Molecular Linkage Mapping and Marker-Trait Associations with NlRPT, a Downy Mildew Resistance Gene in Nicotiana langsdorffii

PubMed Central

Zhang, Shouan; Gao, Muqiang; Zaitlin, David

2012-01-01

Nicotiana langsdorffii is one of two species of Nicotiana known to express an incompatible interaction with the oomycete Peronospora tabacina, the causal agent of tobacco blue mold disease. We previously showed that incompatibility is due to the hypersensitive response (HR), and plants expressing the HR are resistant to P. tabacina at all stages of growth. Resistance is due to a single dominant gene in N. langsdorffii accession S-4-4 that we have named NlRPT. In further characterizing this unique host-pathogen interaction, NlRPT has been placed on a preliminary genetic map of the N. langsdorffii genome. Allelic scores for five classes of DNA markers were determined for 90 progeny of a “modified backcross” involving two N. langsdorffii inbred lines and the related species N. forgetiana. All markers had an expected segregation ratio of 1:1, and were scored in a common format. The map was constructed with JoinMap 3.0, and loci showing excessive transmission distortion were removed. The linkage map consists of 266 molecular marker loci defined by 217 amplified fragment length polymorphisms (AFLPs), 26 simple-sequence repeats (SSRs), 10 conserved orthologous sequence markers, nine inter-simple sequence repeat markers, and four target region amplification polymorphism markers arranged in 12 linkage groups with a combined length of 1062 cM. NlRPT is located on linkage group three, flanked by four AFLP markers and one SSR. Regions of skewed segregation were detected on LGs 1, 5, and 9. Markers developed for N. langsdorffii are potentially useful genetic tools for other species in Nicotiana section Alatae, as well as in N. benthamiana. We also investigated whether AFLPs could be used to infer genetic relationships within N. langsdorffii and related species from section Alatae. A phenetic analysis of the AFLP data showed that there are two main lineages within N. langsdorffii, and that both contain populations expressing dominant resistance to P. tabacina. PMID

14 CFR 330.29 - What information must air taxi operators submit on Form 330 (Final) and Form 330-C?

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false What information must air taxi operators... COMPENSATION OF AIR CARRIERS Application Procedures § 330.29 What information must air taxi operators submit on Form 330 (Final) and Form 330-C? As an air taxi operator, you must complete Form 330 (Final) in...

14 CFR 330.29 - What information must air taxi operators submit on Form 330 (Final) and Form 330-C?

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false What information must air taxi operators... COMPENSATION OF AIR CARRIERS Application Procedures § 330.29 What information must air taxi operators submit on Form 330 (Final) and Form 330-C? As an air taxi operator, you must complete Form 330 (Final) in...

Reduction of RPT6/S8 (a Proteasome Component) and Proteasome Activity in the Cortex is Associated with Cognitive Impairment in Lewy Body Dementia

PubMed Central

Alghamdi, Amani; Vallortigara, Julie; Howlett, David R.; Broadstock, Martin; Hortobágyi, Tibor; Ballard, Clive; Thomas, Alan J.; O’Brien, John T.; Aarsland, Dag; Attems, Johannes; Francis, Paul T.; Whitfield, David R.

2017-01-01

Lewy body dementia is the second most common neurodegenerative dementia and is pathologically characterized by α-synuclein positive cytoplasmic inclusions, with varying amounts of amyloid-β (Aβ) and hyperphosphorylated tau (tau) aggregates in addition to synaptic loss. A dysfunctional ubiquitin proteasome system (UPS), the major proteolytic pathway responsible for the clearance of short lived proteins, may be a mediating factor of disease progression and of the development of α-synuclein aggregates. In the present study, protein expression of a key component of the UPS, the RPT6 subunit of the 19S regulatory complex was determined. Furthermore, the main proteolytic-like (chymotrypsin- and PGPH-) activities have also been analyzed. The middle frontal (Brodmann, BA9), inferior parietal (BA40), and anterior cingulate (BA24) gyrus’ cortex were selected as regions of interest from Parkinson’s disease dementia (PDD, n = 31), dementia with Lewy bodies (DLB, n = 44), Alzheimer’s disease (AD, n = 16), and control (n = 24) brains. Clinical and pathological data available included the MMSE score. DLB, PDD, and AD were characterized by significant reductions of RPT6 (one-way ANOVA, p < 0.001; Bonferroni post hoc test) in prefrontal cortex and parietal cortex compared with controls. Strong associations were observed between RPT6 levels in prefrontal, parietal cortex, and anterior cingulate gyrus and cognitive impairment (p = 0.001, p = 0.001, and p = 0.008, respectively). These findings highlight the involvement of the UPS in Lewy body dementia and indicate that targeting the UPS may have the potential to slow down or reduce the progression of cognitive impairment in DLB and PDD. PMID:28269775

A single effector protein, ArvRpt2ea from Erwinia amylovora, can cause fire blight disease symptons and induces salicylic acid dependent defense response

USDA-ARS?s Scientific Manuscript database

The AvrRpt2EA effector protein of Erwinia amylovora is important for pathogen recognition in the fire blight resistant crabapple Malus ×robusta 5; however, little is known about its role in susceptible apple genotypes. In order to study its function in planta, we expressed a plant optimized version...

Evaluation of Forces on the Welding Probe of the Automated Retractable Pin-Tool (RPT)

NASA Technical Reports Server (NTRS)

Ding, R. J.

2001-01-01

The NASA invention entitled 'The Hydraulic Controlled Auto-Adjustable Pin Tool for Friction Stir Welding' (US Patent 5,893,507), better known as the Retractable Pin-Tool (RPT), has been instrumented with a load-detecting device allowing the forces placed on the welding probe to be measured. As the welding probe is plunged into the material, the forces placed on the probe can now be characterized. Of particular interest are those forces experienced as the welding probe comes within close proximity to the back-up anvil. For a given material, it is believed that unique forces are generated relative to the distance between the welding probe and the anvil. The forces have been measured and characterized for several materials, and correlations have been made between these forces and the pin's position relative to the backside of the weld material.

Tooele Army Depot Revised Final Site-Wide Ecological Risk Assessment. Volume II (Appendices A through D).

DTIC Science & Technology

1998-02-01

diet of higher trophic level species, such as raptors. Ord’s Kangaroo Rat (Dipodomys ordii). The Ord’s kangaroo rat is chiefly a nocturnal mammal...sandy soils. The entrances of these burrow systems are plugged during the day to maintain humidity and coolness. The kangaroo rat can obtain...sufficient quantities of water from the metabolism of food in their diet, but will drink water when it is available. TSK 0003/SWERA/Rev Final Rpt/November

Final Technical Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Glasser, Alan H.

Final technical report on DE-SC0016106. This is the final technical report for a portion of the multi-institutional CEMM project. This report is centered around 3 publications and a seminar presentation, which have been submitted to E-Link.

Final Report of Tank 241-C-105 Dissolution, the Phase 2 Study

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meznarich, Huei K.; bolling, Stacey D.; Cooke, Gary A.

2016-10-01

Three clamshell grab samples were taken from Tank 241-C-105 in October 2015 in accordance with RPP-PLAN-60011. Analytical results of those samples were issued in the report RPP-RPT-59115 by Wastren Advantage, Inc., Hanford Laboratory. Solid phase characterization results were reported separately in LAB-RPT-15-00011 and in RPP-RPT-59147. The major solid phases reported to be present were dawsonite [NaAlCO 3(OH) 2], trona [Na 3(HCO 3)(CO 3)·2H 2O], cejkaite [Na 4(UO 2)(CO 3) 3], and an unidentified organic solid, with minor amounts of gibbsite [Al(OH) 3], natrophosphate [Na 7F(PO 4) 2·19H 2O], and traces of unidentified iron-rich and manganese-rich phases. Note that the presencemore » of dawsonite, trona, and cejkaite requires a relatively low pH, likely around pH 9 to 10. One aliquot of each grab sample was provided to 222-S Laboratory Process Chemistry for dissolution studies. Phase 1 of the dissolution testing followed the approved test plan, WRPS-1404813, Rev. 3, and examined the behavior of the Tank 241-C-105 solids treated with water, 19M sodium hydroxide, 2M nitric acid, and 0.5M oxalic acid/2M nitric acid. Phase 2 of the testing was conducted in accordance with instructions from the client and emphasized treatment with 19M sodium hydroxide followed by water washing. This is the report of the Phase 2 testing.« less

48 CFR 1552.211-77 - Final reports.

Code of Federal Regulations, 2013 CFR

2013-10-01

... reports. As prescribed in 1511.011-77, insert this contract clause when a contract requires both a draft and a final report. FINAL REPORTS (SEP 2013) (a) “Draft Report”__The Contractor shall submit to the Contracting Officer's Representative __ copies of the draft final report on or before ___ (date) __ The...

MATS E-Reporting Final Action

EPA Pesticide Factsheets

This page describes the interim final rule that will allow owners or operators of electric generating units to submit to EPA electronic emissions and compliance reports for the Mercury and Air Toxics rule.

2008 Ozone National Ambient Air Quality Standards (NAAQS) Findings of Failure to Submit

EPA Pesticide Factsheets

This final action finds that 15 states and the District of Columbia have failed to submit specific state implementation plan (SIP) elements to satisfy certain nonattainment area, and/or Ozone Transport Region (OTR), planning requirements for the 2008 ozone

34 CFR 668.137 - Deadlines for submitting documentation and the consequences of failure to submit documentation.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 3 2010-07-01 2010-07-01 false Deadlines for submitting documentation and the consequences of failure to submit documentation. 668.137 Section 668.137 Education Regulations of the Offices... documentation and the consequences of failure to submit documentation. (a) A student shall submit before a...

21 CFR 1271.21 - When do I register, submit an HCT/P list, and submit updates?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 8 2011-04-01 2011-04-01 false When do I register, submit an HCT/P list, and... Listing § 1271.21 When do I register, submit an HCT/P list, and submit updates? (a) You must register and submit a list of every HCT/P that your establishment manufactures within 5 days after beginning...

21 CFR 1271.21 - When do I register, submit an HCT/P list, and submit updates?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false When do I register, submit an HCT/P list, and... Listing § 1271.21 When do I register, submit an HCT/P list, and submit updates? (a) You must register and submit a list of every HCT/P that your establishment manufactures within 5 days after beginning...

21 CFR 1271.21 - When do I register, submit an HCT/P list, and submit updates?

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 8 2012-04-01 2012-04-01 false When do I register, submit an HCT/P list, and... Listing § 1271.21 When do I register, submit an HCT/P list, and submit updates? (a) You must register and submit a list of every HCT/P that your establishment manufactures within 5 days after beginning...

21 CFR 822.14 - May I reference information previously submitted instead of submitting it again?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false May I reference information previously submitted..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES POSTMARKET SURVEILLANCE Postmarket Surveillance Plan § 822.14 May I reference information previously submitted instead of submitting it again? Yes...

Reconfiguration of the proteasome during chaperone-mediated assembly

PubMed Central

Park, Soyeon; Li, Xueming; Kim, Ho Min; Singh, Chingakham Ranjit; Tian, Geng; Hoyt, Martin A.; Lovell, Scott; Battaile, Kevin P.; Zolkiewski, Michal; Coffino, Philip; Roelofs, Jeroen; Cheng, Yifan; Finley, Daniel

2013-01-01

The proteasomal ATPase ring, comprising Rpt1-Rpt6, associates with the heptameric α ring of the proteasome core particle (CP) in the mature proteasome, with the Rpt C-terminal tails inserting into pockets of the α ring1–4. Rpt ring assembly is mediated by four chaperones, each binding a distinct Rpt subunit5–10. We report that the base subassembly of the proteasome, which includes the Rpt ring, forms a high affinity complex with the CP. This complex is subject to active dissociation by the chaperones Hsm3, Nas6, and Rpn14. Chaperone-mediated dissociation was abrogated by a nonhydrolyzable ATP analog, indicating that chaperone action is coupled to nucleotide hydrolysis by the Rpt ring. Unexpectedly, synthetic Rpt tail peptides bound α pockets with poor specificity, except for Rpt6, which uniquely bound the α2/α3 pocket. Although the Rpt6 tail is not visualized within an α pocket in mature proteasomes2–4, it inserts into the α2/α3 pocket in the base-CP complex and is important for complex formation. Thus, the Rpt-CP interface is reconfigured when the lid complex joins the nascent proteasome to form the mature holoenzyme. PMID:23644457

75 FR 45145 - Notice of Submission of Proposed Information Collection to OMB Final Endorsement of Credit...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-02

... requirement described below has been submitted to the Office of Management and Budget (OMB) for review, as... mortgagee/lender submits information to indicate the schedule of advances made on the project and the final advance to be disbursed immediately upon final endorsement. DATES: Comments Due Date: September 1, 2010...

Improving gross anatomy learning using reciprocal peer teaching.

PubMed

Manyama, Mange; Stafford, Renae; Mazyala, Erick; Lukanima, Anthony; Magele, Ndulu; Kidenya, Benson R; Kimwaga, Emmanuel; Msuya, Sifael; Kauki, Julius

2016-03-22

The use of cadavers in human anatomy teaching requires adequate number of anatomy instructors who can provide close supervision of the students. Most medical schools are facing challenges of lack of trained individuals to teach anatomy. Innovative techniques are therefore needed to impart adequate and relevant anatomical knowledge and skills. This study was conducted in order to evaluate the traditional teaching method and reciprocal peer teaching (RPT) method during anatomy dissection. Debriefing surveys were administered to the 227 first year medical students regarding merits, demerits and impact of both RPT and Traditional teaching experiences on student's preparedness prior to dissection, professionalism and communication skills. Out of this, 159 (70 %) completed the survey on traditional method while 148 (65.2 %) completed survey on RPT method. An observation tool for anatomy faculty was used to assess collaboration, professionalism and teaching skills among students. Student's scores on examinations done before introduction of RPT were compared with examinations scores after introduction of RPT. Our results show that the mean performance of students on objective examinations was significantly higher after introduction of RPT compared to the performance before introduction of RPT [63.7 ± 11.4 versus 58.6 ± 10, mean difference 5.1; 95 % CI = 4.0-6.3; p-value < 0.0001]. Students with low performance prior to RPT benefited more in terms of examination performance compared to those who had higher performance [Mean difference 7.6; p-value < 0.0001]. Regarding student's opinions on traditional method versus RPT, 83 % of students either agreed or strongly agreed that they were more likely to read the dissection manual before the RPT dissection session compared to 35 % for the traditional method. Over 85 % of respondents reported that RPT improved their confidence and ability to present information to peers and faculty compared to 38 % for

Disruption of ROOT PHOTOTROPISM2 gene does not affect phototropin-mediated stomatal opening.

PubMed

Tsutsumi, Toshifumi; Takemiya, Atsushi; Harada, Akiko; Shimazaki, Ken-ichiro

2013-03-01

Phototropins (phot1 and phot2), blue light-receptor protein kinases in plants, mediate stomatal opening by activating the plasma membrane H(+)-ATPase in guard cells, but the signaling from phototropins to the H(+)-ATPase remains unknown. A recent study concluded that ROOT PHOTOTROPISM2 (RPT2) is involved in the primary step of this process. However, this conclusion is based solely on the determination of stomatal apertures in the epidermis. We investigated the role of RPT2 in blue light-dependent stomatal opening in more detail. We generated double mutants of rpt2 and phototropins (phot1 or phot2) in the Col ecotype background and obtained the typical phenotypes of rpt2 mutants, including the impairment in phototropism. In contrast, neither blue light-dependent H(+) pumping nor blue light-dependent H(+)-ATPase activation in guard cells was affected in the rpt2 mutants of rpt2, phot1 rpt2, and phot2 rpt2. Stomata in these rpt2 mutants opened widely by blue light in both epidermal peels and intact leaves, and no difference in the responses was found between the wild type and the mutants. From these results, we concluded that RPT2 gene disruption does not affect blue light-dependent stomatal opening. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

The Amherst Project. Final Report.

ERIC Educational Resources Information Center

Hampshire Coll., Amherst, MA.

This final report submitted by the Committee on the Study of History at Hampshire College describes the Amherst Project, a research and development project devoted to fostering the newer inquiry approaches in the study of United States history. The project's main focus has been on secondary schools, but has also encompassed junior high and adult…

32 CFR 989.20 - Final EIS.

Code of Federal Regulations, 2010 CFR

2010-07-01

... limited to factual corrections and responses to comments, the proponent and EPF may, with the prior..., the EPF must submit the Draft EIS and all of the above documents, with a new cover sheet indicating... more extensive modifications are required, the EPF must prepare a preliminary final EIS incorporating...

29 CFR 1952.313 - Final approval determination.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 1902. Accordingly, the Hawaii plan was granted final approval and concurrent Federal enforcement... employment in Hawaii. The plan does not cover maritime employment in the private sector; Federal government... effective as operations under the Federal program; to submit plan supplements in accordance with 29 CFR part...

29 CFR 1952.294 - Final approval determination.

Code of Federal Regulations, 2013 CFR

2013-07-01

.... Accordingly, the Nevada plan was granted final approval and concurrent Federal enforcement authority was... Nevada. The plan does not cover Federal government employers and employees; any private sector maritime... under the Federal program; to submit plan supplements in accordance with 29 CFR Part 1953; to allocate...

29 CFR 1952.294 - Final approval determination.

Code of Federal Regulations, 2010 CFR

2010-07-01

.... Accordingly, the Nevada plan was granted final approval and concurrent Federal enforcement authority was... Nevada. The plan does not cover Federal government employers and employees; any private sector maritime... under the Federal program; to submit plan supplements in accordance with 29 CFR Part 1953; to allocate...

Pueraria thunbergiana inhibits cisplatin-induced damage of HEI-OC1 auditory cells through scavenging free radicals.

PubMed

Yu, Hyeon-Hee; Jung, Su-Young; Shin, Mee-Kyung; Park, Raekil; So, Hong-Seob; You, Yong-Ouk

2010-06-01

The radix of Pueraria thunbergiana (P. thunbergiana) is traditionally prescribed to attenuate the clinical manifestation of inner ear dysfunction and various clinical situations including fevers, gastrointestinal disorders, skin problems, migraine headaches, lowering cholesterol, and treating chronic alcoholism in oriental medicine. In the present study, we examined the protective effect of ethanol extract of the radix of P. thunbergiana (RPT) on cisplatin-induced damage of HEI-OC1 auditory hair cells. When the cells were cultured in the medium containing 5-100 microg/mL of RPT, RPT showed protective effect against the cisplatin-induced HEI-OC1 cell damage. We also measured the effects of RPT on lipid peroxidation of cisplatin-treated cells as well as scavenging activities against superoxide radical, hydroxyl radical, hydrogen peroxide, and DPPH radical. RPT reduced cisplatin-induced lipid peroxidation in a dose-dependent manner. Furthermore, RPT showed strong scavenging activity against superoxide radical, hydroxyl radical, hydrogen peroxide, and DPPH radical. These results indicate that RPT protects cisplatin-induced HEI-OC1 cell damage through inhibition of lipid peroxidation and scavenging activities of free radials. (c) 2009 John Wiley & Sons, Ltd.

77 FR 69788 - Colorado: Final Authorization of State Hazardous Waste Management Program Revisions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-21

...: Final Authorization of State Hazardous Waste Management Program Revisions AGENCY: Environmental... authorization of changes to its hazardous waste program under the Resource Conservation and Recovery Act (RCRA). The EPA proposes to grant final authorization to the hazardous waste program changes submitted by the...

Conventional physical therapy and physical therapy based on reflex stimulation showed similar results in children with myelomeningocele.

PubMed

Aizawa, Carolina Y P; Morales, Mariana P; Lundberg, Carolina; Moura, Maria Clara D Soares de; Pinto, Fernando C G; Voos, Mariana C; Hasue, Renata H

2017-03-01

We aimed to investigate whether infants with myelomeningocele would improve their motor ability and functional independence after ten sessions of physical therapy and compare the outcomes of conventional physical therapy (CPT) to a physical therapy program based on reflex stimulation (RPT). Twelve children were allocated to CPT (n = 6, age 18.3 months) or RPT (n = 6, age 18.2 months). The RPT involved proprioceptive neuromuscular facilitation. Children were assessed with the Gross Motor Function Measure and the Pediatric Evaluation of Disability Inventory before and after treatment. Mann-Whitney tests compared the improvement on the two scales of CPT versus RPT and the Wilcoxon test compared CPT to RPT (before vs. after treatment). Possible correlations between the two scales were tested with Spearman correlation coefficients. Both groups showed improvement on self-care and mobility domains of both scales. There were no differences between the groups, before, or after intervention. The CPT and RPT showed similar results after ten weeks of treatment.

Resonant photon tunneling via surface plasmon polaritons through one-dimensional metal-dielectric metamaterials.

PubMed

Tomita, Satoshi; Yokoyama, Takashi; Yanagi, Hisao; Wood, Ben; Pendry, John B; Fujii, Minoru; Hayashi, Shinji

2008-06-23

We report resonant photon tunneling (RPT) through one-dimensional metamaterials consisting of alternating layers of metal and dielectric. RPT via a surface plasmon polariton state permits evanescent light waves with large wavenumbers to be conveyed through the metamaterial. This is the mechanism for sub-wavelength imaging recently demonstrated with a super-lens. Furthermore, we find that the RPT peak is shifted from the reflectance dip with increasing the number of Al layers, indicating that the shift is caused by the losses in the RPT.

EXPANDING INFANT MENTAL HEALTH TREATMENT SERVICES TO AT-RISK PRESCHOOLERS AND THEIR FAMILIES THROUGH THE INTEGRATION OF RELATIONAL PLAY THERAPY.

PubMed

Farley, Jennifer L; Whipple, Ellen E

2017-09-01

The expansion of infant mental health (IMH) to at-risk preschoolers and their families has contributed to the integration of relational play therapy (RPT) into IMH treatment services for this population. Integrating RPT allows access to specialized play and expressive techniques specific to preschool and family development, which improves the clinical ability to meet the multiple and complex needs of at-risk parent-child dyads and their families. This article will examine the RPT literature and explore the similarities and differences between IMH and RPT. In addition, two case studies will highlight a five-phase, integrative clinical-treatment process and provide insight into how IMH clinicians are integrating RPT models and maintaining adherence to the IMH treatment approach. © 2017 Michigan Association for Infant Mental Health.

Examining Evolutions in the Adoption of Metacognitive Regulation in Reciprocal Peer Tutoring Groups

ERIC Educational Resources Information Center

De Backer, Liesje; Van Keer, Hilde; Moerkerke, Beatrijs; Valcke, Martin

2016-01-01

We aimed to investigate how metacognitive regulation is characterised during collaborative learning in a higher education reciprocal peer tutoring (RPT) setting. Sixty-four Educational Sciences students participated in a semester-long RPT-intervention and tutored one another in small groups of six. All sessions of five randomly selected RPT-groups…

7 CFR 1493.250 - Final application and issuance of a facility payment guarantee.

Code of Federal Regulations, 2014 CFR

2014-01-01

...) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE EXPORT PROGRAMS CCC EXPORT CREDIT GUARANTEE PROGRAMS CCC Facility Guarantee Program (FGP) Operations § 1493.250 Final application and issuance of a... commitment may, within six months of the date of such letter, submit a final application to CCC for a...

7 CFR 1493.250 - Final application and issuance of a facility payment guarantee.

Code of Federal Regulations, 2013 CFR

2013-01-01

...) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE EXPORT PROGRAMS CCC EXPORT CREDIT GUARANTEE PROGRAMS CCC Facility Guarantee Program (FGP) Operations § 1493.250 Final application and issuance of a... commitment may, within six months of the date of such letter, submit a final application to CCC for a...

7 CFR 1493.250 - Final application and issuance of a facility payment guarantee.

Code of Federal Regulations, 2012 CFR

2012-01-01

...) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE EXPORT PROGRAMS CCC EXPORT CREDIT GUARANTEE PROGRAMS CCC Facility Guarantee Program (FGP) Operations § 1493.250 Final application and issuance of a... commitment may, within six months of the date of such letter, submit a final application to CCC for a...

PrimateLit Database: Submit Literature for Indexing

Science.gov Websites

Access PrimateLit Using this Site About the Project Submit Literature for Indexing Copyright Info Center WI Regional Primate Resource Center Submit Literature for Indexing PrimateLit has not been

A β-solenoid model of the Pmel17 repeat domain: insights to the formation of functional amyloid fibrils

NASA Astrophysics Data System (ADS)

Louros, Nikolaos N.; Baltoumas, Fotis A.; Hamodrakas, Stavros J.; Iconomidou, Vassiliki A.

2016-02-01

Pmel17 is a multidomain protein involved in biosynthesis of melanin. This process is facilitated by the formation of Pmel17 amyloid fibrils that serve as a scaffold, important for pigment deposition in melanosomes. A specific luminal domain of human Pmel17, containing 10 tandem imperfect repeats, designated as repeat domain (RPT), forms amyloid fibrils in a pH-controlled mechanism in vitro and has been proposed to be essential for the formation of the fibrillar matrix. Currently, no three-dimensional structure has been resolved for the RPT domain of Pmel17. Here, we examine the structure of the RPT domain by performing sequence threading. The resulting model was subjected to energy minimization and validated through extensive molecular dynamics simulations. Structural analysis indicated that the RPT model exhibits several distinct properties of β-solenoid structures, which have been proposed to be polymerizing components of amyloid fibrils. The derived model is stabilized by an extensive network of hydrogen bonds generated by stacking of highly conserved polar residues of the RPT domain. Furthermore, the key role of invariant glutamate residues is proposed, supporting a pH-dependent mechanism for RPT domain assembly. Conclusively, our work attempts to provide structural insights into the RPT domain structure and to elucidate its contribution to Pmel17 amyloid fibril formation.

Computational modeling of Repeat1 region of INI1/hSNF5: An evolutionary link with ubiquitin

PubMed Central

Bhutoria, Savita

2016-01-01

Abstract The structure of a protein can be very informative of its function. However, determining protein structures experimentally can often be very challenging. Computational methods have been used successfully in modeling structures with sufficient accuracy. Here we have used computational tools to predict the structure of an evolutionarily conserved and functionally significant domain of Integrase interactor (INI)1/hSNF5 protein. INI1 is a component of the chromatin remodeling SWI/SNF complex, a tumor suppressor and is involved in many protein‐protein interactions. It belongs to SNF5 family of proteins that contain two conserved repeat (Rpt) domains. Rpt1 domain of INI1 binds to HIV‐1 Integrase, and acts as a dominant negative mutant to inhibit viral replication. Rpt1 domain also interacts with oncogene c‐MYC and modulates its transcriptional activity. We carried out an ab initio modeling of a segment of INI1 protein containing the Rpt1 domain. The structural model suggested the presence of a compact and well defined ββαα topology as core structure in the Rpt1 domain of INI1. This topology in Rpt1 was similar to PFU domain of Phospholipase A2 Activating Protein, PLAA. Interestingly, PFU domain shares similarity with Ubiquitin and has ubiquitin binding activity. Because of the structural similarity between Rpt1 domain of INI1 and PFU domain of PLAA, we propose that Rpt1 domain of INI1 may participate in ubiquitin recognition or binding with ubiquitin or ubiquitin related proteins. This modeling study may shed light on the mode of interactions of Rpt1 domain of INI1 and is likely to facilitate future functional studies of INI1. PMID:27261671

Computational modeling of Repeat1 region of INI1/hSNF5: An evolutionary link with ubiquitin.

PubMed

Bhutoria, Savita; Kalpana, Ganjam V; Acharya, Seetharama A

2016-09-01

The structure of a protein can be very informative of its function. However, determining protein structures experimentally can often be very challenging. Computational methods have been used successfully in modeling structures with sufficient accuracy. Here we have used computational tools to predict the structure of an evolutionarily conserved and functionally significant domain of Integrase interactor (INI)1/hSNF5 protein. INI1 is a component of the chromatin remodeling SWI/SNF complex, a tumor suppressor and is involved in many protein-protein interactions. It belongs to SNF5 family of proteins that contain two conserved repeat (Rpt) domains. Rpt1 domain of INI1 binds to HIV-1 Integrase, and acts as a dominant negative mutant to inhibit viral replication. Rpt1 domain also interacts with oncogene c-MYC and modulates its transcriptional activity. We carried out an ab initio modeling of a segment of INI1 protein containing the Rpt1 domain. The structural model suggested the presence of a compact and well defined ββαα topology as core structure in the Rpt1 domain of INI1. This topology in Rpt1 was similar to PFU domain of Phospholipase A2 Activating Protein, PLAA. Interestingly, PFU domain shares similarity with Ubiquitin and has ubiquitin binding activity. Because of the structural similarity between Rpt1 domain of INI1 and PFU domain of PLAA, we propose that Rpt1 domain of INI1 may participate in ubiquitin recognition or binding with ubiquitin or ubiquitin related proteins. This modeling study may shed light on the mode of interactions of Rpt1 domain of INI1 and is likely to facilitate future functional studies of INI1. © 2016 The Protein Society.

Potato NPH3/RPT2-Like Protein StNRL1, Targeted by a Phytophthora infestans RXLR Effector, Is a Susceptibility Factor.

PubMed

Yang, Lina; McLellan, Hazel; Naqvi, Shaista; He, Qin; Boevink, Petra C; Armstrong, Miles; Giuliani, Licida M; Zhang, Wei; Tian, Zhendong; Zhan, Jiasui; Gilroy, Eleanor M; Birch, Paul R J

2016-05-01

Plant pathogens deliver effectors to manipulate host processes. We know little about how fungal and oomycete effectors target host proteins to promote susceptibility, yet such knowledge is vital to understand crop disease. We show that either transient expression in Nicotiana benthamiana, or stable transgenic expression in potato (Solanum tuberosum), of the Phytophthora infestans RXLR effector Pi02860 enhances leaf colonization by the pathogen. Expression of Pi02860 also attenuates cell death triggered by the P. infestans microbe-associated molecular pattern INF1, indicating that the effector suppresses pattern-triggered immunity. However, the effector does not attenuate cell death triggered by Cf4/Avr4 coexpression, showing that it does not suppress all cell death activated by cell surface receptors. Pi02860 interacts in yeast two-hybrid assays with potato NPH3/RPT2-LIKE1 (NRL1), a predicted CULLIN3-associated ubiquitin E3 ligase. Interaction of Pi02860 in planta was confirmed by coimmunoprecipitation and bimolecular fluorescence complementation assays. Virus-induced gene silencing of NRL1 in N. benthamiana resulted in reduced P. infestans colonization and accelerated INF1-mediated cell death, indicating that this host protein acts as a negative regulator of immunity. Moreover, whereas NRL1 virus-induced gene silencing had no effect on the ability of the P. infestans effector Avr3a to suppress INF1-mediated cell death, such suppression by Pi02860 was significantly attenuated, indicating that this activity of Pi02860 is mediated by NRL1. Transient overexpression of NRL1 resulted in the suppression of INF1-mediated cell death and enhanced P. infestans leaf colonization, demonstrating that NRL1 acts as a susceptibility factor to promote late blight disease. © 2016 American Society of Plant Biologists. All Rights Reserved.

How to Submit a Risk Management Plan (RMP) to EPA

EPA Pesticide Factsheets

RMP*eSubmit software is the only way to submit RMPs. After you have prepared your plan using RMP*eSubmit, you may also re-submit, correct, or withdraw an RMP. Another electronic tool, RMP*Comp, performs the required off-site consequence analysis.

Medicaid program; correction and reduction plans for intermediate care facilities for the mentally retarded--HCFA. Final rule.

PubMed

1991-07-05

This final rule amends the portions of the Medicaid regulations under which an intermediate care facility for the mentally retarded (ICF/MR) with substantial deficiencies that did not pose an immediate jeopardy to the health and safety of clients could continue participation in the Medicaid program. These regulations gave State Medicaid agencies the option of submitting written plans to either correct deficiencies or permanently reduce the number of beds in the certified portion of the facility. This rule removes all requirements for submitting, approving, and monitoring correction plans for ICFs/MR. The requirements for submitting and approving correction plans are being removed because the time limit for submission of these plans has passed. The provisions for monitoring correction plans are being removed because there are no remaining facilities for which these provisions apply. This final rule also removes requirements for submitting and approving reduction plans for ICFs/MR because the time limit for submitting these plans has passed. It retains and updates the requirements for monitoring and compliance that apply to those ICFs/MR for which reduction plans were approved by January 1, 1990.

Trehalose protects against cadmium-induced cytotoxicity in primary rat proximal tubular cells via inhibiting apoptosis and restoring autophagic flux

PubMed Central

Wang, Xin-Yu; Yang, Heng; Wang, Min-Ge; Yang, Du-Bao; Wang, Zhen-Yong; Wang, Lin

2017-01-01

Autophagy has an important renoprotective function and we recently found that autophagy inhibition is involved in cadmium (Cd)-induced nephrotoxicity. Here, we aimed to investigate the protective effect of trehalose (Tre), a novel autophagy activator, against Cd-induced cytotoxicity in primary rat proximal tubular (rPT) cells. First, data showed that Tre treatment significantly decreased Cd-induced apoptotic cell death of rPT cells via inhibiting caspase-dependent apoptotic pathway, evidenced by morphological analysis, flow cytometric and immunoblot assays. Also, administration with Tre protected rPT cells against Cd-induced lipid peroxidation. Inhibition of autophagic flux in Cd-exposed rPT cells was markedly restored by Tre administration, demonstrated by immunoblot analysis of autophagy marker proteins and GFP and RFP tandemly tagged LC3 method. Resultantly, Cd-induced autophagosome accumulation was obviously alleviated by Tre treatment. Meanwhile, blockage of autophagosome–lysosome fusion by Cd exposure was noticeably restored by Tre, which promoted the autophagic degradation in Cd-exposed rPT cells. Moreover, Tre treatment markedly recovered Cd-induced lysosomal alkalinization and impairment of lysosomal degradation capacity in rPT cells, demonstrating that Tre has the ability to restore Cd-impaired lysosomal function. Collectively, these findings demonstrate that Tre treatment alleviates Cd-induced cytotoxicity in rPT cells by inhibiting apoptosis and restoring autophagic flux. PMID:29022917

18 CFR 154.302 - Previously submitted material.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Previously submitted material. 154.302 Section 154.302 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... Filed With Changes § 154.302 Previously submitted material. (a) If all, or any portion, of the...

18 CFR 154.302 - Previously submitted material.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Previously submitted material. 154.302 Section 154.302 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... Filed With Changes § 154.302 Previously submitted material. (a) If all, or any portion, of the...

18 CFR 154.302 - Previously submitted material.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Previously submitted material. 154.302 Section 154.302 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... Filed With Changes § 154.302 Previously submitted material. (a) If all, or any portion, of the...

18 CFR 154.302 - Previously submitted material.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Previously submitted material. 154.302 Section 154.302 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... Filed With Changes § 154.302 Previously submitted material. (a) If all, or any portion, of the...

32 CFR Appendix C to Part 282 - Submitting a Claim

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 2 2010-07-01 2010-07-01 false Submitting a Claim C Appendix C to Part 282.... 282, App. C Appendix C to Part 282—Submitting a Claim (a) Who May Submit a Claim. Any person (“claimant”) may submit a claim who has a demand for money or property against the Government under 31 U.S.C...

In vitro studies with renal proximal tubule cells show direct cytotoxicity of Androctonus australis hector scorpion venom triggered by oxidative stress, caspase activation and apoptosis

PubMed Central

Saidani, Chanez; Hammoudi-Triki, Djelila; Laraba-Djebari, Fatima; Taub, Mary

2016-01-01

Scorpion envenomation injures a number of organs, including the kidney. Mechanisms proposed to explain the renal tubule injury include direct effects of venom on tubule epithelial cells, as well as indirect effects of the autonomic nervous system, and inflammation. Here, we report direct effects of Androctonus australis hector (Aah) scorpion venom on the viability of Renal Proximal Tubule (RPT) cells in vitro, unlike distal tubule and collecting duct cells. Extensive NucGreen nuclear staining was observed in immortalized rabbit RPT cells following treatment with Aah venom, consistent with cytotoxicity. The involvement of oxidative stress is supported by the observations that 1) anti-oxidants mitigated the Aah venom-induced decrease in the number of viable RPT cells, and 2) Aah venom-treated RPT cells were intensively stained with the CellROX® Deep Red reagent, an indicator of Reactive Oxygen Species (ROS). Relevance to normal RPT cells is supported by the red fluorescence observed in Aah venom treated primary rabbit RPT cell cultures following their incubation with the Flica reagent (indicative of caspase activation and apoptosis), and the green fluorescence of Sytox Green (indicative of dead cells). PMID:27470530

In vitro studies with renal proximal tubule cells show direct cytotoxicity of Androctonus australis hector scorpion venom triggered by oxidative stress, caspase activation and apoptosis.

PubMed

Saidani, Chanez; Hammoudi-Triki, Djelila; Laraba-Djebari, Fatima; Taub, Mary

2016-09-15

Scorpion envenomation injures a number of organs, including the kidney. Mechanisms proposed to explain the renal tubule injury include direct effects of venom on tubule epithelial cells, as well as indirect effects of the autonomic nervous system, and inflammation. Here, we report direct effects of Androctonus australis hector (Aah) scorpion venom on the viability of Renal Proximal Tubule (RPT) cells in vitro, unlike distal tubule and collecting duct cells. Extensive NucGreen nuclear staining was observed in immortalized rabbit RPT cells following treatment with Aah venom, consistent with cytotoxicity. The involvement of oxidative stress is supported by the observations that 1) anti-oxidants mitigated the Aah venom-induced decrease in the number of viable RPT cells, and 2) Aah venom-treated RPT cells were intensively stained with the CellROX(®) Deep Red reagent, an indicator of Reactive Oxygen Species (ROS). Relevance to normal RPT cells is supported by the red fluorescence observed in Aah venom treated primary rabbit RPT cell cultures following their incubation with the Flica reagent (indicative of caspase activation and apoptosis), and the green fluorescence of Sytox Green (indicative of dead cells). Copyright © 2016 Elsevier Ltd. All rights reserved.

Proteasome phosphorylation regulates cocaine-induced sensitization.

PubMed

Gonzales, Frankie R; Howell, Kristin K; Dozier, Lara E; Anagnostaras, Stephan G; Patrick, Gentry N

2018-04-01

Repeated exposure to cocaine produces structural and functional modifications at synapses from neurons in several brain regions including the nucleus accumbens. These changes are thought to underlie cocaine-induced sensitization. The ubiquitin proteasome system plays a crucial role in the remodeling of synapses and has recently been implicated in addiction-related behavior. The ATPase Rpt6 subunit of the 26S proteasome is phosphorylated by Ca 2+ /calmodulin-dependent protein kinases II alpha at ser120 which is thought to regulate proteasome activity and distribution in neurons. Here, we demonstrate that Rpt6 phosphorylation is involved in cocaine-induced locomotor sensitization. Cocaine concomitantly increases proteasome activity and Rpt6 S120 phosphorylation in cultured neurons and in various brain regions of wild type mice including the nucleus accumbens and prefrontal cortex. In contrast, cocaine does not increase proteasome activity in Rpt6 phospho-mimetic (ser120Asp) mice. Strikingly, we found a complete absence of cocaine-induced locomotor sensitization in the Rpt6 ser120Asp mice. Together, these findings suggest a critical role for Rpt6 phosphorylation and proteasome function in the regulation cocaine-induced behavioral plasticity. Copyright © 2017 Elsevier Inc. All rights reserved.

13 CFR 120.830 - Reports a CDC must submit.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 13 Business Credit and Assistance 1 2014-01-01 2014-01-01 false Reports a CDC must submit. 120.830... Company Loan Program (504) Requirements for Cdc Certification and Operation § 120.830 Reports a CDC must submit. A CDC must submit the following reports to SBA: (a) An annual report within one hundred-eighty...

13 CFR 120.830 - Reports a CDC must submit.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 13 Business Credit and Assistance 1 2013-01-01 2013-01-01 false Reports a CDC must submit. 120.830... Company Loan Program (504) Requirements for Cdc Certification and Operation § 120.830 Reports a CDC must submit. A CDC must submit the following reports to SBA: (a) An annual report within one hundred-eighty...

13 CFR 120.830 - Reports a CDC must submit.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 13 Business Credit and Assistance 1 2011-01-01 2011-01-01 false Reports a CDC must submit. 120.830... Company Loan Program (504) Requirements for Cdc Certification and Operation § 120.830 Reports a CDC must submit. A CDC must submit the following reports to SBA: (a) An annual report within one hundred-eighty...

13 CFR 120.830 - Reports a CDC must submit.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 13 Business Credit and Assistance 1 2012-01-01 2012-01-01 false Reports a CDC must submit. 120.830... Company Loan Program (504) Requirements for Cdc Certification and Operation § 120.830 Reports a CDC must submit. A CDC must submit the following reports to SBA: (a) An annual report within one hundred-eighty...

77 FR 44267 - Notice of Availability of the Final Programmatic Environmental Impact Statement for Solar Energy...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-27

... Final EIS NOA and use them to inform the Records of Decision. Those individuals wishing to submit... general information regarding the DOE NEPA process, contact Carol Borgstrom, Director, Office of NEPA... development. Through the Final Programmatic EIS, the BLM is considering replacing elements of its existing...

47 CFR 1.10017 - How can I submit additional information?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 1 2010-10-01 2010-10-01 false How can I submit additional information? 1... International Bureau Filing System § 1.10017 How can I submit additional information? In response to an official request for information from the International Bureau, you can submit additional information...

40 CFR 35.105 - Time frame for submitting an application.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Time frame for submitting an application. 35.105 Section 35.105 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER....105 Time frame for submitting an application. An applicant should submit a complete application to EPA...

40 CFR 35.506 - Time frame for submitting an application.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Time frame for submitting an application. 35.506 Section 35.506 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER... Application § 35.506 Time frame for submitting an application. An applicant should submit a complete...

29 CFR 1956.21 - Procedures for submitting changes.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 9 2010-07-01 2010-07-01 false Procedures for submitting changes. 1956.21 Section 1956.21 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION..., Change, Evaluation and Withdrawal of Approval Procedures § 1956.21 Procedures for submitting changes. The...

30 CFR 210.203 - How do I submit sales contracts?

Code of Federal Regulations, 2010 CFR

2010-07-01

... royalty terms. (b) When to submit. (1) For coal and metal production, you must submit the required... MANAGEMENT FORMS AND REPORTS Production and Royalty Reports-Solid Minerals § 210.203 How do I submit sales..., and phosphate production, and production from any other lease with ad valorem royalty terms, you must...

Intraoperative neurophysiological responses in epileptic patients submitted to hippocampal and thalamic deep brain stimulation.

PubMed

Cukiert, Arthur; Cukiert, Cristine Mella; Argentoni-Baldochi, Meire; Baise, Carla; Forster, Cássio Roberto; Mello, Valeria Antakli; Burattini, José Augusto; Lima, Alessandra Moura

2011-12-01

Deep brain stimulation (DBS) has been used in an increasing frequency for treatment of refractory epilepsy. Acute deep brain macrostimulation intraoperative findings were sparsely published in the literature. We report on our intraoperative macrostimulation findings during thalamic and hippocampal DBS implantation. Eighteen patients were studied. All patients underwent routine pre-operative evaluation that included clinical history, neurological examination, interictal and ictal EEG, high resolution 1.5T MRI and neuropsychological testing. Six patients with temporal lobe epilepsy were submitted to hippocampal DBS (Hip-DBS); 6 patients with focal epilepsy were submitted to anterior thalamic nucleus DBS (AN-DBS) and 6 patients with generalized epilepsy were submitted to centro-median thalamic nucleus DBS (CM-DBS). Age ranged from 9 to 40 years (11 males). All patients were submitted to bilateral quadripolar DBS electrode implantation in a single procedure, under general anesthesia, and intraoperative scalp EEG monitoring. Final electrode's position was checked postoperatively using volumetric CT scanning. Bipolar stimulation using the more proximal and distal electrodes was performed. Final standard stimulation parameters were 6Hz, 4V, 300μs (low frequency range: LF) or 130Hz, 4V, 300μs (high frequency range: HF). Bilateral recruiting response (RR) was obtained after unilateral stimulation in all patients submitted to AN and CM-DBS using LF stimulation. RR was widespread but prevailed over the fronto-temporal region bilaterally, and over the stimulated hemisphere. HF stimulation led to background slowing and a DC shift. The mean voltage for the appearance of RR was 4V (CM) and 3V (AN). CM and AN-DBS did not alter inter-ictal spiking frequency or morphology. RR obtained after LF Hip-DBS was restricted to the stimulated temporal lobe and no contralateral activation was noted. HF stimulation yielded no visually recognizable EEG modification. Mean intensity for initial

42 CFR 102.43 - Deadlines for submitting documentation.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 1 2014-10-01 2014-10-01 false Deadlines for submitting documentation. 102.43 Section 102.43 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES VACCINES SMALLPOX COMPENSATION PROGRAM Procedures for Filing Request Packages § 102.43 Deadlines for submitting...

42 CFR 102.43 - Deadlines for submitting documentation.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 1 2011-10-01 2011-10-01 false Deadlines for submitting documentation. 102.43 Section 102.43 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES VACCINES SMALLPOX COMPENSATION PROGRAM Procedures for Filing Request Packages § 102.43 Deadlines for submitting...

42 CFR 102.43 - Deadlines for submitting documentation.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 1 2012-10-01 2012-10-01 false Deadlines for submitting documentation. 102.43 Section 102.43 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES VACCINES SMALLPOX COMPENSATION PROGRAM Procedures for Filing Request Packages § 102.43 Deadlines for submitting...

42 CFR 102.43 - Deadlines for submitting documentation.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 1 2013-10-01 2013-10-01 false Deadlines for submitting documentation. 102.43 Section 102.43 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES VACCINES SMALLPOX COMPENSATION PROGRAM Procedures for Filing Request Packages § 102.43 Deadlines for submitting...

42 CFR 102.43 - Deadlines for submitting documentation.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Deadlines for submitting documentation. 102.43 Section 102.43 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES VACCINES SMALLPOX COMPENSATION PROGRAM Procedures for Filing Request Packages § 102.43 Deadlines for submitting...

Office of Inspector General; Medicare and state health care programs: fraud and abuse; issuance of advisory opinions by the OIG. Final rule.

PubMed

2008-07-17

OIG is adopting in final form, without change, an interim final rule published on March 26, 2008 (73 FR 15937). We received no comments to the interim final rule. The interim final rule revised the process for advisory opinion requestors to submit payments for advisory opinion costs.

12 CFR 516.110 - Who may submit a written comment?

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Who may submit a written comment? 516.110 Section 516.110 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY APPLICATION PROCESSING PROCEDURES Comment Procedures § 516.110 Who may submit a written comment? Any person may submit a...

25 CFR 183.15 - Must the Tribe submit any reports?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Must the Tribe submit any reports? 183.15 Section 183.15... SAN CARLOS APACHE TRIBE DEVELOPMENT TRUST FUND AND SAN CARLOS APACHE TRIBE LEASE FUND Reports § 183.15 Must the Tribe submit any reports? Yes. The Tribe must submit the following reports after receiving...

25 CFR 183.15 - Must the Tribe submit any reports?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 1 2013-04-01 2013-04-01 false Must the Tribe submit any reports? 183.15 Section 183.15... SAN CARLOS APACHE TRIBE DEVELOPMENT TRUST FUND AND SAN CARLOS APACHE TRIBE LEASE FUND Reports § 183.15 Must the Tribe submit any reports? Yes. The Tribe must submit the following reports after receiving...

25 CFR 183.15 - Must the Tribe submit any reports?

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 1 2012-04-01 2011-04-01 true Must the Tribe submit any reports? 183.15 Section 183.15... SAN CARLOS APACHE TRIBE DEVELOPMENT TRUST FUND AND SAN CARLOS APACHE TRIBE LEASE FUND Reports § 183.15 Must the Tribe submit any reports? Yes. The Tribe must submit the following reports after receiving...

25 CFR 183.15 - Must the Tribe submit any reports?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 1 2014-04-01 2014-04-01 false Must the Tribe submit any reports? 183.15 Section 183.15... SAN CARLOS APACHE TRIBE DEVELOPMENT TRUST FUND AND SAN CARLOS APACHE TRIBE LEASE FUND Reports § 183.15 Must the Tribe submit any reports? Yes. The Tribe must submit the following reports after receiving...

25 CFR 183.15 - Must the Tribe submit any reports?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 1 2011-04-01 2011-04-01 false Must the Tribe submit any reports? 183.15 Section 183.15... SAN CARLOS APACHE TRIBE DEVELOPMENT TRUST FUND AND SAN CARLOS APACHE TRIBE LEASE FUND Reports § 183.15 Must the Tribe submit any reports? Yes. The Tribe must submit the following reports after receiving...

Construct Validity of the Relationship Profile Test: Links with measures of psychopathology and adult attachment

PubMed Central

Haggerty, Greg; Bornstein, Robert F.; Khalid, Mohammad; Sharma, Vishal; Riaz, Usman; Blanchard, Mark; Siefert, Caleb J; Sinclair, Samuel J.

2015-01-01

This study assessed the construct validity of the Relationship Profile Test (RPT; Bornstein & Languirand, 2003) with a substance abuse sample. One hundred-eight substance abuse patients completed the RPT, Experiences in Close Relationships Scale (ECR-SF; Wei, Russell, Mallinckrodt, & Vogel, 2007), Personality Assessment Inventory (PAI; Morey, 1991), and Symptom Checklist-90-Revised (SCL-90-R: Derogatis 1983). Results suggest that the RPT has good construct validity when compared against theoretically related broadband measures of personality, psychopathology and adult attachment. Overall, health hependency was negatively related to measures of psychopathology and insecure attachment, and overdependence was positively related to measures of psychopathology and attachment anxiety. Many of the predictions regarding RPT detachment and the criterion measures were not supported. Implications of these findings are discussed. PMID:26620463

24 CFR 902.62 - Failure to submit data.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 4 2013-04-01 2013-04-01 false Failure to submit data. 902.62... DEVELOPMENT PUBLIC HOUSING ASSESSMENT SYSTEM PHAS Scoring § 902.62 Failure to submit data. (a) Failure to... receive a presumptive rating of failure for its unaudited information and shall receive zero points for...

24 CFR 902.62 - Failure to submit data.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false Failure to submit data. 902.62... DEVELOPMENT PUBLIC HOUSING ASSESSMENT SYSTEM PHAS Scoring § 902.62 Failure to submit data. (a) Failure to... receive a presumptive rating of failure for its unaudited information and shall receive zero points for...

24 CFR 902.62 - Failure to submit data.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 4 2014-04-01 2014-04-01 false Failure to submit data. 902.62... DEVELOPMENT PUBLIC HOUSING ASSESSMENT SYSTEM PHAS Scoring § 902.62 Failure to submit data. (a) Failure to... receive a presumptive rating of failure for its unaudited information and shall receive zero points for...

30 CFR 285.607 - How do I submit my SAP?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How do I submit my SAP? 285.607 Section 285.607... Assessment Plan and Information Requirements for Commercial Leases § 285.607 How do I submit my SAP? You must submit one paper copy and one electronic version of your SAP to MMS at the address listed in § 285.110(a). ...

Interplay between autophagy and apoptosis in lead(II)-induced cytotoxicity of primary rat proximal tubular cells.

PubMed

Chu, Bing-Xin; Fan, Rui-Feng; Lin, Shu-Qian; Yang, Du-Bao; Wang, Zhen-Yong; Wang, Lin

2018-05-01

Autophagy and apoptosis are two different biological processes that determine cell fates. We previously reported that autophagy inhibition and apoptosis induction are involved in lead(II)-induced cytotoxicity in primary rat proximal tubular (rPT) cells, but the interplay between them remains to be elucidated. Firstly, data showed that lead(II)-induced elevation of LC3-II protein levels can be significantly modulated by 3-methyladenine or rapamycin; moreover, protein levels of Autophagy-related protein 5 (Atg5) and Beclin-1 were markedly up-regulated by lead(II) treatment, demonstrating that lead(II) could promote the autophagosomes formation in rPT cells. Next, we applied three pharmacological agents and genetic method targeting the early stage of autophagy to validate that enhancement of autophagosomes formation can inhibit lead(II)-induced apoptotic cell death in rPT cells. Simultaneously, lead(II) inhibited the autophagic degradation of rPT cells, while the addition of autophagic degradation inhibitor bafilomycin A1 aggravated lead(II)-induced apoptotic death in rPT cells. Collectively, this study provided us a good model to know about the dynamic process of lead(II)-induced autophagy in rPT cells, and the interplay between autophagy and apoptosis highlights a new sight into the mechanism of lead(II)-induced nephrotoxicity. Copyright © 2018. Published by Elsevier Inc.

A Checklist for Submitting Your Risk Management Plan (RMP)

EPA Pesticide Factsheets

Important information about 2014 submissions and a checklist to consider in preparing and resubmitting a 5-year update, as required by 40 CFR part 68. Use the RMP*eSubmit software application, which replaced RMP*Submit.

42 CFR 405.809 - Opportunity to submit evidence.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 2 2010-10-01 2010-10-01 false Opportunity to submit evidence. 405.809 Section 405.809 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM FEDERAL HEALTH INSURANCE FOR THE AGED AND DISABLED Appeals Under the Medicare Part B Program § 405.809 Opportunity to submit...

RMP*eSubmit User's Manual

EPA Pesticide Factsheets

RMP*eSubmit facilitates secure online Risk Management Plan updates/resubmissions, required at least every 5 years. Reporting requirements have not changed since 2004, but the 2012 version of North American Industry Classification System has been integrated

27 CFR 73.31 - May I submit forms electronically to TTB?

Code of Federal Regulations, 2014 CFR

2014-04-01

...; ELECTRONIC SUBMISSION OF FORMS Electronic Filing of Documents with TTB § 73.31 May I submit forms... above; (c) You submit the electronic form to an electronic document receiving system that we have... submit the form through an electronic document receiving system that TTB has designated for the receipt...

11 CFR 111.38 - Can the respondent appeal the Commission's final determination?

Code of Federal Regulations, 2010 CFR

2010-01-01

... 11 Federal Elections 1 2010-01-01 2010-01-01 false Can the respondent appeal the Commission's final determination? 111.38 Section 111.38 Federal Elections FEDERAL ELECTION COMMISSION GENERAL... determination under 11 CFR 111.37, the respondent may submit a written petition to the district court of the...

25 CFR 224.54 - How must a tribe submit an application?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 1 2014-04-01 2014-04-01 false How must a tribe submit an application? 224.54 Section... Obtaining Tribal Energy Resource Agreements Processing Applications § 224.54 How must a tribe submit an application? A tribe must submit an application and all supporting documents in written and electronic form to...

25 CFR 224.54 - How must a tribe submit an application?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 1 2013-04-01 2013-04-01 false How must a tribe submit an application? 224.54 Section... Obtaining Tribal Energy Resource Agreements Processing Applications § 224.54 How must a tribe submit an application? A tribe must submit an application and all supporting documents in written and electronic form to...

25 CFR 224.54 - How must a tribe submit an application?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 1 2011-04-01 2011-04-01 false How must a tribe submit an application? 224.54 Section... Obtaining Tribal Energy Resource Agreements Processing Applications § 224.54 How must a tribe submit an application? A tribe must submit an application and all supporting documents in written and electronic form to...

24 CFR 598.300 - Procedure for submitting a nomination.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 3 2014-04-01 2013-04-01 true Procedure for submitting a nomination. 598.300 Section 598.300 Housing and Urban Development Regulations Relating to Housing and Urban... DESIGNATIONS Designation Process § 598.300 Procedure for submitting a nomination. (a) Establishment of...

24 CFR 598.300 - Procedure for submitting a nomination.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 3 2013-04-01 2013-04-01 false Procedure for submitting a nomination. 598.300 Section 598.300 Housing and Urban Development Regulations Relating to Housing and Urban... DESIGNATIONS Designation Process § 598.300 Procedure for submitting a nomination. (a) Establishment of...

24 CFR 598.300 - Procedure for submitting a nomination.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 3 2012-04-01 2012-04-01 false Procedure for submitting a nomination. 598.300 Section 598.300 Housing and Urban Development Regulations Relating to Housing and Urban... DESIGNATIONS Designation Process § 598.300 Procedure for submitting a nomination. (a) Establishment of...

Identification and Characterization of MicroRNAs from Longitudinal Muscle and Respiratory Tree in Sea Cucumber (Apostichopus japonicus) Using High-Throughput Sequencing.

PubMed

Wang, Hongdi; Liu, Shikai; Cui, Jun; Li, Chengze; Hu, Yucai; Zhou, Wei; Chang, Yaqing; Qiu, Xuemei; Liu, Zhanjiang; Wang, Xiuli

2015-01-01

MicroRNAs (miRNAs), as a family of non-coding small RNAs, play important roles in the post-transcriptional regulation of gene expression. Sea cucumber (Apostichopus japonicus) is an important economic species which is widely cultured in East Asia. The longitudinal muscle (LTM) and respiratory tree (RPT) are two important tissues in sea cucumber, playing important roles such as respiration and movement. In this study, we identified and characterized miRNAs in the LTM and RPT of sea cucumber (Apostichopus japonicus) using Illumina HiSeq 2000 platform. A total of 314 and 221 conserved miRNAs were identified in LTM and RPT, respectively. In addition, 27 and 34 novel miRNAs were identified in the LTM and RPT, respectively. A set of 58 miRNAs were identified to be differentially expressed between LTM and RPT. Among them, 9 miRNAs (miR-31a-3p, miR-738, miR-1692, let-7a, miR-72a, miR-100b-5p, miR-31b-5p, miR-429-3p, and miR-2008) in RPT and 7 miRNAs (miR-127, miR-340, miR-381, miR-3543, miR-434-5p, miR-136-3p, and miR-300-3p) in LTM were differentially expressed with foldchange value being greater than 10. A total of 14,207 and 12,174 target genes of these miRNAs were predicted, respectively. Functional analysis of these target genes of miRNAs were performed by GO analysis and pathway analysis. This result provided in this work will be useful for understanding biological characteristics of the LTM and RPT of sea cucumber and assisting molecular breeding of sea cucumber for aquaculture.

45 CFR 149.320 - Universe of claims that must be submitted.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 45 Public Welfare 1 2012-10-01 2012-10-01 false Universe of claims that must be submitted. 149.320 Section 149.320 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH... Universe of claims that must be submitted. (a) Claims submitted for an early retiree, as defined in § 149.2...

45 CFR 149.320 - Universe of claims that must be submitted.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 45 Public Welfare 1 2014-10-01 2014-10-01 false Universe of claims that must be submitted. 149.320 Section 149.320 Public Welfare Department of Health and Human Services REQUIREMENTS RELATING TO HEALTH... Universe of claims that must be submitted. (a) Claims submitted for an early retiree, as defined in § 149.2...

45 CFR 149.320 - Universe of claims that must be submitted.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 45 Public Welfare 1 2013-10-01 2013-10-01 false Universe of claims that must be submitted. 149.320 Section 149.320 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH... Universe of claims that must be submitted. (a) Claims submitted for an early retiree, as defined in § 149.2...

45 CFR 149.320 - Universe of claims that must be submitted.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 1 2011-10-01 2011-10-01 false Universe of claims that must be submitted. 149.320 Section 149.320 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH... Universe of claims that must be submitted. (a) Claims submitted for an early retiree, as defined in § 149.2...

25 CFR 224.54 - How must a tribe submit an application?

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 1 2012-04-01 2011-04-01 true How must a tribe submit an application? 224.54 Section 224... Obtaining Tribal Energy Resource Agreements Processing Applications § 224.54 How must a tribe submit an application? A tribe must submit an application and all supporting documents in written and electronic form to...

30 CFR 218.580 - When do I submit Form MMS-4444?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false When do I submit Form MMS-4444? 218.580 Section 218.580 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE... Correspondence § 218.580 When do I submit Form MMS-4444? Initially, you must submit MMS Form-4444 by November 29...

Arabidopsis ROOT PHOTOTROPISM2 Contributes to the Adaptation to High-Intensity Light in Phototropic Responses

PubMed Central

Haga, Ken; Tsuchida-Mayama, Tomoko; Yamada, Mizuki; Sakai, Tatsuya

2015-01-01

Living organisms adapt to changing light environments via mechanisms that enhance photosensitivity under darkness and attenuate photosensitivity under bright light conditions. In hypocotyl phototropism, phototropin1 (phot1) blue light photoreceptors mediate both the pulse light-induced, first positive phototropism and the continuous light-induced, second positive phototropism, suggesting the existence of a mechanism that alters their photosensitivity. Here, we show that light induction of ROOT PHOTOTROPISM2 (RPT2) underlies photosensory adaptation in hypocotyl phototropism of Arabidopsis thaliana. rpt2 loss-of-function mutants exhibited increased photosensitivity to very low fluence blue light but were insensitive to low fluence blue light. Expression of RPT2 prior to phototropic stimulation in etiolated seedlings reduced photosensitivity during first positive phototropism and accelerated second positive phototropism. Our microscopy and biochemical analyses indicated that blue light irradiation causes dephosphorylation of NONPHOTOTROPIC HYPOCOTYL3 (NPH3) proteins and mediates their release from the plasma membrane. These phenomena correlate closely with the desensitization of phot1 signaling during the transition period from first positive phototropism to second positive phototropism. RPT2 modulated the phosphorylation of NPH3 and promoted reconstruction of the phot1-NPH3 complex on the plasma membrane. We conclude that photosensitivity is increased in the absence of RPT2 and that this results in the desensitization of phot1. Light-mediated induction of RPT2 then reduces the photosensitivity of phot1, which is required for second positive phototropism under bright light conditions. PMID:25873385

Requesting Different Nodes Types When Submitting Jobs on the Peregrine

Science.gov Websites

System | High-Performance Computing | NREL Requesting Different Nodes Types When Submitting Jobs on the Peregrine System Requesting Different Nodes Types When Submitting Jobs on the Peregrine

49 CFR 579.6 - Address for submitting reports and other information.

Code of Federal Regulations, 2014 CFR

2014-10-01

..., submissions under subpart B of this part must be submitted to [email protected]gov and submissions under § 579.5 must be submitted to [email protected]gov. (b)(1) Information, documents and reports that are submitted to NHTSA... identified on NHTSA's Web page http://www-odi.nhtsa.dot.gov/ewr/ewr.cfm. A manufacturer shall use the...

30 CFR 1218.580 - When do I submit Form ONRR-4444?

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 3 2014-07-01 2014-07-01 false When do I submit Form ONRR-4444? 1218.580... Service of Official Correspondence § 1218.580 When do I submit Form ONRR-4444? Initially, you must submit Form ONRR-4444 by November 29, 2006, and subsequently, within 2 weeks of any change of your address. ...

30 CFR 1218.580 - When do I submit Form MMS-4444?

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 3 2012-07-01 2012-07-01 false When do I submit Form MMS-4444? 1218.580... Service of Official Correspondence § 1218.580 When do I submit Form MMS-4444? Initially, you must submit Form MMS-4444 by November 29, 2006, and subsequently, within 2 weeks of any change of your address. ...

30 CFR 1218.580 - When do I submit Form MMS-4444?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 3 2011-07-01 2011-07-01 false When do I submit Form MMS-4444? 1218.580... Service of Official Correspondence § 1218.580 When do I submit Form MMS-4444? Initially, you must submit Form MMS-4444 by November 29, 2006, and subsequently, within 2 weeks of any change of your address. ...

30 CFR 1218.580 - When do I submit Form ONRR-4444?

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 3 2013-07-01 2013-07-01 false When do I submit Form ONRR-4444? 1218.580... Service of Official Correspondence § 1218.580 When do I submit Form ONRR-4444? Initially, you must submit Form ONRR-4444 by November 29, 2006, and subsequently, within 2 weeks of any change of your address. ...

30 CFR 210.51 - Who must submit royalty reports?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Who must submit royalty reports? 210.51 Section 210.51 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT FORMS AND REPORTS Royalty Reports-Oil, Gas, and Geothermal Resources § 210.51 Who must submit...

31 CFR 356.14 - What are the requirements for submitting bids for customers?

Code of Federal Regulations, 2010 CFR

2010-07-01

... submitting bids for customers? 356.14 Section 356.14 Money and Finance: Treasury Regulations Relating to... requirements for submitting bids for customers? (a) Institutions that may submit bids for customers. Only depository institutions or dealers may submit bids for customers (see definitions at § 356.2), or for...

44 CFR 65.3 - Requirement to submit new technical data.

Code of Federal Regulations, 2011 CFR

2011-10-01

... available, a community shall notify the Administrator of the changes by submitting technical or scientific... IDENTIFICATION AND MAPPING OF SPECIAL HAZARD AREAS § 65.3 Requirement to submit new technical data. A community's...

10 CFR 600.504 - Information an applicant must submit.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Information an applicant must submit. 600.504 Section 600... Information an applicant must submit. (a) Any applicant for financial assistance under a covered program shall... United States of products resulting from a technology developed with financial assistance or to procure...

10 CFR 600.504 - Information an applicant must submit.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Information an applicant must submit. 600.504 Section 600... Information an applicant must submit. (a) Any applicant for financial assistance under a covered program shall... United States of products resulting from a technology developed with financial assistance or to procure...

10 CFR 600.504 - Information an applicant must submit.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Information an applicant must submit. 600.504 Section 600... Information an applicant must submit. (a) Any applicant for financial assistance under a covered program shall... United States of products resulting from a technology developed with financial assistance or to procure...

40 CFR 98.5 - How is the report submitted?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 20 2010-07-01 2010-07-01 false How is the report submitted? 98.5 Section 98.5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING General Provision § 98.5 How is the report submitted? Each GHG report and...

7 CFR 3406.21 - Intent to submit a proposal.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Submission of a Teaching or Research Proposal § 3406.21 Intent to submit a proposal. To assist CSREES in... 7 Agriculture 15 2010-01-01 2010-01-01 false Intent to submit a proposal. 3406.21 Section 3406.21 Agriculture Regulations of the Department of Agriculture (Continued) COOPERATIVE STATE RESEARCH, EDUCATION...

40 CFR 60.4915 - What reports must I submit?

Code of Federal Regulations, 2013 CFR

2013-07-01

... Electronic Reporting Tool (ERT) (see http://www.epa.gov/ttn/chief/ert/ert_tool.html/) or other compatible... Sludge Incineration Units Recordkeeping and Reporting § 60.4915 What reports must I submit? You must... reporting period specified in paragraph (d)(3) of this section. You must submit your first annual compliance...

40 CFR 60.4915 - What reports must I submit?

Code of Federal Regulations, 2014 CFR

2014-07-01

... Electronic Reporting Tool (ERT) (see http://www.epa.gov/ttn/chief/ert/ert_tool.html/) or other compatible... Sludge Incineration Units Recordkeeping and Reporting § 60.4915 What reports must I submit? You must... reporting period specified in paragraph (d)(3) of this section. You must submit your first annual compliance...

7 CFR 3405.12 - Intent to submit a proposal.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 15 2012-01-01 2012-01-01 false Intent to submit a proposal. 3405.12 Section 3405.12 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL INSTITUTE OF FOOD AND AGRICULTURE HIGHER EDUCATION CHALLENGE GRANTS PROGRAM Submission of a Proposal § 3405.12 Intent to submit a...

7 CFR 3405.12 - Intent to submit a proposal.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 15 2013-01-01 2013-01-01 false Intent to submit a proposal. 3405.12 Section 3405.12 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL INSTITUTE OF FOOD AND AGRICULTURE HIGHER EDUCATION CHALLENGE GRANTS PROGRAM Submission of a Proposal § 3405.12 Intent to submit a...

7 CFR 3405.12 - Intent to submit a proposal.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 15 2014-01-01 2014-01-01 false Intent to submit a proposal. 3405.12 Section 3405.12 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL INSTITUTE OF FOOD AND AGRICULTURE HIGHER EDUCATION CHALLENGE GRANTS PROGRAM Submission of a Proposal § 3405.12 Intent to submit a...

7 CFR 3405.12 - Intent to submit a proposal.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 15 2011-01-01 2011-01-01 false Intent to submit a proposal. 3405.12 Section 3405.12 Agriculture Regulations of the Department of Agriculture (Continued) NATIONAL INSTITUTE OF FOOD AND AGRICULTURE HIGHER EDUCATION CHALLENGE GRANTS PROGRAM Submission of a Proposal § 3405.12 Intent to submit a...

40 CFR 98.5 - How is the report submitted?

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 22 2013-07-01 2013-07-01 false How is the report submitted? 98.5 Section 98.5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING General Provision § 98.5 How is the report submitted? Each GHG report and...

40 CFR 98.5 - How is the report submitted?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 21 2011-07-01 2011-07-01 false How is the report submitted? 98.5 Section 98.5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING General Provision § 98.5 How is the report submitted? Each GHG report and...

40 CFR 98.5 - How is the report submitted?

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 22 2012-07-01 2012-07-01 false How is the report submitted? 98.5 Section 98.5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING General Provision § 98.5 How is the report submitted? Each GHG report and...

30 CFR 285.622 - How do I submit my COP?

Code of Federal Regulations, 2010 CFR

2010-07-01

... ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Plans and Information Requirements Construction and Operations Plan for Commercial Leases § 285.622 How do I submit my COP? (a) You must submit...

Program and Abstracts, Boron Americas IX Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Feakes, Debra A.

The Scientific and Technical Information (STI) submitted includes the final report and a collection of abstracts for the Ninth Boron in the Americas Conference which was held May 19-22, 2004, in San Marcos, Texas. The topics covered in the abstracts include: Application in Medicine, Application in Organic Synthesis and Catalysis, Boranes and Carboranes, Materials and Polymers, Metallaboranes and Metallacarboranes, Organoboron Compounds, Synthesis and Catalysis, and Theoretical Studies. Attendees represented researchers from government, industry, and academia.

46 CFR 110.25-3 - Procedure for submitting plans.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Procedure for submitting plans. 110.25-3 Section 110.25-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING GENERAL PROVISIONS Plan Submittal § 110.25-3 Procedure for submitting plans. (a) The plans required by § 110.25-1...

46 CFR 110.25-3 - Procedure for submitting plans.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 4 2011-10-01 2011-10-01 false Procedure for submitting plans. 110.25-3 Section 110.25-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING GENERAL PROVISIONS Plan Submittal § 110.25-3 Procedure for submitting plans. (a) The plans required by § 110.25-1...

46 CFR 110.25-3 - Procedure for submitting plans.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 4 2014-10-01 2014-10-01 false Procedure for submitting plans. 110.25-3 Section 110.25-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING GENERAL PROVISIONS Plan Submittal § 110.25-3 Procedure for submitting plans. (a) The plans required by § 110.25-1...

30 CFR 210.101 - Who must submit production reports?

Code of Federal Regulations, 2010 CFR

2010-07-01

... MANAGEMENT FORMS AND REPORTS Production Reports-Oil and Gas § 210.101 Who must submit production reports? (a... operator number. To obtain an operator number, refer to the MMS Minerals Production Reporter Handbook for... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Who must submit production reports? 210.101...

25 CFR 20.601 - How can applications be submitted?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false How can applications be submitted? 20.601 Section 20.601... SOCIAL SERVICES PROGRAMS Administrative Procedures § 20.601 How can applications be submitted? You can... you can get from your social services worker or tribe; or (b) Through an interview with a social...

7 CFR 3406.21 - Intent to submit a proposal.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AGRICULTURE 1890 INSTITUTION CAPACITY BUILDING GRANTS PROGRAM Submission of a Teaching or Research Proposal § 3406.21 Intent to submit a proposal. To assist CSREES in preparing for the review of proposals... 7 Agriculture 15 2011-01-01 2011-01-01 false Intent to submit a proposal. 3406.21 Section 3406.21...

46 CFR 110.25-3 - Procedure for submitting plans.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 4 2012-10-01 2012-10-01 false Procedure for submitting plans. 110.25-3 Section 110.25-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING GENERAL PROVISIONS Plan Submittal § 110.25-3 Procedure for submitting plans. (a) The plans required by § 110.25-1...

46 CFR 110.25-3 - Procedure for submitting plans.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 4 2013-10-01 2013-10-01 false Procedure for submitting plans. 110.25-3 Section 110.25-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING GENERAL PROVISIONS Plan Submittal § 110.25-3 Procedure for submitting plans. (a) The plans required by § 110.25-1...

18 CFR 1b.18 - Right to submit statements.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Right to submit statements. 1b.18 Section 1b.18 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES RELATING TO INVESTIGATIONS § 1b.18 Right to submit...

18 CFR 1b.18 - Right to submit statements.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Right to submit statements. 1b.18 Section 1b.18 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES RELATING TO INVESTIGATIONS § 1b.18 Right to submit...

18 CFR 1b.18 - Right to submit statements.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Right to submit statements. 1b.18 Section 1b.18 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES RELATING TO INVESTIGATIONS § 1b.18 Right to submit...

18 CFR 1b.18 - Right to submit statements.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Right to submit statements. 1b.18 Section 1b.18 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES RELATING TO INVESTIGATIONS § 1b.18 Right to submit...

18 CFR 1b.18 - Right to submit statements.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Right to submit statements. 1b.18 Section 1b.18 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES RULES RELATING TO INVESTIGATIONS § 1b.18 Right to submit...

77 FR 56714 - Agency Information Collection (Annual-Final Report and Account) Activities Under OMB Review

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-13

... DEPARTMENT OF VETERANS AFFAIRS [OMB Control No. 2900-0017] Agency Information Collection (Annual-Final Report and Account) Activities Under OMB Review AGENCY: Veterans Benefits Administration...), Department of Veterans Affairs, will submit the collection of information abstracted below to the Office of...

40 CFR 60.2900 - When must I submit my waste management plan?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 6 2010-07-01 2010-07-01 false When must I submit my waste management... Waste Management Plan § 60.2900 When must I submit my waste management plan? You must submit a waste management plan prior to commencing construction, reconstruction, or modification. ...

40 CFR 60.2900 - When must I submit my waste management plan?

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 7 2012-07-01 2012-07-01 false When must I submit my waste management... Waste Management Plan § 60.2900 When must I submit my waste management plan? You must submit a waste management plan prior to commencing construction, reconstruction, or modification. ...

40 CFR 60.2900 - When must I submit my waste management plan?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 6 2011-07-01 2011-07-01 false When must I submit my waste management... Waste Management Plan § 60.2900 When must I submit my waste management plan? You must submit a waste management plan prior to commencing construction, reconstruction, or modification. ...

Foundations for Success: The Final Report of the National Mathematics Advisory Panel

ERIC Educational Resources Information Center

US Department of Education, 2008

2008-01-01

On March 13, 2008, the National Mathematics Advisory Panel submitted its Final Report to the President of the United States and the Secretary of Education, and it was officially released to the public on that date, as well. The Panel agrees that the delivery system in mathematics education--the system that translates mathematical knowledge into…

30 CFR 254.53 - Submitting a response plan developed under State requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Submitting a response plan developed under....53 Submitting a response plan developed under State requirements. (a) You may submit a response plan... Federal officials and response personnel if there is a spill. (3) Identify any private personnel and...

Arabidopsis ROOT PHOTOTROPISM2 Contributes to the Adaptation to High-Intensity Light in Phototropic Responses.

PubMed

Haga, Ken; Tsuchida-Mayama, Tomoko; Yamada, Mizuki; Sakai, Tatsuya

2015-04-01

Living organisms adapt to changing light environments via mechanisms that enhance photosensitivity under darkness and attenuate photosensitivity under bright light conditions. In hypocotyl phototropism, phototropin1 (phot1) blue light photoreceptors mediate both the pulse light-induced, first positive phototropism and the continuous light-induced, second positive phototropism, suggesting the existence of a mechanism that alters their photosensitivity. Here, we show that light induction of ROOT PHOTOTROPISM2 (RPT2) underlies photosensory adaptation in hypocotyl phototropism of Arabidopsis thaliana. rpt2 loss-of-function mutants exhibited increased photosensitivity to very low fluence blue light but were insensitive to low fluence blue light. Expression of RPT2 prior to phototropic stimulation in etiolated seedlings reduced photosensitivity during first positive phototropism and accelerated second positive phototropism. Our microscopy and biochemical analyses indicated that blue light irradiation causes dephosphorylation of NONPHOTOTROPIC HYPOCOTYL3 (NPH3) proteins and mediates their release from the plasma membrane. These phenomena correlate closely with the desensitization of phot1 signaling during the transition period from first positive phototropism to second positive phototropism. RPT2 modulated the phosphorylation of NPH3 and promoted reconstruction of the phot1-NPH3 complex on the plasma membrane. We conclude that photosensitivity is increased in the absence of RPT2 and that this results in the desensitization of phot1. Light-mediated induction of RPT2 then reduces the photosensitivity of phot1, which is required for second positive phototropism under bright light conditions. © 2015 American Society of Plant Biologists. All rights reserved.

40 CFR 62.14715 - When must I submit my waste management plan?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 8 2010-07-01 2010-07-01 false When must I submit my waste management... submit my waste management plan? You must submit the waste management plan no later than April 5, 2004. ... POLLUTANTS Federal Plan Requirements for Commercial and Industrial Solid Waste Incineration Units That...

40 CFR 62.14715 - When must I submit my waste management plan?

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 9 2013-07-01 2013-07-01 false When must I submit my waste management... submit my waste management plan? You must submit the waste management plan no later than April 5, 2004. ... POLLUTANTS Federal Plan Requirements for Commercial and Industrial Solid Waste Incineration Units That...

40 CFR 62.14715 - When must I submit my waste management plan?

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 9 2014-07-01 2014-07-01 false When must I submit my waste management... submit my waste management plan? You must submit the waste management plan no later than April 5, 2004. ... POLLUTANTS Federal Plan Requirements for Commercial and Industrial Solid Waste Incineration Units That...

40 CFR 62.14715 - When must I submit my waste management plan?

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 9 2012-07-01 2012-07-01 false When must I submit my waste management... submit my waste management plan? You must submit the waste management plan no later than April 5, 2004. ... POLLUTANTS Federal Plan Requirements for Commercial and Industrial Solid Waste Incineration Units That...

40 CFR 62.14715 - When must I submit my waste management plan?

Code of Federal Regulations, 2011 CFR

2011-07-01

... POLLUTANTS Federal Plan Requirements for Commercial and Industrial Solid Waste Incineration Units That... 40 Protection of Environment 8 2011-07-01 2011-07-01 false When must I submit my waste management... submit my waste management plan? You must submit the waste management plan no later than April 5, 2004. ...

40 CFR 60.2060 - When must I submit my waste management plan?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 6 2010-07-01 2010-07-01 false When must I submit my waste management plan? 60.2060 Section 60.2060 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Management Plan § 60.2060 When must I submit my waste management plan? You must submit a waste management...

40 CFR 60.2060 - When must I submit my waste management plan?

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 7 2012-07-01 2012-07-01 false When must I submit my waste management plan? 60.2060 Section 60.2060 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Management Plan § 60.2060 When must I submit my waste management plan? You must submit a waste management...

40 CFR 60.2060 - When must I submit my waste management plan?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 6 2011-07-01 2011-07-01 false When must I submit my waste management plan? 60.2060 Section 60.2060 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Management Plan § 60.2060 When must I submit my waste management plan? You must submit a waste management...

40 CFR 60.2625 - When must I submit my waste management plan?

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 7 2012-07-01 2012-07-01 false When must I submit my waste management... Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Waste Management Plan § 60.2625 When must I submit my waste management plan? You must submit a waste management plan no...

40 CFR 60.2755 - When must I submit my waste management plan?

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 7 2012-07-01 2012-07-01 false When must I submit my waste management... Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Recordkeeping and Reporting § 60.2755 When must I submit my waste management plan? You must submit the waste management plan...

30 CFR 254.53 - Submitting a response plan developed under State requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 2 2012-07-01 2012-07-01 false Submitting a response plan developed under... of the Coast Line § 254.53 Submitting a response plan developed under State requirements. (a) You may submit a response plan to BSEE for approval that you developed in accordance with the laws or regulations...

30 CFR 254.53 - Submitting a response plan developed under State requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 2 2013-07-01 2013-07-01 false Submitting a response plan developed under... of the Coast Line § 254.53 Submitting a response plan developed under State requirements. (a) You may submit a response plan to BSEE for approval that you developed in accordance with the laws or regulations...

30 CFR 254.53 - Submitting a response plan developed under State requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Submitting a response plan developed under... Waters Seaward of the Coast Line § 254.53 Submitting a response plan developed under State requirements. (a) You may submit a response plan to MMS for approval that you developed in accordance with the laws...

30 CFR 254.53 - Submitting a response plan developed under State requirements.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 2 2014-07-01 2014-07-01 false Submitting a response plan developed under... of the Coast Line § 254.53 Submitting a response plan developed under State requirements. (a) You may submit a response plan to BSEE for approval that you developed in accordance with the laws or regulations...

Methodological Issues in Economic Evaluations Submitted to the Pan-Canadian Oncology Drug Review (pCODR).

PubMed

Masucci, Lisa; Beca, Jaclyn; Sabharwal, Mona; Hoch, Jeffrey S

2017-12-01

Public drug plans are faced with increasingly difficult funding decisions. In Canada, the pan-Canadian Oncology Drug Review (pCODR) makes funding recommendations to the provincial and territorial drug plans responsible for cancer drugs. Assessments of the economic models submitted by pharmaceutical manufacturers are publicly reported. The main objective of this research was to identify recurring methodological issues in economic models submitted to pCODR for funding reviews. The secondary objective was to explore whether there exists any observed relationships between reported methodological issues and funding recommendations made by pCODR's expert review committee. Publicly available Economic Guidance Reports from July 2011 (inception) until June 2014 for drug reviews with a final funding recommendation (N = 34) were independently examined by two authors. Major methodological issues from each review were abstracted and grouped into nine main categories. Each issue was also categorized based on perception of the reviewer's actions to manage it. The most commonly reported issues involved costing (59% of reviews), time horizon (56%), and model structure (36%). Several types of issues were identified that usually could not be resolved, such as quality of clinical data or uncertainty with indirect comparisons. Issues with costing or choice of utility estimates could usually be addressed or explored by reviewers. No statistically significant relationship was found between any methodological issue and funding recommendations from the expert review committee. The findings provide insights that can be used by parties who submit or review economic evidence for continuous improvement and consistency in economic modeling, reporting, and decision making.

45 CFR 2523.110 - Can Federal agencies submit multiple applications?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 4 2010-10-01 2010-10-01 false Can Federal agencies submit multiple applications? 2523.110 Section 2523.110 Public Welfare Regulations Relating to Public Welfare (Continued) CORPORATION... AMERICORPS PROGRAM ASSISTANCE § 2523.110 Can Federal agencies submit multiple applications? No. The...

40 CFR 62.14585 - When must I submit my waste management plan?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 8 2010-07-01 2010-07-01 false When must I submit my waste management... Commenced Construction On or Before November 30, 1999 Waste Management Plan § 62.14585 When must I submit my waste management plan? You must submit a waste management plan no later than April 5, 2004. ...

40 CFR 60.3011 - When must I submit my waste management plan?

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 7 2014-07-01 2014-07-01 false When must I submit my waste management... Model Rule-Waste Management Plan § 60.3011 When must I submit my waste management plan? You must submit a waste management plan no later than 60 days following the initial performance test as specified in...

40 CFR 62.14585 - When must I submit my waste management plan?

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 9 2014-07-01 2014-07-01 false When must I submit my waste management... Commenced Construction On or Before November 30, 1999 Waste Management Plan § 62.14585 When must I submit my waste management plan? You must submit a waste management plan no later than April 5, 2004. ...

40 CFR 60.3011 - When must I submit my waste management plan?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 6 2011-07-01 2011-07-01 false When must I submit my waste management... Model Rule-Waste Management Plan § 60.3011 When must I submit my waste management plan? You must submit a waste management plan no later than 60 days following the initial performance test as specified in...

40 CFR 60.2900 - When must I submit my waste management plan?

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 7 2014-07-01 2014-07-01 false When must I submit my waste management... Modification or Reconstruction is Commenced on or After June 16, 2006 Waste Management Plan § 60.2900 When must I submit my waste management plan? You must submit a waste management plan prior to commencing...

40 CFR 62.14585 - When must I submit my waste management plan?

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 9 2013-07-01 2013-07-01 false When must I submit my waste management... Commenced Construction On or Before November 30, 1999 Waste Management Plan § 62.14585 When must I submit my waste management plan? You must submit a waste management plan no later than April 5, 2004. ...

40 CFR 60.3011 - When must I submit my waste management plan?

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 7 2013-07-01 2013-07-01 false When must I submit my waste management... Model Rule-Waste Management Plan § 60.3011 When must I submit my waste management plan? You must submit a waste management plan no later than 60 days following the initial performance test as specified in...

40 CFR 60.2900 - When must I submit my waste management plan?

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 7 2013-07-01 2013-07-01 false When must I submit my waste management... Modification or Reconstruction is Commenced on or After June 16, 2006 Waste Management Plan § 60.2900 When must I submit my waste management plan? You must submit a waste management plan prior to commencing...

40 CFR 62.14585 - When must I submit my waste management plan?

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 9 2012-07-01 2012-07-01 false When must I submit my waste management... Commenced Construction On or Before November 30, 1999 Waste Management Plan § 62.14585 When must I submit my waste management plan? You must submit a waste management plan no later than April 5, 2004. ...

40 CFR 60.3011 - When must I submit my waste management plan?

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 7 2012-07-01 2012-07-01 false When must I submit my waste management... Model Rule-Waste Management Plan § 60.3011 When must I submit my waste management plan? You must submit a waste management plan no later than 60 days following the initial performance test as specified in...

40 CFR 60.3011 - When must I submit my waste management plan?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 6 2010-07-01 2010-07-01 false When must I submit my waste management... Times for Other Solid Waste Incineration Units That Commenced Construction On or Before December 9, 2004 Model Rule-Waste Management Plan § 60.3011 When must I submit my waste management plan? You must submit...

40 CFR 60.2625 - When must I submit my waste management plan?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 6 2011-07-01 2011-07-01 false When must I submit my waste management... or Before November 30, 1999 Model Rule-Waste Management Plan § 60.2625 When must I submit my waste management plan? You must submit a waste management plan no later than the date specified in table 1 of this...

21 CFR 803.13 - Do I need to submit reports in English?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Do I need to submit reports in English? 803.13... in English? (a) Yes. You must submit all written or electronic equivalent reports required by this part in English. (b) If you submit any reports required by this part in an electronic medium, that...

30 CFR 210.204 - How do I submit facility data?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 210.204 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR MINERALS REVENUE MANAGEMENT FORMS AND REPORTS Production and Royalty Reports-Solid Minerals § 210.204 How do I submit facility...) Output quality or product grades. (5) Your submitted facility data may be internally generated documents...

State-Administered Programs. Final Rule. Federal Register, Department of Education, 34 CFR Part 76

ERIC Educational Resources Information Center

National Archives and Records Administration, 2007

2007-01-01

The Secretary amends the regulations in 34 CFR part 76 governing State reporting requirements. These final regulations require States to submit their performance reports, financial reports, and any other required reports, in the manner prescribed by the Secretary, including through electronic submission, if the Secretary has obtained approval from…

29 CFR 1626.5 - Where to submit complaints and charges.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 29 Labor 4 2012-07-01 2012-07-01 false Where to submit complaints and charges. 1626.5 Section 1626.5 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURES-AGE DISCRIMINATION IN EMPLOYMENT ACT § 1626.5 Where to submit complaints and charges. Complaints and...

29 CFR 1626.5 - Where to submit complaints and charges.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 29 Labor 4 2013-07-01 2013-07-01 false Where to submit complaints and charges. 1626.5 Section 1626.5 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURES-AGE DISCRIMINATION IN EMPLOYMENT ACT § 1626.5 Where to submit complaints and charges. Complaints and...

29 CFR 1626.5 - Where to submit complaints and charges.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 4 2010-07-01 2010-07-01 false Where to submit complaints and charges. 1626.5 Section 1626.5 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURES-AGE DISCRIMINATION IN EMPLOYMENT ACT § 1626.5 Where to submit complaints and charges. Complaints and...

29 CFR 1626.5 - Where to submit complaints and charges.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 4 2011-07-01 2011-07-01 false Where to submit complaints and charges. 1626.5 Section 1626.5 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURES-AGE DISCRIMINATION IN EMPLOYMENT ACT § 1626.5 Where to submit complaints and charges. Complaints and...

29 CFR 1626.5 - Where to submit complaints and charges.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 29 Labor 4 2014-07-01 2014-07-01 false Where to submit complaints and charges. 1626.5 Section 1626.5 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURES-AGE DISCRIMINATION IN EMPLOYMENT ACT § 1626.5 Where to submit complaints and charges. Complaints and...

42 CFR 423.2018 - Submitting evidence before the ALJ hearing.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 3 2014-10-01 2014-10-01 false Submitting evidence before the ALJ hearing. 423.2018 Section 423.2018 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND... Reopening, ALJ Hearings, MAC review, and Judicial Review § 423.2018 Submitting evidence before the ALJ...

42 CFR 423.2018 - Submitting evidence before the ALJ hearing.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 3 2013-10-01 2013-10-01 false Submitting evidence before the ALJ hearing. 423.2018 Section 423.2018 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND... Reopening, ALJ Hearings, MAC review, and Judicial Review § 423.2018 Submitting evidence before the ALJ...

42 CFR 423.2018 - Submitting evidence before the ALJ hearing.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 3 2012-10-01 2012-10-01 false Submitting evidence before the ALJ hearing. 423.2018 Section 423.2018 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND... Reopening, ALJ Hearings, MAC review, and Judicial Review § 423.2018 Submitting evidence before the ALJ...

40 CFR 167.90 - Where to obtain and submit forms.

Code of Federal Regulations, 2010 CFR

2010-07-01

... establishments not found at the same location as their company headquarters, must submit applications and reports... establishments not found at the same location as their company headquarters to be submitted by the company headquarters to the Regional Office having jurisdiction over the State in which the company headquarters is...

21 CFR 1.279 - When must prior notice be submitted to FDA?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 1 2014-04-01 2014-04-01 false When must prior notice be submitted to FDA? 1.279... Imported Food § 1.279 When must prior notice be submitted to FDA? (a) Except as provided in paragraph (c) of this section, you must submit the prior notice to FDA and the prior notice submission must be...

21 CFR 1.279 - When must prior notice be submitted to FDA?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 1 2011-04-01 2011-04-01 false When must prior notice be submitted to FDA? 1.279... Imported Food § 1.279 When must prior notice be submitted to FDA? (a) Except as provided in paragraph (c) of this section, you must submit the prior notice to FDA and the prior notice submission must be...

21 CFR 1.279 - When must prior notice be submitted to FDA?

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 1 2012-04-01 2012-04-01 false When must prior notice be submitted to FDA? 1.279... Imported Food § 1.279 When must prior notice be submitted to FDA? (a) Except as provided in paragraph (c) of this section, you must submit the prior notice to FDA and the prior notice submission must be...

21 CFR 1.279 - When must prior notice be submitted to FDA?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 1 2010-04-01 2010-04-01 false When must prior notice be submitted to FDA? 1.279... Imported Food § 1.279 When must prior notice be submitted to FDA? (a) Except as provided in paragraph (c) of this section, you must submit the prior notice to FDA and the prior notice submission must be...

21 CFR 1.279 - When must prior notice be submitted to FDA?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 1 2013-04-01 2013-04-01 false When must prior notice be submitted to FDA? 1.279... Imported Food § 1.279 When must prior notice be submitted to FDA? (a) Except as provided in paragraph (c) of this section, you must submit the prior notice to FDA and the prior notice submission must be...

TRICARE; TRICARE sanction authority for third-party billing agents. Final rule.

PubMed

2013-02-26

This final rule will provide the Director, TRICARE Management Activity (TMA), or designee, with the authority to sanction third-party billing agents by invoking the administrative remedy of exclusion or suspension from the TRICARE program. Such sanctions may be invoked in situations involving fraud or abuse on the part of third-party billing agents that prepare or submit claims presented to TRICARE for payment.

42 CFR 423.2018 - Submitting evidence before the ALJ hearing.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 3 2011-10-01 2011-10-01 false Submitting evidence before the ALJ hearing. 423.2018 Section 423.2018 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND... Hearings, MAC review, and Judicial Review § 423.2018 Submitting evidence before the ALJ hearing. (a) All...

42 CFR 423.2018 - Submitting evidence before the ALJ hearing.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 3 2010-10-01 2010-10-01 false Submitting evidence before the ALJ hearing. 423.2018 Section 423.2018 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND... Hearings, MAC review, and Judicial Review § 423.2018 Submitting evidence before the ALJ hearing. (a) All...

31 CFR 375.12 - How do I submit an offer?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false How do I submit an offer? 375.12 Section 375.12 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL... way for any unauthorized tender submissions or for any delays, errors, or omissions in submitting...

20 CFR 416.802 - Type of evidence to be submitted.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Type of evidence to be submitted. 416.802 Section 416.802 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Determination of Age § 416.802 Type of evidence to be submitted. Where an...

77 FR 24403 - Direct Final Approval of Hospital/Medical/Infectious Waste Incinerators State Plan for Designated...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-24

.../Infectious Waste Incinerators'' (HMIWI). The Illinois Environmental Protection Agency (IEPA) submitted the... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 62 [EPA-R05-OAR-2012-0087; FRL-9663-4] Direct Final Approval of Hospital/Medical/Infectious Waste Incinerators State Plan for Designated Facilities and...

Permeability estimates in histopathology-proved treatment-induced necrosis using perfusion CT: can these add to other perfusion parameters in differentiating from recurrent/progressive tumors?

PubMed

Jain, R; Narang, J; Schultz, L; Scarpace, L; Saksena, S; Brown, S; Rock, J P; Rosenblum, M; Gutierrez, J; Mikkelsen, T

2011-04-01

Differentiating treatment effects from RPT is a common yet challenging task in a busy neuro-oncologic practice. PS probably represents a different aspect of angiogenesis and vasculature and can provide additional physiologic information about recurrent/progressive enhancing lesions. The purpose of the study was to use PS measured by using PCT to differentiate TIN from RPT in patients with previously irradiated brain tumor who presented with a recurrent/progressive enhancing lesion. Seventy-two patients underwent PCT for assessment of a recurrent/progressive enhancing lesion from January 2006 to November 2009. Thirty-eight patients who underwent surgery and histopathologic diagnosis were included in this analysis. Perfusion parameters such as PS, CBV, CBF, and MTT were obtained from the enhancing lesion as well as from the NAWM. Of 38 patients, 11 were diagnosed with pure TIN and 27 had RPT. Patients with TIN showed significantly lower mean PS values than those with RPT (1.8 ± 0.8 versus 3.6 ± 1.6 mL/100 g/min; P value=.001). The TIN group also showed lower rCBV (1.2 ± 0.3 versus 2.1 ± 0.7; P value<.001), lower rCBF (1.2 ± 0.5 versus 2.6 ± 1.7; P value=.004), and higher rMTT (1.4 ± 0.4 versus 1.0 ± 0.4; P value=.018) compared with the RPT group. PCT and particularly PS can be used in patients with previously treated brain tumors to differentiate TIN from RPT. PS estimates can help increase the accuracy of PCT in differentiating these 2 entities.

21 CFR 1.280 - How must you submit prior notice?

Code of Federal Regulations, 2010 CFR

2010-04-01

... to FDA. You must submit all prior notice information in the English language, except that an... Commercial System (ABI/ACS); or (2) The FDA PNSI at http://www.access.fda.gov. You must submit prior notice through the FDA Prior Notice System Interface (FDA PNSI) for articles of food imported or offered for...

41 CFR 105-50.401 - Reports submitted to the Congress.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 41 Public Contracts and Property Management 3 2012-01-01 2012-01-01 false Reports submitted to the Congress. 105-50.401 Section 105-50.401 Public Contracts and Property Management Federal Property... TECHNICAL SERVICES TO STATE AND LOCAL UNITS OF GOVERNMENT 50.4-Reports § 105-50.401 Reports submitted to the...

41 CFR 105-50.401 - Reports submitted to the Congress.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 41 Public Contracts and Property Management 3 2013-07-01 2013-07-01 false Reports submitted to the Congress. 105-50.401 Section 105-50.401 Public Contracts and Property Management Federal Property... TECHNICAL SERVICES TO STATE AND LOCAL UNITS OF GOVERNMENT 50.4-Reports § 105-50.401 Reports submitted to the...

41 CFR 105-50.401 - Reports submitted to the Congress.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 41 Public Contracts and Property Management 3 2014-01-01 2014-01-01 false Reports submitted to the Congress. 105-50.401 Section 105-50.401 Public Contracts and Property Management Federal Property... TECHNICAL SERVICES TO STATE AND LOCAL UNITS OF GOVERNMENT 50.4-Reports § 105-50.401 Reports submitted to the...

41 CFR 105-50.401 - Reports submitted to the Congress.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Reports submitted to the Congress. 105-50.401 Section 105-50.401 Public Contracts and Property Management Federal Property... TECHNICAL SERVICES TO STATE AND LOCAL UNITS OF GOVERNMENT 50.4-Reports § 105-50.401 Reports submitted to the...

41 CFR 105-50.401 - Reports submitted to the Congress.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false Reports submitted to the Congress. 105-50.401 Section 105-50.401 Public Contracts and Property Management Federal Property... TECHNICAL SERVICES TO STATE AND LOCAL UNITS OF GOVERNMENT 50.4-Reports § 105-50.401 Reports submitted to the...

Value engineering and cost effectiveness of various fiber reinforced polymer (FRP) repair systems : final report, June 2007.

DOT National Transportation Integrated Search

2007-06-01

This report is an extension to the final report for NCDOT project 2004-15 Value Engineering and Cost-Effectiveness of : Various Fiber Reinforced Polymers (FRP) Repair Systems, submitted in June 2005. In that report, seventeen 30-ft long : prest...

Mathematical model of depolarization mechanism of conducted vasoreactivity

NASA Astrophysics Data System (ADS)

Neganova, Anastasiia Y.; Stiukhina, Elena S.; Postnov, Dmitry E.

2015-03-01

We address the problem of conducted vasodilation, the phenomenon which is also known as functional hyperemia. Specifically, we test the mechanism of nondecremental propagation of electric signals along endothelial cell layer recently hypothesized by Figueroa et al. By means of functional modeling we focus on possible nonlinear mechanisms that can underlie such regenerative pulse transmission (RPT). Since endothelial cells (EC) are generally known as electrically inexcitable, the possible role of ECs in RPT mechanisms is not evident. By means of mathematical modeling we check the dynamical self-consistency of Figueroa's hypothesis, as well as estimate the possible contribution of specific ionic currents to the suggested RPT mechanism.

Department of Defense Congressional Action on FY 1984 Appropriation Request.

DTIC Science & Technology

1983-12-08

CONSTRUCTION (9,800) (9 800) 9 800) 147 FORT DEVENS MA 3,000 3,000 3 000 147 CHILD CARE FACILITY (3,000) (3.0001 3,000) 160 FORT MONMOUTH NJ 12,400 2,500 -12,400...Amended tion RAC Rpt. SAC Rpt. Con# Rpt Enacted Appropriation Title and item Budget PL98-94 No.98-427 No.98-292 No. 98-567 PL98-21? Request Floor Act...ICI-11-I) 5.100 5,100 -I , , 153 MULTI SIJDSCRIBER EQ (HTTB) 4,400 4,400 I 165 MOD IN SER EQ (INT SPT) 69,100 69,100 -17,100 I. 109 FT DEVENS

Current good manufacturing practices, quality control procedures, quality factors, notification requirements, and records and reports, for infant formula. Final rule.

PubMed

2014-06-10

The Food and Drug Administration (FDA or we) is issuing a final rule that adopts, with some modifications, the interim final rule (IFR) entitled "Current Good Manufacturing Practices, Quality Control Procedures, Quality Factors, Notification Requirements, and Records and Reports, for Infant Formula'' (February 10, 2014). This final rule affirms the IFR's changes to FDA's regulations and provides additional modifications and clarifications. The final rule also responds to certain comments submitted in response to the request for comments in the IFR.

20 CFR 416.802 - Type of evidence to be submitted.

Code of Federal Regulations, 2010 CFR

2010-04-01

... individual is required to submit evidence of date of birth as indicated in § 416.801, he shall submit a public record of birth or a religious record of birth or baptism established or recorded before his fifth... determination of the individual's date of birth provided such evidence is corroborated by other evidence or by...

30 CFR 285.642 - How do I submit my GAP?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How do I submit my GAP? 285.642 Section 285.642 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY... address listed in § 285.110(a). (b) If you have a limited lease, you may submit information on any project...

42 CFR 405.1018 - Submitting evidence before the ALJ hearing.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 2 2010-10-01 2010-10-01 false Submitting evidence before the ALJ hearing. 405... written evidence they wish to have considered at the hearing with the request for hearing (or within 10 calendar days of receiving the notice of hearing). (b) If a party submits written evidence later than 10...

42 CFR 405.1018 - Submitting evidence before the ALJ hearing.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 2 2011-10-01 2011-10-01 false Submitting evidence before the ALJ hearing. 405... written evidence they wish to have considered at the hearing with the request for hearing (or within 10 calendar days of receiving the notice of hearing). (b) If a party submits written evidence later than 10...

44 CFR 65.4 - Right to submit new technical data.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Right to submit new technical... IDENTIFICATION AND MAPPING OF SPECIAL HAZARD AREAS § 65.4 Right to submit new technical data. (a) A community has..., other than those initiatedby FEMA, must be made in writing by the Chief Executive Officer of the...

15 CFR 325.14 - Submitting reports.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Submitting reports. 325.14 Section 325.14 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT OF COMMERCE MISCELLANEOUS REGULATIONS EXPORT TRADE CERTIFICATES...

76 FR 48861 - Notice of Issuance of Final Outer Continental Shelf Air Permit for Anadarko Petroleum Corporation

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-09

... Continental Shelf Air Permit for Anadarko Petroleum Corporation AGENCY: Environmental Protection Agency (EPA... final Outer Continental Shelf (OCS) air permit for Anadarko Petroleum Corporation (Anadarko). The permit... Petroleum Corporation regarding the project. EPA carefully reviewed each of the comments submitted and...

47 CFR 36.612 - Updating information submitted to the National Exchange Carrier Association.

Code of Federal Regulations, 2013 CFR

2013-10-01

... update the information submitted to the National Exchange Carrier Association (NECA) on July 31st... non-rural telephone company must update the information submitted to NECA on July 31st pursuant to § 36.611 (h) according to the schedule. (1) Submit data covering the last nine months of the previous...

47 CFR 36.612 - Updating information submitted to the National Exchange Carrier Association.

Code of Federal Regulations, 2012 CFR

2012-10-01

... update the information submitted to the National Exchange Carrier Association (NECA) on July 31st... non-rural telephone company must update the information submitted to NECA on July 31st pursuant to § 36.611 (h) according to the schedule. (1) Submit data covering the last nine months of the previous...

77 FR 24405 - Direct Final Approval of Hospital/Medical/Infectious Waste Incinerators State Plan for Designated...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-24

... Incinerators'' (HMIWI). The Indiana Department of Environmental Management (IDEM) submitted the revised State... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 62 [EPA-R05-OAR-2012-0086; FRL-9663-2] Direct Final Approval of Hospital/Medical/Infectious Waste Incinerators State Plan for Designated Facilities and...

Final report on CCQM-K125: elements in infant formula

NASA Astrophysics Data System (ADS)

Merrick, J.; Saxby, D.; Dutra, E. S.; Sena, R. C.; Araújo, T. O.; Almeida, M. D.; Yang, L.; Pihillagawa, I. G.; Mester, Z.; Sandoval, S.; Wei, C.; Castillo, M. E. D.; Oster, C.; Fisicaro, P.; Rienitz, O.; Pape, C.; Schulz, U.; Jährling, R.; Görlitz, V.; Lampi, E.; Kakoulides, E.; Sin, D. W. M.; Yip, Y. C.; Tsoi, Y. T.; Zhu, Y.; Okumu, T. O.; Yim, Y. H.; Heo, S. W.; Han, M.; Lim, Y.; Osuna, M. A.; Regalado, L.; Uribe, C.; Buzoianu, M. M.; Duta, S.; Konopelko, L.; Krylov, A.; Shin, R.; Linsky, M.; Botha, A.; Magnusson, B.; Haraldsson, C.; Thiengmanee, U.; Klich, H.; Can, S. Z.; Coskun, F. G.; Tunc, M.; Entwisle, J.; O'Reilly, J.; Hill, S.; Goenaga-Infante, H.; Winchester, M.; Rabb, S. A.; Pérez, R.

2017-01-01

CCQM-K125 was organized by the Inorganic Analysis Working Group (IAWG) of CCQM to assess and document the capabilities of the national metrology institutes (NMIs) or the designated institutes (DIs) to measure the mass fractions of trace elements (K, Cu and I) in infant formula. Government Laboratory, Hong Kong SAR (GLHK) acted as the coordinating laboratory. In CCQM-K125, 25 institutes submitted the results for potassium, 24 institutes submitted the results for copper and 8 institutes submitted the results for iodine. For examination of potassium and copper, most of the participants used microwave-assisted acid digestion methods for sample dissolution. A variety of instrumental techniques including inductively coupled plasma mass spectrometry (ICP-MS), isotope dilution inductively coupled plasma mass spectrometry (ID-ICP-MS), inductively coupled plasma optical emission spectrometry (ICP-OES), atomic absorption spectrometry (AAS), flame atomic emission spectrometry (FAES) and microwave plasma atomic emission spectroscopy (MP-AES) were employed by the participants for determination. For analysis of iodine, most of the participants used alkaline extraction methods for sample preparation. ICP-MS and ID-ICP-MS were used by the participants for the determination. Generally, the participants' results of CCQM-K125 were found consistent for all measurands according to their equivalence statements. Except with some extreme values, most of the participants obtained the values of di/U(di) within +/- 1 for the measurands. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

24 CFR 245.315 - Materials to be submitted to HUD.

Code of Federal Regulations, 2010 CFR

2010-04-01

... local HUD office: (a) Documents to be submitted under profit and loss approach: (1) A copy of the notice... Increase in Maximum Permissible Rents § 245.315 Materials to be submitted to HUD. When the notice referred to in § 245.310 is served on the tenants, the mortgagor must send to the local HUD office copies of...

24 CFR 245.315 - Materials to be submitted to HUD.

Code of Federal Regulations, 2011 CFR

2011-04-01

... local HUD office: (a) Documents to be submitted under profit and loss approach: (1) A copy of the notice... Increase in Maximum Permissible Rents § 245.315 Materials to be submitted to HUD. When the notice referred to in § 245.310 is served on the tenants, the mortgagor must send to the local HUD office copies of...

30 CFR 585.622 - How do I submit my COP?

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 2 2012-07-01 2012-07-01 false How do I submit my COP? 585.622 Section 585.622 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY... § 585.110(a). (b) You may submit information and a request for any project easement as part of your...

30 CFR 585.622 - How do I submit my COP?

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 2 2014-07-01 2014-07-01 false How do I submit my COP? 585.622 Section 585.622 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY... § 585.110(a). (b) You may submit information and a request for any project easement as part of your...

30 CFR 585.622 - How do I submit my COP?

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 2 2013-07-01 2013-07-01 false How do I submit my COP? 585.622 Section 585.622 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY... § 585.110(a). (b) You may submit information and a request for any project easement as part of your...

Soluble β-(1,3)-glucans enhance LPS-induced response in the monocyte activation test, but inhibit LPS-mediated febrile response in rabbits: Implications for pyrogenicity tests.

PubMed

Pardo-Ruiz, Zenia; Menéndez-Sardiñas, Dalia E; Pacios-Michelena, Anabel; Gabilondo-Ramírez, Tatiana; Montero-Alejo, Vivian; Perdomo-Morales, Rolando

2016-01-01

In the present study, we aimed to determine the influence of β-(1,3)-d-glucans on the LPS-induced pro-inflammatory cytokine response in the Monocyte Activation Test (MAT) for pyrogens, and on the LPS-induced febrile response in the Rabbit Pyrogen Test (RPT), thus evaluating the resulting effect in the outcome of each test. It was found that β-(1,3)-d-glucans elicited the production of pro-inflammatory cytokines IL-1β, IL-6 and TNF-α, also known as endogenous pyrogens, but not enough to classify them as pyrogenic according to MAT. The same β-(1,3)-d-glucans samples were non-pyrogenic by RPT. However, β-(1,3)-d-glucans significantly enhanced the LPS-induced pro-inflammatory cytokines response in MAT, insomuch that samples containing non-pyrogenic concentrations of LPS become pyrogenic. On the other hand, β-(1,3)-d-glucans had no effect on sub-pyrogenic LPS doses in the RPT, but surprisingly, inhibited the LPS-induced febrile response of pyrogenic LPS concentrations. Thus, while β-(1,3)-d-glucans could mask the LPS pyrogenic activity in the RPT, they exerted an overstimulation of pro-inflammatory cytokines in the MAT. Hence, MAT provides higher safety since it evidences an unwanted biological response, which is not completely controlled and is overlooked by the RPT. Copyright © 2015 Elsevier B.V. All rights reserved.

Topological characterization of antireflective and hydrophobic rough surfaces: are random process theory and fractal modeling applicable?

NASA Astrophysics Data System (ADS)

Borri, Claudia; Paggi, Marco

2015-02-01

The random process theory (RPT) has been widely applied to predict the joint probability distribution functions (PDFs) of asperity heights and curvatures of rough surfaces. A check of the predictions of RPT against the actual statistics of numerically generated random fractal surfaces and of real rough surfaces has been only partially undertaken. The present experimental and numerical study provides a deep critical comparison on this matter, providing some insight into the capabilities and limitations in applying RPT and fractal modeling to antireflective and hydrophobic rough surfaces, two important types of textured surfaces. A multi-resolution experimental campaign using a confocal profilometer with different lenses is carried out and a comprehensive software for the statistical description of rough surfaces is developed. It is found that the topology of the analyzed textured surfaces cannot be fully described according to RPT and fractal modeling. The following complexities emerge: (i) the presence of cut-offs or bi-fractality in the power-law power-spectral density (PSD) functions; (ii) a more pronounced shift of the PSD by changing resolution as compared to what was expected from fractal modeling; (iii) inaccuracy of the RPT in describing the joint PDFs of asperity heights and curvatures of textured surfaces; (iv) lack of resolution-invariance of joint PDFs of textured surfaces in case of special surface treatments, not accounted for by fractal modeling.

30 CFR 250.287 - For what development projects must I submit a DWOP?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false For what development projects must I submit a... Operations Plans (dwop) § 250.287 For what development projects must I submit a DWOP? You must submit a DWOP for each development project in which you will use non-conventional production or completion...

47 CFR 36.612 - Updating information submitted to the National Exchange Carrier Association.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., may update the information submitted to the National Exchange Carrier Association (NECA) on July 31st... must update the information submitted to NECA on July 31st pursuant to § 36.611(h) according to the schedule. Every non-rural telephone company must update the information submitted to NECA on July 31st...

47 CFR 36.612 - Updating information submitted to the National Exchange Carrier Association.

Code of Federal Regulations, 2011 CFR

2011-10-01

..., may update the information submitted to the National Exchange Carrier Association (NECA) on July 31st... must update the information submitted to NECA on July 31st pursuant to § 36.611(h) according to the schedule. Every non-rural telephone company must update the information submitted to NECA on July 31st...

30 CFR 250.287 - For what development projects must I submit a DWOP?

Code of Federal Regulations, 2014 CFR

2014-07-01

... and Information Deepwater Operations Plan (dwop) § 250.287 For what development projects must I submit a DWOP? You must submit a DWOP for each development project in which you will use non-conventional... 30 Mineral Resources 2 2014-07-01 2014-07-01 false For what development projects must I submit a...

30 CFR 250.287 - For what development projects must I submit a DWOP?

Code of Federal Regulations, 2013 CFR

2013-07-01

... and Information Deepwater Operations Plan (dwop) § 250.287 For what development projects must I submit a DWOP? You must submit a DWOP for each development project in which you will use non-conventional... 30 Mineral Resources 2 2013-07-01 2013-07-01 false For what development projects must I submit a...

30 CFR 250.287 - For what development projects must I submit a DWOP?

Code of Federal Regulations, 2012 CFR

2012-07-01

... and Information Deepwater Operations Plan (dwop) § 250.287 For what development projects must I submit a DWOP? You must submit a DWOP for each development project in which you will use non-conventional... 30 Mineral Resources 2 2012-07-01 2012-07-01 false For what development projects must I submit a...

28 CFR 54.225 - Educational institutions eligible to submit transition plans.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Educational institutions eligible to submit transition plans. 54.225 Section 54.225 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED... Coverage § 54.225 Educational institutions eligible to submit transition plans. (a) Application. This...

47 CFR 54.1306 - Updating Information Submitted to the National Exchange Carrier Association.

Code of Federal Regulations, 2014 CFR

2014-10-01

... incumbent local exchange carrier subject to § 54.1301(a) may update the information submitted to the... on a rolling year basis according to the schedule. (1) Submit data covering the last nine months of... September 30th of the existing year; (2) Submit data covering the last six months of the previous calendar...

30 CFR 250.287 - For what development projects must I submit a DWOP?

Code of Federal Regulations, 2011 CFR

2011-07-01

... SHELF Plans and Information Deepwater Operations Plans (dwop) § 250.287 For what development projects must I submit a DWOP? You must submit a DWOP for each development project in which you will use non... 30 Mineral Resources 2 2011-07-01 2011-07-01 false For what development projects must I submit a...

10 CFR 1042.225 - Educational institutions eligible to submit transition plans.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Educational institutions eligible to submit transition plans. 1042.225 Section 1042.225 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NONDISCRIMINATION ON... § 1042.225 Educational institutions eligible to submit transition plans. (a) Application. This section...

10 CFR 1042.225 - Educational institutions eligible to submit transition plans.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Educational institutions eligible to submit transition plans. 1042.225 Section 1042.225 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NONDISCRIMINATION ON... § 1042.225 Educational institutions eligible to submit transition plans. (a) Application. This section...

10 CFR 1042.225 - Educational institutions eligible to submit transition plans.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Educational institutions eligible to submit transition plans. 1042.225 Section 1042.225 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NONDISCRIMINATION ON... § 1042.225 Educational institutions eligible to submit transition plans. (a) Application. This section...

10 CFR 1042.225 - Educational institutions eligible to submit transition plans.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Educational institutions eligible to submit transition plans. 1042.225 Section 1042.225 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NONDISCRIMINATION ON... § 1042.225 Educational institutions eligible to submit transition plans. (a) Application. This section...

10 CFR 1042.225 - Educational institutions eligible to submit transition plans.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Educational institutions eligible to submit transition plans. 1042.225 Section 1042.225 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NONDISCRIMINATION ON... § 1042.225 Educational institutions eligible to submit transition plans. (a) Application. This section...

20 CFR 405.333 - Submitting documents.

Code of Federal Regulations, 2010 CFR

2010-04-01

... digits of the claimant's social security number. All such documents must be clear and legible to the... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Submitting documents. 405.333 Section 405.333 Employees' Benefits SOCIAL SECURITY ADMINISTRATION ADMINISTRATIVE REVIEW PROCESS FOR ADJUDICATING INITIAL...

49 CFR 655.49 - Refusal to submit to a drug or alcohol test.

Code of Federal Regulations, 2013 CFR

2013-10-01

... IN TRANSIT OPERATIONS Types of Testing § 655.49 Refusal to submit to a drug or alcohol test. (a) Each employer shall require a covered employee to submit to a post-accident drug and alcohol test required under... 49 Transportation 7 2013-10-01 2013-10-01 false Refusal to submit to a drug or alcohol test. 655...

49 CFR 655.49 - Refusal to submit to a drug or alcohol test.

Code of Federal Regulations, 2011 CFR

2011-10-01

... IN TRANSIT OPERATIONS Types of Testing § 655.49 Refusal to submit to a drug or alcohol test. (a) Each employer shall require a covered employee to submit to a post-accident drug and alcohol test required under... 49 Transportation 7 2011-10-01 2011-10-01 false Refusal to submit to a drug or alcohol test. 655...

49 CFR 655.49 - Refusal to submit to a drug or alcohol test.

Code of Federal Regulations, 2014 CFR

2014-10-01

... IN TRANSIT OPERATIONS Types of Testing § 655.49 Refusal to submit to a drug or alcohol test. (a) Each employer shall require a covered employee to submit to a post-accident drug and alcohol test required under... 49 Transportation 7 2014-10-01 2014-10-01 false Refusal to submit to a drug or alcohol test. 655...

49 CFR 655.49 - Refusal to submit to a drug or alcohol test.

Code of Federal Regulations, 2012 CFR

2012-10-01

... IN TRANSIT OPERATIONS Types of Testing § 655.49 Refusal to submit to a drug or alcohol test. (a) Each employer shall require a covered employee to submit to a post-accident drug and alcohol test required under... 49 Transportation 7 2012-10-01 2012-10-01 false Refusal to submit to a drug or alcohol test. 655...

49 CFR 655.49 - Refusal to submit to a drug or alcohol test.

Code of Federal Regulations, 2010 CFR

2010-10-01

... IN TRANSIT OPERATIONS Types of Testing § 655.49 Refusal to submit to a drug or alcohol test. (a) Each employer shall require a covered employee to submit to a post-accident drug and alcohol test required under... 49 Transportation 7 2010-10-01 2010-10-01 false Refusal to submit to a drug or alcohol test. 655...

30 CFR 250.288 - When and how must I submit the Conceptual Plan?

Code of Federal Regulations, 2010 CFR

2010-07-01

... OFFSHORE OIL AND GAS AND SULPHUR OPERATIONS IN THE OUTER CONTINENTAL SHELF Plans and Information Deepwater Operations Plans (dwop) § 250.288 When and how must I submit the Conceptual Plan? You must submit four copies... 30 Mineral Resources 2 2010-07-01 2010-07-01 false When and how must I submit the Conceptual Plan...

76 FR 16534 - Hazardous Waste Management System Identification and Listing of Hazardous Waste; Final Exclusion

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-24

... issued exclusion from taking effect in the State until the State approves the exclusion through a..., this final rule does not have federalism implications. It will not have substantial direct effects on... provides that before a rule may take effect, the agency promulgating the rule must submit a rule report...

Preparing, Submitting, and Tracking a Grant Application

Cancer.gov

Information compiled by NCI's Epidemiology and Genomics Research Program to help investigators learn more about NIH and NCI information and policies related to writing and submitting new, resubmission, late, and renewal grant applications.

10 CFR 5.225 - Educational institutions eligible to submit transition plans.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 1 2013-01-01 2013-01-01 false Educational institutions eligible to submit transition plans. 5.225 Section 5.225 Energy NUCLEAR REGULATORY COMMISSION NONDISCRIMINATION ON THE BASIS OF SEX IN... institutions eligible to submit transition plans. (a) Application. This section applies to each educational...

10 CFR 5.225 - Educational institutions eligible to submit transition plans.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 1 2014-01-01 2014-01-01 false Educational institutions eligible to submit transition plans. 5.225 Section 5.225 Energy NUCLEAR REGULATORY COMMISSION NONDISCRIMINATION ON THE BASIS OF SEX IN... institutions eligible to submit transition plans. (a) Application. This section applies to each educational...

10 CFR 5.225 - Educational institutions eligible to submit transition plans.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 1 2011-01-01 2011-01-01 false Educational institutions eligible to submit transition plans. 5.225 Section 5.225 Energy NUCLEAR REGULATORY COMMISSION NONDISCRIMINATION ON THE BASIS OF SEX IN... institutions eligible to submit transition plans. (a) Application. This section applies to each educational...

10 CFR 5.225 - Educational institutions eligible to submit transition plans.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 1 2012-01-01 2012-01-01 false Educational institutions eligible to submit transition plans. 5.225 Section 5.225 Energy NUCLEAR REGULATORY COMMISSION NONDISCRIMINATION ON THE BASIS OF SEX IN... institutions eligible to submit transition plans. (a) Application. This section applies to each educational...

10 CFR 5.225 - Educational institutions eligible to submit transition plans.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 1 2010-01-01 2010-01-01 false Educational institutions eligible to submit transition plans. 5.225 Section 5.225 Energy NUCLEAR REGULATORY COMMISSION NONDISCRIMINATION ON THE BASIS OF SEX IN... institutions eligible to submit transition plans. (a) Application. This section applies to each educational...

40 CFR 125.124 - Information required to be submitted by applicant.

Code of Federal Regulations, 2013 CFR

2013-07-01

... information: (a) An analysis of the chemical constituents of any discharge; (b) Appropriate bioassays... 40 Protection of Environment 23 2013-07-01 2013-07-01 false Information required to be submitted... Ocean Discharge Criteria § 125.124 Information required to be submitted by applicant. The applicant is...

25 CFR 533.2 - Time for submitting management contracts and amendments.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Time for submitting management contracts and amendments. 533.2 Section 533.2 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR MANAGEMENT CONTRACT PROVISIONS APPROVAL OF MANAGEMENT CONTRACTS § 533.2 Time for submitting management contracts and...

Structural Defects in the Regulatory Particle-Core Particle Interface of the Proteasome Induce a Novel Proteasome Stress Response*

PubMed Central

Park, Soyeon; Kim, Woong; Tian, Geng; Gygi, Steven P.; Finley, Daniel

2011-01-01

Proteasomes consist of a 19-subunit regulatory particle (RP) and 28-subunit core particle (CP), an α7β7β7α7 structure. The RP recognizes substrates and translocates them into the CP for degradation. At the RP-CP interface, a heterohexameric Rpt ring joins to a heteroheptameric CP α ring. Rpt C termini insert individually into the α ring pockets to form a salt bridge with a pocket lysine residue. We report that substitutions of α pocket lysine residues produce an unexpected block to CP assembly, arising from a late stage defect in β ring assembly. Substitutions α5K66A and α6K62A resulted in abundant incorporation of immature CP β subunits, associated with a complete β ring, into proteasome holoenzymes. Incorporation of immature CP into the proteasome depended on a proteasome-associated protein, Ecm29. Using ump1 mutants, we identified Ecm29 as a potent negative regulator of RP assembly and confirmed our previous findings that proper RP assembly requires the CP. Ecm29 was enriched on proteasomes of pocket lysine mutants, as well as those of rpt4-Δ1 and rpt6-Δ1 mutants, in which the C-terminal residue, thought to contact the pocket lysine, is deleted. In both rpt6-Δ1 and α6K62A proteasomes, Ecm29 suppressed opening of the CP substrate translocation channel, which is gated through interactions between Rpt C termini and the α pockets. The ubiquitin ligase Hul5 was recruited to these proteasomes together with Ecm29. Proteasome remodeling through the addition of Ecm29 and Hul5 suggests a new layer of the proteasome stress response and may be a common response to structurally aberrant proteasomes or deficient proteasome function. PMID:21878652

7 CFR 75.37 - Submitted samples.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 3 2014-01-01 2014-01-01 false Submitted samples. 75.37 Section 75.37 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE...

7 CFR 75.37 - Submitted samples.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 3 2013-01-01 2013-01-01 false Submitted samples. 75.37 Section 75.37 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE...

7 CFR 75.37 - Submitted samples.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 3 2012-01-01 2012-01-01 false Submitted samples. 75.37 Section 75.37 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE...

30 CFR 210.104 - Must I submit these production reports electronically?

Code of Federal Regulations, 2010 CFR

2010-07-01

... MINERALS REVENUE MANAGEMENT FORMS AND REPORTS Production Reports-Oil and Gas § 210.104 Must I submit these... Production Reporter Handbook for the most current reporting options, instructions, and security measures. The... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Must I submit these production reports...

40 CFR 152.93 - Citation of a previously submitted valid study.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Data Submitters' Rights § 152.93 Citation of a previously submitted valid study. An applicant may demonstrate compliance for a data requirement by citing a valid study previously submitted to the Agency. The... the original data submitter, the applicant may cite the study only in accordance with paragraphs (b...

40 CFR 55.4 - Requirements to submit a notice of intent.

Code of Federal Regulations, 2011 CFR

2011-07-01

... intent. 55.4 Section 55.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) OUTER CONTINENTAL SHELF AIR REGULATIONS § 55.4 Requirements to submit a notice of... Regional Office, and at the same time shall submit copies of the NOI to the air pollution control agencies...

40 CFR 55.4 - Requirements to submit a notice of intent.

Code of Federal Regulations, 2010 CFR

2010-07-01

... intent. 55.4 Section 55.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) OUTER CONTINENTAL SHELF AIR REGULATIONS § 55.4 Requirements to submit a notice of... Regional Office, and at the same time shall submit copies of the NOI to the air pollution control agencies...

40 CFR 55.4 - Requirements to submit a notice of intent.

Code of Federal Regulations, 2014 CFR

2014-07-01

... intent. 55.4 Section 55.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) OUTER CONTINENTAL SHELF AIR REGULATIONS § 55.4 Requirements to submit a notice of... Regional Office, and at the same time shall submit copies of the NOI to the air pollution control agencies...

40 CFR 55.4 - Requirements to submit a notice of intent.

Code of Federal Regulations, 2012 CFR

2012-07-01

... intent. 55.4 Section 55.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) OUTER CONTINENTAL SHELF AIR REGULATIONS § 55.4 Requirements to submit a notice of... Regional Office, and at the same time shall submit copies of the NOI to the air pollution control agencies...

40 CFR 55.4 - Requirements to submit a notice of intent.

Code of Federal Regulations, 2013 CFR

2013-07-01

... intent. 55.4 Section 55.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) OUTER CONTINENTAL SHELF AIR REGULATIONS § 55.4 Requirements to submit a notice of... Regional Office, and at the same time shall submit copies of the NOI to the air pollution control agencies...

40 CFR 125.124 - Information required to be submitted by applicant.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 22 2014-07-01 2013-07-01 true Information required to be submitted by... Discharge Criteria § 125.124 Information required to be submitted by applicant. The applicant is responsible for providing information which the director may request to make the determination required by this...

45 CFR 154.230 - Submission and posting of Final Justifications for unreasonable rate increases.

Code of Federal Regulations, 2011 CFR

2011-10-01

... information available to the public on its Web site for at least three years. (d) CMS will post all Final Justifications on the CMS Web site. This information will remain available to the public on the CMS Web site for... submitted in the Preliminary Justification supporting the rate increase; and (2) Prominently post on its Web...

Preparation and quantification of radioactive particles for tracking hydrodynamic behavior in multiphase reactors.

PubMed

Yunos, Mohd Amirul Syafiq Mohd; Hussain, Siti Aslina; Yusoff, Hamdan Mohamed; Abdullah, Jaafar

2014-09-01

Radioactive particle tracking (RPT) has emerged as a promising and versatile technique that can provide rich information about a variety of multiphase flow systems. However, RPT is not an off-the-shelf technique, and thus, users must customize RPT for their applications. This paper presents a simple procedure for preparing radioactive tracer particles created via irradiation with neutrons from the TRIGA Mark II research reactor. The present study focuses on the performance evaluation of encapsulated gold and scandium particles for applications as individual radioactive tracer particles using qualitative and quantitative neutron activation analysis (NAA) and an X-ray microcomputed tomography (X-ray Micro-CT) scanner installed at the Malaysian Nuclear Agency. Copyright © 2014 Elsevier Ltd. All rights reserved.

78 FR 34918 - Direct Final Approval of Sewage Sludge Incinerators State Plan for Designated Facilities and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-11

... Environmental Management (IDEM) submitted the State Plan on February 27, 2013. The State Plan is consistent with... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 62 [EPA-R05-OAR-2013-0372; FRL-9821-1] Direct Final Approval of Sewage Sludge Incinerators State Plan for Designated Facilities and Pollutants; Indiana AGENCY...

77 FR 32022 - Direct Final Negative Declaration and Withdrawal of Large Municipal Waste Combustors State Plan...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-31

... Negative Declaration and Withdrawal of Large Municipal Waste Combustors State Plan for Designated.... SUMMARY: EPA is taking direct final action to approve Illinois' negative declaration and request for EPA..., the state may submit a letter of certification to that effect, or a negative declaration, in lieu of a...

21 CFR 20.114 - Data and information submitted pursuant to cooperative quality assurance agreements.

Code of Federal Regulations, 2014 CFR

2014-04-01

... Records § 20.114 Data and information submitted pursuant to cooperative quality assurance agreements. Data and information submitted to the Food and Drug Administration pursuant to a cooperative quality... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Data and information submitted pursuant to...

21 CFR 20.114 - Data and information submitted pursuant to cooperative quality assurance agreements.

Code of Federal Regulations, 2011 CFR

2011-04-01

... Records § 20.114 Data and information submitted pursuant to cooperative quality assurance agreements. Data and information submitted to the Food and Drug Administration pursuant to a cooperative quality... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Data and information submitted pursuant to...

21 CFR 20.114 - Data and information submitted pursuant to cooperative quality assurance agreements.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Records § 20.114 Data and information submitted pursuant to cooperative quality assurance agreements. Data and information submitted to the Food and Drug Administration pursuant to a cooperative quality... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Data and information submitted pursuant to...

21 CFR 20.114 - Data and information submitted pursuant to cooperative quality assurance agreements.

Code of Federal Regulations, 2013 CFR

2013-04-01

... Records § 20.114 Data and information submitted pursuant to cooperative quality assurance agreements. Data and information submitted to the Food and Drug Administration pursuant to a cooperative quality... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Data and information submitted pursuant to...

31 CFR 103.81 - Submitting requests.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Submitting requests. 103.81 Section 103.81 Money and Finance: Treasury Regulations Relating to Money and Finance FINANCIAL RECORDKEEPING... which the request is made. (b) A request filed by a corporation shall be signed by a corporate officer...

Course Factors That Motivate Students to Submit End-of-Course Evaluations

ERIC Educational Resources Information Center

Jaquett, Caroline M.; VanMaaren, Victoria G.; Williams, Robert L.

2017-01-01

We surveyed students (N = 152) in several sections of an undergraduate educational psychology course to determine what course factors would most motivate them to submit course evaluations. The survey directed students to choose among several pairs of course characteristics as to their relative impact on their decision to submit a course…

34 CFR 75.125 - Submit a separate application to each program.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 34 Education 1 2014-07-01 2014-07-01 false Submit a separate application to each program. 75.125 Section 75.125 Education Office of the Secretary, Department of Education DIRECT GRANT PROGRAMS How To Apply for a Grant Separate Applications-Alternative Programs § 75.125 Submit a separate application to...

25 CFR 559.7 - May a tribe submit documents required by this part electronically?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false May a tribe submit documents required by this part... NOTIFICATIONS AND SUBMISSIONS § 559.7 May a tribe submit documents required by this part electronically? Yes. Tribes wishing to submit documents electronically should contact the Commission for guidance on...

25 CFR 559.7 - May a tribe submit documents required by this part electronically?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false May a tribe submit documents required by this part... NOTIFICATIONS AND SUBMISSIONS § 559.7 May a tribe submit documents required by this part electronically? Yes. Tribes wishing to submit documents electronically should contact the Commission for guidance on...

40 CFR 60.2795 - In what form can I submit my reports?

Code of Federal Regulations, 2012 CFR

2012-07-01

... (CDX) by using the Electronic Reporting Tool (ERT) (see http://www.epa.gov/ttn/chief/ert/ert_tool.html). ... Reporting § 60.2795 In what form can I submit my reports? Submit initial, annual, and deviation reports...

20 CFR 30.701 - How are medical bills to be submitted?

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 1 2012-04-01 2012-04-01 false How are medical bills to be submitted? 30.701... EMPLOYEES OCCUPATIONAL ILLNESS COMPENSATION PROGRAM ACT OF 2000, AS AMENDED Information for Medical Providers Medical Records and Bills § 30.701 How are medical bills to be submitted? (a) All charges for...

20 CFR 30.701 - How are medical bills to be submitted?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 1 2014-04-01 2012-04-01 true How are medical bills to be submitted? 30.701... EMPLOYEES OCCUPATIONAL ILLNESS COMPENSATION PROGRAM ACT OF 2000, AS AMENDED Information for Medical Providers Medical Records and Bills § 30.701 How are medical bills to be submitted? (a) All charges for...

20 CFR 10.801 - How are medical bills to be submitted?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 20 Employees' Benefits 1 2013-04-01 2012-04-01 true How are medical bills to be submitted? 10.801... AMENDED Information for Medical Providers Medical Records and Bills § 10.801 How are medical bills to be submitted? (a) All charges for medical and surgical treatment, appliances or supplies furnished to injured...

20 CFR 30.701 - How are medical bills to be submitted?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 1 2011-04-01 2011-04-01 false How are medical bills to be submitted? 30.701... EMPLOYEES OCCUPATIONAL ILLNESS COMPENSATION PROGRAM ACT OF 2000, AS AMENDED Information for Medical Providers Medical Records and Bills § 30.701 How are medical bills to be submitted? (a) All charges for...

20 CFR 10.801 - How are medical bills to be submitted?

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 1 2012-04-01 2012-04-01 false How are medical bills to be submitted? 10.801... AMENDED Information for Medical Providers Medical Records and Bills § 10.801 How are medical bills to be submitted? (a) All charges for medical and surgical treatment, appliances or supplies furnished to injured...

20 CFR 30.701 - How are medical bills to be submitted?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 20 Employees' Benefits 1 2013-04-01 2012-04-01 true How are medical bills to be submitted? 30.701... EMPLOYEES OCCUPATIONAL ILLNESS COMPENSATION PROGRAM ACT OF 2000, AS AMENDED Information for Medical Providers Medical Records and Bills § 30.701 How are medical bills to be submitted? (a) All charges for...

20 CFR 10.801 - How are medical bills to be submitted?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 1 2014-04-01 2012-04-01 true How are medical bills to be submitted? 10.801... AMENDED Information for Medical Providers Medical Records and Bills § 10.801 How are medical bills to be submitted? (a) All charges for medical and surgical treatment, appliances or supplies furnished to injured...

20 CFR 10.801 - How are medical bills to be submitted?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 1 2011-04-01 2011-04-01 false How are medical bills to be submitted? 10.801... AMENDED Information for Medical Providers Medical Records and Bills § 10.801 How are medical bills to be submitted? (a) All charges for medical and surgical treatment, appliances or supplies furnished to injured...

40 CFR 63.9535 - What notifications must I submit and when?

Code of Federal Regulations, 2010 CFR

2010-07-01

...(b)(2), if you start up your affected source before October 18, 2002, you must submit your initial... start up your new affected source on or after October 18, 2002, you must submit your initial... status before the close of business on the 30th calendar day following the completion of the initial...

7 CFR 3406.22 - When and where to submit a proposal.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 15 2011-01-01 2011-01-01 false When and where to submit a proposal. 3406.22 Section... AND AGRICULTURE 1890 INSTITUTION CAPACITY BUILDING GRANTS PROGRAM Submission of a Teaching or Research Proposal § 3406.22 When and where to submit a proposal. The program announcement will provide the deadline...

7 CFR 3406.22 - When and where to submit a proposal.

Code of Federal Regulations, 2010 CFR

2010-01-01

... PROGRAM Submission of a Teaching or Research Proposal § 3406.22 When and where to submit a proposal. The... 7 Agriculture 15 2010-01-01 2010-01-01 false When and where to submit a proposal. 3406.22 Section 3406.22 Agriculture Regulations of the Department of Agriculture (Continued) COOPERATIVE STATE RESEARCH...

20 CFR 10.801 - How are medical bills to be submitted?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false How are medical bills to be submitted? 10.801... AMENDED Information for Medical Providers Medical Records and Bills § 10.801 How are medical bills to be submitted? (a) All charges for medical and surgical treatment, appliances or supplies furnished to injured...

20 CFR 30.701 - How are medical bills to be submitted?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false How are medical bills to be submitted? 30.701... EMPLOYEES OCCUPATIONAL ILLNESS COMPENSATION PROGRAM ACT OF 2000, AS AMENDED Information for Medical Providers Medical Records and Bills § 30.701 How are medical bills to be submitted? (a) All charges for...

20 CFR 220.48 - If the claimant fails to submit medical or other evidence.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 20 Employees' Benefits 1 2013-04-01 2012-04-01 true If the claimant fails to submit medical or other evidence. 220.48 Section 220.48 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER... fails to submit medical or other evidence. The Board may request a claimant to submit medical or other...

20 CFR 220.48 - If the claimant fails to submit medical or other evidence.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false If the claimant fails to submit medical or other evidence. 220.48 Section 220.48 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER... fails to submit medical or other evidence. The Board may request a claimant to submit medical or other...

20 CFR 220.48 - If the claimant fails to submit medical or other evidence.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 1 2011-04-01 2011-04-01 false If the claimant fails to submit medical or other evidence. 220.48 Section 220.48 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER... fails to submit medical or other evidence. The Board may request a claimant to submit medical or other...

20 CFR 220.48 - If the claimant fails to submit medical or other evidence.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 1 2014-04-01 2012-04-01 true If the claimant fails to submit medical or other evidence. 220.48 Section 220.48 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER... fails to submit medical or other evidence. The Board may request a claimant to submit medical or other...

20 CFR 220.48 - If the claimant fails to submit medical or other evidence.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 1 2012-04-01 2012-04-01 false If the claimant fails to submit medical or other evidence. 220.48 Section 220.48 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER... fails to submit medical or other evidence. The Board may request a claimant to submit medical or other...

25 CFR 514.15 - May tribes submit fingerprint cards to the NIGC for processing?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false May tribes submit fingerprint cards to the NIGC for... GENERAL PROVISIONS FEES § 514.15 May tribes submit fingerprint cards to the NIGC for processing? Tribes may submit fingerprint cards to the Commission for processing by the Federal Bureau of Investigation...

25 CFR 514.15 - May tribes submit fingerprint cards to the NIGC for processing?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false May tribes submit fingerprint cards to the NIGC for... GENERAL PROVISIONS FEES § 514.15 May tribes submit fingerprint cards to the NIGC for processing? Tribes may submit fingerprint cards to the Commission for processing by the Federal Bureau of Investigation...

78 FR 54218 - Endangered and Threatened Wildlife and Plants; 6-Month Extension of Final Determination for the...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-03

... submitted comments or information on the proposed rule during the two previously open comment periods...-Month Extension of Final Determination for the Proposed Listing and Designation of Critical Habitat for... rules; reopening of comment period. SUMMARY: We, the U.S. Fish and Wildlife Service (Service), announce...

Gene-for-gene relationship in the host-pathogen system Malus × robusta 5-Erwinia amylovora.

PubMed

Vogt, Isabelle; Wöhner, Thomas; Richter, Klaus; Flachowsky, Henryk; Sundin, George W; Wensing, Annette; Savory, Elizabeth A; Geider, Klaus; Day, Brad; Hanke, Magda-Viola; Peil, Andreas

2013-03-01

Fire blight is a destructive bacterial disease caused by Erwinia amylovora affecting plants in the family Rosaceae, including apple. Host resistance to fire blight is present mainly in accessions of Malus spp. and is thought to be quantitative in this pathosystem. In this study we analyzed the importance of the E. amylovora effector avrRpt2(EA) , a homolog of Pseudomonas syringae avrRpt2, for resistance of Malus × robusta 5 (Mr5). The deletion mutant E. amylovora Ea1189ΔavrRpt2(EA) was able to overcome the fire blight resistance of Mr5. One single nucleotide polymorphism (SNP), resulting in an exchange of cysteine to serine in the encoded protein, was detected in avrRpt2(EA) of several Erwinia strains differing in virulence to Mr5. E. amylovora strains encoding serine (S-allele) were able to overcome resistance of Mr5, whereas strains encoding cysteine (C-allele) were not. Allele specificity was also observed in a coexpression assay with Arabidopsis thaliana RIN4 in Nicotiana benthamiana. A homolog of RIN4 has been detected and isolated in Mr5. These results suggest a system similar to the interaction of RPS2 from A. thaliana and AvrRpt2 from P. syringae with RIN4 as guard. Our data are suggestive of a gene-for-gene relationship for the host-pathogen system Mr5 and E. amylovora. No claim to original US government works. New Phytologist © 2013 New Phytologist Trust.

Medicare program; prohibition of midyear benefit enhancements for Medicare Advantage organizations. Final rule.

PubMed

2008-07-28

This final rule prohibits Medicare Advantage (MA) organizations, including organizations offering MA plans to employer and union group health plan sponsors, from making midyear changes to nonprescription drug benefits, premiums, and cost-sharing submitted in their approved bids for a given contract year. This final rule also clarifies that MA organizations offering certain kinds of plans restricted to employer and union group health plan sponsors and not open to general enrollment may continue to offer benefit enhancements as they do currently, through means other than midyear benefit enhancements (MYBEs). Programs of all-inclusive care for elderly (PACE) are not subject to the provisions of this final rule and may continue to offer enhanced benefits as specified in our guidance for PACE plans.

34 CFR 75.126 - Application must list all programs to which it is submitted.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 1 2010-07-01 2010-07-01 false Application must list all programs to which it is submitted. 75.126 Section 75.126 Education Office of the Secretary, Department of Education DIRECT GRANT... all programs to which it is submitted. If an applicant is submitting an application for the same...

43 CFR 428.4 - Who must submit forms under this part.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Who must submit forms under this part. 428.4 Section 428.4 Public Lands: Interior Regulations Relating to Public Lands BUREAU OF RECLAMATION... THE ELIGIBILITY OF CERTAIN FORMERLY EXCESS LAND § 428.4 Who must submit forms under this part. (a) You...

30 CFR 1218.560 - How do I submit Form MMS-4444?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 3 2011-07-01 2011-07-01 false How do I submit Form MMS-4444? 1218.560 Section... Service of Official Correspondence § 1218.560 How do I submit Form MMS-4444? A copy of Form MMS-4444 and..., signed form to the address designated on the Form MMS-4444 instructions. ...

30 CFR 254.2 - When must I submit a response plan?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false When must I submit a response plan? 254.2 Section 254.2 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL-SPILL RESPONSE REQUIREMENTS FOR FACILITIES LOCATED SEAWARD OF THE COAST LINE General § 254.2 When must I submit a...

Low-level laser effects on bacterial cultures submitted to heat stress

NASA Astrophysics Data System (ADS)

Gonçalves, E. M.; Guimarães, O. R.; Geller, M.; Paoli, F.; Fonseca, A. S.

2016-06-01

Low-level lasers have been used worldwide to treat a number of diseases, pain relief, and wound healing. Some studies demonstrated that low-level laser radiations induce effects depending on the physiological state and DNA repair mechanisms of cells. In this work we evaluated the effects of low-level red and infrared lasers on Escherichia coli cells deficient in SOS responses submitted to heat stress. Exponential and stationary E. coli cultures of wild type (AB1157), RecA deficient (AB2463) and LexA deficient (AB2494), both SOS response deficient, were exposed to low-level red and infrared lasers at different fluences and submitted to heat stress (42 °C, 20 min). After that, cell survival and morphology were evaluated. Previous exposure to red, but not infrared lasers, increases survival fractions and decreases the area ratios of E. coli AB1157 cells submitted to heat stress. Our research suggests that a low-level red laser increases cell viability and protects cells from morphological alteration in E. coli cultures submitted to heat stress depending on laser wavelength and SOS response.

25 CFR 20.204 - Must all tribes submit a tribal redesign plan?

Code of Federal Regulations, 2010 CFR

2010-04-01

... ASSISTANCE AND SOCIAL SERVICES PROGRAMS Welfare Reform § 20.204 Must all tribes submit a tribal redesign plan? No, you must submit a tribal redesign plan under § 20.206 only if you want to change the way that the...

HMOs must submit Medicare HEDIS.

PubMed

Grimaldi, P L

1997-03-01

Health maintenance organizations (HMOs) are now required to submit the Health Plan Employer Data and Information Set (HEDIS) for Medicare members to the federal government. The information will be used to assess an HMO's stability and performance in meeting its contractual obligations, including providing Medicare members with timely access to quality care. It also may be used to develop explanatory materials for Medicare beneficiaries trying to decide which health plan to join.

Basic Program Elements for Federal employee Occupational Safety and Health Programs and related matters; Subpart I for Recordkeeping and Reporting Requirements. Final rule.

PubMed

2013-08-05

OSHA is issuing a final rule amending the Basic Program Elements to require Federal agencies to submit their occupational injury and illness recordkeeping information to the Bureau of Labor Statistics (BLS) and OSHA on an annual basis. The information, which is already required to be created and maintained by Federal agencies, will be used by BLS to aggregate injury and illness information throughout the Federal government. OSHA will use the information to identify Federal establishments with high incidence rates for targeted inspection, and assist in determining the most effective safety and health training for Federal employees. The final rule also interprets several existing basic program elements in our regulations to clarify requirements applicable to Federal agencies, amends the date when Federal agencies must submit to the Secretary of Labor their annual report on occupational safety and health programs, amends the date when the Secretary of Labor must submit to the President the annual report on Federal agency safety and health, and clarifies that Federal agencies must include uncompensated volunteers when reporting and recording occupational injuries and illnesses.

40 CFR 63.7550 - What reports must I submit and when?

Code of Federal Regulations, 2012 CFR

2012-07-01

... applicable. (6) A signed statement indicating that you burned no new types of fuel. Or, if you did burn a new type of fuel, you must submit the calculation of chlorine input, using Equation 5 of § 63.7530, that... demonstrate compliance through fuel analysis). If you burned a new type of fuel, you must submit the...

30 CFR 1218.560 - How do I submit Form ONRR-4444?

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 3 2014-07-01 2014-07-01 false How do I submit Form ONRR-4444? 1218.560... Service of Official Correspondence § 1218.560 How do I submit Form ONRR-4444? You may obtain a copy of Form ONRR-4444 and instructions from ONRR. This form is posted at http://www.onrr.gov/FM/Forms/default...

30 CFR 1218.560 - How do I submit Form ONRR-4444?

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 3 2013-07-01 2013-07-01 false How do I submit Form ONRR-4444? 1218.560... Service of Official Correspondence § 1218.560 How do I submit Form ONRR-4444? You may obtain a copy of Form ONRR-4444 and instructions from ONRR. This form is posted at http://www.onrr.gov/FM/Forms/default...

30 CFR 254.1 - Who must submit a spill-response plan?

Code of Federal Regulations, 2012 CFR

2012-07-01

... OFFSHORE OIL-SPILL RESPONSE REQUIREMENTS FOR FACILITIES LOCATED SEAWARD OF THE COAST LINE General § 254.1 Who must submit a spill-response plan? (a) If you are the owner or operator of an oil handling... 30 Mineral Resources 2 2012-07-01 2012-07-01 false Who must submit a spill-response plan? 254.1...

30 CFR 254.1 - Who must submit a spill-response plan?

Code of Federal Regulations, 2014 CFR

2014-07-01

... OFFSHORE OIL-SPILL RESPONSE REQUIREMENTS FOR FACILITIES LOCATED SEAWARD OF THE COAST LINE General § 254.1 Who must submit a spill-response plan? (a) If you are the owner or operator of an oil handling... 30 Mineral Resources 2 2014-07-01 2014-07-01 false Who must submit a spill-response plan? 254.1...

30 CFR 254.1 - Who must submit a spill-response plan?

Code of Federal Regulations, 2013 CFR

2013-07-01

... OFFSHORE OIL-SPILL RESPONSE REQUIREMENTS FOR FACILITIES LOCATED SEAWARD OF THE COAST LINE General § 254.1 Who must submit a spill-response plan? (a) If you are the owner or operator of an oil handling... 30 Mineral Resources 2 2013-07-01 2013-07-01 false Who must submit a spill-response plan? 254.1...

Final Report for NIREC Renewable Energy Research & Development Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Borland, Walt

This report is a compilation of progress reports and presentations submitted by NIREC to the DOE’s Solar Energy Technologies Office for award number DE-FG36-08GO88161. This compilation has been uploaded to OSTI by DOE as a substitute for the required Final Technical Report, which was not submitted to DOE by NIREC or received by DOE. Project Objective: The primary goal of NIREC is to advance the transformation of the scientific innovation of the institutional partner’s research in renewable energy into a proof of the scientific concept eventually leading to viable businesses with cost effective solutions to accelerate the widespread adoption ofmore » renewable energy. NIREC will a) select research projects that are determined to have significant commercialization potential as a result of vetting by the Technology and commercialization Advisory Board, b) assign an experienced Entrepreneur-in-Residence (EIR) to each manage the scientific commercialization-preparedness process, and c) facilitate connectivity with venture capital and other private-sector capital sources to fund the rollout, scaling and growth of the resultant renewable energy business.« less

Improve Tracking of Workplace Injuries and Illnesses. Final rule.

PubMed

2016-05-12

OSHA is issuing a final rule to revise its Recording and Reporting Occupational Injuries and Illnesses regulation. The final rule requires employers in certain industries to electronically submit to OSHA injury and illness data that employers are already required to keep under existing OSHA regulations. The frequency and content of these establishment-specific submissions is set out in the final rule and is dependent on the size and industry of the employer. OSHA intends to post the data from these submissions on a publicly accessible Web site. OSHA does not intend to post any information on the Web site that could be used to identify individual employees. The final rule also amends OSHA's recordkeeping regulation to update requirements on how employers inform employees to report work-related injuries and illnesses to their employer. The final rule requires employers to inform employees of their right to report work-related injuries and illnesses free from retaliation; clarifies the existing implicit requirement that an employer's procedure for reporting work-related injuries and illnesses must be reasonable and not deter or discourage employees from reporting; and incorporates the existing statutory prohibition on retaliating against employees for reporting work-related injuries or illnesses. The final rule also amends OSHA's existing recordkeeping regulation to clarify the rights of employees and their representatives to access the injury and illness records.

78 FR 33341 - Certain New Pneumatic Off-the-Road Tires From the People's Republic of China: Final Results of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-04

... expense for Trelleborg Wheel Systems China's raw materials purchased in market economies, and replaced... economy purchases, per information Trelleborg Wheel Systems China submitted after the Preliminary Results...-the-Road Tires From the People's Republic of China: Final Results of Antidumping Duty New Shipper...

48 CFR 801.602-84 - Documents to submit for business clearance reviews.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Development, Contracting Authority, and Responsibilities 801.602-84 Documents to submit for business clearance reviews. A contracting officer must submit to Acquisition Resources Service (Office of Construction and... the vendor is not suspended, debarred, or on the Department of Health and Human Services Exclusionary...

48 CFR 801.602-84 - Documents to submit for business clearance reviews.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Development, Contracting Authority, and Responsibilities 801.602-84 Documents to submit for business clearance reviews. A contracting officer must submit to Acquisition Resources Service (Office of Construction and... the vendor is not suspended, debarred, or on the Department of Health and Human Services Exclusionary...

48 CFR 801.602-84 - Documents to submit for business clearance reviews.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Development, Contracting Authority, and Responsibilities 801.602-84 Documents to submit for business clearance reviews. A contracting officer must submit to Acquisition Resources Service (Office of Construction and... the vendor is not suspended, debarred, or on the Department of Health and Human Services Exclusionary...

48 CFR 801.602-84 - Documents to submit for business clearance reviews.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Development, Contracting Authority, and Responsibilities 801.602-84 Documents to submit for business clearance reviews. A contracting officer must submit to Acquisition Resources Service (Office of Construction and... the vendor is not suspended, debarred, or on the Department of Health and Human Services Exclusionary...

21 CFR 720.7 - Notification of person submitting cosmetic product ingredient statement.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 7 2012-04-01 2012-04-01 false Notification of person submitting cosmetic product... AND HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY FILING OF COSMETIC PRODUCT INGREDIENT COMPOSITION STATEMENTS § 720.7 Notification of person submitting cosmetic product ingredient statement. When Form FDA...

21 CFR 720.7 - Notification of person submitting cosmetic product ingredient statement.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 7 2011-04-01 2010-04-01 true Notification of person submitting cosmetic product... AND HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY FILING OF COSMETIC PRODUCT INGREDIENT COMPOSITION STATEMENTS § 720.7 Notification of person submitting cosmetic product ingredient statement. When Form FDA...

21 CFR 720.7 - Notification of person submitting cosmetic product ingredient statement.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 7 2014-04-01 2014-04-01 false Notification of person submitting cosmetic product... AND HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY FILING OF COSMETIC PRODUCT INGREDIENT COMPOSITION STATEMENTS § 720.7 Notification of person submitting cosmetic product ingredient statement. When Form FDA...

21 CFR 720.7 - Notification of person submitting cosmetic product ingredient statement.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Notification of person submitting cosmetic product... AND HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY FILING OF COSMETIC PRODUCT INGREDIENT COMPOSITION STATEMENTS § 720.7 Notification of person submitting cosmetic product ingredient statement. When Form FDA...

21 CFR 720.7 - Notification of person submitting cosmetic product ingredient statement.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 7 2013-04-01 2013-04-01 false Notification of person submitting cosmetic product... AND HUMAN SERVICES (CONTINUED) COSMETICS VOLUNTARY FILING OF COSMETIC PRODUCT INGREDIENT COMPOSITION STATEMENTS § 720.7 Notification of person submitting cosmetic product ingredient statement. When Form FDA...

Final report of the independent counsel for Iran/Contra matters. Volume 3: Comments and materials submitted by individuals and their attorneys responding to volume 1 of the final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Walsh, L.E.

1993-08-04

In October and November 1986, two secret U.S. Government operations were publicly exposed, potentially implicating Reagan Administration officials in illegal activities. These operations were the provision of assistance to the military activities of the Nicaraguan contra rebels during an October 1984 to October 1986 prohibition on such aid, and the sale of U.S. arms to Iran in contravention of stated U.S. policy and in possible violation of arms-export controls. In late November 1986, Reagan Administration officials announced that some of the proceeds from the sale of U.S. arms to Iran had been diverted to the contras. As a result, Attorneymore » General Edwin Meese III sought the appointment of an independent counsel to investigate and prosecute possible crimes. Volume III contains comments and materials submitted by individuals and their attorneys from that investigation.« less

32 CFR Appendix C to Part 284 - Submitting a Waiver Application

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 2 2010-07-01 2010-07-01 false Submitting a Waiver Application C Appendix C to... Pt. 284, App. C Appendix C to Part 284—Submitting a Waiver Application A. Who May Apply for Waiver... under 10 U.S.C. 2774, 32 U.S.C. 716, and 5 U.S.C. 5584. Additionally, an authorized official of the...

30 CFR 1218.560 - How do I submit Form MMS-4444?

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 3 2012-07-01 2012-07-01 false How do I submit Form MMS-4444? 1218.560 Section... Service of Official Correspondence § 1218.560 How do I submit Form MMS-4444? You may obtain a copy of Form MMS-4444 and instructions from ONRR. This form is posted at http://www.onrr.gov/FM/Forms/default.htm...

40 CFR 63.1574 - What notifications must I submit and when?

Code of Federal Regulations, 2010 CFR

2010-07-01

... catalytic reforming unit when you use a colormetric tube sampling system, including procedures for..., you must submit all of the notifications in §§ 63.6(h), 63.7(b) and (c), 63.8(e), 63.8(f)(4), 63.8(f)(6), and 63.9(b) through (h) that apply to you by the dates specified. (1) You must submit the...

41 CFR 102-75.855 - What happens if DOT does not submit an assignment recommendation?

Code of Federal Regulations, 2010 CFR

2010-07-01

... not submit an assignment recommendation? 102-75.855 Section 102-75.855 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION REAL....855 What happens if DOT does not submit an assignment recommendation? If DOT does not submit an...

43 CFR 3835.92 - What if I fail to submit a timely waiver request?

Code of Federal Regulations, 2011 CFR

2011-10-01

... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false What if I fail to submit a timely waiver... MAINTENANCE FEES Defective Waivers and FLPMA Filings § 3835.92 What if I fail to submit a timely waiver request? (a) If you fail to submit a qualified waiver request (see § 3835.1) and also fail to pay an...

43 CFR 3835.92 - What if I fail to submit a timely waiver request?

Code of Federal Regulations, 2013 CFR

2013-10-01

... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false What if I fail to submit a timely waiver... MAINTENANCE FEES Defective Waivers and FLPMA Filings § 3835.92 What if I fail to submit a timely waiver request? (a) If you fail to submit a qualified waiver request (see § 3835.1) and also fail to pay an...

43 CFR 3835.92 - What if I fail to submit a timely waiver request?

Code of Federal Regulations, 2012 CFR

2012-10-01

... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false What if I fail to submit a timely waiver... MAINTENANCE FEES Defective Waivers and FLPMA Filings § 3835.92 What if I fail to submit a timely waiver request? (a) If you fail to submit a qualified waiver request (see § 3835.1) and also fail to pay an...

43 CFR 3835.92 - What if I fail to submit a timely waiver request?

Code of Federal Regulations, 2014 CFR

2014-10-01

... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false What if I fail to submit a timely waiver... MAINTENANCE FEES Defective Waivers and FLPMA Filings § 3835.92 What if I fail to submit a timely waiver request? (a) If you fail to submit a qualified waiver request (see § 3835.1) and also fail to pay an...

49 CFR Appendix II to Part 805 - Employees Required To Submit Statements

Code of Federal Regulations, 2010 CFR

2010-10-01

...—Employees Required To Submit Statements Statements of employment and financial interests are required of the... 49 Transportation 7 2010-10-01 2010-10-01 false Employees Required To Submit Statements II...) Office of the managing director: (1) Legislative affairs officer. (2) Program analysis officer. (d...

30 CFR 553.40 - What OSFR evidence must I submit to BOEM?

Code of Federal Regulations, 2013 CFR

2013-07-01

... 30 Mineral Resources 2 2013-07-01 2013-07-01 false What OSFR evidence must I submit to BOEM? 553.40 Section 553.40 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL SPILL FINANCIAL RESPONSIBILITY FOR OFFSHORE FACILITIES Requirements for Submitting OSFR...

30 CFR 253.40 - What OSFR evidence must I submit to MMS?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What OSFR evidence must I submit to MMS? 253.40 Section 253.40 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL SPILL FINANCIAL RESPONSIBILITY FOR OFFSHORE FACILITIES Requirements for Submitting OSFR Information...

30 CFR 553.40 - What OSFR evidence must I submit to BOEM?

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 2 2012-07-01 2012-07-01 false What OSFR evidence must I submit to BOEM? 553.40 Section 553.40 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL SPILL FINANCIAL RESPONSIBILITY FOR OFFSHORE FACILITIES Requirements for Submitting OSFR...

30 CFR 553.40 - What OSFR evidence must I submit to BOEM?

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 2 2014-07-01 2014-07-01 false What OSFR evidence must I submit to BOEM? 553.40 Section 553.40 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE OIL SPILL FINANCIAL RESPONSIBILITY FOR OFFSHORE FACILITIES Requirements for Submitting OSFR...

40 CFR 60.1385 - What reports must I submit after I submit my notice of construction and in what form?

Code of Federal Regulations, 2014 CFR

2014-07-01

... SOURCES Standards of Performance for Small Municipal Waste Combustion Units for Which Construction is... may submit electronic reports. (c) Keep a copy of all reports required by §§ 60.1400, 60.1410, and 60...

40 CFR 60.1385 - What reports must I submit after I submit my notice of construction and in what form?

Code of Federal Regulations, 2011 CFR

2011-07-01

... SOURCES Standards of Performance for Small Municipal Waste Combustion Units for Which Construction is... may submit electronic reports. (c) Keep a copy of all reports required by §§ 60.1400, 60.1410, and 60...

40 CFR 60.1385 - What reports must I submit after I submit my notice of construction and in what form?

Code of Federal Regulations, 2012 CFR

2012-07-01

... SOURCES Standards of Performance for Small Municipal Waste Combustion Units for Which Construction is... may submit electronic reports. (c) Keep a copy of all reports required by §§ 60.1400, 60.1410, and 60...

40 CFR 60.1385 - What reports must I submit after I submit my notice of construction and in what form?

Code of Federal Regulations, 2010 CFR

2010-07-01

... SOURCES Standards of Performance for Small Municipal Waste Combustion Units for Which Construction is... may submit electronic reports. (c) Keep a copy of all reports required by §§ 60.1400, 60.1410, and 60...

40 CFR 60.1385 - What reports must I submit after I submit my notice of construction and in what form?

Code of Federal Regulations, 2013 CFR

2013-07-01

... SOURCES Standards of Performance for Small Municipal Waste Combustion Units for Which Construction is... may submit electronic reports. (c) Keep a copy of all reports required by §§ 60.1400, 60.1410, and 60...

Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.

PubMed

Lu, Ying; Wu, Jiayi; Dong, Yuanchen; Chen, Shuobing; Sun, Shuangwu; Ma, Yong-Bei; Ouyang, Qi; Finley, Daniel; Kirschner, Marc W; Mao, Youdong

2017-07-20

The proteasome holoenzyme is activated by its regulatory particle (RP) consisting of two subcomplexes, the lid and the base. A key event in base assembly is the formation of a heterohexameric ring of AAA-ATPases, which is guided by at least four RP assembly chaperones in mammals: PAAF1, p28/gankyrin, p27/PSMD9, and S5b. Using cryogenic electron microscopy, we analyzed the non-AAA structure of the p28-bound human RP at 4.5 Å resolution and determined seven distinct conformations of the Rpn1-p28-AAA subcomplex within the p28-bound RP at subnanometer resolutions. Remarkably, the p28-bound AAA ring does not form a channel in the free RP and spontaneously samples multiple "open" and "closed" topologies at the Rpt2-Rpt6 and Rpt3-Rpt4 interfaces. Our analysis suggests that p28 assists the proteolytic core particle to select a specific conformation of the ATPase ring for RP engagement and is released in a shoehorn-like fashion in the last step of the chaperone-mediated proteasome assembly. Copyright © 2017 Elsevier Inc. All rights reserved.

Early Blindness Results in Developmental Plasticity for Auditory Motion Processing within Auditory and Occipital Cortex

PubMed Central

Jiang, Fang; Stecker, G. Christopher; Boynton, Geoffrey M.; Fine, Ione

2016-01-01

Early blind subjects exhibit superior abilities for processing auditory motion, which are accompanied by enhanced BOLD responses to auditory motion within hMT+ and reduced responses within right planum temporale (rPT). Here, by comparing BOLD responses to auditory motion in hMT+ and rPT within sighted controls, early blind, late blind, and sight-recovery individuals, we were able to separately examine the effects of developmental and adult visual deprivation on cortical plasticity within these two areas. We find that both the enhanced auditory motion responses in hMT+ and the reduced functionality in rPT are driven by the absence of visual experience early in life; neither loss nor recovery of vision later in life had a discernable influence on plasticity within these areas. Cortical plasticity as a result of blindness has generally be presumed to be mediated by competition across modalities within a given cortical region. The reduced functionality within rPT as a result of early visual loss implicates an additional mechanism for cross modal plasticity as a result of early blindness—competition across different cortical areas for functional role. PMID:27458357

22 CFR 304.4 - Administrative claim; evidence and information to be submitted.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Administrative claim; evidence and information to be submitted. 304.4 Section 304.4 Foreign Relations PEACE CORPS CLAIMS AGAINST GOVERNMENT UNDER FEDERAL TORT CLAIMS ACT Procedures § 304.4 Administrative claim; evidence and information to be submitted...

22 CFR 304.4 - Administrative claim; evidence and information to be submitted.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Administrative claim; evidence and information to be submitted. 304.4 Section 304.4 Foreign Relations PEACE CORPS CLAIMS AGAINST GOVERNMENT UNDER FEDERAL TORT CLAIMS ACT Procedures § 304.4 Administrative claim; evidence and information to be submitted...

20 CFR 669.510 - What planning documents must an NFJP grantee submit?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false What planning documents must an NFJP grantee submit? 669.510 Section 669.510 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF... Accountability, Planning and Waiver Provision § 669.510 What planning documents must an NFJP grantee submit? Each...

7 CFR 75.20 - Submitted sample inspection.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 3 2013-01-01 2013-01-01 false Submitted sample inspection. 75.20 Section 75.20 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 194...

7 CFR 75.20 - Submitted sample inspection.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Submitted sample inspection. 75.20 Section 75.20 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 194...

7 CFR 75.20 - Submitted sample inspection.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 3 2014-01-01 2014-01-01 false Submitted sample inspection. 75.20 Section 75.20 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 194...

7 CFR 75.20 - Submitted sample inspection.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 3 2012-01-01 2012-01-01 false Submitted sample inspection. 75.20 Section 75.20 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 194...

7 CFR 75.20 - Submitted sample inspection.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 3 2011-01-01 2011-01-01 false Submitted sample inspection. 75.20 Section 75.20 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 194...

Content Analysis of Papers Submitted to "Communications in Information Literacy," 2007-2013

ERIC Educational Resources Information Center

Hollister, Christopher V.

2014-01-01

The author conducted a content analysis of papers submitted to the journal, "Communications in Information Literacy," from the years 2007-2013. The purpose was to investigate and report on the overall quality characteristics of a statistically significant sample of papers submitted to a single-topic, open access, library and information…

40 CFR 60.2755 - When must I submit my waste management plan?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 6 2010-07-01 2010-07-01 false When must I submit my waste management... waste management plan? You must submit the waste management plan no later than the date specified in... Compliance Times for Commercial and Industrial Solid Waste Incineration Units that Commenced Construction On...

40 CFR 60.2060 - When must I submit my waste management plan?

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 7 2013-07-01 2013-07-01 false When must I submit my waste management plan? 60.2060 Section 60.2060 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Commercial and Industrial Solid Waste Incineration Units Waste Management Plan § 60.2060 When must I submit...

40 CFR 60.2060 - When must I submit my waste management plan?

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 7 2014-07-01 2014-07-01 false When must I submit my waste management plan? 60.2060 Section 60.2060 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Commercial and Industrial Solid Waste Incineration Units Waste Management Plan § 60.2060 When must I submit...

40 CFR 60.2755 - When must I submit my waste management plan?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 6 2011-07-01 2011-07-01 false When must I submit my waste management... waste management plan? You must submit the waste management plan no later than the date specified in... Compliance Times for Commercial and Industrial Solid Waste Incineration Units that Commenced Construction On...

40 CFR 60.2235 - In what form can I submit my reports?

Code of Federal Regulations, 2012 CFR

2012-07-01

... opacity data, electronically to EPA's Central Data Exchange (CDX) by using the Electronic Reporting Tool (ERT) (see http://www.epa.gov/ttn/chief/ert/ert tool.html/) or other compatible electronic spreadsheet... Recordkeeping and Reporting § 60.2235 In what form can I submit my reports? Submit initial, annual, and...

40 CFR 60.2235 - In what form can I submit my reports?

Code of Federal Regulations, 2011 CFR

2011-07-01

... opacity data, electronically to EPA's Central Data Exchange (CDX) by using the Electronic Reporting Tool (ERT) (see http://www.epa.gov/ttn/chief/ert/ert tool.html/) or other compatible electronic spreadsheet... Recordkeeping and Reporting § 60.2235 In what form can I submit my reports? Submit initial, annual, and...

40 CFR 62.14585 - When must I submit my waste management plan?

Code of Federal Regulations, 2011 CFR

2011-07-01

... POLLUTANTS Federal Plan Requirements for Commercial and Industrial Solid Waste Incineration Units That Commenced Construction On or Before November 30, 1999 Waste Management Plan § 62.14585 When must I submit my... 40 Protection of Environment 8 2011-07-01 2011-07-01 false When must I submit my waste management...

Emerging Trends in the Volume and Format of Outside Examinations Submitted for Secondary Interpretation

PubMed Central

Hunt, Christopher H.; Wood, Christopher P.; Diehn, Felix E.; Eckel, Laurence J.; Schwartz, Kara M.; Erickson, Bradley J.

2014-01-01

OBJECTIVE The purpose of this article is to describe the trends of secondary interpretations, including the total volume and format of cases. MATERIALS AND METHODS This retrospective study involved all outside neuroradiology examinations submitted for secondary interpretation from November 2006 through December 2010. This practice utilizes consistent criteria and includes all images that cover the brain, neck, and spine. For each month, the total number of outside examinations and their format (i.e., hard-copy film, DICOM CD-ROM, or non-DICOM CD-ROM) were recorded. RESULTS There was no significant change in the volume of cases (1043 ± 131 cases/month; p = 0.46, two-sided Student t test). There was a significant decrease in the volume of hard-copy films submitted, with the mean number of examinations submitted per month on hard-copy film declining from 297 in 2007 to 57 in 2010 (p < 0.0001, Student t test). This decrease was mirrored by an increase in the mean number of cases submitted on CD-ROM (753 cases/month in 2007 and 1036 cases/month in 2010; p < 0.0001). Although most were submitted in DICOM format, there was almost a doubling of the volume of cases submitted on non-DICOM CD-ROM (mean number of non-DICOM CD-ROMs, nine cases/month in 2007 and 17 cases/month in 2010; p < 0.001). CONCLUSION There has been a significant decrease in the number of hard-copy films submitted for secondary interpretation. There has been almost a doubling of the volume of cases submitted in non-DICOM formats, which is unfortunate, given the many advantages of the internationally derived DICOM standard, including ease of archiving, standardized display, efficient review, improved interpretation, and quality of patient care. PMID:22451538

Emerging trends in the volume and format of outside examinations submitted for secondary interpretation.

PubMed

Hunt, Christopher H; Wood, Christopher P; Diehn, Felix E; Eckel, Laurence J; Schwartz, Kara M; Erickson, Bradley J

2012-04-01

The purpose of this article is to describe the trends of secondary interpretations, including the total volume and format of cases. This retrospective study involved all outside neuroradiology examinations submitted for secondary interpretation from November 2006 through December 2010. This practice utilizes consistent criteria and includes all images that cover the brain, neck, and spine. For each month, the total number of outside examinations and their format (i.e., hard-copy film, DICOM CD-ROM, or non-DICOM CD-ROM) were recorded. There was no significant change in the volume of cases (1043 ± 131 cases/month; p = 0.46, two-sided Student t test). There was a significant decrease in the volume of hard-copy films submitted, with the mean number of examinations submitted per month on hard-copy film declining from 297 in 2007 to 57 in 2010 (p < 0.0001, Student t test). This decrease was mirrored by an increase in the mean number of cases submitted on CD-ROM (753 cases/month in 2007 and 1036 cases/month in 2010; p < 0.0001). Although most were submitted in DICOM format, there was almost a doubling of the volume of cases submitted on non-DICOM CD-ROM (mean number of non-DICOM CD-ROMs, nine cases/month in 2007 and 17 cases/month in 2010; p < 0.001). There has been a significant decrease in the number of hard-copy films submitted for secondary interpretation. There has been almost a doubling of the volume of cases submitted in non-DICOM formats, which is unfortunate, given the many advantages of the internationally derived DICOM standard, including ease of archiving, standardized display, efficient review, improved interpretation, and quality of patient care.

78 FR 6150 - Agency Forms Submitted for OMB Review, Request for Comments

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-29

... required to submit reports of employee service and compensation to the RRB as needed for administering the... home addresses of all employees hired within the last year (new-hires). Form BA-6a, Form BA-6 Address.... The form also serves as an instruction sheet to railroad employers who can submit the information...

25 CFR 20.204 - Must all tribes submit a tribal redesign plan?

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 1 2012-04-01 2011-04-01 true Must all tribes submit a tribal redesign plan? 20.204 Section 20.204 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HUMAN SERVICES FINANCIAL ASSISTANCE AND SOCIAL SERVICES PROGRAMS Welfare Reform § 20.204 Must all tribes submit a tribal redesign plan...

25 CFR 20.204 - Must all tribes submit a tribal redesign plan?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 1 2011-04-01 2011-04-01 false Must all tribes submit a tribal redesign plan? 20.204 Section 20.204 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HUMAN SERVICES FINANCIAL ASSISTANCE AND SOCIAL SERVICES PROGRAMS Welfare Reform § 20.204 Must all tribes submit a tribal redesign plan...

25 CFR 20.204 - Must all tribes submit a tribal redesign plan?

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 1 2013-04-01 2013-04-01 false Must all tribes submit a tribal redesign plan? 20.204 Section 20.204 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HUMAN SERVICES FINANCIAL ASSISTANCE AND SOCIAL SERVICES PROGRAMS Welfare Reform § 20.204 Must all tribes submit a tribal redesign plan...

25 CFR 20.204 - Must all tribes submit a tribal redesign plan?

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 1 2014-04-01 2014-04-01 false Must all tribes submit a tribal redesign plan? 20.204 Section 20.204 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HUMAN SERVICES FINANCIAL ASSISTANCE AND SOCIAL SERVICES PROGRAMS Welfare Reform § 20.204 Must all tribes submit a tribal redesign plan...

40 CFR 60.2625 - When must I submit my waste management plan?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 6 2010-07-01 2010-07-01 false When must I submit my waste management... Compliance Times for Commercial and Industrial Solid Waste Incineration Units that Commenced Construction On or Before November 30, 1999 Model Rule-Waste Management Plan § 60.2625 When must I submit my waste...

How to Submit | Center for Cancer Research

Cancer.gov

be submitted by a current NIH or FDA fellow. The work does not need to have been done at the NIH/FDA. However, the submitter must be an author on the document and be in compliance with the intended journal's authorship guidelines or general good authorship practices. 

18 CFR 154.302 - Previously submitted material.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Previously submitted material. 154.302 Section 154.302 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... concurrently with the rate change filing. There must be furnished to the Director, Office of Energy Market...

30 CFR 1210.201 - How do I submit Form MMS-4430, Solid Minerals Production and Royalty Report?

Code of Federal Regulations, 2011 CFR

2011-07-01

...) Instructions for completing and submitting Form MMS-4430 are available on our Internet reporting web site or you may contact us toll free at 1-888-201-6416. (b) When to submit. (1) Unless your lease terms... month. (c) How to submit. (1) You must submit Form MMS-4430 electronically using our Internet reporting...

Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Callis, Judy

This report summarizes our research activities. In the award period, we have made significant progress on the first aim, with new discoveries reported in one published paper (1) and in one submitted manuscript (2) currently under review. The published manuscript reports on our discovery of plant ribokinase and the metabolic pathway in which it functions; the submitted manuscript is identification and characterization of the plant fructokinase family of enzymes from expression studies, sequence comparisons, subcellular localizations and enzymatic activities of recombinant proteins. Our study of loss-of-function mutants in the fructokinase family members (2) revealed that there were no phenotypic differencesmore » observed for the five genes analyzed, so we have adopted the Crispr/Cas9 system to isolate mutants in the two genes for which there are no currently available insertion mutants, and we are generating higher order mutants (double, triples, etc) to discern the relative roles and significance for each fructokinase. These mutants will be an important resource to understand regulation of carbohydrate movement and catabolism in plants. As studies from others indicate, alteration of fructokinases results in changes in cell walls and vasculatures, which have importance relative to biofuel yield and quality. In the second aim, we have characterized the protein-protein interactions for the pkfB proteins FLN1 and FLN2 that are localized to chloroplast transcriptional complexes and have proposed a new model for how chloroplast transcription is regulated. This work has been submitted for publication, been revised and will be re-submitted in December 2016« less

75 FR 60404 - Information Collection Request Submitted to Office of Management and Budget

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-30

... [OMB Control Number: 3002-0003] Information Collection Request Submitted to Office of Management and... United States will submit an Information Collection Request (ICR) to the Office of Management and Budget (OMB) requesting approval for the following collection of information: 3002-0003, Substitute...

49 CFR 199.223 - Refusal to submit to a required alcohol test.

Code of Federal Regulations, 2010 CFR

2010-10-01

... required alcohol test. Each operator shall require a covered employee to submit to a post-accident alcohol test required under § 199.225(a), a reasonable suspicion alcohol test required under § 199.225(b), or a... 49 Transportation 3 2010-10-01 2010-10-01 false Refusal to submit to a required alcohol test. 199...

49 CFR 199.223 - Refusal to submit to a required alcohol test.

Code of Federal Regulations, 2011 CFR

2011-10-01

... required alcohol test. Each operator shall require a covered employee to submit to a post-accident alcohol test required under § 199.225(a), a reasonable suspicion alcohol test required under § 199.225(b), or a... 49 Transportation 3 2011-10-01 2011-10-01 false Refusal to submit to a required alcohol test. 199...

49 CFR 199.223 - Refusal to submit to a required alcohol test.

Code of Federal Regulations, 2014 CFR

2014-10-01

... required alcohol test. Each operator shall require a covered employee to submit to a post-accident alcohol test required under § 199.225(a), a reasonable suspicion alcohol test required under § 199.225(b), or a... 49 Transportation 3 2014-10-01 2014-10-01 false Refusal to submit to a required alcohol test. 199...

49 CFR 199.223 - Refusal to submit to a required alcohol test.

Code of Federal Regulations, 2012 CFR

2012-10-01

... required alcohol test. Each operator shall require a covered employee to submit to a post-accident alcohol test required under § 199.225(a), a reasonable suspicion alcohol test required under § 199.225(b), or a... 49 Transportation 3 2012-10-01 2012-10-01 false Refusal to submit to a required alcohol test. 199...

49 CFR 199.223 - Refusal to submit to a required alcohol test.

Code of Federal Regulations, 2013 CFR

2013-10-01

... required alcohol test. Each operator shall require a covered employee to submit to a post-accident alcohol test required under § 199.225(a), a reasonable suspicion alcohol test required under § 199.225(b), or a... 49 Transportation 3 2013-10-01 2013-10-01 false Refusal to submit to a required alcohol test. 199...

76 FR 71389 - Agency Forms Submitted for OMB Review, Request for Comments

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-17

... techniques or other forms of information technology. Comments to the RRB or OIRA must contain the OMB control... equivalent version of Form BA-3 that can be submitted through the ERS which will include the option to file a.../System Access Application. OMB Control Number: 3220-0008. Forms Submitted: BA-3, BA-3 (Internet), BA-4...

A tolerance gene for prenylated flavonoid encodes a 26S proteasome regulatory subunit in Sophora flavescens.

PubMed

Shitan, Nobukazu; Kamimoto, Yoshihisa; Minami, Shota; Kubo, Mizuki; Ito, Kozue; Moriyasu, Masataka; Yazaki, Kazufumi

2011-01-01

Yeast functional screening with a Sophora flavescens cDNA library was performed to identify the genes involved in the tolerant mechanism to the self-producing prenylated flavonoid sophoraflavanone G (SFG). One cDNA, which conferred SFG tolerance, encoded a regulatory particle triple-A ATPase 2 (SfRPT2), a member of the 26S proteasome subunit. The yeast transformant of SfRPT2 showed reduced SFG accumulation in the cells.

76 FR 75894 - Information Collection Activities: Pipelines and Pipeline Rights-of-Way; Submitted for Office of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-05

... pipelines `` * * * for the transportation of oil, natural gas, sulphur, or other minerals, or under such...) Submit repair report 3 1008(f) Submit report of pipeline failure analysis...... 30 1008(g) Submit plan of.... BSEE-2011-0002; OMB Control Number 1010-0050] Information Collection Activities: Pipelines and Pipeline...

27 CFR 73.34 - When is an electronically submitted form considered timely filed?

Code of Federal Regulations, 2010 CFR

2010-04-01

... AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY (CONTINUED) PROCEDURES AND PRACTICES ELECTRONIC SIGNATURES; ELECTRONIC SUBMISSION OF FORMS Electronic Filing of Documents with TTB § 73.34 When is an electronically submitted form considered timely filed? If you submit a form to our electronic...

43 CFR 3266.10 - Will BLM disclose information I submit under these regulations?

Code of Federal Regulations, 2012 CFR

2012-10-01

... public disclosure of data and information contained in Department records. Certain mineral information not protected from disclosure under part 2 of this title may be made available for inspection without... submit under these regulations? All Federal and Indian data and information submitted to the BLM are...

43 CFR 3255.10 - Will BLM disclose information I submit under these regulations?

Code of Federal Regulations, 2012 CFR

2012-10-01

... covering public disclosure of data and information contained in Department records. Certain mineral information not protected from disclosure under part 2 may be made available for inspection without a Freedom... submit under these regulations? All Federal and Indian data and information submitted to the BLM are...

43 CFR 3255.10 - Will BLM disclose information I submit under these regulations?

Code of Federal Regulations, 2013 CFR

2013-10-01

... covering public disclosure of data and information contained in Department records. Certain mineral information not protected from disclosure under part 2 may be made available for inspection without a Freedom... submit under these regulations? All Federal and Indian data and information submitted to the BLM are...

43 CFR 3266.10 - Will BLM disclose information I submit under these regulations?

Code of Federal Regulations, 2013 CFR

2013-10-01

... public disclosure of data and information contained in Department records. Certain mineral information not protected from disclosure under part 2 of this title may be made available for inspection without... submit under these regulations? All Federal and Indian data and information submitted to the BLM are...

24 CFR 3282.354 - Submittal of false information or refusal to submit information.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Submittal of false information or... ENFORCEMENT REGULATIONS Primary Inspection Agencies § 3282.354 Submittal of false information or refusal to submit information. The submittal of false information or the refusal to submit information required...

Submitting for Dollars: Playing the Funding Game to Promote Transcultural Nursing.

PubMed

Amerson, Roxanne

2015-07-01

Research requires funding! Every researcher understands the crucial role that money plays in implementing a research study. Research for nursing is no different. In the current economic environment, funding sources have become limited. Therefore, researchers need to be prepared to submit grant proposals which will give them a competitive edge over other proposals. This paper will: (1) describe the development of a grant proposal for National Institutes of Health funding, and (2) provide suggestions to novice researchers about how to write a proposal that has the potential to receive a fundable score. This team of early stage investigators submitted a proposal which received a fundable score, but was not selected for funding. The proposal was revised, re-submitted, and received a highly competitive score that did result in funding. The lessons learned from this process can be useful for other nurses seeking to secure funding for their research projects.

7 CFR 28.954 - Costs of submitting samples.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 2 2010-01-01 2010-01-01 false Costs of submitting samples. 28.954 Section 28.954 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE COMMODITY STANDARDS AND STANDARD CONTAINER...

40 CFR 60.2953 - What information must I submit prior to initial startup?

Code of Federal Regulations, 2013 CFR

2013-07-01

... initial startup? 60.2953 Section 60.2953 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... and Reporting § 60.2953 What information must I submit prior to initial startup? You must submit the information specified in paragraphs (a) through (e) of this section prior to initial startup. (a) The type(s...

40 CFR 60.2195 - What information must I submit prior to initial startup?

Code of Federal Regulations, 2014 CFR

2014-07-01

... initial startup? 60.2195 Section 60.2195 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... What information must I submit prior to initial startup? You must submit the information specified in paragraphs (a) through (e) of this section prior to initial startup. (a) The type(s) of waste to be burned...

40 CFR 60.2953 - What information must I submit prior to initial startup?

Code of Federal Regulations, 2014 CFR

2014-07-01

... initial startup? 60.2953 Section 60.2953 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... and Reporting § 60.2953 What information must I submit prior to initial startup? You must submit the information specified in paragraphs (a) through (e) of this section prior to initial startup. (a) The type(s...

40 CFR 60.2195 - What information must I submit prior to initial startup?

Code of Federal Regulations, 2013 CFR

2013-07-01

... initial startup? 60.2195 Section 60.2195 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... What information must I submit prior to initial startup? You must submit the information specified in paragraphs (a) through (e) of this section prior to initial startup. (a) The type(s) of waste to be burned...

78 FR 75563 - Application for Final Commitment for a Long-Term Loan or Financial Guarantee in Excess of $100...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-12

... EXPORT-IMPORT BANK [Public Notice: 2013-0058] Application for Final Commitment for a Long-Term.... To submit a comment, enter EIB-2013-0058 under the heading ``Enter Keyword or ID'' and select Search... (if any) and EIB-2013-0058 on any attached document. Reference: AP088406XX. Purpose and Use: Brief...

15 CFR 270.351 - Protection of voluntarily submitted information.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Protection of voluntarily submitted information. Notwithstanding any other provision of law, a Team, NIST, any investigation participant, and any agency receiving information from a Team, NIST, or any other...

EPA Materials Submitted to the National Research Council

EPA Pesticide Factsheets

This is a 2-part report submitted to the National Research Council in response to a review of the EPA IRIS assessment development program. It includes the preamble to the assessment as well as a handbook for the development of new re-assessments.

The repeat domain of the melanosome fibril protein Pmel17 forms the amyloid core promoting melanin synthesis

PubMed Central

McGlinchey, Ryan P.; Shewmaker, Frank; McPhie, Peter; Monterroso, Begoña; Thurber, Kent; Wickner, Reed B.

2009-01-01

Pmel17 is a melanocyte protein necessary for eumelanin deposition 1 in mammals and found in melanosomes in a filamentous form. The luminal part of human Pmel17 includes a region (RPT) with 10 copies of a partial repeat sequence, pt.e.gttp.qv., known to be essential in vivo for filament formation. We show that this RPT region readily forms amyloid in vitro, but only under the mildly acidic conditions typical of the lysosome-like melanosome lumen, and the filaments quickly become soluble at neutral pH. Under the same mildly acidic conditions, the Pmel filaments promote eumelanin formation. Electron diffraction, circular dichroism, and solid-state NMR studies of Pmel17 filaments show that the structure is rich in beta sheet. We suggest that RPT is the amyloid core domain of the Pmel17 filaments so critical for melanin formation. PMID:19666488

44 CFR 204.22 - Submitting a request for a fire management assistance declaration.

Code of Federal Regulations, 2014 CFR

2014-10-01

... ASSISTANCE GRANT PROGRAM Declaration Process § 204.22 Submitting a request for a fire management assistance.... To ensure that we can process a State's request for a fire management assistance declaration as... 44 Emergency Management and Assistance 1 2014-10-01 2014-10-01 false Submitting a request for a...

44 CFR 204.22 - Submitting a request for a fire management assistance declaration.

Code of Federal Regulations, 2011 CFR

2011-10-01

... ASSISTANCE GRANT PROGRAM Declaration Process § 204.22 Submitting a request for a fire management assistance.... To ensure that we can process a State's request for a fire management assistance declaration as... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Submitting a request for a...

44 CFR 204.22 - Submitting a request for a fire management assistance declaration.

Code of Federal Regulations, 2012 CFR

2012-10-01

... ASSISTANCE GRANT PROGRAM Declaration Process § 204.22 Submitting a request for a fire management assistance.... To ensure that we can process a State's request for a fire management assistance declaration as... 44 Emergency Management and Assistance 1 2012-10-01 2011-10-01 true Submitting a request for a...

44 CFR 204.22 - Submitting a request for a fire management assistance declaration.

Code of Federal Regulations, 2013 CFR

2013-10-01

... ASSISTANCE GRANT PROGRAM Declaration Process § 204.22 Submitting a request for a fire management assistance.... To ensure that we can process a State's request for a fire management assistance declaration as... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false Submitting a request for a...

44 CFR 204.22 - Submitting a request for a fire management assistance declaration.

Code of Federal Regulations, 2010 CFR

2010-10-01

... ASSISTANCE GRANT PROGRAM Declaration Process § 204.22 Submitting a request for a fire management assistance.... To ensure that we can process a State's request for a fire management assistance declaration as... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Submitting a request for a...

20 CFR 10.536 - What is the penalty for failing to submit a report of dependents?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false What is the penalty for failing to submit a...' COMPENSATION ACT, AS AMENDED Continuing Benefits Reports of Dependents § 10.536 What is the penalty for failing to submit a report of dependents? If an employee fails to submit a requested statement or supporting...

76 FR 13300 - Procedures for Submitting to the Department of Energy Trade Secrets and Commercial or Financial...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-11

... procedures DOE uses to process loan applications submitted to DOE's Advanced Technology Vehicles... procedures DOE uses to process loan applications submitted to DOE's Advanced Technology Vehicles... requirements as described above for any information submitted through the Title XVII loan application process...

20 CFR 416.916 - If you fail to submit medical and other evidence.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false If you fail to submit medical and other... fail to submit medical and other evidence. You (and if you are a child, your parent, guardian, relative... obtain or identify, available medical or other evidence about your impairment(s). When you fail to...

20 CFR 416.916 - If you fail to submit medical and other evidence.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false If you fail to submit medical and other... fail to submit medical and other evidence. You (and if you are a child, your parent, guardian, relative... obtain or identify, available medical or other evidence about your impairment(s). When you fail to...

20 CFR 404.1516 - If you fail to submit medical and other evidence.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false If you fail to submit medical and other evidence. 404.1516 Section 404.1516 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE... fail to submit medical and other evidence. If you do not give us the medical and other evidence that we...

20 CFR 404.1516 - If you fail to submit medical and other evidence.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false If you fail to submit medical and other evidence. 404.1516 Section 404.1516 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE... fail to submit medical and other evidence. If you do not give us the medical and other evidence that we...

20 CFR 404.1516 - If you fail to submit medical and other evidence.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false If you fail to submit medical and other evidence. 404.1516 Section 404.1516 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE... fail to submit medical and other evidence. If you do not give us the medical and other evidence that we...

20 CFR 404.1516 - If you fail to submit medical and other evidence.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false If you fail to submit medical and other evidence. 404.1516 Section 404.1516 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE... fail to submit medical and other evidence. If you do not give us the medical and other evidence that we...

20 CFR 416.916 - If you fail to submit medical and other evidence.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false If you fail to submit medical and other... fail to submit medical and other evidence. You (and if you are a child, your parent, guardian, relative... obtain or identify, available medical or other evidence about your impairment(s). When you fail to...

20 CFR 416.916 - If you fail to submit medical and other evidence.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false If you fail to submit medical and other... fail to submit medical and other evidence. You (and if you are a child, your parent, guardian, relative... obtain or identify, available medical or other evidence about your impairment(s). When you fail to...

20 CFR 416.916 - If you fail to submit medical and other evidence.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false If you fail to submit medical and other... fail to submit medical and other evidence. You (and if you are a child, your parent, guardian, relative... obtain or identify, available medical or other evidence about your impairment(s). When you fail to...

20 CFR 404.1516 - If you fail to submit medical and other evidence.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false If you fail to submit medical and other evidence. 404.1516 Section 404.1516 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE... fail to submit medical and other evidence. If you do not give us the medical and other evidence that we...

45 CFR 286.255 - What quarterly reports must the Tribe submit to us?

Code of Federal Regulations, 2012 CFR

2012-10-01

... 45 Public Welfare 2 2012-10-01 2012-10-01 false What quarterly reports must the Tribe submit to us... must the Tribe submit to us? (a) Quarterly reports. Each Tribe must collect on a monthly basis, and... Data Report: Disaggregated Data—Sections one and two. Each Tribe must file disaggregated information on...

21 CFR 607.20 - Who must register and submit a blood product list.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Who must register and submit a blood product list... BLOOD AND BLOOD PRODUCTS Procedures for Domestic Blood Product Establishments § 607.20 Who must register and submit a blood product list. (a) Owners or operators of all establishments, not exempt under...

21 CFR 607.20 - Who must register and submit a blood product list.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 7 2014-04-01 2014-04-01 false Who must register and submit a blood product list... BLOOD AND BLOOD PRODUCTS Procedures for Domestic Blood Product Establishments § 607.20 Who must register and submit a blood product list. (a) Owners or operators of all establishments, not exempt under...

21 CFR 607.20 - Who must register and submit a blood product list.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 7 2012-04-01 2012-04-01 false Who must register and submit a blood product list... BLOOD AND BLOOD PRODUCTS Procedures for Domestic Blood Product Establishments § 607.20 Who must register and submit a blood product list. (a) Owners or operators of all establishments, not exempt under...

21 CFR 607.20 - Who must register and submit a blood product list.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 7 2013-04-01 2013-04-01 false Who must register and submit a blood product list... BLOOD AND BLOOD PRODUCTS Procedures for Domestic Blood Product Establishments § 607.20 Who must register and submit a blood product list. (a) Owners or operators of all establishments, not exempt under...

21 CFR 607.20 - Who must register and submit a blood product list.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 7 2011-04-01 2010-04-01 true Who must register and submit a blood product list... BLOOD AND BLOOD PRODUCTS Procedures for Domestic Blood Product Establishments § 607.20 Who must register and submit a blood product list. (a) Owners or operators of all establishments, not exempt under...

Medicare program; requirements for providers and suppliers to establish and maintain Medicare enrollment. Final rule.

PubMed

2006-04-21

This final rule requires that all providers and suppliers (other than physicians or practitioners who have elected to "opt-out" of the Medicare program) complete an enrollment form and submit specific information to us. This final rule also requires that all providers and suppliers periodically update and certify the accuracy of their enrollment information to receive and maintain billing privileges in the Medicare program. In addition, this final rule implements provisions in the statute that require us to ensure that all Medicare providers and suppliers are qualified to provide the appropriate health care services. These statutory provisions include requirements meant to protect beneficiaries and the Medicare Trust Funds by preventing unqualified, fraudulent, or excluded providers and suppliers from providing items or services to Medicare beneficiaries or billing the Medicare program or its beneficiaries.

Factors influencing the number of applications submitted per applicant to orthopedic residency programs

PubMed Central

Finkler, Elissa S.; Fogel, Harold A.; Kroin, Ellen; Kliethermes, Stephanie; Wu, Karen; Nystrom, Lukas M.; Schiff, Adam P.

2016-01-01

Background From 2002 to 2014, the orthopedic surgery residency applicant pool increased by 25% while the number of applications submitted per applicant rose by 69%, resulting in an increase of 109% in the number of applications received per program. Objective This study aimed to identify applicant factors associated with an increased number of applications to orthopedic surgery residency programs. Design An anonymous survey was sent to all applicants applying to the orthopedic surgery residency program at Loyola University. Questions were designed to define the number of applications submitted per respondent as well as the strength of their application. Of 733 surveys sent, 140 (19.1%) responses were received. Setting An academic institution in Maywood, IL. Participants Fourth-year medical students applying to the orthopedic surgery residency program at Loyola University. Results An applicant's perception of how competitive he or she was (applicants who rated themselves as ‘average’ submitted more applications than those who rated themselves as either ‘good’ or ‘outstanding’, p=0.001) and the number of away rotations (those who completed >2 away rotations submitted more applications, p=0.03) were significantly associated with an increased number of applications submitted. No other responses were found to be associated with an increased number of applications submitted. Conclusion Less qualified candidates are not applying to significantly more programs than their more qualified counterparts. The increasing number of applications represents a financial strain on the applicant, given the costs required to apply to more programs, and a time burden on individual programs to screen increasing numbers of applicants. In order to stabilize or reverse this alarming trend, orthopedic surgery residency programs should openly disclose admission criteria to prospective candidates, and medical schools should provide additional guidance for candidates in this process

View Submitted Projects | NOAA Gulf Spill Restoration

Science.gov Websites

that have been submitted to the trustees for consideration. To view details of an individual project , click the View icon on the list below or click the project marker on the map. To highlight the location of a project from the list, click the Show on Map icon. All projects that have met the posting

18 CFR 344.2 - Manner of submitting quotations.

Code of Federal Regulations, 2010 CFR

2010-04-01

... quotations. 344.2 Section 344.2 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE INTERSTATE COMMERCE ACT FILING QUOTATIONS FOR U.S. GOVERNMENT SHIPMENTS AT REDUCED RATES § 344.2 Manner of submitting quotations. (a) The quotation or tender...

21 CFR 809.4 - Confidentiality of submitted information.

Code of Federal Regulations, 2011 CFR

2011-04-01

... (CONTINUED) MEDICAL DEVICES IN VITRO DIAGNOSTIC PRODUCTS FOR HUMAN USE General Provisions § 809.4... within the exemption established in § 20.61 of this chapter shall be treated as confidential by the Food... Drug Administration will determine whether information submitted will be treated as confidential in...

21 CFR 809.4 - Confidentiality of submitted information.

Code of Federal Regulations, 2010 CFR

2010-04-01

... (CONTINUED) MEDICAL DEVICES IN VITRO DIAGNOSTIC PRODUCTS FOR HUMAN USE General Provisions § 809.4... within the exemption established in § 20.61 of this chapter shall be treated as confidential by the Food... Drug Administration will determine whether information submitted will be treated as confidential in...

32 CFR 644.360 - Reports submitted for screening.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 4 2011-07-01 2011-07-01 false Reports submitted for screening. 644.360 Section 644.360 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) REAL... to be excess to the particular military department having jurisdiction. The report will contain the...

32 CFR 644.360 - Reports submitted for screening.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 4 2014-07-01 2013-07-01 true Reports submitted for screening. 644.360 Section 644.360 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) REAL... to be excess to the particular military department having jurisdiction. The report will contain the...

32 CFR 644.360 - Reports submitted for screening.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 4 2010-07-01 2010-07-01 true Reports submitted for screening. 644.360 Section 644.360 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) REAL... to be excess to the particular military department having jurisdiction. The report will contain the...

32 CFR 644.360 - Reports submitted for screening.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 4 2013-07-01 2013-07-01 false Reports submitted for screening. 644.360 Section 644.360 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) REAL... to be excess to the particular military department having jurisdiction. The report will contain the...

32 CFR 644.360 - Reports submitted for screening.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 4 2012-07-01 2011-07-01 true Reports submitted for screening. 644.360 Section 644.360 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) REAL... to be excess to the particular military department having jurisdiction. The report will contain the...

40 CFR 86.1605 - Information to be submitted.

Code of Federal Regulations, 2014 CFR

2014-07-01

... (CONTINUED) CONTROL OF EMISSIONS FROM NEW AND IN-USE HIGHWAY VEHICLES AND ENGINES Regulations for Altitude Performance Adjustments for New and In-Use Motor Vehicles and Engines § 86.1605 Information to be submitted... line, model year, engine displacement, engine family, and exhaust emission control systems...

20 CFR 661.430 - Under what conditions may the Governor submit a Workforce Flexibility Plan?

Code of Federal Regulations, 2010 CFR

2010-04-01

... ADMINISTRATION, DEPARTMENT OF LABOR STATEWIDE AND LOCAL GOVERNANCE OF THE WORKFORCE INVESTMENT SYSTEM UNDER TITLE... Plan or may be submitted separately. If it is submitted separately, the workforce flexibility plan must...

40 CFR 60.4375 - What reports must I submit?

Code of Federal Regulations, 2010 CFR

2010-07-01

...). Excess emissions must be reported for all periods of unit operation, including start-up, shutdown, and...), you must submit a written report of the results of each performance test before the close of business...

78 FR 66763 - Information Collection: Oil Spill Financial Responsibility for Offshore Facilities; Submitted for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-06

...] Information Collection: Oil Spill Financial Responsibility for Offshore Facilities; Submitted for OMB Review... information collection request (ICR) concerns the paperwork requirements for 30 CFR 553, Oil Spill Financial... 6, 2013 ADDRESSES: Submit comments on this ICR to the Desk Officer for the Department of the...

30 CFR 210.154 - What documents or other information must I submit for Federal oil valuation purposes?

Code of Federal Regulations, 2010 CFR

2010-07-01

... and Reports-Oil, Gas, and Geothermal Resources § 210.154 What documents or other information must I submit for Federal oil valuation purposes? (a) General. The MMS may require you to submit documents or... submit for Federal oil valuation purposes? 210.154 Section 210.154 Mineral Resources MINERALS MANAGEMENT...

17 CFR 401.2 - Exemption for depository institutions that submit tenders for the account of customers for...

Code of Federal Regulations, 2013 CFR

2013-04-01

... institutions that submit tenders for the account of customers for purchase on original issue of United States... depository institutions that submit tenders for the account of customers for purchase on original issue of... depository institution that submits tenders or subscriptions for purchase on original issue of United States...

17 CFR 401.2 - Exemption for depository institutions that submit tenders for the account of customers for...

Code of Federal Regulations, 2011 CFR

2011-04-01

... institutions that submit tenders for the account of customers for purchase on original issue of United States... depository institutions that submit tenders for the account of customers for purchase on original issue of... depository institution that submits tenders or subscriptions for purchase on original issue of United States...

17 CFR 401.2 - Exemption for depository institutions that submit tenders for the account of customers for...

Code of Federal Regulations, 2014 CFR

2014-04-01

... institutions that submit tenders for the account of customers for purchase on original issue of United States... depository institutions that submit tenders for the account of customers for purchase on original issue of... depository institution that submits tenders or subscriptions for purchase on original issue of United States...

17 CFR 401.2 - Exemption for depository institutions that submit tenders for the account of customers for...

Code of Federal Regulations, 2012 CFR

2012-04-01

... institutions that submit tenders for the account of customers for purchase on original issue of United States... depository institutions that submit tenders for the account of customers for purchase on original issue of... depository institution that submits tenders or subscriptions for purchase on original issue of United States...

17 CFR 401.2 - Exemption for depository institutions that submit tenders for the account of customers for...

Code of Federal Regulations, 2010 CFR

2010-04-01

... institutions that submit tenders for the account of customers for purchase on original issue of United States... depository institutions that submit tenders for the account of customers for purchase on original issue of... depository institution that submits tenders or subscriptions for purchase on original issue of United States...

An analysis of equine round pen training videos posted online: Differences between amateur and professional trainers

PubMed Central

Kydd, Erin; Padalino, Barbara; Henshall, Cathrynne; McGreevy, Paul

2017-01-01

Natural Horsemanship is popular among many amateur and professional trainers and as such, has been the subject of recent scientific enquiry. One method commonly adopted by Natural Horsemanship (NH) trainers is that of round pen training (RPT). RPT sessions are usually split into a series of bouts; each including two phases: chasing/flight and chasing offset/flight offset. However, NH training styles are heterogeneous. This study investigated online videos of RPT to explore the characteristics of RPT sessions and test for differences in techniques and outcomes between amateurs and professionals (the latter being defined as those with accompanying online materials that promote clinics, merchandise or a service to the public). From more than 300 candidate videos, we selected sample files for individual amateur (n = 24) and professional (n = 21) trainers. Inclusion criteria were: training at liberty in a Round Pen; more than one bout and good quality video. Sessions or portions of sessions were excluded if the trainer attached equipment, such as a lunge line, directly to the horse or the horse was saddled, mounted or ridden. The number of bouts and duration of each chasing and non-chasing phase were recorded, and the duration of each RPT session was calculated. General weighted regression analysis revealed that, when compared with amateurs, professionals showed fewer arm movements per bout (p<0.05). Poisson regression analysis showed that professionals spent more time looking up at their horses, when transitioning between gaits, than amateurs did (p<0.05). The probability of horses following the trainer was not significantly associated with amount of chasing, regardless of category. Given that, according to some practitioners, the following response is a goal of RPT, this result may prompt caution in those inclined to give chase. The horses handled by professionals showed fewer conflict behaviours (e.g. kicking, biting, stomping, head-tossing, defecating, bucking and

An analysis of equine round pen training videos posted online: Differences between amateur and professional trainers.

PubMed

Kydd, Erin; Padalino, Barbara; Henshall, Cathrynne; McGreevy, Paul

2017-01-01

Natural Horsemanship is popular among many amateur and professional trainers and as such, has been the subject of recent scientific enquiry. One method commonly adopted by Natural Horsemanship (NH) trainers is that of round pen training (RPT). RPT sessions are usually split into a series of bouts; each including two phases: chasing/flight and chasing offset/flight offset. However, NH training styles are heterogeneous. This study investigated online videos of RPT to explore the characteristics of RPT sessions and test for differences in techniques and outcomes between amateurs and professionals (the latter being defined as those with accompanying online materials that promote clinics, merchandise or a service to the public). From more than 300 candidate videos, we selected sample files for individual amateur (n = 24) and professional (n = 21) trainers. Inclusion criteria were: training at liberty in a Round Pen; more than one bout and good quality video. Sessions or portions of sessions were excluded if the trainer attached equipment, such as a lunge line, directly to the horse or the horse was saddled, mounted or ridden. The number of bouts and duration of each chasing and non-chasing phase were recorded, and the duration of each RPT session was calculated. General weighted regression analysis revealed that, when compared with amateurs, professionals showed fewer arm movements per bout (p<0.05). Poisson regression analysis showed that professionals spent more time looking up at their horses, when transitioning between gaits, than amateurs did (p<0.05). The probability of horses following the trainer was not significantly associated with amount of chasing, regardless of category. Given that, according to some practitioners, the following response is a goal of RPT, this result may prompt caution in those inclined to give chase. The horses handled by professionals showed fewer conflict behaviours (e.g. kicking, biting, stomping, head-tossing, defecating, bucking and

A Comparitive Analysis of the Influence of Weather on the Flight Altitudes of Birds.

NASA Astrophysics Data System (ADS)

Shamoun-Baranes, Judy; van Loon, Emiel; van Gasteren, Hans; van Belle, Jelmer; Bouten, Willem; Buurma, Luit

2006-01-01

Birds pose a serious risk to flight safety worldwide. A Bird Avoidance Model (BAM) is being developed in the Netherlands to reduce the risk of bird aircraft collisions. In order to develop a temporally and spatially dynamic model of bird densities, data are needed on the flight-altitude distribution of birds and how this is influenced by weather. This study focuses on the dynamics of flight altitudes of several species of birds during local flights over land in relation to meteorological conditions.We measured flight altitudes of several species in the southeastern Netherlands using tracking radar during spring and summer 2000. Representatives of different flight strategy groups included four species: a soaring species (buzzard ), an obligatory aerial forager (swift Rpt/SingleRpt?search_topic=all&search_value=Apus+apus&search_kingdom=every&search_span=exactly_for&categories=All&source=html&search_credRating=All" TARGET='itis_window'>Apus apus), a flapping and gliding species (blackheaded gull Rpt/SingleRpt?search_topic=all&search_value=Larus+ridibundus&search_kingdom=every&search_span=exactly_for&categories=All&source=html&search_credRating=All" TARGET='itis_window'>Larus ridibundus), and a flapping species (starling Rpt/SingleRpt?search_topic=all&search_value=Sturnus+vulgaris&search_kingdom=every&search_span=exactly_for&categories=All&source=html&search_credRating=All" TARGET='itis_window'>Sturnus vulgaris).Maximum flight altitudes varied among species, during the day and among days. Weather significantly influenced the flight altitudes of all species studied. Factors such as temperature, relative humidity, atmospheric instability, cloud cover, and sea level pressure were related to flight altitudes. Different combinations of factors explained 40% 70% of the variance in maximum flight altitudes. Weather affected flight

42 CFR 405.809 - Opportunity to submit evidence.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 2 2011-10-01 2011-10-01 false Opportunity to submit evidence. 405.809 Section 405.809 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES MEDICARE PROGRAM FEDERAL HEALTH INSURANCE FOR THE AGED AND DISABLED Appeals Under the Medicare Part B...

43 CFR 3278.10 - When will BLM disclose information I submit under these regulations?

Code of Federal Regulations, 2012 CFR

2012-10-01

... covering public disclosure of data and information contained in Department records. Certain mineral information not protected from disclosure under part 2 may be made available for inspection without a Freedom... information I submit under these regulations? All Federal and Indian data and information submitted to BLM are...

43 CFR 3278.10 - When will BLM disclose information I submit under these regulations?

Code of Federal Regulations, 2013 CFR

2013-10-01

... covering public disclosure of data and information contained in Department records. Certain mineral information not protected from disclosure under part 2 may be made available for inspection without a Freedom... information I submit under these regulations? All Federal and Indian data and information submitted to BLM are...

20 CFR 1002.119 - To whom must the employee submit the application for reemployment?

Code of Federal Regulations, 2010 CFR

2010-04-01

... be submitted to the pre-service employer or to an agent or representative of the employer who has apparent responsibility for receiving employment applications. Depending upon the circumstances, such a... change in ownership of the employer, the application should be submitted to the employer's successor-in...

Web Site Development Support

NASA Technical Reports Server (NTRS)

Abdul, Hameed

2016-01-01

This summer I assisted the RPT Program Office in developing a design plan to update their existing website to current NASA web standards. The finished website is intended for the general public, specifically potential customers interested in learning about NASA's chemical rocket test facility capabilities and test assignment process. The goal of the website is to give the public insight about the purpose and function of the RPT Program. Working on this project gave me the opportunity to learn skills necessary for effective project management. The RPT Program Office manages numerous facilities so they are required to travel often to other sites for meetings throughout the year. Maneuvering around the travel schedule of the office and the workload priority of the IT Department proved to be quite the challenge. I overcame the travel schedule of the office by frequently communicating and checking in with my mentor via email and telephone.

Effectiveness of supplementary irrigant agitation with the Finisher GF Brush on the debridement of oval root canals instrumented with the Gentlefile or nickel titanium rotary instruments.

PubMed

Neelakantan, P; Khan, K; Li, K Y; Shetty, H; Xi, W

2018-07-01

To examine the efficacy of a novel supplementary irrigant agitating brush (Finisher GF Brush, MedicNRG, Kibbutz Afikim, Israel) on the debridement of root canals prepared with a novel stainless steel rotary instrumentation system (Gentlefile; MedicNRG), or nickel titanium rotary instruments in oval root canals. Mandibular premolars (n = 72) were selected and divided randomly into three experimental groups (n = 24) after microCT scanning: group 1, canal preparation to rotary NiTi size 20, .04 taper (R20); group 2, rotary NiTi to size 25, .04 taper (R25) and group 3, Gentlefile size 23, .04 taper (GF). Specimens were subdivided into two subgroups: subgroup A, syringe-and-needle irrigation (SNI); subgroup B, Finisher GF Brush (GB). Ten untreated canals served as controls. Specimens were processed for histological evaluation, and the remaining pulp tissue (RPT) was measured. Data were analysed using Mann-Whitney and Kruskal-Wallis tests (P = 0.05). All experimental groups had significantly less RPT than the control (P < 0.05). Group 3B (GF-GB) had significantly less RPT than groups 1B (R20-GB) and 2B (R25-GF; P < 0.05). When irrigated with SNI, there was no significant difference in the RPT between the three groups (P > 0.05). When instrumented with R20, there was no significant difference between SNI and GF (P < 0.05) whilst GB had significantly less RPT than SNI for R25 (P < 0.05). Supplementary irrigant agitation with the Finisher GF Brush improved the debridement of canals prepared with Gentlefile and size 25, .04 taper rotary NiTi. Root canal debridement did not significantly differ between the instruments when syringe irrigation was used. © 2018 International Endodontic Journal. Published by John Wiley & Sons Ltd.

Cost-Utility of Group Acceptance and Commitment Therapy for Fibromyalgia Versus Recommended Drugs: An Economic Analysis Alongside a 6-Month Randomized Controlled Trial Conducted in Spain (EFFIGACT Study).

PubMed

Luciano, Juan V; D'Amico, Francesco; Feliu-Soler, Albert; McCracken, Lance M; Aguado, Jaume; Peñarrubia-María, María T; Knapp, Martin; Serrano-Blanco, Antoni; García-Campayo, Javier

2017-07-01

The aim of this study was to analyze the cost utility of a group-based form of acceptance and commitment therapy (GACT) in patients with fibromyalgia (FM) compared with patients receiving recommended pharmacological treatment (RPT) or on a waiting list (WL). The data were derived from a previously published study, a randomized controlled trial that focused on clinical outcomes. Health economic outcomes included health-related quality of life and health care use at baseline and at 6-month follow-up using the EuroQoL and the Client Service Receipt Inventory, respectively. Analyses included quality-adjusted life years, direct and indirect cost differences, and incremental cost effectiveness ratios. A total of 156 FM patients were randomized (51 GACT, 52 RPT, 53 WL). GACT was related to significantly less direct costs over the 6-month study period compared with both control arms (GACT €824.2 ± 1,062.7 vs RPT €1,730.7 ± 1,656.8 vs WL €2,462.7 ± 2,822.0). Lower direct costs for GACT compared with RPT were due to lower costs from primary care visits and FM-related medications. The incremental cost effectiveness ratios were dominant in the completers' analysis and remained robust in the sensitivity analyses. In conclusion, acceptance and commitment therapy appears to be a cost-effective treatment compared with RPT in patients with FM. Decision-makers have to prioritize their budget on the treatment option that is the most cost effective for the management of a specific patient group. From government as well as health care perspectives, this study shows that a GACT is more cost effective than pharmacological treatment in management of FM. Copyright © 2017 American Pain Society. Published by Elsevier Inc. All rights reserved.

30 CFR 1210.201 - How do I submit Form ONRR-4430, Solid Minerals Production and Royalty Report?

Code of Federal Regulations, 2014 CFR

2014-07-01

... and submitting Form ONRR-4430 are available on our Internet reporting web site or you may contact us toll free at 1-888-201-6416. (b) When to submit. (1) Unless your lease terms specify a different... submit Form ONRR-4430 electronically using our Internet reporting web site unless you meet the conditions...

30 CFR 1210.201 - How do I submit Form ONRR-4430, Solid Minerals Production and Royalty Report?

Code of Federal Regulations, 2013 CFR

2013-07-01

... and submitting Form ONRR-4430 are available on our Internet reporting web site or you may contact us toll free at 1-888-201-6416. (b) When to submit. (1) Unless your lease terms specify a different... submit Form ONRR-4430 electronically using our Internet reporting web site unless you meet the conditions...

American Indian Policy Review Commission Final Report Submitted to Congress May 17, 1977. Volume One of Two Volumes.

ERIC Educational Resources Information Center

Congress of the U.S. Washington, DC. American Indian Policy Review Commission.

The concepts of sovereignty and trust form the core of the American Indian Policy Review Commission's final report. The commission's responsibility, derived from PL 93-580, was to conduct a comprehensive review of historical/legal developments underlying the Indian/federal government relationship and to recommend necessary policy revisions. After…

20 CFR 410.475 - Failure to submit evidence.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Failure to submit evidence. 410.475 Section 410.475 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL COAL MINE HEALTH AND SAFETY ACT OF 1969, TITLE IV-BLACK LUNG BENEFITS (1969- ) Total Disability or Death Due to Pneumoconiosis § 410.475...

20 CFR 410.475 - Failure to submit evidence.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Failure to submit evidence. 410.475 Section 410.475 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL COAL MINE HEALTH AND SAFETY ACT OF 1969, TITLE IV-BLACK LUNG BENEFITS (1969- ) Total Disability or Death Due to Pneumoconiosis § 410.475...

7 CFR 1776.8 - Methods for submitting applications.

Code of Federal Regulations, 2010 CFR

2010-01-01

... applications may be filed through Grants.gov, the official Federal Government Web site at http://www.grants.gov. The applicant must be registered with Grants.gov before they can submit a grant applicant. The applicant should refer to instructions found on the Grants.gov Web site for procedures for registering and...

7 CFR 1776.8 - Methods for submitting applications.

Code of Federal Regulations, 2012 CFR

2012-01-01

... applications may be filed through Grants.gov, the official Federal Government Web site at http://www.grants.gov. The applicant must be registered with Grants.gov before they can submit a grant applicant. The applicant should refer to instructions found on the Grants.gov Web site for procedures for registering and...

7 CFR 1776.8 - Methods for submitting applications.

Code of Federal Regulations, 2013 CFR

2013-01-01

... applications may be filed through Grants.gov, the official Federal Government Web site at http://www.grants.gov. The applicant must be registered with Grants.gov before they can submit a grant applicant. The applicant should refer to instructions found on the Grants.gov Web site for procedures for registering and...

7 CFR 1776.8 - Methods for submitting applications.

Code of Federal Regulations, 2014 CFR

2014-01-01

... applications may be filed through Grants.gov, the official Federal Government Web site at http://www.grants.gov. The applicant must be registered with Grants.gov before they can submit a grant applicant. The applicant should refer to instructions found on the Grants.gov Web site for procedures for registering and...

7 CFR 1776.8 - Methods for submitting applications.

Code of Federal Regulations, 2011 CFR

2011-01-01

... applications may be filed through Grants.gov, the official Federal Government Web site at http://www.grants.gov. The applicant must be registered with Grants.gov before they can submit a grant applicant. The applicant should refer to instructions found on the Grants.gov Web site for procedures for registering and...

Effect of using reporting guidelines during peer review on quality of final manuscripts submitted to a biomedical journal: masked randomised trial

PubMed Central

Cortés, J; Ribera, J M; Cardellach, F; Selva-O’Callaghan, A; Kostov, B; García, L; Cirugeda, L; Altman, D G; González, J A; Sànchez, J A; Miras, F; Urrutia, A; Fonollosa, V; Rey-Joly, C; Vilardell, M

2011-01-01

Objective To investigate the effect of an additional review based on reporting guidelines such as STROBE and CONSORT on quality of manuscripts. Design Masked randomised trial. Population Original research manuscripts submitted to the Medicina Clínica journal from May 2008 to April 2009 and considered suitable for publication. Intervention Control group: conventional peer reviews alone. Intervention group: conventional review plus an additional review looking for missing items from reporting guidelines. Outcomes Manuscript quality, assessed with a 5 point Likert scale (primary: overall quality; secondary: average quality of specific items in paper). Main analysis compared groups as allocated, after adjustment for baseline factors (analysis of covariance); sensitivity analysis compared groups as reviewed. Adherence to reviewer suggestions assessed with Likert scale. Results Of 126 consecutive papers receiving conventional review, 34 were not suitable for publication. The remaining 92 papers were allocated to receive conventional reviews alone (n=41) or additional reviews (n=51). Four papers assigned to the conventional review group deviated from protocol; they received an additional review based on reporting guidelines. We saw an improvement in manuscript quality in favour of the additional review group (comparison as allocated, 0.25, 95% confidence interval –0.05 to 0.54; as reviewed, 0.33, 0.03 to 0.63). More papers with additional reviews than with conventional reviews alone improved from baseline (22 (43%) v eight (20%), difference 23.6% (3.2% to 44.0%), number needed to treat 4.2 (from 2.3 to 31.2), relative risk 2.21 (1.10 to 4.44)). Authors in the additional review group adhered more to suggestions from conventional reviews than to those from additional reviews (average increase 0.43 Likert points (0.19 to 0.67)). Conclusions Additional reviews based on reporting guidelines improve manuscript quality, although the observed effect was smaller than

41 CFR 105-50.402 - Reports submitted to the Office of Management and Budget.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Office of Management and Budget. 105-50.402 Section 105-50.402 Public Contracts and Property Management... submitted to the Office of Management and Budget. Copies of the foregoing reports will be submitted by the Administrator to the Office of Management and Budget not later than March 30 of each year. ...

77 FR 22602 - Information Collection Activities: Well Control and Production Safety Training, Submitted for...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-16

... Safety Training, Submitted for Office of Management and Budget (OMB) Review; Comment Request ACTION: 60... comments on a collection of information that we will submit to the Office of Management and Budget (OMB... the leasing provisions of the Act related to mineral resources on the OCS. Such rules and regulations...

21 CFR 803.12 - Where and how do I submit reports and additional information?

Code of Federal Regulations, 2010 CFR

2010-04-01

... information? 803.12 Section 803.12 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... I submit reports and additional information? (a) You must submit any written report or additional information required under this part to FDA, CDRH, Medical Device Reporting, P.O. Box 3002, Rockville, MD...

21 CFR 803.12 - Where and how do I submit reports and additional information?

Code of Federal Regulations, 2011 CFR

2011-04-01

... information? 803.12 Section 803.12 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... I submit reports and additional information? (a) You must submit any written report or additional information required under this part to FDA, CDRH, Medical Device Reporting, P.O. Box 3002, Rockville, MD...

21 CFR 803.12 - Where and how do I submit reports and additional information?

Code of Federal Regulations, 2012 CFR

2012-04-01

... information? 803.12 Section 803.12 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... I submit reports and additional information? (a) You must submit any written report or additional information required under this part to FDA, CDRH, Medical Device Reporting, P.O. Box 3002, Rockville, MD...

78 FR 52191 - Information Collection Request Submitted to OMB for Review and Approval; Comment Request...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-22

... Submitted to OMB for Review and Approval; Comment Request; Reformulated Gasoline Commingling Provisions... Protection Agency has submitted an information collection request (ICR), Reformulated Gasoline Commingling...: EPA would like to continue collecting notifications from gasoline retailers and wholesale purchaser...

UFD4 lacking the proteasome-binding region catalyses ubiquitination but is impaired in proteolysis.

PubMed

Xie, Youming; Varshavsky, Alexander

2002-12-01

The ubiquitin system recognizes degradation signals of protein substrates through E3-E2 ubiquitin ligases, which produce a substrate-linked multi-ubiquitin chain. Ubiquitinated substrates are degraded by the 26S proteasome, which consists of the 20S protease and two 19S particles. We previously showed that UBR1 and UFD4, two E3 ligases of the yeast Saccharomyces cerevisiae, interact with specific proteasomal subunits. Here we advance this analysis for UFD4 and show that it interacts with RPT4 and RPT6, two subunits of the 19S particle. The 201-residue amino-terminal region of UFD4 is essential for its binding to RPT4 and RPT6. UFD4(DeltaN), which lacks this N-terminal region, adds ubiquitin to test substrates with apparently wild-type activity, but is impaired in conferring short half-lives on these substrates. We propose that interaction of a targeted substrate with the 26S proteasome involves contacts of specific proteasomal subunits with the substrate-bound ubiquitin ligase, with the substrate-linked multi-ubiquitin chain and with the substrate itself. This multiple-site binding may function to slow down dissociation of the substrate from the proteasome and to facilitate the unfolding of substrate through ATP-dependent movements of the chaperone subunits of the 19S particle.

77 FR 54904 - Notice Inviting Publishers To Submit Tests for a Determination of Suitability for Use in the...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-06

... DEPARTMENT OF EDUCATION Notice Inviting Publishers To Submit Tests for a Determination of... applications: October 1, 2012. SUMMARY: The Secretary of Education (1) invites publishers to submit tests for... the date by which publishers must submit these tests. FOR FURTHER INFORMATION CONTACT: John LeMaster...

78 FR 48152 - Notice Inviting Publishers To Submit Tests for a Determination of Suitability for Use in the...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-07

... DEPARTMENT OF EDUCATION Notice Inviting Publishers To Submit Tests for a Determination of... applications: October 1, 2013. SUMMARY: The Secretary of Education (1) invites publishers to submit tests for... the date by which publishers must submit these tests. FOR FURTHER INFORMATION CONTACT: Michelle Meier...

47 CFR 68.604 - Requirements for submitting technical criteria.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 3 2010-10-01 2010-10-01 false Requirements for submitting technical criteria. 68.604 Section 68.604 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER...) may establish technical criteria for terminal equipment pursuant to ANSI consensus decision-making...

10 CFR 51.41 - Requirement to submit environmental information.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Requirement to submit environmental information. 51.41 Section 51.41 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION REGULATIONS FOR DOMESTIC LICENSING AND RELATED REGULATORY FUNCTIONS National Environmental Policy Act-Regulations...

10 CFR 51.41 - Requirement to submit environmental information.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Requirement to submit environmental information. 51.41 Section 51.41 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) ENVIRONMENTAL PROTECTION REGULATIONS FOR DOMESTIC LICENSING AND RELATED REGULATORY FUNCTIONS National Environmental Policy Act-Regulations...