters, with infant infection detected at time points in the chronic stage of the maternal SIV disease course (81 to 360 days). Plasma viral loads, CD4+ T cell counts and SIV-specific antibody titers were similar in late transmitters and non-transmitters. Late breast milk transmission, however, was correlated with higher average milk viral loads and more persistent viral expression in milk 12 to 46 weeks p.i. as compared to non-transmitters. Four mothers failed to transmit virus, despite disease progression and continuous lactation. Conclusion These studies validate the SIV-infected rhesus macaque as a model for breast milk transmission of HIV. As observed in studies of HIV-infected women, transmission occurred at time points throughout the period of lactation. Transmission during the chronic stage of SIV

  4. Fibroblast growth factor 21 in breast milk controls neonatal intestine function

    PubMed Central

    Gavaldà-Navarro, Aleix; Hondares, Elayne; Giralt, Marta; Mampel, Teresa; Iglesias, Roser; Villarroya, Francesc

    2015-01-01

    FGF21 is a hormonal factor with important functions in the control of metabolism. FGF21 is found in rodent and human milk. Radiolabeled FGF21 administered to lactating dams accumulates in milk and is transferred to neonatal gut. The small intestine of neonatal (but not adult) mice highly expresses β-Klotho in the luminal area. FGF21-KO pups fed by FGF21-KO dams showed decreased expression and circulating levels of incretins (GIP and GLP-1), reduced gene expression of intestinal lactase and maltase-glucoamylase, and low levels of galactose in plasma, all associated with a mild decrease in body weight. When FGF21-KO pups were nursed by wild-type dams (expressing FGF21 in milk), intestinal peptides and digestive enzymes were up-regulated, lactase enzymatic activity was induced, and galactose levels and body weight were normalized. Neonatal intestine explants were sensitive to FGF21, as evidenced by enhanced ERK1/2 phosphorylation. Oral infusion of FGF21 into neonatal pups induced expression of intestinal hormone factors and digestive enzymes, lactase activity and lactose absorption. These findings reveal a novel role of FGF21 as a hormonal factor contributing to neonatal intestinal function via its presence in maternal milk. Appropriate signaling of FGF21 to neonate is necessary to ensure optimal digestive and endocrine function in developing intestine. PMID:26329882

  5. Fibroblast growth factor 21 in breast milk controls neonatal intestine function.

    PubMed

    Gavaldà-Navarro, Aleix; Hondares, Elayne; Giralt, Marta; Mampel, Teresa; Iglesias, Roser; Villarroya, Francesc

    2015-01-01

    FGF21 is a hormonal factor with important functions in the control of metabolism. FGF21 is found in rodent and human milk. Radiolabeled FGF21 administered to lactating dams accumulates in milk and is transferred to neonatal gut. The small intestine of neonatal (but not adult) mice highly expresses β-Klotho in the luminal area. FGF21-KO pups fed by FGF21-KO dams showed decreased expression and circulating levels of incretins (GIP and GLP-1), reduced gene expression of intestinal lactase and maltase-glucoamylase, and low levels of galactose in plasma, all associated with a mild decrease in body weight. When FGF21-KO pups were nursed by wild-type dams (expressing FGF21 in milk), intestinal peptides and digestive enzymes were up-regulated, lactase enzymatic activity was induced, and galactose levels and body weight were normalized. Neonatal intestine explants were sensitive to FGF21, as evidenced by enhanced ERK1/2 phosphorylation. Oral infusion of FGF21 into neonatal pups induced expression of intestinal hormone factors and digestive enzymes, lactase activity and lactose absorption. These findings reveal a novel role of FGF21 as a hormonal factor contributing to neonatal intestinal function via its presence in maternal milk. Appropriate signaling of FGF21 to neonate is necessary to ensure optimal digestive and endocrine function in developing intestine. PMID:26329882

  6. Levels of innate immune factors in preterm and term mothers' breast milk during the 1st month postpartum.

    PubMed

    Trend, Stephanie; Strunk, Tobias; Lloyd, Megan L; Kok, Chooi Heen; Metcalfe, Jessica; Geddes, Donna T; Lai, Ching Tat; Richmond, Peter; Doherty, Dorota A; Simmer, Karen; Currie, Andrew

    2016-04-14

    There is a paucity of data on the effect of preterm birth on the immunological composition of breast milk throughout the different stages of lactation. We aimed to characterise the effects of preterm birth on the levels of immune factors in milk during the 1st month postpartum, to determine whether preterm milk is deficient in antimicrobial factors. Colostrum (days 2-5 postpartum), transitional milk (days 8-12) and mature milk (days 26-30) were collected from mothers of extremely preterm (<28 weeks of gestation, n 15), very preterm (28-<32 weeks of gestation, n 15), moderately preterm (32-<37 weeks of gestation, n 15) and term infants (37-41 weeks of gestation, n 15). Total protein, lactoferrin, secretory IgA, soluble CD14 receptor (sCD14), transforming growth factor-β2 (TGF-β2), α defensin 5 (HD5), β defensins 1 (HBD1) and 2, IL-6, IL-10, IL-13, interferon-γ, TNF-α and lysozyme (LZ) were quantified in milk. We examined the effects of lactation stage, gestational age, volume of milk expressed, mode of delivery, parity and maternal infection on milk immune factor concentrations using repeated-measures regression analysis. The concentrations of all factors except LZ and HD5 decreased over the 1st month postpartum. Extremely preterm mothers had significantly higher concentrations of HBD1 and TGF-β2 in colostrum than term mothers did. After controlling for other variables in regression analyses, preterm birth was associated with higher concentrations of HBD1, LZ and sCD14 in milk samples. In conclusion, preterm breast milk contains significantly higher concentrations of some immune proteins than term breast milk. PMID:26891901

  7. Environmental factors influencing blackfly populations

    PubMed Central

    Carlsson, G.

    1967-01-01

    Much more information is required on the distribution of blackflies in various parts of the world, and in many cases an adequate methodology for obtaining such information still has to be worked out. A detailed methodology for the collection of information about blackflies is given, which was developed for investigations mainly in the Holarctic regions but is basically applicable to other parts of the world. A brief survey of the population dynamics of various species of blackflies in various parts of the Holarctic regions is given, and the main factors influencing the population dynamics are discussed. Interspecific and intraspecific fluctuations in natural blackfly populations are attributed chiefly to abiotic environmental factors rather than to competition. Larval competition in a given microhabitat is mainly individual, though specimens belonging to a given species may have a slightly more favourable position than others. The use of parasites and in particular the replacement of one species by another are promising methods of blackfly control. Predators are not generally likely to prove useful for this purpose. PMID:5300046

  8. Gamma irradiation influence on physical properties of milk proteins

    NASA Astrophysics Data System (ADS)

    Cieśla, K.; Salmieri, S.; Lacroix, M.; Tien, C. Le

    2004-09-01

    Gamma irradiation was found to be an effective method for the improvement of both barrier and mechanical properties of the edible films and coatings based on calcium and sodium caseinates alone or combined with some globular proteins. Our current studies concern gamma irradiation influence on the physical properties of calcium caseinate-whey protein isolate-glycerol (1:1:1) solutions and gels, used for films preparation. Irradiation of solutions was carried out with Co-60 gamma rays applying 0 and 32 kGy dose. The increase in viscosity of solutions was found after irradiation connected to induced crosslinking. Lower viscosity values were detected, however, after heating of the solutions irradiated with a 32 kGy dose than after heating of the non-irradiated ones regarding differences in the structure of gels and resulting in different temperature-viscosity curves that were recorded for the irradiated and the non-irradiated samples during heating and cooling. Creation of less stiff but better ordered gels after irradiation arises probably from reorganisation of aperiodic helical phase and β-sheets, in particular from increase of β-strands, detected by FTIR. Films obtained from these gels are characterised by improved barrier properties and mechanical resistance and are more rigid than those prepared from the non-irradiated gels. The route of gel creation was investigated for the control and the irradiated samples during heating and the subsequent cooling.

  9. Factors influencing boar sperm cryosurvival.

    PubMed

    Roca, J; Hernández, M; Carvajal, G; Vázquez, J M; Martínez, E A

    2006-10-01

    Optimal sperm cryopreservation is a prerequisite for the sustainable commercial application of frozen-thawed boar semen for AI. Three experiments were performed to identify factors influencing variability of postthaw sperm survival among 464 boar ejaculates. Sperm-rich ejaculate fractions were cryopre-served using a standard freezing-thawing procedure for 0.5-mL plastic straws and computer-controlled freezing equipment. Postthaw sperm motility (assessed with a computer-assisted semen analysis system) and viability (simultaneously probed by flow cytometry analysis after triple-fluorescent stain), evaluated 30 and 150 min postthaw, were used to estimate the success of cryopreservation. In the first experiment, 168 unselected ejaculates (1 ejaculate/boar), from boars of 6 breeds with a wide age range (8 to 48 mo), were cryopreserved over a 12-mo period to evaluate the predictive value of boar (breed and age), semen collection, transport variables (season of ejaculate collection, interval between collections, and ejaculate temperature exposure), initial semen traits, and sperm quality before freezing on sperm survival after freezing-thawing. In Exp. 2, 4 ejaculates from each of 29 boars, preselected according to their initial semen traits and sperm quality before freezing, were collected and frozen over a 6-mo period to evaluate the influence of interboar and intraboar ejaculate variability in the survival of sperm after cryopreservation. In Exp. 3, 12 ejaculates preselected as for Exp. 2, from each of 15 boars with known good sperm cryosurvival, were collected and frozen over a 12-mo period to estimate the sustainability of sperm cryosurvival between ejaculates over time. Boar and semen collection and transport variables were not predictive of sperm cryosurvival among ejaculates. Initial semen traits and sperm quality variables observed before freezing explained 23.2 and 10.9%, respectively, of the variation in postthaw sperm motility and viability. However, more that

  10. [Endocrine factors influencing melanoma progression].

    PubMed

    Dobos, Judit

    2009-03-01

    According to recent findings that beside cancers traditionally considered as hormone-dependent, several other tumor types show different behavior in the two sexes, indicating the possible role of endocrine factors in the course of these diseases. The possibility that endocrine factors may influence the clinical course of human malignant melanoma is suggested by the higher survival rate in premenopausal vs. postmenopausal women or men of any ages. However, investigations on the sex hormone receptor status of human cutaneous melanomas and experiments attempting to support the epidemiological results yielded conflicting results. In our human melanoma cell lines we failed to detect steroid receptors at protein level, while quantitative PCR demonstrated that their mRNA expression level was orders of magnitude lower compared to the positive control cell lines. Sex hormones did not influence the in vitro features of the human melanoma cells considerably. On the other hand, glucocorticoid receptor was present both at mRNA and protein level, although dexamethasone was effective in vitro only at high doses. Our previous experiments showed that intrasplenic injection of human melanoma cells resulted in a significantly higher number of liver colonies in male than in female SCID mice. We now show that this difference evolves during the first day. After injection into the tail vein we did not observe gender-dependent difference in the efficiency of pulmonary colonization. Examining the pattern of metastasis formation after intracardiac injection, we have found differences between the two sexes in the incidence or number of colonies only in the case of the liver but not in other organs. We concluded that the observed phenomenon is specific to the liver; therefore we investigated the effects of 2-methoxyestradiol, an endogenous metabolite of estradiol produced mainly in the liver, with an estrogen receptor-independent antitumor activity. 2ME2 effectively inhibited melanoma cell

  11. Casein polymorphism heterogeneity influences casein micelle size in milk of individual cows.

    PubMed

    Day, L; Williams, R P W; Otter, D; Augustin, M A

    2015-06-01

    Milk samples from individual cows producing small (148-155 nm) or large (177-222 nm) casein micelles were selected to investigate the relationship between the individual casein proteins, specifically κ- and β-casein phenotypes, and casein micelle size. Only κ-casein AA and β-casein A1A1, A1A2 and A2A2 phenotypes were found in the large casein micelle group. Among the small micelle group, both κ-casein and β-casein phenotypes were more diverse. κ-Casein AB was the dominant phenotype, and 3 combinations (AA, AB, and BB) were present in the small casein micelle group. A considerable mix of β-casein phenotypes was found, including B and I variants, which were only found in the small casein micelle group. The relative amount of κ-casein to total casein was significantly higher in the small micelle group, and the nonglycosylated and glycosylated κ-casein contents were higher in the milks with small casein micelles (primarily with κ-casein AB and BB variants) compared with the large micelle group. The ratio of glycosylated to nonglycosylated κ-casein was higher in the milks with small casein micelles compared with the milks with large casein micelles. This suggests that although the amount of κ-casein (both glycosylated and nonglycosylated) is associated with micelle size, an increased proportion of glycosylated κ-casein could be a more important and favorable factor for small micelle size. This suggests that the increased spatial requirement due to addition of the glycosyl group with increasing extent of glycosylation of κ-casein is one mechanism that controls casein micelle assembly and growth. In addition, increased electrostatic repulsion due to the sialyl residues on the glycosyl group could be a contributory factor. PMID:25828659

  12. Influence of cow or goat milk consumption on antioxidant defence and lipid peroxidation during chronic iron repletion.

    PubMed

    Díaz-Castro, Javier; Pérez-Sánchez, Luis J; Ramírez López-Frías, Mercedes; López-Aliaga, Inmaculada; Nestares, Teresa; Alférez, María J M; Ojeda, M Luisa; Campos, Margarita S

    2012-07-14

    Despite Fe deficiency and overload having been widely studied, no studies are available about the influence of milk consumption on antioxidant defence and lipid peroxidation during the course of these highly prevalent cases. The objective of the present study was to assess the influence of cow or goat milk-based diets, either with normal or Fe-overload, on antioxidant defence and lipid peroxidation in the liver, brain and erythrocytes of control and anaemic rats after chronic Fe repletion. Weanling male rats were randomly divided into two groups: a control group receiving a normal-Fe diet (45 mg/kg) and an anaemic group receiving a low-Fe diet (5 mg/kg) for 40 d. Control and anaemic rats were fed goat or cow milk-based diets, either with normal Fe or Fe-overload (450 mg/kg), for 30 or 50 d. Fe-deficiency anaemia did not have any effect on antioxidant enzymes or lipid peroxidation in the organs studied. During chronic Fe repletion, superoxide dismutase (SOD) activity was higher in the group of animals fed the cow milk diet compared with the group consuming goat milk. The slight modification of catalase and glutathione peroxidise activities in animals fed the cow milk-based diet reveals that these enzymes are unable to neutralise and scavenge the high generation of free radicals produced. The animals fed the cow milk diet showed higher rates of lipid peroxidation compared with those receiving the goat milk diet, which directly correlated with the increase in SOD activity. It was concluded that goat milk has positive effects on antioxidant defence, even in a situation of Fe overload, limiting lipid peroxidation. PMID:22018161

  13. Influence of kid rearing systems on milk composition and yield of Murciano-Granadina dairy goats.

    PubMed

    Peris, S; Caja, G; Such, X; Casals, R; Ferret, A; Torre, C

    1997-12-01

    One-hundred eight lactations of Murciano-Granadina goats from different years were used to compare two kid rearing systems. Goats were separated into two groups: suckling and milking. Dams in the suckling group were milked once daily until kids were weaned (wk 0 to 7) and then were milked twice daily. Dams in the milking group were separated from their kids at 48 h after birth; then, kids were raised artificially, and goats were milked twice daily. Total milk yield was estimated according to the oxytocin method during suckling. Stage of lactation, parity, prolificacy, and year effects on milk yield and composition were also studied. As expected, during the first 7 wk of lactation, marketable milk was higher for dams that were milked than for dams that were suckled. Neither milk yield nor milk composition throughout the entire lactation was affected by group or prolificacy with the exception of the percentage of milk CP. The lactation curve peaked at wk 4 or 5 and declined slowly afterward. First parity goats had the lowest milk yield but the highest fat and protein percentages. Third parity goats had the highest milk yield. The separation of kids from their dams after birth did not affect total lactation performance because of the minimal importance of the neuroendocrine milk ejection reflex in goats compared with that of other ruminants. PMID:9436106

  14. Influence of grazing practices on cow milk quality: a case study on the Comarnic-Poieni bauxite quarry, Romania.

    PubMed

    Lorinţ, Csaba; Rădulescu, Monica; Buia, Grigore

    2012-04-01

    The current study represents a preliminary investigation made into the influence of cattle grazing in the area of a bauxite quarry (Comarnic-Poieni, Romania) on the cow milk chemistry. Weathering and surface runoff in the bauxite quarry contaminate the local chemistry of the soil, vegetation and water. During cattle transhumance, cyclic feeding patterns occur, with grazing alternating between clean pastures and the area of the quarry. Soil and water samples were collected from the contaminated area of the quarry. Raw milk samples were collected during two stages, corresponding to the periods of grazing on clean pasture and the quarry area, respectively. Based on the obtained data, the relationship between cattle grazing and the composition of milk was interpreted. Preliminary results indicated a direct correlation of increased concentration of Al in the milk, following grazing in the bauxite quarry. PMID:21986677

  15. Factors that Influence Participation in Online Learning

    ERIC Educational Resources Information Center

    Vonderwell, Selma; Zachariah, Sajit

    2005-01-01

    This study explored what factors influenced learner participation in two sections of a graduate online course at a Midwestern university. Findings indicated that online learner participation and patterns of participation are influenced by the following factors: technology and interface characteristics, content area experience, student roles and…

  16. Does milk and dairy consumption during pregnancy influence fetal growth and infant birthweight? A systematic literature review

    PubMed Central

    Brantsæter, Anne Lise; Olafsdottir, Anna S.; Forsum, Elisabet; Olsen, Sjurdur F.; Thorsdottir, Inga

    2012-01-01

    It is increasingly acknowledged that the maternal diet influences fetal development and health of the child. Milk and milk products contribute essential nutrients and bioactive substances; they are of ample supply and have a long tradition in Nordic countries. To revise and update dietary guidelines for pregnant women valid in Nordic countries, the Pregnancy and Lactation expert group within the NNR5 project identified a need to systematically review recent scientific data on infant growth measures and maternal milk consumption. The objective of this study was to assess the influence of milk and dairy consumption during pregnancy on fetal growth through a systematic review of studies published between January 2000 and December 2011. A literature search was run in June 2011. Two authors independently selected studies for inclusion from the 495 abstracts according to predefined eligibility criteria. A complementary search in January 2012 revealed 64 additional abstracts published during the period June to December 2011, among them one study of interest previously identified. Of the 33 studies extracted, eight were relevant research papers. Five were prospective cohort studies (including a retrospective chart review), one was a case–control study, and two were retrospective cohort studies. For fetal length or infant birth length, three studies reported no association and two reported positive associations with milk or dairy consumption. For birthweight related outcomes, two studies reported no associations, and four studies reported positive associations with milk and/or dairy consumption. There was large heterogeneity in exposure range and effect size between studies. A beneficial fetal growth-increase was most pronounced for increasing maternal milk intake in the lower end of the consumption range. Evidence from prospective cohort studies is limited but suggestive that moderate milk consumption relative to none or very low intake, is positively associated with

  17. Risk factors associated with selected indicators of milk quality in semiarid northeastern Brazil.

    PubMed

    Oliveira, C J B; Lopes Júnior, W D; Queiroga, R C R E; Givisiez, P E N; Azevedo, P S; Pereira, W E; Gebreyes, W A

    2011-06-01

    The aim of this study was to gain information on quality traits, mainly bacterial and somatic cell counts of bulk milk, produced by small- and medium-scale producers in a semiarid northeastern region of Brazil and to identify and characterize possible risk factors associated with those quality traits. A cross-sectional study was performed on 50 farms. Bulk milk samples were collected for bacterial and somatic cell counts. Additionally, information about farm demographics, general management practices, hygiene, and milking procedures was also obtained. Multivariable analysis using logistic regression was performed with predictors previously identified by univariate analysis using a Fisher's Exact test. Aerobic mesophilic bacteria counts varied from 3.59 log to 6.95 log cfu/mL, with geometric mean of 5.27 log cfu/mL. Mean total coliform count was 3.27 log (1.52 log to 5.89 log) most probable number (MPN)/mL, whereas mean thermotolerant coliforms was 2.38 log (1.48 log to 4.75 log) MPN/mL. A high positive correlation was observed between aerobic mesophilic bacteria and coliform counts. Although most farms met the standard for the current regulations for total bacteria (88%) and somatic cell counts (94%), nearly half of the producers (46%) would have problems in achieving the 2012 threshold limit for total bacteria count if no improvement in milk quality occurs. Mean value for staphylococci was 3.99 log (2.31 log to 6.24 log) cfu/mL, and Staphylococcus aureus was detected in 33 (66%) farms. Premilking teat-end wash procedure (odds ratio=0.191) and postmilking teat dip (odds ratio=0.67) were associated with lower aerobic mesophilic bacteria and Staphylococcus aureus counts in bulk milk, respectively. Considering that the farm characteristics in this study are representative of the semiarid northeastern region, these findings encourage further investigations for supporting intervention measures intended to improve the quality of milk produced by smallholders. PMID

  18. Investigating associations between milk metabolite profiles and milk traits of Holstein cows.

    PubMed

    Melzer, N; Wittenburg, D; Hartwig, S; Jakubowski, S; Kesting, U; Willmitzer, L; Lisec, J; Reinsch, N; Repsilber, D

    2013-03-01

    In the field of dairy cattle research, it is of great interest to improve the detection and prevention of diseases (e.g., mastitis and ketosis) and monitor specific traits related to the state of health and management. During the standard milk performance test, traditional milk traits are monitored, and quality and quantity are screened. In addition to the standard test, it is also now possible to analyze milk metabolites in a high-throughput manner and to consider them in connection with milk traits to identify functionally important metabolites that can also serve as biomarker candidates. We present a study in which 190 milk metabolites and 14 milk traits of 1,305 Holstein cows on 18 commercial farms were investigated to characterize interrelations of milk metabolites between each other, to milk traits from the milk standard performance test, and to influencing factors such as farm and sire effect (half-sib structure). The effect of influencing factors (e.g., farm) varied among metabolites and traditional milk traits. The investigations of associations between metabolites and milk traits revealed groups of metabolites that show, for example, positive correlations to protein and casein, and negative correlations to lactose and pH. On the other hand, groups of metabolites jointly associated with the investigated milk traits can be identified and functionally discussed. To enable a multivariate investigation, 2 machine learning methods were applied to detect important metabolites that are highly correlated with the investigated traditional milk traits. For somatic cell score, uracil, lactic acid, and 9 other important metabolites were detected. Lactic acid has already been proposed as a biomarker candidate for mastitis in the recent literature. In conclusion, we found sets of metabolites eligible to predict milk traits, enabling the analysis of milk traits from a metabolic perspective and discussion of the possible functional background for some of the detected

  19. Factors influencing dust suppressant effectiveness

    SciTech Connect

    Copeland, C.R.; Eisele, T.C.; Chesney, D.J.; Kawatra, S.K.

    2008-11-15

    Water sprays are a common method used to reduce particulate matter (PM) emissions. Various factors such as wettability, surface area coverage, fine particle engulfment rates, interparticle adhesion forces, suppressant penetration and suppressant longevity have all been suggested as critical factors in achieving effective PM control. However, it has not been established which of these factors are the most important. Experimental work indicated that suppressant penetration is the most critical of these factors. The length of time after application that suppressants were effective was also improved by using hygroscopic reagents that retained moisture to prevent evaporation. Maximizing suppressant penetration and improving suppressant longevity led to an average 86% reduction in PM10 concentrations in laboratory dust tower tests.

  20. Genetic factors influencing alcohol dependence

    PubMed Central

    Mayfield, R D; Harris, R A; Schuckit, M A

    2008-01-01

    Plentiful data from both animal and human studies support the importance of genetic influences in substance abuse and dependence (Bierut et al., 1998; Tsuang et al., 1998; Kendler et al., 2003). This review summarizes the evidence supporting such genetic influences, places them into perspective regarding animal and human studies, discusses the importance of both genes and environment, and highlights some specific genes of interest regarding the vulnerabilities for problems associated with alcohol use disorders. A long history of repetitive heavy use of alcohol exists across generations as well as the high prevalence of alcohol-related problems in Western societies. Moreover, the information offered here addresses the importance of more general issues regarding genetics and gene expression related to alcohol abuse and dependence. PMID:18362899

  1. Lactobacillus GG-fermented milk prevents DSS-induced colitis and regulates intestinal epithelial homeostasis through activation of epidermal growth factor receptor

    PubMed Central

    Yoda, Kazutoyo; Miyazawa, Kenji; Hosoda, Masataka; Hiramatsu, Masaru; Yan, Fang; He, Fang

    2014-01-01

    Background Fermented milk is considered one of the best sources for efficient consumption of probiotic strains by hosts to promote good health. The purpose of this study was to investigate the effects of orally administering LGG-fermented milk (LGG milk) on intestinal inflammation and injury and to study the mechanisms of LGG milk's action. Methods LGG milk and non-LGG-fermented milk (non-LGG milk) were administered through gavage to mice before and during dextran sodium sulfate (DSS)-induced intestinal injury and colitis. Inflammatory/injury score and colon length were assessed. Intestinal epithelial cells were treated with the soluble fraction of LGG milk to detect its effects on the epidermal growth factor receptor (EGFR) and its down stream target, Akt activation, cytokine-induced apoptosis, and hydrogen peroxide (H2O2)-induced disruption of tight junctions. Results LGG milk treatment significantly reduced DSS-induced colonic inflammation and injury, and colon shortening in mice, compared to that in non-LGG milk-treated and untreated mice. The soluble fraction of LGG milk, but not non-LGG milk, stimulated activation of EGFR and Akt in a concentration-dependent manner, suppressed cytokine-induced apoptosis, and attenuated H2O2-induced disruption of tight junction complex in the intestinal epithelial cells. These effects of LGG milk were blocked by the EGFR kinase inhibitor. LGG milk, but not non-LGG milk, contained two soluble proteins, p40 and p75, which have been reported to promote survival and growth of intestinal epithelial cells through activation of EGFR. Depletion of p40 and p75 from LGG milk abolished the effects of LGG milk on prevention of cytokine-induced apoptosis and H2O2-induced disruption of tight junctions. Conclusions These results suggest that LGG milk may regulate intestinal epithelial homeostasis and potentially prevent intestinal inflammatory diseases through activation of EGFR by LGG-derived proteins. PMID:23468308

  2. The Environmental Factors Influencing Attrition.

    ERIC Educational Resources Information Center

    Villella, Edward F.

    1986-01-01

    Offers an economics/business-management perspective on student attrition, focusing on the external macro-environment (including such factors as government funding of education, changing enrollment patterns, and the increased number of postsecondary institutions) and the internal micro-environment (exhibiting characteristics of intangibility,…

  3. Expression, purification, and characterization of recombinant human and murine milk fat globule-epidermal growth factor-factor 8.

    PubMed

    Castellanos, Erick R; Ciferri, Claudio; Phung, Wilson; Sandoval, Wendy; Matsumoto, Marissa L

    2016-08-01

    Milk fat globule-epidermal growth factor-factor 8 (MFG-E8), as its name suggests, is a major glycoprotein component of milk fat globules secreted by the mammary epithelium. Although its role in milk fat production is unclear, MFG-E8 has been shown to act as a bridge linking apoptotic cells to phagocytes for removal of these dying cells. MFG-E8 is capable of bridging these two very different cell types via interactions through both its epidermal growth factor (EGF)-like domain(s) and its lectin-type C domains. The EGF-like domain interacts with αVβ3 and αVβ5 integrins on the surface of phagocytes, whereas the C domains bind phosphatidylserine found on the surface of apoptotic cells. In an attempt to purify full-length, recombinant MFG-E8 expressed in either insect cells or CHO cells, we find that it is highly aggregated. Systematic truncation of the domain architecture of MFG-E8 indicates that the C domains are mainly responsible for the aggregation propensity. Addition of Triton X-100 to the conditioned cell culture media allowed partial recovery of non-aggregated, full-length MFG-E8. A more comprehensive detergent screen identified CHAPS as a stabilizer of MFG-E8 and allowed purification of a significant portion of non-aggregated, full-length protein. The CHAPS-stabilized recombinant MFG-E8 retained its natural ability to bind both αVβ3 and αVβ5 integrins and phosphatidylserine suggesting that it is properly folded and active. Herein we describe an efficient purification method for production of non-aggregated, full-length MFG-E8. PMID:27102803

  4. Supplementary feeding at milking and minimum milking interval effects on cow traffic and milking performance in a pasture-based automatic milking system.

    PubMed

    Jago, Jenny G; Davis, Kendra L; Copeman, Peter J; Ohnstad, Ian; Woolford, Murray M

    2007-11-01

    In extensive pastoral dairy farming systems herds graze 12 months of the year with the majority fed a near-100% pasture or conserved pasture diet. The viability of automatic milking in these systems will depend partly upon the amount of supplementary feed necessary to encourage cows to walk from the pasture to the milking unit but also on the efficient use of the automatic milking system (AMS). This paper describes a study to determine the importance of offering concentrate in the milking unit and the effect of minimum milking interval on cow movement and milking performance in a pasture-based AMS. The effects of feeding rate (FR0=0 kg or FR1=1 kg crushed barley/d) and minimum milking interval (MM6=6 h or MM12=12 h) on cow movement and behaviour during milking were studied in a multi-factorial cross-over (feeding level only, 4 weeks per treatment) experiment involving 27 mixed-breed cows milked through a single AMS. Feeding 1 kg barley in the milking unit resulted in a higher visiting frequency to the pre-selection unit (FR0=4.6 visits/d, FR1=5.4 visits/d, sed=0.35, P<0.05) and a higher yield (FR0=22.5 kg/d, FR1=23.6 kg/d, sed=0.385, P<0.01) but had no effect on milking frequency (FR0=1.6 milkings/d, FR1=1.7 milkings/d, sed=0.04, NS). Minimum milking interval was the major factor influencing milking frequency (MM6=1.9, MM12=1.4 milkings/d, sed=0.15, P<0.01). The absence of feeding in the milking unit had no negative effect on behaviour during milking or the number of cows that had to be manually driven from the paddock. The results show that automatic milking can be combined with a near-100% pasture diet and that milking interval is an important determinant for maximizing milk harvested per AMS. PMID:17922936

  5. Factors influencing perceived angular velocity

    NASA Technical Reports Server (NTRS)

    Kaiser, Mary K.; Calderone, Jack B.

    1991-01-01

    Angular velocity perception is examined for rotations both in depth and in the image plane and the influence of several object properties on this motion parameter is explored. Two major object properties are considered, namely, texture density which determines the rate of edge transitions for rotations in depth, i.e., the number of texture elements that pass an object's boundary per unit of time, and object size which determines the tangential linear velocities and 2D image velocities of texture elements for a given angular velocity. Results of experiments show that edge-transition rate biased angular velocity estimates only when edges were highly salient. Element velocities had an impact on perceived angular velocity; this bias was associated with 2D image velocity rather than 3D tangential velocity. Despite these biases judgements were most strongly determined by the true angular velocity. Sensitivity to this higher order motion parameter appeared to be good for rotations both in depth (y-axis) and parallel to the line of sight (z-axis).

  6. Milk consumption during pregnancy increases birth weight, a risk factor for the development of diseases of civilization.

    PubMed

    Melnik, Bodo C; John, Swen Malte; Schmitz, Gerd

    2015-01-01

    Antenatal dietary lifestyle intervention and nutrition during pregnancy and early postnatal life are important for appropriate lifelong metabolic programming. Epidemiological evidence underlines the crucial role of increased birth weight as a risk factor for the development of chronic diseases of civilization such as obesity, diabetes and cancer. Obstetricians and general practitioners usually recommend milk consumption during pregnancy as a nutrient enriched in valuable proteins and calcium for bone growth. However, milk is not just a simple nutrient, but has been recognized to function as an endocrine signaling system promoting anabolism and postnatal growth by activating the nutrient-sensitive kinase mTORC1. Moreover, pasteurized cow's milk transfers biologically active exosomal microRNAs into the systemic circulation of the milk consumer apparently affecting more than 11,000 human genes including the mTORC1-signaling pathway. This review provides literature evidence and evidence derived from translational research that milk consumption during pregnancy increases gestational, placental, fetal and birth weight. Increased birth weight is a risk factor for the development of diseases of civilization thus involving key disciplines of medicine. With regard to the presented evidence we suggest that dietary recommendations promoting milk consumption during pregnancy have to be re-evaluated. PMID:25592553

  7. Review of present knowledge on machine milking and intensive milk production in dromedary camels and future challenges.

    PubMed

    Nagy, Peter; Juhasz, Judit

    2016-06-01

    The camel dairy industry has gone through major development in the last decade. The world's first large-scale camel dairy farm was established 10 years ago in Dubai, United Arab Emirates, and since then, several commercial and scientific projects have been started, and more studies have been published demonstrating increasing interest in camel milk. The aims of this paper are to summarize relevant published data on factors influencing milk production under intensive management, compare those with our own observations obtained from Emirates Industry for Camel Milk and Products (EICMP), and highlight areas of research that are indispensable for further development. As in other species, the most important factors influencing milk yield are genetic and individual variation, age, parity, stage of lactation, nutrition, management, season, photoperiod, etc. However, the precise role of the various factors has not been thoroughly studied in camels and based on our understanding of the basic physiological processes, endocrine control is minimal. In addition, machine milking of dromedaries is still at early stage and requires research for improvement of the technology and defining factors affecting and improving milk ejection. The role of environment (like photoperiod, nutrition) should also be investigated as there is significant annual variation both in milk quantity and quality that might influence the processing characteristics of raw camel milk. The large pool of animals and thoroughly recorded data at EICMP provide an excellent opportunity for increasing milk production and improving milk quality using various methods, like feeding, management, reproduction, selection, and breeding. PMID:26992732

  8. Polymorphisms in the promoter region of the bovine lactoferrin gene influence milk somatic cell score and milk production traits in Chinese Holstein cows.

    PubMed

    Mao, Yongjiang; Zhu, Xiaorui; Xing, Shiyu; Zhang, Meirong; Zhang, Huimin; Wang, Xiaolong; Karrow, Niel; Yang, Liguo; Yang, Zhangping

    2015-12-01

    Lactoferrin is an iron-binding protein found in cow's milk that plays an important role in preventing mastitis caused by intramammary infection. In this study, 20 Chinese Holstein cows were selected randomly for PCR amplification and sequencing of the bovine lactoferrin gene promoter region and used for SNP discovery in the region between nucleotide positions -461 to -132. Three SNPs (-270T>C, -190G>A and -156A>G) were identified in bovine lactoferrin, then Chinese Holstein cows (n=866) were genotyped using Sequenom MassARRAY (Sequenom Inc., San Diego, CA) based on the previous SNP information in this study, and the associations between SNPs or haplotype and milk somatic cell score (SCS) and production traits were analyzed by the least squares method in the GLM procedure of SAS. SNPs -270T>C and -156A>G showed close linkage disequilibrium (r(2)=0.76). The SNP -190G>A showed a significant association with SCS, and individuals with genotype GG had higher SCS than genotypes AG and AA. Associations were found between the SNPs -270T>C and -190G>A with SCS and the milk composition. The software MatInspector revealed that these SNPs were located within several potential transcription factor binding sites, including NF-κB p50, KLF7 and SP1, and may alter gene expression, but further investigation will be required to elucidate the biological and practical relevance of these SNPs. PMID:26679804

  9. Farm and socio-economic characteristics of smallholder milk producers and their influence on technology adoption in Central Mexico.

    PubMed

    García, Carlos Galdino Martínez; Dorward, Peter; Rehman, Tahir

    2012-08-01

    In order to identify the factors influencing adoption of technologies promoted by government to small-scale dairy farmers in the highlands of central Mexico, a field survey was conducted. A total of 115 farmers were grouped through cluster analysis (CA) and divided into three wealth status categories (high, medium and low) using wealth ranking. Chi-square analysis was used to examine the association of wealth status with technology adoption. Four groups of farms were differentiated in terms of farms' dimensions, farmers' education, sources of incomes, wealth status, management of herd, monetary support by government and technological availability. Statistical differences (p < 0.05) were observed in the milk yield per herd per year among groups. Government organizations (GO) participated little in the promotion of the 17 technologies identified, six of which focused on crop or forage production and 11 of which were related to animal husbandry. Relatives and other farmers played an important role in knowledge diffusion and technology adoption. Although wealth status had a significant association (p < 0.05) with adoption, other factors including importance of the technology to farmers, usefulness and productive benefits of innovations together with farmers' knowledge of them, were important. It is concluded that the analysis of the information per group and wealth status was useful to identify suitable crop or forage related and animal husbandry technologies per group and wealth status of farmers. Therefore the characterizations of farmers could provide a useful starting point for the design and delivery of more appropriate and effective extension. PMID:22297420

  10. What Factors Influence Wind Perceptions

    NASA Astrophysics Data System (ADS)

    Stein, Tatiana

    Over the last decade, wind power has emerged as a possible source of energy and has attracted the attention of homeowners and policy makers worldwide. Many technological hurdles have been overcome in the last few years that make this technology feasible and economical. The United States has added more wind power than any other type of electric generation in 2012. Depending on the location, wind resources have shown to have the potential to offer 20% of the nation's electricity; a single, large wind turbine has the capacity to produce enough electricity to power 350 homes. Throughout the development of wind turbines, however, energy companies have seen significant public opposition towards the tall white structures. The purpose of this research was to measure peoples' perceptions on wind turbine development throughout their growth, from proposal to existing phase. Three hypotheses were developed based on the participant's political affiliation, proximity and knowledge of wind turbines. To validate these hypotheses, participants were asked an array of questions regarding their perception on economic, environmental, and social impacts of wind turbines with an online service called Amazon Mechanical Turk. The responses were from residents living in the United States and required them to provide their zip code for subsequent analysis. The analysis from the data obtained suggests that participants are favorable towards wind turbine development and would be supportive of using the technology in their community. Political affiliation and proximity to the nearest wind turbine in any phase of development (proposal, construction, existing) were also analyzed to determine if they had an effect on a person's overall perception on wind turbines and their technology. From the analysis, political affiliation was seen to be an indirect factor to understanding favorability towards wind turbines; the more liberal you are, the more supportive you will be towards renewable energy use

  11. Disposition of toxic metals in the agricultural food chain. 1. Steady-state bovine milk biotransfer factors

    SciTech Connect

    Stevens, J.B. )

    1991-07-01

    Pharmacokinetic analyses were conducted on published experimental data to estimate steady-state bovine milk biotransfer factors for six metals-arsenic, cadmium, chromium, lead, mercury, and nickel. Both long-term feeding studies and bolus oral dose date were evaluated. This analysis indicated that, of the metals studied, lead and arsenic transfer to milk to the greatest extent, followed by chromium, mercury, and cadmium. The lead biotransfer factor is approximately 50 times that calculated for cadmium. Insufficient information was available to calculate an accurate biotransfer factor for nickel. Metals, as components of sludge (particularly lead, arsenic, and cadmium), were not found to produce significant elevations in analyte concentrations in milk. These findings suggest that metals contained in sludge may not be as bioavailable to dairy cows as metal salts.

  12. Assessment of Risk Factors in Milk Contamination with Staphylococcus aureus in Urban and Peri-Urban Small-Holder Dairy Farming in Central Ethiopia.

    PubMed

    Tigabu, E; Asrat, D; Kassa, T; Sinmegn, T; Molla, B; Gebreyes, W

    2015-12-01

    Assessment of risk factors associated with milk production systems is central to ensuring quality and safety of milk and milk products. This study was aimed at identifying possible risk factors in milk contamination in urban and peri-urban areas of the central high lands of Ethiopia. A total of 477 on-farm pooled milk (n = 433) and combined bulk milk samples (n = 44) were collected and processed using standard microbiological techniques to isolate and characterize Staphylococcus aureus. In addition, 433 individual farm owners and 22 collection centre owners were interviewed using a structured and pre-tested questionnaire. Multivariate logistic regression was used to determine risk factors. Of the total individual on-farm pooled milk samples analysed (n = 433), it was found that 103 of the individual milk samples (24%) and 17 of the combined bulk milk (39%) were positive for S. aureus. This difference in prevalence was statistically significant. Even though there were a number of potential variables associated with the recovery of S. aureus in bovine milk, four variables including cleaning milk container with hot water and detergent [Adjusted OR: 0.342, 95% CI, (0.166, 0.701)], mastitis check [Adjusted OR: 3.019, 95% CI (1.542, 5.913)], travel time to collection centres [Adjusted OR: 4.932, 95% CI, (2.265, 10.739)] and amount of milk delivered by farmers to collection centres per day [Adjusted OR: 1.059 (1.032, 1.087 β = 0.057)] were found to be statistically significantly associated with isolation of S. aureus. We recommend a targeted educational intervention on defined risk factors to reduce the post-harvest S. aureus contamination of raw milk in urban and peri-urban milk shed areas of central Ethiopia. PMID:25916167

  13. Diet-induced pseudohypoparathyroidism: A hypocalcemia and milk fever risk factor.

    PubMed

    Goff, J P; Liesegang, A; Horst, R L

    2014-03-01

    Subclinical hypocalcemia may affect half of all multiparous cows, and clinical hypocalcemia or milk fever affects approximately 5% of dairy cows each year. This disorder of calcium homeostasis can be induced by several dietary factors. Recent studies implicate high dietary potassium and high dietary cation-anion difference (DCAD) with increased risk of milk fever. The hypothesis tested in this study was that high-DCAD diets fed to prepartum cows reduce tissue sensitivity to parathyroid hormone (PTH), inducing a pseudohypoparathyroid state that diminishes calcium homeostatic responses. Multiparous Jersey cows were fed low- or high-DCAD diets in late gestation, creating a compensated metabolic alkalosis in the high-DCAD cows and a compensated metabolic acidosis in the low-DCAD cows. They then received synthetic PTH injections at 3-h intervals for 48 h. Parathyroid hormone is expected to cause an increase in plasma calcium by increasing renal production of 1,25-dihydroxyvitamin D and increasing bone calcium resorption. Plasma calcium concentration increased at a significantly lower rate in cows fed the high-DCAD diet. Cows fed the high-DCAD diet also produced significantly less 1,25-dihydroxyvitamin D in response to the PTH injections than cows fed the low-DCAD diet. Serum concentrations of the bone resorption marker carboxyterminal telopeptide of type I collagen were numerically lower in cows fed the high-DCAD diet but this difference was not statistically significant. These data provide direct evidence that high-DCAD diets reduce tissue sensitivity to PTH. The metabolic alkalosis associated with high-DCAD diets likely induces a state of pseudohypoparathyroidism in some dairy cows at the onset of lactation, resulting in hypocalcemia and milk fever. PMID:24418271

  14. Producing specific milks for speciality cheeses.

    PubMed

    Bertoni, G; Calamari, L; Maianti, M G

    2001-05-01

    Protected denomination of origin (PDO) cheeses have distinctive sensorial characteristics. They can be made only from raw milk possessing specific features, which is processed through the 'art' of the cheesemaker. In general, the distinctive sensorial traits of PDO cheese cannot be achieved under different environmental-production conditions for two main reasons: (1) some milk features are linked to specific animal production systems; (2) cheese ripening is affected by the interaction between milk (specific) and the traditional technology applied to the transformation process (non-specific). Also, the environment for a good ripening stage can be quite specific and not reproducible. With reference to milk, factors of typicality are species and/or breed, pedoclimatic conditions, animal management system and feeding. Other factors that influence cheese quality are milk treatments, milk processing and the ripening procedures. The technology applied to most cheeses currently known as PDO utilizes only raw milk, rennet and natural lactic acid bacteria, so that milk must be, at its origin, suitable for processing. The specific milk characteristics that ensure a high success rate for PDO cheeses are high protein content and good renneting properties, appropriate fat content with appropriate fatty acid composition and the presence of chemical flavours originating from local feeds. Moreover, an appropriate microflora is also of major importance. The factors that contribute to achieving milk suitable for transformation into PDO cheese are genetics, age, lactation stage, season and climate, general management and health conditions, milking and particularly feeding, which affect nutrient availability, endocrine response and health status, and also the presence of microbes and chemical substances which enrich or reduce the milk-cheese quality. Many of these factors are regulated by the Producer Associations. However, the secret of the success of PDO cheeses is the combination of

  15. Influence of breed, milk production, season, and ambient temperature on dairy cow reticulorumen temperature.

    PubMed

    Liang, D; Wood, C L; McQuerry, K J; Ray, D L; Clark, J D; Bewley, J M

    2013-08-01

    Automatic monitoring of core body temperature in dairy cattle could be useful for identification of illness, heat stress, general physiological stress, and estrus. The SmartBolus (TenXSys Inc., Eagle, ID) system used a reticulorumen bolus to automatically record and transmit dairy cow temperatures. The objective of this research was to characterize the influence of milk yield (MY), time of day, breed, ambient temperature (AT), and season on reticulorumen temperatures (RT) in lactating dairy cows. Continuous RT and AT were collected by SmartBolus transponders every 15 min (96 records per d) from 93 cows (65 Holstein, 18 crossbred, and 10 Jersey) for 615 d. Mean (±SD) daily RT, AT, and MY were 40.14±0.32°C, 12.20±10.61°C, and 33.85±8.67 kg, respectively. The maximum and minimum RT were recorded at 2330 and 1000 h, respectively. Ambient temperature increased RT. Summer RT was significantly greater than spring, fall, or winter RT. The effect of MY on RT varied by breed, season, and AT. Crossbred RT was significantly lower than Holstein RT after adjusting for MY. Crossbred RT responded less to increasing AT than did Holstein RT, potentially indicating improved heat tolerance among these crossbred dairy cows. Reticulorumen temperature increased more dramatically for cows with greater milk yield as AT increased, demonstrating that high-producing cows are more susceptible to heat stress than low-producing cows. These results could be useful in interpretation of automatic temperature system data, heat stress management, and genetic selection of heat-tolerant cows. PMID:23769360

  16. Effects of farm management practices and environmental factors on bulk tank milk antibodies against gastrointestinal nematodes in dairy farms across Canada.

    PubMed

    Vanderstichel, Raphaël; Dohoo, Ian; Sanchez, Javier; Conboy, Gary

    2012-04-01

    Enzyme-linked immunosorbent assays (ELISAs) have been used as a diagnostic tool to quantify levels of gastrointestinal nematodes in dairy cattle by measuring Ostertagia ostertagi antibodies in milk. Higher levels of O. ostertagi antibodies measured by ELISA methods, referred to as optical density ratios (ODRs), are associated with decreased milk production in dairy cattle. On-farm management practices (e.g. pasturing techniques and anthelmintic usage) can influence the exposure of cattle to nematode infections and the magnitude of acquired worm burdens. Additionally, environmental and climatic factors, such as land elevation and precipitation, may also influence the levels of gastrointestinal parasitism. This repeated cross-sectional study investigated the effect of farm management practices and surrounding environmental factors on bulk tank (BT) ODRs in herds from provinces across Canada, and further examined the potential effects of various anthelmintic treatment protocols on BT ODRs. A total of 195 herds contributed an average of 3.5 BT samples between December 2003 and April 2005. The farm management practices were recorded from a questionnaire asking producers about their pasturing methods (confined, pastured, etc.), pasture sharing practices (e.g. mixing heifers with milking cows) and anthelmintic treatments. Environmental data were downloaded online from various governmental databases (e.g. Natural Resources Canada, Statistics Canada, Environment Canada, etc.). Statistical models, accounting for repeated measures (multiple BT ODRs for each farm) and for clustering of farms within a region (province or ecoregion), were used to analyze environmental and farm management data. Overall, the greater the exposure that heifers and milking cows had to pasture, the higher the levels of anti-parasite antibodies detected in BT samples. Treating the entire herd or treating milking cows at calving reduced BT ODR values. Farms in areas with higher number of rainy days

  17. Rat milk and dietary long arginine3 insulin-like growth factor I promote intestinal growth of newborn rat pups.

    PubMed

    Staley, M D; Gibson, C A; Herbein, J F; Grosvenor, C E; Baumrucker, C R

    1998-10-01

    Newborn rat pups were artificially reared by the pup in cup (PIC) method to determine whether dietary long arginine3 IGF-I (long R3 IGF-I), an IGF-I analog with high receptor affinity and low IGF binding protein (IGFBP) affinity, had efficacy on intestinal growth. IGF effects are mediated by IGFBP and receptor interactions, hence dietary-induced changes in intestinal IGF-II receptor patterns and IGFBP-3 message levels were investigated. Intestinal micrographs of pups fed rat milk replacer (RMR) for 3 d showed flattened villi with low cell counts and appeared similar to newborn intestines. Mother-fed (MF) controls and long R3 IGF-I-fed pups showed increased villi height and cell counts when compared with RMR pups, with long R3 IGF-I fed pups showing the greatest increase. At birth IGF-II-specific binding was not uniform in the intestine; specific binding was higher in the proximal intestinal section than in the distal intestinal section. However, after 3 d of MF treatment, specific binding had reversed and the distal section showed higher IGF-II-specific binding. Three days of RMR feeding did not change IGF-II-specific binding from that of the newborn pup. An IGFBP-3 message was identified in intestinal epithelium by in situ hybridization. Northern analysis of IGFBP-3 message showed a decline over time, but the change was not influenced by dietary treatments. In summary, milk-borne growth factors have the potential to affect intestinal growth within 3 d of treatment. PMID:9773839

  18. Dairy cattle serum and milk factors contributing to the risk of colon and breast cancers.

    PubMed

    zur Hausen, Harald; de Villiers, Ethel-Michele

    2015-08-15

    The analysis of published epidemiological data on colon and breast cancer reveals a remarkable concordance for most regions of the world. A low incidence for both cancers has been recorded in Mongolia and Bolivia. Discrepant data, however, have been reported for India, Japan and Korea. In India, the incidence of breast cancer is significantly higher than for colon cancer, in Japan and Korea colon cancer exceeds by far the rate of breast cancer. Here, studies are summarized pointing to a species-specific risk for colon cancer after consumption of beef originating from dairy cattle. Uptake of dairy products of Bos taurus-derived milk cattle, particularly consumed at early age, is suggested to represent one of the main risk factors for the development of breast cancer. A recent demonstration of reduced breast cancer rates in individuals with lactose intolerance (Ji et al., Br J Cancer 2014; 112:149-52) seems to be in line with this interpretation. Species-specific risk factors for these cancers are compatible with the transmission of different infectious factors transferred via meat or dairy products. Countries with discordant rates of colon and breast cancer reveal a similar discordance between meat and milk product consumption of dairy cattle. The recent isolation of a larger number of novel presumably viral DNAs from serum, meat and dairy products of healthy dairy cows, at least part of them infectious for human cells, deserves further investigation. Systemic infections early in life, resulting in latency and prevention of subsequent infections with the same agent by neutralizing antibodies, would require reconsideration of ongoing prospective studies conducted in the adult population. PMID:25648405

  19. Factors potentially influencing aminoglycoside use and expenditure

    SciTech Connect

    DiPiro, J.T.; Kilsdonk, G.F.; Amerson, A.B.; Record, K.E.

    1982-07-01

    Factors that may have influenced aminoglycoside use and expenditure in one hospital were examined. Factors that were evaluated as to their influence on aminoglycoside-use patterns were: (1) formulary status; (2) bacterial susceptibility patterns; (3) identified or perceived differences in toxicity; (4) changes in patient population; (5) price paid by the hospital for aminoglycosides; (6) distribution of newsletters or memoranda; (7) advertising and detailing; and (8) pharmacy policies. For FY 1976-77 to 1979-80, the largest proportion of aminoglycoside expense was for gentamicin. During FY 1980-81, the expenditure for gentamicin decreased and tobramycin accounted for the largest proportion of total expenditure. Monthly gentamicin use decreased 20% during FY 1980-81 from the previous year. Tobramycin use increased from January 1979 to November 1980 and decreased from December 1980 to June 1981. Kanamycin use and amikacin use were fairly constant during the study period. Based on temporal relationships, the following factors appeared to influence aminoglycoside use and expenditure: (1) a study conducted at the institution from June 1977 to June 1979 comparing gentamicin and tobramycin nephrotoxicity; (2) a comparative nephrotoxicity study published in a widely circulated medical journal in May 1980; and (3) an intramural newsletter and memorandum distributed in March 1981 encouraging selective aminoglycoside use. The identification of factors that potentially influenced aminoglycoside use can be used to anticipate the future impact of similar events and to devise strategies to influence antimicrobial use.

  20. Maternal risk factors associated with increased dioxin concentrations in breast milk in a hot spot of dioxin contamination in Vietnam.

    PubMed

    Anh, Nguyen Thi Nguyet; Nishijo, Muneko; Tai, Pham The; Maruzeni, Shoko; Morikawa, Yuko; Anh, Tran Hai; Van Luong, Hoang; Dam, Pham Minh; Nakagawa, Hideaki; Son, Le Ke; Nishijo, Hisao

    2014-01-01

    This study looked to identify determinants of exposure to dioxin in breast milk from breast-feeding women in a hot spot of dioxin exposure in Vietnam. Breast milk was collected from 140 mothers 1 month after delivery. The risk factors investigated included length of residency, drinking of well water and the frequency of animal food consumption. Cluster analysis was performed to identify dietary patterns of fish and meat portions, fish variety and egg variety. Residency, age and parity were clearly associated with increased dioxin levels. Drinking well water and the consumption of marine crab and shrimps were related to higher levels of furans in breast milk. The consumption of quail eggs also appeared to be associated with increased levels of some dioxin isomers in this area. Some mothers who ate no or less meat than fish and mothers who consumed more freshwater fish than marine fish had lower levels of dioxins in their breast milk. However, the type of water and the eating habits of mothers contributed only partly to the increased dioxin levels in their breast milk; the length of residency was the most important risk factor associated with increased dioxin body burdens of mothers. PMID:24149970

  1. Milk with and without lactoferrin can influence intestinal damage in a pig model of malnutrition.

    PubMed

    Garas, Lydia C; Feltrin, Cristiano; Hamilton, M Kristina; Hagey, Jill V; Murray, James D; Bertolini, Luciana R; Bertolini, Marcelo; Raybould, Helen E; Maga, Elizabeth A

    2016-02-01

    Malnutrition remains a leading contributor to the morbidity and mortality of children under the age of five worldwide. However, the underlying mechanisms are not well understood necessitating an appropriate animal model to answer fundamental questions and conduct translational research into optimal interventions. One potential intervention is milk from livestock that more closely mimics human milk by increased levels of bioactive components that can promote a healthy intestinal epithelium. We tested the ability of cow milk and milk from transgenic cows expressing human lactoferrin at levels found in human milk (hLF milk) to mitigate the effects of malnutrition at the level of the intestine in a pig model of malnutrition. Weaned pigs (3 weeks old) were fed a protein and calorie restricted diet for five weeks, receiving cow, hLF or no milk supplementation daily from weeks 3-5. After three weeks, the restricted diet induced changes in growth, blood chemistry and intestinal structure including villous atrophy, increased ex vivo permeability and decreased expression of tight junction proteins. Addition of both cow and hLF milk to the diet increased growth rate and calcium and glucose levels while promoting growth of the intestinal epithelium. In the jejunum hLF milk restored intestinal morphology, reduced permeability and increased expression of anti-inflammatory IL-10. Overall, this pig model of malnutrition mimics salient aspects of the human condition and demonstrates that cow milk can stimulate the repair of damage to the intestinal epithelium caused by protein and calorie restriction with hLF milk improving this recovery to a greater extent. PMID:26751615

  2. Analysis of cow factors influencing conception rates after two timed breeding protocols.

    PubMed

    Tenhagen, B A; Drillich, M; Heuwieser, W

    2001-09-15

    The objective of this study was to determine cow factors that influence conception rates after timed artificial insemination (TAI) on a commercial dairy farm. In Trial 1, 197 cows were synchronized by an administration of 25 mg of dinoprost between Days 48 and 54 post partum and again 14 days later. Cows were inseminated 66 and 90 hours after the second treatment. In Trial 2, 186 cows were treated with an Ovsynch protocol consisting of an administration of 0.02 mg of buserelin between Days 62 and 68 post partum, a treatment with 0.75 mg of tiaprost 7 days later and a second treatment with buserelin 48 h later. Cows were bred 16 to 20 hours after the last treatment. Cows with abnormal vaginal discharge at the time of insemination were excluded from AI. Lactation number, milk yield, fat and protein content of milk, signs of endometritis at an examination 14 to 20 days post partum and month of breeding were included as potential factors influencing conception on TAI. Conception rates after timed breeding were 32.0% and 30.6% in Trials 1 and 2, respectively. Logistic regression revealed that neither milk production parameters nor endometritis at post partum examination influenced conception rates in either of the two timed breeding protocols. Only parity showed an effect (P=0.012) in Trial 2. Primiparous cows were more likely to conceive after timed breeding than older cows (43.5 vs. 23.1%). An effect of parity, however, was not observed in Trial 1. It can be concluded that neither milk production nor endometritis at an examination 14 to 20 days post partum influence conception rates after TAI if cows with abnormal vulval discharge at the designated time of AI are excluded from breeding. PMID:11665885

  3. Case history: tracking the nutritional value of milk from a transitioning-to-organic dairy herd

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Research is focusing on many of the factors that influence the amounts of biologically active compounds (BACs) in milk, such as the influence of on-farm and seasonal factors, to improve the nutritional and health values of milk. In collaboration with the Rodale Institute, Kutztown, PA, our current s...

  4. Role of milk fat globule-epidermal growth factor 8 in osteoimmunology.

    PubMed

    Sinningen, Kathrin; Thiele, Sylvia; Hofbauer, Lorenz C; Rauner, Martina

    2016-01-01

    Milk fat globule-epidermal growth factor 8 (MFG-E8) is a glycoprotein that is abundantly expressed in various tissues and has a pivotal role in the phagocytic clearance of apoptotic cells. However, MFG-E8 has also gained significant attention because of its wide range of functions in autoimmunity, inflammation and tissue homeostasis. More recently, MFG-E8 has been identified as a critical regulator of bone homeostasis, being expressed in both, osteoblasts and osteoclasts. In addition, it was shown that MFG-E8 fulfils an active role in modulating inflammatory processes, suggesting an anti-inflammatory role of MFG-E8 and proposing it as a novel therapeutic target for inflammatory diseases. This concise review focusses on the expression and regulation of MFG-E8 in the context of inflammatory bone diseases, highlights its role in the pathophysiology of osteoimmune diseases and discusses the therapeutic potential of MFG-E8. PMID:27579162

  5. Factors Influencing the Fatigue Strength of Materials

    NASA Technical Reports Server (NTRS)

    Bollenrath, F

    1941-01-01

    A number of factors are considered which influence the static and fatigue strength of materials under practical operating conditions as contrasted with the relations obtaining under conditions of the usual testing procedure. Such factors are interruptions in operation, periodically fluctuating stress limits and mean stresses with periodic succession of several groups and stress states, statistical changes and succession of stress limits and mean stresses, frictional corrosion at junctures, and notch effects.

  6. Influence of milk-feeding type and genetic risk of developing coeliac disease on intestinal microbiota of infants: the PROFICEL study.

    PubMed

    Palma, Giada De; Capilla, Amalia; Nova, Esther; Castillejo, Gemma; Varea, Vicente; Pozo, Tamara; Garrote, José Antonio; Polanco, Isabel; López, Ana; Ribes-Koninckx, Carmen; Marcos, Ascensión; García-Novo, María Dolores; Calvo, Carmen; Ortigosa, Luis; Peña-Quintana, Luis; Palau, Francesc; Sanz, Yolanda

    2012-01-01

    Interactions between environmental factors and predisposing genes could be involved in the development of coeliac disease (CD). This study has assessed whether milk-feeding type and HLA-genotype influence the intestinal microbiota composition of infants with a family history of CD. The study included 164 healthy newborns, with at least one first-degree relative with CD, classified according to their HLA-DQ genotype by PCR-SSP DQB1 and DQA1 typing. Faecal microbiota was analysed by quantitative PCR at 7 days, and at 1 and 4 months of age. Significant interactions between milk-feeding type and HLA-DQ genotype on bacterial numbers were not detected by applying a linear mixed-model analysis for repeated measures. In the whole population, breast-feeding promoted colonization of C. leptum group, B. longum and B. breve, while formula-feeding promoted that of Bacteroides fragilis group, C. coccoides-E. rectale group, E. coli and B. lactis. Moreover, increased numbers of B. fragilis group and Staphylococcus spp., and reduced numbers of Bifidobacterium spp. and B. longum were detected in infants with increased genetic risk of developing CD. Analyses within subgroups of either breast-fed or formula-fed infants indicated that in both cases increased risk of CD was associated with lower numbers of B. longum and/or Bifidobacterium spp. In addition, in breast-fed infants the increased genetic risk of developing CD was associated with increased C. leptum group numbers, while in formula-fed infants it was associated with increased Staphylococcus and B. fragilis group numbers. Overall, milk-feeding type in conjunction with HLA-DQ genotype play a role in establishing infants' gut microbiota; moreover, breast-feeding reduced the genotype-related differences in microbiota composition, which could partly explain the protective role attributed to breast milk in this disorder. PMID:22319588

  7. Factors associated with total mercury concentrations in maternal blood, cord blood, and breast milk among pregnant women in Busan, Korea.

    PubMed

    Song, Yoojun; Lee, Chae-Kwan; Kim, Kun-Hyung; Lee, Jong-Tae; Suh, Chunhui; Kim, Se-Yeong; Kim, Jeong-Ho; Son, Byung-Chul; Kim, Dae-Hwan; Lee, Sangyoon

    2016-01-01

    This study investigated the concentration of total mercury (THg) in maternal blood, cord blood, and breast milk, and its association with dietary factors. A total of 127 pregnant women in Busan, Korea were recruited. Maternal blood, cord blood, and breast milk were collected at 36 weeks of gestation, at delivery, and at one week after birth, respectively. Information about dietary habits and other factors were obtained from each subject. The mean THg concentrations in maternal blood, cord blood, and breast milk were 3.12±1.36 μg/L, 5.46±2.41 μg/L, and 0.91±2.08 μg/L, respectively. Positive correlations were found between log-transformed THg concentrations in maternal blood and cord blood (r=0.829, p<0.001), and between maternal blood and breast milk (r=0.296, p=0.001). Multiple linear regression analysis showed that the log-transformed concentration of THg in maternal blood was positively correlated with fish consumption (β=0.345, p<0.0001) and negatively correlated with bean consumption (β=-0.055, p=0.048). Fish consumption (β=0.482, p<0.0001) and maternal age (β=0.025, p=0.033) were positively associated with the concentration of THg in cord blood, while negative correlations were found for bean consumption (β=-0.134, p=0.027) and parity (β=-0.172, p=0.015). Beef consumption (β=0.031, p=0.007) was positively associated with log-transformed THg concentrations in breast milk, while negative correlations were found for bean consumption (β=-0.019, p=0.003) and maternal age (β=-0.083, p=0.004). Our study found that both the dietary and demographic factors differently affected to THg concentrations among samples of maternal blood, cord blood, and breast milk. PMID:27222418

  8. Factors Influencing Employee Learning in Small Businesses

    ERIC Educational Resources Information Center

    Coetzer, Alan; Perry, Martin

    2008-01-01

    Purpose: The purpose of this research is to identify key factors influencing employee learning from the perspective of owners/managers. Design/methodology/research: Data were gathered from owners/managers in a total of 27 small manufacturing and services firms through interviews and analysed using content analytic procedures. Findings: The…

  9. Factors Influencing High School Students' Career Aspirations

    ERIC Educational Resources Information Center

    Tang, Mei; Pan, Wei; Newmeyer, Mark D.

    2008-01-01

    This article explores the factors influencing high school students' career aspirations with a study analyzing 141 high school students. The Social Cognitive Career Development Model was utilized to examine the interactive relationships among learning experiences, career self-efficacy, outcome expectations, career interests, and career choices. The…

  10. Factors Influencing Learning at a Community College.

    ERIC Educational Resources Information Center

    Johnson, Marvin L.

    The Walberg Educational Productivity Model theorizes that learning in its affective, behavioral, and cognitive aspects is causally influenced by factors in the areas of individual aptitude (i.e., prior achievement, age or stage of maturation, and motivation), instructional treatment (i.e., quantity of time spent in learning situations and…

  11. Factors Influencing the Successful Introduction of Portfolios

    ERIC Educational Resources Information Center

    Van Tartwijk, Jan; Driessen, Erik; Van Der Vleuten, Cees; Stokking, Karel

    2007-01-01

    Factors influencing the successful introduction of portfolios are described. A portfolio is a purposeful collection of all kinds of documents and other artefacts that together give an impression of how tasks were fulfilled and how competence has developed. A portfolio can also contain reflections and plans for future development. Although…

  12. Technology Education Graduate Education: Factors Influencing Participation.

    ERIC Educational Resources Information Center

    Cardon, Phillip L.; Rogers, George E.

    A modified Delphi technique was used to identify the factors that positively influence technology education teachers' decision to enroll in graduate education programs and the barriers to their enrollment in advanced degree programs. Two pairs of Delphi panels were established. The doctoral panels consisted of 15 recent doctoral graduates and 30…

  13. Factors Influencing Teaching Choice in Turkey

    ERIC Educational Resources Information Center

    Kilinc, Ahmet; Watt, Helen M. G.; Richardson, Paul W.

    2012-01-01

    Why choose to become a teacher in Turkey? The authors examined motivations and perceptions among preservice teachers (N = 1577) encompassing early childhood, primary and secondary education. The Factors Influencing Teaching Choice (FIT-Choice) instrument was translated into Turkish and its construct validity and reliability assessed. Altruistic…

  14. Social Factors Influencing Child Health in Ghana

    PubMed Central

    Quansah, Emmanuel; Ohene, Lilian Akorfa; Norman, Linda; Mireku, Michael Osei; Karikari, Thomas K.

    2016-01-01

    Objectives Social factors have profound effects on health. Children are especially vulnerable to social influences, particularly in their early years. Adverse social exposures in childhood can lead to chronic disorders later in life. Here, we sought to identify and evaluate the impact of social factors on child health in Ghana. As Ghana is unlikely to achieve the Millennium Development Goals’ target of reducing child mortality by two-thirds between 1990 and 2015, we deemed it necessary to identify social determinants that might have contributed to the non-realisation of this goal. Methods ScienceDirect, PubMed, MEDLINE via EBSCO and Google Scholar were searched for published articles reporting on the influence of social factors on child health in Ghana. After screening the 98 articles identified, 34 of them that met our inclusion criteria were selected for qualitative review. Results Major social factors influencing child health in the country include maternal education, rural-urban disparities (place of residence), family income (wealth/poverty) and high dependency (multiparousity). These factors are associated with child mortality, nutritional status of children, completion of immunisation programmes, health-seeking behaviour and hygiene practices. Conclusions Several social factors influence child health outcomes in Ghana. Developing more effective responses to these social determinants would require sustainable efforts from all stakeholders including the Government, healthcare providers and families. We recommend the development of interventions that would support families through direct social support initiatives aimed at alleviating poverty and inequality, and indirect approaches targeted at eliminating the dependence of poor health outcomes on social factors. Importantly, the expansion of quality free education interventions to improve would-be-mother’s health knowledge is emphasised. PMID:26745277

  15. The effects of milking frequency on insulin-like growth factor I signaling within the mammary gland of dairy cows.

    PubMed

    Murney, R; Stelwagen, K; Wheeler, T T; Margerison, J K; Singh, K

    2015-08-01

    In dairy cows, short-term changes in milking frequency (MF) in early lactation have been shown to produce both an immediate and a long-term effect on milk yield. The effect of MF on milk yield is controlled locally within mammary glands and could be a function of changes in either number or activity of secretory mammary epithelial cells (MEC). Insulin-like growth factor I (IGF-I) signaling is one candidate factor that could mediate these effects, as it can be controlled locally within mammary glands. Both MEC number and activity can be affected by IGF-I signaling by activating the phosphoinositide 3-kinase (PI3K)/Akt and extracellular-signal-regulated kinase (ERK)1/2 pathways. To investigate the relationship between MF and IGF-I signaling, udder halves of 17 dairy cows were milked either 4 times a day (4×) or once a day (1×) for 14 d in early lactation. On d 14, between 3 and 5 h following milking, mammary biopsies were obtained from 10 cows from both udder halves, and changes in the expression of genes associated with IGF-I signaling and the activation of the PI3K/Akt and ERK1/2 pathways were measured. The mRNA abundance of IGF type I receptor, IGF binding protein (IGFBP)-3, and IGFBP-5 were lower following 4× milking relative to 1× milking. However, the mRNA abundance of IGF-I was not affected by MF. Both IGFBP3 and IGFBP5 are thought to inhibit IGF-I; therefore, decreases in their mRNA abundance may serve to stimulate the IGF-I signal in the 4×-milked mammary gland. The activation of PI3K/Akt pathway was lower in response to 4× milking relative to 1×, and the activation of the ERK1/2 was unaffected by MF, suggesting that they do not mediate the effects of MF. PMID:26074231

  16. Factors that influence women's dispositions toward science

    NASA Astrophysics Data System (ADS)

    Atria, Catherine Graczyk

    Females have been underrepresented in the study of science and science careers for decades although advancements have been made in closing this gender gap, the gap persists particularly in the physical sciences. Variables which influence a woman's desire to pursue and maintain a science course of study and career must be discovered. The United States lags behind other industrialized countries in the fields of science, math, and engineering. Females comprise an estimated half of the population; their potential contributions cannot be ignored or overlooked. This retrospective research study explores the personal experiences of ten women enrolled in science majors, with science related career plans. The goal of this study is to describe the factors that influence the participants' interest in science. The findings, the effect of science coursework, science teachers' personality and manner, other influential educational personnel, role models and mentors, external influences exclusive of school, parental influence, locus of control and positive attitudes toward science confirm what other researchers have found.

  17. Influence of diet and rennet on the composition of goats' milk and cheese.

    PubMed

    Fresno Baquero, María; Álvarez Ríos, Sergio; Rodríguez Rodríguez, Elena; Díaz Romero, Carlos; Darias Martín, Jacinto

    2011-05-01

    Dry matter, protein, fat, pH, mineral (Na, K, Ca and Mg) and trace elements (Fe, Cu, Zn and Se) concentrations were determined in samples of goats' milk and in fresh, semi-hard and hard cheeses to study the effect of the goats' diet and the type of rennet used for the cheese processing of the Palmero Protected Designation of Origin cheeses. Two groups of 20 Palmero goats were fed 2 different diets: a Palmero diet (PD supplied by native forages adapted to subhumid areas, which had a high ratio of long fibre to concentrates (65:35), and an actual diet (AD), the most commonly used by goat farmers, with a low ratio of long fibre to concentrates (35:65). In general, the cheese samples from goats fed with PD had higher mean Ca, Zn, Cu and Se concentrations than the samples obtained from AD fed goats. The diet exhibited a greater influence on the chemical composition of the cheeses than the rennet used in their production. Applying a stepwise linear discriminant analysis a complete percentage of correct classifications of the three types of cheeses according to the diet of the goats was observed. PMID:24725675

  18. A Water Availability Intervention in New York City Public Schools: Influence on Youths’ Water and Milk Behaviors

    PubMed Central

    Mijanovich, Tod; Abrams, Courtney; Cantor, Jonathan; Dunn, Lillian; Nonas, Cathy; Cappola, Kristin; Onufrak, Stephen; Park, Sohyun

    2015-01-01

    Objectives. We determined the influence of “water jets” on observed water and milk taking and self-reported fluid consumption in New York City public schools. Methods. From 2010 to 2011, before and 3 months after water jet installation in 9 schools, we observed water and milk taking in cafeterias (mean 1000 students per school) and surveyed students in grades 5, 8, and 11 (n = 2899) in the 9 schools that received water jets and 10 schools that did not. We performed an observation 1 year after implementation (2011–2012) with a subset of schools. We also interviewed cafeteria workers regarding the intervention. Results. Three months after implementation we observed a 3-fold increase in water taking (increase of 21.63 events per 100 students; P < .001) and a much smaller decline in milk taking (-6.73 events per 100 students; P = .012), relative to comparison schools. At 1 year, relative to baseline, there was a similar increase in water taking and no decrease in milk taking. Cafeteria workers reported that the water jets were simple to clean and operate. Conclusions. An environmental intervention in New York City public schools increased water taking and was simple to implement. PMID:25521867

  19. Influence of milk source on transplantability of histocompatible mammary tumours in mice.

    PubMed Central

    Oth, D.; Sabolovic, D.

    1977-01-01

    It is confirmed that C3H mammary tumours are much more easily transplantable in histocompatible recipients when these have been reared on C3H milk, than when they have been reared on milk from the inbred Swiss/B strain. By contrast, A.CA mammary tumours transplanted in histocompatible hosts reared on A.CA or Swiss/B milk, grow almost equally well in both sorts of recipient. Thus, rearing on Swiss/B milk has different effects on the transplantability of mammary tumours of C3H and A.CA. On the other hand, recipients which were reared on C3H or A.CA milks accept grafts of C3H mammary tumours about equally, suggesting that milks from A.CA and C3H have the same effect on the transplantability of C3H mammary tumours. The different action of Swiss/B milk on tumours of C3H and A.CA seems best attributed to differences between C3H and A.CA tumours or between mouse strain genotypes. By contrast, the transplantability of C3H mammary tumours is significantly changed when the recipients were reared on milk from the RIII strain instead of C3H. These facts suggest that the milk from RIII has an action which differs from that of both C3H and A.CA in this respect. The data are discussed on the basis of a differential tollerance-inducing action of mammary tumour viruses (MTVs) which infect C3H, A.CA and RIII, and have an important role in tumour induction. PMID:326285

  20. Factors Influencing Seminar Learning and Academic Achievement.

    PubMed

    Spruijt, Annemarie; Leppink, Jimmie; Wolfhagen, Ineke; Bok, Harold; Mainhard, Tim; Scherpbier, Albert; van Beukelen, Peter; Jaarsma, Debbie

    2015-01-01

    Many veterinary curricula use seminars, interactive educational group formats in which some 25 students discuss questions and issues relating to course themes. To get indications on how to optimize the seminar learning process for students, we aimed to investigate relationships between factors that seem to be important for the seminar learning process, and to determine how these seminar factors account for differences in students' achievement scores. A 57-item seminar evaluation (USEME) questionnaire was administered to students right after they attended a seminar. In total, 80 seminars distributed over years 1, 2, and 3 of an undergraduate veterinary medicine curriculum were sampled and 988 questionnaires were handed in. Principal factor analysis (PFA) was conducted on 410 questionnaires to examine which items could be grouped together as indicators of the same factor, and to determine correlations between the derived factors. Multilevel regression analysis was performed to explore the effects of these seminar factors and students' prior achievement scores on students' achievement scores. Within the questionnaire, four factors were identified that influence the seminar learning process: teacher performance, seminar content, student preparation, and opportunities for interaction within seminars. Strong correlations were found between teacher performance, seminar content, and group interaction. Prior achievement scores and, to a much lesser extent, the seminar factor group interaction appeared to account for differences in students' achievement scores. The factors resulting from the present study and their relation to the method of assessment should be examined further, for example, in an experimental setup. PMID:26075625

  1. Influence of organizational factors on safety

    SciTech Connect

    Haber, S.B.; Metlay, D.S.; Crouch, D.A.

    1990-01-01

    There is a need for a better understanding of exactly how organizational management factors at a nuclear power plant (NPP) affect plant safety performance, either directly or indirectly, and how these factors might be observed, measured, and evaluated. The purpose of this research project is to respond to that need by developing a general methodology for characterizing these organizational and management factors, systematically collecting information on their status and integrating that information into various types of evaluative activities. Research to date has included the development of the Nuclear Organization and Management Analysis Concept (NOMAC) of a NPP, the identification of key organizational and management factors, and the identification of the methods for systematically measuring and analyzing the influence of these factors on performance. Most recently, two field studies, one at a fossil fuel plant and the other at a NPP, were conducted using the developed methodology. Results are presented from both studies highlighting the acceptability, practicality, and usefulness of the methods used to assess the influence of various organizational and management factors including culture, communication, decision-making, standardization, and oversight. 6 refs., 3 figs., 1 tab.

  2. Political and economic factors influencing contraceptive uptake.

    PubMed

    Sai, F T

    1993-01-01

    International, national and local level politics influence the uptake of contraception through consensuses, laws, financial and moral support or the creation of an enabling atmosphere. Opposition to contraception generally comes from some churches and groups opposed to particular technologies. Socio-economic factors, particularly education, the health care system and the perceived or actual cost of fertility regulation as compared to benefits expected from children also powerfully influence contraceptive use. For many poor women in developing countries their powerlessness in relation to their male partners is an important obstacle. PMID:8324609

  3. Influencing factor on the prognosis of arthrocentesis

    PubMed Central

    Kim, Yoon Ho; Jeong, Tae Min; Pang, Kang Mi

    2014-01-01

    Objectives The purpose of this article is to evaluate factors influencing prognosis of arthrocentesis in patients with temporomandibular joint (TMJ) disorder. Materials and Methods The subjects included 145 patients treated with arthrocentesis at the Dental Center of Ajou University Hospital from 2011 to 2013 for the purpose of recovering mouth opening limitation (MOL) and pain relief. Prognosis of arthrocentesis was evaluated 1 month after the operation. Improvement on MOL was defined as an increase from below 30 mm (MOL ≤30 mm) to above 40 mm (MOL ≥40 mm), and pain relief was defined as when a group with TMJ pain with a visual analog scale (VAS) score of 4 or more (VAS ≥4) decreased to a score of 3 or more. The success of arthrocentesis was determined when either mouth opening improved or pain relief was fulfilled. To determine the factors influencing the success of arthrocentesis, the patients were classified by age, gender, diagnosis group (the anterior disc displacement without reduction group, the anterior disc displacement with reduction group, or other TMJ disorders group), time of onset and oral habits (clenching, bruxism) to investigate the correlations between these factors and prognosis. Results One hundred twenty out of 145 patients who underwent arthrocentesis (83.4%) were found to be successful. Among the influencing factors mentioned above, age, diagnosis and time of onset had no statistically significant correlation with the success of arthrocentesis. However, a group of patients in their fifties showed a lower success rate (ANOVA P=0.053) and the success rate of the group with oral habits was 71% (Pearson's chi-square test P=0.035). Conclusion From this study, we find that factors influencing the success of arthrocentesis include age and oral habits. We also conclude that arthrocentesis is effective in treating mouth opening symptoms and for pain relief. PMID:25247144

  4. Somatic Cell Counts in Bovine Milk

    PubMed Central

    Dohoo, I. R.; Meek, A. H.

    1982-01-01

    Factors which influence somatic cell counts in bovine milk are reviewed and guidelines for their interpretation are presented. It is suggested that the thresholds of 300 000 and 250 000 cells/mL be used to identify infected quarters and cows respectively. However, it is stressed that somatic cell counts are general indicators of udder health which are subject to the influence of many factors. Therefore the evaluation of several successive counts is preferable to the interpretation of an individual count. Relationships between somatic cell counts and both milk production and milk composition are discussed. Subclinical mastitis reduces milk quality and decreases yield although the relationship between production loss and somatic cell count requires clarification. Finally the availability of somatic cell counting programs in Canada is presented. PMID:17422127

  5. Factors influencing permanent teeth eruption. Part one--general factors.

    PubMed

    Almonaitiene, Ruta; Balciuniene, Irena; Tutkuviene, Janina

    2010-01-01

    Variation in the normal eruption of teeth is a common finding, but significant deviation from established norms should alert the clinician to take some diagnostic procedures in order to evaluate patient health and development. Disturbance in tooth eruption time could be a symptom of general condition or indication of altered physiology and craniofacial development. The aim of this review is to analyze general factors that could influence permanent teeth eruption. The articles from 1965 to 2009 in English related to topic were identified. 84 articles were selected for data collection. Although permanent teeth eruption is under significant genetic control, various general factors such as gender, socioeconomic status, craniofacial morphology, body composition can influence this process. Most significant disturbance in teeth emergence is caused by systemic diseases and syndromes. PMID:21063135

  6. Electrolyte-free milk protein solution influences sodium and fluid retention in rats.

    PubMed

    Ishihara, Kengo; Kato, Yoshiho; Usami, Ayako; Yamada, Mari; Yamamura, Asuka; Fushiki, Tohru; Seyama, Yousuke

    2013-01-01

    Milk is an effective post-exercise rehydration drink that maintains the net positive fluid balance. However, it is unclear which components are responsible for this effect. We assessed the effect of milk protein solution (MPS) obtained by dialysis on body fluid retention. Milk, MPS, milk electrolyte solution (MES), sports drink and water were administered to male Wistar rats at a dose of 6 ml/rat after treadmill exercise. Total body fluid retention was assessed by urine volume 4 h after administration of hydrating liquids. The rate of gastric emptying was evaluated by a tracer method using (13)C-labelled acetate. Plasma osmolality, Na and K levels, and urinary Na and K were measured by HPLC and osmometry, respectively. The gastric emptying rate was not delayed by MPS. During 4 h of rehydration, cumulative urine volumes differed significantly between treatment groups (P < 0·05) with 4·9, 2·2 and 3·4 ml from water-, milk- and MPS-fed rats, respectively. Thus, MPS elicited 50 % of the total body fluid retention of milk. Plasma aldosterone levels were significantly higher in MPS- and milk-fed rats compared with water-fed rats. Plasma osmolality was maintained at higher levels in MPS-fed rats than in water- and MES-fed rats (P < 0·05). Cumulative urine Na excretion was also suppressed in the milk- and MPS-fed groups compared with the MES-fed group. Our results demonstrate that MPS obtained by dialysis clearly affects net body water balance without affecting gastric emptying after exercise. This effect was attributed to retention of Na and water, and maintenance of plasma osmolality. PMID:25191594

  7. Cupuassu (Theobroma grandiflorum) pulp, probiotic, and prebiotic: Influence on color, apparent viscosity, and texture of goat milk yogurts.

    PubMed

    Costa, Marion P; Frasao, Beatriz S; Silva, Adriana Cristina O; Freitas, Mônica Q; Franco, Robson M; Conte-Junior, Carlos A

    2015-09-01

    Cupuassu is an acidic fruit that has a characteristic aroma, flavor, and texture; its fiber-rich pulp can provide a different consistency than other fruit pulps. Goat milk is an excellent source of amino acids, fatty acids, and minerals, and is widely used for processing fermented milks, such as yogurt. However, compared with cow milk yogurts, it is difficult to make goat milk yogurts with a good consistency. Therefore, it is necessary to use certain technological strategies. This study was carried out to investigate the possibility of adding cupuassu pulp, probiotic (Lactobacillus acidophilus LA-5), and prebiotic (inulin) to improve the texture of goat milk yogurt. A total of 6 treatments were performed: natural (N), probiotic (Pro), prebiotic (Pre), synbiotic (S), cupuassu (C), and probiotic with cupuassu (PC). The viability of probiotic in yogurts (Pro, S, and PC) was evaluated. In addition, instrumental analyses (pH, color, apparent viscosity, and texture) were performed to evaluate the influence of these different ingredients on goat milk yogurts. The probiotic bacteria remained viable (≥7 log cfu·mL(-1)) throughout the 28d of refrigerated storage, which exceeded the minimum count required to confer probiotic physiological benefits. The pH levels of the yogurts inoculated with L. acidophilus (Pro, S, and PC) were lower than others yogurts (N, Pre, and C). However, all yogurt samples underwent gradual decreases in pH until 7 to 14d of storage. The lightness (L*) was affected initially by addition of all ingredients (cupuassu pulp, probiotic, and prebiotic). The addition of cupuassu pulp (C and PC) increased the L* during the period of storage. Apparent viscosity and firmness decreased in the PC yogurt. The consistency was highest in the yogurts with added prebiotic (Pre and S) than the other yogurts (N, Pro, C, and PC) at the end of the storage period (d 28). The cohesiveness remained constant in all yogurts (N, Pro, Pre, S, C, and PC). Based on the results

  8. Breast milk protects against the development of necrotizing enterocolitis through inhibition of Toll Like Receptor 4 in the intestinal epithelium via activation of the epidermal growth factor receptor

    PubMed Central

    Good, Misty; Sodhi, Chhinder P.; Egan, Charlotte E.; Afrazi, Amin; Jia, Hongpeng; Yamaguchi, Yukihiro; Lu, Peng; Branca, Maria F.; Ma, Congrong; Prindle, Thomas; Mielo, Samantha; Pompa, Anthony; Hodzic, Zerina; Ozolek, John A.; Hackam, David J.

    2015-01-01

    Breast milk is the most effective strategy to protect infants against necrotizing enterocolitis (NEC), a devastating disease which is characterized by severe intestinal necrosis. Previous studies have demonstrated that the lipopolysaccharide receptor toll-like receptor 4 (TLR4) plays a critical role in NEC development via deleterious effects on mucosal injury and repair. We now hypothesize that breast milk protects against NEC by inhibiting TLR4 within the intestinal epithelium, and sought to determine the mechanisms involved. Breast milk protected against NEC and reduced TLR4 signaling in wild-type neonatal mice, but not in mice lacking the epidermal growth factor receptor (EGFR), while selective removal of EGF from breast milk reduced its protective properties, indicating that breast milk inhibits NEC and attenuates TLR4 signaling via EGF/EGFR activation. Over-expression of TLR4 in the intestinal epithelium reversed the protective effects of breast milk. The protective effects of breast milk occurred via inhibition of enterocyte apoptosis and restoration of enterocyte proliferation. Importantly, in IEC-6 enterocytes, breast milk inhibited TLR4 signaling via inhibition of GSK3β. Taken together, these findings offer mechanistic insights into the protective role for breast milk in NEC, and support a link between growth factor and innate immune receptors in NEC pathogenesis. PMID:25899687

  9. Contextualizing online human milk sharing: structural factors and lactation disparity among middle income women in the U.S.

    PubMed

    Palmquist, Aunchalee E L; Doehler, Kirsten

    2014-12-01

    Women in the U.S. face significant structural constraints in attempting to breastfeed as recommended in the first six months of their child's life. Internet-facilitated human milk sharing is an emergent response to breastfeeding challenges. Little is known about the demographic characteristics of milk sharing donors and recipients and the ways structural factors circumscribe the biocultural context of lactation in milk sharing practices. Data regarding demographic characteristics, reproductive history, lactation history, and levels of social support and health care provider support for breastfeeding were collected via an online survey September 2013-March 2014. Statistical tests were executed to ascertain whether significant differences exist between donors and recipients. A total of 867 respondents (661 donors, 206 recipients) met the eligibility criteria for the study. Respondents were U.S. residents and primarily White, middle-class, well educated, and employed women. Both donors and recipients reported higher than the national average for household income, maternal educational attainment, breastfeeding exclusivity 0-6 months, and breastfeeding duration. Differences in lactation sufficiency and breastfeeding outcomes between donors and recipients were associated with both structural and biocultural factors. Donors reported significantly higher income, education, and support for breastfeeding from spouse/partner, other family, employers, and pediatricians. Donors also reported significantly higher rates of full term birth for child of most recent lactation. This study provides a foundation for understanding how milk sharing reflects a broader political economy of breastfeeding in the U.S. PMID:25441326

  10. Chemical contaminants in human milk: an overview.

    PubMed Central

    Sonawane, B R

    1995-01-01

    This review contains a succinct overview of the nature and extent of the problem of contamination of human milk with environmental and occupational chemicals, excluding drugs. Factors influencing the levels of contaminants in breast milk are discussed. Also, data on major chemicals of concern with potential health risk(s) to the general population and risk-benefit considerations are dealt with briefly. Based on the available data on the subject, research needs have been identified and policy recommendations are suggested. PMID:8549474

  11. Cow- and farm-level risk factors for lameness on dairy farms with automated milking systems.

    PubMed

    Westin, R; Vaughan, A; de Passillé, A M; DeVries, T J; Pajor, E A; Pellerin, D; Siegford, J M; Witaifi, A; Vasseur, E; Rushen, J

    2016-05-01

    Lameness is a major concern to animal health and welfare within the dairy industry. Our objectives were to describe the prevalence of lameness in high-producing cows on farms with automated milking systems (AMS) and to identify the main risk factors for lameness at the animal and farm level. We visited 36 AMS farms across Canada and Michigan. Farm-level factors related to stall design, bedding use, flooring, and stocking rates were recorded by trained observers. Cows were scored for lameness, leg injuries, body condition (BCS), and body size (hip width and rump height; n=1,378; 25-40 cows/farm). Mean herd prevalence of clinical lameness was 15% (range=2.5-46%). Stall width relative to cow size and parity was found to be the most important factor associated with lameness. Not fitting the average stall width increased the odds of being lame 3.7 times in primiparous cows. A narrow feed alley [<430cm; odds ratio (OR)=1.9], obstructed lunge space (OR=1.7), a low BCS (OR=2.1 for BCS ≤2.25 compared with BCS 2.75-3.0), and presence of hock lesions (OR=1.6) were also identified as important risk factors for lameness. Only 1 of 36 farms had stalls of adequate width and length for the cows on their farm. For lameness prevention, it can be concluded that more emphasis needs be placed on either building stalls of appropriate width or selecting for smaller-framed cows that fit the existing stalls. PMID:26923045

  12. Glucose transporter expression differs between bovine monocyte and macrophage subsets and is influenced by milk production.

    PubMed

    Eger, M; Hussen, J; Koy, M; Dänicke, S; Schuberth, H-J; Breves, G

    2016-03-01

    The peripartal period of dairy cows is characterized by negative energy balance and higher incidences of infectious diseases such as mastitis or metritis. With the onset of lactation, milk production is prioritized and large amounts of glucose are transported into the mammary gland. Decreased overall energy availability might impair the function of monocytes acting as key innate immune cells, which give rise to macrophages and dendritic cells and link innate and adaptive immunity. Information on glucose requirements of bovine immune cells is rare. Therefore, this study aims to evaluate glucose transporter expression of the 3 bovine monocyte subsets (classical, intermediate, and nonclassical monocytes) and monocyte-derived macrophages and to identify influences of the peripartal period. Blood samples were either collected from nonpregnant healthy cows or from 16 peripartal German Holstein cows at d -14, +7, and +21 relative to parturition. Quantitative real-time PCR was applied to determine mRNA expression of glucose transporters (GLUT) 1, GLUT3, and GLUT4 in monocyte subsets and monocyte-derived macrophages. The low GLUT1 and GLUT3 expression in nonclassical monocytes was unaltered during differentiation into macrophages, whereas in classical and intermediate monocytes GLUT expression was downregulated. Alternatively activated M2 macrophages consumed more glucose compared with classically activated M1 macrophages. The GLUT4 mRNA was only detectable in unstimulated macrophages. Neither monocytes nor macrophages were insulin responsive. In the peripartum period, monocyte GLUT1 and GLUT3 expression and the GLUT3/GLUT1 ratio were negatively correlated with lactose production. The high-affinity GLUT3 transporter appears to be the predominant glucose transporter on bovine monocytes and macrophages, especially in the peripartal period when blood glucose levels decline. Glucose transporter expression in monocytes is downregulated as a function of lactose production, which

  13. Precalving and early lactation factors that predict milk casein and fertility in the transition dairy cow.

    PubMed

    Rodney, Rachael M; Hall, Jenianne K; Westwood, Charlotte T; Celi, Pietro; Lean, Ian J

    2016-09-01

    Multiparous Holstein cows (n=82) of either high or low genetic merit (GM) (for milk fat + protein yield) were allocated to 1 of 2 diets in a 2×2 factorial design. Diets differed in the ratio of rumen-undegradable protein (RUP) to rumen-degradable protein (37% RUP vs. 15% RUP) and were fed from 21 d precalving to 150 days in milk. This study evaluated the effects of these diets and GM on concentrations of milk casein (CN) variants and aimed to identify precalving and early lactation variables that predict milk CN and protein yield and composition and fertility of dairy cows. It explored the hypothesis that low milk protein content is associated with lower fertility and extended this hypothesis to also evaluate the association of CN contents with fertility. Yields (kg/d) for CN variants were 0.49 and 0.45 of α-CN, 0.38 and 0.34 of β-CN, 0.07 and 0.06 for κ-CN, and 0.10 and 0.09 of γ-CN for high- and low-RUP diets, respectively. Increased RUP increased milk, CN, and milk protein yields. Increased GM increased milk protein and γ-CN yields and tended to increase milk CN yield. The effects of indicator variables on CN variant yields and concentrations were largely consistent, with higher body weight and α-amino nitrogen resulting in higher yields, but lower concentrations. An increase in cholesterol was associated with decreased CN variant concentrations, and disease lowered CN variant yield. A diet high in RUP increased proportion of first services that resulted in pregnancy from 41 to 58%. Increased precalving metabolizable protein (MP) balance decreased the proportion of first services that resulted in pregnancy when evaluated in a model containing CN percentage, milk protein yield, diet, and GM. This finding suggests that the positive effects of increasing dietary RUP on fertility may be curvilinear because cows with a very positive MP balance before calving were less fertile than those with a lower, but positive, MP balance. Prepartum MP balance was important

  14. Oligosaccharide Composition of Breast Milk Influences Survival of Uninfected Children Born to HIV-Infected Mothers in Lusaka, Zambia12

    PubMed Central

    Kuhn, Louise; Kim, Hae-Young; Hsiao, Lauren; Nissan, Caroline; Kankasa, Chipepo; Mwiya, Mwiya; Thea, Donald M; Aldrovandi, Grace M; Bode, Lars

    2015-01-01

    Background: Human milk oligosaccharides (HMOs) have multiple immunomodulatory functions that influence child health. Objective: In this study we investigated whether HMO composition influences survival to 2 y of age in HIV-infected and HIV-exposed, uninfected (HEU) children during and after breastfeeding. Methods: In the context of an early weaning trial in 958 HIV-infected women in Lusaka, Zambia, we conducted a nested case-cohort analysis of mortality to 2 y of age among 103 HIV-infected and 143 HEU children. Breast-milk samples collected at 1 mo postpartum were analyzed for HMO content. Samples were selected to include mothers of all HIV-infected children detected by 6 wk of age, of whom 63 died at <2 y of age; mothers of all HEU children who died at <2 y of age (n = 66); and a random sample of 77 HEU survivors. Associations before and after weaning in HIV-infected and HEU infants separately were investigated by using Cox models. Results: Among HEU children, higher maternal breast-milk concentrations of 2-linked fucosylated HMOs [2′-fucosyllactose and lacto-N-fucopentaose (LNFP) I] (HR: 0.33; 95% CI: 0.14, 0.74) as well as non–2-linked fucosylated HMOs (3-fucosyllactose and LNFP II/III; HR: 0.28; 95% CI: 0.13, 0.67) were significantly associated with reduced mortality during, but not after, breastfeeding after adjustment for confounders. Breastfeeding was protective against mortality only in HEU children with high concentrations of fucosylated HMOs. Among HIV-infected children, no consistent associations between HMOs and mortality were observed, but breastfeeding was protective against mortality. Conclusions: The oligosaccharide composition of breast milk may explain some of the benefits of breastfeeding in HEU children. HIV infection may modulate some of the consequences of HMOs on child survival. PMID:25527660

  15. Factors influencing union formation in Nairobi, Kenya.

    PubMed

    Bocquier, Philippe; Khasakhala, Anne

    2009-07-01

    Using retrospective data from the Urban Integration Survey conducted in 2001 in Nairobi, Kenya, on a sample of 955 women and men aged 25-54, this paper compares factors influencing entry into union formation for men and women. The analysis uses event history methods, specifically Cox Proportional Hazards regression, stratified by age cohort and run separately by sex. The results indicate that delay in union formation is more pronounced for women than for men. Cohabitation without formal marriage is the prominent form of union, especially among the younger generation, and appears to have increased. For men, the timing of union is more dependent upon human capital acquisition than on cultural factors. These findings show that the marriage search model, which was first applied in Western countries, can also hold in cities of developing countries. Nonetheless, neither the search model nor the integration or the independence models apply to women's union formation, which very few exogenous factors can explain. PMID:19250585

  16. Influence of different systems for feeding supplements to grazing dairy cows on milk fatty acid composition.

    PubMed

    Akbaridoust, Ghazal; Plozza, Tim; Trenerry, Victor C; Wales, William J; Auldist, Martin J; Dunshea, Frank R; Ajlouni, Said

    2014-05-01

    This study investigated the effects of different strategies for feeding supplements to grazing dairy cows on the proportions of fatty acids in milk. Two hundred and sixteen cows were fed supplementary grain and forage according to one of 3 different strategies; (1) CONTROL: cows grazed perennial ryegrass pasture (14 kg dry matter/d) supplemented with milled barley grain fed in the milking parlour and pasture silage offered in the paddock; (2) Partial mixed ration 1 (PMR1): same pasture allotment and supplement as CONTROL strategy, but the supplements presented as a mixed ration after each milking in feedpad, and; (3) Partial mixed ration 2 (PMR2): same pasture allotment, supplemented with a mixed ration of milled barley grain, alfalfa hay, corn silage and crushed corn grain fed in a feedpad. Within each strategy, cows were assigned to receive either 6, 8, 10 or 12 kg dry matter supplement/cow per d. Milk fatty acid proportions from cows fed CONTROL and PMR1 strategies were similar and different from those fed PMR2, particularly at 10 to 12 kg dry matter supplement/cow per d. The reduction in milk fat yield and concentration in cows fed high amounts of supplement as CONTROL and PMR1 was coincident with 4 × increase in 10t-18:1 proportion. The composition of the partial mixed ration (PMR) and the amount offered affected milk fatty acid proportions and milk fat content, however, the method of supplementation did not. PMID:24560061

  17. Bacillus cereus spores during housing of dairy cows: factors affecting contamination of raw milk.

    PubMed

    Magnusson, M; Christiansson, A; Svensson, B

    2007-06-01

    The contamination of raw milk with Bacillus cereus spores was studied during the indoor confinement of dairy cattle. The occurrence of spores in fresh and used bedding material, air samples, feed, feces, and the rinse water from milking equipment was compared with the spore level in bulk tank milk on 2 farms, one of which had 2 different housing systems. A less extensive study was carried out on an additional 5 farms. High spore concentrations of >100 spores/L in the raw milk were found on 4 of the farms. The number of spores found in the feed, feces, and air was too small to be of importance for milk contamination. Elevated spore contents in the rinse water from the milking equipment (up to 322 spores/L) were observed and large numbers of spores were found in the used bedding material, especially in free stalls with >5 cm deep sawdust beds. At most, 87,000 spores/g were found in used sawdust bedding. A positive correlation was found between the spore content in used bedding material and milk (r = 0.72). Comparison of the genetic fingerprints obtained by the random amplified polymorphic DNA PCR of isolates of B. cereus from the different sources indicated that used bedding material was the major source of contamination. A separate feeding experiment in which cows were experimentally fed B. cereus spores showed a positive relationship between the number of spores in the feed and feces and in the feces and milk (r = 0.78). The results showed that contaminated feed could be a significant source of spore contamination of raw milk if the number of spores excreted in the feces exceeded 100,000/g. PMID:17517714

  18. Factors influencing internal color of cooked meats.

    PubMed

    Suman, Surendranath P; Nair, Mahesh N; Joseph, Poulson; Hunt, Melvin C

    2016-10-01

    This manuscript overviews the pertinent research on internal color of uncured cooked meats, biochemical processes involved in meat cookery, and fundamental mechanisms governing myoglobin thermal stability. Heat-induced denaturation of myoglobin, responsible for the characteristic dull-brown color of cooked meats, is influenced by a multitude of endogenous (i.e., pH, muscle source, species, redox state) and exogenous (i.e., packaging, ingredients, storage) factors. The interactions between these factors critically influence the internal cooked color and can confuse the consumers, who often perceive cooked color to be a reliable indicator for doneness and safety. While certain phenomena in cooked meat color are cosmetic in nature, others can mislead consumers and result in foodborne illnesses. Research in meat color suggests that processing technologies and cooking practices in industry as well as households influence the internal cooked color. Additionally, the guidelines of many international public health and regulatory authorities recommend using meat thermometers to determine safe cooking endpoint temperature and to ensure product safety. PMID:27131513

  19. Prevalence and risk factors for Coxiella burnetii (Q fever) in Dutch dairy cattle herds based on bulk tank milk testing.

    PubMed

    van Engelen, E; Schotten, N; Schimmer, B; Hautvast, J L A; van Schaik, G; van Duijnhoven, Y T H P

    2014-11-01

    Despite cattle herds can harbor Coxiella burnetii, risk factors for C. burnetii presence in dairy cattle herds are largely unknown. Therefore, C. burnetii herd prevalence and risk factors for bulk tank milk (BTM) positivity were investigated. In this cross-sectional study, a questionnaire was filled out by the farmer and BTM from 301 farms was tested by ELISA for presence of C. burnetii antibodies and PCR for presence of C. burnetii DNA. Risk factors were identified by univariable and multivariable logistic regression analyses. Antibodies to C. burnetii were detected in 81.6% (CI: 77.2-85.9) and C. burnetii DNA in 18.8% (CI: 14.4-23.1) of the BTM samples. Herd size (OR=1.1 per 10 cows), cleaning the bedding of the cubicles at most every other day (OR=2.8) and purchase of cattle from at least two addresses (OR=3.1) showed a significant and positive association with ELISA positivity and use of an automatic milking system a negative association (OR=0.3). Risk factors for PCR positivity were purchase of cattle from at least two delivery addresses (OR=3.2), presence of cows with ticks (OR=2.0), use of an automatic milking system (OR=0.2) and presence of goats or sheep on the farm (OR=0.4). Biosecurity and general hygiene seem associated with introduction and spread of C. burnetii in dairy herds. PMID:25239684

  20. Risk factors for Coxiella burnetii antibodies in bulk tank milk from Danish dairy herds.

    PubMed

    Agger, Jens Frederik; Paul, Suman; Christoffersen, Anna-Bodil; Agerholm, Jørgen Steen

    2013-01-01

    The aim was to identify risk factors associated with Coxiella burnetii antibody positivity in bulk tank milk (BTM) samples from 100 randomly selected Danish dairy cattle herds. Antibody levels were measured by an enzyme-linked immuno-sorbent assay. Before testing the herds, the farm managers were interviewed about hired labour, biosecurity, housing and herd health during the 12 months prior to the study. Variables considered important for C. burnetii antibody positivity in multivariable logistic regression analysis included the sharing of machines between farms (OR = 3.6), human contacts (OR = 4.2), artificial insemination by other people than artificial insemination technicians (OR = 7.7), routine herd health contract with the veterinarian (OR = 4.3) and hygiene precautions taken by veterinarians (OR = 5). In addition, herd size, hired labour, trading of cattle between farms, quarantine and use of calving and disease pens also showed significant association in univariable analysis. This study demonstrates that strict biosecurity is important for the prevention of infections with C. burnetii. PMID:24228845

  1. Phagocytosis mechanism of apoptotic granulosa cells regulated by milk-fat globule-EGF factor 8.

    PubMed

    Naka, Mayumi; Kusakabe, Ken; Takeshita, Ai; Nakagawa, Hiroshi; Ito, Yuko; Shibata, Masa-Aki; Otsuki, Yoshinori

    2009-09-01

    In the process of ovary sexual maturation, most immature ovarian follicles degrade into atretic follicles accompanied by apoptosis in granulosa cells. Macrophages can recognize apoptotic cells through specific binding with phosphatidylserine (PS), exposed on the surface of apoptotic cells, which is mediated by milk-fat globule-EGF factor 8 (MFG-E8). In the present research, we examined the involvement of the MFG-E8-dependent phagocytosis system in the atretic follicles of developing mouse ovaries. The number of atretic follicles and DNA-fragmented granulosa cells significantly increased in B6C3F1 mice during 2 to 6 weeks. Chromatin-condensed granulosa cells were engulfed by macrophages, which existed in the stroma or atretic follicles, or by neighboring normal granulosa cells. MFG-E8 mRNA increased in ovaries during 2 to 6 weeks, and immunoreactivity of MFG-E8 was detected at the surface of apoptotic cells existing around the antrum. Immunoelectron microscopic study revealed MFG-E8-positive signals on the membrane of apoptotic cells near macrophages, but apoptotic cells engulfed by neighboring granulosa cells showed few signals. Anti-Fas antibody elevated the annexin-V-positive reaction in isolated granulosa cells from 3-week-old mouse ovaries. MFG-E8 seems to act on the phagocytosis of apoptotic granulosa cells via macrophages and contribute to the regression process of atretic follicles. PMID:19784740

  2. Influence of stage of lactation on the triacylglycerol composition of buffalo milk fat.

    PubMed

    Arumughan, C; Narayanan, K M

    1981-03-01

    Milk fats obtained from colostrum and early, middle and late lactation samples of buffalo milk were analyzed for their triacylglycerol (TG) compositions. Each milk fat was first separated by thin layer chromatography (TLC) into high, medium and low molecular weight TG. The TG fractions thus obtained were further segregated by argentation TLC, according to their degree of unsaturation into saturated, trans-monoene, cis-monoene, diene and polyene species. With progressive lactation, the major changes from colostral fat were an increase in lower fatty acids and decline in oleic acid. This caused, in turn, marked variations in saturated TG and diene TG and, to a smaller extent, in polyene TG. Monoene TG, both cis and trans, remained practically constant throughout. These trends were largely reversed toward the end of lactation. PMID:7219086

  3. A review of nutritional and physiological factors affecting goat milk lipid synthesis and lipolysis.

    PubMed

    Chilliard, Y; Ferlay, A; Rouel, J; Lamberet, G

    2003-05-01

    Although the effect of lactation stage is similar, the responses of milk yield and composition (fat and protein contents) to different types of lipid supplements differ greatly between goats and cows. Milk fat content increases with almost all studied fat supplements in goats but not in cows. However, the response of milk fatty acid (FA) composition is similar, at least for major FA, including conjugated linoleic acid (CLA) in goats and cows supplemented with either protected or unprotected lipid supplements. Goat milk CLA content increases sharply after either vegetable oil supplementation or fresh grass feeding, but does not change markedly when goats receive whole untreated oilseeds. Important interactions are observed between the nature of forages and of oil supplements on trans-10 and trans-11 C18:1 and CLA. Peculiarities of goat milk FA composition and lipolytic system play an important role in the development of either goat flavor (release of branched, medium-chain FA) or rancidity (excessive release of butyric acid). The lipoprotein lipase (LPL) activity, although lower in goat than in cow milk, is more bound to the fat globules and better correlated to spontaneous lipolysis in goat milk. The regulation of spontaneous lipolysis differs widely between goats and cows. Goat milk lipolysis and LPL activity vary considerably and in parallel across goat breeds or genotypes, and are low during early and late lactation, as well as when animals are underfed or receive a diet supplemented with protected or unprotected vegetable oils. This could contribute to decreases in the specific flavor of goat dairy products with diets rich in fat. PMID:12778586

  4. Factors influencing variation in dentist service rates.

    PubMed

    Grembowski, D; Milgrom, P; Fiset, L

    1990-01-01

    In the previous article, we calculated dentist service rates for 200 general dentists based on a homogeneous, well-educated, upper-middle-class population of patients. Wide variations in the rates were detected. In this analysis, factors influencing variation in the rates were identified. Variation in rates for categories of dental services was explained by practice characteristics, patient exposure to fluoridated water supplies, and non-price competition in the dental market. Rates were greatest in large, busy practices in markets with high fees. Older practices consistently had lower rates across services. As a whole, these variables explained between 5 and 30 percent of the variation in the rates. PMID:2118182

  5. Factors influencing aircraft ground handling performance

    NASA Technical Reports Server (NTRS)

    Yager, T. J.

    1983-01-01

    Problems associated with aircraft ground handling operations on wet runways are discussed and major factors which influence tire/runway braking and cornering traction capability are identified including runway characteristics, tire hydroplaning, brake system anomalies, and pilot inputs. Research results from tests with instrumented ground vehicles and aircraft, and aircraft wet runway accident investigation are summarized to indicate the effects of different aircraft, tire, and runway parameters. Several promising means are described for improving tire/runway water drainage capability, brake system efficiency, and pilot training to help optimize aircraft traction performance on wet runways.

  6. [Influence of weather factors on suicidal hangings].

    PubMed

    Trepińska, Janina; Piotrowicz, Katarzyna; Bakowski, Rafał; Bolechała, Filip; Trela, Franciszek

    2005-01-01

    The paper presents a certain biometeorological problem. The evaluation of influence of weather factors on frequency of suicidal cases by hanging in the area of Cracow City during 1991-2002 was examined. Rapid changes of air pressure, air temperature, hot, sweltering and sultry days, very frosty days, days with strong or foehn wind, days with thunderstorms, fog and haze were selected as unfavourable weather factors. They give an occasion for strong psychical stress. The results of detailed investigations are next: more frequency of cases of suicide during the advance of cold fronts, rapid decreases of air pressure during hot, sweltering and sultry days, days with thunderstorms and foehn winds in the Tatra Mountains. PMID:16521499

  7. Factors influencing global antiretroviral procurement prices

    PubMed Central

    2009-01-01

    Background Antiretroviral medicines (ARVs) are one of the most costly parts of HIV/AIDS treatment. Many countries are struggling to provide universal access to ARVs for all people living with HIV and AIDS. Although substantial price reductions of ARVs have occurred, especially between 2002 and 2008, achieving sustainable access for the next several decades remains a major challenge for most low- and middle-income countries. The objectives of the present study were twofold: first, to analyze global ARV prices between 2005 and 2008 and associated factors, particularly procurement methods and key donor policies on ARV procurement efficiency; second, to discuss the options of procurement processes and policies that should be considered when implementing or reforming access to ARV programs. Methods An ARV-medicines price-analysis was carried out using the Global Price Reporting Mechanism from the World Health Organization. For a selection of 12 ARVs, global median prices and price variation were calculated. Linear regression models for each ARV were used to identify factors that were associated with lower procurement prices. Logistic regression models were used to identify the characteristics of those countries which procure below the highest and lowest direct manufactured costs. Results Three key factors appear to have an influence on a country's ARV prices: (a) whether the product is generic or not; (b) the socioeconomic status of the country; (c) whether the country is a member of the Clinton HIV/AIDS Initiative. Factors which did not influence procurement below the highest direct manufactured costs were HIV prevalence, procurement volume, whether the country belongs to the least developed countries or a focus country of the United States President's Emergency Plan For AIDS Relief. Conclusion One of the principal mechanisms that can help to lower prices for ARV over the next several decades is increasing procurement efficiency. Benchmarking prices could be one useful

  8. Factors influencing breast changes after pregnancy.

    PubMed

    Rauh, Claudia; Faschingbauer, Florian; Haeberle, Lothar; Jud, Sebastian M; Heusinger, Katharina; Fasching, Peter A; Goecke, Tamme W; Rajakaruna, Nadeeka; Voigt, Franziska; Bani, Mayada R; Lux, Michael P; Renner, Stefan P; Loehberg, Christian R; Hartmann, Arndt; Schulz-Wendtland, Ruediger; Beckmann, Matthias W; Bayer, Christian M

    2013-05-01

    Pregnancy and breastfeeding are major factors reducing breast cancer (BC) risk. A potential mechanism for this effect might be changes in mammographic density, but other factors might be involved. The aim of this study was to investigate factors influencing changes in breast size and breast stiffness after pregnancy. Of a consecutive cohort of 5991 women who gave birth between 1996 and 1999, 559 replied to a questionnaire including questions about breast changes. The women completed their own assessments of changes in breast size and stiffness since their last pregnancy. Factors being investigated regarding their predictive value for these changes were: BMI before pregnancy, weight gain, age at first full-term pregnancy (FFTP), number of pregnancies, breastfeeding, and BMI of the children's fathers. A decrease in breast size was reported in 21.8% of the participants and an increase in 35.1%. With regard to the breast stiffness, 66.4% reported a decrease and only 5% reported an increase. Independent predictors for increased breast size were age at FFTP, increase in BMI since last pregnancy, BMI before pregnancy, and time since FFTP. Factors predictive of greater breast stiffness included age at FFTP, BMI before FFTP, time since FFTP, breastfeeding status, and number of pregnancies. Breast changes after pregnancy depend on several variables, which are described as BC-risk factors. Individual reaction of the female breast to a pregnancy leads to different outcomes with regard to breast size and stiffness. Further studies are needed to clarify whether these individual responses interact with the effect of pregnancy on the BC risk. PMID:23022745

  9. Adoption of milk cooling technology among smallholder dairy farmers in Kenya.

    PubMed

    Gachango, Florence Gathoni; Andersen, Laura Mørch; Pedersen, Søren Marcus

    2014-01-01

    Factors influencing adoption of milk cooling technology were studied with data for 90 smallholder dairy farmers who were randomly selected from seven dairy cooperative societies in Kiambu County, Kenya. Logistic regression identified the age of the household head, daily household milk consumption, freehold land ownership, fodder production area, number of female calves, cooperative membership and cooperative services as significant factors influencing farmers' willingness to invest in milk cooling technology. These findings offer an entry point for increased interventions by policy makers and various dairy sector stakeholders in promoting milk cooling technology with the aim of significantly reducing post-harvest losses and increasing the sector's competitiveness. PMID:24048823

  10. Factors that influence engagement in collaborative practice

    PubMed Central

    Herbert, Carol P.; Bainbridge, Lesley; Bickford, Julia; Baptiste, Susan; Brajtman, Susan; Dryden, Trish; Hall, Pippa; Risdon, Cathy; Solomon, Patricia

    2007-01-01

    OBJECTIVE To generate hypotheses regarding factors that might influence engagement in collaborative practice. DESIGN Qualitative study using in-depth interviews. SETTING Participants interviewed each other in dyads. The pairing was based upon geographical location and proximity to each other. PARTICIPANTS Eight professionals from the disciplines of medicine, nursing, occupational therapy, physical therapy, and massage therapy. METHOD Semistructured interviews, lasting 30 to 45 minutes each, were recorded and transcribed verbatim. The transcripts were read by all research team members using independent content analysis for common words, phrases, statements, or units of text for key themes. At a subsequent face-to-face meeting, the team used an iterative process of comparing and contrasting key themes until consensus was reached. The transcripts were then analyzed further for subthemes using NVivo software. MAIN FINDINGS Initial findings suggest that some common characteristics grounded in family history, school experiences, social interactions, and professional training might influence collaborative practice choices. The narrative form of the interview broke down interpersonal and interprofessional barriers, creating a new level of trust and respect that could improve professional collaboration. CONCLUSION This study suggests that life experiences from childhood into later adulthood can and do influence professional choices. PMID:17872847

  11. Real-time evaluation of milk quality as reflected by clotting parameters of individual cow's milk during the milking session, between day-to-day and during lactation.

    PubMed

    Leitner, Gabriel; Merin, Uzi; Jacoby, Shamay; Bezman, Dror; Lemberskiy-Kuzin, Liubov; Katz, Gil

    2013-09-01

    together with high milk yield >50 l/day, and late in lactation together with low milk yield<15 l/day and estrous (0 to 5 days) were also important influencing factors for low-quality milk. However, ∼50% of the tested variables did not explain any of the factors responsible for the cow producing milk in the low - 10% Afi-CF. PMID:23537499

  12. Effects of milk powders in milk chocolate.

    PubMed

    Liang, B; Hartel, R W

    2004-01-01

    The physical characteristics of milk powders used in chocolate can have significant impact on the processing conditions needed to make that chocolate and the physical and organoleptic properties of the finished product. Four milk powders with different particle characteristics (size, shape, density) and "free" milk fat levels (easily extracted with organic solvent) were evaluated for their effect on the processing conditions and characteristics of chocolates in which they were used. Many aspects of chocolate manufacture and storage (tempering conditions, melt rheology, hardness, bloom stability) were dependent on the level of free milk fat in the milk powder. However, particle characteristics of the milk powder also influenced the physical and sensory properties of the final products. PMID:14765806

  13. Psychosocial Factors Influencing Calcium Intake and Bone Quality in Middle-School Girls

    PubMed Central

    Hoelscher, Deanna M.; Kelder, Steven H.; Diamond, Pamela; Day, R. Sue; Hergenroeder, Albert

    2015-01-01

    Calcium intake has been associated with promoting bone health in children and adolescents, thus, preventing osteoporosis later in life. Behavior change such as increased calcium intake, as well as physiological factors such as bone quality, may be facilitated by psychosocial and environmental factors. The purpose of this study was to identify pathways by which psychosocial factors influence calcium intake and bone quality in middle-school girls. The study design was cross-sectional. Baseline data from the Incorporating More Physical Activity and Calcium in Teens (IMPACT) study, collected in 2001–2003, were utilized. IMPACT, was a 1 ½ years nutrition and physical activity intervention study, designed to improve bone density in 717 middle-school girls in Texas. Main outcome measures were: 1) calcium intake determined using mean milligrams of calcium consumed per day and number of glasses of milk consumed per day, and 2) bone quality determined using calcaneal stiffness index. Confirmatory factor analysis and path analysis were performed to identify the direct and indirect pathways used by various psychosocial factors such as knowledge, self-efficacy, outcome expectations and milk availability at home, to influence calcium intake and bone quality. Results showed that knowledge of osteoporosis and calcium rich foods had an indirect effect on calcium intake, with outcome expectations as the mediating variable (β=0.035 and β=0.03 respectively, p < 0.05). Calcium self-efficacy had a significant indirect effect on calcium intake, with outcome expectations as the mediator (β=0.085, p < 0.05). None of the variables significantly influenced bone quality. Thus, several direct and indirect pathways used to influence calcium intake among adolescent girls, were identified. These findings are critical for the development of effective interventions to promote calcium intake in this population. PMID:20497785

  14. Factors influencing BMI classifications of Korean adults

    PubMed Central

    Chang, Ae Kyung; Choi, Jin Yi

    2015-01-01

    [Purpose] This study aimed to identify factors influencing the BMI classifications of 3,583 Korean adults using data from the fifth Korean National Health and Nutrition Examination Survey. [Subjects and Methods] Measures included lifestyle factors, physiologic factors, perceived health state, stress, subjective body recognition, health-related quality of life, and weight control behavior. [Results] Body perception scores were lower with underweight and higher with overweight and obesity than with a healthy weight. There was a lower proportion of underweight men and a higher proportion of overweight or obese men than women. Instances of Alcohol Use Identification Scores (AUDIT) ≥ 9 were proportionately lower with underweight and more with overweight or obesity relative to an AUDIT score < 9 with healthy weight. Hemoglobin A1c and systolic blood pressure were higher with obesity than with healthy weight. The total cholesterol level was greater with overweight and obesity than with healthy weight. [Conclusion] These results suggest that obesity intervention for adults should be based on age and sex and should include drinking habits and physical activity. PMID:26157264

  15. Molecular descriptors that influence the amount of drugs transfer into human breast milk.

    PubMed

    Agatonovic-Kustrin, S; Ling, L H; Tham, S Y; Alany, R G

    2002-06-20

    Most drugs are excreted into breast milk to some extent and are bioavailable to the infant. The ability to predict the approximate amount of drug that might be present in milk from the drug structure would be very useful in the clinical setting. The aim of this research was to simplify and upgrade the previously developed model for prediction of the milk to plasma (M/P) concentration ratio, given only the molecular structure of the drug. The set of 123 drug compounds, with experimentally derived M/P values taken from the literature, was used to develop, test and validate a predictive model. Each compound was encoded with 71 calculated molecular structure descriptors, including constitutional descriptors, topological descriptors, molecular connectivity, geometrical descriptors, quantum chemical descriptors, physicochemical descriptors and liquid properties. Genetic algorithm was used to select a subset of the descriptors that best describe the drug transfer into breast milk and artificial neural network (ANN) to correlate selected descriptors with the M/P ratio and develop a QSAR. The averaged literature M/P values were used as the ANN's output and calculated molecular descriptors as the inputs. A nine-descriptor nonlinear computational neural network model has been developed for the estimation of M/P ratio values for a data set of 123 drugs. The model included the percent of oxygen, parachor, density, highest occupied molecular orbital energy (HOMO), topological indices (chiV2, chi2 and chi1) and shape indices (kappa3, kappa2), as the inputs had four hidden neurons and one output neuron. The QSPR that was developed indicates that molecular size (parachor, density) shape (topological shape indices, molecular connectivity indices) and electronic properties (HOMO) are the most important for drug transfer into breast milk. Unlike previously reported models, the QSPR model described here does not require experimentally derived parameters and could potentially provide a

  16. Factors affecting the calcium, magnesium and phosphorus content of beef cow milk.

    PubMed

    Hidiroglou, M; Proulx, J G

    1982-04-01

    This paper reports the calcium, magnesium and phosphorus content of milk from Shorthorn cattle during the five month calf nursing period as well as the effect of prepartum administration of a single intramuscular dose of vitamin D3 or of 25-hydroxyvitamin D3 on the milk mineral constituents. The colostrum of the group which received 25-hydroxyvitamin D3 was found to contain a higher percentage of calcium on the second and third day than the colostrum of control cows or those receiving D3. No differences occurred in colostrum magnesium or phosphorus contents due to prepartum treatment. Calcium, magnesium and phosphorus concentrations were all high in the first day of lactation, but declined until the third day after parturition. Milk calcium, magnesium and phosphorus content of individual cows was not uniform throughout the lactation and the variation was different for different cows. PMID:7093815

  17. Factors influencing the uptake of orthodontic treatment.

    PubMed

    O'Brien, K; McComb, J L; Fox, N; Wright, J

    1996-11-01

    The aim of this investigation was to evaluate the factors that influenced the uptake of orthodontic treatment for patients who were referred for orthodontic treatment to two types of orthodontic treatment provider; a fee per item and hospital service. The following data were collected: (i) basic demographic data; (ii) the need for orthodontic treatment as measured by IOTN; and (iii) the outcome of the consultation. The data analysis with logistic regression revealed that the following variables had a predictive effect on the uptake of treatment: (i) the need for orthodontic treatment; and (ii) the patient's gender. Most of the patients that were referred and accepted for treatment had a definite need for orthodontic treatment. PMID:8985570

  18. Factors influencing human leukocyte adherence in vitro.

    PubMed

    Stepniewicz, W; Tchórzewski, H; Luciak, M

    1983-01-01

    Studies were performed on factors influencing leucocyte adherence in vitro. Blood condensation was found to increase leukocyte adherence. Addition of heparin, dextran or ethanol caused a significant reduction of white blood cell count in blood samples in comparison with blood mixed with sodium EDTA or ACD solution. This suggests the existence of two granulocyte subpopulations; viz, rapidly adhering and slowly adhering. Heparin enhanced granulocyte adherence, while dextran and ethanol decreased it. Five-day storage of ACD blood led to a decrease in granulocyte adherence, while addition of heparin or histamine to ACD blood prevented this change to occur. The glucose concentration of 1,000 mg/dl augmented granulocyte adherence, while higher glucose concentrations induced its progressive fall below the control values. There was no significant change of lymphocyte adherence during the experiments. PMID:6194070

  19. Factors influencing consumer dietary health preventative behaviours

    PubMed Central

    Petrovici, Dan A; Ritson, Christopher

    2006-01-01

    Background The deterioration of the health status of the Romanian population during the economic transition from a centrally planned to a free market economy has been linked to lifestyles factors (e.g. diet) regarded as a main determinants of the disparity in life expectancy between Eastern and Western Europe. Reforms in the health care system in this transition economy aim to focus on preventive action. The purpose of this study was to identify the factors that impact on the individual decision to engage in Dietary Health Preventive Behaviour (DHPB) and investigate their influence in the context of an adapted health cognition model. Methods A population-based study recruited 485 adult respondents using random route sampling and face-to-face administered questionnaires. Results and discussion Respondents' health motivation, beliefs that diet can prevent disease, knowledge about nutrition, level of education attainment and age have a positive influence on DHPB. Perceived barriers to healthy eating have a negative impact on alcohol moderation. The information acquisition behaviour (frequency of reading food labels) is negatively predicted by age and positively predicted by health motivation, education, self-reported knowledge about nutrition and household financial status. A significant segment of respondents believe they are not susceptible to the elicited diseases. Health promotion strategies should aim to change the judgments of health risk. Conclusion The adaptation of the Health Belief Model and the Theory of Health Preventive Behaviour represents a valid framework of predicting DHPB. The negative sign of perceived threat of disease on DHPB may suggest that, under an income constraint, consumers tend to trade off long-term health benefits for short-term benefits. This cautions against the use of negative messages in public health campaigns. Raising the awareness of diet-disease relationships, knowledge about nutrition (particularly sources and risks associated

  20. Effect of dam factors on milk intake and performance of Belgian Blue suckling calves.

    PubMed

    Fiems, L O; Van Caelenbergh, W; De Campeneere, S; De Brabander, D L

    2008-01-01

    Milk intake data were collected at 4-week intervals from Belgian Blue double-muscled (BBDM) suckling calves up to 16 weeks after birth. Dams were fed at 100%, 90%, 80% or 70% of their energy requirements during a 140-day indoor period from the beginning of December to the end of April (restriction period). Afterwards, cows were turned out on pasture (re-alimentation period). Mean calving date was 3 June, but parturitions were spread over the year. A total of 521 individual milk intake (IMI) and 120 average daily milk intake (AMI, mean of IMI) records were collected. IMI amounted to 7.0 ± 2.2 kg/day and was not affected by energy level during the indoor period. It was highest in May and June. Calves born out of multiparous cows consumed more milk than those born out of primiparous cows (7.4 v. 6.2 kg per day; P = 0.001), while intake tended to be higher in female than in male calves (7.2 v. 6.8 kg per day; P = 0.044). Dam age at calving, parity, post partum weight and body condition were only weakly correlated with AMI (r 0.4). AMI was correlated with pre-weaning live-weight gain (r = 0.807) and weaning weight (r = 0.783), with a slightly higher correlation for male than for female calves. Daily live-weight gain during the suckling period was increased by 79 g per extra kg daily milk intake on average, and by 86 and 74 g, respectively, for male and female calves. Calf solid feed intake was low, even when milk intake was low. In terms of net energy intake, milk was only substituted for solid feed by 29%. It can be concluded from the calf intake that milk production in BBDM cows is comparable with that of cows from other beef breeds, but its variation is considerable, complicating an accurate estimation. PMID:22444972

  1. Influencing Factors of Thermogenic Adipose Tissue Activity

    PubMed Central

    Zhang, Guoqing; Sun, Qinghua; Liu, Cuiqing

    2016-01-01

    Obesity is an escalating public health challenge and contributes tremendously to the disease burden globally. New therapeutic strategies are required to alleviate the health impact of obesity-related metabolic dysfunction. Brown adipose tissue (BAT) is specialized for dissipating chemical energy for thermogenesis as a defense against cold environment. Intriguingly, the brown-fat like adipocytes that dispersed throughout white adipose tissue (WAT) in rodents and humans, called “brite” or “beige” adipocytes, share similar thermogenic characteristics to brown adipocytes. Recently, researchers have focused on cognition of these thermogenic adipose tissues. Some factors have been identified to regulate the development and function of thermogenic adipose tissues. Cold exposure, pharmacological conditions, and lifestyle can enhance non-shivering thermogenesis and metabolism via some mechanisms. However, environmental pollutants, such as ambient fine particulates and ozone, may impair the function of these thermogenic adipose tissues and thereby induce metabolic dysfunction. In this review, the origin, function and influencing factors of thermogenic adipose tissues were summarized and it will provide insights into identifying new therapeutic strategies for the treatment of obesity and obesity-related diseases. PMID:26903879

  2. Influencing Factors of Thermogenic Adipose Tissue Activity.

    PubMed

    Zhang, Guoqing; Sun, Qinghua; Liu, Cuiqing

    2016-01-01

    Obesity is an escalating public health challenge and contributes tremendously to the disease burden globally. New therapeutic strategies are required to alleviate the health impact of obesity-related metabolic dysfunction. Brown adipose tissue (BAT) is specialized for dissipating chemical energy for thermogenesis as a defense against cold environment. Intriguingly, the brown-fat like adipocytes that dispersed throughout white adipose tissue (WAT) in rodents and humans, called "brite" or "beige" adipocytes, share similar thermogenic characteristics to brown adipocytes. Recently, researchers have focused on cognition of these thermogenic adipose tissues. Some factors have been identified to regulate the development and function of thermogenic adipose tissues. Cold exposure, pharmacological conditions, and lifestyle can enhance non-shivering thermogenesis and metabolism via some mechanisms. However, environmental pollutants, such as ambient fine particulates and ozone, may impair the function of these thermogenic adipose tissues and thereby induce metabolic dysfunction. In this review, the origin, function and influencing factors of thermogenic adipose tissues were summarized and it will provide insights into identifying new therapeutic strategies for the treatment of obesity and obesity-related diseases. PMID:26903879

  3. Factors Influencing Early Dental Implant Failures.

    PubMed

    Chrcanovic, B R; Kisch, J; Albrektsson, T; Wennerberg, A

    2016-08-01

    The purpose of the present study was to assess the influence of local and systemic factors on the occurrence of dental implant failures up to the second-stage surgery (abutment connection). This retrospective study is based on 2,670 patients who received 10,096 implants and were consecutively treated with implant-supported prostheses between 1980 and 2014 at 1 specialist clinic. Several anatomic-, patient-, health-, and implant-related factors were collected. Descriptive statistics were used to describe the patients and implants. Univariate and multivariate logistic regression models were used at the patient level as well as the implant level to evaluate the effect of explanatory variables on the failure of implants up to abutment connection. A generalized estimating equation method was used for the implant-level analysis to account for the fact that repeated observations (several implants) were available for a single patient. Overall, 642 implants (6.36%) failed, of which 176 (1.74%) in 139 patients were lost up to second-stage surgery. The distribution of implants in sites of different bone quantities and qualities was quite similar between implants lost up to and after abutment connection. Smoking and the intake of antidepressants were the statistically significant predictors in the multivariate model (ClinicalTrials.gov NCT02369562). PMID:27146701

  4. Factors Influencing Biogenic Amines Accumulation in Dairy Products

    PubMed Central

    Linares, Daniel M.; del Río, Beatriz; Ladero, Victor; Martínez, Noelia; Fernández, María; Martín, María Cruz; Álvarez, Miguel A.

    2012-01-01

    Fermented foods are among the food products more often complained of having caused episodes of biogenic amines (BA) poisoning. Concerning milk-based fermented foods, cheese is the main product likely to contain potentially harmful levels of BA, specially tyramine, histamine, and putrescine. Prompted by the increasing awareness of the risks related to dietary uptake of high biogenic amine loads, in this review we report all those elaboration and processing technological aspects affecting BA biosynthesis and accumulation in dairy foods. Improved knowledge of the factors involved in the synthesis and accumulation of BA should lead to a reduction in their incidence in milk products. Synthesis of BA is possible only when three conditions converge: (i) availability of the substrate amino acids; (ii) presence of microorganisms with the appropriate catabolic pathway activated; and (iii) environmental conditions favorable to the decarboxylation activity. These conditions depend on several factors such as milk treatment (pasteurization), use of starter cultures, NaCl concentration, time, and temperature of ripening and preservation, pH, temperature, or post-ripening technological processes, which will be discussed in this chapter. PMID:22783233

  5. Thermal and structural behavior of milk fat. 3. Influence of cooling rate and droplet size on cream crystallization.

    PubMed

    Lopez, Christelle; Bourgaux, Claudie; Lesieur, Pierre; Bernadou, Sophie; Keller, Gérard; Ollivon, Michel

    2002-10-01

    , demonstrating the usefulness of the small-angle XRD technique. Reconstituted emulsions homogenized under different pressures are used to determine the influence of droplet size on crystallization. The decrease of droplet size induces (i) a higher supercooling/supersaturation and (ii) a higher disorder and/or a smaller size of TG crystals within the emulsion droplets. At the supramolecular scale, polarized light microscopy shows that various cooling rates applied in situ using a temperature-controlled stage directly influence crystal sizes and their type of organization within milk fat globules. The faster the cooling rate, the smaller the size of the crystals within the globules. PMID:12702426

  6. Storage of milk powders under adverse conditions. 2. Influence on the content of water-soluble vitamins.

    PubMed

    Ford, J E; Hurrell, R F; Finot, P A

    1983-05-01

    g water/kg, storage at 37 degrees in O2 and N2 gave much the same results as for the corresponding whole-milk powder. The presence of milk fat had no marked effect on the stability of the water-soluble vitamins. Destruction of vitamins was clearly linked to the progress of Maillard-type reactions and was strongly influenced by time and temperature of storage, moisture content and, in some instances, by the presence of O2. PMID:6407521

  7. Milk digesta and milk protein fractions influence the adherence of Lactobacillus gasseri R and Lactobacillus casei FMP to human cultured cells.

    PubMed

    Volstatova, Tereza; Havlik, Jaroslav; Potuckova, Miroslava; Geigerova, Martina

    2016-08-10

    Adhesion to the intestinal epithelium is considered an important feature of probiotic bacteria, which may increase their persistence in the intestine, allowing them to exert their beneficial health effect or promote the colonisation process. However, this feature might be largely dependent on the host specificity or diet. In the present study, we investigated the effect of selected milks and milk protein fractions on the ability of selected lactobacilli to adhere to the cells of an intestinal model based on co-culture Caco-2/HT29-MTX cell lines. Most milk digesta did not significantly affect bacterial adhesion except for UHT-treated milk and sheep milk. The presence of UHT-treated milk digesta reduced the adhesion of Lactobacillus gasseri R by 61% but not that of Lactobacillus casei FMP. However, sheep milk significantly increased the adherence of L. casei FMP (P < 0.05) but not of L. gasseri R. Among the protein fractions, rennet casein (RCN) and bovine serum albumin (BSA) showed reproducible patterns and strain-specific effects on bacterial adherence. While RCN reduced the adherence of L. gasseri R to <50% compared to the control, it did not have a significant effect on L. casei FMP. In contrast, BSA reduced L. casei FMP adherence to a higher extent than that of L. gasseri R. Whey protein (WH) tended to increase the adherence of both strains by 130%-180%. Recently, interactions between the host diet and its microbiota have attracted considerable interest. Our results may explain one of the aspects of the role of milk in the development of microbiota or support of probiotic supplements. Based on our data, we conclude that the persistence of probiotic strains supplemented as part of dairy food or constitutional microbiota in the gut might be affected negatively or positively by the food matrix through complex strain or concentration dependent effects. PMID:27435508

  8. Chemical contaminants in breast milk: time trends and regional variability.

    PubMed Central

    Solomon, Gina M; Weiss, Pilar M

    2002-01-01

    Research on environmentally related chemical contaminants in breast milk spans several decades and dozens of countries. The ability to use this research as an environmental indicator is limited because of a lack of consistent protocols. Data on xenobiotics in breast milk are influenced by choices in sample selection, sample pooling, analysis, and reporting. In addition, most studies have focused only on a small panel of persistent organic pollutants, despite indications that a wide range of additional chemical contaminants may also enter breast milk. Despite these limitations, however, it is possible to draw some generalizations. In this paper we review available data on levels of organochlorine pesticides, polychlorinated biphenyls (PCBs), polychlorinated dibenzodioxins (PCDDs), polybrominated diphenyl ethers (PBDEs), metals, and solvents in breast milk. Examples drawn from around the world illustrate the available data and the patterns that have appeared in various areas over time. Over the past few decades, levels of the organochlorine pesticides, PCBs, and dioxins have declined in breast milk in countries where these chemicals have been banned or otherwise regulated. In contrast, the levels of PBDEs are rising. Regional differences in levels of xenobiotics in breast milk are related to historical and current local use patterns. Diet is a major factor that influences breast milk levels of persistent organic pollutants, with patterns in fish consumption playing a particularly significant role. Improved global breast milk monitoring programs would allow for more consistent data on trends over time, detection of new xenobiotics in breast milk, and identification of disproportionately exposed populations. PMID:12055065

  9. Human Milk Cortisol is Associated With Infant Temperament

    PubMed Central

    Grey, Katherine R.; Davis, Elysia Poggi; Sandman, Curt A.; Glynn, Laura M.

    2012-01-01

    The implications of the biologically active elements in milk for the mammalian infant are largely unknown. Animal models demonstrate that transmission of glucocorticoids through milk influences behavior and modifies brain development in offspring. The aim of this study was to determine the relation between human milk cortisol levels and temperament of the breastfed infant. Fifty-two mother and infant pairs participated when the infants were three-months old. Milk cortisol levels were assessed and each mother completed the Infant Behavior Questionnaire (IBQ), a widely used parent-report measure of infant temperament. Analyses revealed a positive association between milk cortisol and the Negative Affectivity dimension of the IBQ (partial r =.37, p < .01). No correlation was found between elevated cortisol levels and the Surgency/Extraversion or the Orienting/Regulation dimensions. Further, the positive association between increased maternal milk cortisol and Negative Affectivity was present among girls (β = .59, p < .01), but not among boys. (Although, the sex by milk cortisol interaction term was not statistically significant, suggesting that these results require replication.) Environmental factors such as maternal demographics and negative maternal affect (depression and perceived stress) at the time of assessment did not account for the positive association. The findings support the proposal that exposure to elevated levels of cortisol in human milk influences infant temperament. The findings further suggest that mothers have the ability shape offspring phenotype through the transmission of biologically active components in milk. PMID:23265309

  10. "Push-Pull" Factors Influencing International Student Destination Choice.

    ERIC Educational Resources Information Center

    Mazzarol, Tim; Soutar, Geoffrey N.

    2002-01-01

    Examined factors motivating international student choice of host country. Found that economic and social factors within the home country serve to "push" students abroad, while a variety of "pull" factors influence selection of a host country. (EV)

  11. Factors influencing birth control habits in Victoria.

    PubMed

    Selwood, T; Leeton, J

    1981-02-01

    A survey was conducted in March 1978 for the purpose of comparing the contraceptive habits of Melbourne and ex-Melbourne populations in Victoria. Of the 1312 records of sexually active persons collected in 1978, 1254 of those persons were between the ages of 15 and 49. Recorded information included age, sex, marital status, and place of domicile (Melbourne or ex-Melbourne, Victoria). When the Melbourne population was compared with the rest of Victoria, the proportion using each method of contraception was much the same for each group. A marked difference was the proportion using withdrawal in Melbourne; this was over 3 times the proportion among the ex-Melbourne population. Over 35% of persons under age 30 used oral contraceptives (OCs), compared with 24.2 in the over 30 age range. Barrier methods and natural family planning methods and withdrawal were commonly used by the older age groups. A large proportion of the over age 30 group used sterilization and hysterectomy as forms of birth control. Individuals in "de facto" relationships showed a tendency towards more reliable forms of contraception than did other groups. Only 20.3% were not using some form of contraception. Single persons were frequent OC users and users of barrier methods. 28.1% used no form of contraception. The sex of the person interviewed in the survey revealed a bias. Males tended to report male birth control methods and female reported female methods rather than those used by partners of the opposite sex. Marital status influenced birth control choice. The choice of birth control for each marital status was influenced by the confounding factor of mean age of each group. PMID:7247847

  12. Factors affecting variation of different measures of cheese yield and milk nutrient recovery from an individual model cheese-manufacturing process.

    PubMed

    Cipolat-Gotet, C; Cecchinato, A; De Marchi, M; Bittante, G

    2013-01-01

    procedure was used to process individual milk samples obtained from 1,167 Brown Swiss cows reared in 85 herds of the province of Trento (Italy). The assessed traits exhibited almost normal distributions, with the exception of REC(FAT). The average values (± SD) were as follows: %CY(CURD)=14.97±1.86, %CY(SOLIDS)=7.18±0.92, %CY(WATER)=7.77±1.27, dCY(CURD)=3.63±1.17, dCY(SOLIDS)=1.74±0.57, dCY(WATER)=1.88±0.63, REC(FAT)=89.79±3.55, REC(PROTEIN)=78.08±2.43, REC(SOLIDS)=51.88±3.52, and REC(ENERGY)=67.19±3.29. All traits were highly influenced by herd-test-date and days in milk of the cow, moderately influenced by parity, and weakly influenced by the utilized vat. Both %CY(CURD) and dCY(CURD) depended not only on the fat and protein (casein) contents of the milk, but also on their proportions retained in the curd; the water trapped in curd presented an higher variability than that of %CY(SOLIDS). All REC traits were variable and affected by days in milk and parity of the cows. The described model cheese-making procedure and the results obtained provided new insight into the phenotypic variation of cheese yield and recovery traits at the individual level. PMID:24094531

  13. Exposure to milk or water at preschool lunch for 3 months influences children's choice of elementary school lunch drink 4 months later.

    PubMed

    Koivisto, U K; Edlund, B; Sjödén, P O

    1994-12-01

    The purpose was to study if serving milk or water with the lunch at preschool influenced 6- to 7-year-old children's preferences for and later choice between milk and water at lunch in elementary school later. Children (n = 147) at 12 daycare centres were usually served water at lunch but, for 3 months, six randomly chosen centres served milk at lunch (Intervention group) and six matched centres continued serving water (Control group). The groups did not differ with respect to preferences for seven types of beverages (including water and four varieties of milk) either before or after the intervention. Four and 12 months later, their choice of lunch drink (milk or water) at school was studied for two 5-week periods. At the 4-month assessment, the children in the Intervention group chose milk at lunch significantly more often than did those in the Control group (92% vs. 81% of the days), while there were no significant differences at 12 months (85% vs. 81%). Since there were no demonstrable effects on preferences, one interpretation of the results is that children tend to associate the type of drink regularly served at a meal with that specific meal. PMID:7726544

  14. Influence of temperature and fat content on ideal sucrose concentration, sweetening power, and sweetness equivalence of different sweeteners in chocolate milk beverage.

    PubMed

    Paixão, J A; Rodrigues, J B; Esmerino, E A; Cruz, A G; Bolini, H M A

    2014-12-01

    The introduction of new products catering to specific dietary needs and the corresponding changes in the consumer profile reflect a growing demand for diet and “light” products. However, little information is available regarding the sensory effects of different sweeteners in products consumed at different temperatures and with varying fat contents. In this regard, this study aimed to determine the influence of temperature and fat content on the ideal sucrose concentration and the sweetness equivalence and sweetening power of different sweeteners: Neotame (NutraSweet Corp., Chicago, IL), aspartame, neosucralose, sucralose, and stevia (95% rebaudioside A), with sucrose as reference, in a chocolate milk beverage using a just-about-right (JAR) scale and magnitude estimation. Increasing temperature of consumption had an inverse effect on the ideal sucrose concentration in whole milk beverages, whereas no difference was noted in beverages made skim milk. In addition, a decrease in sweetening power was observed for all of the sweeteners analyzed considering the same conditions. The findings suggest that different optimal conditions exist for consumption of chocolate milk beverage related to sweetness perception, which depends on the fat level of milk used in the formulation. This information can be used by researchers and dairy processors when developing chocolate milk beverage formulations. PMID:25606602

  15. Measurement of bovine somatotropin (bST) and insulin-like growth factor-1 (IGF-1) in bovine milk using an electrochemiluminescent assay.

    PubMed

    McGrath, Michael F; Bogosian, Gregg; Fabellar, Anabella C; Staub, Robin L; Vicini, John L; Widger, Leslie A

    2008-08-27

    Bovine somatotropin (bST) and insulin-like growth factor-1 (IGF-1) are peptide hormones that are involved in the regulation of milk production in dairy cows. Because these hormones are present at extremely low concentration in fresh and processed bovine milk, a highly sensitive and specific electrochemiluminescent immunoassay (ECLIA) has been developed to better estimate the concentration of these hormones in milk. The assay employs an imager, a capture antibody bound to a carbon electrode, and a detection antibody coupled to a ruthenium label. In the presence of tripropylamine and an electric pulse, ruthenium generates light proportional to the amount of antigen bound, and the light is captured as signal by a charge-coupled device (CCD) camera. Using bovine milk as the starting matrix, 99.69% of bST and 104.79% of IGF-1 were recoverable. The limit of detection (LOD) was <5 pg/mL for bST and <1 pg/mL for IGF-1. The limit of quantification (LOQ) was <14 pg/mL for bST in milk and <2 pg/mL of IGF-1. The assay is highly specific and shows <0.2% cross-reactivity with other peptide hormones found in bovine milk such as insulin and IGF-2. These data indicate this new, ECLIA is highly sensitive and specific for estimating the concentration of bST or IGF-1 in milk. PMID:18671399

  16. Goat Milk Yoghurt by Using Lacto-B Culture Modulates the Production of Tumor Necrosis Factor-Alpha and Interleukin-10 in Malnourished Rats

    PubMed Central

    Kandarina, BJ. Istiti; Kusuma, Sari; Trisnasari, Yunita Dewi

    2014-01-01

    Total spleen lymphocytes, lymphocyte proliferation, tumor necrosis factor-α (TNF-α), and interleukin-10 (IL-10) in spleen lymphocyte culture were studied in malnourished Wistar rats fed with goat milk yoghurt. Malnourished rats were created by using standard feed restriction as much as 50% of normal rats for 21 d. Goat milk yoghurt containing three types of microorganism e.g., Lactobacillus acidophilus, Sterptococcus thermophilus and Bifidobacterium longum derived from Lacto-B culture in powder form. After 21 d, the rats continued to receive restricted feeding and supplemented with goat milk yoghurt for 7 d. Total splenocytes were counted by hemocytometer. Splenocytes proliferation was expressed as stimulation index, whereas the TNF-α and IL-10 of spleen lymphocyte culture were measured by ELISA technique. The total number of splenocytes and stimulation index of splenocytes in moderate malnourished and normal rats supplemented with goat milk yoghurt was not significantly different. The level of TNF-α in the rat supplemented with goat milk yoghurt was lower (p<0.05) than the control group, whereas the level of IL-10 in the rat supplemented with goat milk yoghurt was higher (p<0.05) than the control group. In conclusion, goat milk yoghurt supplementation in malnourished rats could decrease TNF-α as a representation of the proinflammatory cytokine, while it increases IL-10 as a representation of the anti-inflammatory cytokine. PMID:26760750

  17. Factors affecting life cycle assessment of milk produced on 6 Mediterranean buffalo farms.

    PubMed

    Pirlo, G; Carè, S; Fantin, V; Falconi, F; Buttol, P; Terzano, G M; Masoni, P; Pacelli, C

    2014-10-01

    This study quantifies the environmental impact of milk production of Italian Mediterranean buffaloes and points out the farm characteristics that mainly affect their environmental performance. Life cycle assessment was applied in a sample of 6 farms. The functional unit was 1 kg of normalized buffalo milk (LBN), with a reference milk fat and protein content of 8.3 and 4.73%, respectively. The system boundaries included the agricultural phase of the buffalo milk chain from cradle to farm gate. An economic criterion was adopted to allocate the impacts on milk production. Impact categories investigated were global warming (GW), abiotic depletion (AD), photochemical ozone formation (PO), acidification (AC), and eutrophication (EU). The contribution to the total results of the following farm activities were investigated: (1) on-farm energy consumption, (2) manure management, (3) manure application, (4) on-farm feed production (comprising production and application of chemical fertilizers and pesticides), (5) purchased feed production, (6) enteric fermentation, and (7) transport of purchased feeds, chemical fertilizers, and pesticides from producers to farms. Global warming associated with 1 kg of LBN resulted in 5.07 kg of CO₂ Eq [coefficient of variation (CV)=21.9%], AD was 3.5 × 10(-3) kg of Sb Eq (CV=51.7%), PO was 6.8 × 10(-4) kg of C₂H₄ Eq (CV=28.8%), AC was 6.5 × 10(-2) kg of SO₂ Eq (CV=30.3%), and EU was 3.3 × 10(-2) kg of PO₄(3-) Eq (CV=36.5%). The contribution of enteric fermentation and manure application to GW is 37 and 20%, respectively; on-farm consumption, on-farm feed production, and purchased feed production are the main contributors to AD; about 70% of PO is due to enteric fermentation; manure management and manure application are responsible for 55 and 25% of AC and 25 and 55% of EU, respectively. Methane and N₂O are responsible for 44 and 43% of GW, respectively. Crude oil consumption is responsible for about 72% of AD; contribution of

  18. Influence of dietary grape pomace combined with linseed oil on fatty acid profile and milk composition.

    PubMed

    Manso, T; Gallardo, B; Salvá, A; Guerra-Rivas, C; Mantecón, A R; Lavín, P; de la Fuente, M A

    2016-02-01

    Grape pomace is a by-product resulting from the winery industry that is rich in phenolic compounds. It could play a role as an antioxidant and, owing to its high fiber concentration, it would be an alternative ingredient to partially replace forage in the diet of small ruminants. The objective of this study was to evaluate the effect of dietary supplementation of vitamin E or different doses of grape pomace associated with linseed oil on milk fatty acid profile, composition, and yield. Forty-eight Churra ewes were fed with experimental diets consisting of a total mixed ration (TMR) containing 2.7% [on a dry matter (DM) basis] of linseed oil, forage, and concentrate at a 40:60 ratio. Ewes were assigned to 1 of 4 treatments: control (without grape pomace), vitamin E (with 500 mg/kg of TMR of vitamin E), grape pomace-5 (5 g/100 g of TMR of DM of grape pomace), and grape pomace-10 (10 g/100 g of TMR of DM of grape pomace). Experimental diets did not affect DM intake and milk yield and composition. The vitamin E supplementation had only a moderate effect on milk concentration of fatty acids (increase in α-linolenic acid and 16:0 and decrease in cis-9 18:1). Grape pomace supplementation did not affect the percentages of total saturated, monounsaturated, and polyunsaturated fatty acids. Levels of α-linolenic acid reached about 1% of total fatty acids as a consequence of the presence of linseed oil in the diets, were not modified with vitamin E, and remained unaltered in grape pomace-5 and -10 treatments. Linoleic acid was increased by the highest dose of grape pomace, but this ingredient did not modify the cis-9,trans-11 18:2 milk fat content. The concentration of total odd- and branched-chain fatty acids did not diminish in grape pomace-5 and pomace-10 treatments. The presence of grape residue did not modified the trans-11 18:1 and trans-10 18:1 contents, which might indicate that, under the conditions assayed, this winery by-product would not alter the pathways of

  19. Antioxidative activity of organic versus conventional milk

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Some dairy proteins exhibit antioxidative activity, a property used for marketing foods as beneficial to American consumers. However, factors in milk production and processing that influence this activity are not fully understood. In this study, commercially available homogenized and pasteurized mi...

  20. Antioxidative activity of organic versus conventional milk

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Some dairy proteins have been found to exhibit antioxidative activity, a property used for marketing foods as nutritionally beneficial to the American consumer. However, the factors in milk production and processing that influence this activity are not fully understood. In this study, commercially...

  1. What Factors Influence a Teacher's Commitment to Student Learning?

    ERIC Educational Resources Information Center

    Dannetta, Vincent

    2002-01-01

    Study of the personal, organizational, student-related factors influencing teacher commitment to student learning. Finds, for example, that among personal factors intrinsic rewards are more important than extrinsic rewards, that among organization factors collegiality is an important influence on commitment to student learning, and that among…

  2. Influence of Breastfeeding Time on Levels of Organochlorine Pesticides in Human Milk of a Mexican Population.

    PubMed

    Chávez-Almazán, Luis A; Diaz-Ortiz, Jesús; Alarcón-Romero, Mario; Davila-Vazquez, Gustavo; Saldarriaga-Noreña, Hugo; Sampedro-Rosas, Laura; López-Silva, Saúl; Santiago-Moreno, Agustín; Rosas-Acevedo, José L; Waliszewski, Stefan M

    2016-02-01

    This study was conducted with the objective of determining whether there is a depuration of organochlorine pesticides in breast milk according to breastfeeding time. In total, 171 samples from mothers that lived in the State of Guerrero, Mexico were analyzed. There was a weak negative relationship between pp'DDE (r = -0.216) and Σ-DDT (r = -0.222) concentrations with the days of lactation. In a comparison analysis, a statistically significant decrease of pp'DDT and pp'DDE levels was observed, as well as the Σ-DDT from the first to the fifth week of lactation. A reduction of 0.188 mg/kg lipid of pp'DDE and 0.181 mg/kg lipid of Σ-DDT per week was obtained. HCB, β-HCH and op'DDT concentrations were low and had no major fluctuations between subgroups. The low levels found and the observed reduction in time involve less exposure to the infant to these pollutants. Through this methodology changes in levels of certain organochlorine pesticides in various stages of human milk production may be shown. PMID:26602567

  3. [Microbiological colonisation of bovine teat canal--significance and influencing factors].

    PubMed

    Paduch, Jan-Hendrik; Krömker, Volker

    2011-01-01

    The teat canal of lactating dairy cattle is of particular importance for the defence of facultative pathogenic and pathogenic microorganisms (e.g., staphylococci) invading the bovine udder. Furthermore the canal is usually colonized with microorganisms, too. In addition to microorganisms inhibiting mastitis pathogens the teat canal is colonized by staphylococci. The microbial colonization can be influenced by the environment of the animals, the care and disinfection of the teat skin and indirectly by the effects of forces being associated with machine milking. Because of vacuum fluctuations occurring under the teat tip microorganisms, which colonize the teat canal, can invade the bovine mammary gland and cause infections there. This paper gives a review of the microbial colonization of the bovine teat duct and of influencing factors on the microbial populations as well as of the significance of the teat canal colonization for the development of mastitis. PMID:21465768

  4. Factors influencing the prevalence of subclinical mastitis in lactating dromedary camels in Riyadh Region, Saudi Arabia.

    PubMed

    Aljumaah, Riyadh S; Almutairi, Faris F; Ayadi, Moez; Alshaikh, Mohammad A; Aljumaah, Ali M; Hussein, Mansour F

    2011-12-01

    The purpose of this study was to determine the prevalence of subclinical mastitis in camels in Riyadh, Saudi Arabia and the factors influencing its incidence. A total of 740 quarter milk samples were collected from 47 camel herds belonging to Majahim, Maghatir, Shu'l, and Sufer breeds. California mastitis test (CMT) was used as a screening test for subclinical mastitis. Samples giving negative or trace CMT scores (0) were assigned to healthy quarters, while those giving positive scores of 1+ to 3+ were assigned to subclinically affected quarters. Logistic regression was used to assess the association of breed, parity, and stage of lactation with the prevalence of subclinical mastitis. Milk fat, protein, lactose, solid nonfat percentages and Na, Ca, and K concentrations were compared in CMT-positive versus healthy quarters. One third (33%) of tested quarters had subclinical mastitis based on CMT. The estimated probability of subclinical mastitis with the combined effects of breed, parity, and stage of lactation ranged from 15.8% to 54.6%. The risk of subclinical mastitis increased significantly with parity and with the early stage of lactation. The Shu'l breed had significantly higher prevalence of subclinical mastitis than other breeds. Significant decreases in protein, lactose, and solid nonfat, Ca and K concentrations and increase in Na concentrations were associated with subclinical mastitis. In conclusion, subclinical mastitis is prevalent in Saudi camels, and its incidence is influenced by breed, parity, and stage of lactation. PMID:21637994

  5. Milk Allergy

    MedlinePlus

    ... How Can I Help a Friend Who Cuts? Milk Allergy KidsHealth > For Teens > Milk Allergy Print A ... on to find out. What Happens With a Milk Allergy? Food allergies involve the body's immune system, ...

  6. The character of Queso and health-related compounds found in milk

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Research conducted by the Milk & Cheese group focuses on understanding the factors that influence the quality traits of cheese and health-value of milk. Our research to understand and enhance the character traits and processing nuances of the Hispanic-style cheese, Queso Chihuahua (QC), involved the...

  7. Factors influencing informal care-giving.

    PubMed

    Holmes, Ann M.; Deb, Partha

    1998-07-01

    BACKGROUND: As downsizing of institutional care continues, patients discharged are likely to have more severe mental illnesses, and to have experienced longer tenures within institutions than patients who have been discharged in the past. As greater numbers of patients are removed from mental hospitals, the objective burden experienced by informal care-givers may increase, particularly if formal care levels are inadequate. AIMS OF THE STUDY: This paper documents who assumes informal care-giver roles, and the form such care-giving takes for patients discharged from a state hospital. Specifically, this paper identifies (i) what factors affect a person's decision to assume a care-giver role, including the participation of other network members in care-giving, (ii) what factors influence whether care-giving is provided in time or in direct purchase of care and (iii) how the patient's treatment location affects the decision of the network member to assume any care-giving role. DATA AND ANALYTICAL METHODS: Data for this paper are taken from a longitudinal study of the closure of a state mental hospital in central Indiana. Seventy-seven patients were asked to identify their community networks. Ninety-eight network members were surveyed about the informal care, both in time or through direct expenditures, they provided to these patients one year after discharge. Care-giving relationships were estimated using a multivariate probit model. Such a model estimates the extent to which the decision to provide care in either form depends on the care-giving activities assumed by other network members associated with a given patient, as well as the characteristics of individual patients and network members. RESULTS: Forty-one per cent of network members provided some level of informal care, with 13.3% providing some care in time, and 35.7% providing some care through direct expenditures. A positive relationship was found between participation in informal care-giving and the

  8. Genetic variants and effects on milk traits of the caprine paired-like homeodomain transcription factor 2 (PITX2) gene in dairy goats.

    PubMed

    Zhao, Haiyu; Wu, Xianfeng; Cai, Hanfang; Pan, Chuanying; Lei, Chuzhao; Chen, Hong; Lan, Xianyong

    2013-12-15

    The paired-like homeodomain transcription factor 2 (PITX2) gene plays a critical role in cell proliferation, differentiation, hematopoiesis and organogenesis. This gene regulates several genes' expressions in the Wnt/beta-catenin and POU1F1 pathways, thereby probably affecting milk performance. The goal of this study was to characterize the genetic variants of the PITX2 gene and test their associations with milk traits in dairy goats. Herein, four novel single nucleotide polymorphisms (SNPs), AC_000163:g.18117T>C, g.18161C>G, g.18322C>A and g.18353T>C, within the caprine PITX2 gene, were found in two famous Chinese dairy goat breeds. These SNPs mapping at Cys28Arg, Pro42Pro, IVS1+79C>A and IVS1+110T>C, were genotyped by the MvaI, SmaI, MspI and RsaI aCRS-RFLP or PCR-RFLP methods, respectively. Accordingly, two main haplotypes (CGCT and CGCC) were identified among the specimens. Association testing revealed that the SmaI and RsaI polymorphisms were significantly associated with the milk fat content, milk lactose content and milk density (P<0.05 or P<0.01) in the Guanzhong (GZ) dairy goats, respectively. At the same time, the RsaI locus was also found to significantly link to the second lactation milk yield, milk fat content, milk lactose content, milk density and milk total solid content (P<0.05 or P<0.01) in the Xinong Saanen (XNSN) dairy goats, respectively. These results indicated that the caprine PITX2 gene had the significant effects on milk traits. Hence, the RsaI and SmaI loci could be regarded as two DNA markers for selecting superior milk performance in dairy goats. These preliminary findings not only would extend the spectrum of genetic variation of the goat PITX2 gene, but also would contribute to implementing marker-assisted selection (MAS) in breeding and genetics in dairy goats. PMID:24076438

  9. Global influences on milk purchasing in New Zealand – implications for health and inequalities

    PubMed Central

    Smith, Moira B; Signal, Louise

    2009-01-01

    Background Economic changes and policy reforms, consistent with economic globalization, in New Zealand in the mid-1980s, combined with the recent global demand for dairy products, particularly from countries undergoing a 'nutrition transition', have created an environment where a proportion of the New Zealand population is now experiencing financial difficulty purchasing milk. This situation has the potential to adversely affect health. Discussion Similar to other developed nations, widening income disparities and health inequalities have resulted from economic globalization in New Zealand; with regard to nutrition, a proportion of the population now faces food poverty. Further, rates of overweight/obesity and chronic diseases have increased in recent decades, primarily affecting indigenous people and lower socio-economic groups. Economic globalization in New Zealand has changed the domestic milk supply with regard to the consumer and may shed light on the link between globalization, nutrition and health outcomes. This paper describes the economic changes in New Zealand, specifically in the dairy market and discusses how these changes have the potential to create inequalities and adverse health outcomes. The implications for the success of current policy addressing chronic health outcomes is discussed, alternative policy options such as subsidies, price controls or alteration of taxation of recommended foods relative to 'unhealthy' foods are presented and the need for further research is considered. Summary Changes in economic ideology in New Zealand have altered the focus of policy development, from social to commercial. To achieve equity in health and improve access to social determinants of health, such as healthy nutrition, policy-makers must give consideration to health outcomes when developing and implementing economic policy, both national and global. PMID:19152688

  10. Early milk feeding influences taste acceptance and liking during infancy12345

    PubMed Central

    Mennella, Julie A; Forestell, Catherine A; Morgan, Lindsay K; Beauchamp, Gary K

    2009-01-01

    Background: We identified a model system that exploits the inherent taste variation in early feedings to investigate food preference development. Objective: The objective was to determine whether exposure to differing concentrations of taste compounds in milk and formulas modifies acceptance of exemplars of the 5 basic taste qualities in a familiar food matrix. Specifically, we examined the effects of consuming hydrolyzed casein formulas (HCFs), which have pronounced bitter, sour, and savory tastes compared with breast milk (BM) and bovine milk–based formulas (MFs), in which these taste qualities are weaker. Design: Subgroups of BM-, MF- and HCF-fed infants, some of whom were fed table foods, were studied on 6 occasions to measure acceptance of sweet, salty, bitter, savory, sour, and plain cereals. Results: In infants not yet eating table foods, the HCF group ate significantly more savory-, bitter-, and sour-tasting and plain cereals than did the BM or MF groups. HCF infants displayed fewer facial expressions of distaste while eating the bitter and savory cereals, and they and BM infants were more likely to smile while they were eating the savory cereal. In formula-fed infants eating table foods, preferences for the basic tastes reflected the types of foods they were being fed. In general, those infants who ate more food displayed fewer faces of distaste. Conclusions: The type of formula fed to infants has an effect on their response to taste compounds in cereal before solid food introduction. This model system of research investigation sheds light on sources of individual differences in taste and perhaps cultural food preferences. PMID:19605570

  11. Recovery of extracellular vesicles from human breast milk is influenced by sample collection and vesicle isolation procedures.

    PubMed

    Zonneveld, Marijke I; Brisson, Alain R; van Herwijnen, Martijn J C; Tan, Sisareuth; van de Lest, Chris H A; Redegeld, Frank A; Garssen, Johan; Wauben, Marca H M; Nolte-'t Hoen, Esther N M

    2014-01-01

    Extracellular vesicles (EV) in breast milk carry immune relevant proteins and could play an important role in the instruction of the neonatal immune system. To further analyze these EV and to elucidate their function it is important that native populations of EV can be recovered from (stored) breast milk samples in a reproducible fashion. However, the impact of isolation and storage procedures on recovery of breast milk EV has remained underexposed. Here, we aimed to define parameters important for EV recovery from fresh and stored breast milk. To compare various protocols across different donors, breast milk was spiked with a well-defined murine EV population. We found that centrifugation of EV down into density gradients largely improved density-based separation and isolation of EV, compared to floatation up into gradients after high-force pelleting of EV. Using cryo-electron microscopy, we identified different subpopulations of human breast milk EV and a not previously described population of lipid tubules. Additionally, the impact of cold storage on breast milk EV was investigated. We determined that storing unprocessed breast milk at -80°C or 4°C caused death of cells present in breast milk, leading to contamination of the breast milk EV population with storage-induced EV. Here, an alternative method is proposed to store breast milk samples for EV analysis at later time points. The proposed adaptations to the breast milk storage and EV isolation procedures can be applied for EV-based biomarker profiling of breast milk and functional analysis of the role of breast milk EV in the development of the neonatal immune system. PMID:25206958

  12. Recovery of extracellular vesicles from human breast milk is influenced by sample collection and vesicle isolation procedures

    PubMed Central

    Zonneveld, Marijke I.; Brisson, Alain R.; van Herwijnen, Martijn J. C.; Tan, Sisareuth; van de Lest, Chris H. A.; Redegeld, Frank A.; Garssen, Johan; Wauben, Marca H. M.; Nolte-'t Hoen, Esther N. M.

    2014-01-01

    Extracellular vesicles (EV) in breast milk carry immune relevant proteins and could play an important role in the instruction of the neonatal immune system. To further analyze these EV and to elucidate their function it is important that native populations of EV can be recovered from (stored) breast milk samples in a reproducible fashion. However, the impact of isolation and storage procedures on recovery of breast milk EV has remained underexposed. Here, we aimed to define parameters important for EV recovery from fresh and stored breast milk. To compare various protocols across different donors, breast milk was spiked with a well-defined murine EV population. We found that centrifugation of EV down into density gradients largely improved density-based separation and isolation of EV, compared to floatation up into gradients after high-force pelleting of EV. Using cryo-electron microscopy, we identified different subpopulations of human breast milk EV and a not previously described population of lipid tubules. Additionally, the impact of cold storage on breast milk EV was investigated. We determined that storing unprocessed breast milk at −80°C or 4°C caused death of cells present in breast milk, leading to contamination of the breast milk EV population with storage-induced EV. Here, an alternative method is proposed to store breast milk samples for EV analysis at later time points. The proposed adaptations to the breast milk storage and EV isolation procedures can be applied for EV-based biomarker profiling of breast milk and functional analysis of the role of breast milk EV in the development of the neonatal immune system. PMID:25206958

  13. Do farm audits improve milk quality?

    PubMed

    Flores-Miyamoto, A; Reij, M W; Velthuis, A G J

    2014-01-01

    Milk quality is assessed using bulk milk analysis and by farm audits in the Netherlands. However, the extent of the effect that dairy farm audits have on milk quality is unknown. Data from over 13,000 audits performed on 12,855 dairy farms from February 2006 to April 2008 were merged with laboratory test results of 325,150 bulk milk samples collected 6 mo before and after the audit. A linear mixed model with the method of restricted maximum likelihood was conducted to study whether the total bacterial counts (TBC) of bulk milk were lower during the periods before and after the dairy farm audit. Results showed that TBC values were 2 to 6% lower (i.e., 0.010 to 0.026 log cfu/mL) for a period from 1.5 to at least 6 mo after an audit. Additionally, several variables were significantly associated with bulk milk TBC values: seasonality, total number of attention points (given if some checklist points were not appropriate), audit type, audit result, and the categories milking equipment maintenance, and utility room-tank maintenance. The TBC values increased with a higher level of attention points. Furthermore, the farms rejected based on the audit results had the highest average TBC values and the approved farms had the lowest values. If dairy farms had an overall negative audit assessment and consequently needed a re-audit in the following year, the TBC values of bulk milk were more likely to be higher. Auditing may provide dairy farmers the opportunity to receive advice about factors that influence bulk milk TBC values, for a period of at least 6 mo following the audit. PMID:24183685

  14. Raw Milk Consumption

    PubMed Central

    Lucey, John A.

    2015-01-01

    There continues to be considerable public debate on the possible benefits regarding the growing popularity of the consumption of raw milk. However, there are significant concerns by regulatory, or public health, organizations like the Food and Drug Administration and the Centers for Disease Control and Prevention because of risk of contracting milkborne illnesses if the raw milk is contaminated with human pathogens. This review describes why pasteurization of milk was introduced more than 100 years ago, how pasteurization helped to reduce the incidence of illnesses associated with raw milk consumption, and the prevalence of pathogens in raw milk. In some studies, up to a third of all raw milk samples contained pathogens, even when sourced from clinically healthy animals or from milk that appeared to be of good quality. This review critically evaluates some of the popularly suggested benefits of raw milk. Claims related to improved nutrition, prevention of lactose intolerance, or provision of “good” bacteria from the consumption of raw milk have no scientific basis and are myths. There are some epidemiological data that indicate that children growing up in a farming environment are associated with a decreased risk of allergy and asthma; a variety of environmental factors may be involved and there is no direct evidence that raw milk consumption is involved in any “protective” effect. PMID:27340300

  15. Factors influencing wetland use by Canada geese

    USGS Publications Warehouse

    Naugle, D.E.; Gleason, J.S.; Jenks, J.A.; Higgins, K.F.; Mammenga, P.W.; Nusser, S.M.

    1997-01-01

    Seasonal and semi-permanent wetlands in eastern South Dakota were surveyed in 1995 and 1996 to identify habitat characteristics influencing wetland use by Canada geese (Branta canadensis maxima). Position of a wetland within the landscape and its area were important landscape-scale features influencing wetland use by geese. Our delineation of potential Canada goose habitat using a wetland geographic information system indicated that distribution and area of semi-permanent wetlands likely limit Canada goose occurrence in regions outside the Prairie Coteau. Periodicity in hydrologic cycles within landscapes also may influence goose use of wetlands in eastern South Dakota.

  16. Milk-borne campylobacter infection.

    PubMed Central

    Robinson, D A; Jones, D M

    1981-01-01

    The common factor in 13 recent outbreaks of Campylobacter jejuni enteritis was the consumption of unpasteurised or incompletely pasteurised milk. C jejuni is a common commensal in the alimentary tract of milking cows, but it is not clear how the milk becomes contaminated with the organism. Pasteurisation will readily eliminate the organism from milk. In England and Wales 3% of milk retailed is still unpasteurised, and in the light of these findings it is suggested that only pasteurised milk should be sold to the public. PMID:6786504

  17. Human milk: mother nature's prototypical probiotic food?

    PubMed

    McGuire, Michelle K; McGuire, Mark A

    2015-01-01

    The concept of "probiotic" is generally attributed to Dr. Ilya Mechnikov, who hypothesized that longevity could be enhanced by manipulating gastrointestinal microbes using naturally fermented foods. In 2001, a report of the FAO and WHO (2001 Oct, http://www.who.int/foodsafety/publications/fs_-management/en/probiotics.pdf) proposed a more restrictive definition of probiotic, as follows: "a live micro-organism which, when administered in adequate amounts, confers a health benefit on the host." As such, answering the fundamental question posed here-"Is human milk a probiotic?"-requires first grappling with the concept and meaning of the term probiotic. Nonetheless, one must also be convinced that human milk contains bacteria. Indeed, there are scores of publications providing evidence of a paradigm shift in this regard. Variation in the human-milk microbiome may be associated with maternal weight, mode of delivery, lactation state, gestation age, antibiotic use, and maternal health. Milk constituents (e.g., fatty acids and complex carbohydrates) might also be related to the abundance of specific bacterial taxa in milk. Whether these bacteria affect infant health is likely, but more studies are needed to test this hypothesis. In summary, a growing literature suggests that human milk, like all other fluids produced by the body, indeed contains viable bacteria. As such, and recognizing the extensive literature relating breastfeeding to optimal infant health, we propose that human milk should be considered a probiotic food. Determining factors that influence which bacteria are present in milk and if and how they influence the mother's and/or the recipient infant's health remain basic science and public health realms in which almost nothing is known. PMID:25593150

  18. Epidermal Growth Factor and Parathyroid Hormone-related Peptide mRNA in the Mammary Gland and their Concentrations in Milk

    PubMed Central

    Bruder, E. D.; Van Hoof, J.; Young, J. B.; Raff, H.

    2008-01-01

    The physiological adaptations of the neonatal rat to hypoxia from birth include changes in gastrointestinal function and intermediary metabolism. We hypothesized that the hypoxic lactating dam would exhibit alterations in mammary gland function leading to changes in the concentration of milk peptides that are important in neonatal gastrointestinal development. The present study assessed the effects of chronic hypoxia on peptides produced by the mammary glands and present in milk. Chronic hypoxia decreased the concentration of epidermal growth factor (EGF) in expressed milk and pup stomach contents and decreased maternal mammary gland Egf mRNA. The concentration of parathyroid hormone-related protein (PTHrp) was unchanged in milk and decreased in pup stomach contents; however, mammary Pthlh mRNA was increased by hypoxia. There was a significant increase in adiponectin concentrations in milk from hypoxic dams. Chronic hypoxia decreased maternal body weight, and pair feeding normoxic dams an amount of food equivalent to hypoxic dam food intake decreased body weight to an equivalent degree. Decreased food intake did not affect the expression of Egf, Pthlh, or Lep mRNA in mammary tissue. The results indicated that chronic hypoxia modulated mammary function independently of hypoxia-induced decreases in maternal food intake. Decreased EGF and increased adiponectin concentrations in milk from hypoxic dams likely affect the development of neonatal intestinal function. PMID:18401831

  19. Milk quality and automatic milking: fat globule size, natural creaming, and lipolysis.

    PubMed

    Abeni, F; Degano, L; Calza, F; Giangiacomo, R; Pirlo, G

    2005-10-01

    Thirty-eight Italian Friesian first-lactation cows were allocated to 2 groups to evaluate the effect of 1) an automatic milking system (AMS) vs. milking in a milking parlor (MP) on milk fat characteristics; and 2) milking interval (< or =480, 481 to 600, 601 to 720, and >720 min) on the same variables. Milk fat was analyzed for content (% vol/vol), natural creaming (% of fat), and free fatty acids (FFA, mEq/100 g of fat). Distribution of milk fat globule size was evaluated to calculate average fat globule diameter (d(1)), volume-surface average diameter (d(32)), specific globule surface area, and mean interglobular distance. Milk yield was recorded to calculate hourly milk and milk fat yield. Milking system had no effect on milk yield, milk fat content, and hourly milk fat yield. Milk from AMS had less natural creaming and more FFA content than milk from MP. Fat globule size, globular surface area, and interglobular distance were not affected by milking system per se. Afternoon MP milkings had more fat content and hourly milk fat yield than AMS milkings when milking interval was >480 min. Milk fat FFA content was greater in AMS milkings when milking interval was < or =480 min than in milkings from MP and from AMS when milking interval was >600 min. Milking interval did not affect fat globule size, expressed as d32. Results from this experiment indicate a limited effect of AMS per se on milk fat quality; a more important factor seems to be the increase in milking frequency, generally associated with AMS. PMID:16162526

  20. Marketing Factors Influencing the Overall Satisfaction of Marriage Education Participants.

    ERIC Educational Resources Information Center

    Morris, Michael Lane; Cooper, Catherine; Gross, Kevin H.

    1999-01-01

    Seventy-one married couples attending marriage education workshops were surveyed regarding price, product, place, people, and promotional marketing factors influencing their overall satisfaction as workshop participants. Findings suggest both similar and unique marketing factors influenced husbands' and wives' satisfaction. Recommendations for…

  1. The Macrostructure of Milk Lipids: The Fat Globules.

    PubMed

    Martini, Mina; Salari, Federica; Altomonte, Iolanda

    2016-05-18

    The aim of this review article is to summarize the information available related to milk fat globules (MFGs) in order to highlight their contribution to the nutritional and technological characteristics of milk and dairy products. The macrostructure of milk lipids is composed of globules made up of triglycerides with different melting points, enveloped by a biological membrane from the mammary epithelial cell. In milks of different animal species, there are different-sized MFGs, ranging from diameters of less than 0.2 μm to a maximum of 15 μm. The average diameter and the number of globules are affected by endogenous, physiological, and exogenous factors. The size of the globules in turn affects the qualitative characteristics of milk and cheese. In addition, the average diameter of the globules and their surface that is exposed to the digestive system affect fat digestibility in different ways. Finally, the components of the MFG membranes have been shown to take part in the secretion process of globules and to have a beneficial effect on human health. In conclusion, by acting on factors influencing the dimensions of the fat globules and by increasing the content of the milk membrane could help adapt milk production to specific consumer targets and improve milk nutritional properties. PMID:24915408

  2. Climatic conditions, twining and frequency of milking as factors affecting the risk of fetal losses in high-yielding Holstein cows in a hot environment.

    PubMed

    Mellado, Miguel; López, Ricardo; de Santiago, Ángeles; Veliz, Francisco G; Macías-Cruz, Ulises; Avendaño-Reyes, Leonel; García, José Eduardo

    2016-08-01

    An epidemiological study of risk factors for fetal losses was carried out on 62,403 high-yielding Holstein cows in 29 large highly technified dairy herds in northern Mexico (25° N; 23.5 °C mean annual temperature). Multivariate multiple-group response model indicated that fetal losses between 43 and 260 days of pregnancy were 23 %. Heat-stressed cows at conception (temperature-humidity index, THI >82) were 14 times more likely (P < 0.01) to present fetal losses than not heat-stressed cows (27 vs. 18 %). Heat-stressed cows at 60 days of pregnancy (THI >82) were 4.5 times more likely (P < 0.01) to present fetal losses than cows suffering heat stress in early gestation (29.1 vs. 17.7 %). The proportion of cows experiencing fetal loss was lower for multiparous than primiparous cows (odds ratio; OR = 0.7). Cows with twin pregnancies had significantly increased chances of losing their fetuses than cows with a single fetus (33.6 vs. 20.7 %; P < 0.01). Cows with three milkings per day were 30 % more likely (P < 0.01) to lose their fetuses than cows milked twice daily. Cows calving in winter and spring had significantly increased chances of losing their fetuses than cows calving in summer and fall (30-35 vs. 4-5 %; P < 0.01). It was concluded that, in this particular environment, heat stress exert a great influence on fetal losses in high producing Holstein cows. PMID:27225752

  3. Nutritional and Hygienic Quality of Raw Milk in the Mid-Northern Region of Algeria: Correlations and Risk Factors

    PubMed Central

    Adjlane-Kaouche, Soumeya; Benhacine, Rafik; Ghozlane, Faiçal; Mati, Abderrahmane

    2014-01-01

    This paper aims to study the overall quality of raw milk in the mid-northern region of Algeria. The analysis results showed a decrease in the average temperature for the delivery of 1,54°C with P<0.001. However, no significant variation (P>0.05) was observed in almost all the physical and nutritional parameters studied (pH, fat content, and protein content) between M1 and M2. The average contamination by total mesophilic aerobic bacteria (TMAB), coliforms, yeasts, molds, and different pathogens in samples taken at M1 showed significant changes at M2. This was confirmed by the decrease of reduction time of methylene blue (RTMB), about 54%. The variation was described as follows: (P>0.05) for yeasts and (P<0.05) for molds in M1 and M2, (P<0.05) for TMAB in M1, and (P<0.001) for TC, FC, and TMAB in M2. The analysis for the detection of Salmonella spp. showed no contamination in all samples tested, while antibiotic residues were detected in 35% of milks delivered. In conclusion, several risk factors have been identified in this study, namely, the effect of the season and the distance between the farm and the dairy unit. PMID:25374932

  4. Nutritional and hygienic quality of raw milk in the mid-northern region of Algeria: correlations and risk factors.

    PubMed

    Adjlane-Kaouche, Soumeya; Benhacine, Rafik; Ghozlane, Faiçal; Mati, Abderrahmane

    2014-01-01

    This paper aims to study the overall quality of raw milk in the mid-northern region of Algeria. The analysis results showed a decrease in the average temperature for the delivery of 1,54°C with P<0.001. However, no significant variation (P>0.05) was observed in almost all the physical and nutritional parameters studied (pH, fat content, and protein content) between M1 and M2. The average contamination by total mesophilic aerobic bacteria (TMAB), coliforms, yeasts, molds, and different pathogens in samples taken at M1 showed significant changes at M2. This was confirmed by the decrease of reduction time of methylene blue (RTMB), about 54%. The variation was described as follows: (P>0.05) for yeasts and (P<0.05) for molds in M1 and M2, (P<0.05) for TMAB in M1, and (P<0.001) for TC, FC, and TMAB in M2. The analysis for the detection of Salmonella spp. showed no contamination in all samples tested, while antibiotic residues were detected in 35% of milks delivered. In conclusion, several risk factors have been identified in this study, namely, the effect of the season and the distance between the farm and the dairy unit. PMID:25374932

  5. Insulin-like growth factor-I and insulin-like growth factor binding proteins in the bovine mammary gland: Receptors, endogenous secretion, and appearance in milk

    SciTech Connect

    Campbell, P.G.

    1988-01-01

    This is the first study to characterize both insulin-like growth factor-I (IGF-I) and insulin-like growth factor binding proteins (IGFBPs) in bovine milk, to characterize the IGF-I receptor in the dry and lactating mammary gland, and to report de novo synthesis and secretion of IGF-I and IGFBP from normal mammary tissue. Immunoreactive IGF-I was principally associated with 45 kDa IGFBP in milk. Multiparous cows had a higher IGF-I concentration of 307 ng/ml than primiparous cows at 147 ng/ml. IGF-I concentration on day 56 of lactation was 34 ng/ml for combined parity groups. At parturition, IGF-I mass in blood and milk pools was 1.4 and 1.2 mg, respectively. Binding of {sup 125}I-IGF-I was specific for IGF-I with anIC{sub 50} of 2.2 ng which was a 10- and 1273-fold greater affinity than IGF-II and insulin, respectively. Association constants, as determined by Scatchard analysis, were similar for both pregnant and lactating cows at 3.5 and 4.0 L/nM, respectively. In addition, estimated mean receptor concentration was 0.25 and 0.23 pM/mg protein for pregnant and lactating cows, respectively. In a survey of mammary microscomes prepared from 48 cows, {sup 125}I-IGF-I binding declined with progressing lactation and a similar trend was observed during pregnancy.

  6. Is Subjective Status Influenced by Psychosocial Factors?

    ERIC Educational Resources Information Center

    Lundberg, Johanna; Kristenson, Margareta

    2008-01-01

    Objective: Associations between subjective status and health are still relatively unexplored. This study aimed at testing whether subjective status is uniquely confounded by psychosocial factors compared to objective status, and what factors that may predict subjective status. Design: A cross-sectional analysis of a population-based, random sample…

  7. Factors Influencing Career Choice among Police Recruits

    ERIC Educational Resources Information Center

    Cole, Bryan

    2012-01-01

    This quantitative, non-experimental study examined the career choice factors of 154 (n = 154) police recruits to determine a correlation of age group generation to the five career choice factors presented in the Sibson Reward of Work Model. Law enforcement agencies faced a shortage of viable candidates to fill vacant positions. While extensive…

  8. Factors Influencing Simultaneous Communication Behaviors in Teachers.

    ERIC Educational Resources Information Center

    Stewart, David A.; And Others

    1988-01-01

    Simultaneous communication used by four teachers in formal lessons was investigated, to determine the extent to which signs and speech matched and to delineate factors predicting communication behavior. Simultaneous communication was found to be sign-driven or speech-driven depending on factors such as student comprehension, teacher's expertise,…

  9. Changes in human gut microbiota influenced by probiotic fermented milk ingestion.

    PubMed

    Unno, Tatsuya; Choi, Jung-Hye; Hur, Hor-Gil; Sadowsky, Michael J; Ahn, Young-Tae; Huh, Chul-Sung; Kim, Geun-Bae; Cha, Chang-Jun

    2015-06-01

    We investigated the effect of consuming probiotic fermented milk (PFM) on the microbial community structure in the human intestinal tract by using high-throughput barcoded pyrosequencing. Six healthy adults ingested 2 servings of PFM daily for 3 wk, and their fecal microbiota were analyzed before and after 3 wk of PFM ingestion period and for another 3 wk following the termination of PFM ingestion (the noningestion period). Fecal microbial communities were characterized by sequencing of the V1-V3 hypervariable regions of the 16S rRNA gene. All subjects showed a similar pattern of microbiota at the phylum level, where the relative abundance of Bacteriodetes species increased during the PFM ingestion period and decreased during the noningestion period. The increase in Bacteroidetes was found to be due to an increase in members of the families Bacteroidaceae or Prevotellaceae. In contrast to PFM-induced adaptation at the phylum level, the taxonomic composition at the genus level showed a considerable alteration in fecal microbiota induced by PFM ingestion. As revealed by analysis of operational taxonomic units (OTU), the numbers of shared OTU were low among the 3 different treatments (before, during, and after PFM ingestion), but the abundance of the shared OTU was relatively high, indicating that the majority (>77.8%) of total microbiota was maintained by shared OTU during PFM ingestion and after its termination. Our results suggest that PFM consumption could alter microbial community structure in the gastrointestinal tract of adult humans while maintaining the stability of microbiota. PMID:25864056

  10. Influence of fat and emulsifiers on the efficacy of nisin in inhibiting Listeria monocytogenes in fluid milk.

    PubMed

    Jung, D S; Bodyfelt, F W; Daeschel, M A

    1992-02-01

    The recent FDA affirmation of nisin, an antimicrobial peptide, as a GRAS (generally recognized as safe) additive in pasteurized cheese spreads has renewed interest in its potential application in US dairy products. Fluid milks were prepared with varying concentrations of milk fat (0 to 12.9%) and of nisin (0 to 50 U/ml). Biological activity assays using a sensitive indicator microorganism in a well diffusion system indicated that initial nisin activity (50 U/ml) decreased by about 33% when it was added to skim milk and by more than 88% when added to milk containing 12.9% fat. Nisin activity decreased by ca. 50% in milk containing 1.29% fat. Milks containing 0, 10, or 50 U/ml of nisin and varying fat percentages were challenged with approximately log10 7 to 7.5 cfu/ml of log phase Listeria monocytogenes Scott A or Jalisco. At 2 h after inoculation, the viable count of L. monocytogenes Scott A decreased to log10 .30 cfu/ml in skim milk with 50 U/ml of nisin, decreased to log10 2.90 cfu/ml in skim milk with 10 U/ml of nisin, and increased slightly (log10 7.8 cfu/ml) in skim milk without nisin. In half-and-half (12.9% milk fat), nisin was far less effective in inhibiting Listeria with populations decreasing to log10 6.57 cfu/ml for 10 U/ml of nisin and log10 5.87 cfu/ml for 50 U/ml. Similar results were obtained with L. monocytogenes Jalisco. The nonionic emulsifier, Tween 80, partially counteracted decreases of nisin activity in milks, whereas the anionic emulsifier, lecithin, had no effect. Addition of Tween 80 significantly increased the activity of nisin against L. monocytogenes in milk regardless of fat content. PMID:1560132

  11. Factors Influencing L2 Gender Processing

    ERIC Educational Resources Information Center

    Bordag, Denisa; Pechmann, Thomas

    2007-01-01

    In four experiments we explored processes underlying L2 gender retrieval. We focused on L1 interference and on the influence of the L2 noun's termination. In Experiments 1 and 2 we tried to manipulate the intensity of L1 interference. We found that L2 speakers cannot eliminate or substantially reduce the interlingual interference neither when they…

  12. Factors Influencing Curricular Reform; An Irish Perspective

    ERIC Educational Resources Information Center

    Ferris, Helena; Joyce, Pauline

    2015-01-01

    There are various influences and obstacles when planning an educational curriculum. The imprint of globalisation on the landscape of Irish medicine highlights the importance of delivering a diverse curriculum with international dimensions so that knowledge and skills can transfer across borders. It is also clear that medical emigration has a…

  13. Evaluation of on-farm veal calves' responses to unfamiliar humans and potential influencing factors.

    PubMed

    Leruste, H; Bokkers, E A M; Heutinck, L F M; Wolthuis-Fillerup, M; van der Werf, J T N; Brscic, M; Cozzi, G; Engel, B; van Reenen, C G; Lensink, B J

    2012-12-01

    The human-animal relationship is an important component of the welfare of farm animals and for this reason animal responsiveness tests to humans are included in on-farm welfare assessment schemes that provide indicators for this. However, apart from the behaviour of stockpersons towards their animals, other factors may also influence animals' reactivity to humans as observed through behavioural tests, which can add a further layer of complexity to the interpretation of test results. Knowledge of these factors may help a better interpretation of differences from one farm to another in the outcome of human-animal relationship tests, and may provide clues for improving the relationship between animals and humans. The main objective of this study was to identify whether management or environmental factors could influence the outcome of human-animal relationship tests in veal calves. Two tests were performed when calves were aged 14.9 ± 1.6 (SD) weeks in 148 veal farms: the voluntary approach of an unfamiliar human standing at the feeding fence and the reaction towards an unfamiliar human who entered the home pen and tried to touch each calf in a standardised way (Calf Escape Test (CET) - score 0 to 4). Questionnaires were filled in and interviews with the stockpersons were performed in order to obtain information on stockpersons, management, animal and building characteristics. The latency to touch an unfamiliar human at the feeding fence was significantly correlated with the CET scores. Total number of calves on the farm, space allowance, breed, environmental enrichment, stockperson's experience and season of observation influenced the percentage of calves that scored 0 in CET (i.e. calves that could not be approached). Type of milk distribution, type of breed and number of calves per stockperson influenced the percentage of calves that scored 4 in CET (i.e. calves could be touched). For both CET0 and CET4, the level of self-reported contacts by the stockperson

  14. Factors affecting application of milk allantoin as an estimator of microbial protein flow to the duodenum under commercial conditions.

    PubMed

    Schager, W M; Harrison, J H; Gaskins, C T; Davidson, D

    2003-05-01

    Three experiments were conducted to determine the effect of diet change, milk sampling technique, and bovine somatotropin (bST) on allantoin output in milk and the use of allantoin as a practical, noninvasive method for estimating microbial protein flow in dairy cattle. In experiment 1, four lactating Holstein cows were used in a 2 x 2 Latin square design with two treatments (ratio of forage to concentrate) and two periods. In experiment 2, six Holstein cows were used in a completely randomized design, and milk was collected by 1) a strip sample collected immediately before milking, 2) a strip sample collected 3 min from start of milking, and 3) a composite sample taken with an autosampler. In experiment three, 10 cows were used in a randomized block design to determine the effect of bST on milk allantoin. Milk samples were taken daily for 21 d, 7 d before, and 14 d after bST administration. In experiment 1, allantoin output (mmol/d) was significantly greater for cows fed the higher ratio of concentrate to forage, and there was a significant change in the amount of allantoin in milk 12 h (first subsequent milking) after a diet change. There was no difference in milk yield or dry matter intake between treatments. In experiment 2, no difference was detected in milk allantoin concentration among the three sampling methods. In experiment 3, milk yield, allantoin concentration, and total allantoin output was significantly increased after bST administration even though dry matter intake (DMI) remained unchanged. During the first 14 d following bST administration, estimates of microbial protein production derived from milk allantoin may be inaccurate due to increased milk production without an increase in DMI. PMID:12778582

  15. FACTORS AND PRACTICES THAT INFLUENCE LIVESTOCK DISTRIBUTION

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Inconsistent livestock distribution in extensive rangeland pastures continues as a vexing problem for land and livestock managers. Dispersal patterns of cattle are affected by abiotic factors like degree of slope, distance from water, shade, physical barriers, temperature extremes and precipitation...

  16. Chemotherapy, targeted agents, antiemetics and growth-factors in human milk: how should we counsel cancer patients about breastfeeding?

    PubMed

    Pistilli, Barbara; Bellettini, Giulia; Giovannetti, Elisa; Codacci-Pisanelli, Giovanni; Azim, Hatem A; Benedetti, Giovanni; Sarno, Maria Anna; Peccatori, Fedro A

    2013-05-01

    An increasing number of women are diagnosed with cancer during pregnancy and lactation. Women are usually advised to interrupt breastfeeding during systemic anticancer treatment for fear of serious adverse effects to the nursed infant. However, the issue is poorly addressed in the literature and very few studies have evaluated the safety of breastfeeding during or after cytotoxic drugs or target agents administration. In this review we will analyze the available evidence that addresses the issue of anticancer drugs, targeted agents, antiemetics and growth-factors excretion in human milk. This could serve as a unique resource that may aid physicians in the management of breastfeeding cancer patients interested in maintaining lactation during treatment. PMID:23199900

  17. What psychosocial factors influence adolescents' oral health?

    PubMed

    Baker, S R; Mat, A; Robinson, P G

    2010-11-01

    Few studies have examined, comprehensively and prospectively, determinants of oral-health-related quality of life. The aim of this study was to examine the relationships between psychosocial factors and oral health status, health perceptions, and quality of life. Measures of symptom and functional status, health perceptions, quality of life, oral health beliefs, and psychological (sense of coherence, self-esteem, health locus of control) and social factors (parents' income and education) were collected from 439 12- and 13-year-olds at baseline and six-month follow-up, together with a clinical examination at baseline. Structural equation modeling indicated that increased levels of caries and more symptoms predicted more functional limitations, and, cross-sectionally, greater functional impact was associated with worse health perceptions, which were linked to lower quality of life. Sense of coherence was the most important psychosocial predictor. These factors are important in understanding how oral health affects young people's daily lives. PMID:20739689

  18. Intake of milk, but not total dairy, yogurt, or cheese, is negatively associated with the clustering of cardiometabolic risk factors in adolescents.

    PubMed

    Abreu, Sandra; Moreira, Pedro; Moreira, Carla; Mota, Jorge; Moreira-Silva, Isabel; Santos, Paula-Clara; Santos, Rute

    2014-01-01

    Epidemiologic studies have reported an inverse association between dairy product consumption and cardiometabolic risk factors in adults, but this relation is relatively unexplored in adolescents. We hypothesized that a higher dairy product intake is associated with lower cardiometabolic risk factor clustering in adolescents. To test this hypothesis, a cross-sectional study was conducted with 494 adolescents aged 15 to 18 years from the Azorean Archipelago, Portugal. We measured fasting glucose, insulin, total cholesterol, high-density lipoprotein cholesterol, triglycerides, systolic blood pressure, body fat, and cardiorespiratory fitness. We also calculated homeostatic model assessment and total cholesterol/high-density lipoprotein cholesterol ratio. For each one of these variables, a z score was computed using age and sex. A cardiometabolic risk score (CMRS) was constructed by summing up the z scores of all individual risk factors. High risk was considered to exist when an individual had at least 1 SD from this score. Diet was evaluated using a food frequency questionnaire, and the intake of total dairy (included milk, yogurt, and cheese), milk, yogurt, and cheese was categorized as low (equal to or below the median of the total sample) or "appropriate" (above the median of the total sample).The association between dairy product intake and CMRS was evaluated using separate logistic regression, and the results were adjusted for confounders. Adolescents with high milk intake had lower CMRS, compared with those with low intake (10.6% vs 18.1%, P = .018). Adolescents with appropriate milk intake were less likely to have high CMRS than those with low milk intake (odds ratio, 0.531; 95% confidence interval, 0.302-0.931). No association was found between CMRS and total dairy, yogurt, and cheese intake. Only milk intake seems to be inversely related to CMRS in adolescents. PMID:24418246

  19. Factors Influencing Recruitment in Educational Psychology

    ERIC Educational Resources Information Center

    Frederickson, Norah

    2003-01-01

    This paper reports an investigation of the factors that educational psychologists in training (EPiTs) look for when applying for jobs in educational psychology services. Relevant literature on "job attraction" is reviewed and a three-stage research process employed. This involved a focus group approach to questionnaire generation followed by…

  20. The Influence of Noneconomic Factors on Negotiators

    ERIC Educational Resources Information Center

    Tracy, Lane

    1974-01-01

    Certain noneconomic factors in collective bargaining are directly related to the negotiator's personal inclination to settle for the new contract. In this study, the pattern of relationships between the parties, the nature of the work itself, favorable recognition, team policy, and interpersonal relationships proved to be significantly related to…

  1. Factors Influencing the Elimination of Dietary Restraint.

    ERIC Educational Resources Information Center

    Herman, C. Peter; Polivy, Janet

    Recent research by Herman, Polivy, and their colleagues has been concerned with the determinants of self-control and disinhibition in dieters. The present paper summarizes a number of studies in which the reactions of dieters and nondieters to a variety of disinhibitory factors (preloading, emotional arousal, intoxication) were investigated. The…

  2. Factors Influencing uUniversity Research Performance

    ERIC Educational Resources Information Center

    Edgar, Fiona; Geare, Alan

    2013-01-01

    This research extends our understanding of research productivity by examining features of managerial practice and culture within university departments. Adopting a robust comparative research design, capturing both interview and survey data sourced from multiple stakeholders from New Zealand universities, we seek to identify factors associated…

  3. Environmental factors influencing growth and pubertal development.

    PubMed Central

    Delemarre-van de Waal, H A

    1993-01-01

    Postnatal growth is based on hereditary signals and environmental factors in a complex regulatory network. Each factor must be in an optimal state for normal growth of the child. Fetal conditions may also have consequences on postnatal height. Intrauterine growth retardation can be recovered postnatally, although postnatal growth remains depressed in about one-third of cases. After birth, the environment may exert either a positive or negative effect on growth. In underdeveloped countries, malnutrition plays a major role in inhibiting the growth process. Children from families of higher socioeconomic classes are taller than their coevals in the lower socioeconomic groups. Urbanization also has a positive effect on growth. Better child care is supported by sufficient food supply, appropriate health and sanitation services, and a higher level of education. Over the last century, these factors have induced a taller stature and a more rapid maturity in Europe, North America, and Australia; a phenomenon which has been referred to as "the secular trend" in growth. Recently, a secular trend has also been reported in some developing countries. Although urbanization in general appears to be associated with better conditions of living, this is not the case in the slums of South America or in Africa where rural children are better off than children living in the poor cities. This paper describes in more detail the different hereditary and environmental factors that act during the fetal period and postnatally, and which play a role in human growth and pubertal development. PMID:8243404

  4. The influence of casein haplotype on quality, coagulation, and yield traits of milk from Italian Holstein cows.

    PubMed

    Perna, Annamaria; Intaglietta, Immacolata; Gambacorta, Emilio; Simonetti, Amalia

    2016-05-01

    The aim of this work was to investigate the effect of casein haplotype (CSN1S1, CSN2, and CSN3) on quality, coagulation, and yield traits of milk from Italian Holstein cows. The casein haplotype was determined by isoelectric focusing; milk clotting properties were determined by using a mechanical lacto-dynamographic instrument; and the yields of pressed and pasta filata cheeses were expressed as kilograms of cheese per 100kg of milk processed. Statistical analysis showed a significant effect of the casein haplotype. In particular, BB-A(1)A(1)-AA milk showed the highest fat content (4.01g/100g), whereas BB-A(2)A(2)-BB milk had a higher protein content, the best coagulation characteristics, and the highest yields in pressed and pasta filata cheeses, and, consequently, better ability to retain fat and protein in the curd. The results of this study suggest that knowledge of milk protein polymorphisms not only allows the production of milk with specific qualitative and quantitative characteristics, but it could also be used as a specific marker within a breed to identify milk suitable for cheesemaking, which confers an economical advantage for dairy producers. PMID:26947288

  5. OVEREXPRESSION OF DES(1-3) INSULIN-LIKE GROWTH FACTOR 1 IN THE MAMMARY GLANDS OF TRANSGENIC MICE DELAYS THE LOSS OF MILK PRODUCTION WITH PROLONGED LACTATION

    Technology Transfer Automated Retrieval System (TEKTRAN)

    During prolonged lactation, the mammary gland gradually loses the capacity to produce milk. In agricultural species, this decline can be slowed by administration of exogenous growth hormone (GH), which is believed to act through insulin-like growth factor 1 (IGF1). Our previous work demonstrated del...

  6. Fat source and dietary forage-to-concentrate ratio influences milk fatty-acid composition in lactating cows.

    PubMed

    Vazirigohar, M; Dehghan-Banadaky, M; Rezayazdi, K; Krizsan, S J; Nejati-Javaremi, A; Shingfield, K J

    2014-01-01

    On the basis of the potential benefits to human health there is an increased interest in producing milk containing lower-saturated fatty acid (SFA) and higher unsaturated fatty acid (FA) concentrations, including cis-9 18:1 and cis-9, trans-11-conjugated linoleic acid (CLA). Twenty-four multiparous Holstein cows were used in two experiments according to a completely randomized block design, with 21-day periods to examine the effects of incremental replacement of prilled palm fat (PALM) with sunflower oil (SFO) in high-concentrate diets containing 30 g/kg dry matter (DM) of supplemental fat (Experiment 1) or increases in the forage-to-concentrate (F : C) ratio from 39 : 61 to 48 : 52 of diets containing 30 g/kg DM of SFO (Experiment 2) on milk production, digestibility and milk FA composition. Replacing PALM with SFO had no effect on DM intake, but tended to increase organic matter digestibility, yields of milk, protein and lactose, and decreased linearly milk fat content. Substituting SFO for PALM decreased linearly milk fat 8:0 to 16:0 and cis-9 16:1, and increased linearly 18:0, cis-9 18:1, trans-18:1 (��4 to 16), 18:2 and CLA concentrations. Increases in the F : C ratio of diets containing SFO had no effect on intake, yields of milk, milk protein or milk lactose, lowered milk protein content in a quadratic manner, and increased linearly NDF digestion and milk fat secretion. Replacing concentrates with forages in diets containing SFO increased milk fat 4:0 to 10:0 concentrations in a linear or quadratic manner, decreased linearly cis-9 16:1, trans-6 to -10 18:1, 18:2n-6, trans-7, cis-9 CLA, trans-9, cis-11 CLA and trans-10, cis-12 CLA, without altering milk fat 14:0 to 16:0, trans-11 18:1, cis-9, trans-11 CLA or 18:3n-3 concentrations. In conclusion, replacing prilled palm fat on with SFO in high-concentrate diets had no adverse effects on intake or milk production, other than decreasing milk fat content, but lowered milk fat medium-chain SFA and increased

  7. Influence of Sunflower Whole Seeds or Oil on Ruminal Fermentation, Milk Production, Composition, and Fatty Acid Profile in Lactating Goats.

    PubMed

    Morsy, T A; Kholif, S M; Kholif, A E; Matloup, O H; Salem, A Z M; Elella, A Abu

    2015-08-01

    This study aimed to investigate the effect of sunflower seeds, either as whole or as oil, on rumen fermentation, milk production, milk composition and fatty acids profile in dairy goats. Fifteen lactating Damascus goats were divided randomly into three groups (n = 5) fed a basal diet of concentrate feed mixture and fresh Trifolium alexandrinum at 50:50 on dry matter basis (Control) in addition to 50 g/head/d sunflower seeds whole (SS) or 20 mL/head/d sunflower seeds oil (SO) in a complete randomized design. Milk was sampled every two weeks during 90 days of experimental period for chemical analysis and rumen was sampled at 30, 60, and 90 days of the experiment for ruminal pH, volatile fatty acids (tVFA), and ammonia-N determination. Addition of SO decreased (p = 0.017) ruminal pH, whereas SO and SS increased tVFA (p<0.001) and acetate (p = 0.034) concentrations. Serum glucose increased (p = 0.013) in SO and SS goats vs Control. The SO and SS treated goats had improved milk yield (p = 0.007) and milk fat content (p = 0.002). Moreover, SO increased milk lactose content (p = 0.048) and feed efficiency (p = 0.046) compared to Control. Both of SS and SO increased (p<0.05) milk unsaturated fatty acids content specially conjugated linolenic acid (CLA) vs Control. Addition of SS and SO increased (p = 0. 021) C18:3N3 fatty acid compared to Control diet. Data suggested that addition of either SS or SO to lactating goats ration had beneficial effects on milk yield and milk composition with enhancing milk content of healthy fatty acids (CLA and omega 3), without detrimental effects on animal performance. PMID:26104519

  8. Influence of Sunflower Whole Seeds or Oil on Ruminal Fermentation, Milk Production, Composition, and Fatty Acid Profile in Lactating Goats

    PubMed Central

    Morsy, T. A.; Kholif, S. M.; Kholif, A. E.; Matloup, O. H.; Salem, A. Z. M.; Elella, A. Abu

    2015-01-01

    This study aimed to investigate the effect of sunflower seeds, either as whole or as oil, on rumen fermentation, milk production, milk composition and fatty acids profile in dairy goats. Fifteen lactating Damascus goats were divided randomly into three groups (n = 5) fed a basal diet of concentrate feed mixture and fresh Trifolium alexandrinum at 50:50 on dry matter basis (Control) in addition to 50 g/head/d sunflower seeds whole (SS) or 20 mL/head/d sunflower seeds oil (SO) in a complete randomized design. Milk was sampled every two weeks during 90 days of experimental period for chemical analysis and rumen was sampled at 30, 60, and 90 days of the experiment for ruminal pH, volatile fatty acids (tVFA), and ammonia-N determination. Addition of SO decreased (p = 0.017) ruminal pH, whereas SO and SS increased tVFA (p<0.001) and acetate (p = 0.034) concentrations. Serum glucose increased (p = 0.013) in SO and SS goats vs Control. The SO and SS treated goats had improved milk yield (p = 0.007) and milk fat content (p = 0.002). Moreover, SO increased milk lactose content (p = 0.048) and feed efficiency (p = 0.046) compared to Control. Both of SS and SO increased (p<0.05) milk unsaturated fatty acids content specially conjugated linolenic acid (CLA) vs Control. Addition of SS and SO increased (p = 0. 021) C18:3N3 fatty acid compared to Control diet. Data suggested that addition of either SS or SO to lactating goats ration had beneficial effects on milk yield and milk composition with enhancing milk content of healthy fatty acids (CLA and omega 3), without detrimental effects on animal performance. PMID:26104519

  9. Interleukin 10 (IL10) and transforming growth factor β1 (TGFβ1) gene polymorphisms in persistent IgE-mediated cow's milk allergy

    PubMed Central

    Jacob, Cristina Miuki Abe; Pastorino, Antonio Carlos; Okay, Thelma Suely; Castro, Ana Paula BM; Gushken, Andrea Keiko F.; Watanabe, Letícia Aki; Frucchi, Vanessa CZ; de Oliveira, Léa Campos

    2013-01-01

    OBJECTIVES: The aim of this cross-sectional study was to evaluate whether interleukin 10 (IL10) and transforming growth factor β1 (TGFβ1) gene polymorphisms were associated with persistent IgE-mediated cow's milk allergy in 50 Brazilian children. The diagnostic criteria were anaphylaxis triggered by cow's milk or a positive double-blind, placebo-controlled food challenge. Tolerance was defined as the absence of a clinical response to a double-blind, placebo-controlled food challenge or cow's milk exposure. METHOD: The genomic DNA of the 50 patients and 224 healthy controls (HCs) was used to investigate five IL10 gene polymorphisms (-3575A/T, -2849A/G, -2763A/C, -1082G/A, -592C/A) and one TGFβ1 polymorphism (-509C/T). RESULTS: Among the five IL10 polymorphisms analyzed, homozygosis for the G allele at the -1082 position was significantly higher in the patients compared with the healthy controls (p = 0.027) and in the persistent cow's milk allergy group compared with the healthy controls (p = 0.001). CONCLUSIONS: Homozygosis for the G allele at the IL10 -1082G/A polymorphism is associated with the persistent form of cow's milk allergy. PMID:23917667

  10. Estimating efficiency in automatic milking systems.

    PubMed

    Castro, A; Pereira, J M; Amiama, C; Bueno, J

    2012-02-01

    Milking data of 34 single automatic milking system (AMS) units on 29 Galician dairy farms were analyzed to determine the system capacity in each farm under actual working conditions. Number of cows, milk yield, milkings per cow per day, actual milking time, rejected milking time, cleaning time, and machine downtime were used to determine the number of cows milked per AMS unit to obtain the optimal values of milkings per cow and milk production. Multiple linear regression data analysis was used to model the linear relationship between the dependent variable, milk yield per AMS per year, and the predictor variables: number of cows per AMS, milkings per cow per day, milk flow rate, and rejections per AMS per year. An AMS unit milked 52.7±9.0 cows daily at 2.69±0.28 milkings per cow, with a total milking downtime of 1,947±978 h/yr and a milk yield of 549,734±126,432 kg/yr. The predictor variables cow and milk flow rate had a greater level of influence on the milk yield per AMS than milkings per cow and rejections, and explained the 87% of the variation. The AMS in Galician dairy farms could facilitate an increase of 16±8.5 cows per AMS without impairing milking performance; in this way, the quantity of milk obtained per robot annually could be increased (185,460±137,460 kg). This would make it possible to recoup the cost of the system earlier. In the present situation, the daily milking throughput could be maximized at 2.4 to 2.6 milkings per cow. PMID:22281358

  11. Factors influencing the intensity of magnetospheric substorms

    NASA Technical Reports Server (NTRS)

    Mcpherron, R. L.; Baker, D. N.

    1993-01-01

    A definition of the substorm is presented, and it is shown that the typical isolated substorm is produced by the superposition of effects of processes directly driven by the solar wind through dayside reconnection and those driven by unloading through nighttime reconnection. The single factor that determines whether a substorm will occur or not is the clock angle of the interplanetary magnetic field (IMF) around the earth-sun line. Only when this field points south of the GSM equatorial plane do the auroral electrojet indices depart from their quiet values. For a given clock angle, the level of activity increases with the IMF strength and solar wind velocity.

  12. Factors Influencing Childhood Immunization in Uganda

    PubMed Central

    2013-01-01

    This paper investigates the factors associated with childhood immunization in Uganda. We used nationally-representative data from Uganda Demographic and Health Survey (UDHS) of 2006. Both bivariate and multivariate approaches were employed in the analysis. The bivariate approach involved generating average percentages of children who were immunized, with analysis of pertinent background characteristics. The multivariate approach involved employing maximum likelihood probit technique and generating marginal effects to ascertain the probability of being immunized, given the same background characteristics. It revealed that slightly over 50% of children in Uganda were fully immunized. Additionally, 89%, 24%, 52%, and 64% received BCG, DPT, polio and measles vaccines respectively. Factors which have a significant association with childhood immunization are: maternal education (especially at post-secondary level), exposure to media, maternal healthcare utilization, maternal age, occupation type, immunization plan, and regional and local peculiarities. Children whose mothers had post-secondary education were twice as likely to be fully immunized compared to their counterparts whose mothers had only primary education (p<0.01). Thus, gender parity in education enhancement efforts is crucial. There is also a need to increase media penetration, maternal healthcare utilization, and to ensure parity across localities and regions. PMID:23617212

  13. Factors influencing the spinal motoneurons in development

    PubMed Central

    Wiese, Stefan

    2015-01-01

    The development of the spinal cord needs a concerted interaction of transcription factors activating diverse genes and signals from outside acting on the specification of the different cells. Signals have to act on the segments of the embryo as well as on the cranial-caudal axis and the dorso-ventral axis. Additionally the axons of the motoneurons have to cross the central nervous system barrier to connect to the periphery. Intensive anatomical studies have been followed by molecular characterization of the different subsets of transcription factors that are expressed by cells of the developing spinal cord. Here, intensive studies for the most important appearing cells, the motoneurons, have resulted in a good knowledge on the expression patterns of these proteins. Nonetheless motoneurons are by far not the only important cells and the concert activity of all cells besides them is necessary for the correct function and integrity of motoneurons within the spinal cord. This article will briefly summarize the different aspects on spinal cord development and focuses on the differentiation as well as the functionalization of motoneurons. PMID:26807112

  14. Factors influencing childhood immunization in Uganda.

    PubMed

    Bbaale, Edward

    2013-03-01

    This paper investigates the factors associated with childhood immunization in Uganda. We used nationally-representative data from Uganda Demographic and Health Survey (UDHS) of 2006. Both bivariate and multivariate approaches were employed in the analysis. The bivariate approach involved generating average percentages of children who were immunized, with analysis of pertinent background characteristics. The multivariate approach involved employing maximum likelihood probit technique and generating marginal effects to ascertain the probability of being immunized, given the same background characteristics. It revealed that slightly over 50% of children in Uganda were fully immunized. Additionally, 89%, 24%, 52%, and 64% received BCG, DPT, polio and measles vaccines respectively. Factors which have a significant association with childhood immunization are: maternal education (especially at post-secondary level), exposure to media, maternal healthcare utilization, maternal age, occupation type, immunization plan, and regional and local peculiarities. Children whose mothers had post-secondary education were twice as likely to be fully immunized compared to their counterparts whose mothers had only primary education (p < 0.01). Thus, gender parity in education enhancement efforts is crucial. There is also a need to increase media penetration, maternal healthcare utilization, and to ensure parity across localities and regions. PMID:23617212

  15. Physicochemical behavior of oil-in-water emulsions: influence of milk protein mixtures, glycerol ester mixtures and fat characteristics.

    PubMed

    Granger, C; Barey, P; Veschambre, P; Cansell, M

    2005-05-25

    Different emulsions based on two protein mixtures (skim milk powder (SMP) and functional dairy proteins (FDP)), two mono-di-glyceride mixtures (MDG) (saturated and partially unsaturated), three fats (hydrogenated and refined coconut oils and refined palm oil) were studied to investigate the interactions occurring between the oil phase, low molecular weight emulsifiers and proteins. Immediately following the emulsification process, high diameters of fat globules were obtained in FDP-based systems, relevant of an aggregation phenomenon. At this stage, the fat globule size characteristics were dependent on the emulsifier and fat types present in the formulation. In contrast, SMP-based emulsions were characterized by low proportions of aggregated particles regardless the formulations. Ageing (24 h at 4 degrees C) promoted disaggregation in FDP formulations, while SMP emulsions were well stabilized. Just after the homogenization step, less proteins were required to stabilize the globule interface in FDP systems as compared to SMP ones. Only with SMP, the amount of protein load at the fat globule surface was influenced by the oil nature and/or by the emulsifier type. A competitive adsorption of caseins, over whey proteins, was demonstrated in the case of FDP. The ageing period promoted a displacement of the proteins adsorbed at the oil droplet interface, suggesting a disruption of the interfacial protein interactions. This disruption was more marked with SMP than with FDP and, in both cases, was more or less influenced by the emulsifier and oil phase natures. The variations of the viscosity and rheological parameters (elastic and viscous moduli) were not dependent on one specific component of the formulation. PMID:15893224

  16. Factors influencing whether children walk to school.

    PubMed

    Su, Jason G; Jerrett, Michael; McConnell, Rob; Berhane, Kiros; Dunton, Genevieve; Shankardass, Ketan; Reynolds, Kim; Chang, Roger; Wolch, Jennifer

    2013-07-01

    Few studies have simultaneously evaluated multiple levels of influence on whether children walk to school. A large cohort of 4338 subjects from 10 communities was used to identify the determinants of walking through (1) a one-level logistic regression model for individual-level variables and (2) a two-level mixed regression model for individual and school-level variables. Walking rates were positively associated with home-to-school proximity, greater age, and living in neighborhoods characterized by lower traffic density. Greater land use mix around the home was, however, associated with lower rates of walking. Rates of walking to school were also higher amongst recipients of the Free and Reduced Price Meals Program and attendees of schools with higher percentage of English language learners. Designing schools in the same neighborhood as residential districts should be an essential urban planning strategy to reduce walking distance to school. Policy interventions are needed to encourage children from higher socioeconomic status families to participate in active travel to school and to develop walking infrastructures and other measures that protect disadvantaged children. PMID:23707968

  17. Factors Influencing Whether Children Walk to School

    PubMed Central

    Su, Jason G.; Jerrett, Michael; Mcconnell, Rob; Berhane, Kiros; Dunton, Genevieve; Shankardass, Ketan; Reynolds, Kim; Chang, Roger; Wolch, Jennifer

    2015-01-01

    Few studies have evaluated multiple levels of influence simultaneously on whether children walk to school. A large cohort of 4,338 subjects from ten communities was used to identify the determinants of walking through (1) a one-level logistic regression model for individual-level variables and (2) a two-level mixed regression model for individual and school-level variables. Walking rates were positively associated with home-to-school proximity, greater age, and living in neighborhoods characterized by lower traffic density. Greater land use mix around the home was, however, associated with lower rates of walking. Rates of walking to school were also higher amongst recipients of the Free and Reduced Price Meals Program and attendees of schools with higher percentage of English language learners. Designing schools in the same neighborhood as residential districts should be an essential urban planning strategy to reduce walking distance to school. Policy interventions are needed to encourage children from higher socioeconomic status families to participate in active travel to school and to develop walking infrastructures and other measures that protect disadvantaged children. PMID:23707968

  18. Short communication: Factors affecting vitamin B12 concentration in milk of commercial dairy herds: An exploratory study.

    PubMed

    Duplessis, M; Pellerin, D; Cue, R I; Girard, C L

    2016-06-01

    Only bacteria can synthesize vitamin B12, and this requires adequate Co supply. The natural source of vitamin B12 in human diets comes from animal products, especially those from ruminants. This study aimed to describe variability regarding vitamin B12 concentration in milk among and within commercial dairy herds in early lactation. A secondary objective was to explore potential causes for this variability such as genetic variation and diet characteristics. In total, 399 dairy cows (135 primiparous and 264 multiparous; 386 Holstein and 13 Jersey cows) in 15 commercial herds were involved. Milk samples were taken at 27.4±4.1 and 55.4±4.1d in milk. Neither parity (primiparous vs. multiparous) nor sampling time affected milk concentrations of vitamin B12. Nevertheless, vitamin B12 concentration in milk was highly variable among and within dairy herds. The lowest vitamin B12 concentration in milk of cows was observed in the Jersey herd. Among herds, vitamin B12 concentration in milk ranged from 2,309 to 3,878 pg/mL; one glass (250mL) of milk from those herds would provide between 23 and 40% of the vitamin B12 recommended daily allowance. Among individual cows, however, this provision varied between 16 and 57% of the recommendation. In spite of the limited size of the studied population, the heritability value was 0.23, suggesting that genetic selection could modify milk vitamin B12 concentration. We observed a positive relationship between milk vitamin B12 concentration and dietary acid detergent fiber content and a negative relationship between milk concentration of vitamin B12 and dietary crude protein content. PMID:27040783

  19. Short communication: Associations between teat dimensions and milking-induced changes in teat dimensions and quarter milk somatic cell counts in dairy cows.

    PubMed

    Zwertvaegher, I; De Vliegher, S; Verbist, B; Van Nuffel, A; Baert, J; Van Weyenberg, S

    2013-02-01

    Although many studies have examined the relation between a wide range of factors and quarter milk somatic cell count (qSCC), including physical characteristics of the teat and changes in teat tissue due to milking, the effect of short-term, milking-induced changes in teat dimensions on somatic cell count has not yet been investigated. To identify teat dimensions and milking-induced changes in teat dimensions associated with qSCC, we conducted a longitudinal study (n(herds)=6, n(cows)=72, n(measurements)=12). Parity, stage of lactation, teat barrel diameter, and changes in teat barrel diameter during milking were identified as factors associated with qSCC. Teats with wider barrels had higher qSCC. Negative changes in the diameter of the teat barrel during milking (i.e., thinner teats postmilking compared with premilking) were associated with lower qSCC, whereas positive changes (i.e., thicker teats postmilking compared with premilking) were associated with higher qSCC. Selection toward more optimal teat characteristics may therefore result in improved milk quality and udder health. However, a threshold might exist for the maximum reduction in teat barrel diameter below which udder health is negatively influenced. If so, changes in teat barrel diameter might serve as an indicator for suboptimal milking and incorrect choice of teatcup liner or milking machine settings and thus help improve management of the herd. PMID:23219124

  20. Studies on soil to grass transfer factor (Fv) and grass to milk transfer coefficient (Fm) for cesium in Kaiga region.

    PubMed

    Karunakara, N; Ujwal, P; Yashodhara, I; Rao, Chetan; Sudeep Kumara, K; Dileep, B N; Ravi, P M

    2013-10-01

    Detailed studies were carried out to establish site-specific soil to grass transfer factors (Fv) and grass to cow milk transfer coefficients (Fm) for radioactive cesium ((137)Cs) and stable cesium (Cs) for Kaiga region, where a nuclear power station has been in operation for more than 10 years. The study included adopted cows, cows of local farmers, and cows from the dairy farm. A grass field was developed specifically for the study and 2 local breed cows were adopted and allowed to graze in this grass field. The soil and grass samples were collected regularly from this field and analyzed for the concentrations of (137)Cs and stable Cs to evaluate the soil to grass Fv values. The milk samples from the adopted cows were analyzed for the (137)Cs and stable Cs concentrations to evaluate Fm values. For comparison, studies were also carried out in dominant grazing areas in different villages around the nuclear power plant and the cows of local farmers which graze in these areas were identified and milk samples were collected and analyzed regularly. The geometric mean values of Fv were found to be 1.1 × 10(-1) and 1.8 × 10(-1) for (137)Cs and stable Cs, respectively. The Fm of (137)Cs had geometric mean values of 1.9 × 10(-2) d L(-1) and 4.6 × 10(-2) d L(-1), respectively, for adopted Cows 1 and 2; 1.7 × 10(-2) d L(-1) for the cows of local farmers, and 4.0 × 10(-3) d L(-1) for the dairy farm cows. The geometric mean values of Fm for stable Cs were similar to those of (137)Cs. The Fm value for the dairy farm cows was an order of magnitude lower than those for local breed cows. The Fm values observed for the local breed cows were also an order of magnitude higher when compared to the many values reported in the literature and in the IAEA publication. Possible reasons for this higher Fm values were identified. The correlation between Fv and Fm values for (137)Cs and stable Cs and their dependence on the potassium content ((40)K and stable K) in

  1. Factors influencing riverine fish assemblages in Massachusetts

    USGS Publications Warehouse

    Armstrong, David S.; Richards, Todd A.; Levin, Sara B.

    2011-01-01

    The U.S. Geological Survey, in cooperation with the Massachusetts Department of Conservation and Recreation, Massachusetts Department of Environmental Protection, and the Massachusetts Department of Fish and Game, conducted an investigation of fish assemblages in small- to medium-sized Massachusetts streams. The objective of this study was to determine relations between fish-assemblage characteristics and anthropogenic factors, including impervious cover and estimated flow alteration, relative to the effects of environmental factors, including physical-basin characteristics and land use. The results of this investigation supersede those of a preliminary analysis published in 2010. Fish data were obtained for 669 fish-sampling sites from the Massachusetts Division of Fisheries and Wildlife fish-community database. A review of the literature was used to select fish metrics - species richness, abundance of individual species, and abundances of species grouped on life history traits - responsive to flow alteration. The contributing areas to the fish-sampling sites were delineated and used with a geographic information system to determine a set of environmental and anthropogenic factors that were tested for use as explanatory variables in regression models. Reported and estimated withdrawals and return flows were used together with simulated unaltered streamflows to estimate altered streamflows and indicators of flow alteration for each fish-sampling site. Altered streamflows and indicators of flow alteration were calculated on the basis of methods developed in a previous U.S. Geological Survey study in which unaltered daily streamflows were simulated for a 44-year period (water years 1961-2004), and streamflow alterations were estimated by use of water-withdrawal and wastewater-return data previously reported to the State for the 2000-04 period and estimated domestic-well withdrawals and septic-system discharges. A variable selection process, conducted using principal

  2. Factors influencing phototaxis in nocturnal migrating birds.

    PubMed

    Zhao, Xuebing; Chen, Mingyan; Wu, Zhaolu; Wang, Zijiang

    2014-12-01

    Many migratory bird species fly during the night (nocturnal migrants) and have been shown to display some phototaxis to artificial light. During 2006 to 2009, we investigated phototaxis in nocturnal migrants at Jinshan Yakou in Xinping County (N23°56', E101°30'; 2400 m above sea-level), and at the Niaowang Mountain in Funing County (N23°30', E105°35'; 1400 m above sea-level), both in the Yunnan Province of Southwest China. A total of 5069 birds, representing 129 species, were captured by mist-netting and artificial light. The extent of phototaxis effect on bird migration was examined during all four seasons, three phases of the moon, and under two weather conditions (mist and wind). Data were statistically analyzed to determine the extent to which these factors may impact phototaxis of nocturnal migrants. The results point to phototaxis in birds migrating in the spring and autumn, especially in the autumn. Furthermore, migrating birds were more readily attracted to artificial lights during nights with little moonlight, mist, and a headwind. Regardless of the initial orientation in which birds flew, either following the wind or against the wind, birds would always fly against the wind when flying towards the light. This study broadens our understanding of the nocturnal bird migration, potentially resulting in improved bird ringing practices, increased awareness, and better policies regarding bird protection. PMID:25483789

  3. Factors influencing single mother's employment status.

    PubMed

    Youngblut, J M; Brady, N R; Brooten, D; Thomas, D J

    2000-03-01

    Changes in the welfare system limit the length of time a person can receive welfare benefits, thus mandating employment for many current welfare recipients. Single mothers with young children who do not become employed will lose financial support for housing, food, clothing, and health care and place their own and their children's health and safety at risk. The purpose of this qualitative study was to explore women's experiences of being unemployed and to examine the barriers to employment perceived by single mothers who expressed a desire to be employed. Nine mothers were recruited from a larger sample of single mothers who had participated in a quantitative study about employment conducted 1 to 2 years earlier. Using focus group interviews, mothers were asked what it was like to be a single mother, and then what barriers to their employment they perceived. Two dimensions were identified from the mothers' statements. The first, a sense of obligation, included themes of "being there" for their own and their child's benefit and doing what it takes to optimize the child's growth and development. The second, negotiating the obstacles, referred to problems regarding child care, lack of involvement of the child's father and lack of support from relatives and friends for the mother's efforts toward securing employment. These findings have important implications for welfare reform, namely, that efforts aimed at moving nonemployed single mothers into the workforce will fail if these factors are not considered. PMID:10818834

  4. Breast cancer diagnosis and factors influencing treatment decisions in Ghana.

    PubMed

    Aziato, Lydia; Clegg-Lamptey, Joe Nat A

    2015-01-01

    Researchers in this study explored the reactions of women with breast cancer and identified factors influencing treatment decisions. A qualitative exploratory approach was employed. Participants were recruited from a tertiary hospital and a breast cancer support group. Purposive sampling recruited 12 women. It was found that women identified breast lesions accidentally or intentionally and that diagnosis was delayed. Emotional reactions to diagnosis included shock and sadness. Factors that influenced treatment were the influence of other people, alternative sources of treatment, faith and support, knowledge, "tuning the mind," and effects on intimacy. Health professionals should develop effective communication and counseling skills for clients. PMID:24750095

  5. Moose milk and hair element levels and relationships.

    PubMed

    Franzmann, A W; Flynn, A; Arneson, P D

    1976-04-01

    Milk was collected from 21 Alaskan moose (Alces alces gigas) at the Kenai Moose Research Center (MRC), Soldotna, Alaska nad analyzed by atomic absorption spectroscopy for Al, As, Ca, Cd, Co, Cr, Cu, Fe, Hg, K, Mg, Mn, Mo, Na, Ni, Pb, Se and Zn. Hair samples were collected from 100 moose at the MRC to correspond with the lactation period and serve as a metabolic indicator of mineral elements stored in tissue. Published analyses of bovine milk were compared to moose milk; Al, Fe, Se and Zn were higher in moose milk by factors of 1.6 to 290. Elements potentially influenced by nutrition and those determined genetically were also considered. Elements in moose milk and hair values were compared, since mineral element levels in hair potentially reflect the availability and intake of these elements. Calcium and Mg were the only values in hair lower than the values in milk (factors of 4.2 and 1.5 respectively). Moose, as well as domestic cattle, apparently are subjected to lactation stress by the genetically determined levels of Ca and Mg in milk. PMID:933310

  6. Depression Following Hysterectomy and the Influencing Factors

    PubMed Central

    Bahri, Narjes; Tohidinik, Hamid Reza; Fathi Najafi, Tahereh; Larki, Mona; Amini, Thoraya; Askari Sartavosi, Zahra

    2016-01-01

    Background Hysterectomy is one of the most common gynecological surgeries performed worldwide. However, women undergoing this surgery often experience negative emotional reactions. Objectives This study was done with the aim of investigating the relationship between hysterectomy and postoperative depression, three months after the procedure. Materials and Methods This longitudinal study was conducted in the province of Khorasan-Razavi in Iran, using multistage sampling. At first, three cities were selected from the province by cluster sampling; then, five hospitals were randomly selected from these cities. The participants included 53 women who were hysterectomy candidates in one of the five selected hospitals. The participants’ demographics and hysterectomy procedure information were entered into two separate questionnaires, and the Beck depression inventory (BDI) was employed to measure their severity of depression before and three months after the surgery. The statistical package for the social sciences (SPSS) version 16 was used for the statistical analysis, and a P value of < 0.05 was considered to be statistically significant. Results The means and standard deviations of the participants’ depression scores before and three months after their hysterectomies were 13.01 ± 10.1 and 11.02 ± 10.3, respectively. Although the mean score of depression decreased three months after the hysterectomy, the difference was not statistically significant. However, a significant relationship was found between the satisfaction with the outcome of the hysterectomy and the postoperative depression score (P = 0.04). Conclusions In this study, undergoing a hysterectomy did not show a relationship with postoperative depression three months after the surgery. Moreover, the only factor related to depression following a hysterectomy was satisfaction with the surgery. PMID:27066267

  7. Factors Influencing Students' Achievement in Form 5 Islamic Studies Subject

    ERIC Educational Resources Information Center

    bin Che Noh, Mohd Aderi; Omar, Noraini binti; bin Kasan, Hasnan

    2013-01-01

    This study is aimed at analyzing the factors influencing the achievements of students in the subject of Islamic Studies for Form 5 SPM (KBSM) in schools in the area of Samarahan, Sarawak. The factors analysed is attitude and interest. This is a survey based study and data was compiled from the survey forms which had the topic "Factors…

  8. Factors Influencing Pursuit of Higher Education: Validating a Questionnaire.

    ERIC Educational Resources Information Center

    Harris, Sandra M.

    This paper explains the process used to validate the construct validity of the Factors Influencing Pursuit of Higher Education Questionnaire. This questionnaire is a literature-based, researcher-developed instrument which gathers information on the factors thought to affect a person's decision to pursue higher education. The questionnaire includes…

  9. Factors influencing visits to school nurses by pregnant adolescents.

    PubMed

    Chen, S P; Telleen, S; Mitchell, D R; Chen, E H

    1992-01-01

    The influence of five factors on the first visit to school nurses by pregnant adolescents and adequacy of prenatal care was analyzed. Only one factor, age of baby's father, was found to be associated with adequacy of prenatal care. PMID:1518672

  10. From Hospital to Nursing Facility: Factors Influencing Decisions

    ERIC Educational Resources Information Center

    Mason, Susan E.; Auerbach, Charles; LaPorte, Heidi Heft

    2009-01-01

    This study addresses the factors influencing decisions to send medicine-surgical (med-surg) patients home or to nursing facilities (NFs). The sample (n = 7,852) was taken from a large, urban, teaching, med-surg unit where discharges were documented and data collected over a two-and-a-half-year period. Using logistical regression, the factors found…

  11. Factors Influencing International Students' Career Choice: A Comparative Study

    ERIC Educational Resources Information Center

    Singaravelu, Hemla D.; White, Lyle J.; Bringaze, Tammy B.

    2005-01-01

    This study examines the career development behavior of Asian international, non-Asian international, and domestic students, specifically the certainty of career and major choice and environmental factors that have influenced their choices. Environmental factors include family, school counselors, teacher, friends, and government. The results show…

  12. Alternative Administrative Certification: Socializing Factors Influencing Program Choice

    ERIC Educational Resources Information Center

    Bickmore, Dana L.; Bickmore, Steven T.; Raines, Sarah

    2013-01-01

    This study used an organizational socialization lens to examine factors influencing participants' decision to pursue the principalship and choice to engage in an alternate administration certification program. Through an analysis of participant focus groups and interviews, factors emerged from the codes that were compared with dimensions of…

  13. Factors Influencing Technology Planning in Developing Countries: A Literature Review

    ERIC Educational Resources Information Center

    Keengwe, Jared; Malapile, Sandy

    2014-01-01

    This article is a literature review concerning the factors that play an important role in the development of educational technology plans in the educational system of developing countries (DCs). Largely, the technology plans are influenced by factors that emanates from within the country (internal) and those outside of their borders (external).…

  14. Factors Influencing Digital Reference Triage: A Think-Aloud Study

    ERIC Educational Resources Information Center

    Pomerantz, Jeffrey

    2004-01-01

    This article describes a think-aloud study conducted to identify factors that influence the decisions made by digital reference "triagers" when performing triage on questions received by digital reference services. This study follows and expands on a Delphi study that identified factors that triagers agreed on after the fact of their performance…

  15. Factors Influencing Psychological Help Seeking in Adults: A Qualitative Study

    ERIC Educational Resources Information Center

    Topkaya, Nursel

    2015-01-01

    The aim of the current research is to identify which factors, and in what direction these factors influence adults' decisions to seek psychological help for their personal problems. The research was designed as a phenomenology model; the data was gathered through the semi-structured interview technique, which is mostly used in qualitative research…

  16. A Study of Factors Influencing Teacher Salaries in Vermont.

    ERIC Educational Resources Information Center

    Callas, Rosanne; McCormick, Rod

    A study was done of factors affecting differences in teacher salaries among Vermont towns. Data from 181 local education agencies were used for the study and a set of factors was examined that included family, community, and school information to determine what influences teacher salaries. Findings included the following: (1) average teacher's…

  17. Psychosocial Factors Influencing Competency of Children's Statements on Sexual Trauma

    ERIC Educational Resources Information Center

    Kim, Tae Kyung; Choi, Soul; Shin, Yee Jin

    2011-01-01

    Objectives: The objectives of this study are to assess children's competence to state their traumatic experience and to determine psychosocial factors influencing the competency of children's statements, such as emotional factors of children and parents and trauma-related variables, in Korean child sex abuse victims. Methods: We enrolled 214…

  18. Effect of some non-genetic factors on milk yield and composition of Draa indigenous goats under an intensive system of three kiddings in 2 years.

    PubMed

    Ibnelbachyr, Mustapha; Boujenane, Ismail; Chikhi, Abdelkader; Noutfia, Younes

    2015-04-01

    With 5 millions heads, goats occupy the second place after sheep in Morocco. The indigenous populations are generally raised for meat, except Draa goat that is raised as a dual purpose doe. The objective of this study was to assess milk yield and composition of Draa indigenous goat breed under an intensive system of three kiddings in 2 years and to evaluate the effects of non-genetic factors. Data were collected on 381 lactations between 2006 and 2012 and on 174 samples for milk composition between 2008 and 2010. The highest milk yield was recorded in does of 36-48 months old (84.3 ± 4.78), those suckling more than one kid (80.0 ± 3.39) and those kidding in spring (80.4 ± 3.60) and summer (79.9 ± 3.67). Except protein content, milk composition was not affected by age of does. Dry matter and fat content increased significantly with the lactation stage, protein content decreased from early to middle/late lactation, and lactose content was high in middle lactation. The highest dry matter and fat and lactose contents were obtained for summer kiddings, while the highest percent of protein was recorded for autumnal kiddings. It was concluded that under the three kiddings in 2-year system, Draa does produce enough milk with an interesting milk composition, indicating that this system may be used with success to improve farmers' income. PMID:25724925

  19. Factors influencing nursing career choices and choice of study program.

    PubMed

    Haron, Yafa; Reicher, Sima; Riba, Shoshana

    2014-01-01

    In advance of a recruitment campaign, Israeli first-year nursing students of all ethnicities were surveyed to elucidate what factors had influenced them to make nursing their career and what sort of training track they preferred. The responses made it clear that different factors influence different groups differently. There were noticeable differences by gender, age, and ethnicity. Overall, training institutions were chosen for their closeness to the student's home but other factors also operated among particular groups, such as institutional prestige and flexible entry criteria. There was a blatant preference for academic, particularly university-sited, programs over diploma programs. PMID:24878405

  20. Nurturing Sport Expertise: Factors Influencing the Development of Elite Athlete

    PubMed Central

    Baker, Joseph; Horton, Sean; Robertson-Wilson, Jennifer; Wall, Michael

    2003-01-01

    The development of expertise in sport is the result of successful interaction of biological, psychological, and sociological constraints. This review examines the training and environmental factors that influence the acquisition of sport expertise. Research examining the quality and quantity of training indicate that these two elements are crucial predictors of attainment. In addition, the possession of resources such as parental support and adequate coaching are essential. Social factors such as cultural influences and the relative age effect are also considered as determinants of sport expertise. Although it is evident that environmental factors are essential to the acquisition of high levels of sport development, further research is clearly required. PMID:24616603

  1. Influence of the emulsion droplet type on the rheological characteristics and microstructure of rennet gels from reconstituted milk.

    PubMed

    Gaygadzhiev, Zafir; Hill, Arthur; Corredig, Milena

    2009-08-01

    Rheological and microstructural properties of rennet-induced milk gels containing different fat globules were studied. Recombined milks were prepared by mixing reconstituted low-heat skim milk powder and anhydrous milk fat emulsified with reconstituted skim milk powder (SMP), sodium caseinate (NaCas), whey protein isolate (WPI) or Tween 20. Final elastic modulus of the rennet gels containing WPI- or Tween 20-stabilized fat globules showed significantly lower values compared with those prepared with SMP-emulsified fat globules. SMP-stabilized fat globules interacted with the continuous casein network reinforcing the gel structure. Confocal micrographs supported the rheological data revealing that gels containing SMP-stabilized fat globules formed a tighter network relative to other treatments. Microscopy images also showed some degree of droplet flocculation in the case of gels containing WPI- or Tween 20-stabilized fat globules, and this was most likely the cause of the increase of elastic modulus of these systems. Contrary to reports for acid-induced casein gels, NaCas-stabilized fat globules hindered the formation of rennet gels. These results illustrate that rennet gel structure is affected by droplet-droplet and droplet-casein interactions, which in turn are determined by the composition of the oil-water interface as well as the ionic equilibrium in the reconstituted milk gels. PMID:19519978

  2. Factors influencing adherence among older people with osteoarthritis.

    PubMed

    Loew, Laurianne; Brosseau, Lucie; Kenny, Glen P; Durand-Bush, Natalie; Poitras, Stéphane; De Angelis, Gino; Wells, George A

    2016-09-01

    This study aims to identify potential factors that could affect adherence and influence the implementation of an evidence-based structured walking program, among older adults diagnosed with knee osteoarthritis. A total of 69 participants with mild to moderate osteoarthritis of the knee fulfilled an online survey on potential factors that could affect their adherence to an evidence-based structured walking program. Adherence with regard to the influencing factors was explored using a logistic regression model. Results tend to show higher odds of adhering to the evidence-based walking program if the participants were supervised (more than 2.9 times as high), supported by family/friends (more than 3.7 times as high), and not influenced by emotional involvement (more than 11 times as high). The odds of adhering were 3.6 times lower for participants who indicated a change in their medication intake and 3.1 times lower for individuals who considered themselves as less physically active (95 % confidence interval (CI)). Our exploratory findings identified and defined potential adherence factors that could guide health professionals in their practice to better identify positive influences and obstacles to treatment adherence, which would lead to the adoption of a more patient-centered approach. A large-scale study is required to clearly delineate the key factors that would influence adherence. We addressed a new knowledge gap by identifying the main strategies to promote the long-term adherence of community-based walking program. PMID:26646111

  3. Critical factors and paths influencing construction workers' safety risk tolerances.

    PubMed

    Wang, Jiayuan; Zou, Patrick X W; Li, Penny P

    2016-08-01

    While workers' safety risk tolerances have been regarded as a main reason for their unsafe behaviors, little is known about why different people have different risk tolerances even when confronting the same situation. The aim of this research is to identify the critical factors and paths that influence workers' safety risk tolerance and to explore how they contribute to accident causal model from a system thinking perceptive. A number of methods were carried out to analyze the data collected through interviews and questionnaire surveys. In the first and second steps of the research, factor identification, factor ranking and factor analysis were carried out, and the results show that workers' safety risk tolerance can be influenced by four groups of factors, namely: (1) personal subjective perception; (2) work knowledge and experiences; (3) work characteristics; and (4) safety management. In the third step of the research, hypothetical influencing path model was developed and tested by using structural equation modeling (SEM). It is found that the effects of external factors (safety management and work characteristics) on risk tolerance are larger than that of internal factors (personal subjective perception and work knowledge & experiences). Specifically, safety management contributes the most to workers' safety risk tolerance through its direct effect and indirect effect; while personal subjective perception comes the second and can act as an intermedia for work characteristics. This research provides an in-depth insight of workers' unsafe behaviors by depicting the contributing factors as shown in the accident causal model developed in this research. PMID:26775077

  4. Factors That Influence the Practice of Elective Induction of Labor

    PubMed Central

    Moore, Jennifer; Low, Lisa Kane

    2012-01-01

    Elective induction of labor has been linked to increased rates of prematurity and rising rates of cesarean birth. The purpose of this investigation was to evaluate current trends in induction of labor scholarship focusing on evidence-based factors that influence the practice of elective induction. A key word search was conducted to identify studies on the practice of elective induction of labor. Analysis of the findings included clustering and identification of recurrent themes among the articles with 3 categories being identified. Under each category, the words/phrases were further clustered until a construct could be named. A total of 49 articles met inclusion criteria: 7 patient, 6 maternity care provider, and 4 organization factors emerged. Only 4 of the articles identified were evidence based. Patient factors were divided into preferences/convenience, communication, fear, pressure/influence, trust, external influences, and technology. Provider factors were then divided into practice preferences/convenience, lack of information, financial incentives, fear, patient desire/demand, and technology. Organization factors were divided into lack of enforcement/accountability, hospital culture, scheduling of staff, and market share issues. Currently, there is limited data-based information focused on factors that influence elective induction of labor. Despite patient and provider convenience/preferences being cited in the literature, the evidence does not support this practice. PMID:22843006

  5. Cow's milk and goat's milk.

    PubMed

    Turck, Dominique

    2013-01-01

    Cow's milk is increasingly suggested to play a role in the development of chronic degenerative, non-communicable disorders whereas goat's milk is advocated as having several health benefits. Cow's milk is a rich and cheap source of protein and calcium, and a valuable food for bone health. Despite their high content in saturated fats, consumption of full-fat dairy products does not seem to cause significant changes in cardiovascular disease risk variables. Early introduction of cow's milk is a strong negative determinant of iron status. Unmodified cow's milk does not meet nutritional requirements of infants although it is acceptable to add small volumes of cow's milk to complementary foods. Cow's milk protein allergy has a prevalence ranging from 2 to 7%, and the age of recovery is usually around 2-3 years. The evidence linking cow's milk intake to a later risk of type 1 diabetes or chronic degenerative, non-communicable disorders (obesity, metabolic syndrome, type 2 diabetes, hypertension) is not convincing. Milk probably protects against colorectal cancer, diets high in calcium are a probable cause of prostate cancer, and there is limited evidence suggesting that high consumption of milk and dairy products increases the risk for prostate cancer. There is no evidence to support the use of a cow's milk-free diet as a primary treatment for individuals with autistic spectrum disorders. Unmodified goat's milk is not suitable for infants because of the high protein and minerals content and of a low folate content. Goat's milk has no clear nutritional advantage over cow's milk and is not less allergenic. The European Food Safety Authority recently stated that proteins from goat's milk can be suitable as a protein source for infant and follow-on formula, provided the final product complies with the compositional criteria laid down in Directive 2006/141/EC. PMID:24029787

  6. Effect of intravenous bovine growth hormone or human pancreatic growth hormone-releasing factor on milk production and plasma hormones and metabolites in sheep.

    PubMed

    Hart, I C; Chadwick, P M; James, S; Simmonds, A D

    1985-05-01

    Although it is well known that exogenous bovine GH (bGH) increases milk yield in ruminants it has not been possible to determine whether an increase in endogenous GH secretion has the same effect. The recent isolation of human pancreatic GH-releasing factor (hpGRF-44) has enabled this comparison of the effects of bGH and hpGRF-44 on milk production in sheep. Three pairs of Dorset ewes underwent three 4-day treatments according to a Latin square design. Treatment 1 involved: 2-hourly i.v. injections (approximately 3.0 ml) of bGH (15 micrograms/kg; 1.8 units/mg); treatment 2: 2-hourly i.v. injections (approximately 3.0 ml) of hpGRF-44 (0.6 microgram/kg); treatment 3: 2-hourly i.v. injections (3.0 ml) of the vehicle. Treatment periods were separated by 10 days. Sheep were milked twice daily and the milk was analysed for fat, protein and lactose. Blood samples (5.0 ml) were taken before and at 15, 45, 75 and 100 min after every third injection throughout the 4 days. Plasma was analysed for insulin, glucose, urea and non-esterified fatty acids (NEFA). The changes in plasma GH stimulated by hpGRF-44 were consistent and repeatable throughout the 4 days of treatment.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:3921646

  7. Effects of exposure to artificial long days on milk yield, maternal insulin-like growth factor 1 levels and kid growth rate in subtropical goats.

    PubMed

    Hernández, Horacio; Flores, José Alfredo; Delgadillo, José Alberto; Fernández, Ilda G; Flores, Manuel de Jesús; Mejía, Ángel; Elizundia, José Manuel; Bedos, Marie; Ponce, José Luis; Ramírez, Sergio

    2016-04-01

    This study was designed to determine whether any relationship exists between exposure to artificial long days, milk yield, maternal plasma insulin-like growth factor 1 (IGF-1) levels, and kid growth rate in goats. One group of lactating goats was maintained under naturally decreasing day length (control group; n = 19), while in another one, they were kept under artificial long days (LD group; n = 19). Milk yield was higher in goats from the LD group than that in the control group (P < 0.05). Maternal IGF-1 levels at day 57 of lactation were higher (P < 0.05) in goats from the LD group than the levels in the control group and were positively correlated with the total milk yields per goat at days 43 and 57 of lactation (r = 0.77 and r = 0.84, respectively; P < 0.01). Daily weight gain at week 4 was higher (P < 0.01) in kids from the LD group than that in kids from the control group and was correlated with total and average IGF-1 maternal levels (r = 0.60 and r = 0.60, P < 0.05). It was concluded that submitting lactating goats to artificial long days increases milk yield, plasma IGF-1 maternal levels and the growth rate of the kids. PMID:26261065

  8. Shiga Toxin-Producing Escherichia coli Isolated from Bovine Mastitic Milk: Serogroups, Virulence Factors, and Antibiotic Resistance Properties

    PubMed Central

    Momtaz, Hassan; Safarpoor Dehkordi, Farhad; Taktaz, Taghi; Rezvani, Amir; Yarali, Sajad

    2012-01-01

    The aim of this study was to detect the virulence factors, serogroups, and antibiotic resistance properties of Shiga toxin-producing Escherichia coli, by using 268 bovine mastitic milk samples which were diagnosed using California Mastitis Test. After E. coli identification, PCR assays were developed for detection of different virulence genes, serogroups, and antibiotic resistance genes of Escherichia coli. The antibiotic resistance pattern was studied using disk diffusion method. Out of 268 samples, 73 (27.23%) were positive for Escherichia coli, and, out of 73 positive samples, 15 (20.54%) were O26 and 11 (15.06%) were O157 so they were the highest while O111 was not detected in any sample so it was the lowest serogroup. Out of 73 STEC strains, 11 (15.06%) and 36 (49.31%) were EHEC and AEEC, respectively. All of the EHEC strains had stx1, eaeA, and ehly, virulence genes, while in AEEC strains stx1 had the highest prevalence (77.77%), followed by eaeA (55.55%). Totally, aadA1 (65.95%) had the highest while blaSHV (6.38%) had the lowest prevalence of antibiotic resistance genes. The disk diffusion method showed that the STEC strains had the highest resistance to penicillin (100%), followed by tetracycline (57.44%), while resistance to cephalothin (6.38%) was the lowest. PMID:23213293

  9. Milk Fat Content and DGAT1 Genotype Determine Lipid Composition of the Milk Fat Globule Membrane

    PubMed Central

    Argov-Argaman, Nurit; Mida, Kfir; Cohen, Bat-Chen; Visker, Marleen; Hettinga, Kasper

    2013-01-01

    During secretion of milk fat globules, triacylglycerol (TAG) droplets are enveloped by a phospholipid (PL) trilayer. Globule size has been found to be related to polar lipid composition and fat content, and milk fat content and fatty acid composition have been associated with the diacylglycerol acyltransferase 1 (DGAT1) K232A polymorphism; however, the association between the DGAT1 polymorphism and fat globule size and polar lipid composition has not been studied. The ratio between polar and neutral lipids as well as the composition of the polar lipids in milk has industrial as well as nutritional and health implications. Understanding phenotypic and genotypic factors influencing these parameters could contribute to improving milk lipid composition for dairy products. The focus of the present study was to determine the effect of both fat content and DGAT1 polymorphism on PL/TAG ratio, as a marker for milk fat globule size, and detailed PL composition. Milk samples were selected from 200 cows such that there were equal numbers of samples for the different fat contents as well as per DGAT1 genotype. Samples were analyzed for neutral and polar lipid concentration and composition. PL/TAG ratio was significantly associated with both fat content and DGAT1 genotype. Phosphatidylinositol and phosphatidylserine concentrations were associated with fat content*DGAT1 genotype with a stronger association for the AA than the KK genotype. Sphingomyelin concentration tended to interact with fat content*DGAT1 genotype. Phosphatidylethanolamine (PE) concentration showed a biphasic response to fat content, suggesting that multiple biological processes influence its concentration. These results provide a new direction for controlling polar lipid concentration and composition in milk through selective breeding of cows. PMID:23874734

  10. Influence analysis for the factor analysis model with ranking data.

    PubMed

    Xu, Liang; Poon, Wai-Yin; Lee, Sik-Yum

    2008-05-01

    Influence analysis is an important component of data analysis, and the local influence approach has been widely applied to many statistical models to identify influential observations and assess minor model perturbations since the pioneering work of Cook (1986). The approach is often adopted to develop influence analysis procedures for factor analysis models with ranking data. However, as this well-known approach is based on the observed data likelihood, which involves multidimensional integrals, directly applying it to develop influence analysis procedures for the factor analysis models with ranking data is difficult. To address this difficulty, a Monte Carlo expectation and maximization algorithm (MCEM) is used to obtain the maximum-likelihood estimate of the model parameters, and measures for influence analysis on the basis of the conditional expectation of the complete data log likelihood at the E-step of the MCEM algorithm are then obtained. Very little additional computation is needed to compute the influence measures, because it is possible to make use of the by-products of the estimation procedure. Influence measures that are based on several typical perturbation schemes are discussed in detail, and the proposed method is illustrated with two real examples and an artificial example. PMID:18482479

  11. Cows' milk protein-sensitive enteropathy. An important factor in prolonging diarrhoea of acute infective enteritis in early infancy.

    PubMed Central

    Iyngkaran, N; Robinson, M J; Sumithran, E; Lam, S K; Puthucheary, S D; Yadav, M

    1978-01-01

    The possible role of cows' milk protein in prolonging diarrhoea in very young infants with acute infective enteritis was studied in 14 infants, 9 under the age of 2 months and 5 older than 6 months. Bacterial pathogens were isolated from the stools of 4 infants from the younger age group. After appropriate initial treatment the infants were maintained on a cows' milk protein-free formula. 6 weeks later jejunal biopsies were performed before and 24 hours after challenge with a low lactose cows' milk protein formula. The immunoglobulin and complement levels in the serum and duodenal juice were also estimated at these times. Attempts to isolate bacterial and viral pathogens in stools were again made in all patients. The 5 older infants clinically tolerated cows' milk protein and their pre- and postchallenge jejunal biopsies were within normal limits. However, significant histological changes were observed in the postchallenge jejunal biopsies of all 9 infants under 2 months of age. In addition, 5 of these infants developed diarrhoea. This suggests that the jejunal mucosa of very young infants previously fed a cows' milk protein-based formula and who contract infective enteritis suffers damage when rechallenged with cows' milk protein. PMID:646417

  12. Dioxins levels in breast milk of women living in Caserta and Naples: assessment of environmental risk factors.

    PubMed

    Giovannini, Armando; Rivezzi, Gaetano; Carideo, Pietro; Ceci, Roberta; Diletti, Gianfranco; Ippoliti, Carla; Migliorati, Giacomo; Piscitelli, Prisco; Ripani, Alessandro; Salini, Romolo; Scortichini, Giampiero

    2014-01-01

    Naples and Caserta provinces are extensively affected by the illegal dumping of hazardous and urban wastes, which were periodically set to fire. Several studies were made on the possible health impact of this illegal waste management. The aim of the study was to detect dioxins levels in breast milk of volunteer primiparae and to assess the possible source of dioxins in the affected areas. The authors determined dioxins levels in breast milk from 100 primiparae from the study area and collected anamnestic information on donors. We determined dioxins levels in breast milk from 100 primiparae from the study area and collected anamnestic information on donors. As a measure of environmental risk of dioxins (EDR) we used the interpolated values of dioxins concentration in buffalo milk samples collected in the study area. Correlations between the EDR, age of the mother, smoking habit, cheese consumption, occupation in activity at risk, presence of plants for the disposal of toxic waste or illegal burning of solid waste near the residence of the donor and dioxin level in breast milk were investigated. The dioxin level in breast milk is significantly correlated to the EDR, the age of the sampled women and the presence of illegal burning of solid waste. PMID:24120012

  13. Influence of Reproduction on Stable-Isotope Ratios: Nitrogen and Carbon Isotope Discrimination between Mothers, Fetuses, and Milk in the Fin Whale, a Capital Breeder.

    PubMed

    Borrell, A; Gómez-Campos, E; Aguilar, A

    2016-01-01

    In mammals, the influence of gestation and lactation on the tissue stable-isotope ratios of females, fetuses, and milk remains poorly understood. Here we investigate the incidence of these events on δ(13)C and δ(15)N values in fin whales sampled off northwestern Spain between 1983 and 1985. The effect of gestation on tissue stable-isotope ratios was examined in the muscle of pregnant females (n = 13) and their fetuses (n = 10) and that of lactation in the muscle of nursing females (n = 21) and their milk (n = 25). Results suggest that fetuses are enriched compared to their mothers in both (15)N (Δ(15)N = 1.5‰) and (13)C (Δ(13)C =1.1‰), while, compared to muscle, milk is enriched in (15)N (Δ(15)N = 0.3‰) but depleted in (13)C (Δ(13)C = -0.62‰). This pattern is consistent with that previously observed for other species that, like the fin whale, rely on endogenous energy during reproduction, and it substantiates a general difference in the physiological processing of nitrogen and carbon balances between income and capital breeders. These findings are relevant to the understanding of the energetic balance of mammals during gestation and lactation and are central when inferences on trophic ecology are drawn from isotopic values of reproductive females. PMID:27082523

  14. Maternal High-Fat Diet during Pregnancy and Lactation Influences Obestatin and Ghrelin Concentrations in Milk and Plasma of Wistar Rat Dams and Their Offspring

    PubMed Central

    Słupecka, Monika; Romanowicz, Katarzyna; Woliński, Jarosław

    2016-01-01

    The study aims to establish the effect of a maternal high-fat diet on obestatin concentration, total ghrelin, and ghrelin/obestatin ratio during pregnancy and lactation of Wistar rats and their offspring in the first 21 days of life. On the mating day, females were randomly allocated and fed either a high-fat diet (30% of fat; HF) or breeding diet (5% fat; BD) till the 21st day of lactation. Hormones were analyzed in the blood plasma and milk of rat dams as well as in the blood plasma of their offspring. HF resulted in a significant decrease in obestatin level on the 14th day of lactation and elevation on the 21st day. Plasma obestatin in HFD offspring was significantly higher than in BD ones. HF diet did not significantly affect dam plasma ghrelin until the 21st day of lactation. The ghrelin concentrations in milk after both diets were significantly lower than in blood plasma. Milk ghrelin in HF dams was significantly higher than in the BD ones. Plasma ghrelin from HF offspring was significantly higher than that from BD dams. Our results demonstrate that a maternal HF diet during pregnancy and lactation influences ghrelin and obestatin level in both dams and their offspring. PMID:27127509

  15. Estimates of marker effects for measures of milk flow in the Italian brown Swiss dairy cattle population

    PubMed Central

    2012-01-01

    Background Milkability is a complex trait that is characterized by milk flow traits including average milk flow rate, maximum milk flow rate and total milking time. Milkability has long been recognized as an economically important trait that can be improved through selection. By improving milkability, management costs of milking decrease through reduced labor and improved efficiency of the automatic milking system, which has been identified as an important factor affecting net profit. The objective of this study was to identify markers associated with electronically measured milk flow traits, in the Italian Brown Swiss population that could potentially improve selection based on genomic predictions. Results Sires (n = 1351) of cows with milk flow information were genotyped for 33,074 single nucleotide polymorphism (SNP) markers distributed across 29 Bos taurus autosomes (BTA). Among the six milk flow traits collected, ascending time, time of plateau, descending time, total milking time, maximum milk flow and average milk flow, there were 6,929 (time of plateau) to 14,585 (maximum milk flow) significant SNP markers identified for each trait across all BTA. Unique regions were found for each of the 6 traits providing evidence that each individual milk flow trait offers distinct genetic information about milk flow. This study was also successful in identifying functional processes and genes associated with SNPs that influences milk flow. Conclusions In addition to verifying the presence of previously identified milking speed quantitative trait loci (QTL) within the Italian Brown Swiss population, this study revealed a number of genomic regions associated with milk flow traits that have never been reported as milking speed QTL. While several of these regions were not associated with a known gene or QTL, a number of regions were associated with QTL that have been formerly reported as regions associated with somatic cell count, somatic cell score and udder morphometrics

  16. Analysis of the N-glycans of recombinant human Factor IX purified from transgenic pig milk

    PubMed Central

    Gil, Geun-Cheol; Velander, William H; Van Cott, Kevin E

    2008-01-01

    Glycosylation of recombinant proteins is of particular importance because it can play significant roles in the clinical properties of the glycoprotein. In this work, the N-glycan structures of recombinant human Factor IX (tg-FIX) produced in the transgenic pig mammary gland were determined. The majority of the N-glycans of transgenic pig-derived Factor IX (tg-FIX) are complex, bi-antennary with one or two terminal N-acetylneuraminic acid (Neu5Ac) moieties. We also found that the N-glycan structures of tg-FIX produced in the porcine mammary epithelial cells differed with respect to N-glycans from glycoproteins produced in other porcine tissues. tg-FIX contains no detectable Neu5Gc, the sialic acid commonly found in porcine glycoproteins produced in other tissues. Additionally, we were unable to detect glycans in tg-FIX that have a terminal Galα(1,3)Gal disaccharide sequence, which is strongly antigenic in humans. The N-glycan structures of tg-FIX are also compared to the published N-glycan structures of recombinant human glycoproteins produced in other transgenic animal species. While tg-FIX contains only complex structures, antithrombin III (goat), C1 inhibitor (rabbit), and lactoferrin (cow) have both high mannose and complex structures. Collectively, these data represent a beginning point for the future investigation of species-specific and tissue/cell-specific differences in N-glycan structures among animals used for transgenic animal bioreactors. PMID:18456721

  17. Computer Visualizations: Factors that Influence Spatial Anatomy Comprehension

    ERIC Educational Resources Information Center

    Nguyen, Ngan; Nelson, Andrew J.; Wilson, Timothy D.

    2012-01-01

    Computer visualizations are increasingly common in education across a range of subject disciplines, including anatomy. Despite optimism about their educational potential, students sometime have difficulty learning from these visualizations. The purpose of this study was to explore a range of factors that influence spatial anatomy comprehension…

  18. Consumers with Major Depressive Disorder: Factors Influencing Job Placement

    ERIC Educational Resources Information Center

    Hergenrather, Kenneth C.; Haase, Eileen; Zeglin, Robert J.; Rhodes, Scott D.

    2013-01-01

    The theory of planned behavior (TPB) was applied to study the factors that influence the intention of public rehabilitation placement professionals to place consumers with major depressive disorder (MDD) in jobs. A sample of 108 public rehabilitation placement professionals in the Mid-Atlantic region of the United States completed the MDD…

  19. Factors Influencing the Development of PTSD in Battered Women.

    ERIC Educational Resources Information Center

    Cimino, Joseph J.; Dutton, Mary Ann

    In this study an interactive conceptual model was utilized in an attempt to examine variables which contribute to, and influence, the development of Post Traumatic Stress Disorder (PTSD) in battered women. This model considers the individual's response to trauma as being the product of the interaction between factors related to the characteristics…

  20. Factors Influencing Role Behaviors by Professional Exemplars in Hospitals

    ERIC Educational Resources Information Center

    Bolding, Deborah J.

    2013-01-01

    This basic qualitative study explored factors that influenced the development of professional role behaviors of nurses, occupational and physical therapists who were characterized as exemplars in the acute hospital setting. The participants, four occupational therapists, four nurses, and four physical therapists were interviewed using a…

  1. Factors Influencing Practical Training Quality in Iranian Agricultural Higher Education

    ERIC Educational Resources Information Center

    Mojarradi, Gholamreza; Karamidehkordi, Esmail

    2016-01-01

    This paper presents an analysis of the factors influencing the practical training quality of agricultural higher education programmes from the senior students' perspective. The study was conducted in two public universities located in the north-west of Iran using a cross-sectional survey and structured interviews with a randomised sample of 254…

  2. Factors Influencing Knowledge Creation and Innovation in an Organisation

    ERIC Educational Resources Information Center

    Merx-Chermin, Mireille; Nijhof, Wim, J.

    2005-01-01

    Purpose: The purpose of this study is to gain a better understanding of the factors that influence the innovative power of organisations. The concept of innovation and innovative power was examined by analysing the relationship between the construct of the learning organisation, knowledge organisation and innovative organisation, and has resulted…

  3. Police Management Training Factors Influencing DWI Arrests. Final Report.

    ERIC Educational Resources Information Center

    Bishop, Edward W.

    The development of training material for police management personnel concerning command and supervisory actions appropriate for more effective driving-while-intoxicated (DWI) enforcement is desired. The training is based on two research studies that identified environmental and attitudinal factors influencing a patrolman's arrest decision. These…

  4. Factors Influencing Residents' Satisfaction in Residential Aged Care

    ERIC Educational Resources Information Center

    Chou, Shu-Chiung; Boldy, Duncan P.; Lee, Andy H.

    2003-01-01

    Purpose: The aim of this study was to identify the important factors influencing residents' satisfaction in residential aged care and to provide a better understanding of their interrelationships. Design and Methods: A cross-sectional survey design was used to collect the required information, including resident satisfaction, resident dependency…

  5. Factors Influencing School Choice in a School District in Delaware

    ERIC Educational Resources Information Center

    Kennedy, John J., Jr.

    2012-01-01

    The purpose of this descriptive study is to examine the factors that influenced parents in a school district in Delaware when they selected a high school for their child. This study also sought to examine the sources of information that parents used. Also examined was the impact of socio-economic status in the high school selection process. A…

  6. Factors that Influence Women's Technical Skill Development in Outdoor Adventure

    ERIC Educational Resources Information Center

    Warren, Karen; Loeffler, TA

    2006-01-01

    This article provides a theoretical foundation for understanding women's technical skill development (TSD) in outdoor adventure. An examination of societal and biological factors influencing women's TSD focuses on gender role socialization, sense of competence, technical conditioning, sexism, spatial ability, and risk-taking. The article suggests…

  7. Factors Influencing Teachers' Engagement in Informal Learning Activities

    ERIC Educational Resources Information Center

    Lohman, Margaret C.

    2006-01-01

    Purpose: The purpose of this study is to examine factors influencing the engagement of public school teachers in informal learning activities. Design/methodology/approach: This study used a survey research design. Findings: Analysis of the data found that teachers rely to a greater degree on interactive than on independent informal learning…

  8. Factors Influencing the Adoption of Multimedia Cable Technology.

    ERIC Educational Resources Information Center

    Lin, Carolyn A.; Jeffres, Leo W.

    1998-01-01

    Integrates several mainstream research approaches to new media diffusion to explore the potential strengths and weaknesses of each. Investigates factors influencing multimedia cable service adoption interest, including demographic variables, existing media-use patterns, and personality traits such as "innovativeness." (SR)

  9. Factors Influencing Federal Employee Worker Satisfaction: A Baseline Study.

    ERIC Educational Resources Information Center

    Schmidt, Wallace V.; And Others

    Utilizing data from the Federal Employee Attitude Survey, 1979, a survey was distributed to a stratified random sample of 20,000 employees to identify and analyze the factors influencing federal employee worker satisfaction. Questions on the survey ranged from demographics to personal evaluations of the work environment as recorded on a…

  10. Factors That Influence the Attrition of Mentors in Rural Areas

    ERIC Educational Resources Information Center

    Givens, Sharon Leenese

    2012-01-01

    This research is a qualitative case study exploring the factors that influence the attrition of mentors in rural areas. Mentoring initiatives and programs have proliferated throughout schools in an effort to provide students with positive role models, increase graduation rates and improve overall performance Mentoring programs are an increasingly…

  11. Factors that Influence Information Systems Undergraduates to Pursue IT Certification

    ERIC Educational Resources Information Center

    Hunsinger, D. Scott; Smith, Michael A.

    2008-01-01

    We identify factors that influence the intent of undergraduate information systems majors to pursue IT certification. Previous research has revealed that IT/IS hiring managers may use certification as a job requirement or to differentiate between job candidates with similar levels of education and experience. As well, salary surveys have shown…

  12. What Factors Influence Vietnamese Students' Choice of University?

    ERIC Educational Resources Information Center

    Dao, Mai Thi Ngoc; Thorpe, Anthony

    2015-01-01

    Purpose: The purpose of this paper is to report the factors that influence Vietnamese students' choice of university in a little researched context where the effects of globalization and education reform are changing higher education. Design/methodology/approach: A quantitative survey was completed by 1,124 current or recently completed university…

  13. Factors Influencing Exemplary Science Teachers' Levels of Computer Use

    ERIC Educational Resources Information Center

    Hakverdi, Meral; Dana, Thomas M.; Swain, Colleen

    2011-01-01

    The purpose of this study was to examine exemplary science teachers' use of technology in science instruction, factors influencing their level of computer use, their level of knowledge/skills in using specific computer applications for science instruction, their use of computer-related applications/tools during their instruction, and their…

  14. Factors that Influence Informal Learning in the Workplace

    ERIC Educational Resources Information Center

    Berg, Shelley A.; Chyung, Seung Youn

    2008-01-01

    Purpose: The purpose of this research is to investigate factors that influence informal learning in the workplace and the types of informal learning activities people engage in at work. More specifically, the research examined: the relationship between informal learning engagement and the presence of learning organization characteristics; and…

  15. Abuse of Working Children and Influencing Factors, Turkey

    ERIC Educational Resources Information Center

    Oncu, Emine; Kurt, Ahmet Oner; Esenay, Figen Isik; Ozer, Fatma

    2013-01-01

    Objective: The study was planned as the research of the kind/kinds of abuse and the factors influencing the abuse that the children under 18 who are working full-time at a workplace and enrolled in a vocational training center subjected to. Method: Questionnaires were administered to 595 apprentices who were attending a vocational training center.…

  16. Key Factors that Influence Recruiting Young Chinese Students

    ERIC Educational Resources Information Center

    Wang, Zhenmin

    2007-01-01

    The discussion in this paper is based on the assumption that international education is equated to recruiting and educating international students, even though its true concept goes far beyond this narrow understanding. The purpose of this research is to look at the key factors that influence recruiting young Chinese students, and make sure all…

  17. Social and Environmental Factors Influencing In-Prison Drug Use

    ERIC Educational Resources Information Center

    Woodall, James

    2012-01-01

    Purpose: There is a strong political imperative to regard the prison as a key social setting for health promotion, but evidence indicates that drug misuse continues to be a significant issue for many prisoners. This paper aims to examine the social and environmental factors within the setting that influence individuals' drug taking.…

  18. Factors Influencing Career Choice of Management Students in India

    ERIC Educational Resources Information Center

    Agarwala, Tanuja

    2008-01-01

    Purpose: This paper aims to explore the influence of a range of factors on the career choice of management students in India. The importance of different individuals in the family and at work in making career choices among these students is also to be explored. In addition, the study seeks to address the relationship of the cultural values of…

  19. Multilevel Factors Influencing Maternal Stress during the First Three Years.

    ERIC Educational Resources Information Center

    Mulsow, Miriam; Caldera, Yvonne M.; Pursley, Marta; Reifman, Alan; Huston, Aletha C.

    2002-01-01

    Study applies family stress theory to the influence of personal, child, and familial factors on a mother's parenting stress during the first 3 years of her infant's life. Mother's personality was most predictive of parenting stress. Counterintuitively, mothers who were more satisfied with work or school choices were more likely to be chronically…

  20. Factors Influencing Faculty Engagement--Then, Now, and Future

    ERIC Educational Resources Information Center

    Holland, Barbara A.

    2016-01-01

    In this commentary, author Barbara Holland reflects on her 1999 "Journal of Public Service & Outreach" article, "Factors and Strategies That Influence Faculty Involvement in Public Service" (EJ589785) reprinted in this 20th anniversary issue of "Journal of Higher Education Outreach and Engagement." In the late…

  1. Factors That Influence the Understanding of Good Mathematics Teaching

    ERIC Educational Resources Information Center

    Leong, Kwan Eu

    2013-01-01

    This study explored the factors that influenced the understanding of good mathematics teaching. A mixed methodology was used investigate the beliefs of beginning secondary teachers on good mathematics teaching. The two research instruments used in this study were the survey questionnaire and an interview. Beginning teachers selected Immediate…

  2. Factors Influencing Students' Decisions about Post-Year 10 Education

    ERIC Educational Resources Information Center

    Beswick, Kim; Hay, Ian; Watson, Jane; Allen, Jeanne; Cranston, Neil

    2012-01-01

    This paper reports pilot data from an instrument devised as part of a large ARC funded project that aims, among other things, to investigate factors that influence the decisions of students in rural and/or disadvantaged areas to continue their schooling beyond Year 10. One section of the pilot student questionnaire comprised 42 items designed to…

  3. Factors Influencing the Dielectric Properties of Agricultural and Food Materials

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Dielectric properties of materials are defined, and the major factors that influence these properties of agricultural and food materials, namely, frequency of the applied radio-frequency or microwave electric fields, and water content, temperature, and density of the materials, are discussed on the ...

  4. Environmental Volunteers: Factors Influencing Their Involvement in Environmental Action

    ERIC Educational Resources Information Center

    Liarakou, Georgia; Kostelou, Eleni; Gavrilakis, Costas

    2011-01-01

    The aim of the present study was to investigate the factors that influence volunteers to become involved in environmental action. The research focused on volunteers undertaking action in summer camps organised by an environmental non-governmental organisation (NGO) in Greece. The results suggest that the environmental issues addressed in volunteer…

  5. Factors Influencing Active Learning in Small Enterprises. Working Paper.

    ERIC Educational Resources Information Center

    Hawke, Geof

    The factors influencing active learning in small enterprises were examined. Data from earlier Australian studies were examined in an attempt to provide a framework that might inform the relationship between educational systems and small enterprises. Special attention was paid to a 1988 study of systematic differences between small businesses that…

  6. Against Conventional Wisdom: Factors Influencing Hispanic Students' Reading Achievement

    ERIC Educational Resources Information Center

    Percell, Jay C.; Kaufman, Kristina

    2013-01-01

    The researchers performed a variable analysis of the 2002 Educational Longitudinal Study data investigating factors that influence students' reading scores on standardized tests. Hispanic and non-Hispanic Scores were analyzed and controlling variables were compared to determine the effect of each on both populations. Certain variables commonly…

  7. Factors Influencing the Vocational Aspirations of Victorian Year 9 Students.

    ERIC Educational Resources Information Center

    Schrom, Linda K.

    A study was conducted to determine the influence of family background and attitudinal factors on occupational aspirations of Year 9 students in Victoria, Australia. A survey was made of all Victorian Year 9 students and comparisons were made between groups of students who aspired to different occupations. Discriminant function analyses were…

  8. Factors Influencing the Readability of Student-Generated Texts.

    ERIC Educational Resources Information Center

    Allen, JoBeth

    An investigation examined student-generated texts in terms of both traditional and more theoretically valid readability to determine what factors influence comprehension when children read their own, peer, and adult-written texts. Seventy dictated stories created in an earlier study, along with 4 first-grade level stories from the "Reader's Digest…

  9. Factors Influencing Stress, Burnout, and Retention of Secondary Teachers

    ERIC Educational Resources Information Center

    Fisher, Molly H.

    2011-01-01

    This study examines the stress, burnout, satisfaction, and preventive coping skills of nearly 400 secondary teachers to determine variables contributing to these major factors influencing teachers. Analysis of Variance (ANOVA) statistics were conducted that found the burnout levels between new and experienced teachers are significantly different,…

  10. Factors Influencing the Occurrence of Adult Agricultural Education Programs.

    ERIC Educational Resources Information Center

    Christmas, Oren L.; Warmbrod, J. Robert

    A study examined the institutional factors the influence whether or not adult agricultural education programs are offered in high schools. All Ohio secondary schools that offered vocational agriculture programs in agricultural production or farm business management during 1985-1986 (a total of 260 schools) were included in the study. Data were…

  11. Factors influencing dissolution of carbonaceous materials in liquid iron

    SciTech Connect

    Sun, H.P.

    2005-12-01

    Carbon dissolution into liquid iron was investigated by a kinetic model assuming the rate is limited by interfacial carbon dissociation and mass transfer in the liquid iron. The rate influencing factors and the inter-relations among them were discussed with the aid of the kinetic model.

  12. External and Internal Factors Influencing Happiness in Elite Collegiate Athletes

    ERIC Educational Resources Information Center

    Denny, Katherine G.; Steiner, Hans

    2009-01-01

    When under conditions of high demand and allostatic load, are happiness and satisfaction in four domains (family, friends, academics, recreation) influenced more by external or internal factors? Do student-athletes who lead exceedingly complicated lives report happiness as a function of athletic achievement or internal disposition? Stanford…

  13. Factors Influencing Consent to Having Videotaped Mental Health Sessions

    ERIC Educational Resources Information Center

    Ko, Kenton; Goebert, Deborah

    2011-01-01

    Objective: The authors critically reviewed the literature regarding factors influencing consent to having videotaped mental health sessions. Methods: The authors searched the literature in PubMed, PsycINFO, Google Scholar, and Web of Science from the mid-1950s through February 2009. Results: The authors identified 27 studies, of which 19 (73%)…

  14. Analysis on Influence Factors of Adaptive Filter Acting on ANC

    NASA Astrophysics Data System (ADS)

    Zhang, Xiuqun; Zou, Liang; Ni, Guangkui; Wang, Xiaojun; Han, Tao; Zhao, Quanfu

    The noise problem has become more and more serious in recent years. The adaptive filter theory which is applied in ANC [1] (active noise control) has also attracted more and more attention. In this article, the basic principle and algorithm of adaptive theory are both researched. And then the influence factor that affects its covergence rate and noise reduction is also simulated.

  15. Factors Influencing BI Data Collection Strategies: An Empirical Investigation

    ERIC Educational Resources Information Center

    Ramakrishnan, Thiagarajan

    2010-01-01

    The purpose of this dissertation is to examine the external factors that influence an organizations' business intelligence (BI) data collection strategy when mediated by BI attributes. In this dissertation, data warehousing strategies are used as the basis on which to frame the exploration of BI data collection strategies. The attributes include…

  16. Factors That Influence Faculty Adoption of Learning-Centered Approaches

    ERIC Educational Resources Information Center

    Blumberg, Phyllis

    2016-01-01

    This article proposes a recommended course of action for faculty development based upon Rogers' theory of Diffusion of Innovations and data collected in a study looking at the prevalence of use of learning-centered teaching practices. Specific faculty development strategies are aligned with Rogers' factors influencing decisions to adopt…

  17. Factors Influencing Undergraduates' Self-Evaluation of Numerical Competence

    ERIC Educational Resources Information Center

    Tariq, Vicki N.; Durrani, Naureen

    2012-01-01

    This empirical study explores factors influencing undergraduates' self-evaluation of their numerical competence, using data from an online survey completed by 566 undergraduates from a diversity of academic disciplines, across all four faculties at a post-1992 UK university. Analysis of the data, which included correlation and multiple regression…

  18. Factors Influencing Consent for Electronic Data Linkage in Urban Latinos.

    PubMed

    Bakken, Suzanne; Yoon, Sunmoo; Suero-Tejeda, Niurka

    2015-01-01

    Within the context of patient participation in a Learning Health System, this study examined consent rates and factors associated with consent for linking survey data with electronic clinical data in a sample of 2,271 Latinos. Consent rate was 96.3%. Government insurance status and health literacy significantly influenced the odds of consent. PMID:26262286

  19. FACTORS INFLUENCING FALL FOLIAGE COLOR EXPRESSION IN SUGAR MAPLE TREES.

    EPA Science Inventory

    Abstract: We evaluated factors influencing red autumn coloration in leaves of sugar maple (Acer saccharum Marsh.) by measuring mineral nutrition and carbohydrate concentrations, moisture content, and phenology of color development of leaves from 16 mature open-grown trees on 12 d...

  20. Improving Performance Appraisals: Confronting Subjective Factors That Influence Ratings.

    ERIC Educational Resources Information Center

    Kruger, Michael J.

    1986-01-01

    Explores implications of subjective factors that influence rating processes upon which formal performance appraisal systems are based and presents a strategy for addressing this problem which utilizes the critical incident method to focus objectively on employee behavior. A performance feedback worksheet to be utilized with this appraisal method…

  1. Factors Influencing Latino Participation in Community-Based Diabetes Education

    ERIC Educational Resources Information Center

    Francis, Sarah L.; Noterman, Amber; Litchfield, Ruth

    2014-01-01

    An Extension diabetes program (DP) was revised for Latinos; however, participation was limited. Factors influencing low participation rates were examined. Five Latinos interested in the DP participated in a focus group discussion. Transcripts were analyzed for themes. Preferred education programs were multi-session, local, group classes led by an…

  2. Adolescents Who Drive Under the Influence: Correlates and Risk Factors.

    ERIC Educational Resources Information Center

    Mayton, Daniel M., II; And Others

    This study was designed to determine the correlates or potential risk factors which predict whether an adolescent who drinks or uses drugs will refrain from driving under the influence, or will drive in this condition. A group of 426 rural high school seniors completed a questionnaire which assessed drug use patterns and previously identified risk…

  3. Factors Influencing Adjustment to Late-Life Divorce.

    ERIC Educational Resources Information Center

    Wilson, Keren Brown; DeShane, Michael R.

    Although the rate of divorce among older Americans has increased steadily, little attention has been paid to late life divorce. To describe the role of age and other factors which might influence adjustment to divorce in later life, data from a larger pilot study were used: 81 divorced persons over the age of 60 completed in-depth, structured…

  4. Factors Influencing Student Participation in College Study Abroad Programs

    ERIC Educational Resources Information Center

    Bandyopadhyay, Soumava; Bandyopadhyay, Kakoli

    2015-01-01

    This paper proposes a theoretical framework to investigate the factors that influence student participation in college study abroad programs. The authors posit that students' general perceptions regarding the study abroad experience and their expectations of intercultural awareness from study abroad programs will impact their perceptions of…

  5. Factors Influencing Secondary School Teachers' Adoption of Teaching Blogs

    ERIC Educational Resources Information Center

    Lai, Hui-Min; Chen, Chin-Pin

    2011-01-01

    Recently, there has been a significant proliferation in the number of teaching blogs; however, little has been explored about what motivates teachers to adopt teaching blogs. The purpose of this study is to find out which factors can significantly influence teacher decisions regarding their teaching blog adoption and the relative importance of…

  6. Factors that Influence Elementary Teachers Use of Computers

    ERIC Educational Resources Information Center

    Franklin, Cheryl

    2007-01-01

    The purpose of this quantitative study was to examine the ways elementary teachers use computer technology for instructional purposes and the factors that influence their use of computers. The population consisted of recent graduates from the elementary teacher preparation program at a mid-Atlantic university. Data were gathered using a survey…

  7. Some Factors Influencing Air Force Simulator Training Effectiveness. Technical Report.

    ERIC Educational Resources Information Center

    Caro, Paul W.

    A study of U.S. Air Force simulator training was conducted to identify factors that influence the effectiveness of such training and to learn how its effectiveness is being determined. The research consisted of a survey of ten representative Air Force simulator training programs and a review of the simulator training research literature. A number…

  8. Transcription factors as master regulator for cancer stemness: remove milk from fox?

    PubMed

    Nakano, Ichiro

    2014-08-01

    Some cancers display a cellular hierarchy of varying differentiation states, as if they phenocopy the normal organ development processes. Accumulating evidence suggests that the molecular signals that control carcinogenesis, at least partially, overlap with those involved in organogenesis. Cancer stem cells (CSCs) at the apex of cellular hierarchy are likely one, if not the only, critical therapeutic target in cancers. The proto-oncogene FOXM1 is a transcription factor (TF) defined as a master regulator for a broad array of genes required for CSCs and therefore FOXM1 is overexpressed in various cancers. In general, therapeutic development for TFs is a challenging task. Recently, on the other hand, novel insight has been brought by the discovery of a protein complex of FOXM1 with the mitotic kinase MELK in CSCs in brain cancers, as this protein complex appears to be cancer-specific. This editorial describes FOXM1 signaling in cancers and its potential therapeutic development. PMID:25017123

  9. An investigation of factors influencing accountability and performance ratings.

    PubMed

    Roch, Sylvia G; McNall, Laurel A

    2007-09-01

    The authors explored whether accountability has implications for performance ratings and investigated factors that may influence both accountability and performance ratings. Specifically, they investigated (a) whether feelings of accountability are directly related to performance ratings, (b) whether experimental manipulations that have been proposed to manipulate accountability in fact do so, and (c) the role of motivation-related constructs. They developed and tested a model of factors proposed to influence accountability and performance ratings. Results from 334 raters in an upward feedback situation in a classroom context provide empirical support that feelings of accountability influence rating level, as do perceptions of anonymity and the importance raters place on their jobs. However, neither anonymity nor importance perceptions were related to feelings of accountability. PMID:17933404

  10. The Influence Factors and Mechanism of Societal Risk Perception

    NASA Astrophysics Data System (ADS)

    Zheng, Rui; Shi, Kan; Li, Shu

    Risk perception is one of important subjects in management psychology and cognitive psychology. It is of great value in the theory and practice to investigate the societal hazards that the public cares a lot especially in Socio-economic transition period. A survey including 30 hazards and 6 risk attributes was designed and distributed to about 2, 485 residents of 8 districts, Beijing. The major findings are listed as following: Firstly, a scale of societal risk perception was designed and 2 factors were identified (Dread Risk & Unknown Risk). Secondly, structural equation model was used to analyze the influence factors and mechanism of societal risk perception. Risk preference, government support and social justice could influence societal risk perception directly. Government support fully moderated the relationship between government trust and societal risk perception. Societal risk perception influenced life satisfaction, public policy preferences and social development belief.

  11. Factors Influencing Renewable Energy Production & Supply - A Global Analysis

    NASA Astrophysics Data System (ADS)

    Ali, Anika; Saqlawi, Juman Al

    2016-04-01

    Renewable energy is one of the key technologies through which the energy needs of the future can be met in a sustainable and carbon-neutral manner. Increasing the share of renewable energy in the total energy mix of each country is therefore a critical need. While different countries have approached this in different ways, there are some common aspects which influence the pace and effectiveness of renewable energy incorporation. This presentation looks at data and information from 34 selected countries, analyses the patterns, compares the different parameters and identifies the common factors which positively influence renewable energy incorporation. The most successful countries are analysed for their renewable energy performance against their GDP, policy/regulatory initiatives in the field of renewables, landmass, climatic conditions and population to identify the most influencing factors to bring about positive change in renewable energy share.

  12. Factors influencing the international spread of equine diseases.

    PubMed

    Timoney, P J

    2000-12-01

    In an era of increasing globalization, the risk of spread of infectious diseases in humans and animals, including equids, has never been greater. International movement of equids and trade in semen are the most important factors responsible for the dissemination of various equine pathogens. Other factors that can or do have the potential to influence the global distribution of equine infectious diseases include: multinational trade agreements, emergent diseases, mutation of pathogens, climate related phenomena, migration of amplifying/reservoir hosts or vectors, availability of new vectors, vaccine contamination and agroterrorism. The relative importance of each of these factors is considered in relation to the spread of equine diseases. PMID:11219348

  13. The Bedouin Infant Feeding Study: study design and factors influencing the duration of breast feeding.

    PubMed

    Naggan, L; Forman, M R; Sarov, B; Lewando-Hundt, G; Zangwill, L; Chang, D; Berendes, H W

    1991-10-01

    A longitudinal study of infant feeding practices, growth and morbidity among Bedouin Arab infants residing in the Negev, Israel, was conducted during a 3-year period (1981-1983). Follow-up samples were restricted to healthy newborns. The majority of newborns are breast fed at birth but, by 2 months, 50% are also introduced to a milk supplement. Based on the bivariate analysis using the logrank test to examine the factors associated with exclusive versus partial breast feeding during the first 6 months, those born during the wet cool months are exclusively breast fed longer than those born during the dry season. More traditional women, living in tents rather than houses or huts, exclusively breast feed for at least 6 months. In a multiple logistic regression model, parity, house type and birth season are independently associated with the odds of exclusively breast feeding for the first 6 months of life. Factors influencing the duration of any breast feeding for the first 18 months include: house type, place of residence, birthweight, and whether the infant was stunted at 6 months. PMID:1754502

  14. A Review of Factors Influencing Athletes' Food Choices.

    PubMed

    Birkenhead, Karen L; Slater, Gary

    2015-11-01

    Athletes make food choices on a daily basis that can affect both health and performance. A well planned nutrition strategy that includes the careful timing and selection of appropriate foods and fluids helps to maximize training adaptations and, thus, should be an integral part of the athlete's training programme. Factors that motivate food selection include taste, convenience, nutrition knowledge and beliefs. Food choice is also influenced by physiological, social, psychological and economic factors and varies both within and between individuals and populations. This review highlights the multidimensional nature of food choice and the depth of previous research investigating eating behaviours. Despite numerous studies with general populations, little exploration has been carried out with athletes, yet the energy demands of sport typically require individuals to make more frequent and/or appropriate food choices. While factors that are important to general populations also apply to athletes, it seems likely, given the competitive demands of sport, that performance would be an important factor influencing food choice. It is unclear if athletes place the same degree of importance on these factors or how food choice is influenced by involvement in sport. There is a clear need for further research exploring the food choice motives of athletes, preferably in conjunction with research investigating dietary intake to establish if intent translates into practice. PMID:26243016

  15. Influence of Condensed Tannins from Ficus bengalensis Leaves on Feed Utilization, Milk Production and Antioxidant Status of Crossbred Cows.

    PubMed

    Dey, Avijit; De, Partha Sarathi

    2014-03-01

    This study was conducted to examine the effects of condensed tannins (CT) from Ficus bengalensis leaves on the feed utilization, milk production and health status of crossbred cows. Eighteen crossbred dairy cows at their second and mid lactation (avg. BW 351.6±10.6 kg) were randomly divided into two groups of nine each in a completely randomized block design and fed two iso-nitrogenous supplements formulated to contain 0% and 1.5% CT through dried and ground leaves of Ficus bengalensis. The diets were designated as CON and FBLM, respectively and fed to cows with a basal diet of rice straw to meet requirements for maintenance and milk production. The daily milk yield was significantly (p<0.05) increased due to supplementation of FBLM diet. The 4% fat corrected milk yield was also significantly (p<0.01) higher due to increased (p<0.05) milk fat in cows under diet FBLM as compared to CON. The inclusion of CT at 1.5% in the supplement did not interfere with the feed intake or digestibility of DM, OM, CP, EE, NDF, and ADF by lactating cows. Digestible crude protein (DCP) and total digestible nutrients (TDN) values of the composite diets were comparable between the groups. The blood biochemical parameters remained unaltered except significantly (p<0.05) lowered serum urea concentration in cows fed FBLM diet. There was a significant (p<0.05) increase intracellular reduced glutathione (GSH), superoxide dismutase (SOD) and catalase (CAT) activity in cows supplemented with condensed tannins. The total thiol group (T-SH) was found to be higher with reduction in lipid peroxidation (LPO) in cows of FBLM group. The cost of feeding per kg milk production was also reduced due to supplementation of Ficus bengalensis leaves. Therefore, a perceptible positive impact was evident on milk production and antioxidant status in crossbred cows during mid-lactation given supplement containing 1.5% CT through Ficus bengalensis leaves. PMID:25049960

  16. Influence of Condensed Tannins from Ficus bengalensis Leaves on Feed Utilization, Milk Production and Antioxidant Status of Crossbred Cows

    PubMed Central

    Dey, Avijit; De, Partha Sarathi

    2014-01-01

    This study was conducted to examine the effects of condensed tannins (CT) from Ficus bengalensis leaves on the feed utilization, milk production and health status of crossbred cows. Eighteen crossbred dairy cows at their second and mid lactation (avg. BW 351.6±10.6 kg) were randomly divided into two groups of nine each in a completely randomized block design and fed two iso-nitrogenous supplements formulated to contain 0% and 1.5% CT through dried and ground leaves of Ficus bengalensis. The diets were designated as CON and FBLM, respectively and fed to cows with a basal diet of rice straw to meet requirements for maintenance and milk production. The daily milk yield was significantly (p<0.05) increased due to supplementation of FBLM diet. The 4% fat corrected milk yield was also significantly (p<0.01) higher due to increased (p<0.05) milk fat in cows under diet FBLM as compared to CON. The inclusion of CT at 1.5% in the supplement did not interfere with the feed intake or digestibility of DM, OM, CP, EE, NDF, and ADF by lactating cows. Digestible crude protein (DCP) and total digestible nutrients (TDN) values of the composite diets were comparable between the groups. The blood biochemical parameters remained unaltered except significantly (p<0.05) lowered serum urea concentration in cows fed FBLM diet. There was a significant (p<0.05) increase intracellular reduced glutathione (GSH), superoxide dismutase (SOD) and catalase (CAT) activity in cows supplemented with condensed tannins. The total thiol group (T-SH) was found to be higher with reduction in lipid peroxidation (LPO) in cows of FBLM group. The cost of feeding per kg milk production was also reduced due to supplementation of Ficus bengalensis leaves. Therefore, a perceptible positive impact was evident on milk production and antioxidant status in crossbred cows during mid-lactation given supplement containing 1.5% CT through Ficus bengalensis leaves. PMID:25049960

  17. Consumer's Online Shopping Influence Factors and Decision-Making Model

    NASA Astrophysics Data System (ADS)

    Yan, Xiangbin; Dai, Shiliang

    Previous research on online consumer behavior has mostly been confined to the perceived risk which is used to explain those barriers for purchasing online. However, perceived benefit is another important factor which influences consumers’ decision when shopping online. As a result, an integrated consumer online shopping decision-making model is developed which contains three elements—Consumer, Product, and Web Site. This model proposed relative factors which influence the consumers’ intention during the online shopping progress, and divided them into two different dimensions—mentally level and material level. We tested those factors with surveys, from both online volunteers and offline paper surveys with more than 200 samples. With the help of SEM, the experimental results show that the proposed model and method can be used to analyze consumer’s online shopping decision-making process effectively.

  18. Variance of indoor radon concentration: Major influencing factors.

    PubMed

    Yarmoshenko, I; Vasilyev, A; Malinovsky, G; Bossew, P; Žunić, Z S; Onischenko, A; Zhukovsky, M

    2016-01-15

    Variance of radon concentration in dwelling atmosphere is analysed with regard to geogenic and anthropogenic influencing factors. Analysis includes review of 81 national and regional indoor radon surveys with varying sampling pattern, sample size and duration of measurements and detailed consideration of two regional surveys (Sverdlovsk oblast, Russia and Niška Banja, Serbia). The analysis of the geometric standard deviation revealed that main factors influencing the dispersion of indoor radon concentration over the territory are as follows: area of territory, sample size, characteristics of measurements technique, the radon geogenic potential, building construction characteristics and living habits. As shown for Sverdlovsk oblast and Niška Banja town the dispersion as quantified by GSD is reduced by restricting to certain levels of control factors. Application of the developed approach to characterization of the world population radon exposure is discussed. PMID:26409145

  19. Does supplementation of beef calves by creep feeding systems influence milk production and body condition of the dams?

    PubMed

    Lopes, Sidnei Antônio; Paulino, Mário Fonseca; Detmann, Edenio; Valente, Ériton Egídio Lisboa; de Barros, Lívia Vieira; Rennó, Luciana Navajas; de Campos Valadares Filho, Sebastião; Martins, Leandro Soares

    2016-08-01

    The aim of this study was to evaluate the effects of beef calves' supplementation in creep feeding systems on milk yield, body weight (BW), and body condition score (BCS) of their dams on tropical pastures using a meta-analytical approach. The database was obtained from 11 experiments conducted between 2009 and 2014 in Brazil, totaling 485 observations (cows). The database consisted of 273 Nellore and 212 crossbred (7/8 Nellore × 1/8 Holstein) cows. All experiments were carried out in the suckling phase (from 3 to 8 months of age of calves) during the transition phase between rainy and dry seasons from February to June of different years. The data were analyzed by a meta-analytical approach using mixed models and taking into account random variation among experiments. Calves' supplementation (P ≥ 0.59) and the calves' sex (P ≥ 0.48) did not affect milk yield of cows. The average fat-corrected milk (FCM) yield was 6.71 and 6.83 kg/day for cows that had their calves supplemented and not supplemented, respectively. Differences were observed (P < 0.0001) for milk yield due to the genetic group where crossbred cows presented greater FCM yield (7.37 kg/day) compared with Nellore cows (6.17 kg/day). There was no effect of the calves' supplementation on BW change (P ≥ 0.11) and BCS change (P ≥ 0.23) of the cows. Therefore, it is concluded that supplementation of beef calves using creep feeding systems in tropical pastures does not affect milk yield, body weight, or body condition of their dams. PMID:27193314

  20. Phenotypic, antimicrobial susceptibility profile and virulence factors of Klebsiella pneumoniae isolated from buffalo and cow mastitic milk

    PubMed Central

    Osman, Kamelia M; Hassan, Hany M; Orabi, Ahmed; Abdelhafez, Ahmed S T

    2014-01-01

    Studies on the prevalence and virulence genes of Klebsiella mastitis pathogens in a buffalo population are undocumented. Also, the association of rmpA kfu, uge, magA, Aerobactin, K1 and K2 virulent factors with K. pneumoniae buffalo, and cow mastitis is unreported. The virulence of K. pneumoniae was evaluated through both phenotypic and molecular assays. In vivo virulence was assessed by the Vero cell cytotoxicity, suckling mouse assay and mice lethality test. Antimicrobial susceptibility was tested by disk diffusion method. The 45 K. pneumoniae isolates from buffalo (n = 10/232) and cow (n = 35/293) milk were isolated (45/525; 8.6%) and screened via PCR for seven virulence genes encoding uridine diphosphate galactose 4 epimerase encoding gene responsible for capsule and smooth lipopolysaccharide synthesis (uge), siderophores (kfu and aerobactin), protectines or invasins (rmpA and magA), and the capsule and hypermucoviscosity (K1 and K2). The most common virulence genes were rmpA, kfu, uge, and magA (77.8% each). Aerobactin and K1 genes were found at medium rates of 66.7% each and K2 (55.6%). The Vero cell cytotoxicity and LD (50) in mice were found in 100% of isolates. A multidrug resistance pattern was observed for 40% of the antimicrobials. The distribution of virulence profiles indicate a role of rmpA, kfu, uge, magA, Aerobactin, and K1 and K2 in pathogenicity of K. pneumoniae in udder infections and invasiveness, and constitutes a threat for vulnerable animals, even more if they are in combination with antibiotic resistance. PMID:24915048

  1. Milk Fever Control Principles: A Review

    PubMed Central

    2002-01-01

    Three main preventive principles against milk fever were evaluated in this literature review, and the efficacy of each principle was estimated from the results of controlled investigations. Oral calcium drenching around calving apparently has a mean efficacy of 50%–60% in terms of milk fever prevention as well as prevention of milk fever relapse after intravenous treatment with calcium solutions. However, some drenches have been shown to cause lesions in the forestomacs. When using the DCAD (dietary cation-anion difference) principle, feeding rations with a negative DCAD (measured as (Na + K) – (Cl + S)) significantly reduce the milk fever incidence. Calculating the relative risk (RR) of developing milk fever from controlled experiments results in a mean RR between 0.19 and 0.35 when rations with a negative versus positive DCAD are compared. The main drawback from the DCAD principle is a palatability problem. The principle of feeding rations low in calcium is highly efficient in milk fever prevention provided the calcium intake in the dry period is kept below 20 g per day. Calculating the relative risk (RR) of developing milk fever from controlled experiments results in a very low mean RR (between 0 and 0.20) (daily calcium intake below versus above 20 g/d). The main problem in implementing the low-Ca principle is difficulties in formulating rations sufficiently low in calcium when using commonly available feeds. The use of large doses of vitamin D metabolites and analogues for milk fever prevention is controversial. Due to toxicity problems and an almost total lack of recent studies on the subject this principle is not described in detail. A few management related issues were discussed briefly, and the following conclusions were made: It is important to supply the periparturient cow with sufficient magnesium to fulfil its needs, and to prevent the dry cows from being too fat. Available information on the influence of carbohydrate intake, and on the effect of

  2. FACTORS INFLUENCING THE DESIGN OF BIOACCUMULATION FACTOR AND BIOTA-SEDIMENT ACCUMULATION FACTOR FIELD STUDIES

    EPA Science Inventory

    General guidance for designing field studies to measure bioaccumulation factors (BAFs) and biota-sediment accumulation factors (BSAFs) is not available. To develop such guidance, a series of modeling simulations were performed to evaluate the underlying factors and principles th...

  3. Factors influencing autism spectrum disorder screening by community paediatricians

    PubMed Central

    WS, Angie; Zwaigenbaum, Lonnie; Nicholas, David; Sharon, Raphael

    2015-01-01

    BACKGROUND: In most cases, autism spectrum disorders (ASD) can be reliably diagnosed at two to three years of age. However, Canadian data reveal a median age at diagnosis of approximately four years. OBJECTIVE: To examine general paediatricians’ practices regarding ASD screening and identify factors that influence decisions regarding the use of ASD screening tools. METHODS: Using a qualitative inquiry-based interpretive description approach, 12 paediatricians from four practice groups participated in four focus groups and one individual interview. These were conducted using semistructured interviews, digitally recorded and transcribed verbatim. RESULTS: Five main domains of themes were identified related to screening tool use: benefits; needs not addressed; elements that limit utility; elements that encourage utility; and implementation challenges. Factors influencing practice included availability of time, comfort with screening tool use, previous use and knowledge about specific tools. Systemic factors included knowledge and access to community resources, as well as the ability to provide support to the child and family. CONCLUSION: The results from the present study identified important factors that influence paediatric practice in ASD screening. As screening tools improve, it will be important to examine the implementation and effectiveness of screening tools and strategies for increased uptake. Future research will also need to attend to the practical needs of physicians and communities in the aim of earlier diagnosis and rapid access to interventional resources. PMID:26175565

  4. Human Milk: Mother Nature’s Prototypical Probiotic Food?1234

    PubMed Central

    McGuire, Michelle K; McGuire, Mark A

    2015-01-01

    The concept of “probiotic” is generally attributed to Dr. Ilya Mechnikov, who hypothesized that longevity could be enhanced by manipulating gastrointestinal microbes using naturally fermented foods. In 2001, a report of the FAO and WHO (2001 Oct, http://www.who.int/foodsafety/publications/fs_-management/en/probiotics.pdf) proposed a more restrictive definition of probiotic, as follows: “a live micro-organism which, when administered in adequate amounts, confers a health benefit on the host.” As such, answering the fundamental question posed here—“Is human milk a probiotic?”—requires first grappling with the concept and meaning of the term probiotic. Nonetheless, one must also be convinced that human milk contains bacteria. Indeed, there are scores of publications providing evidence of a paradigm shift in this regard. Variation in the human-milk microbiome may be associated with maternal weight, mode of delivery, lactation state, gestation age, antibiotic use, and maternal health. Milk constituents (e.g., fatty acids and complex carbohydrates) might also be related to the abundance of specific bacterial taxa in milk. Whether these bacteria affect infant health is likely, but more studies are needed to test this hypothesis. In summary, a growing literature suggests that human milk, like all other fluids produced by the body, indeed contains viable bacteria. As such, and recognizing the extensive literature relating breastfeeding to optimal infant health, we propose that human milk should be considered a probiotic food. Determining factors that influence which bacteria are present in milk and if and how they influence the mother’s and/or the recipient infant’s health remain basic science and public health realms in which almost nothing is known. PMID:25593150

  5. Milk lipids

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Milk fat conveys a number of desirable qualities to food, and various lipid components contribute to human nutrition and health. Over 96% of milk lipids consist of triacylglycerols, which contain a variety of fatty acids. Di- and monoacylglycerols, free fatty acids, sterols, and phospho-, glyco-,...

  6. Designer milk.

    PubMed

    Sabikhi, Latha

    2007-01-01

    Dairy biotechnology is fast gaining ground in the area of altering milk composition for processing and/or animal and human health by employing nutritional and genetic approaches. Modification of the primary structure of casein, alteration in the lipid profile, increased protein recovery, milk containing nutraceuticals, and replacement for infant formula offer several advantages in the area of processing. Less fat in milk, altered fatty acid profiles to include more healthy fatty acids such as CLA and omega-fats, improved amino acid profiles, more protein, less lactose, and absence of beta-lactoglobulin (beta-LG) are some opportunities of "designing" milk for human health benefits. Transgenic technology has also produced farm animals that secrete in their milk, human lactoferrin, lysozyme, and lipase so as to simulate human milk in terms of quality and quantity of these elements that are protective to infants. Cow milk allergenicity in children could be reduced by eliminating the beta-LG gene from bovines. Animals that produce milk containing therapeutic agents such as insulin, plasma proteins, drugs, and vaccines for human health have been genetically engineered. In order to cater to animal health, transgenic animals that express in their mammary glands, various components that work against mastitis have been generated. The ultimate acceptability of the "designer" products will depend on ethical issues such as animal welfare and safety, besides better health benefits and increased profitability of products manufactured by the novel techniques. PMID:17900499

  7. Effect of commercial grape extracts on the cheese-making properties of milk.

    PubMed

    Felix da Silva, Denise; Matumoto-Pintro, Paula T; Bazinet, Laurent; Couillard, Charles; Britten, Michel

    2015-03-01

    Grape extracts can be added to milk to produce cheese with a high concentration of polyphenols. Four commercial extracts from whole grape, grape seed, and grape skin (2 extracts) were characterized and added to milk at concentrations of 0, 0.1, 0.2, and 0.3% (wt/vol). The effect of grape extracts on the kinetics of milk clotting, milk gel texture, and syneresis were determined, and model cheeses were produced. Whole grape and grape seed extracts contained a similar concentration of polyphenolic compounds and about twice the amount found in grape skin extracts. Radical scavenging activity was directly proportional to the phenolic compounds content. When added to milk, grape extracts increased rennet-induced clotting time and decreased the clotting rate. Although differences were observed between the extracts, the concentration added to milk was the main factor influencing clotting properties. With increasing concentrations of grape extracts, milk gels showed increased brittleness and reduced firmness. In addition, syneresis of milk gels decreased with increasing concentrations of grape extracts, which resulted in cheeses with a higher moisture content. The presence of grape extracts in milk slightly increased protein recovery in cheese but had no effect on fat recovery. With whole grape or grape seed extracts added to milk at 0.1% (wt/vol), the recovery coefficient for polyphenols was about 0.63, and decreased with increasing extract concentration in milk. Better polyphenol recovery was observed for grape seed extracts (0.87), with no concentration effect. Commercial extracts from whole grape, grape seed, or grape skin can be added to milk in the 0.1 to 0.3% (wt/vol) concentration range to produce cheese with potential health benefits, without a negative effect on cheese yield. PMID:25597978

  8. The Influence of Contextual and Psychosocial Factors on Handwashing.

    PubMed

    Seimetz, Elisabeth; Boyayo, Anne-Marie; Mosler, Hans-Joachim

    2016-06-01

    Even though washing hands with soap is among the most effective measures to reduce the risk of infection, handwashing rates in infrastructure-restricted settings remain seriously low. Little is known about how context alone and in interaction with psychosocial factors influence hand hygiene behavior. The aim of this article was to explore how both contextual and psychosocial factors affect handwashing practices. A cross-sectional survey was conducted with 660 caregivers of primary school children in rural Burundi. Hierarchical regression analyses revealed that household wealth, the amount of water per person, and having a designated place for washing hands were contextual factors significantly predicting handwashing frequency, whereas the contextual factors, time spent collecting water and amount of money spent on soap, were not significant predictors. The contextual factors explained about 13% of the variance of reported handwashing frequency. The addition of the psychosocial factors to the regression model resulted in a significant 41% increase of explained variation in handwashing frequency. In this final model, the amount of water was the only contextual factor that remained a significant predictor. The most important predictors were a belief of self-efficacy, planning how, when, and where to wash hands, and always remembering to do so. The findings suggest that contextual constraints might be perceived rather than actual barriers and highlight the role of psychosocial factors in understanding hygiene behaviors. PMID:27139449

  9. Succesful Lean Manufacturing Implementation: Internal Key Influencing Factors

    NASA Astrophysics Data System (ADS)

    Virginia, Iuga; Claudiu, Kifor

    2015-09-01

    Manufacturing sectors and companies all over the world are successfully implementing lean principles within their processes. Nowadays, lean has become an indispensable part of global players. Companies worldwide need to be aware of multiple factors which weigh heavily on the success or failure of lean implementation. This paper focuses on giving a brief and structured overview over the fundamental organizational factors which play a substantial role for the lean manufacturing (LM) implementation process. The study below focuses on internal factors which are indispensable for a successful LM implementation within organizations. It is imperative that these internal factors are known, recognized and taken into consideration during the whole LM implementation process. Ignoring their influence on the process's implementation may lead to endangering the expected results or to making the process more difficult which could result in much higher human resource consumption.

  10. Factors Influencing Prolonged ICU Stay After Open Heart Surgery

    PubMed Central

    Azarfarin, Rasoul; Ashouri, Nasibeh; Totonchi, Ziae; Bakhshandeh, Hooman; Yaghoubi, Alireza

    2014-01-01

    Background: There are different risk factors that affect the intensive care unit (ICU) stay after cardiac surgery. Objectives: The aim of this study was to evaluate possible risk factors influencing prolonged ICU stay in a large referral hospital. Patients and Methods: We conducted a case-control study to determinate causes of prolonged ICU stay in 280 adult patients undergoing cardiac surgery in a tertiary care center for cardiovascular patients, Tehran, Iran. These patients were divided into two groups according to ICU stay ≤ 96 and > 96 hours. We evaluated perioperative risk factors of ICU stay > 96 hours. Results: Among the 280 patients studied, 184 (65.7%) had stayed ≤ 96 hours and 96 (34.3%) had stayed > 96 hours in ICU. Frequency of prolonged ICU stay was 34.2% in patients undergoing coronary artery bypass graft (CABG), 30.8% in patients with valve surgery, and 44.8% in patients with CABG plus valve surgery. Patients with > 96 hours of ICU stay received more blood transfusion and intravenous inotropes. They also had longer anesthesia, cardiopulmonary bypass, and postoperative intubation time. There were higher incidence of postoperative tamponade, re-exploration, re-intubation, hemodialysis, and hypotension in this group (P < 0.05 for all comparisons). Conclusions: In this study, about one-third of patients had prolonged ICU stay. Factors influencing prolonged ICU stay were medical and some non-medical factors. In the present study, up to 30% of the patients had a prolonged ICU stay of > 96 hours. Additional data from well-designed investigations are needed for further assessment of the factors influencing prolonged ICU stay after cardiac surgery. PMID:25785249

  11. Rapid identification of adulterated cow milk by non-linear pattern recognition methods based on near infrared spectroscopy.

    PubMed

    Zhang, Li-Guo; Zhang, Xin; Ni, Li-Jun; Xue, Zhi-Bin; Gu, Xin; Huang, Shi-Xin

    2014-02-15

    More than 800 representative milk samples, which consisted of 287 raw cow milk samples from different pastures surrounding Shanghai of China and 526 adulteration milk samples containing different pseudo proteins and thickeners, were collected and designed to demonstrate a method for rapidly discriminating adulterated milks based on near infrared (NIR) spectra. The NIR classification models were built by two non-linear supervised pattern recognition methods of improved support vector machine (I-SVM) and improved and simplified K nearest neighbours (IS-KNN). Uniform design theory was applied to optimize the parameters of SVM and thus the computation amount was reduced 90%. Both two methods exhibit good adaptability in discriminating adulterated milks from raw cow milks. Further investigation showed that the correction ratio for discriminating milk samples increased with the increasing of adulteration solutions' level in the adulterated milk. The concentration of adulterants is an important factor of influencing milk discrimination results of the NIR pattern recognition models. The results demonstrated the usefulness of NIR spectra combined with non-linear pattern recognition methods as an objective and rapid method for the authentication of complicated raw cow milks. PMID:24128487

  12. Health Related Quality of Life and Influencing Factors among Welders

    PubMed Central

    Qin, Jingxiang; Liu, Wuzhong; Zhu, Jun; Weng, Wei; Xu, Jiaming; Ai, Zisheng

    2014-01-01

    Background Occupational exposure to welding fumes is a serious occupational health problem all over the world. Welders are exposed to many occupational hazards; these hazards might cause some occupational diseases. The aim of the study was to assess the health related quality of life (HRQL) of electric welders in Shanghai China and explore influencing factors to HRQL of welders. Methods 301 male welders (without pneumoconiosis) and 305 non-dust male workers in Shanghai were enrolled in this study. Short Form-36 (SF-36) health survey questionnaires were applied in this cross-sectional study. Socio-demographic, working and health factors were also collected. Multiple stepwise regress analysis was used to identify significant factors related to the eight dimension scores. Results Six dimensions including role-physical (RP), bodily pain (BP), general health (GH), validity (VT), social function (SF), and mental health (MH) were significantly worse in welders compared to non-dust workers. Multiple stepwise regress analysis results show that native place, monthly income, quantity of children, drinking, sleep time, welding type, use of personal protective equipment (PPE), great events in life, and some symptoms including dizziness, discomfort of cervical vertebra, low back pain, cough and insomnia may be influencing factors for HRQL of welders. Among these factors, only sleep time and the use of PPE were salutary. Conclusions Some dimensions of HRQL of these welders have been affected. Enterprises which employ welders should take measures to protect the health of these people and improve their HRQL. PMID:25048102

  13. [Seasonal variation and related influencing factors for tuberculosis].

    PubMed

    Zhang, Z B; Lu, Z Q; Xie, H; Duan, Q H

    2016-08-10

    Tuberculosis is recognized as a chronic respiratory infectious disease and still one of the important public health issues in the world. Douglas reported an unique seasonal pattern (summer peak) of tuberculosis, when compared with most other respiratory diseases in 1996. Since then, there had been many other researchers notified various patterns of seasonality on TB. This paper reviewed all the studies published in the last five years and analyzed the current findings on seasonal variability and influencing factors, in order to explore the risk factors to provide evidence for prevention and control strategies on tuberculosis. PMID:27539356

  14. The Influence of Various Factors on the Methane Fermentation Process

    NASA Astrophysics Data System (ADS)

    Kurbanova, M. G.; Egushova, E. A.; Pozdnjakova, OG

    2015-09-01

    The article describes the stages of the methane fermentation process. The phases of methane formation are characterized. The results of the experimental data based on the study of various factors influencing the rate of biogas production and its yield are presented. Such factors as the size of the substrate particles and temperature conditions in the reactor are considered. It is revealed on the basis of experimental data which of the farm animals and poultry excrements are exposed to the most complete fermentation without special preparation. The relationship between fermentation regime, particle size of the feedstock and biogas yield is graphically presented.

  15. Children's disaster reactions: the influence of family and social factors.

    PubMed

    Pfefferbaum, Betty; Jacobs, Anne K; Houston, J Brian; Griffin, Natalie

    2015-07-01

    This review examines family (demographics, parent reactions and interactions, and parenting style) and social (remote effects, disaster media coverage, exposure to secondary adversities, and social support) factors that influence children's disaster reactions. Lower family socioeconomic status, high parental stress, poor parental coping, contact with media coverage, and exposure to secondary adversities have been associated with adverse outcomes. Social support may provide protection to children in the post-disaster environment though more research is needed to clarify the effects of certain forms of social support. The interaction of the factors described in this review with culture needs further exploration. PMID:25980512

  16. Environmental factors influencing the efficacy of probiotic bacteria.

    PubMed

    Marco, Maria L; Tachon, Sybille

    2013-04-01

    Probiotic bacteria are not typical ingredients but rather living cells that can rapidly respond and adapt to changing conditions in their environment. Numerous factors from culture preparation and preservation, conditions in consumer product matrices, and genetic, dietary, cultural, and health differences between consumers can affect probiotic cell activity and probably influence the specific host-microbe interactions required for probiotic effects in the digestive tract. Understanding the impact of these factors on probiotic efficacy will aid in elucidating the molecular mechanisms of probiotic function, improve the design of probiotic-containing consumer products, and guide the establishment of standardized procedures for clinical studies intended to evaluate probiotic effects. PMID:23102489

  17. Metal Oxide Gas Sensors: Sensitivity and Influencing Factors

    PubMed Central

    Wang, Chengxiang; Yin, Longwei; Zhang, Luyuan; Xiang, Dong; Gao, Rui

    2010-01-01

    Conductometric semiconducting metal oxide gas sensors have been widely used and investigated in the detection of gases. Investigations have indicated that the gas sensing process is strongly related to surface reactions, so one of the important parameters of gas sensors, the sensitivity of the metal oxide based materials, will change with the factors influencing the surface reactions, such as chemical components, surface-modification and microstructures of sensing layers, temperature and humidity. In this brief review, attention will be focused on changes of sensitivity of conductometric semiconducting metal oxide gas sensors due to the five factors mentioned above. PMID:22294916

  18. Factors influencing the local planning of dental services.

    PubMed

    Downer, M C; Whittle, J G; Teagle, F A

    1979-10-01

    Findings from a survey of 796 high school children in four districts constituting a health administrative area were examined to ascertain the factors influencing their dental disease experience, treatment received and attendance pattern. In three of the four districts, over 60% of the children were regular attenders, enjoying the benefit of less active caries than irregular attenders. However, in the remaining district, much of which consisted of depressed, inner city areas undergoing re-development, only one third were regular attenders. Several local factors, such as availability and accessibility of services, probably influenced the numbers seeking regular care, but one of the most important appeared to be the level of provision in the salaried Community Dental Service. The implications of the findings for planning improvements in local services are discussed. PMID:295706

  19. Gender differences in how retirees perceive factors influencing unretirement.

    PubMed

    Armstrong-Stassen, Marjorie; Staats, Sara

    2012-01-01

    Returning to paid employment after retirement is occurring in many developed countries and can be expected to increase in the future. This study compared how women (n = 202) and men (n = 347) who had retired from a managerial or professional career occupation perceived factors associated with unretirement. Retired professional women perceived reasons to unretire, age-friendly human resource practices, and re-entry barriers to have greater influence on retirees' decision to unretire than retired managerial women and retired men. Both groups of retired women perceived training and development opportunities to have more influence than retired men. A major contribution of this study is the identification of pre-retirement career occupation as having an important effect on how female, but not male, retirees perceived the various factors. The findings suggest that researchers and employers need to consider the diversity that exists among retirees, not only gender differences but also differences among retired career women. PMID:23115913

  20. An Integrative Review of Factors Influencing Breastfeeding in Adolescent Mothers.

    PubMed

    Kanhadilok, Supannee; McGrath, Jacqueline M

    2015-01-01

    The purpose of this integrative review was to describe factors that influence breastfeeding behaviors in adolescent mothers. Twenty-two articles met inclusion criteria. Findings showed that most adolescent mothers intended to breastfeed during pregnancy. Yet, breastfeeding initiation ranged from 39% to 69%. Almost half of adolescent mothers stopped within 1 month. Less than 25% continued to breastfeeding behaviors to 6 months. Factors that influenced breastfeeding decisions in adolescent mothers included social and cultural norms. Personal beliefs about being a good mother were important to intention and initiation of breastfeeding. Promoting maternal competence was found to be essential to breastfeeding initiation and continuation for adolescent mothers. Support from partners and professionals also led to positive attitudes toward breastfeeding initiation and continuation. PMID:26957895

  1. An Integrative Review of Factors Influencing Breastfeeding in Adolescent Mothers

    PubMed Central

    Kanhadilok, Supannee; McGrath, Jacqueline M.

    2015-01-01

    ABSTRACT The purpose of this integrative review was to describe factors that influence breastfeeding behaviors in adolescent mothers. Twenty-two articles met inclusion criteria. Findings showed that most adolescent mothers intended to breastfeed during pregnancy. Yet, breastfeeding initiation ranged from 39% to 69%. Almost half of adolescent mothers stopped within 1 month. Less than 25% continued to breastfeeding behaviors to 6 months. Factors that influenced breastfeeding decisions in adolescent mothers included social and cultural norms. Personal beliefs about being a good mother were important to intention and initiation of breastfeeding. Promoting maternal competence was found to be essential to breastfeeding initiation and continuation for adolescent mothers. Support from partners and professionals also led to positive attitudes toward breastfeeding initiation and continuation. PMID:26957895

  2. Influence of organic diet on the amount of conjugated linoleic acids in breast milk of lactating women in the Netherlands.

    PubMed

    Rist, Lukas; Mueller, André; Barthel, Christiane; Snijders, Bianca; Jansen, Margje; Simões-Wüst, A Paula; Huber, Machteld; Kummeling, Ischa; von Mandach, Ursula; Steinhart, Hans; Thijs, Carel

    2007-04-01

    The aim of the present study was to find out whether the incorporation of organic dairy and meat products in the maternal diet affects the contents of the conjugated linoleic acid isomers (CLA) and trans-vaccenic acid (TVA) in human breast milk. To this purpose, milk samples from 312 breastfeeding mothers participating in the KOALA Birth Cohort Study have been analysed. The participants had documented varying lifestyles in relation to the use of conventional or organic products. Breast milk samples were collected 1 month postpartum and analysed for fatty acid composition. The content of rumenic acid (the main CLA) increased in a statistically significant way while going from a conventional diet (no organic dairy/meat products, 0.25 weight % (wt%), n 186) to a moderately organic diet (50-90 % organic dairy/meat, 0.29 wt%, n 33, P = 0.02) and to a strict organic diet (>90 % organic dairy/meat, 0.34 wt%, n 37, P milk can be modulated if breastfeeding mothers replace conventional dairy and/or meat products by organic ones. A potential contribution of CLA and TVA to health improvement is briefly discussed. PMID:17349086

  3. [Influencing factors in measuring absorption coefficient of suspended particulate matters].

    PubMed

    Yu, Xiao-long; Shen, Fang; Zhang, Jin-fang

    2013-05-01

    Absorption coefficient of suspended particulate matters in natural water is one of the key parameters in ocean color remote sensing. In order to study the influencing factors that affect the measurement, a series of experiments were designed to measure samples using transmittance method (T method), transmittance-reflectance method (T-R method) and absorptance method (A method). The results shows that absorption coefficient measured by the A method has a much lower error compared to the T method and T-R method due to influencing factors,such as filter-to-filter variations, water content of the filter, and homogeneity of filter load and so on. Another factor influence absorption coefficient is path-length amplification induced by multiple scattering inside the filter. To determine the path-length amplification, the true absorption was measured by AC-s (WetLabs). The linear fitting result shows that the mean path-length amplification is much higher for the A method than that of the T-R method and the T method (4.01 versus 2.20 and 2.32), and the corresponding correlation coefficient are 0.90, 0.87 and 0.80. For the A method and the T-R method, higher correlation coefficients are calculated when using polynomial fitting, and the value are 0.95 and 0.94. Analysis of the mean relative error caused by different influencing factors indicates that path-length amplification is the largest error source in measuring the absorption coefficient. PMID:23914523

  4. [Factors influencing development and progression of alcoholic liver disease].

    PubMed

    Abdelrahman, K; Marot, A; Deltenre, P

    2015-09-01

    Only a minority ot excessive drinkers develop cirrhosis. The main cofactors implicated in the pathophysiology of alcoholic liver disease are obesity, diabetes or the metabolic syndrome. Several genetic polymorphisms have been associated with a higher risk of alcoholic cirrhosis. Recent data indicate that gut microbiota could play a role in the pathogenesis of alcoholic liver disease. The aim of this review is to summarize the factors that influence development and progression of alcoholic liver disease. PMID:26502621

  5. Microbiological quality and somatic cell count in bulk milk of dromedary camels (Camelus dromedarius): descriptive statistics, correlations, and factors of variation.

    PubMed

    Nagy, P; Faye, B; Marko, O; Thomas, S; Wernery, U; Juhasz, J

    2013-09-01

    The objectives of the present study were to monitor the microbiological quality and somatic cell count (SCC) of bulk tank milk at the world's first large-scale camel dairy farm for a 2-yr period, to compare the results of 2 methods for the enumeration of SCC, to evaluate correlation among milk quality indicators, and to determine the effect of specific factors (year, season, stage of lactation, and level of production) on milk quality indicators. The study was conducted from January 2008 to January 2010. Total viable count (TVC), coliform count (CC), California Mastitis Test (CMT) score, and SCC were determined from daily bulk milk samples. Somatic cell count was measured by using a direct microscopic method and with an automatic cell counter. In addition, production parameters [total daily milk production (TDM, kg), number of milking camels (NMC), average milk per camel (AMC, kg)] and stage of lactation (average postpartum days, PPD) were recorded for each test day. A strong correlation (r=0.33) was found between the 2 methods for SCC enumeration; however, values derived using the microscopic method were higher. The geometric means of SCC and TVC were 394×10(3) cells/mL and 5,157 cfu/mL during the observation period, respectively. Somatic cell count was >500×10(3) cells/mL on 14.6% (106/725) and TVC was >10×10(3) cfu/mL on 4.0% (30/742) of the test days. Both milk quality indicators had a distinct seasonal pattern. For log SCC, the mean was lowest in summer and highest in autumn. The seasonal pattern of log TVC was slightly different, with the lowest values being recorded during the spring. The monthly mean TVC pattern showed a clear difference between years. Coliform count was <10 cfu/mL in most of the samples (709/742, 95.6%). A positive correlation was found between log SCC and log TVC (r=0.32), between log SCC and CMT score (r=0.26), and between log TVC and CC in yr 1 (r=0.30). All production parameters and stage of lactation showed strong seasonal

  6. Correlation between precipitation and geographical location of the δ2H values of the fatty acids in milk and bulk milk powder

    NASA Astrophysics Data System (ADS)

    Ehtesham, E.; Baisden, W. T.; Keller, E. D.; Hayman, A. R.; Van Hale, R.; Frew, R. D.

    2013-06-01

    Hydrogen isotope ratios (δ2H) have become a tool for food traceability and authentication of agricultural products. The principle is that the isotopic composition of the produce is influenced by environmental and biological factors and hence exhibits a spatial differentiation of δ2H. This study investigates the variation in δ2H values of New Zealand milk, both in the bulk powder and individual fatty acids extracted from milk samples from dairy factories across New Zealand. Multivariate statistical analyses were used to test for relationships between δ2H of bulk milk powder, milk fatty acid and geographical location. Milk powder samples from different regions of New Zealand were found to exhibit patterns in isotopic composition similar to the corresponding regional precipitation associated with their origin. A model of δ2H in precipitation was developed based on measurements between 2007 and 2010 at 51 stations across New Zealand (Frew and Van Hale, 2011). The model uses multiple linear regressions to predict daily δ2H from 2 geographic and 5 rain-weighted climate variables from the 5 × 5 km New Zealand Virtual Climate Station Network (VCSN). To approximate collection radius for a drying facility the modelled values were aggregated within a 50 km radius of each dairy factory and compared to observed δ2H values of precipitation and bulk milk powder. Daily δ2H predictions for the period from August to December for the area surrounding the sample collection sites were highly correlated with the δ2H values of bulk milk powder. Therefore the δ2H value of milk fatty acids demonstrates promise as a tool for determining the provenance of milk powders and products where milk powder is an ingredient. Separation of milk powder origin to geographic sub-regions within New Zealand was achieved. Hydrogen isotope measurements could be used to complement traditional tracking systems in verifying point of origin.

  7. Factors influencing veterinary students career choices and attitudes to animals.

    PubMed

    Serpell, James A

    2005-01-01

    The purpose of the study was to investigate the influence of demographic and experiential factors on first-year veterinary students career choices and attitudes to animal welfare/rights. The study surveyed 329 first-year veterinary students to determine the influence of demographic factors, farm experience, and developmental exposure to different categories of animals on their career preferences and on their attitudes to specific areas of animal welfare and/or rights. A significant male gender bias toward food-animal practice was found, and prior experience with particular types of animals--companion animals, equines, food animals--tended to predict career preferences. Female veterinary students displayed greater concern for possible instances of animal suffering than males, and prior experience with different animals, as well as rural background and farm experience, were also associated with attitude differences. Seventy-two percent of students also reported that their interactions with animals (especially pets) had strongly influenced the development of their values. Animals ranked second in importance after parents in this respect. The present findings illustrate the importance to issues of animal welfare of the cultural context of past experience and influences on attitude development. The results also suggest that previous interactions with animals play a critical role in guiding veterinary students into their chosen career, as well as in helping to determine their specific employment preferences within the veterinary profession. From an animal welfare perspective, the dearth of women choosing careers in food-animal practice is a source of concern. PMID:16421833

  8. Research on Factors Influencing Individual's Behavior of Energy Management

    NASA Astrophysics Data System (ADS)

    Fan, Yanfeng

    With the rapid rise of distributed generation, Internet of Things, and mobile Internet, both U.S. and European smart home manufacturers have developed energy management solutions for individual usage. These applications help people manage their energy consumption more efficiently. Domestic manufacturers have also launched similar products. This paper focuses on the factors influencing Energy Management Behaviour (EMB) at the individual level. By reviewing academic literature, conducting surveys in Beijing, Shanghai and Guangzhou, the author builds an integrated behavioural energy management model of the Chinese energy consumers. This paper takes the vague term of EMB and redefines it as a function of two separate behavioural concepts: Energy Management Intention (EMI), and the traditional Energy Saving Intention (ESI). Secondly, the author conducts statistical analyses on these two behavioural concepts. EMI is the main driver behind an individual's EMB. EMI is affected by Behavioural Attitudes, Subjective Norms, and Perceived Behavioural Control (PBC). Among these three key factors, PBC exerts the strongest influence. This implies that the promotion of the energy management concept is mainly driven by good application user experience (UX). The traditional ESI also demonstrates positive influence on EMB, but its impact is weaker than the impacts arising under EMI's three factors. In other words, the government and manufacturers may not be able to change an individual's energy management behaviour if they rely solely on their traditional promotion strategies. In addition, the study finds that the government may achieve better promotional results by launching subsidies to the manufacturers of these kinds of applications and smart appliances.

  9. A real-time assessment of factors influencing medication events.

    PubMed

    Dollarhide, Adrian W; Rutledge, Thomas; Weinger, Matthew B; Fisher, Erin Stucky; Jain, Sonia; Wolfson, Tanya; Dresselhaus, Timothy R

    2014-01-01

    Reducing medical error is critical to improving the safety and quality of healthcare. Physician stress, fatigue, and excessive workload are performance-shaping factors (PSFs) that may influence medical events (actual administration errors and near misses), but direct relationships between these factors and patient safety have not been clearly defined. This study assessed the real-time influence of emotional stress, workload, and sleep deprivation on self-reported medication events by physicians in academic hospitals. During an 18-month study period, 185 physician participants working at four university-affiliated teaching hospitals reported medication events using a confidential reporting application on handheld computers. Emotional stress scores, perceived workload, patient case volume, clinical experience, total sleep, and demographic variables were also captured via the handheld computers. Medication event reports (n = 11) were then correlated with these demographic and PSFs. Medication events were associated with 36.1% higher perceived workload (p < .05), 38.6% higher inpatient caseloads (p < .01), and 55.9% higher emotional stress scores (p < .01). There was a trend for reported events to also be associated with less sleep (p = .10). These results confirm the effect of factors influencing medication events, and support attention to both provider and hospital environmental characteristics for improving patient safety. PMID:23551380

  10. Factors Potentially Influencing Student Acceptance of Biological Evolution

    NASA Astrophysics Data System (ADS)

    Wiles, Jason R.

    This investigation explored scientific, religious, and otherwise nonscientific factors that may influence student acceptance of biological evolution and related concepts, how students perceived these factors to have influenced their levels of acceptance of evolution and changes therein, and what patterns arose among students' articulations of how their levels of acceptance of evolution may have changed. This exploration also measured the extent to which students' levels of acceptance changed following a treatment designed to address factors identified as potentially affecting student acceptance of evolution. Acceptance of evolution was measured using the MATE instrument (Rutledge and Warden, 1999; Rutledge and Sadler, 2007) among participants enrolled in a secondary-level academic program during the summer prior to their final year of high school and as they transitioned to the post-secondary level. Student acceptance of evolution was measured to be significantly higher than pre-treatment levels both immediately following and slightly over one year after treatment. Qualitative data from informal questionnaires, from formal course evaluations, and from semi-structured interviews of students engaged in secondary level education and former students at various stages of post-secondary education confirmed that the suspected factors were perceived by participants to have influenced their levels of acceptance of evolution. Furthermore, participant reports provided insight regarding the relative effects they perceived these factors to have had on their evolution acceptance levels. Additionally, many participants reported that their science teachers in public schools had avoided, omitted, or denigrated evolution during instruction, and several of these students expressed frustration regarding what they perceived to have been a lack of education of an important scientific principle. Finally, no students expressed feelings of being offended by having been taught about

  11. Breeding Services and the Factors Influencing Their Use on Smallholder Dairy Farms in Central Uganda

    PubMed Central

    Kayiizi, Vincent; Owiny, David; Mburu, John

    2014-01-01

    Dairy cattle breeding is an important technology in the enhancement and promotion of dairy production in Uganda. The introduction of germplasm through AI is crucial to enhance the production potential of the local breeds. A study was conducted in six districts of Uganda in the central region using a questionnaire survey involving 450 randomly selected households to profile the dairy breeding services in use and investigate the factors that affect the success of dairy breeding focusing on AI. Adoption of the AI service was highly (P < 0.05) dependent on ava ilability of extension services, record keeping practice (P < 0.05), and availability of milk markets (P < 0.05). On the other hand AI adoption was independent of formal education, age of farmer, labor availability, and feed/water availability (P > 0.05). Use or nonuse of AI did not significantly (P > 0.05) influence the sex of the calf born. While preference for AI was marked, very few farmers actually used it. This implies that focus should be put on improved AI service delivery alongside improved extension services. PMID:24782940

  12. Trefoil factor 3 (TFF3) from human breast milk activates PAR-2 receptors, of the intestinal epithelial cells HT-29, regulating cytokines and defensins.

    PubMed

    Barrera, G J; Tortolero, G Sanchez

    2016-01-01

    Trefoil factors are effector molecules in gastrointestinal tract physiology. Each one improves healing of the gastrointestinal tract. Trefoil factors may be grouped into three classes: the gastric peptides (TFF1), spasmolytic peptide (TFF2) and intestinal trefoil factor (TFF3). Significant amounts of TFF3 are present in human breast milk. Previously, we have reported that trefoil factor 3 isolated from human breast milk produces down regulation of cytokines and promotes human beta defensins expression in intestinal epithelial cells. This study aimed to determine the molecular mechanism involved. Here we showed that the presence of TFF3 strongly correlated with protease activated receptors 2 (PAR-2) activation in human intestinal cells. Intracellular calcium ((Ca2+)i)mobilization was induced by the treatment with: 1) TFF3, 2) synthetic PAR-2 agonist peptide. The co-treatment with a synthetic PAR-2 antagonist peptide and TFF3 eliminates the latter's effect. Additionally, we demonstrated the existence of interactions among TFF3 and PAR-2 receptors through far Western blot and co-precipitation. Finally, down regulation of PAR-2 by siRNA resulted in a decrease of TFF3 induced intracellular (Ca2+)i mobilization, cytokine regulation and defensins expression. These findings suggest that TFF3 activates intestinal cells through PAR-2 (Fig. 4, Ref. 19). PMID:27546365

  13. Personal and situational factors influencing coaches' perceptions of stress.

    PubMed

    Knight, Camilla J; Reade, Ian L; Selzler, Anne-Marie; Rodgers, Wendy M

    2013-01-01

    Coaching has been recognised as a demanding occupation, associated with a range of stressors. The extent to which coaches perceive stress is likely to be influenced by various personal and situational factors. The purpose of this study was to identify coaches' levels of perceived stress and examine the personal and situational factors that may influence coaches' perceptions of stress. In total, 502 coaches working with university, college, Canada Games, and/or nationally identified athletes completed this study. Coaches completed an online survey, which included questions regarding demographics, work/job-related considerations, and aspects relating to their contract. Coaches also completed the Perceived Stress Scale (Cohen, Kamarck, & Mermelstein, 1983). Overall coaches indicated slightly below average levels of perceived stress (M = 15.13 out of 40) compared with norm-values (Cohen & Janicki-Deverts, 2012). Demographic factors, job-related characteristics, and certain aspects of their contract were associated with coaches' perceptions of stress. In particular, unclear expectations, long-working hours (>40), lack of agreed evaluation criteria, higher salaries, and a lack of social support were related to higher perceptions of stress. As such, the findings of the current study indicate that a reduction in perceived stress is likely to be achieved through a multifaceted approach that addresses multiple factors associated with coaching. PMID:23402372

  14. Factors influencing palliative care. Qualitative study of family physicians' practices.

    PubMed Central

    Brown, J. B.; Sangster, M.; Swift, J.

    1998-01-01

    OBJECTIVE: To examine factors that influence family physicians' decisions to practise palliative care. DESIGN: Qualitative method of in-depth interviews. SETTING: Southwestern Ontario. PARTICIPANTS: Family physicians who practise palliative care on a full-time basis, who practise on a part-time basis, or who have retired from active involvement in palliative care. METHOD: Eleven in-depth interviews were conducted to explore factors that influence family physicians' decisions to practise palliative care and factors that sustain their interest in palliative care. All interviews were audiotaped and transcribed verbatim. The analysis strategy used a phenomenological approach and occurred concurrently rather than sequentially. All interview transcriptions were read independently by the researchers, who then compared and combined their analyses. Final analysis involved examining all interviews collectively, thus permitting relationships between and among central themes to emerge. MAIN OUTCOME FINDINGS: The overriding theme was a common philosophy of palliative care focusing on acceptance of death, whole person care, compassion, communication, and teamwork. Participants' philosophies were shaped by their education and by professional and personal experiences. In addition, participants articulated personal and systemic factors currently affecting their practice of palliative care. CONCLUSIONS: Participants observed that primary care physicians should be responsible for their patients' palliative care within the context of interdisciplinary teams. For medical students to be knowledgeable and sensitive to the needs of dying patients, palliative care should be given higher priority in the curriculum. Finally, participants argued compellingly for transferring the philosophy of palliative care to the overall practice of medicine. PMID:9612588

  15. Factors influencing perceived sustainability of Dutch community health programs.

    PubMed

    Vermeer, A J M; Van Assema, P; Hesdahl, B; Harting, J; De Vries, N K

    2015-09-01

    We assessed the perceived sustainability of community health programs organized by local intersectoral coalitions, as well as the factors that collaborating partners think might influence sustainability. Semi-structured interviews were conducted among 31 collaborating partners of 5 community health programs in deprived neighborhoods in the southern part of the Netherlands. The interview guide was based on a conceptual framework that includes factors related to the context, the leading organization, leadership, the coalition, collaborating partners, interventions and outcomes. Interviews were recorded, transcribed and content analyzed using NVivo 8.0. Participants in each of the programs varied in their perceptions of the sustainability of the program, but those people collaborating in pre-existing neighborhood structures expressed relatively high faith in their continuation. The participating citizens in particular believed that these structures would continue to address the health of the community in the future. We found factors from all categories of the conceptual framework that were perceived to influence sustainability. The program leaders appeared to be crucial to the programs, as they were frequently mentioned in close interaction with other factors. Program leaders should use a motivating and supportive leadership style and should act as 'program champions'. PMID:24021354

  16. [INFLUENCE OF THE REGULAR INTAKE OF FERMENTED MILK PRODUCTS ENRICHED BY MICRONUTRIENTS ON SOME INDICES OF IRON METABOLISM IN ADOLESCENTS INVOLVED IN SPORTS].

    PubMed

    Turchaninov, D V; Bovarskaya, L A; Bogdashin, I V; Bagrova, L V; Gotwald, A R; Kozubenko, O V

    2015-01-01

    There was performed an experimental study of the influence of regular intake offermented milk enriched by products "Bifidin" and "Prolacta" on indices of iron metabolism in adolescents of 12-17 years, involved in sports (n = 94). In all study participants there was made double blood test (every 60 days), there were determined the levels of hemoglobin, serum iron, serum ferritin, C-reactive protein. The intervention in the main group (n = 68) was in daily intake offermented milk product in a volume of 200 ml (1 Cup) in addition to the normal diet within 2 months, including 35 cases who had used the bioproduct "Bifidin" and 33 persons- bioproduct "Prolacta". The control group was consisted of 26 persons from the adolescents engaged in the same sections, but not taking additional fermented milk drinks. The average values of all studied indices in adolescent athletes of the main and control groups before and after the intervention were consistent with reference values. Latent iron deficiency was detected in 23.4 ± 4.4% of adolescents involved in sports. At the second point of the research in two months of intake of enriched dairy products in the main group there was noticed the gain in levels of serum iron, ferritin, and the decline of the concentration of C-reactive protein. The results of the study allow us to consider enriched dairy products "Bifidin" and "Prolacta" as one of the components of complex measures of prophylaxis of hypovitaminosis and microelementoses in adolescents who are actively involved in sports. PMID:27029177

  17. Factors Influencing Learning Environments in an Integrated Experiential Program

    NASA Astrophysics Data System (ADS)

    Koci, Peter

    The research conducted for this dissertation examined the learning environment of a specific high school program that delivered the explicit curriculum through an integrated experiential manner, which utilized field and outdoor experiences. The program ran over one semester (five months) and it integrated the grade 10 British Columbian curriculum in five subjects. A mixed methods approach was employed to identify the students' perceptions and provide richer descriptions of their experiences related to their unique learning environment. Quantitative instruments were used to assess changes in students' perspectives of their learning environment, as well as other supporting factors including students' mindfulness, and behaviours towards the environment. Qualitative data collection included observations, open-ended questions, and impromptu interviews with the teacher. The qualitative data describe the factors and processes that influenced the learning environment and give a richer, deeper interpretation which complements the quantitative findings. The research results showed positive scores on all the quantitative measures conducted, and the qualitative data provided further insight into descriptions of learning environment constructs that the students perceived as most important. A major finding was that the group cohesion measure was perceived by students as the most important attribute of their preferred learning environment. A flow chart was developed to help the researcher conceptualize how the learning environment, learning process, and outcomes relate to one another in the studied program. This research attempts to explain through the consideration of this case study: how learning environments can influence behavioural change and how an interconnectedness among several factors in the learning process is influenced by the type of learning environment facilitated. Considerably more research is needed in this area to understand fully the complexity learning

  18. Factors influencing scores on the Social Responsiveness Scale

    PubMed Central

    Hus, Vanessa; Bishop, Somer; Gotham, Katherine; Huerta, Marisela; Lord, Catherine

    2012-01-01

    Background The Social Responsiveness Scale (SRS) is a parent-completed screening questionnaire often used to measure ASD severity. Although child characteristics are known to influence scores from other ASD-symptom measures, as well as parent-questionnaires more broadly, there has been limited consideration of how non-ASD-specific factors may affect interpretation of SRS scores. Previous studies have explored effects of behavior problems on SRS specificity, but have not addressed influences on the use of the SRS as a quantitative measure of ASD-symptoms. Method Raw scores (SRS-Raw) from parent-completed SRS were analyzed for 2,368 probands with ASD and 1,913 unaffected siblings. Regression analyses were used to assess associations between SRS scores and demographic, language, cognitive, and behavior measures. Results For probands, higher SRS-Raw were associated with greater non-ASD behavior problems, higher age, and more impaired language and cognitive skills, as well as scores from other parent report measures of social development and ASD-symptoms. For unaffected siblings, having more behavior problems predicted higher SRS-Raw; male gender, younger age and poorer adaptive social and expressive communication skills also showed small, but significant effects. Conclusions When using the SRS as a quantitative phenotype measure, the influence of behavior problems, age, and expressive language or cognitive level on scores must be considered. If effects of non-ASD-specific factors are not addressed, SRS scores are more appropriately interpreted as indicating general levels of impairment, than as severity of ASD-specific symptoms or social impairment. Further research is needed to consider how these factors influence the SRS’ sensitivity and specificity in large, clinical samples including individuals with disorders other than ASD. PMID:22823182

  19. Factors influencing Malaysian public attitudes to agro-biotechnology.

    PubMed

    Amin, Latifah; Ahmad, Jamil; Jahi, Jamaluddin Md; Nor, Abd Rahim Md; Osman, Mohamad; Mahadi, Nor Muhammad

    2011-09-01

    Despite considerable research in advanced countries on public perceptions of and attitudes to modern biotechnology, limited effort has been geared towards developing a structural model of public attitudes to modern biotechnology. The purpose of this paper is to identify the relevant factors influencing public attitudes towards genetically modified (GM) soybean, and to analyze the relationship between all the attitudinal factors. A survey was carried out on 1,017 respondents from various stakeholder groups in the Klang Valley region. Results of the survey have confirmed that attitudes towards complex issues such as biotechnology should be seen as a multifaceted process. The most important factors predicting support for GM soybean are the specific application-linked perceptions about the benefits, acceptance of risk and moral concern while risk and familiarity are significant predictors of benefit and risk acceptance. Attitudes towards GM soybean are also predicted by several general classes of attitude. PMID:22164706

  20. [Factors influencing self-perception of overweight people].

    PubMed

    Makara-Studzińska, Marta; Podstawka, Danuta; Goclon, Karolina

    2013-11-01

    Shaping of self-perception is among others influenced by physical, interpersonal, emotional, and cultural factors. In self-perception of overweight people an important role is played by interpersonal factors, which include the opinions of others and the relationship with the surrounding. The evaluation of the body image is also affect by sociocultural factors including the media, which create an unrealistic and impossible to achieve ideal of beauty. Contemporary ideal of beauty, where a slim figure is dominant, more frequently contributes to the occurrence of discrimination and stigmatization of overweight people. This phenomenon causes negative self-perception leading to the occurrence of such emotional problems as low self-esteem, lack of confidence, depression and anxiety disorders. Overweight children and adolescents are also frequently stigmatized and discriminated because of their body weight, which results in the development of a negative body image that may lead to low self-esteem and symptoms of depression. PMID:24575656

  1. Milk Fat Globule-Epidermal Growth Factor 8 (MFG-E8) Is a Novel Anti-inflammatory Factor in Rheumatoid Arthritis in Mice and Humans.

    PubMed

    Albus, Elise; Sinningen, Kathrin; Winzer, Maria; Thiele, Sylvia; Baschant, Ulrike; Hannemann, Anke; Fantana, Julia; Tausche, Anne-Kathrin; Wallaschofski, Henri; Nauck, Matthias; Völzke, Henry; Grossklaus, Sylvia; Chavakis, Triantafyllos; Udey, Mark C; Hofbauer, Lorenz C; Rauner, Martina

    2016-03-01

    Milk fat globule-epidermal growth factor 8 (MFG-E8) is an anti-inflammatory glycoprotein that mediates the clearance of apoptotic cells and is implicated in the pathogenesis of autoimmune and inflammatory diseases. Because MFG-E8 also controls bone metabolism, we investigated its role in rheumatoid arthritis (RA), focusing on inflammation and joint destruction. The regulation of MFG-E8 by inflammation was assessed in vitro using osteoblasts, in arthritic mice and in patients with RA. K/BxN serum transfer arthritis (STA) was applied to MFG-E8 knock-out mice to assess its role in the pathogenesis of arthritis. Stimulation of osteoblasts with lipopolysaccharide (LPS) and tumor necrosis factor (TNF)-α downregulated the expression of MFG-E8 by 30% to 35%. MFG-E8-deficient osteoblasts responded to LPS with a stronger production of pro-inflammatory cytokines. In vivo, MFG-E8 mRNA levels were 52% lower in the paws of collagen-induced arthritic (CIA) mice and 24% to 42% lower in the serum of arthritic mice using two different arthritis models (CIA and STA). Similarly, patients with RA (n = 93) had lower serum concentrations of MFG-E8 (-17%) compared with healthy controls (n = 140). In a subgroup of patients who had a moderate to high disease activity (n = 21), serum concentrations of MFG-E8 rose after complete or partial remission had been achieved (+67%). Finally, MFG-E8-deficient mice subjected to STA exhibited a stronger disease burden, an increased number of neutrophils in the joints, and a more extensive local and systemic bone loss. This was accompanied by an increased activation of osteoclasts and a suppression of osteoblast function in MFG-E8-deficient mice. Thus, MFG-E8 is a protective factor in the pathogenesis of RA and subsequent bone loss. Whether MFG-E8 qualifies as a novel biomarker or therapeutic target for the treatment of RA is worth addressing in further studies. © 2015 American Society for Bone and Mineral Research. PMID:26391522

  2. Factors influencing the undergraduate general education science curriculum

    NASA Astrophysics Data System (ADS)

    McWilliams, John Daniel

    The state of scientific literacy in the United States has been the focus of increasing concern in recent decades. A great deal of the blame for failing to produce citizens with a broad perspective in science has been placed on the undergraduate general education science curriculum. This was a national study designed to examine the factors that influence instructors' decision-making processes in designing the undergraduate general education science curriculum. The study also gathered information on the approaches used to present the curriculum. A mail-in questionnaire was used to collect data on the goals and factors that influence instructors' decisions related to the content of their courses, and on the associated characteristics of the instructors and programs. Questionnaires were returned by 85 instructors, representing a wide range of undergraduate programs in general education science. Data were analyzed by descriptive statistics, t-tests, and ANOVA, comparing respondents' mean ratings of factors and goals related to course content decisions. In making decisions, respondents assigned highest importance to the following factors: (a) instructor's philosophy of general education, (b) current and future needs of students, (c) demands of the discipline, and (d) the desire to incorporate an interdisciplinary perspective. Factors rated as least important were (a) recognition for tenure or promotion, (b) governmental requirements or regulations, and (c) guidance of a general education committee. As a goal for their course, respondents placed highest priority on developing students' science inquiry skills. Analysis by various groupings such as type of institution, instructor's education level, and years of teaching experience revealed few significant differences among respondents' ratings of factors and goals. Based on the findings of this study, recommendations for improving the general education science curriculum include (a) assisting instructors in developing and

  3. Factors influencing smokeless tobacco use in rural Ohio Appalachia.

    PubMed

    Nemeth, Julianna M; Liu, Sherry T; Klein, Elizabeth G; Ferketich, Amy K; Kwan, Mei-Po; Wewers, Mary Ellen

    2012-12-01

    The burden of smokeless tobacco (ST) use disproportionally impacts males in rural Ohio Appalachia. The purpose of this study was to describe the cultural factors contributing to this disparity and to articulate the way in which culture, through interpersonal factors (i.e. social norms and social networks) and community factors (i.e. marketing and availability), impacts ST initiation and use of ST among boys and men in Ohio Appalachia. Fifteen focus groups and 23 individual qualitative interviews were conducted with adult (n = 63) and adolescent (n = 53) residents in Ohio Appalachian counties to ascertain factors associated with ST use and the impact of ST marketing. Transcriptions were independently coded according to questions and themes. ST use appears to be a rite of passage in the development of masculine identity in Ohio Appalachian culture. Interpersonal factors had the greatest influence on initiation and continued use of ST. Ohio Appalachian boys either emulated current ST users or were actively encouraged to use ST through male family and peer networks. Users perceived their acceptance into the male social network as predicated on ST use. Community factors, including ST advertisement and access to ST, reinforced and normalized underlying cultural values. In addition to policy aimed at reducing tobacco marketing and access, interventions designed to reduce ST use in Ohio Appalachia should incorporate efforts to (1) shift the perception of cultural norms regarding ST use and (2) address male social networks as vehicles in ST initiation. PMID:22427033

  4. Factors Influencing Smokeless Tobacco Use in Rural Ohio Appalachia

    PubMed Central

    Nemeth, Julianna M.; Liu, Sherry T.; Klein, Elizabeth G.; Ferketich, Amy K.; Kwan, Mei-Po; Wewers, Mary Ellen

    2015-01-01

    Background The burden of smokeless tobacco (ST) use disproportionally impacts males in rural Ohio Appalachia. The purpose of this study was to describe the cultural factors contributing to this disparity and to articulate the way in which culture, through interpersonal factors (i.e. social norms and social networks) and community factors (i.e. marketing and availability), impacts ST initiation and use of ST among boys and men in Ohio Appalachia. Methods Fifteen focus groups and twenty-three individual qualitative interviews were conducted with adult (n=63) and adolescent (n=53) residents in Ohio Appalachian counties to ascertain factors associated with ST use and the impact of ST marketing. Transcriptions were independently coded according to questions and themes. Results ST use appears to be a rite of passage in the development of masculine identity in Ohio Appalachian culture. Interpersonal factors had the greatest influence on initiation and continued use of ST. Ohio Appalachian boys either emulated current ST users or were actively encouraged to use ST through male family and peer networks. Users perceived their acceptance into the male social network as predicated on ST use. Community factors, including ST advertisement and access to ST, reinforced and normalized underlying cultural values. Conclusions In addition to policy aimed at reducing tobacco marketing and access, interventions designed to reduce ST use in Ohio Appalachia should incorporate efforts to 1) shift the perception of cultural norms regarding ST use and 2) address male social networks as vehicles in ST initiation. PMID:22427033

  5. Factors influencing behavior in the forced swim test.

    PubMed

    Bogdanova, Olena V; Kanekar, Shami; D'Anci, Kristen E; Renshaw, Perry F

    2013-06-13

    The forced swim test (FST) is a behavioral test in rodents which was developed in 1978 by Porsolt and colleagues as a model for predicting the clinical efficacy of antidepressant drugs. A modified version of the FST added the classification of active behaviors into swimming and climbing, in order to facilitate the differentiation between serotonergic and noradrenergic classes of antidepressant drugs. The FST is now widely used in basic research and the pharmaceutical screening of potential antidepressant treatments. It is also one of the most commonly used tests to assess depressive-like behavior in animal models. Despite the simplicity and sensitivity of the FST procedure, important differences even in baseline immobility rates have been reported between different groups, which complicate the comparison of results across studies. In spite of several methodological papers and reviews published on the FST, the need still exists for clarification of factors which can influence the procedure. While most recent reviews have focused on antidepressant effects observed with the FST, this one considers the methodological aspects of the procedure, aiming to summarize issues beyond antidepressant action in the FST. The previously published literature is analyzed for factors which are known to influence animal behavior in the FST. These include biological factors, such as strain, age, body weight, gender and individual differences between animals; influence of preconditioning before the FST: handling, social isolation or enriched environment, food manipulations, various kinds of stress, endocrine manipulations and surgery; schedule and routes of treatment, dosage and type of the drugs as well as experimental design and laboratory environmental effects. Consideration of these factors in planning experiments may result in more consistent FST results. PMID:23685235

  6. Monitoring Athletes Through Self-Report: Factors Influencing Implementation

    PubMed Central

    Saw, Anna E.; Main, Luana C.; Gastin, Paul B.

    2015-01-01

    Monitoring athletic preparation facilitates the evaluation and adjustment of practices to optimize performance outcomes. Self-report measures such as questionnaires and diaries are suggested to be a simple and cost-effective approach to monitoring an athlete’s response to training, however their efficacy is dependent on how they are implemented and used. This study sought to identify the perceived factors influencing the implementation of athlete self-report measures (ASRM) in elite sport settings. Semi-structured interviews were conducted with athletes, coaches and sports science and medicine staff at a national sporting institute (n = 30). Interviewees represented 20 different sports programs and had varying experience with ASRM. Purported factors influencing the implementation of ASRM related to the measure itself (e.g., accessibility, timing of completion), and the social environment (e.g., buy-in, reinforcement). Social environmental factors included individual, inter-personal and organizational levels which is consistent with a social ecological framework. An adaptation of this framework was combined with the factors associated with the measure to illustrate the inter-relations and influence upon compliance, data accuracy and athletic outcomes. To improve implementation of ASRM and ultimately athletic outcomes, a multi-factorial and multi-level approach is needed. Key points Effective implementation of a self-report measure for monitoring athletes requires a multi-factorial and multi-level approach which addresses the particular measure used and the surrounding social environment. A well-designed self-report measure should obtain quality data with minimal burden on athletes and staff. A supportive social environment involves buy-in and coordination of all parties, at both an individual and organization level. PMID:25729301

  7. Factors associated with variation in bulk tank milk Mycoplasma bovis antibody-ELISA results in dairy herds.

    PubMed

    Petersen, Mette B; Krogh, Kaspar; Nielsen, Liza R

    2016-05-01

    The relevance and limitations for using measurements of antibodies against Mycoplasma bovis in bulk tank milk (BTM) as a potentially cost-effective diagnostic tool for herd classification has not been evaluated before. Assuming that an increasing or high seroprevalence is a result of on-going or recent spread of M. bovis in a dairy herd, we tested the hypothesis that increasing prevalence of antibody-positive cows and young stock are associated with increasing BTM antibody ELISA values against M. bovis in Danish dairy herds with different courses of M. bovis infection. Furthermore, we tested whether herd size was associated with variations in the BTM responses. Thirty-nine Danish dairy herds selected to represent 4 different herd-level infection groups [8 control herds, 14 acute outbreak herds, 7 herds with previous outbreaks, and 10 herds with elevated BTM ELISA-values directed against M. bovis (>64% optical density measurement)] were visited 4 to 5 times, approximately 3mo apart. At each visit, 65 young stock were blood sampled. At the milk recording date closest to the herd visit date, 50 milk recording samples from individual lactating cows were randomly selected. In addition, a BTM sample was collected as a representative sample directly from the bulk tank by the dairies' milk truck drivers as part of the mandatory milk quality-control scheme. Blood and milk samples were tested for antibodies against M. bovis with a commercially available ELISA test (Bio-X BIO K 302, Bio-X Diagnostics, Rochefort, Belgium). A linear mixed effects model was used to analyze the effects of the prevalence of antibody-positive lactating cows and young stock and herd size on the BTM M. bovis ELISA results. Herd was included as a random effect to account for clustering of BTM samples originating from the same herd. Increasing prevalence of antibody-positive lactating cows was the only variable associated with increasing M. bovis BTM ELISA optical density measurement. In contrast, the

  8. Factors influencing physicians' knowledge sharing on web medical forums.

    PubMed

    Lin, Tung Cheng; Lai, Ming Cheng; Yang, Shu Wen

    2016-09-01

    Web medical forums are relatively unique as knowledge-sharing platforms because physicians participate exclusively as knowledge contributors and not as knowledge recipients. Using the perspective of social exchange theory and considering both extrinsic and intrinsic motivations, this study aims to elicit the factors that significantly influence the willingness of physicians to share professional knowledge on web medical forums and develops a research model to explore the motivations that underlie physicians' knowledge-sharing attitudes. This model hypothesizes that constructs, including shared vision, reputation, altruism, and self-efficacy, positively influence these attitudes and, by extension, positively impact knowledge-sharing intention. A conventional sampling method and the direct recruitment of physicians at their outpatient clinic gathered valid data from a total of 164 physicians for analysis in the model. The empirical results support the validity of the proposed model and identified shared vision as the most significant factor of influence on knowledge-sharing attitudes, followed in descending order by knowledge-sharing self-efficacy, reputation, and altruism. PMID:25888432

  9. Factors influencing the microbial safety of fresh produce: a review.

    PubMed

    Olaimat, Amin N; Holley, Richard A

    2012-10-01

    Increased consumption, larger scale production and more efficient distribution of fresh produce over the past two decades have contributed to an increase in the number of illness outbreaks caused by this commodity. Pathogen contamination of fresh produce may originate before or after harvest, but once contaminated produce is difficult to sanitize. The prospect that some pathogens invade the vascular system of plants and establish "sub-clinical" infection needs to be better understood to enable estimation of its influence upon risk of human illness. Conventional surface sanitation methods can reduce the microbial load, but cannot eliminate pathogens if present. Chlorine dioxide, electrolyzed water, UV light, cold atmospheric plasma, hydrogen peroxide, organic acids and acidified sodium chlorite show promise, but irradiation at 1 kGy in high oxygen atmospheres may prove to be the most effective means to assure elimination of both surface and internal contamination of produce by pathogens. Pathogens of greatest current concern are Salmonella (tomatoes, seed sprouts and spices) and Escherichia coli O157:H7 on leafy greens (spinach and lettuce). This review considers new information on illness outbreaks caused by produce, identifies factors which influence their frequency and size and examines intervention effectiveness. Research needed to increase our understanding of the factors influencing microbial safety of fresh produce is addressed. PMID:22850369

  10. [Factors influencing psychotherapeutic treatment outcome of various syndromes].

    PubMed

    Hartmann, Sebastian; Zepf, Siegfried

    2004-12-01

    The authors investigated specific and unspecific factors influencing the psychotherapeutic treatment of various syndromes using a questionnaire which systematically replicated the Consumer Reports Study performed in the USA in 1994. The authors were particularly concerned with the degree to which certain psychotherapeutic methods - psychoanalysis, depth psychology-based psychotherapy and behavioral therapy - produced differing results following treatment of syndromes. Using cluster-analysis, two groups of syndromes could be distinguished: Patients with depressive symptoms, stress-related disorders and/or relationship problems (depression-group) and patients with anxiety disorders and/or eating-related disorders (anxiety-group). With the help of cart-analysis (Classification and Regression Trees) it was possible to identify factors influencing the improvement of symptoms. The method of treatment had not a specific effect on the improvement of symptoms. In both groups the most important predictor was the length of treatment. Furthermore in the depression group the sex of the patients and a possible restriction of the treatment by the health insurance companies influenced the treatment results and in the anxiety group the frequency of treatment and the age of the patients. PMID:15551189

  11. Association between CSN3 and BCO2 gene polymorphisms and milk performance traits in the Czech Fleckvieh cattle breed.

    PubMed

    Bartonova, P; Vrtkova, I; Kaplanova, K; Urban, T

    2012-01-01

    Daily milk, fat and protein yield and amount of somatic cells in cow milk are very important factors that influence milk performance traits. An association between polymorphisms in the kappa casein (CSN3) gene and milk production, composition and technical properties has been previously reported; however, this type of information is not available for the bovine β-carotene oxygenase 2 (BCO2) gene--the BCO2 gene has relationship with milk color and meat fat color, which is dependent on content of β-carotene. We analyzed these two genes and their relationship with milk performance traits (daily milk, fat and protein yield, somatic cell count, SCC) in one cattle population, Czech Fleckvieh (N = 152). All animals were milked twice a day and kept in the same environmental conditions. The Fleckvieh is a typical Czech cattle breed farming for milk and meat production. It is the most common breed in the Czech Republic. DNA was isolated from milk or from hairs. Genes were analyzed using PCR-RFLP, frequencies of alleles and genotypes were calculated and association analysis was performed using a GLM Procedure in SAS. Statistical analysis established that the CSN3 gene has no statistically significant influence on daily milk, fat and protein yield and SCC. Compared to other references this result can be explained by, e.g., small group of animals and different cattle breed. The BCO2 gene (genotypes AA and AG) shows a statistically significant relationship (P = 0.05) with daily milk, protein yield and SCC. PMID:22614274

  12. High Enrollment Course Success Factors in Virtual School: Factors Influencing Student Academic Achievement

    ERIC Educational Resources Information Center

    Liu, Feng; Cavanaugh, Cathy

    2011-01-01

    This paper describes a study of success factors in high enrollment courses in a K-12 virtual school learning environment. The influence of variables: time student spent in the learning management system (LMS), number of times logged into the LMS, teacher comment, participation in free or reduced lunch programs, student status in the virtual school…

  13. Influence of replacing corn silage with barley silage in the diets of buffalo cows on milk yield and quality.

    PubMed

    Tudisco, R; Calabrò, S; Grossi, M; Piccolo, G; Guglielmelli, A; Cutrignelli, M I; Caiazzo, C; Infascelli, F

    2010-06-01

    A 150-day trial was carried out on 40 Italian Mediterranean buffalo cows that, immediately after calving, were equally divided into two homogeneous groups (M and O) based on the number of calving events and previous milk yield. The animals were fed (16 kg dry matter (DM)/head) two isoenergy/isoprotein diets (NEl: 6.39 MJ/kg DM; 15.4 CP% DM), composed of corn (diet M) or barley silage (diet O) concentrate, alfalfa hay, and a vitamin-mineral supplement. The fermentation characteristics of both silage diets were evaluated by an in vitro gas production technique, and their nutritional values were calculated as follows: NEl (MJ/kg DM) = 0.54 + 0.0959 GP + 0.0038 CP + 0.0001733 CP(2), where GP is the gas production after 24 h of incubation (ml/200 mg DM) and CP is the protein content of silage (g/kg DM). The nutritional values of the silages were slightly different (4.16 vs. 4.14 MJ/kg DM for M and O, respectively) likely due to the high content of hemicellulose in the O diet (22.0 vs. 16.9%). Average milk yield did not differ between the groups; instead, milk fat (8.39 vs. 9.06%; P < 0.01) and protein (4.41 vs. 4.60%; P < 0.01) levels were significantly higher in the O group. The results elicit great interest in southern Italy where corn cultivation is adversely affected by the high cost of irrigation. PMID:20464483

  14. Influence of a Spirulina platensis biomass on the microflora of fermented ABT milks during storage (R1).

    PubMed

    Varga, L; Szigeti, J; Kovács, R; Földes, T; Buti, S

    2002-05-01

    The objective of this research was to investigate the effect of a cyanobacterial (Spirulina platensis) biomass on the microflora of a probiotic fermented dairy product during storage at two temperatures. Spirulina-enriched and control (plain) fermented acidophilus-bifidus-thermophilus (ABT) milks were produced using a fast fermentation starter culture (ABT-4) as the source of Lactobacillus acidophilus (A), bifidobacteria (B), and Streptococcus thermophilus (T). Incubation took 6 h at 40 degrees C. As for the cyanobacterial product, the S. platensis biomass was added to the process milk during stirring at pH 4.5 to 4.6. Thereafter, the ABT-type fermented milks were cooled to 25 degrees C in ice water, filled into sterile, tightly capped centrifuge tubes, further cooled at 4 degrees C for 24 h, and then stored either at 15 degrees C for 18 d or at 4 degrees C for 42 d. Microbiological analyses and acidity measurements were performed at regular intervals. Our results showed that the counts of the starter organisms were satisfactory during the entire storage period at both temperatures applied in this research. The S. platensis biomass had a beneficial effect on the survival of ABT starter bacteria regardless of storage temperature. Postacidification was observed at 15 degrees C, whereas pH remained stable during refrigerated storage at 4 degrees C. The abundance of bioactive substances in S. platensis is of great importance from a nutritional point of view because thus the cyanobacterial biomass provides a new opportunity for the manufacture of functional dairy foods. PMID:12086036

  15. Milk Allergy

    MedlinePlus

    ... the word “Milk” on the label. Read all product labels carefully before purchasing and consuming any item. Ingredients ... following the circled K or U on a product label indicates the presence of milk protein or a ...

  16. PMR Characterization of the Water Structure in Tibetan Milk Mushroom Zooglea: Influence of Medium Hydration and Hydrophobicity

    NASA Astrophysics Data System (ADS)

    Krupskaya, T. V.; Prylutskyy, Yu. I.; Evstigneev, M. P.; Tsapko, M. D.; Turov, V. V.

    2015-07-01

    The state of water in Tibetan milk mushroom zooglea with different degrees of hydration (h) was investigated using low-temperature PMR spectroscopy in air and in contact with the hydrophobic media polydimethylsiloxane PDMS-1000 and CHCl3 with added trifl uoroacetic acid (TFA). The maximum hydration of the zooglea amounted to h = 32 g/g (of dry matter). Water existed as polyassociates (clusters or domains) of strongly and weakly associated water. Bound water decomposed into clusters in the presence of TFA. The NMR spectra showed six types of bound water at h = 0.3 g/g.

  17. Got milk?

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    While celebrities wear white “milk moustaches” in a popular U.S. advertising campaign to promote the drinking of milk, they should also be concerned about the decreased amount of calcium available to many trees.Calcium levels in forest soils have decreased at locations in 10 states in the eastern United States, according to a new report by the U.S. Geological Survey (USGS) released in time for National Arbor Day on April 30.

  18. Expecting success: Factors influencing ninth graders' science self-efficacy

    NASA Astrophysics Data System (ADS)

    Donahue, Elizabeth

    What factors influence ninth grade students' expectations for success in science? Using social cognitive theory and bioecological systems theory as theoretical frameworks, this dissertation employs data from the High School Longitudinal Study of 2009 (HSLS:09) to examine the relative impact of teacher practices and their perceived attitudes on students' science self-efficacy. Further, as they relate to this broader issue, the relative impact of student subjective task value and teacher characteristics is also investigated. It has been well documented that U.S. students are not achieving at satisfactory levels in science. Education policy has focused on improving science teacher quality as one way to address this problem. Teacher effectiveness has been primarily measured by student achievement on standardized tests. However, not enough attention has been given to the social cognitive factors that can lead to increased achievement and persistence in science as well as how teachers may influence these factors. This study interrogates the relationship between student and teacher variables and the social cognitive construct of self-efficacy, which has proven to have a significant impact on student achievement and persistence in science. Findings add to the current literature surrounding ways that educators may increase student performance in science by employing policies and practices that benefit the development of student science self-efficacy.

  19. Factors influencing candidates' choice of a pediatric dental residency program.

    PubMed

    da Fonseca, Marcio A; Pollock, Matthew; Majewski, Robert; Tootla, Ruwaida; Murdoch-Kinch, Carol Anne

    2007-09-01

    The goal of this study was to identify the factors and program characteristics that influenced the program ranking decisions of applicants to pediatric dentistry residency programs. A questionnaire was sent to the first-year resident class in 2005 with a response rate of 69.2 percent (n=260). Approximately 55 percent were female (104/180) and 61 percent were non-His-panic white (110/180). The respondents reported that they applied to an average of nine programs, of which five were ranked. Most applicants were interested in a program that had a hospital component with a duration of two years. A program's ability to prepare the resident for an academic career was a minimal influence for 48.6 percent (87/179), and 57.5 percent (103/179) were not interested in a master's or Ph.D. degree. Factors associated with program ranking included modern clinical facilities, high ratio of dental assistants and faculty to residents, availability of assistants for sedation and general anesthesia cases, availability of a salary or stipend, and amount of clinical experience. Important non-clinical factors included hospitality during the interview, geographic location, and perceived reputation of the program. Opportunity to speak with the current residents in private, observing the interaction between residents and faculty, and touring the facilities were also highly considered. These findings may help program directors tailor their interviews and programs to suit the needs of applicants. PMID:17761626

  20. Factors Influencing the Management of Unruptured Intracranial Aneurysms

    PubMed Central

    Podraza, Katherine M; Luthra, Nijee; Origitano, Thomas C; Schneck, Michael J

    2016-01-01

    Background Deciding how to manage an unruptured intracranial aneurysm can be difficult for patients and physicians due to controversies about management. The decision as to when and how to intervene may be variable depending on physicians’ interpretation of available data regarding natural history and morbidity and mortality of interventions. Another significant factor in the decision process is the patients’ conception of the risks of rupture and interventions and the psychological burden of harboring an unruptured intracranial aneurysm. Objective  To describe which factors are being considered when patients and their physicians decide how to manage unruptured intracranial aneurysms.  Materials & methods  In a retrospective chart review study, we identified patients seen for evaluation of an unruptured intracranial aneurysm. Data was collected regarding patient and aneurysm characteristics. The physician note pertaining to the management decision was reviewed for documented reasons for intervention. Results  Of 88 patients included, 36 (41%) decided to undergo open or endovascular surgery for at least one unruptured intracranial aneurysm. Multiple aneurysms were present in 14 (16%) patients. Younger patients and current smokers were more likely to undergo surgery, but gender and race did not affect management. Aneurysm size and location strongly influenced management. The most common documented reasons underlying the decision of whether to intervene were the risk of rupture, aneurysm size, and risks of the procedure. For 23 aneurysms (21%), there were no factors documented for the management decision.  Conclusion  The risk of rupture of unruptured intracranial aneurysms may be underestimated by currently available natural history data. Major factors weighed by physicians in management decisions include aneurysm size and location, the patient's age, and medical comorbidities along with the risk of procedural complications. Additional data is needed to

  1. Factors Influencing the Management of Unruptured Intracranial Aneurysms.

    PubMed

    Gillani, Rebecca L; Podraza, Katherine M; Luthra, Nijee; Origitano, Thomas C; Schneck, Michael J

    2016-01-01

    Background Deciding how to manage an unruptured intracranial aneurysm can be difficult for patients and physicians due to controversies about management. The decision as to when and how to intervene may be variable depending on physicians' interpretation of available data regarding natural history and morbidity and mortality of interventions. Another significant factor in the decision process is the patients' conception of the risks of rupture and interventions and the psychological burden of harboring an unruptured intracranial aneurysm. Objective  To describe which factors are being considered when patients and their physicians decide how to manage unruptured intracranial aneurysms.  Materials & methods  In a retrospective chart review study, we identified patients seen for evaluation of an unruptured intracranial aneurysm. Data was collected regarding patient and aneurysm characteristics. The physician note pertaining to the management decision was reviewed for documented reasons for intervention. Results  Of 88 patients included, 36 (41%) decided to undergo open or endovascular surgery for at least one unruptured intracranial aneurysm. Multiple aneurysms were present in 14 (16%) patients. Younger patients and current smokers were more likely to undergo surgery, but gender and race did not affect management. Aneurysm size and location strongly influenced management. The most common documented reasons underlying the decision of whether to intervene were the risk of rupture, aneurysm size, and risks of the procedure. For 23 aneurysms (21%), there were no factors documented for the management decision.  Conclusion  The risk of rupture of unruptured intracranial aneurysms may be underestimated by currently available natural history data. Major factors weighed by physicians in management decisions include aneurysm size and location, the patient's age, and medical comorbidities along with the risk of procedural complications. Additional data is needed to define

  2. Comparative expression profiling of insulin-like growth factor binding protein-5 in milk of Bos indicus and Bubalus bubalis during lactation.

    PubMed

    Mohapatra, S K; Singh, S; Kumar, S; Dang, A K; Datta, T K; Das, S K; Mohanty, T K; Kaushik, J K; Mohanty, A K

    2015-04-01

    Insulin-like growth factor binding protein-5 (IGFBP-5) is a key molecule in mammary gland development, which facilitates the removal of mammary epithelial cells (MECs) by apoptosis that takes place during remodeling of the mammary gland during involution. IGFBP-5 binds with IGFs for their bioavailability. IGFBP-5 has been reported to perform pleiotropic roles such as cellular apoptosis, proliferation and differentiation. To understand the role of IGFBP-5 during lactation and clinical mastitis, expression profiling of IGFBP-5 at the protein level was performed in both indigenous cows (Bos indicus) and buffaloes (Bubalus bubalis) belonging to two different breeds - Sahiwal cows and Murrah buffaloes. Reverse-transcriptase PCR (RT-PCR) of IGFBP-5 mRNA confirmed its expression in milk somatic cells and MECs of Sahiwal cows. ELISA was performed for quantitative measurement of IGFBP-5 concentrations in milk during different days (0, 50, 100, 150, 200, 250 and 300) of lactation, during the involution period and in animals exhibiting short lactation and clinical mastitis. The highest concentration of IGFBP-5 in milk was observed during the involution period followed by colostrum, late and early lactation, respectively, in both cattle and buffaloes. No significant difference in the concentration of IGFBP-5 was observed during the first 150 days of lactation between cows and buffaloes. However, higher concentration of IGFBP-5 was observed in cows during late lactation (200 to 300 days) in comparison with buffaloes. To validate the ELISA data, quantitative real-time PCR was performed in MECs of Sahiwal cows. The relative mRNA abundance of IGFBP-5 was found to be significantly (P<0.05) higher on day 15 than between 50 and 150 days of lactation in case of Sahiwal cows. Highest mRNA expression of IGFBP-5 was observed around 300 days of lactation followed by 200 and 250 days (P<0.05), respectively. Murrah buffaloes showed low levels of IGFBP-5 protein in milk as compared with

  3. Mechanisms and Factors that Influence High Frequency Retroviral Recombination

    PubMed Central

    Delviks-Frankenberry, Krista; Galli, Andrea; Nikolaitchik, Olga; Mens, Helene; Pathak, Vinay K.; Hu, Wei-Shau

    2011-01-01

    With constantly changing environmental selection pressures, retroviruses rely upon recombination to reassort polymorphisms in their genomes and increase genetic diversity, which improves the chances for the survival of their population. Recombination occurs during DNA synthesis, whereby reverse transcriptase undergoes template switching events between the two copackaged RNAs, resulting in a viral recombinant with portions of the genetic information from each parental RNA. This review summarizes our current understanding of the factors and mechanisms influencing retroviral recombination, fidelity of the recombination process, and evaluates the subsequent viral diversity and fitness of the progeny recombinant. Specifically, the high mutation rates and high recombination frequencies of HIV-1 will be analyzed for their roles in influencing HIV-1 global diversity, as well as HIV-1 diagnosis, drug treatment, and vaccine development. PMID:21994801

  4. Factors influencing reductions in smoking among Australian adolescents.

    PubMed

    Dessaix, Anita; Maag, Audrey; McKenzie, Jeanie; Currow, David C

    2016-01-01

    A continued increase in the proportion of adolescents who never smoke, as well as an understanding of factors that influence reductions in smoking among this susceptible population, is crucial. The World Health Organization Framework Convention on Tobacco Control provides an appropriate structure to briefly examine Australian and New South Wales policies and programs that are influencing reductions in smoking among adolescents in Australia. This paper provides an overview of price and recent tax measures to reduce the demand for tobacco, the evolution of smoke-free environment policies, changes to tobacco labelling and packaging, public education campaigns, and restrictions to curb tobacco advertising. It also discusses supplyreduction measures that limit adolescents' access to tobacco products. Consideration is given to emerging priorities to achieve continued declines in smoking by Australian adolescents. PMID:26863168

  5. Nontechnical skills in pediatric surgery: Factors influencing operative performance.

    PubMed

    Youngson, George G

    2016-02-01

    Technical competence is an essential aspect of intraoperative performance but is in itself insufficient to ensure an optimal surgical outcome. A list of other skills complement technical ability and these relate, among others, to surgical judgment and intraoperative decision-making processes as well as the role of the operating surgeon as leader of the surgical team. This article outlines the composite set of nontechnical skills (NTS) and the factors which influence surgical performance by virtue of this skill set. A framework has been developed to allow identification, teaching, and assessment of NTS known as Nontechnical Skills for Surgeons (NOTSS), and the relevance and influence of NOTSS during the intraoperative performance of pediatric surgery is presented. PMID:26644073

  6. Acne vulgaris: nutritional factors may be influencing psychological sequelae.

    PubMed

    Katzman, Martin; Logan, Alan C

    2007-01-01

    Acne vulgaris is a distressing skin condition which can carry with it significant psychological disability. Patients with acne are more likely to experience anger and are at increased risk of depression, anxiety, suicidal ideation. Certain nutrients which have been implicated as influencing the pathophysiology of acne have also been identified as important mediators of human cognition, behavior and emotions. Zinc, folic acid, selenium, chromium and omega-3 fatty acids are all examples of nutrients which have been shown to influence depression, anger and/or anxiety. These same nutrients, along with systemic oxidative stress and an altered intestinal microflora have been implicated in acne vulgaris. It is our contention that certain nutritional factors, a weakened antioxidant defense system and altered intestinal microflora may interplay to increase the risk of psychological sequelae in acne vulgaris. PMID:17448607

  7. Nutritional Factors Influencing Intestinal Health of the Neonate12

    PubMed Central

    Jacobi, Sheila K.; Odle, Jack

    2012-01-01

    Dietary nutrients are essential for gastrointestinal (GI) growth and function, and nutritional support of GI growth and development is a significant component of infant care. For healthy full-term neonates, nutritional provisions of the mother’s milk and/or formula will support normal maturation of structure and function of the GI tract in most infants. The composition of breast milk affects GI barrier function and development of a competent mucosal immune system. The functional nutrients and other bioactive components of milk support a microenvironment for gut protection and maturation. However, premature infants struggle with feeding tolerance impairing normal GI function, leading to intestinal dysfunction and even death. The high prevalence worldwide of enteric diseases and dysfunction in neonates has led to much interest in understanding the role of nutrients and food components in the establishment and maintenance of a functioning GI tract. Neonates who do not receive enteral feeding as either mother’s milk or formula are supported by total parental nutrition (TPN). The lack of enteral nutrition can compound intestinal dysfunction, leading to high morbidity and mortality in intestinally compromised infants. Reciprocally, enteral stimulation of an immature GI tract can also compound intestinal dysfunction. Therefore, further understanding of nutrient interactions with the mucosa is necessary to define nutritional requirements of the developing GI tract to minimize intestinal complications and infant morbidity. Piglet models of intestinal development and function are similar to humans, and this review summarizes recent findings regarding nutrient requirements for growth and maintenance of intestinal health. In particular, this article reviews the role of specific amino acids (arginine, glutamine, glutamate, and threonine), fatty acids (long chain polyunsaturated, medium chain, and short chain), various prebiotic carbohydrates (short-chain fructo

  8. Nutritional factors influencing intestinal health of the neonate.

    PubMed

    Jacobi, Sheila K; Odle, Jack

    2012-01-01

    Dietary nutrients are essential for gastrointestinal (GI) growth and function, and nutritional support of GI growth and development is a significant component of infant care. For healthy full-term neonates, nutritional provisions of the mother's milk and/or formula will support normal maturation of structure and function of the GI tract in most infants. The composition of breast milk affects GI barrier function and development of a competent mucosal immune system. The functional nutrients and other bioactive components of milk support a microenvironment for gut protection and maturation. However, premature infants struggle with feeding tolerance impairing normal GI function, leading to intestinal dysfunction and even death. The high prevalence worldwide of enteric diseases and dysfunction in neonates has led to much interest in understanding the role of nutrients and food components in the establishment and maintenance of a functioning GI tract. Neonates who do not receive enteral feeding as either mother's milk or formula are supported by total parental nutrition (TPN). The lack of enteral nutrition can compound intestinal dysfunction, leading to high morbidity and mortality in intestinally compromised infants. Reciprocally, enteral stimulation of an immature GI tract can also compound intestinal dysfunction. Therefore, further understanding of nutrient interactions with the mucosa is necessary to define nutritional requirements of the developing GI tract to minimize intestinal complications and infant morbidity. Piglet models of intestinal development and function are similar to humans, and this review summarizes recent findings regarding nutrient requirements for growth and maintenance of intestinal health. In particular, this article reviews the role of specific amino acids (arginine, glutamine, glutamate, and threonine), fatty acids (long chain polyunsaturated, medium chain, and short chain), various prebiotic carbohydrates (short-chain fructo

  9. Factors influencing choice of dental treatment by private general practitioners.

    PubMed

    Brennan, David S; Spencer, A John

    2002-01-01

    Service rate variations have focused attention on treatment decisions. The aims of this study were to examine factors considered in choosing treatments, to classify dentists in terms of clinical decision making, and to investigate the association of decision making with services provided. From a random sample of dentists (response rate 60.3%) treatment constraints (15.0%), periodontal status (12.1%), tooth status (11.3%), mouth status (10.1%), and patient factors (9.8%) were considered important factors across six alternative treatment pair choice scenarios. Cluster analysis of the treatment choice scenarios produced one cluster that reflected patient preferences, another that reflected treatment constraints such as cost, and a third that reflected oral health factors. Compared with the oral health cluster, dentists in the constraints cluster had higher rates (p < .05) of extractions (rate ratio [RR] = 1.49), bridge work (RR = 1.77), and dentures (RR = 1.32), whereas dentists in the patient cluster had higher restoration rates for two-surface ionomers (RR = 2.45) and resins on three or more surfaces (RR = 1.50) and other preventive services (RR = 1.78) such as oral hygiene instruction. Although a range of factors influenced treatment choice, a limited set accounted for the majority of responses, with cost a major determinant, ahead of oral health status and patient preference. Decision-making style was associated with service provision. PMID:12174535

  10. Storage of refrigerated raw goat milk affecting the quality of whole milk powder.

    PubMed

    Fonseca, C R; Bordin, K; Fernandes, A M; Rodrigues, C E C; Corassin, C H; Cruz, A G; Oliveira, C A F

    2013-07-01

    The aim of this study was to evaluate the influence of the growth of lipolytic bacteria in raw goat milk stored under refrigeration for different periods on quality parameters of goat milk powder during its shelf life. Fresh goat milk (100L) was collected after milking, divided into 3 identical fractions, and stored at 4°C for 1, 3, and 5d. On d 1, 3, and 5, one sample (1L) was collected and used for microbiological and chemical analysis, and the remaining fraction (almost 30L) was spray dried and stored at 25°C. Milk powder was submitted to microbiological, chemical, and sensory analysis immediately after production, and on d 60, 120, and 180. Lipolytic psychrotrophic counts and total free fatty acid content did not increase in raw milk during storage. However, peroxide value, caprylic and capric acid concentrations, and total free fatty acid content of milk powder increased during 180d of storage, with higher levels found in milk powder manufactured with raw milk stored for 5d. Capric odor and rancid flavors increased in milk powder during storage, regardless the of storage of raw milk for 1, 3, or 5d. Heat treatments used during powder processing destroyed lipolytic psychrotrophic bacteria, but did not prevent lipolysis in milk powder. Results of this trial indicate that the storage of raw goat milk at 4°C should not exceed 3d to preserve the quality of goat milk powder during its shelf life of 180d. PMID:23664351

  11. Factors influencing stakeholders attitudes toward genetically modified aedes mosquito.

    PubMed

    Amin, Latifah; Hashim, Hasrizul

    2015-06-01

    Dengue fever is a debilitating and infectious disease that could be life-threatening. It is caused by the dengue virus which affects millions of people in the tropical area. Currently, there is no cure for the disease as there is no vaccine available. Thus, prevention of the vector population using conventional methods is by far the main strategy but has been found ineffective. A genetically modified (GM) mosquito is among the favoured alternatives to curb dengue fever in Malaysia. Past studies have shown that development and diffusion of gene technology products depends heavily upon public acceptance. The purpose of this study is to identify the relevant factors influencing stakeholders' attitudes toward the GM Aedes mosquito and to analyse the relationships between all the factors using the structural equation model. A survey was carried out on 509 respondents from various stakeholder groups in the Klang Valley region of Malaysia. Results of the survey have confirmed that public perception towards complex issues such as gene technology should be seen as a multi-faceted process. The perceived benefit-perceived risk balance is very important in determining the most predominant predictor of attitudes toward a GM mosquito. In this study the stakeholders perceived the benefit of the GM mosquito as outweighing its risk, translating perceived benefit as the most important direct predictor of attitudes toward the GM mosquito. Trust in key players has a direct influence on attitudes toward the GM mosquito while moral concern exhibited an indirect influence through perceived benefits. Other factors such as attitudes toward technology and nature were also indirect predictors of attitudes toward the GM mosquito while religiosity and engagement did not exhibited any significant roles. The research findings serve as a useful database to understand public acceptance and the social construct of public attitudes towards the GM mosquito to combat dengue. PMID:24906652

  12. Factors influencing dairy calf and replacement heifer mortality in France.

    PubMed

    Raboisson, D; Maigne, E; Sans, P; Allaire, G; Cahuzac, E

    2014-01-01

    Herd-level risk factors for dairy calf and heifer mortality in France were identified by calculating herd-level variables (including mortality risk or rate) using the National Bovine Identification Database (2005 and 2006). Eleven dairy production areas representing different livestock systems were also included. Statistical analyses were based on a probit model (mortality risk or rate=0 or >0) and a linear model (mortality risk or rate >0) corrected by the sample bias Heckman method. The same associations were reported for 2005 and 2006. The mortality risks or rates for calves and heifers were positively associated with the proportion of purchased cows or being a Milk Control Program member and negatively associated with adhering to the Good Breeding Practices charter and having an autumn calving peak. The associations between mortality and the breeds or the production areas were positive or negative, depending on the classes of animal. Mortality and having a beef herd in addition to the dairy herd were negatively associated for noncrossed birth to 2-d-old calves, noncrossed 3-d- to 1-mo-old calves, and 3-d- to 1-mo-old heifers. Having a beef herd probably provides specific know-how related to newborn and young calf management that makes it easier to attain low mortality in pure-breed dairy calves. The proportion of males born was positively associated with mortality for the birth to 2-d-old calves (all classes) and for the 3-d- to 1-mo-old beef-crossed calves, but negatively for all classes of heifers. This indicates that heifer management was improved when the availability of newborn heifers decreased, resulting in low mortality. This lower mortality is apparent for all classes of heifers present on the farm during the year when the proportion of males was low, and demonstrates an anticipatory effect. In conclusion, this study shows that the presence of a beef herd in addition to the dairy herd within a farm is associated with decreased dairy calf mortality. It

  13. Factors influencing trace element composition in human teeth

    SciTech Connect

    Tandon, L.; Iyengar, G.V.

    1997-12-01

    The authors recently compiled and reviewed the literature published in or after 1978 for 45 major, minor, and trace elements in human teeth as a part of an International Atomic Energy Agency (IAEA) study. The purpose of this paper is to discuss the various factors that influence the concentration levels of certain trace elements in human teeth. The sampling practices and analytical techniques that are applicable for trace element analysis are also discussed. It is also our intention to identify reference range of values, where data permit such conclusions. The scrutiny was designed to identify only the healthy permanent teeth, and values from teeth with fillings, caries, or periodontal diseases were eliminated.

  14. Factors influencing evidence-based practice for community nurses.

    PubMed

    Baird, Lisa M Garland; Miller, Tess

    2015-05-01

    Factors influencing the development of evidence-based nursing practice (EBNP) were examined in Prince Edward Island, Canada. An adapted electronic questionnaire was distributed to practicing registered nurses and nurse practitioners (n=68). An analysis of variance revealed a significant difference between nurses' clinical practice setting and the EBNP scale. Significant differences were also found between age and education level when compared with the EBNP subscales where novice nurses were less likely to rely on experience and intuition, and expert nurses with a higher level of education reported being more skilful at synthesising and applying information from research findings into their nursing practice. PMID:25993372

  15. The influence of environmental factors on bone tissue engineering.

    PubMed

    Szpalski, Caroline; Sagebin, Fabio; Barbaro, Marissa; Warren, Stephen M

    2013-05-01

    Bone repair and regeneration are dynamic processes that involve a complex interplay between the substrate, local and systemic cells, and the milieu. Although each constituent plays an integral role in faithfully recreating the skeleton, investigators have long focused their efforts on scaffold materials and design, cytokine and hormone administration, and cell-based therapies. Only recently have the intangible aspects of the milieu received their due attention. In this review, we highlight the important influence of environmental factors on bone tissue engineering. PMID:23165885

  16. Factors Influencing Dating Experiences Among African American Emerging Adults

    PubMed Central

    Hall, Naomi M.; Lee, Anna K.; Witherspoon, Daphne D.

    2014-01-01

    This study examined sociocultural factors that impact dating and sexual experiences of heterosexual African American undergraduate college students attending a historically Black institution in the Southeastern United States. Specifically, mate availability and relationship involvement were analyzed to document students’ experiences, and how these influences may be associated with sexual decision making and behavior. Data from nine focus groups (N = 57) were aggregated and four subthemes were identified: competition among women, acceptability of mates, high prevalence of casual relationships, and lowered expectations for commitment. Power dynamics emerged as a contributing factor to the types of relationship involvement, sexual decision-making, and behavior among participants. The importance of prevention programs focusing on situational and cultural variables is highlighted. Additionally, implications for professionals working with emerging adults to consider the impact of the gender ratio imbalance, and perceived power distributions on perceptions of dating relationships, and sexual decision making and behavior are addressed. PMID:25530924

  17. Influence of Lifestyle Factors on Mammographic Density in Postmenopausal Women

    PubMed Central

    Brand, Judith S.; Czene, Kamila; Eriksson, Louise; Trinh, Thang; Bhoo-Pathy, Nirmala; Hall, Per; Celebioglu, Fuat

    2013-01-01

    Background Mammographic density is a strong risk factor for breast cancer. Apart from hormone replacement therapy (HRT), little is known about lifestyle factors that influence breast density. Methods We examined the effect of smoking, alcohol and physical activity on mammographic density in a population-based sample of postmenopausal women without breast cancer. Lifestyle factors were assessed by a questionnaire and percentage and area measures of mammographic density were measured using computer-assisted software. General linear models were used to assess the association between lifestyle factors and mammographic density and effect modification by body mass index (BMI) and HRT was studied. Results Overall, alcohol intake was positively associated with percent mammographic density (P trend  = 0.07). This association was modified by HRT use (P interaction  = 0.06): increasing alcohol intake was associated with increasing percent density in current HRT users (P trend  = 0.01) but not in non-current users (P trend  = 0.82). A similar interaction between alcohol and HRT was found for the absolute dense area, with a positive association being present in current HRT users only (P interaction  = 0.04). No differences in mammographic density were observed across categories of smoking and physical activity, neither overall nor in stratified analyses by BMI and HRT use. Conclusions Increasing alcohol intake is associated with an increase in mammography density, whereas smoking and physical activity do not seem to influence density. The observed interaction between alcohol and HRT may pose an opportunity for HRT users to lower their mammographic density and breast cancer risk. PMID:24349146

  18. Prevalence and potential influencing factors of non-nutritive oral behaviors of veal calves on commercial farms.

    PubMed

    Leruste, H; Brscic, M; Cozzi, G; Kemp, B; Wolthuis-Fillerup, M; Lensink, B J; Bokkers, E A M; van Reenen, C G

    2014-11-01

    Veal calves raised under intensive conditions may express non-nutritive oral behaviors. When expressed in an abnormal way, these behaviors can be a sign of mental suffering and reduced welfare due to a mismatch between environmental or management features and the animal's needs. The aims of this study were to estimate the prevalence of non-nutritive oral behaviors in a large sample of veal farms in Europe and to determine the potential influencing factors present at farm level. Data were collected on 157 commercial veal farms in the 3 main veal-producing countries in Europe (the Netherlands, France, and Italy). Observations of 3 non-nutritive oral behaviors (manipulating substrates, tongue rolling, and manipulating a penmate) were performed when calves were aged 14 wk, and the prevalence of these behaviors was calculated. Information on management practices and characteristics of the building and equipment were collected on all farms to assess potential influencing factors for each of the 3 behaviors. Odds ratios and 95% confidence intervals were calculated to evaluate the effect of each individual factor within a generalized linear model. The mean percentage of calves per farm performing manipulating substrates was 11.0 ± 0.46%, performing tongue rolling 2.8 ± 0 .18%, and manipulating a penmate 2.7 ± 0.09%, with a high range between farms. Allowing more space for calves than the legal minimum requirement of 1.8 m(2)/ calf and housing them in groups of >10 calves/pen reduced the incidences of manipulating substrates and tongue rolling. Incidence of manipulating substrates was lower for calves fed maize silage compared with calves fed cereal grain, pellets, or muesli. A higher risk of tongue rolling was found when baby-boxes (i.e., single housing during the first 5 to 8 wk) were not used. Risk of calves manipulating a penmate was higher for calves of milk- or meat-type breeds compared with dual-purpose breeds and for calves fed with 280 to 380 kg compared with

  19. Influence of factors on mammographic density in premenopausal Chinese women.

    PubMed

    Yang, Yaping; Liu, Jieqiong; Gu, Ran; Hu, Yue; Liu, Fengtao; Yun, Miaomiao; Xiao, Qiaozhen; Wu, Mei; Liu, Qiang; Su, Fengxi

    2016-07-01

    Mammographic density is an independent strong risk factor for breast cancer. However, the influence of factors on mammographic density in premenopausal women remains unclear. In the Southern Professional Women Breast Cancer Screening Project, we assessed the associations between mammographic density and its influential factors using multivariate logistic regression in premenopausal women adjusting for BMI, age, duration of breastfeeding, number of live births, and breast size. A total of 1699 premenopausal women aged 27 to 57 years, who had been screened by mammography, were enrolled in this cross-sectional study. Overall, 85.2% were categorized as having dense breasts (BI-RADS density 3 and 4) and 14.8% as having fatty breasts (BI-RADS density 1 and 2). In multivariate and logistic regression analysis, only BMI and age were significantly negatively correlated with mammographic density in premenopausal women (P<0.001). No significant associations between mammographic density and number of deliveries, breastfeeding duration, education level, family history of breast cancer, as well as breast size and sleep quality, were identified in the study. Age and BMI are negatively associated with mammographic density in premenopausal Chinese women. Information on the influential factors of mammographic density in premenopausal women might provide meaningful insights into breast cancer prevention. PMID:26075657

  20. Influencing factors of hydrogen bonding intensity in beer.

    PubMed

    Liu, Chunfeng; Dong, Jianjun; Yin, Xiangsheng; Li, Qi; Gu, Guoxian

    2014-11-01

    The hydrogen bonding was prone to be formed by many components in beer. Different sorts of flavor substances can affect the Chemical Shift due to their different concentrations in beer. Several key factors including 4 alcohols, 2 esters, 6 ions, 9 acids, 7 polyphenols, and 2 gravity indexes (OG and RG) were determined in this research. They could be used to investigate the relationship between hydrogen bonding intensity and the flavor components in bottled larger beers through the Correlation Analysis, Principal Component Analysis and Multiple Regression Analysis. Results showed that ethanol content was the primary influencing factor, and its correlation coefficient was 0.629 for Correlation Analysis. Some factors had a positive correlation with hydrogen bonding intensity, including the content of original gravity, ethanol, isobutanol, Cl(-), K(+), pyruvic acid, lactic acid, gallic acid, vanillic acid, and Catechin in beer. A mathematic model of hydrogen bonding Chemical Shift and the content of ethanol, pyruvic acid, K(+), and gallic acid was obtained through the Principal Component Analysis and Multiple Regression Analysis , with the adjusted R(2) being 0.779 (P = 0.001). Ethanol content was proved to be the most important factor which could impact on hydrogen bonding association in beer by Principal Component Analysis. And then, a multiple non-linearity model could be obtained as follows: [Formula: see text]. The average error was 1.23 % in the validated experiment. PMID:26396290

  1. Factors influencing pharmacists' selection of their first practice setting.

    PubMed

    Carter, E A; Segal, R

    1989-11-01

    Factors that influenced the choice of initial practice setting among pharmacists who had completed the majority of their experiential training in a hospital setting were determined. A questionnaire was mailed to all eligible pharmacists who successfully completed the Ohio pharmacist licensure examination in June or September 1987. Respondents were asked to (1) provide demographic data, (2) rate the importance of 23 factors that a pharmacist might consider when choosing a practice site, and (3) rate the desirability of a pharmacist position in their major hospital internship site, as well as positions they had considered in other hospitals and in community pharmacies. The predictive accuracy of four decision-making models--the weighted compensatory choice model, the unweighted compensatory choice model, the lexicographic model, and the conjunctive model--also was determined. Of 105 pharmacists surveyed, 53 returned usable questionnaires. Twenty-five had chosen to practice in hospital settings, and 28 had chosen community settings. The factor "is personally rewarding" was mentioned most often by hospital and community pharmacists as the factor that was most important when choosing their first position. The lexicographic model, which postulates that a pharmacist will choose the practice site with the highest performance rating for the most important factor, was the most accurate predictor of respondents' initial practice sites. Pharmacists' perception of how practice sites would rate in terms of the single job-related factor most important to them was the best predictor of whether they chose hospital or community practice initially and whether they chose to work in the hospital in which they served their internship, another hospital, or a community pharmacy. PMID:2589346

  2. Computer visualizations: factors that influence spatial anatomy comprehension.

    PubMed

    Nguyen, Ngan; Nelson, Andrew J; Wilson, Timothy D

    2012-01-01

    Computer visualizations are increasingly common in education across a range of subject disciplines, including anatomy. Despite optimism about their educational potential, students sometime have difficulty learning from these visualizations. The purpose of this study was to explore a range of factors that influence spatial anatomy comprehension before and after instruction with different computer visualizations. Three major factors were considered: (1) visualization ability (VZ) of learners, (2) dynamism of the visual display, and (3) interactivity of the system. Participants (N = 60) of differing VZs (high, low) studied a group of anatomical structures in one of three visual conditions (control, static, dynamic) and one of two interactive conditions (interactive, non-interactive). Before and after the study phase, participants' comprehension of spatial anatomical information was assessed using a multiple-choice spatial anatomy task (SAT) involving the mental rotation of the anatomical structures, identification of the structures in 2D cross-sections, and localization of planes corresponding to given cross-sections. Results indicate that VZ had a positive influence on SAT performance but instruction with different computer visualizations could modulate the effect of VZ on task performance. PMID:22232125

  3. In-hospital resuscitation: opioids and other factors influencing survival

    PubMed Central

    Fecho, Karamarie; Jackson, Freeman; Smith, Frances; Overdyk, Frank J

    2009-01-01

    Purpose: “Code Blue” is a standard term used to alertt hospital staff that a patient requires resuscitation. This study determined rates of survival from Code Blue events and the role of opioids and other factors on survival. Methods: Data derived from medical records and the Code Blue and Pharmacy databases were analyzed for factors affecting survival. Results: During 2006, rates of survival from the code only and to discharge were 25.9% and 26.4%, respectively, for Code Blue events involving cardiopulmonary resuscitation (CPR; N = 216). Survival rates for events not ultimately requiring CPR (N = 77) were higher, with 32.5% surviving the code only and 62.3% surviving to discharge. For CPR events, rates of survival to discharge correlated inversely with time to chest compressions and defibrillation, precipitating event, need for airway management, location and age. Time of week, witnessing, postoperative status, gender and opioid use did not influence survival rates. For non-CPR events, opioid use was associated with decreased survival. Survival rates were lowest for patients receiving continuous infusions (P < 0.01) or iv boluses of opioids (P < 0.05). Conclusions: One-quarter of patients survive to discharge after a CPR Code Blue event and two-thirds survive to discharge after a non-CPR event. Opioids may influence survival from non-CPR events. PMID:20057895

  4. Biology, Genetics, and Environment: Underlying Factors Influencing Alcohol Metabolism.

    PubMed

    Wall, Tamara L; Luczak, Susan E; Hiller-Sturmhöfel, Susanne

    2016-01-01

    Gene variants encoding several of the alcohol-metabolizing enzymes, alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH), are among the largest genetic associations with risk for alcohol dependence. Certain genetic variants (i.e., alleles)--particularly the ADH1B*2, ADH1B*3, ADH1C*1, and ALDH2*2 alleles--have been associated with lower rates of alcohol dependence. These alleles may lead to an accumulation of acetaldehyde during alcohol metabolism, which can result in heightened subjective and objective effects. The prevalence of these alleles differs among ethnic groups; ADH1B*2 is found frequently in northeast Asians and occasionally Caucasians, ADH1B*3 is found predominantly in people of African ancestry, ADH1C*1 varies substantially across populations, and ALDH2*2 is found almost exclusively in northeast Asians. Differences in the prevalence of these alleles may account at least in part for ethnic differences in alcohol consumption and alcohol use disorder (AUD). However, these alleles do not act in isolation to influence the risk of AUD. For example, the gene effects of ALDH2*2 and ADH1B*2 seem to interact. Moreover, other factors have been found to influence the extent to which these alleles affect a person's alcohol involvement, including developmental stage, individual characteristics (e.g., ethnicity, antisocial behavior, and behavioral undercontrol), and environmental factors (e.g., culture, religion, family environment, and childhood adversity). PMID:27163368

  5. Identification of the influencing factors on groundwater drought in Bangladesh

    NASA Astrophysics Data System (ADS)

    Touhidul Mustafa, Syed Md.; Huysmans, Marijke

    2015-04-01

    Groundwater drought is a specific type of drought that concerns groundwater bodies. It may have a significant adverse effect on the socio-economic, agricultural, and environmental conditions. Investigating the effect of response different climatic and manmade factors on groundwater drought provides essential information for sustainable planning and management of water resources. The aim of this study is to identify the influencing factors on groundwater drought in a drought prone region in Bangladesh to understand the forcing mechanisms. The Standardised Precipitation Index (SPI) and Reconnaissance Drought Index (RDI) have been used to quantify the aggregated deficit between precipitation and the evaporative demand of the atmosphere. The influence of land use patterns on the groundwater drought has been identified by calculating spatially distributed groundwater recharge as a function of land use. The result shows that drought intensity is more severe during the dry season (November to April) compared to the rainy season (May to October). The evapotranspiration and rainfall deficit has a significant effect on meteorological drought which has a direct relation with groundwater drought. Urbanization results in a decrease of groundwater recharge which increases groundwater drought severity. Overexploitation of groundwater for irrigation and recurrent meteorological droughts are the main causes of groundwater drought in the study area. Efficient irrigation management is essential to reduce the growing pressure on groundwater resources and ensure sustainable water management. More detailed studies on climate change and land use change effects on groundwater drought are recommended. Keywords: Groundwater drought, SPI & RDI, Spatially distributed groundwater recharge, Irrigation, Bangladesh

  6. Environmental Factors Influencing Arctic Halogen Chemistry During Late Spring

    NASA Astrophysics Data System (ADS)

    Burd, J.; Nghiem, S. V.; Simpson, W. R.

    2015-12-01

    Reactive halogen radicals (e.g. Br, Cl atoms and their oxides, BrO, ClO) are important oxidizers in the troposphere that decrease atmospheric pollutants and deplete tropospheric ozone, affecting the abundance of other oxidizers such as the hydroxyl radical. During Arctic springtime, the heterogeneous chemical cycles (often called the "bromine explosion") produce high levels of bromine monoxide (BrO), through reactions on saline snow, ice, and/or aerosol surfaces. Multi-AXis Differential Optical Absorption Spectroscopy (MAX-DOAS) measured BrO at Barrow, AK, from 2008-2009 and 2012-2015, as well at various locations above the frozen Arctic Ocean with O-Buoys in 2008 and 2011-2015. Observed BrO levels drop suddenly during late spring (May-June) and generally do not recover, which indicates the bromine explosion cycle can no longer produce significant amounts of BrO. We have established, through an objective algorithm, the local day of year of this drop in BrO as the "seasonal end." Additionally, in about half of the years, "recurrence" events were observed where BrO levels recover for at least a day. This study investigates the environmental factors influencing seasonal end and recurrence events including: temperature, relative humidity, precipitation and snowmelt. Analysis of BrO and air temperature revealed the temperature reaches 0°C within five days of the seasonal end event; however, temperatures drop below freezing during a recurrence event. In addition, there are periods where the temperature remains below freezing, but no recurrence event is observed. This BrO and temperature analysis indicates above-freezing air temperature prevents reactive bromine release; however, it is not the only environmental factor influencing this heterogeneous recycling. Further analysis of additional environmental influences on the bromine explosion cycle could help to better understand and model bromine chemistry in the Arctic.

  7. Chocolate Milk Consequences: A Pilot Study Evaluating the Consequences of Banning Chocolate Milk in School Cafeterias

    PubMed Central

    Hanks, Andrew S.; Just, David R.; Wansink, Brian

    2014-01-01

    Objectives Currently, 68.3% of the milk available in schools is flavored, with chocolate being the most popular (61.6% of all milk). If chocolate milk is removed from a school cafeteria, what will happen to overall milk selection and consumption? Methods In a before-after study in 11 Oregon elementary schools, flavored milk–which will be referred to as chocolate milk–was banned from the cafeteria. Milk sales, school enrollment, and data for daily participation in the National School Lunch Program (NSLP) were compared year to date. Results Total daily milk sales declined by 9.9% (p<0.01). Although white milk increased by 161.2 cartons per day (p<0.001), 29.4% of this milk was thrown away. Eliminating chocolate milk was also associated with 6.8% fewer students eating school lunches, and although other factors were also involved, this is consistent with the notion of psychological reactance. Conclusions Removing chocolate milk from school cafeterias may reduce calorie and sugar consumption, but it may also lead students to take less milk overall, drink less (waste more) of the white milk they do take, and no longer purchase school lunch. Food service managers need to carefully weigh the costs and benefits of eliminating chocolate milk and should consider alternative options that make white milk more convenient, attractive, and normal to choose. PMID:24740451

  8. Paratuberculosis: decrease in milk production of German Holstein dairy cows shedding Mycobacterium avium ssp. paratuberculosis depends on within-herd prevalence.

    PubMed

    Donat, K; Soschinka, A; Erhardt, G; Brandt, H R

    2014-05-01

    Paratuberculosis impairs productivity of infected dairy cows because of reduced milk production and fertility and enhanced risk of culling. The magnitude of the milk yield depression in individual cows is influenced by factors such as parity, the stage of the disease and the choice of test used. The objectives of this case-control study were to substantiate the influence of the different levels of the within-herd prevalence (WHP) on individual milk yield of fecal culture (FC)-positive cows (FC+) compared with FC-negative herd-mates (FC-), and to estimate the magnitude of the deviation of the milk yield, milk components and somatic cell count (SCC) in an FC-based study. Of a total of 31 420 cows from 26 Thuringian dairy herds tested for paratuberculosis by FC, a subset of 1382 FC+ and 3245 FC- with milk recording data were selected as cases and controls, respectively. The FC- cows were matched for the same number and stage of lactation (±10 days in milk) as one FC+ from the same herd. Within a mixed model analysis using the fixed effects of Mycobacterium avium ssp. paratuberculosis (MAP) status, lactation number, days in milk, prevalence class of farm and the random effect of farm on milk yield per day (kg), the amount of fat and protein (mg/dl) and lactose (mg/dl) as well as the SCC (1000/ml) were measured. On the basis of least square means, FC+ cows had a lower test-day milk yield (27.7±0.6 kg) compared with FC- (29.0±0.6 kg), as well as a lower milk protein content and a slightly diminished lactose concentration. FC status was not associated with milk fat percentage or milk SCC. In FC+ cows, reduction in milk yield increased with increasing WHP. An interaction of FC status and farm was found for the test-day milk yield, and milk protein percentage, respectively. We conclude that the reduction in milk yield of FC+ cows compared with FC- herd-mates is significantly influenced by farm effects and depends on WHP class. Owners of MAP-positive dairy herds may

  9. The effect of pre-milking teat-brushing on milk processing time in an automated milking system.

    PubMed

    Jago, Jenny G; Davis, Kendra L; Copeman, Peter J; Woolford, Murray M

    2006-05-01

    Cow throughput in an automatic milking system (AMS) is limited by system parameters such as the time required for pre-milking udder preparation and cup attachment, physiological responses of the cow (such as milk let-down and milking-out rate), milking machine features and cow behaviour. A single-factor cross-over design was used to investigate the effect of pre-milking teat brushing on milk processing time in an AMS operating in an extensive grazing farming system. Teat brushing consisted of two roller brushes tracking up each teat three times (total brushing time of up to 45 s/cow). Cows were allocated to one of two treatment groups with either no brushing (NB) or brushing (B) for a 4-week period before being changed to the other treatment. Teat brushing resulted in shorter average cups-on-time (B = 506.1 s, NB = 541.0 s, P = 0.0001), longer average milk processing time (B = 10.30 min, NB = 9.76 min, P = 0.001) and no difference in daily milk yield (B = 14.67, NB = 14.71 kg/cow, P = 0.826). There was no difference between the two treatments in the success of cup attachment (B = 3.76%, NB = 5.10% unsuccessful milking attempts, P = 0.285). The estimated time cost of pre-milking teat brushing was 53 min for every 100 milkings, equivalent to an additional 5-6 milkings for every 100 milkings by an AMS. The importance of these potential time savings is discussed in relation to automatic milking in farming systems that aim for a lower per cow milking frequency and high ratio of cows to AMS. PMID:16476173

  10. Diverse influences of dietary factors on cancer in Asia.

    PubMed

    Moore, Malcolm A

    2009-01-01

    The major environmental risk factors for cancer are carcinogen and co-carcinogen exposure in tobacco, insufficient exercise and above all an unhealthy diet. What we eat or do not eat is exceedingly important in determining what cancers or other chronic disease we may suffer from. Carcinogens may be integral contaminants of the diet, like nitrosamines in some situations and aflatoxins, or may be generated by cooking processes, as is known to be the case for heterocyclic amine pyrolysis products. Examples of co-carcinogenic agents may include grit in bread products, salt in pickles or betel in chewing quids. Dietary insufficiencies, for example of zinc, may also act to increase sensitivity to genetic damage, for example. Influence on metabolism of carcinogens, like induction of phase II enzymes like glutathione S transferases, further directly impacts on carcinogenicity. Antioxidants in fruits and vegetables are typical examples of protective agents acting in this way. In addition we have dietary fibre which can decrease carcinogen exposure through accelerating passage of faeces through the gut. Other types of fibre, the soluble forms, can act to decrease uptake of glucose and thus suppress insulin exposure, an important factor for colon cancer. Natural anti-inflammatory agents like N-3 fatty acids in fish offer another example of preventive factors in the diet. Individual dietary components, like isoflavones in soy products, can interfere with hormone function to exert a beneficial action, as on the breast. Other compounds may act via stimulation of the immune system like lactoferrin and betaglucans. Perhaps the most important influence of diet on cancer, however, in a world of increasing comfort and ease of access to foodstuffs, is through over-eating and consequent obesity. Given the importance of diet to all our lives, we need to focus on all possible interactive effects in providing an evidence base to guide our choices regarding what we should eat in Asia. PMID

  11. Academic, social and cultural factors influencing medical school grade performance.

    PubMed

    Alfayez, S F; Strand, D A; Carline, J D

    1990-05-01

    Studies of medical student performance have focused on various factors, including premedical academics, maturity, familial background and support, and personal experiences with illness. Most studies have been conducted in countries with highly developed educational systems and similar cultural and social systems. It is not clear that these findings can be applied to developing countries, where the educational and cultural experiences may be very different, and where medical instruction is carried out in a non-native language. Information was obtained from a survey of 153 fifth- and sixth-year medical students at King Abdulaziz University in Saudi Arabia. The survey measured premedical educational, social and cultural experiences that might affect medical school performance. Men performed as well as women in the medical school despite heavy familial and social commitments. Women's performance seems to be more influenced by changes in living environment. Achievement in premedical years was correlated positively with grade performance in medical school. Competence in the high-school English courses was related to medical school performance. Interest in the study of medicine prior to medical school was not related to performance. Other motivations, such as social gains, financial benefits or family wish, were related to lower performance. Current interest in clinical medicine correlated negatively with performance. Students motivated by the presence of chronic ill health in their families performed significantly lower. Factors influencing medical school performance in developed countries had similar impact on medical students in a developing country. Social factors, unique to the country, also play a role in medical student performance. PMID:2355866

  12. Nutritional stimulation of milk protein yield of cows is associated with changes in phosphorylation of mammary eukaryotic initiation factor 2 and ribosomal s6 kinase 1.

    PubMed

    Toerien, Chanelle A; Trout, Donald R; Cant, John P

    2010-02-01

    Production of protein by the lactating mammary gland is stimulated by intake of dietary energy and protein. Mass-action effects of essential amino acids (EAA) cannot explain all of the nutritional response. Protein synthesis in tissues of growing animals is regulated by nutrients through the mammalian target of rapamycin (mTOR) and integrated stress response (ISR) networks. To explore if nutrients signal through the mTOR and ISR networks in the mammary gland in vivo, lactating cows were feed-deprived for 22 h and then infused i.v. for 9 h with EAA+ glucose (Glc), Glc only, l-Met+l-Lys, l-His, or l-Leu. Milk protein yield was increased 33 and 27% by EAA+Glc and Glc infusions, respectively. Infusions of Met+Lys and His generated 35 and 41%, respectively, of the EAA+Glc response. Infusion of EAA+Glc reduced phosphorylation of the ISR target, eukaryotic initiation factor(eIF) 2, in mammary tissue and increased phosphorylation of the mTOR targets, ribosomal S6 kinase 1 (S6K1) and S6. Both responses are stimulatory to protein synthesis. Glucose did not significantly increase mammary S6K1 phosphorylation but reduced eIF2 phosphorylation by 62%, which implicates the ISR network in the stimulation of milk protein yield. In contrast, the EAA infusions increased (P < 0.05) or tended to increase (P < 0.1) mammary mTOR activity and only His, like Glc, decreased eIF2 phosphorylation by 62%. Despite activation of these protein synthesis signals to between 83 and 127% of the EAA+Glc response, EAA infusions produced less than one-half of the milk protein yield response generated by EAA+Glc, indicating that ISR and mTOR networks exert only a portion of the control over protein yield. PMID:20032484

  13. Mountain cold-trapping increases transfer of persistent organic pollutants from atmosphere to cows' milk.

    PubMed

    Shunthirasingham, Chubashini; Wania, Frank; MacLeod, Matthew; Lei, Ying Duan; Quinn, Cristina L; Zhang, Xianming; Scheringer, Martin; Wegmann, Fabio; Hungerbühler, Konrad; Ivemeyer, Silvia; Heil, Fritz; Klocke, Peter; Pacepavicius, Grazina; Alaee, Mehran

    2013-08-20

    Concentrations of long-lived organic contaminants in snow, soil, lake water, and vegetation have been observed to increase with altitude along mountain slopes. Such enrichment, called "mountain cold-trapping", is attributed to a transition from the atmospheric gas phase to particles, rain droplets, snowflakes, and Earth's surface at the lower temperatures prevailing at higher elevations. Milk sampled repeatedly from cows that had grazed at three different altitudes in Switzerland during one summer was analyzed for a range of persistent organic pollutants. Mountain cold-trapping significantly increased air-to-milk transfer factors of most analytes. As a result, the milk of cows grazing at higher altitudes was more contaminated with substances that have regionally uniform air concentrations (hexachlorobenzene, α-hexachlorocyclohexane, endosulfan sulfate). For substances that have sources, and therefore higher air concentrations, at lower altitudes (polychlorinated biphenyls, γ-hexachlorocyclohexane), alpine milk has lower concentrations, but not as low as would be expected without mountain cold-trapping. Differences in the elevational gradients in soil concentrations and air-to-milk transfer factors highlight that cold-trapping of POPs in pastures is mostly due to increased gas-phase deposition as a result of lower temperatures causing higher uptake capacity of plant foliage, whereas cold-trapping in soils more strongly depends on wet and dry particle deposition. Climatic influences on air-to-milk transfer of POPs needs to be accounted for when using contamination of milk lipids to infer contamination of the atmosphere. PMID:23885857

  14. Effects of light and copper ions on volatile aldehydes of milk and milk fractions

    SciTech Connect

    Jeno, W.; Bassette, R.; Crang, R.E.

    1988-09-01

    Raw, laboratory-pasteurized and plant-pasteurized homogenized milks were exposed to copper ions (5 ppm), to sunlight or fluorescent light and the effects determined on the composition of volatile aldehydes. The greatest change due to copper treatment was an increase in n-hexanal; acetaldehyde showed the least response in each of the sources of milk. The responses were similar from all three sources of milk with laboratory-pasteurized milk samples showing the greatest responses for each aldehyde analyzed. Similar milk samples exposed to sunlight also showed an increase in volatile aldehydes from all milk sources but with the greatest response being acetaldehyde and n-pentanal components. The milk fraction most susceptible to changes in the presence of light was neutralized whey, whereas resuspended cream was most susceptible to copper exposure. Overall, dialyzed whey appeared to be influenced more than other milk fractions by both light and copper ions.

  15. Risk Factors Influencing Smoking Behavior: A Turkish Twin Study

    PubMed Central

    Öncel, Sevgi Yurt; Dick, Danielle M.; Maes, Hermine H.; Alıev, Fazil

    2015-01-01

    Aim In this study, we introduce the first twin study in Turkey, focusing on smoking behavior, and laying the foundation to register all twins born in Turkey for research purposes. Using Turkish twins will contribute to our understanding of health problems in the context of cultural differences. Materials and methods We assessed 309 twin pairs (339 males and 279 females) aged between 15 and 45 years living in the Kırıkkale and Ankara regions of Turkey, and administered a health and lifestyle interview that included questions about smoking status and smoking history. We analyzed the data using descriptive statistics, t-tests, chi-square tests, and bivariate and multivariate clustered logistic regression. In addition, we fit bivariate Structural Equation Models (SEM) to determine contributions of latent genetic and environmental factors to smoking outcomes in this sample. Results One hundred seventy-eight participants (28.8%) were identified as smokers, smoking every day for a month or longer, of whom 79.2% were males and 20.8% were females. Mean values for number of cigarettes per day and the Fagerstrom Test of Nicotine Dependence (FTND; Fagerstrom, 1978) score were higher in males than in females, and age of onset was earlier in males. There was a significant positive correlation between the FTND score and number of cigarettes smoked per day, and a significant negative correlation between both variables and age at onset of smoking. Our study showed that gender, presence of a smoking twin in the family, age, alcohol use, marital status, daily sports activities, and feeling moody all played a significant role in smoking behavior among twins. The twin analysis suggested that 79.5% of the liability to FTND was influenced by genetic factors and 20.5% by unique environment, while familial resemblance for smoking initiation was best explained by common environmental factors. Conclusions Marked differences in the prevalence of smoking behavior in men versus women were

  16. Abiotic environmental factors influencing blowfly colonisation patterns in the field.

    PubMed

    George, Kelly A; Archer, Melanie S; Toop, Tes

    2013-06-10

    The accuracy of minimum post-mortem interval (mPMI) estimates usually hinges upon the ability of forensic entomologists to predict the conditions under which calliphorids will colonise bodies. However, there can be delays between death and colonisation due to poorly understood abiotic and biotic factors, hence the need for a mPMI. To quantify the importance of various meteorological and light-level factors, beef liver baits were placed in the field (Victoria, Australia) on 88 randomly selected days over 3 years in all seasons and observed every 60-90 min for evidence of colonisation. Baits were exposed during daylight, and the following parameters were measured: barometric pressure, light intensity, wind speed, ambient temperature, relative humidity and rainfall. Collected data were analysed using backward LR logistic regression to produce an equation of colonisation probability. This type of analysis removes factors with the least influence on colonisation in successive steps until all remaining variables significantly increase the accuracy of predicting colonisation presence or absence. Ambient temperature was a positive predictor variable (an increase in temperature increased the probability of calliphorid colonisation). Relative humidity was a negative predictor variable (an increase in humidity decreased the probability of calliphorid colonisation). Barometric pressure, light intensity, wind speed and rainfall did not enhance the accuracy of the probability model; however, analysis of species activity patterns suggests that heavy rainfall and strong wind speeds inhibit calliphorid colonisation. PMID:23683914

  17. Patient risk factors' influence on survival of posterior composites.

    PubMed

    van de Sande, F H; Opdam, N J; Rodolpho, P A Da Rosa; Correa, M B; Demarco, F F; Cenci, M S

    2013-07-01

    This practice-based retrospective study evaluated the survival of resin composite restorations in posterior teeth, focusing on the influence of potential patient risk factors. In total, 306 posterior composite restorations placed in 44 adult patients were investigated after 10 to 18 yrs. The history of each restoration was extracted from the dental records, and a clinical evaluation was performed with those still in situ. The patient risk status was assessed for caries and "occlusal-stress" (bruxism-related). Statistical analysis was performed by the Kaplan-Meier method and Cox-regression multivariate analysis. In total, 30% of the restorations failed, of which 82% were found in patients with 1 or 2 risk factors. Secondary caries was the main reason of failure within caries-risk patients, whereas fracture was the main reason in "occlusal-stress-risk" patients. The patient variables gender and age did not significantly affect survival, but risk did (p < .001). Tooth type (p < .001), arch (p = .013), and pulpal vitality (p = .003) significantly affected restoration survival. Within the limits of this retrospective evaluation, the survival of restorations is affected by patient risk factors, which should be included in survival analyses of restorations. PMID:23690354

  18. Perceptual factors that influence use of computer enhanced visual displays

    NASA Technical Reports Server (NTRS)

    Littman, David; Boehm-Davis, Debbie

    1993-01-01

    This document is the final report for the NASA/Langley contract entitled 'Perceptual Factors that Influence Use of Computer Enhanced Visual Displays.' The document consists of two parts. The first part contains a discussion of the problem to which the grant was addressed, a brief discussion of work performed under the grant, and several issues suggested for follow-on work. The second part, presented as Appendix I, contains the annual report produced by Dr. Ann Fulop, the Postdoctoral Research Associate who worked on-site in this project. The main focus of this project was to investigate perceptual factors that might affect a pilot's ability to use computer generated information that is projected into the same visual space that contains information about real world objects. For example, computer generated visual information can identify the type of an attacking aircraft, or its likely trajectory. Such computer generated information must not be so bright that it adversely affects a pilot's ability to perceive other potential threats in the same volume of space. Or, perceptual attributes of computer generated and real display components should not contradict each other in ways that lead to problems of accommodation and, thus, distance judgments. The purpose of the research carried out under this contract was to begin to explore the perceptual factors that contribute to effective use of these displays.

  19. Factors influencing teaching style in block-scheduled science classrooms

    NASA Astrophysics Data System (ADS)

    Schoen Giddings, Linda

    This survey study sought to determine the extent to which teachers' personal belief systems, the leadership practices of the principal, and the nature of the organization as a professional learning community influence their teaching methodologies. The data were contributed by 172 South Carolina science teachers from 65 4 x 4 block-scheduled high schools. The teachers were pre-identified by teaching style as predominantly constructivist or traditional. The online survey consisted of two parts. Part I was the CTBA (Torff & Warburton 2005), which examined teacher beliefs regarding critical-thinking classroom strategies. Part II was the short form of the LOLSO Project Questionnaires (Shins et al., 2002), which examined teacher perceptions of their principal as a transformational leader and of their school as a learning organization. Logistic regression analysis identified two significant factors differentiating constructivist and traditional teachers. Traditional teachers were more likely to believe that low critical-thinking strategies were appropriate strategies for use in the classroom and constructivist teachers were more likely to perceive their schools as learning organizations. These two factors, when entered into the logistic regression predictive equation, could predict group membership with a 61% accuracy level. While not a differentiating factor, there was also a strong correlation between leadership and organizational learning (r = .86). These findings are consistent with other research that has found that schools which are learning organizations support more constructivist pedagogy and student-centered classrooms and are dependent upon strong support from school leadership.

  20. Factors influencing the stream-aquifer flow exchange coefficient.

    PubMed

    Morel-Seytoux, Hubert J; Mehl, Steffen; Morgado, Kyle

    2014-01-01

    Knowledge of river gain from or loss to a hydraulically connected water table aquifer is crucial in issues of water rights and also when attempting to optimize conjunctive use of surface and ground waters. Typically in groundwater models this exchange flow is related to a difference in head between the river and some point in the aquifer, through a "coefficient." This coefficient has been defined differently as well as the location for the head in the aquifer. This paper proposes a new coefficient, analytically derived, and a specific location for the point where the aquifer head is used in the difference. The dimensionless part of the coefficient is referred to as the SAFE (stream-aquifer flow exchange) dimensionless conductance. The paper investigates the factors that influence the value of this new conductance. Among these factors are (1) the wetted perimeter of the cross-section, (2) the degree of penetration of the cross-section, and (3) the shape of the cross-section. The study shows that these factors just listed are indeed ordered in their respective level of importance. In addition the study verifies that the analytical correct value of the coefficient is matched by finite difference simulation only if the grid system is sufficiently fine. Thus the use of the analytical value of the coefficient is an accurate and efficient alternative to ad hoc estimates for the coefficient typically used in finite difference and finite element methods. PMID:24010703

  1. Social and ecological factors influencing offspring survival in wild macaques

    PubMed Central

    Kerhoas, Daphne; Perwitasari-Farajallah, Dyah; Agil, Muhammad; Widdig, Anja

    2014-01-01

    Premature loss of offspring decreases direct fitness of parents. In gregarious mammals, both ecological and social variables impact offspring survival and may interact with each other in this regard. Although a number of studies have investigated factors influencing offspring loss in mammals, we still know very little on how different factors interact with one another. We therefore investigated fetal and infant mortality in 3 large groups of wild crested macaques (Macaca nigra) over a period of up to 5 years by including potential social causes such as maternal dominance rank, male immigration, between group encounters, and ecological conditions such as rainfall in a multivariate survival analysis using Cox proportional hazards model. Infant but not fetal survival was most impaired after a recent takeover of the alpha-male position by an immigrant male. Furthermore, infant survival probability increased when there was an increase in number of group adult females and rainfall. Fetal survival probability also increased with an increase of these 2 factors, but more in high-ranking than low-ranking females. Fetal survival, unlike that of infants, was also improved by an increase of intergroup encounter rates. Our study thus stresses the importance of survival analyses using a multivariate approach and encompassing more than a single offspring stage to investigate the determinants of female direct fitness. We further provide evidence for fitness costs and benefits of group living, possibly deriving from high pressures of both within- and between-group competition, in a wild primate population. PMID:25214754

  2. Modifiable factors influencing relapses and disability in multiple sclerosis.

    PubMed

    D'hooghe, M B; Nagels, G; Bissay, V; De Keyser, J

    2010-07-01

    A growing body of literature indicates that the natural course of multiple sclerosis can be influenced by a number of factors. Strong evidence suggests that relapses can be triggered by infections, the postpartum period and stressful life events. Vaccinations against influenza, hepatitis B and tetanus appear to be safe. Surgery, general and epidural anaesthesia, and physical trauma are not associated with an increased risk of relapses. Factors that have been associated with a reduced relapse rate are pregnancy, exclusive breastfeeding, sunlight exposure and higher vitamin D levels. A number of medications, including hormonal fertility treatment, seem to be able to trigger relapses. Factors that may worsen progression of disability include stressful life events, radiotherapy to the head, low levels of physical activity and low vitamin D levels. Strong evidence suggests that smoking promotes disease progression, both clinically and on brain magnetic resonance imaging. There is no evidence for an increased progression of disability following childbirth in women with multiple sclerosis. Moderate alcohol intake and exercise might have a neuroprotective effect, but this needs to be confirmed. PMID:20483884

  3. A compilation of radionuclide transfer factors for the plant, meat, milk, and aquatic food pathways and the suggested default values for the RESRAD code

    SciTech Connect

    Wang, Y.Y.; Biwer, B.M.; Yu, C.

    1993-08-01

    The ongoing development and revision of the RESRAD computer code at Argonne National Laboratory requires update of radionuclide transfer factors for the plant, meat, milk, and aquatic food pathways. Default values for these transfer factors used in published radiological assessment reports are compiled and compared with values used in RESRAD. The differences among the reported default values used in different radiological assessment codes and reports are also discussed. In data comparisons, values used in more recent reports are given more weight because more recent experimental work tends to be conducted under better-defined laboratory or field conditions. A new default value is suggested for RESRAD if one of the following conditions is met: (1) values used in recent reports are an order of magnitude higher or lower than the default value currently used in RESRAD, or (2) the same default value is used in several recent radiological assessment reports.

  4. Proximate and landscape factors influence grassland bird distributions

    USGS Publications Warehouse

    Cunningham, M.A.; Johnson, D.H.

    2006-01-01

    Ecologists increasingly recognize that birds can respond to features well beyond their normal areas of activity, but little is known about the relative importance of landscapes and proximate factors or about the scales of landscapes that influence bird distributions. We examined the influences of tree cover at both proximate and landscape scales on grassland birds, a group of birds of high conservation concern, in the Sheyenne National Grassland in North Dakota, USA. The Grassland contains a diverse array of grassland and woodland habitats. We surveyed breeding birds on 2015 100 m long transect segments during 2002 and 2003. We modeled the occurrence of 19 species in relation to habitat features (percentages of grassland, woodland, shrubland, and wetland) within each 100-m segment and to tree cover within 200-1600 m of the segment. We used information-theoretic statistical methods to compare models and variables. At the proximate scales, tree cover was the most important variable, having negative influences on 13 species and positive influences on two species. In a comparison of multiple scales, models with only proximate variables were adequate for some species, but models combining proximate with landscape information were best for 17 of 19 species. Landscape-only models were rarely competitive. Combined models at the largest scales (800-1600 m) were best for 12 of 19 species. Seven species had best models including 1600-m landscapes plus proximate factors in at least one year. These were Wilson's Phalarope (Phalaropus tricolor), Sedge Wren (Cistothorus platensis), Field Sparrow (Spizella pusilla), Grasshopper Sparrow (Ammodramus savannarum), Bobolink (Dolychonix oryzivorus), Red-winged Blackbird (Agelaius phoeniceus), and Brown-headed Cowbird (Molothrus ater). These seven are small-bodied species; thus larger-bodied species do not necessarily respond most to the largest landscapes. Our findings suggest that birds respond to habitat features at a variety of

  5. Proximate and landscape factors influence grassland bird distributions.

    PubMed

    Cunningham, Mary Ann; Johnson, Douglas H

    2006-06-01

    Ecologists increasingly recognize that birds can respond to features well beyond their normal areas of activity, but little is known about the relative importance of landscapes and proximate factors or about the scales of landscapes that influence bird distributions. We examined the influences of tree cover at both proximate and landscape scales on grassland birds, a group of birds of high conservation concern, in the Sheyenne National Grassland in North Dakota, USA. The Grassland contains a diverse array of grassland and woodland habitats. We surveyed breeding birds on 2015 100 m long transect segments during 2002 and 2003. We modeled the occurrence of 19 species in relation to habitat features (percentages of grassland, woodland, shrubland, and wetland) within each 100-m segment and to tree cover within 200-1600 m of the segment. We used information-theoretic statistical methods to compare models and variables. At the proximate scales, tree cover was the most important variable, having negative influences on 13 species and positive influences on two species. In a comparison of multiple scales, models with only proximate variables were adequate for some species, but models combining proximate with landscape information were best for 17 of 19 species. Landscape-only models were rarely competitive. Combined models at the largest scales (800-1600 m) were best for 12 of 19 species. Seven species had best models including 1600-m landscapes plus proximate factors in at least one year. These were Wilson's Phalarope (Phalaropus tricolor), Sedge Wren (Cistothorus platensis), Field Sparrow (Spizella pusilla), Grasshopper Sparrow (Ammodramus savannarum), Bobolink (Dolychonix oryzivorus), Red-winged Blackbird (Agelaius phoeniceus), and Brown-headed Cowbird (Molothrus ater). These seven are small-bodied species; thus larger-bodied species do not necessarily respond most to the largest landscapes. Our findings suggest that birds respond to habitat features at a variety of

  6. Clinical applications of bioactive milk components

    PubMed Central

    Newburg, David S.

    2015-01-01

    Milk represents a unique resource for translational medicine: It contains a rich pool of biologically active molecules with demonstrated clinical benefits. The ongoing characterization of the mechanistic process through which milk components promote development and immunity has revealed numerous milk-derived compounds with potential applications as clinical therapies in infectious and inflammatory disease, cancer, and other conditions. Lactoferrin is an effective antimicrobial and antiviral agent in high-risk patient populations and a potentially potent adjuvant to chemotherapy in lung cancer. Enteric nutrition formulas supplemented with transforming growth factor β, a milk cytokine, have been shown to promote remission in pediatric Crohn's disease. A number of milk glycans, including human milk oligosaccharides, show promise in preclinical studies as antimicrobial and anti-inflammatory agents. While active preclinical investigations of human milk may soon result in large-scale production of human milk molecules, bovine milk components in many instances represent a practical source of bioactive milk compounds for use in clinical trials. This review summarizes current efforts to translate the compounds derived from human and bovine milk into effective clinical therapies. These efforts suggest a common pathway for the translation of milk-derived compounds into clinical applications. PMID:26011900

  7. Clinical applications of bioactive milk components.

    PubMed

    Hill, David R; Newburg, David S

    2015-07-01

    Milk represents a unique resource for translational medicine: It contains a rich pool of biologically active molecules with demonstrated clinical benefits. The ongoing characterization of the mechanistic process through which milk components promote development and immunity has revealed numerous milk-derived compounds with potential applications as clinical therapies in infectious and inflammatory disease, cancer, and other conditions. Lactoferrin is an effective antimicrobial and antiviral agent in high-risk patient populations and a potentially potent adjuvant to chemotherapy in lung cancer. Enteric nutrition formulas supplemented with transforming growth factor β, a milk cytokine, have been shown to promote remission in pediatric Crohn's disease. A number of milk glycans, including human milk oligosaccharides, show promise in preclinical studies as antimicrobial and anti-inflammatory agents. While active preclinical investigations of human milk may soon result in large-scale production of human milk molecules, bovine milk components in many instances represent a practical source of bioactive milk compounds for use in clinical trials. This review summarizes current efforts to translate the compounds derived from human and bovine milk into effective clinical therapies. These efforts suggest a common pathway for the translation of milk-derived compounds into clinical applications. PMID:26011900

  8. Polychlorinated biphenyls (PCBs) and dichlorodiphenyl dichloroethene (DDE) in human milk: effects of maternal factors and previous lactation

    SciTech Connect

    Rogan, W.J.; Gladen, B.C.; McKinney, J.D.; Carreras, N.; Hardy, P.; Thullen, J.; Tingelstad, J.; Tully, M.

    1986-03-01

    The authors measured polychlorinated biphenyls (PCBs) and dichlorodiphenyl dichloroethene (DDE) in maternal serum, cord blood, placenta, and serial samples of breast milk from 868 women. Almost all samples of breast milk showed detectable levels of both chemicals. Overall, values for DDE in this study are within the range of those found previously, whereas those for PCBs are somewhat higher. Possible causes of variation in levels were investigated. For DDE, older women, Black women, cigarette smokers, and women who consumed sport fish during pregnancy had higher levels; only age and race showed large effects. For PCBs, older women, women who regularly drink alcohol, and primiparae had higher levels. In addition, both chemicals showed modest variation across occupational groupings. Casual exposure to a PCB spill did not result in chemical levels different from background. In general, women have higher levels in their first lactation and in the earlier samples of a given lactation, and levels decline both with time spend breast-feeding and with number of children nursed. These striking declines are presumably a measured of exposure to the child.

  9. Organizational, financial, and environmental factors influencing deans' tenure.

    PubMed

    Levin, R; Bhak, K; Moy, E; Valente, E; Griner, P F

    1998-06-01

    At a time when continuity of leadership in medical schools is most crucial, the tenures of deans continue to decrease. In the present study of factors influencing the tenures of 382 U.S. medical school deans from 1985 to 1994, the authors focused on issues that were likely to have had a greater impact on deans' tenures in recent years. They assumed that longer tenures are associated with less complex organizational factors and more stable environmental factors. Conversely, they assumed that deans and their tenures are adversely affected by an institution's declining financial health, a complex organizational structure, and a changing clinical marketplace where there is rapid growth of managed care. The authors compared the relationships between these factors and the length of deans' tenures during the ten-year period studied. Among the most important findings were the fact that schools that were less healthy financially, that had the same owner as the primary teaching hospital, and that had smaller numbers of faculty tended to have shorter dean's tenures and higher turnovers of deans. While the reason for shorter tenures of deans at schools that are less financially healthy is understandable, the effect of common ownership of the school and teaching hospital is less obvious, but perhaps the greater preoccupation of deans with the clinical enterprise in that circumstance is a significant constraint. The authors hope that the insights from their findings will be useful to future candidates for deanships in their negotiations with university officials and will help all parties reach more explicit agreements on such issues as expectations for financial performance of the medical school and the roles and relationships of the dean and the teaching hospital director. PMID:9653400

  10. Exploring Factors Influencing Smokers' Information Seeking for Smoking Cessation.

    PubMed

    Noh, Ghee-Young; Lee, Sun Young; Choi, Jounghwa

    2016-08-01

    This study addressed the factors influencing smokers' information seeking pertaining to the health risks of smoking. In particular, this study aimed to extend the risk information seeking and processing model by taking into account the role of autonomous motivations used to stimulate smokers' information-seeking behavior. The results of a Web-based survey indicated that information insufficiency was positively associated with health information-seeking behavior and that negative affective responses were positively associated with information insufficiency and health information-seeking behavior. In addition, autonomous motivations were positively associated with information insufficiency and information-seeking behavior. The results indicated that risk perception was positively related to autonomous motivations and negative affective response. Finally, informational subjective norm was positively related to autonomous motivations and negative affective responses. The implications of this study for future research are discussed. PMID:27367187

  11. [Greenhouse gas emission from reservoir and its influence factors].

    PubMed

    Zhao, Xiao-jie; Zhao, Tong-qian; Zheng, Hua; Duan, Xiao-nan; Chen, Fa-lin; Ouyang, Zhi-yun; Wang, Xiao-ke

    2008-08-01

    Reservoirs are significant sources of emissions of the greenhouse gases. Discussing greenhouse gas emission from the reservoirs and its influence factors are propitious to evaluate emission of the greenhouse gas accurately, reduce gas emission under hydraulic engineering and hydropower development. This paper expatiates the mechanism of the greenhouse gas production, sums three approaches of the greenhouse gas emission, which are emissions from nature emission of the reservoirs, turbines and spillways and downstream of the dam, respectively. Effects of greenhouse gas emission were discussed from character of the reservoirs, climate, pH of the water, vegetation growing in the reservoirs and so on. Finally, it has analyzed the heterogeneity of the greenhouse gas emission as well as the root of the uncertainty and carried on the forecast with emphasis to the next research. PMID:18839604

  12. Factors influencing mothers' decision to breastfeed in public.

    PubMed

    Hauck, Yvonne L

    2004-03-01

    Breastfeeding in public was a major theme that emerged in a previous Western Australian study that explored the maternal process of managing breastfeeding and subsequent weaning. This paper highlights the factors that influenced mothers' decisions to breastfeed in public. Confidence with breastfeeding, the ability to be discreet, the mother's body image, previous experience, age of the breastfeeding child, the audience, feelings of the partner, breastfeeding location and perceptions of societal expectations all impacted upon the decision of how to manage breastfeeding in public. Initiatives to promote a breastfeeding friendly community are briefly discussed as well as strategies that participants employed to manage their breastfeeding in public. These findings add to our knowledge on breastfeeding and have implications for how we support breastfeeding women. PMID:17004344

  13. [Influence of poor factors of airports on human health].

    PubMed

    Pochekaeva, E I

    2008-01-01

    The hygienic study conducted in Rostov-on-Don has shown that air transport and airports are important sources of physical and chemical pollution of the environment. Human health examinations served to illustrate the adverse impact of airports on the environmental and hygienic living conditions of the population. The performed studies provided the basis for purpose-oriented program to enhance the environment and to reduce morbidity rates in accordance with the National Environmental Hygiene Program. The developed algorithm of the assessment and reduction of a risk for diseases under the influence of poor factors associated with the activities of airports is designed to provide the authorities and concerned organizations with information, to make managerial decisions, and to work out health-improving measures. PMID:18509916

  14. Factors influencing burnout and job stress among military nurses.

    PubMed

    van Wijk, C

    1997-10-01

    Burnout among military nurses has been found to lead to job absenteeism, staff conflicts, and a high turnover of personnel. Factors influencing nurses working in smaller and often isolated military installations of the South African National Defence Force were investigated using a job-stress and burnout questionnaire and a semi-structured interview. Investigation focused on registration categories, geographic location, and age. It was found that the senior registration categories experienced more burnout, and nurses in isolated areas reported almost double the number of cases of burnout than nurses in larger centers. Age played a role in the very young (19-25 years) and older (40-50 years) nurses. The lack of support from supervisors, high responsibility, long working hours, and task overload were the four most common stressors reported. Some suggestions are forwarded to manage the risk of burnout among military nurses in similar situations. PMID:9339089

  15. Climatic factors influencing triatomine occurrence in Central-West Brazil

    PubMed Central

    Pereira, Joyce Mendes; de Almeida, Paulo Silva; de Sousa, Adair Vieira; de Paula, Aécio Moraes; Machado, Ricardo Bomfim; Gurgel-Gonçalves, Rodrigo

    2013-01-01

    We estimated the geographic distributions of triatomine species in Central-West Region of Brazil (CW) and analysed the climatic factors influencing their occurrence. A total of 3,396 records of 27 triatomine species were analysed. Using the maximum entropy method, ecological niche models were produced for eight species occurring in at least 20 municipalities based on 13 climatic variables and elevation. Triatoma sordida and Rhodnius neglectus were the species with the broadest geographic distributions in CW Brazil. The Cerrado areas in the state of Goiás were found to be more suitable for the occurrence of synanthropic triatomines than the Amazon forest areas in the northern part of the state of Mato Grosso. The variable that best explains the evaluated models is temperature seasonality. The results indicate that almost the entire region presents climatic conditions that are appropriate for at least one triatomine species. Therefore, it is recommended that entomological surveillance be reinforced in CW Brazil. PMID:23778666

  16. Factors Influencing Black Churches' Readiness to Address HIV.

    PubMed

    Pichon, Latrice C; Powell, Terrinieka Williams; Ogg, Siri A; Williams, Andrea L; Becton-Odum, Nicole

    2016-06-01

    This study employed a community-based participatory research approach to understand factors that influence church readiness to engage in HIV prevention and treatment activities. A convenience sample of twenty-six Black faith leaders participated in four focus groups. Data analysis was done through qualitative content analysis. Three themes emerged. First, the pastor's blessing and authority as the church's decision-maker determines readiness to engage in HIV prevention. Second, the church's purview of sexual health as part of a holistic ministry facilitates faith leader's readiness. Lastly, securing financial and human resources makes it feasible for faith leaders to implement activities. Findings suggest HIV-related stigma alone does not explain readiness to address HIV. Participants also discussed activities their churches are equipped to handle, including HIV testing events and health fairs. PMID:26345680

  17. Factors influencing equipment selection in electron beam processing

    NASA Astrophysics Data System (ADS)

    Barnard, J. W.

    2003-08-01

    During the eighties and nineties accelerator manufacturers dramatically increased the beam power available for high-energy equipment. This effort was directed primarily at meeting the demands of the sterilization industry. During this era, the perception that bigger (higher power, higher energy) was always better prevailed since the operating and capital costs of accelerators did not increase with power and energy as fast as the throughput. High power was needed to maintain per unit costs low for treatment. This philosophy runs counter to certain present-day realities of the sterilization business as well as conditions influencing accelerator selection in other electron beam applications. Recent experience in machine selection is described and factors affecting choice are presented.

  18. Factors influencing the frequency of children's consumption of soft drinks.

    PubMed

    Pettigrew, Simone; Jongenelis, Michelle; Chapman, Kathy; Miller, Caroline

    2015-08-01

    Among other focus areas, interventions designed to improve children's diets need to address key factors contributing to children's consumption of sugar-sweetened beverages. The present study employed structural equation modelling to investigate the relationship between a broad range of predictor variables and the frequency with which Australian children consume soft drinks. In total, 1302 parents of children aged 8 to 14 years responded to an online survey about their children's food consumption behaviours. Soft drink consumption frequency was primarily influenced by parents' attitudes to soft drinks, children's pestering behaviours, and perceived social norms relating to children's consumption of these products. Importantly, pestering and social norms had significant direct effects on consumption frequency in addition to indirect effects via their impact on parents' attitudes to soft drink. PMID:25953597

  19. Factors influencing the detection of beach plastic debris.

    PubMed

    Lavers, Jennifer L; Oppel, Steffen; Bond, Alexander L

    2016-08-01

    Marine plastic pollution is a global problem with considerable ecological and economic consequences. Quantifying the amount of plastic in the ocean has been facilitated by surveys of accumulated plastic on beaches, but existing monitoring programmes assume the proportion of plastic detected during beach surveys is constant across time and space. Here we use a multi-observer experiment to assess what proportion of small plastic fragments is missed routinely by observers, and what factors influence the detection probability of different types of plastic. Detection probability across the various types of plastic ranged from 60 to 100%, and varied considerably by observer, observer experience, and biological material present on the beach that could be confused with plastic. Blue fragments had the highest detection probability, while white fragments had the lowest. We recommend long-term monitoring programmes adopt survey designs accounting for imperfect detection or at least assess the proportion of fragments missed by observers. PMID:27363010

  20. Contribution to the study of staphylococcus contamination of cows' milk on a number of farms in Algiers: its impact on human health.

    PubMed

    Hamiroune, M; Berber, A; Boubekeur, S

    2014-12-01

    The authors describe a survey and screening programme for staphylococcus. The study covers 14 dairy farms in the Algiers region, from which 203 samples of cows' milk were taken for bacteriological testing. The survey results show that poor husbandry conditions are the main cause of staphylococcus in cows' milk. Staphylococcus was found in the milk of 30% of the cows sampled. These results were influenced by a variety of factors, in that: the contamination rate rose with the number of pregnancies, age, and volume of milk output of the cow, as well as the bedding thickness; the milk contamination rate was greater when milking occurred outside a milking parlour and when it was performed by machine; higher rates of staphylococcus infection were found in the milk of cows at the end of lactation, in red and white breeds, and in those with cylindricalteats. Identification of the bacteria found (staphylococcus) showed that coagulase- negative staphylococci were present in 67.21% of samples, whereas coagulase- positive staphylococci were present in only 32.79%. The average count for the latter was equal to 0.54 x 10(4) colony-forming units per ml of Staphylococcus aureus. Seventy percent of the milk analysed was free from staphylococci and most of the bacteria identified were not pathogenic to consumers (coagulase- negative staphylococci); nevertheless, consuming fresh milk still presents a degree of risk. PMID:25812225

  1. Functional Role of Milk Fat Globule-Epidermal Growth Factor VIII in Macrophage-Mediated Inflammatory Responses and Inflammatory/Autoimmune Diseases

    PubMed Central

    2016-01-01

    Inflammation involves a series of complex biological processes mediated by innate immunity for host defense against pathogen infection. Chronic inflammation is considered to be one of the major causes of serious diseases, including a number of autoimmune/inflammatory diseases, cancers, cardiovascular diseases, and neurological diseases. Milk fat globule-epidermal growth factor 8 (MFG-E8) is a secreted protein found in vertebrates and was initially discovered as a critical component of the milk fat globule. Previously, a number of studies have reported that MFG-E8 contributes to various biological functions including the phagocytic removal of damaged and apoptotic cells from tissues, the induction of VEGF-mediated neovascularization, the maintenance of intestinal epithelial homeostasis, and the promotion of mucosal healing. Recently, emerging studies have reported that MFG-E8 plays a role in inflammatory responses and inflammatory/autoimmune diseases. This review describes the characteristics of MFG-E8-mediated signaling pathways, summarizes recent findings supporting the roles of MFG-E8 in inflammatory responses and inflammatory/autoimmune diseases, and discusses MFG-E8 targeting as a potential therapeutic strategy for the development of anti-inflammatory/autoimmune disease drugs. PMID:27429513

  2. Management practices as risk factors for the presence of bulk milk antibodies to Salmonella, Neospora caninum and Leptospira interrogans serovar hardjo in Irish dairy herds.

    PubMed

    O' Doherty, E; Berry, D P; O' Grady, L; Sayers, R

    2014-06-01

    A survey of management practices in 309 Irish dairy herds was used to identify risk factors for the presence of antibodies to Salmonella, Neospora caninum and Leptospira interrogans serovar hardjo in extensively managed unvaccinated dairy herds. A previous study documented a herd-level seroprevalence in bulk milk of 49%, 19% and 86% for Salmonella, Neospora caninum and leptospira interrogans serovar hardjo, respectively in the unvaccinated proportion of these 309 herds in 2009. Association analyses in the present study were carried out using multiple logistic regression models. Herds where cattle were purchased or introduced had a greater likelihood of being positive to leptospira interrogans serovar hardjo (P<0.01) and Salmonella (P<0.01). Larger herds had a greater likelihood of recording a positive bulk milk antibody result to leptospira interrogans serovar hardjo (P<0.05). Herds that practiced year round calving were more likely to be positive to Neospora caninum (P<0.05) compared to herds with a spring-calving season, with no difference in risk between herds that practiced split calving compared to herds that practiced spring calving. No association was found between presence of dogs on farms and prevalence of Neospora caninum possibly due to limited access of dogs to infected materials including afterbirths. The information from this study will assist in the design of suitable control programmes for the diseases under investigation in pasture-based livestock systems. PMID:24661904

  3. Physical Factors Influencing Pleasant Touch during Passive Fingertip Stimulation

    PubMed Central

    Klöcker, Anne; Oddo, Calogero Maria; Camboni, Domenico; Penta, Massimo; Thonnard, Jean-Louis

    2014-01-01

    Objective Tactile explorations with the fingertips provide information regarding the physical properties of surfaces and their relative pleasantness. Previously, we performed an investigation in the active touch domain and linked several surface properties (i.e. frictional force fluctuations and net friction) with their pleasantness levels. The aim of the present study was to investigate physical factors being important for pleasantness perception during passive fingertip stimulation. Specifically we were interested to see whether factors, such as surfaces' topographies or their frictional characteristics could influence pleasantness. Furthermore, we ascertained how the stimulus pleasantness level was impacted by (i) the normal force of stimulus application (FN) and (ii) the stimulus temperature (TS). Methods and Results The right index fingertips of 22 blindfolded participants were stimulated using 27 different stimuli, which varied in average roughness (Ra) and TS. A 4-axis robot moved the stimuli horizontally under participants' fingertips with three levels of FN. The robot was equipped with force sensors, which recorded the FN and friction force (FT) during stimulation. Participants rated each stimulus according to a three-level pleasantness scale, as very pleasant (scored 0), pleasant (scored 1), or unpleasant (scored 2). These ordinal pleasantness ratings were logarithmically transformed into linear and unidimensional pleasantness measures with the Rasch model. Statistical analyses were conducted to investigate a possible link between the stimulus properties (i.e. Ra, FN, FT, and TS) and their respective pleasantness levels. Only the mean Ra and FT values were negatively correlated with pleasantness. No significant correlation was detected between FN or TS and pleasantness. Conclusion Pleasantness perception, resulting from passive fingertip stimulation, seems to be influenced by the surfaces' average roughness levels and average FT occurring during fingertip

  4. Talking about Relations: Factors Influencing the Production of Relational Descriptions.

    PubMed

    Baltaretu, Adriana; Krahmer, Emiel J; van Wijk, Carel; Maes, Alfons

    2016-01-01

    In a production experiment (Experiment 1) and an acceptability rating one (Experiment 2), we assessed two factors, spatial position and salience, which may influence the production of relational descriptions (such as "the ball between the man and the drawer"). In Experiment 1, speakers were asked to refer unambiguously to a target object (a ball). In Experiment 1a, we addressed the role of spatial position, more specifically if speakers mention the entity positioned leftmost in the scene as (first) relatum. The results showed a small preference to start with the left entity, which leaves room for other factors that could influence spatial reference. Thus, in the following studies, we varied salience systematically, by making one of the relatum candidates animate (Experiment 1b), and by adding attention capture cues, first subliminally by priming one relatum candidate with a flash (Experiment 1c), then explicitly by using salient colors for objects (Experiment 1d). Results indicate that spatial position played a dominant role. Entities on the left were mentioned more often as (first) relatum than those on the right (Experiments 1a-d). Animacy affected reference production in one out of three studies (in Experiment 1d). When salience was manipulated by priming visual attention or by using salient colors, there were no significant effects (Experiments 1c, d). In the acceptability rating study (Experiment 2), participants expressed their preference for specific relata, by ranking descriptions on the basis of how good they thought the descriptions fitted the scene. Results show that participants preferred most the description that had an animate entity as the first mentioned relatum. The relevance of these results for models of reference production is discussed. PMID:26903911

  5. Talking about Relations: Factors Influencing the Production of Relational Descriptions

    PubMed Central

    Baltaretu, Adriana; Krahmer, Emiel J.; van Wijk, Carel; Maes, Alfons

    2016-01-01

    In a production experiment (Experiment 1) and an acceptability rating one (Experiment 2), we assessed two factors, spatial position and salience, which may influence the production of relational descriptions (such as “the ball between the man and the drawer”). In Experiment 1, speakers were asked to refer unambiguously to a target object (a ball). In Experiment 1a, we addressed the role of spatial position, more specifically if speakers mention the entity positioned leftmost in the scene as (first) relatum. The results showed a small preference to start with the left entity, which leaves room for other factors that could influence spatial reference. Thus, in the following studies, we varied salience systematically, by making one of the relatum candidates animate (Experiment 1b), and by adding attention capture cues, first subliminally by priming one relatum candidate with a flash (Experiment 1c), then explicitly by using salient colors for objects (Experiment 1d). Results indicate that spatial position played a dominant role. Entities on the left were mentioned more often as (first) relatum than those on the right (Experiments 1a–d). Animacy affected reference production in one out of three studies (in Experiment 1d). When salience was manipulated by priming visual attention or by using salient colors, there were no significant effects (Experiments 1c, d). In the acceptability rating study (Experiment 2), participants expressed their preference for specific relata, by ranking descriptions on the basis of how good they thought the descriptions fitted the scene. Results show that participants preferred most the description that had an animate entity as the first mentioned relatum. The relevance of these results for models of reference production is discussed. PMID:26903911

  6. Factors Influencing Challenging Colonoscopies During Anesthesiologist-Assisted Deep Sedation

    PubMed Central

    Fabrizio, Cardin; Nadia, Minicuci; Alessandra, Andreotti; Elisa, Granziera; Carmelo, Militello

    2016-01-01

    Background/Aim: Increased demand for colon cancer screening procedures can significantly impact on routine colonoscopy management at dedicated facilities, prompting a review of the factors that can negatively affect workflow. Although potential adverse effects and impact on costs of deep sedation have been documented elsewhere, this study focuses on variables that can influence performance of colonoscopy in deep sedation and interfere with normal procedure scheduling in settings where the presence of an anesthesiologist is mandatory. Patients and Methods: We performed a cross-sectional study of the activities of a colonoscopy screening unit, applying Bayesian Network (BN) analysis, designed to assess interdependencies among variables that can affect a process in complex, multidimensional systems. The study was performed at a teaching hospital where endoscopists and anesthesiologists of varying work experience operate on a rota basis. During a six-month period, we analyzed 1485 consecutive colonoscopies performed under deep propofol sedation, administered by an anesthesiologist via hand-controlled syringe. The BN was constructed with the variables: Gender, age, ASA status, bowel preparation, baseline blood pressure, endoscopist's experience, anesthesiologist's experience, presence of polypectomy, and the target node, “challenging procedure.” This previously undefined category refers to any events disrupting the scheduled rota. Result and Conclusion: Two distinct networks were identified. One deals mainly with relationships among the variables, patients’ demographic and clinical characteristics (procedures with polypectomy, ASA and baseline blood pressure). The other explains relationships among the variables, “challenging procedure,” bowel preparation, and endoscopist's experience. The factors associated with the anesthesiologist's activity do not influence challenging colonoscopies. PMID:26831609

  7. [Factors influencing early extubation after open heart surgery].

    PubMed

    Varró, M; Gombocz, K; Wrana, G

    2001-06-10

    The authors have performed a retrospective study in order to review the occurrence and the influencing factors of early extubation among their patients. Those patients who had any severe complication in the immediate postoperative period (pericardial tamponade, low cardiac output syndrome, re-operation due to excessive bleeding, postperfusion lung syndrome, pulmonary edema) preventing early extubation, have been excluded from the study. In the remaining 690 patients early extubation within 8 hours and within 4 hours could be carried out in 525 (76.1%) and 164 cases (23.8%) respectively. Late (beyond 12 hours) extubation occurred in 68 cases (9.9%). Anaesthesia was governed by two different methods. Midazolam and alfentanyl (group 1) were used in 137 cases (19.9%) whilst 553 patients (80.1%) received propofol and alfentanyl (group 2). In group 1 and 2 early extubation was possible in 50.4 and 82.5% respectively (p < 0.0001). In further investigations 27 pre- and intraoperative variables of each patient have been studied and analysed. For statistical analysis authors used the SPSS software including T-test, Mann-Whitney-test, chi-square test and multivariate logistical regression analysis. On the basis of multivariate regression analysis factors influencing early extubation were as follows: age (B = 0.0775; p < 0.001), sex (B = 1.2900; p < 0.001), method of anaesthesia (B = 1.9753; p < 0.001), duration of anaesthesia (B = 0.0053; p < 0.001), re-do operation (B = 1.0482; p = 0.0469) and preoperative congestive heart failure (B = 0.9008; p = 0.0125). Pulmonary diseases known from patient history have not had a deep impact on early extubation. On the basis of our study early extubation has not resulted in an increased number of either the postoperative complications or the occurrence of perioperative myocardial infarction. PMID:11433920

  8. Factors influencing organic carbon preservation in marine sediments

    NASA Technical Reports Server (NTRS)

    Canfield, D. E.

    1994-01-01

    The organic matter that escapes decomposition is buried and preserved in marine sediments, with much debate as to whether the amount depends on bottom-water O2 concentration. One group argues that decomposition is more efficient with O2, and hence, organic carbon will be preferentially oxidized in its presence, and preserved in its absence. Another group argues that the kinetics of organic matter decomposition are similar in the presence and absence of O2, and there should be no influence of O2 on preservation. A compilation of carbon preservation shows that both groups are right, depending on the circumstances of deposition. At high rates of deposition, such as near continental margins, little difference in preservation is found with varying bottom-water O2. It is important that most carbon in these sediments decomposes by anaerobic pathways regardless of bottom-water O2. Hence, little influence of bottom-water O2 on preservation would, in fact, be expected. As sedimentation rate drops, sediments deposited under oxygenated bottom water become progressively more aerobic, while euxinic sediments remain anaerobic. Under these circumstances, the relative efficiencies of aerobic and anaerobic decomposition could affect preservation. Indeed, enhanced preservation is observed in low-O2 and euxinic environments. To explore in detail the factors contributing to this enhanced carbon preservation, aspects of the biochemistries of the aerobic and anaerobic process are reviewed. Other potential influences on preservation are also explored. Finally, a new model for organic carbon decomposition, the "pseudo-G" model, is developed. This model couples the degradation of refractory organic matter to the overall metabolic activity of the sediment, and has consequences for carbon preservation due to the mixing together of labile and refractory organic matter by bioturbation.

  9. Eroticization as a factor influencing erectile dysfunction treatment effectiveness.

    PubMed

    Kukula, K C; Jackowich, R A; Wassersug, R J

    2014-01-01

    We review both the medical and psychosocial literature on factors influencing male potency in order to better understand why erectile dysfunction (ED) treatments, PDE5 drugs in particular, are abandoned when otherwise effective. We incorporate anecdotal data from websites and list serves dedicated to helping patients deal with iatrogenic ED. Our goal is to distinguish between ED treatments that are medicalized versus eroticized, and how partner participation may influence their effectiveness. Recently it has been shown that ED treatment effectiveness is aided by the involvement of the patient's partner. This permits an erotic association between the partner and the ED 'aid'. We extend this idea to suggest that having the partner involved as early as possible in the discussion of treatment, and their presence at the time of prescription, should improve ED aid effectiveness. Eroticization of ED aids shifts the focus from a perceived disability of the patient toward the sexual pleasure provided by the partner. We further suggest that ED aids used without the partner's knowledge will undermine intimacy and ultimately the treatment's effectiveness. Unpartnered patients should be advised about the importance of informing potential partners about their use of such aids, as openness and honesty may increase intimacy in the long run. PMID:23823215

  10. Pediatric Organ Donation: What Factors Most Influence Parents’ Donation Decisions?

    PubMed Central

    Rodrigue, James R.; Cornell, Danielle L.; Howard, Richard J.

    2008-01-01

    Objective To identify factors that influence parents’ decisions when asked to donate a deceased child’s organs. Design Cross-sectional design with data collection via structured telephone interviews. Setting and Participants Seventy-four parents (49 donors, 25 non-donors) of donor-eligible deceased children who were previously approached by coordinators from one organ procurement organization (OPO) in the southeastern USA. Main Results Multivariate analyses showed that organ donation was more likely when the parent was a registered organ donor (OR=1.4, CI=1.1, 2.7), the parent had favorable organ donation beliefs (OR=5.5, CI=2.7, 12.3), the parent was exposed to organ donation information prior to the child’s death (OR = 2.6, CI = 1.7, 10.3), a member of the child’s healthcare team first mentioned organ donation (OR=1.4, CI=1.2, 3.7), the requestor was perceived as sensitive to the family’s needs (OR=0.4, CI=0.2, 0.7), the family had sufficient time to discuss donation (OR=5.2, CI=1.4, 11.6), and family members were in agreement about donation (OR=2.8, CI=1.3, 5.2). Conclusions This study identifies several modifiable variables that influence the donation decision-making process for parents. Strategies to facilitate targeted organ donation education and higher consent rates are discussed. PMID:18477931

  11. Factors that influence the patient centredness of a consultation.

    PubMed Central

    Law, S A; Britten, N

    1995-01-01

    BACKGROUND. Research suggests that patients are more satisfied with patient-centred consultations than with doctor-centred consultations and that some health measures are positively influenced by this type of consultation. Research on the factors that influence the patient centredness of the consultation is sparse but suggests that women doctors are more patient centred than men doctors. AIM. A study was designed, first, to confirm or reject the suggestion that women general practitioners are more patient centred than men general practitioners and, secondly, to determine some of the factors that might influence the patient centredness of a general practitioner. METHOD. The audiotaped consultations of 41 general practitioners were analysed using an instrument designed to measure patient centredness. The general practitioners were selected from a group of volunteers to represent both sexes as well as a wide range of age and experience. RESULTS. The results of the analysis showed that women general practitioners, particularly trainers, had higher patient-centredness scores than men general practitioners. This behaviour is characterized by an increased frequency of open questions and greater attention to patient offers (anything of potential significance that a patient brings to the general practitioner consultation). Additionally, the combination of sexes in a consultation seemed to have an effect on the interaction, with woman general practitioner/female patient dyads (pairings) having the highest median patient-centredness score, woman general practitioner/male patient and man general practitioner/male patient dyads scoring the same as each other and man general practitioner/female patient dyads having the lowest median scores. CONCLUSION. The results suggest that women general practitioners, in this sample, were more patient centred than men general practitioners. The results also suggest that inherent inequalities exist, with female patients receiving a more

  12. Identifying influencing factors on paved roads silt loading.

    PubMed

    Teng, Hualiang; Kwigizile, Valerian; James, David E; Merle, Russell

    2007-07-01

    The factors that influence the increase or decrease of silt loadings on paved roadways have not been fully quantitatively investigated. They were identified in this study based on the quarterly silt loading sampling data collected from 20 sites by the Clark County Department of Air Quality and Environmental Management in Southern Nevada for the period from 2000 to 2003. The silt loading and associated data collected over these years at one sampling site may inherently possess site-specific characteristics that can be better incorporated by using panel data models. The factors that are identified as significant are the presence of curbs and gutters, shoulder type, pavement conditions, and the presence of construction activities in the vicinity of roadways. The presence of curbs and gutters, stabilized shoulders, and good pavement conditions would result in decreased silt loadings. Conversely, the presence of construction activities within the immediate vicinity of sampled areas would result in increases of silt loadings on the roadway surfaces. Based on the analysis of the results, it was recommended that constructing curbs, gutters and stabilized shoulders, preventing or reducing construction track-out from construction activity, and improving pavement conditions be the preferred control measures to reduce silt loading on paved roadways. PMID:17687992

  13. Understanding the factors influencing safe and unsafe motorcycle rider intentions.

    PubMed

    Tunnicliff, Deborah J; Watson, Barry C; White, Katherine M; Hyde, Melissa K; Schonfeld, Cynthia C; Wishart, Darren E

    2012-11-01

    The increasing popularity of motorcycles in Australia is a significant concern as motorcycle riders represent 15% of all road fatalities and an even greater proportion of serious injuries. This study assessed the psychosocial factors influencing motorcycle riders' intentions to perform both safe and risky riding behaviours. Using an extended theory of planned behaviour (TPB), motorcycle riders (n=229) from Queensland, Australia were surveyed to assess their riding attitudes, subjective norm (general and specific), perceived behavioural control (PBC), group norm, self-identity, sensation seeking, and aggression, as well as their intentions, in relation to three safe (e.g., handle my motorcycle skilfully) and three risky (e.g., bend road rules to get through traffic) riding behaviours. Although there was variability in the predictors of intention across the behaviours, results revealed that safer rider intentions were most consistently predicted by PBC, while riskier intentions were predicted by attitudes and sensation seeking. The TPB was able to explain a greater proportion of the variance for intentions to perform risky behaviours. Overall, this study has provided insight into the complexity of factors contributing to rider intentions and suggests that different practical strategies need to be adopted to facilitate safer and reduce risky rider decisions. PMID:23036390

  14. Emotional and Social Factors influence Poker Decision Making Accuracy.

    PubMed

    Laakasuo, Michael; Palomäki, Jussi; Salmela, Mikko

    2015-09-01

    Poker is a social game, where success depends on both game strategic knowledge and emotion regulation abilities. Thus, poker provides a productive environment for studying the effects of emotional and social factors on micro-economic decision making. Previous research indicates that experiencing negative emotions, such as moral anger, reduces mathematical accuracy in poker decision making. Furthermore, various social aspects of the game—such as losing against "bad players" due to "bad luck"—seem to fuel these emotional states. We designed an Internet-based experiment, where participants' (N = 459) mathematical accuracy in five different poker decision making tasks were assessed. In addition, we manipulated the emotional and social conditions under which the tasks were presented, in a 2 × 2 experimental setup: (1) Anger versus neutral emotional state—participants were primed either with an anger-inducing, or emotionally neutral story, and (2) Social cue versus non-social cue—during the tasks, either an image of a pair of human eyes was "following" the mouse cursor, or an image of a black moving box was presented. The results showed that anger reduced mathematical accuracy of decision making only when participants were "being watched" by a pair of moving eyes. Experienced poker players made mathematically more accurate decisions than inexperienced ones. The results contribute to current understanding on how emotional and social factors influence decision making accuracy in economic games. PMID:24633674

  15. [Influence of genetic factors on human sexual orientation. Review].

    PubMed

    Rodríguez-Larralde, Alvaro; Paradisi, Irene

    2009-09-01

    Human sexual orientation is a complex trait, influenced by several genes, experiential and sociocultural factors. These elements interact and produce a typical pattern of sexual orientation towards the opposite sex. Some exceptions exist, like bisexuality and homosexuality, which seem to be more frequent in males than females. Traditional methods for the genetic study of behavior multifactorial characteristics consist in detecting the presence of familial aggregation. In order to identify the importance of genetic and environmental factors in this aggregation, the concordance of the trait for monozygotic and dizygotic twins and for adopted sibs, reared together and apart, is compared. These types of studies have shown that familial aggregation is stronger for male than for female homosexuality. Based on the threshold method for multifactorial traits, and varying the frequency of homosexuality in the population between 4 and 10%, heritability estimates between 0.27 and 0.76 have been obtained. In 1993, linkage between homosexuality and chromosomal region Xq28 based on molecular approaches was reported. Nevertheless, this was not confirmed in later studies. Recently, a wide search of the genome has given significant or close to significant linkage values with regions 7q36, 8p12 and 10q26, which need to be studied more closely. Deviation in the proportion of X chromosome inactivation in mothers of homosexuals seems to favor the presence of genes related with sexual orientation in this chromosome. There is still much to be known about the genetics of human homosexuality. PMID:19961060

  16. Factors influencing HIV vaccine community engagement in the urban South.

    PubMed

    Frew, Paula M; del Rio, Carlos; Clifton, Sarah; Archibald, Matthew; Hormes, Joseph T; Mulligan, Mark J

    2008-08-01

    The purpose of this exploratory study was to examine personal characteristics, socio-environmental conditions, and motivational factors that potentially influence HIV vaccine research community engagement. Specifically, the study identified predictive aspects that may aid in future community program development on HIV vaccine issues. A cross-sectional survey consisting of evaluative measures, demographics, social interaction, and health information-seeking behaviors was conducted. Participants were a diverse group of 452 adults (>or=18 years) at HIV vaccine awareness-building and community education gatherings in Atlanta. The sample included large numbers of women (n=251) and minorities (n=224). In multivariate analysis, the overall logistic regression model was significant, with a resulting coefficient of determination (Nagelkerke R(2)) of .505. Highly significant factors included an excellent activity/event rating (log odds beta = 4.521, P< .001), White race (beta= -.835, P= .005), greater educational attainment (beta= .725, P= .011), travel distance (beta = 1.186, P= .002), and excellent perception of the study site (beta=2.131, P< .001). Subgroup analyses by gender and race revealed similar findings. These data demonstrate the importance of building a favorable study site image and gaining familiarity in the community to aid in the promotion of HIV vaccine research on an ongoing basis. PMID:18389351

  17. Extrinsic Factors Influencing Fetal Deformations and Intrauterine Growth Restriction

    PubMed Central

    Moh, Wendy; Graham, John M.; Wadhawan, Isha; Sanchez-Lara, Pedro A.

    2012-01-01

    The causes of intrauterine growth restriction (IUGR) are multifactorial with both intrinsic and extrinsic influences. While many studies focus on the intrinsic pathological causes, the possible long-term consequences resulting from extrinsic intrauterine physiological constraints merit additional consideration and further investigation. Infants with IUGR can exhibit early symmetric or late asymmetric growth abnormality patterns depending on the fetal stage of development, of which the latter is most common occurring in 70–80% of growth-restricted infants. Deformation is the consequence of extrinsic biomechanical factors interfering with normal growth, functioning, or positioning of the fetus in utero, typically arising during late gestation. Biomechanical forces play a critical role in the normal morphogenesis of most tissues. The magnitude and direction of force impact the form of the developing fetus, with a specific tissue response depending on its pliability and stage of development. Major uterine constraining factors include primigravida, small maternal size, uterine malformation, uterine fibromata, early pelvic engagement of the fetal head, aberrant fetal position, oligohydramnios, and multifetal gestation. Corrective mechanical forces similar to those that gave rise to the deformation to reshape the deformed structures are often used and should take advantage of the rapid postnatal growth to correct form. PMID:22888434

  18. Factors influencing phenolic compounds in table olives (Olea europaea).

    PubMed

    Charoenprasert, Suthawan; Mitchell, Alyson

    2012-07-25

    The Mediterranean diet appears to be associated with a reduced risk of several chronic diseases including cancer and cardiovascular and Alzheimer's diseases. Olive products (mainly olive oil and table olives) are important components of the Mediterranean diet. Olives contain a range of phenolic compounds; these natural antioxidants may contribute to the prevention of these chronic conditions. Consequently, the consumption of table olives and olive oil continues to increase worldwide by health-conscious consumers. There are numerous factors that can affect the phenolics in table olives including the cultivar, degree of ripening, and, importantly, the methods used for curing and processing table olives. The predominant phenolic compound found in fresh olive is the bitter secoiridoid oleuropein. Table olive processing decreases levels of oleuropein with concomitant increases in the hydrolysis products hydroxytyrosol and tyrosol. Many of the health benefits reported for olives are thought to be associated with the levels of hydroxytyrosol. Herein the pre- and post-harvest factors influencing the phenolics in olives, debittering methods, and health benefits of phenolics in table olives are reviewed. PMID:22720792

  19. FACTORS INFLUENCING MISTIMED AND UNWANTED PREGNANCIES AMONG NEPALI WOMEN.

    PubMed

    Acharya, Pawan; Gautam, Rupesh; Aro, Arja R

    2016-03-01

    This paper assesses the factors influencing mistimed and unwanted pregnancies in Nepal separately using data from the 2011 Nepal Demographic and Health Survey. Women who had given birth within the five years before the survey were interviewed about the intendedness of their last pregnancy. The data were analysed with a chi-squared test, followed by multiple logistic regression analysis. Among the total 5391 participants, 11.29% and 13.13% reported their last pregnancy as mistimed and unwanted respectively. Logistic regression analysis showed that women from the hill region were more likely to report mistimed pregnancy, while women from the Western and Far-Western development regions were less likely to report mistimed pregnancy. Education status was positively correlated with the reporting of mistimed pregnancy. Women involved in agriculture, with full autonomy on household decision, with some exposure to mass media, belonging to higher age group and having third or higher parity were less likely to report mistimed pregnancy. Similarly, women from the Western development region had relatively higher odds of reporting unwanted pregnancy. Women with husbands involved in a paid job had lower odds of unwanted pregnancy. Women's autonomy was also positively correlated with unwanted pregnancy. Women with the intention to use contraceptive had lower odds of unwanted pregnancy. Interventions targeting the factors identified by this study could be useful in reduction of mistimed and unwanted pregnancies among Nepali women. PMID:26008148

  20. Abiotic factors influence plant storage lipid accumulation and composition.

    PubMed

    Singer, Stacy D; Zou, Jitao; Weselake, Randall J

    2016-02-01

    The demand for plant-derived oils has increased substantially over the last decade, and is sure to keep growing. While there has been a surge in research efforts to produce plants with improved oil content and quality, in most cases the enhancements have been small. To add further complexity to this situation, substantial differences in seed oil traits among years and field locations have indicated that plant lipid biosynthesis is also influenced to a large extent by multiple environmental factors such as temperature, drought, light availability and soil nutrients. On the molecular and biochemical levels, the expression and/or activities of fatty acid desaturases, as well as diacylglycerol acyltransferase 1, have been found to be affected by abiotic factors, suggesting that they play a role in the lipid content and compositional changes seen under abiotic stress conditions. Unfortunately, while only a very small number of strategies have been developed as of yet to minimize these environmental effects on the production of storage lipids, it is clear that this feat will be of the utmost importance for developing superior oil crops with the capability to perform in a consistent manner in field conditions in the future. PMID:26795146