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Sample records for fourier phase image

  1. Quantitative phase imaging via Fourier ptychographic microscopy

    PubMed Central

    Ou, Xiaoze; Horstmeyer, Roarke; Yang, Changhuei; Zheng, Guoan

    2014-01-01

    Fourier ptychographic microscopy (FPM) is a recently developed imaging modality that uses angularly varying illumination to extend a system’s performance beyond the limit defined by its optical components. The FPM technique applies a novel phase-retrieval procedure to achieve resolution enhancement and complex image recovery. In this Letter, we compare FPM data to theoretical prediction and phase-shifting digital holography measurement to show that its acquired phase maps are quantitative and artifact-free. We additionally explore the relationship between the achievable spatial and optical thickness resolution offered by a reconstructed FPM phase image. We conclude by demonstrating enhanced visualization and the collection of otherwise unobservable sample information using FPM’s quantitative phase. PMID:24322147

  2. Grid-Independent Compressive Imaging and Fourier Phase Retrieval

    ERIC Educational Resources Information Center

    Liao, Wenjing

    2013-01-01

    This dissertation is composed of two parts. In the first part techniques of band exclusion(BE) and local optimization(LO) are proposed to solve linear continuum inverse problems independently of the grid spacing. The second part is devoted to the Fourier phase retrieval problem. Many situations in optics, medical imaging and signal processing call…

  3. Optical Fourier techniques for medical image processing and phase contrast imaging.

    PubMed

    Yelleswarapu, Chandra S; Kothapalli, Sri-Rajasekhar; Rao, D V G L N

    2008-04-01

    This paper briefly reviews the basics of optical Fourier techniques (OFT) and applications for medical image processing as well as phase contrast imaging of live biological specimens. Enhancement of microcalcifications in a mammogram for early diagnosis of breast cancer is the main focus. Various spatial filtering techniques such as conventional 4f filtering using a spatial mask, photoinduced polarization rotation in photosensitive materials, Fourier holography, and nonlinear transmission characteristics of optical materials are discussed for processing mammograms. We also reviewed how the intensity dependent refractive index can be exploited as a phase filter for phase contrast imaging with a coherent source. This novel approach represents a significant advance in phase contrast microscopy. PMID:18458764

  4. Multiple-image encryption based on phase mask multiplexing in fractional Fourier transform domain.

    PubMed

    Liansheng, Sui; Meiting, Xin; Ailing, Tian

    2013-06-01

    A multiple-image encryption scheme is proposed based on the phase retrieval process and phase mask multiplexing in the fractional Fourier transform domain. First, each original gray-scale image is encoded into a phase only function by using the proposed phase retrieval process. Second, all the obtained phase functions are modulated into an interim, which is encrypted into the final ciphertext by using the fractional Fourier transform. From a plaintext image, a group of phase masks is generated in the encryption process. The corresponding decrypted image can be recovered from the ciphertext only with the correct phase mask group in the decryption process. Simulation results show that the proposed phase retrieval process has high convergence speed, and the encryption algorithm can avoid cross-talk; in addition, its encrypted capacity is considerably enhanced. PMID:23722815

  5. Double image encryption based on linear blend operation and random phase encoding in fractional Fourier domain

    NASA Astrophysics Data System (ADS)

    Wang, Qu; Guo, Qing; Zhou, Jinyun

    2012-10-01

    A novel method for double image encryption is proposed by using linear blend operation and double-random phase encoding (DRPE) in the fractional Fourier domain. In the linear blend operation, a random orthogonal matrix is defined to linearly recombined pixel values of two original images. The resultant blended images are employed to constitute a complex-valued image, which is encrypted into an encrypted image with stationary white distribution by the DRPE in the fractional Fourier domain. The primitive images can be exactly recovered by applying correct keys with fractional orders, random phase masks and random angle function that is used in linear blend operation. Numerical simulations demonstrate that the proposed scheme has considerably high security level and certain robustness against data loss and noise disturbance.

  6. Double image encryption based on random phase encoding in the fractional Fourier domain.

    PubMed

    Tao, Ran; Xin, Yi; Wang, Yue

    2007-11-26

    A novel image encryption method is proposed by utilizing random phase encoding in the fractional Fourier domain to encrypt two images into one encrypted image with stationary white distribution. By applying the correct keys which consist of the fractional orders, the random phase masks and the pixel scrambling operator, the two primary images can be recovered without cross-talk. The decryption process is robust against the loss of data. The phase-based image with a larger key space is more sensitive to keys and disturbances than the amplitude-based image. The pixel scrambling operation improves the quality of the decrypted image when noise perturbation occurs. The novel approach is verified by simulations. PMID:19550895

  7. Single-channel color image encryption using phase retrieve algorithm in fractional Fourier domain

    NASA Astrophysics Data System (ADS)

    Sui, Liansheng; Xin, Meiting; Tian, Ailing; Jin, Haiyan

    2013-12-01

    A single-channel color image encryption is proposed based on a phase retrieve algorithm and a two-coupled logistic map. Firstly, a gray scale image is constituted with three channels of the color image, and then permuted by a sequence of chaotic pairs generated by the two-coupled logistic map. Secondly, the permutation image is decomposed into three new components, where each component is encoded into a phase-only function in the fractional Fourier domain with a phase retrieve algorithm that is proposed based on the iterative fractional Fourier transform. Finally, an interim image is formed by the combination of these phase-only functions and encrypted into the final gray scale ciphertext with stationary white noise distribution by using chaotic diffusion, which has camouflage property to some extent. In the process of encryption and decryption, chaotic permutation and diffusion makes the resultant image nonlinear and disorder both in spatial domain and frequency domain, and the proposed phase iterative algorithm has faster convergent speed. Additionally, the encryption scheme enlarges the key space of the cryptosystem. Simulation results and security analysis verify the feasibility and effectiveness of this method.

  8. Color image encryption using iterative phase retrieve process in quaternion Fourier transform domain

    NASA Astrophysics Data System (ADS)

    Sui, Liansheng; Duan, Kuaikuai

    2015-02-01

    A single-channel color image encryption method is proposed based on iterative phase iterative process in quaternion Fourier transform domain. First, three components of the plain color image is confused respectively by using cat map. Second, the confused components are combined into a pure quaternion image, which is encode to the phase only function by using an iterative phase retrieval process. Finally, the phase only function is encrypted into the gray scale ciphertext with stationary white noise distribution based on the chaotic diffusion, which has camouflage property to some extent. The corresponding plain color image can be recovered from the ciphertext only with correct keys in the decryption process. Simulation results verify the feasibility and effectiveness of the proposed method.

  9. Fractional Fourier domain optical image hiding using phase retrieval algorithm based on iterative nonlinear double random phase encoding.

    PubMed

    Wang, Xiaogang; Chen, Wen; Chen, Xudong

    2014-09-22

    We present a novel image hiding method based on phase retrieval algorithm under the framework of nonlinear double random phase encoding in fractional Fourier domain. Two phase-only masks (POMs) are efficiently determined by using the phase retrieval algorithm, in which two cascaded phase-truncated fractional Fourier transforms (FrFTs) are involved. No undesired information disclosure, post-processing of the POMs or digital inverse computation appears in our proposed method. In order to achieve the reduction in key transmission, a modified image hiding method based on the modified phase retrieval algorithm and logistic map is further proposed in this paper, in which the fractional orders and the parameters with respect to the logistic map are regarded as encryption keys. Numerical results have demonstrated the feasibility and effectiveness of the proposed algorithms. PMID:25321769

  10. Fourier holographic display system of three-dimensional images using phase-only spatial light modulator

    NASA Astrophysics Data System (ADS)

    Zhang, Hao; Zhao, Yan; Gu, Huarong; Tan, Qiaofeng; Cao, Liangcai; Jin, Guofan

    2012-11-01

    We propose a holographic 3D display system which can produce images with adjustable viewing parameters and eliminated zero-order interruption. The 3D scene is generated from a 3D CAD tool, and point source algorithm is used to generate the holograms. A two-step model is introduced in the computing to generate precise Fourier holograms. A phase-only spatial light modulator (SLM) is used in the optical reconstruction, which can replay clear images for 3D diffusive objects. During optical reconstructing, the viewing angle and image size of the system can be adjusted by changing the parameters of the replay lens. A filter is introduced in the replay system to eliminate the zero-order interruption and increase the 3D image quality. Optical experiments are performed, and the results show that our proposed holographic display system can produce noiseless 3D image reconstructions.

  11. Superresolution imaging method using phase-shifting digital lensless Fourier holography.

    PubMed

    Granero, Luis; Micó, Vicente; Zalevsky, Zeev; García, Javier

    2009-08-17

    A method which is useful for obtaining superresolved imaging in a digital lensless Fourier holographic configuration is presented. By placing a diffraction grating between the input object and the CCD recording device, additional high-order spatial-frequency content of the object spectrum is directed towards the CCD. Unlike other similar methods, the recovery of the different band pass images is performed by inserting a reference beam in on-axis mode and using phase-shifting method. This strategy provides advantages concerning the usage of the whole frequency plane as imaging plane. Thus, the method is no longer limited by the zero order term and the twin image. Finally, the whole process results in a synthetic aperture generation that expands up the system cutoff frequency and yields a superresolution effect. Experimental results validate our concepts for a resolution improvement factor of 3. PMID:19687979

  12. Fourier plane imaging microscopy

    SciTech Connect

    Dominguez, Daniel Peralta, Luis Grave de; Alharbi, Nouf; Alhusain, Mdhaoui; Bernussi, Ayrton A.

    2014-09-14

    We show how the image of an unresolved photonic crystal can be reconstructed using a single Fourier plane (FP) image obtained with a second camera that was added to a traditional compound microscope. We discuss how Fourier plane imaging microscopy is an application of a remarkable property of the obtained FP images: they contain more information about the photonic crystals than the images recorded by the camera commonly placed at the real plane of the microscope. We argue that the experimental results support the hypothesis that surface waves, contributing to enhanced resolution abilities, were optically excited in the studied photonic crystals.

  13. Fourier phase in Fourier-domain optical coherence tomography

    PubMed Central

    Uttam, Shikhar; Liu, Yang

    2015-01-01

    Phase of an electromagnetic wave propagating through a sample-of-interest is well understood in the context of quantitative phase imaging in transmission-mode microscopy. In the past decade, Fourier-domain optical coherence tomography has been used to extend quantitative phase imaging to the reflection-mode. Unlike transmission-mode electromagnetic phase, however, the origin and characteristics of reflection-mode Fourier phase are poorly understood, especially in samples with a slowly varying refractive index. In this paper, the general theory of Fourier phase from first principles is presented, and it is shown that Fourier phase is a joint estimate of subresolution offset and mean spatial frequency of the coherence-gated sample refractive index. It is also shown that both spectral-domain phase microscopy and depth-resolved spatial-domain low-coherence quantitative phase microscopy are special cases of this general theory. Analytical expressions are provided for both, and simulations are presented to explain and support the theoretical results. These results are further used to show how Fourier phase allows the estimation of an axial mean spatial frequency profile of the sample, along with depth-resolved characterization of localized optical density change and sample heterogeneity. Finally, a Fourier phase-based explanation of Doppler optical coherence tomography is also provided. PMID:26831383

  14. Simultaneous nonlinear encryption of grayscale and color images based on phase-truncated fractional Fourier transform and optical superposition principle.

    PubMed

    Wang, Xiaogang; Zhao, Daomu

    2013-09-01

    A nonlinear color and grayscale images cryptosystem based on phase-truncated fractional Fourier transform and optical superposition principle is proposed. In order to realize simultaneous encryption of color and grayscale images, each grayscale image is first converted into two phase masks by using an optical coherent superposition, one of which is treated as a part of input information that will be fractional Fourier transformed while the other in the form of a chaotic random phase mask (CRPM) is used as a decryption key. For the purpose of optical performance, all the processes are performed through three channels, i.e., red, green, and blue. Different from most asymmetric encryption methods, the decryption process is designed to be linear for the sake of effective decryption. The encryption level of a double random phase encryption based on phase-truncated Fourier transform is enhanced by extending it into fractional Fourier domain and the load of the keys management and transmission is lightened by using CRPMs. The security of the proposed cryptosystem is discussed and computer simulation results are presented to verify the validity of the proposed method. PMID:24085074

  15. Fourier plane image amplifier

    DOEpatents

    Hackel, L.A.; Hermann, M.R.; Dane, C.B.; Tiszauer, D.H.

    1995-12-12

    A solid state laser is frequency tripled to 0.3 {micro}m. A small portion of the laser is split off and generates a Stokes seed in a low power oscillator. The low power output passes through a mask with the appropriate hole pattern. Meanwhile, the bulk of the laser output is focused into a larger stimulated Brillouin scattering (SBS) amplifier. The low power beam is directed through the same cell in the opposite direction. The majority of the amplification takes place at the focus which is the fourier transform plane of the mask image. The small holes occupy large area at the focus and thus are preferentially amplified. The amplified output is now imaged onto the multichip module where the holes are drilled. Because of the fourier plane amplifier, only about 1/10th the power of a competitive system is needed. This concept allows less expensive masks to be used in the process and requires much less laser power. 1 fig.

  16. Fourier plane image amplifier

    DOEpatents

    Hackel, Lloyd A.; Hermann, Mark R.; Dane, C. Brent; Tiszauer, Detlev H.

    1995-01-01

    A solid state laser is frequency tripled to 0.3 .mu.m. A small portion of the laser is split off and generates a Stokes seed in a low power oscillator. The low power output passes through a mask with the appropriate hole pattern. Meanwhile, the bulk of the laser output is focused into a larger stimulated Brillouin scattering (SBS) amplifier. The low power beam is directed through the same cell in the opposite direction. The majority of the amplification takes place at the focus which is the fourier transform plane of the mask image. The small holes occupy large area at the focus and thus are preferentially amplified. The amplified output is now imaged onto the multichip module where the holes are drilled. Because of the fourier plane amplifier, only .about.1/10th the power of a competitive system is needed. This concept allows less expensive masks to be used in the process and requires much less laser power.

  17. Imaging Fourier Transform Spectrometer

    SciTech Connect

    Bennett, C.L.; Carter, M.R.; Fields, D.J.; Hernandez, J.

    1993-04-14

    The operating principles of an Imaging Fourier Transform Spectrometer (IFTS) are discussed. The advantages and disadvantages of such instruments with respect to alternative imaging spectrometers are discussed. The primary advantages of the IFTS are the capacity to acquire more than an order of magnitude more spectral channels than alternative systems with more than an order of magnitude greater etendue than for alternative systems. The primary disadvantage of IFTS, or FTS in general, is the sensitivity to temporal fluctuations, either random or periodic. Data from the IRIFTS (ir IFTS) prototype instrument, sensitive in the infrared, are presented having a spectral sensitivity of 0.01 absorbance units, a spectral resolution of 6 cm{sup {minus}1} over the range 0 to 7899 cm{sup {minus}1}, and a spatial resolution of 2.5 mr.

  18. Digital imaging of Giemsa-banded human chromosomes: eigenanalysis and the Fourier phase reconstruction

    NASA Astrophysics Data System (ADS)

    Jericevic, Zeljko; McGavran, Loris; Smith, Louis C.

    1991-05-01

    The new methodology of chromosome analysis based on eigenanalysis and iterative Fourier synthesis has been developed. The approach is inspired by the analysis developed in electron microscopy of particles, and has been modified to address particular problems of chromosome analysis. Preliminary results on data sets containing 40-80 images for each of the human chromosomes indicate that this methodology provides an improvement of chromosome band resolution and potentially can provide cytogeneticist with some new insights. The proposed procedure is a novel approach in chromosome analysis and represents a significant contribution to quantitative cytogenetics. It opens the possibility of identifying defects in chromosome banding pattern automatically.

  19. A higher dimensional homodyne filter for phase sensitive partial Fourier reconstruction of magnetic resonance imaging.

    PubMed

    Paul, Joseph Suresh; Krishna Swamy Pillai, Uma

    2015-11-01

    The aim of this paper is to introduce procedural steps for extension of the 1D homodyne phase correction for k-space truncation in all gradient encoding directions. Compared to the existing method applied to 2D partial k-space, signal losses introduced by the phase correction filter are observed to be minimal for the modified approach. In addition, the modified form of phase correction retains the inherent property of homodyne filtering for elimination of incidental phase artifacts due to truncation. In parallel imaging, this new form of homodyne filtering is shown to be effective for minimizing the signal losses, when each of the channel k-spaces is truncated along both phase and frequency-encode directions. This is illustrated with 2D partial k-space for flow compensated multichannel susceptibility weighted imaging. Extension of this method to 3D partial k-space shows improved reconstruction of flow information in phase contrast magnetic resonance angiography with reduced blur and enhanced background suppression. PMID:26117692

  20. Electro-optic imaging Fourier transform spectrometer

    NASA Technical Reports Server (NTRS)

    Chao, Tien-Hsin (Inventor); Znod, Hanying (Inventor)

    2009-01-01

    An Electro-Optic Imaging Fourier Transform Spectrometer (EOIFTS) for Hyperspectral Imaging is described. The EOIFTS includes an input polarizer, an output polarizer, and a plurality of birefringent phase elements. The relative orientations of the polarizers and birefringent phase elements can be changed mechanically or via a controller, using ferroelectric liquid crystals, to substantially measure the spectral Fourier components of light propagating through the EIOFTS. When achromatic switches are used as an integral part of the birefringent phase elements, the EIOFTS becomes suitable for broadband applications, with over 1 micron infrared bandwidth.

  1. Electro-optic Imaging Fourier Transform Spectrometer

    NASA Technical Reports Server (NTRS)

    Chao, Tien-Hsin

    2005-01-01

    JPL is developing an innovative compact, low mass, Electro-Optic Imaging Fourier Transform Spectrometer (E-O IFTS) for hyperspectral imaging applications. The spectral region of this spectrometer will be 1 - 2.5 micron (1000-4000/cm) to allow high-resolution, high-speed hyperspectral imaging applications. One application will be the remote sensing of the measurement of a large number of different atmospheric gases simultaneously in the same airmass. Due to the use of a combination of birefringent phase retarders and multiple achromatic phase switches to achieve phase delay, this spectrometer is capable of hyperspectral measurements similar to that of the conventional Fourier transform spectrometer but without any moving parts. In this paper, the principle of operations, system architecture and recent experimental progress will be presented.

  2. Electro-optic Imaging Fourier Transform Spectrometer

    NASA Technical Reports Server (NTRS)

    Chao, Tien-Hsin

    2005-01-01

    JPL is developing an innovative compact, low mass, Electro-Optic Imaging Fourier Transform Spectrometer (E-0IFTS) for hyperspectral imaging applications. The spectral region of this spectrometer will be 1 - 2.5 pm (1000 -4000 cm-') to allow high-resolution, high-speed hyperspectral imaging applications [l-51. One application will be theremote sensing of the measurement of a large number of different atmospheric gases simultaneously in the sameairmass. Due to the use of a combination of birefiingent phase retarders and multiple achromatic phase switches toachieve phase delay, this spectrometer is capable of hyperspectral measurements similar to that of the conventionalFourier transform spectrometer but without any moving parts. In this paper, the principle of operations, systemarchitecture and recent experimental progress will be presen.

  3. Fourier phase microscopy with white light

    PubMed Central

    Bhaduri, Basanta; Tangella, Krishnarao; Popescu, Gabriel

    2013-01-01

    Laser-based Fourier phase microscopy (FPM) works on the principle of decomposition of an image field in two spatial components that can be controllably shifted in phase with respect to each other. However, due to the coherent illumination, the contrast in phase images is degraded by speckles. In this paper we present FPM with spatially coherent white light (wFPM), which offers high spatial phase sensitivity due to the low temporal coherence and high temporal phase stability due to common path geometry. Further, by using a fast spatial light modulator (SLM) and a fast scientific-grade complementary metal oxide semiconductor (sCMOS) camera, we report imaging at a maximum rate of 12.5 quantitative phase frames per second with 5.5 mega pixels image size. We illustrate the utility of wFPM as a contrast enhancement as well as dynamic phase measurement method by imaging section of benign colonic glands and red blood cell membrane fluctuation. PMID:24010005

  4. Laser Field Imaging Through Fourier Transform Heterodyne

    SciTech Connect

    Cooke, B.J.; Laubscher, B.E.; Olivas, N.L.; Galbraith, A.E.; Strauss, C.E.; Grubler, A.C.

    1999-04-05

    The authors present a detection process capable of directly imaging the transverse amplitude, phase, and Doppler shift of coherent electromagnetic fields. Based on coherent detection principles governing conventional heterodyned RADAR/LADAR systems, Fourier Transform Heterodyne incorporates transverse spatial encoding of the reference local oscillator for image capture. Appropriate selection of spatial encoding functions allows image retrieval by way of classic Fourier manipulations. Of practical interest: (1) imaging may be accomplished with a single element detector/sensor requiring no additional scanning or moving components, (2) as detection is governed by heterodyne principles, near quantum limited performance is achievable, (3) a wide variety of appropriate spatial encoding functions exist that may be adaptively configured in real-time for applications requiring optimal detection, and (4) the concept is general with the applicable electromagnetic spectrum encompassing the RF through optical.

  5. Fourier transform based scalable image quality measure.

    PubMed

    Narwaria, Manish; Lin, Weisi; McLoughlin, Ian; Emmanuel, Sabu; Chia, Liang-Tien

    2012-08-01

    We present a new image quality assessment (IQA) algorithm based on the phase and magnitude of the 2D (twodimensional) Discrete Fourier Transform (DFT). The basic idea is to compare the phase and magnitude of the reference and distorted images to compute the quality score. However, it is well known that the Human Visual Systems (HVSs) sensitivity to different frequency components is not the same. We accommodate this fact via a simple yet effective strategy of nonuniform binning of the frequency components. This process also leads to reduced space representation of the image thereby enabling the reduced-reference (RR) prospects of the proposed scheme. We employ linear regression to integrate the effects of the changes in phase and magnitude. In this way, the required weights are determined via proper training and hence more convincing and effective. Lastly, using the fact that phase usually conveys more information than magnitude, we use only the phase for RR quality assessment. This provides the crucial advantage of further reduction in the required amount of reference image information. The proposed method is therefore further scalable for RR scenarios. We report extensive experimental results using a total of 9 publicly available databases: 7 image (with a total of 3832 distorted images with diverse distortions) and 2 video databases (totally 228 distorted videos). These show that the proposed method is overall better than several of the existing fullreference (FR) algorithms and two RR algorithms. Additionally, there is a graceful degradation in prediction performance as the amount of reference image information is reduced thereby confirming its scalability prospects. To enable comparisons and future study, a Matlab implementation of the proposed algorithm is available at http://www.ntu.edu.sg/home/wslin/reduced_phase.rar. PMID:22562758

  6. Double-image encryption without information disclosure using phase-truncation Fourier transforms and a random amplitude mask.

    PubMed

    Wang, Xiaogang; Zhao, Daomu; Chen, Yixiang

    2014-08-10

    We present a study about information disclosure in phase-truncation-based cryptosystems. The main information of the original image to be encoded can be obtained by using a decryption key in the worst case. The problem cannot be thoroughly solved by imaginary part truncating, keeping the encryption keys as private keys, or applying different phase keys for different plaintexts during each encryption process as well as the phase modulation in the frequency domain. In order to eliminate the risk of unintended information disclosure, we further propose a nonlinear spatial and spectral encoding technique using a random amplitude mask (RAM). The encryption process involving two security layers can be fully controlled by a RAM. The spatial encoding of the plaintext images and the simultaneous encryption of the plaintext images and the encryption key greatly enhance the security of system, avoiding several attacks that have cracked the phase-truncation-based cryptosystems. Besides, the hybrid encryption system retains the advantage of a trap door one-way function of phase truncation. Numerical results have demonstrated the feasibility and effectiveness of the proposed encryption algorithm. PMID:25320917

  7. Imaging vibration of the cochlear partition of an excised guinea pig cochlea using phase-sensitive Fourier domain optical coherence tomography

    NASA Astrophysics Data System (ADS)

    Choudhury, Niloy; Zeng, Yaguang; Fridberger, Anders; Chen, Fangyi; Zha, Dingjun; Nuttall, Alfred L.; Wang, Ruikang K.

    2011-03-01

    Studying the sound stimulated vibrations of various membranes that form the complex structure of the organ of Corti in the cochlea of the inner ear is essential for understanding how the travelling sound wave of the basilar membrane couples its energy to the organ structures. In this paper we report the feasibility of using phase-sensitive Fourier domain optical coherence tomography (FD-OCT) to image the vibration of various micro-structures of the cochlea at the same time. An excised cochlea of a guinea pig was stimulated using sounds at various frequencies and vibration image was obtained. When measuring the apex area, vibration signal from different turns, which have different best response frequencies are obtained in the same image. The method has the potential to measure the response from a much wider region of the cochlea than any other currently used method. The noise floor for vibration image for the system at 200 Hz was ~0.3nm.

  8. Rotational-translational fourier imaging system

    NASA Technical Reports Server (NTRS)

    Campbell, Jonathan W. (Inventor)

    2004-01-01

    This invention has the ability to create Fourier-based images with only two grid pairs. The two grid pairs are manipulated in a manner that allows (1) a first grid pair to provide multiple real components of the Fourier-based image and (2) a second grid pair to provide multiple imaginary components of the Fourier-based image. The novelty of this invention resides in the use of only two grid pairs to provide the same imaging information that has been traditionally collected with multiple grid pairs.

  9. PHASE RETRIEVAL FROM TWO DEFOCUSED IMAGES BY THE TRANSPORT OF INTENSITY EQUATION FORMALISM WITH FAST FOURIER TRANSFORM.

    SciTech Connect

    VOLKOV,V.V.; ZHU,Y.

    2001-08-05

    The problem of phase retrieval from intensity measurements plays an important role in many fields of physical research, e.g. optics, electron and x-ray microscopy, crystallography, diffraction tomography and others. In practice the recorded images contain information only on the intensity distribution I(x,y) = {Psi}*{Psi} = {vert_bar}A{vert_bar}{sup 2} of the imaging wave function {Psi} = A*exp(-i{var_phi}) and the phase information {var_phi}(x,y) is usually lost. In general, the phase problem can be solved either by special holographic/interferometric methods, or by non-interferometric approaches based on intensity measurements in far Fraunhofer zone or in the Fresnel zone at two adjacent planes orthogonal to the optical axis. The latter approach uses the transport-of-intensity equation (TIE) formalism, introduced originally by Teague [1] and developed later in [2]. Applications of TIE to nonmagnetic materials and magnetic inductance mapping were successfully made in [3,4]. However, this approach still needs further improvement both in mathematics and in practical solutions, since the result is very sensitive to many experimental parameters.

  10. Gas-phase plume from laser-irradiated fiberglass-reinforced polymers via imaging fourier transform spectroscopy.

    PubMed

    Acosta, Roberto I; Gross, Kevin C; Perram, Glen P; Johnson, Shane M; Dao, Ly; Medina, David F; Roybal, Robert; Black, Paul

    2014-01-01

    Emissive plumes from laser-irradiated fiberglass-reinforced polymers (FRP) were investigated using a mid-infrared imaging Fourier transform spectrometer, operating at fast framing rates (50 kHz imagery and 2.5 Hz hyperspectral imagery) with adequate spatial (0.81 mm(2) per pixel) and spectral resolution (2 cm(-1)). Fiberglass-reinforced polymer targets were irradiated with a 1064 nm continuous wave neodymium-doped yttrium aluminum garnet (Nd:YAG) laser for 60 s at 100 W in air. Strong emissions from H(2)O, CO, CO(2), and hydrocarbons were observed between 1800 and 5000 cm(-1). A single-layer radiative transfer model was developed for the spectral region from 2000 to 2400 cm(-1) to estimate spatial maps of temperature and column densities of CO and CO(2) from the hyperspectral imagery. The spectral model was used to compute the absorption cross sections of CO and CO(2) using spectral line parameters from the high-temperature extension of the HITRAN. The analysis of pre-combustion spectra yields effective temperatures rising from ambient to 1200 K and suddenly increasing to 1515 K upon combustion. The peak signal-to-noise ratio for a single spectrum exceeds 60:1, enabling temperature and column density determinations with low statistical error. For example, the spectral analysis for a single pixel within a single frame yields an effective temperature of 1019 6 K, and CO and CO(2) column densities of 1.14 0.05 and 1.11 0.03 10(18) molec/cm(2), respectively. Systematic errors associated with the radiative transfer model dominate, yielding effective temperatures with uncertainties of >100 K and column densities to within a factor of 2-3. Hydrocarbon emission at 2800 to 3200 cm(-1) is well correlated with CO column density. PMID:25014838

  11. Double image encryption based on iterative fractional Fourier transform

    NASA Astrophysics Data System (ADS)

    Liu, Zhengjun; Liu, Shutian

    2007-07-01

    We present an image encryption algorithm to simultaneously encrypt two images into a single one as the amplitudes of fractional Fourier transform with different orders. From the encrypted image we can get two original images independently by fractional Fourier transforms with two different fractional orders. This algorithm can be independent of additional random phases as the encryption/decryption keys. Numerical results are given to analyze the capability of this proposed method. A possible extension to multi-image encryption with a fractional order multiplexing scheme has also been given.

  12. Fourier analysis of quadratic phase interferograms

    NASA Astrophysics Data System (ADS)

    Muñoz-Maciel, Jesús; Mora-González, Miguel; Casillas-Rodríguez, Francisco J.; Peña-Lecona, Francisco G.

    2015-06-01

    A phase demodulation method from a single interferogram with a quadratic phase term is developed. The fringe pattern being analysed may contain circular, elliptic or astigmatic fringes. The Fourier transform of such interferograms is seen to be also a sine or a cosine of a second order polynomial in both the real and imaginary parts. In this work we take a discrete Fourier transform of the fringe patterns and then we take separate inverse discrete transforms of the real and imaginary parts of the frequency spectrum. This results in two new interferograms corresponding to the sine and cosine of the quadratic term of the phase modulated by the sine and cosine of the linear term. The linear term of these interferograms may be recovered with similar procedures of fringe analysis from open fringe interferograms. Once the linear term is retrieved the quadratic phase of the interferogram being analysed can also be calculated. The present approach is also being investigated for interferograms with nearly circularly symmetry given that the phase contains some tilt. The described procedure of Fourier analysis from quadratic phase interferograms of nearly symmetric interferograms could be used instead of complex and time consuming algorithms for phase recovery from fringe patterns with closed fringes. Finally, the method is tested in simulated and real data.

  13. Fourier Transform and Reflective Imaging Pyrometry

    SciTech Connect

    Stevens, G. D.

    2011-07-01

    A stationary Fourier transform pyrometer was used to record mid-wavelength IR spectra in dynamic shock experiments. The gated-IR camera used with this system was also used to record images of light produced and light reflected from shocked metals in order to constrain the dynamic emissivity and provide temperature estimates. This technique will be referred to as reflective imaging pyrometry.

  14. Livermore Imaging Fourier Transform Infrared Spectrometer (LIFTIRS)

    SciTech Connect

    Carter, M.R.; Bennett, C.L.; Fields, D.J.; Lee, F.D.

    1995-05-10

    Lawrence Livermore National Laboratory is currently operating a hyperspectral imager, the Livermore Imaging Fourier Transform Infrared Spectrometer (LIFTIRS). This instrument is capable of operating throughout the infrared spectrum from 3 to 12.5 {mu}m with controllable spectral resolution. In this presentation we report on it`s operating characteristics, current capabilities, data throughput and calibration issues.

  15. Proposal of snapshot line-imaging Fourier spectroscopy for smartphone

    NASA Astrophysics Data System (ADS)

    Kawashima, Natsumi; Sato, Shun; Ishida, Akane; Inohara, Daichi; Tanaka, Naotaka; Wada, Kenji; Nishiyama, Akira; Fujiwara, Masaru; Ishimaru, Ichiro

    2015-03-01

    We propose the extremely-compact-size line-imaging Fourier spectroscopy for smartphones. We realize the near common-path interferometer with strong robustness for mechanical vibrations by installing the transmission-type relative-inclined phase-shifter. The interferogram of an imaging line is formed as 2-dimensional fringe pattern on imaging sensor, such as CCD camera. In other words, the horizontal axis on an imaging sensor is assigned to phase-shift value. And the vertical axis is corresponds to image formation coordinate. Thus, by installing a relatively-inclined thin glass into imaging optics, such as smartphone, we will realize the line-imaging Fourier spectroscopy for healthcare sensor in daily-life environments.

  16. Gamma-ray imaging in Fourier space.

    PubMed

    Chou, C; Barrett, H H

    1978-11-01

    A new coded-aperture configuration for gamma-ray imaging is described. It measures a single Fourier component of the object distribution at a time and does not require a position-sensitive detector. If, however, a position-sensitive detector is used, three-dimensional information about the source can be obtained. PMID:19684741

  17. Coherent electromagnetic field imaging through Fourier transform heterodyne

    SciTech Connect

    Cooke, B.J.; Laubscher, B.E.; Olivas, N.L.; Goeller, R.M.; Cafferty, M.; Briles, S.D.; Galbraith, A.E. |; Grubler, A.C. |

    1998-12-31

    The authors present a detection process capable of directly imaging the transverse amplitude, phase, and if desired, Doppler shift of coherent electromagnetic fields. Based on coherent detection principles governing conventional heterodyned RADAR/LIDAR systems, Fourier Transform Heterodyne (FTH) incorporates transverse spatial encoding of the local oscillator for image capture. Appropriate selection of spatial encoding functions, or basis set, allows image retrieval by way of classic Fourier manipulations. Of practical interest: (1) imaging is accomplished on a single element detector requiring no additional scanning or moving components, and (2) a wide variety of appropriate spatial encoding functions exist that may be adaptively configured in real-time for applications requiring optimal detection. In this paper, they introduce the underlying principles governing FTH imaging, followed by demonstration of concept via a simple experimental setup based on a HeNe laser and a 69 element spatial phase modulator.

  18. Fourier analysis: from cloaking to imaging

    NASA Astrophysics Data System (ADS)

    Wu, Kedi; Cheng, Qiluan; Wang, Guo Ping

    2016-04-01

    Regarding invisibility cloaks as an optical imaging system, we present a Fourier approach to analytically unify both Pendry cloaks and complementary media-based invisibility cloaks into one kind of cloak. By synthesizing different transfer functions, we can construct different devices to realize a series of interesting functions such as hiding objects (events), creating illusions, and performing perfect imaging. In this article, we give a brief review on recent works of applying Fourier approach to analysis invisibility cloaks and optical imaging through scattering layers. We show that, to construct devices to conceal an object, no constructive materials with extreme properties are required, making most, if not all, of the above functions realizable by using naturally occurring materials. As instances, we experimentally verify a method of directionally hiding distant objects and create illusions by using all-dielectric materials, and further demonstrate a non-invasive method of imaging objects completely hidden by scattering layers.

  19. Triple image encryption scheme in fractional Fourier transform domains

    NASA Astrophysics Data System (ADS)

    Liu, Zhengjun; Dai, Jingmin; Sun, Xiaogang; Liu, Shutian

    2009-02-01

    We proposed a triple image encryption scheme by use of fractional Fourier transform. In this algorithm, an original image is encoded in amplitude part and other two images are encoded into phase information. The key of encryption algorithm is obtained from the difference between the third image and the output phase of transform. In general case, random phase encoding technology is not required in the proposed algorithm. Moreover, all information of images is preserved in theory when image are decrypted with correct key. The optical implementation of the algorithm is presented with an electro-optical hybrid structure. Numerical simulations have demonstrated the efficiency and the security of this algorithm. Based on this scheme a multiple image algorithm is expanded and designed.

  20. Fourier removal of stripe artifacts in IRAS images

    NASA Technical Reports Server (NTRS)

    Van Buren, Dave

    1987-01-01

    By working in the Fourier plane, approximate removal of stripe artifacts in IRAS images can be effected. The image of interest is smoothed and subtracted from the original, giving the high-spatial-frequency part. This 'filtered' image is then clipped to remove point sources and then Fourier transformed. Subtracting the Fourier components contributing to the stripes in this image from the Fourier transform of the original and transforming back to the image plane yields substantial removal of the stripes.

  1. Imaging sensor for the Geosynchronous Imaging Fourier Transform Spectrometer (GIFTS)

    NASA Astrophysics Data System (ADS)

    Stobie, James A.; Hairston, Allen W.; Tobin, Stephen P.; Huppi, Ronald J.; Huppi, Ray

    2002-12-01

    Accurate high resolution temperature sounding through our atmosphere is paramount to improving our weather forecasting, monitoring, and analysis capability. From the vantagepoint of earth Orbit, remote temperature sounding is becoming a reality and its accuracy is bolstered by recent advances in infrared hyper-spectral sensor capability. One promising approach takes advantage of a two-dimensional, imaging Fourier transform spectrometer to obtain a data cube with the field of view along one plane and multiple IR spectra (one for every FPA pixel) along the orthogonal axis. The spatial resolution is limited only by the pixel pitch in the imaging focal plane and the optics used to collect the data. The maximum optical path difference in the Michelson FTS defines the spectral resolution and dictates the number of path-length interferogram samples (FPA frames required per cube. This paper discusses the unique challenges placed on the focal plane by the Geosynchronous Imaging Fourier Transform Spectrometer (GIFTS) approach and how advanced focal plane technology is applied to satisfy these challenges. Two focal planes are required to provide spectral coverage from 4.4 to 6.1um and 8.85-14.6um. Currently, the GIFT"s LWIR focal plane is the longest wavelength two-dimensional PV HgCdTe array of this size (128 square on 60 um centers) planned for space deployment. The paper presents performance data of Liquid Phase Epitaxy (LPE) fabricated HgCdTe detectors and design details of the advanced readout integrated circuit necessary to meet the demanding requirements of the imaging sensor for the GIFTS instrument.

  2. Optical image encryption based on multifractional Fourier transforms.

    PubMed

    Zhu, B; Liu, S; Ran, Q

    2000-08-15

    We propose a new image encryption algorithm based on a generalized fractional Fourier transform, to which we refer as a multifractional Fourier transform. We encrypt the input image simply by performing the multifractional Fourier transform with two keys. Numerical simulation results are given to verify the algorithm, and an optical implementation setup is also suggested. PMID:18066153

  3. Fourier interpolation stochastic optical fluctuation imaging.

    PubMed

    Stein, Simon C; Huss, Anja; Hähnel, Dirk; Gregor, Ingo; Enderlein, Jörg

    2015-06-15

    Stochastic Optical Fluctuation Imaging (SOFI) is a super-resolution fluorescence microscopy technique which allows to enhance the spatial resolution of an image by evaluating the temporal fluctuations of blinking fluorescent emitters. SOFI is not based on the identification and localization of single molecules such as in the widely used Photoactivation Localization Microsopy (PALM) or Stochastic Optical Reconstruction Microscopy (STORM), but computes a superresolved image via temporal cumulants from a recorded movie. A technical challenge hereby is that, when directly applying the SOFI algorithm to a movie of raw images, the pixel size of the final SOFI image is the same as that of the original images, which becomes problematic when the final SOFI resolution is much smaller than this value. In the past, sophisticated cross-correlation schemes have been used for tackling this problem. Here, we present an alternative, exact, straightforward, and simple solution using an interpolation scheme based on Fourier transforms. We exemplify the method on simulated and experimental data. PMID:26193588

  4. Compact snapshot birefringent imaging Fourier transform spectrometer

    NASA Astrophysics Data System (ADS)

    Kudenov, Michael W.; Dereniak, Eustace L.

    2010-08-01

    The design and implementation of a compact multiple-image Fourier transform spectrometer (FTS) is presented. Based on the multiple-image FTS originally developed by A. Hirai, the presented device offers significant advantages over his original implementation. Namely, its birefringent nature results in a common-path interferometer which makes the spectrometer insensitive to vibration. Furthermore, it enables the potential of making the instrument ultra-compact, thereby improving the portability of the sensor. The theory of the birefringent FTS is provided, followed by details of its specific embodiment. A laboratory proof of concept of the sensor, designed and developed at the Optical Detection Lab, is also presented. Spectral measurements of laboratory sources are provided, including measurements of light-emitting diodes and gas-discharge lamps. These spectra are verified against a calibrated Ocean Optics USB2000 spectrometer. Other data were collected outdoors, demonstrating the sensor's ability to resolve spectral signatures in standard outdoor lighting and environmental conditions.

  5. Fourier transform digital holographic adaptive optics imaging system

    PubMed Central

    Liu, Changgeng; Yu, Xiao; Kim, Myung K.

    2013-01-01

    A Fourier transform digital holographic adaptive optics imaging system and its basic principles are proposed. The CCD is put at the exact Fourier transform plane of the pupil of the eye lens. The spherical curvature introduced by the optics except the eye lens itself is eliminated. The CCD is also at image plane of the target. The point-spread function of the system is directly recorded, making it easier to determine the correct guide-star hologram. Also, the light signal will be stronger at the CCD, especially for phase-aberration sensing. Numerical propagation is avoided. The sensor aperture has nothing to do with the resolution and the possibility of using low coherence or incoherent illumination is opened. The system becomes more efficient and flexible. Although it is intended for ophthalmic use, it also shows potential application in microscopy. The robustness and feasibility of this compact system are demonstrated by simulations and experiments using scattering objects. PMID:23262541

  6. Phase error in Fourier transform spectrometers employing polarization interferometers

    NASA Astrophysics Data System (ADS)

    Wang, Yifan; Kudenov, Michael W.; Craven-Jones, Julia

    2014-05-01

    Phase error is common in reflective interferometers, such as the Michelson. This yields highly asymmetric interferograms that complicate the post-processing of single-sided interference data. Common methods of compensating for phase errors include the Mertz, Forman, and Cannes phase correction techniques. However, birefringent interferometers often have highly symmetric interferograms; thus, compensating for phase errors may represent an unnecessary and/or detrimental step in post processing. In this paper, an analysis of the phase error generated by the Infrared Hyperspectral Imaging Polarimeter (IHIP) is conducted. First, a model of the IHIP is presented that quantifies the phase error in the system. The error associated with calculating spectra from single-sided interferograms, using Mertz phase correction and simple single­sided to double-sided mirroring, is then investigated and compared to "true" double-sided Cannes phase corrected spectra. These error calculations are set within the context of measurements taken from a Michelson interferometer-based Fourier transform spectrometer. Results demonstrate that the phase error of the IHIP is comparatively small and that Mertz phase correction may not be necessary to minimize error in the spectral calculation.

  7. Single beam Fourier transform digital holographic quantitative phase microscopy

    SciTech Connect

    Anand, A. Chhaniwal, V. K.; Mahajan, S.; Trivedi, V.; Faridian, A.; Pedrini, G.; Osten, W.; Dubey, S. K.; Javidi, B.

    2014-03-10

    Quantitative phase contrast microscopy reveals thickness or height information of a biological or technical micro-object under investigation. The information obtained from this process provides a means to study their dynamics. Digital holographic (DH) microscopy is one of the most used, state of the art single-shot quantitative techniques for three dimensional imaging of living cells. Conventional off axis DH microscopy directly provides phase contrast images of the objects. However, this process requires two separate beams and their ratio adjustment for high contrast interference fringes. Also the use of two separate beams may make the system more vulnerable to vibrations. Single beam techniques can overcome these hurdles while remaining compact as well. Here, we describe the development of a single beam DH microscope providing whole field imaging of micro-objects. A hologram of the magnified object projected on to a diffuser co-located with a pinhole is recorded with the use of a commercially available diode laser and an arrayed sensor. A Fourier transform of the recorded hologram directly yields the complex amplitude at the image plane. The method proposed was investigated using various phase objects. It was also used to image the dynamics of human red blood cells in which sub-micrometer level thickness variation were measurable.

  8. Single beam Fourier transform digital holographic quantitative phase microscopy

    NASA Astrophysics Data System (ADS)

    Anand, A.; Faridian, A.; Chhaniwal, V. K.; Mahajan, S.; Trivedi, V.; Dubey, S. K.; Pedrini, G.; Osten, W.; Javidi, B.

    2014-03-01

    Quantitative phase contrast microscopy reveals thickness or height information of a biological or technical micro-object under investigation. The information obtained from this process provides a means to study their dynamics. Digital holographic (DH) microscopy is one of the most used, state of the art single-shot quantitative techniques for three dimensional imaging of living cells. Conventional off axis DH microscopy directly provides phase contrast images of the objects. However, this process requires two separate beams and their ratio adjustment for high contrast interference fringes. Also the use of two separate beams may make the system more vulnerable to vibrations. Single beam techniques can overcome these hurdles while remaining compact as well. Here, we describe the development of a single beam DH microscope providing whole field imaging of micro-objects. A hologram of the magnified object projected on to a diffuser co-located with a pinhole is recorded with the use of a commercially available diode laser and an arrayed sensor. A Fourier transform of the recorded hologram directly yields the complex amplitude at the image plane. The method proposed was investigated using various phase objects. It was also used to image the dynamics of human red blood cells in which sub-micrometer level thickness variation were measurable.

  9. Fourier Coded Aperture Imaging In Nuclear Medicine

    NASA Astrophysics Data System (ADS)

    Chou, Chien

    1984-06-01

    Fourier Aperture (FA) consists of two sinusoidal gratings in contact with each other. One possible mode of operation, both gratings are rotated about the same axis through equal angles in opposite directions. A clear difference moire fringes is shown. The moire frequency depends on the angle between two gratings. This aperture of moire fringes is used as a variable frequency grating. It is able to scan the object spectrum in frequency domain. The summation filtered back projection alqorithm with three different apodizing functions were introduced in the reconstruction. 99mTc gamma ray source and 1" diameter NaI scintillation detector was used in the experiment. The thyroid phantom images show the spatial resolution of FA agree with the theoretical prediction. Three-D images capability is also discussed. The matrix inversion algorithm was used in the computer simulation of 3-D images. The depth resolution of FA is limited by the restricted view angle of the detector. Two plane objects with noise free in different depth were reconstructed.

  10. Phase retrieval using iterative Fourier transform and convex optimization algorithm

    NASA Astrophysics Data System (ADS)

    Zhang, Fen; Cheng, Hong; Zhang, Quanbing; Wei, Sui

    2015-05-01

    Phase is an inherent characteristic of any wave field. Statistics show that greater than 25% of the information is encoded in the amplitude term and 75% of the information is in the phase term. The technique of phase retrieval means acquire phase by computation using magnitude measurements and provides data information for holography display, 3D field reconstruction, X-ray crystallography, diffraction imaging, astronomical imaging and many other applications. Mathematically, solving phase retrieval problem is an inverse problem taking the physical and computation constraints. Some recent algorithms use the principle of compressive sensing, such as PhaseLift, PhaseCut and compressive phase retrieval etc. they formulate phase retrieval problems as one of finding the rank-one solution to a system of linear matrix equations and make the overall algorithm a convex program over n n matrices. However, by "lifting" a vector problem to a matrix one, these methods lead to a much higher computational cost as a result. Furthermore, they only use intensity measurements but few physical constraints. In the paper, a new algorithm is proposed that combines above convex optimization methods with a well known iterative Fourier transform algorithm (IFTA). The IFTA iterates between the object domain and spectral domain to reinforce the physical information and reaches convergence quickly which has been proved in many applications such as compute-generated-hologram (CGH). Herein the output phase of the IFTA is treated as the initial guess of convex optimization methods, and then the reconstructed phase is numerically computed by using modified TFOCS. Simulation results show that the combined algorithm increases the likelihood of successful recovery as well as improves the precision of solution.

  11. Imaging Fourier transform spectrometry of chemical plumes

    NASA Astrophysics Data System (ADS)

    Bradley, Kenneth C.; Gross, Kevin C.; Perram, Glen P.

    2009-05-01

    A midwave infrared (MWIR) imaging Fourier transform spectrometer (FTS), the Telops FIRST-MWE (Field-portable Imaging Radiometric Spectrometer Technology - Midwave Extended) has been utilized for the standoff detection and characterization of chemical plumes. Successful collection and analysis of MWIR hyperspectral imagery of jet engine exhaust has allowed us to produce spatial profiles of both temperature and chemical constituent concentrations of exhaust plumes. Successful characterization of this high temperature combustion event has led to the collection and analysis of hyperspectral imagery of lower temperature emissions from industrial smokestacks. This paper presents MWIR data from remote collection of hyperspectral imagery of methyl salicilate (MeS), a chemical warfare agent simulant, during the Chemical Biological Distributed Early Warning System (CBDEWS) test at Dugway Proving Grounds, UT in 2008. The data did not contain spectral lines associated with emission of MeS. However, a few broad spectral features were present in the background-subtracted plume spectra. Further analysis will be required to assign these features, and determine the utility of MWIR hyperspectral imagery for analysis of chemical warfare agent plumes.

  12. Fourier Analysis and Structure Determination. Part II: Pulse NMR and NMR Imaging.

    ERIC Educational Resources Information Center

    Chesick, John P.

    1989-01-01

    Uses simple pulse NMR experiments to discuss Fourier transforms. Studies the generation of spin echoes used in the imaging procedure. Shows that pulse NMR experiments give signals that are additions of sinusoids of differing amplitudes, frequencies, and phases. (MVL)

  13. Fourier Phase Domain Steganography: Phase Bin Encoding Via Interpolation

    NASA Astrophysics Data System (ADS)

    Rivas, Edward

    2007-04-01

    In recent years there has been an increased interest in audio steganography and watermarking. This is due primarily to two reasons. First, an acute need to improve our national security capabilities in light of terrorist and criminal activity has driven new ideas and experimentation. Secondly, the explosive proliferation of digital media has forced the music industry to rethink how they will protect their intellectual property. Various techniques have been implemented but the phase domain remains a fertile ground for improvement due to the relative robustness to many types of distortion and immunity to the Human Auditory System. A new method for embedding data in the phase domain of the Discrete Fourier Transform of an audio signal is proposed. Focus is given to robustness and low perceptibility, while maintaining a relatively high capacity rate of up to 172 bits/s.

  14. Adaptive chirp-Fourier transform for chirp estimation with applications in ISAR imaging of maneuvering targets

    NASA Astrophysics Data System (ADS)

    Xia, Xiang-Gen; Wang, Genyuan; Chen, Victor C.

    2001-03-01

    This paper first reviews some basic properties of the discrete chirp-Fourier transform and then present an adaptive chirp- Fourier transform, a generalization of the amplitude and phase estimation of sinusoids (APES) algorithm proposed by Li and Stoica for sinusoidal signals. We finally applied it to the ISAR imaging of maneuvering targets.

  15. Speckle size in optical Fourier domain imaging

    NASA Astrophysics Data System (ADS)

    Lamouche, G.; Vergnole, S.; Bisaillon, C.-E.; Dufour, M.; Maciejko, R.; Monchalin, J.-P.

    2007-06-01

    As in conventional time-domain optical coherence tomography (OCT), speckle is inherent to any Optical Fourier Domain Imaging (OFDI) of biological tissue. OFDI is also known as swept-source OCT (SS-OCT). The axial speckle size is mainly determined by the OCT resolution length and the transverse speckle size by the focusing optics illuminating the sample. There is also a contribution from the sample related to the number of scatterers contained within the probed volume. In the OFDI data processing, there is some liberty in selecting the range of wavelengths used and this allows variation in the OCT resolution length. Consequently the probed volume can be varied. By performing measurements on an optical phantom with a controlled density of discrete scatterers and by changing the probed volume with different range of wavelengths in the OFDI data processing, there is an obvious change in the axial speckle size, but we show that there is also a less obvious variation in the transverse speckle size. This work contributes to a better understanding of speckle in OCT.

  16. Color image encryption based on joint fractional Fourier transform correlator

    NASA Astrophysics Data System (ADS)

    Lu, Ding; Jin, Weimin

    2011-06-01

    In this paper, an optical color image encryption/decryption technology based on joint fractional Fourier transform correlator and double random phase encoding (DRPE) is developed. In this method, the joint fractional power spectrum of the image to be encrypted and the key codes is recorded as the encrypted data. Different from the case with classical DRPE, the same key code was used both in the encryption and decryption. The security of the system is enhanced because of the fractional order as a new added key. This method takes full advantage of the parallel processing features of the optical system, and could optically realize single-channel color image encryption. The experimental results indicate that the new method is feasible.

  17. Image reconstruction from pairs of Fourier-transform magnitude

    SciTech Connect

    Hunt, B.R.; Overman, T.L.; Gough, P.

    1998-07-01

    The retrieval of phase information from only the magnitude of the Fourier transform of a signal remains an important problem for many applications. We present an algorithm for phase retrieval when there exist two related sets of Fourier-transform magnitude data. The data are assumed to come from a single object observed in two different polarizations through a distorting medium, so the phase component of the Fourier transform of the object is corrupted. Phase retrieval is accomplished by minimization of a suitable criterion function, which can take three different forms. {copyright} {ital 1998} {ital Optical Society of America}

  18. Imaging Fourier Transform Spectroscopy from a Space Based Platform -- The Herschel/SPIRE Fourier Transform Spectrometer

    NASA Astrophysics Data System (ADS)

    Spencer, Locke Dean

    The Herschel Space Observatory (Herschel), a flagship mission of the European Space Agency (ESA), is comprised of three cryogenically cooled instruments commissioned to explore the far-infrared/submillimetre universe. Herschel's remote orbit at the second Lagrangian point (L2) of the Sun-Earth system, and its cryogenic payload, impose a need for thorough instrument characterization and rigorous testing as there will be no possibility for any servicing after launch. The Spectral and Photometric Imaging Receiver (SPIRE) is one of the instrument payloads aboard Herschel and consists of a three band imaging photometer and a two band imaging spectrometer. The imaging spectrometer on SPIRE consists of a Mach-Zehnder (MZ)-Fourier transform spectrometer (FTS) coupled with bolometric detector arrays to form an imaging FTS (IFTS). This thesis presents experiments conducted to verify the performance of an IFTS system from a space based platform, Le. the use of the SPIRE IFTS within the Herschel space observatory. Prior to launch, the SPIRE instrument has undergone a series of performance verification tests conducted at the Rutherford Appleton Laboratory (RAL) near Oxford, UK. Canada is involved in the SPIRE project through provision of instrument development hardware and software, mission flight software, and support personnel. Through this thesis project I have been stationed at RAL for a period spanning fifteen months to participate in the development, performance verification, and characterization of both the SPIRE FTS and photometer instruments. This thesis discusses Fourier transform spectroscopy and related FTS data processing (Chapter 2). Detailed discussions are included on the spectral phase related to the FTS beamsplitter (Chapter 3), the imaging aspects of the SPIRE IFTS instrument (Chapter 4), and the noise characteristics of the SPIRE bolometer detector arrays as measured using the SPIRE IFTS (Chapter 5). This thesis presents results from experiments performed both on site at the RAL Space Science and Technology Department (SSTD) Assembly Integration Verification (AIV) instrument test facility as well as from the Astronomical Instrumentation Group (AIG) research laboratories within the Department of Physics & Astronomy at the University of Lethbridge.

  19. Operation of a deformable mirror device as a Fourier plane phase modulating filter

    NASA Technical Reports Server (NTRS)

    Florence, James M.; Giles, Michael K.; Smith, Jeffery Z.

    1988-01-01

    The operation of a deformable mirror device (DMD) as a Fourier plane phase modulating filter is described. An analysis of the optical characteristics of the DMD elements as phase modulators is summarized. Analytical and experimental results indicating the existence of a quasi-phase-only operational mode are presented. These results are used to specify the mirror deflection required to implement a binary phase-only image correlation operation. An optical correlator system is implemented using the DMD Fourier plane filter and experimental results from this system are compared with computer simulations of the correlator operation.

  20. Fourier transform infrared (FT-IR) spectroscopy and imaging of the nucleus to characterize DNA contributions in different phases of the cell cycle

    NASA Astrophysics Data System (ADS)

    Tiwari, Saumya; Zong, Xinying; Holton, Sarah E.; Prasanth, K. V.; Bhargava, Rohit

    2015-03-01

    Determination of neoplasia is largely dependent on the state of cell growth. Infrared (IR) spectroscopy has the potential to measure differences between normal and cancerous cells. When analyzing biopsy sections using IR spectroscopy, careful analyses become important since biochemical variations may be misinterpreted due to variations in cell cycle. Processes like DNA replication, transcription and translation to produce proteins are important in determining if the cells are actively dividing but no studies on this aspect using IR spectroscopy have been conducted on isolated cell nuclei. Nuclei hold critical information about the phase of cell and its capacity to divide, but IR spectra of nuclei are often confounded by cytoplasmic signals during data acquisition from intact cells and tissues. Therefore, we sought to separate nuclear signals from cytoplasmic signals and identify spectral differences that characterize different phases of the cell cycle. Both cells and isolated nuclei were analyzed to assess the effect of the cytoplasmic background and to identify spectral changes in nuclei in different phases of cell cycle. We observed that signals of DNA could be obtained when imaging nuclei isolated from cells in different phases of cell cycle, which is in contrast to the oft-cited case in cells wherein nuclear contributions are obscured. The differences across cell cycle phases were more pronounced in nucleic acid regions of the spectra, showing that the use of nuclear spectrum can provide additional information on cellular state. These results can aid in developing computational models that extract nuclear spectra from whole cells and tissues for more accurate assessment of biochemical variations.

  1. Fourier domain OCT imaging of American cockroach nervous system

    NASA Astrophysics Data System (ADS)

    Wyszkowska, Joanna; Gorczynska, Iwona; Ruminski, Daniel; Karnowski, Karol; Kowalczyk, Andrzej; Stankiewicz, Maria; Wojtkowski, Maciej

    2012-01-01

    In this pilot study we demonstrate results of structural Fourier domain OCT imaging of the nervous system of Periplaneta americana L. (American cockroach). The purpose of this research is to develop an OCT apparatus enabling structural imaging of insect neural system. Secondary purpose of the presented research is to develop methods of the sample preparation and handling during the OCT imaging experiments. We have performed imaging in the abdominal nerve cord excised from the American cockroach. For this purpose we have developed a Fourier domain / spectral OCT system operating at 820 nm wavelength range.

  2. Fourier Spectral Filter Array for Optimal Multispectral Imaging.

    PubMed

    Jia, Jie; Barnard, Kenneth J; Hirakawa, Keigo

    2016-04-01

    Limitations to existing multispectral imaging modalities include speed, cost, range, spatial resolution, and application-specific system designs that lack versatility of the hyperspectral imaging modalities. In this paper, we propose a novel general-purpose single-shot passive multispectral imaging modality. Central to this design is a new type of spectral filter array (SFA) based not on the notion of spatially multiplexing narrowband filters, but instead aimed at enabling single-shot Fourier transform spectroscopy. We refer to this new SFA pattern as Fourier SFA, and we prove that this design solves the problem of optimally sampling the hyperspectral image data. PMID:26849867

  3. Fourier-transform ghost imaging with pure far-field correlated thermal light

    SciTech Connect

    Liu Honglin; Shen Xia; Han Shensheng; Zhu Daming

    2007-11-15

    Pure far-field correlated thermal light beams are created with phase grating, and Fourier-transform ghost imaging depending only on the far-field correlation is demonstrated experimentally. Theoretical analysis and the results of experimental investigation of this pure far-field correlated thermal light are presented. Applications which may be exploited with this imaging scheme are discussed.

  4. Invariant quaternion radial harmonic Fourier moments for color image retrieval

    NASA Astrophysics Data System (ADS)

    Xiang-yang, Wang; Wei-yi, Li; Hong-ying, Yang; Pan-pan, Niu; Yong-wei, Li

    2015-03-01

    Moments and moment invariants have become a powerful tool in image processing owing to their image description capability and invariance property. But, conventional methods are mainly introduced to deal with the binary or gray-scale images, and the only approaches for color image always have poor color image description capability. Based on radial harmonic Fourier moments (RHFMs) and quaternion, we introduced the quaternion radial harmonic Fourier moments (QRHFMs) for representing color images in this paper, which can be seen as the generalization of RHFMs for gray-level images. It is shown that the QRHFMs can be obtained from the RHFMs of each color channel. We derived and analyzed the rotation, scaling, and translation (RST) invariant property of QRHFMs. We also discussed the problem of color image retrieval using invariant QRHFMs. Experimental results are provided to illustrate the efficiency of the proposed color image representation.

  5. Geosynchronous Imaging Fourier Transform Spectrometer (GIFTS): Imaging and Tracking Capability

    NASA Technical Reports Server (NTRS)

    Zhou, D. K.; Larar, A. M.; Liu, Xu; Reisse, R. A.; Smith, W. L.; Revercomb, H. E.; Bingham, G. E.; Zollinger, L. J.; Tansock, J. J.; Huppi, Ronald J.

    2007-01-01

    The geosynchronous-imaging Fourier transform spectrometer (GIFTS) engineering demonstration unit (EDU) is an imaging infrared spectrometer designed for atmospheric soundings. It measures the infrared spectrum in two spectral bands (14.6 to 8.8 microns, 6.0 to 4.4 microns) using two 128 128 detector arrays with a spectral resolution of 0.57/cm with a scan duration of approx. 11 seconds. From a geosynchronous orbit, the instrument will have the capability of taking successive measurements of such data to scan desired regions of the globe, from which atmospheric status, cloud parameters, wind field profiles, and other derived products can be retrieved. The GIFTS EDU provides a flexible and accurate testbed for the new challenges of the emerging hyperspectral era. The EDU ground-based measurement experiment, held in Logan, Utah during September 2006, demonstrated its extensive capabilities and potential for geosynchronous and other applications (e.g., Earth observing environmental measurements). This paper addresses the experiment objectives and overall performance of the sensor system with a focus on the GIFTS EDU imaging capability and proof of the GIFTS measurement concept.

  6. Enhancement of Fourier domain optical coherence tomorgraphy images using discrete Fourier transform method

    NASA Astrophysics Data System (ADS)

    Chow, T. H.; Gulam Razul, S.; Ng, B. K.; Ho, Gideon; Yeo, C. B. A.

    2008-02-01

    In this paper, we address the problem of spectral data sampling in Fourier domain optical coherence tomography (FD-OCT). The interferometric information in a Fourier Domain OCT system is retrieved from spectral measurements made using a linear array spectrometer. In such spectrometers, spectral data are available as an array of points equally spaced in the wavelength domain. To obtain the spatial profile, the spectral data have to be converted to the frequency domain before applying the Fourier transform. The inverse relationship between these domains causes an unequal spacing of data points after the spectral data is converted to the frequency domain, resulting in the degradation of the FD-OCT images. The current practice typically utilizes zero-padding and spline interpolation to circumvent this problem. While these algorithms do improve the FD-OCT images, our investigations showed that more can be done to enhance the images. Toward this end, we propose a signal processing algorithm based on non-uniform discrete Fourier transform (NUDFT). The results of our algorithm are compared against the current algorithms on both simulated and experimental results.

  7. Fractional Fourier transform in temporal ghost imaging with classical light

    SciTech Connect

    Setaelae, Tero; Shirai, Tomohiro; Friberg, Ari T.

    2010-10-15

    We investigate temporal, second-order classical ghost imaging with long, incoherent, scalar plane-wave pulses. We prove that in rather general conditions, the intensity correlation function at the output of the setup is given by the fractional Fourier transform of the temporal object. In special cases, the correlation function is shown to reduce to the ordinary Fourier transform and the temporal image of the object. Effects influencing the visibility and the resolution are considered. This work extends certain known results on spatial ghost imaging into the time domain and could find applications in temporal tomography of pulses.

  8. Theoretical study of Fourier-transform acousto-optic imaging.

    PubMed

    Barjean, Kinia; Ramaz, François; Tualle, Jean-Michel

    2016-05-01

    We propose a full theoretical study of Fourier-transform acousto-optic imaging, which we recently introduced and experimentally assessed in [Opt. Lett.40, 705-708 (2015)OPLEDP0146-959210.1364/OL.40.000705] as an alternative to achieve axial resolution in acousto-optic imaging with a higher signal-to-noise ratio. PMID:27140883

  9. Electro-Optical Imaging Fourier-Transform Spectrometer

    NASA Technical Reports Server (NTRS)

    Chao, Tien-Hsin; Zhou, Hanying

    2006-01-01

    An electro-optical (E-O) imaging Fourier-transform spectrometer (IFTS), now under development, is a prototype of improved imaging spectrometers to be used for hyperspectral imaging, especially in the infrared spectral region. Unlike both imaging and non-imaging traditional Fourier-transform spectrometers, the E-O IFTS does not contain any moving parts. Elimination of the moving parts and the associated actuator mechanisms and supporting structures would increase reliability while enabling reductions in size and mass, relative to traditional Fourier-transform spectrometers that offer equivalent capabilities. Elimination of moving parts would also eliminate the vibrations caused by the motions of those parts. Figure 1 schematically depicts a traditional Fourier-transform spectrometer, wherein a critical time delay is varied by translating one the mirrors of a Michelson interferometer. The time-dependent optical output is a periodic representation of the input spectrum. Data characterizing the input spectrum are generated through fast-Fourier-transform (FFT) post-processing of the output in conjunction with the varying time delay.

  10. Asymmetric multiple-image encryption based on the cascaded fractional Fourier transform

    NASA Astrophysics Data System (ADS)

    Li, Yanbin; Zhang, Feng; Li, Yuanchao; Tao, Ran

    2015-09-01

    A multiple-image cryptosystem is proposed based on the cascaded fractional Fourier transform. During an encryption procedure, each of the original images is directly separated into two phase masks. A portion of the masks is subsequently modulated into an interim mask, which is encrypted into the ciphertext image; the others are used as the encryption keys. Using phase truncation in the fractional Fourier domain, one can use an asymmetric cryptosystem to produce a real-valued noise-like ciphertext, while a legal user can reconstruct all of the original images using a different group of phase masks. The encryption key is an indivisible part of the corresponding original image and is still useful during decryption. The proposed system has high resistance to various potential attacks, including the chosen-plaintext attack. Numerical simulations also demonstrate the security and feasibility of the proposed scheme.

  11. Full-range Fourier domain polarization-sensitive optical coherence tomography using sinusoidal phase modulation

    NASA Astrophysics Data System (ADS)

    Chen, Yan; Wang, Xiangzhao; Li, Zhongliang; Nan, Nan; Guo, Xin

    2014-09-01

    We present a full-range Fourier domain polarization-sensitive optical coherence tomography technique which is able to obtain images of retardance, fast optical axis and intensity of sample. In this technique, the sinusoidal phase modulation is introduced into the spectral interferograms while the probe beam scans over the sample (B-scan). Then the complex horizontal and vertical signals are reconstructed by demodulation. By the Fourier transformation of the two interferograms, the full range images are obtained. Herein, the typical linear phase modulation is modified to sinusoidal phase modulation, which improves the system tolerance of sample movements and avoids sensitivity fall-off along the transverse scan. Furthermore, the images are obtained through the recombination of the horizontal and vertical polarization beam components acquired by a single camera, which avoids the problems of synchronous control and alignments in the situation of two cameras.

  12. Medical Image Provessing using Transient Fourier Holography in Bacteriorhodopsin Films

    NASA Astrophysics Data System (ADS)

    Kothapalli, Sri-Rajasekhar; Wu, Pengfei; Yelleswarapu, Chandra; Devulapalli, Rao

    2005-03-01

    A real-time optical Fourier image processing system is demonstrated for early detection of microcalcifications in screen film as well as digital mammograms. The principle is based on recording and reconstructing the transient photoisomerizative grating formed in the bR film. At first Fourier hologram is recorded by spatially overlapping the Fourier transformed object beam with the reference beam in the bR film. Then the object beam is blocked and the reference beam performs the reconstruction of the recorded Fourier hologram. The optimum of diffraction efficiency occurs when object beam intensity is matched to the reference beam intensity. We exploit this technique to process mammograms in real-time for identification of microcalcifications buried in the soft tissue for early detection of breast cancer. A novel feature of the technique is the ability to transient display of selected spatial frequencies in the reconstructing process which enables the radiologists to study the features of interest in time scale.

  13. Comparative analysis of imaging configurations and objectives for Fourier microscopy.

    PubMed

    Kurvits, Jonathan A; Jiang, Mingming; Zia, Rashid

    2015-11-01

    Fourier microscopy is becoming an increasingly important tool for the analysis of optical nanostructures and quantum emitters. However, achieving quantitative Fourier space measurements requires a thorough understanding of the impact of aberrations introduced by optical microscopes that have been optimized for conventional real-space imaging. Here we present a detailed framework for analyzing the performance of microscope objectives for several common Fourier imaging configurations. To this end, we model objectives from Nikon, Olympus, and Zeiss using parameters that were inferred from patent literature and confirmed, where possible, by physical disassembly. We then examine the aberrations most relevant to Fourier microscopy, including the alignment tolerances of apodization factors for different objective classes, the effect of magnification on the modulation transfer function, and vignetting-induced reductions of the effective numerical aperture for wide-field measurements. Based on this analysis, we identify an optimal objective class and imaging configuration for Fourier microscopy. In addition, the Zemax files for the objectives and setups used in this analysis have been made publicly available as a resource for future studies. PMID:26560923

  14. Fourier Image Sharpness Sensor for Laser Communications - Oral Paper

    NASA Astrophysics Data System (ADS)

    Walker, Kristin N.; Tyson, Robert K.

    2008-01-01

    Conventional adaptive optics systems use direct wavefront sensing, such as the Shack-Hartmann sensor, requiring the measurement and reconstruction of the incoming wavefront at the pupil plane. Indirect wavefront sensing, such as image sharpening, is based upon information in the image itself. Image sharpening with adaptive optics can be applied where the object is known, as in a laser communication link. We are developing an image sharpness sensor based on the information found in the Fourier spectrum of the image. High spatial frequencies contain information about the edges and fine detail of the image. Our premise is that maximizing the high spatial frequencies will sharpen the image. In our method the Fourier transform of the image is generated optically (and essentially instantaneously) and then the low spatial frequencies are filtered out with an opaque mask. The remaining high spatial frequencies of the Fourier spectrum are integrated optically and a sharpness signal is measured with a single photodetector. The collected sharpness value is used in a closed-loop to control the deformable mirror until the sharpness is maximized. We have constructed a simulation to study the sensor and its performance in an adaptive optics system. We will discuss the sensitivity of this method based on the results of our investigation and mention some of the limitations of the system.

  15. Phase in Optical Image Processing

    NASA Astrophysics Data System (ADS)

    Naughton, Thomas J.

    2010-04-01

    The use of phase has a long standing history in optical image processing, with early milestones being in the field of pattern recognition, such as VanderLugt's practical construction technique for matched filters, and (implicitly) Goodman's joint Fourier transform correlator. In recent years, the flexibility afforded by phase-only spatial light modulators and digital holography, for example, has enabled many processing techniques based on the explicit encoding and decoding of phase. One application area concerns efficient numerical computations. Pushing phase measurement to its physical limits, designs employing the physical properties of phase have ranged from the sensible to the wonderful, in some cases making computationally easy problems easier to solve and in other cases addressing mathematics' most challenging computationally hard problems. Another application area is optical image encryption, in which, typically, a phase mask modulates the fractional Fourier transformed coefficients of a perturbed input image, and the phase of the inverse transform is then sensed as the encrypted image. The inherent linearity that makes the system so elegant mitigates against its use as an effective encryption technique, but we show how a combination of optical and digital techniques can restore confidence in that security. We conclude with the concept of digital hologram image processing, and applications of same that are uniquely suited to optical implementation, where the processing, recognition, or encryption step operates on full field information, such as that emanating from a coherently illuminated real-world three-dimensional object.

  16. Fourier-ring descriptor to characterize rare circulating cells from images generated using immunofluorescence microscopy.

    PubMed

    Emerson, Tegan; Kirby, Michael; Bethel, Kelly; Kolatkar, Anand; Luttgen, Madelyn; O'Hara, Stephen; Newton, Paul; Kuhn, Peter

    2015-03-01

    We address the problem of subclassification of rare circulating cells using data driven feature selection from images of candidate circulating tumor cells from patients diagnosed with breast, prostate, or lung cancer. We determine a set of low level features which can differentiate among candidate cell types. We have implemented an image representation based on concentric Fourier rings (FRDs) which allow us to exploit size variations and morphological differences among cells while being rotationally invariant. We discuss potential clinical use in the context of treatment monitoring for cancer patients with metastatic disease. PMID:25456146

  17. Fourier Power Spectrum Characteristics of Face Photographs: Attractiveness Perception Depends on Low-Level Image Properties

    PubMed Central

    Langner, Oliver; Wiese, Holger; Redies, Christoph

    2015-01-01

    We investigated whether low-level processed image properties that are shared by natural scenes and artworks – but not veridical face photographs – affect the perception of facial attractiveness and age. Specifically, we considered the slope of the radially averaged Fourier power spectrum in a log-log plot. This slope is a measure of the distribution of special frequency power in an image. Images of natural scenes and artworks possess – compared to face images – a relatively shallow slope (i.e., increased high spatial frequency power). Since aesthetic perception might be based on the efficient processing of images with natural scene statistics, we assumed that the perception of facial attractiveness might also be affected by these properties. We calculated Fourier slope and other beauty-associated measurements in face images and correlated them with ratings of attractiveness and age of the depicted persons (Study 1). We found that Fourier slope – in contrast to the other tested image properties – did not predict attractiveness ratings when we controlled for age. In Study 2A, we overlaid face images with random-phase patterns with different statistics. Patterns with a slope similar to those in natural scenes and artworks resulted in lower attractiveness and higher age ratings. In Studies 2B and 2C, we directly manipulated the Fourier slope of face images and found that images with shallower slopes were rated as more attractive. Additionally, attractiveness of unaltered faces was affected by the Fourier slope of a random-phase background (Study 3). Faces in front of backgrounds with statistics similar to natural scenes and faces were rated as more attractive. We conclude that facial attractiveness ratings are affected by specific image properties. An explanation might be the efficient coding hypothesis. PMID:25835539

  18. Fourier power spectrum characteristics of face photographs: attractiveness perception depends on low-level image properties.

    PubMed

    Menzel, Claudia; Hayn-Leichsenring, Gregor U; Langner, Oliver; Wiese, Holger; Redies, Christoph

    2015-01-01

    We investigated whether low-level processed image properties that are shared by natural scenes and artworks - but not veridical face photographs - affect the perception of facial attractiveness and age. Specifically, we considered the slope of the radially averaged Fourier power spectrum in a log-log plot. This slope is a measure of the distribution of special frequency power in an image. Images of natural scenes and artworks possess - compared to face images - a relatively shallow slope (i.e., increased high spatial frequency power). Since aesthetic perception might be based on the efficient processing of images with natural scene statistics, we assumed that the perception of facial attractiveness might also be affected by these properties. We calculated Fourier slope and other beauty-associated measurements in face images and correlated them with ratings of attractiveness and age of the depicted persons (Study 1). We found that Fourier slope - in contrast to the other tested image properties - did not predict attractiveness ratings when we controlled for age. In Study 2A, we overlaid face images with random-phase patterns with different statistics. Patterns with a slope similar to those in natural scenes and artworks resulted in lower attractiveness and higher age ratings. In Studies 2B and 2C, we directly manipulated the Fourier slope of face images and found that images with shallower slopes were rated as more attractive. Additionally, attractiveness of unaltered faces was affected by the Fourier slope of a random-phase background (Study 3). Faces in front of backgrounds with statistics similar to natural scenes and faces were rated as more attractive. We conclude that facial attractiveness ratings are affected by specific image properties. An explanation might be the efficient coding hypothesis. PMID:25835539

  19. Pansharpening of multispectral images using filtering in Fourier domain

    NASA Astrophysics Data System (ADS)

    Akoguz, Alper; Kurt, Burak; Pinar, Sedef K.

    2014-10-01

    In this study, there is examined filtering based pansharpening methods which means of using several 2D FIR filters in Fourier domain which implies that the filters are applied after taking 2D Discrete Fourier Transform of both multispectral and panchromatic image and after the pansharpening process in Fourier domain, the resulting pansharpened image is obtained with an inverse 2D DFT. In addition, these methods are compared with commonly used fusion methods which are combined as modulation based and component substitution based methods. The algorithms are applied to SPOT 6 co-registered image couples that were acquired simultaneously. Couples are chosen for three different regions which are a city image (Gebze/Turkey), a forest image (Istanbul/Turkey) and an agriculture field image (Sanliurfa/Turkey) in order to analyse the methods in different regional characteristics. These methods are compared by the fusion quality assessments that have common acceptance in community. The results of these quality assessments shows the filtering based methods had the best scores among the traditional methods.

  20. Quantification of fibre polymerization through Fourier space image analysis.

    PubMed

    Nekouzadeh, Ali; Genin, Guy M

    2011-08-01

    Quantification of changes in the total length of randomly oriented and possibly curved lines appearing in an image is a necessity in a wide variety of biological applications. Here, we present an automated approach based upon Fourier space analysis. Scaled, band-pass filtered power spectral densities of greyscale images are integrated to provide a quantitative measurement of the total length of lines of a particular range of thicknesses appearing in an image. A procedure is presented to correct for changes in image intensity. The method is most accurate for two-dimensional processes with fibres that do not occlude one another. PMID:24959096

  1. Image encryption based on the multiple-parameter discrete fractional Fourier transform and chaos function

    NASA Astrophysics Data System (ADS)

    Lang, Jun; Tao, Ran; Wang, Yue

    2010-05-01

    In recent years, the chaos-based cryptographic algorithms have suggested some new and efficient ways to develop secure image encryption techniques. In this paper, we propose a new approach for image encryption based on the multiple-parameter discrete fractional Fourier transform and chaotic logistic maps in order to meet the requirements of the secure image transmission. In the proposed image encryption scheme, the image is encrypted by juxtaposition of sections of the image in the multiple-parameter discrete fractional Fourier domains and the alignment of sections is determined by chaotic logistic maps. This method does not require the use of phase keys. The new method has been compared with several existing methods and shows comparable or superior robustness to blind decryption.

  2. Affine cryptosystem of double-random-phase encryption based on the fractional Fourier transform

    NASA Astrophysics Data System (ADS)

    Xin, Zhou; Sheng, Yuan; Sheng-Wei, Wang; Jian, Xie

    2006-11-01

    An affine mapping mathematical expression of the double-random-phase encryption technique has been deduced utilizing the matrix form of discrete fractional Fourier transforms. This expression clearly describes the encryption laws of the double-random-phase encoding techniques based on both the fractional Fourier transform and the ordinary Fourier transform. The encryption process may be regarded as a substantial optical realization of the affine cryptosystem. It has been illustrated that the encryption process converts the original image into a white Gaussian noise with a zero-mean value. Also, the decryption process converts the data deviations of the encrypted image into white Gaussian noises, regardless of the type of data deviations. These noises superimpose on the decrypted image and degrade the signal-to-noise ratio. Numerical simulations have been implemented for the different types of noises introduced into the encrypted image, such as the white noise with uniform distribution probability, the white noise with Gaussian distribution probability, colored noise, and the partial occlusion of the encrypted image.

  3. Binary-Phase Fourier Gratings for Nonuniform Array Generation

    NASA Technical Reports Server (NTRS)

    Keys, Andrew S.; Crow, Robert W.; Ashley, Paul R.

    2003-01-01

    We describe a design method for a binary-phase Fourier grating that generates an array of spots with nonuniform, user-defined intensities symmetric about the zeroth order. Like the Dammann fanout grating approach, the binary-phase Fourier grating uses only two phase levels in its grating surface profile to generate the final spot array. Unlike the Dammann fanout grating approach, this method allows for the generation of nonuniform, user-defined intensities within the final fanout pattern. Restrictions governing the specification and realization of the array's individual spot intensities are discussed. Design methods used to realize the grating employ both simulated annealing and nonlinear optimization approaches to locate optimal solutions to the grating design problem. The end-use application driving this development operates in the near- to mid-infrared spectrum - allowing for higher resolution in grating specification and fabrication with respect to wavelength than may be available in visible spectrum applications. Fabrication of a grating generating a user-defined nine spot pattern is accomplished in GaAs for the near-infrared. Characterization of the grating is provided through the measurement of individual spot intensities, array uniformity, and overall efficiency. Final measurements are compared to calculated values with a discussion of the results.

  4. 360-degrees profilometry using strip-light projection coupled to Fourier phase-demodulation.

    PubMed

    Servin, Manuel; Padilla, Moises; Garnica, Guillermo

    2016-01-11

    360 degrees (360°) digitalization of three dimensional (3D) solids using a projected light-strip is a well-established technique in academic and commercial profilometers. These profilometers project a light-strip over the digitizing solid while the solid is rotated a full revolution or 360-degrees. Then, a computer program typically extracts the centroid of this light-strip, and by triangulation one obtains the shape of the solid. Here instead of using intensity-based light-strip centroid estimation, we propose to use Fourier phase-demodulation for 360° solid digitalization. The advantage of Fourier demodulation over strip-centroid estimation is that the accuracy of phase-demodulation linearly-increases with the fringe density, while in strip-light the centroid-estimation errors are independent. Here we proposed first to construct a carrier-frequency fringe-pattern by closely adding the individual light-strip images recorded while the solid is being rotated. Next, this high-density fringe-pattern is phase-demodulated using the standard Fourier technique. To test the feasibility of this Fourier demodulation approach, we have digitized two solids with increasing topographic complexity: a Rubik's cube and a plastic model of a human-skull. According to our results, phase demodulation based on the Fourier technique is less noisy than triangulation based on centroid light-strip estimation. Moreover, Fourier demodulation also provides the amplitude of the analytic signal which is a valuable information for the visualization of surface details. PMID:26832248

  5. Phase object power mapping and cosmetic defects enhancement by Fourier-based deflectometry

    NASA Astrophysics Data System (ADS)

    Beghuin, D.; Dubois, X.; Joannes, L.

    2009-06-01

    Optical deflectometry, likewise many other optical methods, permits to reconstruct the wavefront deformations induced by a refractive or a phase object. In this paper, a Fourier based deflectometry method is presented. A telecentric imaging system acquires pictures of a grating being the superposition of two crossed Ronchi rulings of the same spatial frequency. The object under test is inserted in the optical path between the grating and the telecentric imaging system. The presented Fourier based image analysis permits to extract the wavefront derivatives, and therefore permits to reconstruct the wavefront or the local power of the object. In this paper, the method is illustrated on several free form thermoplasic elements, the sensitivity is determined experimentally, the precision is analyzed and the ability to characterize cosmetic defects is evaluated.

  6. Gradient-based image recovery methods from incomplete Fourier measurements.

    PubMed

    Patel, Vishal M; Maleh, Ray; Gilbert, Anna C; Chellappa, Rama

    2012-01-01

    A major problem in imaging applications such as magnetic resonance imaging and synthetic aperture radar is the task of trying to reconstruct an image with the smallest possible set of Fourier samples, every single one of which has a potential time and/or power cost. The theory of compressive sensing (CS) points to ways of exploiting inherent sparsity in such images in order to achieve accurate recovery using sub-Nyquist sampling schemes. Traditional CS approaches to this problem consist of solving total-variation (TV) minimization programs with Fourier measurement constraints or other variations thereof. This paper takes a different approach. Since the horizontal and vertical differences of a medical image are each more sparse or compressible than the corresponding TV image, CS methods will be more successful in recovering these differences individually. We develop an algorithm called GradientRec that uses a CS algorithm to recover the horizontal and vertical gradients and then estimates the original image from these gradients. We present two methods of solving the latter inverse problem, i.e., one based on least-square optimization and the other based on a generalized Poisson solver. After a thorough derivation of our complete algorithm, we present the results of various experiments that compare the effectiveness of the proposed method against other leading methods. PMID:21690011

  7. Optimal color image restoration: Wiener filter and quaternion Fourier transform

    NASA Astrophysics Data System (ADS)

    Grigoryan, Artyom M.; Agaian, Sos S.

    2015-03-01

    In this paper, we consider the model of quaternion signal degradation when the signal is convoluted and an additive noise is added. The classical model of such a model leads to the solution of the optimal Wiener filter, where the optimality with respect to the mean square error. The characteristic of this filter can be found in the frequency domain by using the Fourier transform. For quaternion signals, the inverse problem is complicated by the fact that the quaternion arithmetic is not commutative. The quaternion Fourier transform does not map the convolution to the operation of multiplication. In this paper, we analyze the linear model of the signal and image degradation with an additive independent noise and the optimal filtration of the signal and images in the frequency domain and in the quaternion space.

  8. Quantum Noise of Fourier-Coded Aperture Imaging System

    NASA Astrophysics Data System (ADS)

    Chou, Chien; King, Hong-Jueng

    1994-04-01

    The single-grating aperture (SGA) and Fourier aperture (FA) both behave as variable frequency gratings to record the object spectrum directly in a Fourier domain when quantum noise is originally generated in this region. This is in contrast to a stationary coded aperture in which the noise appears in the space domain in the shadow-casting images. The noise properties of SGA and FA imaging systems, using the summation filtered backprojection reconstruction algorithm, have been determined. They are proportional to the square root of the intensity distribution of the object. From the theoretical calculations, signal-to-noise ratios of SGA and FA show the same performance as the SNR of a pinhole camera for small objects. However, for larger objects, SGA and FA show better performance than the pinhole camera. The calculated SNRs of a point and a disc object agree with the experimental results.

  9. A phase space model of Fourier ptychographic microscopy

    PubMed Central

    Horstmeyer, Roarke; Yang, Changhuei

    2014-01-01

    A new computational imaging technique, termed Fourier ptychographic microscopy (FPM), uses a sequence of low-resolution images captured under varied illumination to iteratively converge upon a high-resolution complex sample estimate. Here, we propose a mathematical model of FPM that explicitly connects its operation to conventional ptychography, a common procedure applied to electron and X-ray diffractive imaging. Our mathematical framework demonstrates that under ideal illumination conditions, conventional ptychography and FPM both produce datasets that are mathematically linked by a linear transformation. We hope this finding encourages the future cross-pollination of ideas between two otherwise unconnected experimental imaging procedures. In addition, the coherence state of the illumination source used by each imaging platform is critical to successful operation, yet currently not well understood. We apply our mathematical framework to demonstrate that partial coherence uniquely alters both conventional ptychography’s and FPM’s captured data, but up to a certain threshold can still lead to accurate resolution-enhanced imaging through appropriate computational post-processing. We verify this theoretical finding through simulation and experiment. PMID:24514995

  10. High-resolution lensless Fourier transform holography for microstructure imaging

    NASA Astrophysics Data System (ADS)

    Zhao, Jie; Wang, Dayong; Wang, Huaying; Xie, Jianjun

    2007-12-01

    Digital holography combines the advantages of the optical holography and the computers. It can implement an all-digital processing and has the quasi real-time property. With lensless Fourier transform recording architecture, the limited bandwidth of CCD camera can be utilized sufficiently, and the sampling theorem is satisfied easily. Therefore, high-resolution can be achieved. So it is preferred in the microstructure imaging. In the paper, based on the Fresnel diffraction theory and the off-axis lensless Fourier transform recording architecture, the experimental optimization and correspondingly the digital reconstruction was investigated. Also, the lateral resolution of the reconstructed image was analyzed and improved by the proposed techniques. When the USAF test target was imaged without any pre-magnification, the lateral resolution of 3.1μm was achieved, which matched the theoretical prediction very well. The key points to achieve high resolution image are to use the smaller object and to arrange the distance between the object and the CCD plane as short as possible. Meanwhile, properly overlapping the reconstructed image with the DC term was helpful to improve the resolution. The noise in the reconstructed image could be reduced greatly by choosing the optical elements precisely and adjusting the beam path finely. The experimental results demonstrated that it is possible for the digital holographic microscopy to produce the high resolution image without the objective pre-magnification. The results also showed that, with a high quality hologram, the special image processing during the reconstruction may be unnecessary to obtain a high quality image.

  11. The use of Fourier reverse transforms in crystallographic phase refinement

    SciTech Connect

    Ringrose, S.

    1997-10-08

    Often a crystallographer obtains an electron density map which shows only part of the structure. In such cases, the phasing of the trial model is poor enough that the electron density map may show peaks in some of the atomic positions, but other atomic positions are not visible. There may also be extraneous peaks present which are not due to atomic positions. A method for determination of crystal structures that have resisted solution through normal crystallographic methods has been developed. PHASER is a series of FORTRAN programs which aids in the structure solution of poorly phased electron density maps by refining the crystallographic phases. It facilitates the refinement of such poorly phased electron density maps for difficult structures which might otherwise not be solvable. The trial model, which serves as the starting point for the phase refinement, may be acquired by several routes such as direct methods or Patterson methods. Modifications are made to the reverse transform process based on several assumptions. First, the starting electron density map is modified based on the fact that physically the electron density map must be non-negative at all points. In practice a small positive cutoff is used. A reverse Fourier transform is computed based on the modified electron density map. Secondly, the authors assume that a better electron density map will result by using the observed magnitudes of the structure factors combined with the phases calculated in the reverse transform. After convergence has been reached, more atomic positions and less extraneous peaks are observed in the refined electron density map. The starting model need not be very large to achieve success with PHASER; successful phase refinement has been achieved with a starting model that consists of only 5% of the total scattering power of the full molecule. The second part of the thesis discusses three crystal structure determinations.

  12. Imaging Fourier transform spectrometer (IFTS): parametric sensitivity analysis

    NASA Astrophysics Data System (ADS)

    Keller, Robert A.; Lomheim, Terrence S.

    2005-06-01

    Imaging Fourier transform spectrometers (IFTS) allow for very high spectral resolution hyperspectral imaging while using moderate size 2D focal plane arrays in a staring mode. This is not the case for slit scanning dispersive imaging spectrometers where spectral sampling is related to the focal plane pixel count along the spectral dimension of the 2D focal plane used in such an instrument. This can become a major issue in the longwave infrared (LWIR) where the operability and yield of highly sensitivity arrays (i.e.HgCdTe) of large dimension are generally poor. However using an IFTS introduces its own unique set of issues and tradeoffs. In this paper we develop simplified equations for describing the sensitivity of an IFTS, including the effects of data windowing. These equations provide useful insights into the optical, focal plane and operational design trade space that must be considered when examining IFTS concepts aimed at a specific sensitivity and spectral resolution application. The approach is illustrated by computing the LWIR noise-equivalent spectral radiance (NESR) corresponding to the NASA Geosynchronous Imaging Fourier Transform Spectrometer (GIFTS) concept assuming a proven and reasonable noise-equivalent irradiance (NEI) capability for the focal plane.

  13. Imaging the sun in hard x rays using Fourier telescopes

    NASA Technical Reports Server (NTRS)

    Campbell, J. W.

    1993-01-01

    For several years, solar flares have been observed with a variety of instruments confirming that tremendous amounts of energy are locally stored in the solar magnetic field and then rapidly released during the life of the flare. In concert with observations, theorists have attempted to describe the means by which these energetic events occur and evolve. Two competing theories have emerged and have stood the test of time. One theory describes the flare in terms of nonthermal, electron beam injection into a thick target while the other uses a thermal approach. Both theories provide results which are reasonably consistent with current observations; but to date, none have been able to provide conclusive evidence as to the validity of either model. Imaging on short time scales (1 s) and/or small size scales (1 arc s) should give definitive answers to these questions. In order to test whether a realistic telescope can indeed discriminate between models, we construct model sources based upon the thermal and the nonthermal models and calculate the emission as a function of time and energy in the range from 10 to 100 keV. In addition, we construct model telescopes representing both the spatial modulation collimator (SMC) and the rotating modulation collimator (RMC) techniques of observation using random photon counting statistics. With these two types of telescopes we numerically simulate the instrument response to the above two model flares to see if there are distinct x-ray signatures which may be discernable. We find that theoretical descriptions of the primary models of solar flares do indeed predict different hard x-ray signatures for 1 sec time scales and at 1-5 arc sec spatial resolution. However, these distinguishing signatures can best be observed early in the impulsive phase and from a position perpendicular to the plane of the loop. Furthermore, we find that Fourier telescopes with reasonable and currently attainable design characteristics can image these signatures and that the same sensitive areas and short temporal integration times relative to source evolution (i.e., 1 s), the RMC and the SMC will both provide about the same performance.

  14. Asymmetric multiple-image encryption based on coupled logistic maps in fractional Fourier transform domain

    NASA Astrophysics Data System (ADS)

    Sui, Liansheng; Duan, Kuaikuai; Liang, Junli; Zhang, Zhiqiang; Meng, Haining

    2014-11-01

    A multiple-image encryption scheme is proposed based on the asymmetric technique, in which the encryption keys are not identical to the decryption ones. First, each plain image is scrambled based on a sequence of chaotic pairs generated with a system of two symmetrically coupled identical logistic maps. Then, the phase-only function of each scrambled image is retrieved with an iterative phase retrieval process in the fractional Fourier transform domain. Second, all phase-only functions are modulated into an interim, which is encrypted into the ciphertext with stationary white noise distribution by using the fractional Fourier transform and chaotic diffusion. In the encryption process, three random phase functions are used as encryption keys to retrieve the phase-only functions of plain images. Simultaneously, three decryption keys are generated in the encryption process, which make the proposed encryption scheme has high security against various attacks, such as chosen plaintext attack. The peak signal-to-noise is used to evaluate the quality of the decrypted image, which shows that the encryption capacity of the proposed scheme is enhanced considerably. Numerical simulations demonstrate the validity and efficiency of the proposed method.

  15. Imaging Organ of Corti Vibration Using Fourier-Domain OCT

    NASA Astrophysics Data System (ADS)

    Choudhury, Niloy; Chen, Fangyi; Fridberger, Anders; Zha, Dingjun; Jacques, Steven L.; Wang, Ruikang K.; Nuttall, Alfred L.

    2011-11-01

    Measuring the sound stimulated vibration from various structures in the organ of Corti is important in understanding how the small vibrations are amplified and detected. In this study we examine the feasibility of using phase-sensitive Fourier domain optical coherence tomography (PSFD-OCT) to measure vibration of the cellular structures of the organ of Corti. PSFD-OCT is a low coherence interferrometry system where the interferrogram is detected as a function of wavelength. The phase of the Fourier transformation of the detected spectra contains path deference (between the sample arm and the reference arm) information of the interferometer. In PSFD-OCT this phase is measured as a function of time and thus any time dependent change in the path difference between the sample arm and the reference arm can be detected. In the experiment, we used an in vitro preparation of the guinea pig cochlea and made a surgical opening at the apical end to access the organ of Corti. By applying tones with different frequencies via the intact middle ear, we recorded the structural vibration inside the organ of Corti. Vibration amplitude and phase of different substructures were mapped on a cross-section view of the organ of Corti. Although the measurements were made at the apical turn of the cochlea, it will be possible to make vibration measurement from various turns of the cochlea. The noise floor of the system was 0.3 nm, calibrated using a piezo stack as a calibrator.

  16. Geometric phase analysis based on the windowed Fourier transform for the deformation field measurement

    NASA Astrophysics Data System (ADS)

    Dai, Xianglu; Xie, Huimin; Wang, Qinghua

    2014-06-01

    The geometric phase analysis (GPA), an important image-based deformation measurement method, has been used at both micro- and nano-scale. However, when a deformed image has apparent distortion, non-ignorable error in the obtained deformation field could occur by using this method. In this paper, the geometric phase analysis based on the windowed Fourier transform (WFT) is proposed to solve the above-mentioned issue, defined as the WFT-GPA method. In WFT-GPA, instead of the Fourier transform (FT), the WFT is utilized to extract the phase field block by block, and therefore more accurate local phase information can be acquired. The simulation tests, which include detailed discussion of influence factors for measurement accuracy such as window size and image noise, are conducted with digital deformed grids. The results verify that the WFT-GPA method not only keeps all advantages of traditional GPA method, but also owns a better accuracy for deformation measurement. Finally, the WFT-GPA method is applied to measure the machining distortion incurred in soft ultraviolet nanoimprint lithography (UV-NIL) process. The successful measurement shows the feasibility of this method and offers a full-field way for characterizing the replication quality of UV-NIL process.

  17. Instrument concept of the imaging Fourier transform spectrometer GLORIA

    NASA Astrophysics Data System (ADS)

    Friedl-Vallon, F.; Gulde, T.; Hase, F.; Kleinert, A.; Kulessa, T.; Maucher, G.; Neubert, T.; Olschewski, F.; Piesch, C.; Preusse, P.; Rongen, H.; Sartorius, C.; Schneider, H.; Schönfeld, A.; Tan, V.; Bayer, N.; Blank, J.; Dapp, R.; Ebersoldt, A.; Fischer, H.; Graf, F.; Guggenmoser, T.; Höpfner, M.; Kaufmann, M.; Kretschmer, E.; Latzko, T.; Nordmeyer, H.; Oelhaf, H.; Orphal, J.; Riese, M.; Schardt, G.; Schillings, J.; Sha, M. K.; Suminska-Ebersoldt, O.; Ungermann, J.

    2014-03-01

    The Gimballed Limb Observer for Radiance Imaging of the Atmosphere (GLORIA) is an imaging limb emission sounder operating in the thermal infrared region. It is designed to provide measurements of the Upper Troposphere/Lower Stratosphere with high spatial and high spectral resolution. The instrument consists of an imaging Fourier transform spectrometer integrated in a gimbal. The assembly can be mounted in the belly pod of the German high altitude and long range research aircraft HALO and in instrument bays of the Russian M55 Geophysica. Measurements are made predominantly in two distinct modes: the chemistry mode emphasises chemical analysis with high spectral resolution, the dynamics mode focuses on dynamical processes of the atmosphere with very high spatial resolution. In addition the instrument allows tomographic analyses of air volumes. The first measurement campaigns have shown compliance with key performance and operational requirements.

  18. Instrument concept of the imaging Fourier transform spectrometer GLORIA

    NASA Astrophysics Data System (ADS)

    Friedl-Vallon, F.; Gulde, T.; Hase, F.; Kleinert, A.; Kulessa, T.; Maucher, G.; Neubert, T.; Olschewski, F.; Piesch, C.; Preusse, P.; Rongen, H.; Sartorius, C.; Schneider, H.; Schönfeld, A.; Tan, V.; Bayer, N.; Blank, J.; Dapp, R.; Ebersoldt, A.; Fischer, H.; Graf, F.; Guggenmoser, T.; Höpfner, M.; Kaufmann, M.; Kretschmer, E.; Latzko, T.; Nordmeyer, H.; Oelhaf, H.; Orphal, J.; Riese, M.; Schardt, G.; Schillings, J.; Sha, M. K.; Suminska-Ebersoldt, O.; Ungermann, J.

    2014-10-01

    The Gimballed Limb Observer for Radiance Imaging of the Atmosphere (GLORIA) is an imaging limb emission sounder operating in the thermal infrared region. It is designed to provide measurements of the upper troposphere/lower stratosphere with high spatial and high spectral resolution. The instrument consists of an imaging Fourier transform spectrometer integrated into a gimbal. The assembly can be mounted in the belly pod of the German High Altitude and Long Range research aircraft (HALO) and in instrument bays of the Russian M55 Geophysica. Measurements are made in two distinct modes: the chemistry mode emphasises chemical analysis with high spectral resolution, and the dynamics mode focuses on dynamical processes of the atmosphere with very high spatial resolution. In addition, the instrument allows tomographic analyses of air volumes. The first measurement campaigns have shown compliance with key performance and operational requirements.

  19. Medical image processing using transient Fourier holography in bacteriorhodopsin films

    NASA Astrophysics Data System (ADS)

    Kothapalli, Sri-Rajasekhar; Wu, Pengfei; Yelleswarapu, Chandra S.; Rao, D. V. G. L. N.

    2004-12-01

    Real time image processing is demonstrated by recording and reconstructing the transient photoisomerizative grating formed in the bR film using Fourier holography. Desired spatial frequencies including both high and low band in the object beam are reconstructed by controlling the reference beam intensity. The results are in agreement with a theoretical model based on photoisomerization grating. We exploit this technique to process mammograms in real-time for identification of microcalcifications buried in the soft tissue for early detection of breast cancer. A feature of the technique is the ability to transient display of selected spatial frequencies in the reconstructing process which enables the radiologists to study the features of interest.

  20. An image hiding method based on cascaded iterative Fourier transform and public-key encryption algorithm

    NASA Astrophysics Data System (ADS)

    Zhang, B.; Sang, Jun; Alam, Mohammad S.

    2013-03-01

    An image hiding method based on cascaded iterative Fourier transform and public-key encryption algorithm was proposed. Firstly, the original secret image was encrypted into two phase-only masks M1 and M2 via cascaded iterative Fourier transform (CIFT) algorithm. Then, the public-key encryption algorithm RSA was adopted to encrypt M2 into M2' . Finally, a host image was enlarged by extending one pixel into 2×2 pixels and each element in M1 and M2' was multiplied with a superimposition coefficient and added to or subtracted from two different elements in the 2×2 pixels of the enlarged host image. To recover the secret image from the stego-image, the two masks were extracted from the stego-image without the original host image. By applying public-key encryption algorithm, the key distribution was facilitated, and also compared with the image hiding method based on optical interference, the proposed method may reach higher robustness by employing the characteristics of the CIFT algorithm. Computer simulations show that this method has good robustness against image processing.

  1. Fourier-processed images of dynamic lung function from list-mode data

    SciTech Connect

    Zubal, I.G.; Rowe, R.W.; Bizais, Y.; Susskind, H.; Bennett, G.W.; Brill, A.B.

    1983-01-01

    Time and volume correlated amplitude and phase images are computed from nuclear medical ventilation studies and for dynamic transmission scans of the lungs. This is made possible by a hardware interface and data acquisition system, developed in-house, allowing camera events and multiple ancillary physiological signals (including lung volume) to be acquired simultaneously in list mode. The first harmonic amplitude and phase images are constructed on an event by event basis. These are computed for both equal time and equal lung volume increments. Time and volume correlated Fourier images for ventilation studies have shown details and functional structures not usually seen in conventional imaging techniques. Processed transmission scans show similar results compared to ventilation images.

  2. Non-iterative determination of pattern phase in structured illumination microscopy using auto-correlations in Fourier space.

    PubMed

    Wicker, Kai

    2013-10-21

    The artefact-free reconstruction of structured illumination microscopy images requires precise knowledge of the pattern phases in the raw images. If this parameter cannot be controlled precisely enough in an experimental setup, the phases have to be determined a posteriori from the acquired data. While an iterative optimisation based on cross-correlations between individual Fourier images yields accurate results, it is rather time-consuming. Here I present a fast non-iterative technique which determines each pattern phase from an auto-correlation of the respective Fourier image. In addition to improving the speed of the reconstruction, simulations show that this method is also more robust, yielding errors of typically less than ?/500 under realistic signal-to-noise levels. PMID:24150313

  3. Using a piezoelectric fiber stretcher to remove the depth ambiguity in optical Fourier domain imaging

    NASA Astrophysics Data System (ADS)

    Vergnole, Sébastien; Lamouche, Guy; Dufour, Marc; Gauthier, Bruno

    2007-07-01

    This paper reports the study of an Optical Fourier Domain Imaging (OFDI) setup for optical coherence tomography. One of the main drawbacks of OFDI is its inability to differentiate positive and negative depths. Some setups have already been proposed to remove this depth ambiguity by introducing a modulation by means of electro-optic or acousto-optic modulators. In our setup, we implement a piezoelectric fiber stretcher to generate a periodic phase shift between successive A-scans, thus introducing a transverse modulation. The depth ambiguity is then resolved by performing a Fourier treatment in the transverse direction before processing the data in the axial direction. It is similar to the B-M mode scanning already proposed for Spectral-Domain OCT1 but with a more efficient experimental setup. We discuss the advantages and the drawbacks of our technique compared to the technique based on acousto-optics modulators by comparing images of an onion obtained with both techniques.

  4. Integrated photoelasticity through imaging fourier polarimetry of an elliptic retarder.

    PubMed

    Berezhna, S; Berezhnyy, I; Takashi, M

    2001-02-10

    It is shown that three optical parameters that are necessary for stress computation in integrated photoelasticity can be measured with high accuracy by use of a Fourier polarimetry method. Inasmuch as a photoelastic sample, which is an object of investigation in integrated photoelasticity, is a kind of an elliptic retarder, the technique presented here measures relative retardation delta, azimuth angle theta, and ellipticity angle epsilon instead of the characteristic parameters that traditionally have been used in integrated photoelasticity. The ability of the new technique to provide better accuracy with a simpler setup has been proved experimentally. Furthermore, the technique is self-contained as for phase measurement; i.e., it automatically performs phase unwrapping at the points where phase data exceed the value of pi. The full value of a phase at a certain point is retrieved by processing of pi-modulo phase data that have been precisely measured at several wavelengths. The usefulness of the new method for integrated photoelasticity has been demonstrated through measurement of a diametrically compressed disk viewed at oblique light incidence. PMID:18357041

  5. Reconstruction of magnetic domain structure using the reverse Monte Carlo method with an extended Fourier image

    NASA Astrophysics Data System (ADS)

    Tokii, Maki; Kita, Eiji; Mitsumata, Chiharu; Ono, Kanta; Yanagihara, Hideto; Matsumoto, Makoto

    2015-05-01

    Visualization of the magnetic domain structure is indispensable to the investigation of magnetization processes and the coercivity mechanism. It is necessary to develop a reconstruction method from the reciprocal-space image to the real-space image. For this purpose, it is necessary to solve the problem of missing phase information in the reciprocal-space image. We propose the method of extend Fourier image with mean-value padding to compensate for the phase information. We visualized the magnetic domain structure using the Reverse Monte Carlo method with simulated annealing to accelerate the calculation. With this technique, we demonstrated the restoration of the magnetic domain structure, obtained magnetization and magnetic domain width, and reproduced the characteristic form that constitutes a magnetic domain.

  6. Continued Development of a Planetary Imaging Fourier Transform Spectrometer (PIFTS)

    NASA Technical Reports Server (NTRS)

    Sromovsky, L. A.

    2002-01-01

    This report describes continued efforts to evaluate a breadboard of a Planetary Imaging Fourier Transform Spectrometer (PIFTS). The PIFTS breadboard was developed under prior PIDDP funding. That effort is described in the final report for NASA Grant NAG5-6248 and in two conference papers (Sromovsky et al. 2000; Revercomb et al. 2000). The PIFTS breadboard was designed for near-IR (1-5.2 micrometer imaging of planetary targets with spectral resolving powers of several hundred to several thousand, using an InSb detector array providing at least 64x64 pixels imaging detail. The major focus of the development effort was to combine existing technologies to produce a small and low power design compatible with a very low mass flyable instrument. The objective of this grant (NAG5-10729) was further characterization of the breadboard performance, including intercomparisons with the highly accurate non-imaging Advanced Emitted Radiance Interferometer (AERI) (Revercomb et al. 1994; Best et al. 1997).

  7. Phase Contrast Imaging

    SciTech Connect

    Menk, Ralf Hendrik

    2008-11-13

    All standard (medical) x-ray imaging technologies, rely primarily on the amplitude properties of the incident radiation, and do not depend on its phase. This is unchanged since the discovery by Roentgen that the intensity of an x-ray beam, as measured by the exposure on a film, was related to the relative transmission properties of an object. However, recently various imaging techniques have emerged which depend on the phase of the x-rays as well as the amplitude. Phase becomes important when the beam is coherent and the imaging system is sensitive to interference phenomena. Significant new advances have been made in coherent optic theory and techniques, which now promise phase information in medical imaging. The development of perfect crystal optics and the increasing availability of synchrotron radiation facilities have contributed to a significant increase in the application of phase based imaging in materials and life sciences. Unique source characteristics such as high intensity, monochromaticity, coherence and high collimating provide an ideal source for advanced imaging. Phase contrast imaging has been applied in both projection and computed tomography modes, and recent applications have been made in the field of medical imaging. Due to the underlying principle of X-ray detection conventional image receptors register only intensities of wave fields and not their phases. During the last decade basically five different methods were developed that translate the phase information into intensity variations. These methods are based on measuring the phase shift {phi} directly (using interference phenomena), the gradient {nabla}{sub {phi}}, or the Laplacian {nabla}{sup 2}{phi}. All three methods can be applied to polychromatic X-ray sources keeping in mind that the native source is synchrotron radiation, featuring monochromatic and reasonable coherent X-ray beams. Due to the vast difference in the coefficients that are driven absorption and phase effects (factor 1,000-10,000 in the energy range suitable for medical imaging) phase based imaging techniques are inherently extremely sensitive.

  8. Phase Contrast Imaging

    NASA Astrophysics Data System (ADS)

    Menk, Ralf Hendrik

    2008-11-01

    All standard (medical) x-ray imaging technologies, rely primarily on the amplitude properties of the incident radiation, and do not depend on its phase. This is unchanged since the discovery by Röntgen that the intensity of an x-ray beam, as measured by the exposure on a film, was related to the relative transmission properties of an object. However, recently various imaging techniques have emerged which depend on the phase of the x-rays as well as the amplitude. Phase becomes important when the beam is coherent and the imaging system is sensitive to interference phenomena. Significant new advances have been made in coherent optic theory and techniques, which now promise phase information in medical imaging. The development of perfect crystal optics and the increasing availability of synchrotron radiation facilities have contributed to a significant increase in the application of phase based imaging in materials and life sciences. Unique source characteristics such as high intensity, monochromaticity, coherence and high collimating provide an ideal source for advanced imaging. Phase contrast imaging has been applied in both projection and computed tomography modes, and recent applications have been made in the field of medical imaging. Due to the underlying principle of X-ray detection conventional image receptors register only intensities of wave fields and not their phases. During the last decade basically five different methods were developed that translate the phase information into intensity variations. These methods are based on measuring the phase shift φ directly (using interference phenomena), the gradient ∇φ, or the Laplacian ∇2 φ. All three methods can be applied to polychromatic X-ray sources keeping in mind that the native source is synchrotron radiation, featuring monochromatic and reasonable coherent X-ray beams. Due to the vast difference in the coefficients that are driven absorption and phase effects (factor 1,000-10,000 in the energy range suitable for medical imaging) phase based imaging techniques are inherently extremely sensitive.

  9. Analysis of the modulation efficiency of imaging Fourier transform spectrometers

    NASA Astrophysics Data System (ADS)

    Fu, Yan-peng; Li, Xun-niu; Zheng, Wei-jian; Liao, Ning-fang; Su, Jun-hong

    2013-08-01

    The concept of high-throughput imaging Fourier transform spectrometer is introduced. Starting from the principle of the lateral shearing interferometer, it analyses the decline reason for the signal modulation efficiency and theoretically analyses the several aspects of the surface errors of the plane mirror, the beamsplitter properties change and the incident light angle influence the modulation efficiency. Based on analysis results, some expressions of modulation efficiency are provided. Furthermore, the relationship between modulation efficiency and performance parameters is pointed out. The reasons for the interferometer signal modulation efficiency decline can contain the following several aspects: (1) the influence of the surface errors of the plane mirror, (2) the polarization state change because of the influence of the reflection and the transmission in the light incident process makes the signal modulation efficiency decline, (3) the influence of the incident light angle. The results show that: this class of system is inherently optomechanics robust, no-moving part system, simple and compact structure, easy assembly and adjustment, strong vibration resistance as well as high resolution and high-throughput. Our results will provide a theoretical and practical guide for studying, developing and engineering Michelson lateral shearing interference imaging spectrometers. It can be widely used in the long-wave infrared (LWIR) imaging spectrometer system for thermal infrared remote sensing community.

  10. Amplitude and phase fourier correlation of ``twin'' GC-spectra of fatty acids from sheep dairy

    NASA Astrophysics Data System (ADS)

    Teusdea, Alin C.; Gabor, Gianina; Hilma, Elena

    2012-08-01

    Authors present the discrimination performances of amplitude and phase-only Fourier correlation over the "twin" typed GC-spectra of sheep milk and ripened cheese. Therefore, in order to assess the most robust Fourier correlation method for the "twin" GC-spectra discrimination, the correlation matrix is built up over 17 analyzed GC-spectra in both amplitude and phase domains.

  11. Fourier optics analysis of phase-mask-based path-length-multiplexed optical coherence tomography.

    PubMed

    Yin, Biwei; Dwelle, Jordan; Wang, Bingqing; Wang, Tianyi; Feldman, Marc D; Rylander, Henry G; Milner, Thomas E

    2015-11-01

    Optical coherence tomography (OCT) is an imaging technique that constructs a depth-resolved image by measuring the optical path-length difference between broadband light backscattered from a sample and a reference surface. For many OCT sample arm optical configurations, sample illumination and backscattered light detection share a common path. When a phase mask is placed in the sample path, features in the detected signal are observed, which suggests that an analysis of a generic common path OCT imaging system is warranted. In this study, we present a Fourier optics analysis using a Fresnel diffraction approximation of an OCT system with a path-length-multiplexing element (PME) inserted in the sample arm optics. The analysis may be generalized for most phase-mask-based OCT systems. A radial-angle-diverse PME is analyzed in detail, and the point spread function, coherent transfer function, sensitivity of backscattering angular diversity detection, and signal formation in terms of sample spatial frequency are simulated and discussed. The analysis reveals important imaging features and application limitations of OCT imaging systems with a phase mask in the sample path optics. PMID:26560931

  12. Multiresolution graph Fourier transform for compression of piecewise smooth images.

    PubMed

    Hu, Wei; Cheung, Gene; Ortega, Antonio; Au, Oscar C

    2015-01-01

    Piecewise smooth (PWS) images (e.g., depth maps or animation images) contain unique signal characteristics such as sharp object boundaries and slowly varying interior surfaces. Leveraging on recent advances in graph signal processing, in this paper, we propose to compress the PWS images using suitable graph Fourier transforms (GFTs) to minimize the total signal representation cost of each pixel block, considering both the sparsity of the signal's transform coefficients and the compactness of transform description. Unlike fixed transforms, such as the discrete cosine transform, we can adapt GFT to a particular class of pixel blocks. In particular, we select one among a defined search space of GFTs to minimize total representation cost via our proposed algorithms, leveraging on graph optimization techniques, such as spectral clustering and minimum graph cuts. Furthermore, for practical implementation of GFT, we introduce two techniques to reduce computation complexity. First, at the encoder, we low-pass filter and downsample a high-resolution (HR) pixel block to obtain a low-resolution (LR) one, so that a LR-GFT can be employed. At the decoder, upsampling and interpolation are performed adaptively along HR boundaries coded using arithmetic edge coding, so that sharp object boundaries can be well preserved. Second, instead of computing GFT from a graph in real-time via eigen-decomposition, the most popular LR-GFTs are pre-computed and stored in a table for lookup during encoding and decoding. Using depth maps and computer-graphics images as examples of the PWS images, experimental results show that our proposed multiresolution-GFT scheme outperforms H.264 intra by 6.8 dB on average in peak signal-to-noise ratio at the same bit rate. PMID:25494508

  13. Comparison of kinoform synthesis methods for image reconstruction in Fourier plane

    NASA Astrophysics Data System (ADS)

    Cheremkhin, Pavel A.; Evtikhiev, Nikolay N.; Krasnov, Vitaly V.; Porshneva, Liudmila A.; Rodin, Vladislav G.; Starikov, Sergey N.

    2014-05-01

    Kinoform is synthesized phase diffractive optical element which allows to reconstruct image by its illumination with plane wave. Kinoforms are used in image processing systems. For tasks of kinoform synthesis iterative methods had become wide-spread because of relatively small error of resulting intensity distribution. There are articles in which two or three iterative methods are compared but they use only one or several test images. The goal of this work is to compare iterative methods by using many test images of different types. Images were reconstructed in Fourier plane from synthesized kinoforms displayed on phase-only LCOS SLM. Quality of reconstructed images and computational resources of the methods were analyzed. For kinoform synthesis four methods were implemented in programming environment: Gerchberg-Saxton algorithm (GS), Fienup algorithm (F), adaptive-additive algorithm (AA) and Gerchberg-Saxton algorithm with weight coefficients (GSW). To compare these methods 50 test images with different characteristics were used: binary and grayscale, contour and non-contour. Resolution of images varied from 64×64 to 1024×1024. Occupancy of images ranged from 0.008 to 0.89. Quantity of phase levels of synthesized kinoforms was 256 which is equal to number of phase levels of SLM LCOS HoloEye PLUTO VIS. Under numerical testing it was found that the best quality of reconstructed images provides the AA method. The GS, F and GSW methods showed worse results but roughly similar between each other. Execution time of single iteration of the analyzed methods is minimal for the GS method. The F method provides maximum execution time. Synthesized kinoforms were optically reconstructed using phase-only LCOS SLM HoloEye PLUTO VIS. Results of optical reconstruction were compared to the numerical ones. The AA method showed slightly better results than other methods especially in case of gray-scale images.

  14. Feasibility Demonstration of Wide-Field Fourier-Spectroscopic-Imaging in Infrared Region

    NASA Astrophysics Data System (ADS)

    Qi, Wei; Takuma, Takashi; Tsutsumi, Ryosuke; Inui, Asuka; Kagiyama, Hiroyasu; Kojima, Daisuke; Nishiyama, Akira; Ishimaru, Ichirou

    We are aiming at the realization of living-environment sensor and non-invasive blood-sugar sensor by the proposed imaging type 2-D Fourier spectroscopy. This method is based on the phase-shift interference between the object beams. As a result, even if the object beams are spatially incoherent, we can observe the phase-shift interference phenomena. In the near infrared region, we can obtain the high-contrast blood vessel image of mouse's ear in the deeper part by InGaAs camera. Furthermore, in the mid-infrared region, we have successfully measured the radiation spectroscopic-imaging with wild field of view by the infrared module, such as the house plants.

  15. Optimized multiplexing super resolution imaging based on a Fourier ptychographic microscope

    NASA Astrophysics Data System (ADS)

    Sun, Jiasong; Chen, Qian; Zhang, Yuzhen; Zuo, Chao; Feng, Shijie; Hu, Yan; Zhang, Jialin

    2015-10-01

    Fourier ptychographic microscopy (FPM) is a recently developed super-resolution technique by using angularly varying illumination and a phase retrieval algorithm to surpass the diffraction limit of the objective lens. To be specific, FP captures a set of low-resolution (LR) images under angularly varying illuminations, and combines them into one high-resolution (HR) image in the Fourier domain. However, the long capturing process becomes an obvious limitation since there are large number of images need to be acquired. Furthermore, the time can be increased several times over in order to acquire high-dynamic range images. Utilizing the multiplexing principle, we propose an optimized multiplexing FP algorithm, which is highly efficient, to shorten the exposure time of each raw image in this work. High acquisition efficiency is achieved by employing two set of optimized multiplexing patterns for bright-field and dark-field imaging respectively. Experimental results demonstrated that this method could improve the quality of reconstructed HR intensity distributions in a faster measuring process.

  16. Fractional Fourier plane image encryption technique using radial hilbert-, and Jigsaw transform

    NASA Astrophysics Data System (ADS)

    Joshi, Madhusudan; Shakher, Chandra; Singh, Kehar

    2010-07-01

    A new method for image encryption using integral order radial Hilbert transform (RHT) filter in the fractional Fourier transform (FRT) domain has been proposed. The technique is implemented using the popular double random phase encoding method in the fractional Fourier domain. The random phase masks (RPMs), integral orders of the RHT, fractional orders of FRT, and indices of the Jigsaw transform (JT) have been used as keys for encryption and decryption. Simulation results have been presented and the schematic representation for optical implementation has been proposed. The mean-square-error and signal-to-noise ratio between the decrypted image and the input image have been calculated for the correct as well as incorrect orders of the RHT. Effect of occlusion and noise on the performance of the proposed scheme has also been studied. The robustness of the technique has been verified against attack using partial windows of the correct random phase masks. Similar investigations have also been carried out for the chosen-, and the known-plain-text attacks.

  17. ULTRASOUND PULSE-ECHO IMAGING USING THE SPLIT-STEP FOURIER PROPAGATOR

    SciTech Connect

    HUANG, LIANJIE; QUAN, YOULI

    2007-01-31

    Ultrasonic reflection imaging has the potential to produce higher image resolution than transmission tomography, but imaging resolution and quality still need to be further improved for early cancer detection and diagnosis. We present an ultrasound reflection image reconstruction method using the split-step Fourier propagator. It is based on recursive inward continuation of ultrasonic wavefields in the frequency-space and frequency-wavenumber domains. The inward continuation within each extrapolation interval consists of two steps. In the first step, a phase-shift term is applied to the data in the frequency-wavenumber domain for propagation in a reference medium. The second step consists of applying another phase-shift term to data in the frequency-space domain to approximately compensate for ultrasonic scattering effects of heterogeneities within the breast. We use synthetic ultrasound pulse-echo data recorded around a ring for heterogeneous, computer-generated numerical breast phantoms to study the imaging capability of the method. The phantoms are derived from an experimental breast phantom and a sound-speed tomography image of an in-vivo ultrasound breast data collected usi ng a ring array. The heterogeneous sound-speed models used for pulse-echo imaging are obtained using a computationally efficient, first-arrival-time (time-of-flight) transmission tomography method. Our studies demonstrate that reflection image reconstruction using the split-step Fourier propagator with heterogeneous sound-speed models significantly improves image quality and resolution. We also numerically verify the spatial sampling criterion of wavefields for a ring transducer array.

  18. Multiple-image encryption scheme based on cascaded fractional Fourier transform.

    PubMed

    Kong, Dezhao; Shen, Xueju; Xu, Qinzu; Xin, Wang; Guo, Haiqiong

    2013-04-20

    A multiple-image encryption scheme based on cascaded fractional Fourier transform is proposed. In the scheme, images are successively coded into the amplitude and phase of the input by cascading stages, which ends up with an encrypted image and a series of keys. The scheme takes full advantage of multikeys and the cascaded relationships of all stages, and it not only realizes image encryption but also achieves higher safety and more diverse applications. So multiuser authentication and hierarchical encryption are achieved. Numerical simulation verifies the feasibility of the method and demonstrates the security of the scheme and decryption characteristics. Finally, flexibility and variability of the scheme in application are discussed, and the simple photoelectric mixed devices to realize the scheme are proposed. PMID:23669669

  19. Ghost imaging of phase objects with classical incoherent light

    SciTech Connect

    Shirai, Tomohiro; Setaelae, Tero; Friberg, Ari T.

    2011-10-15

    We describe an optical setup for performing spatial Fourier filtering in ghost imaging with classical incoherent light. This is achieved by a modification of the conventional geometry for lensless ghost imaging. It is shown on the basis of classical coherence theory that with this technique one can realize what we call phase-contrast ghost imaging to visualize pure phase objects.

  20. Discussion and a new attack of the optical asymmetric cryptosystem based on phase-truncated Fourier transform.

    PubMed

    Wang, Xiaogang; Chen, Yixiang; Dai, Chaoqing; Zhao, Daomu

    2014-01-10

    A discussion and a cryptanalysis of the optical phase-truncated Fourier-transform-based cryptosystem are presented in this paper. The concept of an optical asymmetric cryptosystem, which was introduced into the optical image encryption scheme based on phase-truncated Fourier transforms in 2010, is suggested to be retained in optical encryption. A new method of attack is also proposed to simultaneously obtain the main information of the original image, the two decryption keys from its cyphertext, and the public keys based on the modified amplitude-phase retrieval algorithm. The numerical results illustrate that the computing efficiency of the algorithm is improved and the number of iterations is much less than that by the specific attack, which has two iteration loops. PMID:24514051

  1. Image encryption based on nonseparable fractional Fourier transform and chaotic map

    NASA Astrophysics Data System (ADS)

    Ran, Qiwen; Yuan, Lin; Zhao, Tieyu

    2015-08-01

    In this paper an image cryptosystem is constructed by using double random phase masks and a chaotic map together with a novel transform which is similar to fractional Fourier transform and gyrator transform to some extent. The new transform is not periodic with respect to the transform order and cannot be expressed as a tensor product of two one-dimensional transforms neither in the space domain nor in the Wigner space-frequency domain. In the cryptosystem, the parameters of Arnold map, transform orders of the proposed transform and phase information serve as the main keys. The numerical simulations have demonstrated the validity and high security level of the image cryptosystem based on the proposed transform.

  2. Single-point (constant-time) imaging in radiofrequency Fourier transform electron paramagnetic resonance.

    PubMed

    Subramanian, Sankaran; Devasahayam, Nallathamby; Murugesan, Ramachandran; Yamada, Kenichi; Cook, John; Taube, Andrew; Mitchell, James B; Lohman, Joost A B; Krishna, Murali C

    2002-08-01

    This study describes the use of the single-point imaging (SPI) modality, also known as constant-time imaging (CTI), in radiofrequency (RF) Fourier transform (FT) electron paramagnetic resonance (EPR). The SPI technique, commonly used for high-resolution solid-state nuclear magnetic resonance (NMR) imaging, has been successfully applied to 2D and 3D RF-FT-EPR imaging of phantoms containing narrow-line EPR spin probes. The SPI scheme is essentially a phase-encoding technique that operates by acquiring a single data point in the free induction decay (FID) after a fixed delay (phase-encoding time), following the pulsed RF excitation, in the presence of static magnetic field gradients. Since the phase-encoding time remains constant for a given image data set, the spectral information is automatically deconvolved, providing well-resolved pure spatial images. Therefore, images obtained using SPI are artifact-free and the resolution is not significantly limited by the line width, compared to the images obtained using the conventional filtered back-projection (FBP) scheme, suggesting that the SPI modality may have advantages for EPR imaging of large objects. In this work the advantages and limitations of SPI as compared to FBP are investigated by imaging suitable phantom objects. Although SPI takes longer to perform than the FBP method, optimization of the data collection scheme may increase the temporal resolution, rendering this technique suitable for in vivo studies. Spectral information can also be extracted from a series of SPI images that are generated as a function of the delay from the excitation pulse. PMID:12210946

  3. High-resolution wave-theory-based ultrasound reflection imaging using the split-step fourier and globally optimized fourier finite-difference methods

    DOEpatents

    Huang, Lianjie

    2013-10-29

    Methods for enhancing ultrasonic reflection imaging are taught utilizing a split-step Fourier propagator in which the reconstruction is based on recursive inward continuation of ultrasonic wavefields in the frequency-space and frequency-wave number domains. The inward continuation within each extrapolation interval consists of two steps. In the first step, a phase-shift term is applied to the data in the frequency-wave number domain for propagation in a reference medium. The second step consists of applying another phase-shift term to data in the frequency-space domain to approximately compensate for ultrasonic scattering effects of heterogeneities within the tissue being imaged (e.g., breast tissue). Results from various data input to the method indicate significant improvements are provided in both image quality and resolution.

  4. Palm-size wide-field Fourier spectroscopic imager with uncooled infrared microbolometer arrays for smartphone

    NASA Astrophysics Data System (ADS)

    Kawashima, Natsumi; Suzuki, Yo; Qi, Wei; Hosono, Satsuki; Saito, Tsubasa; Ogawa, Satoshi; Sato, Shun; Fujiwara, Masaru; Nishiyama, Akira; Wada, Kenji; Tanaka, Naotaka; Ishimaru, Ichiro

    2015-03-01

    We proposed the imaging-type 2-dimensional Fourier spectroscopy that is a near-common-path interferometer with strong robustness against mechanical vibrations. We introduced the miniature uncooled infrared microbolometer arrays for smartphone (e.g. product name: FILR ONE price: around 400USD). And we constructed the phase-shifter with the piezo impact drive mechanism (maker: Technohands.co.Ltd., stroke: 4.5mm, resolution: 0.01μm, size: 20mm, price: around 800USD). Thus, we realized the palm-size mid-infrared spectroscopic imager [size: L56mm×W69mm×H43mm weight: 500g]. And by using wide-angle lens as objective lens, the proposed method can obtain the wide-field 2- dimensional middle-infrared (wavelength: 7.5-13.5[μm]) spectroscopic imaging of radiation lights emitted from human bodies itself

  5. In-orbit performance of the Herschel/SPIRE imaging Fourier transform spectrometer: lessons learned

    NASA Astrophysics Data System (ADS)

    Naylor, David A.; Baluteau, Jean-Paul; Bendo, George J.; Benielli, Dominique; Fulton, Trevor R.; Gom, Brad G.; Griffin, Matthew J.; Hopwood, Rosalind; Imhof, Peter; Lim, Tanya L.; Lu, Nanyao; Makiwa, Gibion; Marchili, Nicola; Orton, Glenn S.; Papageorgiou, Andreas; Pearson, Chris; Polehampton, Edward T.; Schulz, Bernhard; Spencer, Locke D.; Swinyard, Bruce M.; Valtchanov, Ivan; van der Wiel, Matthijs H. D.; Veenendaal, Ian T.; Wu, Ronin

    2014-08-01

    The Spectral and Photometric Imaging Receiver (SPIRE) is one of three scientific instruments on board the European Space Agency's Herschel Space Observatory which ended its operational phase on 29 April 2013. The low to medium resolution spectroscopic capability of SPIRE is provided by an imaging Fourier transform spectrometer (iFTS) of the Mach-Zehnder configuration. With their high throughput, broad spectral coverage, and variable resolution, coupled with their well-defined instrumental line shape and intrinsic wavelength and intensity calibration, iFTS are becoming increasingly common in far-infrared space astronomy missions. The performance of the SPIRE imaging spectrometer will be reviewed and example results presented. The lessons learned from the measured performance of the spectrometer as they apply to future missions will be discussed.

  6. Geostationary Imaging Fourier Transform Spectrometer (GIFTS): science applications

    NASA Astrophysics Data System (ADS)

    Smith, W. L.; Revercomb, H. E.; Zhou, D. K.; Bingham, G. E.; Feltz, W. F.; Huang, H. L.; Knuteson, R. O.; Larar, A. M.; Liu, X.; Reisse, R.; Tobin, D. C.

    2006-12-01

    A revolutionary satellite weather forecasting instrument, called the "GIFTS" which stands for the "Geostationary Imaging Fourier Transform Spectrometer", was recently completed and successfully tested in a space chamber at the Utah State University's Space Dynamics Laboratory. The GIFTS was originally proposed by the NASA Langley Research Center, the University of Wisconsin, and the Utah State University and selected for flight demonstration as NASA's New Millennium Program (NMP) Earth Observing-3 (EO-3) mission, which was unfortunately cancelled in 2004. GIFTS is like a digital 3-d movie camera that, when mounted on a geostationary satellite, would provide from space a revolutionary four-dimensional view of the Earth's atmosphere. GIFTS will measure the distribution, change, and movement of atmospheric moisture, temperature, and certain pollutant gases, such as carbon monoxide and ozone. The observation of the convergence of invisible water vapor, and the change of atmospheric temperature, provides meteorologists with the observations needed to predict where, and when, severe thunderstorms, and possibly tornados, would occur, before they are visible on radar or in satellite cloud imagery. The ability of GIFTS to observe the motion of moisture and clouds at different altitudes enables atmospheric winds to be observed over vast, and otherwise data sparse, oceanic regions of the globe. These wind observations would provide the means to greatly improve the forecast of where tropical storms and hurricanes will move and where and when they will come ashore (i.e., their landfall position and time). GIFTS, if flown into geostationary orbit, would provide about 80,000 vertical profiles per minute, each one like a low vertical resolution (1-2km) weather balloon sounding, but with a spacing of 4 km. GIFTS is a revolutionary atmospheric sensing tool. A glimpse of the science measurement capabilities of GIFTS is provided through airborne measurements with the NPOESS Airborne Sounding Testbed - Interferometer (NAST-I).

  7. Rotational-translational fourier imaging system requiring only one grid pair

    NASA Technical Reports Server (NTRS)

    Campbell, Jonathan W. (Inventor)

    2006-01-01

    The sky contains many active sources that emit X-rays, gamma rays, and neutrons. Unfortunately hard X-rays, gamma rays, and neutrons cannot be imaged by conventional optics. This obstacle led to the development of Fourier imaging systems. In early approaches, multiple grid pairs were necessary in order to create rudimentary Fourier imaging systems. At least one set of grid pairs was required to provide multiple real components of a Fourier derived image, and another set was required to provide multiple imaginary components of the image. It has long been recognized that the expense associated with the physical production of the numerous grid pairs required for Fourier imaging was a drawback. Herein one grid pair (two grids), with accompanying rotation and translation, can be used if one grid has one more slit than the other grid, and if the detector is modified.

  8. Vector power multiple-parameter fractional Fourier transform of image encryption algorithm

    NASA Astrophysics Data System (ADS)

    Ran, Qiwen; Zhao, Tieyu; Yuan, Lin; Wang, Jian; Xu, Lei

    2014-11-01

    In this paper, we propose a multiple-parameter fractional Fourier transform with its transform order being a real vector, based on which a high-security image encryption scheme is also given. This novel fractional Fourier transform has removed the restriction on the dimension of transform order and highly enhances the security of image encryption scheme proposed in this paper without increasing the computational complexity and hardware cost. The numerical results verify the efficacy and security of this image encryption method. The vector power multi-parameter fractional Fourier transform is a generalized form of the classical fractional Fourier transform with all the previous fractional Fourier transform as its special cases and has theoretical significance in information processing and information security.

  9. The Pegg-Barnett phase operator and the discrete Fourier transform

    NASA Astrophysics Data System (ADS)

    Perez-Leija, Armando; Andrade-Morales, Luis A.; Soto-Eguibar, Francisco; Szameit, Alexander; Moya-Cessa, Héctor M.

    2016-04-01

    In quantum mechanics the position and momentum operators are related to each other via the Fourier transform. In the same way, here we show that the so-called Pegg-Barnett phase operator can be obtained by the application of the discrete Fourier transform to the number operators defined in a finite-dimensional Hilbert space. Furthermore, we show that the structure of the London-Susskind-Glogower phase operator, whose natural logarithm gives rise to the Pegg-Barnett phase operator, is contained in the Hamiltonian of circular waveguide arrays. Our results may find applications in the development of new finite-dimensional photonic systems with interesting phase-dependent properties.

  10. Fourier magnetic imaging with nanoscale resolution and compressed sensing speed-up using electronic spins in diamond

    NASA Astrophysics Data System (ADS)

    Arai, Keigo; Belthangady, Chinmay; Zhang, Huiliang; Devience, Stephen; Bar-Gill, Nir; Cappellaro, Paola; Yacoby, Amir; Walsworth, Ronald

    2015-05-01

    Optically-detected magnetic resonance using nitrogen vacancy (NV) color centers in diamond is playing a leading role in nanoscale magnetic field imaging of various physical and biological samples at room temperature. NV magnetic imaging techniques to date, however, are based on ``real space'' detection, which is either limited by optical diffraction or requires slow scanning for nanometer-scale resolution. Here we present an alternative approach of NV Fourier magnetic imaging. By employing pulsed magnetic field gradients, spatial information about the NV centers as well as the local magnetic field are phase-encoded in wavenumber or ``k-space.'' A Fourier transform then yields real-space images with nanoscale resolution, wide field-of-view, and compressed sensing speed-up.

  11. Wide field-of-view fluorescence image deconvolution with aberration-estimation from Fourier ptychography.

    PubMed

    Chung, Jaebum; Kim, Jinho; Ou, Xiaoze; Horstmeyer, Roarke; Yang, Changhuei

    2016-02-01

    This paper presents a method to simultaneously acquire an aberration-corrected, wide field-of-view fluorescence image and a high-resolution coherent bright-field image using a computational microscopy method. First, the procedure applies Fourier ptychographic microscopy (FPM) to retrieve the amplitude and phase of a sample, at a resolution that significantly exceeds the cutoff spatial frequency of the microscope objective lens. At the same time, redundancy within the set of acquired FPM bright-field images offers a means to estimate microscope aberrations. Second, the procedure acquires an aberrated fluorescence image, and computationally improves its resolution through deconvolution with the estimated aberration map. An experimental demonstration successfully improves the bright-field resolution of fixed, stained and fluorescently tagged HeLa cells by a factor of 4.9, and reduces the error caused by aberrations in a fluorescence image by up to 31%, over a field of view of 6.2 mm by 9.3 mm. For optimal deconvolution, we show the fluorescence image needs to have a signal-to-noise ratio of at least ~18. PMID:26977345

  12. Wide field-of-view fluorescence image deconvolution with aberration-estimation from Fourier ptychography

    PubMed Central

    Chung, Jaebum; Kim, Jinho; Ou, Xiaoze; Horstmeyer, Roarke; Yang, Changhuei

    2016-01-01

    This paper presents a method to simultaneously acquire an aberration-corrected, wide field-of-view fluorescence image and a high-resolution coherent bright-field image using a computational microscopy method. First, the procedure applies Fourier ptychographic microscopy (FPM) to retrieve the amplitude and phase of a sample, at a resolution that significantly exceeds the cutoff spatial frequency of the microscope objective lens. At the same time, redundancy within the set of acquired FPM bright-field images offers a means to estimate microscope aberrations. Second, the procedure acquires an aberrated fluorescence image, and computationally improves its resolution through deconvolution with the estimated aberration map. An experimental demonstration successfully improves the bright-field resolution of fixed, stained and fluorescently tagged HeLa cells by a factor of 4.9, and reduces the error caused by aberrations in a fluorescence image by up to 31%, over a field of view of 6.2 mm by 9.3 mm. For optimal deconvolution, we show the fluorescence image needs to have a signal-to-noise ratio of at least ~18. PMID:26977345

  13. New 2D discrete Fourier transforms in image processing

    NASA Astrophysics Data System (ADS)

    Grigoryan, Artyom M.; Agaian, Sos S.

    2015-03-01

    In this paper, the concept of the two-dimensional discrete Fourier transformation (2-D DFT) is defined in the general case, when the form of relation between the spatial-points (x, y) and frequency-points (ω1, ω2) is defined in the exponential kernel of the transformation by a nonlinear form L(x, y; ω1, ω2). The traditional concept of the 2-D DFT uses the Diaphanous form xω1 +yω2 and this 2-D DFT is the particular case of the Fourier transform described by the form L(x, y; ω1, ω2). Properties of the general 2-D discrete Fourier transform are described and examples are given. The special case of the N × N-point 2-D Fourier transforms, when N = 2r, r > 1, is analyzed and effective representation of these transforms is proposed. The proposed concept of nonlinear forms can be also applied for other transformations such as Hartley, Hadamard, and cosine transformations.

  14. Spatial Phase Imaging

    NASA Technical Reports Server (NTRS)

    2006-01-01

    Frequently, scientists grow crystals by dissolving a protein in a specific liquid solution, and then allowing that solution to evaporate. The methods used next have been, variously, invasive (adding a dye that is absorbed by the protein), destructive (crushing protein/salt-crystal mixtures and observing differences between the crushing of salt and protein), or costly and time-consuming (X-ray crystallography). In contrast to these methods, a new technology for monitoring protein growth, developed in part through NASA Small Business Innovation Research (SBIR) funding from Marshall Space Flight Center, is noninvasive, nondestructive, rapid, and more cost effective than X-ray analysis. The partner for this SBIR, Photon-X, Inc., of Huntsville, Alabama, developed spatial phase imaging technology that can monitor crystal growth in real time and in an automated mode. Spatial phase imaging scans for flaws quickly and produces a 3-D structured image of a crystal, showing volumetric growth analysis for future automated growth.

  15. Complete fourier direct magnetic resonance imaging (CFD-MRI) for diffusion MRI

    PubMed Central

    Özcan, Alpay

    2013-01-01

    The foundation for an accurate and unifying Fourier-based theory of diffusion weighted magnetic resonance imaging (DW–MRI) is constructed by carefully re-examining the first principles of DW–MRI signal formation and deriving its mathematical model from scratch. The derivations are specifically obtained for DW–MRI signal by including all of its elements (e.g., imaging gradients) using complex values. Particle methods are utilized in contrast to conventional partial differential equations approach. The signal is shown to be the Fourier transform of the joint distribution of number of the magnetic moments (at a given location at the initial time) and magnetic moment displacement integrals. In effect, the k-space is augmented by three more dimensions, corresponding to the frequency variables dual to displacement integral vectors. The joint distribution function is recovered by applying the Fourier transform to the complete high-dimensional data set. In the process, to obtain a physically meaningful real valued distribution function, phase corrections are applied for the re-establishment of Hermitian symmetry in the signal. Consequently, the method is fully unconstrained and directly presents the distribution of displacement integrals without any assumptions such as symmetry or Markovian property. The joint distribution function is visualized with isosurfaces, which describe the displacement integrals, overlaid on the distribution map of the number of magnetic moments with low mobility. The model provides an accurate description of the molecular motion measurements via DW–MRI. The improvement of the characterization of tissue microstructure leads to a better localization, detection and assessment of biological properties such as white matter integrity. The results are demonstrated on the experimental data obtained from an ex vivo baboon brain. PMID:23596401

  16. Discovering ordered phases of block copolymers: new results from a generic Fourier-space approach.

    PubMed

    Guo, Zuojun; Zhang, Guojie; Qiu, Feng; Zhang, Hongdong; Yang, Yuliang; Shi, An-Chang

    2008-07-11

    A generic Fourier-space approach to solve the self-consistent field theory of block copolymers is developed. This approach is based on the fact that, for any computational box with periodic boundary conditions, all spatially varying functions are spanned by the Fourier series determined by the size and shape of the box. The method reproduces all known diblock copolymer phases. The application of this method to a model "frustrated" triblock copolymer leads to a phase diagram with a number of new phases. Furthermore, the capability of the method to reproduce experimentally observed structures is demonstrated using the knitting pattern of triblock copolymers. PMID:18764231

  17. Single-Grid-Pair Fourier Telescope for Imaging in Hard-X Rays and gamma Rays

    NASA Technical Reports Server (NTRS)

    Campbell, Jonathan

    2008-01-01

    This instrument, a proposed Fourier telescope for imaging in hard-x rays and gamma rays, would contain only one pair of grids made of an appropriate radiation-absorpting/ scattering material, in contradistinction to multiple pairs of such as grids in prior Fourier x- and gamma-ray telescopes. This instrument would also include a relatively coarse gridlike image detector appropriate to the radiant flux to be imaged. Notwithstanding the smaller number of grids and the relative coarseness of the imaging detector, the images produced by the proposed instrument would be of higher quality.

  18. Avalanche and bit independence characteristics of double random phase encoding in the Fourier and Fresnel domains.

    PubMed

    Moon, Inkyu; Yi, Faliu; Lee, Yeon H; Javidi, Bahram

    2014-05-01

    In this work, we evaluate the avalanche effect and bit independence properties of the double random phase encoding (DRPE) algorithm in the Fourier and Fresnel domains. Experimental results show that DRPE has excellent bit independence characteristics in both the Fourier and Fresnel domains. However, DRPE achieves better avalanche effect results in the Fresnel domain than in the Fourier domain. DRPE gives especially poor avalanche effect results in the Fourier domain when only one bit is changed in the plaintext or in the encryption key. Despite this, DRPE shows satisfactory avalanche effect results in the Fresnel domain when any other number of bits changes in the plaintext or in the encryption key. To the best of our knowledge, this is the first report on the avalanche effect and bit independence behaviors of optical encryption approaches for bit units. PMID:24979643

  19. Optical Fourier and Holographic Techniques for Medical Image Processing with Bacteriorhodopsin

    NASA Astrophysics Data System (ADS)

    Yelleswarapu, Chandra

    2008-03-01

    The biological photochrome bacteriorhodopsin (bR) shows many intrinsic optical and physical properties. The active chromophore in bR is a retinal group which absorbs light and goes through a photocycle. The unique feature of the system is its flexibility -- the photocycle can be optically controllable since the process of photoisomerization can go in both directions depending on wavelength, intensity and polarization of the incident light, opening a variety of possibilities for manipulating amplitude, phase, polarization and index of refraction of the incident light. Over the years we studied the basic nonlinear optics and successfully exploited the unique properties for several optical spatial filtering techniques with applications in medical image processing. For nonlinear Fourier filtering, the photo-controlled light modulating characteristics of bR films are exploited. At the Fourier plane, the spatial frequency information carried by a blue probe beam at 442 nm is selectively manipulated in the bR film by changing the position and intensity of a yellow control beam at 568 nm. In transient Fourier holography, photoisomerizative gratings are recorded and reconstructed in bR films. Desired spatial frequencies are obtained by matching the reference beam intensity to that of the particular frequency band in object beam. A novel feature of the technique is the ability to transient display of selected spatial frequencies in the reconstructing process which enables radiologists to study the features of interest in time scale. The results offer useful information to radiologists for early detection of breast cancer. Some of the highlights will be presented.

  20. Coherent events in the phase of the Fourier spectrum of isotropic 2D turbulence

    NASA Astrophysics Data System (ADS)

    Reynolds-Barredo, Jose-Miguel; Newman, David E.; Terry, Paul W.; Sanchez, Raul

    2015-11-01

    While studying turbulence it is common to analyze the Fourier transform of the evolved fields. However, most of these studies focus only on the amplitude of the Fourier transform, completely ignoring the complex phase. From the time of Kolmogorov, the slopes of the power spectrum have been extensively investigated. In contrast, studies of the phase are scarce, mainly due to the difficulties of its interpretation. Here, we continue previous studies on a 2D plasma turbulence model in which we showed that clear coherent patterns do appear in the complex phase of the Fourier spectrum, mainly within the dissipation range. These events have been shown to be associated with intermittent structures in real space. In this contribution, these results have also been obtained using the more general case of 2D incompressible Navier-Stokes equations, including different types of dissipation. The conclusions of our previous work remain in the sense that the coherent events continue to appear intermittently in the phase, being rather insensitive to the particular details of the model. This is the first time that such clear coherence patterns have been identified in the phase of the Fourier spectrum for a turbulence simulation. The work was sopported in part by the Spanish project ENE2012-33219.

  1. Optical encryption by combining image scrambling techniques in fractional Fourier domains

    NASA Astrophysics Data System (ADS)

    Liu, Shi; Sheridan, John T.

    2013-01-01

    In this paper, we propose a novel scheme for optical information hiding (encryption) of two-dimensional images by combining image scrambling techniques in fractional Fourier domains. The image is initially randomly shifted using the jigsaw transform algorithm, and then a pixel scrambling technique based on the Arnold transform (ART) is applied. The scrambled image is then encrypted in a randomly chosen fractional Fourier domain. These processes can then be iteratively repeated. The parameters of the architecture, including the jigsaw permutation indices, Arnold frequencies, and fractional Fourier orders, form a very large key space enhancing the security level of the proposed encryption system. Optical implementations are discussed as numerical implementation algorithms. Numerical simulation results are presented to demonstrate the system's flexibility and robustness.

  2. Real-time generation of atmospheric turbulence phase screen with non-uniform fast Fourier transform

    NASA Astrophysics Data System (ADS)

    Jia, Peng; Cai, Dongmei; Wang, Dong; Basden, Alastair

    2015-06-01

    High-fidelity Monte Carlo simulation of atmospheric turbulence phase screens is important for performance testing of astronomical adaptive optics systems. With a sparse spectrum model and an optimal sampling method, it is possible to generate an atmospheric turbulence phase screen with high fidelity. However, the phase screen generation speed is limited by the algorithm structure of this technique. A non-uniform fast Fourier transform technique is proposed in this paper to accelerate phase screen generation speed. This method is able to generate huge atmospheric turbulence phase screens with high fidelity and an acceptable time-cost enabling practical adaptive optics simulations of forthcoming Extremely Large Telescopes.

  3. Implementation and assessment of diffusion-weighted partial Fourier readout-segmented echo-planar imaging.

    PubMed

    Frost, Robert; Porter, David A; Miller, Karla L; Jezzard, Peter

    2012-08-01

    Single-shot echo-planar imaging has been used widely in diffusion magnetic resonance imaging due to the difficulties in correcting motion-induced phase corruption in multishot data. Readout-segmented EPI has addressed the multishot problem by introducing a two-dimensional nonlinear navigator correction with online reacquisition of uncorrectable data to enable acquisition of high-resolution diffusion data with reduced susceptibility artifact and T*(2) blurring. The primary shortcoming of readout-segmented EPI in its current form is its long acquisition time (longer than similar resolution single-shot echo-planar imaging protocols by approximately the number of readout segments), which limits the number of diffusion directions. By omitting readout segments at one side of k-space and using partial Fourier reconstruction, readout-segmented EPI imaging times could be reduced. In this study, the effects of homodyne and projection onto convex sets reconstructions on estimates of the fractional anisotropy, mean diffusivity, and diffusion orientation in fiber tracts and raw T(2)- and trace-weighted signal are compared, along with signal-to-noise ratio results. It is found that projections onto convex sets reconstruction with 3/5 segments in a 2 mm isotropic diffusion tensor image acquisition and 9/13 segments in a 0.9 × 0.9 × 4.0 mm(3) diffusion-weighted image acquisition provide good fidelity relative to the full k-space parameters. This allows application of readout-segmented EPI to tractography studies, and clinical stroke and oncology protocols. PMID:22535706

  4. Ultrasound imaging of long bone fractures and healing with the split-step fourier imaging method.

    PubMed

    Li, Hongjiang; Le, Lawrence H; Sacchi, Mauricio D; Lou, Edmond H M

    2013-08-01

    We applied the split-step Fourier imaging method to back-propagate the ultrasound zero-offset wavefields acquired on the bone surface to the sources of scatterers, which are the reflecting interfaces. The method required, as an input, an estimated slowness (reciprocal of half the velocity) model to map the time-dependent sonogram to the depth image, which provides the geometric properties of the interfaces. The slowness was approximated by a depth-dependent term and a first-order spatially varying perturbation. Simulated data sets were used to validate the method. The reconstructed images show proper mapping of the interfaces and the fracture, and a reasonable cortical thickness measurement with 8.3% error. The images also illustrate clearly the bone fracture healing process of a 1-mm-wide 45° inclined crack with different in-filled tissue velocities for various healing stages. Reconstruction of a fractured bone plate using data from an in vitro experiment is also presented. This study suggests that the proposed imaging method has good potential in quantification of bone fractures and monitoring of the fracture healing process. PMID:23838363

  5. Fabrication and Testing of Binary-Phase Fourier Gratings for Nonuniform Array Generation

    NASA Technical Reports Server (NTRS)

    Keys, Andrew S.; Crow, Robert W.; Ashley, Paul R.; Nelson, Tom R., Jr.; Parker, Jack H.; Beecher, Elizabeth A.

    2004-01-01

    This effort describes the fabrication and testing of binary-phase Fourier gratings designed to generate an incoherent array of output source points with nonuniform user-defined intensities, symmetric about the zeroth order. Like Dammann fanout gratings, these binary-phase Fourier gratings employ only two phase levels to generate a defined output array. Unlike Dammann fanout gratings, these gratings generate an array of nonuniform, user-defined intensities when projected into the far-field regime. The paper describes the process of design, fabrication, and testing for two different version of the binary-phase grating; one designed for a 12 micron wavelength, referred to as the Long-Wavelength Infrared (LWIR) grating, and one designed for a 5 micron wavelength, referred to as the Mid-Wavelength Infrared Grating (MWIR).

  6. Phase-space distributions in quasi-polar coordinates and the fractional Fourier transform.

    PubMed

    Alieva, T; Bastiaans, M J

    2000-12-01

    The ambiguity function and Cohen's class of bilinear phase-space distributions are represented in a quasipolar coordinate system instead of in a Cartesian system. Relationships between these distributions and the fractional Fourier transform are derived; in particular, derivatives of the ambiguity function are related to moments of the fractional power spectra. A simplification is achieved for the description of underspread signals, for optical beam characterization, and for the generation of signal-adaptive phase-space distributions. PMID:11140493

  7. Alpha-rooting method of color image enhancement by discrete quaternion Fourier transform

    NASA Astrophysics Data System (ADS)

    Grigoryan, Artyom M.; Agaian, Sos S.

    2014-02-01

    This paper presents a novel method for color image enhancement based on the discrete quaternion Fourier transform. We choose the quaternion Fourier transform, because it well-suited for color image processing applications, it processes all 3 color components (R,G,B) simultaneously, it capture the inherent correlation between the components, it does not generate color artifacts or blending , finally it does not need an additional color restoration process. Also we introduce a new CEME measure to evaluate the quality of the enhanced color images. Preliminary results show that the ?-rooting based on the quaternion Fourier transform enhancement method out-performs other enhancement methods such as the Fourier transform based ?-rooting algorithm and the Multi scale Retinex. On top, the new method not only provides true color fidelity for poor quality images but also averages the color components to gray value for balancing colors. It can be used to enhance edge information and sharp features in images, as well as for enhancing even low contrast images. The proposed algorithms are simple to apply and design, which makes them very practical in image enhancement.

  8. Analysis of Generalization of a Series of Images by Superimposed Fourier Holograms

    NASA Astrophysics Data System (ADS)

    Pavlov, A. V.

    2016-02-01

    The problem of recognition of the common fragments in a series of images in the absence of a priori criteria relating any one fragment to the common fragments, apart from the frequency of its appearance, is considered with application to recording of superimposed Fourier holograms with spatially modulated reference images. An analysis of the dependence of the variance of the reconstructed images on the number of superimposed holograms and the characteristics of the recorded images is given. It is shown that the problem can be solved for correlated reference images. Theoretical conclusions are confirmed by numerical modeling for presentation images by realizations of a stationary random process.

  9. Extreme Ultraviolet Phase Contrast Imaging

    SciTech Connect

    Denbeaux, Gregory; Garg, Rashi; Aquila, Andy; Barty, Anton; Goldberg, Kenneth; Gullikson, Eric; Liu, Yanwei; Wood, Obert

    2005-11-01

    The conclusions of this report are: (1) zone plate microscopy provides high resolution imaging of EUV masks; (2) using phase plates in the back focal plane of the objective lens can provide contrast mechanisms for measurement of the phase shift from defects on the mask; (3) the first high resolution EUV Zernike phase contrast images have been acquired; and (4) future work will include phase contrast mode in reflection from an EUV mask to directly measure the reflectivity and phase shift from defects.

  10. Improvement of quality of optical reconstruction of digital Fourier holograms displayed on phase-only SLM by its digital preprocessing

    NASA Astrophysics Data System (ADS)

    Cheremkhin, Pavel A.; Evtikhiev, Nikolay N.; Krasnov, Vitaly V.; Porshneva, Liudmila A.; Rodin, Vladislav G.; Starikov, Sergey N.

    2014-10-01

    Digital holography is popular tool for research and practical applications in various fields of science and technology. Most widespread method of optical reconstruction implements digital hologram display on spatial light modulators (SLM). Optical reconstruction of digital holograms is used for remote display of static and dynamic 2D and 3D scenes, in optical information processing, metrology, interferometry, microscopy, etc. Holograms recorded with digital cameras are amplitude type. Therefore quality of its optical reconstruction with phase SLM is worse compared to amplitude SLM. However application of phase SLM can provide higher diffraction efficiency. To improve quality of optical reconstruction with phase SLM, method of SLM phase modulation depth reduction at digital hologram display is proposed. To our knowledge, this method was applied only in analog holography. Also two other methods of quality improvement are considered: hologram to kinoform conversion and holograms multiplexing. Numerical experiments on modelling of digital Fourier holograms recording and their optical reconstruction by phase SLM were performed. Method of SLM phase modulation depth reduction at digital holograms display was proposed and tested. SLM phase modulation depth ranged from 0 to 2π. Quantity of hologram phase levels equal to 256 corresponds to 2π phase modulation depth. To keep SLM settings while changing phase modulation depth hologram phase distribution was renormalized instead. Dependencies of reconstruction quality on hologram phase modulation depth were obtained. Best quality is achieved at 0.27π÷0.31π phase modulation depth. To reduce speckle noise, hologram multiplexing can be applied. Modeling of multiplex holograms optical reconstruction was conducted. Speckle noise reduction was achieved. For improvement of digital hologram optical reconstruction quality and diffraction efficiency hologram to kinoform conversion can be used. Firstly numerically reconstructed image of object was obtained. Then this image was used for kinoform synthesis. Diffraction efficiency was increased by 6.4 times in comparison with hologram reconstruction.

  11. Three-dimensional full-range complex Fourier domain optical coherence tomography for in-vivo volumetric imaging of human skin

    NASA Astrophysics Data System (ADS)

    Nan, Nan; Bu, Peng; Guo, Xin; Wang, Xiangzhao

    2011-11-01

    A three dimensional full-range complex Fourier domain optical coherence tomography (complex FDOCT) system based on sinusoidal phase-modulating method is proposed. With the system, the range of imaging depth is doubled and the sensitivity degradation with the lateral scan distance is avoided. Fourier analysis of B-scan data along lateral scan distance is used for reconstructing the complex spectral interferograms. The B-scan based Fourier method improves the system tolerance of sample movement and makes data processing less time consuming. In vivo volumetric imaging of human skin with the proposed full-range FDOCT system is demonstrated. The mirror image rejection ratio is about 30 dB. The stratum corneum, the epidermis and the upper dermis of skin can be clearly identified in the reconstructed three dimensional FDOCT images.

  12. Three-dimensional full-range complex Fourier domain optical coherence tomography for in-vivo volumetric imaging of human skin

    NASA Astrophysics Data System (ADS)

    Nan, Nan; Bu, Peng; Guo, Xin; Wang, Xiangzhao

    2012-03-01

    A three dimensional full-range complex Fourier domain optical coherence tomography (complex FDOCT) system based on sinusoidal phase-modulating method is proposed. With the system, the range of imaging depth is doubled and the sensitivity degradation with the lateral scan distance is avoided. Fourier analysis of B-scan data along lateral scan distance is used for reconstructing the complex spectral interferograms. The B-scan based Fourier method improves the system tolerance of sample movement and makes data processing less time consuming. In vivo volumetric imaging of human skin with the proposed full-range FDOCT system is demonstrated. The mirror image rejection ratio is about 30 dB. The stratum corneum, the epidermis and the upper dermis of skin can be clearly identified in the reconstructed three dimensional FDOCT images.

  13. Fourier magnetic imaging with nanoscale resolution and compressed sensing speed-up using electronic spins in diamond

    NASA Astrophysics Data System (ADS)

    Arai, K.; Belthangady, C.; Zhang, H.; Bar-Gill, N.; Devience, S. J.; Cappellaro, P.; Yacoby, A.; Walsworth, R. L.

    2015-10-01

    Optically detected magnetic resonance using nitrogen-vacancy (NV) colour centres in diamond is a leading modality for nanoscale magnetic field imaging, as it provides single electron spin sensitivity, three-dimensional resolution better than 1 nm (ref. 5) and applicability to a wide range of physical and biological samples under ambient conditions. To date, however, NV-diamond magnetic imaging has been performed using ‘real-space’ techniques, which are either limited by optical diffraction to ˜250 nm resolution or require slow, point-by-point scanning for nanoscale resolution, for example, using an atomic force microscope, magnetic tip, or super-resolution optical imaging. Here, we introduce an alternative technique of Fourier magnetic imaging using NV-diamond. In analogy with conventional magnetic resonance imaging (MRI), we employ pulsed magnetic field gradients to phase-encode spatial information on NV electronic spins in wavenumber or ‘k-space’ followed by a fast Fourier transform to yield real-space images with nanoscale resolution, wide field of view and compressed sensing speed-up.

  14. Fourier magnetic imaging with nanoscale resolution and compressed sensing speed-up using electronic spins in diamond.

    PubMed

    Arai, K; Belthangady, C; Zhang, H; Bar-Gill, N; DeVience, S J; Cappellaro, P; Yacoby, A; Walsworth, R L

    2015-10-01

    Optically detected magnetic resonance using nitrogen-vacancy (NV) colour centres in diamond is a leading modality for nanoscale magnetic field imaging, as it provides single electron spin sensitivity, three-dimensional resolution better than 1 nm (ref. 5) and applicability to a wide range of physical and biological samples under ambient conditions. To date, however, NV-diamond magnetic imaging has been performed using 'real-space' techniques, which are either limited by optical diffraction to ∼250 nm resolution or require slow, point-by-point scanning for nanoscale resolution, for example, using an atomic force microscope, magnetic tip, or super-resolution optical imaging. Here, we introduce an alternative technique of Fourier magnetic imaging using NV-diamond. In analogy with conventional magnetic resonance imaging (MRI), we employ pulsed magnetic field gradients to phase-encode spatial information on NV electronic spins in wavenumber or 'k-space' followed by a fast Fourier transform to yield real-space images with nanoscale resolution, wide field of view and compressed sensing speed-up. PMID:26258549

  15. Differential phase contrast tomosynthesis imaging

    NASA Astrophysics Data System (ADS)

    Li, Ke; Bevins, Nicholas; Zambelli, Joseph; Chen, Guang-Hong

    2012-03-01

    The development of differential phase contrast imaging using conventional x-ray tubes has spurred great interest in the medical imaging community. It has been shown to provide higher contrast than absorption imaging in some cases, and in this work we translate these advantages to tomosynthesis imaging. A general framework for reconstruction of images from differential phase contrast projection data has been proposed and implemented using data from a grating-based x-ray phase contrast tomosynthesis system. Reconstructed tomosynthesis images from differential phase contrast data are shown, using both a direct backprojection (BP) technique and a filtered backprojection (FBP) reconstruction method. From the results it is seen that phase contrast tomosynthesis can separate superimposed phase objects while providing complementary information to absorption tomosynthesis.

  16. Spectral multiplexing and coherent-state decomposition in Fourier ptychographic imaging

    PubMed Central

    Dong, Siyuan; Shiradkar, Radhika; Nanda, Pariksheet; Zheng, Guoan

    2014-01-01

    Information multiplexing is important for biomedical imaging and chemical sensing. In this paper, we report a microscopy imaging technique, termed state-multiplexed Fourier ptychography (FP), for information multiplexing and coherent-state decomposition. Similar to a typical Fourier ptychographic setting, we use an array of light sources to illuminate the sample from different incident angles and acquire corresponding low-resolution images using a monochromatic camera. In the reported technique, however, multiple light sources are lit up simultaneously for information multiplexing, and the acquired images thus represent incoherent summations of the sample transmission profiles corresponding to different coherent states. We show that, by using the state-multiplexed FP recovery routine, we can decompose the incoherent mixture of the FP acquisitions to recover a high-resolution sample image. We also show that, color-multiplexed imaging can be performed by simultaneously turning on R/G/B LEDs for data acquisition. The reported technique may provide a solution for handling the partially coherent effect of light sources used in Fourier ptychographic imaging platforms. It can also be used to replace spectral filter, gratings or other optical components for spectral multiplexing and demultiplexing. With the availability of cost-effective broadband LEDs, the reported technique may open up exciting opportunities for computational multispectral imaging. PMID:24940538

  17. Spectral multiplexing and coherent-state decomposition in Fourier ptychographic imaging.

    PubMed

    Dong, Siyuan; Shiradkar, Radhika; Nanda, Pariksheet; Zheng, Guoan

    2014-06-01

    Information multiplexing is important for biomedical imaging and chemical sensing. In this paper, we report a microscopy imaging technique, termed state-multiplexed Fourier ptychography (FP), for information multiplexing and coherent-state decomposition. Similar to a typical Fourier ptychographic setting, we use an array of light sources to illuminate the sample from different incident angles and acquire corresponding low-resolution images using a monochromatic camera. In the reported technique, however, multiple light sources are lit up simultaneously for information multiplexing, and the acquired images thus represent incoherent summations of the sample transmission profiles corresponding to different coherent states. We show that, by using the state-multiplexed FP recovery routine, we can decompose the incoherent mixture of the FP acquisitions to recover a high-resolution sample image. We also show that, color-multiplexed imaging can be performed by simultaneously turning on R/G/B LEDs for data acquisition. The reported technique may provide a solution for handling the partially coherent effect of light sources used in Fourier ptychographic imaging platforms. It can also be used to replace spectral filter, gratings or other optical components for spectral multiplexing and demultiplexing. With the availability of cost-effective broadband LEDs, the reported technique may open up exciting opportunities for computational multispectral imaging. PMID:24940538

  18. Full-Stokes Fourier-transform imaging spectropolarimeter using a time-division polarization modulator.

    PubMed

    Meng, Xin; Li, Jianxin; Song, Huaqing; Zhu, Rihong

    2014-08-20

    A Fourier-transform imaging spectropolarimeter is presented and demonstrated. It is composed of a time-division polarization modulator and a high radiation throughput Fourier-transform spectrometer. Four polarization states of the input light are generated by rotating the retarder. Then, the polarized light enters the Fourier-transform spectrometer to create four sets of interferometric images, where we can recover four polarization spectra and calculate the full-Stokes vector in various wavenumber frequency. The method has good performance to resist instrument noise and has the advantage of high spatial resolution. The laboratory setup is described and the noise source is analyzed. Two proven experiments have been carried out in visible light. PMID:25321096

  19. Fourier spectrum and phases for a signal in a finite interval

    NASA Astrophysics Data System (ADS)

    Belmont, Gérard; Dorville, Nicolas; Sahraoui, Fouad; Rezeau, Laurence

    2015-04-01

    When investigating the physics of turbulent media, as the solar wind or the magnetosheath plasmas, obtaining accurate Fourier spectra and phases is a crucial issue. For the different fields, the spectra allow in particular verifying whether one or several power laws can be determined in different frequency ranges. Accurate phases are necessary as well for all the "higher order statistics" studies in Fourier space, the coherence ones and for the polarization studies. Unfortunately, the Fourier analysis is not unique for a finite time interval of duration T: the frequencies lower than 1/T have a large influence on the result, which can hardly be controlled. This unknown "trend" has in particular the effect of introducing jumps at the edges of the interval, for the function under study itself, as well as for all its derivatives. The Fourier transform obtained directly by FFT (Fast Fourier Transform) is generally much influenced by these effects and cannot be used without care for wide band signals. The interference between the jumps and the signal itself provide in particular characteristic "hairs" on the spectrum, which are clearly visible on it with df≈1/T. These fluctuations are usually eliminated by smoothing the spectrum, or by averaging several successive spectra. Nevertheless, such treatments introduce uncertainties on the spectral laws (the phases being anyway completely lost). Windowing is also a method currently used to suppress or decrease the jumps, but it modifies the signal (the windowed trend has a spectrum, which is convolved with the searched one) and the phases are generally much altered. Here, we present a new data processing technique to circumvent these difficulties. It takes advantage of the fact that the signal is generally not unknown out of the interval under study: the complete signal is tapered to this interval of interest thanks to a new window function, sharp but not square. This window function is chosen such that the spectrum obtained can be deconvolved almost exactly, through a minimization procedure based on the -weak- hypothesis that it is smooth at the scale of a few successive spectral points. Then, a later step allows reconstructing the phases. Tests with synthetic data and first applications to Cluster data are presented, which demonstrate the capability of the method to better estimate the Fourier spectra.

  20. The keyed optical Hash function based on cascaded phase-truncated Fourier transforms

    NASA Astrophysics Data System (ADS)

    He, Wenqi; Peng, Xiang; Qin, Wan; Meng, Xiangfeng

    2010-06-01

    An approach for constructing keyed optical Hash function (KOHF) is proposed, which is based on cascaded phase-truncated Fourier transforms (CPTFTs). The KOHF is created from a two-step one-way encryption process with a secret key imbedded. The non-linearity and one-way functionality is introduced by cascaded optical Fourier transforms with the phase-truncation operations, which could be implemented either digitally or optically. Once two 64-bit keyed Hash values are obtained in the two-step one-way encryption processes, respectively, they are then combined to form a final 128-bit keyed Hash value, which can also be regarded as a message authentication code (MAC). Moreover, the avalanche effect is also evaluated to show the performance of constructed KOHF with a set of numerical experiments.

  1. Optical image encryption based on two-dimensional N-parameter fractional Fourier transform

    NASA Astrophysics Data System (ADS)

    Zhang, Haiying; Ran, Qiwen; Xiao, Yu; Ma, Jing; Tan, Liying; Zhang, Jin; Wei, Deyun

    2009-07-01

    In this paper, the weighted fractional Fourier transform with dilation parameter (N-PFRFT) is proposed as the weighted combination of the first four integer-order ordinary Fourier transforms. This N-PFRFT is an extension of four-item weighted fractional Fourier transform (N-PFRFT) defined by Shih[1] and it owns four free parameters in the weight coefficients besides the order of the fractional Fourier transform. A novel image encryption algorithm is presented by the N-PFRFT.The method owns more secret keys than the encryption methods operated by other fractional Fourier transforms without any increase of the computational complexity. On the other hand, the image still can't be decrypted correctly even though the order of FRFT which is treated as a secret key is known. So do the four free parameters. Therefore, both the order parameter and the vector parameter can be chosen in the real domain to improve the security of the encryption method. Digital simulations are presented to verify the more validity and efficiency of the algorithm.

  2. Instrumental phase-based method for Fourier transform spectrometer measurements processing

    SciTech Connect

    Saggin, Bortolino; Scaccabarozzi, Diego; Tarabini, Marco

    2011-04-20

    Phase correction is a critical procedure for most space-borne Fourier transform spectrometers (FTSs) whose accuracy (owing to often poor signal-to-noise ratio, SNR) can be jeopardized from many uncontrollable environmental conditions. This work considers the phase correction in an FTS working under significant temperature change during the measurement and affected by mechanical disturbances. The implemented method is based on the identification of an instrumental phase that is dependent on the interferometer temperature and on the extraction of a linear phase component through a least-squares approach. The use of an instrumental phase parameterized with the interferometer temperature eases the determination of the linear phase that can be extracted using only a narrow spectral region selected to be immune from disturbances. The procedure, in this way, is made robust against phase errors arising from instrumental effects, a key feature to reduce the disturbances through spectra averaging. The method was specifically developed for the Mars IR Mapper spectrometer, that was designed for operation onboard a rover on the Mars surface; the validation was performed using ground and in-flight measurements of the Fourier transform IR spectrometer planetary Fourier spectrometer, onboard the MarsExpress mission. The symmetrization has been exploited also for the spectra calibration, highlighting the issues deriving from the cases of relevant beamsplitter emission. The applicability of this procedure to other instruments is conditional to the presence in the spectra of at least one spectral region with a large SNR along with a negligible (or known) beamsplitter emission. For the PFS instrument, the processing of data with relevant beamsplitter emission has been performed exploiting the absorption carbon dioxide bands present in Martian spectra.

  3. Gaseous effluent monitoring and identification using an imaging Fourier transform spectrometer

    SciTech Connect

    Carter, M.R.; Bennett, C.L.; Fields, D.J.; Hernandez, J.

    1993-10-01

    We are developing an imaging Fourier transform spectrometer for chemical effluent monitoring. The system consists of a 2-D infrared imaging array in the focal plane of a Michelson interferometer. Individual images are coordinated with the positioning of a moving mirror in the Michelson interferometer. A three dimensional data cube with two spatial dimensions and one interferogram dimension is then Fourier transformed to produce a hyperspectral data cube with one spectral dimension and two spatial dimensions. The spectral range of the instrument is determined by the choice of optical components and the spectral range of the focal plane array. Measurements in the near UV, visible, near IR, and mid-IR ranges are possible with the existing instrument. Gaseous effluent monitoring and identification measurements will be primarily in the ``fingerprint`` region of the spectrum, ({lambda} = 8 to 12 {mu}m). Initial measurements of effluent using this imaging interferometer in the mid-IR will be presented.

  4. Two-dimensional Kerr-Fourier imaging of translucent phantoms in thick turbid media

    NASA Astrophysics Data System (ADS)

    Liang, X.; Wang, L.; Ho, P. P.; Alfano, R. R.

    1995-06-01

    Translucent scattering phantoms hidden inside a 5.5-cm-thick Intralipid solution were imaged as a function of phantom scattering coefficients by the use of a picosecond time-and space-gated Kerr-Fourier imaging system. A 2-mm-thick translucent phantom with a 0.1% concentration (scattering coefficient) difference from the 55-mm-thick surrounding scattering host can be distinguished at a signal level of approximately 10-10 of the incidence illumination intensity.

  5. Single-channel color image encryption based on iterative fractional Fourier transform and chaos

    NASA Astrophysics Data System (ADS)

    Sui, Liansheng; Gao, Bo

    2013-06-01

    A single-channel color image encryption is proposed based on iterative fractional Fourier transform and two-coupled logistic map. Firstly, a gray scale image is constituted with three channels of the color image, and permuted by a sequence of chaotic pairs which is generated by two-coupled logistic map. Firstly, the permutation image is decomposed into three components again. Secondly, the first two components are encrypted into a single one based on iterative fractional Fourier transform. Similarly, the interim image and third component are encrypted into the final gray scale ciphertext with stationary white noise distribution, which has camouflage property to some extent. In the process of encryption and description, chaotic permutation makes the resulting image nonlinear and disorder both in spatial domain and frequency domain, and the proposed iterative fractional Fourier transform algorithm has faster convergent speed. Additionally, the encryption scheme enlarges the key space of the cryptosystem. Simulation results and security analysis verify the feasibility and effectiveness of this method.

  6. Optical coherence tomography for imaging of subpleural alveolar structure using a Fourier domain mode locked laser

    NASA Astrophysics Data System (ADS)

    Kirsten, Lars; Walther, Julia; Cimalla, Peter; Gaertner, Maria; Meissner, Sven; Koch, Edmund

    2011-06-01

    Optical coherence tomography (OCT) is a noninvasive imaging modality generating cross sectional and volumetric images of translucent samples. In Fourier domain OCT (FD OCT), the depth profile is calculated by a fast Fourier transformation of the interference spectrum, providing speed and SNR advantage and thus making FD OCT well suitable in biomedical applications. The interference spectrum can be acquired spectrally resolved in spectral domain OCT or time-resolved in optical frequency domain imaging (OFDI). Since OCT images still suffer from motion artifacts, especially under in vivo conditions, increased depth scan rates are required. Therefor, the principle of Fourier domain mode locking has been presented by R. Huber et al. circumventing the speed limitations of conventional FD OCT systems. In FDML lasers, a long single mode fiber is inserted in the ring resonator of the laser resulting in an optical round trip time of a few microseconds. Sweeping the wavelength synchronously by a tunable Fabry-Perot filter can provide wavelength sweeps with repetition rates up to a few MHz used for OFDI. Imaging of subpleural lung tissue for investigation of lung dynamics and its elastic properties is a further biomedical application demanding high-speed OCT imaging techniques. For the first time, the visualization of subpleural alveolar structures of a rabbit lung is presented by the use of an FDML-based OCT system enabling repetition rates of 49.5 kHz and 122.6 kHz, respectively.

  7. Application of Fourier descriptors and fuzzy logic to classification of radar subsurface images

    NASA Astrophysics Data System (ADS)

    Parsiani, Hamed; Tolstoy, Leonid

    2004-02-01

    This paper presents an application of Fourier Descriptors and Fuzzy Logic for the recognition of archeological artifacts in Ground Penetrating Radar (GPR) images of a surveyed site. 2-D GPR survey images of a site are made available by NASA-SSC center. The buried artifacts in these images appear in the form of hyperbolas which are the results of radar backscatter from the artifacts. The Fourier Descriptors of an image are applied as inputs to a Fuzzy C-Mean Classifier (FCMC). The FCMC algorithm has to recognize different types of shapes, in order to separate hyperbola-like shapes from non-hyperbola shapes in the sub-surface images. The procedure consisted of removing background noise using a suitable threshold filter, locating the separate shapes in the image using N8(p) connectivity algorithm, calculating a short sequence of Fourier Descriptors (FD) of each isolated shape, and obtaining an unsupervised classification by applying Fuzzy C-Mean clustering algorithm to the FD sequences. The classes obtained depend upon the requirements of the user, namely, two classes of hyperbola/no-hyperbola objects, or several classes from symmetric hyperbolas to total rejects could be obtained. The results consisting of recognized hyperbolas indicate the presence of buried artifacts. Also, our previous results of supervised FD-Neural Network (FD-NNC) published in the proceedings of SPIE 2002 are compared with unsupervised FD-FCMC. The compared results in terms of the quality of classification are presented in this work.

  8. Extracting and compensating dispersion mismatch in ultrahigh-resolution Fourier domain OCT imaging of the retina

    PubMed Central

    Choi, WooJhon; Baumann, Bernhard; Swanson, Eric A.; Fujimoto, James G.

    2012-01-01

    We present a numerical approach to extract the dispersion mismatch in ultrahigh-resolution Fourier domain optical coherence tomography (OCT) imaging of the retina. The method draws upon an analogy with a Shack-Hartmann wavefront sensor. By exploiting mathematical similarities between the expressions for aberration in optical imaging and dispersion mismatch in spectral / Fourier domain OCT, Shack-Hartmann principles can be extended from the two-dimensional paraxial wavevector space (or the x-y plane in the spatial domain) to the one-dimensional wavenumber space (or the z-axis in the spatial domain). For OCT imaging of the retina, different retinal layers, such as the retinal nerve fiber layer (RNFL), the photoreceptor inner and outer segment junction (IS/OS), or all the retinal layers near the retinal pigment epithelium (RPE) can be used as point source beacons in the axial direction, analogous to point source beacons used in conventional two-dimensional Shack-Hartman wavefront sensors for aberration characterization. Subtleties regarding speckle phenomena in optical imaging, which affect the Shack-Hartmann wavefront sensor used in adaptive optics, also occur analogously in this application. Using this approach and carefully suppressing speckle, the dispersion mismatch in spectral / Fourier domain OCT retinal imaging can be successfully extracted numerically and used for numerical dispersion compensation to generate sharper, ultrahigh-resolution OCT images. PMID:23187353

  9. FPGA-based phase control of acousto-optic modulator Fourier synthesis system through gradient descent phase-locking algorithm.

    PubMed

    Underwood, Kenneth J; Jones, Andrew M; Gopinath, Juliet T

    2015-06-20

    We present a new application of the stochastic parallel gradient descent (SPGD) algorithm to fast active phase control in a Fourier synthesis system. Pulses (4.9 ns) with an 80 MHz repetition rate are generated by feedback from a single phase-sensitive metric. Phase control is applied via fast current modulation of a tapered amplifier using an SPGD algorithm realized on a field-programmable gate array (FPGA). The waveforms are maintained by constant active feedback from the FPGA. We also discuss the extension of this technique to many more semiconductor laser emitters in a diode laser array. PMID:26193004

  10. Crystallographic phase retrieval through image processing under constraints

    NASA Astrophysics Data System (ADS)

    Zhang, Kam Y.

    1993-11-01

    The crystallographic image processing techniques of Sayre's equation, molecular averaging, solvent flattening and histogram matching are combined in an integrated procedure for macromolecular phase retrieval. It employs the constraints of the local shape of electron density, equal molecules, solvent flatness and correct electron density distribution. These constraints on electron density image are satisfied simultaneously by solving a system of non- linear equations using fast Fourier transform. The electron density image is further filtered under the constraint of observed diffraction amplitudes. The effect of each constraint on phase retrieval is examined. The constraints are found to work synergistically in phase retrieval. Test results on 2Zn insulin are presented.

  11. Fourier-domain mode delay measurement for multimode fibers using phase detection

    NASA Astrophysics Data System (ADS)

    Kim, Chan-Young; Ahn, Tae-Jung

    2015-06-01

    We have proposed a powerful method based on a phase detection reflectometric technique to solve the difficulty of the small signal discrimination in the amplitude-detection method for differential modal delay measurement of multimode optical fibers (MMFs). The phase is radically shifted to π at the time delay positions among the excited modes even when the amplitudes of the peaks cannot be distinguished with the noise level. The modal dispersion of the MMF under test can be simply determined by choosing the time delay in the last phase shift in the Fourier domain. In addition, we confirmed that the phase-sensitive interferometric measurement does not need to scramble the excited modes in the fiber. We subsequently conclude that a portable modal dispersion or mode analysis equipment can be developed by using the phase-detection intermodal interferometric technique proposed here.

  12. Fourier spectrum and phases for a signal in a finite interval

    NASA Astrophysics Data System (ADS)

    Dorville, N.; Belmont, G.; Sahraoui, F.; Rezeau, L.

    2014-12-01

    When investigating the physics of turbulent media, as the solar wind or the magnetosheath plasmas, obtaining accurate Fourier spectra and phases is a crucial issue. For the different fields, the spectra allow in particular verifying whether one or several power laws can be determined in different frequency ranges. Accurate phases are necessary as well for all the "higher order statistics" studies in Fourier space, the coherence ones and for the polarization studies. Unfortunately, the Fourier analysis is not unique for a finite time interval of duration T: the frequencies lower than 1/T have a large influence on the result, which can hardly be controlled. This unknown "trend" has in particular the effect of superposing jumps at the edges of the interval, for the function under study itself, as well as for all its derivatives. The Fourier transform obtained directly by FFT (Fast Fourier Transform) is generally much influenced by these effects and cannot be used without care for wide band signals. The interferences between the jumps and the signal itself also provide "hairs" on the spectrum, which are clearly visible fluctuations with df≈1/T. These fluctuations are usually eliminated by smoothing the spectrum, or by averaging several successive spectra. Nevertheless, such smoothing introduces uncertainties on the spectral laws and it makes the phases lost. Windowing is also a method currently used to suppress the jumps, but it modifies the signal (the windowed trend has a spectrum, which is convolved with the searched one) and the phases are also lost to a large extent. Here, we present a new data processing technique to circumvent these difficulties. It takes advantage of the fact that the signal is generally not unknown out of the interval under study: the complete signal is tapered to this interval of interest thanks to a new kind of window, sharp but not square. This kind of window is such that the spectrum obtained can then be deconvolved almost exactly, through a minimization procedure based on the -weak- hypothesis that it is smooth at the scale of a few successive spectral points. Then, a later step allows reconstructing the phases. Tests with synthetic data are presented, that demonstrate the efficiency of the method, and first results from Cluster data are also shown.

  13. Parameter estimation of optical fringes with quadratic phase using the fractional Fourier transform

    NASA Astrophysics Data System (ADS)

    Lu, Ming-Feng; Zhang, Feng; Tao, Ran; Ni, Guo-Qiang; Bai, Ting-Zhu; Yang, Wen-Ming

    2015-11-01

    Optical fringes with a quadratic phase are often encountered in optical metrology. Parameter estimation of such fringes plays an important role in interferometric measurements. A novel method is proposed for accurate and direct parameter estimation using the fractional Fourier transform (FRFT), even in the presence of noise and obstacles. We take Newton's rings fringe patterns and electronic speckle pattern interferometry (ESPI) interferograms as classic examples of optical fringes that have a quadratic phase and present simulation and experimental results demonstrating the performance of the proposed method.

  14. Novel Algorithm for Polar and Spherical Fourier Analysis on Two and Three Dimensional Images

    NASA Astrophysics Data System (ADS)

    Yang, Zhuo; Kamata, Sei-Ichiro

    Polar and Spherical Fourier analysis can be used to extract rotation invariant features for image retrieval and pattern recognition tasks. They are demonstrated to show superiorities comparing with other methods on describing rotation invariant features of two and three dimensional images. Based on mathematical properties of trigonometric functions and associated Legendre polynomials, fast algorithms are proposed for multimedia applications like real time systems and large multimedia databases in order to increase the computation speed. The symmetric points are computed simultaneously. Inspired by relative prime number theory, systematic analysis are given in this paper. Novel algorithm is deduced that provide even faster speed. Proposed method are 9-15% faster than previous work. The experimental results on two and three dimensional images are given to illustrate the effectiveness of the proposed method. Multimedia signal processing applications that need real time polar and spherical Fourier analysis can be benefit from this work.

  15. [The meteorological satellite spectral image registration based on Fourier-Mellin transform].

    PubMed

    Wang, Liang; Liu, Rong; Zhang, Li; Duan, Fu-Qing; Lü, Ke

    2013-03-01

    The meteorological satellite spectral image is an effective tool for researches on meteorological science and environmental remote sensing science. Image registration is the basis for the application of the meteorological satellite spectral image data. In order to realize the registration of the satellite image and the template image, a new registration method based on the Fourier-Mellin transform is presented in this paper. Firstly, we use the global coastline vector map data to build a landmark template, which is a reference for the meteorological satellite spectral image registration. Secondly, we choose infrared sub-image of no cloud according to the cloud channel data, and extract the edges of the infrared image by Sobel operator. Finally, the affine transform model parameters between the landmark template and the satellite image are determined by the Fourier-Mellin transform, and thus the registration is realized. The proposed method is based on the curve matching in essence. It needs no feature point extraction, and can greatly simplify the process of registration. The experimental results using the infrared spectral data of the FY-2D meteorological satellite show that the method is robust and can reach a high speed and high accuracy. PMID:23705469

  16. A data-dependent Fourier filter based on image segmentation for random seismic noise attenuation

    NASA Astrophysics Data System (ADS)

    Zhou, JiaXiong; Lu, Wenkai; He, Jianwei; Liu, Bing; Ren, Tin

    2015-03-01

    In this paper, we propose a data-dependent Fourier filter (DDFF) based on image segmentation for random seismic noise attenuation. In the proposed method, the original seismic data is divided into some overlapped small blocks. For each block, a local Fourier filter is designed automatically in two steps. At first, a binary mask is obtained by segmenting the Fourier amplitude spectra (FAS) of this block. The histogram of the FAS is used to get the threshold for the FAS segmentation. Secondly, an average filter is applied on the binary mask to get the tapered Fourier filter. In the proposed method, the DDFFs for all blocks are compact and time-space variant. After all blocks are processed, they are merged together to form the filtered result. We illustrate our method by a 2D synthetic seismic data, and give a comparison with the coherent event extraction method in Fourier domain. At last, a real 3D seismic data example demonstrates that the proposed method obtains some promising results.

  17. Fourier-based linear systems description of free-breathing pulmonary magnetic resonance imaging

    NASA Astrophysics Data System (ADS)

    Capaldi, D. P. I.; Svenningsen, S.; Cunningham, I. A.; Parraga, G.

    2015-03-01

    Fourier-decomposition of free-breathing pulmonary magnetic resonance imaging (FDMRI) was recently piloted as a way to provide rapid quantitative pulmonary maps of ventilation and perfusion without the use of exogenous contrast agents. This method exploits fast pulmonary MRI acquisition of free-breathing proton (1H) pulmonary images and non-rigid registration to compensate for changes in position and shape of the thorax associated with breathing. In this way, ventilation imaging using conventional MRI systems can be undertaken but there has been no systematic evaluation of fundamental image quality measurements based on linear systems theory. We investigated the performance of free-breathing pulmonary ventilation imaging using a Fourier-based linear system description of each operation required to generate FDMRI ventilation maps. Twelve subjects with chronic obstructive pulmonary disease (COPD) or bronchiectasis underwent pulmonary function tests and MRI. Non-rigid registration was used to co-register the temporal series of pulmonary images. Pulmonary voxel intensities were aligned along a time axis and discrete Fourier transforms were performed on the periodic signal intensity pattern to generate frequency spectra. We determined the signal-to-noise ratio (SNR) of the FDMRI ventilation maps using a conventional approach (SNRC) and using the Fourier-based description (SNRF). Mean SNR was 4.7 ± 1.3 for subjects with bronchiectasis and 3.4 ± 1.8, for COPD subjects (p>.05). SNRF was significantly different than SNRC (p<.01). SNRF was approximately 50% of SNRC suggesting that the linear system model well-estimates the current approach.

  18. Digital watermarking algorithm research of color images based on quaternion Fourier transform

    NASA Astrophysics Data System (ADS)

    An, Mali; Wang, Weijiang; Zhao, Zhen

    2013-10-01

    A watermarking algorithm of color images based on the quaternion Fourier Transform (QFFT) and improved quantization index algorithm (QIM) is proposed in this paper. The original image is transformed by QFFT, the watermark image is processed by compression and quantization coding, and then the processed watermark image is embedded into the components of the transformed original image. It achieves embedding and blind extraction of the watermark image. The experimental results show that the watermarking algorithm based on the improved QIM algorithm with distortion compensation achieves a good tradeoff between invisibility and robustness, and better robustness for the attacks of Gaussian noises, salt and pepper noises, JPEG compression, cropping, filtering and image enhancement than the traditional QIM algorithm.

  19. High-definition Fourier transform infrared spectroscopic imaging of breast tissue

    NASA Astrophysics Data System (ADS)

    Leslie, L. Suzanne; Kadjacsy-Balla, Andre; Bhargava, Rohit

    2015-03-01

    Breast cancer diagnosis relies on staining serial sections of a biopsy in a process that can be time intensive and costly. Fourier transform infrared imaging (FT-IR) is a non-destructive, label-free chemical imaging technique that uses the vibrational structure of the biological molecules of the sample to provide contrast for images at any absorption peak in the mid-infrared. The full potential of spectroscopic imaging has been limited by the spatial resolution provided by most commercial instruments. By increasing the magnification and numerical aperture of the microscope, image pixel sizes on the order of 1.1 micron can be achieved, allowing HD FT-IR spectroscopic imaging to provide high quality images that could aid in histopathology, diagnosis, and studies of breast cancer progression.

  20. Fourier transform-based absolute phase interrogation algorithm for Sagnac interferometer-based PMF sensors

    NASA Astrophysics Data System (ADS)

    Chen, Yuxuan; Yang, Yuanhong; Liu, Shuo; Yang, Mingwei; Jin, Wei

    2015-09-01

    A high resolution and absolute phase interrogation algorithm for Sagnac interferometer based polarization maintaining fiber (PMF) sensor is proposed. Taking wavenumber instead of wavelength as the function variable, the output spectrum will be a standard cosine spectrum function. After Fourier transform, the frequency and relative phase of this spectrum function can be obtained and the precise absolute phase due to optical path difference between the two polarization modes in sensing PMF can be determined. A typical Sagnac interferometer based PMF temperature sensor was built and the absolute phase was determined by use of the proposed algorithm. Experiments show that 0.1°C temperature resolution and up to 900°C temperature can be measured with good linearity.

  1. Mid-infrared imaging Fourier transform spectrometry for high power fiber laser irradiated fiberglass composites

    NASA Astrophysics Data System (ADS)

    Acosta, R. I.; Gross, K. C.; Perram, G. P.

    2012-03-01

    New measurement techniques to study continuous wave (CW) laser-material interactions are emerging with the ability to monitor the evolving, spatial distribution of the state of the surface-gas boundary layer. A qualitative analysis of gas phase combustion plumes above the surface of laser irradiated fiberglass composites is developed from fast framing hyperspectral imagery observations. An imaging Fourier Transform Spectrometer (IFTS) operating in the mid-infrared (MWIR) with high framing rate has recently been developed at the Air Force Institute of Technology (AFIT) in collaboration with Telops Inc. A 320 x 256 indium antimonide (InSb) focal plane array with spectral response from 1.5 - 5.5 μm is mated with a Michelson interferometer to achieve spectral resolutions as high as 0.25 cm-1. The very fast 16- tap InSb array frames at 1.9 kHz for the full 320 x 256 frame size. The single pixel field of view of 0.3 mrad provides a spatial resolution of 1 mm at the minimum focal distance of 3 m. Painted and unpainted fiberglass composites are irradiated with a 1064 nm CW Nd:YAG laser for 60 s at 100 W in air at atmospheric pressure. Selective emission in the region of 2100 - 3200 cm-1 is readily evident and is used to develop a time-dependent spatial map of both temperature and plume constituents. The time evolution of gas phase combustion products such as CO and CO2 molecules are monitored, with a spectral resolution of 2 cm-1. High-speed imagery is obtained using a low-pass filter for the interferograms, illustrating significant turbulent behavior during laser irradiation. Spatial brightness temperature maps exceed 600 K. Spatial variation in the ratio of [CO2]/[CO] indicates an interplay between heterogeneous and homogeneous kinetics.

  2. Fourier transform holography with high harmonic spectra for attosecond imaging applications.

    PubMed

    Williams, Gareth O; Gonzalez, A I; Künzel, S; Li, L; Lozano, M; Oliva, E; Iwan, B; Daboussi, S; Boutu, W; Merdji, H; Fajardo, M; Zeitoun, Ph

    2015-07-01

    We demonstrate a method of using a Fourier holographic technique to utilize attosecond soft x-ray pulses to image nanometer-scale objects. A discrete frequency comb of laser-generated high-order harmonics, yielding a train of attosecond pulses, has been used to record spatially and spectrally resolved images. The individual wavelengths were also combined to form a single image, albeit with lower spatial resolution, demonstrating the applicability of the method to using isolated attosecond pulses with continuous bandwidths. PMID:26125403

  3. Identification of Earthquake Induced Damage Areas Using Fourier Transform and SPOT HRVIR Pan Images.

    PubMed

    Sertel, Elif

    2009-01-01

    A devastating earthquake with a magnitude of Mw 7.4 occurred on the North Anatolian Fault Zone (NAFZ) of Turkey on August 17, 1999 at 00:01:39 UTC (3:01 a.m. local time). The aim of this study is to propose a new approach to automatically identify earthquake induced damage areas which can provide valuable information to support emergency response and recovery assessment procedures. This research was conducted in the Adapazari inner city, covering a 3 × 3 km area, where 11,373 buildings collapsed as a result of the earthquake. SPOT high resolution visible infrared (HRVIR) Pan images obtained before (25 June 1999) and after (4 October 1999) the earthquake were used in the study. Five steps were employed to conduct the research and these are: (i) geometric and radiometric correction of satellite images, (ii) Fast Fourier Transform (FFT) of pre- and post-earthquake images and filtering the images in frequency domain, (iii) generating difference image using Inverse Fast Fourier Transform (IFFT) pre- and post- earthquake images, (iv) application of level slicing to difference image to identify the earthquake-induced damages, (v) accuracy assessment of the method using ground truth obtained from a 1/5,000 scale damage map. The total accuracy obtained in the research is 80.19 %, illustrating that the proposed method can be successfully used to automatically identify earthquake-induced damage areas. PMID:22573966

  4. Nonnegative image reconstruction from sparse Fourier data: a new deconvolution algorithm

    NASA Astrophysics Data System (ADS)

    Bonettini, S.; Prato, M.

    2010-09-01

    This paper deals with image restoration problems where the data are nonuniform samples of the Fourier transform of the unknown object. We study the inverse problem in both semidiscrete and fully discrete formulations, and our analysis leads to an optimization problem involving the minimization of the data discrepancy under nonnegativity constraints. In particular, we show that such a problem is equivalent to a deconvolution problem in the image space. We propose a practical algorithm, based on the gradient projection method, to compute a regularized solution in the discrete case. The key point in our deconvolution-based approach is that the fast Fourier transform can be employed in the algorithm implementation without the need of preprocessing the data. A numerical experimentation on simulated and real data from the NASA RHESSI mission is also performed.

  5. Development of a multi-Fourier-transform interferometer: imaging experiments in millimeter and submillimeter wave bands

    NASA Astrophysics Data System (ADS)

    Ohta, Izumi S.; Hattori, Makoto; Matsuo, Hiroshi

    2007-05-01

    We have developed a millimeter and submillimeter Michelson-type bolometric interferometer based on a Martin-Puplett-type Fourier-transform spectrometer named multi-Fourier-transform interferometer (MuFT). We have succeeded in proving that the MuFT is capable of performing broadband imaging observations as theoretically proposed by our previous paper (OHM) [Appl. Opt. 45, 2576 (2006)]. We succeeded in acquiring the mutual coherence signal for an extended source in broadband. By analyzing the obtained mutual coherence signal following the formula proposed in OHM, 2D source images for each wavenumber from 5 cm-1 (150 GHz) to 35 cm-1 (1.05 THz) with a wavenumber interval of 0.4 cm-1 (12 GHz) were successfully extracted. The large dynamic range advantage of the MuFT proposed in OHM was confirmed experimentally.

  6. Development of a multi-Fourier-transform interferometer: imaging experiments in millimeter and submillimeter wave bands.

    PubMed

    Ohta, Izumi S; Hattori, Makoto; Matsuo, Hiroshi

    2007-05-20

    We have developed a millimeter and submillimeter Michelson-type bolometric interferometer based on a Martin-Puplett-type Fourier-transform spectrometer named multi-Fourier-transform interferometer (MuFT). We have succeeded in proving that the MuFT is capable of performing broadband imaging observations as theoretically proposed by our previous paper (OHM) [Appl. Opt. 45, 2576 (2006)]. We succeeded in acquiring the mutual coherence signal for an extended source in broadband. By analyzing the obtained mutual coherence signal following the formula proposed in OHM, 2D source images for each wavenumber from 5 cm(-1) (150 GHz) to 35 cm(-1) (1.05 THz) with a wavenumber interval of 0.4 cm(-1) (12 GHz) were successfully extracted. The large dynamic range advantage of the MuFT proposed in OHM was confirmed experimentally. PMID:17514233

  7. 3D spectral imaging with synchrotron Fourier transform infrared spectro-microtomography.

    PubMed

    Martin, Michael C; Dabat-Blondeau, Charlotte; Unger, Miriam; Sedlmair, Julia; Parkinson, Dilworth Y; Bechtel, Hans A; Illman, Barbara; Castro, Jonathan M; Keiluweit, Marco; Buschke, David; Ogle, Brenda; Nasse, Michael J; Hirschmugl, Carol J

    2013-09-01

    We report Fourier transform infrared spectro-microtomography, a nondestructive three-dimensional imaging approach that reveals the distribution of distinctive chemical compositions throughout an intact biological or materials sample. The method combines mid-infrared absorption contrast with computed tomographic data acquisition and reconstruction to enhance chemical and morphological localization by determining a complete infrared spectrum for every voxel (millions of spectra determined per sample). PMID:23913258

  8. Multicomponent FM demodulation of speech based on the short-time Fourier transform (STFT) phase

    NASA Astrophysics Data System (ADS)

    Nelson, Douglas J.

    2001-03-01

    Speech is a signal which is produced as a combination of frication and a quasi periodic train of glottal pulses excites the vocal tract and causes it to resonate. Information is encoded on the signal as the vocal tract changes configuration, resulting in a rapid change of the resonant frequencies. We develop methods, based on differentiation of the short time Fourier transform (STFT) phase, which effectively demodulates the speech signal and produces accurate, high resolution time-frequency estimates of both the resonances and the signal excitation. The method effectively condenses the STFT surface along curves representing the instantaneous frequencies of the vocal tract resonances and the channel group delay function.

  9. Universal and special keys based on phase-truncated Fourier transform

    NASA Astrophysics Data System (ADS)

    Qin, Wan; Peng, Xiang; Meng, Xiangfeng; Gao, Bruce

    2011-08-01

    We propose a novel optical asymmetric cryptosystem based on a phase-truncated Fourier transform. Two decryption keys independent of each other are generated. They are referred to as universal key and special key, respectively. Each of them can be used for decryption independently in absence of the other. The universal key is applicable to decrypt any ciphertext encoded by the same encryption key, but with poor legibility. On the contrary, the special key is adequate for legible decryption, but only valid for one ciphertext corresponding to the specified plaintext. A set of simulation results show the interesting performance of two types of decryption keys.

  10. A Fourier transform telescope for sub-arcsecond imaging of X-rays and gamma rays

    NASA Technical Reports Server (NTRS)

    Crannell, C. J.; Orwig, L. E.; Hurford, G. J.; Prince, T. A.

    1986-01-01

    This paper describes a Fourier transform telescope designed to image solar flare X-rays and gamma rays at energies up to 1 MeV with arcsec resolution. The imaging technique makes use of a bigrid collimator divided into a number of smaller areas called subcollimators. The grids in each subcollimator consist of a set of linear apertures so configured that each subcollimator provides a measurement of a single Fourier component of the angular distribution of the source. The imaging concept is therefore a mathematical analog to aperture synthesis in radio astronomy. For X-ray and gamma-ray astronomy, this approach has significant advantages in terms of relaxed requirements for astronomy, this approach has significant advantages in terms of relaxed requirements for position sensitivity in the detector and for control of grid alignment in the large scale telescope structure. The concept of the Fourier transform telescope will be illustrated with numerical parameters of a version now under study for the Pinhole/Occulter Facility.

  11. Terahertz holography for imaging amplitude and phase objects.

    PubMed

    Hack, Erwin; Zolliker, Peter

    2014-06-30

    A non-monochromatic THz Quantum Cascade Laser and an uncooled micro-bolometer array detector with VGA resolution are used in a beam-splitter free holographic set-up to measure amplitude and phase objects in transmission. Phase maps of the diffraction pattern are retrieved using the Fourier transform carrier fringe method; while a Fresnel-Kirchhoff back propagation algorithm is used to reconstruct the complex object image. A lateral resolution of 280 µm and a relative phase sensitivity of about 0.5 rad are estimated from reconstructed images of a metallic Siemens star and a polypropylene test structure, respectively. Simulations corroborate the experimental results. PMID:24977861

  12. A non-linear preprocessing for opto-digital image encryption using multiple-parameter discrete fractional Fourier transform

    NASA Astrophysics Data System (ADS)

    Azoug, Seif Eddine; Bouguezel, Saad

    2016-01-01

    In this paper, a novel opto-digital image encryption technique is proposed by introducing a new non-linear preprocessing and using the multiple-parameter discrete fractional Fourier transform (MPDFrFT). The non-linear preprocessing is performed digitally on the input image in the spatial domain using a piecewise linear chaotic map (PLCM) coupled with the bitwise exclusive OR (XOR). The resulting image is multiplied by a random phase mask before applying the MPDFrFT to whiten the image. Then, a chaotic permutation is performed on the output of the MPDFrFT using another PLCM different from the one used in the spatial domain. Finally, another MPDFrFT is applied to obtain the encrypted image. The parameters of the PLCMs together with the multiple fractional orders of the MPDFrFTs constitute the secret key for the proposed cryptosystem. Computer simulation results and security analysis are presented to show the robustness of the proposed opto-digital image encryption technique and the great importance of the new non-linear preprocessing introduced to enhance the security of the cryptosystem and overcome the problem of linearity encountered in the existing permutation-based opto-digital image encryption schemes.

  13. Fast Fourier transform-based Retinex and alpha-rooting color image enhancement

    NASA Astrophysics Data System (ADS)

    Grigoryan, Artyom M.; Agaian, Sos S.; Gonzales, Analysa M.

    2015-05-01

    Efficiency in terms of both accuracy and speed is highly important in any system, especially when it comes to image processing. The purpose of this paper is to improve an existing implementation of multi-scale retinex (MSR) by utilizing the fast Fourier transforms (FFT) within the illumination estimation step of the algorithm to improve the speed at which Gaussian blurring filters were applied to the original input image. In addition, alpha-rooting can be used as a separate technique to achieve a sharper image in order to fuse its results with those of the retinex algorithm for the sake of achieving the best image possible as shown by the values of the considered color image enhancement measure (EMEC).

  14. Depth resolved hyperspectral imaging spectrometer based on structured light illumination and Fourier transform interferometry

    PubMed Central

    Choi, Heejin; Wadduwage, Dushan; Matsudaira, Paul T.; So, Peter T.C.

    2014-01-01

    A depth resolved hyperspectral imaging spectrometer can provide depth resolved imaging both in the spatial and the spectral domain. Images acquired through a standard imaging Fourier transform spectrometer do not have the depth-resolution. By post processing the spectral cubes (x, y, λ) obtained through a Sagnac interferometer under uniform illumination and structured illumination, spectrally resolved images with depth resolution can be recovered using structured light illumination algorithms such as the HiLo method. The proposed scheme is validated with in vitro specimens including fluorescent solution and fluorescent beads with known spectra. The system is further demonstrated in quantifying spectra from 3D resolved features in biological specimens. The system has demonstrated depth resolution of 1.8 μm and spectral resolution of 7 nm respectively. PMID:25360367

  15. Evaluation of Fourier transform coefficients for the diagnosis of rheumatoid arthritis from diffuse optical tomography images

    NASA Astrophysics Data System (ADS)

    Montejo, Ludguier D.; Jia, Jingfei; Kim, Hyun K.; Hielscher, Andreas H.

    2013-03-01

    We apply the Fourier Transform to absorption and scattering coefficient images of proximal interphalangeal (PIP) joints and evaluate the performance of these coefficients as classifiers using receiver operator characteristic (ROC) curve analysis. We find 25 features that yield a Youden index over 0.7, 3 features that yield a Youden index over 0.8, and 1 feature that yields a Youden index over 0.9 (90.0% sensitivity and 100% specificity). In general, scattering coefficient images yield better one-dimensional classifiers compared to absorption coefficient images. Using features derived from scattering coefficient images we obtain an average Youden index of 0.58 +/- 0.16, and an average Youden index of 0.45 +/- 0.15 when using features from absorption coefficient images.

  16. Application of short-coherence lensless Fourier-transform digital holography in imaging through diffusive medium

    NASA Astrophysics Data System (ADS)

    Zhang, Yizhuo; Situ, Guohai; Pedrini, Giancarlo; Wang, Dayong; Javidi, Bahram; Osten, Wolfgang

    2013-01-01

    We propose a short-coherence lensless Fourier-transform digital holography for imaging through scattering media. The technique utilizes a low-power cw diode laser with short temporal coherence and enables the selection of the early-arriving photons through a diffusive medium by interfering with a spherical reference beam from the same source. An averaging technique is introduced to extract the weak signal from strong background noise. The proposed technique is verified using both theoretical analysis and experimental demonstration by imaging an object through a 3-mm-thick chicken breast tissue.

  17. High-resolution retinal imaging using adaptive optics and Fourier-domain optical coherence tomography

    SciTech Connect

    Olivier, Scot S.; Werner, John S.; Zawadzki, Robert J.; Laut, Sophie P.; Jones, Steven M.

    2010-09-07

    This invention permits retinal images to be acquired at high speed and with unprecedented resolution in three dimensions (4.times.4.times.6 .mu.m). The instrument achieves high lateral resolution by using adaptive optics to correct optical aberrations of the human eye in real time. High axial resolution and high speed are made possible by the use of Fourier-domain optical coherence tomography. Using this system, we have demonstrated the ability to image microscopic blood vessels and the cone photoreceptor mosaic.

  18. Spectral calibration for infrared hyperspectral imaging Fourier transform spectrometer based on absorption peaks

    NASA Astrophysics Data System (ADS)

    Li, YaSheng; Chen, Yan; Liao, Ningfang; Lyu, Hang; He, Shufang; Wan, Lifang

    2015-08-01

    A new calibration method for infrared hyperspectral imaging Fourier transform spectrometer is presented. Two kinds of common materials as Polypropylene (PP) and Polyethylene Terephthalate (PET) films which have special absorption peaks in the infrared band were used in the calibration experiment. As the wavelengths at the sharp absorption peaks of the films are known, an infrared imaging spectrometer can be calibrated on spectra with two or three peaks. With high precision and stability, this method simplifies the calibration work. It is especially appropriate for the measuring condition with a lack of calibration equipment or with inconvenience to calibrate the multiple light sources outdoors.

  19. Quantitative zonal differentiation of articular cartilage by microscopic magnetic resonance imaging, polarized light microscopy, and Fourier-transform infrared imaging.

    PubMed

    Lee, Ji Hyun; Xia, Yang

    2013-06-01

    This study aimed to synchronize the zonal differentiation of the full-thickness articular cartilage by three micro-imaging techniques, namely microscopic magnetic resonance imaging (µMRI), polarized light microscopy (PLM), and Fourier-transform infrared imaging (FTIRI). Eighteen cartilage-bone blocks from three canine humeral joints were imaged by: (a) µMRI T2 relaxation at 0° and 55° orientations in a 7 T magnetic field, (b) PLM optical retardation and azimuthal angle, and (c) FTIRI amide I and amide II anisotropies at 0° and 90° polarizations relative to the articular surface. In addition, µMRI T1 relaxation was imaged before and after the tissue being immersed in gadolinium (contrast agent) solution, to calculate the proteoglycan concentration. A set of previously established criteria in cartilage imaging was revised. The new criteria could simultaneously correlate the thicknesses of the three consecutive subtissue zones in articular cartilage among these imaging techniques. PMID:23533143

  20. Fourier Imaging Correlation Spectroscopy for Studies of Sub-Cellular Dynamics and Biomolecular Conformation Transition Pathways

    NASA Astrophysics Data System (ADS)

    Marcus, Andrew

    2010-03-01

    Novel high signal-to-noise spectroscopic experiments that probe the dynamics of fluorescently labeled macromolecules have the potential to reveal complex intracellular biochemical mechanisms, or the slow relaxations of soft matter systems. Fourier imaging correlation spectroscopy (FICS) is a phase-selective approach to fluorescence fluctuation spectroscopy that employs a unique route to elevate signal levels while acquiring detailed information about microscopic coordinate trajectories. In this talk, I will illustrate the broad applicability of this approach by discussing two recent studies. The anomalous sub-diffusive dynamics of mitochondria in budding yeast are characterized using FICS, and provide detailed, length-scale dependent information about the influence of specific cytoskeletal elements on the movements of this organelle. We find that non-equilibrium forces associated with actin polymerization lead to a 1.5-fold enhancement of the long-time mitochondrial diffusion coefficient, and a transient sub-diffusive temporal scaling of the mean-square displacement. These non-equilibrium dynamics are a predominant factor in driving mitochondrial transport. In another set of experiments, polarization-modulated FICS simultaneously captures information about the internal conformation fluctuations and molecular translational dynamics of the fluorescent protein DsRed. By implementing a four-point correlation analysis, we construct two-dimensional spectral densities and joint distribution functions that determine temporal correlations of center-of-mass and anisotropy coordinates over successive time intervals. These four-point functions reveal statistically meaningful transition pathways between different optical conformations of the DsRed protein. The FICS method is well suited to investigate the dynamics of a broad range of heterogeneous systems, which include the molecular motions of glass forming liquids.

  1. Imaging Fourier transform spectroscopy of the boundary layer plume from laser irradiated polymers and carbon materials

    NASA Astrophysics Data System (ADS)

    Acosta, Roberto I.

    The high-energy laser (HEL) lethality community needs for enhanced laser weapons systems requires a better understanding of a wide variety of emerging threats. In order to reduce the dimensionality of laser-materials interaction it is necessary to develop novel predictive capabilities of these events. The objective is to better understand the fundamentals of laser lethality testing by developing empirical models from hyperspectral imagery, enabling a robust library of experiments for vulnerability assessments. Emissive plumes from laser irradiated fiberglass reinforced polymers (FRP), poly(methyl methacrylate) (PMMA) and porous graphite targets were investigated primarily using a mid-wave infrared (MWIR) imaging Fourier transform spectrometer (FTS). Polymer and graphite targets were irradiated with a continuous wave (cw) fiber lasers. Data was acquired with a spectral resolution of 2 cm-1 and spatial resolution as high as 0.52 mm2 per pixel. Strong emission from H2O, CO, CO2 and hydrocarbons were observed in the MWIR between 1900-4000 cm-1. A single-layer radiative transfer model was developed to estimate spatial maps of temperature and column densities of CO and CO2 from the hyperspectral imagery of the boundary layer plume. The spectral model was used to compute the absorption cross sections of CO and CO2, using spectral line parameters from the high temperature extension of the HITRAN. Also, spatial maps of gas-phase temperature and methyl methacrylate (MMA) concentration were developed from laser irradiated carbon black-pigmented PMMA at irradiances of 4-22 W/cm2. Global kinetics interplay between heterogeneous and homogeneous combustion kinetics are shown from experimental observations at high spatial resolutions. Overall the boundary layer profile at steady-state is consistent with CO being mainly produced at the surface by heterogeneous reactions followed by a rapid homogeneous combustion in the boundary layer towards buoyancy.

  2. Mapping agroecological zones and time lag in vegetation growth by means of Fourier analysis of time series of NDVI images

    NASA Technical Reports Server (NTRS)

    Menenti, M.; Azzali, S.; Verhoef, W.; Van Swol, R.

    1993-01-01

    Examples are presented of applications of a fast Fourier transform algorithm to analyze time series of images of Normalized Difference Vegetation Index values. The results obtained for a case study on Zambia indicated that differences in vegetation development among map units of an existing agroclimatic map were not significant, while reliable differences were observed among the map units obtained using the Fourier analysis.

  3. Fourier synthesis image reconstruction by use of one-dimensional position-sensitive detectors.

    PubMed

    Kotoku, Jun'ichi; Makishima, Kazuo; Okada, Yuu; Negoro, Hitoshi; Terada, Yukikatsu; Kaneda, Hidehiro; Oda, Minoru

    2003-07-10

    An improvement of Fourier synthesis optics for hard x-ray imaging is described, and the basic performance of the new optics is confirmed through numerical simulations. The original concept of the Fourier synthesis imager utilizes nonposition-sensitive hard x-ray detectors coupled to individual bigrid modulation collimators. The improved concept employs a one-dimensional position-sensitive detector (such as a CdTe strip detector) instead of the second grid layer of each bigrid modulation collimator. This improves the imaging performance in several respects over the original design. One performance improvement is a two-fold increase in the average transmission, from 1/4 to 1/2. The second merit is that both the sine and cosine components can be derived from a single grid-detector module, and hence the number of imaging modules can be halved. Furthermore, it provides information along the depth direction simultaneously. This in turn enables a three-dimensional imaging hard x-ray microscope for medical diagnostics, incorporating radioactive tracers. A conceptual design of such a microscope is presented, designed to provide a field of view of 4 mm and a spatial resolution of 400 microm. PMID:12856730

  4. Phase difference map interpretation of Mach diamond interferometric patterns by Fourier Transform Methods

    NASA Astrophysics Data System (ADS)

    Rodrguez, F.; Dorro, B. V.; Doval, A. F.

    2008-04-01

    The development of a new interferometric evaluation system has allowed the detailed quantitative characterization of complex Mach diamond patterns in quasi stationary jets of compressed air provided by a Laval nozzle usually employed for laser cutting of ceramic materials. The application of a Mach-Zehnder interferometer in order to observe the stationary shock wave patterns provides fringe patterns that are recorded through a CMOS camera. Their optical phase is extracted through two differential phase evaluation methods that use the Fourier Transform as a fundamental tool. On the basis of the available data, the analysis of the pressure distribution and also of the shock wave patterns that occur in the free jet stream allows us to confirm the hypothesis previously established related with the main characteristics of a free jet.

  5. In vivo imaging of the rodent eye with swept source/Fourier domain OCT.

    PubMed

    Liu, Jonathan J; Grulkowski, Ireneusz; Kraus, Martin F; Potsaid, Benjamin; Lu, Chen D; Baumann, Bernhard; Duker, Jay S; Hornegger, Joachim; Fujimoto, James G

    2013-02-01

    Swept source/Fourier domain OCT is demonstrated for in vivo imaging of the rodent eye. Using commercial swept laser technology, we developed a prototype OCT imaging system for small animal ocular imaging operating in the 1050 nm wavelength range at an axial scan rate of 100 kHz with ~6 µm axial resolution. The high imaging speed enables volumetric imaging with high axial scan densities, measuring high flow velocities in vessels, and repeated volumetric imaging over time. The 1050 nm wavelength light provides increased penetration into tissue compared to standard commercial OCT systems at 850 nm. The long imaging range enables multiple operating modes for imaging the retina, posterior eye, as well as anterior eye and full eye length. A registration algorithm using orthogonally scanned OCT volumetric data sets which can correct motion on a per A-scan basis is applied to compensate motion and merge motion corrected volumetric data for enhanced OCT image quality. Ultrahigh speed swept source OCT is a promising technique for imaging the rodent eye, proving comprehensive information on the cornea, anterior segment, lens, vitreous, posterior segment, retina and choroid. PMID:23412778

  6. Quantitative phase imaging of arthropods

    NASA Astrophysics Data System (ADS)

    Sridharan, Shamira; Katz, Aron; Soto-Adames, Felipe; Popescu, Gabriel

    2015-11-01

    Classification of arthropods is performed by characterization of fine features such as setae and cuticles. An unstained whole arthropod specimen mounted on a slide can be preserved for many decades, but is difficult to study since current methods require sample manipulation or tedious image processing. Spatial light interference microscopy (SLIM) is a quantitative phase imaging (QPI) technique that is an add-on module to a commercial phase contrast microscope. We use SLIM to image a whole organism springtail Ceratophysella denticulata mounted on a slide. This is the first time, to our knowledge, that an entire organism has been imaged using QPI. We also demonstrate the ability of SLIM to image fine structures in addition to providing quantitative data that cannot be obtained by traditional bright field microscopy.

  7. Automated segmentation of intramacular layers in Fourier domain optical coherence tomography structural images from normal subjects

    PubMed Central

    Zhang, Xusheng; Yousefi, Siavash; An, Lin

    2012-01-01

    Abstract. Segmentation of optical coherence tomography (OCT) cross-sectional structural images is important for assisting ophthalmologists in clinical decision making in terms of both diagnosis and treatment. We present an automatic approach for segmenting intramacular layers in Fourier domain optical coherence tomography (FD-OCT) images using a searching strategy based on locally weighted gradient extrema, coupled with an error-removing technique based on statistical error estimation. A two-step denoising preprocess in different directions is also employed to suppress random speckle noise while preserving the layer boundary as intact as possible. The algorithms are tested on the FD-OCT volume images obtained from four normal subjects, which successfully identify the boundaries of seven physiological layers, consistent with the results based on manual determination of macular OCT images. PMID:22559689

  8. In-vivo human corneal nerve imaging using Fourier-domain OCT

    NASA Astrophysics Data System (ADS)

    Shin, Jun Geun; Lee, Byeong Ha; Eom, Tae Joong; Hwang, Ho Sik

    2015-03-01

    We have imaged human corneal nerve bundles by using real-time Fourier-domain OCT (FD-OCT). Corneal nerves contribute to the maintenance of healthy ocular surface owing to their trophic influences on the corneal epithelium. The FD-OCT system was based on a swept laser of a 50 kHz sweeping rate and 1.31 μm center wavelength. At the area including sclera, limbus, and cornea, we could successfully get the in-vivo tomograms of the corneal nerve bundles. The scan range was 5 x 5mm. In this study, the A-scan images in each B-scan were realigned to have a flat air-surface boundary in the final B-scan image. With this effort, we could align corneal nerve bundle in a same depth and get the 3D image showing the branched and threadlike corneal nerve bundles.

  9. Phase-image-based content-addressable holographic data storage

    NASA Astrophysics Data System (ADS)

    John, Renu; Joseph, Joby; Singh, Kehar

    2004-03-01

    We propose and demonstrate the use of phase images for content-addressable holographic data storage. Use of binary phase-based data pages with 0 and π phase changes, produces uniform spectral distribution at the Fourier plane. The absence of strong DC component at the Fourier plane and more intensity of higher order spatial frequencies facilitate better recording of higher spatial frequencies, and improves the discrimination capability of the content-addressable memory. This improves the results of the associative recall in a holographic memory system, and can give low number of false hits even for small search arguments. The phase-modulated pixels also provide an opportunity of subtraction among data pixels leading to better discrimination between similar data pages.

  10. Remote measurement of highly toxic vapors by scanning imaging Fourier-transform spectrometry

    NASA Astrophysics Data System (ADS)

    Harig, Roland; Rusch, Peter; Dyer, Chris; Jones, Anita; Moseley, Richard; Truscott, Benjamin

    2005-11-01

    In the case of chemical accidents, terrorist attacks, or war, hazardous compounds may be released into the atmosphere. Remote sensing by Fourier-transform infrared spectrometry allows identification and quantification of these hazardous clouds. The output of current standoff detection systems is a yes/no decision by an automatic identification algorithm that analyses the measured spectrum. The interpretation of the measured spectrum by the operator is complicated and thus this task requires an expert. Even if a scanning system is used for surveillance of a large area the operator is dependent on the decision of the algorithm. In contrast to that, imaging systems allow automatic identification but also simple interpretation of the result, the image of the cloud. Therefore, an imaging spectrometer, the scanning infrared gas imaging system (SIGIS) has been developed. The system is based on an interferometer with a single detector element (Bruker OPAG 22) in combination with a telescope and a synchronised scanning mirror. The results of the analyses of the spectra are displayed by an overlay of a false colour image, the "chemical cloud image", on a video image. In this work, the first application of the system as chemical warfare agent identification and imaging system is described. The system, the data analysis method, and results of measurements of chemical warfare agents are presented.

  11. Broadband photonic microwave phase shifter based on controlling two RF modulation sidebands via a Fourier-domain optical processor.

    PubMed

    Yang, J; Chan, E H W; Wang, X; Feng, X; Guan, B

    2015-05-01

    An all-optical photonic microwave phase shifter that can realize a continuous 360° phase shift over a wide frequency range is presented. It is based on the new concept of controlling the amplitude and phase of the two RF modulation sidebands via a Fourier-domain optical processor. The operating frequency range of the phase shifter is largely increased compared to the previously reported Fourier-domain optical processor based phase shifter that uses only one RF modulation sideband. This is due to the extension of the lower RF operating frequency by designing the amplitude and phase of one of the RF modulation sidebands while the other sideband is designed to realize the required RF signal phase shift. The two-sideband amplitude-and-phase-control based photonic microwave phase shifter has a simple structure as it only requires a single laser source, a phase modulator, a Fourier-domain optical processor and a single photodetector. Investigation on the bandwidth limitation problem in the conventional Fourier-domain optical processor based phase shifter is presented. Comparisons between the measured phase shifter output RF amplitude and phase responses with theory, which show excellent agreement, are also presented for the first time. Experimental results demonstrate the full -180° to + 180° phase shift with little RF signal amplitude variation of less than 3 dB and with a phase deviation of less than 4° over a 7.5 GHz to 26.5 GHz frequency range, and the phase shifter exhibits a long term stable performance. PMID:25969298

  12. Phase imaging with thermal neutrons

    NASA Astrophysics Data System (ADS)

    Allman, Brendan E.; Nugent, Keith A.

    2006-11-01

    Across four decades, Sam Werner has built and performed elegant neutron interferometry experiments to measure a variety of quantum mechanical phases. These experiments have stringent requirements on experimental conditions and neutron beam conditioning. However, since refractive variations within a sample redistribute neutron intensity transverse to the propagation direction, a simple experimental geometry permits non-interferometric phase measurement and relaxes beam-conditioning requirements. This phase imaging technique, based on the transport of intensity equation, has advantages of allowing weakly absorbing samples to be radiographed at greatly reduced radiation doses, and enabling the use of polychromatic neutrons to increase flux and speed imaging. Furthermore, using other radiations, phase vortices like those of the Aharonov-Bohm effects have been observed.

  13. Breast cancer detection from MR images through an auto-probing discrete Fourier transform system.

    PubMed

    Sim, K S; Chia, F K; Nia, M E; Tso, C P; Chong, A K; Abbas, Siti Fathimah; Chong, S S

    2014-06-01

    A computer-aided detection auto-probing (CADAP) system is presented for detecting breast lesions using dynamic contrast enhanced magnetic resonance imaging, through a spatial-based discrete Fourier transform. The stand-alone CADAP system reduces noise, refines region of interest (ROI) automatically, and detects the breast lesion with minimal false positive detection. The lesions are then classified and colourised according to their characteristics, whether benign, suspicious or malignant. To enhance the visualisation, the entire analysed ROI is constructed into a 3-D image, so that the user can diagnose based on multiple views on the ROI. The proposed method has been applied to 101 sets of digital images, and the results compared with the biopsy results done by radiologists. The proposed scheme is able to identify breast cancer regions accurately and efficiently. PMID:24736203

  14. Improving the time efficiency of the Fourier synthesis method for slice selection in magnetic resonance imaging.

    PubMed

    Tahayori, B; Khaneja, N; Johnston, L A; Farrell, P M; Mareels, I M Y

    2016-01-01

    The design of slice selective pulses for magnetic resonance imaging can be cast as an optimal control problem. The Fourier synthesis method is an existing approach to solve these optimal control problems. In this method the gradient field as well as the excitation field are switched rapidly and their amplitudes are calculated based on a Fourier series expansion. Here, we provide a novel insight into the Fourier synthesis method via representing the Bloch equation in spherical coordinates. Based on the spherical Bloch equation, we propose an alternative sequence of pulses that can be used for slice selection which is more time efficient compared to the original method. Simulation results demonstrate that while the performance of both methods is approximately the same, the required time for the proposed sequence of pulses is half of the original sequence of pulses. Furthermore, the slice selectivity of both sequences of pulses changes with radio frequency field inhomogeneities in a similar way. We also introduce a measure, referred to as gradient complexity, to compare the performance of both sequences of pulses. This measure indicates that for a desired level of uniformity in the excited slice, the gradient complexity for the proposed sequence of pulses is less than the original sequence. PMID:26602859

  15. Utilization of a liquid crystal spatial light modulator in a gray scale detour phase method for Fourier holograms.

    PubMed

    Makey, Ghaith; El-Daher, Moustafa Sayem; Al-Shufi, Kanj

    2012-11-10

    This paper introduces a new modification for the well-known binary detour phase method, which is largely used to represent Fourier holograms; the modification utilizes gray scale level control provided by a liquid crystal spatial light modulator to improve the traditional binary detour phase. Results are shown by both simulation and experiment. PMID:23142903

  16. SITELLE: a wide-field imaging Fourier transform spectrometer for the Canada-France-Hawaii Telescope

    NASA Astrophysics Data System (ADS)

    Drissen, L.; Bernier, A.-P.; Rousseau-Nepton, L.; Alarie, A.; Robert, C.; Joncas, G.; Thibault, S.; Grandmont, F.

    2010-07-01

    We describe the concept of a new instrument for the Canada-France-Hawaii telescope (CFHT), SITELLE (Spectromètre Imageur à Transformée de Fourier pour l'Etude en Long et en Large de raies d'Emission), as well as a science case and a technical study of its preliminary design. SITELLE will be an imaging Fourier transform spectrometer capable of obtaining the visible (350 nm - 950 nm) spectrum of every source of light in a field of view of 15 arcminutes, with 100% spatial coverage and a spectral resolution ranging from R = 1 (deep panchromatic image) to R = 104 (for gas dynamics). SITELLE will cover a field of view 100 to 1000 times larger than traditional integral field spectrographs, such as GMOS-IFU on Gemini or the future MUSE on the VLT. It is a legacy from BEAR, the first imaging FTS installed on the CFHT and the direct successor of SpIOMM, a similar instrument attached to the 1.6-m telescope of the Observatoire du Mont-Mégantic in Québec. SITELLE will be used to study the structure and kinematics of HII regions and ejecta around evolved stars in the Milky Way, emission-line stars in clusters, abundances in nearby gas-rich galaxies, and the star formation rate in distant galaxies.

  17. Objective Morphological Quantification of Microscopic Images Using a Fast Fourier Transform (FFT) Analysis

    PubMed Central

    Taylor, Samuel E.; Cao, Tuoxin; Talauliker, Pooja M.; Lifshitz, Jonathan

    2016-01-01

    Quantification of immunohistochemistry (IHC) and immunofluorescence (IF) using image intensity depends on a number of variables. These variables add a subjective complexity in keeping a standard within and between laboratories. Fast Fourier Transformation (FFT) algorithms, however, allow for a rapid and objective quantification (via statistical analysis) using cell morphologies when the microscopic structures are oriented or aligned. Quantification of alignment is given in terms of a ratio of FFT intensity to the intensity of an orthogonal angle, giving a numerical value of the alignment of the microscopic structures. This allows for a more objective analysis than alternative approaches, which rely upon relative intensities.

  18. Analysis of the Advantages and Limitations of Stationary Imaging Fourier Transform Spectrometer. Revised

    NASA Technical Reports Server (NTRS)

    Beecken, Brian P.; Kleinman, Randall R.

    2004-01-01

    New developments in infrared sensor technology have potentially made possible a new space-based system which can measure far-infrared radiation at lower costs (mass, power and expense). The Stationary Imaging Fourier Transform Spectrometer (SIFTS) proposed by NASA Langley Research Center, makes use of new detector array technology. A mathematical model which simulates resolution and spectral range relationships has been developed for analyzing the utility of such a radically new approach to spectroscopy. Calculations with this forward model emulate the effects of a detector array on the ability to retrieve accurate spectral features. Initial computations indicate significant attenuation at high wavenumbers.

  19. High-resolution Fourier hologram synthesis from photographic images through computing the light field.

    PubMed

    Chen, Ni; Ren, Zhenbo; Lam, Edmund Y

    2016-03-01

    We present a technique for synthesizing the Fourier hologram of a three-dimensional scene from its light field. The light field captures the volumetric information of an object, and an important advantage is that it does not require coherent illumination, as in conventional holography. In this work, we show how to obtain a high-resolution digital hologram with the light field obtained from a series of photographic images captured along the optical axis. The method is verified both by simulations and experimentally captured light field. PMID:26974639

  20. Assessment of fibre orientation in reinforced concrete using Fourier image transform.

    PubMed

    Redon; Chermant; Chermant; Coster

    1998-09-01

    In this study, ribbon-shaped amorphous cast-iron fibres were used to reinforce a concrete matrix. X-ray photographs have been taken to detect fibres in situ. Their orientation has been investigated by automatic image analysis methods. However, this measurement should not be influenced by the digitization on the square frame of the analyser. For that purpose, the Fourier transform was used rather than the rose of direction method. This analysis revealed the transverse isotropic nature of the spatial arrangement of these fibres, whose axis of revolution corresponds to the concrete casting axis. Such a morphological characterization of the fibre-reinforced concrete reveals its mechanical behaviour. PMID:9767490

  1. [Determination of the sequencing of sealing and writing with Fourier IR microscopic chemical image system].

    PubMed

    Yang, Sheng-Jun; Zou, Duo-Sheng; Shi, Lin; Wang, Yan-Jun; Xie, Jing-Lan; Wang, Guo-Qiang

    2006-08-01

    Using Fourier-transform IR microscopic chemical image system, combined with surface scan and reflection mode, non-invasive fast identification of the sequencing of writing and sealing was carried out. Results indicate that sealing prior to writing leads to evident characteristic peaks of the ink in the IR spectra, while writing prior to sealing results in clear characteristic peaks of the stamp-pad ink in the IR spectra. The method features speediness, exactness, impersonality, and non-invasion to the sample. PMID:17058946

  2. Temperature measurement of an axisymmetric flame using phase shift holographic interferometry with fast Fourier transform

    NASA Astrophysics Data System (ADS)

    Tieng, S. M.; Lai, W. Z.

    Because of the importance of the temperature scalar measurements in combination diagonostics, application of phase shift holographic interferometry to temperature measurement of an axisymmetrically premixed flame was experimentally investigated. The test apparatus is an axisymmetric Bunsen burner. Propane of 99 percent purity is used as the gaseous fuel. A fast Fourier transform, a more efficient and accurate approach for Abel inversion, is used for reconstructed the axisymmetric temperature field from the interferometric data. The temperature distribution is compared with the thermocouple-measured values. The comparison shows that the proposed technique is satisfactory. The result errors are analyzed in detail. It is shown that this technique overcomes most of the earlier problems and limitations detrimental to the conventional holographic interferometry.

  3. Modeling the viscoplastic micromechanical response of two-phase materials using fast Fourier transforms

    SciTech Connect

    Lebensohn, Ricardo A; Lee, Sukbin; Rollett, Anthony D

    2009-01-01

    A viscoplastic approach using the Fast Fourier Transform (FFT) method for obtaining local mechanical response is utilized to study microstructure-property relationships in composite materials. Specifically, three-dimensional, two-phase digital materials containing isotropically coarsened particles surrounded by a matrix phase, generated through a Kinetic Monte Carlo Potts model for Ostwald ripening, are used as instantiations in order to calculate the stress and strain rate fields under uniaxial tension. The effects of the morphology of the matrix phase, the volume fraction and the contiguity of particles, and the polycrystallinity of matrix phase, on the stress and strain rate fields under uniaxial tension are examined. It is found that the first moments of the stress and strain rate fields have a different dependence on the particle volume fraction and the particle contiguity from their second moments. The average stresses and average strain rates of both phases and of the overall composite have rather simple relationships with the particle volume fraction whereas their standard deviations vary strongly, especially when the particle volume fraction is high, and the contiguity of particles has a noticeable effect on the mechanical response. It is also found that the shape of stress distribution in the BCC hard particle phase evolves as the volume fraction of particles in the composite varies, such that it agrees with the stress field in the BCC polycrystal as the volume of particles approaches unity. Finally, it is observed that the stress and strain rate fields in the microstructures with a polycrystalline matrix are less sensitive to changes in volume fraction and contiguity of particles.

  4. Neutron Phase Imaging and Tomography

    SciTech Connect

    Pfeiffer, F.; Gruenzweig, C.; Bunk, O.; Frei, G.; Lehmann, E.; David, C.

    2006-06-02

    We report how a setup consisting of three gratings yields quantitative two- and three-dimensional images depicting the quantum-mechanical phase shifts of neutron de Broglie wave packets induced by the influence of macroscopic objects. Since our approach requires only a little spatial and chromatic coherence it provides a more than 2 orders of magnitude higher efficiency than existing techniques. This dramatically reduces the required measurement time for computed phase tomography and opens up the way for three-dimensional investigations of previously inaccessible quantum-mechanical phase interactions of neutrons with matter.

  5. The Anatomy of Fourier-Based Correlation Image Velocimetry and Sources of Decorrelating Errors

    NASA Astrophysics Data System (ADS)

    Giarra, Matthew; Vlachos, Pavlos

    2015-11-01

    Particle image velocimetry (PIV) algorithms have recently been applied to photographs captured using a variety of techniques including schlieren, synchrotron x-ray, and microscope imaging. While the characteristics of these types of images differ greatly from those of particle images, virtually no analysis has been done to determine how these differences affect the performance of Fourier-based cross correlation (CC) algorithms. Here, we analyze schlieren, x-ray, and traditional PIV images to show that the signal-to-noise ratios (SNR) of their CCs vary across spectral wavenumbers, and that the assignment of a single SNR to the CC is an oversimplification that obfuscates the underlying source of the decorrelating errors. We will show that the failure of traditional algorithms to distinguish correlated from uncorrelated wavenumbers introduces secondary CC peaks that increase measurement uncertainty by decreasing the correlation peak-height ratio, and can cause the measurement to fail by overtaking the true peak. Finally, we introduce a new algorithm that mitigates these issues and increases measurement accuracy by automatically discriminating correlated wavenumbers with no a priori information about the images' contents.

  6. Fourier transform infared spectroscopic imaging for the identification of concealed drug residue particles and fingerprints

    NASA Astrophysics Data System (ADS)

    Ricci, Camilla; Chan, K. L. Andrew; Kazarian, Sergei G.

    2006-09-01

    Conventional FTIR spectroscopy and microscopy has been widely used in forensic science. New opportunities exist to obtain rapid chemical images and to enhance the sensitivity of detection of trace materials using attenuated total reflection (ATR) Fourier transform infrared (FTIR) spectroscopy coupled with a focal-plane array (FPA) detector. In this work, the sensitivity of ATR-FTIR spectroscopic imaging using three different kinds of ATR crystals (Ge coupled with an infrared microscope, ZnSe and diamond) and resulting in three different optical arrangements for the detection of model drug particles is discussed. Model systems of ibuprofen and paracetamol particles having a size below 32 micrometers have been prepared by sieving. The sensitivity level in the three different approaches has been compared and it has been found that both micro and macro-ATR imaging methods have proven to be a promising techniques for the identification of concealed drug particles. To demonstrate the power and applicability of FTIR chemical imaging to forensic research, various examples are discussed. This includes investigation of the changes of chemical nature of latent fingerprint residue under controlled conditions of humidity and temperature studied by ATR-FTIR imaging. This study demonstrates the potential of spectroscopic imaging for visualizing the chemical changes of fingerprints.

  7. Application of Fourier Domain OCT Imaging Technology to the Anterior Segment of the Human Eye

    NASA Astrophysics Data System (ADS)

    Wojtkowski, Maciej; Marcos, Susana; Ortiz, Sergio; Grulkowski, Ireneusz

    The anterior segment is the front part of the human eye, which forms the optical system and hence directly impacts vision. Traumatic or pathological changes in the anterior segment may lead to vision loss and, in some cases, even blindness. Since the eighteenth century, optical instrumentation for measuring and imaging the anterior segment of the human eye has been developing along with modern ophthalmology. The application of OCT to the anterior segment imaging is particularly of interest, since this could potentially provide substantial complementary information regarding the large-scale architecture of the cornea and the crystalline lens, or on small portions of tissue imaged with high spatial resolutions comparable to regular microscopy. Especially an introduction of Fourier domain detection in OCT has opened new frontiers in OCT ophthalmic applications. The resultant substantial speed improvement enables rapid image acquisition, helping to reduce artifacts due to patient motion. Thus, it is currently possible to perform high-speed, in vivo, three-dimensional volumetric imaging over large scales within a reasonable time limit and without reducing system sensitivity. This chapter describes the state-of the art OCT technology dedicated to anterior segment imaging and indicates all important parameters which are required for optimization of the performance of OCT instrument.

  8. Tensor representation of color images and fast 2D quaternion discrete Fourier transform

    NASA Astrophysics Data System (ADS)

    Grigoryan, Artyom M.; Agaian, Sos S.

    2015-03-01

    In this paper, a general, efficient, split algorithm to compute the two-dimensional quaternion discrete Fourier transform (2-D QDFT), by using the special partitioning in the frequency domain, is introduced. The partition determines an effective transformation, or color image representation in the form of 1-D quaternion signals which allow for splitting the N × M-point 2-D QDFT into a set of 1-D QDFTs. Comparative estimates revealing the efficiency of the proposed algorithms with respect to the known ones are given. In particular, a proposed method of calculating the 2r × 2r -point 2-D QDFT uses 18N2 less multiplications than the well-known column-row method and method of calculation based on the symplectic decomposition. The proposed algorithm is simple to apply and design, which makes it very practical in color image processing in the frequency domain.

  9. Silicon carbide pointing mirror and telescope for the Geostationary Imaging Fourier Transform Spectrometer (GIFTS)

    NASA Astrophysics Data System (ADS)

    Schwalm, Mark; Dibiase, Dan; Landry, Dave; Rider, Brian; Ugolini, Virginia

    2005-08-01

    SSG Precision Optronics, Inc. has delivered a silicon carbide (SiC) pointing mirror and telescope for NASA's Geostationary Imaging Fourier Transform Spectrometer (GIFTS) project. The 28 x 45 cm SiC pointing mirror is part of SSG's two-axis gimbaled mirror assembly that will provide object-space pointing and jitter control. The 24 cm aperture telescope is an off-axis afocal three mirror anastigmat that is the collection aperture for the GIFTS instrument. Silicon carbide was selected for the GIFTS pointing mirror and telescope in order to minimize weight, provide athermal optical performance from room temperature to 190 Kelvin, and maintain image quality and line-of-sight stability in the presence of partial or full solar loading (minimizing solar outages). Both subsystems were successfully designed, fabricated, and subjected to testing prior to being delivered to Utah State University's Space Dynamics Laboratory for integration. This paper describes the pointing mirror and telescope design and hardware results.

  10. A dynamically aligned, step scanning mechanism for an imaging Fourier transform spectrometer for astronomy

    NASA Astrophysics Data System (ADS)

    Landry, Jean-Thomas; Grandmont, Frédéric

    2006-06-01

    This paper presents an overview of a step scanning mechanism employing a flexure stage coupled with a dynamically aligned mirror used in the SpIOMM (Spectrometre Imageur de l'Observatoire du Mont Megantic) instrument, an Imaging Fourier Transform Spectrometer (IFTS) concept for ground based telescopes produced in collaboration with ABB and Universite Laval. This instrument can acquire spectra of variable resolutions up to R = λ/Δλ = 10 000 from the near UV to the near IR (350 nm to 900 nm). It is designed to fit the f/8 focus of the Mont Megantic (Quebec, Canada) 1.6m optical telescope. The innovative aspect of this instrument compared to other imaging spectrometers is the spatial coverage. The FOV covers spans of 12 arc minutes in diameter with a pixel sampling of 0.55 arc seconds. Hence spectra of more than a million scene elements are acquired at each measurement.

  11. A Visible, Spatially-Modulated Imaging Fourier Transform Spectrometer (SMIFTS) for Astronomical Applications

    NASA Astrophysics Data System (ADS)

    Rafert, J. B.; Holbert, E. T.; Rusk, E. T.; Durham, S. E.; Caudill, E.; Keating, D.; Newby, H.

    1992-12-01

    We have constructed several visible, Spatially-Modulated Imaging Fourier Transform Spectrometers (SMIFTS) for spatially resolved spectral imaging in the visible wavelength region based on work by several authors including Yoshihara and Kitade (1967), Okamoto et al. (1984), Barnes (1985) and Smith and Schempp (1991). Our spectrometers require no moving parts, are compact and enjoy a number of advantages over the other spectral data collection technologies. The unique combination of characteristics define an important niche for astronomical, remote sensing, and reconnaissance spectral data acquisition. Our SMIFTS simultaneously acquires hundreds or thousands of spectral bands for hundreds or thousands of spectral channesl. This type of sensor has been called a "hyperspectral" sensor to emphasize the major quantitative difference between this type of sensor and multispectral imagers which collect only a few spectral bands. The SMIFTS consists of input optics (a telescope), a field limiting aperture, a beamsplitter which divides the input beam into two paths, two mirrors which redirect the split beams through the same path, a collimating lens which forms the interferogram of the input aperture on the detector plane, and a cylindrical imaging lens. Thus on the detector array one axis contains spatial information and the other axis contains the spectral information for each point of the spatial axis. The result of this arrangement is that each row of the detector array contains the interferogram of the corresponding point on the aperture or slit. This slit can be fixed upon the target, or the slit can be scanned across the target to build up a second axis of spatial information resulting in a data set with four dimensions: two spatial, one spectral, and one temporal. We present sample data for both astronomical and remote sensing applications taken with the Malabar SMIFTS. Barnes, T.H. "Photodiode Array Fourier Transform Spectrometer with Improved Dynamic Range", Appl. Opt, 24, 3702, (1985)

  12. Functional imaging of hemodynamic stimulus response in the rat retina with ultrahigh-speed spectral / Fourier domain OCT

    NASA Astrophysics Data System (ADS)

    Choi, WooJhon; Baumann, Bernhard; Clermont, Allen C.; Feener, Edward P.; Boas, David A.; Fujimoto, James G.

    2013-03-01

    Measuring retinal hemodynamics in response to flicker stimulus is important for investigating pathophysiology in small animal models of diabetic retinopathy, because a reduction in the hyperemic response is thought to be one of the earliest changes in diabetic retinopathy. In this study, we investigated functional imaging of retinal hemodynamics in response to flicker stimulus in the rat retina using an ultrahigh speed spectral / Fourier domain OCT system at 840nm with an axial scan rate of 244kHz. At 244kHz the nominal axial velocity range that could be measured without phase wrapping was +/-37.7mm/s. Pulsatile total retinal arterial blood flow as a function of time was measured using an en face Doppler approach where a 200μm × 200μm area centered at the central retinal artery was repeatedly raster scanned at a volume acquisition rate of 55Hz. Three-dimensional capillary imaging was performed using speckle decorrelation which has minimal angle dependency compared to other angiography techniques based on OCT phase information. During OCT imaging, a flicker stimulus could be applied to the retina synchronously by inserting a dichroic mirror in the imaging interface. An acute transient increase in total retinal blood flow could be detected. At the capillary level, an increase in the degree of speckle decorrelation in capillary OCT angiography images could also be observed, which indicates an increase in the velocity of blood at the capillary level. This method promises to be useful for the investigation of small animal models of ocular diseases.

  13. The wide-field Fourier spectroscopic-imaging of the radiation heat from the object itself in the middle infrared region for the health monitoring

    NASA Astrophysics Data System (ADS)

    Qi, Wei; Takuma, Takashi; Inui, Asuka; Tsutsumi, Ryosuke; Yuzuriha, Takehiko; Kagiyama, Hiroyasu; Kojima, Daisuke; Nishiyama, Akira; Ishimaru, Ichirou

    2012-03-01

    We are aiming at the realization of the wide-field spectroscopic-imaging-sensor that is available for the health monitoring or the plant factory. Conventionally, the body temperature is measured by the thermography as a total intensity of the middle infrared radiation. We are trying to analyze the spectroscopic characteristics of the radiation heat from the human body in detail to measure the blood glucose or the moisture-retaining properties of the human skin. The proposed imaging-type 2-dimensional Fourier spectroscopy can measure the radiation heat from the object itself with the wide field of view and the wide wavelength-band. In this proposed method, we install the phase-shifter on the optical Fourier-transform-plane of the imaging optics to give the arbitrary phase-shift to the half flux of the object beams. Thus, the interferogram can be formed on the imaging plane in each bright point by the phase-shift interference-phenomena between the object beams that are emitted from the each corresponding bright point on the objective surface. In this report, we mention the feasibility results of the wide-field spectroscopic-imaging using the black body for the basic optical evaluation and the house plants for measuring the glucose distribution with the infrared camera(wavelength: 8?m-14?m).

  14. Optical design of a static LWIR Fourier-transform imaging spectrometer with high throughput

    NASA Astrophysics Data System (ADS)

    Wang, Hai-yang; Fu, Yan-peng; Zheng, Wei-jian; Liao, Ning-fang; Jin, Wei-qi

    2013-08-01

    A LWIR Fourier-transform imaging spectrometer based on the static Michelson interferometer with high throughput is presented. Advantages and disadvantages of some common structures of imaging spectrometer are analyzed. Some selection of optimum configurations for imaging spectrometer is proceeded. The interferogram is acquired over the whole field of the camera while the scene of interest scans the path difference range, and vignetting should be strongly limited while keeping the size of the interferometer as small as possible for manufacturability and practicability reasons. The key point is to put the entrance pupil of the imaging lens inside the interferometer. The design of optical system is proposed. The field of view(FOV) is 10°.The operating wavelength range is from 8 to 12μm, F number is 2 and the working temperature range is -20°C~40°C. Optical system with 100% cold shield efficiency is good adaptability to wide environment temperature change. The spectrometer system has low utilization of solar energy in the infrared band, so to ensure its transmittance, and it is necessary to use a small amount of lenses as possible, so here the method of the active electromechanical athermalisation just uses four lenses in the system. Modulation transfer function (MTF), aberrant and distortion etc of optical system are analyzed. The results show that an excellent performance and image performance are obtained despite the simple structure.

  15. Real-time three-dimensional Fourier-domain optical coherence tomography video image guided microsurgeries

    NASA Astrophysics Data System (ADS)

    Kang, Jin U.; Huang, Yong; Zhang, Kang; Ibrahim, Zuhaib; Cha, Jaepyeong; Lee, W. P. Andrew; Brandacher, Gerald; Gehlbach, Peter L.

    2012-08-01

    The authors describe the development of an ultrafast three-dimensional (3D) optical coherence tomography (OCT) imaging system that provides real-time intraoperative video images of the surgical site to assist surgeons during microsurgical procedures. This system is based on a full-range complex conjugate free Fourier-domain OCT (FD-OCT). The system was built in a CPU-GPU heterogeneous computing architecture capable of video OCT image processing. The system displays at a maximum speed of 10 volume/s for an image volume size of 160×80×1024 (X×Y×Z) pixels. We have used this system to visualize and guide two prototypical microsurgical maneuvers: microvascular anastomosis of the rat femoral artery and ultramicrovascular isolation of the retinal arterioles of the bovine retina. Our preliminary experiments using 3D-OCT-guided microvascular anastomosis showed optimal visualization of the rat femoral artery (diameter<0.8 mm), instruments, and suture material. Real-time intraoperative guidance helped facilitate precise suture placement due to optimized views of the vessel wall during anastomosis. Using the bovine retina as a model system, we have performed "ultra microvascular" feasibility studies by guiding handheld surgical micro-instruments to isolate retinal arterioles (diameter˜0.1 mm). Isolation of the microvessels was confirmed by successfully passing a suture beneath the vessel in the 3D imaging environment.

  16. Real-time three-dimensional Fourier-domain optical coherence tomography video image guided microsurgeries

    PubMed Central

    Huang, Yong; Zhang, Kang; Ibrahim, Zuhaib; Cha, Jaepyeong; Lee, W. P. Andrew; Brandacher, Gerald; Gehlbach, Peter L.

    2012-01-01

    Abstract. The authors describe the development of an ultrafast three-dimensional (3D) optical coherence tomography (OCT) imaging system that provides real-time intraoperative video images of the surgical site to assist surgeons during microsurgical procedures. This system is based on a full-range complex conjugate free Fourier-domain OCT (FD-OCT). The system was built in a CPU-GPU heterogeneous computing architecture capable of video OCT image processing. The system displays at a maximum speed of 10  volume/s for an image volume size of 160×80×1024 (X×Y×Z) pixels. We have used this system to visualize and guide two prototypical microsurgical maneuvers: microvascular anastomosis of the rat femoral artery and ultramicrovascular isolation of the retinal arterioles of the bovine retina. Our preliminary experiments using 3D-OCT-guided microvascular anastomosis showed optimal visualization of the rat femoral artery (diameter<0.8  mm), instruments, and suture material. Real-time intraoperative guidance helped facilitate precise suture placement due to optimized views of the vessel wall during anastomosis. Using the bovine retina as a model system, we have performed “ultra microvascular” feasibility studies by guiding handheld surgical micro-instruments to isolate retinal arterioles (diameter∼0.1  mm). Isolation of the microvessels was confirmed by successfully passing a suture beneath the vessel in the 3D imaging environment. PMID:23224164

  17. Real-time three-dimensional Fourier-domain optical coherence tomography video image guided microsurgeries.

    PubMed

    Kang, Jin U; Huang, Yong; Zhang, Kang; Ibrahim, Zuhaib; Cha, Jaepyeong; Lee, W P Andrew; Brandacher, Gerald; Gehlbach, Peter L

    2012-08-01

    The authors describe the development of an ultrafast three-dimensional (3D) optical coherence tomography (OCT) imaging system that provides real-time intraoperative video images of the surgical site to assist surgeons during microsurgical procedures. This system is based on a full-range complex conjugate free Fourier-domain OCT (FD-OCT). The system was built in a CPU-GPU heterogeneous computing architecture capable of video OCT image processing. The system displays at a maximum speed of 10 volume/s for an image volume size of 160 × 80 × 1024(X × Y × Z) pixels. We have used this system to visualize and guide two prototypical microsurgical maneuvers: microvascular anastomosis of the rat femoral artery and ultramicrovascular isolation of the retinal arterioles of the bovine retina. Our preliminary experiments using 3D-OCT-guided microvascular anastomosis showed optimal visualization of the rat femoral artery (diameter<0.8 mm), instruments, and suture material. Real-time intraoperative guidance helped facilitate precise suture placement due to optimized views of the vessel wall during anastomosis. Using the bovine retina as a model system, we have performed "ultra microvascular" feasibility studies by guiding handheld surgical micro-instruments to isolate retinal arterioles (diameter ~0.1 mm). Isolation of the microvessels was confirmed by successfully passing a suture beneath the vessel in the 3D imaging environment. PMID:23224164

  18. Hybrid-dual-fourier tomographic algorithm for a fast three-dimensionial optical image reconstruction in turbid media

    NASA Technical Reports Server (NTRS)

    Alfano, Robert R. (Inventor); Cai, Wei (Inventor)

    2007-01-01

    A reconstruction technique for reducing computation burden in the 3D image processes, wherein the reconstruction procedure comprises an inverse and a forward model. The inverse model uses a hybrid dual Fourier algorithm that combines a 2D Fourier inversion with a 1D matrix inversion to thereby provide high-speed inverse computations. The inverse algorithm uses a hybrid transfer to provide fast Fourier inversion for data of multiple sources and multiple detectors. The forward model is based on an analytical cumulant solution of a radiative transfer equation. The accurate analytical form of the solution to the radiative transfer equation provides an efficient formalism for fast computation of the forward model.

  19. Extended Field of View Soft X-Ray Fourier Transform Holography: Toward Imaging Ultrafast Evolution in a Single Shot

    SciTech Connect

    Schlotter, W.F.; Luening, J.; Rick, R.; Chen, K.; Scherz, A.; Eisebitt, S.; Guenther, C.M.; Eberhardt, W.; Hellwig, O.; Stohr, J.; /SLAC, SSRL

    2009-04-29

    Panoramic full-field imaging is demonstrated by applying spatial multiplexing to Fourier transform holography. Multiple object and reference waves extend the effective field of view for lensless imaging without compromising the spatial resolution. In this way, local regions of interest distributed throughout a sample can be simultaneously imaged with high spatial resolution. A method is proposed for capturing multiple ultrafast images of a sample with a single x-ray pulse.

  20. X-ray Phase Imaging Microscopy with Two-Dimensional Knife-Edge Filters

    NASA Astrophysics Data System (ADS)

    Choi, Jaeho; Park, Yong-Sung

    2012-04-01

    A novel scheme of X-ray differential phase imaging was implemented with an array source and a two-dimensional Foucault knife-edge (2DFK). A pinhole array lens was employed to manipulate the X-ray beam on the Fourier space. An emerging biaxial scanning procedure was also demonstrated with the periodic 2DFK. The differential phase images (DPIs) of the midrib in a leaf of a rose bush were visualized to verify the phase imaging of biological specimens by the proposed method. It also has features of depicting multiple-stack phase images, and rendering morphological DPIs, because it acquires pure phase information.

  1. PHASE CORRELATION METHOD FOR THE ALIGNMENT OF TOTAL SOLAR ECLIPSE IMAGES

    SciTech Connect

    Druckmueller, M.

    2009-12-01

    A modified phase correlation method, based on Fourier transform, which enables the alignment of solar coronal images taken during the total solar eclipses, is presented. The method enables the measurement of translation, rotation, and scaling factor between two images. With the application of this technique, pairs of images with different exposure times, different brightness scale, such as linear for CCD and nonlinear for images taken with photographic film, and even images from different emission lines can be aligned with sub-pixel precision.

  2. MEMS-Based Handheld Fourier Domain Doppler Optical Coherence Tomography for Intraoperative Microvascular Anastomosis Imaging

    PubMed Central

    Huang, Yong; Furtmüller, Georg J.; Tong, Dedi; Zhu, Shan; Lee, W. P. Andrew; Brandacher, Gerald; Kang, Jin U.

    2014-01-01

    Purpose To demonstrate the feasibility of a miniature handheld optical coherence tomography (OCT) imager for real time intraoperative vascular patency evaluation in the setting of super-microsurgical vessel anastomosis. Methods A novel handheld imager Fourier domain Doppler optical coherence tomography based on a 1.3-µm central wavelength swept source for extravascular imaging was developed. The imager was minimized through the adoption of a 2.4-mm diameter microelectromechanical systems (MEMS) scanning mirror, additionally a 12.7-mm diameter lens system was designed and combined with the MEMS mirror to achieve a small form factor that optimize functionality as a handheld extravascular OCT imager. To evaluate in-vivo applicability, super-microsurgical vessel anastomosis was performed in a mouse femoral vessel cut and repair model employing conventional interrupted suture technique as well as a novel non-suture cuff technique. Vascular anastomosis patency after clinically successful repair was evaluated using the novel handheld OCT imager. Results With an adjustable lateral image field of view up to 1.5 mm by 1.5 mm, high-resolution simultaneous structural and flow imaging of the blood vessels were successfully acquired for BALB/C mouse after orthotopic hind limb transplantation using a non-suture cuff technique and BALB/C mouse after femoral artery anastomosis using a suture technique. We experimentally quantify the axial and lateral resolution of the OCT to be 12.6 µm in air and 17.5 µm respectively. The OCT has a sensitivity of 84 dB and sensitivity roll-off of 5.7 dB/mm over an imaging range of 5 mm. Imaging with a frame rate of 36 Hz for an image size of 1000(lateral)×512(axial) pixels using a 50,000 A-lines per second swept source was achieved. Quantitative vessel lumen patency, lumen narrowing and thrombosis analysis were performed based on acquired structure and Doppler images. Conclusions A miniature handheld OCT imager that can be used for intraoperative evaluation of microvascular anastomosis was successfully demonstrated. PMID:25474742

  3. Fourier phase analysis on equilibrium gated radionuclide ventriculography: Range of phase spread and cut-off limits in normal individuals

    PubMed Central

    Ramaiah, Vijayaraghavan L; Harish, B; Sunil, HV; Selvakumar, Job; Ravi, Kishore AG; Nair, Gopinathan

    2011-01-01

    Aim: To define the range of phase spread on equilibrium gated radionuclide ventriculography (ERNV) in normal individuals and derive the cut-off limit for the parameters to detect cardiac dyssynchrony. Materials and Methods: ERNV was carried out in 30 individuals (age 53±23 years, 25 males and 5 females) who had no history of cardiovascular disease. They all had normal left ventricular ejection fraction (LVEF 55–70%) as determined by echocardiography, were in sinus rhythm, with normal QRS duration (≤120 msec) and normal coronary angiography. First harmonic phase analysis was performed on scintigraphic data acquired in best septal view. Left and right ventricular standard deviation (LVSD and RVSD, respectively) and interventricular mechanical delay (IVMD), the absolute difference of mean phase angles of right and left ventricle, were computed and expressed in milliseconds. Mean + 3 standard deviation (SD) was used to derive the cut-off limits. Results: Average LVEF and duration of cardiac cycle in the study group were 62.5%±5.44% and 868.9±114.5 msec, respectively. The observations of LVSD, RVSD and right and left ventricular mean phase angles were shown to be normally distributed by Shapiro–Wilk test. Cut-off limits for LVSD, RVSD and IVMD were calculated to be 80 msec, 85 msec and 75 msec, respectively. Conclusion: Fourier phase analysis on ERNV is an effective tool for the evaluation of synchronicity of cardiac contraction. The cut-off limits of parameters of dyssynchrony can be used to separate heart failure patients with cardiac dyssynchrony from those without. ERNV can be used to select patients for cardiac resynchronization therapy. PMID:23326063

  4. The New Physical Optics Notebook: Tutorials in Fourier Optics.

    ERIC Educational Resources Information Center

    Reynolds, George O.; And Others

    This is a textbook of Fourier optics for the classroom or self-study. Major topics included in the 38 chapters are: Huygens' principle and Fourier transforms; image formation; optical coherence theory; coherent imaging; image analysis; coherent noise; interferometry; holography; communication theory techniques; analog optical computing; phase

  5. Optical Conformational Transition Pathways of DsRed, Elucidated by Polarization-Modulated Fourier Imaging Correlation Spectroscopy

    NASA Astrophysics Data System (ADS)

    Marcus, Andrew; Senning, Eric; Lott, Geoffrey; Fink, Michael

    2009-03-01

    This work presents a novel `phase-selective' approach to fluorescence fluctuation spectroscopy that simultaneously determines the joint probability distributions and two-dimensional spectral densities of protein conformational transitions, and nanometer center-of-mass displacements. Fourier imaging correlation spectroscopy (FICS) combines polarization- and intensity-modulated photo-excitation with phase-sensitive signal detection to monitor the collective coordinate fluctuations from a large population of fluorescent molecules (N ˜ 106). FICS is based on the principle that fluctuations of partially averaged molecular coordinates can be monitored through variations of an optical signal phase. Experiments are performed on DsRed, a tetrameric complex of fluorescent protein subunits, derived from a reef-building coral. Thermally induced conformational transitions of the DsRed complex lead to fluctuations in the optical dipolar coupling between adjacent chromophore sites. An analysis of polarization-resolved FICS fluctuation data, in terms of two-dimensional spectra and joint probability distributions, provides detailed information about cooperative `transition pathways' between distinct dipole-coupled DsRed conformations.

  6. Second Harmonic Generation Imaging and Fourier Transform Spectral Analysis Reveal Damage in Fatigue-Loaded Tendons

    PubMed Central

    Fung, David T.; Sereysky, Jedd B.; Basta-Pljakic, Jelena; Laudier, Damien M.; Huq, Rumana; Jepsen, Karl J.; Schaffler, Mitchell B.; Flatow, Evan L.

    2016-01-01

    Conventional histologic methods provide valuable information regarding the physical nature of damage in fatigue-loaded tendons, limited to thin, two-dimensional sections. We introduce an imaging method that characterizes tendon microstructure three-dimensionally and develop quantitative, spatial measures of damage formation within tendons. Rat patellar tendons were fatigue loaded in vivo to low, moderate, and high damage levels. Tendon microstructure was characterized using multiphoton microscopy by capturing second harmonic generation signals. Image stacks were analyzed using Fourier transform-derived computations to assess frequency-based properties of damage. Results showed 3D microstructure with progressively increased density and variety of damage patterns, characterized by kinked deformations at low, fiber dissociation at moderate, and fiber thinning and out-of-plane discontinuities at high damage levels. Image analysis generated radial distributions of power spectral gradients, establishing a “fingerprint” of tendon damage. Additionally, matrix damage was mapped using local, discretized orientation vectors. The frequency distribution of vector angles, a measure of damage content, differed from one damage level to the next. This study established an objective 3D imaging and analysis method for tendon microstructure, which characterizes directionality and anisotropy of the tendon microstructure and quantitative measures of damage that will advance investigations of the microstructural basis of degradation that precedes overuse injuries. PMID:20232150

  7. Image reconstruction from partial pseudo polar Fourier sampling based on alternating direction total variation minimization

    NASA Astrophysics Data System (ADS)

    Liu, Qiu-hong; Shu, Fan; Zhang, Wen-kun; Cai, Ai-long; Li, Lei; Yan, Bin

    2013-08-01

    Linear scan Computed Tomography (LCT) has emerged as a promising technique in fields like industrial scanning and security inspection due to its straight-line source trajectory and high scanning speed. However, in practical applications of LCT, the ordinary algorithms suffer from serious artifacts owing to the limited-angle and insufficient data. In this paper, a new method which reconstructs image from partial Fourier data sampled in pseudo polar grid based on alternating direction anisometric total variation minimization has been proposed. The main idea is to reform the image reconstruction problem into solving an under-determined linear equation, and then reconstruct image by applying the popular total variation (TV) minimization to reform an unconstraint optimization by means of augmented Lagrange method and using the alternating minimization method of multiplier (ADMM) which contributes to the fast convergence. The proposed method is practical in the large-scale task of reconstruction due to its algorithmic simplicity and computational efficiency and reconstructs better images. The results of the numerical simulations and pseudo real data reconstructions from the linear scan validate that the proposed method is both efficient and accurate.

  8. Deep-subwavelength Nanometric Image Reconstruction using Fourier Domain Optical Normalization

    PubMed Central

    Qin, Jing; Silver, Richard M.; Barnes, Bryan M.; Zhou, Hui; Dixson, Ronald G.; Henn, Mark-Alexander

    2016-01-01

    Quantitative optical measurements of deep sub-wavelength, three-dimensional, nanometric structures with sensitivity to sub-nanometer details address an ubiquitous measurement challenge. A Fourier domain normalization approach is used in the Fourier optical imaging code to simulate the full three-dimensional scattered light field of nominally 15 nm sized structures, accurately replicating the light field as a function of the focus position. Using the full three-dimensional light field, nanometer scale details such as a 2 nm thin conformal oxide and nanometer topography are rigorously fitted for features less than 1/30th of the wavelength in size. The densely packed structures are positioned nearly an order of magnitude closer than the conventional Rayleigh resolution limit and can be measured with sub-nanometer parametric uncertainties. This approach enables a practical measurement sensitivity to size variations of only a few atoms in size using a high throughput optical configuration with broad application in measuring nanometric structures and nanoelectronic devices. PMID:26925297

  9. INTERFACE OF A REVERSE-PHASE HIGH-PERFORMANCE LIQUID CHROMATOGRAPH WITH A DIFFUSE REFLECTANCE FOURIER TRANSFORM INFRARED SPECTROMETER

    EPA Science Inventory

    An approach to the interface of a reverse-phase high-performance liquid chromatograph and a Fourier transform infrared spectrometer has been developed in which the solutes eluting from the column are continuously extracted into dichloromethane. The application of both flow cell a...

  10. An effective approach for iris recognition using phase-based image matching.

    PubMed

    Miyazawa, Kazuyuki; Ito, Koichi; Aoki, Takafumi; Kobayashi, Koji; Nakajima, Hiroshi

    2008-10-01

    This paper presents an efficient algorithm for iris recognition using phase-based image matching--an image matching technique using phase components in 2D Discrete Fourier Transforms (DFTs) of given images. Experimental evaluation using CASIA iris image databases (versions 1.0 and 2.0) and Iris Challenge Evaluation (ICE) 2005 database clearly demonstrates that the use of phase components of iris images makes possible to achieve highly accurate iris recognition with a simple matching algorithm. This paper also discusses major implementation issues of our algorithm. In order to reduce the size of iris data and to prevent the visibility of iris images, we introduce the idea of 2D Fourier Phase Code (FPC) for representing iris information. The 2D FPC is particularly useful for implementing compact iris recognition devices using state-of-the-art Digital Signal Processing (DSP) technology. PMID:18703828

  11. Directional absorption by phased arrays of plasmonic nanoantennae probed with time-reversed Fourier microscopy

    NASA Astrophysics Data System (ADS)

    Lozano, Gabriel; Barten, Tommy; Grzela, Grzegorz; Gómez Rivas, Jaime

    2014-01-01

    We demonstrate that an ordered array of aluminum nanopyramids, behaving as a phased array of optical antennae, strongly modifies light absorption in thin layers of dye molecules. Photoluminescence measurements as a function of the illumination angle are performed using a time-reversed Fourier microscope. This technique enables a variable-angle plane-wave illumination of nanostructures in a microscope-based setup. Our measurements reveal an enhancement of the light conversion in certain directions of illumination, which indicate the efficient diffractive coupling between the free space radiation and the surface plasmons. Numerical simulations confirm that surface modes supported by the periodic array enhance the intensity of the pump field in the space between particles, where the dye molecules are located, yielding a directional plasmonic-mediated enhancement of the optical absorption. This combined experimental and numerical characterization of the angular dependence of light absorption in nanostructures can be beneficial for the design and optimization of devices in which the harvesting of light plays a major role.

  12. Defining photon channels in strong-field physics: the photon-phase Fourier representation

    NASA Astrophysics Data System (ADS)

    Zeng, Shuo; Zohrabi, Mohammad; Berry, Ben; Ablikim, Utuq; Kling, Nora; Severt, Travis; Jochim, Bethany; Carnes, Kevin; Ben-Itzhak, Itzik; Esry, Brett

    2014-05-01

    In strong-field physics, complex atomic and molecular dynamics can be steered by the carrier-envelope phase (CEP). The general theory formulated in Refs., provides a rigorous foundation upon which this understanding might be built. By recognizing the underlying periodicity of the time-dependent Schrödinger equation--and thus its solutions--in the CEP, all CEP effects can be understood as the interference of different photon channels. We will show that this understanding can be turned around to extract information on the photon channel by examining the CEP dependence. In particular, by taking the Fourier transform with respect to the CEP, photon channel information can be extracted from both theory and experiment. Through several examples, we will also show that this technique can be applied to any system and provides knowledge of the net numbers of photons absorbed--even in few-cycle pulses--that is not available in any other way. This work was supported by the Chemical Sciences, Geosciences, and Biosciences Division, Office of Basic Energy Sciences, Office of Science, U.S. Department of Energy under Grant No. DE-FG02-86ER13491. The PULSAR laser was provided by Grant No. DE-FG02-09.

  13. Lipid domains and orthorhombic phases in model stratum corneum: evidence from Fourier transform infrared spectroscopy studies.

    PubMed

    Moore, D J; Rerek, M E; Mendelsohn, R

    1997-02-24

    A three component model for the lipid barrier of the stratum corneum (SC) consisting of ceramide III, cholesterol, and perdeuterated palmitic acid, has been characterized by Fourier transform infrared spectroscopy. At physiological temperature the CD2 scissoring mode of the palmitic acid methylenes, and the CH2 rocking mode of the ceramide methylenes, are each split into two components. This indicates that both components exist in separate, conformationally ordered phases, probably with orthorhombic perpendicular subcells. The magnitude of the splitting indicates that the domains are at least 100 chains in size. The thermotropic behavior of the CD2 stretching vibrations demonstrates that conformational disordering of the palmitic acid commences at 42 degrees C with a transition midpoint of 50 degrees C. The CH2 stretching frequency indicates the ceramide chains remain ordered until 50 degrees C then disorder with a midpoint of 67 degrees C. The results provide a molecular characterization for the complex low temperature (10-40 degrees C) dynamic behavior suggested by recent 2H NMR experiments. PMID:9070896

  14. Measurement of the mid-infrared Fourier spectroscopic imaging of whole human face by portable apparatus (size: 50*50 mm, weight: 200 g)

    NASA Astrophysics Data System (ADS)

    Qi, Wei; Suzuki, Yo; Fujiwara, Masaru; Saito, Tsubasa; Suzuki, Satoru; Abeygunawardhana, Pradeep K.; Wada, Kenji; Nishiyama, Akira; Ishimaru, Ichiro

    2014-11-01

    In the daily living space, measurement of the biological-substance distributions such as sebum can be realized by the proposed method of imaging-type 2-dimensional Fourier spectroscopy. This method has the strong robustness for mechanical vibrations. So, the spectrometer (size: 50*50mm, weight: 200g) can be produced without anti-vibration mechanism. Moreover, the phase shifter is a core part of the spectrometer, and it is constructed by the low-price bimorph type actuator which is depending on the vibration control of the piezoceramic in proposed method. It is appropriate as the actuator of the phase shifter from the evaluation results of the actuator straightness and position accuracy in the midinfrared region. As we know, the Fourier spectroscopy has a high light utilization efficiency. Therefore, the low price microbolometer can be used as the imaging sensor. So, the low-price (10,000 U.S. dollars), compact and high portability spectrometer can be produced. Furthermore, the much higher position accuracy in the short wavelength region is requested as we know, the phase shift correction method has been proposed. In this paper, high performance evaluations of the portable spectroscopy apparatus have been discussed by using the CO2 laser spectroscopy results in the midinfrared region. Then, the phase shift correction method was explained. At the end, we demonstrated the feasibility of the mid-infrared imaging of whole human faces without active illuminations.

  15. Long-distance super-resolution imaging assisted by enhanced spatial Fourier transform.

    PubMed

    Tang, Heng-He; Liu, Pu-Kun

    2015-09-01

    A new gradient-index (GRIN) lens that can realize enhanced spatial Fourier transform (FT) over optically long distances is demonstrated. By using an anisotropic GRIN metamaterial with hyperbolic dispersion, evanescent wave in free space can be transformed into propagating wave in the metamaterial and then focused outside due to negative-refraction. Both the results based on the ray tracing and the finite element simulation show that the spatial frequency bandwidth of the spatial FT can be extended to 2.7k(0) (k(0) is the wave vector in free space). Furthermore, assisted by the enhanced spatial FT, a new long-distance (in the optical far-field region) super-resolution imaging scheme is also proposed and the super resolved capability of λ/5 (λ is the wavelength in free space) is verified. The work may provide technical support for designing new-type high-speed microscopes with long working distances. PMID:26368459

  16. The use of the fractional Fourier transform with coded excitation in ultrasound imaging.

    PubMed

    Bennett, Michael J; McLaughlin, Steve; Anderson, Tom; McDicken, Norman

    2006-04-01

    Medical ultrasound systems are limited by a tradeoff between axial resolution and the maximum imaging depth which may be achieved. The technique of coded excitation has been used extensively in the field of RADAR and SONAR for some time, but has only relatively recently been exploited in the area of medical ultrasound. This technique is attractive because allows the relationship between the pulse length and the maximum achievable spatial resolution to be changed. The work presented here explores the possibility of using the fractional Fourier transform as an effective means for the processing of signals received after the transmission of linear frequency modulated chirps. Results are presented which demonstrate that this technique is able to offer spatial resolutions similar to those obtained with a single cycle duration signal. PMID:16602583

  17. Science results from the imaging Fourier transform spectrometer SpIOMM

    NASA Astrophysics Data System (ADS)

    Drissen, L.; Bernier, A.-P.; Charlebois, M.; Brière, É.; Robert, C.; Joncas, G.; Martin, P.; Grandmont, F.

    2008-07-01

    SpIOMM is an imaging Fourier transform spectrometer designed to obtain the visible range (350 - 850 nm) spectrum of every light source in a circular field of view of 12 arcminutes in diameter. Attached to the 1.6-m telescope of the Observatoire du Mont Megantic in southern Quebec. We present here some results of three successful observing runs in 2007, which highlight SpIOMM's capabilities to map emission line objects over a very wide field of view and a broad spectral range. In particular, we discuss data cubes from the planetary nebula M27, the supernova remnants NGC 6992 and M1, the barred spiral galaxy NGC7479, as well as Stephan's quintet, and interacting group of galaxies.

  18. New scientific results with SpIOMM: a testbed for CFHT's imaging Fourier transform spectrometer SITELLE

    NASA Astrophysics Data System (ADS)

    Drissen, L.; Alarie, A.; Martin, T.; Lagrois, D.; Rousseau-Nepton, L.; Bilodeau, A.; Robert, C.; Joncas, G.; Iglesias-Páramo, J.

    2012-09-01

    We present new data obtained with SpIOMM, the imaging Fourier transform spectrometer attached to the 1.6-m telescope of the Observatoire du Mont-Megantic in Québec. Recent technical and data reduction improvements have significantly increased SpIOMM's capabilities to observe fainter objects or weaker nebular lines, as well as continuum sources and absorption lines, and to increase its modulation efficiency in the near ultraviolet. To illustrate these improvements, we present data on the supernova remnant Cas A, planetary nebulae M27 and M97, the Wolf-Rayet ring nebula M1-67, spiral galaxies M63 and NGC 3344, as well as the interacting pair of galaxies Arp 84.

  19. A Fourier-based compressed sensing technique for accelerated CT image reconstruction using first-order methods

    NASA Astrophysics Data System (ADS)

    Choi, Kihwan; Li, Ruijiang; Nam, Haewon; Xing, Lei

    2014-06-01

    As a solution to iterative CT image reconstruction, first-order methods are prominent for the large-scale capability and the fast convergence rate {O}(1/k^2). In practice, the CT system matrix with a large condition number may lead to slow convergence speed despite the theoretically promising upper bound. The aim of this study is to develop a Fourier-based scaling technique to enhance the convergence speed of first-order methods applied to CT image reconstruction. Instead of working in the projection domain, we transform the projection data and construct a data fidelity model in Fourier space. Inspired by the filtered backprojection formalism, the data are appropriately weighted in Fourier space. We formulate an optimization problem based on weighted least-squares in the Fourier space and total-variation (TV) regularization in image space for parallel-beam, fan-beam and cone-beam CT geometry. To achieve the maximum computational speed, the optimization problem is solved using a fast iterative shrinkage-thresholding algorithm with backtracking line search and GPU implementation of projection/backprojection. The performance of the proposed algorithm is demonstrated through a series of digital simulation and experimental phantom studies. The results are compared with the existing TV regularized techniques based on statistics-based weighted least-squares as well as basic algebraic reconstruction technique. The proposed Fourier-based compressed sensing (CS) method significantly improves both the image quality and the convergence rate compared to the existing CS techniques.

  20. Imaging phased telescope array study

    NASA Technical Reports Server (NTRS)

    Harvey, James E.

    1989-01-01

    The problems encountered in obtaining a wide field-of-view with large, space-based direct imaging phased telescope arrays were considered. After defining some of the critical systems issues, previous relevant work in the literature was reviewed and summarized. An extensive list was made of potential error sources and the error sources were categorized in the form of an error budget tree including optical design errors, optical fabrication errors, assembly and alignment errors, and environmental errors. After choosing a top level image quality requirment as a goal, a preliminary tops-down error budget allocation was performed; then, based upon engineering experience, detailed analysis, or data from the literature, a bottoms-up error budget reallocation was performed in an attempt to achieve an equitable distribution of difficulty in satisfying the various allocations. This exercise provided a realistic allocation for residual off-axis optical design errors in the presence of state-of-the-art optical fabrication and alignment errors. Three different computational techniques were developed for computing the image degradation of phased telescope arrays due to aberrations of the individual telescopes. Parametric studies and sensitivity analyses were then performed for a variety of subaperture configurations and telescope design parameters in an attempt to determine how the off-axis performance of a phased telescope array varies as the telescopes are scaled up in size. The Air Force Weapons Laboratory (AFWL) multipurpose telescope testbed (MMTT) configuration was analyzed in detail with regard to image degradation due to field curvature and distortion of the individual telescopes as they are scaled up in size.

  1. An anti-noise subpixel algorithm based on phase-shifting of Fourier transform and its application in CCD photoelectric autocollimator

    NASA Astrophysics Data System (ADS)

    Gao, Min; Bian, Zhenglan; Dong, Zuoren; Ye, Qing; Fang, Zujie; Qu, Ronghui

    2010-11-01

    An anti-noise subpixel algorithm of phase-shifting of fundamental frequency was presented based on the phase-shifting of Fourier transform and the anti-noise characteristics of low-frequency part of the phase spectrum of the image. The essence of the algorithm is that the displacement caculation of the image is replaced by the movement caculation of the coordinate, which makes the phase of the fundamental frequency zero under different coordninates when image position changes. Under the circumstances that the image of the CCD autocollimator is polluted by the noises caused by tempreture, the measuring accuracies of the normally-used barycenter, edge detection, Gaussian fitting algorithm and the algorithm presented in this paper were compared. Experiment results show, the subpixel algorithm demonstrated here has the advantages of strong anti-noise ability and high precision. The reliability of the algorithm is also disproved by the peak location of the reconstructed image after the removal of higher harmonics. When applied to the one-dimensional CCD photoelectric autocaollimator used in field conditions, fine linearity and +/-3// measurement accuracy were simutaneously obtained in the whole +/-3600// measurement range when the temperature varies between -400C-600C.

  2. Localization of polyhydroxybutyrate in sugarcane using Fourier-transform infrared microspectroscopy and multivariate imaging

    DOE PAGESBeta

    Lupoi, Jason S.; Smith-Moritz, Andreia; Singh, Seema; McQualter, Richard; Scheller, Henrik V.; Simmons, Blake A.; Henry, Robert J.

    2015-07-10

    Background: Slow-degrading, fossil fuel-derived plastics can have deleterious effects on the environment, especially marine ecosystems. The production of bio-based, biodegradable plastics from or in plants can assist in supplanting those manufactured using fossil fuels. Polyhydroxybutyrate (PHB) is one such biodegradable polyester that has been evaluated as a possible candidate for relinquishing the use of environmentally harmful plastics. Results: PHB, possessing similar properties to polyesters produced from non-renewable sources, has been previously engineered in sugarcane, thereby creating a high-value co-product in addition to the high biomass yield. This manuscript illustrates the coupling of a Fourier-transform infrared microspectrometer, equipped with a focalmore » plane array (FPA) detector, with multivariate imaging to successfully identify and localize PHB aggregates. Principal component analysis imaging facilitated the mining of the abundant quantity of spectral data acquired using the FPA for distinct PHB vibrational modes. PHB was measured in the chloroplasts of mesophyll and bundle sheath cells, acquiescent with previously evaluated plant samples. Conclusion: This study demonstrates the power of IR microspectroscopy to rapidly image plant sections to provide a snapshot of the chemical composition of the cell. While PHB was localized in sugarcane, this method is readily transferable to other value-added co-products in different plants.« less

  3. 3D imaging of dental hard tissues with Fourier domain optical coherence tomography

    NASA Astrophysics Data System (ADS)

    Chen, Yueli L.; Yang, Yi; Ma, Jing; Yan, Jun; Shou, Yuanxin; Wang, Tianheng; Ramesh, Aruna; Zhao, Jing; Zhu, Quing

    2011-03-01

    A fiber optical coherence tomography (OCT) probe is used for three dimensional dental imaging. The probe has a lightweight miniaturized design with a size of a pen to facilitate clinic in vivo diagnostics. The probe is interfaced with a swept-source / Fourier domain optical coherence tomography at 20K axial scanning rate. The tooth samples were scanned from occlusal, buccal, lingual, mesial, and distal orientations. Three dimensional imaging covers tooth surface area up to 10 mm x 10 mm with a depth about 5 mm, where a majority of caries affection occurs. OCT image provides better resolution and contrast compared to gold standard dental radiography (X-ray). In particular, the technology is well suited for occlusal caries detection. This is complementary to X-ray as occlusal caries affection is difficult to be detected due to the X-ray projectile scan geometry. The 3D topology of occlusal surface as well as the dentin-enamel junction (DEJ) surface inside the tooth can be visualized. The lesion area appears with much stronger back scattering signal intensity.

  4. The Wavenumber Algorithm: Fast Fourier-Domain Imaging Using Full Matrix Capture

    NASA Astrophysics Data System (ADS)

    Hunter, A. J.; Drinkwater, B. W.; Wilcox, P. D.

    2009-03-01

    We develop a Fourier-domain approach to full matrix imaging based on the wavenumber algorithm used in synthetic aperture radar and sonar. The extension to the wavenumber algorithm for full matrix capture is described and the performance of the new algorithm is compared to the total focusing method (TFM), which we use as a representative benchmark for the time-domain algorithms. The wavenumber algorithm provides a mathematically rigorous solution to the inverse problem for the assumed forward wave propagation model, whereas the TFM employs heuristic delay-and-sum beamforming. Consequently, the wavenumber algorithm has an improved point-spread function and provides better imagery. However, the major advantage of the wavenumber algorithm is its superior computational performance. For large arrays and images, the wavenumber algorithm is several orders of magnitude faster than the TFM. On the other hand, the key advantage of the TFM is its flexibility. The wavenumber algorithm requires a regularly sampled linear array, while the TFM can handle arbitrary imaging geometries. The TFM and the wavenumber algorithm are compared using simulated and experimental data.

  5. Research on methods of spectral calibration and radiometric calibration of the windowing Fourier transform imaging spectrometer

    NASA Astrophysics Data System (ADS)

    Zhang, Lei; Gao, Jiao Bo; Zhao, Yu Jie; Luo, Yan Ling; Xiao, Xiang Guo; Zhang, Fang

    2013-08-01

    Spectral calibration and radiometric calibration is an important part in the data processing of the windowing Fourier transform imaging spectrometer, it can ensure that the spectral curve output from spectrometer are more closely to target spectrum. The main idea of spectral calibration is using a monochromatic source whose wavelength is known, in the same way, radiometric calibration can be achieved by using radiation source whose radiation characteristic is known. In this paper, we propose a set of methods of spectral calibration and radiometric calibration. In order to carry out spectral calibration, we use monocharomator to scan several sample points near the position of every spectral channel of imaging spectrometer, and then we employ Gaussian fitting function to determine the central wavelength and bandwidth of every spectral channel. In order to carry out radiometric calibration, we employ panchromatic light source and integrating sphere, at the position of every spectral channel of imaging spectrometer, we measure the response ability of spectrometer to radiation. The calibration accuracy is carefully analyzed. Experimental results show that calibration accuracy meet the given requirements.

  6. Localization of polyhydroxybutyrate in sugarcane using Fourier-transform infrared microspectroscopy and multivariate imaging

    SciTech Connect

    Lupoi, Jason S.; Smith-Moritz, Andreia; Singh, Seema; McQualter, Richard; Scheller, Henrik V.; Simmons, Blake A.; Henry, Robert J.

    2015-07-10

    Background: Slow-degrading, fossil fuel-derived plastics can have deleterious effects on the environment, especially marine ecosystems. The production of bio-based, biodegradable plastics from or in plants can assist in supplanting those manufactured using fossil fuels. Polyhydroxybutyrate (PHB) is one such biodegradable polyester that has been evaluated as a possible candidate for relinquishing the use of environmentally harmful plastics. Results: PHB, possessing similar properties to polyesters produced from non-renewable sources, has been previously engineered in sugarcane, thereby creating a high-value co-product in addition to the high biomass yield. This manuscript illustrates the coupling of a Fourier-transform infrared microspectrometer, equipped with a focal plane array (FPA) detector, with multivariate imaging to successfully identify and localize PHB aggregates. Principal component analysis imaging facilitated the mining of the abundant quantity of spectral data acquired using the FPA for distinct PHB vibrational modes. PHB was measured in the chloroplasts of mesophyll and bundle sheath cells, acquiescent with previously evaluated plant samples. Conclusion: This study demonstrates the power of IR microspectroscopy to rapidly image plant sections to provide a snapshot of the chemical composition of the cell. While PHB was localized in sugarcane, this method is readily transferable to other value-added co-products in different plants.

  7. Discrimination of healthy and osteoarthritic articular cartilage by Fourier transform infrared imaging and Fisher's discriminant analysis.

    PubMed

    Mao, Zhi-Hua; Yin, Jian-Hua; Zhang, Xue-Xi; Wang, Xiao; Xia, Yang

    2016-02-01

    Fourier transform infrared spectroscopic imaging (FTIRI) technique can be used to obtain the quantitative information of content and spatial distribution of principal components in cartilage by combining with chemometrics methods. In this study, FTIRI combining with principal component analysis (PCA) and Fisher's discriminant analysis (FDA) was applied to identify the healthy and osteoarthritic (OA) articular cartilage samples. Ten 10-μm thick sections of canine cartilages were imaged at 6.25μm/pixel in FTIRI. The infrared spectra extracted from the FTIR images were imported into SPSS software for PCA and FDA. Based on the PCA result of 2 principal components, the healthy and OA cartilage samples were effectively discriminated by the FDA with high accuracy of 94% for the initial samples (training set) and cross validation, as well as 86.67% for the prediction group. The study showed that cartilage degeneration became gradually weak with the increase of the depth. FTIRI combined with chemometrics may become an effective method for distinguishing healthy and OA cartilages in future. PMID:26977354

  8. FOURIER COMPONENT IMAGING OF WATER RESONANCE IN HUMAN BREAST PROVIDES MARKERS FOR MALIGNANCY

    PubMed Central

    Medved, Milica; Newstead, Gillian M.; Fan, Xiaobing; Du, Yiping P.; Olopade, Olufunmilayo I.; Shimauchi, Akiko; Zamora, Marta A.; Karczmar, Gregory S.

    2010-01-01

    Purpose To demonstrate that voxels with inhomogeneously broadened water resonances, as revealed by high spectral and spatial resolution (HiSS) MRI, correlate with underlying tumor pathology findings, and thus carry diagnostically useful information. Materials and Methods Thirty four women with mammographically suspicious breast lesions were imaged at 1.5 T, using high resolution echo-planar spectroscopic imaging. Fourier component images (FCIs) of off-peak spectral signal were generated, and clusters of voxels with significant inhomogeneous broadening (broadened clusters) were identified and correlated to biopsy results. Results Inhomogeneously broadened clusters were found significantly more frequently in malignant than in benign lesions. A larger percentage of broadened cluster voxels were found inside the malignant vs. benign lesions. The high statistical significance for separation of benign and malignant lesions was robust over a large range of postprocessing parameters, with a maximum ROC area under curve of 0.83. Conclusion In human breast, an inhomogeneously broadened water resonance can serve as a correlate marker for malignancy, and is likely to reflect underlying anatomy or physiology. PMID:19741276

  9. Fast Imaging Detector Readout Circuits with In-Pixel ADCs for Fourier Transform Imaging Spectrometers

    NASA Technical Reports Server (NTRS)

    Rider, D.; Blavier, J-F.; Cunningham, T.; Hancock, B.; Key, R.; Pannell, Z.; Sander, S.; Seshadri, S.; Sun, C.; Wrigley, C.

    2011-01-01

    Focal plane arrays (FPAs) with high frame rates and many pixels benefit several upcoming Earth science missions including GEO-CAPE, GACM, and ACE by enabling broader spatial coverage and higher spectral resolution. FPAs for the PanFTS, a high spatial resolution Fourier transform spectrometer and a candidate instrument for the GEO-CAPE mission are the focus of the developments reported here, but this FPA technology has the potential to enable a variety of future measurements and instruments. The ESTO ACT Program funded the developed of a fast readout integrated circuit (ROIC) based on an innovative in-pixel analog-to-digital converter (ADC). The 128 X 128 pixel ROIC features 60 ?m pixels, a 14-bit ADC in each pixel and operates at a continuous frame rate of 14 kHz consuming only 1.1 W of power. The ROIC outputs digitized data completely eliminating the bulky, power consuming signal chains needed by conventional FPAs. The 128 X 128 pixel ROIC has been fabricated in CMOS and tested at the Jet Propulsion Laboratory. The current version is designed to be hybridized with PIN photodiode arrays via indium bump bonding for light detection in the visible and ultraviolet spectral regions. However, the ROIC design incorporates a small photodiode in each cell to permit detailed characterization of the ROICperformance without the need for hybridization. We will describe the essential features of the ROIC design and present results of ROIC performance measurements.

  10. Proposal of AAA-battery-size one-shot ATR Fourier spectroscopic imager for on-site analysis: Simultaneous measurement of multi-components with high accuracy

    NASA Astrophysics Data System (ADS)

    Hosono, Satsuki; Qi, Wei; Sato, Shun; Suzuki, Yo; Fujiwara, Masaru; Hiramatsu, Hiroyuki; Suzuki, Satoru; Abeygunawardhana, P. K. W.; Wada, Kenji; Nishiyama, Akira; Ishimaru, Ichiro

    2015-03-01

    For simultaneous measurement of multi-components on-site like factories, the ultra-compact (diameter: 9[mm], length: 45[mm], weight: 200[g]) one-shot ATR (Attenuated Total Reflection) Fourier spectroscopic imager was proposed. Because the proposed one-shot Fourier spectroscopic imaging is based on spatial-phase-shift interferometer, interferograms could be obtained with simple optical configurations. We introduced the transmission-type relativeinclined phase-shifter, that was constructed with a cuboid prism and a wedge prism, onto the optical Fourier transform plane of infinity corrected optical systems. And also, small light-sources and cameras in the mid-infrared light region, whose size are several millimeter on a side, are essential components for the ultra-compact spectroscopic configuration. We selected the Graphite light source (light source area: 1.7×1.7[mm], maker: Hawkeye technologies) whose radiation factor was high. Fortunately, in these days we could apply the cost-effective 2-dimensional light receiving device for smartphone (e.g. product name: LEPTON, maker: FLIR, price: around 400USD). In the case of alcoholic drinks factory, conventionally workers measure glucose and ethanol concentrations by bringing liquid solution back to laboratories every day. The high portable spectroscopy will make it possible to measure multi-components simultaneously on manufacturing scene. But we found experimentally that absorption spectrum of glucose and water and ethanol were overlapped each other in near infrared light region. But for mid-infrared light region, we could distinguish specific absorption peaks of glucose (@10.5[μm]) and ethanol (@11.5[μm]) independently from water absorption. We obtained standard curve between absorption (@9.6[μm]) and ethanol concentration with high correlation coefficient 0.98 successfully by ATR imaging-type 2-dimensional Fourier spectroscopy (wavelength resolution: 0.057[μm]) with the graphite light source (maker: Hawkeye technologies, type: IR-75).

  11. The Depth-dependent Anisotropy of Articular Cartilage by Fourier-Transform Infrared Imaging (FTIRI)

    PubMed Central

    Xia, Yang; Ramakrishnan, Nagarajan; Bidthanapally, Aruna

    2007-01-01

    Objective: To study the anisotropic characteristics of individual histological zones in articular cartilage using Fourier Transform Infrared Imaging (FTIRI) at 6.25 μm pixel resolution. Method: A canine humeral cartilage-bone block was paraffin-embedded and microtomed into 6μm sections. Each of the five sections was infrared-imaged twenty-six times with identical acquisition parameters, for a 5° - 10° increment of a wire grid polarizer introduced before the detector in 0° - 180° angular space. Following the infrared imaging experiments, the same tissue sections were also imaged in a Polarized Light Microscope (PLM). Results: The infrared absorption components of cartilage (amide I, amide II, amide III, and sugar) exhibit distinctly different anisotropies, which vary differently as a function of the tissue depth. A new type of image, “the absorbance anisotropy map”, was constructed for each major component, which shows that, (1) the absorbance of the amide components in most parts of the tissue is anisotropic, (2) the anisotropic behavior in the radial and the superficial zones of the tissue are opposite, (3) the absorption profile of amide I is inverse to those of amide II and amide III, and (4) the infrared absorption of the sugar component is almost isotropic. The anisotropic variations of the amide components were fitted to an empirical equation. Conclusions: The infrared anisotropy map is a powerful tool to monitor the individual chemical components in articular cartilage. The ability to examine the same tissue section using both FTIRI and PLM offers the possibility of correlating the tissue's morphology with chemical distribution. PMID:17317225

  12. Virtual phase imager for Galileo

    NASA Technical Reports Server (NTRS)

    Janesick, J. R.; Hynecek, J.; Blouke, M. M.

    1981-01-01

    A CCD imaging array with a new virtual-phase technology that has been developed for use in a slow-scan imaging system for NASA's Galileo mission to Jupiter is described. Among its features are an absence of interlevel shorts, simplicity of fabrication, low dark current (less than 0.4 nA/sq cm), high full well, high quantum efficiency in the front side illumination mode, large dynamic range (greater than 5000), good charge transfer efficiency (0.99997), excellent linearity (0.2%), uniform pixel response (1%), and improved radiation hardness. It is noted that its operating voltages must be constrained to narrow windows to maintain good charge transfer efficiency and avoid the production of spurious and leakage charge.

  13. Correction for Eddy Current-Induced Echo-Shifting Effect in Partial-Fourier Diffusion Tensor Imaging

    PubMed Central

    Truong, Trong-Kha; Song, Allen W.; Chen, Nan-kuei

    2015-01-01

    In most diffusion tensor imaging (DTI) studies, images are acquired with either a partial-Fourier or a parallel partial-Fourier echo-planar imaging (EPI) sequence, in order to shorten the echo time and increase the signal-to-noise ratio (SNR). However, eddy currents induced by the diffusion-sensitizing gradients can often lead to a shift of the echo in k-space, resulting in three distinct types of artifacts in partial-Fourier DTI. Here, we present an improved DTI acquisition and reconstruction scheme, capable of generating high-quality and high-SNR DTI data without eddy current-induced artifacts. This new scheme consists of three components, respectively, addressing the three distinct types of artifacts. First, a k-space energy-anchored DTI sequence is designed to recover eddy current-induced signal loss (i.e., Type 1 artifact). Second, a multischeme partial-Fourier reconstruction is used to eliminate artificial signal elevation (i.e., Type 2 artifact) associated with the conventional partial-Fourier reconstruction. Third, a signal intensity correction is applied to remove artificial signal modulations due to eddy current-induced erroneous T2∗-weighting (i.e., Type 3 artifact). These systematic improvements will greatly increase the consistency and accuracy of DTI measurements, expanding the utility of DTI in translational applications where quantitative robustness is much needed. PMID:26413505

  14. Mathematical Investigation of Gamma Ray and Neutron Absorption Grid Patterns for Homeland Defense Related Fourier Imaging Systems

    NASA Technical Reports Server (NTRS)

    Boccio, Dona

    2003-01-01

    Terrorist suitcase nuclear devices typically using converted Soviet tactical nuclear warheads contain several kilograms of plutonium. This quantity of plutonium emits a significant number of gamma rays and neutrons as it undergoes radioactive decay. These gamma rays and neutrons normally penetrate ordinary matter to a significant distance. Unfortunately this penetrating quality of the radiation makes imaging with classical optics impractical. However, this radiation signature emitted by the nuclear source may be sufficient to be imaged from low-flying aerial platforms carrying Fourier imaging systems. The Fourier imaging system uses a pair of co-aligned absorption grids to measure a selected range of spatial frequencies from an object. These grids typically measure the spatial frequency in only one direction at a time. A grid pair that looks in all directions simultaneously would be an improvement over existing technology. A number of grid pairs governed by various parameters were investigated to solve this problem. By examining numerous configurations, it became apparent that an appropriate spiral pattern could be made to work. A set of equations was found to describe a grid pattern that produces straight fringes. Straight fringes represent a Fourier transform of a point source at infinity. An inverse Fourier transform of this fringe pattern would provide an accurate image (location and intensity) of a point source.

  15. Research on fast Fourier transforms algorithm of huge remote sensing image technology with GPU and partitioning technology.

    PubMed

    Yang, Xue; Li, Xue-You; Li, Jia-Guo; Ma, Jun; Zhang, Li; Yang, Jan; Du, Quan-Ye

    2014-02-01

    Fast Fourier transforms (FFT) is a basic approach to remote sensing image processing. With the improvement of capacity of remote sensing image capture with the features of hyperspectrum, high spatial resolution and high temporal resolution, how to use FFT technology to efficiently process huge remote sensing image becomes the critical step and research hot spot of current image processing technology. FFT algorithm, one of the basic algorithms of image processing, can be used for stripe noise removal, image compression, image registration, etc. in processing remote sensing image. CUFFT function library is the FFT algorithm library based on CPU and FFTW. FFTW is a FFT algorithm developed based on CPU in PC platform, and is currently the fastest CPU based FFT algorithm function library. However there is a common problem that once the available memory or memory is less than the capacity of image, there will be out of memory or memory overflow when using the above two methods to realize image FFT arithmetic. To address this problem, a CPU and partitioning technology based Huge Remote Fast Fourier Transform (HRFFT) algorithm is proposed in this paper. By improving the FFT algorithm in CUFFT function library, the problem of out of memory and memory overflow is solved. Moreover, this method is proved rational by experiment combined with the CCD image of HJ-1A satellite. When applied to practical image processing, it improves effect of the image processing, speeds up the processing, which saves the time of computation and achieves sound result. PMID:24822428

  16. Comparative analysis on viewing angle change in Fresnel and Fourier holographic images reconstructed by a tilted plane wave.

    PubMed

    Chae, Byung Gyu

    2014-05-20

    We carry out a comparative analysis on a viewing angle change in Fresnel and Fourier holographic images reconstructed by a tilted plane wave. A tilted plane wave illuminating an on-axis hologram generates a diffractive wave carrying the holographic image in a paraxial region of a new diffraction axis. The reconstructed image in the Fresnel hologram is deformed along the new viewing direction, which is well described as Affine transformation. In the Fourier holographic image, the replica of the image is formed without its deformation when the hologram is placed in the front focal plane of the lens, whereas in the case of a hologram that is located at a distance different from a focal length, image deformation arises. This property is investigated through numerical simulation based on a wide-angle diffraction phenomenon. We also perform a similar interpretation for high-order diffraction images appearing in the sampled Fourier hologram and discuss a method for enlarging the viewing angle of the holographic image. PMID:24922205

  17. Null test fourier domain alignment technique for phase-shifting point diffraction interferometer

    DOEpatents

    Naulleau, Patrick; Goldberg, Kenneth Alan

    2000-01-01

    Alignment technique for calibrating a phase-shifting point diffraction interferometer involves three independent steps where the first two steps independently align the image points and pinholes in rotation and separation to a fixed reference coordinate system, e.g, CCD. Once the two sub-elements have been properly aligned to the reference in two parameters (separation and orientation), the third step is to align the two sub-element coordinate systems to each other in the two remaining parameters (x,y) using standard methods of locating the pinholes relative to some easy to find reference point.

  18. An exact Fourier rebinning algorithm for 3D PET imaging using panel detectors

    NASA Astrophysics Data System (ADS)

    Kao, Chien-Min; Pan, Xiaochuan; Chen, Chin-Tu

    2004-06-01

    We present an exact Fourier-based algorithm for rebinning 3D data generated by a stationary dual-panel PET system to obtain direct slices for subsequent slice-by-slice reconstruction. The algorithm is computationally efficient and can greatly reduce the problem dimensionality and computation complexity of the reconstruction task. By conducting computer simulation studies in which the effects of scatter, randoms, detector response functions and attenuation correction are not considered, we demonstrate that direct slices generated by the proposed algorithm are quantitatively accurate and exhibit substantially better noise characteristics than the original direct slices. However, image artefacts, occurring at axial intensity discontinuities and in regions close to the axial axis, can be observed. With preliminary supporting evidence, we stipulate that these artefacts are due to errors in discrete implementations of partial derivatives of the 3D data. Although general weightings can be used in the proposed rebinning algorithm, in this work we only study the use of uniform weightings and the resulting direct slices exhibit non-uniform noise distributions, with the central slices being less noisy. In future studies, by using general weightings to reduce contributions of the data that are acquired at large oblique angles, we expect that more uniform noise distributions can be achieved, and axial blurring due to parallax errors can be reduced, at the cost of overall image variance.

  19. The study of a single BGC823 cell using Fourier transform infrared microspectroscopic imaging

    NASA Astrophysics Data System (ADS)

    Wang, Xin; Qi, Zeming; Wang, Shengyi; Liu, Gang; Gao, Helong; Tian, Yangchao

    2011-09-01

    In order to investigate gastric cancer at cellular and sub-cellular level, a single human gastric adenocarcinoma BGC823 cell was studied by an infrared microscope equipped with a focal plane array (FPA) detector. The spectra showed difference between the nucleus and the endoplasmic reticulum (ER) of the BGC823 cell. The peak of v asPO 2- was shifted to a higher wavenumber at the nucleus compared with that at the ER. The height ratios of 2954 cm -1/2922 cm -1 (CH 3/CH 2) and 1088 cm -1/1539 cm -1 (DNA/amide II) of the nucleus were significantly higher than those of the ER. Furthermore, chemical images reveal the intensity distributions of lipids, proteins and DNA of the single BGC823 cell, and the intense absorptions of proteins and DNA were observed in the nuclear region of the cell while the intense absorption of lipids was found in the ER region of the cell. The Fourier transform infrared (FTIR) microspectroscopic imaging result indicates the study of the single gastric cancer cell at sub-cellular level can be beneficial for knowing gastric cancer more which will be of great importance for the study and diagnosis of gastric cancer. The result also suggests that FPA is a useful tool in the study of a single cell and may be a powerful tool for study and diagnosis of gastric cancer.

  20. Compact snapshot birefringent imaging Fourier transform spectrometer for remote sensing and endoscopy

    NASA Astrophysics Data System (ADS)

    Kudenov, Michael W.; Banerjee, Bhaskar; Chan, Victoria C.; Dereniak, Eustace L.

    2012-09-01

    The design and implementation of a compact multiple-image Fourier transform spectrometer (FTS) is presented. Based on the multiple-image FTS originally developed by A. Hirai, the presented device offers significant advantages over his original implementation. Namely, its birefringent nature results in a common-path interferometer which makes the spectrometer insensitive to vibration. Furthermore, it enables the potential of making the instrument ultra-compact, thereby improving the portability of the sensor. The theory of the birefringent FTS is provided, followed by details of its specific embodiment. A laboratory proof of concept of the sensor, designed and developed at the Optical Detection Lab, is also presented. Spectral measurements of laboratory sources are provided, including measurements of light-emitting diodes and gas-discharge lamps. These spectra are verified against a calibrated Ocean Optics USB2000 spectrometer. Other data were collected outdoors and of a rat esophagus, demonstrating the sensor's ability to resolve spectral signatures in both standard outdoor lighting and environmental conditions, as well as in fluorescence spectroscopy.

  1. Imaging of the Internal Nasal Valve Using Long-Range Fourier Domain Optical Coherence Tomography

    PubMed Central

    Englhard, Anna S.; Wiedmann, Maximilian; Ledderose, Georg J.; Lemieux, Bryan; Badran, Alan; Chen, Zhongping; Betz, Christian S.; Wong, Brian J.

    2016-01-01

    Objectives/Hypothesis To evaluate for the first time the feasibility and methodology of long-range Fourier domain optical coherence tomography (LR-OCT) imaging of the internal nasal valve (INV) area in healthy individuals. Study Design Prospective individual cohort study. Methods For 16 individuals, OCT was performed in each nare. The angle and the cross-sectional area of the INV were measured. OCT images were compared to corresponding digital pictures recorded with a flexible endoscope. Results INV angle measured by OCT was found to be 18.3° ± 3.1° (mean ± standard deviation). The cross-sectional area was 0.65 ± 0.23 cm2. The INV angle measured by endoscopy was 18.8° ± 6.9°. There was no statistically significant difference between endoscopy and OCT concerning the mean INV angle (P = .778), but there was a significant difference in test precision (coefficient of variance 50% vs. 15%; P < .001). Conclusions LR-OCT proved to be a fast and easily performed method. OCT could accurately quantify the INV area. The values of the angle and the cross-sectional area of the INV were reproducible and correlated well with the data seen with other methods. Changes in size could be reliably delineated. Endoscopy showed similar values but was significantly less precise. PMID:26599137

  2. Design considerations for the development of a space qualification Short Wavelength Imaging Fourier Transform Spectrometer (SWIFTS)

    SciTech Connect

    Abbink, R.E.

    1997-06-01

    This document is the final report on work performed at Sandia National Laboratories during FY 1992 and 1993 for a Laboratory Directed Research and Development (LDRD) program to look at problems associated with the design and long term operation of a short wavelength imaging Fourier Transform (FT) spectrometer for use in space. In attempts to answer two fundamental questions: is a FT spectrometer with a resolution of 1 cm{sup {minus}1} covering the silicon detector wavelength range of 0.4 to 1.1 microns feasible in a long life space instrument and, if so, is it the best method of obtaining the desired information? Emphasis has been on identifying methods which minimize reliance on precision mechanical alignment and precise velocity control. An important consideration has also been to develop methods which will be compatible with a variety of self-scanning solid state imaging devices. A breadboard instrument was constructed using cube corner retroreflectors and a laser diode position reference. Some preliminary results are reported. This work is primarily intended to act as an aid to engineers at Sandia who wish to pursue the fabrication of a flight qualified instrument. The theoretical parts are intended to be somewhat tutorial in nature to aid the engineer who is not familiar with FT spectroscopy.

  3. Technical improvements and performances of SpIOMM: an imaging Fourier transform spectrometer for astronomy

    NASA Astrophysics Data System (ADS)

    Bernier, Anne-Pier; Charlebois, Maxime; Drissen, Laurent; Grandmont, Frédéric

    2008-07-01

    We present the most recent technical improvements on SpIOMM, an Imaging Fourier Transform Spectrometer (IFTS) attached to the 1.6 telescope of the Mont Megantic Observatory. The recent development of SpIOMM demonstrates that the concept of IFTS for ground telescopes is a promising astronomical 3D spectroscopy technique for multi-object spectroscopy and multi-band imaging. SpIOMM has been developed through a collaboration between Universite Laval and the industry (ABB Bomem). It is designed for optical observations from the near UV (350 nm) to the near IR (850 nm) with variable spectral resolution. The circular FOV of the instrument covers 12' in diameter. We have recently improved the servo system algorithm which now controls the mirror displacement and alignment at a rate of ~7kHz. Hardware improvements to the servo and the metrology system will be described along with their impacts on performance in the laboratory and in observing conditions. The instrument has successfully been operated at the 1.6 meter telescope this year using the revised control systems and acquired several datacubes. We will discuss some issues regarding the sensitivity to environmental conditions implied by the use of such an instrument. An overview of the datacube reduction procedure will show some solutions proposed for observational problems encountered that affect the quality of the data such as sky transmission variations, wind, changing gravity vector and temperature.

  4. Evaluation of the uncertainty of phase-difference measurements in (quasi-)Fourier transform digital holographic interferometry

    NASA Astrophysics Data System (ADS)

    Doval, Ángel F.; Trillo, Cristina; López Vázquez, José Carlos; Fernández, José L.

    2015-08-01

    Estimation of the uncertainty is an essential requisite for high-end measurement systems. In this communication we derive an expression to evaluate the standard uncertainty of the phase-difference measurements resulting from Fourier and quasi-Fourier transform digital holographic interferometry. We apply the law of propagation of uncertainty, as defined in the "Guide to the expression of uncertainty in measurement" (GUM), to the digital reconstruction of two holograms by Fourier transformation and to the subsequent calculation of the phase change between the holographic reconstructions. The resulting expression allows the evaluation of the uncertainty of the phase difference at every pixel in the reconstruction plane in terms of the measured hologram brightness values and their uncertainty at the whole of the pixels of the original digital holograms. This expression is simplified by assuming a linear dependence between the uncertainty and the local value of the original holograms; in that case, the local uncertainty of the phase difference can be evaluated from the local complex values of the reconstructed holograms. We assess the behavior of the method by comparing the predicted standard uncertainty with the sample variance obtained from experiments conducted under repeatability conditions, and found a good correlation between both quantities. This experimental procedure can be also used to calibrate the parameters of the linear function relating the uncertainty with the local value of the digital holograms, for a given set of operational conditions of the acquisition device.

  5. Image encryption based on the reality-preserving multiple-parameter fractional Fourier transform and chaos permutation

    NASA Astrophysics Data System (ADS)

    Lang, Jun

    2012-07-01

    In recent years, a number of methods have been proposed in the literature for the encryption of two-dimensional information by use of the fractional Fourier transform, but most of their encryptions are complex value and need digital hologram technique to record their encrypted information, which is inconvenience for digital transmission. In this paper, we first propose a novel reality-preserving multiple-parameter fractional Fourier transform which share real-valuedness outputs as well as most of the properties required for a fractional transform. Then we propose a new approach for image encryption based on the real-valuedness of the reality-preserving multiple-parameter fractional Fourier transform and the decorrelation property of chaotic maps in order to meet the requirements of the secure image transmission. In the proposed scheme, the image is encrypted by juxtaposition of sections of the image in the reality-preserving multiple-parameter fractional Fourier domains and the alignment of sections is determined by chaotic logistic maps. Numerical simulations are performed to demonstrate that the proposed method is reliable and more robust to blind decryption than several existing methods.

  6. Determination of grain size distribution function using two-dimensional Fourier transforms of tone pulse encoded images

    NASA Technical Reports Server (NTRS)

    Generazio, E. R.

    1986-01-01

    Microstructural images may be tone pulse encoded and subsequently Fourier transformed to determine the two-dimensional density of frequency components. A theory is developed relating the density of frequency components to the density of length components. The density of length components corresponds directly to the actual grain size distribution function from which the mean grain shape, size, and orientation can be obtained.

  7. Digital pathology with Fourier ptychography.

    PubMed

    Horstmeyer, Roarke; Ou, Xiaoze; Zheng, Guoan; Willems, Phil; Yang, Changhuei

    2015-06-01

    Fourier ptychographic microscopy (FPM) is a recently introduced method of acquiring high-resolution, wide field of view (FOV) giga-pixel histology images. The FPM procedure first acquires a sequence of low-resolution images of a sample under variable-angle illumination. It then combines these images using a novel phase retrieval algorithm to improve the employed microscope's resolution beyond its conventional limit. Here, we first describe how FPM's resolution improvement can enhance wide FOV histology imaging. Second, we show that FPM also records a thin sample's optical phase, which can help pathologists digitally extract as much information as possible from a given histology slide. PMID:25481664

  8. Fourier transform infrared spectroscopic imaging identifies early biochemical markers of tissue damage

    NASA Astrophysics Data System (ADS)

    Varma, Vishal K.; Ohlander, Samuel; Nguyen, Peter; Vendryes, Christopher; Parthiban, Sujeeth; Hamilton, Blake; Wallis, M. Chad; Kajdacsy-Balla, Andre; Hannaford, Blake; Lendvay, Thomas; Hotaling, James M.; Walsh, Michael J.

    2014-03-01

    Fourier Transform Infrared (FT-IR) spectroscopic imaging can allow for the rapid imaging of tissue biochemistry in a label-free and non-perturbing fashion. With the rapid adoption of new minimally invasive surgery (MIS) technologies over the last 20 years, adequate skill to safely and effectively use these technologies may not be achieved and risk of undue physical pressure being placed on tissues is a concern. Previous work has demonstrated that a number of histological stains can detect tissue damage, however, this process requires the initiation and progression of a signaling cascade that results in the epitope of interest being expressed. We proposed to identify the early biochemical markers associated with physical tissue damage from applied forces, thus not requiring transcriptional and translational protein synthesis as traditional immunohistochemistry does. To demonstrate that FT-IR can measure biochemical changes in tissues that have undergone physical force, we took ex-vivo lamb's liver that had been freshly excised and applied varying levels of physical pressure (0kPa to 30kPa). Tissues were then formalin-fixed, paraffin-embedded, and sectioned on to glass for H and E staining to identify damage and on to an IR slide for FT-IR imaging. Regions of interest containing hepatocytes were identified and average FT-IR spectra were extracted from the damaged and undamaged livers. FT-IR spectra showed clear biochemical changes associated with tissue damage. In addition, chemical changes could be observed proceeding histological changes observed when using conventional staining approaches.

  9. Spectral calibration of the space-borne infrared imaging Fourier transform spectrometer

    NASA Astrophysics Data System (ADS)

    Liu, Peng; Wang, Zhanhu; Wang, Peigang; Hua, Jianwen

    2009-07-01

    The Space-borne Infrared Imaging Fourier Transform Spectrometer (SBFTS) carried by FY-4 meteorological satellite is one of infrared remote sensing instruments. It acquires the temperature, pressure and humidity of atmosphere on geostationary orbit, and supplies the input data for numerical weather prediction. It not only can detect the spectrum of the target but also can imaging. The SBFTS carry 16×4 plane array detectors. For the proper use of the SBFTS it is imperative to provide high quality spectral characterization and characterizations of the instrument line shape (ILS). Objective: This paper's mainly analyses the off-axis factor that influence the ILS of SBFTS and convinces it through experiment. And the spectral calibration of SBFTS is according to the ILS. Methods: The accuracy of spectral-calibration of SBFTS lies on its ILS. First, the main factors that will influence the ILS are discussed here. They are the finite optical path difference and the off-axes effect because of using plane array detectors. The ILS of Fourier transform spectroscopy is influenced by the angular distribution of light in the interferometer's off-axis detector. The paper studies the effect to spectral calibration by off-axis detectors, and then makes ILS simulation for rectangular detector based on the sounder's 16×4 plane array detectors structure. The absorption line shape of CO is Lorentzian distribution in the laboratory environment. Now the ILS and the absorption line shape of the CO are given. They can be combined to the instrument detecting line shape theoretically. So the theoretical position of the absorption peak detected by the SBFTS is acquired. The frequency of absorption peak is red-shift. And the spectrum is broadened. According to the reference spectrum the spectrum calibration coefficients of each pixel is derived. And the absorption peak of CO also can be detected using the gas cell methodology. Finally the calibration coefficients are used to calibrate the spectrum of CO detected by the SBFTS. Results: The spectral-calibration coefficients of each pixel are presented and proved by the calibration experiment of CO. The relative calibration accuracy is up to 10-6.

  10. Nonlinear phase interaction between nonstationary signals: a comparison study of methods based on Hilbert-Huang and Fourier transforms.

    PubMed

    Lo, Men-Tzung; Novak, Vera; Peng, C-K; Liu, Yanhui; Hu, Kun

    2009-06-01

    Phase interactions among signals of physical and physiological systems can provide useful information about the underlying control mechanisms of the systems. Physical and biological recordings are often noisy and exhibit nonstationarities that can affect the estimation of phase interactions. We systematically studied effects of nonstationarities on two phase analyses including (i) the widely used transfer function analysis (TFA) that is based on Fourier decomposition and (ii) the recently proposed multimodal pressure flow (MMPF) analysis that is based on Hilbert-Huang transform (HHT)-an advanced nonlinear decomposition algorithm. We considered three types of nonstationarities that are often presented in physical and physiological signals: (i) missing segments of data, (ii) linear and step-function trends embedded in data, and (iii) multiple chaotic oscillatory components at different frequencies in data. By generating two coupled oscillatory signals with an assigned phase shift, we quantify the change in the estimated phase shift after imposing artificial nonstationarities into the oscillatory signals. We found that all three types of nonstationarities affect the performances of the Fourier-based and the HHT-based phase analyses, introducing bias and random errors in the estimation of the phase shift between two oscillatory signals. We also provided examples of nonstationarities in real physiological data (cerebral blood flow and blood pressure) and showed how nonstationarities can complicate result interpretation. Furthermore, we propose certain strategies that can be implemented in the TFA and the MMPF methods to reduce the effects of nonstationarities, thus improving the performances of the two methods. PMID:19658541

  11. Design of a high aperture compression ratio, dual-band static Fourier transform imaging spectrometer for remote sensing

    NASA Astrophysics Data System (ADS)

    Zou, Chun-bo; Hu, Bing-Liang; Li, Li-bo; Bai, Qing-Lan; Sun, Xin; Li, Ran; Yang, Jian-Feng

    2014-11-01

    A novel dual-band static Fourier transform imaging spectrometer was designed, which was the spatio-temporally modulated imaging Fourier transform spectrometer based on Sagnac interferometer. The approach represented a simplification and mass reduction over the traditional approach. It could obtain two-dimensional spatial images and one dimensional spectral image in two bands simultaneously. The two bands was separated through a dichroic prism and imaging in two detectors. one band was the visible and near infrared band, with the spectral range 400nm-1000nm and spectral resolution 187.5 wave numbers; the other was the short wave infrared band, with the spectral range 1000nm- 2500nm and spectral resolution 150 wave numbers. To reduce the size of the Interferometer, a high aperture compression ratio telescope system was designed before. The optical aperture was compressed to 1/10, and the volume of interferometer was reduced to 1/1000. For the convenience of engineering implementation, the telescope was composed of two no-aberration object lens: fore-lens and Collimating lens. The two band imaging spectrometers shared the primary lens and the second lens of the fore-lens and use their own collimating lens, interferometers and Fourier transform lens. The collimating lens and the Fourier transform lens of each spectrometer could be designed to the same structural style and parameters. The both spectrometers had a focal length of 1000mm, F number of 5, FOV(field of view) of 1°. Moreover, both image qualities were close to the diffraction limit, the distortion was less than 2%. The advantage of the instrument was that dual band spectral image could be acquired at the same time and the interferometer was miniaturized extremely in the case of unchanged technical indicators.

  12. Theoretical simulation of noncontact AFM images of Si(111) ?3?3-Ag surface based on Fourier expansion method

    NASA Astrophysics Data System (ADS)

    Sasaki, Naruo; Aizawa, Hideaki; Tsukada, Masaru

    2000-04-01

    A Fourier expansion method is introduced to simulate the noncontact atomic force microscopy (NC-AFM) images in an efficient way, where three dimensional (3D) tip-surface interaction force distribution calculated by the first-principles density functional (LDA) calculations are fitted to an analytical function. As an example of application of this method, we adopt a Si(111) ?3?3 R30-Ag surface. Force spectroscopies and 2D images for different tip height are presented.

  13. Fourier plane colorimetric sensing using broadband imaging of surface plasmons and application to biosensing

    NASA Astrophysics Data System (ADS)

    Arora, P.; Krishnan, A.

    2015-12-01

    We demonstrate an optical technique for refractive index and thickness sensing of sub-wavelength-thick dielectric analytes. The technique utilizes the broadband, multimode, directional leakage radiation arising from the excitation of hybrid mode surface plasmons (SP) on low aspect ratio periodic plasmonic substrates with period ≈λ. The approach requires relaxed fabrication tolerances compared to extra ordinary transmission-based sensing techniques, wherein minor shifts in the fabricated dimensions result in a very large change from the designed resonant wavelength. We show that refractive index perturbations due to about 10-nm-thick dielectric can be captured optically by the usage of carefully designed plasmonic substrates, a halogen lamp source, free-space optical components, polarizers, and a low-end, consumer-grade charge coupled device camera. The plasmonic substrates were designed for converting the signature of hybrid mode SP excitation into a transmission peak by utilizing a thin homogeneous metal layer sandwiched between the periodic plasmonic structures and the substrate. The resonance is highly sensitive to the refractive index and thickness of the analyte superstrate. The excitation of hybrid mode SP results in a polarization rotation of 90° of the leaked radiation at resonant wavelength. In order to eliminate the problem of image registration (i.e., placing the same feature in the same pixel of the image, for comparison before and after a change in refractive index) for sensing, we perform the color analysis in the Fourier plane. The change in color of the bright emitted spot with highest momentum, corresponding to the leakage of fundamental SP mode, was used to measure the changes in refractive index, whereas the number and color of spots of lower momenta, corresponding to higher-order Fabry Perot modes, was used to measure the variation in thickness. We further show that the Fourier plane analysis can also be used to sense the index of thicker dielectrics, where real plane image analysis may fail to sense index perturbations, simply due to superposition of different modes in the real plane images of such substrates. Control experiments and analysis revealed a refractive index resolution of 10-5 RIU. The results were correlated with simulations to establish the physical origin of the change in the fundamental mode and higher-order modes due to the refractive index and thickness of analyte. As a demonstration of an application and to test the limits of sensing, the substrates were used to image the surface functionalization using 2-nm-thick 11-mercaptoundecanoic acid and immobilization of 7-nm-thick mouse anti-human IgG antibody. In biological systems, where a priori knowledge about a process step is available, where accurate chemical composition testing is not necessary or possible, the presented method could be used to study the surface changes using a label-free sensing mechanism.

  14. Vibrational mapping of sinonasal lesions by Fourier transform infrared imaging spectroscopy.

    PubMed

    Giorgini, Elisabetta; Sabbatini, Simona; Conti, Carla; Rubini, Corrado; Rocchetti, Romina; Re, Massimo; Vaccari, Lisa; Mitri, Elisa; Librando, Vito

    2015-12-01

    Fourier transform infrared imaging (FTIRI) is a powerful tool for analyzing biochemical changes in tumoral tissues. The head and neck region is characterized by a great variety of lesions, with different degrees of malignancy, which are often difficult to diagnose. Schneiderian papillomas are sinonasal benign neoplasms arising from the Schneiderian mucosa; they can evolve into malignant tumoral lesions (squamous cell carcinoma). In addition, they can sometimes be confused with the more common inflammatory polyps. Therefore, an early and definitive diagnosis of this pathology is mandatory. Progressing in our research on the study of oral cavity lesions, 15 sections consisting of inflammatory sinonasal polyps, benign Schneiderian papillomas, and sinonasal undifferentiated carcinomas were analyzed using FTIRI. To allow a rigorous description of these pathologies and to gain objective diagnosis, the epithelial layer and the adjacent connective tissue of each section were separately investigated by following a multivariate analysis approach. According to the nature of the lesion, interesting modifications were detected in the average spectra of the different tissue components, above all in the lipid and protein patterns. Specific band-area ratios acting as spectral markers of the different pathologies were also highlighted. PMID:26677069

  15. Fourier transform infrared spectroscopic imaging of cardiac tissue to detect collagen deposition after myocardial infarction

    NASA Astrophysics Data System (ADS)

    Cheheltani, Rabee; Rosano, Jenna M.; Wang, Bin; Sabri, Abdel Karim; Pleshko, Nancy; Kiani, Mohammad F.

    2012-05-01

    Myocardial infarction often leads to an increase in deposition of fibrillar collagen. Detection and characterization of this cardiac fibrosis is of great interest to investigators and clinicians. Motivated by the significant limitations of conventional staining techniques to visualize collagen deposition in cardiac tissue sections, we have developed a Fourier transform infrared imaging spectroscopy (FT-IRIS) methodology for collagen assessment. The infrared absorbance band centered at 1338 cm-1, which arises from collagen amino acid side chain vibrations, was used to map collagen deposition across heart tissue sections of a rat model of myocardial infarction, and was compared to conventional staining techniques. Comparison of the size of the collagen scar in heart tissue sections as measured with this methodology and that of trichrome staining showed a strong correlation (R=0.93). A Pearson correlation model between local intensity values in FT-IRIS and immuno-histochemical staining of collagen type I also showed a strong correlation (R=0.86). We demonstrate that FT-IRIS methodology can be utilized to visualize cardiac collagen deposition. In addition, given that vibrational spectroscopic data on proteins reflect molecular features, it also has the potential to provide additional information about the molecular structure of cardiac extracellular matrix proteins and their alterations.

  16. Fourier-Doppler Imaging of Line Profile Variations in ζ Ophiuchi

    NASA Astrophysics Data System (ADS)

    Jankov, S.; Janot-Pacheco, E.; Leister, N. V.

    2000-09-01

    We present, for the first time, the Fourier-Doppler Imaging (FDI) analysis of periodic line profile variations in a ζ Oph-type star. For this purpose we obtained, in the period from 1996 May 3 to May 5, a total of 242 high-resolution, high signal-to-noise ratio spectra of the Be star ζ Oph itself. Using the FDI technique, we examine the variations in both time and wavelength and complement it with time series analysis. This kind of analysis is valid for both the nonradial pulsator model and the rotation modulation model, but we discuss the results in terms of the former model, considering it the more likely explanation for the observed line profile variability. Two distinct groups of modes are detected: medium (4<=l~|m|<=8) and high-degree modes (which could be associated with 13<=l~|m|<=17). It is shown that the high-frequency oscillations were strongly confined to an equatorial belt narrower than 20° and that the line profile variability was caused predominantly by sectoral modes, although tesseral modes |m|=l-1 are not excluded in taking into account the effect of fast rotation. We discuss the modal nature of the waves with respect to the characteristic oscillation periods in the corotating frame and the high amplitude of the projected rotational velocity variations (~20 km s-1).

  17. Vibrational mapping of sinonasal lesions by Fourier transform infrared imaging spectroscopy

    NASA Astrophysics Data System (ADS)

    Giorgini, Elisabetta; Sabbatini, Simona; Conti, Carla; Rubini, Corrado; Rocchetti, Romina; Re, Massimo; Vaccari, Lisa; Mitri, Elisa; Librando, Vito

    2015-12-01

    Fourier transform infrared imaging (FTIRI) is a powerful tool for analyzing biochemical changes in tumoral tissues. The head and neck region is characterized by a great variety of lesions, with different degrees of malignancy, which are often difficult to diagnose. Schneiderian papillomas are sinonasal benign neoplasms arising from the Schneiderian mucosa; they can evolve into malignant tumoral lesions (squamous cell carcinoma). In addition, they can sometimes be confused with the more common inflammatory polyps. Therefore, an early and definitive diagnosis of this pathology is mandatory. Progressing in our research on the study of oral cavity lesions, 15 sections consisting of inflammatory sinonasal polyps, benign Schneiderian papillomas, and sinonasal undifferentiated carcinomas were analyzed using FTIRI. To allow a rigorous description of these pathologies and to gain objective diagnosis, the epithelial layer and the adjacent connective tissue of each section were separately investigated by following a multivariate analysis approach. According to the nature of the lesion, interesting modifications were detected in the average spectra of the different tissue components, above all in the lipid and protein patterns. Specific band-area ratios acting as spectral markers of the different pathologies were also highlighted.

  18. First results and current development of SpIOMM: an imaging Fourier transform spectrometer for astronomy

    NASA Astrophysics Data System (ADS)

    Bernier, A.-P.; Grandmont, F.; Rochon, J.-F.; Charlebois, M.; Drissen, L.

    2006-06-01

    We present an overview of SpIOMM, an Imaging Fourier Transform Spectrometer (IFTS) for astronomy developed at University Laval in collaboration with ABB, INO and the Canadian Space Agency. SpIOMM, attached to the 1.6 meter (f/8) telescope at the Observatoire du mont Megantic in Quebec. It is a Michelson-type interferometer capable of obtaining the visible spectrum (from 350 nm to 900 nm) of every light source within its 12 arcminute circular field of view. This design will allow the correction of variable sky transmission. It consists of a dual output port and the total throughput is exploited by two CCDs used as detectors. We present the concept and design of this unique instrument. A metrology system combined with a dynamic alignment assures a good sampling and mirror alignment during the entire acquisition sequence. This particular servo control is explained and demonstrated and its capabilities and performance are discussed. We introduce the use of specific bandpass filters centered on the most important groups of emission lines which, when combined with spectral folding algorithms, allows us to reach high spectral resolution (R = 25 000, or 1 cm -1). Astronomical data collected by SpIOMM in 2004-2005 are also presented.

  19. ORBS: A data reduction software for the imaging Fourier transform spectrometers SpIOMM and SITELLE

    NASA Astrophysics Data System (ADS)

    Martin, T.; Drissen, L.; Joncas, G.

    2012-09-01

    SpIOMM (Spectromètre-Imageur de l'Observatoire du Mont Mégantic) is still the only operational astronomical Imaging Fourier Transform Spectrometer (IFTS) capable of obtaining the visible spectrum of every source of light in a field of view of 12 arc-minutes. Even if it has been designed to work with both outputs of the Michelson interferometer, up to now only one output has been used. Here we present ORBS (Outils de Réduction Binoculaire pour SpIOMM/SITELLE), the reduction software we designed in order to take advantage of the two output data. ORBS will also be used to reduce the data of SITELLE (Spectromètre-Imageur pour l' Étude en Long et en Large des raies d' Émissions) { the direct successor of SpIOMM, which will be in operation at the Canada-France- Hawaii Telescope (CFHT) in early 2013. SITELLE will deliver larger data cubes than SpIOMM (up to 2 cubes of 34 Go each). We thus have made a strong effort in optimizing its performance efficiency in terms of speed and memory usage in order to ensure the best compliance with the quality characteristics discussed with the CFHT team. As a result ORBS is now capable of reducing 68 Go of data in less than 20 hours using only 5 Go of random-access memory (RAM).

  20. Fuzzy Logic Classification of Imaging Laser Desorption Fourier Transform Mass Spectrometry Data

    SciTech Connect

    Timothy R. McJunkin; Jill R. Scott

    2008-06-01

    The fuzzy logic method is applied to classification of mass spectra obtained with an imaging internal source Fourier transform mass spectrometer (I2LD-FTMS). Traditionally, an operator uses the relative abundance of ions with specific mass-to-charge (m/z) ratios to categorize spectra. An operator does this by comparing the spectrum of m/z versus abundance of an unknown sample against a library of spectra from known samples. Automated positioning and acquisition allow the I2LD-FTMS to acquire data from very large grids, which would require classification of up to 3600 spectra per hour to keep pace with the acquisition. The tedious job of classifying numerous spectra generated in an I2LD-FTMS imaging application can be replaced by a fuzzy rule base if the cues an operator uses can be encapsulated. Appropriate methods for assigning fuzzy membership values for inputs (e.g., mass spectrum abundances) and choice of fuzzy inference operators to translate linguistic antecedent into confidence values for the consequence (or in this case the classification) is followed by using the maximum confidence and a necessary minimum threshold for making a crisp decision. This paper also describes a method for gathering statistics on ions, which are not currently used in the rule base, but which may be candidates for making the rule base more accurate and complete or to form new rule bases based on data obtained from known samples. A spatial method for classifying spectra with low membership values, based on neighboring sample classifications, is also presented.

  1. Radiometric modeling and calibration of the Geostationary Imaging Fourier Transform Spectrometer (GIFTS) ground based measurement experiment

    NASA Astrophysics Data System (ADS)

    Tian, Jialin; Smith, William L.; Gazarik, Michael J.

    2008-12-01

    The ultimate remote sensing benefits of the high resolution Infrared radiance spectrometers will be realized with their geostationary satellite implementation in the form of imaging spectrometers. This will enable dynamic features of the atmosphere's thermodynamic fields and pollutant and greenhouse gas constituents to be observed for revolutionary improvements in weather forecasts and more accurate air quality and climate predictions. As an important step toward realizing this application objective, the Geostationary Imaging Fourier Transform Spectrometer (GIFTS) Engineering Demonstration Unit (EDU) was successfully developed under the NASA New Millennium Program, 2000-2006. The GIFTS-EDU instrument employs three focal plane arrays (FPAs), which gather measurements across the long-wave IR (LWIR), short/mid-wave IR (SMWIR), and visible spectral bands. The GIFTS calibration is achieved using internal blackbody calibration references at ambient (260 K) and hot (286 K) temperatures. In this paper, we introduce a refined calibration technique that utilizes Principle Component (PC) analysis to compensate for instrument distortions and artifacts, therefore, enhancing the absolute calibration accuracy. This method is applied to data collected during the GIFTS Ground Based Measurement (GBM) experiment, together with simultaneous observations by the accurately calibrated AERI (Atmospheric Emitted Radiance Interferometer), both simultaneously zenith viewing the sky through the same external scene mirror at ten-minute intervals throughout a cloudless day at Logan Utah on September 13, 2006. The accurately calibrated GIFTS radiances are produced using the first four PC scores in the GIFTS-AERI regression model. Temperature and moisture profiles retrieved from the PC-calibrated GIFTS radiances are verified against radiosonde measurements collected throughout the GIFTS sky measurement period. Using the GIFTS GBM calibration model, we compute the calibrated radiances from data collected during the moon tracking and viewing experiment events. From which, we derive the lunar surface temperature and emissivity associated with the moon viewing measurements.

  2. Security enhancement of a phase-truncation based image encryption algorithm.

    PubMed

    Wang, Xiaogang; Zhao, Daomu

    2011-12-20

    The asymmetric cryptosystem, which is based on phase-truncated Fourier transforms (PTFTs), can break the linearity of conventional systems. However, it has been proven to be vulnerable to a specific attack based on iterative Fourier transforms when the two random phase masks are used as public keys to encrypt different plaintexts. An improvement from the asymmetric cryptosystem may be taken by relocating the amplitude values in the output plane. In this paper, two different methods are adopted to realize the amplitude modulation of the output image. The first one is to extend the PTFT-based asymmetrical cryptosystem into the anamorphic fractional Fourier transform domain directly, and the second is to add an amplitude mask in the Fourier plane of the encryption scheme. Some numerical simulations are presented to prove the good performance of the proposed cryptosystems. PMID:22193194

  3. Sub-pixel spatial resolution wavefront phase imaging

    NASA Technical Reports Server (NTRS)

    Stahl, H. Philip (Inventor); Mooney, James T. (Inventor)

    2012-01-01

    A phase imaging method for an optical wavefront acquires a plurality of phase images of the optical wavefront using a phase imager. Each phase image is unique and is shifted with respect to another of the phase images by a known/controlled amount that is less than the size of the phase imager's pixels. The phase images are then combined to generate a single high-spatial resolution phase image of the optical wavefront.

  4. Balloon Demonstrator Imaging Fourier Transform Spectrometer for the Measurement of Methane and Carbon Dioxide over the Arctic

    NASA Astrophysics Data System (ADS)

    Vaziri Z., Zahra; McElroy, Charles T.; Feng, Keh-Harng; Moeini, Omid; Walker, Kaley A.; Martin, Randall; Grandmont, Frederic J.

    2015-04-01

    Arctic climate is changing more rapidly than expected. Multi-year ice is melting and opening the way for shipping and exploration activity for natural resources which in turn increases air pollution. Observing greenhouse gases on a global scale is essential to monitor climate change, especially in the Arctic. Several space missions monitor trace gasses but are in low-earth, sun synchronous orbits and do not have a 24/7 view of northern latitudes. The Canadian Space Agency (CSA), along with other Canadian government departments, is proposing the Polar Communications and Weather (PCW) satellite to provide weather, communication and atmospheric composition information over the Arctic. The use of two satellites in out-of-phase highly elliptical three-apogee orbits with an apogee at ~40,000 km over the Arctic, will provide continuous quasi-geostationary viewing of the northern latitudes. The planned meteorological instrument for the PCW mission is a 21-channel spectral imager with UV, visible, NIR and MIR channels, similar to MODIS and ABI, capable of measuring several different trace gasses. This paper will focus on the development of an Imaging Fourier Transform Spectrometer (IFTS) to be flown on a high-altitude balloon to demonstrate the capacity to monitor methane and carbon dioxide in the Arctic as part of the PHEOS-WCA (Polar Highly Elliptical Orbit Science - Weather, Climate and Air quality) instrument suit; a science complement to the PCW mission. Funding through the CSA Flights for the Advancement of Science and Technology (FAST) program is in place to develop the demonstrator IFTS to show that measurements of methane and carbon dioxide can be collected from space in the 1.6 µm band. The characteristics of the instrument and plans for the balloon flight will be discussed and details of the PCW mission and PHEOS-WCA component will be presented. The authors acknowledge support of the PHEOS-WCA science team.

  5. Radiometric and spectral calibrations of the Geostationary Imaging Fourier Transform Spectrometer (GIFTS) using principle component analysis

    NASA Astrophysics Data System (ADS)

    Tian, Jialin; Smith, William L.; Gazarik, Michael J.

    2008-10-01

    The ultimate remote sensing benefits of the high resolution Infrared radiance spectrometers will be realized with their geostationary satellite implementation in the form of imaging spectrometers. This will enable dynamic features of the atmosphere's thermodynamic fields and pollutant and greenhouse gas constituents to be observed for revolutionary improvements in weather forecasts and more accurate air quality and climate predictions. As an important step toward realizing this application objective, the Geostationary Imaging Fourier Transform Spectrometer (GIFTS) Engineering Demonstration Unit (EDU) was successfully developed under the NASA New Millennium Program, 2000-2006. The GIFTS-EDU instrument employs three focal plane arrays (FPAs), which gather measurements across the long-wave IR (LWIR), short/mid-wave IR (SMWIR), and visible spectral bands. The raw GIFTS interferogram measurements are radiometrically and spectrally calibrated to produce radiance spectra, which are further processed to obtain atmospheric profiles via retrieval algorithms. The radiometric calibration is achieved using internal blackbody calibration references at ambient (260 K) and hot (286 K) temperatures. The absolute radiometric performance of the instrument is affected by several factors including the FPA off-axis effect, detector/readout electronics induced nonlinearity distortions, and fore-optics offsets. The GIFTS-EDU, being the very first imaging spectrometer to use ultra-high speed electronics to readout its large area format focal plane array detectors, operating at wavelengths as large as 15 microns, possessed non-linearity's not easily removable in the initial calibration process. In this paper, we introduce a refined calibration technique that utilizes Principle Component (PC) analysis to compensate for instrument distortions and artifacts remaining after the initial radiometric calibration process, thus, further enhance the absolute calibration accuracy. This method is applied to data collected during an atmospheric measurement experiment with the GIFTS, together with simultaneous observations by the accurately calibrated AERI (Atmospheric Emitted Radiance Interferometer), both simultaneously zenith viewing the sky through the same external scene mirror at ten-minute intervals throughout a cloudless day at Logan Utah on September 13, 2006. The PC vectors of the calibrated radiance spectra are defined from the AERI observations and regression matrices relating the initial GIFTS radiance PC scores to the AERI radiance PC scores are calculated using the least squares inverse method. A new set of accurately calibrated GIFTS radiances are produced using the first four PC scores in the regression model. Temperature and moisture profiles retrieved from the PC-calibrated GIFTS radiances are verified against radiosonde measurements collected throughout the GIFTS sky measurement period.

  6. Reconstruction of color biomedical images by means of quaternion generic Jacobi-Fourier moments in the framework of polar pixels.

    PubMed

    Camacho-Bello, César; Padilla-Vivanco, Alfonso; Toxqui-Quitl, Carina; Báez-Rojas, José Javier

    2016-01-01

    A detailed analysis of the quaternion generic Jacobi-Fourier moments (QGJFMs) for color image description is presented. In order to reach numerical stability, a recursive approach is used during the computation of the generic Jacobi radial polynomials. Moreover, a search criterion is performed to establish the best values for the parameters [Formula: see text] and [Formula: see text] of the radial Jacobi polynomial families. Additionally, a polar pixel approach is taken into account to increase the numerical accuracy in the calculation of the QGJFMs. To prove the mathematical theory, some color images from optical microscopy and human retina are used. Experiments and results about color image reconstruction are presented. PMID:27014716

  7. Imaging of the three-dimensional alveolar structure and the alveolar mechanics of a ventilated and perfused isolated rabbit lung with Fourier domain optical coherence tomography

    NASA Astrophysics Data System (ADS)

    Popp, Alexander; Wendel, Martina; Knels, Lilla; Koch, T.; Koch, Edmund

    2006-01-01

    In this feasibility study, Fourier domain optical coherence tomography (FDOCT) is used for visualizing the 3-D structure of fixated lung parenchyma and to capture real-time cross sectional images of the subpleural alveolar mechanics in a ventilated and perfused isolated rabbit lung. The compact and modular setup of the FDOCT system allows us to image the first 500 µm of subpleural lung parenchyma with a 3-D resolution of 16×16×8 µm (in air). During mechanical ventilation, real-time cross sectional FDOCT images visualize the inflation and deflation of alveoli and alveolar sacks (acini) in successive images of end-inspiratory and end-expiratory phase. The FDOCT imaging shows the relation of local alveolar mechanics to the setting of tidal volume (VT), peak airway pressure, and positive end-expiratory pressure (PEEP). Application of PEEP leads to persistent recruitment of alveoli and acini in the end-expiratory phase, compared to ventilation without PEEP where alveolar collapse and reinflation are observed. The imaging of alveolar mechanics by FDOCT will help to determine the amount of mechanical stress put on the alveolar walls during tidal ventilation, which is a key factor in understanding the development of ventilator induced lung injury (VILI).

  8. Lossless compression of the geostationary imaging Fourier transform spectrometer (GIFTS) data via predictive partitioned vector quantization

    NASA Astrophysics Data System (ADS)

    Huang, Bormin; Wei, Shih-Chieh; Huang, Allen H.-L.; Smuga-Otto, Maciek; Knuteson, Robert; Revercomb, Henry E.; Smith, William L., Sr.

    2007-09-01

    The Geostationary Imaging Fourier Transform Spectrometer (GIFTS), as part of NASA's New Millennium Program, is an advanced instrument to provide high-temporal-resolution measurements of atmospheric temperature and water vapor, which will greatly facilitate the detection of rapid atmospheric changes associated with destructive weather events, including tornadoes, severe thunderstorms, flash floods, and hurricanes. The Committee on Earth Science and Applications from Space under the National Academy of Sciences recommended that NASA and NOAA complete the fabrication, testing, and space qualification of the GIFTS instrument and that they support the international effort to launch GIFTS by 2008. Lossless data compression is critical for the overall success of the GIFTS experiment, or any other very high data rate experiment where the data is to be disseminated to the user community in real-time and archived for scientific studies and climate assessment. In general, lossless data compression is needed for high data rate hyperspectral sounding instruments such as GIFTS for (1) transmitting the data down to the ground within the bandwidth capabilities of the satellite transmitter and ground station receiving system, (2) compressing the data at the ground station for distribution to the user community (as is traditionally performed with GOES data via satellite rebroadcast), and (3) archival of the data without loss of any information content so that it can be used in scientific studies and climate assessment for many years after the date of the measurements. In this paper we study lossless compression of GIFTS data that has been collected as part of the calibration or ground based tests that were conducted in 2006. The predictive partitioned vector quantization (PPVQ) is investigated for higher lossless compression performance. PPVQ consists of linear prediction, channel partitioning and vector quantization. It yields an average compression ratio of 4.65 on the GIFTS test data, which significantly outperforms the standard compression methods such as JPEG-2000, JPEG-LS, and CCSDS IDC 9/7M & 5/3.

  9. Spatial-phase code-division multiple-access system with multiplexed Fourier holography switching for reconfigurable optical interconnection.

    PubMed

    Takasago, K; Takekawa, M; Shirakawa, A; Kannari, F

    2000-05-10

    A new, to our knowledge, space-variant optical interconnection system based on a spatial-phase code-division multiple-access technique with multiplexed Fourier holography is described. In this technique a signal beam is spread over wide spatial frequencies by an M-sequence pseudorandom phase code. At a receiver side a selected signal beam is properly decoded, and at the same time its spatial pattern is shaped with a Fourier hologram, which is recorded by light that is encoded with the same M-sequence phase mask as the desired signal beam and by light whose spatial beam pattern is shaped to a signal routing pattern. Using the multiplexed holography, we can simultaneously route multisignal flows into individually specified receiver elements. The routing pattern can also be varied by means of switching the encoding phase code or replacing the hologram. We demonstrated a proof-of-principle experiment with a doubly multiplexed hologram that enables simultaneous routing of two signal beams. Using a numerical model, we showed that the proposed scheme can manage more than 250 routing patterns for one signal flow with one multiplexed hologram at a signal-to-noise ratio of ~5. PMID:18345134

  10. Mercury cadmium telluride focal-plane array detection for mid-infrared Fourier-transform spectroscopic imaging.

    PubMed

    Kidder, L H; Levin, I W; Lewis, E N; Kleiman, V D; Heilweil, E J

    1997-05-15

    By combining step-scan Fourier-transform Michelson interferometry, an infrared microscope, and mercury cadmium telluride focal-plane array image detection we have constructed a mid-infrared spectroscopic imaging system that simultaneously records high-fidelity images and spectra of materials from 3500 to 900 cm(-1) (2.8 to 11 microm) at a variety of spectral resolutions. The fidelity of the spectral images is determined by the pixel number density of the focal-plane array. Step-scan imaging principles and instrument design details are outlined. Spatial resolution measurements and infrared chemical imaging examples are presented, and the results are discussed with respect to implications for chemical analysis of biosystems and composite materials. PMID:18185647

  11. Investigation of Moiré Pattern-based Phase Retrieval Approach for Differential Phase-contrast Cone Beam CT Imaging Using a Hospital-grade Tube

    PubMed Central

    Cai, Weixing; Ning, Ruola; Yu, Yang; Liu, Jiangkun; Conover, David

    2012-01-01

    The phase stepping algorithm is commonly used for phase retrieval in grating-based differential phase-contrast (DPC) imaging, which requires multiple intensity images to compute one DPC image. It is not efficient for data acquisition, especially in the case of dynamic imaging using either DPC imaging or DPC-based come beam CT (DPC-CBCT) imaging. A Fourier transform-based approach has been developed for fringe pattern analysis in optics, and it was recently implemented into a synchrotron-based DPC tomography system. In this research, this approach is further developed for a bench-top DPC-CBCT imaging system with a hospital-grade x-ray tube. The key idea is to separate carrier fringes and object information in Fourier domain of the interferogram and to reconstruct the differentiated phase information using the object information. Only one interferogram is required for phase retrieval at a cost of spatial resolution. The fringes of moiré patterns are used as the carrier fringes, and a phantom is scanned to evaluate the approach. Various interferograms with different carrier fringe frequencies are investigated and the reconstruction image quality is evaluated in terms of contrast, noise and sharpness. The results indicated that the DPC images can be effectively retrieved using the Fourier transform-based approach and the reconstructed phase coefficient showed better contrast compared to that of attenuation-based contrast. The spatial resolution is acceptable in the phantom studies although it is not as good as the results of phase-stepping approach. The Fourier transform-based phase retrieval approach is able to greatly simplify data acquisition, to improve the temporal resolution and to make it possible for dynamic DPC-CBCT imaging. It is promising for perfusion imaging where spatial resolution is not a concern. PMID:23378889

  12. White-light quantitative phase imaging unit

    NASA Astrophysics Data System (ADS)

    Baek, YoonSeok; Lee, KyeoReh; Yoon, Jonghee; Kim, Kyoohyun; Park, YongKeun

    2016-05-01

    We introduce the white light quantitative phase imaging unit (WQPIU) as a practical realization of quantitative phase imaging (QPI) on standard microscope platforms. The WQPIU is a compact stand-alone unit which measures sample induced phase delay under white-light illumination. It does not require any modification of the microscope or additional accessories for its use. The principle of the WQPIU based on lateral shearing interferometry and phase shifting interferometry provides a cost-effective and user-friendly use of QPI. The validity and capacity of the presented method are demonstrated by measuring quantitative phase images of polystyrene beads, human red blood cells, HeLa cells and mouse white blood cells. With speckle-free imaging capability due to the use of white-light illumination, the WQPIU is expected to expand the scope of QPI in biological sciences as a powerful but simple imaging tool.

  13. White-light quantitative phase imaging unit.

    PubMed

    Baek, YoonSeok; Lee, KyeoReh; Yoon, Jonghee; Kim, Kyoohyun; Park, YongKeun

    2016-05-01

    We introduce the white-light quantitative phase imaging unit (WQPIU) as a practical realization of quantitative phase imaging (QPI) on standard microscope platforms. The WQPIU is a compact stand-alone unit which measures sample induced phase delay under white-light illumination. It does not require any modification of the microscope or additional accessories for its use. The principle of the WQPIU based on lateral shearing interferometry and phase shifting interferometry provides a cost-effective and user-friendly use of QPI. The validity and capacity of the presented method are demonstrated by measuring quantitative phase images of polystyrene beads, human red blood cells, HeLa cells and mouse white blood cells. With speckle-free imaging capability due to the use of white-light illumination, the WQPIU is expected to expand the scope of QPI in biological sciences as a powerful but simple imaging tool. PMID:27137546

  14. Phase contrast imaging of cochlear soft tissue.

    SciTech Connect

    Smith, S.; Hwang, M.; Rau, C.; Fishman, A.; Lee, W.; Richter, C.

    2011-01-01

    A noninvasive technique to image soft tissue could expedite diagnosis and disease management in the auditory system. We propose inline phase contrast imaging with hard X-rays as a novel method that overcomes the limitations of conventional absorption radiography for imaging soft tissue. In this study, phase contrast imaging of mouse cochleae was performed at the Argonne National Laboratory Advanced Photon Source. The phase contrast tomographic reconstructions show soft tissue structures of the cochlea, including the inner pillar cells, the inner spiral sulcus, the tectorial membrane, the basilar membrane, and the Reissner's membrane. The results suggest that phase contrast X-ray imaging and tomographic techniques hold promise to noninvasively image cochlear structures at an unprecedented cellular level.

  15. A Synthetic Quadrature Phase Detector/Demodulator for Fourier Transform Transform Spectrometers

    NASA Technical Reports Server (NTRS)

    Campbell, Joel

    2008-01-01

    A method is developed to demodulate (velocity correct) Fourier transform spectrometer (FTS) data that is taken with an analog to digital converter that digitizes equally spaced in time. This method makes it possible to use simple low cost, high resolution audio digitizers to record high quality data without the need for an event timer or quadrature laser hardware, and makes it possible to use a metrology laser of any wavelength. The reduced parts count and simplicity implementation makes it an attractive alternative in space based applications when compared to previous methods such as the Brault algorithm.

  16. Deformation measurement of carbon fiber reinforced plastics using phase-shifting scanning electron microscope Moir method after Fourier transform

    NASA Astrophysics Data System (ADS)

    Wang, Qinghua; Ri, Shien; Tsuda, Hiroshi; Kishimoto, Satoshi; Tanaka, Yoshihisa; Kagawa, Yutaka

    2015-07-01

    The deformation distributions of carbon fiber reinforced plastics (CFRP) under a three-point bending load were nondestructively investigated using the phase shifting scanning electron microscope (SEM) moir method. The complex fast Fourier transform (FFT) and the discrete Fourier transform (DFT) were used to filter the useless moir fringes in the case of bidirectional moir fringes. The SEM moir fringes under different magnifications and the deformation results measured by the direct, complex FFT- and the DFT- phase shifting moir methods as well as the moir fringe centering method were compared and analyzed. Experiments demonstrate that the deformation measurement is a bit influenced by the useless moir fringes in the phase shifting moir methods and complex FFT processing works better for nondense moir fringes. The relative strain changes gradually and the specimen grating pitch increases gradually from top to bottom along the loading direction, suggesting that the real compressive strain is greater in the upper side. The micro/nano-scale deformation distribution characteristic is helpful for better understanding of the mechanical properties of the CFRP specimen.

  17. Coded aperture pair for quantitative phase imaging.

    PubMed

    Wu, Jiamin; Lin, Xing; Liu, Yebin; Suo, Jinli; Dai, Qionghai

    2014-10-01

    This Letter proposes a novel quantitative phase-imaging approach by optically encoding light fields into a complementary image pair followed by computational reconstruction. We demonstrate that the axial intensity derivative for phase recovery can be well estimated by a coded-aperture image pair without z axial scanning. The experimental results demonstrate that our approach can achieve higher accuracy and robustness compared with conventional transport-of-intensity equation (TIE) based approaches under partial coherence illumination. PMID:25360982

  18. Objective assessment of image quality. II. Fisher information, Fourier crosstalk, and figures of merit for task performance

    NASA Astrophysics Data System (ADS)

    Barrett, Harrison H.; Denny, J. L.; Wagner, Robert F.; Myers, Kyle J.

    1995-05-01

    Figures of merit for image quality are derived on the basis of the performance of mathematical observers on specific detection and estimation tasks. The tasks include detection of a known signal superimposed on a known background, detection of a known signal on a random background, estimation of Fourier coefficients of the object, and estimation of the integral of the object over a specified region of interest. The chosen observer for the detection tasks is the ideal linear discriminant, which we call the Hotelling observer. The figures of merit are based on the Fisher information matrix relevant to estimation of the Fourier coefficients and the closely related Fourier crosstalk matrix introduced earlier by Barrett and Gifford [Phys. Med. Biol. 39, 451 (1994)]. A finite submatrix of the infinite Fisher information matrix is used to set Cramer-Rao lower bounds on the variances of the estimates of the first N Fourier coefficients. The figures of merit for detection tasks are shown to be closely related to the concepts of noise-equivalent quanta (NEQ) and

  19. Human sensitivity to phase perturbations in natural images: a statistical framework.

    PubMed

    Thomson, M G; Foster, D H; Summers, R J

    2000-01-01

    Fourier-phase information is important in determining the appearance of natural scenes, but the structure of natural-image phase spectra is highly complex and difficult to relate directly to human perceptual processes. This problem is addressed by extending previous investigations of human visual sensitivity to the randomisation and quantisation of Fourier phase in natural images. The salience of the image changes induced by these physical processes is shown to depend critically on the nature of the original phase spectrum of each image, and the processes of randomisation and quantisation are shown to be perceptually equivalent provided that they shift image phase components by the same average amount. These results are explained by assuming that the visual system is sensitive to those phase-domain image changes which also alter certain global higher-order image statistics. This assumption may be used to place constraints on the likely nature of cortical processing: mechanisms which correlate the outputs of a bank of relative-phase-sensitive units are found to be consistent with the patterns of sensitivity reported here. PMID:11144819

  20. FPGA-based multi-channel fluorescence lifetime analysis of Fourier multiplexed frequency-sweeping lifetime imaging

    PubMed Central

    Zhao, Ming; Li, Yu; Peng, Leilei

    2014-01-01

    We report a fast non-iterative lifetime data analysis method for the Fourier multiplexed frequency-sweeping confocal FLIM (Fm-FLIM) system [ Opt. Express22, 10221 ( 2014)24921725]. The new method, named R-method, allows fast multi-channel lifetime image analysis in the system’s FPGA data processing board. Experimental tests proved that the performance of the R-method is equivalent to that of single-exponential iterative fitting, and its sensitivity is well suited for time-lapse FLIM-FRET imaging of live cells, for example cyclic adenosine monophosphate (cAMP) level imaging with GFP-Epac-mCherry sensors. With the R-method and its FPGA implementation, multi-channel lifetime images can now be generated in real time on the multi-channel frequency-sweeping FLIM system, and live readout of FRET sensors can be performed during time-lapse imaging. PMID:25321778

  1. From regular text to artistic writing and artworks: Fourier statistics of images with low and high aesthetic appeal

    PubMed Central

    Melmer, Tamara; Amirshahi, Seyed A.; Koch, Michael; Denzler, Joachim; Redies, Christoph

    2013-01-01

    The spatial characteristics of letters and their influence on readability and letter identification have been intensely studied during the last decades. There have been few studies, however, on statistical image properties that reflect more global aspects of text, for example properties that may relate to its aesthetic appeal. It has been shown that natural scenes and a large variety of visual artworks possess a scale-invariant Fourier power spectrum that falls off linearly with increasing frequency in log-log plots. We asked whether images of text share this property. As expected, the Fourier spectrum of images of regular typed or handwritten text is highly anisotropic, i.e., the spectral image properties in vertical, horizontal, and oblique orientations differ. Moreover, the spatial frequency spectra of text images are not scale-invariant in any direction. The decline is shallower in the low-frequency part of the spectrum for text than for aesthetic artworks, whereas, in the high-frequency part, it is steeper. These results indicate that, in general, images of regular text contain less global structure (low spatial frequencies) relative to fine detail (high spatial frequencies) than images of aesthetics artworks. Moreover, we studied images of text with artistic claim (ornate print and calligraphy) and ornamental art. For some measures, these images assume average values intermediate between regular text and aesthetic artworks. Finally, to answer the question of whether the statistical properties measured by us are universal amongst humans or are subject to intercultural differences, we compared images from three different cultural backgrounds (Western, East Asian, and Arabic). Results for different categories (regular text, aesthetic writing, ornamental art, and fine art) were similar across cultures. PMID:23554592

  2. System design of Fourier transform imaging spectrometer using tunable lateral shearing splitter

    NASA Astrophysics Data System (ADS)

    Meng, Xin; Li, Jianxin; Bai, Caixun; Zhu, Rihong

    2015-04-01

    The Fourier transform spectrometer without slit has the advantages of high radiation throughput and high spatial resolution. It can be used for detecting more details of the spectral and spatial information. We present the initial structure of the collimator and objective based on the analysis of the principle of the Fourier transform spectrometer. Then the collimator and objective are optimized by Zemax. The MTF of the cut-off frequency is great than 0.7. The tunable lateral shearing splitter is used as the interferometer, which makes the system more compact compared with the system using Sagnac lateral shearing splitter. The method to calculate the geometric dimension of the splitter is presented. Then the complete Fourier transform spectrometer is designed. The MTF of the cut-off frequency is great than 0.6. And the largest RMS of the spot is less than 6μm.

  3. A Panchromatic Imaging Fourier Transform Spectrometer for the NASA Geostationary Coastal and Air Pollution Events Mission

    NASA Technical Reports Server (NTRS)

    Wu, Yen-Hung; Key, Richard; Sander, Stanley; Blavier, Jean-Francois; Rider, David

    2011-01-01

    This paper summarizes the design and development of the Panchromatic Imaging Fourier Transform Spectrometer (PanFTS) for the NASA Geostationary Coastal and Air Pollution Events (GEO-CAPE) Mission. The PanFTS instrument will advance the understanding of the global climate and atmospheric chemistry by measuring spectrally resolved outgoing thermal and reflected solar radiation. With continuous spectral coverage from the near-ultraviolet through the thermal infrared, this instrument is designed to measure pollutants, greenhouse gases, and aerosols as called for by the U.S. National Research Council Decadal Survey; Earth Science and Applications from Space: National Imperatives for the Next Decade and Beyond1. The PanFTS instrument is a hybrid instrument based on spectrometers like the Tropospheric Emissions Spectrometer (TES) that measures thermal emission, and those like the Orbiting Carbon Observatory (OCO), and the Ozone Monitoring Instrument (OMI) that measure scattered solar radiation. Simultaneous measurements over the broad spectral range from IR to UV is accomplished by a two sided interferometer with separate optical trains and detectors for the ultraviolet-visible and infrared spectral domains. This allows each side of the instrument to be independently optimized for its respective spectral domain. The overall interferometer design is compact because the two sides share a single high precision cryogenic optical path difference mechanism (OPDM) and metrology laser as well as a number of other instrument systems including the line-of-sight pointing mirror, the data management system, thermal control system, electrical system, and the mechanical structure. The PanFTS breadboard instrument has been tested in the laboratory and demonstrated the basic functionality for simultaneous measurements in the visible and infrared. It is set to begin operations in the field at the California Laboratory for Atmospheric Remote Sensing (CLARS) observatory on Mt. Wilson measuring the atmospheric chemistry across the Los Angeles basin. Development has begun on a flight size PanFTS engineering model (EM) that addresses all critical scaling issues and demonstrates operation over the full spectral range of the flight instrument which will show the PanFTS instrument design is mature.

  4. Mitochondrial dynamics and optical conformation changes in DsRed as studied by Fourier imaging correlation spectroscopy

    NASA Astrophysics Data System (ADS)

    Senning, Eric Nicolas

    Novel experiments that probe the dynamics of intracellular species, including the center-of-mass displacements and internal conformational transitions of biological macromolecules, have the potential to reveal the complex biochemical mechanisms operating within the cell. This work presents the implementation and development of Fourier imaging correlation spectroscopy (FICS), a phase-selective approach to fluorescence spectroscopy that measures the collective coordinate fluctuations of fluorescently labeled microscopic particles. In FICS experiments, a spatially modulated optical grating excites a fluorescently labeled sample. Phase-synchronous detection of the fluorescence, with respect to the phase of the exciting optical grating, can be used to monitor the fluctuations of partially averaged spatial coordinates. These data are then analyzed by two-point and four-point time correlation functions to provide a statistically meaningful understanding of the dynamics under observation. FICS represents a unique route to elevate signal levels, while acquiring detailed information about molecular coordinate trajectories. Mitochondria of mammalian cells are known to associate with cytoskeletal proteins, and their motions are affected by the stability of microtubules and microfilaments. Within the cell it is possible to fluorescently label the mitochondria and study its dynamic behavior with FICS. The dynamics of S. cerevisiae yeast mitochondria are characterized at four discrete length scales (ranging from 0.6--1.19 mum) and provide detailed information about the influence of specific cytoskeletal elements. Using the microtubule and microfilament destabilizing agents, Nocodazole and Latrunculin A, it is determined that microfilaments are required for normal yeast mitochondrial motion while microtubules have no effect. Experiments with specific actin mutants revealed that actin is responsible for enhanced mobility on length scales greater than 0.6 mum. The versatility of FICS expands when individual molecules are labeled with fluorescent chromophores. In recent experiments on the tetrameric fluorescent protein DsRed, polarization-modulated FICS (PM-FICS) is demonstrated to separate conformational dynamics from molecular translational dynamics. The optical switching pathways of DsRed, a tetrameric complex of fluorescent protein subunits, are examined. An analysis of PM-FICS coordinate trajectories, in terms of 2D spectra and joint probability distributions, provides detailed information about the transition pathways between distinct dipole-coupled DsRed conformations. This dissertation includes co-authored and previously published material.

  5. Single-shot X-ray phase-contrast imaging using two-dimensional gratings

    SciTech Connect

    Sato, Genta; Itoh, Hidenosuke; Nagai, Kentaro; Nakamura, Takashi; Yamaguchi, Kimiaki; Kondoh, Takeshi; Handa, Soichiro; Ouchi, Chidane; Teshima, Takayuki; Setomoto, Yutaka; Den, Toru

    2012-07-31

    We developed a two-dimensional gratings-based X-ray interferometer that requires only a single exposure for clinical radiography. The interferometer consisted of a checkerboard phase grating for {pi} phase modulation and a latticed amplitude grating. Using a synchrotron radiation source, the phase grating modulates the X-rays and generates a self-image, transformed to a moire fringe by the amplitude grating. To allow use of a conventional X-ray tube, the latticed source grating was installed downstream from the X-ray tube. Differential phase-contrast and scattering images in two orthogonal directions were obtained by Fourier analysis of the single moire fringe image and an absorption image. Results show that characteristic features of soft tissue in two orthogonal directions were clearly shown in the differential phase-contrast images.

  6. Symmetric Phase-Only Filtering in Particle-Image Velocimetry

    NASA Technical Reports Server (NTRS)

    Wemet, Mark P.

    2008-01-01

    Symmetrical phase-only filtering (SPOF) can be exploited to obtain substantial improvements in the results of data processing in particle-image velocimetry (PIV). In comparison with traditional PIV data processing, SPOF PIV data processing yields narrower and larger amplitude correlation peaks, thereby providing more-accurate velocity estimates. The higher signal-to-noise ratios associated with the higher amplitude correlation peaks afford greater robustness and reliability of processing. SPOF also affords superior performance in the presence of surface flare light and/or background light. SPOF algorithms can readily be incorporated into pre-existing algorithms used to process digitized image data in PIV, without significantly increasing processing times. A summary of PIV and traditional PIV data processing is prerequisite to a meaningful description of SPOF PIV processing. In PIV, a pulsed laser is used to illuminate a substantially planar region of a flowing fluid in which particles are entrained. An electronic camera records digital images of the particles at two instants of time. The components of velocity of the fluid in the illuminated plane can be obtained by determining the displacements of particles between the two illumination pulses. The objective in PIV data processing is to compute the particle displacements from the digital image data. In traditional PIV data processing, to which the present innovation applies, the two images are divided into a grid of subregions and the displacements determined from cross-correlations between the corresponding sub-regions in the first and second images. The cross-correlation process begins with the calculation of the Fourier transforms (or fast Fourier transforms) of the subregion portions of the images. The Fourier transforms from the corresponding subregions are multiplied, and this product is inverse Fourier transformed, yielding the cross-correlation intensity distribution. The average displacement of the particles across a subregion results in a displacement of the correlation peak from the center of the correlation plane. The velocity is then computed from the displacement of the correlation peak and the time between the recording of the two images. The process as described thus far is performed for all the subregions. The resulting set of velocities in grid cells amounts to a velocity vector map of the flow field recorded on the image plane. In traditional PIV processing, surface flare light and bright background light give rise to a large, broad correlation peak, at the center of the correlation plane, that can overwhelm the true particle- displacement correlation peak. This has made it necessary to resort to tedious image-masking and background-subtraction procedures to recover the relatively small amplitude particle-displacement correlation peak. SPOF is a variant of phase-only filtering (POF), which, in turn, is a variant of matched spatial filtering (MSF). In MSF, one projects a first image (denoted the input image) onto a second image (denoted the filter) as part of a computation to determine how much and what part of the filter is present in the input image. MSF is equivalent to cross-correlation. In POF, the frequency-domain content of the MSF filter is modified to produce a unitamplitude (phase-only) object. POF is implemented by normalizing the Fourier transform of the filter by its magnitude. The advantage of POFs is that they yield correlation peaks that are sharper and have higher signal-to-noise ratios than those obtained through traditional MSF. In the SPOF, these benefits of POF can be extended to PIV data processing. The SPOF yields even better performance than the POF approach, which is uniquely applicable to PIV type image data. In SPOF as now applied to PIV data processing, a subregion of the first image is treated as the input image and the corresponding subregion of the second image is treated as the filter. The Fourier transforms from both the firs and second- image subregions are normalized by the square roots of their respective magnitudes. This scheme yields optimal performance because the amounts of normalization applied to the spatial-frequency contents of the input and filter scenes are just enough to enhance their high-spatial-frequency contents while reducing their spurious low-spatial-frequency content. As a result, in SPOF PIV processing, particle-displacement correlation peaks can readily be detected above spurious background peaks, without need for masking or background subtraction.

  7. Quantitative-phase-contrast imaging of a two-level surface described as a 2D linear filtering process.

    PubMed

    Lovicar, Luděk; Komrska, Jiří; Chmelík, Radim

    2010-09-27

    The paper deals with quantitative phase imaging of two-height-level surface reliefs. The imaging is considered to be a linear system and, consequently, the Fourier transform of the image is the product of the Fourier transform of a 2D function characterizing the surface and a specific 2D coherent transfer function. The Fourier transform of functions specifying periodic surface reliefs is factorized into two functions similar to lattice and structure amplitudes in crystal structure analysis. The approach to the imaging process described in the paper enables us to examine the dependence of the phase image on the surface geometry. Theoretical results are verified experimentally by means of a digital holographic microscope. PMID:20940953

  8. Phase-resolved optical frequency domain imaging

    NASA Astrophysics Data System (ADS)

    Vakoc, B. J.; Yun, S. H.; de Boer, J. F.; Tearney, G. J.; Bouma, B. E.

    2005-07-01

    Phase-resolved Doppler optical coherence tomography has been used to image blood flow dynamics in various tissues using both time-domain and spectral-domain optical coherence tomography techniques. In this manuscript, we present phase-resolved Doppler imaging with a high-speed optical frequency domain imaging system. We demonstrate that by correcting for spurious timing-induced phase errors, excellent flow sensitivity can be achieved, limited only by the imaging signal-to-noise ratio. Conventional and Doppler images showing flow in an Intralipid phantom and in human skin are presented. Additionally, we demonstrate the ability of phase-resolved OFDI to measure high flow rates without the deleterious effects of fringe washout.

  9. Phase-resolved optical frequency domain imaging.

    PubMed

    Vakoc, B; Yun, S; de Boer, J; Tearney, G; Bouma, B

    2005-07-11

    Phase-resolved Doppler optical coherence tomography has been used to image blood flow dynamics in various tissues using both time-domain and spectral-domain optical coherence tomography techniques. In this manuscript, we present phase-resolved Doppler imaging with a high-speed optical frequency domain imaging system. We demonstrate that by correcting for spurious timing-induced phase errors, excellent flow sensitivity can be achieved, limited only by the imaging signal-to-noise ratio. Conventional and Doppler images showing flow in an Intralipid phantom and in human skin are presented. Additionally, we demonstrate the ability of phase-resolved OFDI to measure high flow rates without the deleterious effects of fringe washout. PMID:19498543

  10. Phase and TV Based Convex Sets for Blind Deconvolution of Microscopic Images

    NASA Astrophysics Data System (ADS)

    Tofighi, Mohammad; Yorulmaz, Onur; Kose, Kivanc; Yildirim, Deniz Cansen; Cetin-Atalay, Rengul; Cetin, A. Enis

    2016-02-01

    In this article, two closed and convex sets for blind deconvolution problem are proposed. Most blurring functions in microscopy are symmetric with respect to the origin. Therefore, they do not modify the phase of the Fourier transform (FT) of the original image. As a result blurred image and the original image have the same FT phase. Therefore, the set of images with a prescribed FT phase can be used as a constraint set in blind deconvolution problems. Another convex set that can be used during the image reconstruction process is the epigraph set of Total Variation (TV) function. This set does not need a prescribed upper bound on the total variation of the image. The upper bound is automatically adjusted according to the current image of the restoration process. Both of these two closed and convex sets can be used as a part of any blind deconvolution algorithm. Simulation examples are presented.

  11. Flexible Retrospective Phase Stepping in X-Ray Scatter Correction and Phase Contrast Imaging Using Structured Illumination

    PubMed Central

    Wen, Han; Miao, Houxun; Bennett, Eric E.; Adamo, Nick M.; Chen, Lei

    2013-01-01

    The development of phase contrast methods for diagnostic x-ray imaging is inspired by the potential of seeing the internal structures of the human body without the need to deposit any harmful radiation. An efficient class of x-ray phase contrast imaging and scatter correction methods share the idea of using structured illumination in the form of a periodic fringe pattern created with gratings or grids. They measure the scatter and distortion of the x-ray wavefront through the attenuation and deformation of the fringe pattern via a phase stepping process. Phase stepping describes image acquisition at regular phase intervals by shifting a grating in uniform steps. However, in practical conditions the actual phase intervals can vary from step to step and also spatially. Particularly with the advent of electromagnetic phase stepping without physical movement of a grating, the phase intervals are dependent upon the focal plane of interest. We describe a demodulation algorithm for phase stepping at arbitrary and position-dependent (APD) phase intervals without assuming a priori knowledge of the phase steps. The algorithm retrospectively determines the spatial distribution of the phase intervals by a Fourier transform method. With this ability, grating-based x-ray imaging becomes more adaptable and robust for broader applications. PMID:24205177

  12. Fourier planes vs. Scheimpflug principle in microscopic and scatterometric devices

    NASA Astrophysics Data System (ADS)

    Hahlweg, Cornelius; Zhao, Wenjing; Rothe, Hendrik

    2011-10-01

    The present paper is understood as a continuation of our paper on the utilization of the Scheimpflug-principle in scatterometric devices. Imaging scatterometers in principle gather the fourier image of the illuminated spot, which in microscopy would be the primary diffraction image. Therefore imaging scatterometers can be used as microscopes as well, which only requires an additional positive lens or equivalent mirror. It is obvious that combined designs are interesting in surface inspection: because of the loss of phase information in both direct and scatter image, there is still non redundant information besides the intersection set of both images. For the design of such combined devices it is of high interest to identify the fourier images. While a more or less paraxial dioptric device in orthogonal view has well defined fourier planes, in an off axis device with paraboloid or elliptical mirrors the fourier image is concerned by the Scheimpflug relations, which shall be subject of the present paper.

  13. Nonlinear ultrasonic phased array imaging.

    PubMed

    Potter, J N; Croxford, A J; Wilcox, P D

    2014-10-01

    This Letter reports a technique for the imaging of acoustic nonlinearity. By contrasting the energy of the diffuse field produced through the focusing of an ultrasonic array by delayed parallel element transmission with that produced by postprocessing of sequential transmission data, acoustic nonlinearity local to the focal point is measured. Spatially isolated wave distortion is inferred without requiring interrogation of the wave at the inspection point, thereby allowing nonlinear imaging through depth. PMID:25325647

  14. High-definition Fourier Transform Infrared (FT-IR) Spectroscopic Imaging of Human Tissue Sections towards Improving Pathology

    PubMed Central

    Nguyen, Peter L.; Davidson, Bennett; Akkina, Sanjeev; Guzman, Grace; Setty, Suman; Kajdacsy-Balla, Andre; Walsh, Michael J.

    2015-01-01

    High-definition Fourier Transform Infrared (FT-IR) spectroscopic imaging is an emerging approach to obtain detailed images that have associated biochemical information. FT-IR imaging of tissue is based on the principle that different regions of the mid-infrared are absorbed by different chemical bonds (e.g., C=O, C-H, N-H) within cells or tissue that can then be related to the presence and composition of biomolecules (e.g., lipids, DNA, glycogen, protein, collagen). In an FT-IR image, every pixel within the image comprises an entire Infrared (IR) spectrum that can give information on the biochemical status of the cells that can then be exploited for cell-type or disease-type classification. In this paper, we show: how to obtain IR images from human tissues using an FT-IR system, how to modify existing instrumentation to allow for high-definition imaging capabilities, and how to visualize FT-IR images. We then present some applications of FT-IR for pathology using the liver and kidney as examples. FT-IR imaging holds exciting applications in providing a novel route to obtain biochemical information from cells and tissue in an entirely label-free non-perturbing route towards giving new insight into biomolecular changes as part of disease processes. Additionally, this biochemical information can potentially allow for objective and automated analysis of certain aspects of disease diagnosis. PMID:25650759

  15. Quantitative phase imaging using grating-based quadrature phase interferometer

    NASA Astrophysics Data System (ADS)

    Wu, Jigang; Yaqoob, Zahid; Heng, Xin; Cui, Xiquan; Yang, Changhuei

    2007-02-01

    In this paper, we report the use of holographic gratings, which act as the free-space equivalent of the 3x3 fiber-optic coupler, to perform full field phase imaging. By recording two harmonically-related gratings in the same holographic plate, we are able to obtain nontrivial phase shift between different output ports of the gratings-based Mach-Zehnder interferometer. The phase difference can be adjusted by changing the relative phase of the recording beams when recording the hologram. We have built a Mach-Zehnder interferometer using harmonically-related holographic gratings with 600 and 1200 lines/mm spacing. Two CCD cameras at the output ports of the gratings-based Mach-Zehnder interferometer are used to record the full-field quadrature interferograms, which are subsequently processed to reconstruct the phase image. The imaging system has ~12X magnification with ~420μmx315μm field-of-view. To demonstrate the capability of our system, we have successfully performed phase imaging of a pure phase object and a paramecium caudatum.

  16. A general theoretical formalism for X-ray phase contrast imaging.

    PubMed

    Wu, Xizeng; Liu, Hong

    2003-01-01

    The in-line phase-contrast imaging has great potential for clinical imaging applications. This work presents a general theoretical formalism for the in-line phase-contrast imaging. The theoretical formalism developed in this work is derived by taking a new strategy to calculate the Fourier transform of image intensity directly. Different from the transport of intensity equation (TIE) formalism for phase-contrast imaging in literature [6], this general formalism covers both the near field regime and the holography regime of phase-contrast imaging. The image intensity formulas have been derived in both the image space and frequency space. Especially our results show that the Fresnel diffraction image intensity is a sum of convolutions of the cosine- and sine-Fresnel filters with the object attenuation A20(x) and attenuated phase A20(x)φ(x), respectively. The Pogany-Gao-Wilkins (PGW) formalism is recovered as a special case of our general formalism. In addition, in the low-resolution approximation, the general formula is reduced a spherical wave-generalization of the TIE-based formula for phase-contrast imaging. This spherical wave-generalization will be useful for phase-contrast imaging with a micro-focus x-ray tube. The transition of the formalism from 1-D to 2-D cases has been provided as well. PMID:22388096

  17. Pupil-resizing Fourier ptychography

    NASA Astrophysics Data System (ADS)

    Xie, Zongliang; Ma, Haotong; Qi, Bo; Ren, Ge; Tan, Yufeng; Zeng, Hengliang; Jiang, Chuan

    2015-11-01

    We present a coherent approach of complex amplitude reconstruction, termed aperture-resizing Fourier ptychography (FP). The reported approach resizes the pupil size of an imaging system and captures the corresponding intensity images. The acquired images are then synthesized in the frequency domain via iteration computation to reconstruct a complex sample wavefront without known phase information and interferential optics. Like holography, it is capable of reconstructing all information of the object. The reported aperture-resizing FP may find wide applications in 3D refocusing, 3D object tracking, remote sensing and microscopy.

  18. Coherent array imaging using phased subarrays

    NASA Astrophysics Data System (ADS)

    Johnson, Jeremy Aaron

    This research was motivated by the need to reduce the front-end hardware complexity of 3D ultrasound imaging systems using 2D transducer arrays. The results apply to other coherent array imaging applications including sonar, radio astronomy, and seismic imaging. Conventional full phased array (FPA) imaging requires parallel front-end electronic hardware to process the signals from each element independently. While currently used for commercial 2D ultrasound imaging using 1D transducer arrays, FPA imaging does not scale well to 3D imaging due to the overwhelming number of transducer elements. Phased subarray (PSA) imaging has been proposed as a method to reduce the imaging system's front-end hardware complexity while achieving near-FPA image quality. Each scan line is formed using multiple subsets of adjacent elements---subarrays---that span the full array. PSA imaging reduces the number of front-end hardware channels to the number of elements in the subarray. This dissertation extends the capabilities of PSA imaging. A mathematical model of the imaging response in the spatial domain and spatial frequency domain, or k-space, is developed for PSA imaging. This model is used as the basis for two new methods of designing subarray reconstruction filters for wideband PSA imaging. PSA and FPA imaging are compared using experimental data for 2D imaging and simulated data for 3D imaging. Experimental images were formed of a wire phantom using a 128-element capacitive micromachined ultrasound transducer array. PSA imaging had little or no affect on the axial resolution and little or no effect on the lateral resolution within the focal region. The SNR of the PSA images was slightly lower than that of the FPA images when using 32-element subarrays, and decreased for smaller subarrays. The contrast-to-noise ratio of PSA and FPA imaging was compared using simulated pulse-echo data of a cyst phantom and was slightly lower for all PSA imaging methods. The results illustrate that PSA imaging reduces the front-end hardware complexity and can enable real-time 3D ultrasound imaging.

  19. Optical imaging with phase-coded aperture.

    PubMed

    Chi, Wanli; George, Nicholas

    2011-02-28

    Experimental results are shown for an integrated computational imaging system with a phase-coded aperture. A spatial light modulator works as a phase screen that diffracts light from a point object into a uniformly redundant array (URA). Excellent imaging results are achieved after correlation processing. The system has the same depth of field as a diffraction-limited lens. Potential applications are discussed. PMID:21369259

  20. Image Display and Manipulation System (IDAMS) program documentation, Appendixes A-D. [including routines, convolution filtering, image expansion, and fast Fourier transformation

    NASA Technical Reports Server (NTRS)

    Cecil, R. W.; White, R. A.; Szczur, M. R.

    1972-01-01

    The IDAMS Processor is a package of task routines and support software that performs convolution filtering, image expansion, fast Fourier transformation, and other operations on a digital image tape. A unique task control card for that program, together with any necessary parameter cards, selects each processing technique to be applied to the input image. A variable number of tasks can be selected for execution by including the proper task and parameter cards in the input deck. An executive maintains control of the run; it initiates execution of each task in turn and handles any necessary error processing.

  1. Multifocus image fusion using phase congruency

    NASA Astrophysics Data System (ADS)

    Zhan, Kun; Li, Qiaoqiao; Teng, Jicai; Wang, Mingying; Shi, Jinhui

    2015-05-01

    We address the problem of fusing multifocus images based on the phase congruency (PC). PC provides a sharpness feature of a natural image. The focus measure (FM) is identified as strong PC near a distinctive image feature evaluated by the complex Gabor wavelet. The PC is more robust against noise than other FMs. The fusion image is obtained by a new fusion rule (FR), and the focused region is selected by the FR from one of the input images. Experimental results show that the proposed fusion scheme achieves the fusion performance of the state-of-the-art methods in terms of visual quality and quantitative evaluations.

  2. Phase contrast portal imaging using synchrotron radiation

    NASA Astrophysics Data System (ADS)

    Umetani, K.; Kondoh, T.

    2014-07-01

    Microbeam radiation therapy is an experimental form of radiation treatment with great potential to improve the treatment of many types of cancer. We applied a synchrotron radiation phase contrast technique to portal imaging to improve targeting accuracy for microbeam radiation therapy in experiments using small animals. An X-ray imaging detector was installed 6.0 m downstream from an object to produce a high-contrast edge enhancement effect in propagation-based phase contrast imaging. Images of a mouse head sample were obtained using therapeutic white synchrotron radiation with a mean beam energy of 130 keV. Compared to conventional portal images, remarkably clear images of bones surrounding the cerebrum were acquired in an air environment for positioning brain lesions with respect to the skull structure without confusion with overlapping surface structures.

  3. Phase contrast portal imaging using synchrotron radiation

    SciTech Connect

    Umetani, K.; Kondoh, T.

    2014-07-15

    Microbeam radiation therapy is an experimental form of radiation treatment with great potential to improve the treatment of many types of cancer. We applied a synchrotron radiation phase contrast technique to portal imaging to improve targeting accuracy for microbeam radiation therapy in experiments using small animals. An X-ray imaging detector was installed 6.0 m downstream from an object to produce a high-contrast edge enhancement effect in propagation-based phase contrast imaging. Images of a mouse head sample were obtained using therapeutic white synchrotron radiation with a mean beam energy of 130 keV. Compared to conventional portal images, remarkably clear images of bones surrounding the cerebrum were acquired in an air environment for positioning brain lesions with respect to the skull structure without confusion with overlapping surface structures.

  4. Phase imaging in brain using SWIFT

    PubMed Central

    Lehto, Lauri Juhani; Garwood, Michael; Gröhn, Olli; Corum, Curtis Andrew

    2015-01-01

    The majority of MRI phase imaging is based on gradient recalled echo (GRE) sequences. This work studies phase contrast behavior due to small off-resonance frequency offsets in brain using SWIFT, a FID-based sequence with nearly zero acquisition delay. 1D simulations and a phantom study were conducted to describe the behavior of phase accumulation in SWIFT. Imaging experiments of known brain phase contrast properties were conducted in a perfused rat brain comparing GRE and SWIFT. Additionally, a human brain sample was imaged. It is demonstrated how SWIFT phase is orientation dependent and correlates well with GRE, linking SWIFT phase to similar off-resonance sources as GRE. The acquisition time is shown to be analogous to TE for phase accumulation time. Using experiments with and without a magnetization transfer preparation, the likely effect of myelin water pool contribution is seen as a phase increase for all acquisition times. Due to the phase accumulation during acquisition, SWIFT phase contrast can be sensitized to small frequency differences between white and gray matter using low acquisition bandwidths. PMID:25625826

  5. Phase imaging in brain using SWIFT.

    PubMed

    Lehto, Lauri Juhani; Garwood, Michael; Gröhn, Olli; Corum, Curtis Andrew

    2015-03-01

    The majority of MRI phase imaging is based on gradient recalled echo (GRE) sequences. This work studies phase contrast behavior due to small off-resonance frequency offsets in brain using SWIFT, a FID-based sequence with nearly zero acquisition delay. 1D simulations and a phantom study were conducted to describe the behavior of phase accumulation in SWIFT. Imaging experiments of known brain phase contrast properties were conducted in a perfused rat brain comparing GRE and SWIFT. Additionally, a human brain sample was imaged. It is demonstrated how SWIFT phase is orientation dependent and correlates well with GRE, linking SWIFT phase to similar off-resonance sources as GRE. The acquisition time is shown to be analogous to TE for phase accumulation time. Using experiments with and without a magnetization transfer preparation, the likely effect of myelin water pool contribution is seen as a phase increase for all acquisition times. Due to the phase accumulation during acquisition, SWIFT phase contrast can be sensitized to small frequency differences between white and gray matter using low acquisition bandwidths. PMID:25625826

  6. Phase imaging in brain using SWIFT

    NASA Astrophysics Data System (ADS)

    Lehto, Lauri Juhani; Garwood, Michael; Gröhn, Olli; Corum, Curtis Andrew

    2015-03-01

    The majority of MRI phase imaging is based on gradient recalled echo (GRE) sequences. This work studies phase contrast behavior due to small off-resonance frequency offsets in brain using SWIFT, a FID-based sequence with nearly zero acquisition delay. 1D simulations and a phantom study were conducted to describe the behavior of phase accumulation in SWIFT. Imaging experiments of known brain phase contrast properties were conducted in a perfused rat brain comparing GRE and SWIFT. Additionally, a human brain sample was imaged. It is demonstrated how SWIFT phase is orientation dependent and correlates well with GRE, linking SWIFT phase to similar off-resonance sources as GRE. The acquisition time is shown to be analogous to TE for phase accumulation time. Using experiments with and without a magnetization transfer preparation, the likely effect of myelin water pool contribution is seen as a phase increase for all acquisition times. Due to the phase accumulation during acquisition, SWIFT phase contrast can be sensitized to small frequency differences between white and gray matter using low acquisition bandwidths.

  7. Genetic Algorithm Phase Retrieval for the Systematic Image-Based Optical Alignment Testbed

    NASA Technical Reports Server (NTRS)

    Taylor, Jaime; Rakoczy, John; Steincamp, James

    2003-01-01

    Phase retrieval requires calculation of the real-valued phase of the pupil fimction from the image intensity distribution and characteristics of an optical system. Genetic 'algorithms were used to solve two one-dimensional phase retrieval problem. A GA successfully estimated the coefficients of a polynomial expansion of the phase when the number of coefficients was correctly specified. A GA also successfully estimated the multiple p h e s of a segmented optical system analogous to the seven-mirror Systematic Image-Based Optical Alignment (SIBOA) testbed located at NASA s Marshall Space Flight Center. The SIBOA testbed was developed to investigate phase retrieval techniques. Tiphilt and piston motions of the mirrors accomplish phase corrections. A constant phase over each mirror can be achieved by an independent tip/tilt correction: the phase Conection term can then be factored out of the Discrete Fourier Tranform (DFT), greatly reducing computations.

  8. Level 0 to 1 processing of the imaging Fourier transform spectrometer GLORIA: generation of radiometrically and spectrally calibrated spectra

    NASA Astrophysics Data System (ADS)

    Kleinert, A.; Friedl-Vallon, F.; Guggenmoser, T.; Höpfner, M.; Neubert, T.; Ribalda, R.; Sha, M. K.; Ungermann, J.; Blank, J.; Ebersoldt, A.; Kretschmer, E.; Latzko, T.; Oelhaf, H.; Olschewski, F.; Preusse, P.

    2014-03-01

    The Gimballed Limb Observer for Radiance Imaging of the Atmosphere (GLORIA) is an imaging Fourier transform spectrometer that is capable of operating on various high altitude research aircraft. It measures the atmospheric emission in the thermal infrared spectral region in limb and nadir geometry. GLORIA consists of a classical Michelson interferometer combined with an infrared camera. The infrared detector has a usable range of 128 × 128 pixels, measuring up to 16 384 interferograms simultaneously. Imaging Fourier transform spectrometers impose a number of challenges with respect to instrument calibration and algorithm development. The innovative optical setup with extremely high optical throughput requires the development of new methods and algorithms for spectral and radiometric calibration. Due to the vast amount of data there is a high demand for scientifically intelligent optimisation of the data processing. This paper outlines the characterisation and processing steps required for the generation of radiometrically and spectrally calibrated spectra. Methods for performance optimisation of the processing algorithm are presented. The performance of the data processing and the quality of the calibrated spectra are demonstrated for measurements collected during the first deployments of GLORIA on aircraft.

  9. Phase correction of Fourier transform ion cyclotron resonance mass spectra using MatLab.

    PubMed

    Qi, Yulin; Thompson, Christopher J; Van Orden, Steve L; O'Connor, Peter B

    2011-01-01

    FT-ICR mass spectrometry has been limited to magnitude mode for almost 40 years due to the data processing methods used. However, it is well known that phase correction of the data can theoretically produce an absorption-mode spectrum with a mass-resolving power that is as much as twice as high as conventional magnitude mode, and that it also improves the quality of the peak shape. Temporally dispersed frequency sweep excitation followed by a time delay before detection results in a steep quadratic variation in the signal phase with frequency. Viewing this, it is possible to find the correct phase function by performing a quadratic least squares fit, modified by iterating through phase cycles until the correct quadratic function is found. Here, we present a robust manual method to rotate these signals mathematically and generate a "phased" absorption-mode spectrum. The method can, in principle, be automated. Baseline correction is also included to eliminate the accompanying baseline drift. The resulting experimental FT-ICR absorption-mode spectra exhibit a resolving power that is at least 50% higher than that of the magnitude mode. PMID:21472552

  10. Microsolvation of reactive systems in the gas phase via Fourier transform microwave spectroscopy

    NASA Astrophysics Data System (ADS)

    Brauer, Carolyn Sue

    Fourier transform microwave spectroscopy has been used to study a number of reactive systems, with the primary goal of probing the effects of solvent on a molecule or a weakly bound acid-base system at the small cluster level. Because these systems are particularly sensitive to their first, nearest neighbors, the studies focus on examining structural changes and electronic rearrangement that occurs with the addition of a single solvent molecule, or microsolvent. The structural effects of microsolvation were examined on two prototypical acid-base systems. The first sought to ascertain the effect of microsolvent polarity by microsolvating HCN-SO3 with Ar and CO, forming the complexes HCN-SO3···Ar and HCN-SO 3···CO. Dipole moments and ab initio calculations also are reported. The second examined the effect of microsolvation on the primary hydrogen bond distance of (CH3)3N···HF, by adding a single HF molecule, forming the complex (CH3) 3N···HF···HF. The Stark effect was measured on a series of hydrogen halide complexes. These systems are prototypical complexes with which to study proton transfer across a hydrogen bond. The resulting dipole moments are discussed in terms of the degree of proton transfer. The dipole moment also was determined for the H2SO4···H 2O complex, which provides an important model system for understanding rates of binary homogeneous nucleation, and a series of ab initio calculations were performed in support of the results. Finally, the microwave spectrum of the radical complex OH-H2O was observed and analyzed using a two-state model which accounts for nuclear motion on the 2A' and 2A" potential surfaces. The results provide insights into the effects of the partial quenching of orbital angular momentum.

  11. Optical character recognition of camera-captured images based on phase features

    NASA Astrophysics Data System (ADS)

    Diaz-Escobar, Julia; Kober, Vitaly

    2015-09-01

    Nowadays most of digital information is obtained using mobile devices specially smartphones. In particular, it brings the opportunity for optical character recognition in camera-captured images. For this reason many recognition applications have been recently developed such as recognition of license plates, business cards, receipts and street signal; document classification, augmented reality, language translator and so on. Camera-captured images are usually affected by geometric distortions, nonuniform illumination, shadow, noise, which make difficult the recognition task with existing systems. It is well known that the Fourier phase contains a lot of important information regardless of the Fourier magnitude. So, in this work we propose a phase-based recognition system exploiting phase-congruency features for illumination/scale invariance. The performance of the proposed system is tested in terms of miss classifications and false alarms with the help of computer simulation.

  12. Ultrahigh-speed imaging of the rat retina using ultrahigh-resolution spectral/Fourier domain OCT

    NASA Astrophysics Data System (ADS)

    Liu, Jonathan J.; Potsaid, Benjamin; Chen, Yueli; Gorczynska, Iwona; Srinivasan, Vivek J.; Duker, Jay S.; Fujimoto, James G.

    2010-02-01

    We performed OCT imaging of the rat retina at 70,000 axial scans per second with ~3 μm axial resolution. Three-dimensional OCT (3D-OCT) data sets of the rat retina were acquired. The high speed and high density data sets enable improved en face visualization by reducing eye motion artifacts and improve Doppler OCT measurements. Minimal motion artifacts were visible and the OCT fundus images offer more precise registration of individual OCT images to retinal fundus features. Projection OCT fundus images show features such as the nerve fiber layer, retinal capillary networks and choroidal vasculature. Doppler OCT images and quantitative measurements show pulsatility in retinal blood vessels. Doppler OCT provides noninvasive in vivo quantitative measurements of retinal blood flow properties and may benefit studies of diseases such as glaucoma and diabetic retinopathy. Ultrahigh speed imaging using ultrahigh resolution spectral / Fourier domain OCT promises to enable novel protocols for measuring small animal retinal structure and retinal blood flow. This non-invasive imaging technology is a promising tool for monitoring disease progression in rat and mouse models to assess ocular disease pathogenesis and response to treatment.

  13. Spectral modulation interferometry for quantitative phase imaging

    PubMed Central

    Shang, Ruibo; Chen, Shichao; Li, Chengshuai; Zhu, Yizheng

    2015-01-01

    We propose a spectral-domain interferometric technique, termed spectral modulation interferometry (SMI), and present its application to high-sensitivity, high-speed, and speckle-free quantitative phase imaging. In SMI, one-dimensional complex field of an object is interferometrically modulated onto a broadband spectrum. Full-field phase and intensity images are obtained by scanning along the orthogonal direction. SMI integrates the high sensitivity of spectral-domain interferometry with the high speed of spectral modulation to quantify fast phase dynamics, and its dispersive and confocal nature eliminates laser speckles. The principle and implementation of SMI are discussed. Its performance is evaluated using static and dynamic objects. PMID:25780737

  14. Synchronous Phase-Resolving Flash Range Imaging

    NASA Technical Reports Server (NTRS)

    Pain, Bedabrata; Hancock, Bruce

    2007-01-01

    An apparatus, now undergoing development, for range imaging based on measurement of the round-trip phase delay of a pulsed laser beam is described. The apparatus would operate in a staring mode. A pulsed laser would illuminate a target. Laser light reflected from the target would be imaged on a verylarge- scale integrated (VLSI)-circuit image detector, each pixel of which would contain a photodetector and a phase-measuring circuit. The round-trip travel time for the reflected laser light incident on each pixel, and thus the distance to the portion of the target imaged in that pixel, would be measured in terms of the phase difference between (1) the photodetector output pulse and (2) a local-oscillator signal that would have a frequency between 10 and 20 MHz and that would be synchronized with the laser-pulse-triggering signal.

  15. Single image orthogonal fringe technique for resolution enhancement of the Fourier transform fringe analysis method

    NASA Astrophysics Data System (ADS)

    Tavares, Paulo J.; Vaz, Mário A. P.

    2013-03-01

    Gradient range and spatial resolution in Fourier Transform Profilometry depend on the size of the filter window in reciprocal space. The proposed methods to date for the elimination of the fundamental frequency and enlargement of the filter window are either too computationally complex or depend on the possibility of using two frames, thus disabling the method's ability to cope with dynamic situations and subjecting the results to possible intensity changes between the two frame acquisitions. This article describes a simple method for using a single crossed fringe pattern to accomplish that objective, greatly improving the previously reported technique, whilst retaining its main advantages.

  16. Concentration profiles of collagen and proteoglycan in articular cartilage by Fourier transform infrared imaging and principal component regression

    NASA Astrophysics Data System (ADS)

    Yin, Jianhua; Xia, Yang; Lu, Mei

    2012-03-01

    Fourier-transform infrared imaging (FT-IRI) technique with the principal component regression (PCR) method was used to quantitatively determine the 2D images and the depth-dependent concentration profiles of two principal macromolecular components (collagen and proteoglycan) in articular cartilage. Ten 6 μm thick sections of canine humeral cartilage were imaged at a pixel size of 6.25 μm in FT-IRI. The infrared spectra extracted from FT-IRI experiments were imported into a PCR program to calculate the quantitative distributions of both collagen and proteoglycan in dry cartilage, which were subsequently converted into the wet-weight based concentration profiles. The proteoglycan profiles by FT-IRI and PCR significantly correlated in linear regression with the proteoglycan profiles by the non-destructive μMRI (the goodness-of-fit 0.96 and the Pearson coefficient 0.98). Based on these concentration relationships, the concentration images of collagen and proteoglycan in both healthy and lesioned articular cartilage were successfully constructed two dimensionally. The simultaneous construction of both collagen and proteoglycan concentration images demonstrates that this combined imaging and chemometrics approach could be used as a sensitive tool to accurately resolve and visualize the concentration distributions of macromolecules in biological tissues.

  17. Quantitative x-ray phase imaging at the nanoscale by multilayer Laue lenses.

    PubMed

    Yan, Hanfei; Chu, Yong S; Maser, Jörg; Nazaretski, Evgeny; Kim, Jungdae; Kang, Hyon Chol; Lombardo, Jeffrey J; Chiu, Wilson K S

    2013-01-01

    For scanning x-ray microscopy, many attempts have been made to image the phase contrast based on a concept of the beam being deflected by a specimen, the so-called differential phase contrast imaging (DPC). Despite the successful demonstration in a number of representative cases at moderate spatial resolutions, these methods suffer from various limitations that preclude applications of DPC for ultra-high spatial resolution imaging, where the emerging wave field from the focusing optic tends to be significantly more complicated. In this work, we propose a highly robust and generic approach based on a Fourier-shift fitting process and demonstrate quantitative phase imaging of a solid oxide fuel cell (SOFC) anode by multilayer Laue lenses (MLLs). The high sensitivity of the phase to structural and compositional variations makes our technique extremely powerful in correlating the electrode performance with its buried nanoscale interfacial structures that may be invisible to the absorption and fluorescence contrasts. PMID:23419650

  18. Quantitative x-ray phase imaging at the nanoscale by multilayer Laue lenses

    PubMed Central

    Yan, Hanfei; Chu, Yong S.; Maser, Jörg; Nazaretski, Evgeny; Kim, Jungdae; Kang, Hyon Chol; Lombardo, Jeffrey J.; Chiu, Wilson K. S.

    2013-01-01

    For scanning x-ray microscopy, many attempts have been made to image the phase contrast based on a concept of the beam being deflected by a specimen, the so-called differential phase contrast imaging (DPC). Despite the successful demonstration in a number of representative cases at moderate spatial resolutions, these methods suffer from various limitations that preclude applications of DPC for ultra-high spatial resolution imaging, where the emerging wave field from the focusing optic tends to be significantly more complicated. In this work, we propose a highly robust and generic approach based on a Fourier-shift fitting process and demonstrate quantitative phase imaging of a solid oxide fuel cell (SOFC) anode by multilayer Laue lenses (MLLs). The high sensitivity of the phase to structural and compositional variations makes our technique extremely powerful in correlating the electrode performance with its buried nanoscale interfacial structures that may be invisible to the absorption and fluorescence contrasts. PMID:23419650

  19. TH-E-17A-08: Estimation of Image Quality of 4-Dimensional Computed Tomography (4DCT) Via Fourier Analysis of Corresponding 1D Breathing Surrogate

    SciTech Connect

    Caraveo, M; McNamara, J; Rimner, A; Yorke, E; Li, G; Wei, J

    2014-06-15

    Purpose: Motion artifacts are common in patient 4DCT, leading to an illdefined tumor volume with variation up to 110% or setting up a poor foundation with low imaging fidelity for tumor motion study. We developed a method to estimate 4DCT image quality by establishing a correlation between the severity of motion artifacts in 4DCT images and the periodicity of corresponding 1D respiratory wave-function (1DRW) surrogate used for 4DCT reconstruction. Methods: Fast Fourier Transformation (FFT) was applied to analyze 1DRW periodicity, defined as the sum of the 5 largest Fourier coefficients, ranging in 0–1. Distortional motion artifacts of cine-scan 4DCT at the junctions of adjacent couchposition scans around the diaphragm were identified in 3 categories: incomplete, overlapping and duplicate. To quantify these artifacts, the discontinuity of the diaphragm at the junctions was measured in distance and averaged along 6 directions in 3 orthogonal views. Mean and sum artifacts per junction (APJ) across the entire diaphragm were calculated in each breathing phase. To make the APJ inter-patient comparable, patientspecific motion was removed from APJ by dividing patient-specific diaphragmatic velocity (displacement divided by the mean period, from FFT analysis of the 1DRW) and the normalized APJ was defined as motion artifact severity (MAS). Twenty-five patients with free-breathing 10-phase 4DCT and corresponding 1DRW surrogate datasets were studied. Results: A mild correlation of 0.56 was found between 1DRW periodicity and 4DCT artifact severity. Higher MAS tends to appear around mid inhalation and mid exhalation and the lowest MAS tends to be around full exhalation. The breathing periodicity of >0.8 possesses minimal motion artifacts. Conclusion: The 1D-4D correlation provides a fast means to estimate 4DCT image quality. Using 1DRW signal, we can retrospectively screen out high-quality 4DCT images for clinical research (periodicity>0.8) and prospectively identify poor breathers as candidates of breath coaching prior to 4DCT scan. This research is in part supported by NIH (U54CA137788/132378). MC would like to thank MSKCC summer medical student research program supported by National Cancer Institute and hosted by Department of Medical Physics at MSKCC.

  20. Imaging IR spectrometer, phase 2

    NASA Technical Reports Server (NTRS)

    Gradie, Jonathan; Lewis, Ralph; Lundeen, Thomas; Wang, Shu-I

    1990-01-01

    The development is examined of a prototype multi-channel infrared imaging spectrometer. The design, construction and preliminary performance is described. This instrument is intended for use with JPL Table Mountain telescope as well as the 88 inch UH telescope on Mauna Kea. The instrument is capable of sampling simultaneously the spectral region of 0.9 to 2.6 um at an average spectral resolution of 1 percent using a cooled (77 K) optical bench, a concave holographic grating and a special order sorting filter to allow the acquisition of the full spectral range on a 128 x 128 HgCdTe infrared detector array. The field of view of the spectrometer is 0.5 arcsec/pixel in mapping mode and designed to be 5 arcsec/pixel in spot mode. The innovative optical design has resulted in a small, transportable spectrometer, capable of remote operation. Commercial applications of this spectrometer design include remote sensing from both space and aircraft platforms as well as groundbased astronomical observations.

  1. Writing trace identification using ultraviolet Fourier-transform imaging spectroscopy technique

    NASA Astrophysics Data System (ADS)

    Lyu, Hang; Liao, Ningfang; Wu, Wenmin; Li, Yasheng; Cao, Bin

    2015-08-01

    Conventional identification methods of writing traces commonly utilize imaging or spectroscopic techniques which work in visible to near infrared range or short-wave infrared range. Yet they cannot be applied in identifying the erased writing traces. In this study, we perform a research in identification of erased writing traces applying an ultraviolet Fouriertransform imaging spectrometer. Experiments of classifying the reflected ultraviolet spectra of erasable pens are made. The resulting hyperspectral images demonstrate that the erased writing traces on printing paper can be clearly identified by this ultraviolet imaging spectrometer.

  2. Blocked element compensation in phased array imaging.

    PubMed

    Li, P C; Flax, S W; Ebbini, E S; O'Donnell, M

    1993-01-01

    In clinical applications using large apertures, a significant number of phased array elements may be blocked due to discontinuous acoustic windows into the body. These blocked elements produce undesired beamforming artifacts, degrading spatial and contrast resolution. To minimize these artifacts, an algorithm using multiple receive beams and the total-least-squares method is proposed. Simulations and experimental results show that this algorithm can effectively reduce imperfections in the point spread function of the imager. Combined with first-and second-order scatterer statistics derived from multiple receive beams, the algorithm is modified for blocked element compensation on distributed scattering sources. Results also indicate that compensated images are comparable to full array images, and that even full array images can be improved by removing undesired sidelobe contributions. This method, therefore, can enhance detection of low contrast lesions using large phased-array apertures. PMID:18263183

  3. Phase Imaging using Focusing Polycapillary Optics

    NASA Astrophysics Data System (ADS)

    Bashir, Sajid

    The interaction of X rays in diagnostic energy range with soft tissues can be described by Compton scattering and by the complex refractive index, which together characterize the attenuation properties of the tissue and the phase imparted to X rays passing through it. Many soft tissues exhibit extremely similar attenuation, so that their discrimination using conventional radiography, which generates contrast in an image through differential attenuation, is challenging. However, these tissues will impart phase differences significantly greater than attenuation differences to the X rays passing through them, so that phase-contrast imaging techniques can enable their discrimination. A major limitation to the widespread adoption of phase-contrast techniques is that phase contrast requires significant spatial coherence of the X-ray beam, which in turn requires specialized sources. For tabletop sources, this often requires a small (usually in the range of 10-50 micron) X-ray source. In this work, polycapillary optics were employed to create a small secondary source from a large spot rotating anode. Polycapillary optics consist of arrays of small hollow glass tubes through which X rays can be guided by total internal reflection from the tube walls. By tapering the tubes to guide the X rays to a point, they can be focused to a small spot which can be used as a secondary source. The polycapillary optic was first aligned with the X-ray source. The spot size was measured using a computed radiography image plate. Images were taken at a variety of optic-to-object and object-to-detector distances and phase-contrast edge enhancement was observed. Conventional absorption images were also acquired at a small object-to detector distances for comparison. Background division was performed to remove strong non-uniformity due to the optics. Differential phase contrast reconstruction demonstrates promising preliminary results. This manuscript is divided into six chapters. The second chapter describes the limitations of conventional imaging methods and benefits of the phase imaging. Chapter three covers different types of X-ray photon interactions with matter. Chapter four describes the experimental set-up and different types of images acquired along with their analysis. Chapter five summarizes the findings in this project and describes future work as well.

  4. Fast Hypercomplex Polar Fourier Analysis

    NASA Astrophysics Data System (ADS)

    Yang, Zhuo; Kamata, Sei-Ichiro

    Hypercomplex polar Fourier analysis treats a signal as a vector field and generalizes the conventional polar Fourier analysis. It can handle signals represented by hypercomplex numbers such as color images. Hypercomplex polar Fourier analysis is reversible that means it can reconstruct image. Its coefficient has rotation invariance property that can be used for feature extraction. However in order to increase the computation speed, fast algorithm is needed especially for image processing applications like realtime systems and limited resource platforms. This paper presents fast hypercomplex polar Fourier analysis based on symmetric properties and mathematical properties of trigonometric functions. Proposed fast hypercomplex polar Fourier analysis computes symmetric points simultaneously, which significantly reduce the computation time.

  5. [Research of dual-photoelastic-modulator-based beat frequency modulation and Fourier-Bessel transform imaging spectrometer].

    PubMed

    Wang, Zhi-Bin; Zhang, Rui; Wang, Yao-Li; Huang, Yan-Fei; Chen, You-Hua; Wang, Li-Fu; Yang, Qiang

    2014-02-01

    As the existing photoelastic-modulator(PEM) modulating frequency in the tens of kHz to hundreds of kHz between, leading to frequency of modulated interference signal is higher, so ordinary array detector cannot effectively caprure interference signal..A new beat frequency modulation method based on dual-photoelastic-modulator (Dual-PEM) and Fourier-Bessel transform is proposed as an key component of dual-photoelastic-modulator-based imaging spectrometer (Dual-PEM-IS) combined with charge coupled device (CCD). The dual-PEM are operated as an electro-optic circular retardance modulator, Operating the PEMs at slightly different resonant frequencies w1 and w2 respectively, generates a differential signal at a much lower heterodyne frequency that modulates the incident light. This method not only retains the advantages of the existing PEM, but also the frequency of modulated photocurrent decreased by 2-3 orders of magnitude (10-500 Hz) and can be detected by common array detector, and the incident light spectra can be obtained by Fourier-Bessel transform of low frequency component in the modulated signal. The method makes the PEM has the dual capability of imaging and spectral measurement. The basic principle is introduced, the basic equations is derived, and the feasibility is verified through the corresponding numerical simulation and experiment. This method has' potential applications in imaging spectrometer technology, and analysis of the effect of deviation of the optical path difference. This work provides the necessary theoretical basis for remote sensing of new Dual-PEM-IS and for engineering implementation of spectra inversion. PMID:24822442

  6. Digital signal processing for step-scan phase and electrochemical potential double-modulation Fourier transform infrared spectrometry.

    PubMed

    Brevnov, Dmitri A; Hutter, Eliza; Fendler, Janos H

    2004-02-01

    Step-scan double-modulation (phase and electrochemical potential) Fourier transform infrared (FT-IR) spectrometry provides both spectroscopic and dynamic information about faradaic reactions. Recently introduced digital signal processing (DSP) can be used, instead of two lock-in amplifiers, for the optical signal demodulation at two modulation frequencies. In order to establish the merits of double-modulation FT-IR spectrometry with DSP, spectro-electrochemical experiments are performed in the attenuated total reflection configuration and with the commonly used ferri/ferrocyanide redox couple. Because of a large potential drop associated with the uncompensated resistance, a satisfactory signal-to-noise ratio for the alternating current (ac) optical measurements is obtained only with the employment of positive feedback compensation. In this arrangement, the amplitude of electrochemical modulation is sufficiently large to convert a significant fraction of the reduced form to the oxidized form and back to the reduced form. Large amplitude ac voltammetry demonstrates that the phase of faradaic admittance at the formal potential is approximately 45 degrees at 2.00 Hz. In addition, these experiments allow for calculation of the interfacial ac potential. This variable is needed for the normalization of the in-phase and the quadrature spectra in order to overcome the problem associated with the iR(u) drop. Because of the integral relationship between the faradaic current and the electromodulation reflectance coefficient, the phases of electromodulation reflectance coefficient with respect to the interfacial ac potential are expected to be -45 degrees and 135 degrees for the reduced and oxidized forms, respectively. However, dynamic information from double-modulation FT-IR spectrometry is available only if demodulation at the electrochemical potential modulation frequency is performed with respect to a defined phase. Because of an undefined demodulation phase implemented in the current version of DSP software, step-scan double-modulation FT-IR spectrometry with DSP is suitable only to provide spectroscopic information. In order to overcome this limitation, the demodulation of the ac optical signal at the electrochemical modulation frequency must be synchronized in phase with the ac potential modulation applied to the electrochemical cell. PMID:17140478

  7. Phase diversity for three-dimensional imaging.

    PubMed

    Kner, Peter

    2013-10-01

    Phase diversity (PD) is a powerful technique for estimating wavefront aberrations from two-dimensional images of extended scenes. PD can work with extended incoherent images and, in an adaptive optics system, does not need extra hardware in addition to the deformable mirror. For these reasons, PD should be well suited to aberration measurement in microscopy applications. But, in biological widefield microscopy, the objects being imaged are frequently three-dimensional, and the images contain out-of-focus light. In this paper, we introduce multiplane PD and show that PD can be extended to widefield imaging of three-dimensional objects. This should be particularly useful in the field of biological fluorescence microscopy where the objects are very light sensitive and the aberrations cannot easily be determined. PMID:24322853

  8. Final design of SITELLE: a wide-field imaging Fourier transform spectrometer for the Canada-France-Hawaii Telescope

    NASA Astrophysics Data System (ADS)

    Grandmont, F.; Drissen, L.; Mandar, Julie; Thibault, S.; Baril, Marc

    2012-09-01

    We report here on the current status of SITELLE, an imaging Fourier transform spectrometer to be installed on the Canada-France Hawaii Telescope in 2013. SITELLE is an Integral Field Unit (IFU) spectrograph capable of obtaining the visible (350 nm - 900 nm) spectrum of every pixel of a 2k x 2k CCD imaging a field of view of 11 x 11 arcminutes, with 100% spatial coverage and a spectral resolution ranging from R = 1 (deep panchromatic image) to R < 104 (for gas dynamics). SITELLE will cover a field of view 100 to 1000 times larger than traditional IFUs, such as GMOS-IFU on Gemini or the upcoming MUSE on the VLT. SITELLE follows on the legacy of BEAR, an imaging conversion of the CFHT FTS and the direct successor of SpIOMM, a similar instrument attached to the 1.6-m telescope of the Observatoire du Mont-Mégantic in Québec. SITELLE will be used to study the structure and kinematics of HII regions and ejecta around evolved stars in the Milky Way, emission-line stars in clusters, abundances in nearby gas-rich galaxies, and the star formation rate in distant galaxies.

  9. Quantitative Fourier Domain Optical Coherence Tomography Imaging of the Ocular Anterior Segment

    NASA Astrophysics Data System (ADS)

    McNabb, Ryan Palmer

    Clinical imaging within ophthalmology has had transformative effects on ocular health over the last century. Imaging has guided clinicians in their pharmaceutical and surgical treatments of macular degeneration, glaucoma, cataracts and numerous other pathologies. Many of the imaging techniques currently used are photography based and are limited to imaging the surface of ocular structures. This limitation forces clinicians to make assumptions about the underlying tissue which may reduce the efficacy of their diagnoses. Optical coherence tomography (OCT) is a non-invasive, non-ionizing imaging modality that has been widely adopted within the field of ophthalmology in the last 15 years. As an optical imaging technique, OCT utilizes low-coherence interferometry to produce micron-scale three-dimensional datasets of a tissue's structure. Much of the human body consists of tissues that significantly scatter and attenuate optical signals limiting the imaging depth of OCT in those tissues to only 1-2mm. However, the ocular anterior segment is unique among human tissue in that it is primarily transparent or translucent. This allows for relatively deep imaging of tissue structure with OCT and is no longer limited by the optical scattering properties of the tissue. This goal of this work is to develop methods utilizing OCT that offer the potential to reduce the assumptions made by clinicians in their evaluations of their patients' ocular anterior segments. We achieved this by first developing a method to reduce the effects of patient motion during OCT volume acquisitions allowing for accurate, three dimensional measurements of corneal shape. Having accurate corneal shape measurements then allowed us to determine corneal spherical and astigmatic refractive contribution in a given individual. This was then validated in a clinical study that showed OCT better measured refractive change due to surgery than other clinical devices. Additionally, a method was developed to combine the clinical evaluation of the iridocorneal angle through gonioscopy with OCT.

  10. Phase correction algorithms for a snapshot hyperspectral imaging system

    NASA Astrophysics Data System (ADS)

    Chan, Victoria C.; Kudenov, Michael; Dereniak, Eustace

    2015-09-01

    We present image processing algorithms that improve spatial and spectral resolution on the Snapshot Hyperspectral Imaging Fourier Transform (SHIFT) spectrometer. Final measurements are stored in the form of threedimensional datacubes containing the scene's spatial and spectral information. We discuss calibration procedures, review post-processing methods, and present preliminary results from proof-of-concept experiments.

  11. Phase-Scrambler Plate Spreads Point Image

    NASA Technical Reports Server (NTRS)

    Edwards, Oliver J.; Arild, Tor

    1992-01-01

    Array of small prisms retrofit to imaging lens. Phase-scrambler plate essentially planar array of small prisms partitioning aperture of lens into many subapertures, and prism at each subaperture designed to divert relatively large diffraction spot formed by that subaperture to different, specific point on focal plane.

  12. Phased Contrast X-Ray Imaging

    ScienceCinema

    Erin Miller

    2012-12-31

    The Pacific Northwest National Laboratory is developing a range of technologies to broaden the field of explosives detection. Phased contrast X-ray imaging, which uses silicon gratings to detect distortions in the X-ray wave front, may be applicable to mail or luggage scanning for explosives; it can also be used in detecting other contraband, small-parts inspection, or materials characterization.

  13. Digitizing Images for Curriculum 21: Phase II.

    ERIC Educational Resources Information Center

    Walker, Alice D.

    Although visual databases exist for the study of art, architecture, geography, health care, and other areas, readily accessible sources of quality images are not available for engineering faculty interested in developing multimedia modules or for student projects. Presented here is a brief review of Phase I of the Engineering Visual Database…

  14. Analysis of hyper-spectral data derived from an imaging Fourier transform: A statistical perspective

    SciTech Connect

    Sengupta, S.K.; Clark, G.A.; Fields, D.J.

    1996-01-10

    Fourier transform spectrometers (FTS) using optical sensors are increasingly being used in various branches of science. Typically, a FTS generates a three-dimensional data cube with two spatial dimensions and one frequency/wavelength dimension. The number of frequency dimensions in such data cubes is generally very large, often in the hundreds, making data analytical procedures extremely complex. In the present report, the problem is viewed from a statistical perspective. A set of procedures based on the high degree of inter-channel correlation structure often present in such hyper-spectral data, has been identified and applied to an example data set of dimension 100 x 128 x 128 comprising 128 spectral bands. It is shown that in this case, the special eigen-structure of the correlation matrix has allowed the authors to extract just a few linear combinations of the channels (the significant principal vectors) that effectively contain almost all of the spectral information contained in the data set analyzed. This in turn, enables them to segment the objects in the given spatial frame using, in a parsimonious yet highly effective way, most of the information contained in the data set.

  15. Quadriwave lateral shearing interferometry for quantitative phase microscopy: coupling phase imaging and fluorescence imaging

    NASA Astrophysics Data System (ADS)

    Bon, Pierre; Savatier, Julien; Wattellier, Benoit; Marguet, Didier; Monneret, Serge

    2011-03-01

    Phase imaging with a high-resolution wavefront sensor is a useful setup for biological imaging. Our setup is based on a quadriwave lateral shearing interferometer mounted on a commercial non-modified transmission white-light microscope. That allows us to make simultaneous measurement in both quantitative transmission phase and fluorescence imaging. We propose here to study co-localization between phase and fluorescence on african green monkey kidney COS7 cells. Phase permits an enhanced visualization of the whole cell and intracellular components while the fluorescence allows a complete identification of each component. Post treatments on phase-shift images are proposed and become very interesting for enhanced visualization of small details such as vesicles or mitochondrias.

  16. Demonstration of Imaging Fourier Transform Spectrometer (FTS) Performance for Planetary and Geostationary Earth Observing

    NASA Technical Reports Server (NTRS)

    Revercomb, Henry E.; Sromovsky, Lawrence A.; Fry, Patrick M.; Best, Fred A.; LaPorte, Daniel D.

    2001-01-01

    The combination of massively parallel spatial sampling and accurate spectral radiometry offered by imaging FTS makes it extremely attractive for earth and planetary remote sensing. We constructed a breadboard instrument to help assess the potential for planetary applications of small imaging FTS instruments in the 1 - 5 micrometer range. The results also support definition of the NASA Geostationary Imaging FTS (GIFTS) instrument that will make key meteorological and climate observations from geostationary earth orbit. The Planetary Imaging FTS (PIFTS) breadboard is based on a custom miniaturized Bomen interferometer that uses corner cube reflectors, a wishbone pivoting voice-coil delay scan mechanism, and a laser diode metrology system. The interferometer optical output is measured by a commercial infrared camera procured from Santa Barbara Focalplane. It uses an InSb 128x128 detector array that covers the entire FOV of the instrument when coupled with a 25 mm focal length commercial camera lens. With appropriate lenses and cold filters the instrument can be used from the visible to 5 micrometers. The delay scan is continuous, but slow, covering the maximum range of +/- 0.4 cm in 37.56 sec at a rate of 500 image frames per second. Image exposures are timed to be centered around predicted zero crossings. The design allows for prediction algorithms that account for the most recent fringe rate so that timing jitter produced by scan speed variations can be minimized. Response to a fixed source is linear with exposure time nearly to the point of saturation. Linearity with respect to input variations was demonstrated to within 0.16% using a 3-point blackbody calibration. Imaging of external complex scenes was carried out at low and high spectral resolution. These require full complex calibration to remove background contributions that vary dramatically over the instrument FOV. Testing is continuing to demonstrate the precise radiometric accuracy and noise characteristics.

  17. Computer-generated phase-modulated full parallax holographic stereograms without conjugate images

    NASA Astrophysics Data System (ADS)

    Pei, Chuang; Yan, Xingpeng; Jiang, Xiaoyu

    2014-10-01

    A pure phase-modulated computer-generated hologram (CGH) method is presented to generate a full parallax holographic stereogram. The holographic stereogram plane is divided into several two-dimensional holographic elements (hogels). The spectra of the hogels are rendered from multiview full parallax images of three-dimensional (3-D) objects. The phase-modulated hogel is calculated by iterative Fourier transform algorithms to improve diffraction efficiency and eliminate conjugate images. A gray calibration technique is introduced to generate the accurate intensity modulation of pure phase hogels. The holographic stereogram that we proposed is reconstructed by an optical system based on a phase only spatial light modulator. The experimental results demonstrate that our proposed method can successfully reconstruct parallax images of 3-D objects.

  18. Quantitative phase imaging with partially coherent illumination.

    PubMed

    Nguyen, T H; Edwards, C; Goddard, L L; Popescu, G

    2014-10-01

    In this Letter, we formulate a mathematical model for predicting experimental outcomes in quantitative phase imaging (QPI) when the illumination field is partially spatially coherent. We derive formulae that apply to QPI and discuss expected results for two classes of QPI experiments: common path and traditional interferometry, under varying degrees of spatial coherence. In particular, our results describe the physical relationship between the spatial coherence of the illuminating field and the halo effect, which is well known in phase-contrast microscopy. We performed experiments relevant to this common situation and found that our theory is in excellent agreement with the data. With this new understanding of the effects of spatial coherence, our formulae offer an avenue for removing halo artifacts from phase images. PMID:25360915

  19. Discrimination of healthy and osteoarthritic articular cartilages by Fourier transform infrared imaging and partial least squares-discriminant analysis

    NASA Astrophysics Data System (ADS)

    Zhang, Xue-Xi; Yin, Jian-Hua; Mao, Zhi-Hua; Xia, Yang

    2015-06-01

    Fourier transform infrared imaging (FTIRI) combined with chemometrics algorithm has strong potential to obtain complex chemical information from biology tissues. FTIRI and partial least squares-discriminant analysis (PLS-DA) were used to differentiate healthy and osteoarthritic (OA) cartilages for the first time. A PLS model was built on the calibration matrix of spectra that was randomly selected from the FTIRI spectral datasets of healthy and lesioned cartilage. Leave-one-out cross-validation was performed in the PLS model, and the fitting coefficient between actual and predicted categorical values of the calibration matrix reached 0.95. In the calibration and prediction matrices, the successful identifying percentages of healthy and lesioned cartilage spectra were 100% and 90.24%, respectively. These results demonstrated that FTIRI combined with PLS-DA could provide a promising approach for the categorical identification of healthy and OA cartilage specimens.

  20. Proteoglycan concentrations in healthy and diseased articular cartilage by Fourier transform infrared imaging and principal component regression

    NASA Astrophysics Data System (ADS)

    Yin, Jianhua; Xia, Yang

    2014-12-01

    Fourier transform infrared imaging (FTIRI) combining with principal component regression (PCR) analysis were used to determine the reduction of proteoglycan (PG) in articular cartilage after the transection of the anterior cruciate ligament (ACL). A number of canine knee cartilage sections were harvested from the meniscus-covered and meniscus-uncovered medial tibial locations from the control joints, the ACL joints at three time points after the surgery, and their contralateral joints. The PG loss in the ACL cartilage was related positively to the durations after the surgery. The PG loss in the contralateral knees was less than that of the ACL knees. The PG loss in the meniscus-covered cartilage was less than that of the meniscus-uncovered tissue in both ACL and contralateral knees. The quantitative mapping of PG loss could monitor the disease progression and repair processes in arthritis.

  1. Subcellular Biochemical Investigation of Purkinje Neurons Using Synchrotron Radiation Fourier Transform Infrared Spectroscopic Imaging with a Focal Plane Array Detector

    PubMed Central

    2013-01-01

    Coupling Fourier transform infrared spectroscopy with focal plane array detectors at synchrotron radiation sources (SR-FTIR-FPA) has provided a rapid method to simultaneously image numerous biochemical markers in situ at diffraction limited resolution. Since cells and nuclei are well resolved at this spatial resolution, a direct comparison can be made between FTIR functional group images and the histology of the same section. To allow histological analysis of the same section analyzed with infrared imaging, unfixed air-dried tissue sections are typically fixed (after infrared spectroscopic analysis is completed) via immersion fixation. This post fixation process is essential to allow histological staining of the tissue section. Although immersion fixation is a common practice in this filed, the initial rehydration of the dehydrated unfixed tissue can result in distortion of subcellular morphology and confound correlation between infrared images and histology. In this study, vapor fixation, a common choice in other research fields where postfixation of unfixed tissue sections is required, was employed in place of immersion fixation post spectroscopic analysis. This method provided more accurate histology with reduced distortions as the dehydrated tissue section is fixed in vapor rather than during rehydration in an aqueous fixation medium. With this approach, accurate correlation between infrared images and histology of the same section revealed that Purkinje neurons in the cerebellum are rich in cytosolic proteins and not depleted as once thought. In addition, we provide the first direct evidence of intracellular lactate within Purkinje neurons. This highlights the significant potential for future applications of SR-FTIR-FPA imaging to investigate cellular lactate under conditions of altered metabolic demand such as increased brain activity and hypoxia or ischemia. PMID:23638613

  2. Compression and denoising in magnetic resonance imaging via SVD on the Fourier domain using computer algebra

    NASA Astrophysics Data System (ADS)

    Díaz, Felipe

    2015-09-01

    Magnetic resonance (MR) data reconstruction can be computationally a challenging task. The signal-to-noise ratio might also present complications, especially with high-resolution images. In this sense, data compression can be useful not only for reducing the complexity and memory requirements, but also to reduce noise, even to allow eliminate spurious components.This article proposes the use of a system based on singular value decomposition of low order for noise reconstruction and reduction in MR imaging system. The proposed method is evaluated using in vivo MRI data. Rebuilt images with less than 20 of the original data and with similar quality in terms of visual inspection are presented. Also a quantitative evaluation of the method is presented.

  3. Demonstration of imaging Fourier Transform Spectrometer (FTS) performance for planetary and geostationary Earth observing

    NASA Astrophysics Data System (ADS)

    Revercomb, Henry E.; Sromovsky, Lawrence A.; Fry, Patrick M.; Best, Fred A.; LaPorte, Daniel D.

    2001-02-01

    The combination of massively parallel spatial sampling and accurate spectral radiometry offered by imaging FTS makes it extremely attractive for earth and planetary remote sensing. We constructed a breadboard instrument to help assess the potential for planetary applications of small imaging FTS instruments in the 1-5 micrometers range. The results also support definition of the NASA Geostationary Imaging FTS instrument that will make key meteorological and climate observations from geostationary earth orbit. The PIFTS pivoting voice- coil delay scan mechanism, and laser diode metrology system. The interferometer optical output is measured by a commercial IR camera procured from Santa Barbara Focal plane. It uses an InSb 128 by 128 detector array that covers the entire FOV of the instrument when coupled with a 25-mm focal length commercial camera lens. With appropriate lenses and cold filters the instrument can be used from the visible to 5 micrometers . The delay scan is continuos, but slow, covering the maximum range of +/- 0.4 cm in 37.56 sec at a rate of 500 image frames per second. Image exposures are timed to be centered around predicted zero crossings. The design allows for prediction algorithms that account for the most recent fringe rate so that timing jitter produced by scan speed variations can be minimized. Response to a fixed source is linear with exposure time nearly to the point of saturation. Linearity with respect to input variations was demonstrated to within 0.16 percent using a 3-point blackbody calibration. Imaging of external complex scenes was carried out at low and high spectral resolution. These require full complex calibration to remove background contributions that vary dramatically over the instrument FOV. Testing is continuing to demonstrate the precise radiometric accuracy and noise characteristics.

  4. Ruthenium trisbipyridine as a candidate for gas-phase spectroscopic studies in a Fourier transform mass spectrometer

    DOE PAGESBeta

    Scott, Jill R.; Ham, Jason E.; Durham, Bill; Tremblay, Paul L.

    2004-01-01

    Metal polypyridines are excellent candidates for gas-phase optical experiments where their intrinsic properties can be studied without complications due to the presence of solvent. The fluorescence lifetimes of [Ru(bpy) 3 ] 1+ trapped in an optical detection cell within a Fourier transform mass spectrometer were obtained using matrix-assisted laser desorption/ionization to generate the ions with either 2,5-dihydroxybenzoic acid (DHB) or sinapinic acid (SA) as matrix. All transients acquired, whether using DHB or SA for ion generation, were best described as approximately exponential decays. The rate constant for transients derived using DHB as matrix was 4×10 7 s −1 ,more » while the rate constant using SA was 1×10 7 s −1 . Some suggestions of multiple exponential decay were evident although limited by the quality of the signals. Photodissociation experiments revealed that [Ru(bpy) 3 ] 1+ generated using DHB can decompose to [Ru(bpy) 2 ] 1+ , whereas ions generated using SA showed no decomposition. Comparison of the mass spectra with the fluorescence lifetimes illustrates the promise of incorporating optical detection with trapped ion mass spectrometry techniques.« less

  5. Ground-Based Measurement Experiment and First Results with Geosynchronous-Imaging Fourier Transform Spectrometer Engineering Demonstration Unit

    NASA Technical Reports Server (NTRS)

    Zhou, Daniel K.; Smith, William L.; Bingham, Gail E.; Huppi, Ronald J.; Revercomb, Henry E.; Zollinger, Lori J.; Larar, Allen M.; Liu, Xu; Tansock, Joseph J.; Reisse, Robert A.; Hooker, Ronald

    2007-01-01

    The geosynchronous-imaging Fourier transform spectrometer (GIFTS) engineering demonstration unit (EDU) is an imaging infrared spectrometer designed for atmospheric soundings. It measures the infrared spectrum in two spectral bands (14.6 to 8.8 microns, 6.0 to 4.4 microns) using two 128 x 128 detector arrays with a spectral resolution of 0.57 cm(exp -1) with a scan duration of approximately 11 seconds. From a geosynchronous orbit, the instrument will have the capability of taking successive measurements of such data to scan desired regions of the globe, from which atmospheric status, cloud parameters, wind field profiles, and other derived products can be retrieved. The GIFTS EDU provides a flexible and accurate testbed for the new challenges of the emerging hyperspectral era. The EDU ground-based measurement experiment, held in Logan, Utah during September 2006, demonstrated its extensive capabilities and potential for geosynchronous and other applications (e.g., Earth observing environmental measurements). This paper addresses the experiment objectives and overall performance of the sensor system with a focus on the GIFTS EDU imaging capability and proof of the GIFTS measurement concept.

  6. Design and first results of a Fourier Transform imaging spectrometer in the 3-5 μm range

    NASA Astrophysics Data System (ADS)

    Matallah, Noura; Sauer, Hervé; Goudail, François; Fontanella, Jean-Claude; Ferrec, Yann; Taboury, Jean; Chavel, Pierre

    2011-10-01

    An imaging spectrometer in the 3-5 μm wavelength range is presented. This wavelength range reveals important information about scenes such as gas or landmine detection, but the amount of light is usually low and signal to noise ratio is a real issue. We selected a Fourier transform (FT) configuration, expecting an advantage in signal to noise ratio in the presence of detector noise. Radiometric and noise models are summarized. A Michelson interferometer with its mirrors replaced by twin mirrors arranged at right angles in a hollow roof was chosen for its nearly straight equidistant fringes localized at infinity. Because in such FT-based spectral imagers, the interferogram is acquired over the whole field of the camera while the scene of interest scans the path difference range, vignetting should be strongly limited while keeping the size of the interferometer as small as possible for manufacturability and cost reasons. The key point for that purpose is to put the entrance pupil of the imaging lens inside the interferometer and to make careful trade-offs between lens F number and angular field of view. The resulting system has a spectral resolution of about 25cm-1 that fulfils the requirement for most targeted applications. Examples of absorption bands detection are shown.

  7. Discrimination of healthy and osteoarthritic articular cartilage by Fourier transform infrared imaging and Fisher’s discriminant analysis

    PubMed Central

    Mao, Zhi-Hua; Yin, Jian-Hua; Zhang, Xue-Xi; Wang, Xiao; Xia, Yang

    2016-01-01

    Fourier transform infrared spectroscopic imaging (FTIRI) technique can be used to obtain the quantitative information of content and spatial distribution of principal components in cartilage by combining with chemometrics methods. In this study, FTIRI combining with principal component analysis (PCA) and Fisher’s discriminant analysis (FDA) was applied to identify the healthy and osteoarthritic (OA) articular cartilage samples. Ten 10-μm thick sections of canine cartilages were imaged at 6.25μm/pixel in FTIRI. The infrared spectra extracted from the FTIR images were imported into SPSS software for PCA and FDA. Based on the PCA result of 2 principal components, the healthy and OA cartilage samples were effectively discriminated by the FDA with high accuracy of 94% for the initial samples (training set) and cross validation, as well as 86.67% for the prediction group. The study showed that cartilage degeneration became gradually weak with the increase of the depth. FTIRI combined with chemometrics may become an effective method for distinguishing healthy and OA cartilages in future. PMID:26977354

  8. Tests of various colorants for application of a Fourier transform infrared imaging system to deciphering obliterated writings

    NASA Astrophysics Data System (ADS)

    Sugawara, Shigeru

    2015-10-01

    Obliterated writing is writing that has been obscured by different-colored materials. There are obliterated writings that cannot be detected by conventional methods. A method for deciphering such obliterated writings was developed in this study. Mid-infrared spectroscopic imaging in the wavelength range of 2.5-14 μm was used for deciphering because the infrared spectrum differs among different brands of colorants. Obliterated writings were made by pressing information protection stamps onto characters written by 4 kinds of colorants. The samples were tested for deciphering by the Fourier-transform infrared imaging system. Two peak areas of two specific wavenumber regions of each reflectance spectrum were calculated and the ratio of the two values is displayed as a unique gray scale in the spectroscopic image. As a result, the absorption peak at various wavenumbers could be used to decipher obliterated writings that could not be detected by the conventional methods. Ten different parameters for deciphering obliterated writing were found in this study.

  9. Concentration determination of collagen and proteoglycan in bovine nasal cartilage by Fourier transform infrared imaging and PLS

    NASA Astrophysics Data System (ADS)

    Zhang, Xuexi; Xiao, Zhi-Yan; Yin, Jianhua; Xia, Yang

    2014-09-01

    Fourier transform infrared imaging (FTIRI) combined with chemometrics can be used to detect the structure of bio-macromolecule, measure the concentrations of some components, and so on. In this study, FTIRI with Partial Least-Squares (PLS) regression was applied to study the concentration of two main components in bovine nasal cartilage (BNC), collagen and proteoglycan. An infrared spectrum library was built by mixing the collagen and chondroitin 6-sulfate (main of proteoglycan) at different ratios. Some pretreatments are needed for building PLS model. FTIR images were collected from BNC sections at 6.25μm and 25μm pixel size. The spectra extracted from BNC-FTIR images were imported into the PLS regression program to predict the concentrations of collagen and proteoglycan. These PLS-determined concentrations are agreed with the result in our previous work and biochemical analytical results. The prediction shows that the concentrations of collagen and proteoglycan in BNC are comparative on the whole. However, the concentration of proteoglycan is a litter higher than that of collagen, to some extent.

  10. Fourier Transform Infrared Spectroscopy for Identification and Quantification of Organic Functional Groups in Aqueous Phase Secondary Organic Aerosol

    NASA Astrophysics Data System (ADS)

    George, K.; Ruthenburg, T. C.; Smith, J.; Anastasio, C.; Dillner, A. M.

    2011-12-01

    Particles in the atmosphere influence visibility, climate, and human health. Secondary organic aerosols (SOA) formed from chemical reactions in the atmosphere constitute a portion of total organic particle mass. Most research on SOA has focused on gas phase reactions; however, reactions taking place in cloud and fog drops may be significant. One group of water-soluble compounds that participate in these reactions is phenols. Phenols, emitted from biomass burning, react in the aqueous phase to form low-volatility SOA products. The products formed from these reactions are currently poorly characterized. In order to characterize laboratory-generated samples, we are developing an attenuated total reflectance-Fourier transform infrared spectroscopic (ATR-FTIR) technique to identify and quantify organic functional groups in SOA. Aqueous SOA is made in the laboratory by illuminating solutions of phenolic compounds with an oxidant. The illuminated solution is then blown to dryness in order to determine the mass of SOA produced. The dry SOA is reconstituted in water and drops of this solution are placed onto a single-reflection ATR accessory. In order to identify and quantify functional groups in the complex SOA samples, it is necessary to calibrate with compounds and mixtures of compounds containing bond types similar to those found in the laboratory-generated SOA. Initially, focus has been placed on multiple peaks located in the region between 1800 cm-1 and 800 cm-1, including peaks for C=O and C-O. We distinguish between characteristic absorbances to begin determining the organic functional group composition of the SOA samples. This ATR-FTIR technique complements information from mass spectrometry measurements and allows us to quantify organic mass for non-volatile SOA products.

  11. The pericardial effusion pattern on phase images

    SciTech Connect

    Pavel, C.M.; Kahn, J.; Rich, S.; Gonzalez, P.; Turner, S.; Pavel, D.G.

    1984-02-01

    The effect of pericardial effusion on phase images of gated studies was investigated. Twenty-six patients with suspected or known pericardial effusion were correlated with echocardiography and/or clinical and other laboratory data to ascertain the presence and size of effusion. The phase image pattern and parameters were compared to the results previously obtained in seven normal patients, and in 26 patients with documented regional wall motion abnormalities but no evidence of pericardial effusion. The phase pattern was graded into five categories: typical (IV) (wide histogram, well defined concentric convex pattern, progressive delay toward the inferolateral area, identifiable also over the right ventricle); less pronounced (III); atypical (II); ill defined changes (I); and normal (0). Results: Group L (large pericardial effusion): four of six had pattern (IV) and the left ventricular histogram showed abnormal parameters. These patients had large free effusions in the pericardial sac and none had regional wall motion abnormalities. Two of six had pattern (III) and (II) but also had ancillary pericardial pathology and/or decreased ejection fraction. Group M (moderate pericardial effusion), S (small pericardial effusion), and A (absent pericardial effusion, but not normal) had variable phase images and numeric parameters. After therapeutic drainage of pericardial fluid two patients changed pattern from IV and III to 0 and a third from III to I. Category IV pattern is 100% specific for pericardial effusion; the combination of category IV or III is 87.5% specific and 61% sensitive for large and moderate pericardial effusion.

  12. Megahertz OCT for ultrawide-field retinal imaging with a 1050 nm Fourier domain mode-locked laser.

    PubMed

    Klein, Thomas; Wieser, Wolfgang; Eigenwillig, Christoph M; Biedermann, Benjamin R; Huber, Robert

    2011-02-14

    We demonstrate ultrahigh speed swept source retinal OCT imaging using a Fourier domain mode locked (FDML) laser. The laser uses a combination of a semiconductor optical amplifier and an ytterbium doped fiber amplifier to provide more than 50 mW output power. The 1050 nm FDML laser uses standard telecom fiber for the km long delay line instead of two orders of magnitude more expensive real single mode fiber. We investigate the influence of this "oligo-mode" fiber on the FDML laser performance. Two design configurations with 684,400 and 1,368,700 axial scans per second are investigated, 25x and 50x faster than current commercial instruments and more than 4x faster than previous single spot ophthalmic results. These high speeds enable the acquisition of densely sampled ultrawide-field data sets of the retina within a few seconds. Ultrawide-field data consisting of 1900 x 1900 A-scans with ~70° angle of view are acquired within only 3 and 6 seconds using the different setups. Such OCT data sets, more than double as large as previously reported, are collapsed to a 4 megapixel high definition fundus image. We achieve good penetration into the choroid by hardware spectral shaping of the laser output. The axial resolution in tissue is 12 µm (684 kHz) and 19 µm (1.37 MHz). A series of new data processing and imaging extraction protocols, enabled by the ultrawide-field isotropic data sets, are presented. Dense isotropic sampling enables both, cross-sectional images along arbitrary coordinates and depth-resolved en-face fundus images. Additionally, we investigate how isotropic averaging compares to the averaging of cross-sections along the slow axis. PMID:21369128

  13. Improved Two-Dimensional Millimeter-Wave Imaging for Concealed Weapon Detection Through Partial Fourier Sampling

    NASA Astrophysics Data System (ADS)

    Farsaei, Amir Ashkan; Mokhtari-Koushyar, Farzad; Javad Seyed-Talebi, Seyed Mohammad; Kavehvash, Zahra; Shabany, Mahdi

    2016-03-01

    Active millimeter-wave imaging based on synthetic aperture focusing offers certain unique and practical advantages in nondestructive testing applications. Traditionally, the imaging for this purpose is performed through a long procedure of raster scanning with a single antenna across a two-dimensional grid, leading to a slow, bulky, and expensive scanning platform. In this paper, an improved bistatic structure based on radial compressive sensing is proposed, where one fixed transmitter antenna and a linear array of receiving antennas are used. The main contributions of this paper are (a) reducing the scanning time, (b) improving the output quality, and (c) designing an inexpensive setup. These improvements are the result of the underlying proposed simpler scanning structure and faster reconstruction process.

  14. Improved Two-Dimensional Millimeter-Wave Imaging for Concealed Weapon Detection Through Partial Fourier Sampling

    NASA Astrophysics Data System (ADS)

    Farsaei, Amir Ashkan; Mokhtari-Koushyar, Farzad; Javad Seyed-Talebi, Seyed Mohammad; Kavehvash, Zahra; Shabany, Mahdi

    2015-11-01

    Active millimeter-wave imaging based on synthetic aperture focusing offers certain unique and practical advantages in nondestructive testing applications. Traditionally, the imaging for this purpose is performed through a long procedure of raster scanning with a single antenna across a two-dimensional grid, leading to a slow, bulky, and expensive scanning platform. In this paper, an improved bistatic structure based on radial compressive sensing is proposed, where one fixed transmitter antenna and a linear array of receiving antennas are used. The main contributions of this paper are (a) reducing the scanning time, (b) improving the output quality, and (c) designing an inexpensive setup. These improvements are the result of the underlying proposed simpler scanning structure and faster reconstruction process.

  15. Phase Superposition Processing for Ultrasonic Imaging

    NASA Astrophysics Data System (ADS)

    Tao, L.; Ma, X. R.; Tian, H.; Guo, Z. X.

    1996-06-01

    In order to improve the resolution of defect reconstruction for non-destructive evaluation, a new phase superposition processing (PSP) method has been developed on the basis of a synthetic aperture focusing technique (SAFT). The proposed method synthesizes the magnitudes of phase-superposed delayed signal groups. A satisfactory image can be obtained by a simple algorithm processing time domain radio frequency signals directly. In this paper, the theory of PSP is introduced and some simulation and experimental results illustrating the advantage of PSP are given.

  16. Extending Single-Molecule Microscopy Using Optical Fourier Processing

    PubMed Central

    2015-01-01

    This article surveys the recent application of optical Fourier processing to the long-established but still expanding field of single-molecule imaging and microscopy. A variety of single-molecule studies can benefit from the additional image information that can be obtained by modulating the Fourier, or pupil, plane of a widefield microscope. After briefly reviewing several current applications, we present a comprehensive and computationally efficient theoretical model for simulating single-molecule fluorescence as it propagates through an imaging system. Furthermore, we describe how phase/amplitude-modulating optics inserted in the imaging pathway may be modeled, especially at the Fourier plane. Finally, we discuss selected recent applications of Fourier processing methods to measure the orientation, depth, and rotational mobility of single fluorescent molecules. PMID:24745862

  17. Balloon Demonstrator Imaging Fourier Transform Spectrometer for the Measurement of Methane and Carbon Dioxide over the Arctic

    NASA Astrophysics Data System (ADS)

    McElroy, C. T.; Walker, K. A.; Vaziri, Z.; Moeini, O.; Martin, R.

    2014-12-01

    The Arctic multi-year ice cover is disappearing more rapidly than climate models estimate and the Arctic climate is also changing. With declining ice cover, the Arctic Ocean will likely be subject to increased shipping traffic in addition to exploration activity for natural resources with a concomitant increase in air pollution. Thus, there is a multifaceted need to monitor the polar region. A number of Canadian government departments, led by the Canadian Space Agency (CSA), are proposing the Polar Communications and Weather (PCW) mission to provide improved communications and critically important meteorological and air quality information for the Arctic using an operational meteorological imager. Two satellites in highly eccentric orbits with apogees at ~ 40,000 km over the Arctic would provide quasi-geostationary viewing over the Arctic with 24-7 coverage in the IR and measurements using solar reflected light in the summertime. The planned operational meteorological instrument is a 21-channel spectral imager with UV, visible, NIR and MIR channels similar to MODIS and ABI. This presentation will focus on the development of an Imaging Fourier Transform Spectrometer (IFTS) to be flown on a high-altitude balloon to demonstrate the capacity to monitor methane and carbon dioxide in the Arctic as part of the PHEOS-WCA (Weather, Climate and Air quality) mission, which is an atmospheric science complement to the operational PCW mission.Funding is now in place to develop the demonstrator IFTS to show that images of methane and carbon dioxide can be collected from space. The characteristics of the instrument and plans for the balloon flight will be discussed and details of the full PCW mission and PHEOS-WCA component will be presented. The author wishes to acknowledge the support of the PHEOS-WCA science team.

  18. Toward Fourier interferometry fluorescence excitation/emission imaging of malignant cells combined with photoacoustic microscopy

    NASA Astrophysics Data System (ADS)

    Kohen, Elli; Hirschberg, Joseph G.; Berry, John P.; Ozkutuk, Nuri; Ornek, Ceren; Monti, Marco; Leblanc, Roger M.; Schachtschabel, Dietrich O.; Haroon, Sumaira

    2003-10-01

    Dual excitation fluorescence imaging has been used as a first step towards multi-wavelength excitation/emission fluorescence spectral imaging. Target cells are transformed keratinocytes, and other osteosarcoma, human breast and color cancer cells. Mitochondrial membrane potential probes, e.g. TMRM (tetramethylrhodamine methyl ester), Mitotracker Green (Molecular Probes, Inc., Eugene OR,USA; a recently synthesized mitochondrial oxygen probe, [PRE,P1"- pyrene butyl)-2-rhodamine ester] allow dual excitation in the UV plus in teh blue-green spectral regions. Also, using the natural endogenous probe NAD(P)H, preliminary results indicate mitochondrial responses to metabolic challenges (e.g. glucose addition), plus changes in mitochonrial distribution and morphology. In terms of application to biomedicine (for diagnostiscs, prognostsics and drug trials) three parameters have been selected in addition to the natural probe NAD(P)H, i.e. vital fluorescence probing of mitochondria, lysosomes and Golgi apparatus. It is hoped that such a multiparameter approach will allow malignant cell characterization and grading. A new area being introduced is the use of similar methodology for biotechnical applications such as the study of the hydrogen-producing alga Chlamydomonas Reinhardtii, and possible agricultural applications, such as Saccharomyces yeast for oenology. Complementation by Photoacoustic Microscopy is also contemplated, to study the internal conversion component which follows the excitation by photons.

  19. A general theory of interference fringes in x-ray phase grating imaging

    SciTech Connect

    Yan, Aimin; Wu, Xizeng E-mail: liu@ou.edu; Liu, Hong E-mail: liu@ou.edu

    2015-06-15

    Purpose: The authors note that the concept of the Talbot self-image distance in x-ray phase grating interferometry is indeed not well defined for polychromatic x-rays, because both the grating phase shift and the fractional Talbot distances are all x-ray wavelength-dependent. For x-ray interferometry optimization, there is a need for a quantitative theory that is able to predict if a good intensity modulation is attainable at a given grating-to-detector distance. In this work, the authors set out to meet this need. Methods: In order to apply Fourier analysis directly to the intensity fringe patterns of two-dimensional and one-dimensional phase grating interferometers, the authors start their derivation from a general phase space theory of x-ray phase-contrast imaging. Unlike previous Fourier analyses, the authors evolved the Wigner distribution to obtain closed-form expressions of the Fourier coefficients of the intensity fringes for any grating-to-detector distance, even if it is not a fractional Talbot distance. Results: The developed theory determines the visibility of any diffraction order as a function of the grating-to-detector distance, the phase shift of the grating, and the x-ray spectrum. The authors demonstrate that the visibilities of diffraction orders can serve as the indicators of the underlying interference intensity modulation. Applying the theory to the conventional and inverse geometry configurations of single-grating interferometers, the authors demonstrated that the proposed theory provides a quantitative tool for the grating interferometer optimization with or without the Talbot-distance constraints. Conclusions: In this work, the authors developed a novel theory of the interference intensity fringes in phase grating x-ray interferometry. This theory provides a quantitative tool in design optimization of phase grating x-ray interferometers.

  20. Semiclassical TEM image formation in phase space.

    PubMed

    Lubk, Axel; Röder, Falk

    2015-04-01

    Current developments in TEM such as high-resolution imaging at low acceleration voltages and large fields of view, the ever larger capabilities of hardware aberration correction and the systematic shaping of electron beams require accurate descriptions of TEM imaging in terms of wave optics. Since full quantum mechanic solutions have not yet been established for, e.g., the theory of aberrations, we are exploring semiclassical image formation in the TEM from the perspective of quantum mechanical phase space, here. Firstly, we use two well-known semiclassical approximations, Miller's semiclassical algebra and the frozen Gaussian method, for describing the wave optical generalization of arbitrary geometric aberrations, including nonisoplanatic and slope aberrations. Secondly, we demonstrate that the Wigner function representation of phase space is well suited to also describe incoherent aberrations as well as the ramifications of partial coherence due to the emission process at the electron source. We identify a close relationship between classical phase space and Wigner function distortions due to aberrations as well as classical brightness and quantum mechanical purity. PMID:25579179

  1. Investigating the biochemical progression of liver disease through fibrosis, cirrhosis, dysplasia, and hepatocellular carcinoma using Fourier transform infrared spectroscopic imaging

    NASA Astrophysics Data System (ADS)

    Sreedhar, Hari; Pant, Mamta; Ronquillo, Nemencio R.; Davidson, Bennett; Nguyen, Peter; Chennuri, Rohini; Choi, Jacqueline; Herrera, Joaquin A.; Hinojosa, Ana C.; Jin, Ming; Kajdacsy-Balla, Andre; Guzman, Grace; Walsh, Michael J.

    2014-03-01

    Hepatocellular carcinoma (HCC) is the most common form of primary hepatic carcinoma. HCC ranks the fourth most prevalent malignant tumor and the third leading cause of cancer related death in the world. Hepatocellular carcinoma develops in the context of chronic liver disease and its evolution is characterized by progression through intermediate stages to advanced disease and possibly even death. The primary sequence of hepatocarcinogenesis includes the development of cirrhosis, followed by dysplasia, and hepatocellular carcinoma.1 We addressed the utility of Fourier Transform Infrared (FT-IR) spectroscopic imaging, both as a diagnostic tool of the different stages of the disease and to gain insight into the biochemical process associated with disease progression. Tissue microarrays were obtained from the University of Illinois at Chicago tissue bank consisting of liver explants from 12 transplant patients. Tissue core biopsies were obtained from each explant targeting regions of normal, liver cell dysplasia including large cell change and small cell change, and hepatocellular carcinoma. We obtained FT-IR images of these tissues using a modified FT-IR system with high definition capabilities. Firstly, a supervised spectral classifier was built to discriminate between normal and cancerous hepatocytes. Secondly, an expanded classifier was built to discriminate small cell and large cell changes in liver disease. With the emerging advances in FT-IR instrumentation and computation there is a strong drive to develop this technology as a powerful adjunct to current histopathology approaches to improve disease diagnosis and prognosis.

  2. Fourier Transform Infrared Imaging Showing Reduced Unsaturated Lipid Content in the Hippocampus of a mouse Model of Alzheimer's Disease

    SciTech Connect

    Leskovjan, A.C.; Kretlow, A.; Miller, L.M.

    2010-04-01

    Polyunsaturated fatty acids are essential to brain functions such as membrane fluidity, signal transduction, and cell survival. It is also thought that low levels of unsaturated lipid in the brain may contribute to Alzheimer's disease (AD) risk or severity. However, it is not known how accumulation of unsaturated lipids is affected in different regions of the hippocampus, which is a central target of AD plaque pathology, during aging. In this study, we used Fourier transform infrared imaging (FTIRI) to visualize the unsaturated lipid content in specific regions of the hippocampus in the PSAPP mouse model of AD as a function of plaque formation. Specifically, the unsaturated lipid content was imaged using the olefinic {double_bond}CH stretching mode at 3012 cm{sup -1}. The axonal, dendritic, and somatic layers of the hippocampus were examined in the mice at 13, 24, 40, and 56 weeks old. Results showed that lipid unsaturation in the axonal layer was significantly increased with normal aging in control (CNT) mice (p < 0.01) but remained low and relatively constant in PSAPP mice. Thus, these findings indicate that unsaturated lipid content is reduced in hippocampal white matter during amyloid pathogenesis and that maintaining unsaturated lipid content early in the disease may be critical in avoiding progression of the disease.

  3. Vacuum compatible sample positioning device for matrix assisted laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometry imaging

    SciTech Connect

    Aizikov, Konstantin; Lin, Tzu-Yung; Smith, Donald F.; Heeren, Ron M. A.; Chargin, David A.; Ivanov, Sergei; O'Connor, Peter B.

    2011-05-15

    The high mass accuracy and resolving power of Fourier transform ion cyclotron resonance mass spectrometers (FT-ICR MS) make them ideal mass detectors for mass spectrometry imaging (MSI), promising to provide unmatched molecular resolution capabilities. The intrinsic low tolerance of FT-ICR MS to RF interference, however, along with typically vertical positioning of the sample, and MSI acquisition speed requirements present numerous engineering challenges in creating robotics capable of achieving the spatial resolution to match. This work discusses a two-dimensional positioning stage designed to address these issues. The stage is capable of operating in {approx}1 x 10{sup -8} mbar vacuum. The range of motion is set to 100 mm x 100 mm to accommodate large samples, while the positioning accuracy is demonstrated to be less than 0.4 micron in both directions under vertical load over the entire range. This device was integrated into three different matrix assisted laser desorption/ionization (MALDI) FT-ICR instruments and showed no detectable RF noise. The ''oversampling'' MALDI-MSI experiments, under which the sample is completely ablated at each position, followed by the target movement of the distance smaller than the laser beam, conducted on the custom-built 7T FT-ICR MS demonstrate the stability and positional accuracy of the stage robotics which delivers high spatial resolution mass spectral images at a fraction of the laser spot diameter.

  4. Vacuum compatible sample positioning device for matrix assisted laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometry imaging

    PubMed Central

    Aizikov, Konstantin; Smith, Donald F.; Chargin, David A.; Ivanov, Sergei; Lin, Tzu-Yung; Heeren, Ron M. A.; O’Connor, Peter B.

    2011-01-01

    The high mass accuracy and resolving power of Fourier transform ion cyclotron resonance mass spectrometers (FT-ICR MS) make them ideal mass detectors for mass spectrometry imaging (MSI), promising to provide unmatched molecular resolution capabilities. The intrinsic low tolerance of FT-ICR MS to RF interference, however, along with typically vertical positioning of the sample, and MSI acquisition speed requirements present numerous engineering challenges in creating robotics capable of achieving the spatial resolution to match. This work discusses a two-dimensional positioning stage designed to address these issues. The stage is capable of operating in ∼1 × 10–8 mbar vacuum. The range of motion is set to 100 mm × 100 mm to accommodate large samples, while the positioning accuracy is demonstrated to be less than 0.4 micron in both directions under vertical load over the entire range. This device was integrated into three different matrix assisted laser desorption/ionization (MALDI) FT-ICR instruments and showed no detectable RF noise. The “oversampling” MALDI-MSI experiments, under which the sample is completely ablated at each position, followed by the target movement of the distance smaller than the laser beam, conducted on the custom-built 7T FT-ICR MS demonstrate the stability and positional accuracy of the stage robotics which delivers high spatial resolution mass spectral images at a fraction of the laser spot diameter. PMID:21639522

  5. Phase extraction algorithm considering high-order harmonics in fringe image processing.

    PubMed

    Zhang, Keming; Yao, Jun; Chen, Jubing; Miao, Hong

    2015-06-01

    A phase calculation method using discrete Fourier series (DFS) is proposed to eliminate the effects of nonsinusoidal characteristics. In this method, the fundamental coefficients are extracted from continuous N samples in one cycle by DFS, with which four images with π/2 intervals are reconstructed, and then more accurate phase distribution can be further obtained. This method is applicable for improving the precision of the traditional phase-shifting algorithm. Its effectiveness and accuracy are verified by computer simulations and moiré fringe and projecting fringe experiments with about 85% of the phase error reduced compared with a four-step phase-shifting algorithm, about 70% reduction compared with a 16-step phase-shifting algorithm. PMID:26192656

  6. Analysis of the nutritional status of algae by Fourier transform infrared chemical imaging

    NASA Astrophysics Data System (ADS)

    Hirschmugl, Carol J.; Bayarri, Zuheir-El; Bunta, Maria; Holt, Justin B.; Giordano, Mario

    2006-09-01

    A new non-destructive method to study the nutritional status of algal cells and their environments is demonstrated. This approach allows rapid examination of whole cells without any or little pre-treatment providing a large amount of information on the biochemical composition of cells and growth medium. The method is based on the analysis of a collection of infrared (IR) spectra for individual cells; each spectrum describes the biochemical composition of a portion of a cell; a complete set of spectra is used to reconstruct an image of the entire cell. To obtain spatially resolved information synchrotron radiation was used as a bright IR source. We tested this method on the green flagellate Euglena gracilis; a comparison was conducted between cells grown in nutrient replete conditions (Type 1) and on cells allowed to deplete their medium (Type 2). Complete sets of spectra for individual cells of both types were analyzed with agglomerative hierarchical clustering, leading to distinct clusters representative of the two types of cells. The average spectra for the clusters confirmed the similarities between the clusters and the types of cells. The clustering analysis, therefore, allows the distinction of cells of the same species, but with different nutritional histories. In order to facilitate the application of the method and reduce manipulation (washing), we analyzed the cells in the presence of residual medium. The results obtained showed that even with residual medium the outcome of the clustering analysis is reliable. Our results demonstrate the applicability FTIR microspectroscopy for ecological and ecophysiological studies.

  7. A tilt-compensated Fourier transform spectrometer with an image rotator

    NASA Astrophysics Data System (ADS)

    Wei, Ruyi; Yin, Bangsheng

    2015-07-01

    Due to the moving plane mirror, tilt compensation is crucial and challenging in designing high precision Michelson-type interferometers. In this paper, we propose an optical configuration design using an image rotator and plane mirrors, including a movable double-sided mirror (DSM) to balance out the tilt of the mirror. We analysed the optical path differences (OPD) caused by the tilt of the DSM and their effects on interferogram under different tilt cases. Analyses demonstrate that this design is able to cancel out the offset of the OPD introduced by the tilt pitch angle. For different incident rays in parallel, the position of the tilt centre has no relationship with the change of the OPD, implying that the OPD could be self-compensated, and the modulation of the interferogram will not be degraded due to the tilt. This configuration effectively relaxes the requirements on the control of the precision of the postures of the moving mirror and thus may have broad applications.

  8. The Fourier Imaging X-ray Spectrometer (FIXS) for the Argentinian, Scout-launched satelite de Aplicaciones Cienficas-1 (SAC-1)

    NASA Technical Reports Server (NTRS)

    Dennis, Brian R.; Crannell, Carol JO; Desai, Upendra D.; Orwig, Larry E.; Kiplinger, Alan L.; Schwartz, Richard A.; Hurford, Gordon J.; Emslie, A. Gordon; Machado, Marcos; Wood, Kent

    1988-01-01

    The Fourier Imaging X-ray Spectrometer (FIXS) is one of four instruments on SAC-1, the Argentinian satellite being proposed for launch by NASA on a Scout rocket in 1992/3. The FIXS is designed to provide solar flare images at X-ray energies between 5 and 35 keV. Observations will be made on arcsecond size scales and subsecond time scales of the processes that modify the electron spectrum and the thermal distribution in flaring magnetic structures.

  9. Quantitative phase imaging with programmable illumination

    NASA Astrophysics Data System (ADS)

    Kim, Taewoo; Edwards, Chris; Goddard, Lynford L.; Popescu, Gabriel

    2015-03-01

    Even with the recent rapid advances in the field of microscopy, non-laser light sources used for light microscopy have not been developing significantly. Most current optical microscopy systems use halogen bulbs as their light sources to provide a white-light illumination. Due to the confined shapes and finite filament size of the bulbs, little room is available for modification in the light source, which prevents further advances in microscopy. By contrast, commercial projectors provide a high power output that is comparable to the halogen lamps while allowing for great flexibility in patterning the illumination. In addition to their high brightness, the illumination can be patterned to have arbitrary spatial and spectral distributions. Therefore, commercial projectors can be adopted as a flexible light source to an optical microscope by careful alignment to the existing optical path. In this study, we employed a commercial projector source to a quantitative phase imaging system called spatial light interference microscopy (SLIM), which is an outside module for an existing phase contrast (PC) microscope. By replacing the ring illumination of PC with a ring-shaped pattern projected onto the condenser plane, we were able to recover the same result as the original SLIM. Furthermore, the ring illumination is replaced with multiple dots aligned along the same ring to minimize the overlap between the scattered and unscattered fields. This new method minimizes the halo artifact of the imaging system, which allows for a halo-free high-resolution quantitative phase microscopy system.

  10. Multiple template-based image matching using alpha-rooted quaternion phase correlation

    NASA Astrophysics Data System (ADS)

    DelMarco, Stephen

    2010-04-01

    In computer vision applications, image matching performed on quality-degraded imagery is difficult due to image content distortion and noise effects. State-of-the art keypoint based matchers, such as SURF and SIFT, work very well on clean imagery. However, performance can degrade significantly in the presence of high noise and clutter levels. Noise and clutter cause the formation of false features which can degrade recognition performance. To address this problem, previously we developed an extension to the classical amplitude and phase correlation forms, which provides improved robustness and tolerance to image geometric misalignments and noise. This extension, called Alpha-Rooted Phase Correlation (ARPC), combines Fourier domain-based alpha-rooting enhancement with classical phase correlation. ARPC provides tunable parameters to control the alpha-rooting enhancement. These parameter values can be optimized to tradeoff between high narrow correlation peaks, and more robust wider, but smaller peaks. Previously, we applied ARPC in the radon transform domain for logo image recognition in the presence of rotational image misalignments. In this paper, we extend ARPC to incorporate quaternion Fourier transforms, thereby creating Alpha-Rooted Quaternion Phase Correlation (ARQPC). We apply ARQPC to the logo image recognition problem. We use ARQPC to perform multiple-reference logo template matching by representing multiple same-class reference templates as quaternion-valued images. We generate recognition performance results on publicly-available logo imagery, and compare recognition results to results generated from standard approaches. We show that small deviations in reference templates of sameclass logos can lead to improved recognition performance using the joint matching inherent in ARQPC.

  11. Automation and Control of an Imaging Internal Laser Desorption Fourier Transform Mass Spectrometer (I2LD-FTMS)

    SciTech Connect

    McJunkin, Timothy R; Tranter, Troy Joseph; Scott, Jill Rennee

    2002-06-01

    This paper describes the automation of an imaging internal source laser desorption Fourier transform mass spectrometer (I2LD-FTMS). The I2LD-FTMS consists of a laser-scanning device [Scott and Tremblay, Rev. Sci. Instrum. 2002, 73, 1108–1116] that has been integrated with a laboratory-built FTMS using a commercial data acquisition system (ThermoFinnigan FT/MS, Bremen, Germany). A new user interface has been developed in National Instrument's (Austin, Texas) graphical programming language LabVIEW to control the motors of the laser positioning system and the commercial FTMS data acquisition system. A feature of the FTMS software that allows the user to write macros in a scripting language is used creatively to our advantage in creating a mechanism to control the FTMS from outside its graphical user interface. The new user interface also allows the user to configure target locations. Automation of the data analysis along with data display using commercial graphing software is also described.

  12. Phased Array Feed Calibration, Beamforming, and Imaging

    NASA Astrophysics Data System (ADS)

    Landon, Jonathan; Elmer, Michael; Waldron, Jacob; Jones, David; Stemmons, Alan; Jeffs, Brian D.; Warnick, Karl F.; Fisher, J. Richard; Norrod, Roger D.

    2010-03-01

    Phased array feeds (PAFs) for reflector antennas offer the potential for increased reflector field of view and faster survey speeds. To address some of the development challenges that remain for scientifically useful PAFs, including calibration and beamforming algorithms, sensitivity optimization, and demonstration of wide field of view imaging, we report experimental results from a 19 element room temperature L-band PAF mounted on the Green Bank 20 Meter Telescope. Formed beams achieved an aperture efficiency of 69% and a system noise temperature of 66 K. Radio camera images of several sky regions are presented. We investigate the noise performance and sensitivity of the system as a function of elevation angle with statistically optimal beamforming and demonstrate cancelation of radio frequency interference sources with adaptive spatial filtering.

  13. PHASED ARRAY FEED CALIBRATION, BEAMFORMING, AND IMAGING

    SciTech Connect

    Landon, Jonathan; Elmer, Michael; Waldron, Jacob; Jones, David; Stemmons, Alan; Jeffs, Brian D.; Warnick, Karl F.; Richard Fisher, J.; Norrod, Roger D.

    2010-03-15

    Phased array feeds (PAFs) for reflector antennas offer the potential for increased reflector field of view and faster survey speeds. To address some of the development challenges that remain for scientifically useful PAFs, including calibration and beamforming algorithms, sensitivity optimization, and demonstration of wide field of view imaging, we report experimental results from a 19 element room temperature L-band PAF mounted on the Green Bank 20 Meter Telescope. Formed beams achieved an aperture efficiency of 69% and a system noise temperature of 66 K. Radio camera images of several sky regions are presented. We investigate the noise performance and sensitivity of the system as a function of elevation angle with statistically optimal beamforming and demonstrate cancelation of radio frequency interference sources with adaptive spatial filtering.

  14. Image reconstruction algorithm for recovering high-frequency information in parallel phase-shifting digital holography [Invited].

    PubMed

    Xia, Peng; Shimozato, Yuki; Tahara, Tatsuki; Kakue, Takashi; Awatsuji, Yasuhiro; Nishio, Kenzo; Ura, Shogo; Kubota, Toshihiro; Matoba, Osamu

    2013-01-01

    We propose an image reconstruction algorithm for recovering high-frequency information in parallel phase-shifting digital holography. The proposed algorithm applies three kinds of interpolations and generates three different kinds of object waves. A Fourier transform is applied to each object wave, and the spatial-frequency domain is divided into 3×3 segments for each Fourier-transformed object wave. After that the segment in which interpolation error is the least among the segments having the same address of the segment in the spatial-frequency domain is extracted. The extracted segments are combined to generate an information-enhanced spatial-frequency spectrum of the object wave, and after that the formed spatial-frequency spectrum is inversely Fourier transformed. Then the high-frequency information of the reconstructed image is recovered. The effectiveness of the proposed algorithm was verified by a numerical simulation and an experiment. PMID:23292396

  15. Phase error suppression by low-pass filtering for synthetic aperture imaging ladar

    NASA Astrophysics Data System (ADS)

    Sun, Zhiwei; Hou, Peipei; Zhi, Ya'nan; Sun, Jianfeng; Zhou, Yu; Xu, Qian; Lu, Zhiyong; Liu, Liren

    2014-09-01

    Compared to synthetic aperture radar (SAR), synthetic aperture imaging ladar (SAIL) is more sensitive to the phase errors induced by atmospheric turbulence, undesirable line-of-sight translation-vibration and waveform phase error, because the light wavelength is about 3-6 orders of magnitude less than that of the radio frequency. This phase errors will deteriorate the imaging results. In this paper, an algorithm based on low-pass filtering to suppress the phase error is proposed. In this algorithm, the azimuth quadratic phase history with phase error is compensated, then the fast Fourier transform (FFT) is performed in azimuth direction, after the low-pass filtering, the inverse FFT is performed, then the image is reconstructed simultaneously in the range and azimuth direction by the two-dimensional (2D) FFT. The highfrequency phase error can be effectively eliminated hence the imaging results can be optimized by this algorithm. The mathematical analysis by virtue of data-collection equation of side-looking SAIL is presented. The theoretical modeling results are also given. In addition, based on this algorithm, a principle scheme of optical processor is proposed. The verified experiment is performed employing the data obtained from a SAIL demonstrator.

  16. Radiometric Modeling and Calibration of the Geostationary Imaging Fourier Transform Spectrometer (GIFTS)Ground Based Measurement Experiment

    NASA Technical Reports Server (NTRS)

    Tian, Jialin; Smith, William L.; Gazarik, Michael J.

    2008-01-01

    The ultimate remote sensing benefits of the high resolution Infrared radiance spectrometers will be realized with their geostationary satellite implementation in the form of imaging spectrometers. This will enable dynamic features of the atmosphere s thermodynamic fields and pollutant and greenhouse gas constituents to be observed for revolutionary improvements in weather forecasts and more accurate air quality and climate predictions. As an important step toward realizing this application objective, the Geostationary Imaging Fourier Transform Spectrometer (GIFTS) Engineering Demonstration Unit (EDU) was successfully developed under the NASA New Millennium Program, 2000-2006. The GIFTS-EDU instrument employs three focal plane arrays (FPAs), which gather measurements across the long-wave IR (LWIR), short/mid-wave IR (SMWIR), and visible spectral bands. The GIFTS calibration is achieved using internal blackbody calibration references at ambient (260 K) and hot (286 K) temperatures. In this paper, we introduce a refined calibration technique that utilizes Principle Component (PC) analysis to compensate for instrument distortions and artifacts, therefore, enhancing the absolute calibration accuracy. This method is applied to data collected during the GIFTS Ground Based Measurement (GBM) experiment, together with simultaneous observations by the accurately calibrated AERI (Atmospheric Emitted Radiance Interferometer), both simultaneously zenith viewing the sky through the same external scene mirror at ten-minute intervals throughout a cloudless day at Logan Utah on September 13, 2006. The accurately calibrated GIFTS radiances are produced using the first four PC scores in the GIFTS-AERI regression model. Temperature and moisture profiles retrieved from the PC-calibrated GIFTS radiances are verified against radiosonde measurements collected throughout the GIFTS sky measurement period. Using the GIFTS GBM calibration model, we compute the calibrated radiances from data collected during the moon tracking and viewing experiment events. From which, we derive the lunar surface temperature and emissivity associated with the moon viewing measurements.

  17. High resolution imaging Fourier transform spectrometer with no moving components for the measurement of atmospheric trace gases

    NASA Astrophysics Data System (ADS)

    Mortimer, H.

    2014-12-01

    A high resolution Static Imaging Fourier Transform Spectrometer, SIFTS, with no moving parts has been developed for the detection of atmospheric gases. The instrument has been shown to have high spectral resolution (4 cm-1) and temporal resolution (10kHz) resolution in both the mid and near infrared and moderate spectral resolution (14cm-1) in the visible. This instrument has been developed for the remote sensing and in-situ measurements of atmospheric gases. It has been identified that due to the low mass and compact size of the instrument system, that the SIFTS could be deployed as a remote sensing instrument onboard a Earth Observation satellite or Unmanned Aerial Vehicle (UAV), or conversely as a radiosonde instrument for in-situ measurements of atmospheric gases. The technique is based on a static optical configuration whereby light is split into two paths and made to recombine along a focal plane producing an interference pattern. The spectral information is returned using a detector array to digitally capture the interferogram which can then be processed into a spectrum by applying a Fourier transform. As there are no moving components, the speed of measurement is determined by the frame rate of the detector array. Thus, this instrument has a temporal advantage over common Michelson FTIR instruments. Using a high speed Toshiba CCD line array, sensitive over the spectral region of 400 - 1100nm, spectra have been recorded at a rate of one every 100 microseconds. Using an uncooled microbolometer infrared detector array, sensitive over the spectral region of 2 to 15μm, the gases NH3, O3 and CH4 have been used to demonstrate the sensitivity of the SIFTS instrument. It has been shown that the Signal to Noise of the SIFTSMIR is >1200 using an integration time of 77msec. The novel optical design has reduced the optics to only 3 optical components, and the detector array, to generate and measure the interferogram. The experimental performance of the SIFTS instrument has verified the theoretical models, and it has been shown that the spectral resolution in both the Visible and MIR instruments is 4cm-1 and 14cm-1 respectively.

  18. Color image encryption based on color blend and chaos permutation in the reality-preserving multiple-parameter fractional Fourier transform domain

    NASA Astrophysics Data System (ADS)

    Lang, Jun

    2015-03-01

    In this paper, we propose a novel color image encryption method by using Color Blend (CB) and Chaos Permutation (CP) operations in the reality-preserving multiple-parameter fractional Fourier transform (RPMPFRFT) domain. The original color image is first exchanged and mixed randomly from the standard red-green-blue (RGB) color space to R‧G‧B‧ color space by rotating the color cube with a random angle matrix. Then RPMPFRFT is employed for changing the pixel values of color image, three components of the scrambled RGB color space are converted by RPMPFRFT with three different transform pairs, respectively. Comparing to the complex output transform, the RPMPFRFT transform ensures that the output is real which can save storage space of image and convenient for transmission in practical applications. To further enhance the security of the encryption system, the output of the former steps is scrambled by juxtaposition of sections of the image in the reality-preserving multiple-parameter fractional Fourier domains and the alignment of sections is determined by two coupled chaotic logistic maps. The parameters in the Color Blend, Chaos Permutation and the RPMPFRFT transform are regarded as the key in the encryption algorithm. The proposed color image encryption can also be applied to encrypt three gray images by transforming the gray images into three RGB color components of a specially constructed color image. Numerical simulations are performed to demonstrate that the proposed algorithm is feasible, secure, sensitive to keys and robust to noise attack and data loss.

  19. Multicontrast x-ray computed tomography imaging using Talbot-Lau interferometry without phase stepping

    SciTech Connect

    Bevins, Nicholas; Zambelli, Joseph; Li Ke; Qi Zhihua; Chen Guanghong

    2012-01-15

    Purpose: The purpose of this work is to demonstrate that multicontrast computed tomography (CT) imaging can be performed using a Talbot-Lau interferometer without phase stepping, thus allowing for an acquisition scheme like that used for standard absorption CT. Methods: Rather than using phase stepping to extract refraction, small-angle scattering (SAS), and absorption signals, the two gratings of a Talbot-Lau interferometer were rotated slightly to generate a moire pattern on the detector. A Fourier analysis of the moire pattern was performed to obtain separate projection images of each of the three contrast signals, all from the same single-shot of x-ray exposure. After the signals were extracted from the detector data for all view angles, image reconstruction was performed to obtain absorption, refraction, and SAS CT images. A physical phantom was scanned to validate the proposed data acquisition method. The results were compared with a phantom scan using the standard phase stepping approach. Results: The reconstruction of each contrast mechanism produced the expected results. Signal levels and contrasts match those obtained using the phase stepping technique. Conclusions: Absorption, refraction, and SAS CT imaging can be achieved using the Talbot-Lau interferometer without the additional overhead of long scan time and phase stepping.

  20. In-line phase-contrast imaging for strong absorbing objects

    NASA Astrophysics Data System (ADS)

    DeCaro, Liberato; Cedola, Alessia; Giannini, Cinzia; Bukreeva, Inna; Lagomarsino, Stefano

    2008-11-01

    Phase-contrast imaging is one of the most important emerging x-ray imaging techniques. In this work we analyse, from a theoretical point of view, the in-line phase-contrast image formation under general assumptions. The approach is based on wave-optical theory (Fresnel/Kirchoff diffraction integrals) and on the formalism of the mutual coherence function for the evolution of the coherence wavefield properties. Our theoretical model can be applied to phase-contrast imaging realized both by using highly coherent synchrotron radiation and micro-focus x-ray laboratory sources. Thus, the model is suitable for widespread applications, ranging from material science to medical imaging of human body parts. However, it cannot be applied to polychromatic sources, although the validity of the model does not require particularly demanding characteristics of monochromaticity. In addition, for moderate phase gradients, a useful analytical formula of the phase-contrast visibility is derived, based on the a priori knowledge of source size and distance, pixel detector size, defocus distance, material/tissue dielectric susceptibility and characteristic scales of transversal and longitudinal non-uniformities of the material/tissue dielectric susceptibility. Comparisons both with experimental results published by other authors and with simulations based on a Fourier optics approach have been reported, to confirm the validity of the proposed analytical formula.

  1. Multicontrast x-ray computed tomography imaging using Talbot-Lau interferometry without phase stepping

    PubMed Central

    Bevins, Nicholas; Zambelli, Joseph; Li, Ke; Qi, Zhihua; Chen, Guang-Hong

    2012-01-01

    Purpose: The purpose of this work is to demonstrate that multicontrast computed tomography (CT) imaging can be performed using a Talbot-Lau interferometer without phase stepping, thus allowing for an acquisition scheme like that used for standard absorption CT. Methods: Rather than using phase stepping to extract refraction, small-angle scattering (SAS), and absorption signals, the two gratings of a Talbot-Lau interferometer were rotated slightly to generate a moiré pattern on the detector. A Fourier analysis of the moiré pattern was performed to obtain separate projection images of each of the three contrast signals, all from the same single-shot of x-ray exposure. After the signals were extracted from the detector data for all view angles, image reconstruction was performed to obtain absorption, refraction, and SAS CT images. A physical phantom was scanned to validate the proposed data acquisition method. The results were compared with a phantom scan using the standard phase stepping approach. Results: The reconstruction of each contrast mechanism produced the expected results. Signal levels and contrasts match those obtained using the phase stepping technique. Conclusions: Absorption, refraction, and SAS CT imaging can be achieved using the Talbot-Lau interferometer without the additional overhead of long scan time and phase stepping. PMID:22225312

  2. Heralded phase-contrast imaging using an orbital angular momentum phase-filter

    NASA Astrophysics Data System (ADS)

    Aspden, Reuben S.; Morris, Peter A.; He, Ruiqing; Chen, Qian; Padgett, Miles J.

    2016-05-01

    We utilise the position and orbital angular momentum (OAM) correlations between the signal and idler photons generated in the down-conversion process to obtain ghost images of a phase object. By using an OAM phase filter, which is non-local with respect to the object, the images exhibit isotropic edge-enhancement. This imaging technique is the first demonstration of a full-field, phase-contrast imaging system with non-local edge enhancement, and enables imaging of phase objects using significantly fewer photons than standard phase-contrast imaging techniques.

  3. Encrypted imaging based on algebraic implementation of double random phase encoding.

    PubMed

    Nakano, Kazuya; Takeda, Masafumi; Suzuki, Hiroyuki; Yamaguchi, Masahiro

    2014-05-10

    The security of important information captured by sensors and cameras is currently a growing concern as information theft via techniques such as side-channel attacks become increasingly more prevalent. Double random phase encoding (DRPE) is an optical encryption method based on optical Fourier transform that is currently being used to implement secure coherent optical systems. In this paper, we propose a new DRPE implementation for incoherent optical systems based on integral photography that can be applied to "encrypted imaging (EI)" to optically encrypt an image before it is captured by an image sensor. Because the proposed incoherent DRPE is constituted from conventional DRPE by rewriting the optical encryption via discretization and Euler's formula, its security level is the same as that of conventional DRPE. The results of an experiment in which we encrypted a plaintext image optically and then decrypted it numerically demonstrate that our proposed incoherent optical security system is feasible. PMID:24922013

  4. A simple public-key attack on phase-truncation-based double-images encryption system

    NASA Astrophysics Data System (ADS)

    Ding, Xiangling; Yang, Gaobo; He, Dajiang

    2015-07-01

    Phase-truncation based double-images cryptosystem can avoid the iterative Fourier transforms and realize double-images encryption. In this paper, a simple public-key attack is proposed to break this cryptosystem by using arbitrary position parameters and three public keys. The attack process is composed of two steps. Firstly, the decryption keys are simply generated with the help of arbitrary position parameters and the three public keys. Secondly, the two approximate values of the original images are obtained by using the generated decryption keys. Moreover, the proposed public-key attack is different from the existing attacks. It is not sensitive to position parameters of the double-images and the computing efficiency is also much better. Computer simulation results further prove its vulnerability.

  5. Experimental modules covering imaging, diffraction, Fourier optics and polarization based on a liquid-crystal cell SLM

    NASA Astrophysics Data System (ADS)

    Hermerschmidt, Andreas

    2009-06-01

    In close collaboration with four German universities, we have developed tutorials for experiments based on a transmissive liquid-crystal spatial light modulator (SLM). The experimental tutorials are grouped in six project modules, which cover a wide range of phenomena and have different levels of difficulty. At a basic level, students can investigate the SLM in its probably most well-known application as an image-generating element in a simple optical projector setup. At more advanced levels, the application as an adaptive optical element can be investigated in three different projects covering wave-optical phenomena. The fields covered include Fourier Optics using the SLM as a dynamic fan-out beam-splitter or kinoform, Computer-Generated Holography and basic Interferometry. For the support of these projects, software was developed which permits the generation of adaptive optical structures by the student with a user-friendly interface, while the underlying algorithms are explained in the theoretical tutorial. The modulation of the light by the twisted-neumatic liquid crystal cells of the SLM can be investigated in the two most advanced projects. In the first one, the parameters of the cell and the components of its Jones matrix can be derived from transmission measurements with rotatable polarizers at a number of different wavelengths. This project gives insight to the Jones matrix calculus at the level required for the analysis. In the second one, the complex-valued transmission of the SLM is determined by measuring the diffraction efficiency of dynamically addressed Ronchi gratings.

  6. Two-dimensional wave-number spectral analysis techniques for phase contrast imaging turbulence imaging data on large helical device.

    PubMed

    Michael, C A; Tanaka, K; Vyacheslavov, L; Sanin, A; Kawahata, K

    2015-09-01

    An analysis method for unfolding the spatially resolved wave-number spectrum and phase velocity from the 2D CO2 laser phase contrast imaging system on the large helical device is described. This is based on the magnetic shear technique which identifies propagation direction from 2D spatial Fourier analysis of images detected by a 6 × 8 detector array. Because the strongest modes have wave-number at the lower end of the instrumental k range, high resolution spectral techniques are necessary to clearly resolve the propagation direction and hence the spatial distribution of fluctuations along the probing laser beam. Multiple-spatial point cross-correlation averaging is applied before calculating the spatial power spectrum. Different methods are compared, and it is found that the maximum entropy method (MEM) gives best results. The possible generation of artifacts from the over-narrowing of spectra are investigated and found not to be a significant problem. The spatial resolution Δρ (normalized radius) around the peak wave-number, for conventional Fourier analysis, is ∼0.5, making physical interpretation difficult, while for MEM, Δρ ∼ 0.1. PMID:26429439

  7. Two-dimensional wave-number spectral analysis techniques for phase contrast imaging turbulence imaging data on large helical device

    NASA Astrophysics Data System (ADS)

    Michael, C. A.; Tanaka, K.; Vyacheslavov, L.; Sanin, A.; Kawahata, K.

    2015-09-01

    An analysis method for unfolding the spatially resolved wave-number spectrum and phase velocity from the 2D CO2 laser phase contrast imaging system on the large helical device is described. This is based on the magnetic shear technique which identifies propagation direction from 2D spatial Fourier analysis of images detected by a 6 × 8 detector array. Because the strongest modes have wave-number at the lower end of the instrumental k range, high resolution spectral techniques are necessary to clearly resolve the propagation direction and hence the spatial distribution of fluctuations along the probing laser beam. Multiple-spatial point cross-correlation averaging is applied before calculating the spatial power spectrum. Different methods are compared, and it is found that the maximum entropy method (MEM) gives best results. The possible generation of artifacts from the over-narrowing of spectra are investigated and found not to be a significant problem. The spatial resolution Δρ (normalized radius) around the peak wave-number, for conventional Fourier analysis, is ˜0.5, making physical interpretation difficult, while for MEM, Δρ ˜ 0.1.

  8. Micro- and macro-attenuated total reflection Fourier transform infrared spectroscopic imaging. Plenary Lecture at the 5th International Conference on Advanced Vibrational Spectroscopy, 2009, Melbourne, Australia.

    PubMed

    Kazarian, Sergei G; Chan, K L Andrew

    2010-05-01

    Fourier transform infrared (FT-IR) spectroscopic imaging has become a very powerful method in chemical analysis. In this review paper we describe a variety of opportunities for obtaining FT-IR images using the attenuated total reflection (ATR) approach and provide an overview of fundamental aspects, accessories, and applications in both micro- and macro-ATR imaging modes. The advantages and versatility of both ATR imaging modes are discussed and the spatial resolution of micro-ATR imaging is demonstrated. Micro-ATR imaging has opened up many new areas of study that were previously precluded by inadequate spatial resolution (polymer blends, pharmaceutical tablets, cross-sections of blood vessels or hair, surface of skin, single live cells, cancerous tissues). Recent applications of ATR imaging in polymer research, biomedical and forensic sciences, objects of cultural heritage, and other complex materials are outlined. The latest advances include obtaining spatially resolved chemical images from different depths within a sample, and surface-enhanced images for macro-ATR imaging have also been presented. Macro-ATR imaging is a valuable approach for high-throughput analysis of materials under controlled environments. Opportunities exist for chemical imaging of dynamic aqueous systems, such as dissolution, diffusion, microfluidics, or imaging of dynamic processes in live cells. PMID:20482963

  9. Comparison of retinal thickness by Fourier-domain optical coherence tomography and OCT retinal image analysis software segmentation analysis derived from Stratus optical coherence tomography images

    NASA Astrophysics Data System (ADS)

    Tátrai, Erika; Ranganathan, Sudarshan; Ferencz, Mária; Debuc, Delia Cabrera; Somfai, Gábor Márk

    2011-05-01

    Purpose: To compare thickness measurements between Fourier-domain optical coherence tomography (FD-OCT) and time-domain OCT images analyzed with a custom-built OCT retinal image analysis software (OCTRIMA). Methods: Macular mapping (MM) by StratusOCT and MM5 and MM6 scanning protocols by an RTVue-100 FD-OCT device are performed on 11 subjects with no retinal pathology. Retinal thickness (RT) and the thickness of the ganglion cell complex (GCC) obtained with the MM6 protocol are compared for each early treatment diabetic retinopathy study (ETDRS)-like region with corresponding results obtained with OCTRIMA. RT results are compared by analysis of variance with Dunnett post hoc test, while GCC results are compared by paired t-test. Results: A high correlation is obtained for the RT between OCTRIMA and MM5 and MM6 protocols. In all regions, the StratusOCT provide the lowest RT values (mean difference 43 +/- 8 μm compared to OCTRIMA, and 42 +/- 14 μm compared to RTVue MM6). All RTVue GCC measurements were significantly thicker (mean difference between 6 and 12 μm) than the GCC measurements of OCTRIMA. Conclusion: High correspondence of RT measurements is obtained not only for RT but also for the segmentation of intraretinal layers between FD-OCT and StratusOCT-derived OCTRIMA analysis. However, a correction factor is required to compensate for OCT-specific differences to make measurements more comparable to any available OCT device.

  10. Image definition evaluation functions for X-ray crystallography: a new perspective on the phase problem.

    PubMed

    Li, Hui; He, Meng; Zhang, Ze

    2015-09-01

    The core theme of X-ray crystallography is reconstructing the electron-density distribution of crystals under the constraints of observed diffraction data. Nevertheless, reconstruction of the electron-density distribution by straightforward Fourier synthesis is usually hindered due to the well known phase problem and the finite resolution of diffraction data. In analogy with optical imaging systems, the reconstructed electron-density map may be regarded as the image of the real electron-density distribution in crystals. Inspired by image definition evaluation functions applied in the auto-focusing process, two evaluation functions are proposed for the reconstructed electron-density images. One of them is based on the atomicity of the electron-density distribution and properties of Fourier synthesis. Tests were performed on synthetic data of known structures, and it was found that this evaluation function can distinguish the correctly reconstructed electron-density image from wrong ones when diffraction data of atomic resolution are available. An algorithm was established based on this evaluation function and applied in reconstructing the electron-density image from the synthetic data of known structures. The other evaluation function, which is based on the positivity of electron density and constrained power spectrum entropy maximization, was designed for cases where only diffraction data of rather limited resolution are available. Tests on the synthetic data indicate that this evaluation function may identify the correct phase set even for a data set with resolution as low as 3.5 Å. Though no algorithm for structure solution has been figured out based on the latter function, the results presented here provide a new perspective on the phase problem. PMID:26317195

  11. Simultaneous birefringence imaging and depth phase resolved measurement using a Fourier domain OCT system

    NASA Astrophysics Data System (ADS)

    Briones-R., Manuel de J.; De La Torre-Ibarra, Manuel H.; Mendoza-Santoyo, Fernando; Pedroza-G., Jesús

    2015-05-01

    A low cost optical coherence tomography (OCT) system to measure simultaneously the birefringence and the internal deformation of a porcine cornea is proposed. The optical system uses polarized light to recover simultaneously the s and p polarization states while a couple of cameras record a fringe pattern that serves to reconstruct the internal structure of the cornea. The p and s interference signals are registered separately in each 2D CMOS array which generates in a single shot an entire B-scan, a feature that allows the tracking of non-repeatable deformations. A birefringence map is generated within the tissue when the p and s polarization states are combined. The experiments were conducted on a cornea that is deformed using a hydro static pressure rig which introduces mechanical micro deformations on it, and the results show concomitantly the micro structure of the cornea, its birefringence and the mechanical micro deformation.

  12. Structured illumination quantitative phase microscopy for enhanced resolution amplitude and phase imaging

    PubMed Central

    Chowdhury, Shwetadwip; Izatt, Joseph

    2013-01-01

    Structured illumination microscopy (SIM) is an established microscopy technique typically used to image samples at resolutions beyond the diffraction limit. Until now, however, achieving sub-diffraction resolution has predominantly been limited to intensity-based imaging modalities. Here, we introduce an analogue to conventional SIM that allows sub-diffraction resolution, quantitative phase-contrast imaging of optically transparent objects. We demonstrate sub-diffraction resolution amplitude and quantitative-phase imaging of phantom targets and enhanced resolution quantitative-phase imaging of cells. We report a phase accuracy to within 5% and phase noise of 0.06 rad. PMID:24156044

  13. Phase Retrieval Using a Genetic Algorithm on the Systematic Image-Based Optical Alignment Testbed

    NASA Technical Reports Server (NTRS)

    Taylor, Jaime R.

    2003-01-01

    NASA s Marshall Space Flight Center s Systematic Image-Based Optical Alignment (SIBOA) Testbed was developed to test phase retrieval algorithms and hardware techniques. Individuals working with the facility developed the idea of implementing phase retrieval by breaking the determination of the tip/tilt of each mirror apart from the piston motion (or translation) of each mirror. Presented in this report is an algorithm that determines the optimal phase correction associated only with the piston motion of the mirrors. A description of the Phase Retrieval problem is first presented. The Systematic Image-Based Optical Alignment (SIBOA) Testbeb is then described. A Discrete Fourier Transform (DFT) is necessary to transfer the incoming wavefront (or estimate of phase error) into the spatial frequency domain to compare it with the image. A method for reducing the DFT to seven scalar/matrix multiplications is presented. A genetic algorithm is then used to search for the phase error. The results of this new algorithm on a test problem are presented.

  14. The objective evaluation of the phase image: a comparison of different automated methods.

    PubMed

    Liehn, J C; Hannequin, P; Fortier, A; Elaerts, J; Valeyre, J

    1986-09-01

    One hundred and twenty eight patients with suspected or proven CAD were investigated using both X-ray ventriculography and equilibrium gated radionuclide angiography. In order to diagnose regional wall motion abnormalities, the parametric images obtained by Fourier analysis of the radionuclide images were analysed by different automated methods based on the measurement of the homogeneity of the phase values within the LV ROI. The effect of a diastolic frames exclusion, smoothing the original data, weighting the phase histogram, using Bacharach's error corrected phase distribution functions, using different descriptors of the spread of the phase histograms or distribution functions were tested. Using the results of the X-ray examination as the gold standard, ROC curves were plotted for each method. The ROC curves were modelled by a binormal model using the maximum likelihood method. Statistical tests were applied on the area under the ROC curves. The results show that the diagnostic value of the automated methods depends mainly on the way the histograms or distribution functions are described and to a lesser extent on the type of histograms or distribution functions used. The best result is obtained after smoothing, diastolic frames exclusion, weighting the phase histogram by the amplitude and describing it by its standard deviation. Nevertheless, this result is not significantly different from the result obtained by visual analysis of the phase and amplitude images. PMID:3022218

  15. X-ray phase imaging with a paper analyzer

    SciTech Connect

    Morgan, Kaye S.; Paganin, David M.; Siu, Karen K. W.

    2012-03-19

    We present a simple x-ray phase imaging method that utilizes the sample-induced distortion of a high contrast random intensity pattern to quantitatively retrieve the two-dimensional phase map at the exit surface of a coherently illuminated sample. This reference pattern is created by placing a sheet of sandpaper in the x-ray beam, with the sample-induced distortion observed after propagation to the detector, a meter downstream. Correlation analysis comparing a single ''sample and sandpaper'' image to a reference ''sandpaper only'' image produces two sensitive differential phase contrast images, giving the sample phase gradient in vertical and horizontal directions. These images are then integrated to recover the projected phase depth of the sample. The simple experimental set-up, retention of flux, and the need for only a single sample image per reconstruction suggest that this method is of value in imaging a range of dynamic processes at both synchrotron and laboratory x-ray sources.

  16. Fourier analysis of a gated blood-pool study during atrial flutter

    SciTech Connect

    Makler, P.T. Jr.; McCarthy, D.M.; London, J.W.; Sandler, M.S.; Alavi, A.

    1983-08-01

    First-harmonic Fourier analysis of a gated blood-pool study is based on the assumption that the cardiac chambers contract once per cardiac cycle. In atrial arrhythmias this condition may not exist for the atria. We recently studied a patient with atrial flutter and 2:1 artioventricular conduction. There were predictable alterations in the first-harmonic Fourier phase and amplitude images. The observed changes from first-harmonic Fourier analysis were: (a) very low atrial amplitude values, and (b) absence of identifiable atrial regions on the phase image.

  17. PRECL: A new method for interferometry imaging from closure phase

    NASA Astrophysics Data System (ADS)

    Ikeda, Shiro; Tazaki, Fumie; Akiyama, Kazunori; Hada, Kazuhiro; Honma, Mareki

    2016-06-01

    For short-wavelength VLBI observations, it is difficult to measure the phase of the visibility function accurately. The closure phases are reliable measurements under this situation, though it is not sufficient to retrieve all of the phase information. We propose a new method, phase retrieval from closure phase (PRECL). PRECL estimates all the visibility phases only from the closure phases. Combining PRECL with a sparse modeling method we have already proposed, the imaging process of VLBI does not rely on a dirty image or self-calibration. The proposed method is tested numerically and the results are promising.

  18. PRECL: A new method for interferometry imaging from closure phase

    NASA Astrophysics Data System (ADS)

    Ikeda, Shiro; Tazaki, Fumie; Akiyama, Kazunori; Hada, Kazuhiro; Honma, Mareki

    2016-04-01

    For short-wavelength VLBI observations, it is difficult to measure the phase of the visibility function accurately. The closure phases are reliable measurements under this situation, though it is not sufficient to retrieve all of the phase information. We propose a new method, phase retrieval from closure phase (PRECL). PRECL estimates all the visibility phases only from the closure phases. Combining PRECL with a sparse modeling method we have already proposed, the imaging process of VLBI does not rely on a dirty image or self-calibration. The proposed method is tested numerically and the results are promising.

  19. Development of a phase-sensitive Fourier domain optical coherence tomography system to measure mouse organ of Corti vibrations in two cochlear turns

    NASA Astrophysics Data System (ADS)

    Ramamoorthy, Sripriya; Zhang, Yuan; Petrie, Tracy; Jacques, Steven; Wang, Ruikang; Nuttall, Alfred L.

    2015-12-01

    In this study, we have developed a phase-sensitive Fourier-domain optical coherence tomography system to simultaneously measure the in vivo inner ear vibrations in the hook area and second turn of the mouse cochlea. This technical development will enable measurement of intra-cochlear distortion products at ideal locations such as the distortion product generation site and reflection site. This information is necessary to un-mix the complex mixture of intra-cochlear waves comprising the DPOAE and thus leads to the non-invasive identification of the local region of cochlear damage.

  20. Real-time measurement of alveolar size and population using phase contrast x-ray imaging

    PubMed Central

    Leong, Andrew F.T.; Buckley, Genevieve A.; Paganin, David M.; Hooper, Stuart B.; Wallace, Megan J.; Kitchen, Marcus J.

    2014-01-01

    Herein a propagation-based phase contrast x-ray imaging technique for measuring particle size and number is presented. This is achieved with an algorithm that utilizes the Fourier space signature of the speckle pattern associated with the images of particles. We validate this algorithm using soda-lime glass particles, demonstrating its effectiveness on random and non-randomly packed particles. This technique is then applied to characterise lung alveoli, which are difficult to measure dynamically in vivo with current imaging modalities due to inadequate temporal resolution and/or depth of penetration and field-of-view. We obtain an important result in that our algorithm is able to measure changes in alveolar size on the micron scale during ventilation and shows the presence of alveolar recruitment/de-recruitment in newborn rabbit kittens. This technique will be useful for ventilation management and lung diagnostic procedures. PMID:25426328

  1. Quantitative phase imaging of Breast cancer cell based on SLIM

    NASA Astrophysics Data System (ADS)

    Wu, Huaqin; Li, Zhifang; Li, Hui; Wu, Shulian

    2016-02-01

    We illustrated a novel optical microscopy technique to observe cell dynamics via spatial light interference microscopy (SLIM). SLIM combines Zemike's phase contrast microscopy and Gabor's holography. When the light passes through the transparent specimens, it could render high contrast intensity and record the phase information from the object. We reconstructed the Breast cancer cell phase image by SLIM and the reconstruction algorithm. Our investigation showed that SLIM has the ability to achieve the quantitative phase imaging (QPI).

  2. Effect of noise on modulation amplitude and phase in frequency-domain diffusive imaging.

    PubMed

    Kang, Dongyel; Kupinski, Matthew A

    2012-01-01

    We theoretically investigate the effect of noise on frequency-domain heterodyne and/or homodyne measurements of intensity-modulated beams propagating through diffusive media, such as a photon density wave. We assumed that the attenuated amplitude and delayed phase are estimated by taking the Fourier transform of the noisy, modulated output data. We show that the estimated amplitude and phase are biased when the number of output photons is small. We also show that the use of image intensifiers for photon amplification in heterodyne or homodyne measurements increases the amount of biases. Especially, it turns out that the biased estimation is independent of AC-dependent noise in sinusoidal heterodyne or homodyne outputs. Finally, the developed theory indicates that the previously known variance model of modulation amplitude and phase is not valid in low light situations. Monte-Carlo simulations with varied numbers of input photons verify our theoretical trends of the bias. PMID:22352660

  3. Quantitative phase imaging in flows with high resolution holographic diffraction grating.

    PubMed

    Desse, Jean-Michel; Picart, Pascal; Olchewsky, François

    2015-09-01

    This paper proposes quantitative phase imaging by using a high resolution holographic grating for generating a four-wave shearing interferogram. The high-resolution holographic grating is designed in a "kite" configuration so as to avoid parasitic mixing of diffraction orders. The selection of six diffraction orders in the Fourier spectrum of the interferogram allows reconstructing phase gradients along specific directions. The spectral analysis yields the useful parameters of the reconstruction process. The derivative axes are exactly determined whatever the experimental configurations of the holographic grating. The integration of the derivative yields the phase and the optical thickness. Demonstration of the proposed approach is carried out for the case of the analysis of the supersonic flow of a small vertical jet, 5.56mm in diameter. The experimental results compared with those obtained with digital holography exhibit a very good agreement. PMID:26368468

  4. Quantitative evaluation of phase processing approaches in susceptibility weighted imaging

    NASA Astrophysics Data System (ADS)

    Li, Ningzhi; Wang, Wen-Tung; Sati, Pascal; Pham, Dzung L.; Butman, John A.

    2012-03-01

    Susceptibility weighted imaging (SWI) takes advantage of the local variation in susceptibility between different tissues to enable highly detailed visualization of the cerebral venous system and sensitive detection of intracranial hemorrhages. Thus, it has been increasingly used in magnetic resonance imaging studies of traumatic brain injury as well as other intracranial pathologies. In SWI, magnitude information is combined with phase information to enhance the susceptibility induced image contrast. Because of global susceptibility variations across the image, the rate of phase accumulation varies widely across the image resulting in phase wrapping artifacts that interfere with the local assessment of phase variation. Homodyne filtering is a common approach to eliminate this global phase variation. However, filter size requires careful selection in order to preserve image contrast and avoid errors resulting from residual phase wraps. An alternative approach is to apply phase unwrapping prior to high pass filtering. A suitable phase unwrapping algorithm guarantees no residual phase wraps but additional computational steps are required. In this work, we quantitatively evaluate these two phase processing approaches on both simulated and real data using different filters and cutoff frequencies. Our analysis leads to an improved understanding of the relationship between phase wraps, susceptibility effects, and acquisition parameters. Although homodyne filtering approaches are faster and more straightforward, phase unwrapping approaches perform more accurately in a wider variety of acquisition scenarios.

  5. Analysis and measurement of the modulation transfer function of harmonic shear wave induced phase encoding imaging.

    PubMed

    McAleavey, Stephen A

    2014-05-01

    Shear wave induced phase encoding (SWIPE) imaging generates ultrasound backscatter images of tissue-like elastic materials by using traveling shear waves to encode the lateral position of the scatters in the phase of the received echo. In contrast to conventional ultrasound B-scan imaging, SWIPE offers the potential advantages of image formation without beam focusing or steering from a single transducer element, lateral resolution independent of aperture size, and the potential to achieve relatively high lateral resolution with low frequency ultrasound. Here a Fourier series description of the phase modulated echo signal is developed, demonstrating that echo harmonics at multiples of the shear wave frequency reveal target k-space data at identical multiples of the shear wavenumber. Modulation transfer functions of SWIPE imaging systems are calculated for maximum shear wave acceleration and maximum shear constraints, and compared with a conventionally focused aperture. The relative signal-to-noise ratio of the SWIPE method versus a conventionally focused aperture is found through these calculations. Reconstructions of wire targets in a gelatin phantom using 1 and 3.5 MHz ultrasound and a cylindrical shear wave source are presented, generated from the fundamental and second harmonic of the shear wave modulation frequency, demonstrating weak dependence of lateral resolution with ultrasound frequency. PMID:24815265

  6. Resolution enhancement phase-contrast imaging by microsphere digital holography

    NASA Astrophysics Data System (ADS)

    Wang, Yunxin; Guo, Sha; Wang, Dayong; Lin, Qiaowen; Rong, Lu; Zhao, Jie

    2016-05-01

    Microsphere has shown the superiority of super-resolution imaging in the traditional 2D intensity microscope. Here a microsphere digital holography approach is presented to realize the resolution enhancement phase-contrast imaging. The system is designed by combining the microsphere with the image-plane digital holography. A microsphere very close to the object can increase the resolution by transforming the object wave from the higher frequency to the lower one. The resolution enhancement amplitude and phase images can be retrieved from a single hologram. The experiments are carried on the 1D and 2D gratings, and the results demonstrate that the observed resolution has been improved, meanwhile, the phase-contrast image is obtained. The proposed method can improve the transverse resolution in all directions based on a single exposure. Furthermore, this system has extended the application of the microsphere from the conventional 2D microscopic imaging to 3D phase-contrast microscopic imaging.

  7. Characterization of skin abnormalities in a mouse model of osteogenesis imperfecta using high resolution magnetic resonance imaging and Fourier transform infrared imaging spectroscopy.

    PubMed

    Canuto, H C; Fishbein, K W; Huang, A; Doty, S B; Herbert, R A; Peckham, J; Pleshko, N; Spencer, R G

    2012-01-01

    Evaluation of the skin phenotype in osteogenesis imperfecta (OI) typically involves biochemical measurements, such as histologic or biochemical assessment of the collagen produced from biopsy-derived dermal fibroblasts. As an alternative, the current study utilized non-invasive magnetic resonance imaging (MRI) microscopy and optical spectroscopy to define biophysical characteristics of skin in an animal model of OI. MRI of skin harvested from control, homozygous oim/oim and heterozygous oim/+ mice demonstrated several differences in anatomic and biophysical properties. Fourier transform infrared imaging spectroscopy (FT-IRIS) was used to interpret observed MRI signal characteristics in terms of chemical composition. Differences between wild-type and OI mouse skin included the appearance of a collagen-depleted lower dermal layer containing prominent hair follicles in the oim/oim mice, accounting for 55% of skin thickness in these. The MRI magnetization transfer rate was lower by 50% in this layer as compared to the upper dermis, consistent with lower collagen content. The MRI transverse relaxation time, T2, was greater by 30% in the dermis of the oim/oim mice compared to controls, consistent with a more highly hydrated collagen network. Similarly, an FT-IRIS-defined measure of collagen integrity was 30% lower in the oim/oim mice. We conclude that characterization of phenotypic differences between the skin of OI and wild-type mice by MRI and FT-IRIS is feasible, and that these techniques provide powerful complementary approaches for the analysis of the skin phenotype in animal models of disease. PMID:21845737

  8. Penetration kinetics of dimethyl sulphoxide and glycerol in dynamic optical clearing of porcine skin tissue in vitro studied by Fourier transform infrared spectroscopic imaging.

    PubMed

    Jiang, Jingying; Boese, Matthias; Turner, Paul; Wang, Ruikang K

    2008-01-01

    By use of a Fourier transform infrared (FTIR) spectroscopic imaging technique, we examine the dynamic optical clearing processes occurring in hyperosmotically biocompatible agents penetrating into skin tissue in vitro. The sequential collection of images in a time series provides an opportunity to assess penetration kinetics of dimethyl sulphoxide (DMSO) and glycerol beneath the surface of skin tissue over time. From 2-D IR spectroscopic images and 3-D false color diagrams, we show that glycerol takes at least 30 min to finally penetrate the layer of epidermis, while DMSO can be detected in epidermis after only 4 min of being topically applied over stratum corneum sides of porcine skin. The results demonstrate the potential of a FTIR spectroscopic imaging technique as an analytical tool for the study of dynamic optical clearing effects when the bio-tissue is impregnated by hyperosmotically biocompatible agents such as glycerol and DMSO. PMID:18465954

  9. Multi-oriented windowed harmonic phase reconstruction for robust cardiac strain imaging.

    PubMed

    Cordero-Grande, Lucilio; Royuela-del-Val, Javier; Sanz-Estébanez, Santiago; Martín-Fernández, Marcos; Alberola-López, Carlos

    2016-04-01

    The purpose of this paper is to develop a method for direct estimation of the cardiac strain tensor by extending the harmonic phase reconstruction on tagged magnetic resonance images to obtain more precise and robust measurements. The extension relies on the reconstruction of the local phase of the image by means of the windowed Fourier transform and the acquisition of an overdetermined set of stripe orientations in order to avoid the phase interferences from structures outside the myocardium and the instabilities arising from the application of a gradient operator. Results have shown that increasing the number of acquired orientations provides a significant improvement in the reproducibility of the strain measurements and that the acquisition of an extended set of orientations also improves the reproducibility when compared with acquiring repeated samples from a smaller set of orientations. Additionally, biases in local phase estimation when using the original harmonic phase formulation are greatly diminished by the one here proposed. The ideas here presented allow the design of new methods for motion sensitive magnetic resonance imaging, which could simultaneously improve the resolution, robustness and accuracy of motion estimates. PMID:26745763

  10. Multi-template image matching using alpha-rooted biquaternion phase correlation with application to logo recognition

    NASA Astrophysics Data System (ADS)

    DelMarco, Stephen

    2011-06-01

    Hypercomplex approaches are seeing increased application to signal and image processing problems. The use of multicomponent hypercomplex numbers, such as quaternions, enables the simultaneous co-processing of multiple signal or image components. This joint processing capability can provide improved exploitation of the information contained in the data, thereby leading to improved performance in detection and recognition problems. In this paper, we apply hypercomplex processing techniques to the logo image recognition problem. Specifically, we develop an image matcher by generalizing classical phase correlation to the biquaternion case. We further incorporate biquaternion Fourier domain alpha-rooting enhancement to create Alpha-Rooted Biquaternion Phase Correlation (ARBPC). We present the mathematical properties which justify use of ARBPC as an image matcher. We present numerical performance results of a logo verification problem using real-world logo data, demonstrating the performance improvement obtained using the hypercomplex approach. We compare results of the hypercomplex approach to standard multi-template matching approaches.

  11. Multivariate Analysis of Attenuated Total Reflection Fourier Transform Infrared (ATR FT-IR) Spectroscopic Data to Confirm Phase Partitioning in Methacrylate-Based Dentin Adhesive

    PubMed Central

    Ye, Qiang; Parthasarathy, Ranganathan; Abedin, Farhana; Laurence, Jennifer S.; Misra, Anil; Spencer, Paulette

    2014-01-01

    Water is ubiquitous in the mouths of healthy individuals and is a major interfering factor in the development of a durable seal between the tooth and composite restoration. Water leads to the formation of a variety of defects in dentin adhesives; these defects undermine the tooth-composite bond. Our group recently analyzed phase partitioning of dentin adhesives using high-performance liquid chromatography (HPLC). The concentration measurements provided by HPLC offered a more thorough representation of current adhesive performance and elucidated directions to be taken for further improvement. The sample preparation and instrument analysis using HPLC are, however, time-consuming and labor-intensive. The objective of this work was to develop a methodology for rapid, reliable, and accurate quantitative analysis of near-equilibrium phase partitioning in adhesives exposed to conditions simulating the wet oral environment. Analysis by Fourier transform infrared (FT-IR) spectroscopy in combination with multivariate statistical methods, including partial least squares (PLS) regression and principal component regression (PCR), were used for multivariate calibration to quantify the compositions in separated phases. Excellent predictions were achieved when either the hydrophobic-rich phase or the hydrophilic-rich phase mixtures were analyzed. These results indicate that FT-IR spectroscopy has excellent potential as a rapid method of detection and quantification of dentin adhesives that experience phase separation under conditions that simulate the wet oral environment. PMID:24359662

  12. Optical cryptosystem of color images using random phase masks in the fractional wavelet transform domain

    NASA Astrophysics Data System (ADS)

    Singh, Hukum

    2016-05-01

    An optical color image encryption in the Fractional Wavelet Transform (FWT) domain is carried out. The original images are segregated into three colors components: R (red), G (green) and B (blue). After that the components are encrypted separately using double random phase encoding (DRPE) in the FWT domain. Random phase masks (RPMs) are used in the input as well as in Fourier plane. The images to be encrypted are transformed with the discrete wavelet transform (DWT), the resulting coefficients from the DWT are multiplied each one by masks different form RPM. Masks are independent each other and the results are applied an inverse discrete Wavelet Transform (IDWT), obtaining the encrypted images. The input images are recovered from their corresponding encrypted images by using the correct parameters of the FWT, and its digital implementation has been performed using MATLAB 7.6.0 (R2008a). The mother wavelet family and fractional orders associated with the FWT are extra keys that access difficulty an attacker; thereby the scheme is more secure as compared to conventional techniques. The sensitivity of proposed scheme is verified with encryption parameters, occlusions, and noise attacks.

  13. Phase contrast without phase plates and phase rings--optical solutions for improved imaging of phase structures.

    PubMed

    Piper, Timm; Piper, Jörg

    2013-10-01

    Using the optical methods described, phase specimens can be observed with a modified light microscope in enhanced clarity, purified from typical artifacts which are apparent in standard phase contrast illumination. In particular, haloing and shade-off are absent, lateral and vertical resolution are maximized and the image quality remains constant even in problematic preparations which cannot be well examined in normal phase contrast, such as specimens beyond a critical thickness or covered by obliquely situated cover slips. The background brightness and thus the range of contrast can be continuously modulated and specimens can be illuminated in concentric-peripheral, axial or paraxial light. Additional contrast effects can be achieved by spectral color separation. Normal glass or mirror lenses can be used; they do not need to be fitted with a phase plate or a phase ring. The methods described should be of general interest for all disciplines using phase microscopy. PMID:23913620

  14. Magnetic field induced differential neutron phase contrast imaging

    SciTech Connect

    Strobl, M.; Treimer, W.; Walter, P.; Keil, S.; Manke, I.

    2007-12-17

    Besides the attenuation of a neutron beam penetrating an object, induced phase changes have been utilized to provide contrast in neutron and x-ray imaging. In analogy to differential phase contrast imaging of bulk samples, the refraction of neutrons by magnetic fields yields image contrast. Here, it will be reported how double crystal setups can provide quantitative tomographic images of magnetic fields. The use of magnetic air prisms adequate to split the neutron spin states enables a distinction of field induced phase shifts and these introduced by interaction with matter.

  15. Phase tomography from x-ray coherent diffractive imaging projections.

    PubMed

    Guizar-Sicairos, Manuel; Diaz, Ana; Holler, Mirko; Lucas, Miriam S; Menzel, Andreas; Wepf, Roger A; Bunk, Oliver

    2011-10-24

    Coherent diffractive imaging provides accurate phase projections that can be tomographically combined to yield detailed quantitative 3D reconstructions with a resolution that is not limited by imaging optics. We present robust algorithms for post-processing and alignment of these tomographic phase projections. A simple method to remove undesired constant and linear phase terms on the reconstructions is given. Also, we provide an algorithm for automatic alignment of projections that has good performance even for samples with no fiducial markers. Currently applied to phase projections, this alignment algorithm has proven to be robust and should also be useful for lens-based tomography techniques that pursue nanoscale 3D imaging. Lastly, we provide a method for tomographic reconstruction that works on phase projections that are known modulo 2π, such that the phase unwrapping step is avoided. We demonstrate the performance of these algorithms by 3D imaging of bacteria population in legume root-nodule cells. PMID:22108985

  16. Speckle imaging algorithms for planetary imaging

    SciTech Connect

    Johansson, E.

    1994-11-15

    I will discuss the speckle imaging algorithms used to process images of the impact sites of the collision of comet Shoemaker-Levy 9 with Jupiter. The algorithms use a phase retrieval process based on the average bispectrum of the speckle image data. High resolution images are produced by estimating the Fourier magnitude and Fourier phase of the image separately, then combining them and inverse transforming to achieve the final result. I will show raw speckle image data and high-resolution image reconstructions from our recent experiment at Lick Observatory.

  17. Broadband Phase Retrieval for Image-Based Wavefront Sensing

    NASA Technical Reports Server (NTRS)

    Dean, Bruce H.

    2007-01-01

    A focus-diverse phase-retrieval algorithm has been shown to perform adequately for the purpose of image-based wavefront sensing when (1) broadband light (typically spanning the visible spectrum) is used in forming the images by use of an optical system under test and (2) the assumption of monochromaticity is applied to the broadband image data. Heretofore, it had been assumed that in order to obtain adequate performance, it is necessary to use narrowband or monochromatic light. Some background information, including definitions of terms and a brief description of pertinent aspects of image-based phase retrieval, is prerequisite to a meaningful summary of the present development. Phase retrieval is a general term used in optics to denote estimation of optical imperfections or aberrations of an optical system under test. The term image-based wavefront sensing refers to a general class of algorithms that recover optical phase information, and phase-retrieval algorithms constitute a subset of this class. In phase retrieval, one utilizes the measured response of the optical system under test to produce a phase estimate. The optical response of the system is defined as the image of a point-source object, which could be a star or a laboratory point source. The phase-retrieval problem is characterized as image-based in the sense that a charge-coupled-device camera, preferably of scientific imaging quality, is used to collect image data where the optical system would normally form an image. In a variant of phase retrieval, denoted phase-diverse phase retrieval [which can include focus-diverse phase retrieval (in which various defocus planes are used)], an additional known aberration (or an equivalent diversity function) is superimposed as an aid in estimating unknown aberrations by use of an image-based wavefront-sensing algorithm. Image-based phase-retrieval differs from such other wavefront-sensing methods, such as interferometry, shearing interferometry, curvature wavefront sensing, and Shack-Hartmann sensing, all of which entail disadvantages in comparison with image-based methods. The main disadvantages of these non-image based methods are complexity of test equipment and the need for a wavefront reference.

  18. Image quality and dose efficiency of high energy phase sensitive x-ray imaging: Phantom studies

    PubMed Central

    Wong, Molly Donovan; Wu, Xizeng; Liu, Hong

    2014-01-01

    The goal of this preliminary study was to perform an image quality comparison of high energy phase sensitive imaging with low energy conventional imaging at similar radiation doses. The comparison was performed with the following phantoms: American College of Radiology (ACR), contrast-detail (CD), acrylic edge and tissue-equivalent. Visual comparison of the phantom images indicated comparable or improved image quality for all phantoms. Quantitative comparisons were performed through ACR and CD observer studies, both of which indicated higher image quality in the high energy phase sensitive images. The results of this study demonstrate the ability of high energy phase sensitive imaging to overcome existing challenges with the clinical implementation of phase contrast imaging and improve the image quality for a similar radiation dose as compared to conventional imaging near typical mammography energies. In addition, the results illustrate the capability of phase sensitive imaging to sustain the image quality improvement at high x-ray energies and for – breast – simulating phantoms, both of which indicate the potential to benefit fields such as mammography. Future studies will continue to investigate the potential for dose reduction and image quality improvement provided by high energy phase sensitive contrast imaging. PMID:24865208

  19. Phase contrast portal imaging for image-guided microbeam radiation therapy

    NASA Astrophysics Data System (ADS)

    Umetani, Keiji; Kondoh, Takeshi

    2014-03-01

    High-dose synchrotron microbeam radiation therapy is a unique treatment technique used to destroy tumors without severely affecting circumjacent healthy tissue. We applied a phase contrast technique to portal imaging in preclinical microbeam radiation therapy experiments. Phase contrast portal imaging is expected to enable us to obtain higherresolution X-ray images at therapeutic X-ray energies compared to conventional portal imaging. Frontal view images of a mouse head sample were acquired in propagation-based phase contrast imaging. The phase contrast images depicted edge-enhanced fine structures of the parietal bones surrounding the cerebrum. The phase contrast technique is expected to be effective in bony-landmark-based verification for image-guided radiation therapy.

  20. Simple phase extraction in x-ray differential phase contrast imaging

    NASA Astrophysics Data System (ADS)

    Xin, Liu; Jin-Chuan, Guo; Yao-Hu, Lei; Ji, Li; Han-Ben, Niu

    2016-02-01

    A fast and simple method to extract phase-contrast images from interferograms is proposed, and its effectiveness is demonstrated through simulation and experiment. For x-ray differential phase contrast imaging, a strong attenuation signal acts as an overwhelming background intensity that obscures the weak phase signal so that no obvious phase-gradient information is detectable in the raw image. By subtracting one interferogram from another, chosen at particular intervals, the phase signal can be isolated and magnified. Project supported by the National Natural Science Foundation of China (Grant Nos. 61101175, 61571305, and 61227802).

  1. Vortex-enhanced coherent-illumination phase diversity for phase retrieval in coherent imaging systems.

    PubMed

    Echeverri-Chacón, Santiago; Restrepo, René; Cuartas-Vélez, Carlos; Uribe-Patarroyo, Néstor

    2016-04-15

    We propose a phase-retrieval method based on the numerical optimization of a new objective function using coherent phase-diversity images as inputs for the characterization of aberrations in coherent imaging systems. By employing a spatial light modulator to generate multiple-order spiral phase masks as diversities, we obtain an increase in the accuracy of the retrieved phase compared with similar state-of-the-art phase-retrieval techniques that use the same number of input images. We present simulations that show a consistent advantage of our technique, and experimental validation where our implementation is used to characterize a highly aberrated 4F optical system. PMID:27082353

  2. First principles multielectron mixed quantum/classical simulations in the condensed phase. I. An efficient Fourier-grid method for solving the many-electron problem

    NASA Astrophysics Data System (ADS)

    Glover, William J.; Larsen, Ross E.; Schwartz, Benjamin J.

    2010-04-01

    We introduce an efficient multielectron first-principles based electronic structure method, the two-electron Fourier-grid (2EFG) approach, that is particularly suited for use in mixed quantum/classical simulations of condensed-phase systems. The 2EFG method directly solves for the six-dimensional wave function of a two-electron Hamiltonian in a Fourier-grid representation such that the effects of electron correlation and exchange are treated exactly for both the ground and excited states. Due to the simplicity of a Fourier-grid representation, the 2EFG is readily parallelizable and we discuss its computational implementation in a distributed-memory parallel environment. We show our method is highly efficient, being able to find two-electron wave functions in ˜20 s on a modern desktop computer for a calculation this is equivalent to full configuration interaction (FCI) in a basis of 17 million Slater determinants. We benchmark the accuracy of the 2EFG by applying it to two electronic structure test problems: the harmonium atom and the sodium dimer. We find that even with a modest grid basis size, our method converges to the analytically exact solutions of harmonium in both the weakly and strongly correlated electron regimes. Our method also reproduces the low-lying potential energy curves of the sodium dimer to a similar level of accuracy as a valence CI calculation, thus demonstrating its applicability to molecular systems. In the following paper [W. J. Glover, R. E. Larsen, and B. J. Schwartz, J. Chem. Phys. 132, 144102 (2010)], we use the 2EFG method to explore the nature of the electronic states that comprise the charge-transfer-to-solvent absorption band of sodium anions in liquid tetrahydrofuran.

  3. Effect of coherence loss in differential phase contrast imaging

    NASA Astrophysics Data System (ADS)

    Cai, Weixing; Ning, Ruola; Liu, Jiangkun

    2014-03-01

    Coherence property of x-rays is critical in the grating-based differential phase contrast (DPC) imaging because it is the physical foundation that makes any form of phase contrast imaging possible. Loss of coherence is an important experimental issue, which results in increased image noise and reduced object contrast in DPC images and DPC cone beam CT (DPC-CBCT) reconstructions. In this study, experimental results are investigated to characterize the visibility loss (a measurement of coherence loss) in several different applications, including different-sized phantom imaging, specimen imaging and small animal imaging. Key measurements include coherence loss (relative intensity changes in the area of interest in phase-stepping images), contrast and noise level in retrieved DPC images, and contrast and noise level in reconstructed DPC-CBCT images. The influence of size and composition of imaged object (uniform object, bones, skin hairs, tissues, and etc) will be quantified. The same investigation is also applied for moiré pattern-based DPC-CBCT imaging with the same exposure dose. A theoretical model is established to relate coherence loss, noise level in phase stepping images (or moiré images), and the contrast and noise in the retrieved DPC images. Experiment results show that uniform objects lead to a small coherence loss even when the attenuation is higher, while objects with large amount of small structures result in huge coherence loss even when the attenuation is small. The theoretical model predicts the noise level in retrieved DPC images, and it also suggests a minimum dose required for DPC imaging to compensate for coherence loss.

  4. Phase contrast, phase retrieval and aberration balancing in shift-invariant linear imaging systems

    NASA Astrophysics Data System (ADS)

    Paganin, David M.; Gureyev, Timur E.

    2008-03-01

    We treat the problems of phase-contrast image formation, deterministic phase retrieval and aberration balancing, in the imaging of weak objects using two-dimensional shift-invariant linear imaging systems. Three classes of model sample are considered: weak phase objects, weak phase-amplitude objects and single-material weak phase-amplitude objects. For each class of sample we show how the various aberration coefficients, which characterise a given imaging system, contribute to the structure of the associated phase-contrast image. The corresponding inverse problem, of obtaining a closed-form expression for the input wave-field given one or more aberrated phase-contrast images of the same, is then examined. Two sample applications are considered: analyser-crystal phase-contrast imaging of weak objects using hard X-rays, and Zernike-type phase-contrast imaging. We close with a discussion of how coherent and incoherent aberrations may be "balanced" against one another, briefly mentioning the applications of this idea to both "deblur by defocus" and proximity-corrected X-ray lithography.

  5. Digital image encryption and watermarking by phase-shifting interferometry.

    PubMed

    Cai, Lu-Zhong; He, Ming-Zhao; Liu, Qing; Yang, Xiu-Lun

    2004-05-20

    A method for both image encryption and watermarking by three-step phase-shifting interferometry is proposed. The image to be hidden is stored in three interferograms and then can be reconstructed by use of one random phase mask, several specific geometric parameters, and a certain algorithm. To further increase the security of the hidden image and confuse unauthorized receivers, images with the same or different content can be added to the interferograms, and these images will have no or only a small effect on the retrieval of the hidden image, owing to the specific property of this algorithm. All these features and the utility of this method for image retrieval from parts of interferograms are verified by computer simulations. This technique uses intensity maps as decrypted images for delivery, and both encryption and decryption can be conveniently achieved digitally. It is particularly suitable for the remote transmission of secret information via the Internet. PMID:15176196

  6. Improving the resolution of three-dimensional acoustic imaging with planar phased arrays

    NASA Astrophysics Data System (ADS)

    Xenaki, Angeliki; Jacobsen, Finn; Fernandez-Grande, Efren

    2012-04-01

    This paper examines and compares two methods of improving the quality of three-dimensional beamforming with phased microphone arrays. The intended application is the detection of aerodynamic noise sources on wind turbines. Both methods employ Fourier based deconvolution. The first method involves a transformation of coordinates that tends to make the response to a point source, the point spread function, more shift invariant. The result is a significant improvement in sound source imaging in the transformed coordinate system. However, the inverse transformation to Cartesian coordinates introduces range dependent resolution limitations because of the irregular distribution of the focal points. The second method combines the transformation of coordinates with an alternative scanning technique. This method can be used in near field three-dimensional acoustic imaging to produce maps free of sidelobes and with constant resolution. The robustness of the proposed methods is validated both with computer simulations and experimentally.

  7. Motion-compensated hand-held common-path Fourier-domain optical coherence tomography probe for image-guided intervention

    NASA Astrophysics Data System (ADS)

    Huang, Yong; Song, Cheol; Liu, Xuan; Kang, Jin U.

    2013-03-01

    A motion-compensated hand-held common-path Fourier-domain optical coherence tomography imaging probe has been developed for image guided intervention during microsurgery. A hand-held prototype instrument was designed and fabricated by integrating an imaging fiber probe inside a stainless steel needle which is attached to the ceramic shaft of a piezoelectric motor housed in an aluminum handle. The fiber probe obtains A-scan images. The distance information was extracted from the A-scans to track the sample surface distance and a fixed distance was maintained by a feedback motor control which effectively compensated hand tremor and target movements in the axial direction. Graphical user interface, real-time data processing, and visualization based on a CPU-GPU hybrid programming architecture were developed and used in the implantation of this system. To validate the system, free-hand optical coherence tomography images using various samples were obtained. The system can be easily integrated into microsurgical tools and robotics for a wide range of clinical applications. Such tools could offer physicians the freedom to easily image sites of interest with reduced risk and higher image quality.

  8. Phase retrieval in X-ray phase-contrast imaging suitable for tomography.

    PubMed

    Burvall, Anna; Lundström, Ulf; Takman, Per A C; Larsson, Daniel H; Hertz, Hans M

    2011-05-23

    In-line phase-contrast X-ray imaging provides images where both absorption and refraction contribute. For quantitative analysis of these images, the phase needs to be retrieved numerically. There are many phase-retrieval methods available. Those suitable for phase-contrast tomography, i.e., non-iterative phase-retrieval methods that use only one image at each projection angle, all follow the same pattern though derived in different ways. We outline this pattern and use it to compare the methods to each other, considering only phase-retrieval performance and not the additional effects of tomographic reconstruction. We also outline derivations, approximations and assumptions, and show which methods are similar or identical and how they relate to each other. A simple scheme for choosing reconstruction method is presented, and numerical phase-retrieval performed for all methods. PMID:21643293

  9. Development of neutron tomography and phase contrast imaging technique

    SciTech Connect

    Kashyap, Y. S.; Agrawal, Ashish; Sarkar, P. S.; Shukla, Mayank; Sinha, Amar

    2013-02-05

    This paper presents design and development of a state of art neutron imaging technique at CIRUS reactor with special reference for techniques adopted for tomography and phase contrast imaging applications. Different components of the beamline such as collimator, shielding, sample manipulator, digital imaging system were designed keeping in mind the requirements of data acquisition time and resolution. The collimator was designed in such a way that conventional and phase contrast imaging can be done using same collimator housing. We have done characterization of fuel pins, study of hydride blisters in pressure tubes hydrogen based cells, two phase flow visualization, and online study of locomotive parts etc. using neutron tomography and radiography technique. We have also done some studies using neutron phase contrast imaging technique on this beamline.

  10. Phase-retrieval ghost imaging of complex-valued objects

    SciTech Connect

    Gong Wenlin; Han Shensheng

    2010-08-15

    An imaging approach, based on ghost imaging, is reported to recover a pure-phase object or a complex-valued object. Our analytical results, which are backed up by numerical simulations, demonstrate that both the complex-valued object and its amplitude-dependent part can be separately and nonlocally reconstructed using this approach. Both effects influencing the quality of reconstructed images and methods to further improve the imaging quality are also discussed.

  11. Image formation principles in coded-aperture based x-ray phase contrast imaging.

    PubMed

    Olivo, A; Speller, R

    2008-11-21

    A novel x-ray phase contrast imaging technique based on coded apertures was recently developed at University College London. This technique removes most limitations of previous phase contrast methods and provides image improvements comparable to those obtained with synchrotron radiation with conventional x-ray sources. Unlike other phase contrast approaches, the technique does not impose restrictive wavelength and/or angular filtering on the beam emitted by the source, meaning that the beam can be exploited in full thus minimizing exposure times. As a consequence, the method provides, for the first time, a concrete opportunity to transfer x-ray phase contrast imaging into real medical applications. This paper discusses the image formation principles, analyses the shape and nature of the phase contrast profiles obtained and draws a significant conclusion on the role of convolution integrals in the acquisition of phase contrast patterns, applicable also to other phase contrast imaging approaches. PMID:18941282

  12. Phase Difference Application in Fully PolSAR Images

    NASA Astrophysics Data System (ADS)

    Rodionova, N. V.

    2009-04-01

    The probability density function of each phase angle ?pq in complex PolSAR data, follow hypothesis of strong scattering regime, is uniformly distributed over [ - ? , ? ] and therefore does not contain any information about image terrain properties. But interchannel phase information: 1) co-pol phase (the phase difference between the co-polarised channels HH and VV), 2) cross-pol phase (the phase difference between the cross- polarised channels HH and HV, VV and VH), 3) the phase difference between HV and VH channels, are important in SAR polarimetric data along with the intensity. The area of its application in SAR polarimetric images includes the discrimination between dominant scattering situations, crop classification, moving target indication, oil spill observations, forest parameters estimation. This paper represents a brief review of interchannel phase information application in PolSAR imagery, illustrated by images from SIR-C/X-SAR SLC C- and L-band fully polarimetric SAR data of Moscow region and Baikal Lake region, acquired in 1994/10/09. Speckle reduction is one of the main moments in the image interpretation improvement. But it is almost no difference between polarimetric phase difference not filtered or filtered by Lee polarimetric filter. It's not the case for amplitude information in PolSAR images.

  13. A Fourier transform infrared study of the gas-phase reactions of O/sub 3/ with chloroethylenes. Detection of peroxyformic acid

    SciTech Connect

    Niki, H.; Maker, P.D.; Savage, C.M.; Breitenbach, L.P.; Martinez, R.I.; Herron, J.T.

    1982-05-13

    Using the Fourier Transform infrared spectroscopic method, we identified peroxyformic acid among the products formed in the gas-phase reactions of O/sub 3/ with chloroethylenes of the form CHCl=CH/sub x/Cl/sub y/ (0 less than or equal to (x,y) less than or equal to 2). It was concluded that the transient species observed by Hisatsune and Heicklen in the O/sub 3/-CHCl=CHCl system was HC(O)OOH and not the anti conformer of HC(O)OH which they had postulated. The results obtained also suggest that the Criegee intermediate H(Cl)COO. is the precursor of the HC(O)OOH.

  14. Two dimensional vibrations of the guinea pig apex organ of Corti measured in vivo using phase sensitive Fourier domain optical coherence tomography

    NASA Astrophysics Data System (ADS)

    Ramamoorthy, Sripriya; Zhang, Yuan; Petrie, Tracy; Fridberger, Anders; Ren, Tianying; Wang, Ruikang; Jacques, Steven L.; Nuttall, Alfred L.

    2015-02-01

    In this study, we measure the in vivo apical-turn vibrations of the guinea pig organ of Corti in both axial and radial directions using phase-sensitive Fourier domain optical coherence tomography. The apical turn in guinea pig cochlea has best frequencies around 100 - 500 Hz which are relevant for human speech. Prior measurements of vibrations in the guinea pig apex involved opening the otic capsule, which has been questioned on the basis of the resulting changes to cochlear hydrodynamics. Here this limitation is overcome by measuring the vibrations through bone without opening the otic capsule. Furthermore, we have significantly reduced the surgery needed to access the guinea pig apex in the axial direction by introducing a miniature mirror inside the bulla. The method and preliminary data are discussed in this article.

  15. A new imaging technique on strength and phase of pulsatile tissue-motion in brightness-mode ultrasonogram

    NASA Astrophysics Data System (ADS)

    Fukuzawa, Masayuki; Yamada, Masayoshi; Nakamori, Nobuyuki; Kitsunezuka, Yoshiki

    2007-03-01

    A new imaging technique has been developed for observing both strength and phase of pulsatile tissue-motion in a movie of brightness-mode ultrasonogram. The pulsatile tissue-motion is determined by evaluating the heartbeat-frequency component in Fourier transform of a series of pixel value as a function of time at each pixel in a movie of ultrasonogram (640x480pixels/frame, 8bit/pixel, 33ms/frame) taken by a conventional ultrasonograph apparatus (ATL HDI5000). In order to visualize both the strength and the phase of the pulsatile tissue-motion, we propose a pulsatile-phase image that is obtained by superimposition of color gradation proportional to the motion phase on the original ultrasonogram only at which the motion strength exceeds a proper threshold. The pulsatile-phase image obtained from a cranial ultrasonogram of normal neonate clearly reveals that the motion region gives good agreement with the anatomical shape and position of the middle cerebral artery and the corpus callosum. The motion phase is fluctuated with the shape of arteries revealing local obstruction of blood flow. The pulsatile-phase images in the neonates with asphyxia at birth reveal decreases of the motion region and increases of the phase fluctuation due to the weakness and local disturbance of blood flow, which is useful for pediatric diagnosis.

  16. High-speed parallel phase-shifting digital holography system using special-purpose computer for image reconstruction

    NASA Astrophysics Data System (ADS)

    Kakue, Takashi; Shimobaba, Tomoyoshi; Ito, Tomoyoshi

    2015-05-01

    We report a high-speed parallel phase-shifting digital holography system using a special-purpose computer for image reconstruction. Parallel phase-shifting digital holography is a technique capable of single-shot phase-shifting interferometry. This technique records information of multiple phase-shifted holograms required for calculation of phase-shifting interferometry with a single shot by using space-division multiplexing. This technique needs image-reconstruction process for a huge amount of recorded holograms. In particular, it takes a long time to calculate light propagation based on fast Fourier transform in the process and to obtain a motion picture of a dynamically and fast moving object. Then we designed a special-purpose computer for accelerating the image-reconstruction process of parallel phase-shifting digital holography. We developed a special-purpose computer consisting of VC707 evaluation kit (Xilinx Inc.) which is a field programmable gate array board. We also recorded holograms consisting of 128 × 128 pixels at a frame rate of 180,000 frames per second by the constructed parallel phase-shifting digital holography system. By applying the developed computer to the recorded holograms, we confirmed that the designed computer can accelerate the calculation of image-reconstruction process of parallel phase-shifting digital holography ~50 times faster than a CPU.

  17. Motion-compensated hand-held common-path Fourier-domain optical coherence tomography probe for image-guided intervention

    PubMed Central

    Huang, Yong; Liu, Xuan; Song, Cheol; Kang, Jin U.

    2012-01-01

    A motion-compensated, hand-held, common-path, Fourier-domain optical coherence tomography imaging probe has been developed for image-guided intervention during microsurgery. A hand-held prototype instrument was achieved by integrating an imaging fiber probe inside a stainless steel needle and attached to the ceramic shaft of a piezoelectric motor housed in an aluminum handle. The fiber probe obtains A-scan images. The distance information was extracted from the A-scans to track the sample surface distance and a fixed distance was maintained by a feedback motor control which effectively compensated hand tremor and target movements in the axial direction. Real-time data acquisition, processing, motion compensation, and image visualization and saving were implemented on a custom CPU-GPU hybrid architecture. We performed 10× zero padding to the raw spectrum to obtain 0.16 µm position accuracy with a compensation rate of 460 Hz. The root-mean-square error of hand-held distance variation from target position was measured to be 2.93 µm. We used a cross-correlation maximization-based shift correction algorithm for topology correction. To validate the system, we performed free-hand OCT M-scan imaging using various samples. PMID:23243562

  18. Motion-compensated hand-held common-path Fourier-domain optical coherence tomography probe for image-guided intervention.

    PubMed

    Huang, Yong; Liu, Xuan; Song, Cheol; Kang, Jin U

    2012-12-01

    A motion-compensated, hand-held, common-path, Fourier-domain optical coherence tomography imaging probe has been developed for image-guided intervention during microsurgery. A hand-held prototype instrument was achieved by integrating an imaging fiber probe inside a stainless steel needle and attached to the ceramic shaft of a piezoelectric motor housed in an aluminum handle. The fiber probe obtains A-scan images. The distance information was extracted from the A-scans to track the sample surface distance and a fixed distance was maintained by a feedback motor control which effectively compensated hand tremor and target movements in the axial direction. Real-time data acquisition, processing, motion compensation, and image visualization and saving were implemented on a custom CPU-GPU hybrid architecture. We performed 10× zero padding to the raw spectrum to obtain 0.16 µm position accuracy with a compensation rate of 460 Hz. The root-mean-square error of hand-held distance variation from target position was measured to be 2.93 µm. We used a cross-correlation maximization-based shift correction algorithm for topology correction. To validate the system, we performed free-hand OCT M-scan imaging using various samples. PMID:23243562

  19. Bessel Fourier Orientation Reconstruction (BFOR): An Analytical Diffusion Propagator Reconstruction for Hybrid Diffusion Imaging and Computation of q-Space Indices

    PubMed Central

    Hosseinbor, A. Pasha; Chung, Moo K.; Wu, Yu-Chien; Alexander, Andrew L.

    2012-01-01

    The ensemble average propagator (EAP) describes the 3D average diffusion process of water molecules, capturing both its radial and angular contents. The EAP can thus provide richer information about complex tissue microstructure properties than the orientation distribution function (ODF), an angular feature of the EAP. Recently, several analytical EAP reconstruction schemes for multiple q-shell acquisitions have been proposed, such as diffusion propagator imaging (DPI) and spherical polar Fourier imaging (SPFI). In this study, a new analytical EAP reconstruction method is proposed, called Bessel Fourier orientation reconstruction (BFOR), whose solution is based on heat equation estimation of the diffusion signal for each shell acquisition, and is validated on both synthetic and real datasets. A significant portion of the paper is dedicated to comparing BFOR, SPFI, and DPI using hybrid, non-Cartesian sampling for multiple b-value acquisitions. Ways to mitigate the effects of Gibbs ringing on EAP reconstruction are also explored. In addition to analytical EAP reconstruction, the aforementioned modeling bases can be used to obtain rotationally invariant q-space indices of potential clinical value, an avenue which has not yet been thoroughly explored. Three such measures are computed: zero-displacement probability (Po), mean squared displacement (MSD), and generalized fractional anisotropy (GFA). PMID:22963853

  20. Image fusion in x-ray differential phase-contrast imaging

    NASA Astrophysics Data System (ADS)

    Haas, W.; Polyanskaya, M.; Bayer, F.; Gödel, K.; Hofmann, H.; Rieger, J.; Ritter, A.; Weber, T.; Wucherer, L.; Durst, J.; Michel, T.; Anton, G.; Hornegger, J.

    2012-02-01

    Phase-contrast imaging is a novel modality in the field of medical X-ray imaging. The pioneer method is the grating-based interferometry which has no special requirements to the X-ray source and object size. Furthermore, it provides three different types of information of an investigated object simultaneously - absorption, differential phase-contrast and dark-field images. Differential phase-contrast and dark-field images represent a completely new information which has not yet been investigated and studied in context of medical imaging. In order to introduce phase-contrast imaging as a new modality into medical environment the resulting information about the object has to be correctly interpreted. The three output images reflect different properties of the same object the main challenge is to combine and visualize these data in such a way that it diminish the information explosion and reduce the complexity of its interpretation. This paper presents an intuitive image fusion approach which allows to operate with grating-based phase-contrast images. It combines information of the three different images and provides a single image. The approach is implemented in a fusion framework which is aimed to support physicians in study and analysis. The framework provides the user with an intuitive graphical user interface allowing to control the fusion process. The example given in this work shows the functionality of the proposed method and the great potential of phase-contrast imaging in medical practice.

  1. Overlapped Fourier coding for optical aberration removal

    PubMed Central

    Horstmeyer, Roarke; Ou, Xiaoze; Chung, Jaebum; Zheng, Guoan; Yang, Changhuei

    2014-01-01

    We present an imaging procedure that simultaneously optimizes a camera’s resolution and retrieves a sample’s phase over a sequence of snapshots. The technique, termed overlapped Fourier coding (OFC), first digitally pans a small aperture across a camera’s pupil plane with a spatial light modulator. At each aperture location, a unique image is acquired. The OFC algorithm then fuses these low-resolution images into a full-resolution estimate of the complex optical field incident upon the detector. Simultaneously, the algorithm utilizes redundancies within the acquired dataset to computationally estimate and remove unknown optical aberrations and system misalignments via simulated annealing. The result is an imaging system that can computationally overcome its optical imperfections to offer enhanced resolution, at the expense of taking multiple snapshots over time. PMID:25321982

  2. Assessment of material blending distribution for electrospun nanofiber membrane by Fourier transform infrared (FT-IR) microspectroscopy and image cluster analysis

    NASA Astrophysics Data System (ADS)

    Sunthornvarabhas, Jackapon; Thumanu, Kanjana; Limpirat, Wanwisa; Kim, Hyun-Joong; Piyachomkwan, Kuakoon; Sriroth, Klanarong

    2014-09-01

    Electrospun nanofibers between starch and polyethylene oxide were successfully prepared to be used as a template for wound healing application. Material blending ratios and fabrication conditions were optimized to determine the ability to control material spatial for further development. A fourier Transform Infrared (FT-IR) mapping system and purposed modified image clustering analysis were adopted to evaluate the material homogeneity of a sheet of homogeneous composite nanofibers. The fabrication conditions and material blending ratios both have an influence on the material distribution and optimum points were observed from this technique. This study showed the possibility of using a quick and non-destructive technique and a modified image cluster analysis technique to evaluate the homogeneity of the electrospun nanofiber sheet.

  3. Phase-sensitive X-ray imager

    DOEpatents

    Baker, Kevin Louis

    2013-01-08

    X-ray phase sensitive wave-front sensor techniques are detailed that are capable of measuring the entire two-dimensional x-ray electric field, both the amplitude and phase, with a single measurement. These Hartmann sensing and 2-D Shear interferometry wave-front sensors do not require a temporally coherent source and are therefore compatible with x-ray tubes and also with laser-produced or x-pinch x-ray sources.

  4. High-speed phase imaging by parallel phase-shifting digital holography.

    PubMed

    Kakue, Takashi; Yonesaka, Ryosuke; Tahara, Tatsuki; Awatsuji, Yasuhiro; Nishio, Kenzo; Ura, Shogo; Kubota, Toshihiro; Matoba, Osamu

    2011-11-01

    Parallel phase-shifting digital holography can obtain three-dimensional information of a dynamically moving object with high accuracy by using space-division multiplexing of multiple holograms required for phase-shifting interferometry. We demonstrated high-speed parallel phase-shifting digital holography and obtained images of the phase variation of air caused by a compressed gas flow sprayed from a nozzle. In particular, we found the interesting phenomenon of periodic phase distributions. Reconstructed images were obtained at frame rates of 20,000 and 180,000 frames per second. PMID:22048341

  5. To enhance imaging performance of hybrid imaging systems by using two asymmetrical phase masks.

    PubMed

    Le, Van Nhu; Chen, Shouqian; Fan, Zhigang; Pham, Nghia Minh

    2016-02-10

    We propose the use of two asymmetrical phase masks combined with the subtracted imaging method to enhance the signal-to-noise ratio in wavefront coding systems. This subtracted imaging technique is similar to the variable pinhole diameter in confocal microscopy. Two different phase modulations of same phase masks are employed to promote the magnitude of the optical transfer function (OTF). The ratio factor is used to control the phase variation between two phase masks. The noise of decoded images is suppressed owing to the higher magnitude of the OTF than the wavefront coding systems with a phase mask. A tangent phase mask as an example is used to demonstrate our concept. Simulated results show that the performance promotion controls noise amplification of decoded images while maintaining a depth-of-field extension. PMID:26906377

  6. Phase Sensitive X-Ray Imaging: Towards its Interdisciplinary Applications

    NASA Astrophysics Data System (ADS)

    Kottler, C.; Revol, V.; Kaufmann, R.; Urban, C.; Knop, K.; Sennhauser, U.; Jerjen, I.; Lüthi, T.; Cardot, F.; Niedermann, P.; Morel, J.-P.; Maake, C.; Walt, H.; Knop, E.; Blanc, N.

    2010-04-01

    X-ray phase imaging including phase tomography has been attracting increasing attention during the past few decades. The advantage of X-ray phase imaging is that an extremely high sensitivity is achieved for weakly absorbing materials, such as biological soft tissues, which generate a poor contrast by conventional schemes. Especially for such living samples, where the reduction of the applied dose is of paramount interest, phase sensitive measurements schemes have an inherent potential for a significant dose reduction combined with an image quality enhancement. Several methods have been invented for x-ray phase contrast imaging that either use an approach based on interferometry, diffraction or wave-field propagation. Some of these techniques have a potential for commercial applications, such as in medicine, non-destructive testing, security and inspection. The scope of this manuscript thus deals with one particular such technique that measures the diffraction caused by the specimen by means of a grating interferometer. Examples of measurements are shown that depict the potential of phase contrast imaging for future commercial applications, such as in medical imaging, non-destructive testing and inspection for quality control. The current state of the technology is briefly reviewed as well as its shortcomings to be overcome with regard to the applications.

  7. Transformation of light double cones in the human retina: the origin of trichromatism, of 4D-spatiotemporal vision, and of patchwise 4D Fourier transformation in Talbot imaging

    NASA Astrophysics Data System (ADS)

    Lauinger, Norbert

    1997-09-01

    The interpretation of the 'inverted' retina of primates as an 'optoretina' (a light cones transforming diffractive cellular 3D-phase grating) integrates the functional, structural, and oscillatory aspects of a cortical layer. It is therefore relevant to consider prenatal developments as a basis of the macro- and micro-geometry of the inner eye. This geometry becomes relevant for the postnatal trichromatic synchrony organization (TSO) as well as the adaptive levels of human vision. It is shown that the functional performances, the trichromatism in photopic vision, the monocular spatiotemporal 3D- and 4D-motion detection, as well as the Fourier optical image transformation with extraction of invariances all become possible. To transform light cones into reciprocal gratings especially the spectral phase conditions in the eikonal of the geometrical optical imaging before the retinal 3D-grating become relevant first, then in the von Laue resp. reciprocal von Laue equation for 3D-grating optics inside the grating and finally in the periodicity of Talbot-2/Fresnel-planes in the near-field behind the grating. It is becoming possible to technically realize -- at least in some specific aspects -- such a cortical optoretina sensor element with its typical hexagonal-concentric structure which leads to these visual functions.

  8. Phase estimation for magnetic resonance imaging near metal prostheses

    NASA Astrophysics Data System (ADS)

    Bones, Philip J.; King, Laura J.; Millane, Rick P.

    2015-09-01

    Magnetic resonance imaging (MRI) has the potential to be the best technique for assessing complications in patients with metal orthopedic implants. The presence of fat can obscure definition of the other soft tissues in MRI images, so fat suppression is often required. However, the performance of existing fat suppression techniques is inadequate near implants, due to very significant magnetic field perturbations induced by the metal. The three-point Dixon technique is potentially a method of choice as it is able to suppress fat in the presence of inhomogeneities, but the success of this technique depends on being able to accurately calculate the phase shift. This is generally done using phase unwrapping and/or iterative reconstruction algorithms. Most current phase unwrapping techniques assume that the phase function is slowly varying and phase differences between adjacent points are limited to less than π radians in magnitude. Much greater phase differences can be present near metal implants. We present our experience with two phase unwrapping techniques which have been adapted to use prior knowledge of the implant. The first method identifies phase discontinuities before recovering the phase along paths through the image. The second method employs a transform to find the least squares solution to the unwrapped phase. Simulation results indicate that the methods show promise.

  9. Motionless phase stepping in X-ray phase contrast imaging with a compact source.

    PubMed

    Miao, Houxun; Chen, Lei; Bennett, Eric E; Adamo, Nick M; Gomella, Andrew A; DeLuca, Alexa M; Patel, Ajay; Morgan, Nicole Y; Wen, Han

    2013-11-26

    X-ray phase contrast imaging offers a way to visualize the internal structures of an object without the need to deposit significant radiation, and thereby alleviate the main concern in X-ray diagnostic imaging procedures today. Grating-based differential phase contrast imaging techniques are compatible with compact X-ray sources, which is a key requirement for the majority of clinical X-ray modalities. However, these methods are substantially limited by the need for mechanical phase stepping. We describe an electromagnetic phase-stepping method that eliminates mechanical motion, thus removing the constraints in speed, accuracy, and flexibility. The method is broadly applicable to both projection and tomography imaging modes. The transition from mechanical to electromagnetic scanning should greatly facilitate the translation of X-ray phase contrast techniques into mainstream applications. PMID:24218599

  10. Motionless phase stepping in X-ray phase contrast imaging with a compact source

    PubMed Central

    Miao, Houxun; Chen, Lei; Bennett, Eric E.; Adamo, Nick M.; Gomella, Andrew A.; DeLuca, Alexa M.; Patel, Ajay; Morgan, Nicole Y.; Wen, Han

    2013-01-01

    X-ray phase contrast imaging offers a way to visualize the internal structures of an object without the need to deposit significant radiation, and thereby alleviate the main concern in X-ray diagnostic imaging procedures today. Grating-based differential phase contrast imaging techniques are compatible with compact X-ray sources, which is a key requirement for the majority of clinical X-ray modalities. However, these methods are substantially limited by the need for mechanical phase stepping. We describe an electromagnetic phase-stepping method that eliminates mechanical motion, thus removing the constraints in speed, accuracy, and flexibility. The method is broadly applicable to both projection and tomography imaging modes. The transition from mechanical to electromagnetic scanning should greatly facilitate the translation of X-ray phase contrast techniques into mainstream applications. PMID:24218599

  11. Phase 2 N01 Program - Cancer Imaging Program

    Cancer.gov

    The Phase 2 N01 Program is a CTEP-CIP collaboration includes 7 contractors, most of whom consist of multi-institutional consortia, and includes a total of 22 NCI-designated Cancer Centers. These sites carry out early clinical trials with CTEP and CIP-held IND agents, with an emphasis on phase 2 trials, but including phase 1 trials as well. These trials include the evaluation of novel imaging agents and methods to enhance the evaluation of novel therapeutics.

  12. Semiconductor defect metrology using laser-based quantitative phase imaging

    NASA Astrophysics Data System (ADS)

    Zhou, Renjie; Edwards, Chris; Popescu, Gabriel; Goddard, Lynford

    2015-03-01

    A highly sensitive laser-based quantitative phase imaging tool, using an epi-illumination diffraction phase microscope, has been developed for silicon wafer defect inspection. The first system used a 532 nm solid-state laser and detected 20 nm by 100 nm by 110 nm defects in a 22 nm node patterned silicon wafer. The second system, using a 405 nm diode laser, is more sensitive and has enabled detection of 15 nm by 90 nm by 35 nm defects in a 9 nm node densely patterned silicon wafer. In addition to imaging, wafer scanning and image-post processing are also crucial for defect detection.

  13. Triple-phase bone image abnormalities in Lyme arthritis

    SciTech Connect

    Brown, S.J.; Dadparvar, S.; Slizofski, W.J.; Glab, L.B.; Burger, M. )

    1989-10-01

    Arthritis is a frequent manifestation of Lyme disease. Limited triple-phase Tc-99m MDP bone imaging of the wrists and hands with delayed whole-body images was performed in a patient with Lyme arthritis. This demonstrated abnormal joint uptake in the wrists and hands in all three phases, with increased activity seen in other affected joints on delayed whole-body images. These findings are nonspecific and have been previously described in a variety of rheumatologic conditions, but not in Lyme disease. Lyme disease should be considered in the differential diagnosis of articular and periarticular bone scan abnormalities.

  14. Complex direct comb spectroscopy with a virtually imaged phased array.

    PubMed

    Scholten, Sarah K; Anstie, James D; Hébert, Nicolas Bourbeau; White, Richard T; Genest, Jérôme; Luiten, Andre N

    2016-03-15

    We demonstrate a simple interferometric technique to directly measure the complex optical transmittance over a large spectral range using a frequency-comb spectrometer based on a virtually imaged phased array. A Michelson interferometer encodes the phase deviations induced by a sample contained in one of its arms into an interferogram image. When combined with an additional image taken from each arm separately, along with a frequency-calibration image, this allows full reconstruction of the sample's optical transfer function. We demonstrate the technique with a vapor cell containing H13C14N, producing transmittance and phase spectra spanning 2.9 THz (∼23  nm) with ∼1  GHz resolution. PMID:26977688

  15. Spatially resolved homonuclear solid-state NMR. III. Magic-echo and rotary-echo phase-encoding imaging

    NASA Astrophysics Data System (ADS)

    Demco, D. E.; Hafner, S.; Kimm1ch, R.

    Two novel magic-echo pulse sequences are reported which are suitable for solid-state NMR imaging using the phase-encoding Fourier transform principle. With the magic- echo phase-encoding solid imaging (MEPSI) technique, ordinary gradients of the external magnetic field are employed. The rotary- echo phase-encoding solid imaging (REPSI) method, on the other hand, is based on gradients of the amplitude of the radiofrequency irradiated to the sample during the magic sandwich pulse in a certain analogy to rotating-frame zeugmatography. The use of magic echoes in solid-state NMR imaging experiments has two crucial advantages. The signal intensity in principle is recovered without incoherence losses. Second, the intervals during which the phase-encoding evolution takes place can be chosen much longer than with ordinary solid-echo experiments. Total encoding times in the order of milliseconds are feasible even with rigid solids. Thus the encoding efficiency of liquid-state imaging is approached. With given gradients, be they main field gradients in the case of MEPSI or gradients of the radiofrequency amplitude in the case of REPSI, therefore, a much better spatial resolution can be achieved than with other phase-encoding techniques. Theoretical treatments and test experiments are presented.

  16. Dual-wavelength digital holographic imaging with phase background subtraction

    NASA Astrophysics Data System (ADS)

    Khmaladze, Alexander; Matz, Rebecca L.; Jasensky, Joshua; Seeley, Emily; Holl, Mark M. Banaszak; Chen, Zhan

    2012-05-01

    Three-dimensional digital holographic microscopic phase imaging of objects that are thicker than the wavelength of the imaging light is ambiguous and results in phase wrapping. In recent years, several unwrapping methods that employed two or more wavelengths were introduced. These methods compare the phase information obtained from each of the wavelengths and extend the range of unambiguous height measurements. A straightforward dual-wavelength phase imaging method is presented which allows for a flexible tradeoff between the maximum height of the sample and the amount of noise the method can tolerate. For highly accurate phase measurements, phase unwrapping of objects with heights higher than the beat (synthetic) wavelength (i.e. the product of the original two wavelengths divided by their difference), can be achieved. Consequently, three-dimensional measurements of a wide variety of biological systems and microstructures become technically feasible. Additionally, an effective method of removing phase background curvature based on slowly varying polynomial fitting is proposed. This method allows accurate volume measurements of several small objects with the same image frame.

  17. Direct and simultaneous detection of organic and inorganic ingredients in herbal powder preparations by Fourier transform infrared microspectroscopic imaging.

    PubMed

    Chen, Jian-Bo; Sun, Su-Qin; Tang, Xu-Dong; Zhang, Jing-Zhao; Zhou, Qun

    2016-08-01

    Herbal powder preparation is a kind of widely-used herbal product in the form of powder mixture of herbal ingredients. Identification of herbal ingredients is the first and foremost step in assuring the quality, safety and efficacy of herbal powder preparations. In this research, Fourier transform infrared (FT-IR) microspectroscopic identification method is proposed for the direct and simultaneous recognition of multiple organic and inorganic ingredients in herbal powder preparations. First, the reference spectrum of characteristic particles of each herbal ingredient is assigned according to FT-IR results and other available information. Next, a statistical correlation threshold is determined as the lower limit of correlation coefficients between the reference spectrum and a larger number of calibration characteristic particles. After validation, the reference spectrum and correlation threshold can be used to identify herbal ingredient in mixture preparations. A herbal ingredient is supposed to be present if correlation coefficients between the reference spectrum and some sample particles are above the threshold. Using this method, all kinds of herbal materials in powder preparation Kouqiang Kuiyang San are identified successfully. This research shows the potential of FT-IR microspectroscopic identification method for the accurate and quick identification of ingredients in herbal powder preparations. PMID:27156099

  18. Fourier transform infrared imaging and microscopy studies of Pinus radiata pulps regarding the simultaneous saccharification and fermentation process.

    PubMed

    Castillo, Rosario del P; Araya, Juan; Troncoso, Eduardo; Vinet, Silenne; Freer, Juanita

    2015-03-25

    The distribution and chemical patterns of lignocellulosic components at microscopic scale and their effect on the simultaneous saccharification and fermentation process (SSF) in the production of bioethanol from Pinus radiata pulps were analyzed by the application of diverse microscopical techniques, including scanning electronic microscopy (SEM), confocal laser scanning microscopy (CLSM) and attenuated total reflectance (ATR) - Fourier transform infrared microspectroscopy. This last technique was accompanied with multivariate methods, including principal component analysis (PCA) and multivariate curve resolution with alternating least squares (MCR-ALS) to evaluate the distribution patterns and to generate pure spectra of the lignocellulosic components of fibers. The results indicate that the information obtained by the techniques is complementary (ultrastructure, confocality and chemical characterization) and that the distribution of components affects the SSF yield, identifying lignin coalescence droplets as a characteristic factor to increase the SSF yield. Therefore, multivariate analysis of the infrared spectra enabled the in situ identification of the cellulose, lignin and lignin-carbohydrates arrangements. These techniques could be used to investigate the lignocellulosic components distribution and consequently their recalcitrance in many applications where minimal sample manipulation and microscale chemical information is required. PMID:25732688

  19. Direct, object brightness estimation from atmospheric turbulence degraded images using a new high-speed, modified phase diversity method

    NASA Astrophysics Data System (ADS)

    Arrasmith, William W.

    2008-04-01

    The well known phase diversity technique has long been used as a premier passive imaging method to mitigate the degrading effects of atmospheric turbulence on incoherent optical imagery. Typically, an iterative, slow method is applied that uses the Zernike basis set and 2-D Fourier transforms in the reconstruction process. In this paper, we demonstrate a direct method for estimating the un-aberrated object brightness from phase or phase difference estimates that 1) does not require the use of the Zernike basis set or the intermediate determination of the generalized pupil function, 2) directly determines the optical transfer function without the requirement for an iterative sequence of 2-D Fourier Transforms, 3) provides a more accurate result than the Zernike-based approaches since there are no Zernike series truncation errors, 4) lends itself to fast and parallel implementation, and 5) can use stochastic search methods to rapidly determine simultaneous phases or phase differences required to determine the correct optical transfer function estimate. As such, this new implementation of phase diversity provides potentially faster, more accurate results than previous approaches yet still retains inherent compatibility with the traditional Zernike-based methods. The theoretical underpinnings of this new method along with demonstrative computer simulation results are presented.

  20. Cell-sensitive phase contrast microscopy imaging by multiple exposures.

    PubMed

    Yin, Zhaozheng; Su, Hang; Ker, Elmer; Li, Mingzhong; Li, Haohan

    2015-10-01

    We propose a novel way of imaging live cells in a Petri dish by the phase contrast microscope. By taking multiple exposures of phase contrast microscopy images on the same cell dish, we estimate a cell-sensitive camera response function which responds to cells' irradiance signals but generates a constant on non-cell background signal. The result of this new microscopy imaging is visually superior quality, which reveals the appearance details of cells and suppresses background noise near zero. Using the cell-sensitive microscopy imaging, cells' original irradiance signals are restored from all exposures and the irradiance signals on non-cell background regions are restored as a uniform constant (i.e., the imaging system is sensitive to cells only but insensitive to non-cell background). The restored irradiance signals greatly facilitate the cell segmentation by simple thresholding. The experimental results validate that high quality cell segmentation can be achieved by our approach. PMID:25977155