Microbial diversity and methanogenic activity of Antrim Shale formation waters from recently fractured wells

PubMed Central

Wuchter, Cornelia; Banning, Erin; Mincer, Tracy J.; Drenzek, Nicholas J.; Coolen, Marco J. L.

2013-01-01

The Antrim Shale in the Michigan Basin is one of the most productive shale gas formations in the U.S., but optimal resource recovery strategies must rely on a thorough understanding of the complex biogeochemical, microbial, and physical interdependencies in this and similar systems. We used Illumina MiSeq 16S rDNA sequencing to analyze the diversity and relative abundance of prokaryotic communities present in Antrim shale formation water of three closely spaced recently fractured gas-producing wells. In addition, the well waters were incubated with a suite of fermentative and methanogenic substrates in an effort to stimulate microbial methane generation. The three wells exhibited substantial differences in their community structure that may arise from their different drilling and fracturing histories. Bacterial sequences greatly outnumbered those of archaea and shared highest similarity to previously described cultures of mesophiles and moderate halophiles within the Firmicutes, Bacteroidetes, and δ- and ε-Proteobacteria. The majority of archaeal sequences shared highest sequence similarity to uncultured euryarchaeotal environmental clones. Some sequences closely related to cultured methylotrophic and hydrogenotrophic methanogens were also present in the initial well water. Incubation with methanol and trimethylamine stimulated methylotrophic methanogens and resulted in the largest increase in methane production in the formation waters, while fermentation triggered by the addition of yeast extract and formate indirectly stimulated hydrogenotrophic methanogens. The addition of sterile powdered shale as a complex natural substrate stimulated the rate of methane production without affecting total methane yields. Depletion of methane indicative of anaerobic methane oxidation (AMO) was observed over the course of incubation with some substrates. This process could constitute a substantial loss of methane in the shale formation. PMID:24367357

Recent Results from KLOE-2

NASA Astrophysics Data System (ADS)

Krzemien, Wojciech

The most recent results from the KLOE experiment are presented, covering: the measurement of the running fine-structure constant αem, the Dalitz plot measurement of η → π+π‑π0, the search of a U boson, tests of discrete symmetries and quantum coherence. The KLOE-2 Collaboration will take data until mid 2018 aiming to collect 5 fb1 increasing the data set, in order to produce new precision measurements and continue studies of fundamental symmetries and New Physics.

Recent Results from PHOBOS at Rhic

NASA Astrophysics Data System (ADS)

Garcia, Edmundo; Back, B. B.; Baker, M. D.; Ballintijn, M.; Barton, D. S.; Betts, R. R.; Bickley, A. A.; Bindel, R.; Busza, W.; Carroll, A.; Chai, Z.; Decowski, M. P.; Garcia, E.; Gburek, T.; George, N.; Gulbrandsen, K.; Halliwell, C.; Hamblen, J.; Hauer, M.; Henderson, C.; Hofman, D. J.; Hollis, R. S.; Hołyński, R.; Holzman, B.; Iordanova, A.; Johnson, E.; Kane, J. L.; Khan, N.; Kulinich, P.; Kuo, C. M.; Lin, W. T.; Manly, S.; Mignerey, A. C.; Nouicer, R.; Olszewski, A.; Pak, R.; Reed, C.; Roland, C.; Roland, G.; Sagerer, J.; Seals, H.; Sedykh, I.; Smith, C. E.; Stankiewicz, M. A.; Steinberg, P.; Stephans, G. S. F.; Sukhanov, A.; Tonjes, M. B.; Trzupek, A.; Vale, C.; van Nieuwenhuizen, G. J.; Vaurynovich, S. S.; Verdier, R.; Veres, G. I.; Wenger, E.; Wolfs, F. L. H.; Wosiek, B.; Woźniak, K.; Wysłouch, B.

The PHOBOS detector is one of four heavy-ion experiments at the Relativistic Heavy Ion Collider (RHIC) at Brookhaven National Laboratory. In this paper we will review some of the results of PHOBOS from the data collected in p+p, d+Au and Au+Au collisions at nucleon-nucleon center-of-mass energies up to 200 GeV. In the most central Au+Au collisions at the highest energy, evidence is found for the formation of a very high energy density and highly interactive system, which can not be described in terms of hadrons, and which has a relatively low baryon density.

Review of Recent BABAR Results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lista, L.

2004-12-02

We present a review of recent results from BaBar experiment. BaBar detector has collected about 256 millions of B{bar B} events at PEP-II, the asymmetric e{sup +}e{sup -} collider located at SLAC running at the {Upsilon}(4S) resonance. We have studied CP violation in B mesons, observing the first evidence of direct CP violation in B meson decays and measured CP asymmetries relevant for the determination of the angles of the CKM Unitarity Triangle. BaBar physics program covers many other topics, including measurements of CKM matrix elements, charm physics, and search for new physics processes.

Recent Stirling engine loss-understanding results

NASA Technical Reports Server (NTRS)

Tew, Roy C.; Thieme, Lanny G.; Dudenhoefer, James E.

1990-01-01

For several years, NASA and other U.S. government agencies have been funding experimental and analytical efforts to improve the understanding of Stirling thermodynamic losses. NASA's objective is to improve Stirling engine design capability to support the development of new engines for space power. An overview of these efforts was last given at the 1988 IECEC. Recent results of this research are reviewed.

Recent Opportunity Microscopic Imager Results

NASA Astrophysics Data System (ADS)

Herkenhoff, K. E.; Arvidson, R. E.; Jolliff, B. L.; Yingst, R.; Team, A.

2013-12-01

Opportunity. The extremely soft bedrock exposed at a Whitewater Lake outcrop target dubbed 'Azilda' is mostly fine-grained, with dispersed 2-5 mm-diameter spherules and resistant veins. This target was easily abraded by the RAT, exposing a sandstone-like texture, but the sorting of grains is difficult to determine at MI resolution. Darker, erosion-resistant veneers, similar to desert varnishes on Earth, appear to record aqueous alteration that post-dates the formation of the Ca sulfate veins; they likely contain the nontronite that is observed by CRISM in this area. The inferred neutral pH and relatively low temperature of the fluids involved in these phases of alteration would have provided a habitable environment for life if it existed on Mars at that time. Because Opportunity can no longer directly sense phyllosilicate mineralogy with the MiniTES or Mössbauer spectrometers, it is focusing on characterizing the chemistry with the APXS and texture with the MI of potential phyllosilicate host rocks. The Athena MI continues to return useful images of Mars that are being used to study the textures of rocks and soils at Endeavour crater. Exploration by Opportunity continues, with the rover approaching 'Solander Point' and more exposures of phyllosilicates detected from orbit; the latest MI results will be presented at the conference.

Recent BESII Results of Charmonium Decays

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mo, X. H.

2006-02-11

Using 14 million {psi}' data sample collected with BES at BEPC, the recent results relevant to {chi}cJ states are presented, which include measurement of {chi}cJ resonance parameters, study of {chi}cJ {yields} VV and K{sub S}{sup 0}K{sub S}{sup 0} contained final state, and partial wave analysis of {chi}c0 {yields} {pi}+{pi}-K+K-.

Synapse formation and plasticity: recent insights from the perspective of the ubiquitin proteasome system.

PubMed

Patrick, Gentry N

2006-02-01

The formation of synaptic connections during the development of the nervous system requires the precise targeting of presynaptic and postsynaptic compartments. Furthermore, synapses are continually modified in the brain by experience. Recently, the ubiquitin proteasome system has emerged as a key regulator of synaptic development and function. The modification of proteins by ubiquitin, and in many cases their subsequent proteasomal degradation, has proven to be an important mechanism to control protein stability, activity and localization at synapses. Recent work has highlighted key questions of the UPS during the development and remodeling of synaptic connections in the nervous system.

Most Recent Sampling Results for Annex III Building

EPA Pesticide Factsheets

Contains email from Scott Miller, US EPA to Scott Kramer. Subject: Most Recent Sampling Results for Annex III Building. (2:52 PM) and Gore(TM) Surveys Analytical Results U.S. Geological Survey, Montgomery, AL.

Recent Results from Borexino

NASA Astrophysics Data System (ADS)

Jeschke, D.; Agostini, M.; Altenmüller, K.; Appel, S.; Atroshchenko, V.; Bellini, G.; Benziger, J.; Bick, D.; Bonfini, G.; Bravo, D.; Caccianiga, B.; Calaprice, F.; Caminata, A.; Carlini, M.; Cavalcante, P.; Chepurnov, A.; Choi, K.; D'Angelo, D.; Davini, S.; Derbin, A.; Di Noto, L.; Drachnev, I.; Etenko, A.; Fomenko, K.; Franco, D.; Gabriele, F.; Galbiati, C.; Ghiano, C.; Giammarchi, M.; Goeger-Neff, M.; Goretti, A.; Gromov, M.; Hagner, C.; Hungerford, E.; Ianni, Aldo; Ianni, Andrea; Jany, A.; Jedrzejczak, K.; Jeschke, D.; Kobychev, V.; Korablev, D.; Korga, G.; Kryn, D.; Laubenstein, M.; Lehnert, B.; Litvinovich, E.; Lombardi, F.; Lombardi, P.; Ludhova, L.; Lukyanchenko, G.; Machulin, I.; Manecki, S.; Maneschg, W.; Manuzio, G.; Marcocci, S.; Meroni, E.; Meyer, M.; Miramonti, L.; Misiaszek, M.; Montuschi, M.; Mosteiro, P.; Muratova, V.; Neumair, B.; Oberauer, L.; Obolensky, M.; Ortica, F.; Pallavicini, M.; Papp, L.; Pocar, A.; Ranucci, G.; Razeto, A.; Re, A.; Romani, A.; Roncin, R.; Rossi, N.; Schönert, S.; Semenov, D.; Skorokhvatov, M.; Smirnov, O.; Sotnikov, A.; Sukhotin, S.; Suvorov, Y.; Tartaglia, R.; Testera, G.; Thurn, J.; Toropova, M.; Unzhakov, E.; Vishneva, A.; Vogelaar, R. B.; von Feilitzsch, F.; Wang, H.; Weinz, S.; Winter, J.; Wojcik, M.; Wurm, M.; Yokley, Z.; Zaimidoroga, O.; Zavatarelli, S.; Zuber, K.; Zuzel, G.

2017-01-01

The Borexino experiment is taking data since 2007 at the Laboratori Nazionali del Gran Sasso in Italy accomplishing outstanding achievements in the field of neutrino physics. Its success is strongly based on the unprecedented ultra-high radio-purity of the inner scintillator core. The main features of the detector and the impressive results for solar and geo-neutrinos obtained by Borexino so far are summarized. The main focus is laid on the most recent results, i.e. the first real-time measurement of the solar pp neutrino flux and the detection of the signal induced by geo-neutrinos with a significance as high as 5.9σ. The measurement of the pp neutrino flux represents a direct probe of the major mechanism of energy production in the Sun and its observation at a significance of 10σ proves the stability of the Sun over a time of at least 105 years. It further puts Borexino in the unique position of being capable to test the MSW-LMA paradigm across the whole solar energy range. The geo-neutrino data allow to infer information concerning important geophysical properties of the Earth that are also discussed. The perspectives of the final stage of the Borexino solar neutrino program that are centered on the goal of measuring the CNO neutrinos that so far escaped any observation are outlined.

The Wide-Field Imaging Interferometry Testbed: Recent Results

NASA Technical Reports Server (NTRS)

Rinehart, Stephen

2006-01-01

We present recent results from the Wide-Field Imaging Interferometry Testbed (WIIT). The data acquired with the WIIT is "double Fourier" data, including both spatial and spectral information within each data cube. We have been working with this data, and starting to develop algorithms, implementations, and techniques for reducing this data. Such algorithms and tools are of great importance for a number of proposed future missions, including the Space Infrared Interferometric Telescope (SPIRIT), the Submillimeter Probe of the Evolution of Cosmic Structure (SPECS), and the Terrestrial Planet Finder Interferometer (TPF-I)/Darwin. Recent results are discussed and future study directions are described.

Recent results of the LOPES experiment

NASA Astrophysics Data System (ADS)

Haungs, A.; Apel, W. D.; Arteaga, J. C.; Asch, T.; Badea, F.; Bähren, L.; Bekk, K.; Bertaina, M.; Biermann, P. L.; Blümer, J.; Bozdog, H.; Brancus, I. M.; Brüggemann, M.; Buchholz, P.; Buitink, S.; Cantoni, E.; Chiavassa, A.; Cossavella, F.; Daumiller, K.; de Souza, V.; di Pierro, F.; Doll, P.; Ender, M.; Engel, R.; Falcke, H.; Finger, M.; Fuhrmann, D.; Gemmeke, H.; Ghia, P. L.; Glasstetter, R.; Grupen, C.; Heck, D.; Hörandel, J. R.; Horneffer, A.; Huege, T.; Isar, P. G.; Kampert, K.-H.; Kang, D.; Kickelbick, D.; Kolotaev, Y.; Krömer, O.; Kuijpers, J.; Lafebre, S.; Link, K.; Łuczak, P.; Ludwig, M.; Mathes, H. J.; Mayer, H. J.; Melissas, M.; Mitrica, B.; Morello, C.; Navarra, G.; Nehls, S.; Nigl, A.; Oehlschläger, J.; Over, S.; Palmieri, N.; Petcu, M.; Pierog, T.; Rautenberg, J.; Rebel, H.; Roth, M.; Saftoiu, A.; Schieler, H.; Schmidt, A.; Schröder, F.; Sima, O.; Singh, K.; Toma, G.; Trinchero, G.; Ulrich, H.; Walkowiak, W.; Weindl, A.; Wochele, J.; Wommer, M.; Zabierowski, J.; Zensus, J. A.; Lopes Collaboration

2009-12-01

LOPES measures radio pulses from extensive air showers and aims to calibrate the emitted signal in the primary energy range of 10 16-10 18 eV. LOPES, a digital radio interferometer using high bandwidths and fast data processing, is set up at the location of the KASCADE-Grande extensive air shower experiment in Karlsruhe, Germany and profits from the reconstructed air shower observables of KASCADE-Grande. We report about recent analysis results of the radio signals measured by LOPES.

Recent work and results on sparrow project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harvey, Neal R

2010-12-23

This briefing describes recent work undertaken on the Sparrow Project and results of this work. It describes experiments comparing the use of Genie with 2 classes with 3 classes for the problem of ship delineation. It also describes some preliminary work in the area of the optimization of segmentation techniques.

Electron-cloud updated simulation results for the PSR, and recent results for the SNS

NASA Astrophysics Data System (ADS)

Pivi, M.; Furman, M. A.

2002-05-01

Recent simulation results for the main features of the electron cloud in the storage ring of the Spallation Neutron Source (SNS) at Oak Ridge, and updated results for the Proton Storage Ring (PSR) at Los Alamos are presented in this paper. A refined model for the secondary emission process including the so called true secondary, rediffused and backscattered electrons has recently been included in the electron-cloud code.

Recent results in nucleocosmochronology

NASA Astrophysics Data System (ADS)

Cowan, John J.; Thielemann, F.-K.; Truran, J. W.

Rates for beta-delayed neutron emission and fission have recently been calculated for the mass range 70-100. Using these new rates and the calculated rates for neutron capture, photodisintegration and beta decay, dynamical r-process calculations have been performed. For certain assumed conditions, these r-process calculations give a good fit to the solar system r-process abundance curve. These calculations have been used to obtain new production ratios for the nuclear chronometer pairs used to determine the age of the Galaxy - (Th-232)/(U-238) = 1.60, (U-235)/(U-238) = 1.16, and (Pu-244)/(U-238) = 0.40. Using the new production ratio for (Th-232)/(U-238) and (U-235)/(U238), with the observed meteoritic values for these nuclei and assuming a model of chemical evolution of the Galaxy, the age of the Galaxy has been determined. The results depend upon the initial nucleosynthesis enrichment in the Galactic disk, S0. While there are uncertainties in the calculations for a range of S0 from 0.1 to 0.3 (i.e., from 10 to 30 percent), the age of the Galaxy is found to be 12.4-14.7 Gyr.

GRB 980425 host: [C II], [O I], and CO lines reveal recent enhancement of star formation due to atomic gas inflow

NASA Astrophysics Data System (ADS)

Michałowski, M. J.; Castro Cerón, J. M.; Wardlow, J. L.; Karska, A.; Messias, H.; van der Werf, P.; Hunt, L. K.; Baes, M.; Castro-Tirado, A. J.; Gentile, G.; Hjorth, J.; Le Floc'h, E.; Pérez-Martínez, R.; Nicuesa Guelbenzu, A.; Rasmussen, J.; Rizzo, J. R.; Rossi, A.; Sánchez-Portal, M.; Schady, P.; Sollerman, J.; Xu, D.

2016-11-01

Context. Accretion of gas from the intergalactic medium is required to fuel star formation in galaxies. We have recently suggested that this process can be studied using host galaxies of gamma-ray bursts (GRBs). Aims: Our aim is to test this possibility by studying in detail the properties of gas in the closest galaxy hosting a GRB (980425). Methods: We obtained the first ever far-infrared (FIR) line observations of a GRB host, namely Herschel/PACS resolved [C II] 158 μm and [O I] 63 μm spectroscopy, and an APEX/SHeFI CO(2-1) line detection and ALMA CO(1-0) observations of the GRB 980425 host. Results: The GRB 980425 host has elevated [C II]/FIR and [O I]/FIR ratios and higher values of star formation rates (SFR) derived from line ([C II], [O I], Hα) than from continuum (UV, IR, radio) indicators. [C II] emission exhibits a normal morphology, peaking at the galaxy centre, whereas [O I] is concentrated close to the GRB position and the nearby Wolf-Rayet region. The high [O I] flux indicates that there is high radiation field and high gas density at these positions, as derived from modelling of photo-dissociation regions. The [C II]/CO luminosity ratio of the GRB 980425 host is close to the highest values found for local star-forming galaxies. Indeed, its CO-derived molecular gas mass is low given its SFR and metallicity, but the [C II]-derived molecular gas mass is close to the expected value. Conclusions: The [O I] and H I concentrations and the high radiation field and density close to the GRB position are consistent with the hypothesis of a very recent (at most a few tens of Myr ago) inflow of atomic gas triggering star formation. In this scenario dust has not had time to build up (explaining high line-to-continuum ratios). Such a recent enhancement of star formation activity would indeed manifest itself in high SFRline/SFRcontinuum ratios because the line indicators are sensitive only to recent (≲10 Myr) activity, whereas the continuum indicators measure

Recent Results from NASA's Morphing Project

NASA Technical Reports Server (NTRS)

McGowan, Anna-Maria R.; Washburn, Anthony E.; Horta, Lucas G.; Bryant, Robert G.; Cox, David E.; Siochi, Emilie J.; Padula, Sharon L.; Holloway, Nancy M.

2002-01-01

The NASA Morphing Project seeks to develop and assess advanced technologies and integrated component concepts to enable efficient, multi-point adaptability in air and space vehicles. In the context of the project, the word "morphing" is defined as "efficient, multi-point adaptability" and may include macro, micro, structural and/or fluidic approaches. The project includes research on smart materials, adaptive structures, micro flow control, biomimetic concepts, optimization and controls. This paper presents an updated overview of the content of the Morphing Project including highlights of recent research results.

The recent formation of Saturn's moonlets from viscous spreading of the main rings.

PubMed

Charnoz, Sébastien; Salmon, Julien; Crida, Aurélien

2010-06-10

The regular satellites of the giant planets are believed to have finished their accretion concurrent with the planets, about 4.5 Gyr ago. A population of Saturn's small moons orbiting just outside the main rings are dynamically young (less than 10(7) yr old), which is inconsistent with the formation timescale for the regular satellites. They are also underdense ( approximately 600 kg m(-3)) and show spectral characteristics similar to those of the main rings. It has been suggested that they accreted at the rings' edge, but hitherto it has been impossible to model the formation process fully owing to a lack of computational power. Here we report a hybrid simulation in which the viscous spreading of Saturn's rings beyond the Roche limit (the distance beyond which the rings are gravitationally unstable) gives rise to the small moons. The moonlets' mass distribution and orbital architecture are reproduced. The current confinement of the main rings and the existence of the dusty F ring are shown to be direct consequences of the coupling of viscous evolution and satellite formation. Saturn's rings, like a mini protoplanetary disk, may be the last place where accretion was recently active in the Solar System, some 10(6)-10(7) yr ago.

Salt dissolution and sinkhole formation: Results of laboratory experiments

NASA Astrophysics Data System (ADS)

Oz, Imri; Eyal, Shalev; Yoseph, Yechieli; Ittai, Gavrieli; Elad, Levanon; Haim, Gvirtzman

2016-10-01

The accepted mechanism for the formation of thousands of sinkholes along the coast of the Dead Sea suggests that their primary cause is dissolution of a salt layer by groundwater undersaturated with respect to halite. This is related to the drop in the Dead Sea level, which caused a corresponding drop of the freshwater-saltwater interface, resulting in fresher groundwater replacing the brines that were in contact with the salt layer. In this study we used physical laboratory experiments to examine the validity of this mechanism by reproducing the full dynamic natural process and to examine the impact of different hydrogeological characteristics on this process. The experimental results show surface subsidence and sinkhole formation. The stratigraphic configurations of the aquifer, together with the mechanical properties of the salt layer, determine the dynamic patterns of the sinkhole formation (instantaneous versus gradual formation). Laboratory experiments were also used to study the potential impact of future stratification in the Dead Sea, if and when the "Red Sea-Dead Sea Canal" project is carried out, and the Dead Sea level remains stable. The results show that the dissolution rates are slower by 1 order of magnitude in comparison with a nonstratified saltwater body, and therefore, the processes of salt dissolution and sinkhole formation will be relatively restrained under these conditions.

Gas potential of the Rome Trough in Kentucky: Results of recent Cambrian exploration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harris, D.C.; Drahovzal, J.A.

1996-09-01

A recent gas discovery in the Rome Trough suggests the need to re-evaluate the deep Cambrian potential of eastern Kentucky. A new phase of Cambrian exploration began in mid-1994 with a new pool discovery by the Carson Associates No. 1 Kazee well in Elliott County, Ky. This well blew out and initially flowed 11 MMcfd of gas from the upper Conasauga Group/Rome Formation at 6,258 to 6,270 feet. After this discovery, a second exploratory well (the Blue Ridge No. 1Greene) was drilled on a separate structure in Elliott County in late 1995. The Blue Ridge well was temporarily abandoned, butmore » had shows of gas and condensate. In early 1996, Carson Associates offset their initial discovery well with the No. 33 Lawson Heirs well. This activity follows a frustrating exploration history in the Rome Trough that is marked by numerous gas and oil shows, but rare commercial production. Only three single-well pools have produced commercial gas from the trough, including the recent Kazee well. Stratigraphic units below the Cambrian-Ordovician Knox Group in the Rome Trough are dramatically thicker than their equivalents on the shelf to the north. The interval in the trough is thought to include rocks as old as Early Cambrian, consisting of a basal sandstone, equivalents of the Shady/Tomstown Dolomite, the Rome Formation, and the Conasauga Formation. Sandstones and fractured shales have been responsible for most of the production to date, but dolostone intervals may also have potential. Limited seismic data indicate possible fan-delta and basin-floor fan deposits that may have reservoir potential.« less

Paleomagnetism of the Todos Santos Formation in the Maya Block, Chiapas, Mexico: Preliminary Results

NASA Astrophysics Data System (ADS)

Godinez-Urban, A.; Molina-Garza, R. S.; Iriondo, A.; Geissman, J. W.

2008-12-01

Preliminary results of a paleomagnetic study on jurassic volcanic rocks (U-Pb 188.8 +/- 3.2Ma) locally interbedded with red beds assigned to the Todos Santos Formation, sampled in the Homoclinal Tectonic Province of the Neogene Fold Belt, Chiapas-Mexico, reveal multi component magnetizations acquired during pre- and post- folding of these rocks. The samples responded well to thermal demagnetization, but not so to AF demagnetization, suggesting that a high coercivity mineral phase like hematite is the main remanence carrier. The post-folding B-component direction of Dec=174.3 Inc=-30.6 (k=46; alpha95=13.6; N=4) represents a recent Tertiary? overprint; while the pre-folding C-component direction of Dec=329.9 Inc=7.8 (k=12.5; alpha95=16.3; N=8) is in agreement with a previously reported small data set for the Todos Santos Formation. When compared to the North American reference direction (Jurassic Kayenta Formation) the observed direction indicates a counterclockwise rotation of 35.9 +/- 16.6 degrees, and moderate north to south latitudinal displacement. If a reference pole from NE North America is used, the amount of counterclockwise rotation and latitudinal displacement are both slightly reduced. If the assumption that Jurassic strata in Chiapas reflect displacement of the Maya Block, then these data are consistent with reconstructions of the Maya Block in the Gulf of Mexico region. Other sites sampled in Jurassic strata suggest that in addition to the interpreted regional rotation, local (vertical-axis) rotations may have affected the region in more recent times.

Recent results from TRISTAN at KEK

DOE Office of Scientific and Technical Information (OSTI.GOV)

Suzuki, Shiro

1994-12-01

Recent results of the TRISTAN experiment with high luminosity runs are reviewed. Updated results on lepton and quark pair production in the annihilation processes are presented, and limits on the compositeness scale and lower mass limit for extra Z bosons are given. The total hadronic cross section is presented in the effective Born approximation. A search for a resonance suggested by the L3 group is done in several different final states. The strong coupling constant {alpha}{sub s} is derived from several observables with an improved theoretical framework. The running nature of {alpha}{sub s} is studied in comparison with PEP4 andmore » ALEPH data. Various properties of quark and gluon jets are examined. Hard scattering of two photons is established and these data provide information on quark and gluon distributions in the photon.« less

Recent results on CVD diamond radiation sensors

NASA Astrophysics Data System (ADS)

Weilhammer, P.; Adam, W.; Bauer, C.; Berdermann, E.; Bogani, F.; Borchi, E.; Bruzzi, M.; Colledani, C.; Conway, J.; Dabrowski, W.; Delpierre, P.; Deneuville, A.; Dulinski, W.; v. d. Eijk, R.; van Eijk, B.; Fallou, A.; Fish, D.; Fried, M.; Gan, K. K.; Gheeraert, E.; Grigoriev, E.; Hallewell, G.; Hall-Wilton, R.; Han, S.; Hartjes, F.; Hrubec, J.; Husson, D.; Kagan, H.; Kania, D.; Kaplon, J.; Kass, R.; Knopfle, K. T.; Krammer, M.; Manfredi, P. F.; Meier, D.; LeNormand; Pan, L. S.; Pernegger, H.; Pernicka, M.; Plano, R.; Re, V.; Riester, J. L.; Roe, S.; Roff; Rudge, A.; Schieber, M.; Schnetzer, S.; Sciortino, S.; Speziali, V.; Stelzer, H.; Stone, R.; Tapper, R. J.; Tesarek, R.; Thomson, G. B.; Trawick, M.; Trischuk, W.; Turchetta, R.; RD 42 Collaboration

1998-02-01

CVD diamond radiation sensors are being developed for possible use in trackers in the LHC experiments. The diamond promises to be radiation hard well beyond particle fluences that can be tolerated by Si sensors. Recent results from the RD 42 collaboration on charge collection distance and on radiation hardness of CVD diamond samples will be reported. Measurements with diamond tracking devices, both strip detectors and pixel detectors, will be discussed. Results from beam tests using a diamond strip detector which was read out with fast, 25 ns shaping time, radiation-hard pipeline electronics will be presented.

On the correlation between the recent star formation rate in the Solar Neighbourhood and the glaciation period record on Earth

NASA Astrophysics Data System (ADS)

de la Fuente Marcos, R.; de la Fuente Marcos, C.

2004-11-01

Shaviv [New Astron. 8 (2003) 39; J. Geophys. Res. 108 (2003) 3] has shown evidence for a correlation between variations in the Galactic cosmic ray flux reaching Earth and the glaciation period record on Earth during the last 2 Gyr. If the flux of cosmic rays is mainly the result of Type II supernovae, an additional correlation between the star formation history of the Solar Neighbourhood and the timing of past ice ages is expected. Higher star formation rate implies increased cosmic ray flux and this may translate into colder climate through a rise in the average low altitude cloud cover. Here we reanalyze the correlation between this star formation history and the glaciation period record on Earth using a volume limited open cluster sample. Numerical modeling and recent observational data indicate that the correlation is rather strong but only if open clusters within 1.5 kpc from the Sun are considered. Under this constraint, our statistical analysis not only suggests a strong correlation in the timing of the events (enhanced star formation and glaciation episodes), but also in the severity and length of the episodes. In particular, the snowball Earth scenario appears to be connected with the strongest episode of enhanced star formation recorded in the Solar Neighbourhood during the last 2 Gyr.

Recent Heating and Current Drive results on JET

NASA Astrophysics Data System (ADS)

Tuccillo, A. A.; Baranov, Y.; Barbato, E.; Bibet, Ph.; Castaldo, C.; Cesario, R.; Cocilovo, V.; Crisanti, F.; De Angelis, R.; Ekedahl, A. C.; Figueiredo, A.; Graham, M.; Granucci, G.; Hartmann, D.; Heikkinen, J.; Hellsten, T.; Imbeaux, F.; Jones, T. T. H.; Johnson, T.; Kirov, K. V.; Lamalle, P.; Laxaback, M.; Leuterer, F.; Litaudon, X.; Maget, P.; Mailloux, J.; Mantsinen, M. J.; Mayoral, M. L.; Meo, F.; Monakhov, I.; Nguyen, F.; Noterdaeme, J.-M.; Pericoli-Ridolfini, V.; Podda, S.; Panaccione, L.; Righi, E.; Rimini, F.; Sarazin, Y.; Sibley, A.; Staebler, A.; Tala, T.; Van Eester, D.

2001-10-01

An overview is presented of the results obtained on JET by the Heating and Current Drive Task Force (TF-H) in the period May 2000—March 2001. A strongly improved Lower Hybrid (LH) coupling was achieved by optimizing the plasma shape and by controlling the local edge density via the injection of CD4. Up to 4 MW have been coupled in type III ELMy H-mode and/or on Internal Transport Barrier (ITB) plasmas with reflection coefficients as low as 4%. Long lasting quasi steady-state ITBs have been obtained by adding the LH current to the bootstrap and beam driven components. Furthermore the use of LH in the pre-heat phase results in electron temperature in excess of 10 keV, deep negative magnetic shear and strongly reduced power threshold for ITB formation. Preliminary results on ICRF coupling are reported including the effect of CD4 injection and the commissioning of the wide band matching system on ELMy plasmas. IC CD scenarios have been studied in H and 3He minority and used to modify the stability of the sawtooth to influence the formation of seed islands for the appearance of NTM. Up to 3 MW of IC power was coupled in the high magnetic field fast wave CD scenario. Preliminary MSE measurements indicate differences in the current profiles between -90° and +90° phasing. Careful measurements of the toroidal rotation, in plasmas heated by ICRF only show some dependence on the position of the resonance layer. Finally the use of ICRF minority heating under real-time control, in response to measured plasma parameters to simulate the effect of alpha particles, is presented. ICRF heating results in ITER non-activated scenarios are reported in a companion paper.

Initial Satellite Formation Flight Results from the Magnetospheric Multiscale Mission

NASA Technical Reports Server (NTRS)

Williams, Trevor; Ottenstein, Neil; Palmer, Eric; Farahmand, Mitra

2016-01-01

This paper describes the underlying dynamics of formation flying in a high-eccentricity orbit such as that of the Magnetospheric Multiscale mission. The GPS-based results used for MMS navigation is summarized, as well as the procedures that are used to design the maneuvers used to place the spacecraft into a tetrahedron formation and then maintain it. The details of how to carry out these maneuvers are then discussed. Finally, the numerical results that have been obtained concerning formation flying for the MMS mission to date (e.g. tetrahedron sizes flown, maneuver execution error, fuel usage, etc.) are presented in detail.

Recent Results from ISOLDE and HIE-ISOLDE

NASA Astrophysics Data System (ADS)

Borge, María J. G.

2018-02-01

ISOLDE is the CERN facility dedicated to the production of rare ion beams for many different experiments in the fields of nuclear and atomic physics, materials science and life sciences. The HIE-ISOLDE, Higher Intensity and Energy upgrade has finished its stage 1 dedicated to upgrade the energy up to 5.5 MeV/u, producing the first radioactive beams with this energy in September 9th 2016. Recent results from the low energy and post-accelerated beams are given in this contribution.

Recent Aspects on the Effect of Inclusion Characteristics on the Intragranular Ferrite Formation in Low Alloy Steels: A Review

NASA Astrophysics Data System (ADS)

Mu, Wangzhong; Jönsson, Pär Göran; Nakajima, Keiji

2017-04-01

Intragranular ferrite (IGF), which nucleates from specific inclusion surfaces in low alloy steels, is the desired microstructure to improve mechanical properties of steel such as the toughness. This microstructure is especially important in the coarse grain heat affected zone (CGHAZ) of weldments. The latest review paper focusing on the role of non-metallic inclusions in the IGF formation in steels has been reported by Sarma et al. in 2009 (ISIJ int., 49(2009), 1063-1074). In recent years, large amount of papers have been presented to investigate different issues of this topic. This paper mainly highlights the frontiers of experimental and theoretical investigations on the effects of inclusion characteristics, such as the composition, size distribution and number density, on the IGF formation in low carbon low-alloyed steels, undertaken by the group of Applied Process Metallurgy, KTH Royal Institute of Technology. Related results reported in previous studies are also introduced. Also, plausible future work regarding various items of IGF formation is mentioned in each section. This work aims to give a better control of improving the steel quality during casting and in the heat affected zone (HAZ) of weldment, according to the concept of oxide metallurgy.

Recent Results from Experiments at COSY

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goldenbaum, Frank

2010-08-05

In hadron physics, experiments using hadronic probes may shed light on open questions on the structure of hadrons, their interactions that are subject to the strong force and on the symmetries of nature. Therefore a major focus of the physics program studied at the COoler SYnchrotron COSY of the Forschungszentrum Juelich is the production of mesons and hyperons in hadron- hadron scattering with the aim to investigate relevant production processes, interactions of the participating particles as well as symmetries and symmetry breaking. The COoler SYnchrotron COSY at Juelich accelerates protons and deuterons with momenta up to 3.7 GeV/c covering hadronmore » physics in the light quark sector. The availability of the beam cooling systems allow precision measurements, using polarized proton and deuteron beams in combination with polarized Hydrogen or Deuterium targets. Due to the excellent experimental conditions at COSY single- and double-polarization measurements can be performed with high reaction rates. With the operation of the recently installed WASA-at-COSY apparatus, high-statistics studies aiming at rare decays of {eta} and {eta}{sup '} are effectively turning COSY into a meson factory. This contribution summarizes the ongoing physics program at the COSY facility, using the detector systems ANKE, WASA and COSY-TOF highlighting a few selective recent results and outlining future developments. The research at COSY also provides a step towards the realization of FAIR with studies on spin manipulation and polarization build-up of protons in polarized targets.« less

Recent results from the ILL NSEs

NASA Astrophysics Data System (ADS)

Farago, Bela

2007-07-01

In this paper I will try to present some recent results on less usual subjects, which I believe are forward pointing to fields which might develop faster as new sources/instruments become available. The first deals with an assembly of spherical microemulsions which under certain conditions self-organize themselves into a cubic phase. Applying contrast variation and covering the large dynamical range of NSE we just start to be able to identify the different kind of relaxations present [B. Molle, et al., Phys. Rev. Lett. 90 (2003) 068305]. The second shows a nice example of diffusion of alkane chains in porous material (zeolite). Here high resolution and high intensity were needed to pinpoint the predicted “window” effect [H. Jobic, et al., Angew. Chem. Int. Ed. 43(3) (2004) 364]. Finally some results on PMMA/PEO polymer blend will be shown, where the high count rate and simultaneous multi-Q measurement on IN11C made the experiment possible. Still improved resolution would be very welcome to fully extract all possible information [B. Farago, et al., Phys. Rev. E 72 (2005) 031809].

Recent Results from the MAJORANA DEMONSTRATOR

NASA Astrophysics Data System (ADS)

Gilliss, T.; Alvis, S. I.; Arnquist, I. J.; Avignone, F. T.; Barabash, A. S.; Barton, C. J.; Bertrand, F. E.; Bode, T.; Brudanin, V.; Busch, M.; Buuck, M.; Caldwell, T. S.; Chan, Y.-D.; Christofferson, C. D.; Chu, P.-H.; Cuesta, C.; Detwiler, J. A.; Dunagan, C.; Efremenko, Yu; Ejiri, H.; Elliott, S. R.; Giovanetti, G. K.; Green, M. P.; Gruszko, J.; Guinn, I. S.; Guiseppe, V. E.; Haufe, C. R.; Hehn, L.; Henning, R.; Hoppe, E. W.; Howe, M. A.; Keeter, K. J.; Kidd, M. F.; Konovalov, S. I.; Kouzes, R. T.; Lopez, A. M.; Martin, R. D.; Massarczyk, R.; Meijer, S. J.; Mertens, S.; Myslik, J.; O’Shaughnessy, C.; Othman, G.; Pettus, W.; Poon, A. W. P.; Radford, D. C.; Rager, J.; Reine, A. L.; Rielage, K.; Robertson, R. G. H.; Ruof, N. W.; Shanks, B.; Shirchenko, M.; Suriano, A. M.; Tedeschi, D.; Varner, R. L.; Vasilyev, S.; Vetter, K.; Vorren, K.; White, B. R.; Wilkerson, J. F.; Wiseman, C.; Xu, W.; Yakushev, E.; Yu, C.-H.; Yumatov, V.; Zhitnikov, I.; Zhu, B. X.

The MAJORANA Collaboration has completed construction and is now operating an array of high purity Ge detectors searching for neutrinoless double-beta decay (0νββ) in 76Ge. The array, known as the MAJORANA DEMONSTRATOR, is comprised of 44 kg of Ge detectors (30 kg enriched to 88% in 76Ge) installed in an ultra-low background compact shield at the Sanford Underground Research Facility in Lead, South Dakota. The primary goal of the DEMONSTRATOR is to establish a low-background design that can be scaled to a next-generation tonne-scale experiment. This work reports initial background levels in the 0νββ region of interest. Also presented are recent physics results leveraging P-type point-contact detectors with sub-keV energy thresholds to search for physics beyond the Standard Model; first results from searches for bosonic dark matter, solar axions, Pauli exclusion principle violation, and electron decay have been published. Finally, this work discusses the proposed tonne-scale 76Ge 0νββ LEGEND experiment.

Recent results from gammasphere

DOE PAGES

Lee, I. Y.; Clark, R. M.; Ward, D.; ...

2001-12-01

Three examples of recent nuclear structure studies using Gammasphere are discussed in this paper. (1) A rotational band has been identified in 108 Cd. Its moment of inertia and quadrupole moment indicate that this band has a shape with an axis ratio larger than 1.8:1. (2) Possible "Jacobi" shape transitions at high spin were investigated from studies of the continuum gamma rays on a number of nuclei. (3) Population of high-spin states in neutron-rich nuclei were studied in target fragmentation reactions. States with spin up to 6-12 were observed in a wide range of nuclei.

Beryllium for fusion application - recent results

NASA Astrophysics Data System (ADS)

Khomutov, A.; Barabash, V.; Chakin, V.; Chernov, V.; Davydov, D.; Gorokhov, V.; Kawamura, H.; Kolbasov, B.; Kupriyanov, I.; Longhurst, G.; Scaffidi-Argentina, F.; Shestakov, V.

2002-12-01

The main issues for the application of beryllium in fusion reactors are analyzed taking into account the latest results since the ICFRM-9 (Colorado, USA, October 1999) and presented at 5th IEA Be Workshop (10-12 October 2001, Moscow Russia). Considerable progress has been made recently in understanding the problems connected with the selection of the beryllium grades for different applications, characterization of the beryllium at relevant operational conditions (irradiation effects, thermal fatigue, etc.), and development of required manufacturing technologies. The key remaining problems related to the application of beryllium as an armour in near-term fusion reactors (e.g. ITER) are discussed. The features of the application of beryllium and beryllides as a neutron multiplier in the breeder blanket for power reactors (e.g. DEMO) in pebble-bed form are described.

Recent Results with CVD Diamond Trackers

NASA Astrophysics Data System (ADS)

Adam, W.; Bauer, C.; Berdermann, E.; Bergonzo, P.; Bogani, F.; Borchi, E.; Brambilla, A.; Bruzzi, M.; Colledani, C.; Conway, J.; Dabrowski, W.; Delpierre, P.; Deneuville, A.; Dulinski, W.; van Eijk, B.; Fallou, A.; Fizzotti, F.; Foulon, F.; Friedl, M.; Gan, K. K.; Gheeraert, E.; Grigoriev, E.; Hallewell, G.; Hall-Wilton, R.; Han, S.; Hartjes, F.; Hrubec, J.; Husson, D.; Kagan, H.; Kania, D.; Kaplon, J.; Karl, C.; Kass, R.; Knöpfle, K. T.; Krammer, M.; Logiudice, A.; Lu, R.; Manfredi, P. F.; Manfredotti, C.; Marshall, R. D.; Meier, D.; Mishina, M.; Oh, A.; Pan, L. S.; Palmieri, V. G.; Pernicka, M.; Peitz, A.; Pirollo, S.; Polesello, P.; Pretzl, K.; Procario, M.; Re, V.; Riester, J. L.; Roe, S.; Roff, D.; Rudge, A.; Runolfsson, O.; Russ, J.; Schnetzer, S.; Sciortino, S.; Speziali, V.; Stelzer, H.; Stone, R.; Suter, B.; Tapper, R. J.; Tesarek, R.; Trawick, M.; Trischuk, W.; Vittone, E.; Walsh, A. M.; Wedenig, R.; Weilhammer, P.; White, C.; Ziock, H.; Zoeller, M.; RD42 Collaboration

1999-08-01

We present recent results on the use of Chemical Vapor Deposition (CVD) diamond microstrip detectors for charged particle tracking. A series of detectors was fabricated using 1 x 1 cm 2 diamonds. Good signal-to-noise ratios were observed using both slow and fast readout electronics. For slow readout electronics, 2 μs shaping time, the most probable signal-to-noise ratio was 50 to 1. For fast readout electronics, 25 ns peaking time, the most probable signal-to-noise ratio was 7 to 1. Using the first 2 x 4 cm 2 diamond from a production CVD reactor with slow readout electronics, the most probable signal-to-noise ratio was 23 to 1. The spatial resolution achieved for the detectors was consistent with the digital resolution expected from the detector pitch.

Geochemistry of recent aragonite-rich sediments in Mediterranean karstic marine lakes: Trace elements as pollution and palaeoredox proxies and indicators of authigenic mineral formation.

PubMed

Sondi, Ivan; Mikac, Nevenka; Vdović, Neda; Ivanić, Maja; Furdek, Martina; Škapin, Srečo D

2017-02-01

This study investigates the geochemical characteristics of recent shallow-water aragonite-rich sediments from the karstic marine lakes located in the pristine environment on the island of Mljet (Adriatic Sea). Different trace elements were used as authigenic mineral formation, palaeoredox and pollution indicators. The distribution and the historical record of trace elements deposition mostly depended on the sedimentological processes associated with the formation of aragonite, early diagenetic processes governed by the prevailing physico-chemical conditions and on the recent anthropogenic activity. This study demonstrated that Sr could be used as a proxy indicating authigenic formation of aragonite in a marine carbonate sedimentological environment. Distribution of the redox sensitive elements Mo, Tl, U and Cd was used to identify changes in redox conditions in the investigated lake system and to determine the geochemical cycle of these elements through environmental changes over the last 100 years. The significant enrichment of these elements and the presence of early formed nanostructured authigenic framboidal pyrite in laminated deeper parts of sediment in Malo Jezero, indicate sporadic events of oxygen-depleted euxinic conditions in the recent past. Concentrations of trace elements were in the range characteristic for non-contaminated marine carbonates. However, the increase in the concentrations of Zn, Cu, Pb, Sn, Bi in the upper-most sediment strata of Veliko Jezero indicates a low level of trace element pollution, resulting from anthropogenic inputs over the last 40 years. The presence of butyltin compounds (BuTs) in the surface sediment of Veliko Jezero additionally indicates the anthropogenic influence in the recent past. Copyright © 2016 Elsevier Ltd. All rights reserved.

Some recent results from CLEO II

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kass, R.

1997-06-01

The CLEO experiment has been operating for several years now collecting e{sup +}e{sup {minus}} annihilation data at and near the {Upsilon}(4S) resonance (E{sub cm} {approx} 10.6 GeV). The accumulated event sample contains several million B{anti B} and {tau}{sup +}{tau}{sup {minus}} pairs. These data are used to explore rare b, c, and {tau} decays. In this report, several recent CLEO results in the area of B-meson and {tau} decay are presented. The topics covered include: penguin decays of B-mesons, measurement of exclusive b {r_arrow} u semileptonic transitions, {tau} decays with an {eta} in the final state, precision measurement of the Michelmore » parameters in leptonic {tau} decay, and a search for lepton number violation using {tau}`s. 39 refs., 26 figs.« less

News from the proton - recent DIS results from HERA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meier, K.

1997-01-01

Recent results from the two large general-purpose detectors H1 and ZEUS at HERA (DESY, Hamburg, Germany) are presented. Emphasis is given to the analysis of deep inelastic scattering defined by the observation of the scattered electron or positron in the main calorimeters. Results on purely inclusive cross sections lead to a determination of the charged (quarks) parton distribution F{sub 2}(x, Q{sup 2}). Access to the electrically neutral parton content (gluons) is obtained indirectly by an analysis of the expected scaling violation behavior of F{sub 2} or directly from multijet rates originating from well-defined initial parton configurations. Finally, the recently uncoveredmore » subclass of large rapidity gap (LRG) events has been analyzed in terms of F{sub 2}. The result supports the concept of a color neutral object (Pomeron IP) being probed by a hard scattering electron. Evidence for factorization of the Pomeron radiation process as well as for scaling in the inclusive IP structure functions has been found.« less

Recent progress in biopolymer nanoparticle and microparticle formation by heat-treating electrostatic protein-polysaccharide complexes.

PubMed

Jones, Owen G; McClements, David Julian

2011-09-14

Functional biopolymer nanoparticles or microparticles can be formed by heat treatment of globular protein-ionic polysaccharide electrostatic complexes under appropriate solution conditions. These biopolymer particles can be used as encapsulation and delivery systems, fat mimetics, lightening agents, or texture modifiers. This review highlights recent progress in the design and fabrication of biopolymer particles based on heating globular protein-ionic polysaccharide complexes above the thermal denaturation temperature of the proteins. The influence of biopolymer type, protein-polysaccharide ratio, pH, ionic strength, and thermal history on the characteristics of the biopolymer particles formed is reviewed. Our current understanding of the underlying physicochemical mechanisms of particle formation and properties is given. The information provided in this review should facilitate the rational design of biopolymer particles with specific physicochemical and functional attributes, as well as stimulate further research in identifying the physicochemical origin of particle formation. Copyright © 2010 Elsevier B.V. All rights reserved.

Involvement of the Anterior Cingulate Cortex in Formation, Consolidation, and Reconsolidation of Recent and Remote Contextual Fear Memory

ERIC Educational Resources Information Center

Einarsson, Einar O.; Nader, Karim

2012-01-01

It has been suggested that memories become more stable and less susceptible to the disruption of reconsolidation over weeks after learning. Here, we test this by targeting the anterior cingulate cortex (ACC) and test its involvement in the formation, consolidation, and reconsolidation of recent and remote contextual fear memory. We found that…

Recent Selected Ion Flow Tube (SIFT) Studies Concerning the Formation of Amino Acids in the Gas Phase

NASA Technical Reports Server (NTRS)

Jackson, Douglas M.; Adams, Nigel G.; Babcock, Lucia M.

2006-01-01

Recently the simplest amino acid, glycine, has been detected in interstellar clouds, ISC, although this has since been contested. In order to substantiate either of these claims, plausible routes to amino acids need to be investigated. For gas phase synthesis, the SIFT technique has been employed to study simple amino acids via ion-molecule reactions of several ions of interstellar interest with methylamine, ethylamine, formic acid, acetic acid, and methyl formate. Carboxylic acid type ions were considered in the reactions involving the amines. In reactions where the carboxylic acid and methyl formate neutrals were studied, the reactant ions were primarily amine ion fragments. It was observed that the amines and acids preferentially fragment or accept a proton whenever energetically possible. NH3(+), however, uniquely reacted with the neutrals via atom abstraction to form NH4(+). These studies yielded a body of data relevant to astrochemistry, supplementing the available literature. However, the search for gas phase routes to amino acids using conventional molecules has been frustrated. Our most recent research investigates the fragmentation patterns of several amino acids and several possible routes have been suggested for future study.

Presenting self-monitoring test results for consumers: the effects of graphical formats and age.

PubMed

Tao, Da; Yuan, Juan; Qu, Xingda

2018-05-11

To examine the effects of graphical formats and age on consumers' comprehension and perceptions of the use of self-monitoring test results. Participants (36 older and 36 young adults) were required to perform verbatim comprehension and value interpretation tasks with hypothetical self-monitoring test results. The test results were randomly presented by four reference range number lines: basic, color enhanced, color/text enhanced, and personalized information enhanced formats. We measured participants' task performance and eye movement data during task completion, and their perceptions and preference of the graphical formats. The 4 graphical formats yielded comparable task performance, while text/color and personalized information enhanced formats were believed to be easier and more useful in information comprehension, and led to increased confidence in correct comprehension of test results, compared with other formats (all p's < .05). Perceived health risk increased as the formats applied more information cues (p = .008). There were age differences in task performance and visual attention (all p's < .01), while young and older adults had similar perceptions for the 4 formats. Personalized information enhanced format was preferred by both groups. Text/color and personalized information cues appear to be useful for comprehending test results. Future work can be directed to improve the design of graphical formats especially for older adults, and to assess the formats in clinical settings.

An Overview of Recent PISCES Program PMI Results

NASA Astrophysics Data System (ADS)

Tynan, George; Doerner, Russell; Abe, Shota; Baldwin, Matthew; Barton, Joseph; Chen, Renkun; Gosselin, Jordan; Hollmann, Eric; Nishijima, Daisuke; Simmonds, Michael; Wang, Yong; Yu, Jonathan

2015-11-01

The PISCES Program is focused on fundamental PMI studies of Be and W-based solid plasma facing components under steady-state and transient conditions. We will show results from studies in W, Be and mixed W-Be material systems. Topics of investigation include formation of near-surface nanobubbles from He plasma ion implantation, growth of W-fuzz from these bubbles in steady-state and transient conditions, D retention in Be and W and development of a D-retention model for both H/D isotope exchange and displacement damage experiments. Initial studies of PMI in displacement damaged W are also presented, showing the effect of damage and exposure temperature on D retention, D diffusion, W thermal conductivity. Be-based results include morphology evolution under high plasma flux exposure, Be erosion mechanisms, and retention in Be-based materials. Future plans and connections to fusion energy system requirements will be discussed. This work supported by grant DE-FG02-07ER54912.

Recent Formation of Saturnian Moons: Constraints from Their Cratering Records

NASA Astrophysics Data System (ADS)

Dones, Henry C. Luke; Charnoz, Sebastien; Robbins, Stuart J.; Bierhaus, Edward B.

2015-05-01

Charnoz et al. (2010) proposed that Saturn's small "ring moons" out to Janus and Epimetheus consist of ring material that viscously spread beyond the Roche limit and coagulated into moonlets. The moonlets evolve outward due to the torques they exert at resonances in the rings. More massive moonlets migrate faster; orbits can cross and bodies can merge, resulting in a steep trend of mass vs. distance from the planet. Canup (2010) theorized that Saturn's rings are primordial and originated when a differentiated, Titan-like moon migrated inward when the planet was still surrounded by a gas disk. The satellite's icy shell could have been tidally stripped, and would have given rise to today's rings and the mid-sized moons out to Tethys. Charnoz et al. (2011) investigated the formation of satellites out to Rhea from a spreading massive ring, and Crida and Charnoz (2012) extended this scenario to other planets. Once the mid-sized moons recede far from the rings, tidal interaction with the planet determines the rate at which the satellites migrate. Charnoz et al. (2011) found that Mimas would have formed about 1 billion years more recently than Rhea. The cratering records of these moons (Kirchoff and Schenk 2010; Robbins et al. 2015) provide a test of this scenario. If the mid-sized moons are primordial, most of their craters were created through hypervelocity impacts by ecliptic comets from the Kuiper Belt/Scattered Disk (Zahnle et al. 2003; Dones et al. 2009). In the Charnoz et al. scenario, the oldest craters on the moons would result from low-speed accretionary impacts. We thank the Cassini Data Analysis program for support.ReferencesCanup, R. M. (2010). Nature 468, 943Charnoz, S.; Salmon, J., Crida, A. (2010). Nature 465, 752Charnoz, S., et al. (2011). Icarus 216, 535Crida, A.; Charnoz, S. (2012). Science 338, 1196Dones, L., et al. (2009). In Saturn from Cassini-Huygens, p. 613Kirchoff, M. R.; Schenk, P. (2010). Icarus 206, 485Robbins, S. J.; Bierhaus, E. B.; Dones, L

Recent sedimentological studies of the Murray and Stimson formations and their implications for Gale crater evolution, Mars

NASA Astrophysics Data System (ADS)

Gupta, Sanjeev; Fedo, Chris; Grotzinger, John; Edgett, Ken; Vasavada, Ashwin

2017-04-01

The Mars Science Laboratory (MSL) Curiosity rover has been exploring sedimentary rocks on the lower north slope of Aeolis Mons since August 2014. Previous work has demonstrated a succession of sedimentary rock types deposited dominantly in river-delta settings (Bradbury group), and interfingering/overlying contemporaneous/younger lake settings (Murray formation, Mt. Sharp group). The Murray formation is unconformably overlain by the Stimson formation, an ancient aeolian sand lithology. Here, we describe the MSL team's most recent sedimentological findings regarding the Murray and Stimson formations. The Murray formation is of the order of 200 meters thick and formed dominantly of mudstones. The mudstone facies, originally identified at the Pahrump Hills field site, show abundant fine-scale planar laminations throughout the Murray formation succession and is interpreted to record deposition in an ancient lake system in Gale crater. Since leaving the Naukluft Plateau (Stimson formation rocks) and driving south-southeastwards and progressive stratigraphically upwards through the Murray succession, we have recognised a variety of additional facies have been recognized that indicate variability in the overall palaeoenvironmental setting. These facies include (1) cross-bedded siltstones to very fine-grained sandstones with metre-scale troughs that might represent aeolian sedimentation; (2) a heterolithic mudstone-sandstone facies with laminated fine-grained strata, cm-scale ripple cross-laminations in siltstone or very fine sandstone, and dm-scale cross-stratified siltstone and very fine grained sandstone. The palaeoenvironmental setting for the second facies remains under discussion. Our results show that Gale crater hosted lakes systems for millions to tens of millions of years, perhaps punctuated by drier intervals. Murray strata are unconformably overlain by the Stimson formation. Stimson outcrops are typically characterized by cross-bedded sandstones with cross

P-MaNGA: GRADIENTS IN RECENT STAR FORMATION HISTORIES AS DIAGNOSTICS FOR GALAXY GROWTH AND DEATH

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Cheng; Wang, Enci; Lin, Lin

2015-05-10

We present an analysis of the data produced by the MaNGA prototype run (P-MaNGA), aiming to test how the radial gradients in recent star formation histories, as indicated by the 4000 Å break (D{sub n}(4000)), Hδ absorption (EW(Hδ{sub A})), and Hα emission (EW(Hα)) indices, can be useful for understanding disk growth and star formation cessation in local galaxies. We classify 12 galaxies observed on two P-MaNGA plates as either centrally quiescent (CQ) or centrally star-forming (CSF), according to whether D{sub n}(4000) measured in the central spaxel of each datacube exceeds 1.6. For each spaxel we generate both 2D maps and radialmore » profiles of D{sub n}(4000), EW(Hδ{sub A}), and EW(Hα). We find that CSF galaxies generally show very weak or no radial variation in these diagnostics. In contrast, CQ galaxies present significant radial gradients, in the sense that D{sub n}(4000) decreases, while both EW(Hδ{sub A}) and EW(Hα) increase from the galactic center outward. The outer regions of the galaxies show greater scatter on diagrams relating the three parameters than their central parts. In particular, the clear separation between centrally measured quiescent and star-forming galaxies in these diagnostic planes is largely filled in by the outer parts of galaxies whose global colors place them in the green valley, supporting the idea that the green valley represents a transition between blue-cloud and red-sequence phases, at least in our small sample. These results are consistent with a picture in which the cessation of star formation propagates from the center of a galaxy outward as it moves to the red sequence.« less

The Space Infrared Interferometric Telescope (SPIRIT): Recent Study Results and Plans

NASA Astrophysics Data System (ADS)

Leisawitz, David; SPIRIT Mission Study Team

2007-12-01

SPIRIT was recommended in the 2002 "Community Plan for Far-IR/Submillimeter Space Astronomy.” A structurally connected interferometer, SPIRIT provides sensitive sub-arcsecond angular resolution images and integral field spectroscopy in the 25 to 400 micron wavelength range. SPIRIT was designed to revolutionize our understanding of planetary system formation, reveal otherwise-undetectable planets through the disk perturbations they induce, spectroscopically probe the atmospheres of extrasolar giant planets in orbits typical of most of the planets in our solar system, and yield significant new insight into the processes associated with galaxy formation and development. This paper updates previously presented study results and describes future study plans. Our SPIRIT mission concept study proposal was peer reviewed and selected by NASA for support under the Origins Probe Mission Concept Study program. NASA's Goddard Space Flight Center and four industry partners - Ball Aerospace, Boeing, Lockheed-Martin, and Northrop-Grumman - contributed generously the study. The Origins Probe study results were reviewed by an Advisory Review Panel.

The Intra-cluster medium: recent results and future prospects

NASA Astrophysics Data System (ADS)

Molendi, Silvano

2010-07-01

This comunication is divided in two parts: in the first I present some recent observational results obtained by my group; in the second I list what I consider to be the top priorities in terms of X-ray instrumentation for cluster science and compare them with missions currently under development.

Recent Geologic Mapping Results for the Polar Regions of Mars

NASA Technical Reports Server (NTRS)

tanaka, K. L.; Kolb, E. J.

2008-01-01

The polar regions of Mars include the densest data coverage for the planet because of the polar orbits of MGS, ODY, and MEX. Because the geology of the polar plateaus has been among the most dynamic on the planet in recent geologic time, the data enable the most detailed and complex geologic investigations of any regions on Mars, superseding previous, even recent, mapping efforts [e.g., 1-3]. Geologic mapping at regional and local scales is revealing that the stratigraphy and modificational histories of polar materials by various processes are highly complex at both poles. Here, we describe some of our recent results in polar geologic mapping and how they address the geologic processes involved and implications for polar climate history.

Recent Results from MINERvA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fields, Laura

2016-12-21

The MINERvA collaboration is currently engaged in a broad program of neutrino-nucleus interaction measurements. Several recent measurements of interest to the accelerator-based oscillation community are presented. These include measurements of quasi-elastic scattering, diffractive pion production, kaon production and comparisons of interaction cross sections across nuclei. A new measurement of the NuMI neutrino beam flux that incorporates both external hadro-production data and MINERvA detector data is also presented.

Borexino: recent results, detector calibration and future perspectives

NASA Astrophysics Data System (ADS)

Pallavicini, Marco; Bellini, G.; Benziger, J.; Bonetti, S.; Buizza Avanzini, M.; Caccianiga, B.; Cadonati, L.; Calaprice, F.; Carraro, C.; Chavarria, A.; Dalnoki-Veress, F.; D'Angelo, D.; Davini, S.; de Kerret, H.; Derbin, A.; Etenko, A.; von Feilitzsch, F.; Fomenko, K.; Franco, D.; Galbiati, C.; Gazzana, S.; Ghiano, C.; Giammarchi, M.; Goeger-Neff, M.; Goretti, A.; Guardincerri, E.; Hardy, S.; Ianni, Aldo; Ianni, Andrea; Joyce, M.; Kobychev, V.; Koshio, Y.; Korga, G.; Kryn, D.; Laubenstein, M.; Leung, M.; Lewke, T.; Litvinovich, E.; Loer, B.; Lombardi, F.; Lombardi, P.; Ludhova, L.; Machulin, I.; Manecki, S.; Maneschg, W.; Manuzio, G.; Meindl, Q.; Meroni, E.; Miramonti, L.; Misiaszek, M.; Montanari, D.; Muratova, V.; Oberauer, L.; Obolensky, M.; Ortica, F.; Pallavicini, M.; Papp, L.; Perasso, L.; Perasso, S.; Pocar, A.; Raghavan, R. S.; Ranucci, G.; Razeto, A.; Re, A.; Risso, P.; Romani, A.; Rountree, D.; Sabelnikov, A.; Saldanha, R.; Salvo, C.; Schönert, S.; Simgen, H.; Skorokhvatov, M.; Smirnov, O.; Sotnikov, A.; Sukhotin, S.; Suvorov, Y.; Tartaglia, R.; Testera, G.; Vignaud, D.; Vogelaar, R. B.; Winter, J.; Wojcik, M.; Wurm, M.; Wright, A.; Xu, J.; Zaimidoroga, O.; Zavatarelli, S.; Zuzel, G.; Borexino Collaboration

2011-08-01

The Borexino experiment has been running since May 2007 at the Gran Sasso underground laboratory, in Italy. Solar neutrinos are detected with a large unsegmented liquid scintillator detector with unprecedented radioactive purity. The main results obtained include the measurement of the 7Be solar neutrino flux, the measurement of the 8B neutrino flux with electron recoil energy threshold of 3.0 MeV and the first clear detection of geo-neutrinos (see Aldo Ianni's talk in these proceedings for further details). Borexino has recently completed a large calibration campaign, and better results on 7Be solar neutrino measurement are expected soon. Short and medium term perspectives are summarized in the conclusions.

Recent glacier retreat and lake formation in the Querecocha watershed, Cordillera Blanca, Peru

NASA Astrophysics Data System (ADS)

López Moreno, J.; Valero-Garces, B.; Revuelto, J.; Azorín-Molina, C.; Bazo, J.; Cochachin, A.; Fontaneda, S.; Mark, B. G.

2013-12-01

In the Andes, and specifically in the Peruvian mountains a marked decrease of the glaciated area has occurred since the end of the Little Ice Age, and it has been accelerated since the last decades of the 20th century. As a result of the glacier retreat new pro-glaciar lakes are originated, and often the area and volume of existing ones increases. The study of these newly-formed lakes and their recent evolution may provide a better understanding of the hydrological and geomorphological evolution of deglaciated areas, and a better evaluation of the risk of glacial lakes outburst floods (GLOFS). In this work, we use 26 annual Landsat Thematic Mapper images from 1975 to 2010 to determine changes of the glaciated surface, snow line elevation and lakes formation in the headwaters of the Querecocha watershed in Cordillera Blanca (Perú). We also present the information derived from 10 short sediment cores (up to 50 cm long) retrieved along several transects in Yanamarey Lake. Both data sets inform of the sediment yield and lake development in recently deglaciated environments of the Andes. Results demonstrate that only one third of the surface covered by ice in 1975 remained in 2010. In this period, snowline has shifted up more than 100 meters in elevation in both, Yanamarey North and South areas respectively. At the same time, new lakes have been formed very quickly in these deglaciated areas. Preliminary 137Cs dating of Yanamarey sediment core indicates that at least the top 50 cm of the lake sequence deposited after 1960. This is coherent with the Landsat image of 1975 that showed the current surface of the lake still covered by ice. The high sediment rate (> 1 cm/yr) in the lake demonstrates the very high sediment yield in these geomorphically active settings. The sediment cores are composed of cm-thick sequences defined by grain-size (silt-clay) common in proglacial lakes reflecting the variability of hydrological response associated to the glacier retreat in the

Recent CCQE results from MINERvA

NASA Astrophysics Data System (ADS)

Ghosh, Anushree; Minerva Collaboration

2017-01-01

The MINER νA detector situated in Fermilab, is designed to make precision cross section measurements for neutrino scattering processes on various nuclei. I will present the two most recent results from the MINER νA charged current quasi-elastic (CCQE) studies. The event sample for both analyses are the CCQE-like final state topology and contain contributions from quasi-elastic and inelastic processes where pions are absorbed in the nucleus. One of the analyses is the MINER νA experiment's first double-differential scattering cross sections for antineutrinos on the hydrocarbon target in the few-GeV range relevant to experiments such as DUNE and NOvA. We compare to models produced by different model generators, and are able to draw first conclusions about the predictions of these models. Another analysis, is the CCQE-like analysis for neutrinos on the nuclear targets of carbon, iron and lead. The ratio of differential cross sections on these targets to the differential cross section on the hydrocarbon target are examined to study nuclear effects.

Satellite Formation Flight Results from Phase 1 of the Magnetospheric Multiscale Mission

NASA Technical Reports Server (NTRS)

Williams, Trevor; Ottenstein, Neil; Palmer, Eric; Godine, Dominic

2017-01-01

This paper describes the underlying dynamics of formation flying in a high-eccentricity orbit such as that of the Magnetospheric Multiscale mission. The GPS-based results used for MMS navigation are summarized, as well as the procedures that are used to design the maneuvers used to place the spacecraft into a tetrahedron formation and then maintain it. The details of how to carry out these maneuvers are then discussed. Finally, the numerical results that have been obtained concerning formation flying for the MMS mission to date (e.g. tetrahedron sizes flown, maneuver execution error, fuel usage, etc.) are presented in detail.

Recent rift formation and impact on the structural integrity of the Brunt Ice Shelf, East Antarctica

NASA Astrophysics Data System (ADS)

De Rydt, Jan; Hilmar Gudmundsson, G.; Nagler, Thomas; Wuite, Jan; King, Edward C.

2018-02-01

We report on the recent reactivation of a large rift in the Brunt Ice Shelf, East Antarctica, in December 2012 and the formation of a 50 km long new rift in October 2016. Observations from a suite of ground-based and remote sensing instruments between January 2000 and July 2017 were used to track progress of both rifts in unprecedented detail. Results reveal a steady accelerating trend in their width, in combination with alternating episodes of fast ( > 600 m day-1) and slow propagation of the rift tip, controlled by the heterogeneous structure of the ice shelf. A numerical ice flow model and a simple propagation algorithm based on the stress distribution in the ice shelf were successfully used to hindcast the observed trajectories and to simulate future rift progression under different assumptions. Results show a high likelihood of ice loss at the McDonald Ice Rumples, the only pinning point of the ice shelf. The nascent iceberg calving and associated reduction in pinning of the Brunt Ice Shelf may provide a uniquely monitored natural experiment of ice shelf variability and provoke a deeper understanding of similar processes elsewhere in Antarctica.

Autonomous formation flying based on GPS — PRISMA flight results

NASA Astrophysics Data System (ADS)

D'Amico, Simone; Ardaens, Jean-Sebastien; De Florio, Sergio

2013-01-01

This paper presents flight results from the early harvest of the Spaceborne Autonomous Formation Flying Experiment (SAFE) conducted in the frame of the Swedish PRISMA technology demonstration mission. SAFE represents one of the first demonstrations in low Earth orbit of an advanced guidance, navigation and control system for dual-spacecraft formations. Innovative techniques based on differential GPS-based navigation and relative orbital elements control are validated and tuned in orbit to fulfill the typical requirements of future distributed scientific instruments for remote sensing.

Experimental investigations of recent anomalous results in superconductivity

NASA Astrophysics Data System (ADS)

Souw, Victor K.

2000-12-01

This thesis examines three recent anomalous results associated with irreversibility in type-II superconductivity: (1) The magnetic properties of the predicted superconductors LiBeH3 and Li2BeH 4, (2) the paramagnetic transition near T = Tc in Nb, and (3) a noise transition in a YBa2Cu3O7-delta thin film near the vortex-solid transition. The investigation of Li 2BeH4 and LiBeH3 was prompted by theoretical predictions of room-temperature superconductivity for Li2BeH4 and LiBeH3 and a recent report that Li2BeH4 showed magnetic irreversibilities similar to those of type-II superconductors. A modified experimental method is introduced in order to avoid artifacts due to background signals. The resulting data is suggestive of a superparamagnetic impurity from one of the reagents used in the synthesis and after subtracting this contribution, the temperature-dependent susceptibilities of Li2 BeH4 and LiBeH3 are estimated. However, no magnetic irreversibility suggestive of superconductivity is observed. The anomalous paramagnetic transition in Nb is intriguing because Nb does not share the d-wave order parameter symmetry often invoked to explain the phenomenon in other superconductors. A modified experimental method was developed in order to avoid instrumental artifacts known to produce a similar apparently paramagnetic response, but the results of this method indicate that the paramagnetic response is a physical property of the sample. Finally, a very sharp noise transition in a YBa2Cu3O7-delta thin film was found to be distinct from previously reported features in the voltage noise commonly associated with vortex fluctuations near the irreversibility line. In each of these three cases the examination of experimental techniques is an integral part of the investigation of novel vortex behavior near the onset of irreversibility.

The ASCD Healthy School Communities Project: Formative Evaluation Results

ERIC Educational Resources Information Center

Valois, Robert F.; Lewallen, Theresa C.; Slade, Sean; Tasco, Adriane N.

2015-01-01

Purpose: The purpose of this paper is to report the formative evaluation results from the Association for Supervision and Curriculum Development Healthy School Communities (HSC) pilot project. Design/methodology/approach: This study utilized 11 HSC pilot sites in the USA (eight sites) and Canada (three sites). The evaluation question was…

Results of NASA's First Autonomous Formation Flying Experiment: Earth Observing-1 (EO-1)

NASA Technical Reports Server (NTRS)

Folta, David C.; Hawkins, Albin; Bauer, Frank H. (Technical Monitor)

2001-01-01

NASA's first autonomous formation flying mission completed its primary goal of demonstrating an advanced technology called enhanced formation flying. To enable this technology, the Guidance, Navigation, and Control center at the Goddard Space Flight Center (GSFC) implemented a universal 3-axis formation flying algorithm in an autonomous executive flight code onboard the New Millennium Program's (NMP) Earth Observing-1 (EO-1) spacecraft. This paper describes the mathematical background of the autonomous formation flying algorithm and the onboard flight design and presents the validation results of this unique system. Results from functionality assessment through fully autonomous maneuver control are presented as comparisons between the onboard EO-1 operational autonomous control system called AutoCon(tm), its ground-based predecessor, and a standalone algorithm.

Recent results in visual servoing

NASA Astrophysics Data System (ADS)

Chaumette, François

2008-06-01

Visual servoing techniques consist in using the data provided by a vision sensor in order to control the motions of a dynamic system. Such systems are usually robot arms, mobile robots, aerial robots,… but can also be virtual robots for applications in computer animation, or even a virtual camera for applications in computer vision and augmented reality. A large variety of positioning tasks, or mobile target tracking, can be implemented by controlling from one to all the degrees of freedom of the system. Whatever the sensor configuration, which can vary from one on-board camera on the robot end-effector to several free-standing cameras, a set of visual features has to be selected at best from the image measurements available, allowing to control the degrees of freedom desired. A control law has also to be designed so that these visual features reach a desired value, defining a correct realization of the task. With a vision sensor providing 2D measurements, potential visual features are numerous, since as well 2D data (coordinates of feature points in the image, moments, …) as 3D data provided by a localization algorithm exploiting the extracted 2D measurements can be considered. It is also possible to combine 2D and 3D visual features to take the advantages of each approach while avoiding their respective drawbacks. From the selected visual features, the behavior of the system will have particular properties as for stability, robustness with respect to noise or to calibration errors, robot 3D trajectory, etc. The talk will present the main basic aspects of visual servoing, as well as technical advances obtained recently in the field inside the Lagadic group at INRIA/INRISA Rennes. Several application results will be also described.

Recent Results on Singularity Strengths

NASA Astrophysics Data System (ADS)

Nolan, Brien

2002-12-01

In this contribution, we review some recent results on strengths of singularities. In a space-time (M,g), let γ[τ0, 0) → M be an incomplete, inextendible causal geodesic, affinely parametrised by τ, tangent ěc k. Let Jτ1 :=set of Jacobi fields along γ, orthogonal to γ and vanishing at time τ1 ≥ τ0 i.e. ěc ξ ∈ J{τ 1 } iff D2ξa = -Rbcdakbkdξc, gabξakb = 0, and ěc ξ (τ 1 ) = 0. Vτ1(τ) := volume element defined by full set of independent elements of Jτ1 (2-dim for null geodesies, 3-dim for time-like); Vτ1 := ∥Vτ1∥. Definition (Tipler 1977): γ terminates in a gravitationally strong singularity if for all 0 > τ1 ≥ τ0, lim infτ→0- Vτ1(τ) = 0. γ... gravitationally weak ... lim infτ→0- Vτ1(τ) > 0. The interpretation is that at a strong singularity, an extended body, e.g. a gravitational wave detector, is crushed to zero volume by the singularity. Tipler's definition does not take account of the possibility that (i) V → ∞ or (ii) V → finite, non-zero value, but with infinite stretching/crushing in orthogonal directions ('spaghettifying singularity'). Extended definition (Nolan 1999): strong if either V → 0,∞ or if for every τ1, there is an element ěc ξ of Jτ1 satisfying ||ěc ξ || -> 0. Otherwise weak. (Ori 2000): singularity is 'deformationally strong' if either (i) it is Tipler-strong or (ii) for every τ1, there is an element ěc ξ of Jτ1 satisfying ||ěc ξ || -> ∞ . Otherwise, deformationally weak...

Enhanced atomic gas fractions in recently merged galaxies: quenching is not a result of post-merger gas exhaustion.

NASA Astrophysics Data System (ADS)

Ellison, Sara L.; Catinella, Barbara; Cortese, Luca

2018-05-01

We present a detailed assessment of the global atomic hydrogen gas fraction (fgas=log[MHI/M⋆]) in a sample of post-merger galaxies identified in the Sloan Digital Sky Survey (SDSS). Archival H I measurements of 47 targets are combined with new Arecibo observations of a further 51 galaxies. The stellar mass range of the post-merger sample, our observing strategy, detection thresholds and data analysis procedures replicate those of the extended GALEX Arecibo SDSS Survey (xGASS) which can therefore be used as a control sample. Our principal results are: 1) The post-merger sample shows a ˜ 50 per cent higher H I detection fraction compared with xGASS; 2) Accounting for non-detections, the median atomic gas fraction of the post-merger sample is larger than the control sample by 0.3 - 0.6 dex; 3) The median atomic gas fraction enhancement (Δfgas), computed on a galaxy-by-galaxy basis at fixed stellar mass, is 0.51 dex. Our results demonstrate that recently merged galaxies are typically a factor of ˜ 3 more H I rich than control galaxies of the same M⋆. If the control sample is additionally matched in star formation rate, the median H I excess is reduced to Δfgas = 0.2 dex, showing that the enhanced atomic gas fractions in post-mergers are not purely a reflection of changes in star formation activity. We conclude that merger-induced starbursts and outflows do not lead to prompt quenching via exhaustion/expulsion of the galactic gas reservoirs. Instead, we propose that if star formation ceases after a merger, it is more likely due to an enhanced turbulence which renders the galaxy unable to effectively form new stars.

Recent Results from KASCADE-Grande and LOPES

NASA Astrophysics Data System (ADS)

Kascade-Grande; Lopes Collaboration; Kampert, K.-H.; Apel, W. D.; Arteaga, J. C.; Asch, T.; Badea, F.; Bähren, L.; Bekk, K.; Bertaina, M.; Biermann, P. L.; Blümer, J.; Bozdog, H.; Brancus, I. M.; Brüggemann, M.; Buchholz, P.; Buitink, S.; Cantoni, E.; Chiavassa, A.; Cossavella, F.; Daumiller, K.; de Souza, V.; di Pierro, F.; Doll, P.; Ender, M.; Engel, R.; Engler, J.; Falcke, H.; Finger, M.; Fuhrmann, D.; Gemmeke, H.; Ghia, P. L.; Gils, H. J.; Glasstetter, R.; Grupen, C.; Haungs, A.; Heck, D.; Hörandel, J. R.; Horneffer, A.; Huege, T.; Isar, P. G.; Kang, D.; Kickelbick, D.; Klages, H. O.; Kolotaev, Y.; Krömer, O.; Kuijpers, J.; Lafebre, S.; Link, K.; Łuczak, P.; Ludwig, M.; Mathes, H. J.; Mayer, H. J.; Milke, J.; Melissas, M.; Mitrica, B.; Morello, C.; Navarra, G.; Nehls, S.; Nigl, A.; Oehlschläger, J.; Ostapchenko, S.; Over, S.; Palmieri, N.; Petcu, M.; Pierog, T.; Rautenberg, J.; Rebel, H.; Roth, M.; Saftoiu, A.; Schieler, H.; Schmidt, A.; Schröder, F.; Sima, O.; Singh, K.; Stümpert, M.; Toma, G.; Trinchero, G.; Ulrich, H.; Walkowiak, W.; Weindl, A.; Wochele, J.; Wommer, M.; Zabierowski, J.; Zensus, J. A.; KASCADE-Grande and LOPES Collaboration

2009-05-01

KASCADE-Grande is an extensive air-shower experiment located at Forschungszentrum Karlsruhe, Germany. Main parts of the experiment are the Grande array spread over an area of 700×700 m, the original KASCADE array covering 200×200 m with unshielded and shielded detectors, and additional muon tracking devices. This multi-detector system allows to investigate the energy spectrum, composition, and anisotropies of cosmic rays in the energy range up to 1 EeV. LOPES is co-located at the same site to measure radio pulses from extensive air showers in coincidence with KASCADE-Grande. It consists of 30 digital antennas operated in different geometrical configurations. Read out is performed at high bandwidths and rate data processing with the aim to calibrate the emitted signal in the primary energy range of 10-10 eV by making use of reconstructed air-shower observables of KASCADE-Grande. An overview on the performance of both experiments will be given and recent analysis results be reported.

Recent Results from MINERvA

NASA Astrophysics Data System (ADS)

Dytman, Steven

2016-03-01

Neutrino cross sections are important both as a key component of neutrino oscillation experiments and as a way to study the axial and vector response in nuclear systems. MINERvA is a neutrino cross section experiment that has been taking data at Fermilab since 2009. The beam energy is well-matched to existing oscillation experiments such as MINOS/MINOS + and NOvA and planned experiments such as DUNE. The experiment has the unique capability to measure cross sections simultaneously with hydrocarbon, iron, and lead targets. Numerous publications have provided new data for neutrino and antineutrino interactions in these targets including quasielastic, pion production, and inclusive processes. This talk will present a series of recent measurements, their relationship to oscillation experiments and to nuclear physics.

SIM Interferometer Testbed (SCDU) Status and Recent Results

NASA Technical Reports Server (NTRS)

Nemati, Bijan; An, Xin; Goullioud, Renaud; Shao, Michael; Shen, Tsae-Pyng; Wehmeier, Udo J.; Weilert, Mark A.; Wang, Xu; Werne, Thomas A.; Wu, Janet P.;

Cosmic strings and galaxy formation

NASA Technical Reports Server (NTRS)

Bertschinger, Edmund

1989-01-01

The cosmogonical model proposed by Zel'dovich and Vilenkin (1981), in which superconducting cosmic strings act as seeds for the origin of structure in the universe, is discussed, summarizing the results of recent theoretical investigations. Consideration is given to the formation of cosmic strings, the microscopic structure of strings, gravitational effects, cosmic string evolution, and the formation of galaxies and large-scale structure. Simulation results are presented in graphs, and several outstanding issues are listed and briefly characterized.

Recent results of high p(T) physics at the CDF II

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tsuno, Soushi; /Okayama U.

2005-02-01

The Tevatron Run II program has been in progress since 2001. The CDF experiment has accumulated roughly five times as much data as did Run I, with much improved detectors. Preliminary results from the CDF experiment are presented. The authors focus on recent high p{sub T} physics results in the Tevatron Run II program.

Recent results and perspectives on cosmology and fundamental physics from microwave surveys

NASA Astrophysics Data System (ADS)

Burigana, Carlo; Battistelli, Elia Stefano; Benetti, Micol; Cabass, Giovanni; de Bernardis, Paolo; di Serego Alighieri, Sperello; di Valentino, Eleonora; Gerbino, Martina; Giusarma, Elena; Gruppuso, Alessandro; Liguori, Michele; Masi, Silvia; Norgaard-Nielsen, Hans Ulrik; Rosati, Piero; Salvati, Laura; Trombetti, Tiziana; Vielva, Patricio

2016-04-01

Recent cosmic microwave background (CMB) data in temperature and polarization have reached high precision in estimating all the parameters that describe the current so-called standard cosmological model. Recent results about the integrated Sachs-Wolfe (ISW) effect from CMB anisotropies, galaxy surveys, and their cross-correlations are presented. Looking at fine signatures in the CMB, such as the lack of power at low multipoles, the primordial power spectrum (PPS) and the bounds on non-Gaussianities, complemented by galaxy surveys, we discuss inflationary physics and the generation of primordial perturbations in the early universe. Three important topics in particle physics, the bounds on neutrinos masses and parameters, on thermal axion mass and on the neutron lifetime derived from cosmological data are reviewed, with attention to the comparison with laboratory experiment results. Recent results from cosmic polarization rotation (CPR) analyses aimed at testing the Einstein equivalence principle (EEP) are presented. Finally, we discuss the perspectives of next radio facilities for the improvement of the analysis of future CMB spectral distortion experiments.

Understanding Gully Formation and Seasonal Flows on Recent and Current Mars

NASA Astrophysics Data System (ADS)

Gulick, Virginia C.; Glines, Natalie

2016-10-01

The discoveries of gullies and seasonal slope flows (RSL) have re-ignited the debate over various channel, valley, and gully formation mechanisms on Mars. The controversy over whether liquid water was involved with gully formation, harkens back to the mid-1970s to early 2000s, where catastrophic flooding, surface runnoff and ground-water sapping processes were strongly debated along with other mechanisms as the primary processes responsible for channel and valley formation on Mars. However, over the past decade, the value of multiple working hypotheses has again become apparent, this time in understanding the formation of Martian gullies and Recurring Slope Lineae. Various mechanisms put forth to explain these landforms include liquid H2O/ice erosion, CO2 ice/frost sublimation, CO2 ice block sliding, water and brine flows, salt deliquescence, and dry granular flows, among others.We carried out detailed morphologic/morphometric studies of gullies in various environmental settings on Mars to evaluate the potential formation processes. Using HiRISE images and DTMs, we mapped and generated detailed longitudinal and cross-sectional profiles of gully systems and estimated volumes for both the gullies and their debris aprons. Several gullies form highly integrated patterns similar to fluvial systems. Additionally, RSL are often found either in the tributaries of these integrated systems or in adjacent regions, implying that RSL may play a role in initiating gully formation or mark the last vestiges of water activity in these locations. We also find that the more highly integrated gullies have volumes significantly larger than their aprons, suggesting that the missing volumes (~40-60% or more) were likely the volatiles involved in gully formation. Additionally, THEMIS and TES surface temperatures of these integrated gully sites, many of which also contain RSL, are at or above freezing seasonally suggesting that the volatile component may be consistent with H2O although CO2

Recent results on celestial gamma radiation from SMM

NASA Technical Reports Server (NTRS)

Share, Gerald H.

1991-01-01

Observations made by the Gamma Ray Spectrometer on board the SMM are described. Recent results reported include observations and analyses of gamma-ray lines from Co-56 produced in supernovae, observations of the temporal variation of the 511 keV line observed during Galactic center transits, and measurements of the diffuse Galactic spectrum from 0.3 to 8.5 MeV. The work in progress includes measurements of the distribution of Galactic Al-26, observations to place limits on Galactic Ti-44 and Fe-60 and on Be-7 produced in novae, and searches for a characteristic gamma-ray emission from pair plasmas, a 2.223 MeV line emission, limits on deexcitation lines from interstellar C and O, and gamma-ray bursts.

Recent results in the NASA research balloon program

NASA Technical Reports Server (NTRS)

Jones, W. Vernon

1989-01-01

The NASA Balloon Program has progressed from a total hiatus in the fall of 1985 to an unprecedented flight success rate in the fall of 1988. Using heavy-lift balloons being regularly supplied by two manufacturers, the program has provided a timely response for investigations of Supernova 1987A from Australia, low energy cosmic ray investigations from Canada during periods of near-solar-minimum, and routine domestic turnaround flights for a variety of investigations. Recent re-evaluation of balloon flight-safety have resulted in severe constraints on flights launched from the Palestine, Texas facility. The future program must rely heavily on the use of remote launch sites to meet the growing requirements for more frequent and longer duration flights being planned for the next 3 - 5 years.

Dysphagia in supratentorial recent small subcortical infarcts results from bilateral pyramidal tract damage.

PubMed

Fandler, Simon; Gattringer, Thomas; Pinter, Daniela; Pirpamer, Lukas; Borsodi, Florian; Eppinger, Sebastian; Niederkorn, Kurt; Enzinger, Christian; Fazekas, Franz

2018-01-01

Background Dysphagia occurs in up to 20% of patients with a recent small subcortical infarct, even when excluding brainstem infarcts. Aim To examine the impact of lesion topography and concomitant cerebrovascular lesions on the occurrence of dysphagia in patients with a single supratentorial recent small subcortical infarct. Methods We retrospectively identified all inpatients with magnetic resonance imaging-confirmed supratentorial recent small subcortical infarcts over a five-year period. Dysphagia was determined by speech-language therapists. Recent small subcortical infarcts were compiled into a standard brain model and compared using lesion probability maps. Furthermore, magnetic resonance imaging scans were reviewed for the combination of both acute and old cerebrovascular lesions. Results A total of 243 patients with a recent small subcortical infarct were identified (mean age 67.9 ± 12.2 years). Of those, 29 had mild and 18 moderate-to-severe dysphagia. Lesion probability maps suggested no recent small subcortical infarct location favoring the occurrence of moderate-to-severe dysphagia. However, patients with moderate-to-severe dysphagia more frequently showed combined damage to both pyramidal tracts by the recent small subcortical infarct and a contralateral old lesion (lacune: 77.8% vs. 19.9%, p < 0.001; lacune or confluent white matter hyperintensities: 100% vs. 57.7%, p < 0.001) than patients without swallowing dysfunction. Comparable results were obtained when analyzing patients with any degree of dysphagia. Conclusions Preexisting contralateral vascular pyramidal tract lesions are closely related to the occurrence of moderate-to-severe dysphagia in patients with supratentorial recent small subcortical infarcts.

Precision Formation Keeping at L2 Using the Autonomous Formation Flying Sensor

NASA Technical Reports Server (NTRS)

McLoughlin, Terence H.; Campbell, Mark

2004-01-01

Recent advances in formation keeping for large numbers of spacecraft using the Autonomous Formation Flying are presented. This sensor, currently under development at JPL, has been identified as a key component in future formation flying spacecraft missions. The sensor provides accurate range and bearing measurements between pairs of spacecraft using GPS technology. Previous theoretical work by the authors has focused on developing a decentralized scheduling algorithm to control the tasking of such a sensor between the relative range and bearing measurements to each node in the formation. The resulting algorithm has been modified to include switching constraints in the sensor. This paper also presents a testbed for real time validation of a sixteen-node formation based on the Stellar Imager mission. Key aspects of the simulation include minimum fuel maneuvers based on free-body dynamics and a three body propagator for simulating the formation at L2.

An Overview of Flight Test Results for a Formation Flight Autopilot

NASA Technical Reports Server (NTRS)

Hanson, Curtis E.; Ryan, Jack; Allen, Michael J.; Jacobson, Steven R.

2002-01-01

The first flight test phase of the NASA Dryden Flight Research Center Autonomous Formation Flight project has successfully demonstrated precision autonomous station-keeping of an F/A-18 research airplane with a second F/A-18 airplane. Blended inertial navigation system (INS) and global positioning system (GPS) measurements have been communicated across an air-to-air telemetry link and used to compute relative-position estimates. A precision research formation autopilot onboard the trailing airplane controls lateral and vertical spacing while the leading airplane operates under production autopilot control. Four research autopilot gain sets have been designed and flight-tested, and each exceeds the project design requirement of steady-state tracking accuracy within 1 standard deviation of 10 ft. Performance also has been demonstrated using single- and multiple-axis inputs such as step commands and frequency sweeps. This report briefly describes the experimental formation flight systems employed and discusses the navigation, guidance, and control algorithms that have been flight-tested. An overview of the flight test results of the formation autopilot during steady-state tracking and maneuvering flight is presented.

MINE WASTE TECHNOLOGY PROGRAM: RECENT RESULTS: LESSONS LEARNED AND FUTURE OPPORTUNITIES

EPA Science Inventory

In the EPA sponsored AML workshop, a number of Mine Waste Technology Program (MWTP) projects will be presented in order to highlight the most successful technology demonstrations. Recent results, lesson learned and future opportunities will be presented. The MWTP projects includ...

Photosynthetic dioxygen formation studied by time-resolved delayed fluorescence measurements--method, rationale, and results on the activation energy of dioxygen formation.

PubMed

Buchta, Joachim; Grabolle, Markus; Dau, Holger

2007-06-01

The analysis of the time-resolved delayed fluorescence (DF) measurements represents an important tool to study quantitatively light-induced electron transfer as well as associated processes, e.g. proton movements, at the donor side of photosystem II (PSII). This method can provide, inter alia, insights in the functionally important inner-protein proton movements, which are hardly detectable by conventional spectroscopic approaches. The underlying rationale and experimental details of the method are described. The delayed emission of chlorophyll fluorescence of highly active PSII membrane particles was measured in the time domain from 10 mus to 60 ms after each flash of a train of nanosecond laser pulses. Focusing on the oxygen-formation step induced by the third flash, we find that the recently reported formation of an S4-intermediate prior to the onset of O-O bond formation [M. Haumann, P. Liebisch, C. Müller, M. Barra, M. Grabolle, H. Dau, Science 310, 1019-1021, 2006] is a multiphasic process, as anticipated for proton movements from the manganese complex of PSII to the aqueous bulk phase. The S4-formation involves three or more likely sequential steps; a tri-exponential fit yields time constants of 14, 65, and 200 mus (at 20 degrees C, pH 6.4). We determine that S4-formation is characterized by a sizable difference in Gibbs free energy of more than 90 meV (20 degrees C, pH 6.4). In the second part of the study, the temperature dependence (-2.7 to 27.5 degrees C) of the rate constant of dioxygen formation (600/s at 20 degrees C) was investigated by analysis of DF transients. If the activation energy is assumed to be temperature-independent, a value of 230 meV is determined. There are weak indications for a biphasicity in the Arrhenius plot, but clear-cut evidence for a temperature-dependent switch between two activation energies, which would point to the existence of two distinct rate-limiting steps, is not obtained.

Satellite Communications for Aeronautical Applications: Recent research and Development Results

NASA Technical Reports Server (NTRS)

Kerczewski, Robert J.

2001-01-01

Communications systems have always been a critical element in aviation. Until recently, nearly all communications between the ground and aircraft have been based on analog voice technology. But the future of global aviation requires a more sophisticated "information infrastructure" which not only provides more and better communications, but integrates the key information functions (communications, navigation, and surveillance) into a modern, network-based infrastructure. Satellite communications will play an increasing role in providing information infrastructure solutions for aviation. Developing and adapting satellite communications technologies for aviation use is now receiving increased attention as the urgency to develop information infrastructure solutions grows. The NASA Glenn Research Center is actively involved in research and development activities for aeronautical satellite communications, with a key emphasis on air traffic management communications needs. This paper describes the recent results and status of NASA Glenn's research program.

From Deuterium to Free Neutrons - Recent Experimental Results

NASA Astrophysics Data System (ADS)

Kuhn, Sebastian

2009-05-01

Lepton scattering has long been used to gather data on the internal structure of both protons and neutrons. Assuming isospin symmetry, these data can be used to pin down the contributions of both u and d quarks to the spatial and momentum-spin structure of the nucleon and its excitations. In this context, information on the neutron is crucial and is typically obtained from experiments on few-body nuclear targets (predominantly ^3He and deuterium). However, the need to account for binding effects complicates the interpretation of these experiments. On the other hand, detailed studies of the reaction mechanism can yield important new information on the structure of few-body nuclei and the interplay of nuclear and quark degrees of freedom. Recent theoretical and experimental advances have allowed us to make significant progress on both fronts -- a cleaner extraction of neutron properties from nuclear data and a better understanding of nuclear modifications of the bound neutron structure. I will concentrate on recent results on the deuteron. I will present a new extraction of neutron spin structure functions in the resonance and large-x region (from the EG1 experiment with CLAS at Jefferson Lab). The same data can also be used for a detailed comparison with modern calculations of quasi-elastic spin-dependent scattering on the deuteron. A second experimental program with CLAS uses the technique of ``spectator tagging'' to extract the unpolarized structure functions of the neutron with minimal uncertainties from nuclear effects. By mapping out the dependence of the cross section on the ``spectator'' momentum, we can learn about final state interactions between the struck nucleon and the spectator, as well as modifications of the neutron structure due to nuclear binding. I will present preliminary results from the ``BoNuS'' experiment which pushed the detection limit of the spectator proton down to momenta of 70 MeV/c, where nuclear corrections should become small.

Pliocene to Recent Tectonic Activity of the Reşadiye Peninsula and the Relationship Between the Recent Earthquakes Occurred in the Gulf of Gökova: Preliminary Results.

NASA Astrophysics Data System (ADS)

Kahraman, Burcu; Özsayın, Erman; Üner, Serkan; Dirik, Kadir

2013-04-01

The E-W trending Reşadiye peninsula located at the southwestern part of the Anatolian Plate is an important horst developed between Gökova and Hisarönü Grabens. NW-trending the Datça Graben is the prominent structure comprising on the Reşadiye peninsula and records the significant fingerprints of palaeogeographical and kinematical characteristics from Pliocene to recent. The Datça Graben is controlled by NW-trending the Karaköy fault in the south and E-W trending the Kızlan fault in the north. Basement rocks of the graben are composed of ophiolitic rocks of the Lycian Nappes and Jurassic marine carbonates. The basinfill initiates with Early Pliocene Kızılaǧaç formation consisting conglomerates and continues with transgressive sequence (Yıldırımlı formation) composed of conglomerates, sandstones and marls with ignimbrite intercalations. Late Pliocene age was attributed to this formation based on the gastropoda and pelecypoda fauna according to previous studies. These units are unconformably overlain by Quaternary Karaköy formation consisting red blocky conglomerates. Pyroclastics of Quaternary age (161 ka) cover the older units. Alluvium, alluvial fan deposits and terrace deposits are the youngest units of the study area. To state the tectonic evolution of the Datça Graben, bedding planes and palaeostress analysis of the fault-slip data were used. The palaeostress analyses of the Kızlan fault clearly represent N-S tensional stress regime with pure normal fault characteristics. Due to the thick colluvium and alluvial fans, any fault-slip data were collected from the Karaköy fault. Considering the same stress regime is viable for the southwestern margin of the graben, fault planes ought to have normal fault characteristics with minor strike-slip component. SW-dipping bedding planes and SW-bearing palaeocurrent measurements show that Karaköy fault occurred before the Kızlan fault and the basin was first formed as a half-graben during Early

Preliminary Results of NASA's First Autonomous Formation Flying Experiment: Earth Observing-1 (EO-1)

NASA Technical Reports Server (NTRS)

Folta, David; Hawkins, Albin

2001-01-01

NASA's first autonomous formation flying mission is completing a primary goal of demonstrating an advanced technology called enhanced formation flying. To enable this technology, the Guidance, Navigation, and Control center at the Goddard Space Flight Center has implemented an autonomous universal three-axis formation flying algorithm in executive flight code onboard the New Millennium Program's (NMP) Earth Observing-1 (EO-1) spacecraft. This paper describes the mathematical background of the autonomous formation flying algorithm and the onboard design and presents the preliminary validation results of this unique system. Results from functionality assessment and autonomous maneuver control are presented as comparisons between the onboard EO-1 operational autonomous control system called AutoCon(tm), its ground-based predecessor, and a stand-alone algorithm.

Formation of gullies on Mars: Link to recent climate history and insolation microenvironments implicate surface water flow origin

PubMed Central

Head, James W.; Marchant, David R.; Kreslavsky, Mikhail A.

2008-01-01

Features seen in portions of a typical midlatitude Martian impact crater show that gully formation follows a geologically recent period of midlatitude glaciation. Geological evidence indicates that, in the relatively recent past, sufficient snow and ice accumulated on the pole-facing crater wall to cause glacial flow and filling of the crater floor with debris-covered glaciers. As glaciation waned, debris-covered glaciers ceased flowing, accumulation zones lost ice, and newly exposed wall alcoves continued as the location for limited snow/frost deposition, entrapment, and preservation. Analysis of the insolation geometry of this pole-facing crater wall, and similar occurrences in other craters at these latitudes on Mars, shows that they are uniquely favored for accumulation of snow and ice, and a relatively more rapid exposure to warmer summer temperatures. We show that, after the last glaciation, melting of residual snow and ice in alcoves could have formed the fluvial channels and sedimentary fans of the gullies. Recent modeling shows that top-down melting can occur in these microenvironments under conditions similar to those currently observed on Mars, if small amounts of snow or frost accumulate in alcoves and channels. Accumulation and melting is even more favored in the somewhat wetter, relatively recent geological past of Mars, after the period of active glaciation. PMID:18725636

Steps Toward Identifying PAHs: A Child's Garden of Recent Results

NASA Technical Reports Server (NTRS)

Hudgins, Douglas M.

2005-01-01

Based on over two decades of experimental, observational and theoretical studies by scientists around the world. It is now widely accepted that the composite emission of mixtures of vibrationally-excited PAHs and PAH ions can accommodate the general pattern of band positions, intensities, and profiles observed in the discreet IR emission features of carbon-rich interstellar dust, as well as the variations in those characteristics. These variations provide insight into the detailed nature of the emitting PAH population and reflect conditions within the emitting regions giving the population enormous potential as probes of astrophysical environments. Moreover, the ubiquity and abundance of this material has impacts that extend well beyond the IR. In this presentation we will examine recent, combined experimental, theoretical, and observational studies that indicate that nitrogen-substituted PAHs represent an important component of the interstellar dust population, and we will go on to explore some of the ramifications of this result. We will also explore the results of recent experimental studies of the strong, low-lying electronic transitions of ionized PAH ions in the Near-IR (0.7 - 2.5 microns) and explore the role that these transitions might play in pumping the PAH IR emission in regions of low-excitation.

The Askaryan Radio Array: Overview and Recent Results

NASA Astrophysics Data System (ADS)

Pfendner, Carl; Askaryan Radio Array (ARA) Collaboration

2017-01-01

The Askaryan Radio Array (ARA) is radio frequency observatory under construction at the South Pole that is searching for ultrahigh energy neutrinos via the Askaryan effect. By instrumenting several gigatons of Antarctic glacial ice, the experiment aims to detect a flux of neutrinos above 10 PeV in energy. The measurement of this expected flux of neutrinos would provide information about the highest energy processes in the universe with no local horizon. The full detector consisting of 37 stations is being constructed in a phased deployment with 3 stations already in place and two more planned for deployment in the 2017-2018 season. Recent results from an analysis of data from two stations and a search for neutrinos correlated with gamma ray bursts are presented here. Funding provided by NSF CAREER Award 1255557, NSF ARA Grant 1404266, BigData Grant 1250720.

Recent results from TRISTAN

DOE Office of Scientific and Technical Information (OSTI.GOV)

Enomoto, Ryoji

1997-01-01

TRISTAN results on {gamma}{gamma} physics from 1994 to 1995 are reviewed in this report. We have systematically investigated jet production, the {gamma}-structure function, and charm pair production in {gamma}{gamma} processes. The results are discussed, and future prospects are presented.

Cosmic ray measurements with LOPES: Status and recent results

NASA Astrophysics Data System (ADS)

Schröder, F. G.; Apel, W. D.; Arteaga-Velázquez, J. C.; Bähren, L.; Bekk, K.; Bertaina, M.; Biermann, P. L.; Blümer, J.; Bozdog, H.; Brancus, I. M.; Chiavassa, A.; Daumiller, K.; de Souza, V.; Di Pierro, F.; Doll, P.; Engel, R.; Falcke, H.; Fuchs, B.; Fuhrmann, D.; Gemmeke, H.; Grupen, C.; Haungs, A.; Heck, D.; Hörandel, J. R.; Horneffer, A.; Huber, D.; Huege, T.; Isar, P. G.; Kampert, K.-H.; Kang, D.; Krömer, O.; Kuijpers, J.; Link, K.; Łuczak, P.; Ludwig, M.; Mathes, H. J.; Melissas, M.; Morello, C.; Oehlschläger, J.; Palmieri, N.; Pierog, T.; Rautenberg, J.; Rebel, H.; Roth, M.; Rühle, C.; Saftoiu, A.; Schieler, H.; Schmidt, A.; Sima, O.; Toma, G.; Trinchero, G. C.; Weindl, A.; Wochele, J.; Zabierowski, J.; Zensus, J. A.

2013-05-01

LOPES is a digital antenna array at the Karlsruhe Institute of Technology, Germany, for cosmic-ray air-shower measurements. Triggered by the co-located KASCADE-Grande air-shower array, LOPES detects the radio emission of air showers via digital radio interferometry. We summarize the status of LOPES and recent results. In particular, we present an update on the reconstruction of the primary-particle properties based on almost 500 events above 100PeV. With LOPES, the arrival direction can be reconstructed with a precision of at least 0.65°, and the energy with a precision of at least 20%, which, however, does not include systematic uncertainties on the absolute energy scale. For many particle and astrophysics questions the reconstruction of the atmospheric depth of the shower maximum, Xmax, is important, since it yields information on the type of the primary particle and its interaction with the atmosphere. Recently, we found experimental evidence that the slope of the radio lateral distribution is indeed sensitive to the longitudinal development of the air shower, but unfortunately, the Xmax precision at LOPES is limited by the high level of anthropogenic radio background. Nevertheless, the developed methods can be transferred to next generation experiments with lower background, which should provide an Xmax precision competitive to other detection technologies.

Generic Community System Specification: A Proposed Format for Reporting the Results of Microgrid Optimization Analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jimenez, Antonio

This document provides a proposed format for reporting the results of microgrid optimization analysis. While the proposed format assumes that the modeling is conducted as part of a renewable energy retrofit of an existing diesel micro-grid, the format can certainly be adopted for other situations.

Recent results from DAMA/LIBRA - phase1 and perspectives

NASA Astrophysics Data System (ADS)

Bernabei, R.; Belli, P.; d'Angelo, S.; Di Marco, A.; Montecchia, F.; d'Angelo, A.; Incicchitti, A.; Cappella, F.; Caracciolo, V.; Cerulli, R.; Dai, C. J.; He, H. L.; Kuang, H. H.; Ma, X. H.; Sheng, X. D.; Wang, R. G.; Ye, Z. P.

The DAMA/LIBRA{phase1 and the former DAMA/NaI data (cumulative exposure 1:33 ton x yr, corresponding to 14 annual cycles) give evidence at 9.3 σ C.L. for the presence of Dark Matter (DM) particles in the galactic halo, on the basis of the exploited model independent DM annual modulation signature by using highly radiopure NaI(Tl) target. Results and comparisons will be briefly recalled. Recent analyses on possible diurnal ects and on the Earth shadowing effect (the latter holds only for some DM candidates) will be mentioned. Finally, the perspectives of the running DAMA/LIBRA-phase2 will be mentioned.

Dynamics of Nanoparticle-Protein Corona Complex Formation: Analytical Results from Population Balance Equations

PubMed Central

Darabi Sahneh, Faryad; Scoglio, Caterina; Riviere, Jim

2013-01-01

Background Nanoparticle-protein corona complex formation involves absorption of protein molecules onto nanoparticle surfaces in a physiological environment. Understanding the corona formation process is crucial in predicting nanoparticle behavior in biological systems, including applications of nanotoxicology and development of nano drug delivery platforms. Method This paper extends the modeling work in to derive a mathematical model describing the dynamics of nanoparticle corona complex formation from population balance equations. We apply nonlinear dynamics techniques to derive analytical results for the composition of nanoparticle-protein corona complex, and validate our results through numerical simulations. Results The model presented in this paper exhibits two phases of corona complex dynamics. In the first phase, proteins rapidly bind to the free surface of nanoparticles, leading to a metastable composition. During the second phase, continuous association and dissociation of protein molecules with nanoparticles slowly changes the composition of the corona complex. Given sufficient time, composition of the corona complex reaches an equilibrium state of stable composition. We find analytical approximate formulae for metastable and stable compositions of corona complex. Our formulae are very well-structured to clearly identify important parameters determining corona composition. Conclusion The dynamics of biocorona formation constitute vital aspect of interactions between nanoparticles and living organisms. Our results further understanding of these dynamics through quantitation of experimental conditions, modeling results for in vitro systems to better predict behavior for in vivo systems. One potential application would involve a single cell culture medium related to a complex protein medium, such as blood or tissue fluid. PMID:23741371

Dynamics of nanoparticle-protein corona complex formation: analytical results from population balance equations.

PubMed

Darabi Sahneh, Faryad; Scoglio, Caterina; Riviere, Jim

2013-01-01

Nanoparticle-protein corona complex formation involves absorption of protein molecules onto nanoparticle surfaces in a physiological environment. Understanding the corona formation process is crucial in predicting nanoparticle behavior in biological systems, including applications of nanotoxicology and development of nano drug delivery platforms. This paper extends the modeling work in to derive a mathematical model describing the dynamics of nanoparticle corona complex formation from population balance equations. We apply nonlinear dynamics techniques to derive analytical results for the composition of nanoparticle-protein corona complex, and validate our results through numerical simulations. The model presented in this paper exhibits two phases of corona complex dynamics. In the first phase, proteins rapidly bind to the free surface of nanoparticles, leading to a metastable composition. During the second phase, continuous association and dissociation of protein molecules with nanoparticles slowly changes the composition of the corona complex. Given sufficient time, composition of the corona complex reaches an equilibrium state of stable composition. We find analytical approximate formulae for metastable and stable compositions of corona complex. Our formulae are very well-structured to clearly identify important parameters determining corona composition. The dynamics of biocorona formation constitute vital aspect of interactions between nanoparticles and living organisms. Our results further understanding of these dynamics through quantitation of experimental conditions, modeling results for in vitro systems to better predict behavior for in vivo systems. One potential application would involve a single cell culture medium related to a complex protein medium, such as blood or tissue fluid.

Recent Borexino results and prospects for the near future

NASA Astrophysics Data System (ADS)

D'Angelo, D.; Agostini, M.; Altenmüller, K.; Appel, S.; Bellini, G.; Benziger, J.; Bick, D.; Bonfini, G.; Bravo, D.; Caccianiga, B.; Calaprice, F.; Caminata, A.; Cavalcante, P.; Chepurnov, A.; Davini, S.; Derbin, A.; Di Noto, L.; Drachnev, I.; Etenko, A.; Fomenko, K.; Franco, D.; Gabriele, F.; Galbiati, C.; Ghiano, C.; Giammarchi, M.; Goeger-Neff, M.; Goretti, A.; Gromov, M.; Hagner, C.; Hungerford, E.; Ianni, Aldo; Ianni, Andrea; Jedrzejczak, K.; Kaiser, M.; Kobychev, V.; Korablev, D.; Korga, G.; Kryn, D.; Laubenstein, M.; Lehnert, B.; Litvinovich, E.; Lombardi, F.; Lombardi, P.; Ludhova, L.; Lukyanchenko, G.; Machulin, I.; Manecki, S.; Maneschg, W.; Marcocci, S.; Meroni, E.; Meyer, M.; Miramonti, L.; Misiaszek, M.; Montuschi, M.; Mosteiro, P.; Muratova, V.; Neumair, B.; Oberauer, L.; Obolensky, M.; Ortica, F.; Pallavicini, M.; Papp, L.; Perasso, L.; Pocar, A.; Ranucci, G.; Razeto, A.; Re, A.; Romani, A.; Roncin, R.; Rossi, N.; Schönert, S.; Semenov, D.; Simgen, H.; Skorokhvatov, M.; Smirnov, O.; Sotnikov, A.; Sukhotin, S.; Suvorov, Y.; Tartaglia, R.; Testera, G.; Thurn, J.; Toropova, M.; Unzhakov, E.; Vishneva, A.; Vogelaar, R. B.; von Feilitzsch, F.; Wang, H.; Weinz, S.; Winter, J.; Wojcik, M.; Wurm, M.; Yokley, Z.; Zaimidoroga, O.; Zavatarelli, S.; Zuber, K.; Zuzel, G.

2016-11-01

The Borexino experiment located in the Gran Sasso National Laboratory, is an organic liquid scintillator detector conceived for the real time spectroscopy of low energy solar neutrinos. The phase-I of the data taking campaign (2007 - 2010) has allowed the first independent measurements of 7Be and pep solar neutrino fluxes as well as the first measurement of anti-neutrinos from the Earth. After a purification of the scintillator, Borexino is now in phase-II since 2011. Thanks to the unprecedented background levels, we have performed the first flux measurement of neutrinos from the fundamental pp reaction which powers the Sun. We review this breakthrough result and other recent results, including the latest review of our terrestrial neutrino analysis. We also discuss the upcoming measurements on middle energy solar neutrino spectral components (pep, CNO) and the new project SOX devoted to the study of sterile neutrinos via the use of a neutrino source placed in close proximity of the detector's active material.

Recent QCD Results from NuTeV/CCFR Collaboration

NASA Astrophysics Data System (ADS)

Adams, T.; Alton, A.; Arroyo, C. G.; Avvakumov, S.; de Barbaro, L.; de Barbaro, P.; Bazarko, A. O.; Bernstein, R. H.; Bodek, A.; Bolton, T.; Brau, J.; Buchholz, D.; Budd, H.; Bugel, L.; Conrad, J. M.; Drucker, R. B.; Formaggio, J. A.; Frey, R.; Goldman, J.; Goncharov, M.; Harris, D. A.; Johnson, R. A.; Kim, J. H.; King, B. J.; Kinnel, T.; Koutsoliotas, S.; Lamm, M. J.; Marsh, W.; Mason, D.; McFarland, K. S.; McNulty, C.; Mishra, S. R.; Naples, D.; Nienaber, P.; Romosan, A.; Sakumoto, W. K.; Schellman, H. M.; Sculli, F. J.; Seligman, W. G.; Shaevitz, M. H.; Smith, W. H.; Spentzouris, P.; Stern, E. G.; Tamminga, B. M.; Vakili, M.; Vaitaitis, A.; Wu, V.; Yang, U. K.; Yu, J.; Zeller, G. P.

2000-06-01

Fermilab experiments CCFR and its successor NuTeV study nucleon structure through deep inelastic scattering of neutrino beams off an iron target. We report on the most recent CCFR measurement of the νN differential cross section and resulting structure functions ΔxF 3 = xF ν3 - xF overlineν3, and R long = {σ L}/{σ T}, in the framework of massive charm quark. ΔxF3 in sensitive to strange and charm content of the nucleon. NuTeV's preliminary direct measurement of the strange sea, from dimuon charged-current production, and nucleon charm content probed by neutral-current νN interaction, are also presented.

The Focusing Optics X-ray Solar Imager: Second Flight and Recent Results

NASA Astrophysics Data System (ADS)

Christe, S.; Krucker, S.; Glesener, L.; Ishikawa, S. N.; Ramsey, B.; Buitrago Casas, J. C.; Foster, N.

2014-12-01

Solar flares accelerate particles up to high energies through various acceleration mechanisms which are not currently understood. Hard X-rays are the most direct diagnostic of flare-accelerated electrons. However past and current hard x-ray observation lack the sensitivity and dynamic range necessary to observe the faint signature of accelerated electrons in the acceleration region, the solar corona. These limitations can be easily overcome through the use of HXR focusing optics coupled with solid state pixelated detectors. We present on recent updates on the FOXSI sounding rocket program. During its first flight FOXSI observed imaged a microflare with simultaneous observations by RHESSI. We present recent imaging analysis of the FOXSI observations and detailed comparison with RHESSI. New detector calibration results are also presented and, time-permitting, preliminary results from the second launch of FOXSI scheduled for December 2014.

[Targeted therapies in hepatocellular carcinomas: recent results and future development].

PubMed

Marijon, H; Faivre, S; Raymond, E

2009-05-01

Hepatocellular carcinoma (HCC) is one of the 5th most common cancers around the world with a limited number of systemic therapeutic options. Cytotoxic agents, hormonotherapy and immunotherapy have failed to demonstrate benefit compared to best supportive care in patients with advanced HCC. The recent development of targeted therapies provided hope for the treatment of advanced HCC. We reviewed phases II-III trials presented in 2007 and 2008. Results are promising with a clinical benefit reported with molecular therapies targeting EGF/EGFR and VEGF/VEGFR pathways.

Overview of Recent DIII-D Experimental Results

NASA Astrophysics Data System (ADS)

Fenstermacher, Max; DIII-D Team

2017-10-01

Recent DIII-D experiments contributed to the ITER physics basis and to physics understanding for extrapolation to future devices. A predict-first analysis showed how shape can enhance access to RMP ELM suppression. 3D equilibrium changes from ELM control RMPs, were linked to density pumpout. Ion velocity imaging in the SOL showed 3D C2+flow perturbations near RMP induced n =1 islands. Correlation ECE reveals a 40% increase in Te turbulence during QH-mode and 70% during RMP ELM suppression vs. ELMing H-mode. A long-lived predator-prey oscillation replaces edge MHD in recent low-torque QH-mode plasmas. Spatio-temporally resolved runaway electron measurements validate the importance of synchrotron and collisional damping on RE dissipation. A new small angle slot divertor achieves strong plasma cooling and facilitates detachment access. Fast ion confinement was improved in high q_min scenarios using variable beam energy optimization. First reproducible, stable ITER baseline scenarios were established. Studies have validated a model for edge momentum transport that predicts the pedestal main-ion intrinsic velocity value and direction. Work supported by the US DOE under DE-FC02-04ER54698 and DE-AC52-07NA27344.

Highlights of recent results from the VERITAS gamma-ray observatory

NASA Astrophysics Data System (ADS)

Fortson, Lucy; VERITAS Collaboration

2016-05-01

VERITAS is a major ground-based gamma-ray observatory comprising an array of four 12 meter air Cherenkov telescopes operating at the Fred Lawrence Whipple Observatory near Tucson, Arizona. Data taking has continued from 2007 with a major camera upgrade completed in 2012 resulting in the current sensitivity to very-high-energy (VHE) gamma rays between 85 GeV and 30 TeV. VERITAS has detected 54 sources (half of which have been discoveries) leading to many significant contributions to the field of VHE astronomy. These proceedings highlight some of the more recent VERITAS results from the blazar and galactic observing programs as well as measurements of the cosmic-ray electron spectrum, constraints on dark matter and a follow-up program for astrophysical neutrinos.

HIV surveillance in MENA: recent developments and results

PubMed Central

Bozicevic, Ivana; Riedner, Gabriele; Calleja, Jesus Maria Garcia

2013-01-01

Objectives To provide an overview of the current level of development and results from the national HIV surveillance systems of the 23 countries of the Middle East and North Africa (MENA), and to assess the quality of HIV surveillance systems in the period 2007–2011. Methods A questionnaire was used to collect the information about the structure, activities and the results of HIV surveillance systems from the National AIDS Programmes. Assessment of the quality was based on four indicators: timeliness of data collection, appropriateness of populations under surveillance, consistency of the surveillance sites and groups measured over time, and coverage of the surveillance system. Results Only in four countries did surveillance systems enable assessment of epidemic trends in the same populations and locations over time, such as in pregnant women (Morocco, Iran), injecting drug users (Iran, Pakistan), female sex workers (Djibouti, Morocco) and male sex workers (Pakistan). There is increasing evidence of HIV infection being firmly established in at least one of the populations most at risk of HIV in nine MENA countries, while lower risk populations show elevated HIV prevalence in South Sudan, Djibouti and some parts of Somalia. Conclusions The performance of HIV surveillance systems in several of the MENA countries has improved in recent years. The extent of HIV epidemics in the populations most at risk of HIV is still largely unknown in 10 countries. Multiple data sources that most of the countries still lack would enable indirectly estimation not only of the patterns of HIV epidemics but also the effectiveness of HIV responses. PMID:23434789

Gully formation on Mars: Two recent phases of formation suggested by links between morphology, slope orientation and insolation history

NASA Astrophysics Data System (ADS)

Morgan, Gareth A.; Head, James W.; Forget, François; Madeleine, Jean-Baptiste; Spiga, Aymeric

2010-08-01

The unusual 80 km diameter Noachian-aged Asimov crater in Noachis Terra (46°S, 5°E) is characterized by extensive Noachian-Hesperian crater fill and a younger superposed annulus of valleys encircling the margins of the crater floor. These valleys provide an opportunity to study the relationships of gully geomorphology as a function of changing slope orientation relative to solar insolation. We found that the level of development of gullies was highly correlated with slope orientation and solar insolation. The largest and most complex gully systems, with the most well-developed fluvial landforms, are restricted to pole-facing slopes. In contrast, gullies on equator-facing slopes are smaller, more poorly developed and integrated, more highly degraded, and contain more impact craters. We used a 1D version of the Laboratoire de Météorologie Dynamique GCM, and slope geometries (orientation and angle), driven by predicted spin-axis/orbital parameter history, to assess the distribution and history of surface temperatures in these valleys during recent geological history. Surface temperatures on pole-facing slopes preferential for water ice accumulation and subsequent melting are predicted to occur as recently as 0.5-2.1 Ma, which is consistent with age estimates of gully activity elsewhere on Mars. In contrast, the 1D model predicts that water ice cannot accumulate on equator-facing slopes until obliquities exceed 45°, suggesting they are unlikely to have been active over the last 5 Ma. The correlation of the temperature predictions and the geological evidence for age differences suggests that there were two phases of gully formation in the last few million years: an older phase in which top-down melting occurred on equator-facing slopes and a younger more robust phase on pole-facing slopes. The similarities of small-scale fluvial erosion features seen in the gullies on Mars and those observed in gullies cut by seasonal and perennial snowmelt in the Antarctic Dry

Recent results of the Defect-Induced Mix Experiments (DIME) on NIF

NASA Astrophysics Data System (ADS)

Schmitt, M. J.; Bradley, P. A.; Cobble, J. A.; Hakel, P.; Hsu, S. C.; Krasheninnikova, N. S.; Kyrala, G. A.; Murphy, T. J.; Obrey, K. A.; Shah, R. C.; Tregillis, I. L.; Craxton, S. C.; McKenty, P. W.; Mancini, R. C.; Johns, H. M.; Joshi, Tirtha; Mayes, Daniel

2012-10-01

Investigations of directly driven implosions have been performed including experiments on Omega, and more recently NIF, to deduce the extent and uniformity of 4π and defect-induced mix near the shell/gas interface of plastic (CH) capsules filled with 5 atm D2 gas. Imaging diagnostics are used to measure the spatial variation of mix caused by the growth of non-uniformities in both capsule and laser drive characteristics. Thin (2μm) layers containing 1-2% (atomic) mid-Z dopants are imaged spectrally at late time in the implosion using multiple monochromatic imaging of H-like and He-like atomic line emission. Areal image backlighting of the capsules provides both r(t) and the symmetry of the implosion. Recent results will be shown including inferred 4π mix width, laser imprint induced mix, and mix from capsule variations.

Collapsed state of polyglutamic acid results in amyloid spherulite formation

PubMed Central

Stehli, Daniel; Mulaj, Mentor; Miti, Tatiana; Traina, Joshua; Foley, Joseph; Muschol, Martin

2015-01-01

Self-assembly of proteins and peptides into amyloid fibrils involves multiple distinct intermediates and late-stage fibrillar polymorphs. Understanding the conditions and mechanisms that promote the formation of one type of intermediate and polymorph over the other represents a fundamental challenge. Answers to this question are also of immediate biomedical relevance since different amyloid aggregate species have been shown to have distinct pathogenic potencies. One amyloid polymorph that has received comparatively little attention are amyloid spherulites. Here we report that self-assembly of the intrinsically disordered polymer poly(L-glutamic) acid (PLE) can generate amyloid spherulites. We characterize spherulite growth kinetics, as well as the morphological, optical and tinctorial features of this amyloid polymorph previously unreported for PLE. We find that PLE spherulites share both tinctorial and structural characteristics with their amyloid fibril counterparts. Differences in PLE's molecular weight, polydispersity or chemistry could not explain the selective propensity toward either fibril or spherulite formation. Instead, we provide evidence that PLE polymers can exist in either a collapsed globule or an extended random coil conformation. The collapsed globule consistently produces spherulites while the extended coil assembles into disordered fibril bundles. This results suggests that these 2 PLE conformers directly affect the morphology of the resulting macroscopic amyloid assembly. PMID:28232889

Collapsed state of polyglutamic acid results in amyloid spherulite formation.

PubMed

Stehli, Daniel; Mulaj, Mentor; Miti, Tatiana; Traina, Joshua; Foley, Joseph; Muschol, Martin

2015-01-01

Self-assembly of proteins and peptides into amyloid fibrils involves multiple distinct intermediates and late-stage fibrillar polymorphs. Understanding the conditions and mechanisms that promote the formation of one type of intermediate and polymorph over the other represents a fundamental challenge. Answers to this question are also of immediate biomedical relevance since different amyloid aggregate species have been shown to have distinct pathogenic potencies. One amyloid polymorph that has received comparatively little attention are amyloid spherulites. Here we report that self-assembly of the intrinsically disordered polymer poly(L-glutamic) acid (PLE) can generate amyloid spherulites. We characterize spherulite growth kinetics, as well as the morphological, optical and tinctorial features of this amyloid polymorph previously unreported for PLE. We find that PLE spherulites share both tinctorial and structural characteristics with their amyloid fibril counterparts. Differences in PLE's molecular weight, polydispersity or chemistry could not explain the selective propensity toward either fibril or spherulite formation. Instead, we provide evidence that PLE polymers can exist in either a collapsed globule or an extended random coil conformation. The collapsed globule consistently produces spherulites while the extended coil assembles into disordered fibril bundles. This results suggests that these 2 PLE conformers directly affect the morphology of the resulting macroscopic amyloid assembly.

Phototropic bending of non-elongating and radially growing woody stems results from asymmetrical xylem formation.

PubMed

Matsuzaki, Jun; Masumori, Masaya; Tange, Takeshi

2007-05-01

Active phototropic bending of non-elongating and radially growing portion of stems (woody stems) has not been previously documented, whereas negative gravitropic bending is well known. We found phototropic bending in woody stems and searched for the underlying mechanism. We inclined 1-year-old Quercus crispula Blume seedlings and unilaterally illuminated them from a horizontal direction perpendicular to ('normal' illumination) or parallel to ('parallel' illumination) the inclination azimuth. With normal illumination, active phototropic bending and xylem formation could be evaluated separately from the negative gravitropic response and vertical deflection resulting from the weight of the seedlings. One-year-old stems with normal illumination bent significantly, with asymmetrical xylem formation towards the illuminated upper surface and side of the stem, whereas those with parallel illumination showed non-significant lateral bending, with asymmetrical xylem formation only on the upper side. A mechanical model was built on the assumption that a bending moment resulted from the asymmetrical xylem formation during phototropic bending of the woody stems. The model fitted the relationship between the observed spatial distributions of the xylem and the observed lateral bending, and thus supported the hypothesis that phototropic bending of woody stems results from asymmetrical xylem formation, as such occurs during gravitropism.

STAR FORMATION IN DISK GALAXIES. III. DOES STELLAR FEEDBACK RESULT IN CLOUD DEATH?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tasker, Elizabeth J.; Wadsley, James; Pudritz, Ralph

2015-03-01

Stellar feedback, star formation, and gravitational interactions are major controlling forces in the evolution of giant molecular clouds (GMCs). To explore their relative roles, we examine the properties and evolution of GMCs forming in an isolated galactic disk simulation that includes both localized thermal feedback and photoelectric heating. The results are compared with the three previous simulations in this series, which consists of a model with no star formation, star formation but no form of feedback, and star formation with photoelectric heating in a set with steadily increasing physical effects. We find that the addition of localized thermal feedback greatlymore » suppresses star formation but does not destroy the surrounding GMC, giving cloud properties closely resembling the run in which no stellar physics is included. The outflows from the feedback reduce the mass of the cloud but do not destroy it, allowing the cloud to survive its stellar children. This suggests that weak thermal feedback such as the lower bound expected for a supernova may play a relatively minor role in the galactic structure of quiescent Milky-Way-type galaxies, compared to gravitational interactions and disk shear.« less

Recent results from the SIMECA code and VLTI observations

NASA Astrophysics Data System (ADS)

Meilland, A.; Stee, Ph.

We present recent results on active hot stars using the first VLTI/MIDI and VLTI/AMBER observations, and the SIMECA code developed by Stee (1994). α Arae was the first classical Be star observed with MIDI (June 2003) and AMBER (February 2005). The size of its circumstellar envelope was measured and thanks to the spectrally-resolved interferometric AMBER observations, we were able, for the first time to evidence the Keplerian rotation of the circumstellar disc. MWC 297 is one of the brightest Herbig Be star, and it was then observed during the first commissioning run of AMBER in May 2004. The data obtained were good enough to allow us to infer the accretion disc extension, as well as to put strong constraints on the stellar wind geometry and kinematics.

Dynamical Electroweak Symmetry Breaking with a Heavy Fermion in Light of Recent LHC Results

DOE PAGES

Hung, Pham Q.

2013-01-01

The recent announcement of a discovery of a possible Higgs-like particle—its spin and parity are yet to be determined—at the LHC with a mass of 126 GeV necessitates a fresh look at the nature of the electroweak symmetry breaking, in particular if this newly-discovered particle will turn out to have the quantum numbers of a Standard Model Higgs boson. Even if it were a 0 + scalar with the properties expected for a SM Higgs boson, there is still the quintessential hierarchy problem that one has to deal with and which, by itself, suggests a new physics energy scale around 1 TeV.more » This paper presents a minireview of one possible scenario: the formation of a fermion-antifermion condensate coming from a very heavy fourth generation, carrying the quantum number of the SM Higgs field, and thus breaking the electroweak symmetry.« less

Communicating patient-reported outcome scores using graphic formats: results from a mixed-methods evaluation.

PubMed

Brundage, Michael D; Smith, Katherine C; Little, Emily A; Bantug, Elissa T; Snyder, Claire F

2015-10-01

Patient-reported outcomes (PROs) promote patient-centered care by using PRO research results ("group-level data") to inform decision making and by monitoring individual patient's PROs ("individual-level data") to inform care. We investigated the interpretability of current PRO data presentation formats. This cross-sectional mixed-methods study randomized purposively sampled cancer patients and clinicians to evaluate six group-data or four individual-data formats. A self-directed exercise assessed participants' interpretation accuracy and ratings of ease-of-understanding and usefulness (0 = least to 10 = most) of each format. Semi-structured qualitative interviews explored helpful and confusing format attributes. We reached thematic saturation with 50 patients (44 % < college graduate) and 20 clinicians. For group-level data, patients rated simple line graphs highest for ease-of-understanding and usefulness (median 8.0; 33 % selected for easiest to understand/most useful) and clinicians rated simple line graphs highest for ease-of-understanding and usefulness (median 9.0, 8.5) but most often selected line graphs with confidence limits or norms (30 % for each format for easiest to understand/most useful). Qualitative results support that clinicians value confidence intervals, norms, and p values, but patients find them confusing. For individual-level data, both patients and clinicians rated line graphs highest for ease-of-understanding (median 8.0 patients, 8.5 clinicians) and usefulness (median 8.0, 9.0) and selected them as easiest to understand (50, 70 %) and most useful (62, 80 %). The qualitative interviews supported highlighting scores requiring clinical attention and providing reference values. This study has identified preferences and opportunities for improving on current formats for PRO presentation and will inform development of best practices for PRO presentation. Both patients and clinicians prefer line graphs across group-level data and individual

The mzTab Data Exchange Format: Communicating Mass-spectrometry-based Proteomics and Metabolomics Experimental Results to a Wider Audience*

PubMed Central

Griss, Johannes; Jones, Andrew R.; Sachsenberg, Timo; Walzer, Mathias; Gatto, Laurent; Hartler, Jürgen; Thallinger, Gerhard G.; Salek, Reza M.; Steinbeck, Christoph; Neuhauser, Nadin; Cox, Jürgen; Neumann, Steffen; Fan, Jun; Reisinger, Florian; Xu, Qing-Wei; del Toro, Noemi; Pérez-Riverol, Yasset; Ghali, Fawaz; Bandeira, Nuno; Xenarios, Ioannis; Kohlbacher, Oliver; Vizcaíno, Juan Antonio; Hermjakob, Henning

2014-01-01

The HUPO Proteomics Standards Initiative has developed several standardized data formats to facilitate data sharing in mass spectrometry (MS)-based proteomics. These allow researchers to report their complete results in a unified way. However, at present, there is no format to describe the final qualitative and quantitative results for proteomics and metabolomics experiments in a simple tabular format. Many downstream analysis use cases are only concerned with the final results of an experiment and require an easily accessible format, compatible with tools such as Microsoft Excel or R. We developed the mzTab file format for MS-based proteomics and metabolomics results to meet this need. mzTab is intended as a lightweight supplement to the existing standard XML-based file formats (mzML, mzIdentML, mzQuantML), providing a comprehensive summary, similar in concept to the supplemental material of a scientific publication. mzTab files can contain protein, peptide, and small molecule identifications together with experimental metadata and basic quantitative information. The format is not intended to store the complete experimental evidence but provides mechanisms to report results at different levels of detail. These range from a simple summary of the final results to a representation of the results including the experimental design. This format is ideally suited to make MS-based proteomics and metabolomics results available to a wider biological community outside the field of MS. Several software tools for proteomics and metabolomics have already adapted the format as an output format. The comprehensive mzTab specification document and extensive additional documentation can be found online. PMID:24980485

The mzTab data exchange format: communicating mass-spectrometry-based proteomics and metabolomics experimental results to a wider audience.

PubMed

Griss, Johannes; Jones, Andrew R; Sachsenberg, Timo; Walzer, Mathias; Gatto, Laurent; Hartler, Jürgen; Thallinger, Gerhard G; Salek, Reza M; Steinbeck, Christoph; Neuhauser, Nadin; Cox, Jürgen; Neumann, Steffen; Fan, Jun; Reisinger, Florian; Xu, Qing-Wei; Del Toro, Noemi; Pérez-Riverol, Yasset; Ghali, Fawaz; Bandeira, Nuno; Xenarios, Ioannis; Kohlbacher, Oliver; Vizcaíno, Juan Antonio; Hermjakob, Henning

2014-10-01

The HUPO Proteomics Standards Initiative has developed several standardized data formats to facilitate data sharing in mass spectrometry (MS)-based proteomics. These allow researchers to report their complete results in a unified way. However, at present, there is no format to describe the final qualitative and quantitative results for proteomics and metabolomics experiments in a simple tabular format. Many downstream analysis use cases are only concerned with the final results of an experiment and require an easily accessible format, compatible with tools such as Microsoft Excel or R. We developed the mzTab file format for MS-based proteomics and metabolomics results to meet this need. mzTab is intended as a lightweight supplement to the existing standard XML-based file formats (mzML, mzIdentML, mzQuantML), providing a comprehensive summary, similar in concept to the supplemental material of a scientific publication. mzTab files can contain protein, peptide, and small molecule identifications together with experimental metadata and basic quantitative information. The format is not intended to store the complete experimental evidence but provides mechanisms to report results at different levels of detail. These range from a simple summary of the final results to a representation of the results including the experimental design. This format is ideally suited to make MS-based proteomics and metabolomics results available to a wider biological community outside the field of MS. Several software tools for proteomics and metabolomics have already adapted the format as an output format. The comprehensive mzTab specification document and extensive additional documentation can be found online. © 2014 by The American Society for Biochemistry and Molecular Biology, Inc.

Some recent experimental results related to nuclear chirality

NASA Astrophysics Data System (ADS)

Timár, J.; Kuti, I.; Sohler, D.; Starosta, K.; Koike, T.; Paul, E. S.

2014-09-01

Detailed band structures of three chiral-candidate nuclei, 134Pr, 132La and 103Rh have been studied. The aim of the study was twofold. First, to try to explore the reasons behind the contradiction between the theoretically predicted chirality in these nuclei and the recently observed fingerprints that suggest non-chiral interpretation for the previous chiral candidate band doublets. Second, to search for multiple chiral bands of different types in these nuclei. In 134Pr a new πh11/2vh11/2 band has been observed besides the previously known chiral-candidate πh11/2vh11/2 doublet. This new band and the yrare πh11/2vh11/2 band show the expected features of a chiral doublet structure. This fact combined with the observed similarity between the band structures of 134Pr and 132La suggests that chirality might exist in these nuclei. The detailed study of the 103Rh band structure resulted in the observation of two new chiral-doublet looking structures besides the previously known one. This is indicative of possible existence of multiple chiral doublet structure in this nucleus.

Recent results from the strong interactions program of NA61/SHINE

NASA Astrophysics Data System (ADS)

Pulawski, Szymon

2017-12-01

The NA61/SHINE experiment studies hadron production in hadron+hadron, hadron+nucleus and nucleus+nucleus collisions. The strong interactions program has two main purposes: study the properties of the onset of deconfinement and search for the signatures of the critical point of strongly interacting matter. This aim is pursued by performing a two-dimensional scan of the phase diagram by varying the energy/momentum (13A-158A GeV/c) and the system size (p+p, Be+Be, Ar+Sc, Xe+La) of the collisions. This publication reviews recent results from p+p, Be+Be and Ar+Sc interactions. Measured particle spectra are discussed and compared to NA49 results from Pb+Pb collisions. The results illustrate the progress towards scanning the phase diagram of strongly interacting matter.

HIV surveillance in MENA: recent developments and results.

PubMed

Bozicevic, Ivana; Riedner, Gabriele; Calleja, Jesus Maria Garcia

2013-11-01

To provide an overview of the current level of development and results from the national HIV surveillance systems of the 23 countries of the Middle East and North Africa (MENA), and to assess the quality of HIV surveillance systems in the period 2007-2011. A questionnaire was used to collect the information about the structure, activities and the results of HIV surveillance systems from the National AIDS Programmes. Assessment of the quality was based on four indicators: timeliness of data collection, appropriateness of populations under surveillance, consistency of the surveillance sites and groups measured over time, and coverage of the surveillance system. Only in four countries did surveillance systems enable assessment of epidemic trends in the same populations and locations over time, such as in pregnant women (Morocco, Iran), injecting drug users (Iran, Pakistan), female sex workers (Djibouti, Morocco) and male sex workers (Pakistan). There is increasing evidence of HIV infection being firmly established in at least one of the populations most at risk of HIV in nine MENA countries, while lower risk populations show elevated HIV prevalence in South Sudan, Djibouti and some parts of Somalia. The performance of HIV surveillance systems in several of the MENA countries has improved in recent years. The extent of HIV epidemics in the populations most at risk of HIV is still largely unknown in 10 countries. Multiple data sources that most of the countries still lack would enable indirectly estimation not only of the patterns of HIV epidemics but also the effectiveness of HIV responses.

First Results from a Hardware-in-the-Loop Demonstration of Closed-Loop Autonomous Formation Flying

NASA Technical Reports Server (NTRS)

Gill, E.; Naasz, Bo; Ebinuma, T.

2003-01-01

A closed-loop system for the demonstration of formation flying technologies has been developed at NASA s Goddard Space Flight Center. Making use of a GPS signal simulator with a dual radio frequency outlet, the system includes two GPS space receivers as well as a powerful onboard navigation processor dedicated to the GPS-based guidance, navigation, and control of a satellite formation in real-time. The closed-loop system allows realistic simulations of autonomous formation flying scenarios, enabling research in the fields of tracking and orbit control strategies for a wide range of applications. A sample scenario has been set up where the autonomous transition of a satellite formation from an initial along-track separation of 800 m to a final distance of 100 m has been demonstrated. As a result, a typical control accuracy of about 5 m has been achieved which proves the applicability of autonomous formation flying techniques to formations of satellites as close as 50 m.

The MagAO Giant Accreting Protoplanet Survey (GAPlanetS): Recent Results

NASA Astrophysics Data System (ADS)

Follette, Katherine; Close, Laird; Males, Jared; Morzinski, Katie; Leonard, Clare; MagAO

2018-01-01

I will summarize recent results of the MagAO Giant Accreting Protoplant Survey (GAPlanetS), a search for accreting protoplanets at H-alpha inside of transitional disk gaps. These young, centrally-cleared circumstellar disks are often hosted by stars that are still actively accreting, making it likely that any planets that lie in their central cavities will also be actively accreting. Through differential imaging at Hydrogen-alpha using Magellan's visible light adaptive optics system, we have completed the first systematic search for H-alpha emission from accreting protoplanets in fifteen bright Southern hemisphere transitional disks. I will present results from this survey, including a second epoch on the LkCa 15 system that shows several accreting protoplanet candidates.

Blanking and piercing theory, applications and recent experimental results

NASA Astrophysics Data System (ADS)

Zaid, Adnan l. O.

2014-06-01

Blanking and piercing are manufacturing processes by which certain geometrical shapes are sheared off a sheet metal. If the sheared off part is the one required, the processes referred to as blanking and if the remaining part in the sheet is the one required, the process is referred to as piercing. In this paper, the theory and practice of these processes are reviewed and discussed The main parameters affecting these processes are presented and discussed. These include: the radial clearance percentage, punch and die geometrical parameters, for example punch and die profile radii. The abovementioned parameters on the force and energy required to effect blanking together with their effect on the quality of the products are also presented and discussed. Recent experimental results together with photomacrographs and photomicrographs are also included and discussed. Finally, the effect of punch and die wear on the quality of the blanks is alsogiven and discussed.

Reversible cluster formation in concentrated monoclonal antibody solutions

NASA Astrophysics Data System (ADS)

Godfrin, P. Douglas; Porcar, Lionel; Falus, Peter; Zarraga, Isidro; Wagner, Norm; Liu, Yun

2015-03-01

Protein cluster formation in solution is of fundamental interest for both academic research and industrial applications. Recently, industrial scientists are also exploring the effect of reversible cluster formation on biopharmaceutical processing and delivery. However, despite of its importance, the understanding of protein clusters at concentrated solutions remains scientifically very challenging. Using the neutron spin echo technique to study the short time dynamics of proteins in solutions, we have recently systematically studied cluster formation in a few monoclonal antibody (mAb) solutions and their relation with solution viscosity. We show that the existence of anisotropic attraction can cause the formation of finite sized clusters, which increases the solution viscosity. Interestingly, once clusters form at relatively low concentrations, the average size of clusters in solutions remains almost constant over a wide range of concentrations similar to that of micelle formation. For a different mAb we have also investigated, the attraction is mostly induced by hydrophobic patches. As a result, these mAbs form large clusters with loosely linked proteins. In both cases, the formation of clusters all increases the solution viscosity substantially. However, due to different physics origins of cluster formation, solutions viscosities for these two different types of mAbs need to be controlled by different ways.

A single mutation results in diploid gamete formation and parthenogenesis in a Drosophila yemanuclein-alpha meiosis I defective mutant

PubMed Central

2010-01-01

Background Sexual reproduction relies on two key events: formation of cells with a haploid genome (the gametes) and restoration of diploidy after fertilization. Therefore the underlying mechanisms must have been evolutionary linked and there is a need for evidence that could support such a model. Results We describe the identification and the characterization of yem1, the first yem-alpha mutant allele (V478E), which to some extent affects diploidy reduction and its restoration. Yem-alpha is a member of the Ubinuclein/HPC2 family of proteins that have recently been implicated in playing roles in chromatin remodeling in concert with HIRA histone chaperone. The yem1 mutant females exhibited disrupted chromosome behavior in the first meiotic division and produced very low numbers of viable progeny. Unexpectedly these progeny did not display paternal chromosome markers, suggesting that they developed from diploid gametes that underwent gynogenesis, a form of parthenogenesis that requires fertilization. Conclusions We focus here on the analysis of the meiotic defects exhibited by yem1 oocytes that could account for the formation of diploid gametes. Our results suggest that yem1 affects chromosome segregation presumably by affecting kinetochores function in the first meiotic division. This work paves the way to further investigations on the evolution of the mechanisms that support sexual reproduction. PMID:21080953

Change of Conditions of the Formation of the Karelian Province of the Baltic Shield Continental Crust during Transition from Meso- to Neoarchean: Geochemical Study Results

NASA Astrophysics Data System (ADS)

Chekulaev, V. P.; Arestova, N. A.; Egorova, Yu. S.; Kucherovskii, G. A.

2018-05-01

The compositions of the tonalite-trondhjemite-granodiorite (TTG) assemblage and volcanic rocks of the Archaean greenstone belts from different domains of the Karelian province of the Baltic Shield are compared. Neoarchean medium felsic volcanic rocks and TTG of the Central Karelian domain drastically differ from analogous Mesoarchean rocks of the neighboring Vodlozero and West Karelian domains in higher Rb, Sr, P, La, and Ce contents and, correspondingly, values of Sr/Y, La/Yb, and La/Sm, and also in a different REE content distribution owing to different rock sources of these domains. This fact is confirmed by differences in the composition and the nature of the REE distribution in the basic and ultrabasic volcanic rocks making up the greenstone belts of these domains. It is established that the average compositions of Mesoarchean TTG rocks and volcanic rocks of the Karelian province differ markedly from those of plagiogranitoids and volcanic rocks of the recent geotectonic environments in high Mg (mg#) and Sr contents. Neoarchean volcanic rocks of Karelia differ from recent island-arc volcanic rocks, but are similar in composition to recent volcanic rocks of the continental arcs. On the basis of the cumulative evidence, the Karelian province of the Baltic Shield was subject to dramatic changes in the crust formation conditions at the beginning of the Neoarchean at the turn of about 2.75-2.78 Ga. These changes led to formation of volcano-sedimentary and plutonic rock complexes, different in composition from Mesoarchean rocks, and specific complexes of intrusive sanukitoids and granites. Changes and variations in the rock composition were related to the mixing of plume sources with continental crust and/or lithospheric mantle material, likely as a result of the combined effect of plumes and plate tectonics. This process resulted in formation of a younger large fragment of the Archean crust such as the Central Karelian domain which factually connected more ancient

Recent experimental results of KSTAR RF heating and current drive

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, S. J., E-mail: sjwang@nfri.re.kr; Kim, J.; Jeong, J. H.

2015-12-10

The overview of KSTAR activities on ICRH, LHCD and ECH/CD including the last experimental results and future plan aiming for long-pulse high-beta plasma will be presented. Recently we achieved reasonable coupling of ICRF power to H-mode plasma through several efforts to increase system reliability. Power balance will be discussed on this experiment. LHCD is still struggling in the low power regime. Review of antenna spectrum for the higher coupling in H-mode plasma will be tried. ECH/CD provides 41 sec, 0.8 MW of heating power to support high-performance long-pulse discharge. Also, 170 GHz ECH system is integrated with the Plasma Control Systemmore » (PCS) for the feedback controlling of NTM. Status and plan of ECH/CD will be discussed. Finally, helicon current drive is being prepared for the next stage of KSTAR operation. The hardware preparation and the calculation results of helicon current drive in KSTAR plasma will be discussed.« less

Recent experimental results of KSTAR RF heating and current drive

NASA Astrophysics Data System (ADS)

Wang, S. J.; Kim, J.; Jeong, J. H.; Kim, H. J.; Joung, M.; Bae, Y. S.; Kwak, J. G.

2015-12-01

The overview of KSTAR activities on ICRH, LHCD and ECH/CD including the last experimental results and future plan aiming for long-pulse high-beta plasma will be presented. Recently we achieved reasonable coupling of ICRF power to H-mode plasma through several efforts to increase system reliability. Power balance will be discussed on this experiment. LHCD is still struggling in the low power regime. Review of antenna spectrum for the higher coupling in H-mode plasma will be tried. ECH/CD provides 41 sec, 0.8 MW of heating power to support high-performance long-pulse discharge. Also, 170 GHz ECH system is integrated with the Plasma Control System (PCS) for the feedback controlling of NTM. Status and plan of ECH/CD will be discussed. Finally, helicon current drive is being prepared for the next stage of KSTAR operation. The hardware preparation and the calculation results of helicon current drive in KSTAR plasma will be discussed.

Looking for the Phase Transition—Recent NA61/SHINE Results

NASA Astrophysics Data System (ADS)

Turko, Ludwik

2018-03-01

The fixed-target NA61/SHINE experiment (SPS CERN) looks for the critical point of strongly interacting matter and the properties of the onset of deconfinement. It is a two dimensional scan of measurements of particle spectra and fluctuations in proton-proton, proton-nucleus and nucleus-nucleus interactions as a function of collision energy and system size, corresponding to a two dimensional phase diagram (temperature T - baryonic chemical potential $\\mu_B$). New NA61/SHINE results are presented here, such as transverse momentum and multiplicity fluctuations in Ar+Sc collisions compared to NA61/SHINE p+p and Be+Be data, as well as to earlier NA49 A+A results. Recently, a preliminary signature for the new size dependent effect - rapid changes in system size dependence was observed in NA61-SHINE data, labeled as percolation threshold or onset of fireball. This would be closely related to the vicinity of the hadronic phase transition region.

Roles of Chondrocytes in Endochondral Bone Formation and Fracture Repair

PubMed Central

Hinton, R.J.; Jing, Y.; Jing, J.; Feng, J.Q.

2016-01-01

The formation of the mandibular condylar cartilage (MCC) and its subchondral bone is an important but understudied topic in dental research. The current concept regarding endochondral bone formation postulates that most hypertrophic chondrocytes undergo programmed cell death prior to bone formation. Under this paradigm, the MCC and its underlying bone are thought to result from 2 closely linked but separate processes: chondrogenesis and osteogenesis. However, recent investigations using cell lineage tracing techniques have demonstrated that many, perhaps the majority, of bone cells are derived via direct transformation from chondrocytes. In this review, the authors will briefly discuss the history of this idea and describe recent studies that clearly demonstrate that the direct transformation of chondrocytes into bone cells is common in both long bone and mandibular condyle development and during bone fracture repair. The authors will also provide new evidence of a distinct difference in ossification orientation in the condylar ramus (1 ossification center) versus long bone ossification formation (2 ossification centers). Based on our recent findings and those of other laboratories, we propose a new model that contrasts the mode of bone formation in much of the mandibular ramus (chondrocyte-derived) with intramembranous bone formation of the mandibular body (non-chondrocyte-derived). PMID:27664203

Preferences on technical report format - Results of a survey

NASA Technical Reports Server (NTRS)

Pinelli, T. E.; Cordle, V. M.; Glassman, M.; Vondran, R. F.

1984-01-01

A survey of 513 engineers and scientists employed at the National Aeronautics and Space Administration Langley Research Center and 600 engineers and scientists from three professional/technical societies solicited the opinions of report users concerning the format of NASA technical reports. The results indicate that a summary as well as an abstract should be included, that the definitions of symbols and glossary of terms should be located in the front of the report, and that the illustrative material should be integrated with the text rather than grouped at the end of the report. Citation of references by number, one-column, ragged-right-margin layout, and third-person writing style are also preferred by a majority of the respondents.

Ediacaran paleomagnetic results from feeder dikes of the Catoctin Formation

NASA Astrophysics Data System (ADS)

Hankard, F.; Domeier, M. M.; Bentley, C.; Van Der Voo, R.

2011-12-01

A paleomagnetic study undertaken sixteen years ago on the Catoctin basalts, feeder dikes and sills (Meert et al, 1994) did not bring firm and strong conclusions about the paleoposition of Laurentia during the Ediacaran period. The results were rather complex and sketchy. In effect, three paleomagnetic directions derived from this study were interpreted as follows: one placed Laurentia at high southerly latitude during Catoctin time while the other two were considered as later "remagnetization" events. One remagnetization was hypothesized to have been acquired in the Late Cambrian, when Laurentia was in an equatorial position, whereas a second one was attributed to Taconian mountain-building during the Ordovician period. In order to attempt to unravel the confusing late Precambrian paleogeography, we conducted a detailed paleomagnetic sampling in the Blue Ridge Province of Central Virginia. We focused on the dikes that fed the 568-555 Ma volcanism of the Catoctin Formation (Southworth et al, 2009) in the Shenandoah National Park, as well as in several locations outside the park, and along the south shore of the Potomac River (Maryland). These new data should help to define unambiguously which (if any) of the magnetization components is primary for the Catoctin Formation.

Results of recent NASA studies on automatic spin prevention for fighter aircraft

NASA Technical Reports Server (NTRS)

Chambers, J. R.; Nguyen, L. T.

1976-01-01

A broad based research program was developed to eliminate or minimize inadvertent spins for advanced military aircraft. Recent piloted simulator studies and airplane flight tests have demonstrated that the automatic control systems in use on current fighters can be tailored to provide a high degree of spin resistance for some configurations without restrictions to maneuverability. Such systems result in greatly increased tactical effectiveness, safety, and pilot confidence.

Physics of primordial star formation

NASA Astrophysics Data System (ADS)

Yoshida, Naoki

2012-09-01

The study of primordial star formation has a history of nearly sixty years. It is generally thought that primordial stars are one of the key elements in a broad range of topics in astronomy and cosmology, from Galactic chemical evolution to the formation of super-massive blackholes. We review recent progress in the theory of primordial star formation. The standard theory of cosmic structure formation posits that the present-day rich structure of the Universe developed through gravitational amplification of tiny matter density fluctuations left over from the Big Bang. It has become possible to study primordial star formation rigorously within the framework of the standard cosmological model. We first lay out the key physical processes in a primordial gas. Then, we introduce recent developments in computer simulations. Finally, we discuss prospects for future observations of the first generation of stars.

Parameters of thermochemical plumes responsible for the formation of batholiths: Results of experimental simulation

NASA Astrophysics Data System (ADS)

Kirdyashkin, A. A.; Kirdyashkin, A. G.; Gurov, V. V.

2017-07-01

Based on laboratory and theoretical modeling results, we present the thermal and hydrodynamical structure of the plume conduit during plume ascent and eruption on the Earth's surface. The modeling results show that a mushroom-shaped plume head forms after melt eruption on the surface for 1.9 < Ka < 10. Such plumes can be responsible for the formation of large intrusive bodies, including batholiths. The results of laboratory modeling of plumes with mushroom-shaped heads are presented for Ka = 8.7 for a constant viscosity and uniform melt composition. Images of flow patterns are obtained, as well as flow velocity profiles in the melt of the conduit and the head of the model plume. Based on the laboratory modeling data, we present a scheme of a thermochemical plume with a mushroom-shaped head responsible for the formation of a large intrusive body (batholith). After plume eruption to the surface, melting occurs along the base of the massif above the plume head, resulting in a mushroom-shaped plume head. A possible mechanism for the formation of localized surface manifestations of batholiths is presented. The parameters of some plumes with mushroom-shaped heads (plumes of the Altay-Sayan and Barguzin-Vitim large-igneous provinces, and Khangai and Khentei plumes) are estimated using geological data, including age intervals and volumes of magma melts.

Planck 2013 results. XXX. Cosmic infrared background measurements and implications for star formation

NASA Astrophysics Data System (ADS)

Planck Collaboration; Ade, P. A. R.; Aghanim, N.; Armitage-Caplan, C.; Arnaud, M.; Ashdown, M.; Atrio-Barandela, F.; Aumont, J.; Baccigalupi, C.; Banday, A. J.; Barreiro, R. B.; Bartlett, J. G.; Battaner, E.; Benabed, K.; Benoît, A.; Benoit-Lévy, A.; Bernard, J.-P.; Bersanelli, M.; Bethermin, M.; Bielewicz, P.; Blagrave, K.; Bobin, J.; Bock, J. J.; Bonaldi, A.; Bond, J. R.; Borrill, J.; Bouchet, F. R.; Boulanger, F.; Bridges, M.; Bucher, M.; Burigana, C.; Butler, R. C.; Cardoso, J.-F.; Catalano, A.; Challinor, A.; Chamballu, A.; Chen, X.; Chiang, H. C.; Chiang, L.-Y.; Christensen, P. R.; Church, S.; Clements, D. L.; Colombi, S.; Colombo, L. P. L.; Couchot, F.; Coulais, A.; Crill, B. P.; Curto, A.; Cuttaia, F.; Danese, L.; Davies, R. D.; Davis, R. J.; de Bernardis, P.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Delouis, J.-M.; Désert, F.-X.; Dickinson, C.; Diego, J. M.; Dole, H.; Donzelli, S.; Doré, O.; Douspis, M.; Dupac, X.; Efstathiou, G.; Enßlin, T. A.; Eriksen, H. K.; Finelli, F.; Forni, O.; Frailis, M.; Franceschi, E.; Galeotta, S.; Ganga, K.; Ghosh, T.; Giard, M.; Giraud-Héraud, Y.; González-Nuevo, J.; Górski, K. M.; Gratton, S.; Gregorio, A.; Gruppuso, A.; Hansen, F. K.; Hanson, D.; Harrison, D.; Helou, G.; Henrot-Versillé, S.; Hernández-Monteagudo, C.; Herranz, D.; Hildebrandt, S. R.; Hivon, E.; Hobson, M.; Holmes, W. A.; Hornstrup, A.; Hovest, W.; Huffenberger, K. M.; Jaffe, A. H.; Jaffe, T. R.; Jones, W. C.; Juvela, M.; Kalberla, P.; Keihänen, E.; Kerp, J.; Keskitalo, R.; Kisner, T. S.; Kneissl, R.; Knoche, J.; Knox, L.; Kunz, M.; Kurki-Suonio, H.; Lacasa, F.; Lagache, G.; Lähteenmäki, A.; Lamarre, J.-M.; Langer, M.; Lasenby, A.; Laureijs, R. J.; Lawrence, C. R.; Leonardi, R.; León-Tavares, J.; Lesgourgues, J.; Liguori, M.; Lilje, P. B.; Linden-Vørnle, M.; López-Caniego, M.; Lubin, P. M.; Macías-Pérez, J. F.; Maffei, B.; Maino, D.; Mandolesi, N.; Maris, M.; Marshall, D. J.; Martin, P. G.; Martínez-González, E.; Masi, S.; Massardi, M.; Matarrese, S.; Matthai, F.; Mazzotta, P.; Melchiorri, A.; Mendes, L.; Mennella, A.; Migliaccio, M.; Mitra, S.; Miville-Deschênes, M.-A.; Moneti, A.; Montier, L.; Morgante, G.; Mortlock, D.; Munshi, D.; Murphy, J. A.; Naselsky, P.; Nati, F.; Natoli, P.; Netterfield, C. B.; Nørgaard-Nielsen, H. U.; Noviello, F.; Novikov, D.; Novikov, I.; Osborne, S.; Oxborrow, C. A.; Paci, F.; Pagano, L.; Pajot, F.; Paladini, R.; Paoletti, D.; Partridge, B.; Pasian, F.; Patanchon, G.; Perdereau, O.; Perotto, L.; Perrotta, F.; Piacentini, F.; Piat, M.; Pierpaoli, E.; Pietrobon, D.; Plaszczynski, S.; Pointecouteau, E.; Polenta, G.; Ponthieu, N.; Popa, L.; Poutanen, T.; Pratt, G. W.; Prézeau, G.; Prunet, S.; Puget, J.-L.; Rachen, J. P.; Reach, W. T.; Rebolo, R.; Reinecke, M.; Remazeilles, M.; Renault, C.; Ricciardi, S.; Riller, T.; Ristorcelli, I.; Rocha, G.; Rosset, C.; Roudier, G.; Rowan-Robinson, M.; Rubiño-Martín, J. A.; Rusholme, B.; Sandri, M.; Santos, D.; Savini, G.; Scott, D.; Seiffert, M. D.; Serra, P.; Shellard, E. P. S.; Spencer, L. D.; Starck, J.-L.; Stolyarov, V.; Stompor, R.; Sudiwala, R.; Sunyaev, R.; Sureau, F.; Sutton, D.; Suur-Uski, A.-S.; Sygnet, J.-F.; Tauber, J. A.; Tavagnacco, D.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Tristram, M.; Tucci, M.; Tuovinen, J.; Türler, M.; Valenziano, L.; Valiviita, J.; Van Tent, B.; Vielva, P.; Villa, F.; Vittorio, N.; Wade, L. A.; Wandelt, B. D.; Welikala, N.; White, M.; White, S. D. M.; Winkel, B.; Yvon, D.; Zacchei, A.; Zonca, A.

2014-11-01

We present new measurements of cosmic infrared background (CIB) anisotropies using Planck. Combining HFI data with IRAS, the angular auto- and cross-frequency power spectrum is measured from 143 to 3000 GHz, and the auto-bispectrum from 217 to 545 GHz. The total areas used to compute the CIB power spectrum and bispectrum are about 2240 and 4400 deg2, respectively. After careful removal of the contaminants (cosmic microwave background anisotropies, Galactic dust, and Sunyaev-Zeldovich emission), and a complete study of systematics, the CIB power spectrum is measured with unprecedented signal to noise ratio from angular multipoles ℓ ~ 150 to 2500. The bispectrum due to the clustering of dusty, star-forming galaxies is measured from ℓ ~ 130 to 1100, with a total signal to noise ratio of around 6, 19, and 29 at 217, 353, and 545 GHz, respectively. Two approaches are developed for modelling CIB power spectrum anisotropies. The first approach takes advantage of the unique measurements by Planck at large angular scales, and models only the linear part of the power spectrum, with a mean bias of dark matter haloes hosting dusty galaxies at a given redshift weighted by their contribution to the emissivities. The second approach is based on a model that associates star-forming galaxies with dark matter haloes and their subhaloes, using a parametrized relation between the dust-processed infrared luminosity and (sub-)halo mass. The two approaches simultaneously fit all auto- and cross-power spectra very well. We find that the star formation history is well constrained up to redshifts around 2, and agrees with recent estimates of the obscured star-formation density using Spitzer and Herschel. However, at higher redshift, the accuracy of the star formation history measurement is strongly degraded by the uncertainty in the spectral energy distribution of CIB galaxies. We also find that the mean halo mass which is most efficient at hosting star formation is log (Meff/M⊙) = 12

The formation of galaxies

NASA Technical Reports Server (NTRS)

Efstathiou, G.; Silk, J.

1983-01-01

Current models of galaxy formation are examined in a review of recent observational and theoretical studies. Observational data on elliptical galaxies, disk galaxies, luminosity functions, clustering, and angular fluctuations in the cosmic microwave background are summarized. Theoretical aspects discussed include the origin and early evolution of small fluctuations, matter and radiation fluctuations, the formation of large-scale structure, dissipationless galaxy formation, galaxy mergers, dissipational galaxy formation, and the implications of particle physics (GUTs, massive neutrinos, and gravitinos) for cosmology.

High avidity anti-integrase antibodies discriminate recent and non-recent HIV infection: Implications for HIV incidence assay.

PubMed

Rikhtegaran Tehrani, Zahra; Azadmanesh, Kayhan; Mostafavi, Ehsan; Gharibzadeh, Safoora; Soori, Shahrzad; Azizi, Mohammad; Khabiri, Alireza

2018-03-01

Estimation of HIV incidence provides real-time information of HIV transmission trends for decision makers. Anti-integrase antibodies are the last ones produced during seroconversion and presence of high-avidity anti-integrase antibodies indicates the chronicity of HIV infection. This study aimed to evaluate the performance of these antibodies in discriminating of recent from non-recent HIV infection. For this purpose, different ELISA formats were developed to detect high-avidity anti-integrase antibodies in a commercially available performance panel, and the best assay was selected for further evaluation. The false recent rate of the selected assay was evaluated in a panel of Iranian patients and compared to two commercial assays, BED-EIA and LAg-Avidity. While the false recent rate of the developed assay was 3.8%, it was 14.1% and 1.3% for BED-EIA and LAg-Avidity, respectively. To our knowledge, this is the first report to study the performance of high-avidity anti-integrase antibodies for classification of HIV infection. The preliminary results showed that the specificity of the newly developed assay is markedly higher than BED-EIA and is comparable with LAg-Avidity. The promising results point to the potential use of anti-integrase antibodies as a biomarker in HIV incidence laboratory tests or algorithms. The developed assay needs further evaluation in future. Copyright © 2017 Elsevier B.V. All rights reserved.

Language and counting: Some recent results

NASA Astrophysics Data System (ADS)

Bell, Garry

1990-02-01

It has long been recognised that the language of mathematics is an important variable in the learning of mathematics, and there has been useful work in isolating and describing the linkage. Steffe and his co-workers at Georgia, for example, (Steffe, von Glasersfeld, Richardson and Cobb, 1983) have suggested that young children may construct verbal countable items to count objects which are hidden from their view. Although there has been a surge of research interest in counting and early childhood mathematics, and in cultural differences in mathematics attainment, there has been little work reported on the linkage between culture as exemplified by language, and initial concepts of numeration. This paper reports on some recent clinical research with kindergarten children of European and Asian background in Australia and America. The research examines the influence that number naming grammar appears to have on young children's understandings of two-digit numbers and place value. It appears that Transparent Standard Number Word Sequences such as Japanese, Chinese and Vietnamese which follow the numerical representation pattern by naming tens and units in order ("two tens three"), may be associated with distinctive place value concepts which may support sophisticated mental algorithms.

Star Formation Histories of the LEGUS Dwarf Galaxies. I. Recent History of NGC 1705, NGC 4449, and Holmberg II

NASA Astrophysics Data System (ADS)

Cignoni, M.; Sacchi, E.; Aloisi, A.; Tosi, M.; Calzetti, D.; Lee, J. C.; Sabbi, E.; Adamo, A.; Cook, D. O.; Dale, D. A.; Elmegreen, B. G.; Gallagher, J. S., III; Gouliermis, D. A.; Grasha, K.; Grebel, E. K.; Hunter, D. A.; Johnson, K. E.; Messa, M.; Smith, L. J.; Thilker, D. A.; Ubeda, L.; Whitmore, B. C.

2018-03-01

We use Hubble Space Telescope observations from the Legacy Extragalactic UV Survey to reconstruct the recent star formation histories (SFHs) of three actively star-forming dwarf galaxies, NGC 4449, Holmberg II, and NGC 1705, from their UV color–magnitude diagrams (CMDs). We apply a CMD fitting technique using two independent sets of stellar isochrones, PARSEC-COLIBRI and MIST, to assess the uncertainties related to stellar evolution modeling. Irrespective of the adopted stellar models, all three dwarfs are found to have had almost constant star formation rates (SFRs) in the last 100–200 Myr, with modest enhancements (a factor of ∼2) above the 100 Myr averaged SFR. Significant differences among the three dwarfs are found in terms of the overall SFR, the timing of the most recent peak, and the SFR/area. The initial mass function of NGC 1705 and Holmberg II is consistent with a Salpeter slope down to ≈5 M ⊙, whereas it is slightly flatter, s = ‑2.0, in NGC 4449. The SFHs derived with the two different sets of stellar models are consistent with each other, except for some quantitative details, attributable to their input assumptions. They also share the drawback that all synthetic diagrams predict a clear separation in color between the upper main-sequence and helium-burning stars, which is not apparent in the data. Since neither differential reddening, which is significant in NGC 4449, nor unresolved binaries appear to be sufficient to fill the gap, we suggest this calls for a revision of both sets of stellar evolutionary tracks. Based on observations obtained with the NASA/ESA Hubble Space Telescope at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy under NASA Contract NAS 5-26555.

Recent Results From The Nasa Earth Science Terra Mission and Future Possibilities

NASA Technical Reports Server (NTRS)

Salomonson, Vincent V.

2000-01-01

The NASA Earth Sciences Enterprise has made some remarkable strides in recent times in using developing, implementing, and utilizing spaceborne observations to better understand how the Earth works as a coupled, interactive system of the land, ocean, and atmosphere. Notable examples include the Upper Atmosphere Research (UARS) Satellite, the Topology Ocean Experiment (TOPEX) mission, Landsat-7, SeaWiFS, the Tropical Rainfall Monitoring Mission (TRMM), Quickscatt, the Shuttle Radar Topography Mission (SRTM), and, quite recently, the Terra'/Earth Observing System-1 mission. The Terra mission, for example, represents a major step forward in providing sensors that offer considerable advantages and progress over heritage instruments. The Moderate Resolution Imaging Spectrometer (MODIS), the Multi-angle Imaging SpectroRadiometer (MISR), the Measurements of Pollution in the Troposphere (MOPITT), the Advanced Spaceborne Thermal Emissions and Reflections (ASTER) radiometer, and the Clouds and Earth's Radiant Energy System (CERES) radiometer are the instruments involved. Early indications in March indicate that each of these instruments are working well and will be augmenting data bases from heritage instruments as well as producing new, unprecedented observations of land, ocean, and atmosphere features. Several missions will follow the Terra mission as the Earth Observing mission systems complete development and go into operation. These missions include EOS PM-1/'Aqua', Icesat, Vegetation Canopy Lidar (VCL), Jason/TOPEX Follow-on, the Chemistry mission, etc. As the Earth Observing systems completes its first phase in about 2004 a wealth of data enabling better understanding of the Earth and the management of its resources will have been provided. Considerable thought is beginning to be placed on what advances in technology can be implemented that will enable further advances in the early part of the 21st century; e.g., in the time from of 2020. Concepts such as

Catastrophic disruption experiments: Recent results

NASA Technical Reports Server (NTRS)

Martelli, G.; Ryan, E. V.; Nakamura, A. M.; Giblin, I.

1994-01-01

This paper presents a review of the progress in the field of catastrophic disruption experiments over the past 4 years, since the publication of the review paper by Fujiwara et al. (1989). We describe the development of new techniques to produce shattering impacts relevant to the study of the collisional evolution of the asteroids, and summarize the results from numerous experiments which have been performed to date, using a variety of materials for both the impactor and the targets. Some of these, such as ice-on-ice, loose aggregates and pressurized targets, are quite new and have provided novel and exciting results. Some of the gaps existing previously in the data on fragment ejection-angle distributions, as well as translational and rotational velocity fields (including fine fragments) have been filled, and these new results will be surveyed.

Documenting the conversion from traditional to Studio Physics formats at the Colorado School of Mines: Process and early results

NASA Astrophysics Data System (ADS)

Kohl, Patrick B.; Kuo, H. Vincent; Ruskell, Todd G.

2008-10-01

The Colorado School of Mines (CSM) has taught its first-semester introductory physics course using a hybrid lecture/Studio Physics format for several years. Over the past year we have converted the second semester of our calculus-based introductory physics course (Physics II) to a Studio Physics format, starting from a traditional lecture-based format. In this paper, we document the early stages of this conversion in order to better understand which features succeed and which do not, and in order to develop a model for switching to Studio that keeps the time and resource investment manageable. We describe the recent history of the Physics II course and of Studio at Mines, discuss the PER-based improvements that we are implementing, and characterize our progress via several metrics, including pre/post Conceptual Survey of Electricity and Magnetism (CSEM) scores, Colorado Learning About Science Survey scores (CLASS), solicited student comments, failure rates, and exam scores.

Recent Results from the WASA-at-COSY Experiment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kupsc, Andrzej

2011-10-24

Studies of light meson decays are the key experiments for the WASA detector at COSY-Juelich. One of the world largest data samples of the {eta} meson decays have been recently collected in the pd {yields}{sup 3}He{eta} and in the pp {yields} pp{eta} reactions. The status of the analysis of various decay channels and the further plans for the light meson decay program are presented.

Recent high energy gamma-ray results from SAS-2

NASA Technical Reports Server (NTRS)

Thompson, D. J.; Fichtel, C. E.; Hartman, R. C.; Kniffen, D. A.; Bignami, G. F.; Ogelman, H. B.; Ozel, M. E.; Tumer, T.; Lamb, R. C.

1977-01-01

Recent developments in gamma-ray astronomy due to the results from SAS-2 have focused on two areas. First, the emission from the plane of the Galaxy is the dominant feature in the gamma-ray sky. The galactic latitude and longitude distributions are consistent with the concept that the high-energy radiation originates from cosmic rays interacting with interstellar matter, and the measurements support a galactic origin for cosmic rays. Second, searches of the SAS-2 data for emission from localized sources have shown three strong discrete gamma-ray sources: the Crab nebula and PSR 0531 + 21, the Vela supernova remnant and PSR 0833-45, and a source near galactic coordinates 193 deg longitude, +3 deg latitude, which does not appear to be associated with other known celestial objects. Evidence has also been found for pulsed gamma-ray emission from two other radio pulsars, PSR 1818-04 and PSR 1747-46. A localized source near longitudes 76-80 deg may be associated with the X-ray source Cyg X-3.

Recent Results from Galileo PPR at Io: Orbits I31 and I32

NASA Technical Reports Server (NTRS)

Rathbun, J. A.; Spencer, J. R.; Tamppari, L. K.; Martin, T. Z.; Barnard, L.; Travis, L. D.

2002-01-01

Recent Galileo PPR (Photo-Polarimeter Radiometer) results will be shown, including global day and nighttime maps, high latitude regional maps, and high-resolution scans across hotspots and from pole to pole. SO2 vapor pressure, global heatflow, and hotspot power outputs are estimated. Additional information is contained in the original extended abstract.

A model for the origin of bursty star formation in galaxies

NASA Astrophysics Data System (ADS)

Faucher-Giguère, Claude-André

2018-01-01

We propose a simple analytic model to understand when star formation is time steady versus bursty in galaxies. Recent models explain the observed Kennicutt-Schmidt relation between star formation rate and gas surface densities in galaxies as resulting from a balance between stellar feedback and gravity. We argue that bursty star formation occurs when such an equilibrium cannot be stably sustained, and identify two regimes in which galaxy-scale star formation should be bursty: (i) at high redshift (z ≳ 1) for galaxies of all masses, and (ii) at low masses (depending on gas fraction) for galaxies at any redshift. At high redshift, characteristic galactic dynamical time-scales become too short for supernova feedback to effectively respond to gravitational collapse in galactic discs (an effect recently identified for galactic nuclei), whereas in dwarf galaxies star formation occurs in too few bright star-forming regions to effectively average out. Burstiness is also enhanced at high redshift owing to elevated gas fractions in the early Universe. Our model can thus explain the bursty star formation rates predicted in these regimes by recent high-resolution galaxy formation simulations, as well as the bursty star formation histories observationally inferred in both local dwarf and high-redshift galaxies. In our model, bursty star formation is associated with particularly strong spatiotemporal clustering of supernovae. Such clustering can promote the formation of galactic winds and our model may thus also explain the much higher wind mass loading factors inferred in high-redshift massive galaxies relative to their z ∼ 0 counterparts.

A single mutation results in diploid gamete formation and parthenogenesis in a Drosophila yemanuclein-alpha meiosis I defective mutant.

PubMed

Meyer, Régis E; Delaage, Michèle; Rosset, Roland; Capri, Michèle; Aït-Ahmed, Ounissa

2010-11-16

Sexual reproduction relies on two key events: formation of cells with a haploid genome (the gametes) and restoration of diploidy after fertilization. Therefore the underlying mechanisms must have been evolutionary linked and there is a need for evidence that could support such a model. We describe the identification and the characterization of yem1, the first yem-alpha mutant allele (V478E), which to some extent affects diploidy reduction and its restoration. Yem-alpha is a member of the Ubinuclein/HPC2 family of proteins that have recently been implicated in playing roles in chromatin remodeling in concert with HIRA histone chaperone. The yem1 mutant females exhibited disrupted chromosome behavior in the first meiotic division and produced very low numbers of viable progeny. Unexpectedly these progeny did not display paternal chromosome markers, suggesting that they developed from diploid gametes that underwent gynogenesis, a form of parthenogenesis that requires fertilization. We focus here on the analysis of the meiotic defects exhibited by yem1 oocytes that could account for the formation of diploid gametes. Our results suggest that yem1 affects chromosome segregation presumably by affecting kinetochores function in the first meiotic division. This work paves the way to further investigations on the evolution of the mechanisms that support sexual reproduction.

Planet Formation

NASA Astrophysics Data System (ADS)

Klahr, Hubert; Brandner, Wolfgang

2006-05-01

This volume addresses fundamental questions concerning the formation of planetary systems in general, and of our solar system in particular. Drawing from recent advances in observational, experimental, and theoretical research, it summarises our current understanding of the planet formation processes, and addresses major open questions and research issues. Chapters are written by leading experts in the field of planet formation and extrasolar planet studies. The book is based on a meeting held at Ringberg Castle in Bavaria, where experts gathered together to present and exchange their ideas and findings. It is a comprehensive resource for graduate students and researchers, and is written to be accessible to newcomers to the field.

Evolved Gas Analyses of the Murray Formation in Gale Crater, Mars: Results of the Curiosity Rover's Sample Analysis at Mars (SAM) Instrument

NASA Technical Reports Server (NTRS)

Sutter, B.; McAdam, A. C.; Rampe, E. B.; Thompson, L. M.; Ming, D. W.; Mahaffy, P. R.; Navarro-Gonzalez, R.; Stern, J. C.; Eigenbrode, J. L.; Archer, P. D.

2017-01-01

The Sample Analysis at Mars (SAM) instrument aboard the Mars Science Laboratory rover has analyzed 13 samples from Gale Crater. All SAM-evolved gas analyses have yielded a multitude of volatiles (e.g., H2O, SO2, H2S, CO2, CO, NO, O2, HCl) [1- 6]. The objectives of this work are to 1) Characterize recent evolved SO2, CO2, O2, and NO gas traces of the Murray formation mudstone, 2) Constrain sediment mineralogy/composition based on SAM evolved gas analysis (SAM-EGA), and 3) Discuss the implications of these results relative to understanding the geological history of Gale Crater.

The accelerating pace of star formation

NASA Astrophysics Data System (ADS)

Caldwell, Spencer; Chang, Philip

2018-03-01

We study the temporal and spatial distribution of star formation rates in four well-studied star-forming regions in local molecular clouds (MCs): Taurus, Perseus, ρ Ophiuchi, and Orion A. Using published mass and age estimates for young stellar objects in each system, we show that the rate of star formation over the last 10 Myr has been accelerating and is (roughly) consistent with a t2 power law. This is in line with previous studies of the star formation history of MCs and with recent theoretical studies. We further study the clustering of star formation in the Orion nebula cluster. We examine the distribution of young stellar objects as a function of their age by computing an effective half-light radius for these young stars subdivided into age bins. We show that the distribution of young stellar objects is broadly consistent with the star formation being entirely localized within the central region. We also find a slow radial expansion of the newly formed stars at a velocity of v = 0.17 km s-1, which is roughly the sound speed of the cold molecular gas. This strongly suggests the dense structures that form stars persist much longer than the local dynamical time. We argue that this structure is quasi-static in nature and is likely the result of the density profile approaching an attractor solution as suggested by recent analytic and numerical analysis.

Biofilm formation and control in a simulated spacecraft water system - Interim results

NASA Technical Reports Server (NTRS)

Schultz, John R.; Taylor, Robert D.; Flanagan, David T.; Gibbons, Randall E.; Brown, Harlan D.; Sauer, Richard L.

1989-01-01

The ability of iodine to control microbial contamination and biofilm formation in spacecraft water distribution systems is studied using two stainless steel water subsystems. One subsystem has an iodine level of 2.5 mg/L maintained by an iodinated ion-exchange resin. The other subsystem has no iodine added. Stainless steel coupons are removed from each system to monitor biofilm formation. Results from the first six months of operation indicate that 2.5 mg/L of iodine has limited the number of viable bacteria that can be recovered from the iodinated subsystem. Epifluorescence microscopy of the coupons taken from this subsystem, however, indicates some evidence of microbial colonization after 15 weeks of operation. Numerous bacteria have been continually removed from both the water samples and the coupons taken from the noniodinated subsystem after only 3 weeks of operation.

Oklahoma’s recent earthquakes and saltwater disposal

PubMed Central

Walsh, F. Rall; Zoback, Mark D.

2015-01-01

Over the past 5 years, parts of Oklahoma have experienced marked increases in the number of small- to moderate-sized earthquakes. In three study areas that encompass the vast majority of the recent seismicity, we show that the increases in seismicity follow 5- to 10-fold increases in the rates of saltwater disposal. Adjacent areas where there has been relatively little saltwater disposal have had comparatively few recent earthquakes. In the areas of seismic activity, the saltwater disposal principally comes from “produced” water, saline pore water that is coproduced with oil and then injected into deeper sedimentary formations. These formations appear to be in hydraulic communication with potentially active faults in crystalline basement, where nearly all the earthquakes are occurring. Although most of the recent earthquakes have posed little danger to the public, the possibility of triggering damaging earthquakes on potentially active basement faults cannot be discounted. PMID:26601200

The Joint Physics Analysis Center: Recent results

NASA Astrophysics Data System (ADS)

Fernández-Ramírez, César

2016-10-01

We review some of the recent achievements of the Joint Physics Analysis Center, a theoretical collaboration with ties to experimental collaborations, that aims to provide amplitudes suitable for the analysis of the current and forthcoming experimental data on hadron physics. Since its foundation in 2013, the group is focused on hadron spectroscopy in preparation for the forthcoming high statistics and high precision experimental data from BELLEII, BESIII, CLAS12, COMPASS, GlueX, LHCb and (hopefully) PANDA collaborations. So far, we have developed amplitudes for πN scattering, KN scattering, pion and J/ψ photoproduction, two kaon photoproduction and three-body decays of light mesons (η, ω, ϕ). The codes for the amplitudes are available to download from the group web page and can be straightforwardly incorporated to the analysis of the experimental data.

Recent results from the Mainz Microtron MAMI and an outlook for the future

NASA Astrophysics Data System (ADS)

Denig, Achim

2016-05-01

We present recent results from the Mainz Microtron MAMI, which is a high intensity electron accelerator with (polarized) beam energies up to 1.6 GeV. Currently, two major experiments are operated at MAMI. The A1 spectrometer setup is ideally suited for high-resolution electron scattering experiments, which recently led to highly competitive results on electromagnetic form factors and dark photon searches. The second experiment is the Crystal Ball/TAPS calorimeter setup (A2 collaboration), which is operated at the tagged photon beam line. At A2, the baryon spectrum in the low-energy region is investigated in photo-production experiments. A polarized target for longitudinal and transversal beam polarization in combination with the polarized beam does not only allow for experiments in this field, but also opens the avenue for investigations of the polarizabilities of the nucleons, for which new results are presented in this paper. In addition, the high rate of pseudoscalar mesons produced via photo-production allows for measurements of meson decays as motivated by precision tests of chiral perturbation theory or precision tests of the Standard Model. We also outline the physics opportunities at the accelerator MESA (Mainz Energy-Recovering Superconducting Accelerator), which is currently under construction in Mainz.

A summary of recent results from the GRAPES-3 experiment

NASA Astrophysics Data System (ADS)

Gupta, S. K.

2017-06-01

The GRAPES-3 experiment is a combination of a high density extensive air shower (EAS) array of nearly 400 plastic scintillator detectors, and a large 560 m2 area tracking muon telescope with an energy threshold Eμ >1 GeV. GRAPES-3 has been operating continuously in Ooty, India since 2000. By accurately correcting for the effects of atmospheric pressure and temperature, the muon telescope provides a high precision directional survey of the galactic cosmic ray (GCR) intensity. This telescope has been used to observe the acceleration of muons during thunderstorm events. The recent discovery of a transient weakening of the Earth's magnetic shield through the detection of a GCR burst was the highlight of the GRAPES-3 results. We have an ongoing major expansion activity to further enhance the capability of the GRAPES-3 muon telescope by doubling its area.

Results of research and commercial production of shale oil in Bazhenov formation on Ai-Pimskoe field

NASA Astrophysics Data System (ADS)

Sarancha, A. V.; Shuldikova, N. S.; Mayer, A. V.; Sumin, A. N.

2017-10-01

A large number of articles devoted to Bazhenov Formation appeared in Russian scientific and technical journals, aimed at specialists in of oil and gas fields development over the last 5 - 10 years. This is due to the fact that traditional hydrocarbon resources are gradually reducing, making oil companies pay attention to shale oil; the largest deposits in the Russian Federation are in Bazhenov Formation. The main purpose of this article is to highlight results obtained during the development of Bazhenov Formation on Ai-Pimskoe field in Western Siberia.

Recent Results from ArgoNeuT and Status of MicroBooNE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Szelc, Andrzej

2015-07-10

Liquid Argon Time Projection Chamber (LArTPC) detectors hold the key to answering the outstanding questions about the role of neutrinos in the Standard Model of Particle physics and beyond. Their fine granularity combined with calorimetric capabilities allows for precision measurements that answering these questions will require. Here, we discuss the recent results from the ArgoNeuT experiment as well as the status and prospects for MicroBooNE, both a part of the US-based LArTPC neutrino program.

Stacked Star Formation Rate Profiles of Bursty Galaxies Exhibit “Coherent” Star Formation

NASA Astrophysics Data System (ADS)

Orr, Matthew E.; Hayward, Christopher C.; Nelson, Erica J.; Hopkins, Philip F.; Faucher-Giguère, Claude-André; Kereš, Dušan; Chan, T. K.; Schmitz, Denise M.; Miller, Tim B.

2017-11-01

In a recent work based on 3200 stacked Hα maps of galaxies at z˜ 1, Nelson et al. find evidence for “coherent star formation”: the stacked star formation rate (SFR) profiles of galaxies above (below) the “star formation main sequence” (MS) are above (below) that of galaxies on the MS at all radii. One might interpret this result as inconsistent with highly bursty star formation and evidence that galaxies evolve smoothly along the MS rather than crossing it many times. We analyze six simulated galaxies at z˜ 1 from the Feedback in Realistic Environments (FIRE) project in a manner analogous to the observations to test whether the above interpretations are correct. The trends in stacked SFR profiles are qualitatively consistent with those observed. However, SFR profiles of individual galaxies are much more complex than the stacked profiles: the former can be flat or even peak at large radii because of the highly clustered nature of star formation in the simulations. Moreover, the SFR profiles of individual galaxies above (below) the MS are not systematically above (below) those of MS galaxies at all radii. We conclude that the time-averaged coherent star formation evident stacks of observed galaxies is consistent with highly bursty, clumpy star formation of individual galaxies and is not evidence that galaxies evolve smoothly along the MS.

Non-chondritic iron isotope ratios in planetary mantles as a result of core formation

NASA Astrophysics Data System (ADS)

Elardo, Stephen M.; Shahar, Anat

2017-02-01

Information about the materials and conditions involved in planetary formation and differentiation in the early Solar System is recorded in iron isotope ratios. Samples from Earth, the Moon, Mars and the asteroid Vesta reveal significant variations in iron isotope ratios, but the sources of these variations remain uncertain. Here we present experiments that demonstrate that under the conditions of planetary core formation expected for the Moon, Mars and Vesta, iron isotopes fractionate between metal and silicate due to the presence of nickel, and enrich the bodies' mantles in isotopically light iron. However, the effect of nickel diminishes at higher temperatures: under conditions expected for Earth's core formation, we infer little fractionation of iron isotopes. From our experimental results and existing conceptual models of magma ocean crystallization and mantle partial melting, we find that nickel-induced fractionation can explain iron isotope variability found in planetary samples without invoking nebular or accretionary processes. We suggest that near-chondritic iron isotope ratios of basalts from Mars and Vesta, as well as the most primitive lunar basalts, were achieved by melting of isotopically light mantles, whereas the heavy iron isotope ratios of terrestrial ocean floor basalts are the result of melting of near-chondritic Earth mantle.

An Assessment of Recent Results on Pseudo-Stationary Oblique-Shock-Wave Reflections.

DTIC Science & Technology

1982-11-01

DATE AIR FORCE OFFICE-OF SCIENTIFIC RESEARCH/NA November 1982 BOLLING A&B, DC 20332 13. NUMBER OF PAGES 1.MONITORING AGENCY NAME A AODRESS~if differennt...equilibrium gas analysis would not be required for shock Mach numbers MN9 in N2, M84 6 in 029 M <Sin air andMC3in CO.. Yetatheavailahle experimeAaldata in S...2’ CO and very recent results for air , which are based on the criterion (consistent with relaxation lengths) of angle 6. between the incident and

Recent results and new hardware developments for protein crystal growth in microactivity

NASA Technical Reports Server (NTRS)

Delucas, L. J.; Long, M. M.; Moore, K. M.; Smith, C.; Carson, M.; Narayana, S. V. L.; Carter, D.; Clark, A. D., Jr.; Nanni, R. G.; Ding, J.

1993-01-01

Protein crystal growth experiments have been performed on 16 space shuttle missions since April, 1985. The initial experiments utilized vapor diffusion crystallization techniques similar to those used in laboratories for earth-based experiments. More recent experiments have utilized temperature induced crystallization as an alternative method for growing high quality protein crystals in microgravity. Results from both vapor diffusion and temperature induced crystallization experiments indicate that proteins grown in microgravity may be larger, display more uniform morphologies, and yield diffraction data to significantly higher resolutions than the best crystals of these proteins grown on earth.

Optical Pattern Formation in Cold Atoms: Explaining the Red-Blue Asymmetry

NASA Astrophysics Data System (ADS)

Schmittberger, Bonnie; Gauthier, Daniel

2013-05-01

The study of pattern formation in atomic systems has provided new insight into fundamental many-body physics and low-light-level nonlinear optics. Pattern formation in cold atoms in particular is of great interest in condensed matter physics and quantum information science because atoms undergo self-organization at ultralow input powers. We recently reported the first observation of pattern formation in cold atoms but found that our results were not accurately described by any existing theoretical model of pattern formation. Previous models describing pattern formation in cold atoms predict that pattern formation should occur using both red and blue-detuned pump beams, favoring a lower threshold for blue detunings. This disagrees with our recent work, in which we only observed pattern formation with red-detuned pump beams. Previous models also assume a two-level atom, which cannot account for the cooling processes that arise when beams counterpropagate through a cold atomic vapor. We describe a new model for pattern formation that accounts for Sisyphus cooling in multi-level atoms, which gives rise to a new nonlinearity via spatial organization of the atoms. This spatial organization causes a sharp red-blue detuning asymmetry, which agrees well with our experimental observations. We gratefully acknowledge the financial support of the NSF through Grant #PHY-1206040.

Meta-Analytic Methodology and Inferences about the Efficacy of Formative Assessment

ERIC Educational Resources Information Center

Briggs, Derek C.; Ruiz-Primo, Maria Araceli; Furtak, Erin; Shepard, Lorrie; Yin, Yue

2012-01-01

In a recent article published in "EM:IP," Kingston and Nash report on the results of a meta-analysis on the efficacy of formative assessment. They conclude that the average effect of formative assessment on student achievement is about 0.20 SD units. This would seem to dispel the myth that effects between 0.40 and 0.70 can be attributed to…

Competition for water vapour results in suppression of ice formation in mixed-phase clouds

NASA Astrophysics Data System (ADS)

Simpson, Emma L.; Connolly, Paul J.; McFiggans, Gordon

2018-05-01

The formation of ice in clouds can initiate precipitation and influence a cloud's reflectivity and lifetime, affecting climate to a highly uncertain degree. Nucleation of ice at elevated temperatures requires an ice nucleating particle (INP), which results in so-called heterogeneous freezing. Previously reported measurements for the ability of a particle to nucleate ice have been made in the absence of other aerosol which will act as cloud condensation nuclei (CCN) and are ubiquitous in the atmosphere. Here we show that CCN can outcompete INPs for available water vapour thus suppressing ice formation, which has the potential to significantly affect the Earth's radiation budget. The magnitude of this suppression is shown to be dependent on the mass of condensed water required for freezing. Here we show that ice formation in a state-of-the-art cloud parcel model is strongly dependent on the criteria for heterogeneous freezing selected from those previously hypothesised. We have developed an alternative criteria which agrees well with observations from cloud chamber experiments. This study demonstrates the dominant role that competition for water vapour can play in ice formation, highlighting both a need for clarity in the requirements for heterogeneous freezing and for measurements under atmospherically appropriate conditions.

Formative Constructs Implemented via Common Factors

ERIC Educational Resources Information Center

Treiblmaier, Horst; Bentler, Peter M.; Mair, Patrick

2011-01-01

Recently there has been a renewed interest in formative measurement and its role in properly specified models. Formative measurement models are difficult to identify, and hence to estimate and test. Existing solutions to the identification problem are shown to not adequately represent the formative constructs of interest. We propose a new two-step…

Neutron detection with noble gas scintillation: a review of recent results

NASA Astrophysics Data System (ADS)

Lavelle, C. M.; Coplan, Michael; Miller, Eric C.; Thompson, Alan K.; Kowler, Alex; Vest, Rob; Yue, Andrew; Koeth, Tim; Al-Sheikhly, Mohammad; Clark, Charles

2015-08-01

Thermal neutron detection is of vital importance to many disciplines, including neutron scattering, workplace monitoring, and homeland protection. We survey recent results from our collaboration which couple low-pressure noble gas scintillation with novel approaches to neutron absorbing materials and geometries to achieve potentially advantageous detector concepts. Noble gas scintillators were used for neutron detection as early as the late 1950's. Modern use of noble gas scintillation includes liquid and solid forms of argon and xenon in the dark matter and neutron physics experiments and commercially available high pressure applications have achieved high resolution gamma ray spectroscopy. Little attention has been paid to the overlap between low pressure noble gas scintillation and thermal neutron detection, for which there are many potential benefits.

Preferences of Knowledge Users for Two Formats of Summarizing Results from Systematic Reviews: Infographics and Critical Appraisals

PubMed Central

Crick, Katelynn; Hartling, Lisa

2015-01-01

Objectives To examine and compare preferences of knowledge users for two different formats of summarizing results from systematic reviews: infographics and critical appraisals. Design Cross-sectional. Setting Annual members’ meeting of a Network of Centres of Excellence in Knowledge Mobilization called TREKK (Translating Emergency Knowledge for Kids). TREKK is a national network of researchers, clinicians, health consumers, and relevant organizations with the goal of mobilizing knowledge to improve emergency care for children. Participants Members of the TREKK Network attending the annual meeting in October 2013. Outcome Measures Overall preference for infographic vs. critical appraisal format. Members’ rating of each format on a 10-point Likert scale for clarity, comprehensibility, and aesthetic appeal. Members’ impressions of the appropriateness of the two formats for their professional role and for other audiences. Results Among 64 attendees, 58 members provided feedback (91%). Overall, their preferred format was divided with 24/47 (51%) preferring the infographic to the critical appraisal. Preference varied by professional role, with 15/22 (68%) of physicians preferring the critical appraisal and 8/12 (67%) of nurses preferring the infographic. The critical appraisal was rated higher for clarity (mean 7.8 vs. 7.0; p = 0.03), while the infographic was rated higher for aesthetic appeal (mean 7.2 vs. 5.0; p<0.001). There was no difference between formats for comprehensibility (mean 7.6 critical appraisal vs. 7.1 infographic; p = 0.09). Respondents indicated the infographic would be most useful for patients and their caregivers, while the critical appraisal would be most useful for their professional roles. Conclusions Infographics are considered more aesthetically appealing for summarizing evidence; however, critical appraisal formats are considered clearer and more comprehensible. Our findings show differences in terms of audience-specific preferences for

Recent results from the University of Washington's 38 mm ram accelerator

NASA Technical Reports Server (NTRS)

De Turenne, J. A.; Chew, G.; Bruckner, A. P.

1992-01-01

The ram accelerator is a propulsive device that accelerates projectiles using gasdynamic cycles similar to those which generate thrust in airbreathing ramjets. The projectile, analogous to the centerbody of a ramjet, travels supersonically through a stationary tube containing a gaseous fuel and oxidizer mixture. The projectile itself carries no onboard propellant. A combustion zone follows the projectile and stabilizes the shock structure. The resulting pressure distribution continuously accelerates the projectile. Several modes of ram accelerator operation have been investigated experimentally and theoretically. At velocities below the Chapman-Jouguet (C-J) detonation speed of the propellant mixture, the thermally choked propulsion mode accelerates the projectiles. At projectile velocities between approximately 90 and 110 percent of the C-J speed, a transdetonative propulsion mode occurs. At velocities beyond 110 percent of the C-J speed, projectiles experience superdetonative propulsion. This paper presents recent experimental results from these propulsion modes obtained with the University of Washington's 38-mm bore ram accelerator. Data from investigations with hydrogen diluted-gas mixtures are also introduced.

Recent Doppler Backscattering results from EAST tokamak

NASA Astrophysics Data System (ADS)

Zhou, Chu; Liu, Adi; Zhang, Xiaohui; Hu, Jianqiang; Wang, Mingyuan; Yu, Changxuan; Liu, Wandong; Li, Hong; Lan, Tao; Sun, Xuan; Xie, Jinlin; Ding, Weixing; CAS Key Laboratory of Geospace Environment, University of Science and Technology of China Team; Department of Physics and Astronomy, University of California at Los Angeles Collaboration

2013-10-01

A Doppler reflectometer system has recently been installed in the EAST tokamak. It includes two separated systems, one for Q-band and the other for V-band. The optical system consists of a fixed flat mirror and a steerable parabolic mirror, which enabling the measurement of perpendicular wave number in the range of 4-22/cm, with the wave number resolution around 2/cm, while the radial location can cover the whole minor radius for L mode and the whole pedestal for H mode on EAST. A 2D Gaussion Ray tracing code is used to calculate the scattering location, the perpendicular wave number and the resolution. In EAST last experimental campaign the Doppler shifted signals have been obtained and the radial profiles of the perpendicular propagation velocity during L-mode and H-mode are calculated. The Er evolution during L-H and H-L transition have also been measured. The two separated systems are also used as a poloidal coherent system together to study the GAM in EAST tokamak.

On the impact of anthropogenic emissions on biogenic SOA formation above West Africa: results from DACCIWA aircraft field campaign

NASA Astrophysics Data System (ADS)

Brito, Joel; Freney, Evelyn; Colomb, Aurelie; Dupuy, Régis; Duplissy, Jonathan; Denjean, Cyrielle; Dominutti, Pamela; Batenburg, Anneke; Haslett, Sophie; Schulz, Christiane; Bourrianne, Thierry; Burnet, Frederic; Borbon, Agnès; Schneider, Johannes; Borrmann, Stephan; Coe, Hugh; Sellegri, Karine; Flamant, Cyrille; Knippertz, Peter; Schwarzenboeck, Alfons

2017-04-01

As part of the Dynamics-Aerosol-Chemistry-Cloud Interactions in West Africa (DACCIWA) project, airborne campaigns were designed to measure a large range of atmospheric constituents focusing on the improvement of our current understanding on the effect of anthropogenic emissions on regional climate. The targeted region, Southern West Africa, holds currently a population of over 340 million people, and is predicted by the United Nations to reach about 800 million by 2050. The climate in the region is characterized by a large-scale atmospheric circulation system which controls precipitation over a land area of about 6 million km2, directly impacting the water resources, agriculture and power generation of hundreds of millions of people. Besides its large natural variability, the West African monsoon system is also expected to be significantly affected by global and regional climate change, with large uncertainties on the role of local pollution. An important aspect assessing the impact of human activities on the local climate is thereby the understanding of aerosol sources and properties. The presented study details results of the DACCIWA measurement campaign using the French ATR42 research aircraft, which in combination with the German Falcon 20 and British Twin Otter aircraft, aimed to characterize physico-chemical properties of aerosols in the region using a suite of aerosol measurement techniques (e.g. C-TOF AMS, APITOF, SMPS, etc.) and supporting information from simultaneous trace gas measurements (e.g. PTRMS). This large dataset has been used to assess how anthropogenic emission (NOx, SO2, SO4) is impacting formation of biogenic secondary organic aerosol formation, in particular through the formation of isoprene epoxydiols (IEPOX). The recently collected data will certainly help understanding the coupling between human activities and regional climate in a sensitive, highly populated area.

Recent Results and the Future of the NA61/SHINE Strong Interactions Program

NASA Astrophysics Data System (ADS)

Łysakowski, B.

NA61/SHINE is a fixed target experiment at the CERN Super-Proton- Synchrotron. The main goals of the experiment are to discover the critical point of strongly interacting matter and study the properties of the onset of deconfnement. In order to reach these goals the collaboration studies hadron production properties in nucleus-nucleus, proton-proton and proton-nucleus interactions. In this talk, recent results on particle production in p+p interactions, as well as Be+Be and Ar+Sc collisions in the SPS energy range are reviewed. The results are compared with available world data. The future of the NA61/SHINE scientifc program is also presented.

Furan formation from fatty acids as a result of storage, gamma irradiation, UV-C and heat treatments.

PubMed

Fan, Xuetong

2015-05-15

The effects of gamma and UV-C irradiation in comparison with thermal processing and storage at 25°C on formation of furan from different fatty acids were investigated. Results showed that furan was generated from polyunsaturated fatty acids such as linoleic and linolenic acid during thermal (120°C, 25 min) and UV-C (11.5 J/cm(2)) treatments. Gamma irradiation (up to 20 kGy) did not induce formation of significant amounts of furan from any of the fatty acids studied. Storage of unsaturated fatty acid emulsions at 25°C for 3 days led to the formation of furan (7-11 ng/mL) even without prior thermal or non-thermal treatments. pH significantly impacted furan formation with >3.5 times more furan formed at pH 9 than at pHs 3 or 6 during 3 days at 25°C. The addition of Trolox, BHA, and propyl gallate had no significant effect on furan formation from linolenic acid while α-tocopherol and FeSO4 promoted furan formation. Published by Elsevier Ltd.

Natural abiotic formation of oxalic acid in soils: results from aromatic model compounds and soil samples.

PubMed

Studenroth, Sabine; Huber, Stefan G; Kotte, Karsten; Schöler, Heinz F

2013-02-05

Oxalic acid is the smallest dicarboxylic acid and plays an important role in soil processes (e.g., mineral weathering and metal detoxification in plants). We have first proven its abiotic formation in soils and investigated natural abiotic degradation processes based on the oxidation of soil organic matter, enhanced by Fe(3+) and H(2)O(2) as hydroxyl radical suppliers. Experiments with the model compound catechol and further hydroxylated benzenes were performed to examine a common degradation pathway and to presume a general formation mechanism of oxalic acid. Two soil samples were tested for the release of oxalic acid and the potential effects of various soil parameters on oxalic acid formation. Additionally, the soil samples were treated with different soil sterilization methods to prove the oxalic acid formation under abiotic soil conditions. Different series of model experiments were conducted to determine a range of factors including Fe(3+), H(2)O(2), reaction time, pH, and chloride concentration on oxalic acid formation. Under certain conditions, catechol is degraded up to 65.6% to oxalic acid referring to carbon. In serial experiments with two soil samples, oxalic acid was produced, and the obtained results are suggestive of an abiotic degradation process. In conclusion, Fenton-like conditions with low Fe(3+) concentrations and an excess of H(2)O(2) as well as acidic conditions were required for an optimal oxalic acid formation. The presence of chloride reduced oxalic acid formation.

Formation of soap bubbles by gas jet

NASA Astrophysics Data System (ADS)

Zhou, Maolei; Li, Min; Chen, Zhiyuan; Han, Jifeng; Liu, Dong

2017-12-01

Soap bubbles can be easily generated by various methods, while their formation process is complicated and still worth studying. A model about the bubble formation process was proposed in the study by Salkin et al. [Phys. Rev. Lett. 116, 077801 (2016)] recently, and it was reported that the bubbles were formed when the gas blowing velocity was above one threshold. However, after a detailed study of these experiments, we found that the bubbles could be generated in two velocity ranges which corresponded to the laminar and turbulent gas jet, respectively, and the predicted threshold was only effective for turbulent gas flow. The study revealed that the bubble formation was greatly influenced by the aerodynamics of the gas jet blowing to the film, and these results will help to further understand the formation mechanism of the soap bubble as well as the interaction between the gas jet and the thin liquid film.

Right-sided infective endocarditis: recent epidemiologic changes

PubMed Central

Yuan, Shi-Min

2014-01-01

Background: Infective endocarditis (IE) has been increasingly reported, however, little is available regarding recent development of right-sided IE. Methods: Right-sided IE was comprehensively analyzed based on recent 5⅓-year literature. Results: Portal of entry, implanted foreign material, and repaired congenital heart defects were the main predisposing risk factors. Vegetation size on the right-sided valves was much smaller than those beyond the valves. Multiple logistic regression analysis revealed that predisposing risk factors, and vegetation size and locations were independent predictive risks of patients’ survival. Conclusions: Changes of right-sided IE in the past 5⅓ years included younger patient age, and increased vegetation size, but still prominent Staphylococcus aureus infections. Complication spectrum has changed into more valve insufficiency, more embolic events, reduced abscess formation, and considerably decreased valve perforations. With effective antibiotic regimens, prognoses of the patients seemed to be better than before. PMID:24482708

Recent results from Daya Bay

NASA Astrophysics Data System (ADS)

Chua, Ming-chung

2016-11-01

Utilizing powerful nuclear reactors as antineutrino sources, high mountains to provide ample shielding from cosmic rays in the vicinity, and functionally identical detectors with large target volume for near-far relative measurement, the Daya Bay Reactor Neutrino Experiment has achieved unprecedented precision in measuring the neutrino mixing angle θ13 and the neutrino mass squared difference |Δm2ee|. I will report the latest Daya Bay results on neutrino oscillations and light sterile neutrino search.

Numerical simulation of the formation of a spiral galaxy

NASA Astrophysics Data System (ADS)

Williams, P. R.; Nelson, A. H.

2001-08-01

A simulation is described in which the numerical galaxy formed compares favourably in every measurable respect with contemporary bright spiral galaxies, including the formation of a distinct stellar bulge and large scale spiral arm shocks in the gas component. This is achieved in spite of the fact that only idealized proto-galactic initial conditions were used, and only simple phenomenological prescriptions for the physics of the interstellar medium (ISM) and star formation were implemented. In light of the emphasis in recent literature on the importance of the link between galaxy formation and models of the universe on cosmological scales, on the details of the physics of the ISM and star formation, and on apparent problems therein, the implications of this result are discussed.

Star formation in evolving molecular clouds

NASA Astrophysics Data System (ADS)

Völschow, M.; Banerjee, R.; Körtgen, B.

2017-09-01

Molecular clouds are the principle stellar nurseries of our universe; they thus remain a focus of both observational and theoretical studies. From observations, some of the key properties of molecular clouds are well known but many questions regarding their evolution and star formation activity remain open. While numerical simulations feature a large number and complexity of involved physical processes, this plethora of effects may hide the fundamentals that determine the evolution of molecular clouds and enable the formation of stars. Purely analytical models, on the other hand, tend to suffer from rough approximations or a lack of completeness, limiting their predictive power. In this paper, we present a model that incorporates central concepts of astrophysics as well as reliable results from recent simulations of molecular clouds and their evolutionary paths. Based on that, we construct a self-consistent semi-analytical framework that describes the formation, evolution, and star formation activity of molecular clouds, including a number of feedback effects to account for the complex processes inside those objects. The final equation system is solved numerically but at much lower computational expense than, for example, hydrodynamical descriptions of comparable systems. The model presented in this paper agrees well with a broad range of observational results, showing that molecular cloud evolution can be understood as an interplay between accretion, global collapse, star formation, and stellar feedback.

Star formation inside a galactic outflow.

PubMed

Maiolino, R; Russell, H R; Fabian, A C; Carniani, S; Gallagher, R; Cazzoli, S; Arribas, S; Belfiore, F; Bellocchi, E; Colina, L; Cresci, G; Ishibashi, W; Marconi, A; Mannucci, F; Oliva, E; Sturm, E

2017-04-13

Recent observations have revealed massive galactic molecular outflows that may have the physical conditions (high gas densities) required to form stars. Indeed, several recent models predict that such massive outflows may ignite star formation within the outflow itself. This star-formation mode, in which stars form with high radial velocities, could contribute to the morphological evolution of galaxies, to the evolution in size and velocity dispersion of the spheroidal component of galaxies, and would contribute to the population of high-velocity stars, which could even escape the galaxy. Such star formation could provide in situ chemical enrichment of the circumgalactic and intergalactic medium (through supernova explosions of young stars on large orbits), and some models also predict it to contribute substantially to the star-formation rate observed in distant galaxies. Although there exists observational evidence for star formation triggered by outflows or jets into their host galaxy, as a consequence of gas compression, evidence for star formation occurring within galactic outflows is still missing. Here we report spectroscopic observations that unambiguously reveal star formation occurring in a galactic outflow at a redshift of 0.0448. The inferred star-formation rate in the outflow is larger than 15 solar masses per year. Star formation may also be occurring in other galactic outflows, but may have been missed by previous observations owing to the lack of adequate diagnostics.

Preferences of Knowledge Users for Two Formats of Summarizing Results from Systematic Reviews: Infographics and Critical Appraisals.

PubMed

Crick, Katelynn; Hartling, Lisa

2015-01-01

To examine and compare preferences of knowledge users for two different formats of summarizing results from systematic reviews: infographics and critical appraisals. Cross-sectional. Annual members' meeting of a Network of Centres of Excellence in Knowledge Mobilization called TREKK (Translating Emergency Knowledge for Kids). TREKK is a national network of researchers, clinicians, health consumers, and relevant organizations with the goal of mobilizing knowledge to improve emergency care for children. Members of the TREKK Network attending the annual meeting in October 2013. Overall preference for infographic vs. critical appraisal format. Members' rating of each format on a 10-point Likert scale for clarity, comprehensibility, and aesthetic appeal. Members' impressions of the appropriateness of the two formats for their professional role and for other audiences. Among 64 attendees, 58 members provided feedback (91%). Overall, their preferred format was divided with 24/47 (51%) preferring the infographic to the critical appraisal. Preference varied by professional role, with 15/22 (68%) of physicians preferring the critical appraisal and 8/12 (67%) of nurses preferring the infographic. The critical appraisal was rated higher for clarity (mean 7.8 vs. 7.0; p = 0.03), while the infographic was rated higher for aesthetic appeal (mean 7.2 vs. 5.0; p<0.001). There was no difference between formats for comprehensibility (mean 7.6 critical appraisal vs. 7.1 infographic; p = 0.09). Respondents indicated the infographic would be most useful for patients and their caregivers, while the critical appraisal would be most useful for their professional roles. Infographics are considered more aesthetically appealing for summarizing evidence; however, critical appraisal formats are considered clearer and more comprehensible. Our findings show differences in terms of audience-specific preferences for presentation of research results. This study supports other research indicating

Recent Advances in Biointegrated Optoelectronic Devices.

PubMed

Xu, Huihua; Yin, Lan; Liu, Chuan; Sheng, Xing; Zhao, Ni

2018-05-28

With recent progress in the design of materials and mechanics, opportunities have arisen to improve optoelectronic devices, circuits, and systems in curved, flexible, stretchable, and biocompatible formats, thereby enabling integration of customized optoelectronic devices and biological systems. Here, the core material technologies of biointegrated optoelectronic platforms are discussed. An overview of the design and fabrication methods to form semiconductor materials and devices in flexible and stretchable formats is presented, strategies incorporating various heterogeneous substrates, interfaces, and encapsulants are discussed, and their applications in biomimetic, wearable, and implantable systems are highlighted. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Recent Results From MINERvA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Patrick, Cheryl

The MINERvA detector is situated in Fermilab's NuMI beam, which provides neutrinos and antineutrinos in the 1-20 GeV range. It is designed to make precision cross-section measurements for scattering processes on various nuclei. These proceedings summarize the differential cross-section distributions measured for several different processes. Comparison of these with various models hints at additional nuclear effects not included in common simulations. These results will help constrain generators' nuclear models and reduce systematic uncertainties on their predictions. An accurate cross-section model, with minimal uncertainties, is vital to oscillation experiments.

Recent results on the cluster structure of light nuclei

NASA Astrophysics Data System (ADS)

Iachello, F.

2017-06-01

A recently developed model (ACM) is introduced and applied to the study of kα structures with k=2 (8Be ), k=3 (12C) and k=4 (16O). Evidence for Z2 (k=2), D3 (k=3) and Td (k=4) symmetry is presented. An extension (ACFM) of the model to kα+x(neutrons, protons) structures is briefly mentioned and applied to the study of9Be (k=2,x=1).

Laboratory analyses of micron-sized solid grains: Experimental techniques and recent results

NASA Technical Reports Server (NTRS)

Colangeli, L.; Bussoletti, E.; Blanco, A.; Borghesi, A.; Fonti, S.; Orofino, V.; Schwehm, G.

1989-01-01

Morphological and spectrophotometric investigations have been extensively applied in the past years to various kinds of micron and/or submicron-sized grains formed by materials which are candidate to be present in space. The samples are produced in the laboratory and then characterized in their physio-chemical properties. Some of the most recent results obtained on various kinds of carbonaceous materials are reported. Main attention is devoted to spectroscopic results in the VUV and IR wavelength ranges, where many of the analyzed samples show typical fingerprints which can be identified also in astrophysical and cometary materials. The laboratory methodologies used so far are also critically discussed in order to point out capabilities and present limitations, in the view of possible application to returned comet samples. Suggestions are given to develop new techniques which should overcome some of the problems faced in the manipulation and analysis of micron solid samples.

Observations of Young Stellar Objects with Infrared Interferometry: Recent Results from PTI, KI and IOTA

NASA Astrophysics Data System (ADS)

Akeson, Rachel

Young stellar objects have been one of the favorite targets of infrared interferometers for many years. In this contribution I will briefly review some of the first results and their contributions to the field and then describe some of the recent results from the Keck Interferometer (KI), the Palomar Testbed Interferometer (PTI) and the Infrared-Optical Telescope Array (IOTA). This conference also saw many exciting new results from the VLTI at both near and mid-infrared wavelengths that are covered by other contributions.

Very high energy observations of the Galactic Centre: recent results and perspectives with CTA

NASA Astrophysics Data System (ADS)

Terrier, Regis

2016-07-01

The central 300 pc of our Galaxy are a major laboratory for high energy astrophysics. They harbor the closest supermassive black hole (SMBH) and are the site of a sustained star formation activity. The energy released by the supernovae on the ambient medium must be very strong. Similarly, albeit extremely faint nowadays, the SMBH must have experienced episodes of intense activity in the past which can influence significantly the central regions and beyond, e.g. powering the Fermi bubbles. I review observational results at very high energies from the central region and discuss their implications and the questions they leave open. I discuss the perspectives CTA offers for Galactic Centre astrophysics.

Complex organic molecules and star formation

NASA Astrophysics Data System (ADS)

Bacmann, A.; Faure, A.

2014-12-01

Star forming regions are characterised by the presence of a wealth of chemical species. For the past two to three decades, ever more complex organic species have been detected in the hot cores of protostars. The evolution of these molecules in the course of the star forming process is still uncertain, but it is likely that they are partially incorporated into protoplanetary disks and then into planetesimals and the small bodies of planetary systems. The complex organic molecules seen in star forming regions are particularly interesting since they probably make up building blocks for prebiotic chemistry. Recently we showed that these species were also present in the cold gas in prestellar cores, which represent the very first stages of star formation. These detections question the models which were until now accepted to account for the presence of complex organic molecules in star forming regions. In this article, we shortly review our current understanding of complex organic molecule formation in the early stages of star formation, in hot and cold cores alike and present new results on the formation of their likely precursor radicals.

A Review of Secondary Organic Aerosol (SOA) Formation from Isoprene

EPA Science Inventory

Recent field and laboratory evidence indicates that the oxidation of isoprene forms secondary organic aerosol (SOA). Global biogenic emissions of isoprene (600 Tg yr^-1) are sufficiently large the formation of SOA is even small yields results in substantial production ...

N-terminal truncations in the FhlA protein result in formate- and MoeA-independent expression of the hyc (formate hydrogenlyase) operon of Escherichia coli.

PubMed

Self, W T; Hasona, A; Shanmugam, K T

2001-11-01

FhlA167 responded to formate. Removal of the first 117 amino acids of the FhlA protein appears to result in a constitutive, effector-independent activation of transcription of the genes encoding the components of the formate hydrogenlyase complex. The sequence similarity to ABC-ATPases, combined with the properties of the FhlA deletion proteins, led to the proposal that the N-terminal region of the native FhlA protein interacts with formate transport proteins, both as a formate transport facilitator and as a cytoplasmic acceptor.

Mesoarchean black shale -iron sedimentary sequences in Cleaverville Formation, Pilbara Australia: drilling preliminary result of DXCL2

NASA Astrophysics Data System (ADS)

Kiyokawa, S.; Ito, T.; Ikehara, M.; Yamaguchi, K. E.; Onoue, T.; Horie, K.; Sakamoto, R.; Teraji, S.; Aihara, Y.

2012-12-01

The 3.2-3.1 Ga Dixon island-Cleaverville formations are well-preserved hydrothermal oceanic sequence at oceanic island arc setting (Kiyokawa et al., 2002, 2006, 2012). The Dixon Island (3195+15 Ma) - Cleaverville (3108+13 Ma) formations formed volcano-sedimentary sequences with hydrothermal chert, black shale and banded iron formation to the top. Based on the scientific drilling as DXCL1 at 2007 and DXCL2 at 2011, lithology was clearly understood. Four drilling holes had been done at coastal sites; the Dixon Island Formation is DX site (100m) and the Cleaverville Formation is CL2 (40m), CL1 (60m) and CL3 (200m) sites and from stratigraphic bottom to top. These sequences formed coarsening and thickening upward black shale-BIF sequences. The Dixon Island Formation consists komatiite-rhyolite sequences with many hydrothermal veins and very fine laminated cherty rocks above them. The Cleaverville Formation contains black shale, fragments-bearing pyroclastic beds, white chert, greenish shale and BIF. Especially, CL3 core, which drilled through the Iron formation, shows siderite-chert beds above black shale identified before magnetite lamination bed. The magnetite bed formed very thin laminated bed with siderite lamination. This magnetite bed was covered by black shale beds again. New U-Pb SHRIMP data of the pyroclastic in black shale is 3109Ma. Estimated 2-8 cm/1000year sedimentation rate are identified in these sequences. Our preliminary result show that siderite and chert layers formed before magnetite iron sedimentation. The lower-upper sequence of organic carbon rich black shales are similar amount of organic content and 13C isotope (around -30per mill). So we investigate that the Archean iron formation, especially Cleaverville iron formation, was highly related by hydrothermal input and started pre-syn iron sedimentation at anoxic oceanic condition.

Identifying Risk Factors for Recent HIV Infection in Kenya Using a Recent Infection Testing Algorithm: Results from a Nationally Representative Population-Based Survey

PubMed Central

Kim, Andrea A.; Parekh, Bharat S.; Umuro, Mamo; Galgalo, Tura; Bunnell, Rebecca; Makokha, Ernest; Dobbs, Trudy; Murithi, Patrick; Muraguri, Nicholas; De Cock, Kevin M.; Mermin, Jonathan

2016-01-01

Introduction A recent infection testing algorithm (RITA) that can distinguish recent from long-standing HIV infection can be applied to nationally representative population-based surveys to characterize and identify risk factors for recent infection in a country. Materials and Methods We applied a RITA using the Limiting Antigen Avidity Enzyme Immunoassay (LAg) on stored HIV-positive samples from the 2007 Kenya AIDS Indicator Survey. The case definition for recent infection included testing recent on LAg and having no evidence of antiretroviral therapy use. Multivariate analysis was conducted to determine factors associated with recent and long-standing infection compared to HIV-uninfected persons. All estimates were weighted to adjust for sampling probability and nonresponse. Results Of 1,025 HIV-antibody-positive specimens, 64 (6.2%) met the case definition for recent infection and 961 (93.8%) met the case definition for long-standing infection. Compared to HIV-uninfected individuals, factors associated with higher adjusted odds of recent infection were living in Nairobi (adjusted odds ratio [AOR] 11.37; confidence interval [CI] 2.64–48.87) and Nyanza (AOR 4.55; CI 1.39–14.89) provinces compared to Western province; being widowed (AOR 8.04; CI 1.42–45.50) or currently married (AOR 6.42; CI 1.55–26.58) compared to being never married; having had ≥ 2 sexual partners in the last year (AOR 2.86; CI 1.51–5.41); not using a condom at last sex in the past year (AOR 1.61; CI 1.34–1.93); reporting a sexually transmitted infection (STI) diagnosis or symptoms of STI in the past year (AOR 1.97; CI 1.05–8.37); and being aged <30 years with: 1) HSV-2 infection (AOR 8.84; CI 2.62–29.85), 2) male genital ulcer disease (AOR 8.70; CI 2.36–32.08), or 3) lack of male circumcision (AOR 17.83; CI 2.19–144.90). Compared to HIV-uninfected persons, factors associated with higher adjusted odds of long-standing infection included living in Coast (AOR 1.55; CI 1.04–2

Dune formation on the Cooper Creek floodplain, Strzelecki Desert, Australia - first results of morphodynamic simulations

NASA Astrophysics Data System (ADS)

Kryger, Mateusz; Bubenzer, Olaf; Parteli, Eric

2017-04-01

Linear Dunes, which align longitudinally to the resultant wind vector, are the prevailing type of the south-north trending and partially vegetated dunes in the Strzelecki Desert, Australia. However, particularly on the Cooper Creek floodplain near Innamincka, striking complex dune features consisting of transversely oriented east-west trending dunes occur. These transverse dunes extend over several kilometers and are superimposed by linear dunes that elongate northwards and are separated by sandy swales. The aeolian features in the Strzelecki Desert are the result of interrelated late quaternary aeolian and fluvial activity and serve, thus, as archives providing information about variations in palaeoclimate and potential changes in fluvial sediment supply and wind strength and directionality. However, since the dunes are currently mostly stabilized by vegetation, it is uncertain whether their formation can be explained by the contemporary wind systems. To understand the dynamic processes underlying the genesis of the dune field in the Strzelecki Desert, the role of vegetation and the wind regimes leading to the observed dune patterns must be elucidated. Here we investigate the formative processes of the dune features occurring on the Cooper Creek floodplain by means of morphodynamic modeling of aeolian sand transport and dune formation in presence of vegetation growth. Our simulations show that a source-bordering dune can be formed out of the sediments of seasonally exposed sandbars of the palaeo-Cooper system by a unidirectional wind, which explains the emergence of the transverse dunes in the field. Moreover, a shift in the wind regime to obtuse bidirectional wind flows combined with a rapid decrease in the vegetation cover leads to the formation of linear dunes on the surface and in the lee of the transverse dunes. These linear dunes elongate over several kilometers downwind as a result of the seasonal wind changes. The dune shapes obtained in our simulations

Overview of Recent DIII-D Experimental Results

NASA Astrophysics Data System (ADS)

Fenstermacher, Max

2015-11-01

Recent DIII-D experiments have added to the ITER physics basis and to physics understanding for extrapolation to future devices. ELMs were suppressed by RMPs in He plasmas consistent with ITER non-nuclear phase conditions, and in steady state hybrid plasmas. Characteristics of the EHO during both standard high torque, and low torque enhanced pedestal QH-mode with edge broadband fluctuations were measured, including edge localized density fluctuations with a microwave imaging reflectometer. The path to Super H-mode was verified at high beta with a QH-mode edge, and in plasmas with ELMs triggered by Li granules. ITER acceptable TQ mitigation was obtained with low Ne fraction Shattered Pellet Injection. Divertor ne and Te data from Thomson Scattering confirm predicted drift-driven asymmetries in electron pressure, and X-divertor heat flux reduction and detachment were characterized. The crucial mechanisms for ExB shear control of turbulence were clarified. In collaboration with EAST, high beta-p scenarios were obtained with 80 % bootstrap fraction, high H-factor and stability limits, and large radius ITBs leading to low AE activity. Work supported by the US Department of Energy under DE-FC02-04ER54698 and DE-AC52-07NA27344.

Biofilm formation and control in a simulated spacecraft water system - Two-year results

NASA Technical Reports Server (NTRS)

Schultz, John R.; Taylor, Robert D.; Flanagan, David T.; Carr, Sandra E.; Bruce, Rebekah J.; Svoboda, Judy V.; Huls, M. H.; Sauer, Richard L.; Pierson, Duane L.

1991-01-01

The ability of iodine to maintain microbial water quality in a simulated spacecraft water system is being studied. An iodine level of about 2.0 mg/L is maintained by passing ultrapure influent water through an iodinated ion exchange resin. Six liters are withdrawn daily and the chemical and microbial quality of the water is monitored regularly. Stainless steel coupons used to monitor biofilm formation are being analyzed by culture methods, epifluorescence microscopy, and scanning electron microscopy. Results from the first two years of operation show a single episode of high bacterial colony counts in the iodinated system. This growth was apparently controlled by replacing the iodinated ion exchange resin. Scanning electron microscopy indicates that the iodine has limited but not completely eliminated the formation of biofilm during the first two years of operation. Significant microbial contamination has been present continuously in a parallel noniodinated system since the third week of operation.

Nonlinear Elastic Plate in a Flow of Gas: Recent Results and Conjectures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chueshov, Igor, E-mail: chueshov@karazin.ua; Dowell, Earl H., E-mail: dowell@duke.edu; Lasiecka, Irena, E-mail: lasiecka@memphis.edu

2016-06-15

We give a survey of recent results on flow-structure interactions modeled by a modified wave equation coupled at an interface with equations of nonlinear elasticity. Both subsonic and supersonic flow velocities are considered. The focus of the discussion here is on the interesting mathematical aspects of physical phenomena occurring in aeroelasticity, such as flutter and divergence. This leads to a partial differential equation treatment of issues such as well-posedness of finite energy solutions, and long-time (asymptotic) behavior. The latter includes theory of asymptotic stability, convergence to equilibria, and to global attracting sets. We complete the discussion with several well knownmore » observations and conjectures based on experimental/numerical studies.« less

IN-VITRO FORMATION OF PYROMORPHITE VIA REACTION OF PB SOURCES WITH SOFT-DRINK PHOSPHORIC ACID

EPA Science Inventory

Similar results were observed Pyromorphite (Pb5(PO4)3C1) is a Pb mineral whose rapid kinetic formation and thermodynamic stability (Nriagu, 1973, 1974) has gained much attention in recent years as a mechanism to diminish Pb toxicity. Our research examined the in-vitro formation o...

Characterization Of Superconducting Samples With SIC System For Thin Film Developments: Status And Recent Results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Phillips, H. Lawrence; Reece, Charles E.; Valente-Feliciano, Anne-Marie

2014-02-01

Within any thin film development program directed towards SRF accelerating structures, there is a need for an RF characterization device that can provide information about RF properties of small samples. The current installation of the RF characterization device at Jefferson Lab is Surface Impedance Characterization (SIC) system. The data acquisition environment for the system has recently been improved to allow for automated measurement, and the system has been routinely used for characterization of bulk Nb, films of Nb on Cu, MgB{sub 2}, NbTiN, Nb{sub 3}Sn films, etc. We present some of the recent results that illustrate present capabilities and limitationsmore » of the system.« less

The MACHO Project LMC Variable Star Inventory. VIII. The Recent Star Formation History of the Large Magellanic Cloud from the Cepheid Period Distribution

NASA Astrophysics Data System (ADS)

Alcock, C.; Allsman, R. A.; Alves, D. R.; Axelrod, T. S.; Becker, A. C.; Bennett, D. P.; Bersier, D. F.; Cook, K. H.; Freeman, K. C.; Griest, K.; Guern, J. A.; Lehner, M.; Marshall, S. L.; Minniti, D.; Peterson, B. A.; Pratt, M. R.; Quinn, P. J.; Rodgers, A. W.; Stubbs, C. W.; Sutherland, W.; Tomaney, A.; Vandehei, T.; Welch, D. L.

1999-02-01

We present an analysis of the period distribution of about 1800 Cepheids in the LMC, based on data obtained by the MACHO microlensing experiment and on a previous catalog by C. H. Payne Gaposchkin. Using stellar evolution and pulsation models, we construct theoretical period-frequency distributions that are compared with the observations. These models reveal that a significant burst of star formation has occurred recently in the LMC (~1.15x10^8 yr). We also show that during the last ~10^8 yr, the main center of star formation has been propagating from southeast to northwest along the bar. We find that the evolutionary masses of Cepheids are still smaller than pulsation masses by ~7% and that the red edge of the Cepheid instability strip could be slightly bluer than indicated by theory. There are approximately 600 Cepheids with periods below ~2.5 days that cannot be explained by evolution theory. We suggest that they are anomalous Cepheids and that a number of these stars are double-mode Cepheids.

Studies on the tempo of bubble formation in recently cavitated vessels: a model to predict the pressure of air bubbles.

PubMed

Wang, Yujie; Pan, Ruihua; Tyree, Melvin T

2015-06-01

A cavitation event in a vessel replaces water with a mixture of water vapor and air. A quantitative theory is presented to argue that the tempo of filling of vessels with air has two phases: a fast process that extracts air from stem tissue adjacent to the cavitated vessels (less than 10 s) and a slow phase that extracts air from the atmosphere outside the stem (more than 10 h). A model was designed to estimate how water tension (T) near recently cavitated vessels causes bubbles in embolized vessels to expand or contract as T increases or decreases, respectively. The model also predicts that the hydraulic conductivity of a stem will increase as bubbles collapse. The pressure of air bubbles trapped in vessels of a stem can be predicted from the model based on fitting curves of hydraulic conductivity versus T. The model was validated using data from six stem segments each of Acer mono and the clonal hybrid Populus 84 K (Populus alba × Populus glandulosa). The model was fitted to results with root mean square error less than 3%. The model provided new insight into the study of embolism formation in stem tissue and helped quantify the bubble pressure immediately after the fast process referred to above. © 2015 American Society of Plant Biologists. All Rights Reserved.

Studies on the Tempo of Bubble Formation in Recently Cavitated Vessels: A Model to Predict the Pressure of Air Bubbles1

PubMed Central

Wang, Yujie; Pan, Ruihua; Tyree, Melvin T.

2015-01-01

A cavitation event in a vessel replaces water with a mixture of water vapor and air. A quantitative theory is presented to argue that the tempo of filling of vessels with air has two phases: a fast process that extracts air from stem tissue adjacent to the cavitated vessels (less than 10 s) and a slow phase that extracts air from the atmosphere outside the stem (more than 10 h). A model was designed to estimate how water tension (T) near recently cavitated vessels causes bubbles in embolized vessels to expand or contract as T increases or decreases, respectively. The model also predicts that the hydraulic conductivity of a stem will increase as bubbles collapse. The pressure of air bubbles trapped in vessels of a stem can be predicted from the model based on fitting curves of hydraulic conductivity versus T. The model was validated using data from six stem segments each of Acer mono and the clonal hybrid Populus 84K (Populus alba × Populus glandulosa). The model was fitted to results with root mean square error less than 3%. The model provided new insight into the study of embolism formation in stem tissue and helped quantify the bubble pressure immediately after the fast process referred to above. PMID:25907963

The SOFIA Massive (SOMA) Star Formation Survey. I. Overview and First Results

DOE Office of Scientific and Technical Information (OSTI.GOV)

De Buizer, James M.; Shuping, Ralph; Liu, Mengyao

We present an overview and first results of the Stratospheric Observatory For Infrared Astronomy Massive (SOMA) Star Formation Survey, which is using the FORCAST instrument to image massive protostars from ∼10 to 40 μ m. These wavelengths trace thermal emission from warm dust, which in Core Accretion models mainly emerges from the inner regions of protostellar outflow cavities. Dust in dense core envelopes also imprints characteristic extinction patterns at these wavelengths, causing intensity peaks to shift along the outflow axis and profiles to become more symmetric at longer wavelengths. We present observational results for the first eight protostars in themore » survey, i.e., multiwavelength images, including some ancillary ground-based mid-infrared (MIR) observations and archival Spitzer and Herschel data. These images generally show extended MIR/FIR emission along directions consistent with those of known outflows and with shorter wavelength peak flux positions displaced from the protostar along the blueshifted, near-facing sides, thus confirming qualitative predictions of Core Accretion models. We then compile spectral energy distributions and use these to derive protostellar properties by fitting theoretical radiative transfer models. Zhang and Tan models, based on the Turbulent Core Model of McKee and Tan, imply the sources have protostellar masses m {sub *} ∼ 10–50 M {sub ⊙} accreting at ∼10{sup −4}–10{sup −3} M {sub ⊙} yr{sup −1} inside cores of initial masses M {sub c} ∼ 30–500 M {sub ⊙} embedded in clumps with mass surface densities Σ{sub cl} ∼ 0.1–3 g cm{sup −2}. Fitting the Robitaille et al. models typically leads to slightly higher protostellar masses, but with disk accretion rates ∼100× smaller. We discuss reasons for these differences and overall implications of these first survey results for massive star formation theories.« less

GNSS Remote Sensing at GFZ: Overview and Recent Results

NASA Astrophysics Data System (ADS)

Wickert, Jens; Alshawaf, Fadwa; Arras, Christina; Asgarimehr, Milad; Dick, Galina; Heise, Stefan; Larson, Kristine; Li, Xingxing; Lu, Cuixian; Peraza, Luis; Ramatschi, Markus; Schmidt, Torsten; Schuh, Harald; Semmling, Maximilian; Simeonov, Tzvetan; Vey, Sibylle; Zus, Florian

2017-04-01

GNSS atmospheric remote sensing was successfully established during the last two decades and evolved into a major application for high precision GNSS. The most prominent example for this development is the use of GNSS atmospheric data to improve day-by-day regional and global weather forecasts since 2006. Globally distributed vertical profiles of refractivity, temperature and water vapour are derived from satellite based GNSS data (Radio Occultation, RO). Ground based measurements, provided by global and regional GNSS networks, allow for the derivation of vertically (IWV) or along the line-of-sight integrated water vapour (SWV). Another important GNSS remote sensing technique, the exploitation of Earth reflected signals (GNSS Reflectometry, GNSS-R), is not yet operationally applied. But the huge potential for the determination of various physical parameters, as, e.g., sea surface height, wind speed over water and soil moisture on regional and global scales is recognized by the Earth Observation community. Therefore GNSS-R is recently a major challenge of international geophysical research. We review related activities at the German Research Centre for Geosciences GFZ and introduce recent results. The status of the GNSS-RO experiments aboard the satellites GRACE-A, TerraSAR-X and TanDEM-X, which are coordinated by GFZ, is reviewed. Examples of GNSS RO applications are given, as, e.g., climatological investigations of the global vertical temperature structure or the detection of ionospheric irregularities in the E-region. We also focus on ground based activities for GNSS water vapour monitoring. Observations of a global and regionally densified German network, with about 600 stations in total, are processed in near-real time to operationally provide IWV data. These data are assimilated into atmospheric models by several European weather centers. Current research activities are focused on the generation and meteorological application of GNSS based slant data, on real

Sequence Effect on the Formation of DNA Minidumbbells.

PubMed

Liu, Yuan; Lam, Sik Lok

2017-11-16

The DNA minidumbbell (MDB) is a recently identified non-B structure. The reported MDBs contain two TTTA, CCTG, or CTTG type II loops. At present, the knowledge and understanding of the sequence criteria for MDB formation are still limited. In this study, we performed a systematic high-resolution nuclear magnetic resonance (NMR) and native gel study to investigate the effect of sequence variations in tandem repeats on the formation of MDBs. Our NMR results reveal the importance of hydrogen bonds, base-base stacking, and hydrophobic interactions from each of the participating residues. We conclude that in the MDBs formed by tandem repeats, C-G loop-closing base pairs are more stabilizing than T-A loop-closing base pairs, and thymine residues in both the second and third loop positions are more stabilizing than cytosine residues. The results from this study enrich our knowledge on the sequence criteria for the formation of MDBs, paving a path for better exploring their potential roles in biological systems and DNA nanotechnology.

Recent results on heavy flavor physics from LEP experiments using 1990-92 data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gasparini, U.

1994-12-01

After three years of data taking, the four LEP experiments collected a total of about four million Z{sup 0} hadronic decays, in which a heavy quark pair (either b{bar b} or c{bar c}) is produced with 40% probability. Results are presented both in the sector of the electroweak precision measurements, with particular emphasis on the beauty quark, and in the determination of the beauty decay properties, where lifetimes and branching ratio measurements take advantage of the large statistics now available and of the recent improvements in the analysis based on microvertex detectors and particle identification devices.

Recent results and persisting problems in modeling flow induced coalescence

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fortelný, I., E-mail: fortelny@imc.cas.cz, E-mail: juza@imc.cas.cz; Jza, J., E-mail: fortelny@imc.cas.cz, E-mail: juza@imc.cas.cz

2014-05-15

The contribution summarizes recent results of description of the flow induced coalescence in immiscible polymer blends and addresses problems that call for which solving. The theory of coalescence based on the switch between equations for matrix drainage between spherical or deformed droplets provides a good agreement with more complicated modeling and available experimental data for probability, P{sub c}, that the collision of droplets will be followed by their fusion. A new equation for description of the matrix drainage between deformed droplets, applicable to the whole range of viscosity ratios, p, of the droplets and matrixes, is proposed. The theory facilitatesmore » to consider the effect of the matrix elasticity on coalescence. P{sub c} decreases with the matrix relaxation time but this decrease is not pronounced for relaxation times typical of most commercial polymers. Modeling of the flow induced coalescence in concentrated systems is needed for prediction of the dependence of coalescence rate on volume fraction of droplets. The effect of the droplet anisometry on P{sub c} should be studied for better understanding the coalescence in flow field with high and moderate deformation rates. A reliable description of coalescence in mixing and processing devices requires proper modeling of complex flow fields.« less

The mass-metallicity-star formation rate relation under the STARLIGHT microscope

NASA Astrophysics Data System (ADS)

Schlickmann, M.; Vale Asari, N.; Cid Fernandes, R.; Stasińska, G.

2014-10-01

The correlation between stellar mass and gas-phase oxygen abundance (M-Z relation) has been known for decades. The slope and scatter of this trend is strongly dependent on galaxy evolution: Chemical enrichment in a galaxy is driven by its star formation history, which in turn depends on its secular evolution and interaction with other galaxies and intergalactic gas. In last couple of years, the M-Z relation has been studied as a function of a third parameter: the recent star formation rate (SFR) as calibrated by the Hα luminosity, which traces stars formed in the last 10 Myr. This mass-metallicity-SFR relation has been reported to be very tight. This result puts strong constraints on galaxy evolution models in low and high redshifts, informing which models of infall and outflow of gas are acceptable. We explore the mass-metallicity-SFR relation in light of the SDSS-STARLIGHT database put together by our group. We find that we recover similar results as the ones reported by authors who use the MPA/JHU catalogue. We also present some preliminary results exploring the mass-metallicity-SFR relation in a more detailed fashion: starlight recovers a galaxy's full star formation history, and not only its recent SFR.

Recent advances in copper-catalyzed asymmetric coupling reactions

PubMed Central

2015-01-01

Summary Copper-catalyzed (or -mediated) asymmetric coupling reactions have received significant attention over the past few years. Especially the coupling reactions of aryl or alkyl halides with nucleophiles became a very powerful tool for the formation of C–C, C–N, C–O and other carbon–heteroatom bonds as well as for the construction of heteroatom-containing ring systems. This review summarizes the recent progress in copper-catalyzed asymmetric coupling reactions for the formation of C–C and carbon–heteroatom bonds. PMID:26734106

Plasma flows and magnetic field interplay during the formation of a pore

NASA Astrophysics Data System (ADS)

Ermolli, I.; Cristaldi, A.; Giorgi, F.; Giannattasio, F.; Stangalini, M.; Romano, P.; Tritschler, A.; Zuccarello, F.

2017-04-01

Aims: Recent simulations of solar magneto-convection have offered new levels of understanding of the interplay between plasma motions and magnetic fields in evolving active regions. We aim at verifying some aspects of the formation of magnetic regions derived from recent numerical studies in observational data. Methods: We studied the formation of a pore in the active region (AR) NOAA 11462. We analysed data obtained with the Interferometric Bidimensional Spectrometer (IBIS) at the Dunn Solar Telescope on April 17, 2012, consisting of full Stokes measurements of the Fe I 617.3 nm lines. Furthermore, we analysed SDO/HMI observations in the continuum and vector magnetograms derived from the Fe I 617.3 nm line data taken from April 15 to 19, 2012. We estimated the magnetic field strength and vector components and the line-of-sight (LOS) and horizontal motions in the photospheric region hosting the pore formation. We discuss our results in light of other observational studies and recent advances of numerical simulations. Results: The pore formation occurs in less than 1 h in the leading region of the AR. We observe that the evolution of the flux patch in the leading part of the AR is faster (<12 h) than the evolution (20-30 h) of the more diffuse and smaller scale flux patches in the trailing region. During the pore formation, the ratio between magnetic and dark area decreases from 5 to 2. We observe strong downflows at the forming pore boundary and diverging proper motions of plasma in the vicinity of the evolving feature that are directed towards the forming pore. The average values and trends of the various quantities estimated in the AR are in agreement with results of former observational studies of steady pores and with their modelled counterparts, as seen in recent numerical simulations of a rising-tube process. The agreement with the outcomes of the numerical studies holds for both the signatures of the flux emergence process (e.g. appearance of small

Star & Planet Formation Studies and Opportunities with SOFIA

NASA Technical Reports Server (NTRS)

Smith, Kimberly Ennico

2018-01-01

Star formation, the most fundamental process in the universe, is linked to planet formation and thus to the origin and evolution of life. We have a general outline of how planets and stars form, yet unraveling the details of the physics and chemistry continues to challenge us. The infrared and submillimeter part of the spectrum hold the most promise for studying the beginnings of star formation. The observational landscape recently shaped by Spitzer, Herschel and ALMA, continues to challenge our current theories. SOFIA, the Stratospheric Observatory for Infrared Astronomy, equipped with state-of-the-art infrared instrumentation to a vantage point at 45,000 feet (13.7 kilometers) flight altitude that is above 99.9 percent of the Earth's water vapor, enables observations in the infrared through terahertz frequencies not possible from the ground. SOFIA is a community observatory, about to start its sixth annual observing cycle. My talk will focus on recent results in advancing star and planet formation processes using SOFIA's imaging and polarimetric capabilities, and the upcoming science enabled by the 3rd generation instrument High-Resolution Mid-Infrared Spectrometer (HIRMES) to be commissioned in 2019. I will show how mid-infrared imaging is used to test massive star formation theories, how far-infrared polarimetry on sub-parsec scales is directly testing the role of magnetic fields in molecular clouds, and how velocity-resolved high-resolution spectroscopy will push forward our understanding of proto-planetary disk science. I will also summarize upcoming opportunities with the SOFIA observatory. For the latest news about your flying observatory, see https://sofia.usra.edu/.

Tunka-Rex: Status, Plans, and Recent Results

NASA Astrophysics Data System (ADS)

Schröder, F. G.; Bezyazeekov, P. A.; Budnev, N. M.; Fedorov, O.; Gress, O. A.; Haungs, A.; Hiller, R.; Huege, T.; Kazarina, Y.; Kleifges, M.; Korosteleva, E. E.; Kostunin, D.; Krömer, O.; Kungel, V.; Kuzmichev, L. A.; Lubsandorzhiev, N.; Mirgazov, R. R.; Monkhoev, R.; Osipova, E. A.; Pakhorukov, A.; Pankov, L.; Prosin, V. V.; Rubtsov, G. I.; Wischnewski, R.; Zagorodnikov, A.

2017-03-01

Tunka-Rex, the Tunka Radio extension at the TAIGA facility (Tunka Advanced Instrument for cosmic ray physics and Gamma Astronomy) in Siberia, has recently been expanded to a total number of 63 SALLA antennas, most of them distributed on an area of one square kilometer. In the first years of operation, Tunka-Rex was solely triggered by the co-located air-Cherenkov array Tunka-133. The correlation of the measurements by both detectors has provided direct experimental proof that radio arrays can measure the position of the shower maximum. The precision achieved so far is 40 g/cm2, and several methodical improvements are under study. Moreover, the cross-comparison of Tunka-Rex and Tunka-133 shows that the energy reconstruction of Tunka-Rex is precise to 15 %, with a total accuracy of 20 % including the absolute energy scale. By using exactly the same calibration source for Tunka-Rex and LOPES, the energy scale of their host experiments, Tunka-133 and KASCADE-Grande, respectively, can be compared even more accurately with a remaining uncertainty of about 10 %. The main goal of Tunka-Rex for the next years is a study of the cosmic-ray mass composition in the energy range above 100 PeV: For this purpose, Tunka-Rex now is triggered also during daytime by the particle detector array Tunka-Grande featuring surface and underground scintillators for electron and muon detection.

Biofilm formation and control in a simulated spacecraft water system - Three year results

NASA Technical Reports Server (NTRS)

Schultz, John R.; Flanagan, David T.; Bruce, Rebekah J.; Mudgett, Paul D.; Carr, Sandra E.; Rutz, Jeffrey A.; Huls, M. H.; Sauer, Richard L.; Pierson, Duane L.

1992-01-01

Two simulated spacecraft water systems are being used to evaluate the effectiveness of iodine for controlling microbial contamination within such systems. An iodine concentration of about 2.0 mg/L is maintained in one system by passing ultrapure water through an iodinated ion exchange resin. Stainless steel coupons with electropolished and mechanically-polished sides are being used to monitor biofilm formation. Results after three years of operation show a single episode of significant bacterial growth in the iodinated system when the iodine level dropped to 1.9 mg/L. This growth was apparently controlled by replacing the iodinated ion exchange resin, thereby increasing the iodine level. The second batch of resin has remained effective in controlling microbial growth down to an iodine level of 1.0 mg/L. SEM indicates that the iodine has impeded but may have not completely eliminated the formation of biofilm. Metals analyses reveal some corrosion in the iodinated system after 3 years of continuous exposure. Significant microbial contamination has been present continuously in a parallel noniodinated system since the third week of operation.

Overview of recent results from HADES

NASA Astrophysics Data System (ADS)

Lorenz, Manuel; Hades Collaboration

2017-11-01

HADES is a multi-purpose charged-particle detector operated at the SIS18 synchrotron located at the GSI Helmholtz Center for Heavy Ion Research in Darmstadt, Germany. The provided ion beam energies of 1-2 A GeV are the lowest of all currently running heavy-ion experiments and result in the highest baryo-chemical potentials at freeze-out in case of Au+Au collisions. At this Quark Matter conference we presented results from Au+Au collisions at √{sNN} = 2.4GeV. The created system exhibits a very clear hierarchy in hadron yields, with about 100 protons, 10 pions, 10-2 kaons and 10-4 antikaons per event. The HADES program focuses on four main observables: (subthreshold) strangeness production, particle flow and its anisotropies, virtual photon emission and net-proton number fluctuations.

Reconsidering formative measurement.

PubMed

Howell, Roy D; Breivik, Einar; Wilcox, James B

2007-06-01

The relationship between observable responses and the latent constructs they are purported to measure has received considerable attention recently, with particular focus on what has become known as formative measurement. This alternative to reflective measurement in the area of theory-testing research is examined in the context of the potential for interpretational confounding and a construct's ability to function as a point variable within a larger model. Although these issues have been addressed in the traditional reflective measurement context, the authors suggest that they are particularly relevant in evaluating formative measurement models. On the basis of this analysis, the authors conclude that formative measurement is not an equally attractive alternative to reflective measurement and that whenever possible, in developing new measures or choosing among alternative existing measures, researchers should opt for reflective measurement. In addition, the authors provide guidelines for researchers dealing with existing formative measures. Copyright 2007 APA, all rights reserved.

Photochemical Formation of Sulfur-Containing Aerosols

NASA Astrophysics Data System (ADS)

Kroll, Jay A.; Vaida, Veronica

2017-06-01

In order to understand planetary climate systems, modeling the properties of atmospheric aerosols is vital. Aerosol formation plays an important role in planetary climates and is tied to feedback loops that can either warm or cool a planet. Sulfur compounds are known to play an important role in new particle aerosol formation and have been observed in a number of planetary atmospheres throughout our solar system. Our current understanding of sulfur chemistry explains much of what we observe in Earth's atmosphere; however, several discrepancies arise when comparing observations of the Venusian atmosphere with model predictions. This suggests that there are still problems in our fundamental understanding of sulfur chemistry. This is concerning given recent renewed interest in sulfate injections in the stratosphere for solar radiation management geo-engineering schemes. We investigate the role of sunlight as a potential driver of the formation of sulfur-containing aerosols. I will present recent work investigating the generation of large quantities of aerosol from the irradiation of mixtures of SO_2 with water and organic species, using a solar simulator that mimics the light that is available in the Earth's troposphere and the Venusian middle atmosphere. I will present on recent work done in our lab suggesting the formation of sulfurous acid, H_2SO_3, and describe experimental work that supports this proposed mechanism. Additionally I will present on new work showing the highly reactive nature of electronically excited SO_2 with saturated alkane species. The implications of this photochemically induced sulfur aerosol formation in the atmosphere of Earth and other planetary atmospheres will be discussed.

Field test results--a new logging tool for formation density and lithology measurements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Borai, A.M.; Muhsin, M.A.

1983-03-01

The formation porosity can be determined from borehole density measurements if the density of the rock is known. Generally, this is determined from the lithology. The Litho-Density Tool, LDT, provides an improved measurement of the formation density and a new measurement of lithology. Field tests of LDT proved that the tool could be run alone in a wide range of formations to provide porosity values comparable to those obtained by running a density log combined with a neutron log.

Anaerobic Formate and Hydrogen Metabolism.

PubMed

Pinske, Constanze; Sawers, R Gary

2016-10-01

Numerous recent developments in the biochemistry, molecular biology, and physiology of formate and H2 metabolism and of the [NiFe]-hydrogenase (Hyd) cofactor biosynthetic machinery are highlighted. Formate export and import by the aquaporin-like pentameric formate channel FocA is governed by interaction with pyruvate formate-lyase, the enzyme that generates formate. Formate is disproportionated by the reversible formate hydrogenlyase (FHL) complex, which has been isolated, allowing biochemical dissection of evolutionary parallels with complex I of the respiratory chain. A recently identified sulfido-ligand attached to Mo in the active site of formate dehydrogenases led to the proposal of a modified catalytic mechanism. Structural analysis of the homologous, H2-oxidizing Hyd-1 and Hyd-5 identified a novel proximal [4Fe-3S] cluster in the small subunit involved in conferring oxygen tolerance to the enzymes. Synthesis of Salmonella Typhimurium Hyd-5 occurs aerobically, which is novel for an enterobacterial Hyd. The O2-sensitive Hyd-2 enzyme has been shown to be reversible: it presumably acts as a conformational proton pump in the H2-oxidizing mode and is capable of coupling reverse electron transport to drive H2 release. The structural characterization of all the Hyp maturation proteins has given new impulse to studies on the biosynthesis of the Fe(CN)2CO moiety of the [NiFe] cofactor. It is synthesized on a Hyp-scaffold complex, mainly comprising HypC and HypD, before insertion into the apo-large subunit. Finally, clear evidence now exists indicating that Escherichia coli can mature Hyd enzymes differentially, depending on metal ion availability and the prevailing metabolic state. Notably, Hyd-3 of the FHL complex takes precedence over the H2-oxidizing enzymes.

Achievement Goal Orientations and Identity Formation Styles

ERIC Educational Resources Information Center

Kaplan, Avi; Flum, Hanoch

2010-01-01

The present article points to shared underlying theoretical assumptions and central processes of a prominent academic motivation perspective--achievement goal theory--and recent process perspectives in the identity formation literature, and more specifically, identity formation styles. The review highlights the shared definition of achievement…

NASA Ames’ COSmIC Laboratory Astrophysics Facility: Recent Results and Progress

NASA Astrophysics Data System (ADS)

Salama, Farid; Sciamma-O'Brien, Ella; Bejaoui, Salma

2018-06-01

The COSmIC facility was developed at NASA Ames to study interstellar, circumstellar and planetary analogs in the laboratory [1, 2]. COSmIC stands for “Cosmic Simulation Chamber” and is dedicated to the study of molecules, ions and nanoparticles under the low temperature and high vacuum conditions that are required to simulate space environments. COSmIC integrates a variety of instruments that allow generating; processing and monitoring simulated space conditions in the laboratory. It is composed of a Pulsed Discharge Nozzle expansion that generates a plasma in a free supersonic jet expansion coupled to high-sensitivity, complementary in situ diagnostic tools, used for the detection and characterization of the species present in the expansion: a Cavity Ring Down Spectroscopy (CRDS) and fluorescence spectroscopy systems for photonic detection, and a Reflectron Time-Of-Flight Mass Spectrometer (ReTOF-MS) for mass detection [3, 4].Recent advances achieved in laboratory astrophysics using COSmIC will be presented, in particular in the domain of the diffuse interstellar bands (DIBs) [5, 6] and the monitoring, in the laboratory, of the formation of dust grains and aerosols from their gas-phase molecular precursors in environments as varied as circumstellar outflows [7] and planetary atmospheres [8, 9, 10]. Plans for future laboratory experiments on cosmic molecules and grains in the growing field of laboratory astrophysics (NIR-MIR CRDS, Laser Induced Fluorescence spectra of cosmic molecule analogs and the laser induced incandescence spectra of cosmic grain analogs) will also be addressed as well as the implications for astronomy.References: [1] Salama F., Proceed. IAU S251, Kwok & Sandford eds. CUP, 4, 357 (2008).[2] Salama F., et al., Proceed. IAU S332, Y. Aikawa, M. Cunningham, T. Millar, eds., CUP (2018)[3] Biennier L., et al., J. Chem. Phys., 118, 7863 (2003)[4] Ricketts C. et al. IJMS, 300, 26 (2011)[5] Salama F., et al., ApJ., 728, 154 (2011)[6] EDIBLES

The Panchromatic Hubble Andromeda Treasury. XI. The Spatially Resolved Recent Star Formation History of M31

NASA Astrophysics Data System (ADS)

Lewis, Alexia R.; Dolphin, Andrew E.; Dalcanton, Julianne J.; Weisz, Daniel R.; Williams, Benjamin F.; Bell, Eric F.; Seth, Anil C.; Simones, Jacob E.; Skillman, Evan D.; Choi, Yumi; Fouesneau, Morgan; Guhathakurta, Puragra; Johnson, Lent C.; Kalirai, Jason S.; Leroy, Adam K.; Monachesi, Antonela; Rix, Hans-Walter; Schruba, Andreas

2015-06-01

We measure the recent star formation history (SFH) across M31 using optical images taken with the Hubble Space Telescope as part of the Panchromatic Hubble Andromeda Treasury (PHAT). We fit the color-magnitude diagrams in ˜9000 regions that are ˜100 pc × 100 pc in projected size, covering a 0.5 square degree area (˜380 kpc2, deprojected) in the NE quadrant of M31. We show that the SFHs vary significantly on these small spatial scales but that there are also coherent galaxy-wide fluctuations in the SFH back to ˜500 Myr, most notably in M31's 10 kpc star-forming ring. We find that the 10 kpc ring is at least 400 Myr old, showing ongoing star formation (SF) over the past ˜500 Myr. This indicates the presence of molecular gas in the ring over at least 2 dynamical times at this radius. We also find that the ring’s position is constant throughout this time, and is stationary at the level of 1 km s-1, although there is evidence for broadening of the ring due to the diffusion of stars into the disk. Based on existing models of M31's ring features, the lack of evolution in the ring’s position makes a purely collisional ring origin highly unlikely. Besides the well-known 10 kpc ring, we observe two other ring-like features. There is an outer ring structure at 15 kpc with concentrated SF starting ˜80 Myr ago. The inner ring structure at 5 kpc has a much lower star formation rate (SFR) and therefore lower contrast against the underlying stellar disk. It was most clearly defined ˜200 Myr ago, but is much more diffuse today. We find that the global SFR has been fairly constant over the last ˜500 Myr, though it does show a small increase at 50 Myr that is 1.3 times the average SFR over the past 100 Myr. During the last ˜500 Myr, ˜60% of all SF has occurred in the 10 kpc ring. Finally, we find that in the past 100 Myr, the average SFR over the PHAT survey area is 0.28 ± 0.03 {{M}⊙ } y{{r}-1} with an average deprojected intensity of 7.3× {{10}-4} {{M}⊙ } y

Advanced turboprop noise prediction based on recent theoretical results

NASA Technical Reports Server (NTRS)

Farassat, F.; Padula, S. L.; Dunn, M. H.

1987-01-01

The development of a high speed propeller noise prediction code at Langley Research Center is described. The code utilizes two recent acoustic formulations in the time domain for subsonic and supersonic sources. The structure and capabilities of the code are discussed. Grid size study for accuracy and speed of execution on a computer is also presented. The code is tested against an earlier Langley code. Considerable increase in accuracy and speed of execution are observed. Some examples of noise prediction of a high speed propeller for which acoustic test data are available are given. A brisk derivation of formulations used is given in an appendix.

Reconsidering Formative Measurement

ERIC Educational Resources Information Center

Howell, Roy D.; Breivik, Einar; Wilcox, James B.

2007-01-01

The relationship between observable responses and the latent constructs they are purported to measure has received considerable attention recently, with particular focus on what has become known as formative measurement. This alternative to reflective measurement in the area of theory-testing research is examined in the context of the potential…

Recent results on search for new physics at BaBar

NASA Astrophysics Data System (ADS)

Oberhof, Benjamin

2017-04-01

We present some recent measurements for the search of New Physics using 514 fb-1 of e+e- collisions collected with the BaBar detector at the PEP-II e+e- collider at SLAC. First we present a search for the decay ϒ (1S) → γA0, A0 → cc¯, where A0 is a candidate for the CP-odd Higgs boson of the next-to-minimal supersymmetric standard model. No significant signal is observed and we set 90% confidence-level upper limits on B(ϒ(1S ) → γA0) × B(A0 → cc¯). We report the search for a light non-Standard Model gauge boson Z' coupling only to the second and third lepton families. Our results significantly improve current limits and further constrain the remaining region of the allowed parameter space. Finally, we present a search for a long-lived particle L that is produced in e+e- annihilations and decays into two oppositely charged tracks. We do not observe a significant signal and we and set 90% confidence level upper limits on the product of the L production cross section, branching fraction, and reconstruction efficiency as a function of the L mass. In addition, upper limits are provided on the branching fraction B(B → XsL), where Xs is an hadronic system with strangeness -1.

The Status and Recent Results of the Telescope Array Experiment

NASA Astrophysics Data System (ADS)

Yamazaki, Katsuya

The Telescope Array (TA) is a cosmic ray observatory of the largest aperture in the northern hemisphere, located in a desert in the western part of Utah, U.S.A., to explore the origin of ultrahigh energy cosmic rays, photons, and neutrinos. The TA employs two types of detectors to observe air showers generated by cosmic rays in the atmosphere: the first is a "surface detector (SD)" of scintillation counters to measure shower particles on the ground, and the second is a "fluorescence detector (FD)" of telescopes installed in three stations to observe fluorescence light, caused by air shower particles, from the atmosphere above the SD array. The TA detectors have been in routine operation since May 2008. We measured the energy spectrum of cosmic rays with energy greater than 1018 eV from our first 4-year data. We found a clear suppression of comic ray intensity above 5 × 1019 eV. This feature is consistent with a theoretical prediction that cosmic rays lose energies due to interaction with cosmic microwave background photons during propagation in the intergalactic space. In this talk, We will present the status of the TA experiment and the recent results, including the energy spectrum, study of the primary mass composition, and searches for anisotropies in the arrival directions. We also briefly describe plans for further extensions.

Recent bed rest results and countermeasure development at NASA

NASA Technical Reports Server (NTRS)

Hargens, A. R.

1994-01-01

Bedrest studies of normal subjects provide opportunities to understand physiologic responses to supine posture and inactivity. Furthermore, head-down tilt has been a valuable procedure to investigate adaptation to microgravity and development of countermeasures to maintain the health and well-being of humans during space-flight. Recent bedrest experiments at NASA have ranged in duration from a few hours to 17 weeks. Acute studies of 6 degrees head-down tilt indicate that elevation of capillary blood pressure from 28 to 34 mm Hg and increased capillary perfusion in tissues of the head cause facial and intracranial edema. Intracranial pressure increases from 2 to 17 mm Hg going from upright posture to 6 degrees head-down tilt. Microvessels of the head have a low capacity to constrict and diminish local perfusion. Elevation of blood and tissue fluid pressures/flow in the head may also explain the higher headward bone density associated with long-term head-down tilt. These mechanistic studies of head-down tilt, along with a better understanding of the relative stresses involved with upright posture and lower body negative pressure, have facilitated development of suitable physiologic countermeasures to maintain astronaut health during microgravity. Presently no exercise hardware is available to provide a blood pressure gradient from head to feet in space. However, recent studies in our laboratory suggest that treadmill exercise using a graded lower-body compression suit and 100 mmHg lower body negative pressure provides equivalent or greater physiologic stress than similar upright exercise on Earth. Therefore, exercise within a lower body negative pressure chamber may provide a cost-effective and simple countermeasure to maintain the cardiovascular and neuro-musculoskeletal systems of astronauts during long-duration flight.

Diagnostic impact of routine Lyme serology in recent-onset arthritis: results from the ESPOIR cohort

PubMed Central

Guellec, Dewi; Narbonne, Valérie; Cornec, Divi; Marhadour, Thierry; Varache, Sophie; Dougados, Maxime; Daurès, Jean Pierre; Jousse-Joulin, Sandrine; Devauchelle-Pensec, Valérie; Saraux, Alain

2016-01-01

Objectives Lyme disease may be considered by rheumatologists in patients with recent-onset arthritis, even in the absence of suggestive symptoms. The aim of this study was to determine the diagnostic impact of routine Lyme serology in a French cohort of patients with recent-onset arthritis affecting at least 2 joints. Methods We performed an ancillary study of a French prospective multicentre cohort established to monitor clinical, biological and radiographic data in patients with inflammatory arthritis in at least 2 joints, lasting for 6 weeks to 6 months. Borrelia IgM and IgG antibodies were sought routinely at baseline, using ELISA tests, independently from the physician's strategy for detecting a spirochetal infection. We recorded the proportion of patients with a final diagnosis of Lyme arthritis and evaluated the diagnostic performance of Lyme serology in this particular context. The clinical and biological characteristics of patients according to the Lyme serology results were analysed. Results Of 810 patients, 657 (81.1%) were negative for IgM and IgG antibodies, 91 (11.2%) had only IgM antibodies, 49 (6%) had only IgG antibodies, and 13 (1.6%) had IgG and IgM antibodies. Thus, 7.6% had IgG positivity, consistent with exposure to Borrelia infection. IgG positivity was significantly more prevalent in the North and North-East regions of France (χ2=14.6, p<0.001). No patients received a definite diagnosis of Lyme arthritis. Conclusions This study does not support routine Lyme serological testing in patients with recent-onset inflammatory arthritis affecting more than 1 joint. PMID:26819751

Investigations of a Combustor Using a 9-Point Swirl-Venturi Fuel Injector: Recent Experimental Results

NASA Technical Reports Server (NTRS)

Hicks, Yolanda R.; Heath, Christopher M.; Anderson, Robert C.; Tacina, Kathleen M.

2012-01-01

This paper explores recent results obtained during testing in an optically-accessible, JP8-fueled, flame tube combustor using baseline Lean Direct Injection (LDI) research hardware. The baseline LDI geometry has nine fuel/air mixers arranged in a 3 x 3 array. Results from this nine-element array include images of fuel and OH speciation via Planar Laser-Induced Fluorescence (PLIF), which describe fuel spray pattern and reaction zones. Preliminary combustion temperatures derived from Stokes/Anti-Stokes Spontaneous Raman Spectroscopy are also presented. Other results using chemiluminescence from major combustion radicals such as CH* and C2* serve to identify the primary reaction zone, while OH PLIF shows the extent of reaction further downstream. Air and fuel velocities and fuel drop size results are also reported.

Recent results from WASA-at-COSY

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hejny, V.

2010-12-28

WASA--a 4{pi} spectrometer for detection of charged and neutral particles--started operation at the cooler synchrotron COSY-Juelich in 2007. A number of experiments on meson production and decays have been carried out since then. The status of the analysis and preliminary results of some selected topics from the physics program are discussed.

Formation of banded vegetation patterns resulted from interactions between sediment deposition and vegetation growth.

PubMed

Huang, Tousheng; Zhang, Huayong; Dai, Liming; Cong, Xuebing; Ma, Shengnan

2018-03-01

This research investigates the formation of banded vegetation patterns on hillslopes affected by interactions between sediment deposition and vegetation growth. The following two perspectives in the formation of these patterns are taken into consideration: (a) increased sediment deposition from plant interception, and (b) reduced plant biomass caused by sediment accumulation. A spatial model is proposed to describe how the interactions between sediment deposition and vegetation growth promote self-organization of banded vegetation patterns. Based on theoretical and numerical analyses of the proposed spatial model, vegetation bands can result from a Turing instability mechanism. The banded vegetation patterns obtained in this research resemble patterns reported in the literature. Moreover, measured by sediment dynamics, the variation of hillslope landform can be described. The model predicts how treads on hillslopes evolve with the banded patterns. Thus, we provide a quantitative interpretation for coevolution of vegetation patterns and landforms under effects of sediment redistribution. Copyright © 2018. Published by Elsevier Masson SAS.

Community Agency Survey Formative Research Results from the TAAG Study

ERIC Educational Resources Information Center

Saunders, Ruth P.; Moody, Jamie

2006-01-01

School and community agency collaboration can potentially increase physical activity opportunities for youth. Few studies have examined the role of community agencies in promoting physical activity, much less in collaboration with schools. This article describes formative research data collection from community agencies to inform the development…

Planet Formation

NASA Technical Reports Server (NTRS)

Lissauer, Jack J.; Young, Richard E. (Technical Monitor)

1997-01-01

Modern theories of star and planet formation, which are based upon observations of the Solar System and of young stars and their environments, predict that most single stars should have rocky planets in orbit about them; the frequency of gas giant planets is more difficult to predict theoretically. Terrestrial planets are believed to grow via pairwise accretion until the spacing of planetary orbits becomes large enough that the configuration is stable for the age of the system. Giant planets begin their growth like terrestrial planets, but they become massive enough that they are able to accumulate substantial amounts of gas before the protoplanetary disk dissipates. Models for the formation of the giant planets found in recent radial velocity searches are discussed.

The formation of topological defects in phase transitions

NASA Technical Reports Server (NTRS)

Hodges, Hardy M.

1989-01-01

It was argued, and fought through numerical work that the results of non-dynamical Monte Carlo computer simulations cannot be applied to describe the formation of topological defects when the correlation length at the Ginzburg temperature is significantly smaller than the horizon size. To test the current hypothesis that infinite strings at formation are essentially described by Brownian walks of size the correlation length at the Ginzburg temperature, fields at the Ginzburg temperature were equilibrated. Infinite structure do not exist in equilibrium for reasonable definitions of the Ginzburg temperature, and horizons must be included in a proper treatment. A phase transition, from small-scale to large-scale string or domain wall structure, is found to occur very close to the Ginzburg temperature, in agreement with recent work. The formation process of domain walls and global strings were investigated through the breaking of initially ordered states. To mimic conditions in the early Universe, cooling times are chosen so that horizons exist in the sample volume when topological structure formation occurs. The classical fields are evolved in real-time by the numerical solution of Langevin equations of motion on a three dimensional spatial lattice. The results indicate that it is possible for most of the string energy to be in small loops, rather than in long strings, at formation.

CHARACTERIZING THE STAR FORMATION OF THE LOW-MASS SHIELD GALAXIES FROM HUBBLE SPACE TELESCOPE IMAGING

DOE Office of Scientific and Technical Information (OSTI.GOV)

McQuinn, Kristen B. W.; Skillman, Evan D.; Simones, Jacob E.

The Survey of Hi in Extremely Low-mass Dwarfs is an on-going multi-wavelength program to characterize the gas, star formation, and evolution in gas-rich, very low-mass galaxies that populate the faint end of the galaxy luminosity function. The galaxies were selected from the first ∼10% of the Hi Arecibo Legacy Fast ALFA survey based on their low Hi mass and low baryonic mass. Here, we measure the star formation properties from optically resolved stellar populations for 12 galaxies using a color–magnitude diagram fitting technique. We derive lifetime average star formation rates (SFRs), recent SFRs, stellar masses, and gas fractions. Overall, themore » recent SFRs are comparable to the lifetime SFRs with mean birthrate parameter of 1.4, with a surprisingly narrow standard deviation of 0.7. Two galaxies are classified as dwarf transition galaxies (dTrans). These dTrans systems have star formation and gas properties consistent with the rest of the sample, in agreement with previous results that some dTrans galaxies may simply be low-luminosity dwarf irregulars. We do not find a correlation between the recent star formation activity and the distance to the nearest neighboring galaxy, suggesting that the star formation process is not driven by gravitational interactions, but regulated internally. Further, we find a broadening in the star formation and gas properties (i.e., specific SFRs, stellar masses, and gas fractions) compared to the generally tight correlation found in more massive galaxies. Overall, the star formation and gas properties indicate these very low-mass galaxies host a fluctuating, non-deterministic, and inefficient star formation process.« less

Sensitive strata in Bootlegger Cove Formation

USGS Publications Warehouse

Olsen, Harold W.

1989-01-01

Sensitivity magnitudes are interpreted from remolded strength values in recent subsurface geologic, geotechnical, and geochemical data from the Bootlegger Cove Formation adjacent to the Turnagain Heights Landslide. The results show that strata composed of highly sensitive clays occur in both the middle and lower zones of the formation, and that between these strata the clays are generally of low-to-medium sensitivity. The most sensitive stratum is in the middle zone between two sand layers, and its sensitivity increases from both clay-sand interfaces to a maximum at the center of the stratum. The pore fluid chemistry of the highly sensitive materials differs from that in the materials of low to medium sensitivity only in their concentrations of organic carbon, chloride, bicarbonate, and sulfate. The total dissolved solids concentration is low, and the ratio of monovalent to divalent cations is very high throughout the middle and lower zones of the formation. Of the known causes of high and extremely high sensitivities, only organic and/or anionic dispersants are consistent with these findings.

Abiotic methane formation during experimental serpentinization of olivine

PubMed Central

2016-01-01

Fluids circulating through actively serpentinizing systems are often highly enriched in methane (CH4). In many cases, the CH4 in these fluids is thought to derive from abiotic reduction of inorganic carbon, but the conditions under which this process can occur in natural systems remain unclear. In recent years, several studies have reported abiotic formation of CH4 during experimental serpentinization of olivine at temperatures at or below 200 °C. However, these results seem to contradict studies conducted at higher temperatures (300 °C to 400 °C), where substantial kinetic barriers to CH4 synthesis have been observed. Here, the potential for abiotic formation of CH4 from dissolved inorganic carbon during olivine serpentinization is reevaluated in a series of laboratory experiments conducted at 200 °C to 320 °C. A 13C-labeled inorganic carbon source was used to unambiguously determine the origin of CH4 generated in the experiments. Consistent with previous high-temperature studies, the results indicate that abiotic formation of CH4 from reduction of dissolved inorganic carbon during the experiments is extremely limited, with nearly all of the observed CH4 derived from background sources. The results indicate that the potential for abiotic synthesis of CH4 in low-temperature serpentinizing environments may be much more limited than some recent studies have suggested. However, more extensive production of CH4 was observed in one experiment performed under conditions that allowed an H2-rich vapor phase to form, suggesting that shallow serpentinization environments where a separate gas phase is present may be more favorable for abiotic synthesis of CH4. PMID:27821742

Abiotic methane formation during experimental serpentinization of olivine.

PubMed

McCollom, Thomas M

2016-12-06

Fluids circulating through actively serpentinizing systems are often highly enriched in methane (CH 4 ). In many cases, the CH 4 in these fluids is thought to derive from abiotic reduction of inorganic carbon, but the conditions under which this process can occur in natural systems remain unclear. In recent years, several studies have reported abiotic formation of CH 4 during experimental serpentinization of olivine at temperatures at or below 200 °C. However, these results seem to contradict studies conducted at higher temperatures (300 °C to 400 °C), where substantial kinetic barriers to CH 4 synthesis have been observed. Here, the potential for abiotic formation of CH 4 from dissolved inorganic carbon during olivine serpentinization is reevaluated in a series of laboratory experiments conducted at 200 °C to 320 °C. A 13 C-labeled inorganic carbon source was used to unambiguously determine the origin of CH 4 generated in the experiments. Consistent with previous high-temperature studies, the results indicate that abiotic formation of CH 4 from reduction of dissolved inorganic carbon during the experiments is extremely limited, with nearly all of the observed CH 4 derived from background sources. The results indicate that the potential for abiotic synthesis of CH 4 in low-temperature serpentinizing environments may be much more limited than some recent studies have suggested. However, more extensive production of CH 4 was observed in one experiment performed under conditions that allowed an H 2 -rich vapor phase to form, suggesting that shallow serpentinization environments where a separate gas phase is present may be more favorable for abiotic synthesis of CH 4 .

N-nitrosodimethylamine (NDMA) formation from the ozonation of model compounds.

PubMed

Marti, Erica J; Pisarenko, Aleksey N; Peller, Julie R; Dickenson, Eric R V

2015-04-01

Nitrosamines are a class of toxic disinfection byproducts commonly associated with chloramination, of which several were included on the most recent U.S. EPA Contaminant Candidate List. Nitrosamine formation may be a significant barrier to ozonation in water reuse applications, particularly for direct or indirect potable reuse, since recent studies show direct formation during ozonation of natural water and treated wastewaters. Only a few studies have identified precursors which react with ozone to form N-nitrosodimethylamine (NDMA). In this study, several precursor compound solutions, prepared in ultrapure water and treated wastewater, were subjected to a 10 M excess of ozone. In parallel experiments, the precursor solutions in ultrapure water were exposed to gamma radiation to determine NDMA formation as a byproduct of reactions of precursor compounds with hydroxyl radicals. The results show six new NDMA precursor compounds that have not been previously reported in the literature, including compounds with hydrazone and carbamate moieties. Molar yields in deionized water were 61-78% for 3 precursors, 12-23% for 5 precursors and <4% for 2 precursors. Bromide concentration was important for three compounds (1,1-dimethylhydrazine, acetone dimethylhydrazone and dimethylsulfamide), but did not enhance NDMA formation for the other precursors. NDMA formation due to chloramination was minimal compared to formation due to ozonation, suggesting distinct groups of precursor compounds for these two oxidants. Hydroxyl radical reactions with the precursors will produce NDMA, but formation is much greater in the presence of molecular ozone. Also, hydroxyl radical scavenging during ozonation leads to increased NDMA formation. Molar conversion yields were higher for several precursors in wastewater as compared to deionized water, which could be due to catalyzed reactions with constituents found in wastewater or hydroxyl radical scavenging. Copyright © 2014 Elsevier Ltd. All

Coronal Mass Ejections: a Summary of Recent Results

NASA Technical Reports Server (NTRS)

Gopalswamy, Nat; Davila, J. M.

2010-01-01

Coronal mass ejections (CMEs) have been recognized as the most energetic phenomenon in the heliosphere, deriving their energy from the stressed magnetic fields on the Sun. This paper highlights some of the recent results on CMEs obtained from the Solar and Heliospheric Observatory (SOHO) and the Solar Terrestrial Relations Observatory (STEREO) missions. The summary of the talk follows. SOHO observations revealed that the CME rate is almost a factor of two larger than previously thought and varied with the solar activity cycle in a complex way (e.g., high-latitude CMEs occurred in great abundance during the solar maximum years). CMEs were found to interact with other CMEs as well as with other large-scale structures (coronal holes), resulting in deflections and additional particle acceleration. STEREO observations have confirmed the three-dimensional nature of CMEs and the shocks surrounding them. The EUV signatures (flare arcades, corona) dimming, filament eruption, and EUV waves) associated with CMEs have become vital in the identification of solar sources from which CMEs erupt. CMEs with speeds exceeding the characteristic speeds of the corona and the interplanetary medium drive shocks, which produce type II radio bursts. The wavelength range of type II bursts depends on the CME kinetic energy: type II bursts with emission components at all wavelengths (metric to kilometric) are due to CMEs of the highest kinetic energy. Some CMEs, as fast as 1600 km/s do not produce type II bursts, while slow CMEs (400 km/s) occasionally produce type II bursts. These observations can be explained as the variation in the ambient flow speed (solar wind) and the Alfven speed. Not all CME-driven shocks produce type II bursts because either they are subcritical or do not have the appropriate geometry. The same shocks that produce type II bursts also produce solar energetic particles (SEPs), whose release near the Sun seems to be delayed with respect to the onset of type II bursts

Impact-Induced Clay Mineral Formation and Distribution on Mars

NASA Technical Reports Server (NTRS)

Rivera-Valentin, E. G.; Craig, P. I.

2015-01-01

Clay minerals have been identified in the central peaks and ejecta blankets of impact craters on Mars. Several studies have suggested these clay minerals formed as a result of impact induced hydrothermalism either during Mars' Noachian era or more recently by the melting of subsurface ice. Examples of post-impact clay formation is found in several locations on Earth such as the Mjolnir and Woodleigh Impact Structures. Additionally, a recent study has suggested the clay minerals observed on Ceres are the result of impact-induced hydrothermal processes. Such processes may have occurred on Mars, possibly during the Noachian. Distinguishing between clay minerals formed preor post-impact can be accomplished by studying their IR spectra. In fact, showed that the IR spectra of clay minerals is greatly affected at longer wavelengths (i.e. mid-IR, 5-25 micron) by impact-induced shock deformation while the near-IR spectra (1.0-2.5 micron) remains relatively unchanged. This explains the discrepancy between NIR and MIR observations of clay minerals in martian impact craters noted. Thus, it allows us to determine whether a clay mineral formed from impact-induced hydrothermalism or were pre-existing and were altered by the impact. Here we study the role of impacts on the formation and distribution of clay minerals on Mars via a fully 3-D Monte Carlo cratering model, including impact- melt production using results from modern hydrocode simulations. We identify regions that are conducive to clay formation and the location of clay minerals post-bombardment.

Summary and recent results from the NASA advanced High Speed Propeller Research Program

NASA Technical Reports Server (NTRS)

Mitchell, G. A.; Mikkelson, D. C.

1982-01-01

Advanced high-speed propellers offer large performance improvements for aircraft that cruise in the Mach 0.7 to 0.8 speed regime. The current status of the NASA research program on high-speed propeller aerodynamics, acoustics, and aeroelastics is described. Recent wind tunnel results for five 8- to 10-blade advanced models are compared with analytical predictions. Test results show that blade sweep was important in achieving net efficiencies near 80 percent at Mach 0.8 and reducing near-field cruise noise by dB. Lifting line and lifting surface aerodynamic analysis codes are under development and some initial lifting line results are compared with propeller force and probe data. Some initial laser velocimeter measurements of the flow field velocities of an 8-bladed 45 deg swept propeller are shown. Experimental aeroelastic results indicate that cascade effects and blade sweep strongly affect propeller aeroelastic characteristics. Comparisons of propeller near-field noise data with linear acoustic theory indicate that the theory adequate predicts near-field noise for subsonic tip speeds but overpredicts the noise for supersonic tip speeds. Potential large gains in propeller efficiency of 7 to 11 percent at Mach 0.8 may be possible with advanced counter-rotation propellers.

Cluster formation and phase separation in heteronuclear Janus dumbbells

NASA Astrophysics Data System (ADS)

Munaò, G.; O'Toole, P.; Hudson, T. S.; Costa, D.; Caccamo, C.; Sciortino, F.; Giacometti, A.

2015-06-01

We have recently investigated the phase behavior of model colloidal dumbbells constituted by two identical tangent hard spheres, with the first being surrounded by an attractive square-well interaction (Janus dumbbells, Munaó et al 2014 Soft Matter 10 5269). Here we extend our previous analysis by introducing in the model the size asymmetry of the hard-core diameters and study the enriched phase scenario thereby obtained. By employing standard Monte Carlo simulations we show that in such ‘heteronuclear Janus dumbbells’ a larger hard-sphere site promotes the formation of clusters, whereas in the opposite condition a gas-liquid phase separation takes place, with a narrow interval of intermediate asymmetries wherein the two phase behaviors may compete. In addition, some peculiar geometrical arrangements, such as lamellæ, are observed only around the perfectly symmetric case. A qualitative agreement is found with recent experimental results, where it is shown that the roughness of molecular surfaces in heterogeneous dimers leads to the formation of colloidal micelles.

Model for interface formation and the resulting electrical properties for barium-strontium-titanate films on silicon

NASA Astrophysics Data System (ADS)

Mueller, A. H.; Suvorova, N. A.; Irene, E. A.; Auciello, O.; Schultz, J. A.

2003-04-01

The interface formation between sputtered barium strontium titanate (BST) films and both Si and SiO2 substrate surfaces has been followed using real-time spectroscopic ellipsometry and the mass spectrometry of recoiled ions. In both substrates an intermixed interface layer was observed and subcutaneous Si oxidation occurred. A model for the interface formation is proposed in which the interface includes an SiO2 film on Si, and an intermixed film on which is pure BST. During the deposition of BST the interfaces films were observed to change in time. Electrical characterization of the resulting metal-BST interface capacitors indicates that those samples with SiO2 on the Si surface had the best electrical characteristics.

GBSFP: General Bluetooth Scatternet Formation Protocol for Ad Hoc Networking

NASA Astrophysics Data System (ADS)

Lim, Chaegwon; Huh, Myung-Sun; Choi, Chong-Ho; Jeong, Gu-Min

Recently, bluetooth technology has become widely prevalent so that many laptops and mobile phones are equipped with bluetooth capability. In order to meet the increasing demand to interconnect these devices a new scatternet formation protocol named GBSFP (General Bluetooth Scatternet Formation Protocol) is proposed in this paper. GBSFP is the result of efforts to overcome the two major limitations of the legacy scatternet formation protocols as regards their real implementation, that all of the nodes should be within the Bluetooth communication range or that they should be time synchronized. In GBSFP, a node goes through three phases; 1) the Init phase to establish a bluetooth link to as many of its neighbors as possible, 2) the Ready phase to determine the role of each node, i.e., master or slave, and remove any unnecessary bluetooth links, and 3) the Complete phase to finalize the formation of the scatternet and begin data transmission. The simulation results show that GBSFP provides higher connectivity in many scenarios compared with BTCP and BlueStars.

Learning Group Formation Based on Learner Profile and Context

ERIC Educational Resources Information Center

Muehlenbrock, Martin

2006-01-01

An important but often neglected aspect in Computer-Supported Collaborative Learning (CSCL) is the formation of learning groups. Until recently, most support for group formation was based on learner profile information. In addition, the perspective of ubiquitous computing and ambient intelligence allows for a wider perspective on group formation,…

Microsomal Metabolism of Prochiral Polychlorinated Biphenyls Results in the Enantioselective Formation of Chiral Metabolites

PubMed Central

2016-01-01

Polychlorinated biphenyl (PCB) congeners with multiple ortho chlorine substituents and their metabolites exist as stable rotational isomers, or atropisomers, that are nonsuperimposable mirror images of each other. Additionally, the oxidation of certain axially prochiral PCBs, such as 2,2′,4,6′-tetrachlorobiphenyl (PCB 51) and 2,2′,4,5,6′-pentachlorobiphenyl (PCB 102), in the meta position of the symmetrically substituted phenyl ring is expected to form axially chiral hydroxylated metabolites (OH-PCBs); however, the formation of chiral OH-PCBs from prochiral PCBs has not been demonstrated experimentally. Here, we investigate if the oxidation of PCB 51 and PCB 102 by different microsomal preparations results in the formation of chiral OH-PCBs. Gas chromatographic analysis revealed that PCB 51 and PCB 102 were metabolized to 2,2′,4,6′-tetrachlorobiphenyl-3′-ol (OH-PCB 51) and 2,2′,4,5,6′-pentachlorobiphenyl-3′-ol (OH-PCB 102), respectively, by liver microsomes from male rats pretreated with different inducers; untreated male monkeys, guinea pigs, rabbits, and hamsters; and female dogs. The formation of both metabolites was inducer- and species-dependent. Both OH-PCB 51 and OH-PCB 102 were chiral and formed enantioselectively by all microsomal preparations investigated. These findings demonstrate that axially chiral PCB metabolites are formed from axially prochiral PCB congeners, a fact that should be considered when studying the environmental fate, transport, and toxicity of OH-PCBs. PMID:28038482

Sugars, obesity, and cardiovascular disease: results from recent randomized control trials.

PubMed

Rippe, James M; Angelopoulos, Theodore J

2016-11-01

The relationship between sugar consumption and various health-related sequelas is controversial. Some investigators have argued that excessive sugar consumption is associated with increased risk of obesity, coronary heart disease, diabetes (T2D), metabolic syndrome, non-alcoholic fatty liver disease, and stimulation of reward pathways in the brain potentially causing excessive caloric consumption. These concerns have influenced organizations such as the World Health Organization, the Scientific Advisory Committee on Nutrition in England not to exceed 5 % of total energy and the Dietary Guidelines for Americans Advisory Committee 2015 to recommend upper limits of sugar consumption not to exceed 10 % of calories. Data from many randomized control trials (RCTs) do not support linkages between sugar consumption at normal levels within the human diet and various adverse metabolic and health-related effects. Fructose and glucose are typically consumed together in roughly equal proportions from high-fructose corn syrup (also known as isoglucose in Europe) or sucrose. The purpose of this review is to present data from recent RCTs and findings from recent systematic reviews and meta-analyses related to sugar consumption and its putative health effects. This review evaluates findings from recent randomized controlled trials, systematic reviews and meta-analyses into the relationship of sugar consumption and a range of health-related issues including energy-regulating hormones, obesity, cardiovascular disease, diabetes, and accumulation of liver fat and neurologic responses. Data from these sources do not support linkages between sugar consumption at normal levels within the human diet and various adverse metabolic and health-related effects.

Wood formation in Angiosperms.

PubMed

Déjardin, Annabelle; Laurans, Françoise; Arnaud, Dominique; Breton, Christian; Pilate, Gilles; Leplé, Jean-Charles

2010-04-01

Wood formation is a complex biological process, involving five major developmental steps, including (1) cell division from a secondary meristem called the vascular cambium, (2) cell expansion (cell elongation and radial enlargement), (3) secondary cell wall deposition, (4) programmed cell death, and (5) heartwood formation. Thanks to the development of genomic studies in woody species, as well as genetic engineering, recent progress has been made in the understanding of the molecular mechanisms underlying wood formation. In this review, we will focus on two different aspects, the lignification process and the control of microfibril angle in the cell wall of wood fibres, as they are both key features of wood material properties. Copyright (c) 2010 Académie des sciences. Published by Elsevier SAS. All rights reserved.

Developments of the EXFOR Database: Possible New Formats

DOE Office of Scientific and Technical Information (OSTI.GOV)

Forrest, R.A., E-mail: r.forrest@iaea.org; Zerkin, V.; Simakov, S.

2014-06-15

The EXFOR database is a collection of experimental nuclear reaction data, maintained by the IAEA on behalf of the International Network of Nuclear Reaction Data Centres (NRDC). The format for the storage of such data was first described in 1969 and while there have been many incremental changes over the years so that the format is now capable of containing a very wide range of measurement results, there is a growing realisation that a major change is required. Consequently the IAEA Nuclear Data Section (NDS) organised a Consultant's Meeting on ‘Further Development of EXFOR’ in 2012. This was an opportunitymore » for a range of international experts to discuss ways of improving EXFOR and while this focused on new formats there was also discussion on ways of storing new data, new output formats and software tools such as editors. This paper will discuss recent and proposed changes to enable new quantities to be stored (such as coincidence measurements and covariances), the range of output formats available (e.g. C4 and X4+) which make interaction with the data more user friendly and the possible use of XML to modernise the database.« less

Planet Formation in Binaries

NASA Astrophysics Data System (ADS)

Thebault, P.; Haghighipour, N.

Spurred by the discovery of numerous exoplanets in multiple systems, binaries have become in recent years one of the main topics in planet formation research. Numerous studies have investigated to what extent the presence of a stellar companion can affect the planet formation process. Such studies have implications that can reach beyond the sole context of binaries, as they allow to test certain aspects of the planet formation scenario by submitting them to extreme environments. We review here the current understanding on this complex problem. We show in particular how each of the different stages of the planet-formation process is affected differently by binary perturbations. We focus especially on the intermediate stage of kilometre-sized planetesimal accretion, which has proven to be the most sensitive to binarity and for which the presence of some exoplanets observed in tight binaries is difficult to explain by in-situ formation following the "standard" planet-formation scenario. Some tentative solutions to this apparent paradox are presented. The last part of our review presents a thorough description of the problem of planet habitability, for which the binary environment creates a complex situation because of the presence of two irradation sources of varying distance.

Recent progress towards a quantitative description of filamentary SOL transport

NASA Astrophysics Data System (ADS)

Carralero, D.; Siccinio, M.; Komm, M.; Artene, S. A.; D'Isa, F. A.; Adamek, J.; Aho-Mantila, L.; Birkenmeier, G.; Brix, M.; Fuchert, G.; Groth, M.; Lunt, T.; Manz, P.; Madsen, J.; Marsen, S.; Müller, H. W.; Stroth, U.; Sun, H. J.; Vianello, N.; Wischmeier, M.; Wolfrum, E.; ASDEX Upgrade Team; COMPASS Team; Contributors, JET; The EUROfusion MST Team

2017-05-01

A summary of recent results on filamentary transport, mostly obtained with the ASDEX-Upgrade tokamak (AUG), is presented and discussed in an attempt to produce a coherent picture of scrape-off layer (SOL) filamentary transport. A clear correlation is found between L-mode density shoulder formation in the outer midplane and a transition between the sheath-limited and the inertial filamentary regimes. Divertor collisionality is found to be the parameter triggering the transition. A clear reduction of the ion temperature takes place in the far SOL after the transition, both for the background and the filaments. This coincides with a strong variation of the ion temperature distribution, which deviates from Gaussianity and becomes dominated by a strong peak below 5 eV. The filament transition mechanism triggered by a critical value of collisionality seems to be generally applicable to inter-ELM H-mode plasmas, although a secondary threshold related to deuterium fueling is observed. EMC3-EIRENE simulations of neutral dynamics show that an ionization front near the main chamber wall is formed after the shoulder formation. Finally, a clear increase of SOL opacity to neutrals is observed, associated with the shoulder formation. A common SOL transport framework is proposed to account for all these results, and their potential implications for future generation devices are discussed.

Recent Results on T and CP Violation at BABAR

DOE Office of Scientific and Technical Information (OSTI.GOV)

Perez Perez, Alejandro

2015-02-06

CP-violation (CPV) and Time-reversal violation (TRV) are intimately related through the CPT theorem: if one of these discrete symmetries is violated the other one has to be violated in such a way to conserve CPT. Although CPV in the B 0B 0-bar system has been established by the B-factories, implying indirectly TRV, there is still no direct evidence of TRV. We report on the observation of TRV in the B-meson system performed with a dataset of 468 × 10 6 BB-bar pairs produced in Υ(4S) decays collected by the BABAR detector at the PEP-II asymmetric-energy e +e - collider atmore » the SLAC National Accelerator Laboratory. We also report on other CPV measurements recently performed on the B-meson system« less

Spatial variation of stratospheric aerosol acidity and model refractive index - Implications of recent results

NASA Technical Reports Server (NTRS)

Russell, P. B.; Hamill, P.

1984-01-01

Recent experimental results indicate that little or no solid ammonium sulfate is present in background stratospheric aerosols. Other results allow straightforward calculation of sulfuric acid/water droplet properties (acidity, specific gravity, refractive index) as functions of stratospheric temperature and humidity. These results are combined with a variety of latitudinal and seasonal temperature and humidity profiles to obtain corresponding profiles of droplet properties. These profiles are used to update a previous model of stratospheric aerosol refractive index. The new model retains the simplifying approximation of vertically constant refractive index in the inner stratosphere, but has sulfuric acid/water refractive index values that significantly exceed the previously used room temperature values. Mean conversion ratios (e.g., extinction-to-number, backscatter-to-volume) obtained using Mie scattering calculations with the new refractive indices are very similar to those obtained for the old indices, because the effects of deleting ammonium sulfate and increasing acid indices tend to cancel each other.

Some recent multi-frequency electron paramagnetic resonance results on systems relevant for dosimetry and dating.

PubMed

Callens, F; Vanhaelewyn, G; Matthys, P

2002-04-01

Electron Paramagnetic Resonance (EPR) applications like e.g. EPR dosimetry and dating, are usually performed at X-band frequencies because of practical reasons (cost, sample size, etc.). However, it is increasingly recognized that the radiation-induced EPR signals are strongly composite, what might affect dose/age estimates. A few recent examples from both the dosimetry and dating field, illustrating the problems, will be presented. The involved spectra are mainly due to carbonate-derived radicals (CO2-, CO3(3-), etc.). Measurements at higher microwave frequencies are often recommended to improve the insight into the spectra and/or the practical signal quantification. Recent results at Q- and W-band frequencies will show that a multi-frequency approach indeed opens many interesting perspectives in this field but also that each frequency may have specific (dis)advantages depending on the EPR probe and application involved. The discussion will concern carbonate-containing apatite single crystals, shells, modern and fossil tooth enamel.

Galaxy collisions as a mechanism of ultra diffuse galaxy (UDG) formation

NASA Astrophysics Data System (ADS)

Baushev, A. N.

2018-04-01

We suggest a possible mechanism of ultra diffuse galaxy formation: the UDGs may occur as a result of a central collision of galaxies. If the galaxies are young and contain a lot of gas, the collision may kick all the gas off the systems and thus strongly suppress any further star formation. As a result, the galaxies now have a very low surface brightness and other properties typical of the ultra diffuse galaxies. We use the Coma cluster (where numerous UDGs were recently discovered) to test the efficiency of the process. The mechanism works very well and can transform a significant fraction of the cluster population into ultra diffuse galaxies. The UDGs formed by the process concentrate towards the center of the cluster, and their globular cluster systems remain undamaged, in accordance with observational results. The projected surface density of UDGs in the cluster may help us to recognize the mechanism of UDG formation, or clarify relative contributions of several possible competitive mechanisms at work.

Video scrambling for privacy protection in video surveillance: recent results and validation framework

NASA Astrophysics Data System (ADS)

Dufaux, Frederic

2011-06-01

The issue of privacy in video surveillance has drawn a lot of interest lately. However, thorough performance analysis and validation is still lacking, especially regarding the fulfillment of privacy-related requirements. In this paper, we first review recent Privacy Enabling Technologies (PET). Next, we discuss pertinent evaluation criteria for effective privacy protection. We then put forward a framework to assess the capacity of PET solutions to hide distinguishing facial information and to conceal identity. We conduct comprehensive and rigorous experiments to evaluate the performance of face recognition algorithms applied to images altered by PET. Results show the ineffectiveness of naïve PET such as pixelization and blur. Conversely, they demonstrate the effectiveness of more sophisticated scrambling techniques to foil face recognition.

Star formation in the cluster merger DLSCL J0916.2+2953

DOE PAGES

Mansheim, A. S.; Lemaux, B. C.; Dawson, W. A.; ...

2017-01-13

We investigate star formation in DLSCL J0916.2+2953, a dissociative merger of two clusters at z=0.53 that has progressed 1:1 +1.3 -0.4 Gyr since rst pass-through. We attempt to reveal the effects a collision may have had on the evolution of the cluster galaxies by tracing their star formation history. We probe current and recent activity to identify a possible star formation event at the time of the merger using EW(Hδ), EW([OII]), and Dn(4000) measured from the composite spectra of 64 cluster and 153 coeval eld galaxies. We supplement Keck DEIMOS spectra with DLS and HST imaging to determine the color,more » stellar mass, and morphology of each galaxy and conduct a comprehensive study of the populations in this complex structure. Spectral results indicate the average cluster and cluster red sequence galaxies experienced no enhanced star formation relative to the surrounding eld during the merger, ruling out a predominantly merger-quenched population. We nd that the average blue galaxy in the North cluster is currently active and in the South cluster is currently post-starburst having undergone a recent star formation event. While the North activity could be latent or long- term merger effects, a young blue stellar population and irregular geometry suggest the cluster was still forming prior the collision. While the South activity coincides with the time of the merger, the blue early-type population could be a result of secular cluster processes. The evidence suggests that the dearth or surfeit of activity is indiscernible from normal cluster galaxy evolution.« less

Nucleation in mesoscopic systems under transient conditions: Peptide-induced pore formation in vesicles

NASA Astrophysics Data System (ADS)

Zhdanov, Vladimir P.; Höök, Fredrik

2013-04-01

Attachment of lytic peptides to the lipid membrane of virions or bacteria is often accompanied by their aggregation and pore formation, resulting eventually in membrane rupture and pathogen neutralization. The membrane rupture may occur gradually via formation of many pores or abruptly after the formation of the first pore. In academic studies, this process is observed during interaction of peptides with lipid vesicles. We present an analytical model and the corresponding Monte Carlo simulations focused on the pore formation in such situations. Specifically, we calculate the time of the first nucleation-limited pore-formation event and show the distribution of this time in the regime when the fluctuations of the number of peptides attached to a vesicle are appreciable. The results obtained are used to clarify the mechanism of the pore formation and membrane destabilization observed recently during interaction of highly active α-helical peptide with sub-100-nm lipid vesicles that mimic enveloped viruses with nanoscale membrane curvature. The model proposed and the analysis presented are generic and may be applicable to other meso- and nanosystems.

High-spin studies: Recent results from the 8π spectrometer

NASA Astrophysics Data System (ADS)

Radford, D. C.; Galindo-Uribarri, A.; Hackman, G.; Janzen, V. P.; 8π Collaboration

1993-05-01

Selected highlights of recent high-spin nuclear-structure studies with the 8π spectrometer are presented. These include an extensive systematic study of high- j intruder bands in A ˜ 110 Sb, Sn and In nuclei; evidence for hyperdeformation, observed in the reaction 120Sn( 37Cl,px n) populating 152,153Dy; and the observation of a new superdeformed band in the N = 80 nucleus 142Sm. The design of "TRIGAM", a new HPGe-detector array proposed to replace the 8π spectrometer, is also presented.

Recent advances in plant centromere biology.

PubMed

Feng, Chao; Liu, YaLin; Su, HanDong; Wang, HeFei; Birchler, James; Han, FangPu

2015-03-01

The centromere, which is one of the essential parts of a chromosome, controls kinetochore formation and chromosome segregation during mitosis and meiosis. While centromere function is conserved in eukaryotes, the centromeric DNA sequences evolve rapidly and have few similarities among species. The histone H3 variant CENH3 (CENP-A in human), which mostly exists in centromeric nucleosomes, is a universal active centromere mark in eukaryotes and plays an essential role in centromere identity determination. The relationship between centromeric DNA sequences and centromere identity determination is one of the intriguing questions in studying centromere formation. Due to the discoveries in the past decades, including "neocentromeres" and "centromere inactivation", it is now believed that the centromere identity is determined by epigenetic mechanisms. This review will present recent progress in plant centromere biology.

Recent results from PHOBOS at RHIC

NASA Astrophysics Data System (ADS)

Back, B. B.; Baker, M. D.; Barton, D. S.; Betts, R. R.; Ballintijn, M.; Bickley, A. A.; Bindel, R.; Budzanowski, A.; Busza, W.; Carroll, A.; Decowski, M. P.; García, E.; George, N.; Gulbrandsen, K.; Gushue, S.; Halliwell, C.; Hamblen, J.; Heintzelman, G. A.; Henderson, C.; Hofman, D. J.; Hollis, R. S.; Hołyński, R.; Holzman, B.; Iordanova, A.; Johnson, E.; Kane, J. L.; Katzy, J.; Khan, N.; Kucewicz, W.; Kulinich, P.; Kuo, C. M.; Lin, W. T.; Manly, S.; McLeod, D.; Michałowski, J.; Mignerey, A. C.; Nouicer, R.; Olszewski, A.; Pak, R.; Park, I. C.; Pernegger, H.; Reed, C.; Remsberg, L. P.; Reuter, M.; Roland, C.; Roland, G.; Rosenberg, L.; Sagerer, J.; Sarin, P.; Sawicki, P.; Skulski, W.; Steadman, S. G.; Steinberg, P.; Stephans, G. S. F.; Stodulski, M.; Sukhanov, A.; Tang, J.-L.; Teng, R.; Trzupek, A.; Vale, C.; van Niewwenhuizen, G. J.; Verdier, R.; Wadsworth, B.; Wolfs, F. L. H.; Wosiek, B.; Woźniak, K.; Wuosmaa, A. H.; Wysłouch, B.; Robert PakThe Phobos Collaboration

2003-06-01

The PHOBOS experiment at RHIC has recorded measurements for AuAu collisions spanning nucleon-nucleon center-of-mass energies from √ SNN = 19.6 GeV to 200 GeV. Global observables such as elliptic flow and charged particle multiplicity provide important constraints on model predictions that characterize the state of matter produced in these collisions. The nearly 4π acceptance of the PHOBOS experiment provides excellent coverage for complete flow and multiplicity measurements. Results including beam energy and centrality dependencies are presented and compared to elementary systems.

Numerical Simulation of the Global Star Formation Pattern in the LMC

NASA Astrophysics Data System (ADS)

Gardiner, L. T.; Turfus, C.

Dottori et al. (1996, ApJ 461, 742) have recently presented evidence for the idea that the observed distribution of young star clusters in the Large Magellanic Cloud (LMC) has resulted from the gravitational perturbation induced by a bar potential offset from the LMC disk center. We have constructed a dynamical model of the LMC to examine the effects of such an off-center perturbation on the global distribution of the gas and star formation activity. We have used a newly developed hybrid N-body/cellular automaton scheme for modeling star formation in galaxies which incorporates the dual mechanisms of gravitational instability and self-propagating star formation, combined with feedback of kinetic energy from star-forming regions into the interstellar medium. We find that a weak rotating bar perturbation, whose center is displaced by 0.6 kpc from the disk center, gives rise to an asymmetric spiral structure which mimics the chains of recent star formation observed in the LMC as well as delineating activity in the bar region. Large gas concentrations are produced where the spiral arms merge in the northern part of the galaxy, and such structures may have observed counterparts in giant star-forming complexes such as Constellation III in the NE part of the LMC.

Theoretical Studies of Dust in the Galactic Environment: Some Recent Advances

NASA Technical Reports Server (NTRS)

Leung, Chun Ming

1995-01-01

Dust grains, although a minor constituent, play a very important role in the thermodynamics and evolution of many astronomical objects, e.g., young and evolved stars, nebulae, interstellar clouds, and nuclei of some galaxies. Since the birth of infrared astronomy over two decades ago, significant progress has been made not only in the observations of galactic dust, but also in the theoretical studies of phenomena involving dust grains. Models with increasing degree of sophistication and physical realism (in terms of grain properties, dust formation, emission processes, and grain alignment mechanisms) have become available. Here I review recent progress made in the following areas: (1) Extinction and emission of fractal grains. (2) Dust formation in radiation-driven outflows of evolved stars. (3) Transient heating and emission of very small dust grains. Where appropriate, relevant modeling results are presented and observational implications emphasized.

Identifying the Role of Common Interests in Online User Trust Formation

PubMed Central

Ji, Lei; Liu, Jian-Guo; Hou, Lei; Guo, Qiang

2015-01-01

Despite enormous recent efforts in detecting the mechanism of the social relation formation in online social systems, the underlying rules between the common interests and social relations are still under dispute. Do online users befriend others who have similar tastes, or do their tastes become more similar after they become friends? In this paper, we investigate the correlation between online user trust formation and their common interests, measured by the overlap rate ρ and taste similarity θ respectively. The trust relation creation time is set as the zero timestamp. The statistical results before and after the trust formation for an online network, namely Epinions, show that, the overlap rate ρ increases greatly before the trust formation, while it would increase smoothly after the creation of the trust relation. Comparing with the empirical results, two null models are presented by shuffling the temporal behaviors of online users, which suggests that the accumulation of the common interests can result in the trust formation. Furthermore, we investigate the taste similarity θ of the common interests, which can reflect the users’ preference on their common interests. The empirical results show that the taste similarity θ is rapidly increased around the day when users trust the others. That is, the similar tastes on the common interests among users lead to the trust formation. Finally, we report that the user degree can also influence the effect of the taste similarity θ on user trust formation. This work may shed some light for deeply understanding the evolution mechanism of the online social systems. PMID:26161853

Identifying the Role of Common Interests in Online User Trust Formation.

PubMed

Ji, Lei; Liu, Jian-Guo; Hou, Lei; Guo, Qiang

2015-01-01

Despite enormous recent efforts in detecting the mechanism of the social relation formation in online social systems, the underlying rules between the common interests and social relations are still under dispute. Do online users befriend others who have similar tastes, or do their tastes become more similar after they become friends? In this paper, we investigate the correlation between online user trust formation and their common interests, measured by the overlap rate ρ and taste similarity θ respectively. The trust relation creation time is set as the zero timestamp. The statistical results before and after the trust formation for an online network, namely Epinions, show that, the overlap rate ρ increases greatly before the trust formation, while it would increase smoothly after the creation of the trust relation. Comparing with the empirical results, two null models are presented by shuffling the temporal behaviors of online users, which suggests that the accumulation of the common interests can result in the trust formation. Furthermore, we investigate the taste similarity θ of the common interests, which can reflect the users' preference on their common interests. The empirical results show that the taste similarity θ is rapidly increased around the day when users trust the others. That is, the similar tastes on the common interests among users lead to the trust formation. Finally, we report that the user degree can also influence the effect of the taste similarity θ on user trust formation. This work may shed some light for deeply understanding the evolution mechanism of the online social systems.

Shock Formation Height in the Solar Corona Estimated from SDO and Radio Observations

NASA Technical Reports Server (NTRS)

Gopalswamy, N.; Nitta, N.

2011-01-01

Wave transients at EUV wavelengths and type II radio bursts are good indicators of shock formation in the solar corona. We use recent EUV wave observations from SDO and combine them with metric type II radio data to estimate the height in the corona where the shocks form. We compare the results with those obtained from other methods. We also estimate the shock formation heights independently using white-light observations of coronal mass ejections that ultimately drive the shocks.

Recent progress in flexible OLED displays

NASA Astrophysics Data System (ADS)

Hack, Michael G.; Weaver, Michael S.; Mahon, Janice K.; Brown, Julie J.

2001-09-01

Organic light emitting device (OLED) technology has recently been shown to demonstrate excellent performance and cost characteristics for use in numerous flat panel display (FPD) applications. OLED displays emit bright, colorful light with excellent power efficiency, wide viewing angle and video response rates. OLEDs are also demonstrating the requisite environmental robustness for a wide variety of applications. OLED technology is also the first FPD technology with the potential to be highly functional and durable in a flexible format. The use of plastic and other flexible substrate materials offers numerous advantages over commonly used glass substrates, including impact resistance, light weight, thinness and conformability. Currently, OLED displays are being fabricated on rigid substrates, such as glass or silicon wafers. At Universal Display Corporation (UDC), we are developing a new class of flexible OLED displays (FOLEDs). These displays also have extremely low power consumption through the use of electrophosphorescent doped OLEDs. To commercialize FOLED technology, a number of technical issues related to packaging and display processing on flexible substrates need to be addressed. In this paper, we report on our recent results to demonstrate the key technologies that enable the manufacture of power efficient, long-life flexible OLED displays for commercial and military applications.

Enhanced BMP signaling results in supernumerary tooth formation in USAG-1 deficient mouse

DOE Office of Scientific and Technical Information (OSTI.GOV)

Murashima-Suginami, Akiko; Takahashi, Katsu; Sakata, Tomoko

2008-05-16

Uterine sensitization associated gene-1 (USAG-1) is a BMP antagonist, and also modulates Wnt signaling. We previously reported that USAG-1 deficient mice have supernumerary teeth. The supernumerary maxillary incisor appears to form as a result of the successive development of the rudimentary upper incisor. USAG-1 abrogation rescued apoptotic elimination of odontogenic mesenchymal cells. We confirmed that BMPs were expressed in both the epithelium and mesenchyme of the rudimentary incisor at E14 and E15. BMP signaling in the rudimentary maxillary incisor, assessed by expressions of Msx1 and Dlx2 and the phosphorylation of Smad protein, was significantly enhanced. Wnt signaling as demonstrated bymore » the nuclear localization of {beta}-catenin was also up-regulated. Inhibition of BMP signaling rescues supernumerary tooth formation in E15 incisor explant culture. Based upon these results, we conclude that enhanced BMP signaling results in supernumerary teeth and BMP signaling was modulated by Wnt signaling in the USAG-1 deficient mouse model.« less

Progress and Challenges in SPH Simulations of Disk Galaxy Formation: The Combined Role of Resolution and the Star Formation Density Threshold

NASA Astrophysics Data System (ADS)

Mayer, L.

2012-07-01

We review progress in cosmological SPH simulations of disk galaxy formation. We discuss the role of numerical resolution and sub-grid recipes of star formation and feedback from supernovae, higlighting the important role of a high star formation density threshold comparable to that of star forming molecular gas phase. Two recent succesfull examples, in simulations of the formation of gas-rich bulgeless dwarf galaxies and in simulations of late-type spirals (the ERIS simulations), are presented and discussed. In the ERIS simulations, already in the progenitors at z = 3 the resolution is above the threshold indicated by previous idealized numerical experiments as necessary to minimize numerical angular momentum loss (Kaufmann et al. 2007). A high star formation density threshold maintains an inhomogeneous interstellar medium, where star formation is clustered, and thus the local effect of supernovae feedback is enhanced. As a result, outflows are naturally generated removing 2/3 of the baryons in galaxies with Vvir˜50 km/s and ˜ 30% of the baryons in galaxies with (Vvir ˜ 150 km/s). Low angular momentum baryons are preferentially removed since the strongest bursts of star formation occur predominantly near the center, especially after a merger event. This produces pure exponential disks or small bulges depending on galaxy mass, and, correspondingly, slowly rising or nearly flat rotation curves that match those of observed disk galaxies. In dwarfs the rapid mass removal by outflows generates a core-like distribution in the dark matter. Furthermore, contrary to the common picture, in the ERIS spiral galaxies a bar/pseudobulge forms rapidly, and not secularly, as a result of mergers and interactions at high-z.

Macrophage conditioned medium induced cellular network formation in MCF-7 cells through enhanced tunneling nanotube formation and tunneling nanotube mediated release of viable cytoplasmic fragments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Patheja, Pooja, E-mail: pooja.patheja8@gmail.com; Homi Bhabha National Institute, Training School Complex, Anushaktinagar, Mumbai 400094, Maharashtra; Sahu, Khageswar

Infiltrating macrophages in tumor microenvironment, through their secreted cytokines and growth factors, regulate several processes of cancer progression such as cancer cell survival, proliferation, invasion, metastasis and angiogenesis. Recently, intercellular cytoplasmic bridges between cancer cells referred as tunneling nanotubes (TNTs) have been recognized as novel mode of intercellular communication between cancer cells. In this study, we investigated the effect of inflammatory mediators present in conditioned medium derived from macrophages on the formation of TNTs in breast adenocarcinoma cells MCF-7. Results show that treatment with macrophage conditioned medium (MφCM) not only enhanced TNT formation between cells but also stimulated the releasemore » of independently migrating viable cytoplasmic fragments, referred to as microplasts, from MCF-7 cells. Time lapse microscopy revealed that microplasts were released from parent cancer cells in extracellular space through formation of TNT-like structures. Mitochondria, vesicles and cytoplasm could be transferred from parent cell body to microplasts through connecting TNTs. The microplasts could also be resorbed into the parent cell body by retraction of the connecting TNTs. Microplast formation inhibited in presence cell migration inhibitor, cytochalasin-B. Notably by utilizing migratory machinery within microplasts, distantly located MCF-7 cells formed several TNT based intercellular connections, leading to formation of physically connected network of cells. Together, these results demonstrate novel role of TNTs in microplast formation, novel modes of TNT formation mediated by microplasts and stimulatory effect of MφCM on cellular network formation in MCF-7 cells mediated through enhanced TNT and microplast formation.« less

Macrophage conditioned medium induced cellular network formation in MCF-7 cells through enhanced tunneling nanotube formation and tunneling nanotube mediated release of viable cytoplasmic fragments.

PubMed

Patheja, Pooja; Sahu, Khageswar

2017-06-15

Infiltrating macrophages in tumor microenvironment, through their secreted cytokines and growth factors, regulate several processes of cancer progression such as cancer cell survival, proliferation, invasion, metastasis and angiogenesis. Recently, intercellular cytoplasmic bridges between cancer cells referred as tunneling nanotubes (TNTs) have been recognized as novel mode of intercellular communication between cancer cells. In this study, we investigated the effect of inflammatory mediators present in conditioned medium derived from macrophages on the formation of TNTs in breast adenocarcinoma cells MCF-7. Results show that treatment with macrophage conditioned medium (MɸCM) not only enhanced TNT formation between cells but also stimulated the release of independently migrating viable cytoplasmic fragments, referred to as microplasts, from MCF-7 cells. Time lapse microscopy revealed that microplasts were released from parent cancer cells in extracellular space through formation of TNT-like structures. Mitochondria, vesicles and cytoplasm could be transferred from parent cell body to microplasts through connecting TNTs. The microplasts could also be resorbed into the parent cell body by retraction of the connecting TNTs. Microplast formation inhibited in presence cell migration inhibitor, cytochalasin-B. Notably by utilizing migratory machinery within microplasts, distantly located MCF-7 cells formed several TNT based intercellular connections, leading to formation of physically connected network of cells. Together, these results demonstrate novel role of TNTs in microplast formation, novel modes of TNT formation mediated by microplasts and stimulatory effect of MɸCM on cellular network formation in MCF-7 cells mediated through enhanced TNT and microplast formation. Copyright © 2017 Elsevier Inc. All rights reserved.

Combating atherosclerosis with targeted nanomedicines: recent advances and future prospective

PubMed Central

Nakhlband, Ailar; Eskandani, Morteza; Saeedi, Nazli; Ghaffari, Samad; Garjani, Alireza

2018-01-01

Introduction: Cardiovascular diseases (CVDs) is recognized as the leading cause of mortality worldwide. The increasing prevalence of such disease demands novel therapeutic and diagnostic approaches to overcome associated clinical/social issues. Recent advances in nanotechnology and biological sciences have provided intriguing insights to employ targeted Nanomachines to the desired location as imaging, diagnosis, and therapeutic modalities. Nanomedicines as novel tools for enhanced drug delivery, imaging, and diagnosis strategies have shown great promise to combat cardiovascular diseases. Methods: In the current study, we intend to review the most recent studies on the nano-based strategies for improved management of CVDs. Results: A cascade of events results in the formation of atheromatous plaque and arterial stenosis. Furthermore, recent studies have shown that nanomedicines have displayed unique functionalities and provided de novo applications in the diagnosis and treatment of atherosclerosis. Conclusion: Despite some limitations, nanomedicines hold considerable potential in the prevention, diagnosis, and treatment of various ailments including atherosclerosis. Fewer side effects, amenable physicochemical properties and multi-potential application of such nano-systems are recognized through various investigations. Therefore, it is strongly believed that with targeted drug delivery to atherosclerotic lesions and plaque, management of onset and progression of disease would be more efficient than classical treatment modalities. PMID:29713603

Clues to the Formation of Lenticular Galaxies Using Spectroscopic Bulge-Disk Decomposition

NASA Astrophysics Data System (ADS)

Johnston, E. J.; Aragón-Salamanca, A.; Merrifield, M. R.; Bedregal, A. G.

2014-03-01

Lenticular galaxies have long been thought of as evolved spirals, but the processes involved to quench the star formation are still unclear. By studying the individual star formation histories of the bulges and disks of lenticulars, it is possible to look for clues to the processes that triggered their transformation from spirals. To accomplish this feat, we present a new method for spectroscopic bulge-disk decomposition, in which a long-slit spectrum is decomposed into two one-dimensional spectra representing purely the bulge and disk light. We present preliminary results from applying this method to lenticular galaxies in the Virgo and Fornax Clusters, in which we show that the most recent star formation activity in these galaxies occurred within the bulges. We also find that the star formation timescales of the bulges are longer than the disks, and that more massive galaxies take longer to lose their gas during the transformation. These results point towards slow processes, such as ram-pressure stripping or harassment, being the mechanism responsible for the quenching of star formation in spirals, followed by a burst of star formation in the central regions from the gas that has been funnelled inwards through the disk.

First Results from the Dense Extragalactic GBT+ARGUS Survey (DEGAS): A Direct, Quantitative Test of the Role of Gas Density in Star Formation

NASA Astrophysics Data System (ADS)

Kepley, Amanda; Bigiel, Frank; Bolatto, Alberto; Church, Sarah; Cleary, Kieran; Frayer, David; Gallagher, Molly; Gundersen, Joshua; Harris, Andrew; Hughes, Annie; Jimenez-Donaire, Maria Jesus; Kessler, Sarah; Lee, Cheoljong; Leroy, Adam; Li, Jialu; Donovan Meyer, Jennifer; Rosolowsky, Erik; Sandstrom, Karin; Schinnener, Eva; Schruba, Andreas; Sieth, Matt; Usero, Antonio

2018-01-01

Gas density plays a central role in all modern theories of star formation. A key test of these theories involves quantifying the resolved gas density distribution and its relationship to star formation within a wide range of galactic environments. Until recently, this experiment has been difficult to perform owing to the faint nature of key molecular gas tracers like HCN and HCO+, but the superior sensitivity of modern millimeter instruments like ALMA and the IRAM 30m make these types of experiments feasible. In particular, the sensitivity and resolution provided by large aperture of the GBT combined with fast mapping speeds made possible by its new 16-pixel, 3mm focal plane array (Argus) make the GBT an almost-ideal instrument for this type of study. The Dense Extragalactic GBT+Argus Survey (DEGAS) will leverage these capabilities to perform the largest, resolved survey of molecular gas tracers in nearby galaxies, ultimately mapping a suite of four molecular gas tracers in the inner 2’ by 2’ of 36 nearby galaxies. When complete in 2020, DEGAS will be the largest resolved survey of dense molecular gas tracers in nearby galaxies. This talk will present early results from the first observations for this Green Bank Telescope large survey and highlight some exciting future possibilities for this survey.

Hydrogen or formate: Alternative key players in methanogenic degradation.

PubMed

Schink, Bernhard; Montag, Dominik; Keller, Anja; Müller, Nicolai

2017-06-01

Hydrogen and formate are important electron carriers in methanogenic degradation in anoxic environments such as sediments, sewage sludge digestors and biogas reactors. Especially in the terminal steps of methanogenesis, they determine the energy budgets of secondary (syntrophically) fermenting bacteria and their methanogenic partners. The literature provides considerable data on hydrogen pool sizes in such habitats, but little data exist for formate concentrations due to technical difficulties in formate determination at low concentration. Recent evidence from biochemical and molecular biological studies indicates that several secondary fermenters can use both hydrogen and formate for electron release, and may do so even simultaneously. Numerous strictly anaerobic bacteria contain enzymes which equilibrate hydrogen and formate pools to energetically equal values, and recent measurements in sewage digestors and biogas reactors indicate that - beyond occasional fluctuations - the pool sizes of hydrogen and formate are indeed energetically nearly equivalent. Nonetheless, a thermophilic archaeon from a submarine hydrothermal vent, Thermococcus onnurineus, can obtain ATP from the conversion of formate to hydrogen plus bicarbonate at 80°C, indicating that at least in this extreme environment the pools of formate and hydrogen are likely to be sufficiently different to support such an unusual type of energy conservation. © 2017 Society for Applied Microbiology and John Wiley & Sons Ltd.

A comparison of the rates of hydrocarbon generation from Lodgepole, False Bakken, and Bakken formation petroleum source rocks, Williston Basin, USA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jarvie, D.M.; Elsinger, R.J.; Inden, R.F.

1996-06-01

Recent successes in the Lodgepole Waulsortian Mound play have resulted in the reevaluation of the Williston Basin petroleum systems. It has been postulated that hydrocarbons were generated from organic-rich Bakken Formation source rocks in the Williston Basin. However, Canadian geoscientists have indicated that the Lodgepole Formation is responsible for oil entrapped in Lodgepole Formation and other Madison traps in portions of the Canadian Williston Basin. Furthermore, geoscientists in the U.S. have recently shown oils from mid-Madison conventional reservoirs in the U.S. Williston Basin were not derived from Bakken Formation source rocks. Kinetic data showing the rate of hydrocarbon formation frommore » petroleum source rocks were measured on source rocks from the Lodgepole, False Bakken, and Bakken Formations. These results show a wide range of values in the rate of hydrocarbon generation. Oil prone facies within the Lodgepole Formation tend to generate hydrocarbons earlier than the oil prone facies in the Bakken Formation and mixed oil/gas prone and gas prone facies in the Lodgepole Formation. A comparison of these source rocks using a geological model of hydrocarbon generation reveals differences in the timing of generation and the required level of maturity to generate significant amounts of hydrocarbons.« less

Galaxy Zoo: evidence for rapid, recent quenching within a population of AGN host galaxies

NASA Astrophysics Data System (ADS)

Smethurst, R. J.; Lintott, C. J.; Simmons, B. D.; Schawinski, K.; Bamford, S. P.; Cardamone, C. N.; Kruk, S. J.; Masters, K. L.; Urry, C. M.; Willett, K. W.; Wong, O. I.

2016-12-01

We present a population study of the star formation history of 1244 Type 2 active galactic nuclei (AGN) host galaxies, compared to 6107 inactive galaxies. A Bayesian method is used to determine individual galaxy star formation histories, which are then collated to visualize the distribution for quenching and quenched galaxies within each population. We find evidence for some of the Type 2 AGN host galaxies having undergone a rapid drop in their star formation rate within the last 2 Gyr. AGN feedback is therefore important at least for this population of galaxies. This result is not seen for the quenching and quenched inactive galaxies whose star formation histories are dominated by the effects of downsizing at earlier epochs, a secondary effect for the AGN host galaxies. We show that histories of rapid quenching cannot account fully for the quenching of all the star formation in a galaxy's lifetime across the population of quenched AGN host galaxies, and that histories of slower quenching, attributed to secular (non-violent) evolution, are also key in their evolution. This is in agreement with recent results showing that both merger-driven and non-merger processes are contributing to the co-evolution of galaxies and supermassive black holes. The availability of gas in the reservoirs of a galaxy, and its ability to be replenished, appear to be the key drivers behind this co-evolution.

Recent Advances in the GLIMS Glacier Database

NASA Astrophysics Data System (ADS)

Raup, Bruce; Cogley, Graham; Zemp, Michael; Glaus, Ladina

2017-04-01

Glaciers are shrinking almost without exception. Glacier losses have impacts on local water availability and hazards, and contribute to sea level rise. To understand these impacts and the processes behind them, it is crucial to monitor glaciers through time by mapping their areal extent, changes in volume, elevation distribution, snow lines, ice flow velocities, and changes to associated water bodies. The glacier database of the Global Land Ice Measurements from Space (GLIMS) initiative is the only multi-temporal glacier database capable of tracking all these glacier measurements and providing them to the scientific community and broader public. Here we present recent results in 1) expansion of the geographic and temporal coverage of the GLIMS Glacier Database by drawing on the Randolph Glacier Inventory (RGI) and other new data sets; 2) improved tools for visualizing and downloading GLIMS data in a choice of formats and data models; and 3) a new data model for handling multiple glacier records through time while avoiding double-counting of glacier number or area. The result of this work is a more complete glacier data repository that shows not only the current state of glaciers on Earth, but how they have changed in recent decades. The database is useful for tracking changes in water resources, hazards, and mass budgets of the world's glaciers.

Serum albumin coating of demineralized bone matrix results in stronger new bone formation.

PubMed

Horváthy, Dénes B; Vácz, Gabriella; Szabó, Tamás; Szigyártó, Imola C; Toró, Ildikó; Vámos, Boglárka; Hornyák, István; Renner, Károly; Klára, Tamás; Szabó, Bence T; Dobó-Nagy, Csaba; Doros, Attila; Lacza, Zsombor

2016-01-01

Blood serum fractions are hotly debated adjuvants in bone replacement therapies. In the present experiment, we coated demineralized bone matrices (DBM) with serum albumin and investigated stem cell attachment in vitro and bone formation in a rat calvaria defect model. In the in vitro experiments, we observed that significantly more cells adhere to the serum albumin coated DBMs at every time point. In vivo bone formation with albumin coated and uncoated DBM was monitored biweekly by computed tomography until 11 weeks postoperatively while empty defects served as controls. By the seventh week, the bone defect in the albumin group was almost completely closed (remaining defect 3.0 ± 2.3%), while uncoated DBM and unfilled control groups still had significant defects (uncoated: 40.2 ± 9.1%, control: 52.4 ± 8.9%). Higher density values were also observed in the albumin coated DBM group. In addition, the serum albumin enhanced group showed significantly higher volume of newly formed bone in the microCT analysis and produced significantly higher breaking force and stiffness compared to the uncoated grafts (peak breaking force: uncoated: 15.7 ± 4 N, albumin 46.1 ± 11 N). In conclusion, this investigation shows that implanting serum albumin coated DBM significantly reduces healing period in nonhealing defects and results in mechanically stronger bone. These results also support the idea that serum albumin coating provides a convenient milieu for stem cell function, and a much improved bone grafting success can be achieved without the use of exogenous stem cells. © 2015 Wiley Periodicals, Inc.

Formation of the Isthmus of Panama

USGS Publications Warehouse

O'Dea, Aaron; Aguilera, Orangel; Aubry, Marie-Pierre; Berggren, William A.; Cione, Alberto L.; Coates, Anthony G.; Collins, Laurel S.; Coppard, Simon E.; Cozzuol, Mario A.; de Queiroz, Alan; Duque-Caro, Herman; Eytan, Ron I.; Farris, David W.; Gasparini, German M.; Grosmman, Ethan L.; Jackson, Jeremy B. C.; Johnson, Kenneth G.; Keigwin, Lloyd D.; Knowlton, Nancy; Leigh, Egbert G.; Leonard-Pingel, Jill S.; Lessios, Hailaos A.; Marko, Peter B.; Norris, Richard D.; Rachello-Dolmen, Paola G.; Restrepo-Moreno, Sergio A.; Soibelzon, Leopoldo; Stallard, Robert F.; Todd, Jonathan A.; Vermeiju, Geerat J.; Woodburne, Michael O.

2016-01-01

The formation of the Isthmus of Panama stands as one of the greatest natural events of the Cenozoic, driving profound biotic transformations on land and in the oceans. Some recent studies suggest that the Isthmus formed many millions of years earlier than the widely recognized age of approximately 3 million years ago (Ma), a result that if true would revolutionize our understanding of environmental, ecological, and evolutionary change across the Americas. To bring clarity to the question of when the Isthmus of Panama formed, we provide an exhaustive review and reanalysis of geological, paleontological, and molecular records. These independent lines of evidence converge upon a cohesive narrative of gradually emerging land and constricting seaways, with formation of the Isthmus of Panama sensu stricto around 2.8 Ma. The evidence used to support an older isthmus is inconclusive, and we caution against the uncritical acceptance of an isthmus before the Pliocene.

Observsational Planet Formation

NASA Astrophysics Data System (ADS)

Dong, Ruobing; Zhu, Zhaohuan; Fung, Jeffrey

2017-06-01

Planets form in gaseous protoplanetary disks surrounding newborn stars. As such, the most direct way to learn how they form from observations, is to directly watch them forming in disks. In the past, this was very difficult due to a lack of observational capabilities; as such, planet formation was largely a subject of pure theoretical astrophysics. Now, thanks to a fleet of new instruments with unprecedented resolving power that have come online recently, we have just started to unveil features in resolve images of protoplanetary disks, such as gaps and spiral arms, that are most likely associated with embedded (unseen) planets. By comparing observations with theoretical models of planet-disk interactions, the masses and orbits of these still forming planets may be constrained. Such planets may help us to directly test various planet formation models. This marks the onset of a new field — observational planet formation. I will introduce the current status of this field.

Aqueous ionic liquids and their effects on protein structures: an overview on recent theoretical and experimental results

NASA Astrophysics Data System (ADS)

Smiatek, Jens

2017-06-01

Ionic liquids (ILs) are used in a variety of technological and biological applications. Recent experimental and simulation results reveal the influence of aqueous ionic liquids on the stability of protein and enzyme structures. Depending on different parameters like the concentration and the ion composition, one can observe distinct stabilization or denaturation mechanisms for various ILs. In this review, we summarize the main findings and discuss the implications with regard to molecular theories of solutions and specific ion effects. A preferential binding model is introduced in order to discuss protein-IL effects from a statistical mechanics perspective. The value of the preferential binding coefficient determines the strength of the ion influence and indicates a shift of the chemical equilibrium either to the native or the denatured state of the protein. We highlight the role of water in order to explain the self-association behavior of the IL species and discuss recent experimental and simulation results in the light of the observed binding effects.

The structure and evolution of galacto-detonation waves - Some analytic results in sequential star formation models of spiral galaxies

NASA Technical Reports Server (NTRS)

Cowie, L. L.; Rybicki, G. B.

1982-01-01

Waves of star formation in a uniform, differentially rotating disk galaxy are treated analytically as a propagating detonation wave front. It is shown, that if single solitary waves could be excited, they would evolve asymptotically to one of two stable spiral forms, each of which rotates with a fixed pattern speed. Simple numerical solutions confirm these results. However, the pattern of waves that develop naturally from an initially localized disturbance is more complex and dies out within a few rotation periods. These results suggest a conclusive observational test for deciding whether sequential star formation is an important determinant of spiral structure in some class of galaxies.

Entropy of balance - some recent results

PubMed Central

2010-01-01

Background Entropy when applied to biological signals is expected to reflect the state of the biological system. However the physiological interpretation of the entropy is not always straightforward. When should high entropy be interpreted as a healthy sign, and when as marker of deteriorating health? We address this question for the particular case of human standing balance and the Center of Pressure data. Methods We have measured and analyzed balance data of 136 participants (young, n = 45; elderly, n = 91) comprising in all 1085 trials, and calculated the Sample Entropy (SampEn) for medio-lateral (M/L) and anterior-posterior (A/P) Center of Pressure (COP) together with the Hurst self-similariy (ss) exponent α using Detrended Fluctuation Analysis (DFA). The COP was measured with a force plate in eight 30 seconds trials with eyes closed, eyes open, foam, self-perturbation and nudge conditions. Results 1) There is a significant difference in SampEn for the A/P-direction between the elderly and the younger groups Old > young. 2) For the elderly we have in general A/P > M/L. 3) For the younger group there was no significant A/P-M/L difference with the exception for the nudge trials where we had the reverse situation, A/P < M/L. 4) For the elderly we have, Eyes Closed > Eyes Open. 5) In case of the Hurst ss-exponent we have for the elderly, M/L > A/P. Conclusions These results seem to be require some modifications of the more or less established attention-constraint interpretation of entropy. This holds that higher entropy correlates with a more automatic and a less constrained mode of balance control, and that a higher entropy reflects, in this sense, a more efficient balancing. PMID:20670457

Handbook of Formative Assessment

ERIC Educational Resources Information Center

Andrade, Heidi, Ed.; Cizek, Gregory J., Ed.

2010-01-01

Formative assessment has recently become a focus of renewed research as state and federal policy-makers realize that summative assessments have reached a point of diminishing returns as a tool for increasing student achievement. Consequently, supporters of large-scale testing programs are now beginning to consider the potential of formative…

Recent results from the OPERA experiment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meregaglia, Anselmo

2009-04-17

OPERA is a long-baseline neutrino oscillation experiment whose main goal is to detect for the first time neutrino oscillations in an appearance mode. Using an almost pure v{sub {mu}} beam we search for a v{sub {mu}}{r_reversible}v{sub {tau}}, transition detecting in a direct way the {tau} lepton. The detector is located on the high-energy, long-baseline CERN to LNGS beam (CNGS) at a baseline of 730 km. The apparatus consists of a target made of lead/emulsion-films bricks and of electronic detectors which are used to tag the neutrino interaction. Experiment description and results from the short but fruitful 2007 CNGS run aremore » reported in details.« less

The EPRDATA Format: A Dialogue

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hughes, III, Henry Grady

2015-08-18

Recently the Los Alamos Nuclear Data Team has communicated certain issues of concern in relation to the new electron/photon/relaxation ACE data format as released in the eprdata12 library. In this document those issues are parsed, analyzed, and answered.

Recent results from the Telescope Array Experiment

NASA Astrophysics Data System (ADS)

Abbasi, Rasha; Telescope Array Collaboration

2016-03-01

The Telescope Array (TA) is the largest ultrahigh energy cosmic rays detector in the northern hemisphere. TA is a hybrid detector comprised of three air fluorescence stations and a large surface array consisting of 507 scintillator counters. Each of the three fluorescence stations, located at the periphery of the ground array, views 108 degrees in azimuth and up to 30 degrees in elevation. The surface detectors are arranged in a square grid of 1.2 km spacing, covering over 700 square kilometers. TA has collected more than seven years of data. In this talk, we will present some of the main results on the cosmic rays composition and energy spectrum obtained by TA and its low energy extension (TALE). Finally, we will present our results from the search for arrival direction anisotropy, including the observed large excess of events at the highest energies, seen in the region of the northern sky centered on Ursa Major. Based on the current results, the ``hot spot'' in particular, TA is pursuing the expansion of the surface array to four times its current size.

Magnetically Controlled Spasmodic Accretion during Star Formation. II. Results

NASA Astrophysics Data System (ADS)

Tassis, Konstantinos; Mouschovias, Telemachos Ch.

2005-01-01

The problem of the late accretion phase of the evolution of an axisymmetric, isothermal magnetic disk surrounding a forming star has been formulated in a companion paper. The ``central sink approximation'' is used to circumvent the problem of describing the evolution inside the opaque central region for densities greater than 1011 cm-3 and radii smaller than a few AU. Only the electrons are assumed to be attached to the magnetic field lines, and the effects of both negatively and positively charged grains are accounted for. After a mass of 0.1 Msolar accumulates in the central cell (forming star), a series of magnetically driven outflows and associated outward-propagating shocks form in a quasi-periodic fashion. As a result, mass accretion onto the protostar occurs in magnetically controlled bursts. We refer to this process as spasmodic accretion. The shocks propagate outward with supermagnetosonic speeds. The period of dissipation and revival of the outflow decreases in time, as the mass accumulated in the central sink increases. We evaluate the contribution of ambipolar diffusion to the resolution of the magnetic flux problem of star formation during the accretion phase, and we find it to be very significant albeit not sufficient to resolve the entire problem yet. Ohmic dissipation is completely negligible in the disk during this phase of the evolution. The protostellar disk is found to be stable against interchange-like instabilities, despite the fact that the mass-to-flux ratio has temporary local maxima.

Formation and evolution of dwarf elliptical galaxies - II. Spatially resolved star formation histories

NASA Astrophysics Data System (ADS)

Koleva, Mina; de Rijcke, Sven; Prugniel, Philippe; Zeilinger, Werner W.; Michielsen, Dolf

2009-07-01

We present optical Very Large Telescope spectroscopy of 16 dwarf elliptical galaxies (dEs) comparable in mass to NGC 205, and belonging to the Fornax cluster and to nearby groups of galaxies. Using full-spectrum fitting, we derive radial profiles of the SSP-equivalent ages and metallicities. We make a detailed analysis with ULYSS and STECKMAP of the star formation history in the core of the galaxies and in an aperture of one effective radius. We resolved the history into one to four epochs. The statistical significance of these reconstructions was carefully tested; the two programs give remarkably consistent results. The old stellar population of the dEs, which dominates their mass, is likely coeval with that of massive ellipticals or bulges, but the star formation efficiency is lower. Important intermediate age (1-5 Gyr) populations and frequently tails of star formation until recent times are detected. These histories are reminiscent of their lower mass dwarf spheroidal counterparts of the Local Group. Most galaxies (10/16) show significant metallicity gradients, with metallicity declining by 0.5 dex over one half-light radius on average. These gradients are already present in the old population. The flattened (or discy), rotating objects (6/16) have flat metallicity profiles. This may be consistent with a distinct origin for these galaxies or it may be due to their geometry. The central single stellar population equivalent age varies between 1 and 6 Gyr, with the age slowly increasing with radius in the vast majority of objects. The group and cluster galaxies have similar radial gradients and star formation histories. The strong and old metallicity gradients place important constraints on the possible formation scenarios of dEs. Numerical simulations of the formation of spherical low-mass galaxies reproduce these gradients, but they require a longer time for them to build up. A gentle depletion of the gas, by ram pressure stripping or starvation, could drive the

Pulsars Probe the Low-Frequency Gravitational Sky: Pulsar Timing Arrays Basics and Recent Results

NASA Astrophysics Data System (ADS)

Tiburzi, Caterina

2018-03-01

Pulsar Timing Array experiments exploit the clock-like behaviour of an array of millisecond pulsars, with the goal of detecting low-frequency gravitational waves. Pulsar Timing Array experiments have been in operation over the last decade, led by groups in Europe, Australia, and North America. These experiments use the most sensitive radio telescopes in the world, extremely precise pulsar timing models and sophisticated detection algorithms to increase the sensitivity of Pulsar Timing Arrays. No detection of gravitational waves has been made to date with this technique, but Pulsar Timing Array upper limits already contributed to rule out some models of galaxy formation. Moreover, a new generation of radio telescopes, such as the Five hundred metre Aperture Spherical Telescope and, in particular, the Square Kilometre Array, will offer a significant improvement to the Pulsar Timing Array sensitivity. In this article, we review the basic concepts of Pulsar Timing Array experiments, and discuss the latest results from the established Pulsar Timing Array collaborations.

Recent Discoveries and Future Challenges in Atmospheric Organic Chemistry.

PubMed

Glasius, Marianne; Goldstein, Allen H

2016-03-15

Earth's atmosphere contains a multitude of organic compounds, which differ by orders of magnitude regarding fundamental properties such as volatility, reactivity, and propensity to form cloud droplets, affecting their impact on global climate and human health. Despite recent major research efforts and advances, there are still substantial gaps in understanding of atmospheric organic chemistry, hampering efforts to understand, model, and mitigate environmental problems such as aerosol formation in both polluted urban and more pristine regions. The analytical toolbox available for chemists to study atmospheric organic components has expanded considerably during the past decade, opening new windows into speciation, time resolution and detection of reactive and semivolatile compounds at low concentrations. This has provided unprecedented opportunities, but also unveiled new scientific challenges. Specific groundbreaking examples include the role of epoxides in aerosol formation especially from isoprene, the importance of highly oxidized, reactive organics in air-surface processes (whether atmosphere-biosphere exchange or aerosols), as well as the extent of interactions of anthropogenic and biogenic emissions and the resulting impact on atmospheric organic chemistry.

Cobalamin Deficiency Results in Increased Production of Formate Secondary to Decreased Mitochondrial Oxidation of One-Carbon Units in Rats.

PubMed

MacMillan, Luke; Tingley, Garrett; Young, Sara K; Clow, Kathy A; Randell, Edward W; Brosnan, Margaret E; Brosnan, John T

2018-03-01

Formate is produced in mitochondria via the catabolism of serine, glycine, dimethylglycine, and sarcosine. Formate produced by mitochondria may be incorporated into the cytosolic folate pool where it can be used for important biosynthetic reactions. Previous studies from our lab have shown that cobalamin deficiency results in increased plasma formate concentrations. Our goal was to determine the basis for elevated formate in vitamin B-12 deficiency. Male Sprague Dawley rats were randomly assigned to consume either a cobalamin-replete (50 μg cobalamin/kg diet) or -deficient (no added cobalamin) diet for 6 wk. Formate production was measured in vivo and in isolated liver mitochondria from a variety of one-carbon precursors. We also measured the oxidation of [3-14C]-l-serine to 14CO2 in isolated rat liver mitochondria and the expression of hepatic genes involved in one-carbon unit and formate metabolism. Cobalamin-deficient rats produce formate at a rate 55% higher than that of replete rats. Formate production from serine was increased by 60% and from dimethylglycine and sarcosine by ∼200% in liver mitochondria isolated from cobalamin-deficient rats compared with cobalamin-replete rats. There was a 26% decrease in the 14CO2 produced by mitochondria from cobalamin-deficient rats. Gene expression analysis showed that 10-formyltetrahydrofolate dehydrogenase-cytosolic (Aldh1l1) and mitochondrial (Aldh1l2) expression were decreased by 40% and 60%, respectively, compared to control, while 10-formyltetrahydrofolate synthetase, mitochondrial, monofunctional (Mthfd1l) expression was unchanged. We propose that a bifurcation in mitochondrial one-carbon metabolism is a key control mechanism in determining the fate of one-carbon units, to formate or CO2. During cobalamin deficiency in rats the disposition of 10-formyl-tetrahydrofolate carbon is shifted in favor of formate production. This may represent a mechanism to generate more one-carbon units for the replenishment of the S

Formation of Penumbra in a Sample of Active Regions Observed by the SDO Satellite

NASA Astrophysics Data System (ADS)

Murabito, Mariarita; Zuccarello, Francesca; Guglielmino, Salvo L.; Romano, Paolo

2018-03-01

Recently, high-resolution observations improved our understanding of the penumbra formation process around sunspots. In particular, two aspects have been carefully investigated: whether the settlement of the penumbra can occur between the main opposite magnetic polarities where new magnetic flux is still emerging, and the establishment of the Evershed flow. In this paper, we present the analysis of twelve active regions (ARs) where both the penumbra formation and the onset of the Evershed flow were observed. We used data acquired by the Helioseismic and Magnetic Imager (HMI) instrument on board the Solar Dynamic Observatory (SDO) satellite analyzing continuum images, magnetograms, and Dopplergrams of the selected ARs. The results obtained in our sample provided the following information about the stable settlement of the penumbra: eight spots formed the first stable penumbral sector in the region between the two opposite polarities, and nine spots formed on the opposite side. Moreover, eleven sunpots showed an inverse Evershed flow (i.e., a plasma motion directed toward the protospot border) before the penumbra formation, which changes within 1–6 hr into the classical Evershed flow as soon as the penumbra forms. Comparing our results with recent observations, we are able to discriminate between the different ways of penumbra formation. Moreover, we suggest that the change from inverse Evershed flow, visible before the penumbra appears, into the classical Evershed flow may be a signature of the formation of penumbral filaments.

Recent Results of the Telescope Array Experiment

NASA Astrophysics Data System (ADS)

Ivanov, Dmitri

2015-04-01

The Telescope Array (TA) is the largest cosmic ray experiment in the northern hemisphere and covers 10 PeV to 100 EeV range. TA is a hybrid detector that uses air fluorescence detectors combined with a ground array. TA consists of 507 plastic scintillation counters on a 1.2km square grid, overlooked by 3 fluorescence detector stations, and measures cosmic rays above 1 EeV. TA has collected 6.5 years of data. Results from the TA low energy extension (TALE), which sees cosmic rays down to 10 PeV, will also be shown. This contribution will consist of three parts. First, we will present the cosmic ray energy spectrum measured over 4 decades in energy. Next, we will discuss the latest results of the measurements of cosmic ray mass composition by the TA fluorescence detectors. Finally, we will show the latest results of the TA anisotropy measurements at the highest energies, where we have seen a concentration of events, called the ``hotspot,'' centered in the Ursa Major. For the Telescope Array Collaboration. Done...processed 1261 records...10:46:59 Beginning APS data extraction...10:47:48

Formation of the First Stars and Blackholes

NASA Astrophysics Data System (ADS)

Yoshida, Naoki

2018-05-01

Cosmic reionization is thought to be initiated by the first generation of stars and blackholes. We review recent progress in theoretical studies of early structure formation. Cosmic structure formation is driven by gravitational instability of primeval density fluctuations left over from Big Bang. At early epochs, there are baryonic streaming motions with significant relative velocity with respect to dark matter. The formation of primordial gas clouds is typically delayed by the streaming motions, but then physical conditions for the so-called direct collapse blackhole formation are realized in proto-galactic halos. We present a promising model in which intermediate mass blackholes are formed as early as z = 30.

Analysis of Experimentation Results on University Graduates' Readiness Formation to Act in Extraordinary Situations

ERIC Educational Resources Information Center

Moloshavenko, Vera L.; Prozorova, Galina V.; Sienkiewicz, Lyudmila B.

2016-01-01

The article presents the experimentation on graduates' readiness formation to act in extraordinary situations conducted in the Tyumen Industrial University in training bachelors in "Oil and Gas Business". The criteria of graduates' readiness formation to act in extraordinary situations are the following: practicability, validity,…

On the chemical ladder of esters. Detection and formation of ethyl formate in the W51 e2 hot molecular core

NASA Astrophysics Data System (ADS)

Rivilla, V. M.; Beltrán, M. T.; Martín-Pintado, J.; Fontani, F.; Caselli, P.; Cesaroni, R.

2017-03-01

Context. In recent years, the detection of organic molecules with increasing complexity and potential biological relevance is opening the possibility to understand the formation of the building blocks of life in the interstellar medium. One of the families of molecules of substantial astrobiological interest are the esters. The simplest ester, methyl formate (CH3OCHO), is rather abundant in star-forming regions. The next step in the chemical complexity of esters is ethyl formate, C2H5OCHO. Despite the increase in sensitivity of current telescopes, the detection of complex molecules with more than ten atoms such as C2H5OCHO is still a challenge. Only two detections of this species have been reported so far, which strongly limits our understanding of how complex molecules are formed in the interstellar medium. New detections towards additional sources with a wide range of physical conditions are crucial to differentiate between competing chemical models based on dust grain surface and gas-phase chemistry. Aims: We have searched for ethyl formate towards the W51 e2 hot molecular core, one of the most chemically rich sources in the Galaxy and one of the most promising regions to study prebiotic chemistry, especially after the recent discovery of the P-O bond, key in the formation of DNA. Methods: We have analyzed a spectral line survey towards the W51 e2 hot molecular core, which covers 44 GHz in the 1, 2 and 3 mm bands, carried out with the IRAM 30 m telescope. Results: We report the detection of the trans and gauche conformers of ethyl formate. A local thermodynamic equilibrium analysis indicates that the excitation temperature is 78 ± 10 K and that the two conformers have similar source-averaged column densities of (2.0 ± 0.3) × 10-16 cm-2 and an abundance of 10-8. We compare for the first time the observed molecular abundances of ethyl formate with different competing chemical models based on grain surface and gas-phase chemistry. Conclusions: We propose that

Propofol, more than halothane, depresses electroencephalographic activation resulting from electrical stimulation in reticular formation.

PubMed

Antognini, J F; Bravo, E; Atherley, R; Carstens, E

2006-09-01

Halothane and propofol depress the central nervous system, and this is partly manifested by a decrease in electroencephalographic (EEG) activity. Little work has been performed to determine the differences between these anesthetics with regard to their effects on evoked EEG activity. We examined the effects of halothane and propofol on EEG responses to electrical stimulation of the reticular formation. Rats (n= 12) were anesthetized with either halothane or propofol, and EEG responses were recorded before and after electrical stimulation of the reticular formation. Two anesthetic concentrations were used (0.8 and 1.2 times the amount needed to prevent gross, purposeful movement in response to supramaximal noxious stimulation), and both anesthetics were studied in each rat using a cross-over design. Electrical stimulation in the reticular formation increased the spectral edge (SEF) and median edge (MEF) frequencies by approximately 1-2 Hz during halothane anesthesia at low and high concentrations. During propofol anesthesia, MEF increased at the low propofol infusion rate, but SEF was unaffected. At the high propofol infusion rate, SEF and MEF decreased following electrical stimulation in the reticular formation. At immobilizing concentrations, propofol produces a larger decrease than halothane in EEG responses to reticular formation stimulation, consistent with propofol having a more profound depressant effect on cortical and subcortical structures.

Identifying Risk Factors for Recent HIV Infection in Kenya Using a Recent Infection Testing Algorithm: Results from a Nationally Representative Population-Based Survey.

PubMed

Kim, Andrea A; Parekh, Bharat S; Umuro, Mamo; Galgalo, Tura; Bunnell, Rebecca; Makokha, Ernest; Dobbs, Trudy; Murithi, Patrick; Muraguri, Nicholas; De Cock, Kevin M; Mermin, Jonathan

2016-01-01

A recent infection testing algorithm (RITA) that can distinguish recent from long-standing HIV infection can be applied to nationally representative population-based surveys to characterize and identify risk factors for recent infection in a country. We applied a RITA using the Limiting Antigen Avidity Enzyme Immunoassay (LAg) on stored HIV-positive samples from the 2007 Kenya AIDS Indicator Survey. The case definition for recent infection included testing recent on LAg and having no evidence of antiretroviral therapy use. Multivariate analysis was conducted to determine factors associated with recent and long-standing infection compared to HIV-uninfected persons. All estimates were weighted to adjust for sampling probability and nonresponse. Of 1,025 HIV-antibody-positive specimens, 64 (6.2%) met the case definition for recent infection and 961 (93.8%) met the case definition for long-standing infection. Compared to HIV-uninfected individuals, factors associated with higher adjusted odds of recent infection were living in Nairobi (adjusted odds ratio [AOR] 11.37; confidence interval [CI] 2.64-48.87) and Nyanza (AOR 4.55; CI 1.39-14.89) provinces compared to Western province; being widowed (AOR 8.04; CI 1.42-45.50) or currently married (AOR 6.42; CI 1.55-26.58) compared to being never married; having had ≥ 2 sexual partners in the last year (AOR 2.86; CI 1.51-5.41); not using a condom at last sex in the past year (AOR 1.61; CI 1.34-1.93); reporting a sexually transmitted infection (STI) diagnosis or symptoms of STI in the past year (AOR 1.97; CI 1.05-8.37); and being aged <30 years with: 1) HSV-2 infection (AOR 8.84; CI 2.62-29.85), 2) male genital ulcer disease (AOR 8.70; CI 2.36-32.08), or 3) lack of male circumcision (AOR 17.83; CI 2.19-144.90). Compared to HIV-uninfected persons, factors associated with higher adjusted odds of long-standing infection included living in Coast (AOR 1.55; CI 1.04-2.32) and Nyanza (AOR 2.33; CI 1.67-3.25) provinces compared to

mzResults: An Interactive Viewer for Interrogation and Distribution of Proteomics Results*

PubMed Central

Webber, James T.; Askenazi, Manor; Marto, Jarrod A.

2011-01-01

The growing use of mass spectrometry in the context of biomedical research has been accompanied by an increased demand for distribution of results in a format that facilitates rapid and efficient validation of claims by reviewers and other interested parties. However, the continued evolution of mass spectrometry hardware, sample preparation methods, and peptide identification algorithms complicates standardization and creates hurdles related to compliance with journal submission requirements. Moreover, the recently announced Philadelphia Guidelines (1, 2) suggest that authors provide native mass spectrometry data files in support of their peer-reviewed research articles. These trends highlight the need for data viewers and other tools that work independently of manufacturers' proprietary data systems and seamlessly connect proteomics results with original data files to support user-driven data validation and review. Based upon our recently described API1-based framework for mass spectrometry data analysis (3, 4), we created an interactive viewer (mzResults) that is built on established database standards and enables efficient distribution and interrogation of results associated with proteomics experiments, while also providing a convenient mechanism for authors to comply with data submission standards as described in the Philadelphia Guidelines. In addition, the architecture of mzResults supports in-depth queries of the native mass spectrometry files through our multiplierz software environment. We use phosphoproteomics data to illustrate the features and capabilities of mzResults. PMID:21266631

Formation of the Isthmus of Panama

PubMed Central

O’Dea, Aaron; Lessios, Harilaos A.; Coates, Anthony G.; Eytan, Ron I.; Restrepo-Moreno, Sergio A.; Cione, Alberto L.; Collins, Laurel S.; de Queiroz, Alan; Farris, David W.; Norris, Richard D.; Stallard, Robert F.; Woodburne, Michael O.; Aguilera, Orangel; Aubry, Marie-Pierre; Berggren, William A.; Budd, Ann F.; Cozzuol, Mario A.; Coppard, Simon E.; Duque-Caro, Herman; Finnegan, Seth; Gasparini, Germán M.; Grossman, Ethan L.; Johnson, Kenneth G.; Keigwin, Lloyd D.; Knowlton, Nancy; Leigh, Egbert G.; Leonard-Pingel, Jill S.; Marko, Peter B.; Pyenson, Nicholas D.; Rachello-Dolmen, Paola G.; Soibelzon, Esteban; Soibelzon, Leopoldo; Todd, Jonathan A.; Vermeij, Geerat J.; Jackson, Jeremy B. C.

2016-01-01

The formation of the Isthmus of Panama stands as one of the greatest natural events of the Cenozoic, driving profound biotic transformations on land and in the oceans. Some recent studies suggest that the Isthmus formed many millions of years earlier than the widely recognized age of approximately 3 million years ago (Ma), a result that if true would revolutionize our understanding of environmental, ecological, and evolutionary change across the Americas. To bring clarity to the question of when the Isthmus of Panama formed, we provide an exhaustive review and reanalysis of geological, paleontological, and molecular records. These independent lines of evidence converge upon a cohesive narrative of gradually emerging land and constricting seaways, with formation of the Isthmus of Panama sensu stricto around 2.8 Ma. The evidence used to support an older isthmus is inconclusive, and we caution against the uncritical acceptance of an isthmus before the Pliocene. PMID:27540590

First Results from a Hardware-in-the-Loop Demonstration of Closed-Loop Autonomous Formation Flying

NASA Technical Reports Server (NTRS)

Gill, E.; Naasz, Bo; Ebinuma, T.

2003-01-01

A closed-loop system for the demonstration of autonomous satellite formation flying technologies using hardware-in-the-loop has been developed. Making use of a GPS signal simulator with a dual radio frequency outlet, the system includes two GPS space receivers as well as a powerful onboard navigation processor dedicated to the GPS-based guidance, navigation, and control of a satellite formation in real-time. The closed-loop system allows realistic simulations of autonomous formation flying scenarios, enabling research in the fields of tracking and orbit control strategies for a wide range of applications. The autonomous closed-loop formation acquisition and keeping strategy is based on Lyapunov's direct control method as applied to the standard set of Keplerian elements. This approach not only assures global and asymptotic stability of the control but also maintains valuable physical insight into the applied control vectors. Furthermore, the approach can account for system uncertainties and effectively avoids a computationally expensive solution of the two point boundary problem, which renders the concept particularly attractive for implementation in onboard processors. A guidance law has been developed which strictly separates the relative from the absolute motion, thus avoiding the numerical integration of a target trajectory in the onboard processor. Moreover, upon using precise kinematic relative GPS solutions, a dynamical modeling or filtering is avoided which provides for an efficient implementation of the process on an onboard processor. A sample formation flying scenario has been created aiming at the autonomous transition of a Low Earth Orbit satellite formation from an initial along-track separation of 800 m to a target distance of 100 m. Assuming a low-thrust actuator which may be accommodated on a small satellite, a typical control accuracy of less than 5 m has been achieved which proves the applicability of autonomous formation flying techniques to

Recent Radiation Test Results for Power MOSFETs

NASA Technical Reports Server (NTRS)

Lauenstein, Jean-Marie; Topper, Alyson D.; Casey, Megan C.; Wilcox, Edward P.; Phan, Anthony M.; Kim, Hak S.; LaBel, Kenneth A.

2013-01-01

Single-event effect (SEE) and total ionizing dose (TID) test results are presented for various hardened and commercial power metal-oxide-semiconductor field effect transistors (MOSFETs), including vertical planar, trench, superjunction, and lateral process designs.

Supercoil Formation During DNA Melting

NASA Astrophysics Data System (ADS)

Sayar, Mehmet; Avsaroglu, Baris; Kabakcioglu, Alkan

2009-03-01

Supercoil formation plays a key role in determining the structure-function relationship in DNA. Biological and technological processes, such as protein synthesis, polymerase chain reaction, and microarrays relys on separation of the two strands in DNA, which is coupled to the unwinding of the supercoiled structure. This problem has been studied theoretically via Peyrard-Bishop and Poland-Scheraga type models, which include a simple representation of the DNA structural properties. In recent years, computational models, which provide a more realtistic representaion of DNA molecule, have been used to study the melting behavior of short DNA chains. Here, we will present a new coarse-grained model of DNA which is capable of simulating sufficiently long DNA chains for studying the supercoil formation during melting, without sacrificing the local structural properties. Our coarse-grained model successfully reproduces the local geometry of the DNA molecule, such as the 3'-5' directionality, major-minor groove structure, and the helical pitch. We will present our initial results on the dynamics of supercoiling during DNA melting.

Recent Results from Epitaxial Growth on Step Free 4H-SiC Mesas

NASA Technical Reports Server (NTRS)

Neudeck, Philip G.; Trunek, Andrew J.; Spry, David J.; Powell, J. Anthony; Du, Hui; Skowronski, Marek; Bassim, Nabil D.; Mastro, Michael A.; Twigg, Mark E.; Holm, Ronald T.;

Recent Results From the NOAA/ESRL GMD Tall Tower Network

NASA Astrophysics Data System (ADS)

Andrews, A. E.; Tans, P. P.; Peters, W.; Hirsch, A.; Sweeney, C.; Petron, G.; Kofler, J.; Zhao, C.; Masarie, K.; Wofsy, S. C.; Matross, D. M.; Mahadevan, P.; Longo, M.; Gerbig, C.; Lin, J. C.

2006-12-01

We will present a summary of new results from NOAA Earth System Research Laboratory`s Tall Tower greenhouse gas monitoring network. The tower network is operated by the Global Monitoring Division, which also maintains the global Cooperative Air Sampling network and a network of aircraft profiling sites over North America. Tall tower CO2 mixing ratio measurements are sensitive to upwind fluxes over scales of hundreds of kilometers, and the primary objective of the tower network is to obtain regionally representative carbon flux estimates for the North American continent. Mixing ratios of CO2 and CO are measured semi-continuously at the towers, and the KWKT-TV tower site near Moody, TX has recently also been equipped with sensors to measure radon and O3. Daily flask samples are collected at the KWKT tower and analyzed for CO2, CO, CH4, SF6, N2O, H2, stable isotopes of CO2 and CH4, COS, and a variety of halocarbon and hydrocarbon species. Daily flask sampling will be implemented at all tower sites within the next few years. We have used the Stochastic Time Inverted Lagrangian Transport (STILT) model to investigate upwind influences on the tower observations. CO measurements provide an indicator of polluted air masses, and we will present a summary of the frequency and origin of pollution events observed at the towers. We will present an analysis of the primary factors contributing to observed CO2 variability along with average seasonal and diurnal cycles of CO2 at the tower sites. Tower measurements are being used to evaluate atmospheric transport models in the context of the Transcom Continuous experiment and are an important constraint for CO2 data assimilation systems that produce regional to global carbon flux estimates with up to weekly resolution.

Recent results on output feedback problems

NASA Technical Reports Server (NTRS)

Byrnes, C. I.

1980-01-01

Given a real linear system sigma = (A, B, C) with m inputs, p outputs and degree n, the problem of generic pole placement by output feedback is studied, which is to compute the constant C(m,p) such that the inequality C(m,p) not less than n is necessary and sufficient for generically positioning the poles of the generic linear system by constant output feedback. A constant C prime (m,p) is determined, which gives a sufficient condition for generic pole placement and which, to the best of the author's knowledge, is at least as good an estimate of C(m,p) as any in the literature. Some results on the construction of solutions in case mp = n are announced, based on the degree formula of Brockett and Byrnes and the Galois theory. In particular, a question raised by Anderson, Bose, and Jury, on the existence of a rational procedure for computing the feedback law from the desired characteristic polynomial is answered.

Planet Formation

NASA Technical Reports Server (NTRS)

Lissauer, Jack J.; Fonda, Mark (Technical Monitor)

2002-01-01

Modern theories of star and planet formation and of the orbital stability of planetary systems are described and used to discuss possible characteristics of undiscovered planetary systems. The most detailed models of planetary growth are based upon observations of planets and smaller bodies within our own Solar System and of young stars and their environments. Terrestrial planets are believed to grow via pairwise accretion until the spacing of planetary orbits becomes large enough that the configuration is stable for the age of the system. Giant planets begin their growth as do terrestrial planets, but they become massive enough that they are able to accumulate substantial amounts of gas before the protoplanetary disk dissipates. These models predict that rocky planets should form in orbit about most single stars. It is uncertain whether or not gas giant planet formation is common, because most protoplanetary disks may dissipate before solid planetary cores can grow large enough to gravitationally trap substantial quantities of gas. A potential hazard to planetary systems is radial decay of planetary orbits resulting from interactions with material within the disk. Planets more massive than Earth have the potential to decay the fastest, and may be able to sweep up smaller planets in their path. The implications of the giant planets found in recent radial velocity searches for the abundances of habitable planets are discussed, and the methods that are being used and planned for detecting and characterizing extrasolar planets are reviewed.

The formation of co-orbital planets and their resulting transit signatures

NASA Astrophysics Data System (ADS)

Granados Contreras, Agueda Paula; Boley, Aaron

2018-04-01

Systems with Tightly-packed Inner Planets (STIPs) are metastable, exhibiting sudden transitions to an unstable state that can potentially lead to planet consolidation. When these systems are embedded in a gaseous disc, planet-disc interactions can significantly reduce the frequency of instabilities, and if they do occur, disc torques alter the dynamical outcomes. We ran a suite of N-body simulations of synthetic 6-planet STIPs using an independent implementation of IAS15 that includes a prescription for gaseous tidal damping. The algorithm is based on the results of disc simulations that self-consistently evolve gas and planets. Even for very compact configurations, the STIPS are resistant to instability when gas is present. However, instability can still occur, and in some cases, the combination of system instability and gaseous damping leads to the formation of co-orbiting planets that are stable even when gas damping is removed. While rare, such systems should be detectable in transit surveys, although the dynamics of the system can make the transit signature difficult to identify.

Recent discoveries from the cosmic microwave background: a review of recent progress

NASA Astrophysics Data System (ADS)

Staggs, Suzanne; Dunkley, Jo; Page, Lyman

2018-04-01

Measurements of the anisotropies in the cosmic microwave background (CMB) radiation have provided a wealth of information about the cosmological model that describes the contents and evolution of the universe. These data have led to a standard model described by just six parameters. In this review we focus on discoveries made in the past decade from satellite and ground-based experiments, and look ahead to those anticipated in the coming decade. We provide an introduction to the key CMB observables including temperature and polarization anisotropies, and describe recent progress towards understanding the initial conditions of structure formation, and establishing the properties of the contents of the universe including neutrinos. Results are now being derived both from the primordial CMB signal that traces the behavior of the universe at 400 000 years of cosmic time, as well as from the signals imprinted at later times due to scattering from galaxy clusters, from the motion of electrons in the ionized universe, and from the gravitational lensing of the CMB photons. We describe current experimental methods to measure the CMB, particularly focusing on details relevant for ground and balloon-based instruments, and give an overview of the broad data analysis methods required to convert measurements of the microwave sky into cosmological parameters.

Recent discoveries from the cosmic microwave background: a review of recent progress.

PubMed

Staggs, Suzanne; Dunkley, Jo; Page, Lyman

2018-04-01

Measurements of the anisotropies in the cosmic microwave background (CMB) radiation have provided a wealth of information about the cosmological model that describes the contents and evolution of the universe. These data have led to a standard model described by just six parameters. In this review we focus on discoveries made in the past decade from satellite and ground-based experiments, and look ahead to those anticipated in the coming decade. We provide an introduction to the key CMB observables including temperature and polarization anisotropies, and describe recent progress towards understanding the initial conditions of structure formation, and establishing the properties of the contents of the universe including neutrinos. Results are now being derived both from the primordial CMB signal that traces the behavior of the universe at 400 000 years of cosmic time, as well as from the signals imprinted at later times due to scattering from galaxy clusters, from the motion of electrons in the ionized universe, and from the gravitational lensing of the CMB photons. We describe current experimental methods to measure the CMB, particularly focusing on details relevant for ground and balloon-based instruments, and give an overview of the broad data analysis methods required to convert measurements of the microwave sky into cosmological parameters.

POX 186: A Dwarf Galaxy in the Process of Formation?

NASA Astrophysics Data System (ADS)

Corbin, Michael R.; Vacca, William D.

2002-12-01

We present deep U-, V-, and I-band images of the ``ultracompact'' blue dwarf galaxy POX 186 obtained with the Planetary Camera 2 of the Hubble Space Telescope. We have also obtained a near-ultraviolet spectrum of the object with the Space Telescope Imaging Spectrograph and combine this with a new ground-based optical spectrum. The images confirm the galaxy to be extremely small, with a maximum extent of only 300 pc, a luminosity of ~10-4L*, and an estimated mass of ~107 Msolar. Its morphology is highly asymmetric, with a tail of material on its western side that may be tidal in origin. The U-band image shows this tail to be part of a stream of material in which stars have recently formed. Most of the star formation in the galaxy is, however, concentrated in a central, compact (d~10-15 pc) star cluster. We estimate this cluster to have a total mass of ~105 Msolar, to be forming stars at a rate of less than 0.05 yr-1, and to have a maximum age of a few million years. The outer regions of the galaxy are significantly redder than the cluster, with V-I colors consistent with a population dominated by K and M stars. From our analysis of the optical spectrum we find the galaxy to have a metallicity Z~=0.06 Zsolar and to contain a significant amount of internal dust [E(B-V)~=0.28] both values agree with previous estimates. While these results rule out earlier speculation that POX 186 is a protogalaxy, its morphology, mass, and active star formation suggest that it represents a recent (within ~108 yr) collision between two clumps of stars of subgalactic size (~100 pc). POX 186 may thus be a very small dwarf galaxy that, dynamically speaking, is still in the process of formation. This interpretation is supported by the fact that it resides in a void, so its morphology cannot be explained as the result of an encounter with a more massive galaxy. Clumps of stars this small may represent the building blocks required by hierarchical models of galaxy formation, and these results

Recent Results from the Daya Bay Experiment

NASA Astrophysics Data System (ADS)

Yu, Z. Y.; Daya Bay Collaboration

2017-09-01

The Daya Bay reactor neutrino experiment was designed to precisely measure the neutrino oscillation parameter θ 13 via the relative comparison of neutrino rates and spectra at different baselines. Eight identically designed detectors were deployed in two near experimental halls and a far hall. Six 2.9 GWth nuclear power reactors served as intense {\\bar ν _e} sources. Since Dec. 2011, the experiment has been running stably. The latest neutrino oscillation results were based on 1230 days of data. Analysis using a three-flavor oscillation model yielded sin22θ 13 = 0.0841 ± 0.0027(stat.) ± 0.0019(syst.), and effective neutrino mass-squared difference ≤ft| {Δ mee^2} \\right| = ≤ft( {2.50 +/- 0.06≤ft( {stat.} \\right) +/- 0.06≤ft( {syst.} \\right)} \\right) × {10 - 3}e{V^2}. Besides, results from the absolute measurement of reactor {\\bar ν _e} flux and energy spectrum, and a search for a light sterile neutrino are also presented.

Cosmic Star Formation: A Simple Model of the SFRD(z)

NASA Astrophysics Data System (ADS)

Chiosi, Cesare; Sciarratta, Mauro; D’Onofrio, Mauro; Chiosi, Emanuela; Brotto, Francesca; De Michele, Rosaria; Politino, Valeria

2017-12-01

We investigate the evolution of the cosmic star formation rate density (SFRD) from redshift z = 20 to z = 0 and compare it with the observational one by Madau and Dickinson derived from recent compilations of ultraviolet (UV) and infrared (IR) data. The theoretical SFRD(z) and its evolution are obtained using a simple model that folds together the star formation histories of prototype galaxies that are designed to represent real objects of different morphological type along the Hubble sequence and the hierarchical growing of structures under the action of gravity from small perturbations to large-scale objects in Λ-CDM cosmogony, i.e., the number density of dark matter halos N(M,z). Although the overall model is very simple and easy to set up, it provides results that mimic results obtained from highly complex large-scale N-body simulations well. The simplicity of our approach allows us to test different assumptions for the star formation law in galaxies, the effects of energy feedback from stars to interstellar gas, the efficiency of galactic winds, and also the effect of N(M,z). The result of our analysis is that in the framework of the hierarchical assembly of galaxies, the so-called time-delayed star formation under plain assumptions mainly for the energy feedback and galactic winds can reproduce the observational SFRD(z).

Common Data Format: New XML and Conversion Tools

NASA Astrophysics Data System (ADS)

Han, D. B.; Liu, M. H.; McGuire, R. E.

2002-12-01

Common Data Format (CDF) is a self-describing platform-independent data format for storing, accessing, and manipulating scalar and multidimensional scientific data sets. Significant benefit has accrued to specific science communities from their use of standard formats within those communities. Examples include the International Solar Terrestrial Physics (ISTP) community in using CDF for traditional space physics data (fields, particles and plasma, waves, and images), the worldwide astronomical community in using FITS (Flexible Image Transport System) for solar data (primarily spectral images), the NASA Planetary community in using Planetary Data System (PDS) Labels, and the earth science community in using Hierarchical Data Format (HDF). Scientific progress in solar-terrestrial physics continues to be impeded by the multiplicity of available standards for data formats and dearth of general data format translators. As a result, scientists today spend a significant amount of time translating data into the format they are familiar with for their research. To minimize this unnecessary data translation time and to allow more research time, the CDF office located at GSFC National Space Science Data Center (NSSDC) has developed HDF-to-CDF and FITS-to-CDF translators, and employed the eXtensible Markup Language (XML) technology to facilitate and promote data interoperability within the space science community. We will present the current status of the CDF work including the conversion tools that have been recently developed, conversion tools that are planned in the near future, share some of the XML experiences, and use the discussion to gain community feedback to our planned future work.

Methionine peptide formation under primordial earth conditions.

PubMed

Li, Feng; Fitz, Daniel; Fraser, Donald G; Rode, Bernd M

2008-01-01

According to recent research on the origin of life it seems more and more likely that amino acids and peptides were among the first biomolecules formed on earth and that a peptide/protein world was thus a key starting point in evolution towards life. Salt-induced Peptide Formation (SIPF) has repeatedly been shown to be the most universal and plausible peptide-forming reaction currently known under prebiotic conditions and forms peptides from amino acids with the help of copper ions and sodium chloride. In this paper we present experimental results for salt-induced peptide formation from methionine. This is the first time that a sulphur-containing amino acid was investigated in this reaction. The possible catalytic effects of glycine and L-histidine in this reaction were also investigated and a possible distinction between the L- and D-forms of methionine was studied as well.

[Mechanisms of immune deposit formation in glomerulonephritis].

PubMed

Bussolati, B; Camussi, G

1996-03-01

Recent experimental studies allowed the identification of several mechanisms of immune deposit formation, which are able to reproduce the morphological and clinical pattern of human glomerulonephritis. Moreover, it was shown that most of the lesions considered, in the past, as due to circulating immune complexes (IC), are instead caused by the "in situ" formation of IC. As a result of these studies, the following schematic classification was proposed: 1) immune deposits formed by glomerular localization of IC primarily formed in the circulation; 2) immune deposits formed "in situ" by reaction of circulating antibodies with fixed structural antigens; 3) immune deposits formed "in situ" by antibodies reactive with movable structural antigens; 4) immune deposits formed "in situ" by antibodies reactive with sequestered antigens leaking out of tissues; 5) IC formed "in situ" by antibodies reactive with exogenous or non-glomerular endogenous antigens planted in the glomeruli; 6) ANCA-associated glomerular disease.

Stellar activity and coronal heating: an overview of recent results

PubMed Central

Testa, Paola; Saar, Steven H.; Drake, Jeremy J.

2015-01-01

Observations of the coronae of the Sun and of solar-like stars provide complementary information to advance our understanding of stellar magnetic activity, and of the processes leading to the heating of their outer atmospheres. While solar observations allow us to study the corona at high spatial and temporal resolution, the study of stellar coronae allows us to probe stellar activity over a wide range of ages and stellar parameters. Stellar studies therefore provide us with additional tools for understanding coronal heating processes, as well as the long-term evolution of solar X-ray activity. We discuss how recent studies of stellar magnetic fields and coronae contribute to our understanding of the phenomenon of activity and coronal heating in late-type stars. PMID:25897087

Micro-fabric damages in Boom Clay inferred from cryo-BIB-SEM experiment: recent results

NASA Astrophysics Data System (ADS)

Desbois, Guillaume; Schmatz, Joyce; Klaver, Jop; Urai, Janos L.

2017-04-01

The Boom Clay is considered as a potential host rock in Belgium for nuclear waste disposal in a deep geological formation. One of the keys to understand the long-term performance of such a host rock is the fundamental understanding of coupling between microstructural evolution, poromechanical behaviour and the state of hydration of the system. At in situ conditions, Boom Clay is a nearly water-saturated (>94%) clay-rich geomaterial. Subsequently, for measurement of mechanical and transport properties in laboratory, cores of Boom Clay are vacuum-packed in Al-coated-poly-ethylene barrier foil to be best preserved at original hydric state. Because clay microstructures are very sensitive to dehydration, the validity of investigations done on such preserved or/and dried samples is often questionable. Desbois et al. (2009, 2013, 2014) showed the possibility to image fluid-filled porosity in Boom Clay, by using the FIB-cryo-SEM (FIB: Focussed Ion Beam) and FIB-cryo-SEM (BIB: Broad Ion Beam) techniques. However, surprisingly in Desbois et al. (2014), BIB-cryo-SEM experiments on Boom Clay, shown that the majority of the pores were fluid-free, contrasting with result in Desbois et al. (2009). In Desbois et al. (2014), several reasons were discussed to explain such discrepancies. The likely ones are the sealing efficiency of the Al-barrier foil at long term and the volume expansion due to the release of in-situ stress after core extraction, contributing both to dehydration and microfabric damage. This contribution presents the newest results based on cryo-BIB-SEM. Small pieces (30 mm3) of Boom Clay were preserved in liquid nitrogen after the core extraction at the MOL/Dessel Underground Research Laboratory in Belgium. A maximum of ten minutes time span was achieved between opening the core, the sub-sample extraction and the quenching of sub-samples in liquid nitrogen. First results show that all pores visible at cryo-SEM resolution are water saturated. However, water

Overexpression of BMP3 in the developing skeleton alters endochondral bone formation resulting in spontaneous rib fractures.

PubMed

Gamer, Laura W; Cox, Karen; Carlo, Joelle M; Rosen, Vicki

2009-09-01

Bone morphogenetic protein-3 (BMP) has been identified as a negative regulator in the skeleton as mice lacking BMP3 have increased bone mass. To further understand how BMP3 mediates bone formation, we created transgenic mice overexpressing BMP3 using the type I collagen promoter. BMP3 transgenic mice displayed spontaneous rib fractures that were first detected at E17.0. The fractures were due to defects in differentiation of the periosteum and late hypertrophic chondrocytes resulting in thinner cortical bone with decreased mineralization. As BMP3 modulates BMP and activin signaling through ActRIIB, we examined the ribs of ActRIIB receptor knockout mice and found they had defects in late chondrogenesis and mineralization similar to BMP3 transgenic mice. These data suggest that BMP3 exerts its effects in the skeleton by altering signaling through ActRIIB in chondrocytes and the periosteum, and this results in defects in bone collar formation and late hypertrophic chondrocyte maturation leading to decreased mineralization and less bone. 2009 Wiley-Liss, Inc.

Enzyme-Mediated Conversion of Flavin Adenine Dinucleotide (FAD) to 8-Formyl FAD in Formate Oxidase Results in a Modified Cofactor with Enhanced Catalytic Properties.

PubMed

Robbins, John M; Souffrant, Michael G; Hamelberg, Donald; Gadda, Giovanni; Bommarius, Andreas S

2017-07-25

Flavins, including flavin adenine dinucleotide (FAD), are fundamental catalytic cofactors that are responsible for the redox functionality of a diverse set of proteins. Alternatively, modified flavin analogues are rarely found in nature as their incorporation typically results in inactivation of flavoproteins, thus leading to the disruption of important cellular pathways. Here, we report that the fungal flavoenzyme formate oxidase (FOX) catalyzes the slow conversion of noncovalently bound FAD to 8-formyl FAD and that this conversion results in a nearly 10-fold increase in formate oxidase activity. Although the presence of an enzyme-bound 8-formyl FMN has been reported previously as a result of site-directed mutagenesis studies of lactate oxidase, FOX is the first reported case of 8-formyl FAD in a wild-type enzyme. Therefore, the formation of the 8-formyl FAD cofactor in formate oxidase was investigated using steady-state kinetics, site-directed mutagenesis, ultraviolet-visible, circular dichroism, and fluorescence spectroscopy, liquid chromatography with mass spectrometry, and computational analysis. Surprisingly, the results from these studies indicate not only that 8-formyl FAD forms spontaneously and results in the active form of FOX but also that its autocatalytic formation is dependent on a nearby arginine residue, R87. Thus, this work describes a new enzyme cofactor and provides insight into the little-understood mechanism of enzyme-mediated 8α-flavin modifications.

KASCADE-Grande Review, Recent Results, Future Endeavors

NASA Astrophysics Data System (ADS)

Schoo, S.; Apel, W. D.; Arteaga-Velázquez, J. C.; Beck, K.; Bertaina, M.; Blümer, J.; Bozdog, H.; Brancus, I. M.; Cantoni, E.; Chiavassa, A.; Cossavella, F.; Daumiller, K.; de Souza, V.; Di Pierro, F.; Doll, P.; Engel, R.; Fuhrmann, D.; Gherghel-Lascu, A.; Gils, H. J.; Glasstetter, R.; Grupen, C.; Haungs, A.; Heck, D.; Hörandel, J. R.; Huber, D.; Huege, T.; Kampert, K.-H.; Kang, D.; Klages, H. O.; Link, K.; Łuczak, P.; Mathes, H. J.; Mayer, H. J.; Milke, J.; Mitrica, B.; Morello, C.; Oehlschläger, J.; Ostapchenko, S.; Palmieri, N.; Petcu, M.; Pierog, T.; Rebel, H.; Roth, M.; Schieler, H.; Schröder, F. G.; Sima, O.; Toma, G.; Trinchero, G. C.; Ulrich, H.; Weindl, A.; Wochele, J.; Zabierowski, J.

A detailed knowledge of the energy spectrum and composition of cosmic rays (CRs) is the most important source of information for solving the riddle of the origin of CRs. The KASCADE experiment and its extension KASCADE-Grande have contributed much to the current knowledge about both the spectrum and composition in the energy range from around 1 PeV to 1 EeV. One of the most important results of the KASCADE experiment is the connection of the knee at a few PeV to a decrease in the flux of light primaries. Later, KASCADE-Grande found a knee-like structure also in the spectrum of heavy elements at around 90 PeV and an ankle-like feature in the spectrum of light elements just above 100 PeV. In this contribution a short review of the experiment will be followed by an overview on the current results on spectrum and composition of CRs and a summary of the further activities within the KASCADE-Grande collaboration related to both, data analysis and data publication.

A Summary of the NASA Lightning Nitrogen Oxides Model (LNOM) and Recent Results

NASA Technical Reports Server (NTRS)

Koshak, William; Peterson, Harld

2011-01-01

The NASA Marshall Space Flight Center introduced the Lightning Nitrogen Oxides Model (LNOM) a couple of years ago to combine routine state-of-the-art measurements of lightning with empirical laboratory results of lightning NOx production. The routine measurements included VHF lightning source data [such as from the North Alabama Lightning Mapping Array (LMA)], and ground flash location, peak current, and stroke multiplicity data from the National Lightning Detection Network(TradeMark) (NLDN). Following these initial runs of LNOM, the model was updated to include several non-return stroke lightning NOx production mechanisms, and provided the impact of lightning NOx on an August 2006 run of CMAQ. In this study, we review the evolution of the LNOM in greater detail and discuss the model?s latest upgrades and applications. Whereas previous applications were limited to five summer months of data for North Alabama thunderstorms, the most recent LNOM analyses cover several years. The latest statistics of ground and cloud flash NOx production are provided.

The National SAT Validity Study: Sharing Results from Recent College Success Research

ERIC Educational Resources Information Center

Shaw, Emily J.; McKenzie, Elizabeth

2010-01-01

[Slides] presented at the annual conference of the Southern Association for College Admission Counseling, April 2010. This presentation summarizes recent research from the national SAT Validity Study and includes information on the Admitted Class Evaluation Service (ACES) system and how ACES can help institutions conduct their own validity…

UNDERSTANDING PCDD/F FORMATION AND SOURCES

EPA Science Inventory

Recent work at the U. S. EPA has examined fundamental concepts regarding formation and minimization of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDDs/Fs) in combustion scenarios. This paper summarizes some of these main findings, drawing on work from multiple studies....

Results from recent NASA tire thermal studies

NASA Technical Reports Server (NTRS)

Mccarty, J. L.

1983-01-01

The testing technique and some results from an experimental study to determine tire temperature profiles to aid in defining the strength and fatigue limitations of the tire carcass structure are described. This effort is part of a program to explore analytically and through experiment the temperature distribution in an aircraft tire during free roll and braked and yawed rolling conditions.

The "Academization" of the German Qualification System: Recent Developments in the Relationships between Vocational Training and Higher Education in Germany

ERIC Educational Resources Information Center

Wolter, Andrä; Kerst, Christian

2015-01-01

The traditional German model of skill formation was based on the rather strict segmentation between vocational training and higher education. However, during recent years this differentiation has slowly dissolved, partly by politically motivated developments to increase the permeability between both sectors and partly as a result of latent changes…

Formation and spatial distribution of hypervelocity stars in AGN outflows

NASA Astrophysics Data System (ADS)

Wang, Xiawei; Loeb, Abraham

2018-05-01

We study star formation within outflows driven by active galactic nuclei (AGN) as a new source of hypervelocity stars (HVSs). Recent observations revealed active star formation inside a galactic outflow at a rate of ∼ 15M⊙yr-1 . We verify that the shells swept up by an AGN outflow are capable of cooling and fragmentation into cold clumps embedded in a hot tenuous gas via thermal instabilities. We show that cold clumps of ∼ 103 M⊙ are formed within ∼ 105 yrs. As a result, stars are produced along outflow's path, endowed with the outflow speed at their formation site. These HVSs travel through the galactic halo and eventually escape into the intergalactic medium. The expected instantaneous rate of star formation inside the outflow is ∼ 4 - 5 orders of magnitude greater than the average rate associated with previously proposed mechanisms for producing HVSs, such as the Hills mechanism and three-body interaction between a star and a black hole binary. We predict the spatial distribution of HVSs formed in AGN outflows for future observational probe.

Core formation in the early solar system through percolation: 4-D in-situ visualization of melt migration

NASA Astrophysics Data System (ADS)

Bromiley, G.; Berg, M.; Le Godec, Y.; Mezouar, N.; Atwood, R. C.; Phillipe, J.

2015-12-01

Although core formation was a key stage in the evolution of terrestrial planets, the physical processes which resulted in segregation of iron and silicate remain poorly understood. Formation of a silicate magma oceans provides an obvious mechanism for segregation of core-forming liquids, although recent work has strengthened arguments for a complex, multi-stage model of core formation. Extreme pressure1 and the effects of deformation2 have both been shown to promote percolation of Fe-rich melts in a solid silicate matrix, providing mechanisms for early, low temperature core-formation. However, the efficiency of these processes remains untested and we lack meaningful experimental data on resulting melt segregation velocities. Arguments regarding the efficiency of core formation through percolation of Fe-rich melts in solid silicate are based on simple, empirical models. Here, we review textural evidence from recent experiments which supports early core formation driven by deformation-aided percolation of Fe-rich melts. We then present results of novel in-situ synchrotron studies designed to provide time-resolved 3-D microimaging of percolating melt in model systems under extreme conditions. Under low strain rates characteristic of deformation-aided core formation, segregation of metallic (core-forming) melts by percolation is driven by stress gradients. This is expected to ultimately result in channelization and efficient segregation of melts noted in high-strain, low pressure experiments3. In-situ visualization also demonstrates that percolation of viscous metallic melts is surprisingly rapid. A combination of melt channelization and hydraulic fracture results in rapid, episodic melt migration, even over the limited time scale of experiments. The efficiency of this process depends strongly on the geometry of the melt network and is scaled to grain size in the matrix. We use both in-situ visualization and high-resolution ex-situ analysis to provide accurate

Kinetics of Internal-Loop Formation in Polypeptide Chains: A Simulation Study

PubMed Central

Doucet, Dana; Roitberg, Adrian; Hagen, Stephen J.

2007-01-01

The speed of simple diffusional motions, such as the formation of loops in the polypeptide chain, places one physical limit on the speed of protein folding. Many experimental studies have explored the kinetics of formation of end-to-end loops in polypeptide chains; however, protein folding more often requires the formation of contacts between interior points on the chain. One expects that, for loops of fixed contour length, interior loops will form more slowly than end-to-end loops, owing to the additional excluded volume associated with the “tails”. We estimate the magnitude of this effect by generating ensembles of randomly coiled, freely jointed chains, and then using the theory of Szabo, Schulten, and Schulten to calculate the corresponding contact formation rates for these ensembles. Adding just a few residues, to convert an end-to-end loop to an internal loop, sharply decreases the contact rate. Surprisingly, the relative change in rate increases for a longer loop; sufficiently long tails, however, actually reverse the effect and accelerate loop formation slightly. Our results show that excluded volume effects in real, full-length polypeptides may cause the rates of loop formation during folding to depart significantly from the values derived from recent loop-formation experiments on short peptides. PMID:17208979

CAVIAR: an R package for checking, displaying and processing wood-formation-monitoring data.

PubMed

Rathgeber, Cyrille B K; Santenoise, Philippe; Cuny, Henri E

2018-05-19

In the last decade, the pervasive question of climate change impacts on forests has revived investigations on intra-annual dynamics of wood formation, involving disciplines such as plant ecology, tree physiology and dendrochronology. This resulted in the creation of many research groups working on this topic worldwide and a rapid increase in the number of studies and publications. Wood-formation-monitoring studies are generally based on a common conceptual model describing xylem cell formation as the succession of four differentiation phases (cell division, cell enlargement, cell wall thickening and mature cells). They generally use the same sampling techniques, sample preparation methods and anatomical criteria to separate between differentiation zones and discriminate and count forming xylem cells, resulting in very similar raw data. However, the way these raw data are then processed, producing the elaborated data on which statistical analyses are performed, still remains quite specific to each individual study. Thereby, despite very similar raw data, wood-formation-monitoring studies yield results that are still quite difficult to compare. CAVIAR-an R package specifically dedicated to the verification, visualization and manipulation of wood-formation-monitoring data-can help to improve this situation. Initially, CAVIAR was built to provide efficient algorithms to compute critical dates of wood formation phenology for conifers growing in temperate and cold environments. Recently, we developed it further to check, display and process wood-formation-monitoring data. Thanks to new and upgraded functions, raw data can now be consistently verified, standardized and modelled (using logistic regressions and Gompertz functions), in order to describe wood phenology and intra-annual dynamics of tree-ring formation. We believe that CAVIAR will help strengthening the science of wood formation dynamics by effectively contributing to the standardization of its concepts and

Formation of lacustrine plains in west-central Alaska as a result of permafrost degradation and aggradation

NASA Astrophysics Data System (ADS)

Kanevskiy, M. Z.; Jorgenson, M. T.; Shur, Y.; O'Donnell, J.; Harden, J. W.; Fortier, D.

2012-12-01

Perennially frozen lacustrine sediments containing a large amount of ground ice comprise a significant part of the upper permafrost of the lowlands of west-central Alaska, including Koyukuk Flats and Innoko Flats. Study sites are located in the discontinuous permafrost zone, where permafrost was encountered mainly within uplifted peat plateaus. The upper part of studied sections is formed by frozen peat up to 3 m thick underlain by lacustrine silt, which is mostly ice-rich. Cryogenic structure of lacustrine sediments at different sites has common features: (1) prevalence of layered, braided, and reticulate cryostructures; (2) high variability in the ice content of sediments; (3) high density and low water content of soil aggregates separated by ice lenses. Volume of visible ice in silt reaches at places 40% and more. The thickness of ice lenses generally varies from 1 to 5 cm and occasionally reaches 10 cm. Remnants of peat plateaus are surrounded by unfrozen bogs and fens, formed as a result of thawing and settling of ice-rich lacustrine silt. Modern thermokarst scars initially form at places where ice-rich silt is not protected by a thick layer of organic material. Further development of thermokarst bogs includes lateral enlargement of thaw bulbs and collapsing of the margins of peat plateaus. Lacustrine silt within taliks is covered by woody peat accumulated under forests during the stage of permafrost plateau formation and then by aquatic sphagnum peat accumulated in taliks after collapse. We relate the formation of ice-rich lacustrine sediments to development of lake thermokarst, which affected ice-rich silty yedoma deposits during the transition from Pleistocene to Holocene. Terrain development in lacustrine lowlands of west-central Alaska includes five stages related to permafrost aggradation and degradation from the late Pleistocene to the present time: 1) formation of the ice-rich syngenetic permafrost (yedoma) during the late Pleistocene; 2) yedoma

Recent increases in Arctic freshwater flux affects Labrador Sea convection and Atlantic overturning circulation

NASA Astrophysics Data System (ADS)

Yang, Qian; Dixon, Timothy H.; Myers, Paul G.; Bonin, Jennifer; Chambers, Don; van den Broeke, M. R.

2016-01-01

The Atlantic Meridional Overturning Circulation (AMOC) is an important component of ocean thermohaline circulation. Melting of Greenland's ice sheet is freshening the North Atlantic; however, whether the augmented freshwater flux is disrupting the AMOC is unclear. Dense Labrador Sea Water (LSW), formed by winter cooling of saline North Atlantic water and subsequent convection, is a key component of the deep southward return flow of the AMOC. Although LSW formation recently decreased, it also reached historically high values in the mid-1990s, making the connection to the freshwater flux unclear. Here we derive a new estimate of the recent freshwater flux from Greenland using updated GRACE satellite data, present new flux estimates for heat and salt from the North Atlantic into the Labrador Sea and explain recent variations in LSW formation. We suggest that changes in LSW can be directly linked to recent freshening, and suggest a possible link to AMOC weakening.

Recent increases in Arctic freshwater flux affects Labrador Sea convection and Atlantic overturning circulation

PubMed Central

Yang, Qian; Dixon, Timothy H.; Myers, Paul G.; Bonin, Jennifer; Chambers, Don; van den Broeke, M. R.; Ribergaard, Mads H.; Mortensen, John

2016-01-01

The Atlantic Meridional Overturning Circulation (AMOC) is an important component of ocean thermohaline circulation. Melting of Greenland's ice sheet is freshening the North Atlantic; however, whether the augmented freshwater flux is disrupting the AMOC is unclear. Dense Labrador Sea Water (LSW), formed by winter cooling of saline North Atlantic water and subsequent convection, is a key component of the deep southward return flow of the AMOC. Although LSW formation recently decreased, it also reached historically high values in the mid-1990s, making the connection to the freshwater flux unclear. Here we derive a new estimate of the recent freshwater flux from Greenland using updated GRACE satellite data, present new flux estimates for heat and salt from the North Atlantic into the Labrador Sea and explain recent variations in LSW formation. We suggest that changes in LSW can be directly linked to recent freshening, and suggest a possible link to AMOC weakening. PMID:26796579

Recent increases in Arctic freshwater flux affects Labrador Sea convection and Atlantic overturning circulation.

PubMed

Yang, Qian; Dixon, Timothy H; Myers, Paul G; Bonin, Jennifer; Chambers, Don; van den Broeke, M R

2016-01-22

The Atlantic Meridional Overturning Circulation (AMOC) is an important component of ocean thermohaline circulation. Melting of Greenland's ice sheet is freshening the North Atlantic; however, whether the augmented freshwater flux is disrupting the AMOC is unclear. Dense Labrador Sea Water (LSW), formed by winter cooling of saline North Atlantic water and subsequent convection, is a key component of the deep southward return flow of the AMOC. Although LSW formation recently decreased, it also reached historically high values in the mid-1990s, making the connection to the freshwater flux unclear. Here we derive a new estimate of the recent freshwater flux from Greenland using updated GRACE satellite data, present new flux estimates for heat and salt from the North Atlantic into the Labrador Sea and explain recent variations in LSW formation. We suggest that changes in LSW can be directly linked to recent freshening, and suggest a possible link to AMOC weakening.

Recent progresses on AI-2 bacterial quorum sensing inhibitors.

PubMed

Zhu, Peng; Li, Minyong

2012-01-01

Quorum sensing (QS) is a communication procedure that predominates gene expression in response to cell density and fluctuations in the neighboring environment as a result of discerning molecules termed autoinducers (AIs). It has been embroiled that QS can govern bacterial behaviors such as the secretion of virulence factors, biofilm formation, bioluminescence production, conjugation, sporulation and swarming motility. Autoinducer 2 (AI-2), a QS signaling molecule brought up to be involved in interspecies communication, exists in both gram-negative and -positive bacteria. Therefore, novel approaches to interrupt AI-2 quorum sensing are being recognized as next generation antimicrobials. In the present review article, we summarized recent progresses on AI-2 bacterial quorum sensing inhibitors and discussed their potential as the antibacterial agents.

Elucidating severe urban haze formation in China

NASA Astrophysics Data System (ADS)

Guo, Song; Hu, Min; Zamora, Misti L.; Peng, Jianfei; Shang, Dongjie; Zheng, Jing; Du, Zhuofei; Wu, Zhijun; Shao, Min; Zeng, Limin; Molina, Mario J.; Zhang, Renyi

2014-12-01

As the world's second largest economy, China has experienced severe haze pollution, with fine particulate matter (PM) recently reaching unprecedentedly high levels across many cities, and an understanding of the PM formation mechanism is critical in the development of efficient mediation policies to minimize its regional to global impacts. We demonstrate a periodic cycle of PM episodes in Beijing that is governed by meteorological conditions and characterized by two distinct aerosol formation processes of nucleation and growth, but with a small contribution from primary emissions and regional transport of particles. Nucleation consistently precedes a polluted period, producing a high number concentration of nano-sized particles under clean conditions. Accumulation of the particle mass concentration exceeding several hundred micrograms per cubic meter is accompanied by a continuous size growth from the nucleation-mode particles over multiple days to yield numerous larger particles, distinctive from the aerosol formation typically observed in other regions worldwide. The particle compositions in Beijing, on the other hand, exhibit a similarity to those commonly measured in many global areas, consistent with the chemical constituents dominated by secondary aerosol formation. Our results highlight that regulatory controls of gaseous emissions for volatile organic compounds and nitrogen oxides from local transportation and sulfur dioxide from regional industrial sources represent the key steps to reduce the urban PM level in China.

Elucidating severe urban haze formation in China

PubMed Central

Guo, Song; Hu, Min; Zamora, Misti L.; Peng, Jianfei; Shang, Dongjie; Zheng, Jing; Du, Zhuofei; Wu, Zhijun; Shao, Min; Zeng, Limin; Molina, Mario J.; Zhang, Renyi

2014-01-01

As the world’s second largest economy, China has experienced severe haze pollution, with fine particulate matter (PM) recently reaching unprecedentedly high levels across many cities, and an understanding of the PM formation mechanism is critical in the development of efficient mediation policies to minimize its regional to global impacts. We demonstrate a periodic cycle of PM episodes in Beijing that is governed by meteorological conditions and characterized by two distinct aerosol formation processes of nucleation and growth, but with a small contribution from primary emissions and regional transport of particles. Nucleation consistently precedes a polluted period, producing a high number concentration of nano-sized particles under clean conditions. Accumulation of the particle mass concentration exceeding several hundred micrograms per cubic meter is accompanied by a continuous size growth from the nucleation-mode particles over multiple days to yield numerous larger particles, distinctive from the aerosol formation typically observed in other regions worldwide. The particle compositions in Beijing, on the other hand, exhibit a similarity to those commonly measured in many global areas, consistent with the chemical constituents dominated by secondary aerosol formation. Our results highlight that regulatory controls of gaseous emissions for volatile organic compounds and nitrogen oxides from local transportation and sulfur dioxide from regional industrial sources represent the key steps to reduce the urban PM level in China. PMID:25422462

Connecting Formal and Content Schemata: Some Results of Recent Work in Semiotics.

ERIC Educational Resources Information Center

Oller, John W., Jr.

This paper expands on schematic theory through a review of recent work in the field of semiotics. Content and formal schemata are shown to be grounded respectively in perceptual (abductive) and indexical (inductive) strategies of inference. A third kind of schemata is based on deductive generalization and referred to as abstract schemata. All…

Treatment of collagenase-induced osteoarthritis with a viral vector encoding TSG-6 results in ectopic bone formation.

PubMed

Broeren, Mathijs G A; Di Ceglie, Irene; Bennink, Miranda B; van Lent, Peter L E M; van den Berg, Wim B; Koenders, Marije I; Blaney Davidson, Esmeralda N; van der Kraan, Peter M; van de Loo, Fons A J

2018-01-01

Tumor necrosis factor-inducible gene 6 (TSG-6) has anti-inflammatory and chondroprotective effects in mouse models of inflammatory arthritis. Because cartilage damage and inflammation are also observed in osteoarthritis (OA), we determined the effect of viral overexpression of TSG-6 in experimental osteoarthritis. Bone marrow-derived cells were differentiated to multinucleated osteoclasts in the presence of recombinant TSG-6 or after transduction with a lentiviral TSG-6 expression vector. Multi-nucleated osteoclasts were analyzed after tartrate resistant acid phosphatase staining and resorption activity was determined on dentin slices. Collagenase-induced osteoarthritis (CIOA) was induced in C57BL/6 mice after intra-articular injection of an adenoviral TSG-6 or control luciferase expression vector. Inflammation-related protease activity was measured using bioluminescent Prosense probes. After a second adenovirus injection, cartilage damage was assessed in histological sections stained with Safranin-O. Ectopic bone formation was scored in X-ray images of the affected knees. TSG-6 did not inhibit the formation of multi-nucleated osteoclasts, but caused a significant reduction in the resorption activity on dentin slices. Adenoviral TSG-6 gene therapy in CIOA could not reduce the cartilage damage compared to the luciferase control virus and no significant difference in inflammation-related protease activity was noted between the TSG-6 and control treated group. Instead, X-ray analysis and histological analysis revealed the presence of ectopic bone formation in the TSG-6 treated group. Gene therapy based on the expression of TSG-6 could not provide cartilage protection in experimental osteoarthritis, but instead resulted in increased ectopic bone formation.

On the formation of trappable antihydrogen

NASA Astrophysics Data System (ADS)

Jonsell, S.; Charlton, M.

2018-04-01

The formation of antihydrogen atoms from antiprotons injected into a positron plasma is simulated, focussing on the fraction that fulfil the conditions necessary for confinement of anti-atoms in a magnetic minimum trap. Trapping fractions of around 10‑4 are found under conditions similar to those used in recent experiments, and in reasonable accord with their results. We have studied the behaviour of the trapped fraction at various positron plasma densities and temperatures and found that collisional effects play a beneficial role via a redistribution of the antihydrogen magnetic moment, allowing enhancements of the yield of low-field seeking states that are amenable to trapping.

Oxidants at the Surface of Mars: A Review in Light of Recent Exploration Results

NASA Astrophysics Data System (ADS)

Lasne, J.; Noblet, A.; Szopa, C.; Navarro-González, R.; Cabane, M.; Poch, O.; Stalport, F.; François, P.; Atreya, S. K.; Coll, P.

2016-12-01

In 1976, the Viking landers carried out the most comprehensive search for organics and microbial life in the martian regolith. Their results indicate that Mars' surface is lifeless and, surprisingly, depleted in organics at part-per-billion levels. Several biology experiments on the Viking landers gave controversial results that have since been explained by the presence of oxidizing agents on the surface of Mars. These oxidants may degrade abiotic or biological organics, resulting in their nondetection in the regolith. As several exploration missions currently focus on the detection of organics on Mars (or will do so in the near future), knowledge of the oxidative state of the surface is fundamental. It will allow for determination of the capability of organics to survive on a geological timescale, the most favorable places to seek them, and the best methods to process the samples collected at the surface. With this aim, we review the main oxidants assumed to be present on Mars, their possible formation pathways, and those laboratory studies in which their reactivity with organics under Mars-like conditions has been evaluated. Among the oxidants assumed to be present on Mars, only four have been detected so far: perchlorate ions (ClO4-) in salts, hydrogen peroxide (H2O2) in the atmosphere, and clays and metal oxides composing surface minerals. Clays have been suggested as catalysts for the oxidation of organics but are treated as oxidants in the following to keep the structure of this article straightforward. This work provides an insight into the oxidizing potential of the surface of Mars and an estimate of the stability of organic matter in an oxidizing environment.

Overview of recent experimental results from the Aditya tokamak

NASA Astrophysics Data System (ADS)

Tanna, R. L.; Ghosh, J.; Chattopadhyay, P. K.; Raj, Harshita; Patel, Sharvil; Dhyani, P.; Gupta, C. N.; Jadeja, K. A.; Patel, K. M.; Bhatt, S. B.; Panchal, V. K.; Patel, N. C.; Chavda, Chhaya; Praveenlal, E. V.; Shah, K. S.; Makawana, M. N.; Jha, S. K.; Gopalkrishana, M. V.; Tahiliani, K.; Sangwan, Deepak; Raju, D.; Nagora, Umesh; Pathak, S. K.; Atrey, P. K.; Purohit, S.; Raval, J.; Joisa, Y. S.; Rao, C. V. S.; Chowdhuri, M. B.; Banerjee, S.; Ramaiya, N.; Manchanda, R.; Thomas, J.; Kumar, Ajai; Ajay, Kumar; Sharma, P. K.; Kulkarni, S. V.; Sathyanarayana, K.; Shukla, B. K.; Das, Amita; Jha, R.; Saxena, Y. C.; Sen, A.; Kaw, P. K.; Bora, D.; the ADITYA Team

2017-10-01

Several experiments, related to controlled thermonuclear fusion research and highly relevant for large size tokamaks, including ITER, have been carried out in ADITYA, an ohmically heated circular limiter tokamak. Repeatable plasma discharges of a maximum plasma current of ~160 kA and discharge duration beyond ~250 ms with a plasma current flattop duration of ~140 ms have been obtained for the first time in ADITYA. The reproducibility of the discharge reproducibility has been improved considerably with lithium wall conditioning, and improved plasma discharges are obtained by precisely controlling the position of the plasma. In these discharges, chord-averaged electron density ~3.0-4.0  ×  1019 m-3 using multiple hydrogen gas puffs, with a temperature of the order of ~500-700 eV, have been achieved. Novel experiments related to disruption control are carried out and disruptions, induced by hydrogen gas puffing, are successfully mitigated using the biased electrode and ion cyclotron resonance pulse techniques. Runaway electrons are successfully mitigated by applying a short local vertical field (LVF) pulse. A thorough disruption database has been generated by identifying the different categories of disruption. Detailed analysis of several hundred disrupted discharges showed that the current quench time is inversely proportional to the q edge. Apart from this, for volt-sec recovery during the plasma formation phase, low loop voltage start-up and current ramp-up experiments have been carried out using electron cyclotron resonance heating (ECRH). Successful recovery of volt-sec leads to the achievement of longer plasma discharge durations. In addition, the neon gas puff assisted radiative improved confinement mode has also been achieved in ADITYA. All of the above mentioned experiments will be discussed in this paper.

Correlation of tertiary formations of Alaska

USGS Publications Warehouse

MacNeil, F.S.; Wolfe, J.A.; Miller, D.J.; Hopkins, D.M.

1961-01-01

Recent stratigraphic and paleontologic studies have resulted in substantial revision of the age assignments and inter-basin correlations of the Tertiary formations of Alaska as given in both an earlier compilation by P. S. Smith (1939) and a tentative chart prepared for distribution at the First International Symposium on Arctic Geology at Calgary, Alberta (Miller, MacNeil, and Wahrhaftig, 1960). Current work in Alaska by the U. S. Geological Survey and several oil companies is furnishing new information at a rapid rate and further revisions may be expected. The correlation chart (Fig. 1), the first published chart to deal exclusively with the Tertiary of Alaska, had the benefit of a considerable amount of stratigraphic data and fossil collections from some oil companies, but recent surface mapping and drilling by other oil companies in several Tertiary basins undoubtedly must have produced much more information. Nevertheless, the extent of available data justifies the publication of a revised correlation chart at this time.

The NACA Apparatus for Studying the Formation and Combustion of Fuel Sprays and the Results from Preliminary Tests

NASA Technical Reports Server (NTRS)

Rothrock, A M

1933-01-01

This report describes the apparatus as designed and constructed at the Langley Memorial Aeronautical Laboratory, for studying the formation and combustion of fuel sprays under conditions closely simulating those occurring in a high-speed compression-ignition engine. The apparatus consists of a single-cylinder modified test engine, a fuel-injection system so designed that a single charge of fuel can be injected into the combustion chamber of the engine, an electric driving motor, and a high-speed photographic apparatus. The cylinder head of the engine has a vertical-disk form of combustion chamber whose sides are glass windows. When the fuel is injected into the combustion chamber, motion pictures at the rate of 2,000 per second are taken of the spray formation by means of spark discharges. When combustion takes place the light of the combustion is recorded on the same photographic film as the spray photographs. The report includes the results of some tests to determine the effect of air temperature, air flow, and nozzle design on the spray formation.

Recent results from the sudbury neutrino observatory

DOE PAGES

Poon, A. W.

2003-12-17

The Sudbury Neutrino Observatory (SNO) measures both the flux of the electron-type neutrinos and the total flux of all active flavours of neutrinos originating from the Sun. A model-independent test of neutrino flavour transformation was performed by comparing these two measurements. In 2002, this flavour transformation was definitively demonstrated. In this talk, results from these measurements and the current status of the SNO detector are presented.

Recent Advances in Chiral Nematic Structure and Iridescent Color of Cellulose Nanocrystal Films

PubMed Central

Gray, Derek G.

2016-01-01

One unique property of cellulose nanocrystals (CNC) is their property of forming suspensions with chiral nematic order. This order can be preserved in films cast from the suspensions, raising the possibility of applications as photonic materials and templates. However, it has proved difficult to generate uniform, well-ordered chiral nematic materials from CNC. Recently, the importance of kinetic arrest due to gel formation in the later stages of evaporation has been recognized as a key step in film formation. In this brief review, recent developments regarding the structure of chiral nematic suspensions and films as monitored by polarized light microscopy are outlined, and attention is drawn to the importance of shear forces on the self-organization process. PMID:28335340

Presolar stardust in meteorites: recent advances and scientific frontiers

NASA Astrophysics Data System (ADS)

Nittler, Larry R.

2003-04-01

Grains of stardust that formed in stellar outflows prior to the formation of the solar system survive intact as trace constituents of primitive meteorites. The presolar origin of the grains is indicated by enormous isotopic ratio variations compared to solar system materials. Identified presolar phases include diamond, silicon carbide, graphite, silicon nitride, corundum, spinel, hibonite, titanium oxide, and, most recently, silicates. Sub-grains of refractory carbides (e.g. TiC), and Fe-Ni metal have also been observed within individual presolar graphite grains. Isotopic compositions indicate that the grains formed in red giants, asymptotic giant branch (AGB) stars, supernovae and novae; thus they provide unique insights into the evolution of and nucleosynthesis within these environments. Some of the isotopic variations also reflect the chemical evolution of the galaxy and can be used to constrain corresponding models. Presolar grain microstructures provide information about physical and chemical conditions of dust formation in stellar environments; recent studies have focused on graphite grains from supernovae as well as SiC and corundum from AGB stars. The survival of presolar grains in different classes of meteorites has important implications for early solar system evolution. Recent analytical developments, including resonance ionization mass spectrometry, high spatial resolution secondary ion mass spectrometry and site-selective ion milling, should help solve many outstanding problems but are likely to also introduce new surprises.

Recent Performance Results of VPIC on Trinity

NASA Astrophysics Data System (ADS)

Nystrom, W. D.; Bergen, B.; Bird, R. F.; Bowers, K. J.; Daughton, W. S.; Guo, F.; Le, A.; Li, H.; Nam, H.; Pang, X.; Stark, D. J.; Rust, W. N., III; Yin, L.; Albright, B. J.

2017-10-01

Trinity is a new DOE compute resource now in production at Los Alamos National Laboratory. Trinity has several new and unique features including two compute partitions, one with dual socket Intel Haswell Xeon compute nodes and one with Intel Knights Landing (KNL) Xeon Phi compute nodes, use of on package high bandwidth memory (HBM) for KNL nodes, ability to configure KNL nodes with respect to HBM model and on die network topology in a variety of operational modes at run time, and use of solid state storage via burst buffer technology to reduce time required to perform I/O. An effort is in progress to optimize VPIC on Trinity by taking advantage of these new architectural features. Results of work will be presented on performance of VPIC on Haswell and KNL partitions for single node runs and runs at scale. Results include use of burst buffers at scale to optimize I/O, comparison of strategies for using MPI and threads, performance benefits using HBM and effectiveness of using intrinsics for vectorization. Work performed under auspices of U.S. Dept. of Energy by Los Alamos National Security, LLC Los Alamos National Laboratory under contract DE-AC52-06NA25396 and supported by LANL LDRD program.

Incorporation of recent waking-life experiences in dreams correlates with frontal theta activity in REM sleep.

PubMed

Eichenlaub, Jean-Baptiste; van Rijn, Elaine; Gareth Gaskell, M; Lewis, Penelope A; Maby, Emmanuel; Malinowski, Josie; Walker, Matthew P; Boy, Frederic; Blagrove, Mark

2018-06-04

Rapid Eye Movement (REM) sleep and its main oscillatory feature, frontal theta, have been related to the processing of recent emotional memories. As memories constitute much of the source material for our dreams, we explored the link between REM frontal theta and the memory sources of dreaming, so as to elucidate the brain activities behind the formation of dream content. Twenty participants were woken for dream reports in REM and Slow Wave Sleep (SWS) while monitored using electroencephalography. Eighteen participants reported at least one REM dream and 14 at least one SWS dream, and they, and independent judges, subsequently compared their dream reports with log records of their previous daily experiences. The number of references to recent waking-life experiences in REM dreams was positively correlated with frontal theta activity in the REM sleep period. No such correlation was observed for older memories, nor for SWS dreams. The emotional intensity of recent waking-life experiences incorporated into dreams was higher than the emotional intensity of experiences that were not incorporated. These results suggest that the formation of wakefulness-related dream content is associated with REM theta activity, and accords with theories that dreaming reflects emotional memory processing taking place in REM sleep.

Bacterial ethane formation from reduced, ethylated sulfur compounds in anoxic sediments

USGS Publications Warehouse

Oremland, R.S.; Whiticar, Michael J.; Strohmaier, F.E.; Kiene, R.P.

1988-01-01

Trace levels of ethane were produced biologically in anoxic sediment slurries from five chemically different aquatic environments. Gases from these locations displayed biogenic characteristics, having 12C-enriched values of ??13CH4 (-62 to -86%.), ??13C2H6 (-35 to -55%.) and high ratios (720 to 140,000) of CH4 [C2H6 + C3H8]. Endogenous production of ethane by slurries was inhibited by autoclaving or by addition of the inhibitor of methanogenic bacteria, 2-bromoethanesulfonic acid (BES). Ethane formation was stimulated markedly by ethanethiol (ESH), and, to a lesser extent, by diethylsulfide (DES). Formation of methane and ethane in ESH- or DES-amended slurries was blocked by BES. Experiments showed that ethionine (or an analogous compound) could be a precursor of ESH. Ethylamine or ethanol additions to slurries caused only a minor stimulation of ethane formation. Similarly, propanethiol additions resulted in only a minor enhancement of propane formation. Cell suspensions of a methyltrophic methanogen produced traces of ethane when incubated in the presence of DES, although the organism did not grow on this compound. These results indicate that methanogenic bacteria produce ethane from the traces of ethylated sulfur compounds present in recent sediments. Preliminary estimates of stable carbon isotope fractionation associated with sediment methane formation from dimethylsulfide was about 40%., while ethane formation from DES and ESH was only 4. 6 and 6.5%., respectively. ?? 1988.

Ice Cloud Formation and Dehydration in the Tropical Tropopause Layer

NASA Technical Reports Server (NTRS)

Jensen, Eric; Pfister, Leonhard; Gore, Warren J. (Technical Monitor)

2002-01-01

Stratospheric water vapor is important not only for its greenhouse forcing, but also because it plays a significant role in stratospheric chemistry. several recent studies have focused on the potential for dehydration due to ice cloud formation in air rising slowly through the tropical tropopause layer. Holton and Gettelman showed that temperature variations associated with horizontal transport of air in the tropopause layer can drive ice cloud formation and dehydration, and Gettelman et al. recently examined the cloud formation and dehydration along kinematic trajectories using simple assumptions about the cloud properties. In this study, we use a Lagrangian, one-dimensional cloud model to further investigate cloud formation and dehydration as air is transported horizontally and vertically through the tropical tropopause layer. Time-height curtains of temperature are extracted from meteorological analyses. The model tracks the growth and sedimentation of individual cloud particles. The regional distribution of clouds simulated in the model is comparable to the subvisible cirrus distribution indicated by SAGE II. The simulated cloud properties depend strongly on the assumed ice supersaturation threshold for ice nucleation. with effective nuclei present (low supersaturation threshold), ice number densities are high (0.1--10 cm(circumflex)-3), and ice crystals do not grow large enough to fall very far, resulting in limited dehydration. With higher supersaturation thresholds, ice number densities are much lower (less than 0.01 cm(circumflex)-3), and ice crystals grow large enough to fall substantially; however, supersaturated air often crosses the tropopause without cloud formation. The clouds typically do not dehydrate the air along trajectories down to the temperature minimum saturation mixing ratio. Rather the water vapor mixing ratio crossing the tropopause along trajectories is typically 10-50% larger than the saturation mixing ratio.

Neoendemism in Madagascan scaly tree ferns results from recent, coincident diversification bursts.

PubMed

Janssen, Thomas; Bystriakova, Nadia; Rakotondrainibe, France; Coomes, David; Labat, Jean-Noël; Schneider, Harald

2008-08-01

More than 80% of Madagascar's 12,000 plant species are endemic with the degree of endemism reaching as much as 95% in the scaly tree ferns, an important species rich component of Madagascar's evergreen rainforests. Predominantly African or Asian ancestry and divergence times usually postdating the separation of Madagascar from the Gondwanan landmasses have been demonstrated for several Madagascan animal and angiosperm groups. However, evolutionary studies of rainforest-specific lineages are scarce and the ecological context of radiation events has rarely been investigated. Here, we examine the evolution of Madagascan tree ferns as a rainforest-specific model family, integrate results from bioclimatic niche analysis with a dated phylogenetic framework, and propose an evolutionary scenario casting new light on our knowledge of the evolution of large island endemic clades. We show that Madagascar's extant tree fern diversity springs from three distinct ancestors independently colonizing Madagascar in the Miocene and that these three monophyletic clades diversified in three coincident radiation bursts during the Pliocene, reaching exceptionally high diversification rates and most likely responding to a common climatic trigger. Recent diversification bursts may thus have played a major role in the evolution of the extant Madagascan rainforest biome, which hence contains a significant number of young, neoendemic taxa.

Cosmological structure formation

NASA Technical Reports Server (NTRS)

Schramm, David N.

1991-01-01

A summary of the current forefront problem of physical cosmology, the formation of structures (galaxies, clusters, great walls, etc.) in the universe is presented. Solutions require two key ingredients: (1) matter; and (2) seeds. Regarding the matter, it now seems clear that both baryonic and non-baryonic matter are required. Whether the non-baryonic matter is hot or cold depends on the choice of seeds. Regarding the seeds, both density fluctuations and topological defects are discussed. The combination of isotropy of the microwave background and the recent observations indicating more power on large scales have severly constrained, if not eliminated, Gaussian fluctuations with equal power on all scales, regardless of the eventual resolution of both the matter and seed questions. It is important to note that all current structure formation ideas require new physics beyond SU(3) x SU(2) x U(1).

Recent Ocean Literacy Research in United States Public Schools: Results and Implications

ERIC Educational Resources Information Center

Plankis, Brian J.; Marrero, Meghan E.

2010-01-01

Recent research conducted on adults in the United States indicates low ocean literacy (Ocean Project, 2009b, 1999), but there is a dearth of peer-reviewed research on K-12 students' ocean literacy. This paper presents two research studies that examined the ocean and environmental literacy of 464 K-12 students in five states. Like the majority of…

GERDA: Recent results and future plans

NASA Astrophysics Data System (ADS)

Lehnert, Björn

2014-04-01

The GERmanium Detector Array (GERDA) is an experiment designed to investigate the neutrinoless double beta decay (0 νββ) in 76Ge. An array of high purity germanium detectors isotopically enriched to 87% of 76Ge is operated within 64 m3 of liquid argon (LAr) at the Laboratori Nazionali del Gran Sasso (LNGS). The experiment aims to explore the 0 νββ half-life up to 1.4×1026 yr with a collected exposure of 100 kg yr separated into two physics phases. The data taking of Phase I started in November 2011 and finished in May 2013 with 21.6 kg yr of exposure and a background index (BI) of 2×10-2cts/(kg yr keV) around the Q-value of 2039 keV before pulse shape cuts. Phase II of the experiment is being prepared with additional 30 Broad Energy Germanium (BEGe) detectors and an instrumentation of the LAr, aiming at a BI reduction by a factor of 10 w.r. to Phase I. This paper will present the GERDA setup and the latest results of the experiment including a new measurement of the 2 νββ spectrum of 76Ge and the decomposition of the background spectrum. The 0 νββ analysis, finished in the meanwhile, will be briefly mentioned. Furthermore, the major improvements planned for Phase II will be discussed.

Recent formation of arroyos in the Little Missouri Badlands of southwestern North Dakota

USGS Publications Warehouse

Gonzalez, M.A.

2001-01-01

In the Little Missouri Badlands of southwestern North Dakota, the channels of ephemeral streams are incised 2 to 10 m or more into mid-to-late Holocene alluvium. The objectives of this study were to determine the timing and cause(s) of the most recent episodes of fluvial incision and to develop a process-response model that illustrates the formation and evolution of arroyos in this region. The purpose was to distinguish natural from anthropogenic changes to the landscape and to discriminate allogenic from autogenic causes of incision, thereby gaining a greater sense of how steep, relatively small, ephemeral streams evolve. Dendrochronologic and dendrogeomorphic analyses of riparian cottonwoods provide an inexpensive, high-resolution dating method to constrain the time of incision, thereby permitting determination of the cause(s) of incision by evaluating environmental conditions prior to and at the onset of fluvial incision. An examination of seven small (10 to 100 km2) drainage basins indicated ephemeral streams have undergone a four-stage cycle of change within the past 200 years, comprising(i) an initial period of relative geomorphic stability with pedogenesis on the flood plain and low rates of lateral channel migration, (ii) a period of channel incision with subsequent widening of the flood plain through lateral corrasion along middle and upstream reaches, (iii) a concomitant period of aggradation along downstream reaches and, finally, (iv) a period of downstream incision. Dendrochronologic data and dendrogeomorphic relations indicate there have been three distinct periods of fluvial incision in the past 200 years. The first period of incision began in the 1860s and 1870s prior to the onset of European settlement and intensive grazing by domesticated cattle in the area. This period of incision occurred along the middle reaches of all seven of the streams examined and coincided with a severe, protracted drought, suggesting an allogenic cause. The second period

Environmental factors that shape biofilm formation.

PubMed

Toyofuku, Masanori; Inaba, Tomohiro; Kiyokawa, Tatsunori; Obana, Nozomu; Yawata, Yutaka; Nomura, Nobuhiko

2016-01-01

Cells respond to the environment and alter gene expression. Recent studies have revealed the social aspects of bacterial life, such as biofilm formation. Biofilm formation is largely affected by the environment, and the mechanisms by which the gene expression of individual cells affects biofilm development have attracted interest. Environmental factors determine the cell's decision to form or leave a biofilm. In addition, the biofilm structure largely depends on the environment, implying that biofilms are shaped to adapt to local conditions. Second messengers such as cAMP and c-di-GMP are key factors that link environmental factors with gene regulation. Cell-to-cell communication is also an important factor in shaping the biofilm. In this short review, we will introduce the basics of biofilm formation and further discuss environmental factors that shape biofilm formation. Finally, the state-of-the-art tools that allow us investigate biofilms under various conditions are discussed.

PLANETESIMAL FORMATION IN MAGNETOROTATIONALLY DEAD ZONES: CRITICAL DEPENDENCE ON THE NET VERTICAL MAGNETIC FLUX

DOE Office of Scientific and Technical Information (OSTI.GOV)

Okuzumi, Satoshi; Hirose, Shigenobu, E-mail: okuzumi@nagoya-u.jp

Turbulence driven by magnetorotational instability (MRI) affects planetesimal formation by inducing diffusion and collisional fragmentation of dust particles. We examine conditions preferred for planetesimal formation in MRI-inactive 'dead zones' using an analytic dead-zone model based on our recent resistive MHD simulations. We argue that successful planetesimal formation requires not only a sufficiently large dead zone (which can be produced by tiny dust grains) but also a sufficiently small net vertical magnetic flux (NVF). Although often ignored, the latter condition is indeed important since the NVF strength determines the saturation level of turbulence in MRI-active layers. We show that direct collisionalmore » formation of icy planetesimal across the fragmentation barrier is possible when the NVF strength is lower than 10 mG (for the minimum-mass solar nebula model). Formation of rocky planetesimals via the secular gravitational instability is also possible within a similar range of the NVF strength. Our results indicate that the fate of planet formation largely depends on how the NVF is radially transported in the initial disk formation and subsequent disk accretion processes.« less

A GAS-PHASE FORMATION ROUTE TO INTERSTELLAR TRANS-METHYL FORMATE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cole, Callie A.; Wehres, Nadine; Yang Zhibo

2012-07-20

The abundance of methyl formate in the interstellar medium has previously been underpredicted by chemical models. Additionally, grain surface chemistry cannot account for the relative abundance of the cis- and trans-conformers of methyl formate, and the trans-conformer is not even formed at detectable abundance on these surfaces. This highlights the importance of studying formation pathways to methyl formate in the gas phase. The rate constant and branching fractions are reported for the gas-phase reaction between protonated methanol and formic acid to form protonated trans-methyl formate and water as well as adduct ion: Rate constants were experimentally determined using a flowingmore » afterglow-selected ion flow tube apparatus at 300 K and a pressure of 530 mTorr helium. The results indicate a moderate overall rate constant of (3.19 {+-} 0.39) Multiplication-Sign 10{sup -10} cm{sup 3} s{sup -1} ({+-} 1{sigma}) and an average branching fraction of 0.05 {+-} 0.04 for protonated trans-methyl formate and 0.95 {+-} 0.04 for the adduct ion. These experimental results are reinforced by ab initio calculations at the MP2(full)/aug-cc-pVTZ level of theory to examine the reaction coordinate and complement previous density functional theory calculations. This study underscores the need for continued observational studies of trans-methyl formate and for the exploration of other gas-phase formation routes to complex organic molecules.« less

Ultracompact Blue Dwarfs: Galaxy Formation in the Local Universe?

NASA Astrophysics Data System (ADS)

Corbin, Michael

2004-07-01

Recent observations suggest that very low-mass galaxies in the local universe are still in the process of formation. To investigate this issue we propose to obtain deep ACS HRC images in the U, V and I bands of a sample of 11 "ultracompact" blue dwarf galaxies {UCBDs} identified in the Sloan Digital Sky Survey. These objects are nearby {z < 0.009}, actively star-forming, and have extremely small angular and physical sizes {d < 6" and D < 1 kpc}. They also tend to reside in voids. Our WFPC2 images of the prototype object of this class, POX 186, reveal this tiny object to have a highly disturbed morphlogy indicative of a recent {within 10^8 yr} collision between two small { 100 pc} clumps of stars that could represent the long-sought building blocks predicted by the Press-Schechter model of hierarchical galaxy formation. This collision has also triggered the formation of a "super" star cluster {SSC} at the object's core that may be the progenitor of a globular cluster. POX 186 thus appears to be a very small dwarf galaxy in the process of formation. This exciting discovery strongly motivates HST imaging of a full sample of UCBDs in order to determine if they have morphologies similar to POX 186. HST images are essential for resolving the structure of these objects, including establishing the presence of SSCs. HST also offers the only way to determine their morphologies in the near UV. The spectra of the objects available from the SDSS will also allow us to measure their star formation rates, dust content and metallicities. In addition to potentially providing the first direct evidence of Press-Schechter building blocks, these data could yield insight into the relationship between galaxy and globular cluster formation, and will serve as a test of the recent "downsizing" model of galaxy formation in which the least massive objects are the last to form.

Oxidation flow reactors (OFRs): overview of recent field and modeling studies

NASA Astrophysics Data System (ADS)

Jimenez, Jose-Luis; Palm, Brett B.; Peng, Zhe; Hu, Weiwei; Ortega, Amber M.; Li, Rui; Campuzano-Jost, Pedro; Day, Douglas A.; Stark, Harald; Brune, William H.; de Gouw, Joost; Schroder, Jason

2016-04-01

Oxidation flow reactors (OFRs) are popular tools for studying SOA formation and aging in both laboratory and field experiments. In an OFR, the concentration of an oxidant (OH, O3, or NO3) can be increased, leading to hours-months of equivalent atmospheric oxidation during the several-minute OFR residence time. Using gas- and particle-phase measurements from several recent field campaigns, we demonstrate SOA formation after oxidation of ambient air in an OFR. Typically, more SOA formation is observed from nighttime air than daytime air. This indicates that the concentration of SOA-forming gases in ambient air is relatively higher at night. Measured ambient VOCs are not able to explain the magnitude of SOA formation in the OFR, suggesting that typically unmeasured S/IVOCs (possibly VOC oxidation products or direct emissions) play a substantial intermediary role in ambient SOA formation. We also present highlights from recent OFR oxidant chemistry modeling studies. HOx, Ox, and photolysis chemistry was modeled for two common OH production methods (utilizing 185+254 nm UV light, or 254 nm only). OH exposure (OHexp) can be estimated within a factor of ~2 using model-derived equations, and can be verified in situ using VOC decay measurements. OHexp is strongly dependent on external OH reactivity, which may cause significant OH suppression in some circumstances (e.g., lab/source studies with high precursor concentrations). UV light photolysis and reaction with oxygen atoms are typically not major reaction pathways. Modeling the fate of condensable low-volatility organic gases (LVOCs) formed in an OFR suggests that LVOC fate is dependent on particle condensational sink. E.g., for the range of particle condensational sink at a remote pine forest, anywhere from 20-80% of produced LVOCs were predicted to condense onto aerosols for an OHexp of ~1 day, with the remainder lost to OFR or sampling line walls. Similar to large chamber wall loss corrections, a correction is needed

Role of Alloying Additions in Glass Formation and Properties of Bulk Metallic Glasses

PubMed Central

Chen, Na; Martin, Laura; Luzguine-Luzgin, Dmitri V.; Inoue, Akihisa

2010-01-01

Alloying addition, as a means of improving mechanical properties and saving on costs of materials, has been applied to a broad range of uses and products in the metallurgical fields. In the field of bulk metallic glasses (BMGs), alloying additions have also proven to play effective and important roles in promoting glass formation, enhancing thermal stability and improving plasticity of the materials. Here, we review the work on the role of alloying additions in glass formation and performance improvement of BMGs, with focus on our recent results of alloying additions in Pd-based BMGs. PMID:28883386

Rebamipide, an Amino Acid Analog of 2(1H)-Quinolinone, Inhibits the Formation of Human Osteoclasts

PubMed Central

Kobashigawa, Tsuyoshi

2016-01-01

Objectives. Drug repositioning or drug reprofiling (DR) has recently been growing in importance. DR has a significant advantage over traditional drug development because the repositioned drug has already passed toxicity tests; its safety is known, and the risk of adverse toxicology is reduced. In the current study, we investigated the role of rebamipide, a mucosa-protecting agent, with recently reported anti-inflammatory function, in human osteoclastogenesis. Methods. Peripheral blood mononuclear cells (PBMCs) were cultured in the presence of M-CSF and sRANKL. Osteoclast formation was evaluated by immunohistological staining for CD51/61 (vitronectin receptors). Osteoclast formation, in the presence or absence of rebamipide (0, 1, and 3 mM), was observed by time-lapse photography and actin ring formation. The number of absorption sites and area of absorption were calculated using Osteologic™ plates. Pit formation was studied by 3D-SEM. Results. Rebamipide inhibited human osteoclast formation at 3 mM, a pharmacological concentration, and inhibited resorbing activity dose-dependently. Rebamipide induced the degradation of actin rings in mature osteoclasts. This mechanism may involve inhibiting the osteoclast fusion pathway through reducing the expression of DC-specific transmembrane protein (DC-STAMP). Conclusions. The present study suggests that rebamipide would be useful as a novel agent for osteoporosis and rheumatoid arthritis. PMID:27965978

Rebamipide, an Amino Acid Analog of 2(1H)-Quinolinone, Inhibits the Formation of Human Osteoclasts.

PubMed

Nanke, Yuki; Kobashigawa, Tsuyoshi; Yago, Toru; Kawamoto, Manabu; Yamanaka, Hisashi; Kotake, Shigeru

2016-01-01

Objectives . Drug repositioning or drug reprofiling (DR) has recently been growing in importance. DR has a significant advantage over traditional drug development because the repositioned drug has already passed toxicity tests; its safety is known, and the risk of adverse toxicology is reduced. In the current study, we investigated the role of rebamipide, a mucosa-protecting agent, with recently reported anti-inflammatory function, in human osteoclastogenesis. Methods. Peripheral blood mononuclear cells (PBMCs) were cultured in the presence of M-CSF and sRANKL. Osteoclast formation was evaluated by immunohistological staining for CD51/61 (vitronectin receptors). Osteoclast formation, in the presence or absence of rebamipide (0, 1, and 3 mM), was observed by time-lapse photography and actin ring formation. The number of absorption sites and area of absorption were calculated using Osteologic™ plates. Pit formation was studied by 3D-SEM. Results . Rebamipide inhibited human osteoclast formation at 3 mM, a pharmacological concentration, and inhibited resorbing activity dose-dependently. Rebamipide induced the degradation of actin rings in mature osteoclasts. This mechanism may involve inhibiting the osteoclast fusion pathway through reducing the expression of DC-specific transmembrane protein (DC-STAMP). Conclusions . The present study suggests that rebamipide would be useful as a novel agent for osteoporosis and rheumatoid arthritis.

Volume nanograting formation in laser-silica interaction as a result of the 1D plasma-resonance ionization instability

NASA Astrophysics Data System (ADS)

Gildenburg, V. B.; Pavlichenko, I. A.

2016-08-01

The initial stage of the small-scale ionization-induced instability developing inside the fused silica volume exposed to the femtosecond laser pulse is studied as a possible initial cause of the self-organized nanograting formation. We have calculated the spatial spectra of the instability with the electron-hole diffusion taken into account for the first time and have found that it results in the formation of some hybrid (diffusion-wave) 1D structure with the spatial period determined as the geometrical mean of the laser wavelength and characteristic diffusion length of the process considered. Near the threshold of the instability, this period occurs to be approximately equal to the laser half-wavelength in the silica, close to the one experimentally observed.

Volume nanograting formation in laser-silica interaction as a result of the 1D plasma-resonance ionization instability

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gildenburg, V. B., E-mail: gil@appl.sci-nnov.ru; Pavlichenko, I. A.; Institute of Applied Physics, Russian Academy of Sciences, Nizhny Novgorod 603950

2016-08-15

The initial stage of the small-scale ionization-induced instability developing inside the fused silica volume exposed to the femtosecond laser pulse is studied as a possible initial cause of the self-organized nanograting formation. We have calculated the spatial spectra of the instability with the electron-hole diffusion taken into account for the first time and have found that it results in the formation of some hybrid (diffusion-wave) 1D structure with the spatial period determined as the geometrical mean of the laser wavelength and characteristic diffusion length of the process considered. Near the threshold of the instability, this period occurs to be approximatelymore » equal to the laser half-wavelength in the silica, close to the one experimentally observed.« less

Recent results concerning the stability of viscoelastic shear deformable plates under compressive edge loading

NASA Technical Reports Server (NTRS)

Librescu, L.; Chandiramani, N. K.

1989-01-01

Some recent results obtained by the authors are summarized concerning the stability of transversely isotropic flat panels whose materials exhibit a viscoelastic behavior and whose edges are subjected to in-plane biaxial compressive loads. Two transversely isotropic type materials, largely used in advanced technology, are considered: (1) the pyrolytic-graphite type, used in the thermal protection of aerospace vehicles, and (2) the type corresponding to unidirectional fiber-reinforced composites. In the former case, the planes of isotropy are parallel at each point to the midplane of the plate. In the latter case, they are normal to the fiber directions. The micromechanical relations developed by Aboudi (1984, 1986, 1987) are considered in conjunction with the correspondence principle of linear viscoelastic theory in order to predict the macroscopic viscoelastic properties of a material composed of uniaxial elastic fibers embedded in a linear viscoelastic matrix.

Scaffold-free Tissue Formation Under Real and Simulated Microgravity Conditions.

PubMed

Aleshcheva, Ganna; Bauer, Johann; Hemmersbach, Ruth; Slumstrup, Lasse; Wehland, Markus; Infanger, Manfred; Grimm, Daniela

2016-10-01

Scaffold-free tissue formation in microgravity is a new method in regenerative medicine and an important topic in Space Medicine. In this MiniReview, we focus on recent findings in the field of tissue engineering that were observed by exposing cells to real microgravity in space or to devices simulating to at least some extent microgravity conditions on Earth (ground-based facilities). Under both conditions - real and simulated microgravity - a part of the cultured cells of various populations detaches from the bottom of a culture flask. The cells form three-dimensional (3D) aggregates resembling the organs from which the cells have been derived. As spaceflights are rare and extremely expensive, cell culture under simulated microgravity allows more comprehensive and frequent studies on the scaffold-free 3D tissue formation in some aspects, as a number of publications have proven during the last two decades. In this MiniReview, we summarize data from our own studies and work from various researchers about tissue engineering of multi-cellular spheroids formed by cancer cells, tube formation by endothelial cells and cartilage formation by exposing the cells to ground-based facilities such as the 3D Random Positioning Machine (RPM), the 2D Fast-Rotating Clinostat (FRC) or the Rotating Wall Vessel (RWV). Subsequently, we investigated self-organization of 3D aggregates without scaffolds pursuing to enhance the frequency of 3D formation and to enlarge the size of the organ-like aggregates. The density of the monolayer exposed to real or simulated microgravity as well as the composition of the culture media revealed an impact on the results. Genomic and proteomic alterations were induced by simulated microgravity. Under microgravity conditions, adherent cells expressed other genes than cells grown in spheroids. In this MiniReview, the recent improvements in scaffold-free tissue formation are summarized and relationships between phenotypic and molecular appearance are

Oxidants at the Surface of Mars: A Review in Light of Recent Exploration Results.

PubMed

Lasne, J; Noblet, A; Szopa, C; Navarro-González, R; Cabane, M; Poch, O; Stalport, F; François, P; Atreya, S K; Coll, P

2016-12-01

In 1976, the Viking landers carried out the most comprehensive search for organics and microbial life in the martian regolith. Their results indicate that Mars' surface is lifeless and, surprisingly, depleted in organics at part-per-billion levels. Several biology experiments on the Viking landers gave controversial results that have since been explained by the presence of oxidizing agents on the surface of Mars. These oxidants may degrade abiotic or biological organics, resulting in their nondetection in the regolith. As several exploration missions currently focus on the detection of organics on Mars (or will do so in the near future), knowledge of the oxidative state of the surface is fundamental. It will allow for determination of the capability of organics to survive on a geological timescale, the most favorable places to seek them, and the best methods to process the samples collected at the surface. With this aim, we review the main oxidants assumed to be present on Mars, their possible formation pathways, and those laboratory studies in which their reactivity with organics under Mars-like conditions has been evaluated. Among the oxidants assumed to be present on Mars, only four have been detected so far: perchlorate ions (ClO 4 - ) in salts, hydrogen peroxide (H 2 O 2 ) in the atmosphere, and clays and metal oxides composing surface minerals. Clays have been suggested as catalysts for the oxidation of organics but are treated as oxidants in the following to keep the structure of this article straightforward. This work provides an insight into the oxidizing potential of the surface of Mars and an estimate of the stability of organic matter in an oxidizing environment. Key Words: Mars surface-Astrobiology-Oxidant-Chemical reactions. Astrobiology 16, 977-996.

Results from Archive Data From SMART-1 Combined with Recent Missions

NASA Astrophysics Data System (ADS)

Foing, Bernard

2013-04-01

We highlight new results from combined data analysis using SMART-1 archive with data from other recent lunar missions. We concentrate on results obtained on the lunar farside, the poles and about the coupling between impact, volcanic and tectonic processes. SMART-1 demonstrated the use of Solar Electric Propulsion for deep space, tested new technologies for spacecraft and instruments miniaturisation, and provided an opportunity for science [1-24] until impact on 3 September 2006. To date, 77 refereed papers and more than 330 conference or technical papers have been published based on SMART-1 (see ADS on SMART-1 scitech website). The SMART-1 data are accessible on the ESA Planetary Science Archive PSA [13]. The lunar North and South polar illumination was mapped and monitored over the entire year, permitting to identify "SMART-1 peaks of quasi-eternal light", then charcterised with subsequent missions. The surface mineralogy maps of the central and northern parts of the South-Pole Aitken basin, was based on Clementine and SMART-1 AMIE images for additional geomorphological and stratigraphic information. [1] Foing etal (2001) EMP 85-523 [2] Racca et al (2002) EMP 85-379 [3] Racca et al. (2002) PSS 50-1323 [4] Grande et al. (2003) PSS 51-427 [5] Dunkin et al. (2003) PSS 51-435 [6] Huovelin et al. (2002) PSS 50-1345 [7] Shkuratov et al (2003) JGRE 108-E4-1 [8] Foing et al (2003) ASR 31-2323 [9] Grande et al (2007) PSS 55-494 [10] Pinet et al (2005) PSS 53-1309 [11] Josset etal (2006) ASR 37-14 [12] Foing et al (2006) ASR 37-6 [13] Heather et al, EPSC-DPS 2011-873 [13b] http://www.rssd.esa.int/psa [14] Muinonen et al (2011) A&A531-150 [15] Souchon et al EPSC-DPS 2011-928 [16] Grieger (2010) cosp 38-417 [17] Bussey et al (2011) LPICO-1621-5 [18] Pluchino et al MSAItS 16-152 [19] Qiao (2011) AcASn 52, 539 [20] Vaananen et al (2009) SolarPhys 260-479 [21] Alha et al (2012)NIMPA 664, 358 [22] Bhattacharya et al EPSC-DPS 2011-1842 [23] Burchell et al (2010) Icarus207-28 [24

Expression of Fap amyloids in Pseudomonas aeruginosa, P. fluorescens, and P. putida results in aggregation and increased biofilm formation

PubMed Central

Dueholm, Morten S; Søndergaard, Mads T; Nilsson, Martin; Christiansen, Gunna; Stensballe, Allan; Overgaard, Michael T; Givskov, Michael; Tolker-Nielsen, Tim; Otzen, Daniel E; Nielsen, Per H

2013-01-01

The fap operon, encoding functional amyloids in Pseudomonas (Fap), is present in most pseudomonads, but so far the expression and importance for biofilm formation has only been investigated for P. fluorescens strain UK4. In this study, we demonstrate the capacity of P. aeruginosa PAO1, P. fluorescens Pf-5, and P. putida F1 to express Fap fibrils, and investigated the effect of Fap expression on aggregation and biofilm formation. The fap operon in all three Pseudomonas species conferred the ability to express Fap fibrils as shown using a recombinant approach. This Fap overexpression consistently resulted in highly aggregative phenotypes and in increased biofilm formation. Detailed biophysical investigations of purified fibrils confirmed FapC as the main fibril monomer and supported the role of FapB as a minor, nucleating constituent as also indicated by bioinformatic analysis. Bioinformatics analysis suggested FapF and FapD as a potential β-barrel membrane pore and protease, respectively. Manipulation of the fap operon showed that FapA affects monomer composition of the final amyloid fibril, and that FapB is an amyloid protein, probably a nucleator for FapC polymerization. Our study highlights the fap operon as a molecular machine for functional amyloid formation. PMID:23504942

Investigating Type I Polar Stratospheric Cloud Formation Mechanisms with POAM Satellite Observations

NASA Technical Reports Server (NTRS)

Strawa, Anthony W.; Drdla, K.; Fromm, M.; Hoppel, K.; Browell, E.; Hamill, P.; Dempsey, D.; Gore, Warren J. (Technical Monitor)

2001-01-01

Type Ia PSCs are believed to be composed of nitric acid hydrate particles. Recent results from the SOLVE/THESEO 2000 campaign showed evidence that this type of PSC was composed of a small number of very large particles capable of sedimentary denitrification of regions of the stratosphere. It is unknown whether homogeneous or heterogeneous nucleation is responsible for the formation of these PSCs. Arctic winters are tending to be colder in response to global tropospheric warming. The degree to which this influences ozone depletion will depend on the freezing mechanism of nitric acid hydrate particles. If nucleation is homogeneous it implies that the freezing process is an inherent property of the particle, while heterogeneous freezing means that the extent of PSCs will depend in part on the number of nuclei available. The Polar Ozone and Aerosol Measurement (POAM)II and III satellites have been making observations of stratospheric aerosols and Polar Stratospheric Clouds (PSCs) since 1994. Recently, we have developed a technique that can discriminate between Type Ia and Ib PSCs using these observations. A statistical approach is employed to demonstrate the robustness of this approach and results are compared with lidar measurements. The technique is used to analyze observations from POAM II and II during Northern Hemisphere winters where significant PSC formation occurred with the objective of exploring Type I PSC formation mechanisms. The different PSCs identified using this method exhibit different growth curve as expressed as extinction versus temperature.

The Formation of Galaxies and Clusters.

ERIC Educational Resources Information Center

Gregory, Stephen; Morrison, Nancy D.

1985-01-01

Summarizes recent research on the formation of galaxies and clusters, focusing on research examining how the materials in galaxies seen today separated from the universal expansion and collapsed into stable bodies. A list of six nontechnical books and articles for readers with less background is included. (JN)

Modern Paradigm of Star Formation in the Galaxy

NASA Astrophysics Data System (ADS)

Sobolev, A. M.

2017-06-01

Understanding by the scientific community of the star formation processes in the Galaxy undergone significant changes in recent years. This is largely due to the development of the observational basis of astronomy in the infrared and submillimeter ranges. Analysis of new observational data obtained in the course of the Herschel project, by radio interferometer ALMA and other modern facilities significantly advanced our understanding of the structure of the regions of star formation, young stellar object vicinities and provided comprehensive data on the mass function of proto-stellar objects in a number of star-forming complexes of the Galaxy. Mapping of the complexes in molecular radio lines allowed to study their spatial and kinematic structure on the spatial scales of tens and hundreds of parsecs. The next breakthrough in this field can be achieved as a result of the planned project “Spektr-MM” (Millimetron) which implies a significant improvement in angular resolution and sensitivity. The use of sensitive interferometers allowed to investigate the details of star formation processes at small spatial scales - down to the size of the solar system (with the help of the ALMA), and even the Sun (in the course of the space project “Spektr-R” = RadioAstron). Significant contribution to the study of the processes of accretion is expected as a result of the project “Spektr-UV” (WSO-UV = “World Space Observatory - Ultraviolet”). Complemented with significant theoretical achievements obtained observational data have greatly promoted our understanding of the star formation processes.

Gender, Assessment and Students' Literacy Learning: Implications for Formative Assessment

ERIC Educational Resources Information Center

Murphy, Patricia; Ivinson, Gabrielle

2005-01-01

Formative assessment is intended to develop students' capacity to learn and increase the effectiveness of teaching. However, the extent to which formative assessment can meet these aims depends on the relationship between its conception and current conceptions of learning. In recent years concern about sex group differences in achievement has led…

Recent Results With Coupled Opto-Electronic Oscillators

NASA Astrophysics Data System (ADS)

Yao, X. S.; Maleki, L.; Wu, C.; Davis, L.; Forouhar, S.

1998-07-01

We present experimental results of coupled opto-electronic oscillators (COEOs) constructed with a semiconductor optical-amplifier-based ring laser, a semiconductor Fabry-Perot laser, and a semiconductor colliding-pulse mode-locked laser. Each COEO can simultaneously generate short optical pulses and spectrally pure RF signals. With these devices, we obtained optical pulses as short as 6 ps and RF signals as high in frequency as 18 GHz with a spectral purity comparable to an HP 8561B synthesizer. These experiments demonstrate that COEOs are promising compact sources for generating low jitter optical pulses and low phase noise RF/millimeter wave signals.

Recent results from the ARGO-YBJ experiment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Camarri, P.

2010-03-26

The ARGO-YBJ experiment at YangBaJing in Tibet (4300 m a.s.l.) has been taking data with its full layout since October 2007. Here we present the first significant results obtained in gamma-ray astronomy and cosmic-ray physics. Emphasis is placed on the analysis of gamma-ray emission from point-like sources (Crab Nebula, MRK 421), on the preliminary limit on the antiproton/proton flux ratio, on the large-scale cosmic-ray anisotropy and on the proton-air cross section. The performance of the detector is also discussed, and the perspectives of the experiment are outlined.

High-Resolution Spectroscopy of Mars: Recent Results and Implications for Atmospheric Evolution

NASA Technical Reports Server (NTRS)

Krasnopolsky, V. A.; Owen, T. C.; Maillard, J. P.

1999-01-01

It is believed that Earth, Venus, and Mars were formed by the same rocky and icy planetesimals, which resembled meteorites and comets in their composition, respectively. These planets are thus expected to have initially had the same chemical and isotope composition. Scaling the mass of the terrestrial ocean by the planetary mass ratio, the expected initial H2O abundance on Mars is a layer of about 1 km thick. Scaling the abundance of CO2 on Venus, the expected initial CO2 abundance on Mars is 15 bars. Evidently, significant parts of the initial H2O and CO2 abundances have been lost. Intense meteorite impact erosion and hydrodynamic escape of hydrogen (which could drag to escape more heavy species) were dominant loss processes in the first 0.8 Byr. Later, atmospheric sputtering by O+ ions resulted in the dissociation of CO2 and massive losses of O, C, and H. Formation of carbonates also reduced CO2 to its present abundance which currently exists in the atmosphere, on the polar caps, and is absorbed by regolith. Water loss is currently due to thermal escape of H and nonthermal escape of O, both formed by photodissociation of H2O. All loss processes resulted in fractionation of the H, O, and C isotopes. Therefore, the current isotope ratios in H2O and CO2 are clues to the history of volatiles on Mars. There are three tools to study H2O and CO2 isotopes in the martian atmosphere: (i) mass spectrometry from landing probes, (ii) analyses of Mars' gases trapped in the SNC meteorites which were ejected from Mars, and (iii) high-resolution spectroscopy of the H2O andCO2 bands. Method (i) is the best but is the most expensive. Mass spectrometers to be used should be designed for high-precision isotope measurements. Method (ii) makes it possible to reach an uncertainty +/- 0.1%. However, the obtained results are affected by some uncontrolled interactions: isotope fractionations of (1) trapped gases and (2) those released in pyrolysis, (3) contribution of the impactor, isotope

Human Capital Formation in the Gulf and MENA Region.

ERIC Educational Resources Information Center

Shaw, Ken E.

2001-01-01

Recent developments in human capital formation theories are particularly relevant to the Gulf and Middle Eastern and North African regions. Discusses recent western reconfigurations of the theory, noting how much local work must be done to reshape theory appropriately in the Middle East and explaining how issues relating to employment, education,…

Hydrocarbons in recent sediment of the Monterey Bay National Marine Sanctuary

USGS Publications Warehouse

Kvenvolden, K.A.; Hostettler, F.D.; Rosenbauer, R.W.; Lorenson, T.D.; Castle, W.T.; Sugarman, S.

2002-01-01

A complex mixture of hydrocarbons is present in the recent sediment of the Monterey Bay National Marine Sanctuary. Eighteen samples from the continental shelf between San Francisco and Monterey contain aliphatic and aromatic hydrocarbons showing biological contributions from both marine and terrigenous sources, with the terrigenous indicators more pronounced near Monterey. Of particular interest, however, is a low-level background of petroleum-related compounds, including 28,30-bisnorhopane and 18??+??(H)-oleanane, which are characteristic of many crude oils from the Monterey Formation of California. Thus, the sediments are overprinted by a regional chemical signature which may be derived from eroded Monterey Formation rocks and from onshore and offshore seeps releasing petroleum from Monterey Formation source rocks. ?? 2002 Elsevier Science B.V. All rights reserved.

Recent Results on Central Compact Objects

NASA Astrophysics Data System (ADS)

Halpern, Jules P.; Gotthelf, E. V.

2011-09-01

We will review the latest observational results and theoretical puzzles about the class of central compact objects (CCOs) in supernova remnants (SNRs), 10 isolated neutron stars (NSs) with steady, thermal X-ray emission and absence of a surrounding pulsar wind nebula. Three CCOs have detected X-ray pulsations, with periods of 0.105, 0.112, and 0.424 s. X-ray timing studies reveal that their spin-down rates are extremely small, implying dipole magnetic fields of only 3.e10-1.e11 G, which is unprecedented among the population of young pulsars. In the absence of a stronger magnetic field, it is difficult to explain the high temperatures of their surface hot spots, which may instead require a magnetic field configuration that is different from a centered dipole. While CCOs are inconspicuous relative to ordinary young pulsars and active magnetars, that they are found in SNRs in comparable numbers to other classes of NSs implies that they must represent a significant fraction of NS births. Nevertheless, they fall in a region of the P,P-dot diagram for radio pulsars that is underpopulated, so it is not clear if CCOs are intrinsically radio quiet, and what happens to their descendants, the "orphaned CCOs" whose SNRs have dissipated. It has been speculated that if their magnetic fields were initially strong but were buried by prompt fall-back of supernova debris, then the dipole field may eventually diffuse back to the surface, and CCOs could join the main population of ordinary pulsars. We will also discuss how the absence of detected pulsations from the majority of CCOs makes them difficult to distinguish from magnetars in quiescence, which have X-ray spectra and luminosities similar to those of CCOs. However, they can be distinguished with long-term monitoring, since magnetars are eventually variable, while CCOs are steady X-ray emitters.

Recent Results for the ECHo Experiment

NASA Astrophysics Data System (ADS)

Hassel, C.; Blaum, K.; Goodacre, T. Day; Dorrer, H.; Düllmann, Ch. E.; Eberhardt, K.; Eliseev, S.; Enss, C.; Filianin, P.; Fäßler, A.; Fleischmann, A.; Gastaldo, L.; Goncharov, M.; Hengstler, D.; Jochum, J.; Johnston, K.; Keller, M.; Kempf, S.; Kieck, T.; Köster, U.; Krantz, M.; Marsh, B.; Mokry, C.; Novikov, Yu. N.; Ranitzsch, P. C. O.; Rothe, S.; Rischka, A.; Runke, J.; Saenz, A.; Schneider, F.; Scholl, S.; Schüssler, R. X.; Simkovic, F.; Stora, T.; Thörle-Pospiech, P.; Türler, A.; Veinhard, M.; Wegner, M.; Wendt, K.; Zuber, K.

2016-08-01

The Electron Capture in ^{163}Ho experiment, ECHo, is designed to investigate the electron neutrino mass in the sub-eV range by means of the analysis of the calorimetrically measured spectrum following the electron capture (EC) in ^{163}Ho. Arrays of low-temperature metallic magnetic calorimeters (MMCs), read-out by microwave SQUID multiplexing, will be used in this experiment. With a first MMC prototype having the ^{163}Ho source ion-implanted into the absorber, we performed the first high energy resolution measurement of the EC spectrum, which demonstrated the feasibility of such an experiment. In addition to the technological challenges for the development of MMC arrays, which preserve the single pixel performance in terms of energy resolution and bandwidth, the success of the experiment relies on the availability of large ultra-pure ^{163}Ho samples, on the precise description of the expected spectrum, and on the identification and reduction of background. We present preliminary results obtained with standard MMCs developed for soft X-ray spectroscopy, maXs-20, where the ^{163}Ho ion-implantation was performed using a high-purity ^{163}Ho source produced by advanced chemical and mass separation. With these measurements, we aim at determining an upper limit for the background level due to source contamination and provide a refined description of the calorimetrically measured spectrum. We discuss the plan for a medium scale experiment, ECHo-1k, in which about 1000 mathrm {Bq} of high-purity ^{163}Ho will be ion-implanted into detector arrays. With one year of measuring time, we will be able to achieve a sensitivity on the electron neutrino mass below 20 eV/c^2 (90 % C.L.), improving the present limit by more than one order of magnitude. This experiment will guide the necessary developments to reach the sub-eV sensitivity.

Formation evaluation in liquid-dominated geothermal reservoirs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ershaghi, I.; Dougherty, E.E.; Handy, L.L.

1981-04-01

Studies relative to some formation evaluation aspects of geothermal reservoirs are reported. The particular reservoirs considered were the liquid dominated type with a lithology of the sedimentary nature. Specific problems of interest included the resistivity behavior of brines and rocks at elevated temperatures and studies on the feasibility of using the well log resistivity data to obtain estimates of reservoir permeability. Several papers summarizing the results of these studies were presented at various technical meetings for rapid dissemination of the results to potential users. These papers together with a summary of data most recently generated are included. A brief reviewmore » of the research findings precedes the technical papers. Separate abstracts were prepared for four papers. Five papers were abstracted previously for EDB.« less

Verbal Ability, Argument Order, and Attitude Formation

PubMed Central

Mozuraitis, Mindaugas; Chambers, Craig G.; Daneman, Meredyth

2016-01-01

The current study explored the interaction of verbal ability and presentation order on readers’ attitude formation when presented with two-sided arguments. Participants read arguments for and against compulsory voting and genetic engineering, and attitudes were assessed before and after reading the passages. Participants’ verbal ability was measured, combining vocabulary knowledge and reading comprehension skill. Results suggested that low verbal-ability participants were more persuaded by the most recent set of arguments whereas high verbal-ability participants formed attitudes independent of presentation order. Contrary to previous literature, individual differences in the personality trait need for cognition did not interact with presentation order. The results suggest that verbal ability is an important moderator of the effect of presentation order when formulating opinions from complex prose. PMID:27703437

Programed oil generation of the Zubair Formation, Southern Iraq oil fields: Results from Petromod software modeling and geochemical analysis

USGS Publications Warehouse

Al-Ameri, T. K.; Pitman, Janet K.; Naser, M.E.; Zumberge, J.; Al-Haydari, H. A.

2011-01-01

1D petroleum system modeling was performed on wells in each of four oil fields in South Iraq, Zubair (well Zb-47), Nahr Umr (well NR-9), West Qurna (well WQ-15 and 23), and Majnoon (well Mj-8). In each of these fields, deposition of the Zubair Formation was followed by continuous burial, reaching maximum temperatures of 100°C (equivalent to 0.70%Ro) at depths of 3,344–3,750 m of well Zb-47 and 3,081.5–3,420 m of well WQ-15, 120°C (equivalent to 0.78%Ro) at depths of 3,353–3,645 m of well NR-9, and 3,391–3,691.5 m of well Mj-8. Generation of petroleum in the Zubair Formation began in the late Tertiary, 10 million years ago. At present day, modeled transformation ratios (TR) indicate that 65% TR of its generation potential has been reached in well Zb-47, 75% TR in well NR-9 and 55-85% TR in West Qurna oil field (wells WQ-15 and WQ-23) and up to 95% TR in well Mj-8, In contrast, younger source rocks are immature to early mature (<20% TR), whereas older source rocks are mature to overmature (100% TR). Comparison of these basin modeling results, in Basrah region, are performed with Kifle oil field in Hilla region of western Euphrates River whereas the Zubair Formation is immature within temperature range of 65–70°C (0.50%Ro equivalent) with up to 12% (TR = 12%) hydrocarbon generation efficiency and hence poor generation could be assessed in this last location. The Zubair Formation was deposited in a deltaic environment and consists of interbedded shales and porous and permeable sandstones. In Basrah region, the shales have total organic carbon of 0.5–7.0 wt%, Tmax 430–470°C and hydrogen indices of up to 466 with S2 = 0.4–9.4 of kerogen type II & III and petroleum potential of 0.4–9.98 of good hydrocarbon generation, which is consistent with 55–95% hydrocarbon efficiency. These generated hydrocarbons had charged (in part) the Cretaceous and Tertiary reservoirs, especially the Zubair Formation itself, in the traps formed by Alpine

Recent Reanalysis Activities at ECMWF: Results from ERA-20C and Plans for ERA5

NASA Astrophysics Data System (ADS)

Dragani, R.; Hersbach, H.; Poli, P.; Pebeuy, C.; Hirahara, S.; Simmons, A.; Dee, D.

2015-12-01

This presentation will provide an overview of the most recent reanalysis activities performed at the European Centre for Medium-Range Weather Forecasts (ECMWF). A pilot reanalysis of the 20th-century (ERA-20C) has recently been completed. Funded through the European FP7 collaborative project ERA-CLIM, ERA-20C is part of a suite of experiments that also includes a model-only integration (ERA-20CM) and a land-surface reanalysis (ERA-20CL). Its data assimilation system is constrained by only surface observations obtained from ISPD (3.2.6) and ICOADS (2.5.1). Surface boundary conditions are provided by the Hadley Centre (HadISST2.1.0.0) and radiative forcing follows CMIP5 recommended data sets. First-guess uncertainty estimates are based on a 10-member ensemble of Data Assimilations, ERA-20C ensemble, run prior to ERA-20C using ten SST and sea-ice realizations from the Hadley Centre. In November 2014, the European Commission entrusted ECMWF to run on its behalf the Copernicus Climate Change Service (C3S) aiming at producing quality-assured information about the past, current and future states of the climate at both European and global scales. Reanalysis will be one of the main components of the C3S portfolio and the first one to be produced is a global modern era reanalysis (ERA5) covering the period from 1979 onwards. Based on a recent version of the ECMWF data assimilation system, ERA5 will replace the widely used ERA-Interim dataset. This new production will benefit from a much improved model, and better characterized and exploited observations compared to its predecessor. The first part of the presentation will focus on the ERA-20C production, provide an overview of its main characteristics and discuss some of the key results from its assessment. The second part of the talk will give an overview of ERA5, and briefly discuss some of its challenges.

Freedom and Second Nature in "The Formation of Reason"

ERIC Educational Resources Information Center

Bakhurst, David

2012-01-01

This article elaborates and defends a thesis prominent in my recent book, "The Formation of Reason"; namely, that "a human being gets to be free in the distinctive way that human beings are free through the acquisition of second nature". My treatment of this thesis in The Formation of Reason is much influenced by the philosophy of John McDowell.…

The radio-X-ray relation as a star formation indicator: results from the Very Large Array-Extended Chandra Deep Field-South

NASA Astrophysics Data System (ADS)

Vattakunnel, S.; Tozzi, P.; Matteucci, F.; Padovani, P.; Miller, N.; Bonzini, M.; Mainieri, V.; Paolillo, M.; Vincoletto, L.; Brandt, W. N.; Luo, B.; Kellermann, K. I.; Xue, Y. Q.

2012-03-01

In order to trace the instantaneous star formation rate (SFR) at high redshift, and thus help in understanding the relation between the different emission mechanisms related to star formation, we combine the recent 4-Ms Chandra X-ray data and the deep Very Large Array radio data in the Extended Chandra Deep Field-South region. We find 268 sources detected both in the X-ray and radio bands. The availability of redshifts for ˜95 per cent of the sources in our sample allows us to derive reliable luminosity estimates and the intrinsic properties from X-ray analysis for the majority of the objects. With the aim of selecting sources powered by star formation in both bands, we adopt classification criteria based on X-ray and radio data, exploiting the X-ray spectral features and time variability, taking advantage of observations scattered across more than 10 years. We identify 43 objects consistent with being powered by star formation. We also add another 111 and 70 star-forming candidates detected only in the radio and X-ray bands, respectively. We find a clear linear correlation between radio and X-ray luminosity in star-forming galaxies over three orders of magnitude and up to z˜ 1.5. We also measure a significant scatter of the order of 0.4 dex, higher than that observed at low redshift, implying an intrinsic scatter component. The correlation is consistent with that measured locally, and no evolution with redshift is observed. Using a locally calibrated relation between the SFR and the radio luminosity, we investigate the LX(2-10 keV)-SFR relation at high redshift. The comparison of the SFR measured in our sample with some theoretical models for the Milky Way and M31, two typical spiral galaxies, indicates that, with current data, we can trace typical spirals only at z≤ 0.2, and strong starburst galaxies with SFRs as high as ˜100 M⊙ yr-1, up to z˜ 1.5.

The indication of Martian gully formation processes by slope-area analysis

USGS Publications Warehouse

Conway, S.J.; Balme, M.R.; Murray, J.B.; Towner, M.C.; Okubo, C.H.; Grindrod, P.M.

2011-01-01

The formation process of recent gullies on Mars is currently under debate. This study aims to discriminate between the proposed formation processes - pure water flow, debris flow and dry mass wasting - through the application of geomorphological indices commonly used in terrestrial geomorphology. High-resolution digital elevation models (DEMs) of Earth and Mars were used to evaluate the drainage characteristics of small slope sections. Data from Earth were used to validate the hillslope, debris-flow and alluvial process domains previously found for large fluvial catchments on Earth, and these domains were applied to gullied and ungullied slopes on Mars. In accordance with other studies, our results indicate that debris flow is one of the main processes forming the Martian gullies that were being examined. The source of the water is predominantly distributed surface melting, not an underground aquifer. Evidence is also presented indicating that other processes may have shaped Martian crater slopes, such as ice-assisted creep and solifluction, in agreement with the proposed recent Martian glacial and periglacial climate. Our results suggest that, within impact craters, different processes are acting on differently oriented slopes, but further work is needed to investigate the potential link between these observations and changes in Martian climate. ?? The Geological Society of London 2011.

Re-initiation of bottom water formation in the East Sea (Japan Sea) in a warming world.

PubMed

Yoon, Seung-Tae; Chang, Kyung-Il; Nam, SungHyun; Rho, TaeKeun; Kang, Dong-Jin; Lee, Tongsup; Park, Kyung-Ae; Lobanov, Vyacheslav; Kaplunenko, Dmitry; Tishchenko, Pavel; Kim, Kyung-Ryul

2018-01-25

The East Sea (Japan Sea), a small marginal sea in the northwestern Pacific, is ventilated deeply down to the bottom and sensitive to changing surface conditions. Addressing the response of this marginal sea to the hydrological cycle and atmospheric forcing would be helpful for better understanding present and future environmental changes in oceans at the global and regional scales. Here, we present an analysis of observations revealing a slowdown of the long-term deepening in water boundaries associated with changes of water formation rate. Our results indicate that bottom (central) water formation has been enhanced (reduced) with more (less) oxygen supply to the bottom (central) layer since the 2000s. This paper presents a new projection that allows a three-layered deep structure, which retains bottom water, at least until 2040, contrasting previous results. This projection considers recent increase of slope convections mainly due to the salt supply via air-sea freshwater exchange and sea ice formation and decrease of open-ocean convections evidenced by reduced mixed layer depth in the northern East Sea, resulting in more bottom water and less central water formations. Such vigorous changes in water formation and ventilation provide certain implications on future climate changes.

The Evolution History of South China Sea: a Synthesis of Recent Geophysical, Geological, and Geochemical Results

NASA Astrophysics Data System (ADS)

Xue, M.; Li, L.; Chen, L.

2016-12-01

South China Sea (SCS) is located in the continental margin of Eurasia plate, where different geological blocks/tectonic plates interact. The dynamic mechanism of the formation of South China Sea (SCS) has been debated for decades. In this study, we first synthesize our geophysical results obtained in South China Sea, including an updated 3D velocity model from surface tomography using surrounding land stations and regional earthquakes, and shear wave splitting results obtained at surrounding land stations and OBS, using local, regional, and teleseismic earthquakes. The observed splitting results in South China Sea are complex: the fast polarization direction beneath the central basin is approximately NE-SW, nearly parallel to the extinct ridge in the central basin of SCS; however, the fast axis within the slab is trench-parallel outside the ridge subduction region. In 3D velocity models, subducting slabs are observed as dipping high velocity anomalies, and discontinuous low velocities are observed above the subduction slab, as well as in the basin. How the splitting observations are connected with the velocity models? How observations are linked to one another? How are the observations in central basin linked with surrounding region? We are aiming to link these observations themselves as well as with newly published results from geophysics, geochemistry, and geology in this region. Such a synthesis will improve our understanding about the evolution of South China Sea and facilitate new ideas.

Influence of plasma conditions on the defect formation mechanism in amorphous hydrogenated silicon

NASA Astrophysics Data System (ADS)

Kounavis, P.; Mataras, D.; Spiliopoulos, N.; Mytilineou, E.; Rapakoulias, D.

1994-02-01

The variation of a-Si:H film quality, deposited by a rf glow discharge of pure silane, is examined as a function of the interelectrode distance for two different pressures. Constant photocurrent and modulated photocurrent methods are used to estimate the magnitude and the shape of the defect states in the valence band and the conduction band, respectively. An effort is made to correlate the film quality parameters and the defect formation with the plasma macroscopic and microscopic parameters. The results suggest that, at low interelectrode distances, high sticking coefficient radicals modify the film growth and the defect formation mechanisms, leading to the deterioration of the film quality. The conclusions drawn are compared with the predictions of recent theoretical models concerning the defect formation in a-Si:H.

Recent advances in engineering topography mediated antibacterial surfaces

PubMed Central

Hasan, Jafar

2015-01-01

The tendency of bacterial cells to adhere and colonize a material surface leading to biofilm formation is a fundamental challenge underlying many different applications including microbial infections associated with biomedical devices and products. Although, bacterial attachment to surfaces has been extensively studied in the past, the effect of surface topography on bacteria–material interactions has received little attention until more recently. We review the recent progress in surface topography based approaches for engineering antibacterial surfaces. Biomimicry of antibacterial surfaces in nature is a popular strategy. Whereas earlier endeavors in the field aimed at minimizing cell attachment, more recent efforts have focused on developing bactericidal surfaces. However, not all such topography mediated bactericidal surfaces are necessarily cytocompatible thus underscoring the need for continued efforts for research in this area for developing antibacterial and yet cytocompatible surfaces for use in implantable biomedical applications. This mini-review provides a brief overview of the current strategies and challenges in the emerging field of topography mediated antibacterial surfaces. PMID:26372264

Recent advances in engineering topography mediated antibacterial surfaces

NASA Astrophysics Data System (ADS)

Hasan, Jafar; Chatterjee, Kaushik

2015-09-01

The tendency of bacterial cells to adhere and colonize a material surface leading to biofilm formation is a fundamental challenge underlying many different applications including microbial infections associated with biomedical devices and products. Although, bacterial attachment to surfaces has been extensively studied in the past, the effect of surface topography on bacteria-material interactions has received little attention until more recently. We review the recent progress in surface topography based approaches for engineering antibacterial surfaces. Biomimicry of antibacterial surfaces in nature is a popular strategy. Whereas earlier endeavors in the field aimed at minimizing cell attachment, more recent efforts have focused on developing bactericidal surfaces. However, not all such topography mediated bactericidal surfaces are necessarily cytocompatible thus underscoring the need for continued efforts for research in this area for developing antibacterial and yet cytocompatible surfaces for use in implantable biomedical applications. This mini-review provides a brief overview of the current strategies and challenges in the emerging field of topography mediated antibacterial surfaces.

Formation Design Strategy for SCOPE High-Elliptic Formation Flying Mission

NASA Technical Reports Server (NTRS)

Tsuda, Yuichi

2007-01-01

The new formation design strategy using simulated annealing (SA) optimization is presented. The SA algorithm is useful to survey a whole solution space of optimum formation, taking into account realistic constraints composed of continuous and discrete functions. It is revealed that this method is not only applicable for circular orbit, but also for high-elliptic orbit formation flying. The developed algorithm is first tested with a simple cart-wheel motion example, and then applied to the formation design for SCOPE. SCOPE is the next generation geomagnetotail observation mission planned in JAXA, utilizing a formation flying techonology in a high elliptic orbit. A distinctive and useful heuristics is found by investigating SA results, showing the effectiveness of the proposed design process.

Stalk Phase Formation: Effects of Dehydration and Saddle Splay Modulus

PubMed Central

Kozlovsky, Yonathan; Efrat, Avishay; Siegel, David A.; Kozlov, Michael M.

2004-01-01

One of the earliest lipid intermediates forming in the course of membrane fusion is the lipid stalk. Although many aspects of the stalk hypothesis were elaborated theoretically and confirmed by experiments it remained unresolved whether stalk formation is always an energy consuming process or if there are conditions where the stalks are energetically favorable and form spontaneously resulting in an equilibrium stalk phase. Motivated by a recent breakthrough experiments we analyze the physical factors determining the spontaneous stalk formation. We show that this process can be driven by interplay between two factors: the elastic energy of lipid monolayers including a contribution of the saddle splay deformation and the energy of hydration repulsion acting between apposing membranes. We analyze the dependence of stalk formation on the saddle splay (Gaussian) modulus of the lipid monolayers and estimate the values of this modulus based on the experimentally established phase boundary between the lamellar and the stalk phases. We suggest that fusion proteins can induce stalk formation just by bringing the membranes into close contact, and accumulating, at least locally, a sufficiently large energy of the hydration repulsion. PMID:15454446

Neon ion beam induced pattern formation on amorphous carbon surfaces

NASA Astrophysics Data System (ADS)

Bobes, Omar; Hofsäss, Hans; Zhang, Kun

2018-02-01

We investigate the ripple pattern formation on amorphous carbon surfaces at room temperature during low energy Ne ion irradiation as a function of the ion incidence angle. Monte Carlo simulations of the curvature coefficients applied to the Bradley-Harper and Cater-Vishnyakov models, including the recent extensions by Harrison-Bradley and Hofsäss predict that pattern formation on amorphous carbon thin films should be possible for low energy Ne ions from 250 eV up to 1500 eV. Moreover, simulations are able to explain the absence of pattern formation in certain cases. Our experimental results are compared with prediction using current linear theoretical models and applying the crater function formalism, as well as Monte Carlo simulations to calculate curvature coefficients using the SDTrimSP program. Calculations indicate that no patterns should be generated up to 45° incidence angle if the dynamic behavior of the thickness of the ion irradiated layer introduced by Hofsäss is taken into account, while pattern formation most pronounced from 50° for ion energy between 250 eV and 1500 eV, which are in good agreement with our experimental data.

Organosulfate Formation in Biogenic Secondary Organic Aerosol

EPA Science Inventory

Organosulfates of isoprene, α-pinene, and β-pinene have recently been identified in both laboratory-generated and ambient secondary organic aerosol (SOA). In this study, the mechanism and ubiquity of organosulfate formation in biogenic SOA is investigated by a comprehensive seri...

Nanobubble induced formation of quantum emitters in monolayer semiconductors

NASA Astrophysics Data System (ADS)

Shepard, Gabriella D.; Ajayi, Obafunso A.; Li, Xiangzhi; Zhu, X.-Y.; Hone, James; Strauf, Stefan

2017-06-01

The recent discovery of exciton quantum emitters in transition metal dichalcogenides (TMDCs) has triggered renewed interest of localized excitons in low-dimensional systems. Open questions remain about the microscopic origin previously attributed to dopants and/or defects as well as strain potentials. Here we show that the quantum emitters can be deliberately induced by nanobubble formation in WSe2 and BN/WSe2 heterostructures. Correlations of atomic-force microscope and hyperspectral photoluminescence images reveal that the origin of quantum emitters and trion disorder is extrinsic and related to 10 nm tall nanobubbles and 70 nm tall wrinkles, respectively. We further demonstrate that ‘hot stamping’ results in the absence of 0D quantum emitters and trion disorder. The demonstrated technique is useful for advances in nanolasers and deterministic formation of cavity-QED systems in monolayer materials.

Dengue Virus Serotype-2 Interferes with the Formation of Neutrophil Extracellular Traps.

PubMed

Moreno-Altamirano, Maria Maximina B; Rodríguez-Espinosa, Oscar; Rojas-Espinosa, Oscar; Pliego-Rivero, Bernardo; Sánchez-García, Francisco J

2015-01-01

Neutrophils play an important role in the control of pathogens through several mechanisms, including phagocytosis and the formation of neutrophil extracellular traps (NETs). The latter consists of DNA as a backbone with embedded antimicrobial peptides, histones, and proteases, providing a matrix to entrap and in some cases to kill microbes. Some metabolic requirements for NET formation have recently been described. The virus-induced formation of NETs and the role of these traps in viral infections remain scarcely reported. Here, we analyzed whether dengue virus serotype-2 (DENV-2) induces NET formation and the DENV-2 effect on phorbol myristate acetate (PMA)-induced NETs. Peripheral blood-derived neutrophils were exposed in vitro to DENV-2 or exposed to DENV-2 and then stimulated with PMA. NET formation was assessed by fluorescence microscopy. Cell membrane Glut-1, glucose uptake, and reactive oxygen species (ROS) production were assessed. DENV-2 does not induce the formation of NETs. Moreover, DENV-2 inhibits PMA-induced formation of NETs by about 80%. This effect is not related to the production of ROS. The mechanism seemingly accountable for this inhibitory effect is the DENV-2-mediated inhibition of PMA-induced glucose uptake by neutrophils. Our results suggest that DENV-2 inhibits glucose uptake as a metabolism-based way to avoid the formation of NETs. © 2015 S. Karger AG, Basel.

Acid-base metabolism: implications for kidney stones formation.

PubMed

Hess, Bernhard

2006-04-01

The physiology and pathophysiology of renal H+ ion excretion and urinary buffer systems are reviewed. The main focus is on the two major conditions related to acid-base metabolism that cause kidney stone formation, i.e., distal renal tubular acidosis (dRTA) and abnormally low urine pH with subsequent uric acid stone formation. Both the entities can be seen on the background of disturbances of the major urinary buffer system, NH3+ <--> NH4+. On the one hand, reduced distal tubular secretion of H+ ions results in an abnormally high urinary pH and either incomplete or complete dRTA. On the other hand, reduced production/availability of NH4+ is the cause of an abnormally low urinary pH, which predisposes to uric acid stone formation. Most recent research indicates that the latter abnormality may be a renal manifestation of the increasingly prevalent metabolic syndrome. Despite opposite deviations from normal urinary pH values, both the dRTA and uric acid stone formation due to low urinary pH require the same treatment, i.e., alkali. In the dRTA, alkali is needed for improving the body's buffer capacity, whereas the goal of alkali treatment in uric acid stone formers is to increase the urinary pH to 6.2-6.8 in order to minimize uric acid crystallization.

Recent advances in the risk assessment of melamine and cyanuric acid in animal feed

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dorne, Jean Lou, E-mail: jean-lou.dorne@efsa.europa.eu; Doerge, Daniel R.; Vandenbroeck, Marc

Melamine can be present at low levels in food and feed mostly from its legal use as a food contact material in laminates and plastics, as a trace contaminant in nitrogen supplements used in animal feeds, and as a metabolite of the pesticide cyromazine. The mechanism of toxicity of melamine involves dose-dependent formation of crystals with either endogenous uric acid or a structural analogue of melamine, cyanuric acid, in renal tubules resulting in potential acute kidney failure. Co-exposure to melamine and cyanuric acid in livestock, fish, pets and laboratory animals shows higher toxicity compared with melamine or cyanuric acid alone.more » Evidence for crystal formation between melamine and other structural analogs i.e. ammelide and ammeline is limited. Illegal pet food adulterations with melamine and cyanuric acid and adulteration of milk with melamine resulted in melamine–cyanuric acid crystals, kidney damage and deaths of cats and dogs and melamine–uric acid stones, hospitalisation and deaths of children in China respectively. Following these incidents, the tolerable daily intake for melamine was re-evaluated by the U.S. Food and Drug Administration, the World Health Organisation, and the Scientific Panel on Contaminants in the Food Chain of the European Food Safety Authority (EFSA). This review provides an overview of toxicology, the adulteration incidents and risk assessments for melamine and its structural analogues. Particular focus is given to the recent EFSA risk assessment addressing impacts on animal and human health of background levels of melamine and structural analogues in animal feed. Recent research and future directions are discussed. - Highlights: ► Melamine in food and feed. ► Forms crystals in kidney with uric acid or cyanuric acid. ► Toxicity higher with cyanuric acid. ► Recent EFSA risk assessment. ► Animal and human health.« less

Epigenetic mechanisms: critical contributors to long-term memory formation.

PubMed

Lubin, Farah D; Gupta, Swati; Parrish, R Ryley; Grissom, Nicola M; Davis, Robin L

2011-12-01

Recent advances in chromatin biology have identified a role for epigenetic mechanisms in the regulation of neuronal gene expression changes, a necessary process for proper synaptic plasticity and memory formation. Experimental evidence for dynamic chromatin remodeling influencing gene transcription in postmitotic neurons grew from initial reports describing posttranslational modifications of histones, including phosphorylation and acetylation occurring in various brain regions during memory consolidation. An accumulation of recent studies, however, has also highlighted the importance of other epigenetic modifications, such as DNA methylation and histone methylation, as playing a role in memory formation. This present review examines learning-induced gene transcription by chromatin remodeling underlying long-lasting changes in neurons, with direct implications for the study of epigenetic mechanisms in long-term memory formation and behavior. Furthermore, the study of epigenetic gene regulation, in conjunction with transcription factor activation, can provide complementary lines of evidence to further understanding transcriptional mechanisms subserving memory storage.

Sensitivity analysis and multidisciplinary optimization for aircraft design: Recent advances and results

NASA Technical Reports Server (NTRS)

Sobieszczanski-Sobieski, Jaroslaw

1988-01-01

Optimization by decomposition, complex system sensitivity analysis, and a rapid growth of disciplinary sensitivity analysis are some of the recent developments that hold promise of a quantum jump in the support engineers receive from computers in the quantitative aspects of design. Review of the salient points of these techniques is given and illustrated by examples from aircraft design as a process that combines the best of human intellect and computer power to manipulate data.

Report on recent results of the PERCIVAL soft X-ray imager

NASA Astrophysics Data System (ADS)

Khromova, A.; Cautero, G.; Giuressi, D.; Menk, R.; Pinaroli, G.; Stebel, L.; Correa, J.; Marras, A.; Wunderer, C. B.; Lange, S.; Tennert, M.; Niemann, M.; Hirsemann, H.; Smoljanin, S.; Reza, S.; Graafsma, H.; Göttlicher, P.; Shevyakov, I.; Supra, J.; Xia, Q.; Zimmer, M.; Guerrini, N.; Marsh, B.; Sedgwick, I.; Nicholls, T.; Turchetta, R.; Pedersen, U.; Tartoni, N.; Hyun, H. J.; Kim, K. S.; Rah, S. Y.; Hoenk, M. E.; Jewell, A. D.; Jones, T. J.; Nikzad, S.

2016-11-01

The PERCIVAL (Pixelated Energy Resolving CMOS Imager, Versatile And Large) soft X-ray 2D imaging detector is based on stitched, wafer-scale sensors possessing a thick epi-layer, which together with back-thinning and back-side illumination yields elevated quantum efficiency in the photon energy range of 125-1000 eV. Main application fields of PERCIVAL are foreseen in photon science with FELs and synchrotron radiation. This requires high dynamic range up to 105 ph @ 250 eV paired with single photon sensitivity with high confidence at moderate frame rates in the range of 10-120 Hz. These figures imply the availability of dynamic gain switching on a pixel-by-pixel basis and a highly parallel, low noise analog and digital readout, which has been realized in the PERCIVAL sensor layout. Different aspects of the detector performance have been assessed using prototype sensors with different pixel and ADC types. This work will report on the recent test results performed on the newest chip prototypes with the improved pixel and ADC architecture. For the target frame rates in the 10-120 Hz range an average noise floor of 14e- has been determined, indicating the ability of detecting single photons with energies above 250 eV. Owing to the successfully implemented adaptive 3-stage multiple-gain switching, the integrated charge level exceeds 4 · 106 e- or 57000 X-ray photons at 250 eV per frame at 120 Hz. For all gains the noise level remains below the Poisson limit also in high-flux conditions. Additionally, a short overview over the updates on an oncoming 2 Mpixel (P2M) detector system (expected at the end of 2016) will be reported.

The BepiColombo SERENA/ELENA sensor. Approaching final delivery: sensor description and recent results

NASA Astrophysics Data System (ADS)

Orsini, S.; Selci, S.; Di Lellis, A. M.; Mura, A.; De Angelis, E.; Milillo, A.; Leoni, R.; Dandouras, I.; Scheer, J.; Wurz, P.

2012-04-01

The neutral sensor ELENA (Emitted Low-Energy Neutral Atoms) for the ESA cornerstone BepiColombo mission to Mercury (in the SERENA instrument package) is a new kind of low energetic neutral atoms instrument, mostly devoted to sputtering emission from planetary surfaces, from E ~20 eV up to E~5 keV, within 1-D (4.5°x76°). ELENA is a Time-of-Flight (TOF) system, based on oscillating shutter (operated at frequencies up to 50 kHz) and mechanical gratings: the incoming neutral particles directly impinge upon the entrance with a definite timing (START) and arrive to a STOP detector after a flight path. In this way the low-energy neutral particles are directly detected, without using elements of interaction. The new results of the development of the BepiColombo SERENA/ELENA instrument are presented in the frame of the scientific items (instrument simulations, laboratory testing, etc.). In particular, the actual status of the ELENA TOF sections (shuttering system and MCPs) are reported in the light of recent testing results. The sensor performances are investigated, as well as their capability to accomplish the scientific requirements (new deflector system, shuttering functionality test, MCP efficiency, piezo driver and proximity boards, etc.).

Complex organic molecules during low-mass star formation: Pilot survey results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Öberg, Karin I.; Graninger, Dawn; Lauck, Trish, E-mail: koberg@cfa.harvard.edu

Complex organic molecules (COMs) are known to be abundant toward some low-mass young stellar objects (YSOs), but how these detections relate to typical COM abundance are not yet understood. We aim to constrain the frequency distribution of COMs during low-mass star formation, beginning with this pilot survey of COM lines toward six embedded YSOs using the IRAM 30 m Telescope. The sample was selected from the Spitzer c2d ice sample and covers a range of ice abundances. We detect multiple COMs, including CH{sub 3}CN, toward two of the YSOs, and tentatively toward a third. Abundances with respect to CH{sub 3}OHmore » vary between 0.7% and 10%. This sample is combined with previous COM observations and upper limits to obtain a frequency distributions of CH{sub 3}CN, HCOOCH{sub 3}, CH{sub 3}OCH{sub 3}, and CH{sub 3}CHO. We find that for all molecules more than 50% of the sample have detections or upper limits of 1%-10% with respect to CH{sub 3}OH. Moderate abundances of COMs thus appear common during the early stages of low-mass star formation. A larger sample is required, however, to quantify the COM distributions, as well as to constrain the origins of observed variations across the sample.« less

Numerical simulations of catastrophic disruption: Recent results

NASA Technical Reports Server (NTRS)

Benz, W.; Asphaug, E.; Ryan, E. V.

1994-01-01

Numerical simulations have been used to study high velocity two-body impacts. In this paper, a two-dimensional Largrangian finite difference hydro-code and a three-dimensional smooth particle hydro-code (SPH) are described and initial results reported. These codes can be, and have been, used to make specific predictions about particular objects in our solar system. But more significantly, they allow us to explore a broad range of collisional events. Certain parameters (size, time) can be studied only over a very restricted range within the laboratory; other parameters (initial spin, low gravity, exotic structure or composition) are difficult to study at all experimentally. The outcomes of numerical simulations lead to a more general and accurate understanding of impacts in their many forms.

A GLIMPSE of Star Formation in the Outer Galaxy

NASA Astrophysics Data System (ADS)

Winston, Elaine; Hora, Joseph L.; Tolls, Volker

2018-01-01

The wealth of infrared data provided by recent infrared missions such as Spitzer, Herschel, and WISE has yet to be fully mined in the study of star formation in the outer galaxy. The nearby galaxy and massive star forming regions towards the galactic center have been extensively studied. However the outer regions of the Milky Way, where the metallicity is intermediate in value between the inner galactic disk and the Magellanic Clouds, has not been systematically studied. We are using Spitzer/IRAC’s GLIMPSE (Galactic Legacy Infrared Mid-plane Survey Extraordinaire) observations of the galactic plane at 3.6, 4.5, 5.8, and 8.0 microns to identify young stellar objects (YSOs) via their disk emission in the mid-infrared. A tiered clustering analysis is then performed: preliminary large scale clustering is identified across the field using a Density-Based Spatial Clustering of Applications with Noise (DBSCAN) technique. Smaller scale sub clustering within these regions is performed using an implementation of the Minimum Spanning Tree (MST) technique. The YSOs are then compared to known objects in the SIMBAD catalogue and their photometry and cluster membership is augmented using available Herschel and WISE photometry. We compare our results to those in the inner galaxy to determine how dynamical processes and environmental factors affect the star formation efficiency. These results will have applications to the study of star formation in other galaxies, where only global properties can be determined. We will present here the results of our initial investigation into star formation in the outer galaxy using the Spitzer/GLIMPSE observations of the SMOG field.

REVIEWS OF TOPICAL PROBLEMS: Large-scale star formation in galaxies

NASA Astrophysics Data System (ADS)

Efremov, Yurii N.; Chernin, Artur D.

2003-01-01

A brief review is given of the history of modern ideas on the ongoing star formation process in the gaseous disks of galaxies. Recent studies demonstrate the key role of the interplay between the gas self-gravitation and its turbulent motions. The large scale supersonic gas flows create structures of enhanced density which then give rise to the gravitational condensation of gas into stars and star clusters. Formation of star clusters, associations and complexes is considered, as well as the possibility of isolated star formation. Special emphasis is placed on star formation under the action of ram pressure.

Biofilm Formation by Cryptococcus neoformans.

PubMed

Martinez, Luis R; Casadevall, Arturo

2015-06-01

The fungus Cryptococcus neoformans possesses a polysaccharide capsule and can form biofilms on medical devices. The increasing use of ventriculoperitoneal shunts to manage intracranial hypertension associated with cryptococcal meningoencephalitis highlights the importance of investigating the biofilm-forming properties of this organism. Like other microbe-forming biofilms, C. neoformans biofilms are resistant to antimicrobial agents and host defense mechanisms, causing significant morbidity and mortality. This chapter discusses the recent advances in the understanding of cryptococcal biofilms, including the role of its polysaccharide capsule in adherence, gene expression, and quorum sensing in biofilm formation. We describe novel strategies for the prevention or eradication of cryptococcal colonization of medical prosthetic devices. Finally, we provide fresh thoughts on the diverse but interesting directions of research in this field that may result in new insights into C. neoformans biology.

Outstanding challenges in the seismological study of volcanic processes: Results from recent U.S. and European community-wide discussion workshops

NASA Astrophysics Data System (ADS)

Roman, D. C.; Rodgers, M.; Mather, T. A.; Power, J. A.; Pyle, D. M.

2014-12-01

Observations of volcanically induced seismicity are essential for eruption forecasting and for real-time and near-real-time warnings of hazardous volcanic activity. Studies of volcanic seismicity and of seismic wave propagation also provide critical understanding of subsurface magmatic systems and the physical processes associated with magma genesis, transport, and eruption. However, desipite significant advances in recent years, our ability to successfully forecast volcanic eruptions and fully understand subsurface volcanic processes is limited by our current understanding of the source processes of volcano-seismic events, the effects on seismic wave propagation within volcanic structures, limited data, and even the non-standardized terminology used to describe seismic waveforms. Progress in volcano seismology is further hampered by inconsistent data formats and standards, lack of state-of-the-art hardware and professional technical staff, as well as a lack of widely adopted analysis techniques and software. Addressing these challenges will not only advance scientific understanding of volcanoes, but also will lead to more accurate forecasts and warnings of hazardous volcanic eruptions that would ultimately save lives and property world-wide. Two recent workshops held in Anchorage, Alaska, and Oxford, UK, represent important steps towards developing a relationship among members of the academic community and government agencies, focused around a shared, long-term vision for volcano seismology. Recommendations arising from the two workshops fall into six categories: 1) Ongoing and enhanced community-wide discussions, 2) data and code curation and dissemination, 3) code development, 4) development of resources for more comprehensive data mining, 5) enhanced strategic seismic data collection, and 6) enhanced integration of multiple datasets (including seismicity) to understand all states of volcano activity through space and time. As presented sequentially above, these

Surveying Low-Mass Star Formation with the Submillimeter Array

NASA Astrophysics Data System (ADS)

Dunham, Michael

2018-01-01

Large astronomical surveys yield important statistical information that can’t be derived from single-object and small-number surveys. In this talk I will review two recent surveys in low-mass star formation undertaken by the Submillimeter Array (SMA): a millimeter continuum survey of disks surrounding variably accreting young stars, and a complete continuum and molecular line survey of all protostars in the nearby Perseus Molecular Cloud. I will highlight several new insights into the processes by which low-mass stars gain their mass that have resulted from the statistical power of these surveys.

The expected results method for data verification

NASA Astrophysics Data System (ADS)

Monday, Paul

2016-05-01

The credibility of United States Army analytical experiments using distributed simulation depends on the quality of the simulation, the pedigree of the input data, and the appropriateness of the simulation system to the problem. The second of these factors is best met by using classified performance data from the Army Materiel Systems Analysis Activity (AMSAA) for essential battlefield behaviors, like sensors, weapon fire, and damage assessment. Until recently, using classified data has been a time-consuming and expensive endeavor: it requires significant technical expertise to load, and it is difficult to verify that it works correctly. Fortunately, new capabilities, tools, and processes are available that greatly reduce these costs. This paper will discuss these developments, a new method to verify that all of the components are configured and operate properly, and the application to recent Army Capabilities Integration Center (ARCIC) experiments. Recent developments have focused improving the process to load the data. OneSAF has redesigned their input data file formats and structures so that they correspond exactly with the Standard File Format (SFF) defined by AMSAA, ARCIC developed a library of supporting configurations that correlate directly to the AMSAA nomenclature, and the Entity Validation Tool was designed to quickly execute the essential models with a test-jig approach to identify problems with the loaded data. The missing part of the process is provided by the new Expected Results Method. Instead of the usual subjective assessment of quality, e.g., "It looks about right to me", this new approach compares the performance of a combat model with authoritative expectations to quickly verify that the model, data, and simulation are all working correctly. Integrated together, these developments now make it possible to use AMSAA classified performance data with minimal time and maximum assurance that the experiment's analytical results will be of the highest

Lysozyme pattern formation in evaporating droplets

NASA Astrophysics Data System (ADS)

Gorr, Heather Meloy

Liquid droplets containing suspended particles deposited on a solid, flat surface generally form ring-like structures due to the redistribution of solute during evaporation (the "coffee ring effect"). The forms of the deposited patterns depend on complex interactions between solute(s), solvent, and substrate in a rapidly changing, far from equilibrium system. Solute self-organization during evaporation of colloidal sessile droplets has attracted the attention of researchers over the past few decades due to a variety of technological applications. Recently, pattern formation during evaporation of various biofluids has been studied due to potential applications in medical screening and diagnosis. Due to the complexity of 'real' biological fluids and other multicomponent systems, a comprehensive understanding of pattern formation during droplet evaporation of these fluids is lacking. In this PhD dissertation, the morphology of the patterns remaining after evaporation of droplets of a simplified model biological fluid (aqueous lysozyme solutions + NaCl) are examined by atomic force microscopy (AFM) and optical microscopy. Lysozyme is a globular protein found in high concentration, for example, in human tears and saliva. The drop diameters, D, studied range from the micro- to the macro- scale (1 microm -- 2 mm). In this work, the effect of evaporation conditions, solution chemistry, and heat transfer within the droplet on pattern formation is examined. In micro-scale deposits of aqueous lysozyme solutions (1 microm < D < 50 microm), the protein motion and the resulting dried residue morphology are highly influenced by the decreased evaporation time of the drop. The effect of electrolytes on pattern formation is also investigated by adding varying concentrations NaCl to the lysozyme solutions. Finally, a novel pattern recognition program is described and implemented which classifies deposit images by their solution chemistries. The results presented in this Ph

Global Electromagnetic Imaging of Lithosphere and Upper Mantle from Space and Ground. Recent Results and Challenges

NASA Astrophysics Data System (ADS)

Kuvshinov, A. V.

2016-12-01

Electrical conductivity is one of the characteristic physical parameters of materials making up Earth's interior which is sensitive to variations of temperature, chemical composition, water content, and partial melt. As a consequence, estimating lithosphere and upper mantle (LUM) electrical conductivity structure is a potentially strong tool for mapping their chemistry, mineralogy and physical structure thus presenting a complementary method to seismic studies that focus on LUM elastic properties. Global electromagnetic (EM) studies, which provide information on LUM electrical conductivity, have attracted increasing interest during the last decade, mainly for three reasons. A primary reason is the recent growth in the amount of EM data available, especially from low-Earth orbiting magnetic satellite missions (Oersted, CHAMP, SAC-C, and Swarm). A second reason is the great interest in the characterization of the three-dimensional properties of Earth's interior on a global scale. Finally, the interest has also resulted from the significant methodological progress made during the last years in EM data analysis, forward modelling and inversion. In this talk I will summarize advances and challenges in EM data interpretation, and present recent global and regional models of LUM conductivity derived from satellite and ground-based data. I will also discuss possible topics for future research.

Results from the Splash Survey: Spectroscopic and Photometric Landscape of Andromeda's Stellar Halo

NASA Astrophysics Data System (ADS)

Guhathakurta, Puragra; SPLASH Collaboration

2009-01-01

Detailed studies of nearby galaxies provide vital clues about their formation and evolutionary history. This "fossil record" approach is complementary to direct look-back studies of distant galaxies. Our Galaxy and the Andromeda spiral galaxy (M31) have long been cornerstones in the former category. M31 provides an external perspective on a large galaxy similar to our own and yet is close enough to allow detailed studies of individual stars. In my talk, I will present results from the SPLASH collaboration: Spectroscopic and Photometric Landscape of Andromeda's Stellar Halo. The collective data set from this large international team includes thousands of Keck/DEIMOS spectra of individual red giant branch stars, ground-based deep wide-field imaging and photometry with KPNO/Mosaic, CFHT/MegaCam, and Subaru/Suprime-Cam, and ultra-deep pencil-beam probes with HST/ACS imaging reaching below the main-sequence turnoff. Our recent discovery of an extended stellar halo in M31 (R > 150 kpc) shows that most previous studies of its spheroid have been sampling its inner bulge-like spheroidal component, not its halo. In my talk I will touch upon several related topics related to the general theme of hierarchical galaxy formation including: M31's global structure and subcomponents (halo, bulge/central bar, and disk), stellar dynamics, statistical properties of substructure, detailed chemical abundance measurements, detailed forensic reconstruction of recent collision events, dwarf satellites as tracers and building blocks of larger galaxies, and empirical constraints on the tangential motion of the M31 system. I will also discuss recent results on the chemical abundance of the lowest luminosity Galactic satellites (recently discovered by SDSS) and implications for the formation of the Milky Way halo. This research was supported by funds from the National Science Foundation, NASA, and the Institute for Geophysics and Planetary Physics.

Prophages and Growth Dynamics Confound Experimental Results with Antibiotic-Tolerant Persister Cells

PubMed Central

Fino, Cinzia; Sørensen, Michael A.; Semsey, Szabolcs

2017-01-01

ABSTRACT Bacterial persisters are phenotypic variants that survive antibiotic treatment in a dormant state and can be formed by multiple pathways. We recently proposed that the second messenger (p)ppGpp drives Escherichia coli persister formation through protease Lon and activation of toxin-antitoxin (TA) modules. This model found considerable support among researchers studying persisters but also generated controversy as part of recent debates in the field. In this study, we therefore used our previous work as a model to critically examine common experimental procedures to understand and overcome the inconsistencies often observed between results of different laboratories. Our results show that seemingly simple antibiotic killing assays are very sensitive to variations in culture conditions and bacterial growth phase. Additionally, we found that some assay conditions cause the killing of antibiotic-tolerant persisters via induction of cryptic prophages. Similarly, the inadvertent infection of mutant strains with bacteriophage ϕ80, a notorious laboratory contaminant, apparently caused several of the phenotypes that we reported in our previous studies. We therefore reconstructed all infected mutants and probed the validity of our model of persister formation in a refined assay setup that uses robust culture conditions and unravels the dynamics of persister cells through all bacterial growth stages. Our results confirm the importance of (p)ppGpp and Lon but no longer support a role of TA modules in E. coli persister formation under unstressed conditions. We anticipate that the results and approaches reported in our study will lay the ground for future work in the field. PMID:29233898

Recent results of Daya Bay reactor neutrino experiment

NASA Astrophysics Data System (ADS)

Leitner, R.; Daya Bay Collaboration

2017-04-01

The Daya Bay reactor neutrino experiment has been designed to precisely measure the least known neutrino mixing angle θ13. In March 2012, Daya Bay collaboration announced [Daya Bay Collaboration (F. P. An et al.), Observation of electron-antineutrino disappearance at Daya Bay, Phys. Rev. Lett. 108 (2012) 171803] the observation of non-zero value of sin2 ⁡ 2θ13. Because of large statistics of detected antineutrinos and excellent performance of the experiment, Daya Bay continuously improves the precision of world best measurement of sin2 ⁡ 2θ13. In addition it provides results on neutrino mass splitting Δ mee2 competitive with measurements of other experiments, results on precise measurement of reactor fluxes and on limits of the existence of hypothetical fourth neutrino. In this paper, we report the results available by the time of the 6th Capri workshop: the measurement of oscillation parameters sin2 ⁡ (2θ13) = 0.084 ± 0.005 and | Δmee2 | = (2.42 ± 0.11) ×10-3eV2 [Daya Bay Collaboration (F. P. An et al.), New Measurement of Antineutrino Oscillation with the Full Detector Configuration at Daya Bay, Phys. Rev. Lett. 115 (2015) no. 11, 111802], searches for sterile neutrinos [Daya Bay Collaboration (F. P. An et al.) Search for a Light Sterile Neutrino at Daya Bay, Phys. Rev. Lett. 113 (2014) 141802] and precise measurement of reactor neutrino flux [Daya Bay Collaboration (F. P. An et al.), Measurement of the Reactor Anti-neutrino Flux and Spectrum at Daya Bay, Phys. Rev. Lett. 116 (2016) no. 6, 061801]. These are based on 621 days of measurement, most of the data has been taken in full detector configuration. More precise results [Daya Bay Collaboration (F. P. An et al.), Measurement of electron antineutrino oscillation based on 1230 days of operation of the Daya Bay experiment, arxiv:arXiv:1610.04802] with 1230 days of operation have been presented few weeks later at the Neutrino 2016 conference.

Particle Formation and Product Formulation Using Supercritical Fluids.

PubMed

Knez, Željko; Knez Hrnčič, Maša; Škerget, Mojca

2015-01-01

Traditional methods for solids processing involve either high temperatures, necessary for melting or viscosity reduction, or hazardous organic solvents. Owing to the negative impact of the solvents on the environment, especially on living organisms, intensive research has focused on new, sustainable methods for the processing of these substances. Applying supercritical fluids for particle formation may produce powders and composites with special characteristics. Several processes for formation and design of solid particles using dense gases have been studied intensively. The unique thermodynamic and fluid-dynamic properties of supercritical fluids can be used also for impregnation of solid particles or for the formation of solid powderous emulsions and particle coating, e.g., for formation of solids with unique properties for use in different applications. We give an overview of the application of sub- and supercritical fluids as green processing media for particle formation processes and present recent advances and trends in development.

Dark-ages reionization and galaxy formation simulation - XIII. AGN quenching of high-redshift star formation in ZF-COSMOS-20115

NASA Astrophysics Data System (ADS)

Qin, Yuxiang; Mutch, Simon J.; Duffy, Alan R.; Geil, Paul M.; Poole, Gregory B.; Mesinger, Andrei; Wyithe, J. Stuart B.

2017-11-01

Massive quiescent galaxies (MQGs) are thought to have formed stars rapidly at early times followed by a long period of quiescence. The recent discovery of a MQG, ZF-COSMOS-20115 at z ˜ 4, only 1.5 Gyr after the big bang, places new constraints on galaxy growth and the role of feedback in early star formation. Spectroscopic follow-up confirmed ZF-COSMOS-20115 as a MQG at z = 3.717 with an estimated stellar mass of ˜1011 M⊙, showing no evidence of recent star formation. We use the Meraxes semi-analytic model to investigate how ZF-COSMOS-20115 analogues build stellar mass, and why they become quiescent. We identify three analogue galaxies with similar properties to ZF-COSMOS-20115. We find that ZF-COSMOS-20115 is likely hosted by a massive halo with virial mass of ˜1013 M⊙, having been through significant mergers at early times. These merger events drove intense growth of the nucleus, which later prevented cooling and quenched star formation. Therefore, ZF-COSMOS-20115 is unlikely to have experienced strong or extended star formation events at z < 3.7. We find that the analogues host the most massive black holes in our simulation and were luminous quasars at z ˜ 5, indicating that ZF-COSMOS-20115 and other MQGs may be the descendants of high-redshift quasars. In addition, the model suggests that ZF-COSMOS-20115 formed in a region of intergalactic medium that was reionized early.

Bonded exciplex formation: electronic and stereoelectronic effects.

PubMed

Wang, Yingsheng; Haze, Olesya; Dinnocenzo, Joseph P; Farid, Samir; Farid, Ramy S; Gould, Ian R

2008-12-18

As recently proposed, the singlet-excited states of several cyanoaromatics react with pyridine via bonded-exciplex formation, a novel concept in photochemical charge transfer reactions. Presented here are electronic and steric effects on the quenching rate constants, which provide valuable support for the model. Additionally, excited-state quenching in poly(vinylpyridine) is strongly inhibited both relative to that in neat pyridine and also to conventional exciplex formation in polymers, consistent with a restrictive orientational requirement for the formation of bonded exciplexes. Examples of competing reactions to form both conventional and bonded exciplexes are presented, which illustrate the delicate balance between these two processes when their reaction energetics are similar. Experimental and computational evidence is provided for the formation of a bonded exciplex in the reaction of the singlet excited state of 2,6,9,10-tetracyanoanthracene (TCA) with an oxygen-substituted donor, dioxane, thus expanding the scope of bonded exciplexes.

Microwave-induced formation of oligomeric amyloid aggregates.

PubMed

Lee, Wonseok; Choi, Yeseong; Lee, Sang Won; Kim, Insu; Lee, Dongtak; Hong, Yoochan; Lee, Gyudo; Yoon, Dae Sung

2018-08-24

Amyloid aggregates have emerged as a significant hallmark of neurodegenerative diseases such as Alzheimer's and Parkinson's diseases. Although it has been recently reported that microwave heating induces amyloid aggregation compared with conventional heating methods, the mechanism of amyloid aggregate induction has remained unclear. In this study, we investigated the formation of oligomeric amyloid aggregates (OAAs) by microwave irradiation at microscale volumes of solution. Microwave irradiation of protein monomer solution triggered rapid formation of OAAs within 7 min. We characterized the formation of OAAs using atomic force microscopy, thioflavin T fluorescent assay and circular dichroism. In the microwave system, we also investigated the inhibitory effect on the formation of amyloid aggregates by L-ascorbic acid as well as enhanced amyloid aggregation by silver nanomaterials such as nanoparticles and nanowires. We believe that microwave technology has the potential to facilitate the study of amyloid aggregation in the presence of chemical agents or nanomaterials.

(Non) formation of methanol by direct hydrogenation of formate on copper catalysts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yang, Yong; Mims, Charles A.; Disselkamp, Robert S.

2010-10-14

We have attempted to hydrogenate adsorbed formate species on copper catalysts to probe the importance of this postulated mechanistic step in methanol synthesis. Surface formate coverages up to 0.25 were produced at temperatures between 413K and 453K on supported (Cu/SiO2) copper and unsupported copper catalysts. The adlayers were produced by various methods including (1) steady state catalytic conditions in CO2-H2 (3:1, 6 bar) atmospheres, and (2) by exposure of the catalysts to formic acid. As reported in earlier work, the catalytic surface at steady state contains bidentate formate species with coverages up to saturation levels of ~ 0.25 at themore » low temperatures of this study. The reactivity of these formate adlayers was investigated at relevant reaction temperatures in atmospheres containing up to 6 bar H2 partial pressure by simultaneous mass spectrometry (MS) and infrared (IR) spectroscopy measurements. The yield of methanol during the attempted hydrogenation (“titration”) of these adlayers was insignificant (<0.2 mol % of the formate adlayer) even in dry hydrogen partial pressures up to 6 bar. Hydrogen titration of formate species produced from formic acid also failed to produce significant quantities of methanol, and attempted titration in gases consisting of CO-hydrogen mixtures or dry CO2 were also unproductive. The formate decomposition kinetics, measured by IR, were also unaffected by these changes in the gas composition. Similar experiments on unsupported copper also failed to show any methanol. From these results, we conclude that methanol synthesis on copper cannot result from the direct hydrogenation of (bidentate) formate species in simple steps involving adsorbed H species alone. Furthermore, experiments performed on both supported (Cu/SiO2) and unsupported copper catalysts gave similar results implying that the methanol synthesis reaction mechanism only involves metal surface chemistry. Pre-exposure of the bidentate formate adlayer to

The positron peak puzzle - Recent results from APEX

DOE PAGES

Ahmad, I; Austin, SM; Back, BB; ...

1996-01-01

Results are presented from a new experiment, APEX, designed to study the previously reported sharp lines in sum-energy spectra of positrons and electrons produced in collisions of very heavy ions. Data have been collected for 238U + 181Ta and 238U + 232Th. No evidence is found for narrow structures similar to those previously reported. For the specific case of the isolated decay of a neutral particle of mass 1.4–2.1 MeV/c 2, the upper limits on cross sections obtained are significantly less than previously reported. Data are also presented for internal pair conversion in 206Pb. These results are used to setmore » limits for the possible contribution to the pair yield of a 1780 keV transition in 238U observed in heavy-ion gamma-ray coincidence measurements.« less

Galaxy and mass assembly (GAMA): dust obscuration in galaxies and their recent star formation histories

NASA Astrophysics Data System (ADS)

Wijesinghe, D. B.; Hopkins, A. M.; Sharp, R.; Gunawardhana, M.; Brough, S.; Sadler, E. M.; Driver, S.; Baldry, I.; Bamford, S.; Liske, J.; Loveday, J.; Norberg, P.; Peacock, J.; Popescu, C. C.; Tuffs, R. J.; Bland-Hawthorn, J.; Cameron, E.; Croom, S.; Frenk, C.; Hill, D.; Jones, D. H.; van Kampen, E.; Kelvin, L.; Kuijken, K.; Madore, B.; Nichol, B.; Parkinson, H.; Pimbblet, K. A.; Prescott, M.; Robotham, A. S. G.; Seibert, M.; Simmat, E.; Sutherland, W.; Taylor, E.; Thomas, D.

2011-02-01

We present self-consistent star formation rates derived through pan-spectral analysis of galaxies drawn from the Galaxy and Mass Assembly (GAMA) survey. We determine the most appropriate form of dust obscuration correction via application of a range of extinction laws drawn from the literature as applied to Hα, [O II] and UV luminosities. These corrections are applied to a sample of 31 508 galaxies from the GAMA survey at z < 0.35. We consider several different obscuration curves, including those of Milky Way, Calzetti and Fischera & Dopita curves and their effects on the observed luminosities. At the core of this technique is the observed Balmer decrement, and we provide a prescription to apply optimal obscuration corrections using the Balmer decrement. We carry out an analysis of the star formation history (SFH) using stellar population synthesis tools to investigate the evolutionary history of our sample of galaxies as well as to understand the effects of variation in the initial mass function (IMF) and the effects this has on the evolutionary history of galaxies. We find that the Fischera & Dopita obscuration curve with an Rv value of 4.5 gives the best agreement between the different SFR indicators. The 2200 Å feature needed to be removed from this curve to obtain complete consistency between all SFR indicators suggesting that this feature may not be common in the average integrated attenuation of galaxy emission. We also find that the UV dust obscuration is strongly dependent on the SFR.

Connecting the Cosmic Star Formation Rate with the Local Star Formation

NASA Astrophysics Data System (ADS)

Gribel, Carolina; Miranda, Oswaldo D.; Williams Vilas-Boas, José

2017-11-01

We present a model that unifies the cosmic star formation rate (CSFR), obtained through the hierarchical structure formation scenario, with the (Galactic) local star formation rate (SFR). It is possible to use the SFR to generate a CSFR mapping through the density probability distribution functions commonly used to study the role of turbulence in the star-forming regions of the Galaxy. We obtain a consistent mapping from redshift z˜ 20 up to the present (z = 0). Our results show that the turbulence exhibits a dual character, providing high values for the star formation efficiency (< \\varepsilon > ˜ 0.32) in the redshift interval z˜ 3.5{--}20 and reducing its value to < \\varepsilon > =0.021 at z = 0. The value of the Mach number ({{ M }}{crit}), from which < \\varepsilon > rapidly decreases, is dependent on both the polytropic index (Γ) and the minimum density contrast of the gas. We also derive Larson’s first law associated with the velocity dispersion (< {V}{rms}> ) in the local star formation regions. Our model shows good agreement with Larson’s law in the ˜ 10{--}50 {pc} range, providing typical temperatures {T}0˜ 10{--}80 {{K}} for the gas associated with star formation. As a consequence, dark matter halos of great mass could contain a number of halos of much smaller mass, and be able to form structures similar to globular clusters. Thus, Larson’s law emerges as a result of the very formation of large-scale structures, which in turn would allow the formation of galactic systems, including our Galaxy.

Initial Satellite Formation Flight Results from the Magnetospheric Multiscale Mission

NASA Technical Reports Server (NTRS)

Williams, Trevor; Ottenstein, Neil; Palmer, Eric; Farahmand, Mitra

2016-01-01

This paper will describe the results that have been obtained to date concerning MMS formation flying. The MMS spacecraft spin at a rate of 3.1 RPM, with spin axis roughly aligned with Ecliptic North. Several booms are used to deploy instruments: two 5 m magnetometer booms in the spin plane, two rigid booms of length 12.5 m along the positive and negative spin axes, and four flexible wire booms of length 60 m in the spin plane. Minimizing flexible motion of the wire booms requires that reorientation of the spacecraft spin axis be kept to a minimum: this is limited to attitude maneuvers to counteract the effects of gravity-gradient and apparent solar motion. Orbital maneuvers must therefore be carried out in essentially the nominal science attitude. These burns make use of a set of monopropellant hydrazine thrusters: two (of thrust 4.5 N) along the spin axis in each direction, and eight (of thrust 18 N) in the spin plane; the latter are pulsed at the spin rate to produce a net delta-v. An on-board accelerometer-based controller is used to accurately generate a commanded delta-v. Navigation makes use of a weak-signal GPS-based system: this allows signals to be received even when MMS is flying above the GPS orbits, producing a highly accurate determination of the four MMS orbits. This data is downlinked to the MMS Mission Operations Center (MOC) and used by the MOC Flight Dynamics Operations Area (FDOA) for maneuver design. These commands are then uplinked to the spacecraft and executed autonomously using the controller, with the ground monitoring the burns in real time.

Improving quality of reproductive health care in Senegal through formative supervision: results from four districts

PubMed Central

Suh, Siri; Moreira, Philippe; Ly, Moussa

2007-01-01

Background In Senegal, traditional supervision often focuses more on collection of service statistics than on evaluation of service quality. This approach yields limited information on quality of care and does little to improve providers' competence. In response to this challenge, Management Sciences for Health (MSH) has implemented a program of formative supervision. This multifaceted, problem-solving approach collects data on quality of care, improves technical competence, and engages the community in improving reproductive health care. Methods This study evaluated changes in service quality and community involvement after two rounds of supervision in 45 health facilities in four districts of Senegal. We used checklists to assess quality in four areas of service delivery: infrastructure, staff and services management, record-keeping, and technical competence. We also measured community involvement in improving service quality using the completion rates of action plans. Results The most notable improvement across regions was in infection prevention. Management of staff, services, and logistics also consistently improved across the four districts. Record-keeping skills showed variable but lower improvement by region. The completion rates of action plans suggest that communities are engaged in improving service quality in all four districts. Conclusion Formative supervision can improve the quality of reproductive health services, especially in areas where there is on-site skill building and refresher training. This approach can also mobilize communities to participate in improving service quality. PMID:18047678

Enamel formation and amelogenesis imperfecta.

PubMed

Hu, Jan C-C; Chun, Yong-Hee P; Al Hazzazzi, Turki; Simmer, James P

2007-01-01

Dental enamel is the epithelial-derived hard tissue covering the crowns of teeth. It is the most highly mineralized and hardest tissue in the body. Dental enamel is acellular and has no physiological means of repair outside of the protective and remineralization potential provided by saliva. Enamel is comprised of highly organized hydroxyapatite crystals that form in a defined extracellular space, the contents of which are supplied and regulated by ameloblasts. The entire process is under genetic instruction. The genetic control of amelogenesis is poorly understood, but requires the activities of multiple components that are uniquely important for dental enamel formation. Amelogenesis imperfecta (AI) is a collective designation for the variety of inherited conditions displaying isolated enamel malformations, but the designation is also used to indicate the presence of an enamel phenotype in syndromes. Recently, genetic studies have demonstrated the importance of genes encoding enamel matrix proteins in the etiology of isolated AI. Here we review the essential elements of dental enamel formation and the results of genetic analyses that have identified disease-causing mutations in genes encoding enamel matrix proteins. In addition, we provide a fresh perspective on the roles matrix proteins play in catalyzing the biomineralization of dental enamel. Copyright 2007 S. Karger AG, Basel.

The heat of formation of gaseous PuO(2)2+ from relativistic density functional calculations.

PubMed

Moskaleva, Lyudmila V; Matveev, Alexei V; Dengler, Joachim; Rösch, Notker

2006-08-28

Using a set of model reactions, we estimated the heat of formation of gaseous PuO2(2+) from quantum-chemical reaction enthalpies and experimental heats of formation of reference species. To this end, we carried out relativistic density functional calculations on the molecules PuO(2)2+, PuO2, PuF6, and PuF4. We used a revised variant (PBEN) of the Perdew-Burke-Ernzerhof gradient-corrected exchange-correlation functional, and we accounted for spin-orbit interaction in a self-consistent fashion. As open-shell Pu species with two or more unpaired 5f electrons are involved, spin-orbit interaction significantly affects the energies of the model reactions. Our theoretical estimate for the heat of formation DeltafH degree 0(PuO2(2+),g), 418+/-15 kcal mol-1, evaluated using plutonium fluorides as references, is in good agreement with a recent experimental result, 413+/-16 kcal mol-1. The theoretical value connected to the experimental heat of formation of PuO2(g) has a notably higher uncertainty and therefore was not included in the final result.

Effect of Formative and Ability Test Results on Early Learning of Students

ERIC Educational Resources Information Center

Kadir, Abdul; Ardi, Muhammad; Nurhayati, B.; Dirawan, Gufran Darma

2016-01-01

The objective of this study was to examine the relationship of formative tests to early learning ability of students in the science learning style. This research used an experimental method with a 2 x 2 factorial design. The participants comprised all the students in class VII of the Islamic Junior High School State of Kolaka, a total of 343…

Predictions from star formation in the multiverse

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bousso, Raphael; Leichenauer, Stefan

2010-03-15

We compute trivariate probability distributions in the landscape, scanning simultaneously over the cosmological constant, the primordial density contrast, and spatial curvature. We consider two different measures for regulating the divergences of eternal inflation, and three different models for observers. In one model, observers are assumed to arise in proportion to the entropy produced by stars; in the others, they arise at a fixed time (5 or 10x10{sup 9} years) after star formation. The star formation rate, which underlies all our observer models, depends sensitively on the three scanning parameters. We employ a recently developed model of star formation in themore » multiverse, a considerable refinement over previous treatments of the astrophysical and cosmological properties of different pocket universes. For each combination of observer model and measure, we display all single and bivariate probability distributions, both with the remaining parameter(s) held fixed and marginalized. Our results depend only weakly on the observer model but more strongly on the measure. Using the causal diamond measure, the observed parameter values (or bounds) lie within the central 2{sigma} of nearly all probability distributions we compute, and always within 3{sigma}. This success is encouraging and rather nontrivial, considering the large size and dimension of the parameter space. The causal patch measure gives similar results as long as curvature is negligible. If curvature dominates, the causal patch leads to a novel runaway: it prefers a negative value of the cosmological constant, with the smallest magnitude available in the landscape.« less

Recent Developments of the GLIMS Glacier Database

NASA Astrophysics Data System (ADS)

Raup, B. H.; Berthier, E.; Bolch, T.; Kargel, J. S.; Paul, F.; Racoviteanu, A.

2017-12-01

Earth's glaciers are shrinking almost without exception, leading to changes in water resources, timing of runoff, sea level, and hazard potential. Repeat mapping of glacier outlines, lakes, and glacier topography, along with glacial processes, is critically needed to understand how glaciers will react to a changing climate, and how those changes will impact humans. To understand the impacts and processes behind the observed changes, it is crucial to monitor glaciers through time by mapping their areal extent, snow lines, ice flow velocities, associated water bodies, and thickness changes. The glacier database of the Global Land Ice Measurements from Space (GLIMS) initiative is the only multi-temporal glacier database capable of tracking all these glacier measurements and providing them to the scientific community and broader public.Recent developments in GLIMS include improvements in the database and web applications and new activities in the international GLIMS community. The coverage of the GLIMS database has recently grown geographically and temporally by drawing on the Randolph Glacier Inventory (RGI) and other new data sets. The GLIMS database is globally complete, and approximately one third of glaciers have outlines from more than one time. New tools for visualizing and downloading GLIMS data in a choice of formats and data models have been developed, and a new data model for handling multiple glacier records through time while avoiding double-counting of glacier number or area is nearing completion. A GLIMS workshop was held in Boulder, Colorado this year to facilitate two-way communication with the greater community on future needs.The result of this work is a more complete and accurate glacier data repository that shows both the current state of glaciers on Earth and how they have changed in recent decades. Needs for future scientific and technical developments were identified and prioritized at the GLIMS Workshop, and are reported here.

Mathematical study on robust tissue pattern formation in growing epididymal tubule.

PubMed

Hirashima, Tsuyoshi

2016-10-21

Tissue pattern formation during development is a reproducible morphogenetic process organized by a series of kinetic cellular activities, leading to the building of functional and stable organs. Recent studies focusing on mechanical aspects have revealed physical mechanisms on how the cellular activities contribute to the formation of reproducible tissue patterns; however, the understanding for what factors achieve the reproducibility of such patterning and how it occurs is far from complete. Here, I focus on a tube pattern formation during murine epididymal development, and show that two factors influencing physical design for the patterning, the proliferative zone within the tubule and the viscosity of tissues surrounding to the tubule, control the reproducibility of epididymal tubule pattern, using a mathematical model based on experimental data. Extensive numerical simulation of the simple mathematical model revealed that a spatially localized proliferative zone within the tubule, observed in experiments, results in more reproducible tubule pattern. Moreover, I found that the viscosity of tissues surrounding to the tubule imposes a trade-off regarding pattern reproducibility and spatial accuracy relating to the region where the tubule pattern is formed. This indicates an existence of optimality in material properties of tissues for the robust patterning of epididymal tubule. The results obtained by numerical analysis based on experimental observations provide a general insight on how physical design realizes robust tissue pattern formation. Copyright © 2016 Elsevier Ltd. All rights reserved.

Formation of TRAPPIST-1

NASA Astrophysics Data System (ADS)

Ormel, C. W.; Liu, B.; Schoonenberg, D.

2017-09-01

We present a model for the formation of the recently-discovered TRAPPIST-1 planetary system. In our scenario planets form in the interior regions, by accretion of mm to cm-size particles (pebbles) that drifted from the outer disk. This scenario has several advantages: it connects to the observation that disks are made up of pebbles, it is efficient, it explains why the TRAPPIST-1 planets are ˜Earth mass, and it provides a rationale for the system's architecture.

Recent Results from the T2K Experiment

NASA Astrophysics Data System (ADS)

Abe, K.; Abgrall, N.; Aihara, H.; Akiri, T.; Andreopoulos, C.; Aoki, S.; Ariga, A.; Ariga, T.; Assylbekov, S.; Autiero, D.; Barbi, M.; Barker, G. J.; Barr, G.; Bass, M.; Batkiewicz, M.; Bay, F.; Bentham, S. W.; Berardi, V.; Berger, B. E.; Berkman, S.; Bertram, I.; Bhadra, S.; Blaszczyk, F. D. M.; Blondel, A.; Bojechko, C.; Boyd, S. B.; Brailsford, D.; Bravar, A.; Bronner, C.; Buchanan, N.; Calland, R. G.; Caravaca Rodríguez, J.; Cartwright, S. L.; Castillo, R.; Catanesi, M. G.; Cervera, A.; Cherdack, D.; Christodoulou, G.; Clifton, A.; Coleman, J.; Coleman, S. J.; Collazuol, G.; Connolly, K.; Cremonesi, L.; Curioni, A.; Dabrowska, A.; Danko, I.; Das, R.; Davis, S.; de Perio, P.; De Rosa, G.; Dealtry, T.; Dennis, S. R.; Densham, C.; Di Lodovico, F.; Di Luise, S.; Drapier, O.; Duboyski, T.; Dufour, F.; Dumarchez, J.; Dytman, S.; Dziewiecki, M.; Emery, S.; Ereditato, A.; Escudero, L.; Finch, A. J.; Frank, E.; Friend, M.; Fujii, Y.; Fukuda, Y.; Furmanski, A. P.; Galymov, V.; Gaudin, A.; Giffin, S.; Giganti, C.; Gilje, K.; Golan, T.; Gomez-Cadenas, J. J.; Gonin, M.; Grant, N.; Gudin, D.; Hadley, D. R.; Haesler, A.; Haigh, M. D.; Hamilton, P.; Hansen, D.; Hara, T.; Hartz, M.; Hasegawa, T.; Hastings, N. C.; Hayato, Y.; Hearty, C.; Helmer, R. L.; Hierholzer, M.; Hignight, J.; Hillairet, A.; Himmel, A.; Hiraki, T.; Hirota, S.; Holeczek, J.; Horikawa, S.; Huang, K.; Ichikawa, A. K.; Ieki, K.; Ieva, M.; Ikeda, M.; Imber, J.; Insler, J.; Irvine, T. J.; Ishida, T.; Ishii, T.; Ives, S. J.; Iyogi, K.; Izmaylov, A.; Jacob, A.; Jamieson, B.; Johnson, R. A.; Jo, J. H.; Jonsson, P.; Joo, K. K.; Jung, C. K.; Kaboth, A. C.; Kajita, T.; Kakuno, H.; Kameda, J.; Kanazawa, Y.; Karlen, D.; Karpikov, I.; Kearns, E.; Khabibullin, M.; Khotjantsev, A.; Kielczewska, D.; Kikawa, T.; Kilinski, A.; Kim, J.; Kim, S. B.; Kisiel, J.; Kitching, P.; Kobayashi, T.; Kogan, G.; Kolaceke, A.; Konaka, A.; Kormos, L. L.; Korzenev, A.; Koseki, K.; Koshio, Y.; Kreslo, I.; Kropp, W.; Kubo, H.; Kudenko, Y.; Kumaratunga, S.; Kurjata, R.; Kutter, T.; Lagoda, J.; Laihem, K.; Laveder, M.; Lawe, M.; Lazos, M.; Lee, K. P.; Licciardi, C.; Lim, I. T.; Lindner, T.; Lister, C.; Litchfield, R. P.; Longhin, A.; Lopez, G. D.; Ludovici, L.; Macaire, M.; Magaletti, L.; Mahn, K.; Malek, M.; Manly, S.; Marino, A. D.; Marteau, J.; Martin, J. F.; Maruyama, T.; Marzec, J.; Masliah, P.; Mathie, E. L.; Matveev, V.; Mavrokoridis, K.; Mazzucato, E.; McCauley, N.; McFarland, K. S.; McGrew, C.; Metelko, C.; Mijakowski, P.; Miller, C. A.; Minamino, A.; Mineev, O.; Mine, S.; Missert, A.; Miura, M.; Monfregola, L.; Moriyama, S.; Mueller, Th. A.; Murakami, A.; Murdoch, M.; Murphy, S.; Myslik, J.; Nagasaki, T.; Nakadaira, T.; Nakahata, M.; Nakai, T.; Nakamura, K.; Nakayama, S.; Nakaya, T.; Nakayoshi, K.; Nielsen, C.; Nirkko, M.; Nishikawa, K.; Nishimura, Y.; O'Keeffe, H. M.; Ohta, R.; Okumura, K.; Okusawa, T.; Oryszczak, W.; Oser, S. M.; Otani, M.; Owen, R. A.; Oyama, Y.; Pac, M. Y.; Palladino, V.; Paolone, V.; Payne, D.; Pearce, G. F.; Perevozchikov, O.; Perkin, J. D.; Petrov, Y.; Pinzon Guerra, E. S.; Pistillo, C.; Plonski, P.; Poplawska, E.; Popov, B.; Posiadala, M.; Poutissou, J.-M.; Poutissou, R.; Przewlocki, P.; Quilain, B.; Radicioni, E.; Ratoff, P. N.; Ravonel, M.; Rayner, M. A. M.; Redij, A.; Reeves, M.; Reinherz-Aronis, E.; Retiere, F.; Robert, A.; Rodrigues, P. A.; Rondio, E.; Roth, S.; Rubbia, A.; Ruterbories, D.; Sacco, R.; Sakashita, K.; Sánchez, F.; Scantamburlo, E.; Scholberg, K.; Schwehr, J.; Scott, M.; Seiya, Y.; Sekiguchi, T.; Sekiya, H.; Sgalaberna, D.; Shiozawa, M.; Short, S.; Shustrov, Y.; Sinclair, P.; Smith, B.; Smith, R. J.; Smy, M.; Sobczyk, J. T.; Sobel, H.; Sorel, M.; Southwell, L.; Stamoulis, P.; Steinmann, J.; Still, B.; Suda, Y.; Suzuki, A.; Suzuki, K.; Suzuki, S. Y.; Suzuki, Y.; Szeglowski, T.; Tacik, R.; Tada, M.; Takahashi, S.; Takeda, A.; Takeuchi, Y.; Tanaka, H. A.; Tanaka, M. M.; Taylor, I. J.; Terhorst, D.; Terri, R.; Thompson, L. F.; Thorley, A.; Tobayama, S.; Toki, W.; Tomura, T.; Totsuka, Y.; Touramanis, C.; Tsukamoto, T.; Tzanov, M.; Uchida, Y.; Ueno, K.; Vacheret, A.; Vagins, M.; Vasseur, G.; Wachala, T.; Waldron, A. V.; Walter, C. W.; Wark, D.; Wascko, M. O.; Weber, A.; Wendell, R.; Wilkes, R. J.; Wilking, M. J.; Wilkinson, C.; Williamson, Z.; Wilson, J. R.; Wilson, R. J.; Wongjirad, T.; Yamada, Y.; Yamamoto, K.; Yanagisawa, C.; Yen, S.; Yershov, N.; Yokoyama, M.; Yuan, T.; Zalewska, A.; Zalipska, J.; Zambelli, L.; Zaremba, K.; Ziembicki, M.; Zimmerman, E. D.; Zito, M.; Żmuda, J.

2014-01-01

The Tokai to Kamioka (T2K) experiment studies neutrino oscillations using a beam of muon neutrinos produced by an accelerator. The neutrinos travel from J-PARC on the east coast of Japan and are detected 295 kilometers further away in the Super-Kamiokande detector. A complex of near detectors located 280 meters away from the neutrino production target is used to better characterize the neutrino beam and reduce systematic uncertainties. The experiment aims at measuring electronic neutrino appearance (νμ →νe oscillation) to measure the neutrino mixing angle θ13, and muon neutrino disappearance to measure the neutrino mixing angle θ23 and mass splitting | Δ m322 |. We report here electron neutrino appearance results using three years of data, recorded until the 2012 summer, as well as muon neutrino disappearance results based on the data coming from the first two years of the experiment.

Formation and Repair of Tobacco Carcinogen-Derived Bulky DNA Adducts

DOE PAGES

Hang, Bo

2010-01-01

DNA adducts play a central role in chemical carcinogenesis. The analysis of formation and repair of smoking-related DNA adducts remains particularly challenging as both smokers and nonsmokers exposed to smoke are repetitively under attack from complex mixtures of carcinogens such as polycyclic aromatic hydrocarbons and N -nitrosamines. The bulky DNA adducts, which usually have complex structure, are particularly important because of their biological relevance. Several known cellular DNA repair pathways have been known to operate in human cells on specific types of bulky DNA adducts, for example, nucleotide excision repair, base excision repair, and direct reversal involving O 6 -alkylguaninemore » DNA alkyltransferase or AlkB homologs. Understanding the mechanisms of adduct formation and repair processes is critical for the assessment of cancer risk resulting from exposure to cigarette smoke, and ultimately for developing strategies of cancer prevention. This paper highlights the recent progress made in the areas concerning formation and repair of bulky DNA adducts in the context of tobacco carcinogen-associated genotoxic and carcinogenic effects.« less

Formation control of robotic swarm using bounded artificial forces.

PubMed

Qin, Long; Zha, Yabing; Yin, Quanjun; Peng, Yong

2013-01-01

Formation control of multirobot systems has drawn significant attention in the recent years. This paper presents a potential field control algorithm, navigating a swarm of robots into a predefined 2D shape while avoiding intermember collisions. The algorithm applies in both stationary and moving targets formation. We define the bounded artificial forces in the form of exponential functions, so that the behavior of the swarm drove by the forces can be adjusted via selecting proper control parameters. The theoretical analysis of the swarm behavior proves the stability and convergence properties of the algorithm. We further make certain modifications upon the forces to improve the robustness of the swarm behavior in the presence of realistic implementation considerations. The considerations include obstacle avoidance, local minima, and deformation of the shape. Finally, detailed simulation results validate the efficiency of the proposed algorithm, and the direction of possible futrue work is discussed in the conclusions.

New Model for Agglutinitic Glass Formation from LSCC Data

NASA Technical Reports Server (NTRS)

Pieters, C. M.; Taylor, L. A.

2003-01-01

Since the return of the first lunar samples it has been well known that glass-welded aggregates (agglutinates) accumulate in lunar soil as the result of multiple processes, many of which are driven by micrometeorite impacts. The proportion of agglutinates increases with increasing exposure to the space environment, and for an individual soil the proportion of agglutinates also increases with decreasing particle size. Detailed chemical and petrographic analyses of a suite of mare soils and their agglutinate constituents prepared by the Lunar Soil Characterization Consortium appeared to confirm the "Fusion of the Finest Fraction" model for agglutinate formation (or F3) proposed by Papike et al. However, recent LSCC data for highland soils are not consistent with the F3 model and alternate models for agglutinate formation must be revisited. Instead, we suggest differential melting of soil species may be more consistent with the full range of soil data to date.

A Review of Recent Advances in Perioperative Patient Safety.

PubMed

Fowler, Alexander J

2013-01-01

Major complications in surgery affect up to 16% of surgical procedures. Over the past 50 years, many patient safety initiatives have attempted to reduce such complications. Since the formation of the National Patient Safety Agency in 2001, there have been major advances in patient safety. Most recently, the production and implementation of the Surgical Safety Checklist by the World Health Organisation (WHO), a checklist ensuring that certain 'never events' (wrong-site surgery, wrong operation etc.) do not occur, irrespective of healthcare allowance. In this review, a summary of recent advances in patient safety are considered - including improvements in communication, understanding of human factors that cause mistakes, and strategies developed to minimise these. Additionally, the synthesis of best medical practice and harm minimisation is examined, with particular emphasis on communication and appreciation of human factors in the operating theatre. This is based on the resource management systems developed in other high risk industries (e.g. nuclear), and has also been adopted for other high risk medical areas. The WHO global movement to reduce surgical mortality has been highly successful, especially in the healthcare systems of developing nations where mortality reductions of up to 50% have been observed, and reductions in patient complications of 4%. Incident reporting has long been a key component of patient safety and continues to be so; allowing reflection and improved guideline formation. All patients are placed at risk in the surgical environment. It is crucial that this risk is minimised, whilst optimising the patient's outcome. In this review, recent advances in perioperative patient safety are examined and placed in context.

Structural analysis of star-forming blue early-type galaxies. Merger-driven star formation in elliptical galaxies

NASA Astrophysics Data System (ADS)

George, Koshy

2017-02-01

Context. Star-forming blue early-type galaxies at low redshift can give insight to the stellar mass growth of L⋆ elliptical galaxies in the local Universe. Aims: We wish to understand the reason for star formation in these otherwise passively evolving red and dead stellar systems. The fuel for star formation can be acquired through recent accretion events such as mergers or flyby. The signatures of such events should be evident from a structural analysis of the galaxy image. Methods: We carried out structural analysis on SDSS r-band imaging data of 55 star-forming blue elliptical galaxies, derived the structural parameters, analysed the residuals from best-fit to surface brightness distribution, and constructed the galaxy scaling relations. Results: We found that star-forming blue early-type galaxies are bulge-dominated systems with axial ratio >0.5 and surface brightness profiles fitted by Sérsic profiles with index (n) mostly >2. Twenty-three galaxies are found to have n< 2; these could be hosting a disc component. The residual images of the 32 galaxy surface brightness profile fits show structural features indicative of recent interactions. The star-forming blue elliptical galaxies follow the Kormendy relation and show the characteristics of normal elliptical galaxies as far as structural analysis is concerned. There is a general trend for high-luminosity galaxies to display interaction signatures and high star formation rates. Conclusions: The star-forming population of blue early-type galaxies at low redshifts could be normal ellipticals that might have undergone a recent gas-rich minor merger event. The star formation in these galaxies will shut down once the recently acquired fuel is consumed, following which the galaxy will evolve to a normal early-type galaxy.

Exoplanetary Atmospheres-Chemistry, Formation Conditions, and Habitability.

PubMed

Madhusudhan, Nikku; Agúndez, Marcelino; Moses, Julianne I; Hu, Yongyun

2016-12-01

Characterizing the atmospheres of extrasolar planets is the new frontier in exoplanetary science. The last two decades of exoplanet discoveries have revealed that exoplanets are very common and extremely diverse in their orbital and bulk properties. We now enter a new era as we begin to investigate the chemical diversity of exoplanets, their atmospheric and interior processes, and their formation conditions. Recent developments in the field have led to unprecedented advancements in our understanding of atmospheric chemistry of exoplanets and the implications for their formation conditions. We review these developments in the present work. We review in detail the theory of atmospheric chemistry in all classes of exoplanets discovered to date, from highly irradiated gas giants, ice giants, and super-Earths, to directly imaged giant planets at large orbital separations. We then review the observational detections of chemical species in exoplanetary atmospheres of these various types using different methods, including transit spectroscopy, Doppler spectroscopy, and direct imaging. In addition to chemical detections, we discuss the advances in determining chemical abundances in these atmospheres and how such abundances are being used to constrain exoplanetary formation conditions and migration mechanisms. Finally, we review recent theoretical work on the atmospheres of habitable exoplanets, followed by a discussion of future outlook of the field.

Exoplanetary Atmospheres—Chemistry, Formation Conditions, and Habitability

PubMed Central

Agúndez, Marcelino; Moses, Julianne I; Hu, Yongyun

2016-01-01

Characterizing the atmospheres of extrasolar planets is the new frontier in exoplanetary science. The last two decades of exoplanet discoveries have revealed that exoplanets are very common and extremely diverse in their orbital and bulk properties. We now enter a new era as we begin to investigate the chemical diversity of exoplanets, their atmospheric and interior processes, and their formation conditions. Recent developments in the field have led to unprecedented advancements in our understanding of atmospheric chemistry of exoplanets and the implications for their formation conditions. We review these developments in the present work. We review in detail the theory of atmospheric chemistry in all classes of exoplanets discovered to date, from highly irradiated gas giants, ice giants, and super-Earths, to directly imaged giant planets at large orbital separations. We then review the observational detections of chemical species in exoplanetary atmospheres of these various types using different methods, including transit spectroscopy, Doppler spectroscopy, and direct imaging. In addition to chemical detections, we discuss the advances in determining chemical abundances in these atmospheres and how such abundances are being used to constrain exoplanetary formation conditions and migration mechanisms. Finally, we review recent theoretical work on the atmospheres of habitable exoplanets, followed by a discussion of future outlook of the field. PMID:28057962

Exoplanetary Atmospheres—Chemistry, Formation Conditions, and Habitability

NASA Astrophysics Data System (ADS)

Madhusudhan, Nikku; Agúndez, Marcelino; Moses, Julianne I.; Hu, Yongyun

2016-12-01

Characterizing the atmospheres of extrasolar planets is the new frontier in exoplanetary science. The last two decades of exoplanet discoveries have revealed that exoplanets are very common and extremely diverse in their orbital and bulk properties. We now enter a new era as we begin to investigate the chemical diversity of exoplanets, their atmospheric and interior processes, and their formation conditions. Recent developments in the field have led to unprecedented advancements in our understanding of atmospheric chemistry of exoplanets and the implications for their formation conditions. We review these developments in the present work. We review in detail the theory of atmospheric chemistry in all classes of exoplanets discovered to date, from highly irradiated gas giants, ice giants, and super-Earths, to directly imaged giant planets at large orbital separations. We then review the observational detections of chemical species in exoplanetary atmospheres of these various types using different methods, including transit spectroscopy, Doppler spectroscopy, and direct imaging. In addition to chemical detections, we discuss the advances in determining chemical abundances in these atmospheres and how such abundances are being used to constrain exoplanetary formation conditions and migration mechanisms. Finally, we review recent theoretical work on the atmospheres of habitable exoplanets, followed by a discussion of future outlook of the field.

Tech notes: Ongoing or planned hydro research, results of recent studies, and reviews of new books, publications, and software

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

Ongoing or planned hydro research, results of recent studies, and reviews of new books, publications, and software are covered. This month`s Tech Notes include: (1) a study linking development and reservoir silting in El Salvador, (2) publication of a guide for small hydro operatos, and (3) publication of a text outlining the development of hydroelectric power in Russia.

Recent Flight Results of the TRMM Kalman Filter

NASA Technical Reports Server (NTRS)

Andrews, Stephen F.; Bilanow, Stephen; Bauer, Frank (Technical Monitor)

2002-01-01

The Tropical Rainfall Measuring Mission (TRMM) spacecraft is a nadir pointing spacecraft that nominally controls the roll and pitch attitude based on the Earth Sensor Assembly (ESA) output. TRMM's nominal orbit altitude was 350 km, until raised to 402 km to prolong mission life. During the boost, the ESA experienced a decreasing signal to noise ratio, until sun interference at 393 km altitude made the ESA data unreliable for attitude determination. At that point, the backup attitude determination algorithm, an extended Kalman filter, was enabled. After the boost finished, TRMM reacquired its nadir-pointing attitude, and continued its mission. This paper will briefly discuss the boost and the decision to turn on the backup attitude determination algorithm. A description of the extended Kalman filter algorithm will be given. In addition, flight results from analyzing attitude data and the results of software changes made onboard TRMM will be discussed. Some lessons learned are presented.

Recent flight-test results of optical airdata techniques

NASA Technical Reports Server (NTRS)

Bogue, Rodney K.

1993-01-01

Optical techniques for measuring airdata parameters were demonstrated with promising results on high performance fighter aircraft. These systems can measure the airspeed vector, and some are not as dependent on special in-flight calibration processes as current systems. Optical concepts for measuring freestream static temperature and density are feasible for in-flight applications. The best feature of these concepts is that the air data measurements are obtained nonintrusively, and for the most part well into the freestream region of the flow field about the aircraft. Current requirements for measuring air data at high angle of attack, and future need to measure the same information at hypersonic flight conditions place strains on existing techniques. Optical technology advances show outstanding potential for application in future programs and promise to make common use of optical concepts a reality. Results from several flight-test programs are summarized, and the technology advances required to make optical airdata techniques practical are identified.

Mechanisms of plant spindle formation.

PubMed

Zhang, Han; Dawe, R Kelly

2011-04-01

In eukaryotes, the formation of a bipolar spindle is necessary for the equal segregation of chromosomes to daughter cells. Chromosomes, microtubules and kinetochores all contribute to spindle morphogenesis and have important roles during mitosis. A unique property of flowering plant cells is that they entirely lack centrosomes, which in animals have a major role in spindle formation. The absence of these important structures suggests that plants have evolved novel mechanisms to assure chromosome segregation. In this review, we highlight some of the recent studies on plant mitosis and argue that plants utilize a variation of "spindle self-organization" that takes advantage of the early polarity of plant cells and accentuates the role of kinetochores in stabilizing the spindle midzone in prometaphase.

AMR Studies of Star Formation: Simulations and Simulated Observations

NASA Astrophysics Data System (ADS)

Offner, Stella; McKee, C. F.; Klein, R. I.

2009-01-01

Molecular clouds are typically observed to be approximately virialized with gravitational and turbulent energy in balance, yielding a star formation rate of a few percent. The origin and characteristics of the observed supersonic turbulence are poorly understood, and without continued energy injection the turbulence is predicted to decay within a cloud dynamical time. Recent observations and analytic work have suggested a strong connection between the initial stellar mass function, the core mass function, and turbulence characteristics. The role of magnetic fields in determining core lifetimes, shapes, and kinematic properties remains hotly debated. Simulations are a formidable tool for studying the complex process of star formation and addressing these puzzles. I present my results modeling low-mass star formation using the ORION adaptive mesh refinement (AMR) code. I investigate the properties of forming cores and protostars in simulations in which the turbulence is driven to maintain virial balance and where it is allowed to decay. I will discuss simulated observations of cores in dust emission and in molecular tracers and compare to observations of local star-forming clouds. I will also present results from ORION cluster simulations including flux-limited diffusion radiative transfer and show that radiative feedback, even from low-mass stars, has a significant effect on core fragmentation, disk properties, and the IMF. Finally, I will discuss the new simulation frontier of AMR multigroup radiative transfer.

Data science implications in diamond formation and craton evolution

NASA Astrophysics Data System (ADS)

Pan, F.; Huang, F.; Fox, P. A.

2017-12-01

Diamonds are so-called "messengers" from the deep Earth. Fluid and mineral inclusions in diamonds could reflect the compositions of fluids/melts and wall-rocks in which diamond formed. Recently many diamond samples are examined to study the water content in the mantle transition zone1, the mechanism of diamond formation2 and the mantle evolution history3. However, most of the studies can only explain local activities. Therefore, an overall project of data grouping, comparison and correlation is needed, but limited progress has been made due to a lack of benchmark datasets on diamond formation and effective computing algorithms. In this study, we start by proposing the very first complete and easily-accessible dataset on mineral and fluid inclusions in diamonds. We rescue, collect and organize the data available from papers, journals and other publications resources ([2-4] and more), and then apply several state-of-the-art machine learning methods to tackle this earth science problem by clustering diamond formation process into distinct groups primarily based on the compositions, the formation temperature and pressure, the age and so on. Our ongoing work includes further data exploration and training existing models. Our preliminary results show that diamonds formed from older cratons usually have higher formation temperature. Also peridotitic diamonds take a much larger population than the ecologitic ones. More details are being discovered when we finish constructing the database and training our model. We expect the result to demonstrate the advantages of using machine learning and data science in earth science research problems. Our methodology for knowledge discovery are very general and can be broadly applied to other earth science research problems under the same framework.[1] Pearson et al, Nature (2014); [2] Tomlinson et al, EPSL (2006); [3] Weiss et al, Nature (2016); [4] Stachel and Harris, Ore Geology Reviews (2008); Weiss et al, EPSL (2013)

QuakeML: Recent Development and First Applications of the Community-Created Seismological Data Exchange Standard