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1

Cord blood full blood count parameters in Lagos, Nigeria  

PubMed Central

Introduction Full blood count (FBC), one of the most frequently requested for laboratory investigations, is a simple, fast and cheap test and is a reliable indicator of health. Due to its usefulness in the assessment of health status of individuals, its parameters in cord blood, a major source of haemopoietic stem cell transplantation and an ideal source for laboratory investigations for newborns were determined to provide a useful guide to local neonatologists and stem cell transplant physicians. Methods Three millilitres of umbilical cord blood was collected from 130 normal birth weight newborns (69 males and 61 females) whose cord were clamped immediately after delivery, at a teaching hospital in Lagos, Nigeria and full blood count parameters were determined using Sysmex autoanalyzer, model KX-21N. Consented mothers of the newborns were selected based on, age between 18 and 45 years; uneventful pregnancy and delivery and haemoglobin (Hb) concentration ? 10 g/dL. Results There were no statistical gender differences in the mean values of Hb concentrations (M = 13.27 ±1.60 g/dL; F = 13.32±1.61g/dL; p = 0.93), total white cell count (M = 3.16±5.43 × 109/L; F = 13.07±4.98 × 109/L; p= 0.92), platelet count (M= 223.64± 64.21 × 109/L; F = 226.69±80.83 × 109/L; p = 0.81) and other parameters. Conclusion Mean values of full blood count parameters obtained in this study are comparable to reports from other studies in developing countries and could be a useful guide for neonatologists and stem cell transplant physicians in our geographical location. PMID:25396018

Adewumi, Adediran; Titilope A, Adeyemo; Akinsegun, Akinbami A; Abidoye, Gbadegesin; Ebele, Uche; Sulaimon, Akanmu A

2014-01-01

2

Interpretation of the full blood count in systemic disease--a guide for the physician.  

PubMed

The full blood count (FBC) is perhaps the single most common investigation performed in medical patients. It has the potential, when interpreted carefully and in relation to the clinical history, to provide very useful information to assist in diagnosis and management. Clinicians are often alerted to the presence of a primary haematological disorder by abnormalities in the FBC. For the purpose of this review these diseases will not be discussed in detail but the reader will be alerted to pointers which might indicate primary blood disorders throughout the text. The haematology laboratory in large teaching hospitals will often provide up to 1,500 automated FBC analyses each day. These are individually checked for 'flags' provided by the analyser which indicate values outside the normal range. It is clearly essential that clinical information is provided with the request as this will influence how the result is handled by scientific and medical staff. Furthermore, significant abnormalities will generate a blood film request and the report will be most useful when interpreted in light of the patient's working diagnosis. In cases where a diagnosis is not yet known, even brief information on presentation, for example 'collapse with hypotension', 'fever on return to UK', 'weight loss and anorexia', can all be important and help the lab provide clinicians with guidance. This short review aims to provide physicians with a workable guide to the interpretation of some of the commoner findings in the full blood count. Some of these will be very familiar to you but some will not. This review is not meant to be exhaustive as the rare minutiae will obscure the essential core material. Your haematology colleagues are always happy to help and available for assistance in difficult or problematic cases. I have not specified normal ranges in relation to each entity as these will be defined by your local laboratory. PMID:24995446

Leach, M

2014-01-01

3

The use of the white cell count and haemoglobin in combination as an effective screen to predict the normality of the full blood count  

PubMed Central

Introduction The utility of the full blood count (FBC) is vast with each parameter serving as a tool to aid diagnosis and monitor disease progression. However, the effectiveness of the test is hampered because of increased workload and lack of interpretation. In the effort to redress this issue, the combined use of the white blood cell count (WBC) and haemoglobin in predicting the normality of the FBC is evaluated. Method FBC data were collated from 2191 patients and classified into two groups depending on whether the WBC and the haemoglobin were within the reference range. Blood films were examined on the abnormal FBC samples in each group and graded on morphology. Results The FBC was normal in 89.6% of cases in the presence of a normal WBC and haemoglobin with subtle abnormalities in the remainder; 1+ grading of abnormal morphology in 93%. However, when the WBC and/or haemoglobin was abnormal, the remaining FBC was significantly abnormal (P < 0.05) and the corresponding blood films were grossly abnormal; 2+/3+ grading in 96% of cases. Conclusion We concluded that in the presence of a normal WBC and haemoglobin, the FBC is normal in almost all cases and measuring these two parameters could be used as an effective screen to predict FBC normality. PMID:21883968

OSEI-BIMPONG, A; McLEAN, R; BHONDA, E; LEWIS, S M

2012-01-01

4

White blood cell count - series (image)  

MedlinePLUS

The White Blood Cell (WBC) Count measures two components: the total number of WBC's (leukocytes), and the differential count. ... and basophils) and non-granulocytes (lymphocytes and monocytes). White blood cells are a major component of the ...

5

Full counting statistics of Luttinger liquid conductor  

Microsoft Academic Search

Non-equilibrium bosonization technique is used to study current fluctuations\\u000aof interacting electrons in a single-channel quantum wire representing a\\u000aLuttinger liquid (LL) conductor. An exact expression for the full counting\\u000astatistics of the transmitted charge is derived. It is given by Fredholm\\u000adeterminant of the counting operator with a time dependent scattering phase.\\u000aThe result has a form of counting

D. B. Gutman; Yuval Gefen; A. D. Mirlin

2010-01-01

6

Complete Blood Count (CBC) Interpretation  

NSDL National Science Digital Library

This tutorial is designed to aid first and second year medical students learn how to interpret a complete blood count. It includes material on how the test is done, its general application and pitfalls in interpretation. QuickTime movies and Java script runtime plug-in scripts are required for some pages. The tutorial concludes with a short self-help quiz covering the major points developed. The plug-ins noted above are available free at the following sites: http://www.apple.com/quicktime/download/win.html and http://www.sun.com/. Questions should be directed to Dr. Mark Braun (braunm@indiana.edu).Annotated: false

2010-05-31

7

Complete blood count - series (image)  

MedlinePLUS

... hematocrit may indicate: Dehydration Burns Diarrhea Eclampsia Erythrocytosis Polycythemia vera Shock ... blood Congenital heart disease Cor pulmonale Pulmonary fibrosis Polycythemia vera Dehydration (such as from severe diarrhea) Emphysema

8

Counting microaggregate particles in blood.  

PubMed

A method is described for measuring microaggregates in stored blood with an electronic particle counter avoiding the usual use of a hemolytic agent. To overcome red blood cell coincidence at low dilutions of the samples two different sized apertures were used. The method reliably measures microaggregates from 12.7 micron to 80.6 micron diameter. Hemolytic agents added to fresh blood were shown to induce the formation of microaggregates. The present study demonstrated that a tenfold reduction in a commonly used saponin concentration produced satisfactory hemolysis without inducing significant microaggregate formation. Hemolytic agents added to stored blood decreased the population of microaggregates significantly from that of unhemolyzed blood. This phenomenon was minimized with reduced saponin concentrations. PMID:663994

Suehiro, A; Leinberger, H; McNamara, J J

1978-01-01

9

Blood leucocyte count in the human fetus  

Microsoft Academic Search

Total and differential leucocyte counts were measured in cord blood samples obtained by cordocentesis (n = 316) or at elective caesarean section (n = 11) from normal fetuses of between 18 and 40 weeks' gestation. The total fetal leucocyte count increased exponentially from 2.8 x 10(9)\\/l at 18 weeks to 11.8 x 10(9)\\/l at term. The lymphocyte and monocyte counts

N P Davies; A G Buggins; R J Snijders; E Jenkins; D M Layton; K H Nicolaides

1992-01-01

10

21 CFR 864.6160 - Manual blood cell counting device.  

Code of Federal Regulations, 2010 CFR

... 2010-04-01 false Manual blood cell counting device. 864.6160 Section...Hematology Devices § 864.6160 Manual blood cell counting device. (a) Identification. A manual blood cell counting device is a device used to...

2010-04-01

11

Why Count Types of White Blood Cells?  

NSDL National Science Digital Library

How can we make use of complex cellular level responses in the human body to microbial infections and other disorders? Why is it important to differentiate between white blood cells in a blood sample and keep a record of their numbers? Improve skills at cell identification and explore these questions with the program Cell Differentials. * identify lymphocytes in a clinical laboratory simulation of blood cell counts

Ethel D. Stanley (Beloit College;Biology); Donald Buckley (Quinnipiac University;Biology)

2006-05-20

12

Homeostatic regulation of blood neutrophil counts  

PubMed Central

Neutrophil counts in blood are determined by the differentiation and proliferation of precursor cells in the bone marrow, release of mature neutrophils into the blood, margination in organs like the lung and spleen, and transmigration through the endothelial lining followed by neutrophil apoptosis and uptake by phagocytes. This brief review summarizes how the regulation of neutrophil production by G-CSF is in part controlled by IL-17 and IL-23. Neutrophils are retained in the bone marrow through interaction of CXCL12 with its receptor CXCR4. The relevance of this mechanism is illustrated by rare diseases in which disrupting the desensitization of CXCR4 results in neutrophil accumulation in the bone marrow. Although blood neutrophil numbers in inbred mouse strains and individual human subjects are tightly controlled, the large variation of blood neutrophil counts among outbred populations suggests genetic control. One example is benign ethnic neutropenia, which is found in about 5% of African Americans. Reduced and elevated neutrophil counts, even within the normal range, are associated with excess all-cause mortality. PMID:18832668

von Vietinghoff, Sibylle; Ley, Klaus

2009-01-01

13

Full counting statistics of persistent current  

NASA Astrophysics Data System (ADS)

We develop a method for the calculation of charge-transfer statistics of persistent current in nanostructures in terms of the cumulant generating function (CGF) of transferred charge. We consider a simply connected one-dimensional system (a wire) and develop a procedure for the calculation of the CGF of persistent currents when the wire is closed into a ring via a weak link. For the noninteracting system we derive a general formula in terms of the two-particle Green's functions. We show that, contrary to the conventional tunneling contacts, the resulting cumulant generating function has a doubled periodicity as a function of the counting field. We apply our general formula to short tight-binding chains and show that the resulting CGF perfectly reproduces the known evidence for the persistent current. Its second cumulant turns out to be maximal at the switching points and vanishes identically at zero temperature. Furthermore, we apply our formalism for a computation of the charge-transfer statistics of genuinely interacting systems. First we consider a ring with an embedded Anderson impurity and employing a self-energy approximation find an overall suppression of persistent current as well as of its noise. Finally, we compute the charge-transfer statistics of a double-quantum-dot system in the deep Kondo limit using an exact analytical solution of the model at the Toulouse point. We analyze the behavior of the resulting cumulants and compare them with those of a noninteracting double-quantum-dot system and find several pronounced differences, which can be traced back to interaction effects.

Komnik, A.; Langhanke, G. W.

2014-10-01

14

Full Counting Statistics of a Luttinger Liquid Conductor  

Microsoft Academic Search

Nonequilibrium bosonization technique is used to study current fluctuations of interacting electrons in a single-channel quantum wire representing a Luttinger liquid (LL) conductor. An exact expression for the time resolved full counting statistics of the transmitted charge is derived. It is given by the Fredholm determinant of the counting operator with a time-dependent scattering phase. The result has a form

D. B. Gutman; Yuval Gefen; A. D. Mirlin

2010-01-01

15

Full counting statistics of a Luttinger liquid conductor.  

PubMed

Nonequilibrium bosonization technique is used to study current fluctuations of interacting electrons in a single-channel quantum wire representing a Luttinger liquid (LL) conductor. An exact expression for the time resolved full counting statistics of the transmitted charge is derived. It is given by the Fredholm determinant of the counting operator with a time-dependent scattering phase. The result has a form of counting statistics of noninteracting particles with fractional charges, induced by scattering off the boundaries between the LL wire and the noninteracting leads. PMID:21231608

Gutman, D B; Gefen, Yuval; Mirlin, A D

2010-12-17

16

Full counting statistics of chaotic cavities from classical action correlations  

E-print Network

We present a trajectory-based semiclassical calculation of the full counting statistics of quantum transport through chaotic cavities, in the regime of many open channels. Our method to obtain the $m$th moment of the density of transmission eigenvalues requires two correlated sets of $m$ classical trajectories, therefore generalizing previous works on conductance and shot noise. The semiclassical results agree, for all values of $m$, with the corresponding predictions from random matrix theory.

G. Berkolaiko; J. M. Harrison; M. Novaes

2007-03-30

17

21 CFR 864.6160 - Manual blood cell counting device.  

... FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES HEMATOLOGY AND PATHOLOGY DEVICES Manual Hematology Devices § 864.6160 Manual blood cell counting device. (a) Identification. A...

2014-04-01

18

21 CFR 864.6160 - Manual blood cell counting device.  

Code of Federal Regulations, 2011 CFR

... FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES HEMATOLOGY AND PATHOLOGY DEVICES Manual Hematology Devices § 864.6160 Manual blood cell counting device. (a) Identification. A...

2011-04-01

19

21 CFR 864.6160 - Manual blood cell counting device.  

Code of Federal Regulations, 2012 CFR

... FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES HEMATOLOGY AND PATHOLOGY DEVICES Manual Hematology Devices § 864.6160 Manual blood cell counting device. (a) Identification. A...

2012-04-01

20

21 CFR 864.6160 - Manual blood cell counting device.  

Code of Federal Regulations, 2013 CFR

... FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES HEMATOLOGY AND PATHOLOGY DEVICES Manual Hematology Devices § 864.6160 Manual blood cell counting device. (a) Identification. A...

2013-04-01

21

Prognostic Value of Elevated White Blood Cell Count in Hypertension  

Microsoft Academic Search

Background: Chronic low-grade inflammation may contribute to vascular injury and atherogenesis, and has been described in association to high blood pressure (BP). However, as yet the prognostic significance of white blood cell (WBC) count in the setting of uncomplicated hypertension has not been investigated.Methods: In the Progetto Ipertensione Umbria Monitoraggio Ambulatoriale (PIUMA) study, 1617 white patients with essential hypertension (aged

Giuseppe Schillaci; Matteo Pirro; Giacomo Pucci; Tiziana Ronti; Gaetano Vaudo; Massimo R. Mannarino; Carlo Porcellati; Elmo Mannarino

2007-01-01

22

Pediatric metabolic syndrome and cell blood counts: bivariate Bayesian modeling.  

PubMed

Cell blood counts are components of hematological parameters and indicators of pro-inflammatory states. They are proposed to be associated with metabolic syndrome (MetS). This study aimed to assess the relationship of the white blood cell (WBC) and the red blood cell (RBC) counts with components of MetS in the pediatric age group. The sample consisted of 300 children (152 boys) aged 6-12 years. Hierarchical Bayesian analysis of the bivariate Poisson regression model was used to estimate the effect of various components of MetS according to the cell blood counts. We found that RBC and WBC counts were correlated with the fasting blood glucose, the waist-to-height ratio, serum triglycerides and the blood pressure levels adjusted for age, the body mass index, gender, total cholesterol, low-density lipoprotein cholesterol and the hip circumference. The high-density lipoprotein cholesterol was correlated with the RBC counts based on 95% high posterior density regions for parameters in the Bayesian model. Our findings may serve as confirmatory evidence for the beginning of inflammatory process related to the cardio-metabolic factors from early life. PMID:24108065

Mansourian, Marjan; Kazemi, Iraj; Kelishadi, Roya

2014-02-01

23

Yield of the admission complete blood count in medical inpatients.  

PubMed Central

The clinical efficacy of routine admission complete blood count was evaluated in 302 patients admitted to internal medicine wards of a university teaching hospital. Patient medical problems, physical findings and medication history were evaluated by preset criteria to determine the proportion of tests performed for screening and the proportion of test results directly influencing patient management. Of the 282 complete blood counts performed, 80% were ordered routinely with no medical indications (screening tests). An haemoglobin abnormality was found in 16.7% of the patients, leucocyte abnormality in 16.1% and platelet abnormality in 4.6%. However, these results directly influenced patient management in only one case (0.14%). It is concluded that the utility of screening admission complete blood counts in medical inpatients is negligible. PMID:2602251

Mozes, B.; Haimi-Cohen, Y.; Halkin, H.

1989-01-01

24

A system for counting fetal and maternal red blood cells.  

PubMed

The Kleihauer-Betke (KB) test is the standard method for quantitating fetal-maternal hemorrhage in maternal care. In hospitals, the KB test is performed by a certified technologist to count a minimum of 2000 fetal and maternal red blood cells (RBCs) on a blood smear. Manual counting suffers from inherent inconsistency and unreliability. This paper describes a system for automated counting and distinguishing fetal and maternal RBCs on clinical KB slides. A custom-adapted hardware platform is used for KB slide scanning and image capturing. Spatial-color pixel classification with spectral clustering is proposed to separate overlapping cells. Optimal clustering number and total cell number are obtained through maximizing cluster validity index. To accurately identify fetal RBCs from maternal RBCs, multiple features including cell size, roundness, gradient, and saturation difference between cell and whole slide are used in supervised learning to generate feature vectors, to tackle cell color, shape, and contrast variations across clinical KB slides. The results show that the automated system is capable of completing the counting of over 60 000 cells (versus  ? 2000 by technologists) within 5 min (versus  ? 15 min by technologists). The throughput is improved by approximately 90 times compared to manual reading by technologists. The counting results are highly accurate and correlate strongly with those from benchmarking flow cytometry measurement. PMID:24879644

Ge, Ji; Gong, Zheng; Chen, Jun; Liu, Jun; Nguyen, John; Yang, Zongyi; Wang, Chen; Sun, Yu

2014-12-01

25

Full counting statistics of quantum dot resonance fluorescence  

PubMed Central

The electronic energy levels and optical transitions of a semiconductor quantum dot are subject to dynamics within the solid-state environment. In particular, fluctuating electric fields due to nearby charge traps or other quantum dots shift the transition frequencies via the Stark effect. The environment dynamics are mapped directly onto the fluorescence under resonant excitation and diminish the prospects of quantum dots as sources of indistinguishable photons in optical quantum computing. Here, we present an analysis of resonance fluorescence fluctuations based on photon counting statistics which captures the underlying time-averaged electric field fluctuations of the local environment. The measurement protocol avoids dynamic feedback on the electric environment and the dynamics of the quantum dot's nuclear spin bath by virtue of its resonant nature and by keeping experimental control parameters such as excitation frequency and external fields constant throughout. The method introduced here is experimentally undemanding. PMID:24810097

Matthiesen, Clemens; Stanley, Megan J.; Hugues, Maxime; Clarke, Edmund; Atature, Mete

2014-01-01

26

Absolute counting of neutrophils in whole blood using flow cytometry.  

PubMed

Absolute neutrophil count (ANC) is used clinically to monitor physiological dysfunctions such as myelosuppression or infection. In the research laboratory, ANC is a valuable measure to monitor the evolution of a wide range of disease states in disease models. Flow cytometry (FCM) is a fast, widely used approach to confidently identify thousands of cells within minutes. FCM can be optimised for absolute counting using spiked-in beads or by measuring the sample volume analysed. Here we combine the 1A8 antibody, specific for the mouse granulocyte protein Ly6G, with flow cytometric counting in straightforward FCM assays for mouse ANC, easily implementable in the research laboratory. Volumetric and Trucount™ bead assays were optimized for mouse neutrophils, and ANC values obtained with these protocols were compared to ANC measured by a dual-platform assay using the Orphee Mythic 18 veterinary haematology analyser. The single platform assays were more precise with decreased intra-assay variability compared with ANC obtained using the dual protocol. Defining ANC based on Ly6G expression produces a 15% higher estimate than the dual protocol. Allowing for this difference in ANC definition, the flow cytometry counting assays using Ly6G can be used reliably in the research laboratory to quantify mouse ANC from a small volume of blood. We demonstrate the utility of the volumetric protocol in a time-course study of chemotherapy induced neutropenia using four drug regimens. © 2014 International Society for Advancement of Cytometry. PMID:24995861

Brunck, Marion E G; Andersen, Stacey B; Timmins, Nicholas E; Osborne, Geoffrey W; Nielsen, Lars K

2014-12-01

27

Counting  

NSDL National Science Digital Library

Practicing Counting Count the number of bunnies and match it to the correct number of characters on the right. Click on the correct one. Bunny Count Practice counting by 1 Countin by 1 Practice counting Sea Horses! Counting Sea Horses ...

Person, Ms.

2007-11-28

28

Single-use lancet and capillary loading mechanism for complete blood count point of care device  

E-print Network

As part of the development of a point of care complete blood count device, I designed a single use lancet integrated with a blood collection mechanism and interface and successfully tested a prototype. High speed video was ...

Zimmerman, Julia C

2011-01-01

29

Comparison between a modified haemocytometric technique and electronic counters in goat blood cell counting.  

PubMed

Dilutions of goat blood with Hayem-Jørgensen's fluid ranging from 1:200 to 1:1,000 were used for haemocytometer counting of red blood cells (RBC) in 27 goats. The optimal dilutions were 1:400-1:500. Correlation studies between the results obtained by the haemocytometer and the Coulter counter red blood cell (RBC) and white blood cell (WBC) counts were performed in 551 goat blood samples. The haemocytometer RBC counts were 5.63% higher and WBC counts 2.79% lower than those of the electronic counter. The method of blood cell counting therefore influences the clinical haematological diagnoses and reference values in domestic animals. New cell counters specifically designed to measure cells of small volumes, e.g. goat erythrocytes, are needed. PMID:1910237

Mbassa, G K; Poulsen, J S

1991-06-01

30

Counting  

NSDL National Science Digital Library

Students will practice counting different objects. Have fun counting with this counting game. Play the game three times. Go under the sea with Fishy Count. Play the game three times. These spooky ghosts want you to practice counting by 2 s. ...

Beck, Mrs.

2006-12-08

31

Lower white blood cell counts in elite athletes training for highly aerobic sports  

Microsoft Academic Search

White cell counts at rest might be lower in athletes participating in selected endurance-type sports. Here, we analysed blood\\u000a tests of elite athletes collected over a 10-year period. Reference ranges were established for 14 female and 14 male sports\\u000a involving 3,679 samples from 937 females and 4,654 samples from 1,310 males. Total white blood cell counts and counts of neutrophils,

P. L. Horn; D. B. Pyne; W. G. Hopkins; C. J. Barnes

2010-01-01

32

Automated counting of white blood cells in synovial fluid  

Microsoft Academic Search

Results. The WBC count of the DIFF channel was highly correlated with the WBC count of the microscopic reference method (r ¼ 0.99; WBC analyser ¼ 0.870 ? WBC reference method þ 0.413). In contrast, no agreement existed between WBC counts generated by the WBC\\/BASO channel of the analyser and the reference method (r ¼ 0.52; WBC analyser ¼ 0.008

R. de Jonge; R. Brouwer; M. Smit; R. J. E. M. Dolhain; J. M. W. Hazes; A. W. van Toorenenbergen; J. Lindemans

2003-01-01

33

Pseudospontaneous Platelet Aggregation and Spuriously Elevated Blood Cell Counts in Cryoglobulinemia  

Microsoft Academic Search

Cryoglobulinemia has been reported sometimes to cause false elevation in platelet and\\/or leukocyte counts in au tomated blood cell counters due to temperature-dependent pro tein precipitates that are falsely interpreted as blood cells at room temperature. Upon heating to 37°C, these blood counts decrease to normal levels as cryoproteins dissolve. Therefore, cryoglobulins could theoretically lead to erroneous diagnosis of spontaneous

Yahya Büyüka?ik; N. ?emnur ileri; Ibrahim C. Haznedaroglu; Selma Karaahmetoglu; Osman Müftüo?lu; ?erafettin Kirazli; Semra Dündar

1998-01-01

34

CELL TYPES, DIFFERENTIAL CELL COUNTS, AND BLOOD CELL MEASUREMENTS OF  

E-print Network

count than those repolted for other sharks. 10 Microns I I FIGURE I.-Mitosis-Prophase. Cell Differentials FIGURE 2.-Mitosis-Anaphase. The mean size of the POltuguese shark mature erythrocytes (Figure 3

35

Dynamic changes in white blood cell counts in uncomplicated Plasmodium falciparum and P. vivax malaria  

Microsoft Academic Search

Total and differential white blood cell (WBC) counts are basic and essential indicators in any type of illness resulting from infection. In malaria, WBC counts are generally characterized as low to normal during treatment. WBC-counts data, before and during treatment with artemisinin derivatives, was gathered for patients with either Plasmodium falciparum or Plasmodium vivax infection (at 28-day follow-up), to investigate

Noppadon Tangpukdee; Haur-Sen Yew; Srivicha Krudsood; Nataya Punyapradit; Waraporn Somwong; Sornchai Looareesuwan; Shigeyuki Kano; Polrat Wilairatana

2008-01-01

36

Full counting statistics and phase diagram of a dissipative Rydberg gas.  

PubMed

Ultracold gases excited to strongly interacting Rydberg states are a promising system for quantum simulations of many-body systems. For off-resonant excitation of such systems in the dissipative regime, highly correlated many-body states exhibiting, among other characteristics, intermittency and multimodal counting distributions are expected to be created. Here we report on the realization of a dissipative gas of rubidium Rydberg atoms and on the measurement of its full counting statistics and phase diagram for both resonant and off-resonant excitation. We find strongly bimodal counting distributions in the off-resonant regime that are compatible with intermittency due to the coexistence of dynamical phases. Our results pave the way towards detailed studies of many-body effects in Rydberg gases. PMID:25062177

Malossi, N; Valado, M M; Scotto, S; Huillery, P; Pillet, P; Ciampini, D; Arimondo, E; Morsch, O

2014-07-11

37

Nucleated Red Blood Cells Count in Pregnancies with Idiopathic Intra-Uterine Growth Restriction  

PubMed Central

Objective Elevated nucleated red blood cell (NRBC) count is introduced as a potential marker of intra-uterine growth restriction (IUGR). To investigate the probable association regardless of any known underlying disease, we aimed to study disturbances in NRBC count in infants experiencing idiopathic IUGR. Materials and methods Twenty three infants regarded IUGR without any known cause were chosen to be compared to 48 normal neonates. Blood samples were collected instantly after birth and the same measurements were done in both groups. Results NRBC count/100 white blood cells was significantly higher in the IUGR group (P value < 0.001). pH measurements did not reveal any significant difference. Conclusion Increased NRBC count in cases of idiopathic IUGR in absence of chronic hypoxia could strengthen its predictive value suggested in previous studies. It could help early IUGR detection and beneficial intervention. PMID:24971139

Kaveh, Mahbod; Nemati, Somayeh; Javadian, Pouya; Salmanian, Bahram

2014-01-01

38

Characterizing correlations with full counting statistics: classical Ising and quantum XY spin chains.  

PubMed

We propose to describe correlations in classical and quantum systems in terms of full counting statistics of a suitably chosen discrete observable. The method is illustrated with two exactly solvable examples: the classical one-dimensional Ising model and the quantum spin-1/2 XY chain. For the one-dimensional Ising model, our method results in a phase diagram with two phases distinguishable by the long-distance behavior of the Jordan-Wigner strings. For the anisotropic spin-1/2 XY chain in a transverse magnetic field, we compute the full counting statistics of the magnetization and use it to classify quantum phases of the chain. The method, in this case, reproduces the previously known phase diagram. We also discuss the relation between our approach and the Lee-Yang theory of zeros of the partition function. PMID:23496467

Ivanov, Dmitri A; Abanov, Alexander G

2013-02-01

39

Full dynamics of a red blood cell in shear flow  

PubMed Central

At the cellular scale, blood fluidity and mass transport depend on the dynamics of red blood cells in blood flow, specifically on their deformation and orientation. These dynamics are governed by cellular rheological properties, such as internal viscosity and cytoskeleton elasticity. In diseases in which cell rheology is altered genetically or by parasitic invasion or by changes in the microenvironment, blood flow may be severely impaired. The nonlinear interplay between cell rheology and flow may generate complex dynamics, which remain largely unexplored experimentally. Under simple shear flow, only two motions, “tumbling” and “tank-treading,” have been described experimentally and relate to cell mechanics. Here, we elucidate the full dynamics of red blood cells in shear flow by coupling two videomicroscopy approaches providing multidirectional pictures of cells, and we analyze the mechanical origin of the observed dynamics. We show that contrary to common belief, when red blood cells flip into the flow, their orientation is determined by the shear rate. We discuss the “rolling” motion, similar to a rolling wheel. This motion, which permits the cells to avoid energetically costly deformations, is a true signature of the cytoskeleton elasticity. We highlight a hysteresis cycle and two transient dynamics driven by the shear rate: an intermittent regime during the “tank-treading-to-flipping” transition and a Frisbee-like “spinning” regime during the “rolling-to-tank-treading” transition. Finally, we reveal that the biconcave red cell shape is highly stable under moderate shear stresses, and we interpret this result in terms of stress-free shape and elastic buckling. PMID:23213229

Dupire, Jules; Socol, Marius; Viallat, Annie

2012-01-01

40

Neonatal nucleated red blood cell counts in growth-restricted fetuses: Relationship to arterial and venous Doppler studies  

Microsoft Academic Search

Objective: Elevated nucleated red blood cell count in neonatal blood and Doppler-detected circulatory decompensation in fetuses with intrauterine growth restriction are associated with hypoxemia. We sought to determine the relationship between the nucleated red blood cell count at birth and the circulatory status of fetuses with intrauterine growth restriction. Study Design: Eighty-four fetuses with elevated umbilical artery pulsatility index values

Ahmet A. Baschat; Ulrich Gembruch; Irwin Reiss; Ludwig Gortner; Chris R. Harman; Carl P. Weiner

1999-01-01

41

WBC count  

MedlinePLUS

Leukocyte count; White blood cell count ... in the blood is 4,500-10,000 white blood cells per microliter (mcL). Normal value ranges ... LOW WHITE BLOOD CELL (WBC) COUNT A low number of WBCs is called leukopenia. A WBC count below 4500 ...

42

Lindblad equation approach for the full counting statistics of work and heat in driven quantum systems  

E-print Network

We formulate the general approach based on the Lindblad equation to calculate the full counting statistics of work and heat produced by driven quantum systems weakly coupled with a Markovian thermal bath. The approach can be applied to a wide class of dissipative quantum systems driven by an arbitrary force protocol. We show the validity of general fluctuation relations and consider several generic examples. The possibilities of using calorimetric measurements to test the presence of coherence and entanglement in the open quantum systems are discussed.

Mihail Silaev; Tero T. Heikkilä; Pauli Virtanen

2013-12-12

43

Equation of motion method for Full Counting Statistics: Steady state superradiance  

E-print Network

For the multi-mode Dicke model in a transport setting that exhibits collective boson transmissions, we construct the equation of motion for the cumulant generating function. Approximating the exact system of equations at the level of cumulant generating function and system operators at lowest order, allows us to recover master equation results of the Full Counting Statistics for certain parameter regimes at very low cost of computation. The thermodynamic limit, that is not accessible with the master equation approach, can be derived analytically for different approximations.

Malte Vogl; Gernot Schaller; Eckehard Schöll; Tobias Brandes

2012-06-19

44

Small and cheap: accurate differential blood count with minimal sample volume by laser scanning cytometry (LSC)  

NASA Astrophysics Data System (ADS)

Aim: In patients, e.g. with congenital heart diseases, a differential blood count is needed for diagnosis. To this end by standard automatic analyzers 500 ?l of blood is required from the patients. In case of newborns and infants this is a substantial volume, especially after operations associated with blood loss. Therefore, aim of this study was to develop a method to determine a differential blood picture with a substantially reduced specimen volume. Methods: To generate a differential blood picture 10 ?l EDTA blood were mixed with 10 ?l of a DRAQ5 solution (500?M, Biostatus) and 10 ?l of an antibody mixture (CD45-FITC, CD14-PE, diluted with PBS). 20 ?l of this cell suspension was filled into a Neubauer counting chamber. Due to the defined volume of the chamber it is possible to determine the cell count per volume. The trigger for leukocyte counting was set on DRAQ5 signal in order to be able to distinguish nucleated white blood cells from erythrocytes. Different leukocyte subsets could be distinguished due to the used fluorescence labeled antibodies. For erythrocyte counting cell suspension was diluted another 150 times. 20 ?l of this dilution was analyzed in a microchamber by LSC with trigger set on forward scatter signal. Results: This method allows a substantial decrease of blood sample volume for generation of a differential blood picture (10 ?l instead of 500?l). There was a high correlation between our method and the results of routine laboratory (r2=0.96, p<0.0001 n=40). For all parameters intra-assay variance was less than 7 %. Conclusions: In patients with low blood volume such as neonates and in critically ill infants every effort has to be taken to reduce the blood volume needed for diagnostics. With this method only 2% of standard sample volume is needed to generate a differential blood picture. Costs are below that of routine laboratory. We suggest this method to be established in paediatric cardiology for routine diagnostics and for resource poor settings.

Mittag, Anja; Lenz, Dominik; Smith, Paul J.; Pach, Susanne; Tarnok, Attila

2005-04-01

45

Blood cell counting in neonates: a comparison between a low volume micromethod and the standard laboratory method  

PubMed Central

Background Iatrogenic anaemia caused by repeated blood sampling to monitor laboratory parameters can contribute, particularly in neonates, to the need for transfusion. “Point of care” laboratory equipment uses smaller amounts of blood for analytic determinations and could, therefore, help to prevent secondary anaemia. In this study we compared the results of haematological parameters measured using a standard laboratory method and using a “point of care” micromethod, with the aim of validating the use of this latter method in clinical practice in neonatology. Materials and methods One hundred and fifty venous or capillary blood samples were taken from full-term or premature neonates 2–4 hours or 48 hours after birth. Each sample was processed by a standard haematology analyser and another micromethod instrument. Bland-Altman plots were constructed for each parameter and intra-class coefficients of correlation were calculated in order to evaluate the concordance between the two analysers. Results The concordance between the data obtained with the two analysers, expressed as the intra-class correlation, was 0.98 for white blood cell count, 0.97 for haemoglobin concentration, 0.96 for haematocrit, 0.95 for mean red cell volume and 0.98 for platelet count. The micromethod produced overestimated mean values for the leucocyte count (+1.27; p<0.001), haematocrit (+1.80; p<0.001) and platelet count (+13.55; p<0.001). Conclusions Overall, the concordance between the values obtained with the two analysers was high for each of the parameters taken into consideration. In the case of haemoglobin and leucocytes, give the high intra-class correlation and lack of systematic overestimation of one method over another, the micromethod guarantees a correct evaluation; however, despite the high intra-class correlations for platelet counts, the systemic error seems to suggest that the micromethod cannot guarantee an appropriate evaluation of this parameter. PMID:21839016

Papa, Fabrizio; Rongioletti, Mauro; Ventura, Marco Della; Di Turi, Francesco; Cortesi, Maurizio; Pasqualetti, Patrizio; Majolini, Maria Bernardetta; Collegiani, Valeria; Cicchese, Marika; Notarmuzi, Maria Letizia; Agostino, Rocco; Liumbruno, Giancarlo Maria

2011-01-01

46

Lower white blood cell counts in elite athletes training for highly aerobic sports.  

PubMed

White cell counts at rest might be lower in athletes participating in selected endurance-type sports. Here, we analysed blood tests of elite athletes collected over a 10-year period. Reference ranges were established for 14 female and 14 male sports involving 3,679 samples from 937 females and 4,654 samples from 1,310 males. Total white blood cell counts and counts of neutrophils, lymphocytes and monocytes were quantified. Each sport was scaled (1-5) for its perceived metabolic stress (aerobic-anaerobic) and mechanical stress (concentric-eccentric) by 13 sports physiologists. Substantially lower total white cell and neutrophil counts were observed in aerobic sports of cycling and triathlon (~16% of test results below the normal reference range) compared with team or skill-based sports such as water polo, cricket and volleyball. Mechanical stress of sports had less effect on the distribution of cell counts. The lower white cell counts in athletes in aerobic sports probably represent an adaptive response, not underlying pathology. PMID:20640439

Horn, P L; Pyne, D B; Hopkins, W G; Barnes, C J

2010-11-01

47

Blood counts at time of complete remission provide additional independent prognostic information in acute myeloid leukemia  

PubMed Central

Prognostic relevance of blood counts at complete remission (CR) in acute myeloid leukemia (AML) is not clear. To address this issue, we analyzed 891 AML patients in first CR. From the data of randomly selected 446 patients (training set), we first established optimal cutoffs for neutrophil and platelet counts and hemoglobin level at CR in terms of relapse-free survival (RFS). Patients whose counts were higher than each optimal cutoff were shown to have significantly better RFS (p < 0.01 for neutrophil and platelets, and p = 0.02 for hemoglobin). Then we tested whether these cutoffs were, after accounting for better known prognostic covariates, also predictive of RFS in the remaining 445 patients (validation set). Our data revealed that higher neutrophil count was independently predictive of longer RFS in the validation set (hazard ratio 1.38, p = 0.02), as was higher platelet count (hazard ratio 1.35, p = 0.04). These findings suggest that blood counts at CR, information readily available, are useful in prognostication in AML. PMID:18405972

Yanada, Masamitsu; Borthakur, Gautam; Garcia-Manero, Guillermo; Ravandi, Farhad; Faderl, Stefan; Pierce, Sherry; Kantarjian, Hagop; Estey, Elihu

2014-01-01

48

A rapid method for counting nucleated erythrocytes on stained blood smears by digital image analysis  

USGS Publications Warehouse

Measures of parasitemia by intraerythrocytic hematozoan parasites are normally expressed as the number of infected erythrocytes per n erythrocytes and are notoriously tedious and time consuming to measure. We describe a protocol for generating rapid counts of nucleated erythrocytes from digital micrographs of thin blood smears that can be used to estimate intensity of hematozoan infections in nonmammalian vertebrate hosts. This method takes advantage of the bold contrast and relatively uniform size and morphology of erythrocyte nuclei on Giemsa-stained blood smears and uses ImageJ, a java-based image analysis program developed at the U.S. National Institutes of Health and available on the internet, to recognize and count these nuclei. This technique makes feasible rapid and accurate counts of total erythrocytes in large numbers of microscope fields, which can be used in the calculation of peripheral parasitemias in low-intensity infections.

Gering, E.; Atkinson, C.T.

2004-01-01

49

The blood counts and lactate dehydrogenase levels in thrombotic thrombocytopenic purpura (TTP).  

PubMed

The blood counts and lactic dehydrogenase values of eight patients with thrombotic thrombocytopenic purpura (TTP) were reviewed in relation to the clinical course. Three of the eight patients died. In these patients, the hemoglobin was significantly lower and the LDH higher at the time of presentation than that of the patients responding to treatment. The height of the absolute reticulocyte count and platelet count did not correlate as well with outcome as did the degree of anemia and LDH elevation. Microangiopathic changes were noted in all eight patients. A differential count showed that the total microangiopathic changes varied from 0.8 to 54%. The more severe microangiopathic changes occurred in the fatal cases. The observations indicate that the degree of anemia, elevation of LDH, and severity of microangiopathic changes at the time of presentation correlate with the outcome in TTP and provide useful parameters in the assessment of response to therapy. PMID:6685430

Crowley, J P; Metzger, J B; L'Europa, R A

1983-11-01

50

Complete blood cell count in psittaciformes by using high-throughput image cytometry: a pilot study.  

PubMed

The avian hemogram is usually performed in veterinary diagnostic laboratories by using manual cell counting techniques and differential counts determined by light microscopy. There is no standard automated technique for avian blood cell count and differentiation to date. These shortcomings in birds are primarily because erythrocytes and thrombocytes are nucleated, which precludes the use of automated analyzers programmed to perform mammal complete blood cell counts. In addition, there is no standard avian antibody panel, which would allow cell differentiation by immunophenotyping across all commonly seen bird species. We report an alternative hematologic approach for quantification and differentiation of avian blood cells by using high-throughput image cytometry on blood smears in psittacine bird species. A pilot study was designed with 70 blood smears of different psittacine bird species stained with a Wright-Giemsa stain. The slides were scanned at 0.23 microm/pixel. The open-source softwares CellProfiler and CellProfiler Analyst were used for analyzing and sorting each cell by image cytometry. A "pipeline" was constructed in the CellProfiler by using different modules to identify and export hundreds of measures per cell for shape, intensity, and texture. Rules for classifying the different blood cell phenotypes were then determined based on these measurements by iterative feedback and machine learning by using CellProfiler Analyst. Although this approach shows promises, avian Leukopet results could not be duplicated when using this technique as is. Further studies and more standardized prospective investigations may be needed to refine the "pipeline" strategy and the machine learning algorithm. PMID:24344512

Beaufrère, Hugues; Ammersbach, Mélanie; Tully, Thomas N

2013-09-01

51

Trajectory phase transitions, Lee-Yang zeros, and high-order cumulants in full counting statistics.  

PubMed

We investigate Lee-Yang zeros of generating functions of dynamical observables and establish a general relation between phase transitions in ensembles of trajectories of stochastic many-body systems and the time evolution of high-order cumulants of such observables. This connects dynamical free energies for full counting statistics in the long-time limit, which can be obtained via large-deviation methods and whose singularities indicate dynamical phase transitions, to observables that are directly accessible in simulation and experiment. As an illustration, we consider facilitated spin models of glasses and show that from the short-time behavior of high-order cumulants, it is possible to infer the existence and location of dynamical or "space-time" transitions in these systems. PMID:23414009

Flindt, Christian; Garrahan, Juan P

2013-02-01

52

White blood cell differential counts in severely leukopenic samples: a comparative analysis of different solutions available in modern laboratory hematology  

PubMed Central

Background We evaluated the efficacy of white blood cell (WBC) differential counts in severely leukopenic samples by the Hematoflow method and by automated hematology analyzers and compared the results with manual counts. Methods EDTA-anticoagulated blood samples (175 samples) with WBC counts of 40-990/µL were selected. Hematoflow differential counts were performed in duplicates employing flow cytometry using the CytoDiff reagent and analysis software. Differential counts were also performed using the DxH 800 (Beckman Coulter) and XE-2100 (Sysmex) automated hematology analyzers. The sum of the manual counts by a hematology technician and a resident were used as the manual counts. Results The total analysis time and hands-on time required by the Hematoflow method were shorter than those required by manual counting. Hematoflow counts were reproducible, showed a good correlation with automated analyzers, and also showed strong correlation with manual counts (r > 0.8) in neutrophils, lymphocytes, and monocytes. None of the cases containing less than 4% blasts as analyzed by the Hematoflow method had blasts in the manual counts, but 8 cases of 21 cases (38.1%) with over 4% blasts by Hematoflow had blasts in manual counts. Conclusion Hematoflow counts of severely leukopenic samples were reproducible and showed a good correlation with manual counts in terms of neutrophil, lymphocyte, and monocyte counts. The Hematoflow method also detected the presence of blasts. Manual slide review is recommended when over 4% blasts are found by Hematoflow. PMID:25025014

Kim, Ah Hyun; Lee, Wonbae; Kim, Myungshin; Kim, Yonggoo

2014-01-01

53

Physical activity, white blood cell count, and lung cancer risk in a prospective cohort study  

PubMed Central

Previous studies have suggested that physical activity may lower lung cancer risk. The association of physical activity with reduced chronic inflammation provides a potential mechanism, yet few studies have directly related inflammatory markers to cancer incidence. The relation between physical activity, inflammation, and lung cancer risk was evaluated in a prospective cohort of 4,831 subjects, 43–86 years of age, in Beaver Dam, Wisconsin. A total physical activity index was created by summing kilocalories per week from sweat-inducing physical activities, city blocks walked, and flights of stairs climbed. Two inflammatory markers, white blood cell count and serum albumin, were measured at the baseline examination. During an average of 12.8 years of follow-up, 134 incident cases of lung cancer were diagnosed. After multivariable adjustment, participants in the highest tertile of total physical activity index had a 45% reduction in lung cancer risk compared to those in the lowest tertile (OR=0.55; 95% CI: 0.35–0.86). Participants with white blood cell counts in the upper tertile (?8×103/?L) were 2.81 (95% CI: 1.58–5.01) times as likely to develop lung cancer as those with counts in the lowest tertile (<6.4×103/?L). Serum albumin was not related to lung cancer risk. There was no evidence that inflammation mediated the association between physical activity and lung cancer risk, as the physical activity risk estimates were essentially unchanged after adjustment for white blood cell count. While the potential for residual confounding by smoking could not be eliminated, these data suggest that physical activity and white blood cell count are independent risk factors for lung cancer. PMID:18843014

Sprague, Brian L.; Trentham-Dietz, Amy; Klein, Barbara E.K.; Klein, Ronald; Cruickshanks, Karen J.; Lee, Kristine E.; Hampton, John M.

2009-01-01

54

Diagnostic significance of platelet count and other blood analyses in patients with lung cancer.  

PubMed

The objective of this study was to evaluate the clinical value of an elevated platelet count and other routine laboratory tests for predicting malignancy in patients with radiologically suspected lung cancer. Platelet count, haemoglobin, total leukocyte count, erythrocyte sedimentation rate (ESR) and serum lactate dehydrogenase (LDH) were analysed in 126 prospectively admitted patients with suspected lung cancer. The patients were divided by pathologic diagnosis into those with benign disorders (n=65) and with malignancies (n=61). Patients with lung cancer were staged (TNM) and the tumours were classified according to histological types (WHO). Thrombocytosis (platelet count >400x10(9)/l) was present in 8% (5/65) of patients with benign disease and in 57% (35/61) of patients with malignant disease (p<0.00001). The prevalence of thrombocytosis in patients with primary lung cancer was 53% (27/51). Elevated platelet count was more common in advanced disease (stage III and IV). No difference was observed between histological types. The sensitivity of thrombocytosis for predicting malignancy was 0.57 and the specificity 0.92. When elevated platelet counts, LDH and ESR were combined, a sensitivity of 0.71 and a specificity of 1.00 was achieved. The positive and negative predictive values were 1.00 and 0.89, respectively. Elevated platelet count is frequently observed in patients with lung cancer. When test results of platelet count and other routine blood analyses are combined, a high sensitivity and specificity for predicting malignancy can be achieved. These tests are clinically useful in the evaluation of patients with radiologically suspected lung cancer. PMID:12469171

Pedersen, Lars M; Milman, Nils

2003-01-01

55

A comparative study of white blood cell counts and disease risk in carnivores.  

PubMed Central

In primates, baseline levels of white blood cell (WBC) counts are related to mating promiscuity. It was hypothesized that differences in the primate immune system reflect pathogen risks from sexually transmitted diseases (STDs). Here, we test for the generality of this result by examining hypotheses involving behavioural, ecological and life-history factors in carnivores. Again, we find a significant correlation in carnivores between mating promiscuity and elevated levels of WBC counts. In addition, we find relationships with measures of sociality, substrate use and life-history parameters. These comparative results across independent taxonomic orders indicate that the evolution of the immune system, as represented by phylogenetic differences in basal levels of blood cell counts, is closely linked to disease risk involved with promiscuous mating and associated variables. We found only limited support for an association between the percentage of meat in the diet and WBC counts, which is consistent with the behavioural and physiological mechanisms that carnivores use to avoid parasite transmission from their prey. We discuss additional comparative questions related to taxonomic differences in disease risk, modes of parasite transmission and implications for conservation biology. PMID:12639313

Nunn, Charles L; Gittleman, John L; Antonovics, Janis

2003-01-01

56

Quantization and fractional quantization of currents in periodically driven stochastic systems. II. Full counting statistics.  

PubMed

We study Markovian stochastic motion on a graph with finite number of nodes and adiabatically periodically driven transition rates. We show that, under general conditions, the quantized currents that appear at low temperatures are a manifestation of topological invariants in the counting statistics of currents. This observation provides an approach for classification of topological properties of the counting statistics, as well as for extensions of the phenomenon of the robust quantization of currents at low temperatures to the properties of the counting statistics which persist to finite temperatures. PMID:22519316

Chernyak, Vladimir Y; Klein, John R; Sinitsyn, Nikolai A

2012-04-21

57

Telomere Length in Elderly Caucasians Weakly Correlates with Blood Cell Counts  

PubMed Central

Background. Age-related decrease in bone marrow erythropoietic capacity is often accompanied by the telomere length shortening in peripheral white blood cells. However, limited and conflicting data hamper the conclusive opinion regarding this relationship. Therefore, the aim of this study was to assess an association between telomere length and peripheral blood cell count parameters in the Polish elderly population. Material and Methods. The substudy included 1573 of 4981 subjects aged 65 years or over, participants of the population-based PolSenior study. High-molecular-weight DNA was isolated from blood mononuclear cells. Telomere length (TL) was measured by QRT-PCR as abundance of telomere template versus a single gene copy encoding acidic ribosomal phosphoprotein P0. Results. Only white blood count (WBC) was significantly different in TL tertile subgroups in all subjects (P = 0.02) and in men (P = 0.01), but not in women. Merely in men significant but weak positive correlations were found between TL and WBC (r = 0.11, P < 0.05) and RBC (r = 0.08, P < 0.05). The multiple regression analysis models confirmed a weak, independent contribution of TL to both RBC and WBC. Conclusions. In the elderly, telomere shortening limits hematopoiesis capacity to a very limited extent. PMID:24453794

Witecka, Joanna; Koscinska-Marczewska, Justyna; Szwed, Malgorzata; Owczarz, Magdalena; Mossakowska, Malgorzata; Milewicz, Andrzej; Zejda, Jan; Wiecek, Andrzej

2013-01-01

58

Which observations from the complete blood cell count predict mortality for hospitalized patients?  

PubMed Central

Background Information on the prognostic utility of the admission complete blood count (CBC) and differential count is lacking. Objective To identify independent predictors of mortality from the varied number and morphology of cells in the complete blood count defined as a hemogram, automated five cell differential count and manual differential count. Design Retrospective cohort study and chart review. Setting Wishard Memorial Hospital, a large urban primary care hospital. Patients 46,522 adult inpatients admitted over ten years to Wishard Memorial Hospital from January 1993 through December of 2002. Intervention None Measurements 30-day mortality measured from day of admission as determined by electronic medical records and Indiana State Death records. Results Controlling for age and gender, the multivariable regression model identified three strong independent predictors of 30-day mortality: Presence of nucleated RBCs, burr cells, or absolute lymphocytosis was associated with a three-fold increased risk of mortality at 30 days. Nucleated RBCs were associated with a 25.5% 30-day mortality rate across a range of diagnoses, excluding sickle cell disease and obstetrical patients in which NRBCs were not associated with increased mortality. Burr cells were associated with a 27.3% mortality rate and found most commonly in patients with renal failure or liver failure. Absolute lymphocytosis predicted a poor outcome in trauma and CNS injury patients. Conclusions In patients admitted to the hospital, presence of nucleated RBCs, burr cells, or absolute lymphocytosis at admission is each associated with a three-fold increase in risk of 30-day mortality. PMID:17274042

Kho, Abel N; Hui, Siu; Kesterson, Joe G.; McDonald, Clement J

2013-01-01

59

Improved particle identification using cluster counting in a full-length drift chamber prototype  

NASA Astrophysics Data System (ADS)

Single-cell prototype drift chambers were built at TRIUMF and tested with a ~210 MeV/c beam of positrons, muons, and pions. A cluster-counting technique is implemented which improves the ability to distinguish muons and pions when combined with a traditional truncated-mean charge measurement. Several cluster-counting algorithms and equipment variations are tested, all showing significant improvement when combined with the traditional method. The results show that cluster counting is a feasible option for any particle physics experiment using drift chambers for particle identification. The technique does not require electronics with an overly high sampling rate. Optimal results are found with a signal smoothing time of ~5 ns corresponding to a ~100 MHz Nyquist frequency.

Caron, Jean-François; Hearty, Christopher; Lu, Philip; So, Rocky; Cheaib, Racha; Martin, Jean-Pierre; Faszer, Wayne; Beaulieu, Alexandre; de Jong, Samuel; Roney, Michael; de Sangro, Riccardo; Felici, Giulietto; Finocchiaro, Giuseppe; Piccolo, Marcello

2014-01-01

60

Improved Particle Identification Using Cluster Counting in a Full-Length Drift Chamber Prototype  

E-print Network

Single-cell prototype drift chambers were built at TRIUMF and tested with a $\\sim\\unit[210]{MeV/c}$ beam of positrons, muons, and pions. A cluster-counting technique is implemented which improves the ability to distinguish muons and pions when combined with a traditional truncated-mean charge measurement. Several cluster-counting algorithms and equipment variations are tested, all showing significant improvement when combined with the traditional method. The results show that cluster counting is a feasible option for any particle physics experiment using drift chambers for particle identification. The technique does not require electronics with an overly high sampling rate. Optimal results are found with a signal smoothing time of $\\sim\\unit[5]{ns}$ corresponding to a $\\sim\\unit[100]{MHz}$ Nyquist frequency.

Caron, Jean-François; Lu, Philip; So, Rocky; Cheaib, Racha; Martin, Jean-Pierre; Faszer, Wayne; Beaulieu, Alexandre; de Jong, Samuel; Roney, Michael; de Sangro, Riccardo; Felici, Giulietto; Finocchiaro, Giuseppe; Piccolo, Marcello

2014-01-01

61

Blood Neutrophil Counts in HIV-Infected Patients with Pulmonary Tuberculosis: Association with Sputum Mycobacterial Load  

PubMed Central

Background Increasing evidence suggests that neutrophils play a role in the host response to Mycobacterium tuberculosis. We determined whether neutrophil counts in peripheral blood are associated with tuberculosis (TB) and with mycobacterial load in sputum in HIV-infected patients. Methodology/Principal Findings Adults enrolling in an antiretroviral treatment (ART) clinic in a Cape Town township were screened for TB regardless of symptoms. Paired sputum samples were examined using liquid culture, fluorescence microscopy, and the Xpert MTB/RIF assay. Absolute neutrophil counts (ANC) were measured in blood samples. Of 602 HIV-infected patients screened, 523 produced one or more sputum samples and had complete results available for analysis. Among these 523 patients, the median CD4 count was 169×109/L (IQR, 96–232) and median ANC was 2.6×109/L (IQR, 1.9–3.6). Culture-positive pulmonary tuberculosis was diagnosed in 89 patients. Patients with TB had a median ANC of 3.4×109/L (IQR, 2.4–5.1) compared to 2.5×109/L (IQR, 1.8–3.4) among those who were culture negative (p<0.0001). In multivariable analyses, having pulmonary TB was associated with an adjusted risk ratio (aRR) of 2.6 (95%CI, 1.5–4.5) for having an ANC level that exceeded the median value (ANC ?2.6×109/L; p?=?0.0006) and an aRR of 6.8 (95%CI, 2.3–20.4) for having neutrophilia defined by a neutrophil count exceeding the upper limit of the normal range (ANC >7.5×109/L; p?=?0.0005). Patients were then classified into four mutually exclusive groups with increasing sputum mycobacterial load as defined by the results of culture, Xpert MTB/RIF and sputum smear microscopy. Multivariable analyses demonstrated that increasing sputum mycobacterial load was positively associated with blood ANC ?2.6×109/L and with neutrophilia. Conclusions/Significance Increased blood neutrophil counts were independently associated with pulmonary TB and sputum mycobacterial burden in this HIV-infected patient group. This observation supports the growing body of literature regarding the potential role for neutrophils in the host response to TB. PMID:23874476

Kerkhoff, Andrew D.; Wood, Robin; Lowe, David M.; Vogt, Monica; Lawn, Stephen D.

2013-01-01

62

A Multiple Parameters Biodosimetry Tool with Various Blood Cell Counts - the Hemodose Approach  

NASA Technical Reports Server (NTRS)

There continue to be important concerns about the possibility of the occurrence of acute radiation syndromes following nuclear and radiological terrorism or accidents that may result in mass casualties in densely populated areas. To guide medical personnel in their clinical decisions for effective medical management and treatment of the exposed individuals, biological markers are usually applied to examine radiation induced biological changes to assess the severity of radiation injury to sensitive organ systems. Among these the peripheral blood cell counts are widely used to assess the extent of radiation induced bone marrow injury. This is due to the fact that the hematopoietic system is the most vulnerable part of the human body to radiation damage. Particularly, the lymphocyte, granulocyte, and platelet cells are the most radiosensitive of the blood elements, and monitoring their changes after exposure is regarded as a practical and recommended laboratory test to estimate radiation dose and injury. Based upon years of physiological and pathophysiological investigation of mammalian hematopoietic systems, and rigorous coarse-grained bio-mathematical modeling and validation on species from mouse, to dog, monkey, and human, we have developed a set of software tools Hemodose, which can use single or serial granulocyte, lymphocyte, leukocyte, or platelet counts after exposure to estimate absorbed doses of adult victims very rapidly and accurately. Some patient data from historical accidents are utilized as examples to demonstrate the capabilities of these tools as a rapid point-of-care diagnostic or centralized high-throughput assay system in a large-scale radiological disaster scenario. Most significant to the improvement of national and local preparedness of a potential nuclear/radiological disaster, this HemoDose approach establishes robust correlations between the absorbed doses and victim's various types of blood cell counts not only in the early time window (1 or 2 days), but also in the very late phase (up to 4 weeks) after exposure.

Hu, Shaowen

2014-01-01

63

Correlation of Circulating MMP-9 with White Blood Cell Count in Humans: Effect of Smoking  

PubMed Central

Background Matrix metalloproteinase-9 (MMP-9) is an emerging biomarker for several disease conditions, where white blood cell (WBC) count is also elevated. In this study, we examined the relationship between MMP-9 and WBC levels in apparently healthy smoking and non-smoking human subjects. Methods We conducted a cross-sectional study to assess the relationship of serum MMP-9 with WBC in 383 men and 356 women. Next, we divided the male population (women do not smoke in this population) into three groups: never (n?=?243), current (n?=?76) and former (n?=?64) smokers and compared the group differences in MMP-9 and WBC levels and their correlations within each group. Results Circulating MMP-9 and WBC count are significantly correlated in men (R2?=?0.13, p<0.001) and women (R2?=?0.19, p<0.001). After stratification by smoking status, MMP-9 level was significantly higher in current smokers (mean ± SE; 663.3±43.4 ng/ml), compared to never (529.7±20.6) and former smokers (568±39.3). WBC count was changed in a similar pattern. Meanwhile, the relationship became stronger in current smokers with increased correlation coefficient of r?=?0.45 or R2?=?0.21 (p<0.001) and steeper slope of ß?=?1.16±0.30 (p<0.001) in current smokers, compared to r?=?0.26 or R2?=?0.07 (p<0.001) and ß?=?0.34±0.10 (p<0.001) in never smokers. Conclusions WBC count accounts for 13% and 19% of MMP-9 variance in men and women, respectively. In non-smoking men, WBC count accounts for 7% of MMP-9 variance, but in smoking subjects, it accounts for up to 21% of MMP-9 variance. Thus, we have discovered a previously unrecognized correlation between the circulating MMP-9 and WBC levels in humans. PMID:23825535

Ryan, Kathleen A.; Yu, Daozhan; Shuldiner, Alan R.; Mitchell, Braxton D.; Gong, Da-Wei

2013-01-01

64

White blood cell count and mortality in patients with acute pulmonary embolism.  

PubMed

Although associated with adverse outcomes in other cardiovascular diseases, the prognostic value of an elevated white blood cell (WBC) count, a marker of inflammation and hypercoagulability, is uncertain in patients with pulmonary embolism (PE). We therefore sought to assess the prognostic impact of the WBC in a large, state-wide retrospective cohort of patients with PE. We evaluated 14,228 patient discharges with a primary diagnosis of PE from 186 hospitals in Pennsylvania. We used random-intercept logistic regression to assess the independent association between WBC count levels at the time of presentation and mortality and hospital readmission within 30 days, adjusting for patient and hospital characteristics. Patients with an admission WBC count <5.0, 5.0-7.8, 7.9-9.8, 9.9-12.6, and >12.6 × 10(9) /L had a cumulative 30-day mortality of 10.9%, 6.2%, 5.4%, 8.3%, and 16.3% (P < 0.001), and a readmission rate of 17.6%, 11.9%, 10.9%, 11.5%, and 15.0%, respectively (P < 0.001). Compared with patients with a WBC count 7.9-9.8 × 10(9) /L, adjusted odds of 30-day mortality were significantly greater for patients with a WBC count <5.0 × 10(9) /L (odds ratio [OR] 1.52, 95% confidence interval [CI] 1.14-2.03), 9.9-12.6 × 10(9) /L (OR 1.55, 95% CI 1.26-1.91), or >12.6 × 10(9) /L (OR 2.22, 95% CI 1.83-2.69), respectively. The adjusted odds of readmission were also significantly increased for patients with a WBC count <5.0 × 10(9) /L (OR 1.34, 95% CI 1.07-1.68) or >12.6 × 10(9) /L (OR 1.29, 95% CI 1.10-1.51). In patients presenting with PE, WBC count is an independent predictor of short-term mortality and hospital readmission. PMID:23674436

Venetz, Carmen; Labarère, José; Jiménez, David; Aujesky, Drahomir

2013-08-01

65

Full range determination of ²²²Rn at the watershed scale by liquid scintillation counting.  

PubMed

(222)Rn has been increasingly used to identify groundwater contribution to surface water. Particular attention has been paid to analytical protocols and counting parameters used for liquid alpha scintillation measurements over a range of activities covering river and groundwater domains. Direct measurements and Rn-extraction protocols are optimized, and scintillometer efficiency is calibrated using international standards over the 0.5-35 Bq/L range. The interval of activities was performed in surface water and groundwater from a small Canadian watershed. PMID:23466700

Lefebvre, K; Barbecot, F; Ghaleb, B; Larocque, M; Gagné, S

2013-05-01

66

Full counting statistics in disordered graphene at the Dirac point: From ballistics to diffusion A. Schuessler,1  

E-print Network

Full counting statistics in disordered graphene at the Dirac point: From ballistics to diffusion A analytically both on ballistic and diffusive sides. In the ballistic regime, we use a diagrammatic technique and noise in ballistic graphene flakes.9­11 Recent advances in preparation and transport stud- ies

Fominov, Yakov

67

Acute effects of second-hand smoke on complete blood count.  

PubMed

We assessed the acute effects of a 1-h exposure to second-hand smoke (SHS) on complete blood count (CBC) markers in a controlled simulated bar/restaurant environment. Nineteen adult never-smokers completed a 1-h .exposure to SHS at bar/restaurant levels, and a 1-h exposure to normal room air. Blood samples were collected at the baseline at 30?min during each exposure, and at 0, 0.5, 1, 2, 3, and 4?h after each exposure. The values of white blood cells (WBC) at 1?h (p?=?0.010), 3?h (p?=?0.040), and 4?h (p?=?0.008) following SHS were significantly increased compared with the baseline values. Also, there was a positive association between the WBC and cotinine levels (r?=?0.28, p?=?0.007). A 1-h exposure to SHS at bar/restaurant levels significantly increased the WBC for at least 4?h following the exposure time. This effect of SHS on WBC has dose-response characteristics and should be considered to prescribing CBC. PMID:23544435

Dinas, Petros C; Metsios, Giorgos S; Jamurtas, Athanasios Z; Tzatzarakis, Manolis N; Wallace Hayes, A; Koutedakis, Yiannis; Tsatsakis, Aristidis M; Flouris, Andreas D

2014-01-01

68

Automated white blood cell counts in cerebrospinal fluid using the body fluid mode on the platform Sysmex XE-5000.  

PubMed

Abstract Background. The Sysmex XE-5000 offers automated quantification of red blood cells and white blood cells (WBCs) in body fluids, with differentiation of polymorphonuclear cells (PMNs) and mononuclear cells (MNCs). Methods. We evaluated automated WBC counting in cerebrospinal fluid (CSF) using the body fluid mode on the Sysmex XE-5000, comparing it with flow cytometry as the reference method, and also with manual counting by microscopy. Experimental analysis for linearity and limit of detection was performed by diluting isolated WBCs in cell-free CSF. To study the ability to discriminate between PMNs and MNCs, samples were spiked using MNCs separated from peripheral blood. Comparison of WBC counts between a counting chamber and the XE-5000 was performed for 198 CSF samples. Results. In the experimental set-up, within-run (CV 19%) and between-day imprecision (CV 15.3%) in quantitating total number of WBC on XE-5000 was acceptable for WBC counts ? 25 × 10(6)/L. Compared with expected cell counts, mean bias was + 2.6% for flow cytometry, + 5.5% for XE-5000 and - 73.2% for manual counting. Differentiation between PMNs and MNCs was in concordance with flow cytometry. In comparisons of clinical CSF samples, overall agreement between the XE-5000 and manual counting was observed in 81% of the samples, but mean difference in WBC differentiation was higher for PMN (51.1 × 10(6)/L) than for MNC (7.95 × 10(6)/L). Conclusion. Despite limited precision at low WBC counts, XE-5000 could be a favourable alternative to the labour-intensive, time-consuming and less reliable manual counting and cuts turnaround times in routine CSF-based diagnosis. PMID:25180445

Li, Aihong; Grönlund, Elisabeth; Brattsand, Göran

2014-11-01

69

Whole-blood platelet counts with an impedance-type particle counter.  

PubMed

The Clay-Adams Ultra-Flo 100 whole-blood platelet counter provides results that are accurate and precise for platelet counts greater than 20 x 10(9) per liter with virtually zero carryover from one specimen to the next. Comparison of results with those obtained by manual reference and Technicon Autocounter methods shows excellent correlation. The advantage of the Ultra-Flo 100 over the Technicon Autocounter lies in a smaller space requirement in the laboratory, a short start-up time, and minimal maintenance. This makes the Ultra-Flo 100 especially ideal for the stat laboratory. Operating costs of the Ultra-Flo 100 are comparable to those of other methods investigated, but rapid speed of operation has a significant effect on turnaround time. PMID:7352411

Shulman, G; Yapit, M K

1980-01-01

70

How useful are complete blood count and reticulocyte reports to clinicians in Addis Ababa hospitals, Ethiopia?  

PubMed Central

Background Complete blood count (CBC) and reticulocyte (Retics) are routine hematology tests useful for the differential diagnosis of anemia and other medical conditions. However, it has been presumed that they are not used as regular as they should be in medical practice in Addis Ababa hospitals. Methods A hospital-based cross-sectional questionnaire survey was conducted during November-December 2010, in which 408 clinicians participated and their response on the use of CBC and Retics was assessed. The always/frequently (A/F) response was considered to reflect routine use of the CBC/Retics parameters by the clinicians. The Chi square test was used to study statistical associations among different variables. Result Only four of 13 parameters in CBC were frequently or always used by more than 85% of the clinicians. Health Officers were observed to use 12 of the 13 CBC parameters less than the other professional group; interns and residents demonstrated highest use of CBC results. More than a third of clinicians’ preferred white blood cell (WBC) differential report in percentages than the more useful absolute number report. Reticulocyte parameters were not being used by majority of clinicians in patient management. Clinicians rated ‘average’ regarding the adequacy of clinical laboratory methods course they took during medical education. As service users, clinicians indicated mm3 as unit of preference in cell count on the laboratory report form. Conclusion Overall, most clinicians do not use much of the data provided on routine CBC report. Additional research is needed to understand the issue further. Responsible bodies should promote the appropriate use of CBC/Retics reports by clinicians. PMID:24325971

2013-01-01

71

Relation of an elevated white blood cell count after percutaneous coronary intervention to long-term mortality  

Microsoft Academic Search

Increased inflammatory markers are associated with a poor prognosis after percutaneous coronary intervention. Leukocytes play a key role in inflammation, and an increase in white blood cell (WBC) counts is a nonspecific marker of inflammation. In patients undergoing percutaneous coronary intervention, baseline WBC counts independently predict long-term mortality. In a pooled cohort of patients from the Evaluation of c7E3 for

Vivek Rajagopal; Hitinder S Gurm; Deepak L Bhatt; A. Michael Lincoff; James E Tcheng; Dean J Kereiakes; Neal S Kleiman; Gang Jia; Eric J Topol

2004-01-01

72

25 CFR 111.2 - Enrolling non-full-blood children.  

Code of Federal Regulations, 2010 CFR

...2010-04-01 2010-04-01 false Enrolling non-full-blood children. 111.2 Section 111.2 Indians BUREAU...OTHER PER CAPITA PAYMENTS § 111.2 Enrolling non-full-blood children. Where an Indian woman was married to a white...

2010-04-01

73

Lindblad-equation approach for the full counting statistics of work and heat in driven quantum systems  

NASA Astrophysics Data System (ADS)

We formulate the general approach based on the Lindblad equation to calculate the full counting statistics of work and heat produced by driven quantum systems weakly coupled with a Markovian thermal bath. The approach can be applied to a wide class of dissipative quantum systems driven by an arbitrary force protocol. We show the validity of general fluctuation relations and consider several generic examples. The possibilities of using calorimetric measurements to test the presence of coherence and entanglement in the open quantum systems are discussed.

Silaev, Mihail; Heikkilä, Tero T.; Virtanen, Pauli

2014-08-01

74

Evaluation of the veterinary application of a point-of-care device measuring white blood cell counts.  

PubMed

A point-of-care device (POCD) for measuring total white blood cell count was evaluated for feline, canine, equine and bovine blood samples collected into EDTA. Mean biases were -9.2% (range, -12% to -6.3%) for feline samples, 20.2% (range, 15.3-25.1%) for canine samples, -7.1% (range, -8.3% to -5.9%) for equine samples, and 0.7% (range, -1.1% to 2.5%) for bovine samples. The results were influenced by the presence of nucleated red blood cells. The POCD provided precise, reliable data for feline, equine and bovine samples but the values obtained for the canine counts were overestimations. PMID:22503717

Riond, Barbara; Hofmann-Lehmann, Regina; Lutz, Hans

2012-10-01

75

The Color Preferences of Five Hundred and Fifty-Nine Full-Blood Indians  

Microsoft Academic Search

In order to determine the color preferences of different races the author selected for study a group of 559 full-blooded Plains and Plateau Indians, and compared this group with a group of 174 Indians of mixed blood and a group of 560 whites. The materials for the tests consisted of seven Milton Bradley \\

T. R. Garth

1922-01-01

76

Estimating malaria parasite density among pregnant women at central Sudan using actual and assumed white blood cell count  

PubMed Central

Background Microscopic examination using Giemsa-stained thick blood films remains the reference standard for detection of malaria parasites and it is the only method that is widely and practically available for quantifying malaria parasite density. There are few published data (there was no study during pregnancy) investigating the parasite density (ratio of counted parasites within a given number of microscopic fields against counted white blood cells (WBCs) using actual number of WBCs. Methods Parasitaemia was estimated using assumed WBCs (8,000), which was compared to parasitaemia calculated based on each woman’s WBCs in 98 pregnant women with uncomplicated Plasmodium falciparum malaria at Medani Maternity Hospital, Central Sudan. Results The geometric mean (SD) of the parasite count was 12,014.6 (9,766.5) and 7,870.8 (19,168.8) ring trophozoites /?l, P <0.001 using the actual and assumed (8,000) WBC count, respectively. The median (range) of the ratio between the two parasitaemias (using assumed/actual WBCs) was 1.5 (0.6-5), i e, parasitaemia calculated assuming WBCs equal to median (range) 1.5 (0.6-5) times higher than parasitaemia calculated using actual WBCs. There were 52 out of 98 patients (53%) with ratio between 0.5 and 1.5. For 21 patients (21%) this ratio was higher than 2, and for five patients (5%) it was higher than 3. Conclusion The estimated parasite density using actual WBC counts was significantly lower than the parasite density estimated using assumed WBC counts. Therefore, it is recommended to use the patient`s actual WBC count in the estimation of the parasite density. PMID:24386962

2014-01-01

77

Nucleated red blood cells count as first prognostic marker for adverse neonatal outcome in severe preeclamptic pregnancies.  

PubMed

The purpose of this study was to determine acceptability of the nucleated red blood cells counts (NRBC) as early prognostic parameter for adverse outcome in preterm neonates born from pregnancies complicated with severe preeclampsia. We analysed 77 premature newborns who were born from pregnancies with severe preeclampsia during eight years (2004-2011) in our tertiary center. Women with other pregnancy complications were excluded from the study, as well as newborns with malformations and chromosomal anomalies. Newborns were compared according to the count of nucleated red blood cells (NRBC) on the first day of life. Cut off of NRBC was determined at 40 per 100 white blood cells. We analyzed and compared birth weight, gestational age, Apgar scores in 1st and 5th minute, hypoglycemia in first day of life, need for respiratory support, neonatal infection and brain ultrasound findings at the day of discharge between the groups of newborns. We found significantly lower birth weight, gestational age and Apgar scores in case group (NRB C > 40) and significantly higher rate of infections, need for respiratory support, abnormal brain ultrasound findings, morbidity rate and adverse neonatal outcome compared to control newborns group. Increased count of nucleated red blood cells (NRBC) in preterm newborns born from pregnancies with severe preeclampsia seems to be the first significant marker for detecting adverse neonatal outcome. PMID:23213944

Gasparovi?, Vesna Elvedi; Ahmetasevi?, Snjezana Gveri?; Coli?, Ana

2012-09-01

78

Impact of Ambient Air Pollution on the Differential White Blood Cell Count in Patients with Chronic Pulmonary Disease  

PubMed Central

Epidemiologic studies report associations between particulate air pollution and increased mortality from pulmonary diseases.To examine whether the exposure to ambient gaseous and particulate air pollution leads to an alteration of the differential white blood cell count in patients with chronic pulmonary diseases like chronic bronchitis, chronic obstructive pulmonary disease, and asthma. A prospective panel study was conducted in Erfurt, Eastern Germany, with 12 repeated differential white blood cell counts in 38 males with chronic pulmonary diseases. Hourly particulate and gaseous air pollutants and meteorological data were acquired. Mixed models with a random intercept adjusting for trend, meteorology, weekday, and other risk variables were used. In this explorative analysis we found an immediate decrease of polymorphonuclear leukocytes in response to an increase of most gaseous and particulate pollutants. Lymphocytes increased within 24 hours in association with all gaseous pollutants but showed no effect in regard to particulate air pollution. Monocytes showed an increase associated with ultrafine particles, and nitrogen monoxide. The effect had two peaks in time, one 0-23 hours before blood withdrawal and a second one with a time lag of 48-71 hours. The increase of particulate and gaseous air pollution was associated with multiple changes in the differential white blood cell count in patients with chronic pulmonary diseases. PMID:20064088

Bruske, Irene; Hampel, Regina; Socher, Martin M.; Ruckerl, Regina; Schneider, Alexandra; Heinrich, Joachim; Oberdorster, Gunter; Wichmann, H.-Erich; Peters, Annette

2013-01-01

79

Topological quantum-phase coherence in full counting statistics of transport electrons with two-body interaction  

NASA Astrophysics Data System (ADS)

The full counting statistics of electron transport through two parallel quantum dots with antiparallel magnetic fluxes is investigated as a probe to detect the topological quantum-phase coherence (TQPC), which results in the characteristic oscillation of the zero-frequency cumulants including the shot noise and skewness. We show explicitly the phase transition of cumulant spectrum-patterns induced by the topology change of electron path-loops while the pattern period, which depends only on the topology (or Chern number), is robust against the variation of Coulomb interaction and interdot coupling strengths. Most importantly we report for the first time on a new type of TQPC, which is generated by the two-particle interaction and does not exist in the single-particle wave function interference. Moreover, the accurately quantized peaks of Fano-factor spectrum, which characterize the super- and sub-Poissonian shot noises, are of fundamental importance in technical applications similar to the superconducting quantum interference device.

Guo, Xiao-Fang; Xue, Hai-Bin; Liang, Jiu-Qing

2014-08-01

80

Abnormal glucose tolerance, white blood cell count, and telomere length in newly diagnosed, antidepressant-naïve patients with depression.  

PubMed

Chronic mood disorders have been associated with a shortened telomere, a marker of increased mortality rate and aging, and impaired cellular immunity. However, treatment may confound these relationships. We examined the relationship of glucose tolerance, white blood cell count and telomere length to depression in newly diagnosed, antidepressant-naïve patients. Subjects with major depression (n=15), and matched healthy control subjects (n=70) underwent a two-hour oral glucose tolerance test and evaluation of blood cell count and telomere content. The depression group had significantly higher two-hour glucose concentrations and a lower lymphocyte count than control subjects (respective means [SD] for two-hour glucose were 125.0mg/dL [67.9] vs 84.6 [25.6] (p<.001); for lymphocyte count 2.1×10(9)/L [0.6] vs 2.5×10(9)/L [0.7] p=.028). Telomere content was significantly shortened in the depression group (87.9 [7.6]) compared to control subjects (101.0 [14.3]; p<0.01). Abnormal glucose tolerance, lymphopenia and a shortened telomere are present early in the course of depression independently of the confounding effect of antidepressant treatment, supporting the concept of major depression as an accelerated aging disease. PMID:23207109

Garcia-Rizo, Clemente; Fernandez-Egea, Emilio; Miller, Brian J; Oliveira, Cristina; Justicia, Azucena; Griffith, Jeffrey K; Heaphy, Christopher M; Bernardo, Miguel; Kirkpatrick, Brian

2013-02-01

81

Abnormal Glucose Tolerance, White Blood Cell Count, and Telomere Length in Newly Diagnosed, Antidepressant-Na?ve Patients with Depression  

PubMed Central

Chronic mood disorders have been associated with a shortened telomere, a marker of increased mortality rate and ageing, and impaired cellular immunity. However, treatment may confound these relationships. We examined the relationship of glucose tolerance, white blood cell count and telomere length to depression in newly diagnosed, antidepressant-naïve patients. Subjects with major depression (n=15), and matched healthy control subjects (n=70) underwent a two-hour oral glucose tolerance test and evaluation of blood cell count and telomere content. The depression group had significantly higher two-hour glucose concentrations and a lower lymphocyte count than control subjects (respective means [SD] for two-hour glucose were 125.0 mg/dL [67.9] vs 84.6 [25.6] (p<.001); for lymphocyte count 2.1 × 109/L [0.6] vs. 2.5 ×109/L [0.7] p=.028).Telomere content was significantly shortened in the depression group (87.9 [7.6]) compared to control subjects (101.0 [14.3]; p<0.01). Abnormal glucose tolerance, lymphopenia and a shortened telomere are present early in the course of depression independently of the confounding effect of antidepressant treatment, supporting the concept of major depression as an accelerated ageing disease. PMID:23207109

Garcia-Rizo, Clemente; Fernandez-Egea, Emilio; Miller, Brian J.; Oliveira, Cristina; Justicia, Azucena; Griffith, Jeffrey K.; Heaphy, Christopher M.; Bernardo, Miguel; Kirkpatrick, Brian

2012-01-01

82

Prognostic study of continuous variables (white blood cell count, peripheral blast cell count, haemoglobin level, platelet count and age) in childhood acute lymphoblastic leukaemia. Analysis of a population of 1545 children treated by the French Acute Lymphoblastic Leukaemia Group (FRALLE)  

PubMed Central

Many cutpoints have been proposed to categorize continuous variables in childhood acute lymphoblastic leukaemia (white blood cell count, peripheral blast cell count, haemoglobin level, platelet count and age), and have been used to define therapeutic subgroups. This variation in the choice of cutpoints leads to a bias called the ‘Will Rogers phenomenon’. The aim of this study was to analyse variations in the relative risk of relapse or death as a function of continuous prognostic variables in childhood ALL and to discuss the choice of cutpoints. We studied a population of 1545 children with ALL enrolled in three consecutive protocols named FRALLE 83, FRALLE 87 and FRALLE 89. We estimated the risk of relapse or death associated with different values of each continuous prognostic variable by dividing the sample into quintiles of the distribution of the variables. As regards age, a category of children under 1 year of age was distinguished and the rest of the population was divided into quintiles. The floated variance method was used to calculate the confidence interval of each relative risk, including the reference category. The relation between the quantitative prognostic factors and the risk was monotonic for each variable, except for age. For the white blood cell count (WBC), the relation is log linear. The risk associated with WBC values in the upper quintile was 1.9 times higher than that in the lower quintile. The peripheral blast cell count correlated strongly with WBC (correlation coefficient: 0.99). The risk increased with the haemoglobin level, and the risk in the upper quintile was 1.3 times higher than that in the lower quintile. The risk decreased as the platelet count increased: the risk in the lower quintile was 1.2 times higher than that in the upper quintile. The risk increased gradually with increasing age above one year. The small subgroup of patients (2.5% of the population) under 1 year of age at diagnosis had a risk 2.6 times higher than the reference category of patients between 3 and 4.3 years of age. When the risk associated with a quantitative prognostic factor varies monotonously, the selection of a cutpoint is arbitrary and represents a loss of information. Despite this loss of information, such arbitrary categorization may be necessary to define therapeutic stratification. In that case, consensus cutpoints must be defined if one wants to avoid the Will Rogers phenomenon. The cutpoints proposed by the Rome workshop and the NCI are arbitrary, but may represent an acceptable convention. © 2000 Cancer Research Campaign http://www.bjcancer.com PMID:11104555

Donadieu, J; Auclerc, M-F; Baruchel, A; Perel, Y; Bordigoni, P; Landman-Parker, J; Leblanc, T; Cornu, G; Sommelet, D; Leverger, G; Schaison, G; Hill, C

2000-01-01

83

Total and Differential White Blood Cell Counts Predict Eight-Year Incident Stoke in Elderly Japanese-American Men: The Honolulu Heart Program  

PubMed Central

Background: Previous studies have found that a higher white blood cell (WBC) count is associated with incident stroke. There have been few studies examining differential WBC counts in elderly or Asian populations. We studied the association between total and differential WBC counts and incident stroke in an older Asian population. Methods: The Honolulu Heart Program is a prospective population-based study of cardiovascular diseases in Japanese-American men that started in 1965. At exam 4 (1991–93), 3,741 men ages 71–93 years participated, and total and differential WBC counts were measured in 3,569 men using a Coulter counter machine. Data on incident stroke (all strokes [ALL-CVA], thromboembolic [TE-CVA] and hemorrhagic [HEM-CVA]) were available through December 1999 (8 years follow-up) from a comprehensive hospital surveillance system. After excluding 227 subjects with prevalent stroke, 3,342 subjects were divided into quartiles of total WBC, neutrophil (segmented and band), granulocyte (neutrophil, eosinophil and basophil), lymphocyte, and monocyte counts for separate analyses. Results: Age-adjusted incident ALL-CVA rates increased significantly with total WBC quartiles (7.68, 9.04, 9.26, 14.1, per 1,000 person years follow-up, respectively, P = .0014). Relative risks for ALL-CVA for each quartile of total and differential WBC counts were obtained using Cox proportional hazards, using the lowest quartile as the reference group. After full adjustment including age, cardiovascular risk factors, fibrinogen, prevalent CHD, cancer or COPD, and aspirin/NSAID use, the relative risks in the highest quartiles of total WBC, neutrophil, and granulocyte counts were 1.63 (95%CI = 1.05–2.54, P = .03), 2.19 (95%CI = 1.41–3.39, P < .001) and 1.91 (95%CI = 1.25–2.92, P = .003), respectively. These significant associations were also seen for TE-CVA, but not for HEM-CVA. No significant associations were found between lymphocyte or monocyte counts and incident stroke or subtypes. Conclusions: In elderly Japanese-American men, higher total WBC, neutrophil, and granulocyte counts were independent predictors of overall stroke, as well as thromboembolic stroke. Further studies are needed to establish cut-points and treatment options.

Ross, G Webster; Chen, Randi; Bell, Christina; Willcox, Bradley; Abbott, Robert; Launer, Lenore; Kaya, Brock; Masaki, Kamal

2014-01-01

84

Full-field laser Doppler imaging and its physiological significance for tissue blood perfusion  

NASA Astrophysics Data System (ADS)

Using Monte Carlo simulations for a semi-infinite medium representing a skeletal muscle tissue, it is demonstrated that the zero- and first-order moments of the power spectrum for a representative pixel of a full-field laser-Doppler imager behave differently from classical laser-Doppler flowmetry. In particular, the zero-order moment has a very low sensitivity to tissue blood volume changes, and it becomes completely insensitive if the probability for a photon to interact with a moving red blood cell is above 0.05. It is shown that the loss in sensitivity is due to the strong forward scatter of the propagating photons in biological tissues (i.e., anisotropy factor g = 0.9). The first-order moment is linearly related to the root mean square of the red blood cell velocity (the Brownian component), and there is also a positive relationship with tissue blood volume. The most common physiological interpretation of the first-order moment is as tissue blood volume times expectation of the blood velocity (in probabilistic terms). In this sense, the use of the first-order moment appears to be a reasonable approach for qualitative real-time blood flow monitoring, but it does not allow us to obtain information on blood velocity or volume independently. Finally, it is shown that the spatial and temporal resolution trade-off imposed by the CMOS detectors, used in full-field laser-Doppler hardware, may lead to measurements that vary oppositely with the underlying physiological quantities. Further improvements on detectors' sampling rate will overcome this limitation.

Binzoni, T.; Van DeVille, D.

2008-12-01

85

Dynamics of erythrocyte count, hemoglobin, and catalase activity in rat blood in hypokinesia, muscular activity and restoration  

NASA Technical Reports Server (NTRS)

Tests were conducted to prove that muscular exertion (in this instance swimming) of different duration and intensity, as well as hypodynamia, result in an increase of hemoglobin and number of red blood cells in peripheral blood rats. Catalase activity increased with an increase in the duration of swimming, but only up to 6 hr; with 7-9 hr of swimming as well as in hypodynamia, catalase activity decreased. It was also observed that under hypodynamia as well as in 3, 5 and 6 hr exertion (swimming) the color index of blood decreased. Pressure chamber treatment (for 8 min each day for one week), alternating a 2 min negative pressure up to 35 mm Hg with 1 min positive pressure, increased the erythrocyte count and hemoglobin content.

Taneyeva, G. V.; Potapovich, G. M.; Voloshko, N. A.; Uteshev, A. B.

1980-01-01

86

The platelet count in EDTA-anticoagulated blood from patients with thrombocytopenia may be underestimated when measured in routine laboratories.  

PubMed

Spuriously low platelet counts (PCs) can be observed in normal blood samples anticoagulated with ethylenediamine tetra-acetic acid (EDTA)and, much less frequently, with citrate-tris-pyridossalphosphate (CPT),due to time-dependent in vitro platelet agglutination. Accuracy in PC determination is essential as PC is one of the parameters that usually guides treatment for thrombocytopenic patients. PCs of 93 thrombocy to penic patients were measured in EDTA- or CPT-anticoagulated blood samples immediately after sampling (t0) and 90 min (t90) after storage at room temperature. The presence of platelet agglutinates in blood samples was determined by examining blood smears using optical microscopy.PCs decreased at t90 with both anticoagulants. Platelet agglutinates were present at t90 in 27% of EDTA-samples vs. 2% of CPT-samples with decreased PCs (P < 0.001). Based on PCs in EDTA-samples, 15 patients (16%) shifted from a lower bleeding risk at t0 to a higher bleeding risk category at t90 (P 5 0.019), compared to 5 (5%) patients, based on PCs in CPT-samples. Therefore, time-dependent in vitro platelet agglutination in EDTA-blood samples may cause underestimation of PCs in thrombocytopenic patients, possibly leading to improper management. PMID:22674424

Podda, Gian Marco; Pugliano, Mariateresa; Femia, Eti Alessandra; Mezzasoma, Anna Maria; Gresele, Paolo; Carpani, Giovanni; Cattaneo, Marco

2012-07-01

87

Reference intervals of complete blood count constituents are highly correlated to waist circumference: should obese patients have their own "normal values?".  

PubMed

Body mass index (BMI), the prevalent indicator of obesity, is not easily grasped by patients nor physicians. Waist circumference (WC) is correlated to obesity, is better understood and has a stronger relationship to the metabolic syndrome. We compiled WC, complete blood count (CBC) parameters as well as other pertinent data of 6766 25-55-year-old US volunteers sampled in the US National Health and Nutrition Examination Survey, in the years 2005-2010. To determine reference intervals of typical US patients visiting their clinician, we used minimal exclusion criteria. We compiled hemoglobin, red blood cell count, hematocrit, mean corpuscular volume (MCV), mean corpuscular hemoglobin concentration, mean cell hemoglobin (MCH), red cell distribution width (RDW), platelet count, mean platelet volume, and counts of white blood cells (WBC), neutrophils, lymphocytes, monocytes, eosinophils, and basophils. In addition, we also compiled serum C reactive protein and serum iron. The three major US races were studied and reference interval diagrams were constructed for each CBC parameter plotted against WC. WBC count, RDW, lymphocyte, neutrophil, and red blood cell count increase with WC. Conversely, serum iron and MCH and MCV decrease. These relationships may be related to insulin resistance and chronic activation of the immune system and the resulting low-grade inflammatory state. WC is a strong predictor for many CBC parameters, suggesting that WC should be taken into account when evaluating blood count results. Clinicians who take care of obese patients should be aware of altered hematology and investigate and treat accordingly. PMID:24644218

Vuong, Jennifer; Qiu, Yuelin; La, Myanh; Clarke, Gwen; Swinkels, Dorine W; Cembrowski, George

2014-07-01

88

[Accreditation of automated complete blood count by the LH750 Analyzer (Beckman Coulter) in Georges Pompidou Hospital (Paris, France)].  

PubMed

Preliminary evaluation of quantitative clinical laboratory measurements is a prerequisite for the accreditation of clinical laboratories, according to the French Committee of Accreditation guidelines following the European reference Standard EN ISO 15189. Numerous papers have been published regarding biochemistry and immunology. However, data are lacking for automated complete blood count accreditation. We report here our experience at Hôpital européen Georges Pompidou hematology laboratory and present the performance characteristics of two mirrored LH750 Beckman-Coulter analysers, including precision, accuracy and uncertainty of measurement. PMID:24342794

Robinet, Sylvain; Lemaire, Pierre; Louis, Gauthier; Vieillefond, Vincent; Daigneau, Yolande; Gaillaud, Emilie; Vincent, Béatrice; Fischer, Anne-Marie; Siguret, Virginie

2013-01-01

89

White Blood Cell Count in Women: Relation to Inflammatory Biomarkers, Haematological Profiles, Visceral Adiposity, and Other Cardiovascular Risk Factors  

PubMed Central

The role of white blood cell (WBC) count in pathogenesis of diabetes, cardiovascular disease, and obesity-related disorders has been reported earlier. Recent studies revealed that higher WBC contributes to atherosclerotic progression and impaired fasting glucose. However, it is unknown whether variations in WBC and haematologic profiles can occur in healthy obese individuals. The aim of this study is to further evaluate the influence of obesity on WBC count, inflammatory biomarkers, and metabolic risk factors in healthy women to establish a relationship among variables analyzed. The sample of the present study consisted of 84 healthy women with mean age of 35.56±6.83 years. They were categorized into two groups based on their body mass index (BMI): obese group with BMI >30 kg/m2 and non-obese group with BMI <30 kg/m2. We evaluated the relationship between WBC and platelet count (PLT) with serum interleukin 6 (IL-6), C-reactive protein (CRP), angiotensin ? (Ang ?), body fat percentage (BF %), waist-circumference (WC), and lipid profile. WBC, PLT, CRP, and IL-6 in obese subjects were significantly higher than in non-obese subjects (p< 0.05). The mean WBC count in obese subjects was 6.4±0.3 (×109/L) compared to 4.4±0.3 (×109/L) in non-obese subjects (p=0.035). WBC correlated with BF% (r=0.31, p=0.004), CRP (r=0.25, P=0.03), WC (r=0.22, p=0.04), angiotensin ? (r=0.24, p=0.03), triglyceride (r=0.24, p=0.03), and atherogenic index of plasma (AIP) levels (r=0.3, p=0.028) but not with IL-6. Platelet count was also associated with WC and waist-to-hip ratio (p<0.05). Haemoglobin and haematocrit were in consistent relationship with LDL-cholesterol (p<0.05). In conclusion, obesity was associated with higher WBC count and inflammatory parameters. There was also a positive relationship between WBC count and several inflammatory and metabolic risk factors in healthy women. PMID:23617205

Farhangi, Mahdieh Abbasalizad; Keshavarz, Seyyed-Ali; Eshraghian, Mohammadreza; Ostadrahimi, Alireza

2013-01-01

90

Stability of blood cell counts, hematologic parameters and reticulocytes indexes on the Advia A120 hematologic analyzer.  

PubMed

Delayed sample analysis is not a rare circumstance in clinical and laboratory practice, especially when blood samples are shipped to distant centralized laboratories, when the analysis can not be readily performed, or when retesting is appropriate. In this study we sought to evaluate the stability of conventional and new hematologic parameters in blood specimens stored for as long as 24 hours at 4 degrees C. Of the 21 hematologic parameters tested with the use of the Advia 120 hematologic analyzer (Bayer Diagnostics), means for paired samples of specimens differed significantly over the 24-hour storage period for hematocrit, main corpuscular volume, percentage of macrocytes, platelet count, main platelet volume, reticulocyte count and percentage, and reticulocyte hemoglobin content (all P < .01). We noted no significant changes in the other parameters tested or in the white blood cell differential. The overall distribution of the immature reticulocytes fractions remained substantially unchanged, though the high staining-intensity fraction showed a considerable shift from the baseline measure. Bland-Altman plots and limits-of-agreement analysis showed mean biases between -4.8% and 37.2% and relative coefficients of variations ranging from 0.4% to 32.7%. The 95% agreement interval in the set of differences was satisfactory and almost within the current analytic-quality specifications for desirable bias. The results of this investigation suggest that, within certain limitations for parameters derived or calculated from cellular volumes, blood specimens stored for as long as 24 hours at 4 degrees C may be suitable for hematologic testing. PMID:16310516

Lippi, Giuseppe; Salvagno, Gian Luca; Solero, Gian Pietro; Franchini, Massimo; Guidi, Gian Cesare

2005-12-01

91

A quantitative trait locus for faecal worm egg and blood eosinophil counts on chromosome 23 in Australian goats.  

PubMed

Three microsatellite markers on goat chromosome 23 adjacent to the MHC were used to test for quantitative trait loci (QTL) affecting faecal worm egg count (WEC) and leukocyte traits in ten Australian Angora and twelve Australian Cashmere half-sib families (n = 16-57 per family). Data were collected from 280 Angora and 347 Cashmere kids over a 3- and 4-year period. A putative QTL affecting trichostrongyle WEC was found in two small families at the 5% chromosome-wise threshold level. The biggest QTL effect for WEC of 1.65 standard deviations (sigma(p)) was found within the region of OarCP73-BM1258. A significant QTL affecting blood eosinophil counts at the 1% chromosome-wise threshold level was detected at marker BM1258 (at 26 cM) in two Angora and Cashmere families. The magnitude of the putative QTL was 0.69 and 0.85 sigma(p) in Angora and Cashmere families, respectively. Due to the comparatively low power of the study these findings should be viewed as indicative rather than definitive. PMID:20536638

Bolormaa, S; van der Werf, J H J; Walkden-Brown, S W; Marshall, K; Ruvinsky, A

2010-06-01

92

Genetic variants associated with the white blood cell count in 13,923 subjects in the eMERGE Network  

PubMed Central

White blood cell count (WBC) is unique among identified inflammatory predictors of chronic disease in that it is routinely measured in asymptomatic patients in the course of routine patient care. We led a genome-wide association analysis to identify variants associated with WBC levels in 13,923 subjects in the electronic Medical Records and Genomics (eMERGE) Network. We identified two regions of interest that were each unique to subjects of genetically determined ancestry to the African continent (AA) or to the European continent (EA). WBC varies among different ancestry groups. Despite being ancestry specific, these regions were identifiable in the combined analysis. In AA subjects, the region surrounding the Duffy antigen/chemokine receptor gene (DARC) on 1q21 exhibited significant association (p value = 6.71e–55). These results validate the previously reported association between WBC and of the regulatory variant rs2814778 in the promoter region, which causes the Duffy negative phenotype (Fy?/?). A second missense variant (rs12075) is responsible for the two principal antigens, Fya and Fyb of the Duffy blood group system. The two variants, consisting of four alleles, act in concert to produce five antigens and subsequent phenotypes. We were able to identify the marginal and novel interaction effects of these two variants on WBC. In the EA subjects, we identified significantly associated SNPs tagging three separate genes in the 17q21 region: (1) GSDMA, (2) MED24, and (3) PSMD3. Variants in this region have been reported to be associated with WBC, neutrophil count, and inflammatory diseases including asthma and Crohn’s disease. PMID:22037903

McDavid, Andrew; Weston, Noah; Nelson, Sarah C.; Zheng, Xiuwen; Hart, Eugene; de Andrade, Mariza; Kullo, Iftikhar J.; McCarty, Catherine A.; Doheny, Kimberly F.; Pugh, Elizabeth; Kho, Abel; Hayes, M. Geoffrey; Pretel, Stephanie; Saip, Alexander; Ritchie, Marylyn D.; Crawford, Dana C.; Crane, Paul K.; Newton, Katherine; Li, Rongling; Mirel, Daniel B.; Crenshaw, Andrew; Larson, Eric B.; Carlson, Chris S.; Jarvik, Gail P.

2013-01-01

93

Postnatal changes in blood spot 17-hydroxyprogesterone level in healthy preterm and full-term neonates.  

PubMed

Blood spot 17OH-P concentrations were determined in 14 healthy premature (mean birthweight 1439 g, mean gestational age 30 weeks) and full-term newborn infants (mean birthweight 3532 g, mean gestational age 39.2 weeks) during the first five weeks of life to provide reference data for infants with various gestational and postnatal ages. It was demonstrated that with advancing age there was an abrupt fall in 17OH-P from 296.2 +/- 84.1 nmol/l on the first day to 101.2 +/- 19.5 nmol/l on the 7th day (p less than 0.001) and 75.7 +/- 8.7 nmol/l (p less than 0.05) on the 14th day in premature infants. In full-term neonates its initial value is much lower (90.1 +/- 12.5 nmol/l) and its fall during the first week is much less pronounced (51.5 +/- 6.5 nmol/l, p less than 0.01). Comparing the postnatal changes in 17OH-P in the two groups it proved to be significantly higher in premature than in full-term infants at all ages except for the 4th week. When blood spot 17OH-P values were studied as a function of gestational age at the age of 5 days a significant inverse relationship was found between the two parameters. It is assumed that in addition to placental 17OH-P production and perinatal stress, renal salt wasting may also account for the long lasting elevation of 17OH-P plasma level seen in premature infants. PMID:3269260

Sulyok, E; Sólyom, J; Füller, M; Kerekes, L

94

Blood Galactose and Glucose Levels in Mothers, Cord Blood, and 48-Hour-Old Breast-Fed Full-Term Infants  

Microsoft Academic Search

Background: Although galactose is an important component in human lactose, there are few reports of its role in the newborn metabolism. Objective: To determine the relationship of blood galactose and glucose levels in mothers, cord blood, and breast-fed full-term newborn infants. Methods: Maternal and cord vein blood samples were obtained from 27 pregnant women at delivery, and from their breast-fed,

Grasiela Bossolan; Cleide E. P. Trindade; Rodrigo Crespo Barreiros

2007-01-01

95

Standardisation of platelet counting accuracy in blood banks by reference to an automated immunoplatelet procedure: comparative evaluation of Cell-Dyn CD4000 impedance and optical platelet counts  

Microsoft Academic Search

Prophylactic and therapeutic platelet transfusions are increasingly used for patients with conditions associated with thrombocytopenia in order to prevent the development of potentially life threatening bleeding. These clinical strategies have led to a significant expansion in platelet unit manufacture, and this now represents a major resource and cost commitment for blood banks. As part of the manufacturing process, blood banks

Berit Johannessen; Torhild Haugen; Colin Stephen Scott

2001-01-01

96

Genome-Wide Association Study of White Blood Cell Count in 16,388 African Americans: the Continental Origins and Genetic Epidemiology Network (COGENT)  

Microsoft Academic Search

Total white blood cell (WBC) and neutrophil counts are lower among individuals of African descent due to the common African-derived “null” variant of the Duffy Antigen Receptor for Chemokines (DARC) gene. Additional common genetic polymorphisms were recently associated with total WBC and WBC sub-type levels in European and Japanese populations. No additional loci that account for WBC variability have been

Alexander P. Reiner; Guillaume Lettre; Michael A. Nalls; Santhi K. Ganesh; Rasika Mathias; Melissa A. Austin; Eric Dean; Sampath Arepalli; Angela Britton; Zhao Chen; David Couper; J. David Curb; Charles B. Eaton; Myriam Fornage; Struan F. A. Grant; Tamara B. Harris; Dena Hernandez; Naoyuki Kamatini; Brendan J. Keating; Michiaki Kubo; Andrea LaCroix; Leslie A. Lange; Simin Liu; Kurt Lohman; Yan Meng; Emile R. Mohler; Solomon Musani; Yusuke Nakamura; Christopher J. ODonnell; Yukinori Okada; Cameron D. Palmer; George J. Papanicolaou; Kushang V. Patel; Andrew B. Singleton; Atsushi Takahashi; Hua Tang; Herman A. Taylor; Kent Taylor; Cynthia Thomson; Lisa R. Yanek; Lingyao Yang; Elad Ziv; Alan B. Zonderman; Aaron R. Folsom; Michele K. Evans; Yongmei Liu; Diane M. Becker; Beverly M. Snively; James G. Wilson

2011-01-01

97

Cine Computed Tomography Angiography Evaluation of Blood Flow for Full Face Transplant Surgical Planning  

PubMed Central

Objective: Screening for full face transplantation candidates includes computed tomographic vascular mapping of the external carotid distribution for potential arterial and venous anastomoses. The purpose of this study is to illustrate the benefits and drawbacks of cine computed tomographic imaging for preoperative vascular mapping compared with best arterial and venous phase static images. Methods: Two image data sets were retrospectively created and compared for diagnostic findings. The first set of images was the clinical cine computed tomographic acquisition including all phases. The second set of images was composed of the best arterial and best venous phases extracted from the cine loop and determined by the quality of contrast enhancement. For each patient, the benefits and drawbacks of the cine loop were documented in consensus by a plastic surgeon and a radiologist. Results: Cine loop analysis identified retrograde arterial filling not illustrated on the static images alone. Cine assessment identified most of the major vessels necessary for surgery, whereas the static images depicted small vessels more clearly, particularly in the crowded vessel takeoffs. Conclusions: Cine computed tomographic images provide data on direction of blood flow, which is important for preoperative planning. Combination of cine computed tomographic and the best static images will allow comprehensive vascular assessment necessary for future successful full face transplantation. PMID:23308304

Sisk, Geoffroy C.; Kumamaru, Kanako K.; Schultz, Kurt; Bueno, Ericka M.; Diaz-Siso, J. Rodrigo; George, Elizabeth; Redjaee, Marta M.; Mitsouras, Dimitrios; Steigner, Michael L.; Pomahac, Bohdan; Rybicki, Frank J.

2012-01-01

98

Chronic khat (Catha edulis) and alcohol marginally alter complete blood counts, clinical chemistry, and testosterone in male rats  

PubMed Central

Introduction Khat (Catha edulis) is a recreational psychoactive drug with psychostimulant properties. While the use of this drug is widespread in eastern Africa, including the Horn of Africa, surveys and anecdotal data show that its use has become cosmopolitan, with users now living in Europe and North America as well. Recent data in Uganda suggest an increasing pattern of simultaneous khat and ethanol use particularly among young adults. However, the effects of this pattern of use remain largely unknown, even though long-term use of either drug alone is known to be harmful. The aim of this study was to examine the toxic effects of simultaneous chronic administration of khat and ethanol on hematological parameters, clinical chemistry, and testosterone in a rat model. Methods Adult male Sprague-Dawley rats were randomly assigned to one of six dose groups: 2 g/kg khat; 4 g/kg khat; 4 g/kg ethanol; combined khat and ethanol (4 g/kg each); control; and an untreated group. Treatments were given by gavage twice daily for 28 days, followed by determination of hematological parameters, blood clinical chemistry, and testosterone. Results Ethanol alone significantly reduced platelet counts compared to control-, untreated and low-dose khat-treated rats; conversely low-dose khat significantly increased both the hemoglobin and hematocrit values, while ethanol alone also significantly increased the hemoglobin value compared to controls. Simultaneous khat and ethanol administration per se did not produce more toxic consequences in chronic use than either drug alone. Conclusion Chronic short-term khat use and ethanol dependence individually produce note-worthy effects on the blood, but not on clinical chemistry or testosterone. Chronic short-term combined khat and ethanol use does not produce more toxic effects compared to use of either drug alone. This provides an opportunity for appropriate clinical interventions to avert the chronic long-term effects that result from use of these drugs of abuse. PMID:24348075

Alele, Paul E; Ajayi, Abayomi M; Imanirampa, Lawrence

2013-01-01

99

Era of blood component therapy: time for mandatory pre-donation platelet count for maximizing donor safety and optimizing quality of platelets.  

PubMed

Blood bank regulatory agencies including the Drug and Cosmetics Act (DCA) of India do not mandate a predonation platelet count in whole blood donation. Mandating such practice will definitely optimize the quality of random donor platelets (RDP) in terms of platelet yield and patient therapeutic benefit. We observed poor platelet yield in RDP concentrates prepared at our center with a significant number not meeting the DCA guideline of ? 4.5 × 10(10) per bag processed from 450 ml of whole blood. Therefore we planned this study to evaluate the pre-donation hematological values in our blood donor population and effect of these values on the quality of platelet concentrates. The prospective study included 221 blood donors eligible for donating 450 ml of whole blood (WB). Following the departmental standard operating procedure (SOP) RDPs were prepared using the 'Top & Bottom' quadruple bag system and automated component extractor. Quality of RDP was assessed as per departmental protocol. All results were recorded and subsequently transcribed to SPSS working sheet. A significant (p<0.001) decrement of donor blood counts has been observed after WB donation. Mean donor Hb and platelets reduced by 0.72 g/dl and 22.1 × 10(6)/ml respectively. Quality of RDPs in terms of platelet yield was significantly better (p<0.001) when donor platelet count was >200 × 10(6)/ml. Although platelet yield significantly correlated with the donor platelet count however quality of RDPs in terms of red cell contamination showed no correlation with the donor hematocrit. Platelet yield in random donor platelets is a concern in Eastern India. A platelet yield of 4.5 × 10(10) per bag as mandated by the DCA of India was only achieved when the donor platelet count was >200 × 10(6)/ml. Posttransfusion platelet recovery (PPR) was unsatisfactory in the transfused patient. Introduction of pre-donation platelet count in whole blood donation will maximize donor safety and optimize patient platelet transfusion management. PMID:23928130

Das, Sudipta Sekhar; Zaman, R U; Biswas, Dipak

2013-12-01

100

Elevated white blood cell count is associated with higher risk of glucose metabolism disorders in middle-aged and elderly Chinese people.  

PubMed

White blood cell (WBC) count has been associated with diabetic risk, but whether the correlation is independent of other risk factors has hardly been studied. Moreover, very few such studies with large sample sizes have been conducted in Chinese. Therefore, we investigated the relationship between WBC count and glucose metabolism in china. We also examined the relevant variables of WBC count. A total of 9,697 subjects (mean age, 58.0 ± 9.1 years) were recruited. The subjects were classified into four groups, including subjects with normal glucose tolerance, isolated impaired fasting glucose, impaired glucose tolerance and type 2 diabetes mellitus (T2DM). We found that WBC count increased as glucose metabolism disorders exacerbated. WBC count was also positively correlated with waist hip ratio, body mass index, smoking, triglycerides, glycosylated haemoglobin A1c (HbA1c) and 2-h postprandial glucose. In addition, high density lipoprotein and the female gender were inversely correlated with WBC levels. In patients with previously diagnosed T2DM, the course of T2DM was not correlated with WBC count. Our findings indicate that elevated WBC count is independently associated with worsening of glucose metabolism in middle-aged and elderly Chinese. In addition, loss of weight, smoking cessation, lipid-modifying therapies, and control of postprandial plasma glucose and HbA1c may ameliorate the chronic low-grade inflammation. PMID:24852600

Jiang, Hua; Yan, Wen-Hua; Li, Chan-Juan; Wang, An-Ping; Dou, Jing-Tao; Mu, Yi-Ming

2014-05-01

101

Elevated White Blood Cell Count Is Associated with Higher Risk of Glucose Metabolism Disorders in Middle-Aged and Elderly Chinese People  

PubMed Central

White blood cell (WBC) count has been associated with diabetic risk, but whether the correlation is independent of other risk factors has hardly been studied. Moreover, very few such studies with large sample sizes have been conducted in Chinese. Therefore, we investigated the relationship between WBC count and glucose metabolism in china. We also examined the relevant variables of WBC count. A total of 9,697 subjects (mean age, 58.0 ± 9.1 years) were recruited. The subjects were classified into four groups, including subjects with normal glucose tolerance, isolated impaired fasting glucose, impaired glucose tolerance and type 2 diabetes mellitus (T2DM). We found that WBC count increased as glucose metabolism disorders exacerbated. WBC count was also positively correlated with waist hip ratio, body mass index, smoking, triglycerides, glycosylated haemoglobin A1c (HbA1c) and 2-h postprandial glucose. In addition, high density lipoprotein and the female gender were inversely correlated with WBC levels. In patients with previously diagnosed T2DM, the course of T2DM was not correlated with WBC count. Our findings indicate that elevated WBC count is independently associated with worsening of glucose metabolism in middle-aged and elderly Chinese. In addition, loss of weight, smoking cessation, lipid-modifying therapies, and control of postprandial plasma glucose and HbA1c may ameliorate the chronic low-grade inflammation. PMID:24852600

Jiang, Hua; Yan, Wen-Hua; Li, Chan-Juan; Wang, An-Ping; Dou, Jing-Tao; Mu, Yi-Ming

2014-01-01

102

Full-field high-speed laser Doppler imaging system for blood-flow measurements  

NASA Astrophysics Data System (ADS)

We describe the design and performance of a new full-field high-speed laser Doppler imaging system developed for mapping and monitoring of blood flow in biological tissue. The total imaging time for 256x256 pixels region of interest is 1.2 seconds. An integrating CMOS image sensor is utilized to detect Doppler signal in a plurality of points simultaneously on the sample illuminated by a divergent laser beam of a uniform intensity profile. The integrating property of the detector improves the signal-to-noise ratio of the measurement, which results in high-quality flow-images provided by the system. The new technique is real-time, non-invasive and the instrument is easy to use. The wide range of applications is one of the major challenges for a future application of the imager. High-resolution high-speed laser Doppler perfusion imaging is a promising optical technique for diagnostic and assessing the treatment effect of the diseases such as e.g. atherosclerosis, psoriasis, diabetes, skin cancer, allergies, peripheral vascular diseases, skin irritancy and wound healing. We present some biological applications of the new imager and discuss the perspectives for the future implementations of the imager for clinical and physiological applications.

Serov, Alexandre; Lasser, Theo

2006-02-01

103

Effects of experimental acute myocardial infarction on blood cell counts and plasma biochemical values in a nude rat model (Crl:NIH-Fox1 RNU )  

Microsoft Academic Search

To determine the clinical pathology parameters in nude rats (Crl:NIH-Fox1RNU) following experimental induction of acute myocardial infarction (AMI), 50 male adult nude rats weighing 250–350 g were used.\\u000a Complete blood count, total and differential leukocyte counts, plasma total protein, albumin, glucose, urea, creatinine, total\\u000a bilirubin, aspartate aminotransferase, alkaline phosphatase, and gamma-glutamyl transpeptidase were determined before (time\\u000a zero, T0), 1, and 5 days

Zuhair Bani Ismail; Mahmoud Abu Abeeleh; Khaled R. Alzaben; Sami A. Abu-Halaweh; Abdel Karim S. Aloweidi; Iyad A. Al-Ammouri; Mohamed K. Al-Essa; Samir K. Jabaiti; Moaath M. Alsmady; Ahmad Al-Majali

2009-01-01

104

Approaches to Determination of a Full Profile of Blood Group Genotypes: Single Nucleotide Variant Mapping and Massively Parallel Sequencing  

PubMed Central

The number of blood group systems, currently 35, has increased in the recent years as genetic variations defining red cell antigens continue to be discovered. At present, 44 genes and 1568 alleles have been defined as encoding antigens within the 35 blood group systems. This paper provides a brief overview of two genetic technologies: single nucleotide variant (SNV) mapping by DNA microarray and massively parallel sequencing, with respect to blood group genotyping. The most frequent genetic change associated with blood group antigens are SNVs. To predict blood group antigen phenotypes, SNV mapping which involves highly multiplexed genotyping, can be performed on commercial microarray platforms. Microarrays detect only known SNVs, therefore, to type rare or novel alleles not represented in the array, further Sanger sequencing of the region is often required to resolve genotype. An example discussed in this article is the identification of rare and novel RHD alleles in the Australian population. Massively parallel sequencing, also known as next generation sequencing, has a high-throughput capacity and maps all points of variation from a reference sequence, allowing for identification of novel SNVs. Examples of the application of this technology to resolve the genetic basis of orphan blood group antigens are presented here. Overall, the determination of a full profile of blood group SNVs, in addition to serological phenotyping, provides a basis for provision of compatible blood thus offering improved transfusion safety. PMID:25408849

McBean, Rhiannon S.; Hyland, Catherine A.; Flower, Robert L.

2014-01-01

105

A white blood cell count in the normal concentration range is independently related to cardiorespiratory fitness in apparently healthy Korean men  

Microsoft Academic Search

Despite the documented health benefits of physical activity, the mechanism whereby physical activity prevents cardiovascular disease is incompletely understood. In the present study, we investigated the relationship between white blood cell (WBC) count and cardiorespiratory fitness (V?o2max) after adjusting for several well-known cardiovascular risk factors. Subjects who visited our health promotion center for a medical checkup and treadmill test (n

Dong-Jun Kim; Jung-Hyun Noh; Byung-Wan Lee; Yoon-Ho Choi; Jae-Hoon Jung; Yong-Ki Min; Myung-Shik Lee; Moon-Kyu Lee; Kwang-Won Kim

2005-01-01

106

Dynamical analysis of erythrocytes under the assumption of cross-spectral coherence between blood cell counts and the Dst  

E-print Network

Dynamical analysis of erythrocytes under the assumption of cross-spectral coherence between blood type of blood cell are expected to reflect the intrinsic dynamics of the hematologic system and its for the transport of oxygen, coagulation and the immune response respectively. In the healthy subject, blood cell

Dasso, Sergio

107

Blood differential  

MedlinePLUS

Differential; White blood cell differential count ... The health care provider will take blood from your vein. The blood collects into an airtight container. In infants or a young child, blood will be taken from a ...

108

Erythrocytes and the regulation of human skeletal muscle blood flow and oxygen delivery: role of erythrocyte count and oxygenation state of haemoglobin  

PubMed Central

Blood flow to dynamically contracting myocytes is regulated to match O2 delivery to metabolic demand. The red blood cell (RBC) itself functions as an O2 sensor, contributing to the control of O2 delivery by releasing the vasodilators ATP and S-nitrosohaemoglobin with the offloading of O2 from the haemoglobin molecule. Whether RBC number is sensed remains unknown. To investigate the role of RBC number, in isolation and in combination with alterations in blood oxygenation, on muscle and systemic perfusion, we measured local and central haemodynamics during one-legged knee-extensor exercise (?50% peak power) in 10 healthy males under conditions of normocythaemia (control), anaemia, anaemia + plasma volume expansion (PVX), anaemia + PVX + hypoxia, polycythaemia, polycythaemia + hyperoxia and polycythaemia + hypoxia, which changed either RBC count alone or both RBC count and oxyhaemoglobin. Leg blood flow (LBF), cardiac output (Q) and vascular conductance did not change with either anaemia or polycythaemia alone. However, LBF increased with anaemia + PVX (28 ± 4%) and anaemia + PVX + hypoxia (46 ± 6%) and decreased with polycythaemia + hyperoxia (18 ± 5%). LBF and Q with anaemia + PVX + hypoxia (8.0 ± 0.5 and 15.8 ± 0.7 l min?1, respectively) equalled those during maximal knee-extensor exercise. Collectively, LBF and vascular conductance were intimately related to leg arterial–venous (a–v) O2 difference (r2 = 0.89–0.93; P < 0.001), suggesting a pivotal role of blood O2 gradients in muscle microcirculatory control. The systemic circulation accommodated to the changes in muscle perfusion. Our results indicate that, when coping with severe haematological challenges, local regulation of skeletal muscle blood flow and O2 delivery primarily senses alterations in the oxygenation state of haemoglobin and, to a lesser extent, alterations in the number of RBCs and haemoglobin molecules. PMID:16439430

Gonzalez-Alonso, Jose; Mortensen, Stefan P; Dawson, Ellen A; Secher, Niels H; Damsgaard, Rasmus

2006-01-01

109

Detection of colon polyps by a novel, polymer pattern-based full blood test  

PubMed Central

Numerous studies have shown that early screening for the presence of pre-cancerous colon polyps and their subsequent removal decreases the risk of developing colon cancer. Colonoscopy is currently the most effective screening method, but due to the invasive nature of the procedure many patients avoid forgo testing. Futhermore, the procedure itself requires perfect execution by the gastroenterologist. Against this backdrop, a non-invasive blood screening method for the detection of colon polyps that has higher sensitivity than current screening techniques would be beneficial in the early identification of patients at risk for colon cancer. A prospective, double-blinded, controlled clinical study was designed to demonstrate the diagnostic performance of Polyp Specific Polymer analysis, a novel laboratory methodology. The primary objective of this clinical trial was to estimate the diagnostic accuracy of the Polyp Specific Polymer analysis for colon polyps using colonoscopy and histological tests as the diagnostic accuracy standards. Secondary objectives of this trial included estimating positive and negative predictive values for colon polyps, investigating reliability, determining covariates influencing diagnostic accuracy and obtaining absolute and relative frequencies of valid test results. In patients undergoing screening colonoscopy and histology examination, a sensitivity of 72.4% and a specificity of 62.3% could be proven. These results indicate that using this improved screening method it is possible to effectively identify the highest-risk candidates for endoscopy, thereby advancing the goal of decreasing the incidence or mortality of colorectal cancer in the selected population. Moreover, this diagnostic tool has potential socio-economic implications, conserving healthcare resources by enabling higher patient selectivity for endoscopy and eventual transfer to curative prevention via polypectomy. By combining the best-established low-risk screening elements together with a validated, highly sensitive blood test as described in this study, a steadfast increase in the estimation of colorectal cancer-risk before colonoscopy can be expected. PMID:24180554

2013-01-01

110

70-year old female patient with mismatch between hematocrit and hemoglobin values: the effects of cold agglutinin on complete blood count  

PubMed Central

Introduction: There are a number of pre-analytical and analytical factors, which cause false results in the complete blood count. The present case identifies cold agglutinins as the cause for the mismatch between hematocrit and hemoglobin values. Materials and methods: 70-year old female patient had a history of cerebrovascular diseases and rheumatoid arthritis. During routine laboratory examination, the patient had normal leukocyte and platelet counts; however, the hemoglobin (Hb: 105 g/L) and hematocrit (HCT: 0.214 L/L) results were discordant. Hemolysis, lipemia and cold agglutinin were evaluated as possible reasons for the mismatch between hematocrit and hemoglobin values. Results: First blood sample was slightly hemolysed. Redrawn sample without hemolysis or lipemia was analyzed but the mismatch became even more distinct (Hb: 104 g/L and HCT: 0.08 L/L). In this sample, the titration of the cold agglutinin was determined and found to be positive at 1:64 dilution ratios. After an incubation of the sample at 37°C for 2 hours, reversibility of agglutination was observed. Conclusion: We conclude that cold agglutinins may interfere with the analysis of erythrocyte and erythrocyte-related parameters (HCT, MCV, MCH and MCHC); however, Hb, leukocyte and platelet counts are not affected. PMID:25351358

Ercan, Serif; Cal?skan, Mustafa; Koptur, Erhan

2014-01-01

111

Comparison of platelet clumping and complete blood count results with Sysmex XT-2000iV in feline blood sampled on EDTA or EDTA plus CTAD (citrate, theophylline, adenosine and dipyridamole).  

PubMed

False thrombocytopenia may result from platelet aggregation, especially in feline ethylenediamine tetra-acetic acid (EDTA) blood specimens. Citrate, theophylline, adenosine and dipyridamole (CTAD) was added to 46 feline EDTA specimens to test its anti-aggregation action. Platelet aggregation was estimated from blood films and a complete blood count was performed with a Sysmex XT-2000iV analyser. Platelet aggregation score was >2 in 11/46 EDTA tubes and only in one EDTA+CTAD specimen. The platelet count was higher in all CTAD-supplemented tubes except one, medians measured by cytometry being 225.5 × 10(9)/l and 249.0 × 10(9)/l in EDTA and EDTA+CTAD, respectively (P = 0.007). Adding CTAD had statistically and analytically significant but moderate effects on other blood variables, the most intense variations being observed for reticulocytes (about 3% higher in EDTA specimens) and reticulocyte indexes. Addition of CTAD to EDTA when sampling feline blood is a useful option to reduce platelet clumping. PMID:22079363

Granat, Fanny; Geffré, Anne; Braun, Jean-Pierre; Trumel, Catherine

2011-12-01

112

Blood  

MedlinePLUS

... mysterious, life-sustaining fluid called blood. What Is Blood and What Does It Do? Two types of ... mixture of blood cells and plasma. Continue Red Blood Cells Red blood cells (RBCs, and also called ...

113

Blood  

MedlinePLUS

... solid part of your blood contains red blood cells, white blood cells, and platelets. Red blood cells deliver oxygen from your lungs to your tissues and organs. White blood cells fight infection and are part of your body's ...

114

Cutaneous presentation of chronic lymphocytic leukemia as unique extramedullar involvement in a patient with normal peripheral blood lymphocyte count (monoclonal B-cell lymphocytosis).  

PubMed

Skin infiltration by chronic lymphocytic leukemia (CLL) is very rare and almost all reported cases occur in advanced stage. We report a patient with no relevant past medical history who presented with cutaneous erythematous plaques. A punch biopsy showed typical CLL morphologic and immunophenotypic features. Subsequent studies revealed a normal lymphocyte count in peripheral blood, and there was no evidence of lymphadenopathy or organomegaly. Flow cytometry demonstrated a clonal B-cell population both in the bone marrow and peripheral blood (1.60 × 10(9)/l) with a CLL phenotype, but it did not fulfill required criteria for CLL diagnosis. Without cutaneous involvement, this case should be classified as monoclonal B-cell lymphocytosis. PMID:23639136

Tapia, Gustavo; Mate, José-Luis; Fuente, María-José; Navarro, José-Tomás; Fernández-Figueras, Maria-Teresa; Juncà, Jordi; Ferrándiz, Carlos; Ariza, Aurelio

2013-08-01

115

[The changes in complete blood count in patients treated with sunitinib malate for metastatic clear cell renal cell carcinoma].  

PubMed

Renal cell carcinoma (RCC) accounts for approximately 3% of adult malignancies. For stage I - III RCC surgery is the primary treatment. Systemic therapy is used in the patients with disseminated disease (stage IV). Sunitinib malate is commonly used in the patients with clear cell renal cell carcinoma (ccRCC) rated as 'low' or 'intermediate' risk according to the Motzer scale. Treatment with sunitinib malate is associated with myelotoxicity. To assess its clinical significance we conducted a pilot study in a group of 10 patients. We noticed a gradual decrease in the mean haemoglobin level during subsequent treatment cycles. Alternations in the platelet count were of no clinical significance. Episodes of the neutropenia were noticed in the study group. In some patients neutrophil count decreased to the level that put them at risk of the infectious complications. PMID:24455830

Kucharz, Jakub; Micha?owska-Kaczmarczyk, Anna; Streb, Joanna; Kuzniewski, Marek; Herman, Roman M; Krzemieniecki, Krzysztof

2013-01-01

116

Crazy Counting  

NSDL National Science Digital Library

Let's count shapes and animals! Let's go to the farm to do some Apple Counting. Then let's have some Counting Fun with shapes and animals. Afterward let's grab a fishing pole and do some Fishy Counting! ...

Terch, Ms.

2010-01-27

117

[The influence of melatonin and epithalon on blood leukocyte count and leukocyte alkaline phosphatase in rats under different lighting conditions during ontogenesis].  

PubMed

The effect of pineal body hormone melatonin and synthetic tetrapeptide epithalon (Ala-Glu-Asp-Gly) under different light conditions on leucocytes differential count in rats were investigated. It has been established that melatonin and epithalon decrease the level of blood leucocytes and relative content of band neutrophils in 12 months rats which was higher in the constant light more than in other photoperiod. The melatonin prevents age-specific decreasing blood lymphocytes level in standard photoperiod (12 h light/12 h darkness). Contrary to melatonin, epithalon significantly reduces the number of lymphocytes and increases the number of neutrophils in some age period. The leucocytes alkaline phosphatase activity was increased during aging. Constant light in compare with other light conditions promotes early increasing of alkaline phosphatase activity (at 12 months), associated with accelerated development of pathological process in organism. The melatonin and epithalon adjacency effect on increasing of alkaline phosphatase activity under the standard as well as natural light condition demonstrate homeostatic character of geroprotectors action furthermore depend on leucocytes functional status. PMID:19432172

Uzenbaeva, L B; Vinogradova, I A; Golubeva, A G; Niuppieva, M G; Iliukha, V A

2008-01-01

118

[The dynamics of the ectoparasite count and the protein level in the blood serum of infested carp under experimental conditions].  

PubMed

Carps of one and two years age used for laboratory experiments were collected in winter time. 7 groups of carps of one year age were examined each 10th day during 70 days and 5 groups of two years age were examined each 15 days during 75 days. In carps of one year age the increase of different parasites was observed in different time: Dactylogyrus extensus--after 40 and 70 days, Icthyophthirius multifiliis--after 50 days, Trichodina sp.--after 60 days. In carps of two years age the increase of all parasite groups observed after 45 days, extremely great number of D. extensus was recorded after 60-70 days. Contents of proteins in a blood plasma of both age groups of carps is reliably decreased when the number of parasites is increased. Fluctuations of parasite abundance on the body and gills and some morphophysiological indices in carps of one year age in a control and in conditions of starvation were examined. PMID:10206854

Kurovskaia, L Ia

1998-01-01

119

Reduced birth weight in relation to pesticide mixtures detected in cord blood of full-term infants.  

PubMed

Previous research has shown that prenatal exposure to pesticides may be associated with decreased fetal growth. The specific pesticides investigated and results reported across studies have been inconsistent, and there is a mounting need for the consideration of mixtures rather than individual agents in studies of health outcomes in relation to environmental exposures. There are also many individual pesticides that have not been investigated in human health studies to date. We conducted a pilot study in rural Zhejiang province, China, measuring 20 non-persistent pesticides (10 insecticides, 6 herbicides, 3 fungicides, and 1 repellant) in umbilical cord blood of 112 full term (> 37 weeks) infants. The pesticides detected with the greatest frequency were diethyltoluamide (DEET) (73%), a repellant, and vinclozolin (49%), a fungicide. The samples had detectable concentrations for a mean of 4.6 pesticides (SD=1.9) with a maximum of 10. Adjusting for potential confounders, newborn birth weight was inversely associated with the number of pesticides detected in cord blood (p=0.04); birth weight decreased by a mean of 37.1g (95% CI, -72.5 to -1.8) for each detected pesticide. When assessing relationships by pesticide type, detection of fungicides was also associated with decreased birth weight (adjusted ?=-116 g [95% CI, -212 to -19.2]). For individual pesticides analyzed as dichotomous (detect vs. non-detect) variables, only vinclozolin (adjusted ?=-174 g [95% CI, -312 to -36.3]) and acetochlor (adjusted ?=-165 g [95% CI, -325 to -5.7]) were significantly associated with reduced birth weight. No significant associations were seen between birth weight and individual pesticides assessed as continuous or 3-level ordinal variables. Our findings from this pilot investigation suggest that exposure to fungicides may adversely impact fetal growth. Exposure to mixtures of multiple pesticides is also of concern and should be explored in addition to individual pesticides. Additional research is needed to establish causality and to understand the function and impact of fungicides and pesticide mixtures on fetal development. PMID:22796478

Wickerham, Erin L; Lozoff, Betsy; Shao, Jie; Kaciroti, Niko; Xia, Yankai; Meeker, John D

2012-10-15

120

Reduced birth weight in relation to pesticide mixtures detected in cord blood of full-term infants  

PubMed Central

Previous research has shown that prenatal exposure to pesticides may be associated with decreased fetal growth. The specific pesticides investigated and results reported across studies have been inconsistent, and there is a mounting need for the consideration of mixtures rather than individual agents in studies of health outcomes in relation to environmental exposures. There are also many individual pesticides that have not been investigated in human health studies to date. We conducted a pilot study in rural Zhejiang province, China, measuring 20 non-persistent pesticides (10 insecticides, 6 herbicides, 3 fungicides, and 1 repellant) in umbilical cord blood of 112 full term (>37 weeks) infants. The pesticides detected with the greatest frequency were diethyltoluamide (DEET) (73%), a repellant, and vinclozolin (49%), a fungicide. The samples had detectable concentrations for a mean of 4.6 pesticides (SD=1.9) with a maximum of 10. Adjusting for potential confounders, newborn birth weight was inversely associated with the number of pesticides detected in cord blood (p = 0.04); birth weight decreased by a mean of 37.1 grams (95% CI, ?72.5 to ?1.8) for each detected pesticide. When assessing relationships by pesticide type, detection of fungicides was also associated with decreased birth weight (adjusted ? = ?116 grams [95% CI, ?212 to ?19.2]). For individual pesticides analyzed as dichotomous (detect vs. non-detect) variables, only vinclozolin (adjusted ? = ?174 grams [95% CI, ?312 to ?36.3] and acetochlor (adjusted ? = ?165 grams [95% CI, ?325 to ?5.7]) were significantly associated with reduced birth weight. No significant associations were seen between birth weight and individual pesticides assessed as continuous or 3-level ordinal variables. Our findings from this pilot investigation suggest that exposure to fungicides may adversely impact fetal growth. Exposure to mixtures of multiple pesticides is also of concern and should be explored in addition to individual pesticides. Additional research is needed to establish causality and to understand the function and impact of fungicides and pesticide mixtures on fetal development. PMID:22796478

Wickerham, Erin L.; Lozoff, Betsy; Shao, Jie; Kaciroti, Niko; Xia, Yankai; Meeker, John D.

2012-01-01

121

Diagnostic Usefulness of White Blood Cell and Absolute Neutrophil Count for Postoperative Infection after Anterior Cervical Discectomy and Fusion Using Allograft and Demineralized Bone Matrix  

PubMed Central

Study Design Prospective study. Purpose We investigated normative temporal levels of white blood cell (WBC) and absolute neutrophil count (ANC) in uncomplicated anterior cervical discectomy and fusion (ACDF) using allograft and demineralized bone matrix (DBM). Overview of Literature No study has investigated the diagnostic usefulness of WBC and ANC for postoperative infection following ACDF using allograft and DBM. Methods Blood samples of 85 patients, who underwent one or two-level ACDF, were obtained and evaluated before surgery and on the first, third, fifth, seventh, fourteenth, thirtieth, and ninetieth postoperative days. No infection was found in all patients for at least one year follow-up period. Results Mean WBC and ANC values increased significantly and reached peak levels on the first postoperative day. The peaked levels rapidly decreased but still remained elevated above the preoperative levels on the third postoperative day. The levels returned close to the preoperative levels on the fifth postoperative day. The mean WBC and ANC values did not get out of their normal reference ranges throughout the follow-up periods. One-level and two-level ACDF exhibited a similar course of postoperative changes in WBC and ANC values and no significant difference in mean levels of WBC and ANC throughout the follow-up periods. Conclusions Uncomplicated ACDF using allograft and DBM showed normal values of WBC and ANC during the early postoperative period. Therefore, significant abnormal values of WBC and ANC at an early postoperative period suggest the possibility of the development of acute postoperative infection after ACDF using allograft and DBM. PMID:24066211

Kong, Chae-Gwan; Kim, Young-Yul; Ahn, Chi Young

2013-01-01

122

Counting Books  

NSDL National Science Digital Library

The web site provides instructions for making counting books. Suggestions for using the completed books for counting one at a time, skip-counting, fractions and introducing addition and subtraction are given. Children should be able to write the numbers from 1 to 10 before beginning this activity.

2010-01-01

123

An algorithm for utilizing peripheral blood CD34 count as a predictor of the need for plerixafor in autologous stem cell mobilization--cost-effectiveness analysis.  

PubMed

Certain patients who receive granulocyte colony-stimulating factor (GCSF) for autologous hematopoietic stem cell (AHSC) collection fail to mobilize well enough to proceed with transplant. When plerixafor is used with GCSF, the likelihood of achieving the CD34? stem cell target in fewer collections is higher; plerixafor use in all patients is unlikely to be cost-effective. This study retrospectively evaluated the effectiveness of utilizing a peripheral blood CD34? stem cell count (PBCD34) ?8/µL on day 4 of GCSF-based AHSC mobilization as a threshold for plerixafor administration, and compared the efficacy of collection and cost analysis using historical controls. All patients in the study cohort reached their CD34? targets in ?3 collections. Significantly more patients who received plerixafor + GCSF versus GCSF alone reached their CD34? target in one collection (P = 0.045); however, there were no significant differences in the number of collections or in cumulative product yields. The historical cohort had 10.3% mobilization failures; the number of collections per patient needed to reach the target was significantly higher in the historical cohort versus study cohort (P = 0.001) as was the number of patients requiring more than one collection to reach their target (P = 0.023). However, the average cost per patient was also significantly higher in the study cohort (P = 0.025). Further refinement of the algorithm may reduce the difference in cost between the two mobilization strategies. PMID:23426644

Abusin, Ghada A; Abu-Arja, Rolla F; Gingrich, Roger D; Silverman, Margarida D; Zamba, Gideon K D; Schlueter, Annette J

2013-08-01

124

Skip Counting With Counting Collections  

NSDL National Science Digital Library

In this 12-minute video Stephanie Latimer's kindergarten students develop strategies for counting collections of objects. They group objects, skip count, and record their results. The resource includes reflection questions for teacher discussion.

2012-01-01

125

Application of a charge-coupled device photon-counting technique to three-dimensional element analysis of a plant seed (alfalfa) using a full-field x-ray fluorescence imaging microscope  

Microsoft Academic Search

A full-field x-ray fluorescence imaging microscope using a Wolter mirror was constructed at Photon Factory BL3C2. White x rays from a bending magnet were used to excite x-ray fluorescence and to enhance the x-ray fluorescence intensity. A photon-counting method using a charge-coupled device was applied to obtain an x-ray fluorescence spectrum at the image plane. The spatial distributions of some

Masato Hoshino; Toyoaki Ishino; Takashi Namiki; Norimitsu Yamada; Norio Watanabe; Sadao Aoki

2007-01-01

126

Effect of Birth Weight and Maternal Smoking on Cord Blood Leptin Concentrations of Full-Term and Preterm Newborns  

Microsoft Academic Search

Prematurity, maternal smoking, and low birth weight each re- sult in neuroendocrine dysfunction and increased perinatal mor- bidity and mortality. Leptin, an adipocyte-secreted protein, has provided the first physiological link to the regulatory system con- trolling starvation-induced neuroendocrine changes in rodents. This study investigated whether leptin concentrations were de- tectable in cord blood of newborns, and assessed the effect of

CHRISTOS S. MANTZOROS; ANASTASIA VARVARIGOU; VIRGINIA G. KAKLAMANI; NICHOLAS G. BERATIS; JEFFREY S. FLIER

2010-01-01

127

Low body weight gain, low white blood cell count and high serum ferritin as markers of poor nutrition and increased risk for preterm delivery.  

PubMed

This study determined factors of preterm delivery in Taiwan. Healthy women (n=520, age 29.1±4.2 y) at 8-12 weeks of pregnancy were recruited from prenatal clinics. Background information, anthropometrics, biochemical parameters, and dietary intake, collected by 24 h-recall were obtained from the first, second, and third trimesters to delivery. Clinical outcomes of neonates were also collected. The results show that 53.7% of women were primiparous and that the incidence of preterm delivery was 6.2%. Body weight gains in the first trimester and throughout pregnancy were significantly lower in mothers with preterm delivery (preterm group) than in mothers with term delivery (term group, p<0.05). Maternal cholesterol intake, circulating white blood cell counts (WBC) and serum albumin were significantly lower and that serum magnesium and ferritin were significantly higher in the preterm group than in the term group. Maternal weight gain was positively correlated with caloric and nutrient intake (p<0.05). Neonatal birth weight was positively correlated with maternal weight gain and intakes of protein and phosphate during pregnancy; with intakes of calories, vitamin B-1 and B-2 in the first trimester; and with intakes of calcium, magnesium, iron and zinc, as well as circulating WBC in the third trimester. However, neonatal birth weight was negatively correlated with serum iron in the third trimester and with serum iron and ferritin at the time of delivery. In conclusion, maternal weight gain in early pregnancy and WBC, mineral intake and iron status in late pregnancy seem to be major factors affecting delivery and neonatal outcomes. PMID:23353616

Hsu, Wen-Yin; Wu, Cheng-Hsuan; Hsieh, Charles Tsung-Che; Lo, Hui-Chen; Lin, Jen-Shiou; Kao, Mei-Ding

2013-01-01

128

Eosinophil count - absolute  

MedlinePLUS

... on the spot to stop bleeding. In the lab, the blood is placed on a microscope slide. A stain is added to the sample. This causes eosinophils to show up as orange-red granules. The technician then counts how many eosinophils are present per ...

129

Effects of Corynebacterium parvum and BCG therapy on immune parameters in patients with disseminated melanoma a sequential study over 28 days. I. Changes in blood counts, serum immunoglobulins and lymphoid cell populations.  

PubMed Central

The effects of a single immunization of melanoma patients with BCG or C. parvum on the blood counts, serum immunoglobulin levels and lymphoid subpopulations were followed by multiple assays over 28 days. C. parvum produced a decrease in the white cell count, lymphocyte count and lymphoid T and sIg+ cell numbers, which recovered within 1 week; BCG did not produce such a marked depression. Both agents were associated with increases in T cell numbers and lymphocyte PHA blastogenesis after the first week; these declined to pre-immunization values by 3-4 weeks. The sIg-bearing cell subpopulation also increased after BCG. Different methods of expression the results were compared and the difficulties of immunological monitoring are discussed. PMID:428146

Thatcher, N; Swindell, R; Crowther, D

1979-01-01

130

Counting Coins  

NSDL National Science Digital Library

We are learning about money and how to count coins. We need to learn about coins so we can pay for things we need to buy. These activities will help you practice counting money. Remember to record your learning as you work! Coin Paper We have been learning about coins. Listen to the coin song to remember the names of U.S. coins. U.S. Coin Song Before we can count coins, we need to know the names of the different coins and how much each coin is worth. Click the link below to review ...

Thorsen

2012-11-24

131

Reticulocyte count  

MedlinePLUS

... red blood cells being destroyed earlier than normal ( hemolytic anemia ) Bleeding Blood disorder in a fetus or newborn known as erythroblastosis fetalis Kidney disease, with increased production of a hormone called erythropoietin ...

132

Counting carbohydrates  

MedlinePLUS

Carbohydrates are found in fruit, cereal, bread, pasta, and rice. They are quickly turned into a sugar ... sugar better if they can count how many carbohydrates they eat. Your dietitian will teach you a ...

133

Clock Counting  

NSDL National Science Digital Library

Students will practice telling time. Review clock counting with the interactive clock. Now match the clocks. Move over the hour clock to see if you chose correctly. Click the arrows to match the dragon clock to the written time. ...

Mcduffee, Ms.

2008-11-12

134

Choral Counting  

NSDL National Science Digital Library

As a whole group, have students chant the counting sequence starting with one to thirty, using the pointer to follow the number sequence. Over time, increase the range to one to fifty and then one to one hundred. Eventually have a student take over the job of pointing out the numbers in the sequence. Highlight the multiples of ten using a marker or a colored screen and have students chant the counting sequence by 10s. This should be done daily.

Mathematics, Illustrative

2012-07-31

135

The Picture of Inflammation: A New Concept That Combines the White Blood Cell Count and Erythrocyte Sedimentation Rate into a New Hematologic Diagnostic Modality  

Microsoft Academic Search

Background: Physicians who work in small clinics, far away from medical centers, cannot obtain relevant information regarding the acute phase response at low cost and real time. Methods: We adopted a simple slide test and image analysis to determine the number of white blood cells in the peripheral blood, their degree of adhesiveness\\/aggregation as well as that of the red

Rivka Rotstein; Renato Fusman; David Zeltser; Itzhak Shapira; Esther Shabtai; Dani Avitzour; Nicole Sadees; David Levartovsky; Nadir Arber; Amiram Eldor; Shlomo Berliner

2001-01-01

136

Genetic and Functional Analysis of Full-Length Human Immunodeficiency Virus Type 1 env Genes Derived from Brain and Blood of Patients with AIDS  

Microsoft Academic Search

The genetic evolution of human immunodeficiency virus type 1 (HIV-1) in the brain is distinct from that in lymphoid tissues, indicating tissue-specific compartmentalization of the virus. Few primary HIV-1 envelope glycoproteins (Envs) from uncultured brain tissues have been biologically well characterized. In this study, we analyzed 37 full-length env genes from uncultured brain biopsy and blood samples from four patients

Asa Ohagen; Amy Devitt; Kevin J. Kunstman; Paul R. Gorry; Patrick P. Rose; Bette Korber; Joann Taylor; Robert Levy; Robert L. Murphy; Steven M. Wolinsky; Dana Gabuzda

2003-01-01

137

Counting Circles  

NSDL National Science Digital Library

Have students stand and form a circle facing in toward each other. Select a counting sequence to be practiced with no more than 8-10 numbers in the sequence. Have the students start counting around the circle one by one until the last number in the sequence is reached. When the last number is reached all students clap and that student is out and sits down on the floor in the middle of the circle. Start the counting sequence over again until another student reaches the number at the end of the sequence; everyone claps and that student sits in the center with the first student. Continue repeating the sequence until only one child is left standing and the rest are seated in the center of the circle. For example: for the counting sequence 1-10: the first student says "one," the next student says "two" and so on until the 10th students gets to "ten" at this point everyone claps and the tenth child sits in the center of the circle. The eleventh student starts over with "one" and so on.

Mathematics, Illustrative

2012-07-31

138

Counting Coins  

NSDL National Science Digital Library

In this iOS app students practice counting U.S. coins by matching the value, making the total, telling how much, and creating their own values. Students drag coins onto a digital mat or enter values with a keypad to complete the tasks, and then receive feedback.

K12, Inc.

2011-03-23

139

CD41-T-Cell Counts, Spontaneous Apoptosis, and Fas Expression in Peripheral Blood Mononuclear Cells Obtained from Human Immunodeficiency Virus Type 1Infected Subjects  

Microsoft Academic Search

peripheral blood mononuclear cells from subjects with the lowest CD41-cell numbers (0 to 99\\/ml; n 5 20) showed the highest frequency of apoptosis: 22.4% 6 2.7% (mean 6 standard error) versus 13.8% 6 1.2% and 12.7% 6 1.4% among peripheral blood mononuclear cells obtained from patients with 100 to 499 CD41 cells\\/ml (n 5 19) and >500 CD41 cells\\/m l(

ABHAY H. PATKI; DANIEL L. GEORGES; MICHAEL M. LEDERMAN

140

White Blood Cell Count and Incidence of Coronary Heart Disease and Ischemic Stroke and Mortality from Cardiovascular Disease in African American and White Men and Women  

Microsoft Academic Search

) had 1.9 times the risk of incident coronary heart disease (95% confidence interval (CI): 1.19, 3.09), 1.9 times the risk of incident ischemic stroke (95% CI: 1.03, 3.34), and 2.3 times the risk of cardiovascular disease mortality (95% CI: 1.38, 3.72) as their counterparts in the lowest quartile of WBC count (<4,800 cells\\/mm 3 ). These associations were similar

Chong Do Lee; Aaron R. Folsom; F. Javier Nieto; Lloyd E. Chambless; Eyal Shahar; Douglas A. Wolfe

141

Biodiversity Counts  

NSDL National Science Digital Library

This extensive collection of activities from the American Museum of Natural History offers middle school students "an exciting and creative context for involving students in the scientific process while introducing them to the rich diversity and beauty of their local ecosystem." Lesson plans, Web-based interactive activities, useful Web links, profiles of AMNH scientists and staff, and other features help students inventory and analyze the plants and arthropods found in their own neighborhoods. All activities address national science standards, and have been "field tested" in schools around the nation. Biodiversity Counts even has students develop their own exhibitions for their findings -- a great way to build science communication skills.

1998-01-01

142

Counting and language.  

PubMed

(Full text is available at http://www.manu.edu.mk/prilozi). Number words could be considered as a part of general verbal lexicon, although clinical and scientific data suggest that there are specific brain areas that are involved in specific aspects of number and language processing. In this fMRI study we examine the brain response to two number words generation tasks that should be closely related to the process of language generation: counting forward and counting backward. Our results imply that both investigated tasks strongly rely on brain structures usually related to language generation processes with a distinct activation of the prefronatal area for both counting tasks. Furthermore, we found differences in brain response among the investigated tasks regarding activation in the posterior part of the superior temporal gyrus and parietal cortex for the task of counting backward. Those findings suggest that the tasks of counting rely on established language-related brain areas with specific differences depending on cognitive content of the specified task. Key words: fMRI, counting, language generation. PMID:23037186

Sveljo, O; Koprivšek, K; Lu?i?, M; Prvulovi?, N

2012-07-01

143

Genetic and functional analysis of full-length human immunodeficiency virus type 1 env genes derived from brain and blood of patients with AIDS.  

PubMed

The genetic evolution of human immunodeficiency virus type 1 (HIV-1) in the brain is distinct from that in lymphoid tissues, indicating tissue-specific compartmentalization of the virus. Few primary HIV-1 envelope glycoproteins (Envs) from uncultured brain tissues have been biologically well characterized. In this study, we analyzed 37 full-length env genes from uncultured brain biopsy and blood samples from four patients with AIDS. Phylogenetic analysis of intrapatient sequence sets showed distinct clustering of brain relative to blood env sequences. However, no brain-specific signature sequence was identified. Furthermore, there was no significant difference in the number or positions of N-linked glycosylation sites between brain and blood env sequences. The patterns of coreceptor usage were heterogeneous, with no clear distinction between brain and blood env clones. Nine Envs used CCR5 as a coreceptor, one used CXCR4, and two used both CCR5 and CXCR4 in cell-to-cell fusion assays. Eight Envs could also use CCR3, CCR8, GPR15, STRL33, Apj, and/or GPR1, but these coreceptors did not play a major role in virus entry into microglia. Recognition of epitopes by the 2F5, T30, AG10H9, F105, 17b, and C11 monoclonal antibodies varied among env clones, reflecting genetic and conformational heterogeneity. Envs from two patients contained 28 to 32 N-glycosylation sites in gp120, compared to around 25 in lab strains and well-characterized primary isolates. These results suggest that HIV-1 Envs in brain cannot be distinguished from those in blood on the basis of coreceptor usage or the number or positions of N-glycosylation sites, indicating that other properties underlie neurotropism. The study also demonstrates characteristics of primary HIV-1 Envs from uncultured tissues and implies that Env variants that are glycosylated more extensively than lab strains and well-characterized primary isolates should be considered during development of vaccines and neutralizing antibodies. PMID:14581570

Ohagen, Asa; Devitt, Amy; Kunstman, Kevin J; Gorry, Paul R; Rose, Patrick P; Korber, Bette; Taylor, Joann; Levy, Robert; Murphy, Robert L; Wolinsky, Steven M; Gabuzda, Dana

2003-11-01

144

Costs and cost-effectiveness of full implementation of a biennial faecal occult blood test screening program for bowel cancer in Australia  

PubMed Central

Objective To examine the costs and cost-effectiveness of full implementation of biennial bowel cancer screening for Australian residents aged 50–74 years. Design and setting Identification of existing economic models from 1993 to 2010 through searches of PubMed and economic analysis databases, and by seeking expert advice; and additional modelling to determine the costs and cost-effectiveness of full implementation of biennial faecal occult blood test screening for the five million adults in Australia aged 50–74 years. Main outcome measures Estimated number of deaths from bowel cancer prevented, costs, and cost-effectiveness (cost per life-year gained [LYG]) of biennial bowel cancer screening. Results We identified six relevant economic analyses, all of which found colorectal cancer (CRC) screening to be very cost-effective, with costs per LYG under $55 000 per year in 2010 Australian dollars. Based on our additional modelling, we conservatively estimate that full implementation of biennial screening for people aged 50–74 years would have gross costs of $150 million, reduce CRC mortality by 15%–25%, prevent 300–500 deaths from bowel cancer, and save 3600–6000 life-years annually, for an undiscounted cost per LYG of $25 000–$41 667, compared with no screening, and not taking cost savings as a result of treatment into consideration. The additional expenditure required, after accounting for reductions in CRC incidence, savings in CRC treatment costs, and existing ad-hoc colonoscopy use, is likely to be less than $50 million annually. Conclusions Full implementation of biennial faecal occult blood test screening in Australia can reduce bowel cancer mortality, and is an efficient use of health resources that would require modest additional government investment. PMID:21401458

Pignone, Michael P; Flitcroft, Kathy L; Howard, Kirsten; Trevena, Lyndal J; Salkeld, Glenn P; St John, D James B

2011-01-01

145

Viscosity reduction of red blood cells from preterm and full-term neonates and adults in narrow tubes (Fahraeus-Lindqvist effect).  

PubMed

In artificial tubes as well as in blood vessels with diameters less than 500 microns, blood viscosity decreases with decreasing diameter (Fahraeus-Lindqvist effect). Our study measured viscosity of red blood cells (RBC) from 10 preterm infants, 10 term neonates, and 10 adults by means of a capillary viscometer. RBC were suspended in buffer at hematocrits of 0.20, 0.40, and 0.60 1/1 (1.00 1/1 = 100%). Tubes with diameters of 50, 100, and 500 microns were perfused with these suspensions. Viscosity in the 500-microns tubes was not significantly different, at any hematocrit, among the three groups. Viscosity decreased at each of the adjusted hematocrits in the three groups when going from a 500-microns tube to a 50-microns tube. At a hematocrit of 0.60 1/1, viscosity reduction averaged 48 +/- 7% in the preterm infants, 42 +/- 8% in the full-term neonates, and 35 +/- 5% in the adults, whereas the reductions at a hematocrit of 0.20 1/1 were only 32 +/- 6, 27 +/- 4, and 24 +/- 6%, respectively. For the combined data from the neonates and adults, there was a significant inverse relationship of the viscosity in 50-microns tubes at a hematocrit of 0.60 1/1 to the mean corpuscular volume (r = 0.69). To evaluate whether increased membrane elasticity of neonatal RBC contributes to the stronger viscosity reduction of neonatal RBC in narrow tubes, heated neonatal and adult RBC were also studied. The resulting loss of membrane elasticity caused a marked decrease in the viscosity reduction in 50-microns tubes, particularly in the neonates.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:2740150

Zilow, E P; Linderkamp, O

1989-06-01

146

Comparison of venous and capillary differential leukocyte counts using a standard hematology analyzer and a novel microfluidic impedance cytometer.  

PubMed

Capillary blood sampling has been identified as a potentially suitable technique for use in diagnostic testing of the full blood count (FBC) at the point-of-care (POC), for which a recent need has been highlighted. In this study we assess the accuracy of capillary blood counts and evaluate the potential of a miniaturized cytometer developed for POC testing. Differential leukocyte counts in the normal clinical range from fingerprick (capillary) and venous blood samples were measured and compared using a standard hematology analyzer. The accuracy of our novel microfluidic impedance cytometer (MIC) was then tested by comparing same-site measurements to those obtained with the standard analyzer. The concordance between measurements of fingerprick and venous blood samples using the standard hematology analyzer was high, with no clinically relevant differences observed between the mean differential leukocyte counts. Concordance data between the MIC and the standard analyzer on same-site measurements presented significantly lower leukocyte counts determined by the MIC. This systematic undercount was consistent across the measured (normal) concentration range, suggesting that an internal correction factor could be applied. Differential leukocyte counts obtained from fingerprick samples accurately reflect those from venous blood, which confirms the potential of capillary blood sampling for POC testing of the FBC. Furthermore, the MIC device demonstrated here presents a realistic technology for the future development of FBC and related tests for use at the site of patient care. PMID:23028467

Hollis, Veronica S; Holloway, Judith A; Harris, Scott; Spencer, Daniel; van Berkel, Cees; Morgan, Hywel

2012-01-01

147

Effects of Daflon 500 mg* on haemoconcentration and alterations of white blood cell count elicited by the upright position in anaesthetized dogs.  

PubMed

In the passive upright position, arterial and venous pressures in the human feet increase capillary pressure which leads to the filtration of fluid from the circulating plasma into the tissues of the feet. Loss of fluid concentrates both red cells and plasma so that the haematrocrit and plasma protein concentration of venous blood leaving the feet greatly exceed their mean values in the circulation. To study this phenomenon in animals, we used Beagle dogs in upright position. In blood of saphenous vein, red cells, haematocrit and plasma protein concentration have been studied. As in human (Moyses et al. Haemoconcentration and accumulation of white cells in the feet during venous stasis. Int J Microcirc Clin Exp 1987;5:311-20) red cells, haematocrit and plasma protein concentration increase in upright position. The increases in red cells, haematocrit and plasma protein concentration were higher and levels were greater after 2 hours when compared to the corresponding values after 1 hour. Daflon 500 mg, a micronized purified flavonoidic fraction, (200 mg/kg-1 per os) administered 20 minutes before upright position, significantly reduced these increases. This model might be a suitable model to test drugs interfering with venous stasis. PMID:8919260

Delbarre, B; Delbarre, G; Pillion, G; Calinon, F

1995-09-01

148

Avian leucocyte counting using the hemocytometer  

USGS Publications Warehouse

Automated methods for counting leucocytes in avian blood are not available because of the presence of nucleated erythrocytes and thrombocytes. Therefore, total white blood cell counts are performed by hand using a hemocytometer. The Natt and Herrick and the Unopette methods are the most common stain and diluent preparations for this procedure. Replicate hemocytometer counts using these two methods were performed on blood from four birds of different species. Cells present in each square of the hemocytometer were counted. Counting cells in the corner, side, or center hemocytometer squares produced statistically equivalent results; counting four squares per chamber provided a result similar to that obtained by counting nine squares; and the Unopette method was more precise for hemocytometer counting than was the Natt and Herrick method. The Unopette method is easier to learn and perform but is an indirect process, utilizing the differential count from a stained smear. The Natt and Herrick method is a direct total count, but cell identification is more difficult.

Dein, F.J.; Wilson, A.; Fischer, D.; Langenberg, P.

1994-01-01

149

Identification of CSF fistulas by radionuclide counting  

SciTech Connect

A radionuclide counting method, performed with the patient prone and the neck flexed, was used successfully to diagnose CSF rhinorrhea in two patients. A normal radionuclide ratio (radionuclide counts in pledget/radionuclide counts in 1-ml blood sample) was obtained in 11 normal control subjects. Significance was determined to be a ratio greater than 0.37. Use of radionuclide counting method of determining CSF rhinorrhea is recommended when other methods have failed to locate a site of leakage or when posttraumatic meningitis suggests subclinical CSF rhinorrhea.

Yamamoto, Y.; Kunishio, K.; Sunami, N.; Yamamoto, Y.; Satoh, T.; Suga, M.; Asari, S. (Matsuyama Shimin Hospital (Japan))

1990-07-01

150

Differential white cell count by centrifugal microfluidics.  

SciTech Connect

We present a method for counting white blood cells that is uniquely compatible with centrifugation based microfluidics. Blood is deposited on top of one or more layers of density media within a microfluidic disk. Spinning the disk causes the cell populations within whole blood to settle through the media, reaching an equilibrium based on the density of each cell type. Separation and fluorescence measurement of cell types stained with a DNA dye is demonstrated using this technique. The integrated signal from bands of fluorescent microspheres is shown to be proportional to their initial concentration in suspension. Among the current generation of medical diagnostics are devices based on the principle of centrifuging a CD sized disk functionalized with microfluidics. These portable 'lab on a disk' devices are capable of conducting multiple assays directly from a blood sample, embodied by platforms developed by Gyros, Samsung, and Abaxis. [1,2] However, no centrifugal platform to date includes a differential white blood cell count, which is an important metric complimentary to diagnostic assays. Measuring the differential white blood cell count (the relative fraction of granulocytes, lymphocytes, and monocytes) is a standard medical diagnostic technique useful for identifying sepsis, leukemia, AIDS, radiation exposure, and a host of other conditions that affect the immune system. Several methods exist for measuring the relative white blood cell count including flow cytometry, electrical impedance, and visual identification from a stained drop of blood under a microscope. However, none of these methods is easily incorporated into a centrifugal microfluidic diagnostic platform.

Sommer, Gregory Jon; Tentori, Augusto M.; Schaff, Ulrich Y.

2010-07-01

151

WBC (White Blood Cell) Differential Count  

MedlinePLUS

... occur with bacterial infection, leukemia , myelodysplastic disorders, or myeloproliferative neoplasms , for example. Some immature cells that may be ... g., autoimmune disorders , immune deficiency) Leukemia Myelodysplastic syndrome Myeloproliferative neoplasms Some diseases trigger a response by the immune ...

152

Low white blood cell count and cancer  

MedlinePLUS

... blisters. Pain in your stomach area. A very bad headache or one that does not go away. ... pdf/neutropenia.pdf. Accessed July 29, 2013. Managing chemotherapy side effects. Nation Cancer Institute Web site. http:// ...

153

Sequential Changes of Plasma C-Reactive Protein, Erythrocyte Sedimentation Rate and White Blood Cell Count in Spine Surgery : Comparison between Lumbar Open Discectomy and Posterior Lumbar Interbody Fusion  

PubMed Central

Objective C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) are often utilized to evaluate for postoperative infection. Abnormal values may be detected after surgery even in case of non-infection because of muscle injury, transfusion, which disturbed prompt perioperative management. The purpose of this study was to evaluate and compare the perioperative CRP, ESR, and white blood cell (WBC) counts after spine surgery, which was proved to be non-infection. Methods Twenty patients of lumbar open discectomy (LOD) and 20 patients of posterior lumbar interbody fusion (PLIF) were enrolled in this study. Preoperative and postoperative prophylactic antibiotics were administered routinely for 7 days. Blood samples were obtained one day before surgery and postoperative day (POD) 1, POD3, and POD7. Using repeated measures ANOVA, changes in effect measures over time and between groups over time were assessed. All data analysis was conducted using SAS v.9.1. Results Changes in CRP, within treatment groups over time and between treatment groups over time were both statistically significant F(3,120)=5.05, p=0.003 and F(1,39)=7.46, p=0.01, respectively. Most dramatic changes were decreases in the LOD group on POD3 and POD7. Changes in ESR, within treatment groups over time and between treatment groups over time were also found to be statistically significant, F(3,120)=6.67, p=0.0003 and F(1,39)=3.99, p=0.01, respectively. Changes in WBC values also were be statistically significant within groups over time, F(3,120)=40.52, p<0.001, however, no significant difference was found in between groups WBC levels over time, F(1,39)=0.02, p=0.89. Conclusion We found that, dramatic decrease of CRP was detected on POD3 and POD7 in LOD group of non-infection and dramatic increase of ESR on POD3 and POD7 in PLIF group of non-infection. We also assumed that CRP would be more effective and sensitive parameter especially in LOD than PLIF for early detection of infectious complications. Awareness of the typical pattern of CRP, ESR, and WBC may help to evaluate the early postoperative course. PMID:25368764

Choi, Man Kyu; Kim, Kee D; Ament, Jared D.

2014-01-01

154

The Big Pumpkin Count.  

ERIC Educational Resources Information Center

Pumpkin seeds are counted after students convert pumpkins to jack-o-lanterns. Among the activities involved, pupils learn to count by 10s, make estimates, and to construct a visual representation of 1,000. (MP)

Coplestone-Loomis, Lenny

1981-01-01

155

High blood pressure tests (image)  

MedlinePLUS

Routine lab tests are recommended before beginning treatment of high blood pressure to determine organ or tissue damage or other risk factors. These lab tests include urinalysis, blood cell count, ...

156

All about Carbohydrate Counting  

MedlinePLUS

All About Carbohydrate Counting American Diabetes Association? ? 1–800–DIABETES (342–2383)? ? www.diabetes.org ©2009 by the American Diabetes Association, ... much to eat. Toolkit No. 14 What is carbohydrate counting? Carbohydrate counting is a way to plan ...

157

Dropout Count Procedural Handbook.  

ERIC Educational Resources Information Center

This manual outlines the procedure for counting dropouts from the Nevada schools. The State Department of Education instituted a new dropout counting procedure to its student accounting system in January 1988 as part of its response to recommendations of a task force on at-risk youth. The count is taken from each secondary school and includes…

Nevada State Dept. of Education, Carson City. Planning, Research and Evaluation Branch.

158

Clipart ETC: Counting  

NSDL National Science Digital Library

This collection contains over 630 clipart images that can be used for counting. There are Florida-themed flash cards for numbers 0 - 10 offered in English, Spanish, and bilingual options. Illustrations of hands depicting finger counting in both American style (beginning with the index finger) and European style (beginning with the thumb) are available. There are also images of 3-dimensional designs made of cubes and illustrations of bundles of sticks and dominoes for teaching skip-counting, addition, and place value.

Etc, Florida C.

2010-07-19

159

Counting Your Lucky Stars  

NSDL National Science Digital Library

In this activity, learners sample a star field to estimate the number of stars in the universe. This activity simulates how astronomers use sampling instead of census (counting) to more easily collect data in space. Learners predict, count, approximate, and average the number of stars in a Star Field Sheet.

Ricles, Shannon; Hatok, Tim; Taylor, Berlina

2013-01-30

160

Deep Sequencing of HIV-1 near Full-Length Proviral Genomes Identifies High Rates of BF1 Recombinants Including Two Novel Circulating Recombinant Forms (CRF) 70_BF1 and a Disseminating 71_BF1 among Blood Donors in Pernambuco, Brazil  

PubMed Central

Background The findings of frequent circulation of HIV-1 subclade F1 viruses and the scarcity of BF1 recombinant viruses based on pol subgenomic fragment sequencing among blood donors in Pernambuco (PE), Northeast of Brazil, were reported recently. Here, we aimed to determine whether the classification of these strains (n?=?26) extends to the whole genome sequences. Methods Five overlapping amplicons spanning the HIV near full-length genomes (NFLGs) were PCR amplified from peripheral blood mononuclear cells (PBMCs) of 26 blood donors. The amplicons were molecularly bar-coded, pooled, and sequenced by Illumina paired-end protocol. The prevalence of viral variants containing drug resistant mutations (DRMs) was compared between plasma and PBMCs. Results Of the 26 samples studied, 20 NFLGs and 4 partial fragments were de novo assembled into contiguous sequences and successfully subtyped. Two distinct BF1 recombinant profiles designated CRF70_BF1 and CRF71_BF1, with 4 samples in profile I and 11 in profile II were detected and thus constitute two novel recombinant forms circulating in PE. Evidence of dual infections was detected in four patients co-infected with distinct HIV-1 subtypes. According to our estimate, the new CRF71_BF1 accounts for 10% of the HIV-1 circulating strains among blood donors in PE. Discordant data between the plasma and PBMCs-virus were found in 15 of 24 donors. Six of these strains displayed major DRMs only in PBMCs and four of which had detectable DRMs changes at prevalence between 1-20% of the sequenced population. Conclusions The high percentage of the new RF71_BF1 and other BF1 recombinants found among blood donors in Pernambuco, coupled with high rates of transmitted DRMs and dual infections confirm the need for effective surveillance to monitor the prevalence and distribution of HIV variants in a variety of settings in Brazil. PMID:25401747

Pessôa, Rodrigo; Watanabe, Jaqueline Tomoko; Calabria, Paula; Felix, Alvina Clara; Loureiro, Paula; Sabino, Ester C.; Busch, Michael P.; Sanabani, Sabri S.

2014-01-01

161

Shadow Count 2012: Help New York City's Homeless Be Counted!  

E-print Network

! Shadow Count 2012: Help New York City's Homeless Be Counted! Become a Shadow Count Decoy Shadow Count 2013 What: Monday Jan. 28th ­ 29th (overnight), the NYC Department of Homeless Services (DHS) will send hundreds of volunteers all across the city to count NYC's unsheltered homeless people

Qiu, Weigang

162

Shadow Count 2012: Help New York City's Homeless Be Counted!  

E-print Network

! Shadow Count 2012: Help New York City's Homeless Be Counted! Become a Shadow Count Decoy Shadow Count 2012 What: Monday Jan. 30th ­ 31st (overnight), the NYC Department of Homeless Services (DHS) will send hundreds of volunteers all across the city to count NYC's unsheltered homeless people

Qiu, Weigang

163

Great Backyard Bird Count  

NSDL National Science Digital Library

Started in 1998, the Great Backyard Bird Count collects data on wild birds and to display results in near real-time. The event takes place in February in the U.S. and Canada in order to create a snapshot of bird distribution just before the start of spring migration. Participants create accounts and help to count birds for at least 15 minutes on one or more days during the yearly event. Data from past counts can be viewed at the website. A mobile app is available for entering data.

University, Cornell

164

Counting glycans revisited.  

PubMed

We present an algorithm for counting glycan topologies of order [Formula: see text] that improves on previously described algorithms by a factor [Formula: see text] in both time and space. More generally, we provide such an algorithm for counting rooted or unrooted [Formula: see text]-ary trees with labels or masses assigned to the vertices, and we give a "recipe" to estimate the asymptotic growth of the resulting sequences. We provide constants for the asymptotic growth of [Formula: see text]-ary trees and labeled quaternary trees (glycan topologies). Finally, we show how a classical result from enumeration theory can be used to count glycan structures where edges are labeled by bond types. Our method also improves time bounds for counting alkanes. PMID:23974240

Böcker, Sebastian; Wagner, Stephan

2014-10-01

165

Counting Knights and Knaves  

ERIC Educational Resources Information Center

To understand better some of the classic knights and knaves puzzles, we count them. Doing so reveals a surprising connection between puzzles and solutions, and highlights some beautiful combinatorial identities.

Levin,Oscar; Roberts, Gerri M.

2013-01-01

166

HawkCount  

NSDL National Science Digital Library

HawkCount is an online database that facilitates the tracking and reporting of raptor migrations. It includes site reports from hawk-watch sites in Mexico, the United States, and Canada. Materials include an interactive map that provides links to hawk-watch sites; location maps and general information on watch sites; a summary of recent reports; and day and monthly summaries of counts by site.

167

Whose interests count?  

PubMed

Whose interests should count and how should various interests be balanced at the pediatric patient's bedside? The interests of the child patient clearly count. Recently, however, many authors have argued that the family's interests also count. But how should we think about the interests of others? What does it mean to talk about "the family" in this context? Does it really just mean the interests of each individual family member? Or is the family itself a moral entity that has interests of its own independent of the interests of each of its members? Are such interests important only as they affect the patient's interest or also for their own sake? In this special supplement to Pediatrics, a group of pediatricians, philosophers, and lawyers grapple with these questions. They examine these issues from different angles and reach different conclusions. Jointly, they demonstrate the ethical importance and, above all, the ethical complexity of the family's role at the bedside. PMID:25274878

Brudney, Daniel; Lantos, John D

2014-10-01

168

Prime Counting Function Model  

NSDL National Science Digital Library

The Prime Counting Function model uses the trial division algorithm to compute the number of primes less than or equal to the number n. Although the trial division algorithm is inefficient, we use it to perform a lengthy calculation while a standard EJS simulation thread accumulates and plots data from the parallel computation. Users can vary the number of independent threads and observe the computational time. The Prime Counting Function Model was created using the Easy Java Simulations (EJS) modeling tool. It is distributed as a ready-to-run (compiled) Java archive. Double clicking the model's jar file will run the simulation if Java is installed.

Christian, Wolfgang

2013-10-11

169

Blood conservation techniques: where to begin.  

PubMed

Blood conservation techniques are used to reduce the need for allogeneic blood transfusion. One of the most important blood conservation techniques is the optimization of blood counts prior to invasive procedures with anticipated blood loss. Infusion nurses need to understand the importance of treating patients who require the use of parenteral iron to attempt to optimize their blood counts before procedures. Infusion nurses provide a vital link to patient safety and treatment. This article will also discuss other methods of blood conservation frequently used to protect a scarce resource and reduce inappropriate transfusions. PMID:24006113

Stover, John C; Broomer, Bob W

2013-01-01

170

What Counts as Evidence?  

ERIC Educational Resources Information Center

Each disciplinary community has its own criteria for determining what counts as evidence of knowledge in their academic field. The criteria influence the ways that a community's knowledge is created, communicated, and evaluated. Situating reading, writing, and language instruction within the content areas enables teachers to explicitly…

Dougherty Stahl, Katherine A.

2014-01-01

171

"Africa Counts" and Ethnomathematics.  

ERIC Educational Resources Information Center

Discusses the writing of the book "Africa Counts: Number and Pattern in African Culture" and relates efforts to introduce multicultural perspectives into the mathematics curriculum at the elementary and secondary levels. Proposes what needs to be done to introduce ethnomathematical perspectives into the curriculum. (24 references) (MKR)

Zaslavsky, Claudia

1994-01-01

172

Quality Counts Exhibitor Card  

E-print Network

This exhibitor card identifies young livestock exhibitors as participants in the Quality Counts! program. The card is printed with a leather-style background on heavy card stock. It features the 4-H clover and the FFA logo, as well as the logo...

Chilek, Kevin; Gregory, Elizabeth

2004-01-27

173

WY Kids Count.  

ERIC Educational Resources Information Center

This WY Kids Count brochure uses the metaphor of children's building blocks to present information on the current well-being of Wyoming children and to advocate enhancing the lives of young children. Each block (i.e., each develop the brochure) presents concerns in a separate area: (1) poverty, highlighting the number of children living in…

Wyoming Kids Count, Cheyenne.

174

Peripheral circulation in the newborn: Interaction of peripheral blood flow, blood pressure, blood volume, and blood viscosity  

Microsoft Academic Search

Peripheral blood flow and systolic blood pressure (strain-gauge plethysmograph), blood volume (Evans blue) and whole blood viscosity (cone-plate viscometer) have been measured in 66 premature and full-term infants 6 to 144h of age. Blood flow and blood volume were moderately decreased in the infants with respiratory distress. Highly significant (Pr=0.77), blood pressure and blood volume (r=0.50), peripheral resistance and blood

O. Linderkamp; I. Strohhacker; H. T. Versmold; H. Klose; K. P. Riegel; K. Betke

1978-01-01

175

The Watt Count System  

NASA Technical Reports Server (NTRS)

The Watt Count System combines aerospace and computer technology, an engineering systems design approach and the environmental control expertise of a group of engineers who worked on Apollo. First step of the system is a computerized energy consumption analysis based on plans for a new home. Company calculates heating and cooling loads and customizes the most energy efficient system for the particular structure analyzed. A quality control engineer assures that insulation and ducting are installed to specifications. Analysis and design techniques are so accurate that company is able to give homeowner a two-year guarantee that the home's energy consumption will not exceed the kilowatt hour level determined by the computer in step one. In an annual energy performance comparison, a Watt Count home used 45 percent less energy than a conventionally equipped home.

1981-01-01

176

Dinosaur Count and Sort  

NSDL National Science Digital Library

In this activity, learners sort and count different colored plastic dinosaurs by various attributes including tail length, whether or not the dinosaurs have horns, etc. Learners discuss the basis of their sorting, describe individual dinosaurs as well as groups and count the whole as well as subsets of the whole. This identification, sorting and grouping based on different traits (physical attributes, diet, habitat) provides a strong foundation for the development of the concept of species. The lesson plan also explains that dinosaurs lived a long time ago, but because they are no longer alive today, they are said to be extinct. Reasons for their extinction and the concept of endangered species can be explored.

Omsi

2004-01-01

177

Counting process Poisson process  

E-print Network

, 2008 ­ p. 9/1 #12;Compound Poisson Process · Let {N(t)} be a Poisson process with rate · Let Yk(t) = N(t) i=1 Yi · Then {S(t)} is called a compound Poisson process · {S(t)} has stationaryLast Time · Counting process · Poisson process · Equivalent definitions Today's lecture: Sections 6

Ross, Kevin

178

Quality Counts Certificate  

E-print Network

Date Ag Science Teacher / County Extension Agent Be it known that has been trained in the eight core concepts of Quality Counts: Six Pillars of Character Purpose of 4-H/FFA Purpose of Livestock Projects Decision Making and Goal... Setting Livestock Project Impact on Red Meat Industry Responsibility of Producing a Safe Product Medication Usage and Labeling Animal Care and Well-Being Trustworthiness Respect Responsibility Fairness Caring Citizenship 4-H 2?5 11-06 ...

Chilek, Kevin

2007-01-31

179

Count Down for Death  

Microsoft Academic Search

This article is a chronology of the day-by-day life of an inmate in his final week on death row. The procedures designed for this special prisoner—involving, for the warden, unique problems of management—deal with every detail that can possibly be regu lated : counting, feeding, shaving, clothing, mail, visits, preserva tion of good physical condition, etc. The daily schedules present

A. Lamont Smith; Robert M. Carter

1969-01-01

180

Count the Beat  

NSDL National Science Digital Library

This brief article discusses the Count the Beat project, which incorporates music into math instruction. The instructors in this project began each lesson with a brief math exercise followed by a more in-depth music task utilizing number lines, fractions, ratios, and/or probability. While music professionals carried out this project the article does offer some suggestions for application in the math classroom without music professional.

Goulder, Nicky; Lodge, Samantha

2013-01-01

181

Point-of-care, portable microfluidic blood analyzer system  

NASA Astrophysics Data System (ADS)

Recent advances in MEMS technology have provided an opportunity to develop microfluidic devices with enormous potential for portable, point-of-care, low-cost medical diagnostic tools. Hand-held flow cytometers will soon be used in disease diagnosis and monitoring. Despite much interest in miniaturizing commercially available cytometers, they remain costly, bulky, and require expert operation. In this article, we report progress on the development of a battery-powered handheld blood analyzer that will quickly and automatically process a drop of whole human blood by real-time, on-chip magnetic separation of white blood cells (WBCs), fluorescence analysis of labeled WBC subsets, and counting a reproducible fraction of the red blood cells (RBCs) by light scattering. The whole blood (WB) analyzer is composed of a micro-mixer, a special branching/separation system, an optical detection system, and electronic readout circuitry. A droplet of un-processed blood is mixed with the reagents, i.e. magnetic beads and fluorescent stain in the micro-mixer. Valve-less sorting is achieved by magnetic deflection of magnetic microparticle-labeled WBC. LED excitation in combination with an avalanche photodiode (APD) detection system is used for counting fluorescent WBC subsets using several colors of immune-Qdots, while counting a reproducible fraction of red blood cells (RBC) is performed using a laser light scatting measurement with a photodiode. Optimized branching/channel width is achieved using Comsol Multi-Physics™ simulation. To accommodate full portability, all required power supplies (40v, +/-10V, and +3V) are provided via step-up voltage converters from one battery. A simple onboard lock-in amplifier is used to increase the sensitivity/resolution of the pulse counting circuitry.

Maleki, Teimour; Fricke, Todd; Quesenberry, J. T.; Todd, Paul W.; Leary, James F.

2012-03-01

182

Elevated blood pressure among U.S. adults with diabetes, 1988–1994 1 1 The full text of this article is available via AJPM Online at http:\\/\\/www.elsevier.com\\/locate\\/ajpmonline  

Microsoft Academic Search

Background: Recent guidelines and clinical trial results emphasize the importance of controlling blood pressure among people with diabetes. We estimated the prevalence of elevated blood pressure among U.S. adults with diagnosed diabetes, and examined the extent to which elevated blood pressure is being treated and controlled.Methods: The Third National Health and Nutrition Examination Survey (1988–1994), a probability survey of the

Linda S Geiss; Deborah B Rolka; Michael M Engelgau

2002-01-01

183

Counting on and back  

NSDL National Science Digital Library

This interactive Flash applet supports the exploration of numbers to 100 by simulating a 100-bead string. A teacher or child can move all or some beads to the left or right to add and subtract. The controls allow users to move beads individually or 10 at a time to model different counting and calculation strategies. Users can hide or show the numbers represented by the beads. This applet lends itself well to use on an interactive white board. A pdf guide to this collection of teaching applets is cataloged separately.

2006-01-01

184

Skip Count by 5s  

NSDL National Science Digital Library

Help the Third Little Pig skip count to 1,000 bricks in groups of 5. (Note students are not expected to count from 0-1,000 by 5s, but this activity allows them to experience counting within a variety of contexts between 0 and 1,000.)

Hartman, Jayne

2012-07-23

185

Studies of deionization and impedance spectroscopy for blood analyzer  

Microsoft Academic Search

Blood analysis provides vital information for health conditions. For instance, typical infection response is correlated to an elevated White Blood Cell (WBC) count, while low Red Blood Cell (RBC) count, hemoglobin and hematocrit are caused by anemia or internal bleeding. We are developing two essential modules, deionization (DI) chip and microfluidic cytometer with impedance spectroscopy flow, for enabling the realization

Charlotte C. Kwong; Nan Li; Chih-Ming Ho

2005-01-01

186

Blood Clots  

MedlinePLUS

... Groups Advocacy Toolkit Home / For Patients / Blood Disorders Blood Clots Blood clotting, or coagulation, is an important ... of blood and its nutrients. back to top Blood Clots: A Patient's Journey back to top Am ...

187

High background photon counting lidar  

NASA Technical Reports Server (NTRS)

Photon counting with lidar returns is usually limited to low light levels, while wide dynamic range is achieved by counting for long times. The broad emission spectrum of inexpensive high-power semiconductor lasers makes receiver filters pass too much background light for traditional photon counting in daylight. Very high speed photon counting is possible, however, at more than 500 MHz which allows the construction of eyesafe lidar operating in the presence of bright clouds. Detector improvements are possible to count to 20 GHz producing a single shot dynamic range of ten decades.

Lentz, W. J.

1992-01-01

188

Jump on Tens: Counting Fun  

NSDL National Science Digital Library

Learners combine counting, multiples, and number patterns with jumping up and down. To start, pick a counting number. Young learners count by 1âs or 2âs; older children by 5âs or 10âs; for more challenge, learners count by 3âs, 7âs, or 2.5âs. Everyone takes turns saying the next number in the counting sequence and jumps whenever anyone says a number ending in 0. Try adding extra actions: clap your hands on a number with a â4â in it, or hop on each odd number. Available as a web page and downloadable pdf.

Terc

2010-01-01

189

Enhancing the performance of a point-of-care CD4+ T-cell counting microchip through monocyte depletion for HIV/AIDS diagnostics  

PubMed Central

CD4+ T cell counts are important tests used to stage HIV-postive patients, enabling clinicians to make informed antiretroviral treatment decisions and to monitor the therapeutic outcomes. However, state-of-the-art CD4 counting methods based on flow cytometry are not applicable in resource-limited settings, due to their high cost and technical requirements. In previous work, we reported the development of a cell isolation microchip that can be used at the point of care for CD4 counts. In that microfluidic chip, CD4+ T cells were separated from 10 ?L of whole blood, and enumerated via either light microscopy or impedance sensing. The microchip counts matched flow cytometry results in the intermediate CD4 count range, between 200–800 cells/?L, but displayed a positive bias at absolute CD4 counts below 200 cells/?L, due largely to monocyte contamination. To enhance the performance in the low CD4 count range, we report here an improved design of a two-stage microfluidic device to deplete monocytes from whole blood, followed by CD4+ T cell capture. Using the double-stage device combined with a high viscosity rinsing solution, we obtained microchip CD4 counts comparable to flow cytometry results in the full clinically relevant range. In addition to CD4 counting, the strategy of contaminant depletion prior to target cell isolation can be easily adapted to immunoaffinity capture of other cell types that lack a unique surface marker from a complex biological fluid. PMID:19417901

Cheng, Xuanhong; Gupta, Amit; Chen, Chihchen; Tompkins, Ronald G.; Rodriguez, William; Toner, Mehmet

2014-01-01

190

Blood basophils in lung cancer.  

PubMed Central

Peripheral-blood basophils were counted, in thick smears, in samples from patients with primary bronchial carcinoma, from patients in the same wards and from normal individuals. The median counts for patients with other chest conditions (15.5/microliter) and bronchial-carcinoma patients free of tumour months to years after resection (16/microliter) did not differ from those for normal individuals (19/microliter), but tumour-bearers showed higher counts (median 33/microliter), 24/41 having counts above the highest count in normal individuals (29/microliter): P less than 0.002). The highest values were in patients with squamous bronchial carcinoma, apparently reflecting spontaneous challenge of an anti-tumour immune response. In those tested at the time of diagnosis, higher values in both lymphocyte and basophil counts were related to surgical resectability. PMID:7059471

Anthony, H. M.

1982-01-01

191

Effect of extracorporeal ultraviolet blood irradiation on blood cholesterol level  

NASA Astrophysics Data System (ADS)

We have studied the effect of extracorporeal ultraviolet blood irradiation on cholesterol metabolism in patients with cardiovascular diseases. We have carried out a comprehensive analysis of the spectral characteristics of blood and plasma, gas-exchange and oximetry parameters, and the results of a complete blood count and chemistry panel before and after UV blood irradiation. We have assessed the changes in concentrations of cholesterols (total cholesterol, low-density lipoprotein (LDL) cholesterol, triglycerides) in the blood of the patients in response to a five-day course of UV blood irradiation. The changes in the spectral characteristics of blood and plasma, the chemistry panel, the gas composition, and the fractional hemoglobin composition initiated by absorption of UV radiation are used to discuss the molecular mechanisms for the effect of therapeutic doses of UV radiation on blood cholesterols.

Zalesskaya, G. A.; Laskina, O. V.; Mitkovskaya, N. P.; Kirkovsky, V. V.

2012-07-01

192

Kids Count Alaska Data Book, 2002.  

ERIC Educational Resources Information Center

This Kids Count Data Book examines statewide trends in the well-being of Alaska's children. The statistical portrait is based on key indicators in six areas: (1) infancy, including prenatal care, low birth weight, and infant mortality; (2) economic well-being, including child poverty, children with no parent working full-time, children in single…

Leask, Linda, Ed.

193

Kids Count Alaska Data Book, 2001.  

ERIC Educational Resources Information Center

This Kids Count Data Book examines statewide trends in the well-being of Alaska's children. The statistical portrait is based on key indicators in six areas: (1) infancy, including prenatal care, low birth weight, and infant mortality; (2) economic well-being, including child poverty, children with no parent working full-time, and teen births; (3)…

Leask, Linda, Ed.

194

Kids Count Alaska, 2000 Data Book.  

ERIC Educational Resources Information Center

This Kids Count Data Book examines statewide trends in the well-being of Alaska's children. The statistical portrait is based on key indicators in six areas: (1) infancy, including prenatal care, low birth weight, and infant mortality; (2) economic well-being, including child poverty, children with no parent working full-time, and teen births; (3)…

Leask, Linda, Ed.

195

Making kids count.  

PubMed

Using data from the 1988 KIDS COUNT Data Book, compiled and published by The Annie E. Casey Foundation, the most recent state figures (1995) are compared with corresponding data from 1985 to assess the trends in child well-being in each state during the decade. The 10 key indicators used are taken from governmental data sources and reflect the best data available for each of the measures. Between 1985 and 1995, child well-being worsened across the country in five of the indicators, i.e., percent of low birthweight babies; rate of teen deaths by accident, homicide and suicide; teen birth rate; Juvenile Violent Crime Arrest Rate; and percent of families with children headed by a single parent. Areas of improvement include: infant mortality; child death rate; percent of teens who are high school dropouts; and percent of teens not attending school and/or not working. There was no change between 1985 and 1995 in the percent of children living in poverty. When the states are ranked by a composite of the 10 indicators of childhood well-being, a cluster of states in the South and Southwest are at or near the bottom of the rankings while the New England states and those in the upper plains are typically near the top. The states near the top have higher incomes and lower poverty rates than those near the bottom. PMID:9691356

O'Hare, W P

1998-01-01

196

Compton suppression gamma-counting: The effect of count rate  

USGS Publications Warehouse

Past research has shown that anti-coincidence shielded Ge(Li) spectrometers enhanced the signal-to-background ratios for gamma-photopeaks, which are situated on high Compton backgrounds. Ordinarily, an anti- or non-coincidence spectrum (A) and a coincidence spectrum (C) are collected simultaneously with these systems. To be useful in neutron activation analysis (NAA), the fractions of the photopeak counts routed to the two spectra must be constant from sample to sample to variations must be corrected quantitatively. Most Compton suppression counting has been done at low count rate, but in NAA applications, count rates may be much higher. To operate over the wider dynamic range, the effect of count rate on the ratio of the photopeak counts in the two spectra (A/C) was studied. It was found that as the count rate increases, A/C decreases for gammas not coincident with other gammas from the same decay. For gammas coincident with other gammas, A/C increases to a maximum and then decreases. These results suggest that calibration curves are required to correct photopeak areas so quantitative data can be obtained at higher count rates. ?? 1984.

Millard, H.T., Jr.

1984-01-01

197

Kids Count [and] Families Count in Delaware: Fact Book, 1998.  

ERIC Educational Resources Information Center

This Kids Count report is combined with Families Count, and provides information on statewide trends affecting children and families in Delaware. The first statistical profile is based on 10 main indicators of child well-being: (1) births to teens; (2) low birth weight babies; (3) infant mortality; (4) child deaths; (5) teen deaths; (6) juvenile…

Nelson, Carl, Ed.; Wilson, Nancy, Ed.

198

Blood Transfusion  

MedlinePLUS

... from the NHLBI on Twitter. What Is a Blood Transfusion? A blood transfusion is a safe, common ... Very rarely, serious problems develop. Important Information About Blood The heart pumps blood through a network of ...

199

Blood Transfusions  

MedlinePLUS

... United States get blood transfusions. A Bit About Blood Blood is like the body's transportation system, busy ... his or her body. Continue What Is a Blood Transfusion? A transfusion is a relatively simple medical ...

200

Blood Thinners  

MedlinePLUS

If you have some kinds of heart or blood vessel disease, or if you have poor blood flow to your brain, your doctor may recommend that you take a blood thinner. Blood thinners reduce the risk of heart ...

201

Blood culture  

MedlinePLUS

Culture - blood ... A blood sample is needed. The site where blood will be drawn is first cleaned with an antiseptic such ... organism from the skin getting into (contaminating) the blood sample and causing a false-positive result (see ...

202

Blood Types  

MedlinePLUS

... the blood cells as belonging in our own system. Blood cell markers are microscopic. But they can make the difference between blood being accepted or rejected after a transfusion. So medical experts group blood into types based on the different ...

203

Counting on Technology.  

ERIC Educational Resources Information Center

Presents data from 44 library/information science programs in the United States. Ten tables show status of 1996 graduates; placements/full-time salaries by region; full-time salaries of traditional versus nontraditional graduates; placements by organization; special placements; placements/full-time salaries of graduates; salaries of minorities by…

Carson, C. Herbert

1997-01-01

204

women 92 48 7 STAFF COUNTS SUMMARY  

E-print Network

women 92 48 7 STAFF COUNTS SUMMARY Full-Time Staff - Durham & UNHM - Fall 2009 Total 1751 % men 774 44.2 women 977 55.8 non-resident alien 7 0.4 Minority Staff - Full-Time - Durham & UNHM - Fall 2009 % Total 66 3.8 (of total) men 30 45.5 women 36 54.5 native am/alaskan 4 6.1 black, non-hispanic 19 28

New Hampshire, University of

205

Preschooler's Counting in Peer Interaction.  

ERIC Educational Resources Information Center

For this experiment, part of a larger study on preschoolers' counting competence, 3-, 4-, and 5-year-olds played a counting game with their peers after becoming familiar with the game during structured interviews with an adult. It was expected that the symmetrical nature of peer interaction would allow children to display quantitative knowledge in…

Curtis, Reagan P.

206

Illegal aliens and census counts  

Microsoft Academic Search

Should illegal aliens be excluded from 1990 census counts? We begin a consideration of this question by examining the demographic, economic, and social contexts within which the question of including or excluding illegal aliens from census counts has arisen, especially in the case of the 1980 census. This is important because arguments for exclusion have often been based in part

Frank D. Bean; Rodolfo O. de la Garza

1988-01-01

207

Sharing Strategies for Counting Collections  

NSDL National Science Digital Library

In this 8-minute video Laretha Todd's third grade students develop efficient strategies for counting collections of objects. They group objects, skip count, and then record their results. The resource includes a transcript of the lesson (doc) and reflection questions for teacher discussion.

2012-01-01

208

KIDS COUNT Pocket Guide, 2005  

ERIC Educational Resources Information Center

By providing policymakers and citizens with benchmarks of child well-being, KIDS COUNT seeks to enrich local, state, and national discussions concerning ways to secure better futures for all children. This "Pocket Guide" is derived from the 2005 "KIDS COUNT Data Book." The following sections are included: (1) Essay; (2) Charts on 10 Key…

Annie E. Casey Foundation, 2005

2005-01-01

209

Hanford whole body counting manual  

SciTech Connect

This document, a reprint of the Whole Body Counting Manual, was compiled to train personnel, document operation procedures, and outline quality assurance procedures. The current manual contains information on: the location, availability, and scope of services of Hanford's whole body counting facilities; the administrative aspect of the whole body counting operation; Hanford's whole body counting facilities; the step-by-step procedure involved in the different types of in vivo measurements; the detectors, preamplifiers and amplifiers, and spectroscopy equipment; the quality assurance aspect of equipment calibration and recordkeeping; data processing, record storage, results verification, report preparation, count summaries, and unit cost accounting; and the topics of minimum detectable amount and measurement accuracy and precision. 12 refs., 13 tabs.

Palmer, H.E.; Brim, C.P.; Rieksts, G.A.; Rhoads, M.C.

1987-05-01

210

How to Scan Blood Smears, Identify, and Count Parasites  

E-print Network

of oil can be removed from the edge of the slide with a kimwipe, and the slide replaced into its normal. For Plasmodium, male gametocytes (microgametocytes) typically stain faintly and the cell looks pale or pink (macrogametocytes) stain blue, sometimes dark blue and the nucleus is more compact. The distribution of the malaria

Schall, Joseph J.

211

QUANTIFICATION OF HEMATOZOA IN BLOOD SMEARS  

Microsoft Academic Search

Ten thin blood smears from mourning doves (Zenaida macroura) infected with Haemoproteus maccallumi were examined by each of two observers using identical techniques and microscopy in an attempt to delineate the factors necessary to provide an accurate estimate of the number of parasites\\/n erythrocytes. The number of erythrocytes examined must be actually counted, not estimated from extrapolated partial counts or

Ralph D. Godfrey; Alan M. Fedynich; Danny B. Pence

1987-01-01

212

Count the Dots: Binary Numbers  

NSDL National Science Digital Library

Data in computers is stored and transmitted as a series of zeros and ones. Learners explore how to represent numbers using just these two symbols, through a binary system of cards. When the card's dots are showing, its value is 1 and the dots are counted. When the card's dots are not showing, its value is 0 and the dots are not counted. Learners model binary counting to discover patterns and represent numbers. This activity includes three worksheet activities (1 introductory and 2 extensions) for learners to complete and background information for the instructor.

Technology, National C.

2012-12-13

213

Every Week Counts  

PubMed Central

In this column, the editor of The Journal of Perinatal Education discusses implications for reducing the incidence of nonmedically indicated deliveries before full-term. The editor also describes the contents of this issue, which offer a broad range of resources, research, and inspiration for childbirth educators in their efforts to promote, support, and protect natural, safe, and healthy birth.

Budin, Wendy C.; Budin, Wendy C.

2013-01-01

214

Counting Triangles to Sum Squares  

ERIC Educational Resources Information Center

Counting complete subgraphs of three vertices in complete graphs, yields combinatorial arguments for identities for sums of squares of integers, odd integers, even integers and sums of the triangular numbers.

DeMaio, Joe

2012-01-01

215

Counting Graylings on the Tundra  

NSDL National Science Digital Library

This article profiles Linda Deegan, scientist with the Arctic Long-Term Ecological Research site in the Kuparuk River region of Alaska, as she counts and tags Arctic grayling as they migrate from streams to lakes in the fall.

Landis, Carol

216

Applying Counting Techniques Shelly Smith  

E-print Network

Applying Counting Techniques To Sudoku Shelly Smith 7 4 5 4 8 3 4 1 9 4 8 2 7 3 4 1 1 5 1 5 1 1 1 1 3 8 8 79 5 3 June 15, 2009 Shelly Smith Applying Counting TechniquesTo Sudoku #12;How many ways...? How many ways can we put the integers 1 through 5 in the spaces below if order matters? Shelly Smith

Tefera, Akalu

217

Immunoelectrophoresis - blood  

MedlinePLUS

IEP - serum; Immunoglobulin electrophoresis - blood; Gamma globulin electrophoresis; Serum immunoglobulin electrophoresis ... A blood sample is needed. For information on how this is done, see: Venipuncture

218

Standardization of 241Am by digital coincidence counting, liquid scintillation counting and defined solid angle counting.  

PubMed

The nuclide (241)Am decays by alpha emission to (237)Np. Most of the decays (84.6%) populate the excited level of (237)Np with energy of 59.54 keV. Digital coincidence counting was applied to standardize a solution of (241)Am by alpha-gamma coincidence counting with efficiency extrapolation. Electronic discrimination was implemented with a pressurized proportional counter and the results were compared with two other independent techniques: Liquid scintillation counting using the logical sum of double coincidences in a TDCR array and defined solid angle counting taking into account activity inhomogeneity in the active deposit. The results show consistency between the three methods within a limit of a 0.3%. An ampoule of this solution will be sent to the International Reference System (SIR) during 2009. Uncertainties were analysed and compared in detail for the three applied methods. PMID:20031433

Balpardo, C; Capoulat, M E; Rodrigues, D; Arenillas, P

2010-01-01

219

Sampling Site Matters When Counting Lymphocyte Subpopulations  

PubMed Central

Clinical and scientific work routinely relies on antecubital venipunctures for hematological, immunological or other analyses on blood. This study tested the hypothesis that antecubital veins can be considered to be a good proxy for other sampling sites. Using a hematocytometer and a flow cytometer, we analyzed the cell counts from samples coming from the radial artery, the dorsal hand veins and the antecubital veins from 18 volunteers. Most surprisingly, we identified the greatest difference not to exist between arterial and venous circulation, but between the distal (radial artery & dorsal hand veins) and proximal (antecubital veins) sampling sites. Naïve T cells had a higher cell count distally compared to proximally and the reverse was true for effector memory T cells. Despite these differences there were high correlations between the different sampling sites, which partially supports our initial hypothesis. Our findings are crucial for the future design and interpretation of immunological research, and for clinical practice. Furthermore, our results suggest a role for interval lymph nodes in the trafficking of lymphocytes. PMID:22848485

Ogunjimi, Benson; Peeters, Dieter; Hens, Niel; Malfait, Ronald; Van Tendeloo, Viggo; Van Damme, Pierre

2012-01-01

220

Hanford whole body counting manual  

SciTech Connect

This document describes the Hanford Whole Body Counting Program as it is administered by Pacific Northwest Laboratory (PNL) in support of the US Department of Energy--Richland Operations Office (DOE-RL) and its Hanford contractors. Program services include providing in vivo measurements of internally deposited radioactivity in Hanford employees (or visitors). Specific chapters of this manual deal with the following subjects: program operational charter, authority, administration, and practices, including interpreting applicable DOE Orders, regulations, and guidance into criteria for in vivo measurement frequency, etc., for the plant-wide whole body counting services; state-of-the-art facilities and equipment used to provide the best in vivo measurement results possible for the approximately 11,000 measurements made annually; procedures for performing the various in vivo measurements at the Whole Body Counter (WBC) and related facilities including whole body counts; operation and maintenance of counting equipment, quality assurance provisions of the program, WBC data processing functions, statistical aspects of in vivo measurements, and whole body counting records and associated guidance documents. 16 refs., 48 figs., 22 tabs.

Palmer, H.E.; Rieksts, G.A.; Lynch, T.P.

1990-06-01

221

Kentucky Kids Count 2001 County Data Book: Families Count.  

ERIC Educational Resources Information Center

This Kids Count county data book is the eleventh in a series to measure the well-being of Kentucky's children and focuses on the vital role that families play in ensuring their children's success. Included at the beginning of this document is an executive summary of the databook providing an overview of the statewide data for six child and family…

Salley, Valerie

222

Counting Out Loud Counting Objects Give-A-Number Identification  

E-print Network

Education Less than H.S. diploma H.S. diploma / G.E.D. Technical / Trade school Some college College degree Post-college education No response 56% 24% 4% 8% 1% 7% 16% 69% 15% Counting Out Loud Introduction

Stanford, Kyle

223

Wiskids Count Data Book, 2003.  

ERIC Educational Resources Information Center

This WisKids Count data book provides a statistical portrait of the well-being of Wisconsin's children. In addition to demographic data indicating changing communities, the indicators and data are organized into five overarching goals: (1) Healthy Families and Children Thrive, including births to single women, infant deaths, and health care…

Cranley, M. Martha; Bianchi, J. P.; Eleson, Charity; Hall, Linda; Jacobson, Bob; Jackson, Kristin; Peacock, Jon

224

Mathline Activity I -- Borda Count  

NSDL National Science Digital Library

Mock-election demonstrating the Borda Electoral Count, a ranking system of elections that is rarely used for governmental elections, but often used to rank in non-governmental settings such as student governments or college sports teams. This activity is especially useful when used in conjunction with other electoral simulations.

2000-01-01

225

On Counting the Rational Numbers  

ERIC Educational Resources Information Center

In this study, we show how to construct a function from the set N of natural numbers that explicitly counts the set Q[superscript +] of all positive rational numbers using a very intuitive approach. The function has the appeal of Cantor's function and it has the advantage that any high school student can understand the main idea at a glance…

Almada, Carlos

2010-01-01

226

Oklahoma Kids Count Factbook, 1995.  

ERIC Educational Resources Information Center

This Kids Count report details county and statewide trends in the well-being of Oklahoma's children. The statistical report is based on eight indicators of child well being: (1) percent low birthweight infants; (2) infant mortality rate; (3) births to unmarried teens; (4) child abuse and neglect rates; (5) child death rate; (6) children living in…

Oklahoma Inst. for Child Advocacy, Inc., Oklahoma City. Oklahoma Kids Count.

227

Counting Bitangents with Stable Maps  

E-print Network

This paper is an elementary introduction to the theory of moduli spaces of curves and maps. As an application to enumerative geometry, we show how to count the number of bitangent lines to a projective plane curve of degree $d$ by doing intersection theory on moduli spaces.

David Ayala; Renzo Cavalieri

2005-05-09

228

Kids Count in Colorado! 2003.  

ERIC Educational Resources Information Center

This Kids Count report examines state, county, and regional trends in the well-being of Colorado's children. The first part of the report is presented in four chapters. Chapter 1 includes findings regarding the increasing diversity of the child population, linguistic isolation, the impact of parental unemployment, child poverty, and the affordable…

Boeke, Kaye

229

South Carolina Kids Count, 2000.  

ERIC Educational Resources Information Center

This Kids Count report examines statewide trends in the well-being of South Carolina's children. The statistical portrait is based on 41 indicators in the areas of demographics, family, economic status, health, readiness and early school performance, scholastic achievement, and adolescent risk behaviors. The indicators are: (1) population; (2)…

Holmes, A. Baron

230

KIDS COUNT New Hampshire, 2000.  

ERIC Educational Resources Information Center

This Kids Count report presents statewide trends in the well-being of New Hampshire's children. The statistical report is based on 22 indicators of child well-being in 5 interrelated areas: (1) children and families (including child population, births, children living with single parent, and children experiencing parental divorce); (2) economic…

Shemitz, Elllen, Ed.

231

Oklahoma Kids Count Factbook '98.  

ERIC Educational Resources Information Center

This Kids Count report details county and statewide trends in the well-being of Oklahoma's children. The statistical portrait is based on eight indicators of child well-being: (1) low birthweight infants; (2) infant mortality; (3) births to teens; (4) child abuse and neglect; (5) child death; (6) child poverty; (7) high school dropouts; and (8)…

Oklahoma Inst. for Child Advocacy, Inc., Oklahoma City. Oklahoma Kids Count.

232

Oklahoma Kids Count Factbook, 2002.  

ERIC Educational Resources Information Center

This Kids Count Factbook details county and statewide trends in the well-being of children in Oklahoma. The statistical portrait is based on seven indicators or benchmarks of child well-being: (1) low birthweight infants; (2) infant mortality; (3) births to young teens; (4) child abuse and neglect; (5) child and teen death; (6) high school…

Ingraham, Sandy

233

Oklahoma Kids Count Factbook, 2001.  

ERIC Educational Resources Information Center

This Kids Count Factbook details county and statewide trends in the well-being of Oklahoma's children. The statistical portrait is based on seven indicators or benchmarks of child well-being: (1) low birth weight infants; (2) infant mortality; (3) births to young teens; (4) child abuse and neglect; (5) child and teen death; (6) high school…

Ingraham, Sandy

234

Oklahoma Kids Count Factbook '97.  

ERIC Educational Resources Information Center

This Kids Count report details county and statewide trends in the well-being of Oklahoma's children. The statistical report is based on eight indicators of child well being: (1) economic distress; (2) percent low birthweight infants; (3) infant mortality rate; (4) births to teens; (5) child abuse and neglect rates; (6) child and teen death rate;…

Oklahoma Inst. for Child Advocacy, Inc., Oklahoma City. Oklahoma Kids Count.

235

South Carolina Kids Count, 2001.  

ERIC Educational Resources Information Center

This Kids Count report examines statewide trends in the well-being of South Carolina's children. The statistical portrait is based on 42 indicators in the areas of demographics, family, economic status, health, readiness and early school performance, scholastic achievement, and adolescent risk behaviors. The indicators are: (1) population; (2)…

Holmes, A. Baron

236

Oklahoma Kids Count Factbook, 1999.  

ERIC Educational Resources Information Center

This Kids Count Factbook details county and statewide trends in the well-being of Oklahoma's children. The statistical portrait is based on eight indicators of child well-being: (1) low birth weight infants; (2) infant mortality; (3) births to young teens; (4) child abuse and neglect; (5) child and teen death; (6) child poverty; (7) high school…

Ingraham, Sandy

237

Maryland Kids Count Factbook, 2001.  

ERIC Educational Resources Information Center

This 7th annual Kids Count Factbook provides information on trends in the well-being of children in Maryland and its 24 jurisdictions. The statistical portrait is based on 18 indicators of well-being: (1) low birth-weight infants; (2) infant mortality; (3) early prenatal care; (4) binge drinking; (5) child deaths; (6) child injury rate; (7) grade…

Advocates for Children and Youth, Baltimore, MD.

238

Oklahoma Kids Count Factbook '96.  

ERIC Educational Resources Information Center

This data book presents findings of the Kids Count Project on current conditions faced by Oklahoma children age birth through 18. This second annual factbook organizes state and county data over a period of time to enable conditions for children in each county to be compared and ranked. The benchmark indicators studied include low birthweight…

Ingraham, Sandy

239

Maryland KIDS COUNT Factbook, 1999.  

ERIC Educational Resources Information Center

This Kids Count factbook is the fifth to examine statewide and county trends in the well-being of Maryland's children. The statistical portrait is based on indicators in the domains of economic well-being, good health, safety, and preparing for adulthood. The 16 indicators are: (1) child poverty; (2) child support; (3) births to teens; (4) low…

Advocates for Children and Youth, Baltimore, MD.

240

KIDS COUNT Data Brief, 2009  

ERIC Educational Resources Information Center

This 2009 KIDS COUNT Data Brief features highlights of the enhanced, mobile-friendly Data Center; data on the 10 key indicators of child well-being for all U.S. states, the District of Columbia, and many cities, counties, and school districts; and a summary of this year's essay, which calls for improvements to the nation's ability to design and…

Annie E. Casey Foundation, 2009

2009-01-01

241

Wyoming Kids Count Factbook, 1997.  

ERIC Educational Resources Information Center

This Kids Count factbook details statewide trends in the well-being of Wyoming's children. The 1997 report has been expanded to include detailed information on the status of children by categories of welfare, health, and education. The first part of the factbook documents trends by county for 15 indicators: (1) poverty and population; (2)…

Wyoming Kids Count, Cheyenne.

242

Kids Count Data Sheet, 2000.  

ERIC Educational Resources Information Center

Data from the 50 United States are listed for 1997 from Kids Count in an effort to track state-by-state the status of children in the United States and to secure better futures for all children. Data include percent low birth weight babies; infant mortality rate; child death rate; rate of teen deaths by accident, homicide, and suicide; teen birth…

Annie E. Casey Foundation, Baltimore, MD.

243

Impact of JAK2 V617F Mutation on Hemogram Variation in Patients with Non-Reactive Elevated Platelet Counts  

PubMed Central

Background Non-reactive platelet counts elevation occurs mainly in myeloproliferative disorders (MPDs), which have been reported to be closely associated with JAK2 V617F mutation. Complete blood cell count (CBC) is essential in diagnosis of MPDs, however, the impact of JAK2 V617F mutation on the patients’ hemogram variation remains not clear. Methods JAK2 V617F mutation was detected by allele specific real-time quantitative fluorescence PCR (AS-qPCR). Results Of the 402 non-reactive platelet elevating patients, JAK2 V617F mutation was detected in 222 (55.2%) patients. RBC counts, WBC counts, platelet-large contrast ratio (P-LCR), platelet distribution width (PDW) and mean platelet volume (MPV) were much higher in JAK2 V617F mutated patients, except platelet counts. In addition, when the patients were classified into subgroups by blood cell counts, it was found that JAK2 V617F mutation rate increased progressively with the increase of RBC counts and WBC counts, other than platelet counts. Furthermore, trilineage hyperplasia group showed highest JAK2 V617F mutation rate (93.26%), followed by the bilineage hyperplasia groups. Lastly, JAK2 V617F mutant allele burden was found much higher in polycythemia vera (PV) patients [median(P25–P75): 45.02%(35.12%–54.22%)] than in essential thrombocythemia (ET) patients [median(P25–P75): 28.23%(17.77%–41.66%)], and that it increased with WBC counts (r?=?0.393, p?=?0.000) and RBC counts(r?=?0.215, p?=?0.001), other than platelet counts (r?=??0.051, p?=?0.452). Further analysis revealed that in ET patients, JAK2 V617F mutant allele burden correlated with WBC counts and platelet counts positively, other than RBC counts, while in PV patients, it correlated with WBC counts and RBC counts positively, but not platelet counts. Conclusions JAK2 V617F mutation occurs frequently in patients with non-reactive elevated platelet counts. The presence of JAK2 V617F mutation has great impact on hemogram variation, including RBC counts, WBC counts, platelet parameters and lineage hyperplasia, but not on platelet counts. Besides, JAK2 V617F mutant allele burden affects the blood cell proliferation pattern. PMID:23469088

Zhou, Juan; Ye, Yuanxin; Zeng, Shugen; Zhou, Yi; Mao, Zhigang; Song, Xingbo; Ying, Binwu; Lu, Xiaojun; Jiang, Hong; Wang, Lanlan

2013-01-01

244

Counting  

NSDL National Science Digital Library

This interactive Flash applet supports the exploration of early number. A child or teacher can place a number of objects on the screen and then move the objects to group them, drag them onto a number line or track, into a hoop to create sets of objects, or into a 10 by 10 grid. This applet lends itself well to group work with a projector. Clicking on the info button allows the user to mouse over items to learn how to use them.

2011-01-01

245

Counting \\  

Microsoft Academic Search

In David Foster Wallace’s fiction, the salient topic is the cultivation of moral personhood. Personhood and human individuality are represented through descriptive categories like “citizenship,” “wholeness,” “authenticity,” or “spirituality,” all nominations that bristle against the “postmodern” genre in which his fiction is critically located—and all partially inadequate in capturing Wallace’s spirit comprehensively. In Wallace’s fiction personhood is constantly frustrated by

Charles J. Thaxton

2012-01-01

246

What's Blood?  

MedlinePLUS

... want anymore. Nutrients, hormones, proteins, and waste are dissolved in the plasma — kind of like the cocoa ... healthy blood, the body won't get the oxygen and energy it needs. Healthy blood also protects ...

247

Donating Blood  

MedlinePLUS

... How to Manage a Serious Allergic Reaction Quiz: Baseball Injuries Donating Blood KidsHealth > Teens > Body > Health Basics > ... who donate blood notice a few minor side effects like nausea, lightheadedness, dizziness, or fainting, but these ...

248

Haematological and blood chemical values from Bothrops ammodytoides (ophidia-crotalidae) in captivity  

Microsoft Academic Search

In order to establish reference haematological and blood chemistry parameters, blood samples were obtained from 50 healthy\\u000a specimens ofBothrops ammodytoides kept in captivity. The haematological parameters determined were: red blood cell count (RBC); total leucocyte (WBC) and differential\\u000a leucocyte cell count; thrombocyte count; haematocrit (PCV); haemoglobin concentration; mean corpuscular volume (MCV); mean\\u000a corpuscular haemoglobin (MCH) and mean corpuscular haemoglobin concentration

J. C. Troiano; J. C. Vidal; E. F. Gould; G. Malinskas; J. Gould; M. Scaglione; L. Scaglione; J. J. Heker; C. Simoncini; H. Dinápoli

1999-01-01

249

Quantification of hematozoa in blood smears.  

PubMed

Ten thin blood smears from mourning doves (Zenaida macroura) infected with Haemoproteus maccallumi were examined by each of two observers using identical techniques and microscopy in an attempt to delineate the factors necessary to provide an accurate estimate of the number of parasites/n erythrocytes. The number of erythrocytes examined must be actually counted, not estimated from extrapolated partial counts or from the number of fields of view examined. Doubling the number of erythrocytes counted (1) decreased the overdispersed frequency distribution patterns in only 25% of the replicate counts for numbers of H. maccallumi/100 erythrocytes for a series of 2,000 versus 4,000 erythrocytes counted; and (2) did not significantly increase the accuracy for determining parasite intensities. Thus, the number of erythrocytes that must be counted to determine parasite intensities could be considerably reduced from the 10,000 or 20,000 estimated for most studies, and still provide an accurate determination of the number of parasites/n erythrocytes in datasets collected from hosts with moderate to high levels of parasitemia. This resulted in a decreased amount of time expended by the observer on each blood smear examined. With two equivalently trained individuals, differences between observers examining the same blood smears were minimal. This study suggests an approach by which a more standardized methodology for quantifying blood parasite intensities could be developed. PMID:3119870

Godfrey, R D; Fedynich, A M; Pence, D B

1987-10-01

250

Blood Transfusions  

MedlinePLUS

... might be the red blood cells, platelets or plasma . Rarely is whole blood (red cells, plasma, platelets, and white cells) used for a transfusion. ... important for other components such as platelets and plasma, where most of the red blood cells have ...

251

BLOOD FLOW  

NSDL National Science Digital Library

The lesson is design to describe the factors affecting blood flow through the cardiovascular system. The lesson uses the 5E model as an approach for students to become engaged, analytical and inquisitive in learning about the mechanism of blood flow and the importance of this in our body. In addition, the lesson engages the student to test variables that may affect blood flow.

Cruz, Arnel D.

2012-06-28

252

Young Blood  

NSDL National Science Digital Library

A basketball team might look for "young blood" to pep up its starting lineup. Now, scientists are using young blood--literally--to revive aging muscles. This Science Update focuses on a study revealing that blood from younger mice stimulated stem cells and faster healing in the muscles and livers of older mice.

Science Update (;)

2005-04-04

253

The New York Times > Opinion > Making Votes Count: Count Every Vote December 20, 2004  

E-print Network

COUNT Count Every Vote very vote is supposed to count in America, but candidates too often maneuver to vote for her, but were tripped up by poor ballot design. The voters' intent should be recognizedThe New York Times > Opinion > Making Votes Count: Count Every Vote December 20, 2004 MAKING VOTES

Rivest, Ronald L.

254

Statistical Modeling of Storm Counts.  

NASA Astrophysics Data System (ADS)

A statistical model is presented of a recently compiled record of monthly extratropical storm counts for the mid-Atlantic coast of the United States for the period 1942-83. The counts are modeled as a Poisson process with nonstationary mean function. The mean function is decomposed into a secular component and a seasonal cycle. Because the form of the secular component is unknown, a nonparametric regression approach suitable for Poisson data is used to estimate it. The estimated secular component is generally constant through the 1950s, then declines through the 1970s. The estimate is found to be statistically significant. A Fourier series involving two harmonics is fit to the seasonal cycle. A preliminary check indicates that the seasonal cycle remains stable through time. Some diagnostics based on suitably defined residuals are presented that generally confirm the goodness-of-fit and distributional assumptions underlying the model.

Solow, Andrew R.

1989-02-01

255

Gap-Definable Counting Classes  

Microsoft Academic Search

The function class #P lacks an important closure property: it is not closed under subtraction.To remedy this problem, we introduce the function class GapP as a natural alternative to #P.GapP is the closure of #P under subtraction, and has all the other useful closure propertiesof #P as well. We show that most previously studied counting classes, including PP, C=P,and Mod

Stephen A. Fenner; Lance J. Fortnowt; Stuart A. Kurtz

1991-01-01

256

Evidence for counting in insects  

Microsoft Academic Search

Here we investigate the counting ability in honeybees by training them to receive a food reward after they have passed a specific\\u000a number of landmarks. The distance to the food reward is varied frequently and randomly, whilst keeping the number of intervening\\u000a landmarks constant. Thus, the bees cannot identify the food reward in terms of its distance from the hive.

Marie Dacke; Mandyam V. Srinivasan

2008-01-01

257

The Making Cases Count intiative.  

PubMed

Given the challenges faced, how can homeopaths communicate the power and scope of the therapeutic system of homeopathy? Homeopaths need to communicate to patients, the public and media, other healthcare professionals, healthcare researchers, and funders of healthcare (healthcare insurers, those who commission healthcare services either in publicly funded healthcare systems such as the NHS or charities). Effective communication with these stakeholders requires information that is: (a) easily understood, (b) credible, and (c) relevant. The patient's voice is the trusted, indisputable and easily understood common ground in homeopathy. Yet, the experiences of patients are rarely heard outside the profession of homeopathy. Homeopaths are in a unique position to make these voices heard by disseminating the results of their routine practice cases incorporating their patients' voices. The 'Making Cases Count' initiative has been created in order to bring about a culture where easily understood, trusted and salient information is regularly made available to all stakeholders in homeopathy. The Making Cases Count initiative supports, guides and incentives homeopaths to collect routine data with the aim of bringing about a culture where a significant proportion of homeopaths collect routine data from their patients in a format which will then be able to be transformed (i.e. anonymised, summarised and counted). This routine data requires numbers and categories to report the behavior and the perspective of patients receiving homeopathic treatment. This can be strengthened through the use of validated outcome measures in hearing patients' voices. When transformed, this routine data will then be able to inform homeopaths and more importantly other key stakeholders. It is now time to make patient cases count. PMID:25146064

Relton, C; Viksveen, P; Kessler, U

2014-08-01

258

Counting Squares in a Square  

NSDL National Science Digital Library

This Java applet displays one way of counting the smaller grid squares nested inside a larger grid square, such as a checkerboard or chessboard. The applet allows the user to select the size of the smaller grid square and drag it to other positions, tracking the upper left corner of each new square. The explanation reveals the formula for total number of grid squares within a N x N grid square: the sum of the first N squares.

Interactive Math Miscellany And Puzzles, Alexander B.

2011-01-01

259

1999 KIDS COUNT Data Book  

NSDL National Science Digital Library

The Annie E. Casey Foundation, a private charitable organization, aims to initiate and develop "public policies, human-service reforms, and community supports" to assist disadvantaged children in the US. One of the principal activities of the organization is the publication of the KIDS COUNT Data Book, "which uses the best available data to measure the educational, social, economic, and physical well-being of children" all over the US. This site offers public access to the online database for the 1999 KIDS COUNT Data Book. Included are tables of state and national data profiles based on statistical indicators, lists of states ranked by indicator, interactive line graphs allowing users to compare indicators from up to eight areas, and color-coded US maps representing KIDS COUNT data. Users can download all of the raw data files for 1999 in a compressed .zip file or they may download raw data files individually as either a MS Excel spreadsheet file (.xls) or a comma-delimited text file (.csv).

260

Number Systems: Finger Counting (Session 1)  

NSDL National Science Digital Library

In this project you will examine number systems from various cultures around the world. Session 1: First let's begin by examining how other cultures finger count. First examine Image of Ancient Chinese finger counting system. 1.What do you notice about this counting system? 2.How are the fingers used in this system? Now watch the Youtube video finger counting to 10 in Chinese. Now Learn how to finger count to 10 in Chinese. What numbers are similar to our own finger counting system? At what point ...

Nunes-Bufford, Mrs.

2008-12-01

261

Leukocyte nucleus segmentation and nucleus lobe counting  

PubMed Central

Background Leukocytes play an important role in the human immune system. The family of leukocytes is comprised of lymphocytes, monocytes, eosinophils, basophils, and neutrophils. Any infection or acute stress may increase or decrease the number of leukocytes. An increased percentage of neutrophils may be caused by an acute infection, while an increased percentage of lymphocytes can be caused by a chronic bacterial infection. It is important to realize an abnormal variation in the leukocytes. The five types of leukocytes can be distinguished by their cytoplasmic granules, staining properties of the granules, size of cell, the proportion of the nuclear to the cytoplasmic material, and the type of nucleolar lobes. The number of lobes increased when leukemia, chronic nephritis, liver disease, cancer, sepsis, and vitamin B12 or folate deficiency occurred. Clinical neutrophil hypersegmentation has been widely used as an indicator of B12 or folate deficiency.Biomedical technologists can currently recognize abnormal leukocytes using human eyes. However, the quality and efficiency of diagnosis may be compromised due to the limitations of the biomedical technologists' eyesight, strength, and medical knowledge. Therefore, the development of an automatic leukocyte recognition system is feasible and necessary. It is essential to extract the leukocyte region from a blood smear image in order to develop an automatic leukocyte recognition system. The number of lobes increased when leukemia, chronic nephritis, liver disease, cancer, sepsis, and vitamin B12 or folate deficiency occurred. Clinical neutrophil hypersegmentation has been widely used as an indicator of B12 or folate deficiency. Results The purpose of this paper is to contribute an automatic leukocyte nuclei image segmentation method for such recognition technology. The other goal of this paper is to develop the method of counting the number of lobes in a cell nucleus. The experimental results demonstrated impressive segmentation accuracy. Conclusions Insensitive to the variance of images, the LNS (Leukocyte Nuclei Segmentation) method functioned well to isolate the leukocyte nuclei from a blood smear image with much better UR (Under Segmentation Rate), ER (Overall Error Rate), and RDE (Relative Distance Error). The presented LC (Lobe Counting) method is capable of splitting leukocyte nuclei into lobes. The experimental results illuminated that both methods can give expressive performances. In addition, three advanced image processing techniques were proposed as weighted Sobel operator, GDW (Gradient Direction Weight), and GBPD (Genetic-based Parameter Detector). PMID:21073711

2010-01-01

262

The relationship between red blood cell distribution width and blood pressure in patients with type 2 diabetes mellitus in Lagos, Nigeria  

PubMed Central

Background High red blood cell distribution width (RDW) is related to impairment of erythropoiesis, reflecting chronic inflammation and increased levels of oxidative stress, both of which are telltale signs of type 2 diabetics. The aim of this study was to evaluate the relationship between the RDW and fasting blood sugar/blood pressure, and compare the results from diabetics with nondiabetic controls. Methods This was an unmatched case-control study involving 200 participants consisting of 100 diabetics and 100 nondiabetic controls. Blood (4.5 mL) was collected from all of the diabetics and nondiabetic controls, and placed into EDTA anticoagulant tubes. A full blood count was performed using the Sysmex KX-21N, a three-part auto analyzer able to run 19 parameters per sample, including RDW. Blood pressure was measured during sample collection and in a sitting position. Results The mean fasting blood sugar level was 95.20±30.10 mg/dL in the controls, and 147.85±72.54 mg/dL in the diabetics. The mean blood pressures for diabetics was 138/90 mmHg and for non-diabetics 120/80 mmHg. The mean RDW-SD (RDW standard deviation) was 46.44±4.64 fl in the controls, and 46.84±3.18 in the diabetics. The mean RDW-CV (RDW coefficient of variation) was 14.74%±1.94% in controls, and 14.80±0.71 for diabetics. No statistically significant correlation was found between the RDW-SD and fasting blood sugar/blood pressure in the diabetics. A statistically significant positive correlation was found between the RDW-CV and blood pressure in the diabetics. Conclusion A positive correlation between the RDW-CV and blood pressure was established in the diabetics in this study. PMID:25278786

Dada, Olusola Akinola; Uche, Ebele; Akinbami, Akinsegun; Odesanya, Majeed; John-Olabode, Sarah; Adediran, Adewumi; Oshinaike, Olajumoke; Ogbera, Anthonia Okeoghene; Okunoye, Olaitan; Arogundade, Olanrewaju; Aile, Kingsley; Ekwere, Timothy

2014-01-01

263

Platelet counting-development of a reference method and a reference preparation.  

PubMed

A reference method has been defined for platelet counting by counting chamber haemocytometry, and a procedure has been developed, using platelet rich plasma (PRP) and a Coulter ZBI counter which provides a reliable, rapid and relatively simple method for platelet counting which is closely comparable to the reference method and can thus be used both as a secondary reference method and a routine method. The optimal method for obtaining PRP from EDTA blood was by augmented sedimentation with Boyum's methyl cellulose-metrizoate mixture at sp. gr. 1.08. This was shown to yield a platelet suspension which reflects closely the platelet content of the original blood. Calibration of electronic counters for platelet counting requires material which is stable and which parallels natural human platelets in size, distribution and other physical characteristics. A suspension of glutaraldehyde-fixed human platelets in glycerol appears to be suitable as a reference preparation. Its method of production is described. PMID:535315

Lewis, S M; Wardle, J; Cousins, S; Skelly, J V

1979-01-01

264

Drying drops of blood  

NASA Astrophysics Data System (ADS)

The drying of a drop of human blood is fascinating by the complexity of the physical mechanisms that occur as well as the beauty of the phenomenon which has never been previously evidenced in the literature. The final stage of full blood evaporation reveals for a healthy person the same regular pattern with a good reproducibility. Other tests on anemia and hyperlipidemic persons were performed and presented different patterns. By means of digital camera, the influence of the motion of red blood cells (RBCs) which represent about 50% of the blood volume, is revealed as well as its consequences on the final stages of drying. The mechanisms which lead to the final pattern of dried blood drops are presented and explained on the basis of fluid and solid mechanics in conjunction with the principles of hematology. Our group is the first to evidence that the specific regular patterns characteristic of a healthy individual do not appear in a dried drop of blood from a person with blood disease. Blood is a complex colloidal suspension for which the flow motion is clearly non-Newtonian. When drops of blood evaporate, all the colloids are carried by the flow motion inside the drop and interact.

Brutin, David; Sobac, Benjamin; Loquet, Boris; Sampol, José.

2010-11-01

265

Photon counting with passively quenched germanium avalanche.  

PubMed

We demonstrate photon counting in germanium avalanche photodiodes biased beyond breakdown and quenched with a simple series resistance circuit. The devices show moderate (> 7%) quantum efficiency with limited afterpulsing and dark counts and subnanosecond jitter. PMID:20941236

Owens, P C; Rarity, J G; Tapster, P R; Knight, D; Townsend, P D

1994-10-20

266

Modeling and simulation of count data.  

PubMed

Count data, or number of events per time interval, are discrete data arising from repeated time to event observations. Their mean count, or piecewise constant event rate, can be evaluated by discrete probability distributions from the Poisson model family. Clinical trial data characterization often involves population count analysis. This tutorial presents the basics and diagnostics of count modeling and simulation in the context of pharmacometrics. Consideration is given to overdispersion, underdispersion, autocorrelation, and inhomogeneity. PMID:25116273

Plan, E L

2014-01-01

267

Count rate limitations in pulsed accelerator fields  

SciTech Connect

This paper discusses various concepts involved in the counting losses of pulse-counting health physics instrumentation when used within the pulsed radiation environments of typical accelerator fields, in order to pre-establish appropriate limitations in use. Discussed are the 'narrow' pulse and the 'wide' pulse cases, the special effect of neutron moderating assemblies, and the effect of pulse microstructure on the counting losses of the pulse-counting instrumentation. Examples are provided which highlight the various concepts and limitations.

Justus, Alan L [Los Alamos National Laboratory

2010-12-15

268

A side-by-side evaluation of four platelet-counting instruments.  

PubMed

The performances of four instruments for counting platelets were evaluated in a side-by-side study: the Haema-Count MK-4/HC, an electronic impedance instrument that counts platelets in platelet-rich plasma; the Ultra-Flo 100, and the Coulter Counter Model S-Plus, electronic impedance instruments that count platelets in the presence of intact erythrocytes; and the AutoCounter, an optical instrument that counts platelets in the presence of lysed erythrocytes. The Ultra-Flo 100 and the S-Plus showed the best within-run precision, and all four instruments were considerably more precise than manual platelet counting, especially at low levels of platelet count. The four instruments were all linear in the ranges tested (5 to 650 x 10(9)/or greater), and sample carry-over was less than 0.7% for each. A noteworthy finding was that the erythrocyte concentration of the blood samples affected the displayed platelet count of the S-Plus and, to a lesser extent, that of the AutoCounter, in a predictable way, whereas it did not greatly affect the displayed count of the Ultra-Flo 100. In addition to differences in quality of performances, the four instruments differed considerably in speed and ease of operation and in cost. PMID:7405890

Dalton, W T; Bollinger, P; Drewinko, B

1980-08-01

269

Importance of counting in biology.  

PubMed

In this study, analysis of biological problems through structural and quantitative approaches is described. Classical genetics on major histocompatibility complex in avian species has been evaluated. Experiments showing that antibodies from various individuals were generally distinct have led to further analysis of immunoglobulin light chain diversity by means of O'Farrell's 2D gel technique. The transition of the research towards vaccine development has been described. 'It's not the voting that's democracy, it's the counting.' - Tom Stoppard (Czech-born dramatist), Jumpers (1972) act 1. PMID:15953182

Pink, J R L

2005-07-01

270

1.NBT Counting Circles II  

NSDL National Science Digital Library

This is a task from the Illustrative Mathematics website that is one part of a complete illustration of the standard to which it is aligned. Each task has at least one solution and some commentary that addresses important asects of the task and its potential use. Here are the first few lines of the commentary for this task: Setup Have students stand and form a circle facing in toward each other. Select a counting sequence to be practiced with no more than 6-10 numbers in t...

271

Blood Analyzer  

NASA Technical Reports Server (NTRS)

In the 1970's, NASA provided funding for development of an automatic blood analyzer for Skylab at the Oak Ridge National Laboratory (ORNL). ORNL devised "dynamic loading," which employed a spinning rotor to load, transfer, and analyze blood samples by centrifugal processing. A refined, commercial version of the system was produced by ABAXIS and is marketed as portable ABAXIS MiniLab MCA. Used in a doctor's office, the equipment can perform 80 to 100 chemical blood tests on a single drop of blood and report results in five minutes. Further development is anticipated.

1992-01-01

272

NATURAL VARIATION IN SPOTTING, HYOID TEETH COUNTS,  

E-print Network

^i^^- fV/ NATURAL VARIATION IN SPOTTING, HYOID TEETH COUNTS, AND COLORATION OF YELLOWSTONE and Wildlife, Daniel H. Janzen, Director NATURAL VARIATION IN SPOTTING, HYOID TEETH COUNTS, AND COLORATION cited 10 Appendix ,, 11 #12;#12;NATURAL VARIATION IN SPOTTING, HYOID TEETH COUNTS, AND COLORATION

273

DC KIDS COUNT e-Databook Indicators  

ERIC Educational Resources Information Center

This report presents indicators that are included in DC Action for Children's 2012 KIDS COUNT e-databook, their definitions and sources and the rationale for their selection. The indicators for DC KIDS COUNT represent a mix of traditional KIDS COUNT indicators of child well-being, such as the number of children living in poverty, and indicators of…

DC Action for Children, 2012

2012-01-01

274

Monte Carlo Simulation of Counting Experiments.  

ERIC Educational Resources Information Center

A computer program to perform a Monte Carlo simulation of counting experiments was written. The program was based on a mathematical derivation which started with counts in a time interval. The time interval was subdivided to form a binomial distribution with no two counts in the same subinterval. Then the number of subintervals was extended to…

Ogden, Philip M.

275

Blood (For Parents)  

MedlinePLUS

... about the mysterious, life-sustaining fluid called blood. Blood Basics Two types of blood vessels carry blood ... mixture of blood cells and plasma. Continue Red Blood Cells Red blood cells (also called erythrocytes) are ...

276

Effective estimation of correct platelet counts in pseudothrombocytopenia using an alternative anticoagulant based on magnesium salt.  

PubMed

Pseudothrombocytopenia remains a challenge in the haematological laboratory. The pre-analytical problem that platelets tend to easily aggregate in vitro, giving rise to lower platelet counts, has been known since ethylenediamine-tetra acetic acid EDTA and automated platelet counting procedures were introduced in the haematological laboratory. Different approaches to avoid the time and temperature dependent in vitro aggregation of platelets in the presence of EDTA were tested, but none of them proved optimal for routine purposes. Patients with unexpectedly low platelet counts or flagged for suspected aggregates, were selected and smears were examined for platelet aggregates. In these cases patients were asked to consent to the drawing of an additional sample of blood anti-coagulated with a magnesium additive. Magnesium was used in the beginning of the last century as anticoagulant for microscopic platelet counts. Using this approach, we documented 44 patients with pseudothrombocytopenia. In all cases, platelet counts were markedly higher in samples anti-coagulated with the magnesium containing anticoagulant when compared to EDTA-anticoagulated blood samples. We conclude that in patients with known or suspected pseudothrombocytopenia the magnesium-anticoagulant blood samples may be recommended for platelet counting. PMID:23808903

Schuff-Werner, Peter; Steiner, Michael; Fenger, Sebastian; Gross, Hans-Jürgen; Bierlich, Alexa; Dreissiger, Katrin; Mannuß, Steffen; Siegert, Gabriele; Bachem, Maximilian; Kohlschein, Peter

2013-09-01

277

Modified single photon counting modules for optimal timing performance  

NASA Astrophysics Data System (ADS)

A modification of a standard Perkin Elmer SPCM-AQR photon detector module that remarkably improves the photon timing performance is presented here. The modification consists of an additional timing circuit board, which is inserted in the module without modifying the original circuit board. The essential feature is a pulse pickup linear network, connected to the high-voltage terminal of the photodetector, which extracts a short pulse signal with fast rise, coincident with the rise of the avalanche current. The information about the photon arrival time is obtained by sensing the onset of the rise. At low counting rates (<105counts/s) time-correlated photon counting tests show that the instrumental resolution function (IRF) thus obtained has full width at half maximum (FWHM) narrower by about 40% with respect to the original module. At higher counting rate, up to few Mcounts/s, the advantage is even more remarkable: The timing circuit practically eliminates the drawbacks that plague the original module, namely, a progressive increase of the FWHM and a progressive shift of the peak position of the IRF with increasing counting rate. The modified SPCM-AQR module is therefore suitable also for applications requiring subnanosecond time resolution at high and/or variable counting rate, such as fluorescent decay measurements, fluorescent lifetime imaging, single molecule detection and spectroscopy, and optical radar techniques.

Rech, I.; Labanca, I.; Ghioni, M.; Cova, S.

2006-03-01

278

Optimization of a cell counting algorithm for mobile point-of-care testing platforms.  

PubMed

In a point-of-care (POC) setting, it is critically important to reliably count the number of specific cells in a blood sample. Software-based cell counting, which is far faster than manual counting, while much cheaper than hardware-based counting, has emerged as an attractive solution potentially applicable to mobile POC testing. However, the existing software-based algorithm based on the normalized cross-correlation (NCC) method is too time- and, thus, energy-consuming to be deployed for battery-powered mobile POC testing platforms. In this paper, we identify inefficiencies in the NCC-based algorithm and propose two synergistic optimization techniques that can considerably reduce the runtime and, thus, energy consumption of the original algorithm with negligible impact on counting accuracy. We demonstrate that an AndroidTM smart phone running the optimized algorithm consumes 11.5× less runtime than the original algorithm. PMID:25195851

Ahn, DaeHan; Kim, Nam Sung; Moon, SangJun; Park, Taejoon; Son, Sang Hyuk

2014-01-01

279

Optimization of a Cell Counting Algorithm for Mobile Point-of-Care Testing Platforms  

PubMed Central

In a point-of-care (POC) setting, it is critically important to reliably count the number of specific cells in a blood sample. Software-based cell counting, which is far faster than manual counting, while much cheaper than hardware-based counting, has emerged as an attractive solution potentially applicable to mobile POC testing. However, the existing software-based algorithm based on the normalized cross-correlation (NCC) method is too time- and, thus, energy-consuming to be deployed for battery-powered mobile POC testing platforms. In this paper, we identify inefficiencies in the NCC-based algorithm and propose two synergistic optimization techniques that can considerably reduce the runtime and, thus, energy consumption of the original algorithm with negligible impact on counting accuracy. We demonstrate that an Android™ smart phone running the optimized algorithm consumes 11.5× less runtime than the original algorithm. PMID:25195851

Ahn, DaeHan; Kim, Nam Sung; Moon, SangJun; Park, Taejoon; Son, Sang Hyuk

2014-01-01

280

Blood Sugar  

MedlinePLUS

... an A1C. It checks your average blood sugar level over the past three months. If your blood sugar is too high, you may need to take medicines and/or follow a special diet. Centers for Disease Control and Prevention

281

Kids Count in Delaware, Families Count in Delaware: Fact Book, 2003.  

ERIC Educational Resources Information Center

This Kids Count Fact Book is combined with the Families Count Fact Book to provide information on statewide trends affecting children and families in Delaware. The Kids Count and Families Count indicators have been combined into four new categories: health and health behaviors, educational involvement and achievement, family environment and…

Delaware Univ., Newark. Kids Count in Delaware.

282

"Every Vote Counts. Electronic Voting and Counting" Electronic Voting at Polling Stations Study Commission in the  

E-print Network

"Every Vote Counts. Electronic Voting and Counting" Electronic Voting at Polling Stations Study is permitted to cast one vote per election, which is counted once only in the counting of votes; Accessibility. The control tools may differ, depending on the method of voting decided on; Free suffrage: In casting his

Hoepman, Jaap-Henk

283

Photon counting compressive depth mapping.  

PubMed

We demonstrate a compressed sensing, photon counting lidar system based on the single-pixel camera. Our technique recovers both depth and intensity maps from a single under-sampled set of incoherent, linear projections of a scene of interest at ultra-low light levels around 0.5 picowatts. Only two-dimensional reconstructions are required to image a three-dimensional scene. We demonstrate intensity imaging and depth mapping at 256 × 256 pixel transverse resolution with acquisition times as short as 3 seconds. We also show novelty filtering, reconstructing only the difference between two instances of a scene. Finally, we acquire 32 × 32 pixel real-time video for three-dimensional object tracking at 14 frames-per-second. PMID:24104293

Howland, Gregory A; Lum, Daniel J; Ware, Matthew R; Howell, John C

2013-10-01

284

Enumeration of CD4+ T-Cells Using a Portable Microchip Count Platform in Tanzanian HIV-Infected Patients  

Microsoft Academic Search

BackgroundCD4+ T-lymphocyte count (CD4 count) is a standard method used to monitor HIV-infected patients during anti-retroviral therapy (ART). The World Health Organization (WHO) has pointed out or recommended that a handheld, point-of-care, reliable, and affordable CD4 count platform is urgently needed in resource-scarce settings.MethodsHIV-infected patient blood samples were tested at the point-of-care using a portable and label-free microchip CD4 count

SangJun Moon; Umut Atakan Gurkan; Jeffrey Blander; Wafaie W. Fawzi; Said Aboud; Ferdinand Mugusi; Daniel R. Kuritzkes; Utkan Demirci

2011-01-01

285

Cuprophan reuse and intradialytic changes of lung diffusion capacity and blood gasses  

Microsoft Academic Search

Cuprophan reuse and intradialytic changes of lung diffusion capacity and arterial blood gasses. The changes in arterial blood gas, pulmonary function tests, leukocyte counts and complement activition were evaluated during first use and subsequent reuse of cuprophan dialyzers. The dialysate buffer was bicarbonate. Reuse of cuprophan dialyzers significantly attenuated the fall in leukocyte counts and the rise in C3a des

Raymond C Vanholder; Romain A Pauwels; Johan F Vandenbogaerde; Herman H Lamont; Marcel E Van Der Straeten; Severin M Ringoir

1987-01-01

286

Blood Facts and Statistics  

MedlinePLUS

... About Blood > Blood Facts and Statistics Printable Version Blood Facts and Statistics Facts about blood needs Facts ... about American Red Cross Blood Services Facts about blood needs Every two seconds someone in the U.S. ...

287

Biology of Blood  

MedlinePLUS

... Multimedia Table Index In This Topic Blood Disorders Biology of Blood Overview of Blood Back to Top ... Subjects Women's Health Issues Chapters in Blood Disorders Biology of Blood Symptoms and Diagnosis of Blood Disorders ...

288

Blood Transfusion  

MedlinePLUS

... practice to prevent complications of anemia, such as fatigue, weakness, shortness of breath or in extreme cases, ... your blood { { Whether you have symptoms such as fatigue or shortness of breath { { Any other health complications ...

289

Blood typing  

MedlinePLUS

... are slight but may include: Fainting or feeling light-headed Multiple punctures to locate veins Excessive bleeding Hematoma (blood accumulating under the skin) Infection (a slight risk any time the skin is broken)

290

Amylase - blood  

MedlinePLUS

Amylase is an enzyme that helps digest carbohydrates. It is produced in the pancreas and the glands ... saliva. When the pancreas is diseased or inflamed, amylase releases into the blood. A test can be ...

291

Estimating relative abundance from count data  

USGS Publications Warehouse

Much of the available information on large-scale patterns of animal abundance is based on count surveys. The data provided by such surveys are often influenced by nuisance factors affecting the numbers of animals counted, but unrelated to population size. Temporal and spatial patterns in nuisance factors may exist, causing simple summaries of counts to give a misleading view of patterns in population size. We develop models for count data that allows the incorporation of such factors, and describe methods for estimating spatial patterns of relative abundance from counts. We carry out spatial analyses of North American Breeding Bird Survey data, in which observer ability is a nuisance parameter nested within sites. In light of evidence that new observers tend to count more birds than the observers they replace, we model observer ability as a random effect with mean depending on observer initiation year.

Link, W.A.; Sauer, J.R.

1998-01-01

292

Estimation of atomic interaction parameters by photon counting  

NASA Astrophysics Data System (ADS)

Detection of radiation signals is at the heart of precision metrology and sensing. In this article we show how the fluctuations in photon-counting signals can be exploited to optimally extract information about the physical parameters that govern the dynamics of the emitter. For a simple two-level emitter subject to photon counting, we show that the Fisher information and the Cramér-Rao sensitivity bound based on the full detection record can be evaluated from the waiting-time distribution in the fluorescence signal which can, in turn, be calculated for both perfect and imperfect detectors by a quantum trajectory analysis. We provide an optimal estimator achieving that bound.

Kiilerich, Alexander Holm; Mølmer, Klaus

2014-05-01

293

What I Need to Know about Carbohydrate Counting and Diabetes  

MedlinePLUS

... and Diabetes What I need to know about Carbohydrate Counting and Diabetes On this page: What is ... Pronunciation Guide For More Information Acknowledgments What is carbohydrate counting? Carbohydrate * counting, also called carb counting, is ...

294

Full Counting Statistics for a Single-Electron Transistor: Nonequilibrium Effects at Intermediate Conductance  

NASA Astrophysics Data System (ADS)

We evaluate the current distribution for a single-electron transistor with intermediate strength tunnel conductance. Using the Schwinger-Keldysh approach and the drone (Majorana) fermion representation, we account for the renormalization of system parameters. Nonequilibrium effects induce a lifetime broadening of the charge-state levels, which suppress large current fluctuations.

Utsumi, Yasuhiro; Golubev, Dmitri S.; Schön, Gerd

2006-03-01

295

Counting dark matter particles in LHC events  

NASA Astrophysics Data System (ADS)

We suggest trying to count the number of invisible particles produced in missing energy events at the LHC, arguing that multiple production of such particles provides evidence that they constitute stable dark matter and that counting them could yield further insights into the nature of dark matter. We propose a method to count invisible particles, based on fitting the shapes of certain transverse- or invariant-mass distributions, discuss various effects that may affect the measurement, and simulate the use of the method to count neutrinos in standard model processes and dark matter candidates in new physics processes.

Giudice, Gian Francesco; Gripaios, Ben; Mahbubani, Rakhi

2012-04-01

296

Effect of counting errors on immunoassay precision  

SciTech Connect

Using mathematical analysis and computer simulation, we studied the effect of gamma scintillation counting error on two radioimmunoassays (RIAs) and an immunoradiometric assay (IRMA). To analyze the propagation of the counting errors into the estimation of analyte concentration, we empirically derived parameters for logit-log data-reduction models for assays of digoxin and triiodothyronine (RIAs) and ferritin (IRMA). The component of the analytical error attributable to counting variability, when expressed as a CV of the analyte concentration, decreased approximately linearly with the inverse of the square root of the maximum counts bound. Larger counting-error CVs were found at lower concentrations for both RIAs and the IRMA. Substantially smaller CVs for overall assay were found when the maximum counts bound progressively increased from 500 to 10,000 counts, but further increases in maximum bound counts resulted in little decrease in overall assay CV except when very low concentrations of analyte were being measured. Therefore, RIA and IRMA systems based in duplicate determinations having at least 10,000 maximum counts bound should have adequate precision, except possibly at very low concentrations.

Klee, G.G.; Post, G. (Mayo Foundation, Rochester, MD (USA))

1989-07-01

297

Portable microfluidic cytometer for whole blood cell analysis  

NASA Astrophysics Data System (ADS)

Lab-on-a-chip (LOC) systems allow complex laboratory assays to be carried out on a single chip using less time, reagents, and manpower than traditional methods. There are many chips addressing PCR and other DNA assays, but few that address blood cell analysis. Blood analysis, particularly of the cellular component, is highly important in both medical and scientific fields. Traditionally blood samples require a vial of blood, then several processing steps to separate and stain the various components, followed by the preparations for each specific assay to be performed. A LOC system for blood cell analysis and sorting would be ideal. The microfluidic-based system we have developed requires a mere drop of blood to be introduced onto the chip. Once on chip, the blood is mixed with both fluorescent and magnetic labels. The lab-on-a-chip device then uses a syringe drive to push the cells through the chip, while a permanent magnet is positioned to pull the magnetically labeled white blood cells to a separate channel. The white blood cells, labeled with different color fluorescent quantum dots (Qdots) conjugated to antibodies against WBC subpopulations, are analyzed and counted, while a sampling of red blood cells is also counted in a separate channel. This device will be capable of processing whole blood samples on location in a matter of minutes and displaying the cell count and should eventually find use in neonatology, AIDS and remote site applications.

Grafton, Meggie M.; Zordan, Michael D.; Chuang, Han-Sheng; Rajdev, Pooja; Reece, Lisa M.; Irazoqui, Pedro P.; Wereley, Steven T.; Byrnes, Ron; Todd, Paul; Leary, James F.

2010-02-01

298

Young Blood  

NSDL National Science Digital Library

Old muscles heal faster when they're exposed to young blood. That's the conclusion of a recent experiment in mice, led by Stanford University neurologist Thomas Rando. His team found that blood from younger mice stimulated stem cells in the muscles and livers of older mice. Those are the cells that generate new tissue. It's not clear what part of the young blood makes the difference, but Dr. Rando suspects it's a combination of factors. If scientists can solve the mystery, they may be able to develop new ways to help injuries and broken bones heal more quickly. This Science Update looks at the research, which leads to these findings and offers links to other resources for further inquiry. There are also links to Science Netlinks Lesson plans for use at the 6-8 grade level.

American Association for the Advancement of Science (;)

2005-04-04

299

Negative Binomial Process Count and Mixture Modeling  

E-print Network

1 Negative Binomial Process Count and Mixture Modeling Mingyuan Zhou and Lawrence Carin Abstract The seemingly disjoint problems of count and mixture modeling are united under the negative binomial (NB process, gamma process, hierarchical Dirichlet process, mixed membership modeling, mixture modeling

Carin, Lawrence

300

"Knots on a Counting Rope": Teaching Stories.  

ERIC Educational Resources Information Center

Argues that reflecting on important "marker" stories in people's lives by using counting ropes (based on the children's book "Knots on a Counting Rope" by Bill Martin Jr. and John Archambault) helps students and teachers make sense of their complex worlds. Describes how they are used in the author's language arts methods course. Describes a…

Key, Daphne

2001-01-01

301

Kids Count in Indiana: 1996 Data Book.  

ERIC Educational Resources Information Center

This Kids Count report is the third in a series examining statewide trends in the well-being of Indiana's children. The report combines statistics of special concern in Indiana with 10 national Kids Count well-being indicators: (1) percent low birthweight; (2) infant mortality rate; (3) child death rate; (4) birth rate to unmarried teens ages 15…

Erickson, Judith B.

302

Discover Number Patterns With Skip Counting  

NSDL National Science Digital Library

In this 7-minute video third grade teacher Laretha Todd explains and models the strategy of choral counting with her students. As she records their counting, students are able to see patterns emerge and share and explain their findings. Questions for teacher reflection are included as well as a transcript.

2012-01-01

303

2008 KidsCount in Colorado!  

ERIC Educational Resources Information Center

"KidsCount in Colorado!" is an annual publication of the Colorado Children's Campaign, which provides the best available state- and county-level data to measure and track the education, health and general well-being of the state's children. KidsCount in Colorado! informs policy debates and community discussions, serving as a valuable resource for…

Colorado Children's Campaign, 2008

2008-01-01

304

2009 KidsCount in Colorado!  

ERIC Educational Resources Information Center

"KidsCount in Colorado!" is an annual publication of the Colorado Children's Campaign, which provides the best available state- and county-level data to measure and track the education, health and general well-being of the state's children. KidsCount in Colorado! informs policy debates and community discussions, serving as a valuable resource for…

Colorado Children's Campaign, 2009

2009-01-01

305

BIJECTIVE COUNTING OF INVOLUTIVE BAXTER PERMUTATIONS  

E-print Network

in each row and in each column. With this representation in mind, it is known (see e.g. [4]) that the set group acting on the grid G. So it is a natural problem to try to count how many Baxter permutationsBIJECTIVE COUNTING OF INVOLUTIVE BAXTER PERMUTATIONS ´ERIC FUSY Abstract. We enumerate bijectively

Fusy, Ã?ric

306

Early Concepts of Number and Counting  

ERIC Educational Resources Information Center

Before primitive man had grasped the concept of number, the written word or even speech, he was able to count. This was important for keeping track of food supplies, sending messages, trading between villages and even keeping track of how many animals were in their herd. Counting was done in various ways, but in all cases, the underlying principle…

Box, Katherine; Scott, Paul

2004-01-01

307

Using Carbohydrate Counting in Diabetes Clinical Practice  

Microsoft Academic Search

Carbohydrate counting is a meal planning approach used with clients who have diabetes that focuses on carbohydrate as the primary nutrient affecting postprandial glycemic response. The concept of carbohydrate counting has been around since the 1920s, but it received renewed interest after being used as 1 of 4 meal planning approaches in the Diabetes Control and Complications Trial. In the

SANDRA J GILLESPIE; KARMEEN D KULKARNI; ANNE E DALY

1998-01-01

308

Blood Vessels  

NSDL National Science Digital Library

Part of the circulatory system is composed of a series of tubes carries the vital elements and the wastes that keep us strong and healthy. Take a look at these amazing vessels and how they work together. Ever cut yourself on the toe? How about the finger? The ear? Ever get a bloody nose? How about a scrape on the knee? If these things have ever happened to you then you already know that blood vessels carry blood to EVERY part of the body. They start out ...

Hirschi, Mrs.

2007-11-20

309

Leucocyte Blood Picture in Ill Newborn Babies  

PubMed Central

Serial blood leucocyte counts were made on 35 ill preterm and term babies during the first 28 days of life. Ill babies with no clinical or bacteriological evidence of infection showed no changes in the blood leucocytes during the neonatal period when compared with normal babies. The changes in the blood leucocytes in babies with proven or suspected bacterial infection were an increase in the absolute values of polymorphonuclear neutrophils, an increase in the absolute values of immature neutrophils, a significant fall in polymorphonuclear neutrophils (below 1000/mm3) and in eosinophils (down to 0) in very ill babies, and toxic granulation of neutrophils. ImagesFIG. 3 PMID:4563923

Xanthou, Marietta

1972-01-01

310

Kids Count in Delaware: Fact Book 1999 [and] Families Count in Delaware: Fact Book, 1999.  

ERIC Educational Resources Information Center

This Kids Count Fact Book is combined with the Families Count Fact Book to provide information on statewide trends affecting children and families in Delaware. The Kids Count statistical profile is based on 10 main indicators of child well-being: (1) births to teens; (2) low birth weight babies; (3) infant mortality; (4) child deaths; (5) teen…

Delaware Univ., Newark. Kids Count in Delaware.

311

Kids Count in Delaware, Families Count in Delaware: Fact Book, 2002.  

ERIC Educational Resources Information Center

This Kids Count Fact Book is combined with the Families Count Fact Book to provide information on statewide trends affecting children and families in Delaware. The Kids Count statistical profile is based on 11 main indicators of child well-being: (1) births to teens 15-17 years; (2) births to teens 10 to 14 years; (3) low birth weight babies; (3)…

Delaware Univ., Newark. Kids Count in Delaware.

312

Effect of 6-day intense Kendo training on lymphocyte counts and its expression of CD95.  

PubMed

This study examines the effects of 6-day intensive training on lymphocyte counts and their expression of CD95. Eight healthy Kendo athletes underwent 6-day Kendo training of about 310 min each day. Blood samples were collected at 2 weeks before (PRE), the first day (Day 1), third day (Day 3), fifth day (Day 5), and 1 week after the training period (POST) to determine lymphocyte counts and CD95 expression on CD95 lymphocytes (CD4(+), CD8(+)) using flow cytometry. The total lymphocyte counts were significantly lower at Day 3 than at PRE. The CD8(+) cell counts were significantly lower at Day 3 than at PRE. The percentage of CD95(+) lymphocytes was significantly higher at Day 1 and Day 3 than at PRE. The percentage of CD8(+)CD95(+) cells did not change significantly. The total lymphocyte counts decreased and a concomitant increase of CD95(+) lymphocyte was observed, whereas the decrease in CD8(+) cell counts was not associated with the increase in CD8(+)CD95(+) cells. Therefore, short-term high-intensity exercise induced a decrease in the T lymphocyte counts without increasing in CD95(+) expression. PMID:19568765

Tanimura, Yuko; Kon, Michihiro; Shimizu, Kazuhiro; Kimura, Fuminori; Kono, Ichiro; Ajisaka, Ryuichi

2009-09-01

313

Blood gases  

MedlinePLUS

... the groin Brachial artery in the arm The health care provider may test circulation to the hand before taking a sample ... must remain constant for 20 minutes before the test. Tell your health care provider if you are taking any blood-thinning ...

314

Blood Types  

E-print Network

is the warrior, loyal and ambitious. This is known as blood-typology and it occupies a neat little segment of Japanese pop culture. It is used for dating, and in employment, and by marketers to sell products ranging from soft drinks to condoms. Recently, the Red...

Hacker, Randi; Tsutsui, William

2007-03-14

315

Blood pressure measurement  

MedlinePLUS

Diastolic blood pressure; Systolic blood pressure; Blood pressure reading; Measuring blood pressure ... bare. You or your doctor will wrap the blood pressure cuff snugly around your upper arm. The ...

316

Understanding Blood Pressure Readings  

MedlinePLUS

Understanding Blood Pressure Readings Updated:Sep 3,2014 Blood pressure is typically recorded as two numbers, written as a ... blood). What is the AHA recommendation for healthy blood pressure? This chart reflects blood pressure categories defined ...

317

What Is Blood?  

MedlinePLUS

... fight infection, carry oxygen and help control bleeding. Plasma carries blood cells. Plasma is the liquid portion of your blood that ... to view compatibility. RED BLOOD CELLS WHOLE BLOOD PLASMA Donor O Group O can donate red blood ...

318

Full moon and crime.  

PubMed Central

The incidence of crimes reported to three police stations in different towns (one rural, one urban, one industrial) was studied to see if it varied with the day of the lunar cycle. The period of the study covered 1978-82. The incidence of crimes committed on full moon days was much higher than on all other days, new moon days, and seventh days after the full moon and new moon. A small peak in the incidence of crimes was observed on new moon days, but this was not significant when compared with crimes committed on other days. The incidence of crimes on equinox and solstice days did not differ significantly from those on other days, suggesting that the sun probably does not influence the incidence of crime. The increased incidence of crimes on full moon days may be due to "human tidal waves" caused by the gravitational pull of the moon. PMID:6440656

Thakur, C P; Sharma, D

1984-01-01

319

Reduced Neutrophil Count in People of African Descent Is Due To a Regulatory Variant in the Duffy Antigen Receptor for Chemokines Gene  

Microsoft Academic Search

Persistently low white blood cell count (WBC) and neutrophil count is a well-described phenomenon in persons of African ancestry, whose etiology remains unknown. We recently used admixture mapping to identify an approximately 1-megabase region on chromosome 1, where ancestry status (African or European) almost entirely accounted for the difference in WBC between African Americans and European Americans. To identify the

David Reich; Michael A. Nalls; W. H. Linda Kao; Ermeg L. Akylbekova; Arti Tandon; Nick Patterson; James Mullikin; Wen-Chi Hsueh; Ching-Yu Cheng; Josef Coresh; Eric Boerwinkle; Man Li; Alicja Waliszewska; Julie Neubauer; Rongling Li; Tennille S. Leak; Lynette Ekunwe; Joe C. Files; Cheryl L. Hardy; Joseph M. Zmuda; Herman A. Taylor; Elad Ziv; Tamara B. Harris; James G. Wilson

2009-01-01

320

Reduced neutrophil count in people of African descent is due to a regulatory variant in the Duffy antigen receptor for chemokines gene  

Microsoft Academic Search

Persistently low white blood cell count (WBC) and neutrophil count is a well-described phenomenon in persons of African ancestry, whose etiology remains unknown. We recently used admixture mapping to identify an approximately 1-megabase region on chromosome 1, where ancestry status (African or European) almost entirely accounted for the difference in WBC between African Americans and European Americans. To identify the

David Reich; Michael A. Nalls; W. H. Linda Kao; Ermeg L. Akylbekova; Arti Tandon; Nick Patterson; James Mullikin; Wen-Chi Hsueh; Ching-Yu Cheng; Josef Coresh; Eric Boerwinkle; Man Li; Alicja Waliszewska; Julie Neubauer; Rongling Li; Tennille S. Leak; Lynette Ekunwe; Joe C. Files; Cheryl L. Hardy; Joseph M. Zmuda; Herman A. Taylor; Elad Ziv; Tamara B. Harris; James G. Wilson

2009-01-01

321

SOME PHYSIOLOGIC BLOOD VALUES OF WILD DIVING DUCKS  

Microsoft Academic Search

Blood samples were obtained from 54 canvasbacks (Ayt\\/zya valisineria), 30 lesser scaup (A. a\\/f mis), 3 ring-necks (A. collaris), and 3 buffieheads (Bucephala albeola), which were wintering on Chesapeake Bay. These blood samples were used for: red blood cell counts (cans. 2.56 x 10\\/mm3; scaup 2.45 x 10\\/mm3; ring-necks 2.50 x 10\\/mm; buffiehead 2.64 x 10\\/mm1), packed cell volume (cans.

RICHARD M. KOCAN

322

Somatic cell counts of ewes' milk.  

PubMed

The somatic cell counts of ewes' milk were determined by an electronic particle counter (Coulter Counter). Of 1408 apparently normal milk samples, 98.2% had a somatic cell count lower than 1.0 x 10(6) cells/ml and 85.8% of 254 bacteriologically positive samples had a count higher than 1.0 x 10(6) cells/ml. Values exceeding 1.0 x 10(6) cells/ml are indicative of subclinical mastitis, if samples were collected from clinically healthy mammary glands. PMID:1777802

Fthenakis, G C; el-Masannat, E T; Booth, J M; Jones, J E

1991-01-01

323

Diagnostic Value of Fetal Movement Counting by Mother and the Optimal Recording Duration  

PubMed Central

Introduction: Fetal movement counting is a method used by mother to quantify her baby's movements. However, the optimal number of movements and the ideal duration of counting them have not been recognized. The aim of this study was to determine the diagnostic value of the two common fetal movements counting methods by mother including "ten fetal movements counting in two hours" and "three fetal movements counting in one hour" and to compare the required mean time for counting fetal movements in the two methods. Methods: 300 subjects were selected by random sampling among clients with complains of decreased fetal movements referring to AL-Zahra teaching hospital in Tabriz, Iran. Full training about how to perform the two methods of fetal movements counting and how to record in related tables was instructed by researcher. Immediately after counting movements, biophysical profile test was performed. Results: Among 291 mothers in the two groups, 99.7% had active fetuses based on both methods of fetal movement counting. 96.9% of these active fetuses obtained score of 10 in biophysical profile. There was a statistically significant relation between the results of both two methods of fetal movement counting and the biophysical profile as the gold standard. Sensitivity, specificity, positive and negative predictive values of both methods were equally 100%, 96%, 10% and 100%, respectively.Mean time (SD) for ten movement counting was 22.1(4.6) and for three movementcounting was 8.0(2.8) minutes Conclusion: The findings of this study showed that fetal movement counting test can be used as an initial screening method in predicting fetal health.

Kamalifard, Mahin; Abbasalizadeh, Shamsi; Ghojazadeh, Morteza; Ghatreh Samani, Fatemeh; Rabiei, Leila

2013-01-01

324

Estimating departure times from traffic counts using dynamic assignment  

SciTech Connect

A dynamic traffic assignment algorithm and observed traffic counts are used to estimate the distribution of departure times in a trip matrix. The objective is to find the maximum entropy distribution of departure times by origin zone subject to observed traffic counts on a subset of network links. The procedure results in the estimated number of trip departures from each origin in 10-15 minute time intervals of the full analysis period. Such an analysis period will typically range from one to three hours long. We first review the dynamic assignment algorithm developed and tested in a previous paper, and then describe its use with traffic counts to estimate the departure times of a trip matrix. We present an application to a Pittsburgh network in which trip departures are estimated for each 10-minute interval of a peak-hour survey trip matrix. Computational advances such as parallel computing will enable the procedure to be run on large networks while counts are being monitored. Such an application may provide near real-time detection of temporal trip departure profiles by origin zone. 19 refs., 1 fig., 2 tabs.

Janson, B.N.; Southworth, F. (Oak Ridge National Lab., TN (USA))

1989-07-01

325

FULL ARTICLE Heterodyne detected nonlinear optical imaging  

E-print Network

signal to noise ratio allowed epi-detected in vivo imaging of myelin and blood in rat spinal cordFULL ARTICLE Heterodyne detected nonlinear optical imaging in a lock-in free manner Mikhail N, stimulated Raman scattering, nonlinear microscopy, heterodyne detection Ã? Supporting information

Cheng, Ji-Xin

326

Full Scale Tunnel model  

NASA Technical Reports Server (NTRS)

Interior view of Full-Scale Tunnel (FST) model. (Small human figures have been added for scale.) On June 26, 1929, Elton W. Miller wrote to George W. Lewis proposing the construction of a model of the full-scale tunnel . 'The excellent energy ratio obtained in the new wind tunnel of the California Institute of Technology suggests that before proceeding with our full scale tunnel design, we ought to investigate the effect on energy ratio of such factors as: 1. small included angle for the exit cone; 2. carefully designed return passages of circular section as far as possible, without sudden changes in cross sections; 3. tightness of walls. It is believed that much useful information can be obtained by building a model of about 1/16 scale, that is, having a closed throat of 2 ft. by 4 ft. The outside dimensions would be about 12 ft. by 25 ft. in plan and the height 4 ft. Two propellers will be required about 28 in. in diameter, each to be driven by direct current motor at a maximum speed of 4500 R.P.M. Provision can be made for altering the length of certain portions, particularly the exit cone, and possibly for the application of boundary layer control in order to effect satisfactory air flow.

1929-01-01

327

Shadow Count 2013 Decoy Registration Form  

E-print Network

of the DHS annual count of homeless individuals. Placing decoys throughout the 5 boroughs of NYC (including you ever been homeless? Yes No Add additional information if desired: Are you currently homeless? Yes

Qiu, Weigang

328

Grade 5: Data Analysis: Fundamental Counting Principle  

NSDL National Science Digital Library

In this grade 5 probability supplement students find the probability of simple compound events by creating charts and tree diagrams, and utilizing the fundamental counting principle. The supplement includes one whole group activity, two independent activities, and guide questions.

2013-01-01

329

Low cost crowd counting using audio tones  

E-print Network

With mobile devices becoming ubiquitous, collaborative applications have become increasingly pervasive. In these applications, there is a strong need to obtain a count of the number of mobile devices present in an area, ...

Kannan, Pravein Govindan

330

Objects Counted by the Central Delannoy Numbers  

NASA Astrophysics Data System (ADS)

The central Delannoy numbers, d_n_{n >=0} = 1,3,13,63,321, 1683, 8989, 48639, ... (A001850 of The On-Line Encyclopedia of Integer Sequences) will be defined so that d_n counts the lattice paths running from (0,0) to (n,n) that use the steps (1,0), (0,1), and (1,1). In a recreational spirit we give a collection of 29 configurations that these numbers count.

Sulanke, Robert A.

2003-03-01

331

OBJECTS COUNTED BY THE CENTRAL DELANNOY NUMBERS  

Microsoft Academic Search

The central Delannoy numbers, (dn)n‚0 = 1;3;13;63;321;1683;8989;48639; : : : (A001850 of The On-Line Encyclopedia of Integer Sequences) will be deflned so that dn counts the lattice paths running from (0;0) to (n; n) that use the steps (1;0), (0;1), and (1;1). In a recreational spirit we give a collection of 29 conflgurations that these numbers count.

ROBERT A. SULANKE

332

Total lymphoid irradiation in multiple sclerosis: blood lymphocytes and clinical course  

SciTech Connect

We have found a significant relationship between blood lymphocyte count and prognosis in 45 patients receiving either total lymphoid irradiation or sham irradiation for chronic progressive multiple sclerosis. Patients with sustained lymphocyte counts less than 900 mm-3 for prolonged periods after treatment showed less rapid progression over the ensuing 3 years than did patients with multiple sclerosis who had lymphocyte counts above this level (p less than 0.01). Our results suggest that a simple laboratory test, the absolute blood lymphocyte count, may serve as a valuable barometer for monitoring the amount of immunosuppressive therapy needed to prevent progression in patients with multiple sclerosis, and possibly other autoimmune diseases.

Cook, S.D.; Devereux, C.; Troiano, R.; Zito, G.; Hafstein, M.; Lavenhar, M.; Hernandez, E.; Dowling, P.C.

1987-11-01

333

Medical Laboratory Technician--Hematology, Serology, Blood Banking, and Immunohematology (AFSC 90470).  

ERIC Educational Resources Information Center

This three-volume student text is designed for use by Air Force personnel enrolled in a self-study extension course for medical laboratory technicians. Covered in the individual volumes are hematology (the physiology of blood, complete blood counts and related studies, erythrocyte studies, leukocyte and thrombocyte maturation, and blood

Thompson, Joselyn H.

334

LIBS and LIFS for rapid detection of Rb traces in blood  

Microsoft Academic Search

Tests that can quickly and efficiently detect traces of illegal performance enhancing drugs are becoming essential. Certain performance enhancing drugs lead to an increase in the count of red blood cells. The proportion of blood made up of red cells is normally around 42 percent. At least 90 percent of Rubidium measured in whole blood is located in the red

Mohammad O. Al-Jeffery; Helmut H. Telle

2002-01-01

335

Counting by 10's with Zero the Hero and Little Count  

NSDL National Science Digital Library

In this lesson students will learn to count to 100 by 10's. The relationship between the numbers 1-10 and 10-100 will be made using the 100's chart followed by a power point story about Little Count the Caterpillar. Students will make their own Little Count the Caterpillar using circle body segments, where each circle represents the numerals 10, 20, 30...

Shannon, Darbianne

2012-07-13

336

20 CFR 418.3410 - Whose resources do we count?  

Code of Federal Regulations, 2011 CFR

...2011-04-01 2011-04-01 false Whose resources do we count? 418.3410 Section 418.3410...MEDICARE SUBSIDIES Medicare Part D Subsidies Resources § 418.3410 Whose resources do we count? (a) We count your...

2011-04-01

337

20 CFR 418.3410 - Whose resources do we count?  

Code of Federal Regulations, 2010 CFR

...2010-04-01 2010-04-01 false Whose resources do we count? 418.3410 Section 418.3410...MEDICARE SUBSIDIES Medicare Part D Subsidies Resources § 418.3410 Whose resources do we count? (a) We count your...

2010-04-01

338

Automated TIMI frame counting using 3-d modeling.  

PubMed

Three dimensional coronary modeling and reconstruction can assist in the quantitative analysis of coronary flow velocity from 2-d coronary images. In this paper a novel method to assess coronary flow velocity is proposed. First, 3-d models of the coronary arteries are estimated from bi-plane X-ray images using epipolar constraint energy minimization for the selected fiducial points like bifurcations, and subsequently 3-d B-spline energy minimization for the arterial segments. A 4-d model is assembled from a set of 3-d models representing different phases of the cardiac cycle. The 4-d model is fitted to the 2-d image sequences containing basal or hyperemic blood flow information. Then, by counting the frames in analogy with TIMI frame counting, an index of the mean coronary flow velocity can be estimated. Our experimental results show that the algorithm correlates with r=0.98 (P<0.0001, 95% CI 0.92-0.99) to the clinical measurements of the TFC. PMID:22867533

ten Brinke, G A; Slump, C H; Stoel, M G

2012-10-01

339

Direct determination of internal radiation dose in human blood  

E-print Network

The purpose of this study is to measure the internal radiation dose using a human blood sample. In the literature, there is no process that allows the direct measurement of the internal radiation dose received by a person. The luminescence counts from a blood sample having a laboratory-injected radiation dose and the waste blood of the patient injected with a radiopharmaceutical for diagnostic purposes were both measured. The decay and dose-response curves were plotted for the different doses. The doses received by the different blood aliquots can be determined by interpolating the luminescence counts to the dose-response curve. This study shows that the dose received by a person can be measured directly, simply and retrospectively by using only a very small amount of blood sample. The results will have important ramifications for the medicine and healthcare fields in particular. This will also be very important in cases of suspicion of radiation poisoning, malpractice and so on.

Tan?r, Ayse Güne?

2014-01-01

340

High Blood Pressure  

MedlinePLUS

... during light physical activity or exercise. What Is Blood Pressure? Blood pressure is the force of blood ... stated as 120/80. Do You Have High Blood Pressure? One reason to have regular visits to ...

341

Lead levels - blood  

MedlinePLUS

Blood lead levels ... A blood sample is needed. Most of the time blood is typically drawn from a vein located on the ... may be used to puncture the skin. The blood collects in a small glass tube called a ...

342

Types of Blood Donations  

MedlinePLUS

... Staff Our Member Blood Centers Our Partners Donate blood and save someone's future. PUBLICATIONS PRESS ROOM BLOG ... a few different types of blood donation. Whole Blood This is what most individuals think of when ...

343

High blood pressure - infants  

MedlinePLUS

Hypertension - infants ... and blood vessels The health of the kidneys High blood pressure in infants may be due to kidney or ... Bronchopulmonary dysplasia Renal artery stenosis In newborn babies, high blood pressure is often caused by a blood clot in ...

344

Direct determination of radiation dose in human blood  

E-print Network

Our purpose is to measure the internal radiation dose (ID) using human blood sample. In the literature, there is no process that allows the direct measurement of ID received by a person. This study has shown that it is possible to determine ID in human blood exposed to internal or external ionizing radiation treatment both directly and retrospectively. OSL technique was used to measure the total dose from the blood sample. OSL counts from the waste blood of the patient injected with a radiopharmaceutical for diagnostic or treatment purposes and from a blood sample having a laboratory-injected radiation dose were both used for measurements. The decay and dose-response curves (DRC) were plotted for different doses. The doses received by different blood aliquots have been determined by interpolating the natural luminescence counts to DRC. In addition, OSL counts from a healthy blood sample exposed to an external radiation source were measured. The blood aliquots were given different 0-200Gy beta doses and their ...

Tanir, Ayse Gunes; Sahiner, Eren; Bolukdemir, Mustafa Hicabi; Koc, Kemal; Meric, Niyazi; Kelec, Sule Kaya

2014-01-01

345

Anaemia and iron status among blood donors in a blood transfusion unit in Malaysia.  

PubMed

Iron deficiency is a major complication of regular blood donation as a result of regular iron loss from each donated blood unit. Ninety-two regular blood donors and 95 first time blood donors attending a hospital-based blood transfusion centre were assessed as to their haematological and iron status by blood counts and serum ferritin levels as an indicator of iron stores. All donors had passed the haemoglobin-screening test using a copper sulphate method prior to blood donation. Ferritin levels were found to be significantly lower among regular blood donors (47.8 mmol/L) as compared to first time blood donors (94.2 mmol/L). Iron deficiency as observed by low ferritin levels was seen in 7.4% of all first time donors as compared to 17.4% in regular donors. Male first time donors showed a low prevalence of iron deficiency but the prevalence significantly increased with regular blood donation. Female first time and regular blood donors however did not show any significant differences in prevalence of iron deficiency, with both groups exhibiting prevalence rates similar to male regular donors. The association between haemoglobin levels and iron deficiency was poor and the copper sulphate-screening test was found insensitive to anaemia with many donors passing the test and donating blood despite being anaemic. It is concluded that a high prevalence of iron deficiency is present among regular male blood donors and all female donors. Besides, the use of the copper sulphate screening test as a sole criterion for anaemia screening should be reviewed. Ferritin measurements should be included in the routine assessment of blood donors especially among regular blood donors. PMID:12887168

Nadarajan, Veera S; Eow, Geok Im

2002-12-01

346

Stability of prepared iodine counting standards  

SciTech Connect

This paper reports that the uses for iodine-125 in the medical sciences are increasing. I-125 is often used to label organic molecules in the performance of radioimmunoassay (RIA) procedures, and it has recently been used in the form of 800-mCi sealed sources employed by bone mineral (density) analyzers in the diagnosis of osteoporosis. These applications of the 59.9-day half-life I-125 incur the need to perform contamination surveys. In the case of the use of I-125 labeled compounds, laboratory benches and floors must be regularly checked for the presence of contamination by counting smear or wipe samples. Where multimillicurie sealed I-125 sources are employed, leak tests must be performed, again by counting smear or wipe samples. The most sensitive method readily available for the measurement of I-125 on these smear samples is scintillation counting with a thin NaI(Tl) detector. The counting system used must be calibrated for I-125 counting efficiency.

McLain, M.E.; Yoon, S.C. (Dept. of Nuclear Engineering, Texas A and M Univ., College Station, TX (US))

1987-05-01

347

Variability analysis in low count rate sources. [in astrophysics  

NASA Technical Reports Server (NTRS)

A method, based on the chi-square statistics, is described for detecting pulselike time variability in low count rate sources observed with photon-counting instruments. This method can be used even in the presence of observational gaps, takes full advantage of the filtering effect due to binning with different bin sizes, and takes into account the arbitrariness introduced by the binning phase. The procedure developed to limit the dependence of the results on the binning phase and ensure statistically correct results is described along with the application of the proposed procedure to a model of a variable source. Monte Carlo simulations are used to show how the method can be used to derive the characteristic variability time scales and that the method is more sensitive than the nonparametric Kolmogorov-Smirnov test in detecting variability to a given confidence level.

Collura, A.; Maggio, A.; Sciortino, S.; Serio, S.; Vaiana, G. S.

1987-01-01

348

Decreased plasma cytokines associate with low platelet counts in aplastic anemia and immune thrombocytopenic purpura  

PubMed Central

Summary Background We previously found plasma levels of CD40 ligand (CD40L), chemokine (C-X-C motif) ligand 5 (CXCL5), chemokine (C-C motif) ligand 5 (CCL5), and epidermal growth factor (EGF) to be low in aplastic anemia (AA) patients and to be correlated with the platelet count. Objectives To study the association of CD40L, CXCL5, CCL5, and EGF with platelets. Patients/Methods We measured cytokines in the plasma of immune thrombocytopenic purpura (ITP) and AA patients using the Luminex assay and confirmed the results in a mouse model and in vitro experiments. Results Both ITP and AA showed similarly low levels of CD40L, CXCL5, CCL5, and EGF, compared with healthy controls. In ITP, levels of these proteins were significantly greater in patients with higher platelet counts than in those with lower platelet counts. In a murine thrombocytopenia model, levels of CD40L, CXCL5, CCL5, and EGF decreased with platelet count after immune-mediated destruction, while the cytokine levels increased when the platelet count recovered. In vitro, concentrations of these cytokines in the supernatants of platelet suspensions were proportional to platelet numbers, and levels in sera prepared by simple blood coagulation were equivalent to those in platelet-rich plasma-converted sera. mRNA expression for CXCL5, CCL5, and EGF was higher in platelets than in megakaryocytes, peripheral blood mononuclear cells, granulocytes, and non-megakaryocytic bone marrow cells. Conclusions Plasma CD40L, CXCL5, CCL5, and EGF are mainly platelet-derived, suggesting a role of platelets in immune responses and inflammation. Measurement of CD40L, CXCL5, CCL5, and EGF in human blood allowed testable inferences concerning physiology and pathophysiology in quantitative platelet disorders. PMID:22537155

Feng, Xingmin; Scheinberg, Phillip; Samsel, Leigh; Rios, Olga; Chen, Jichun; McCoy, J. Philip; Ghanima, Waleed; Bussel, James B.; Young, Neal S.

2012-01-01

349

Not everything that counts can be counted: ants use multiple metrics for a single nest trait  

Microsoft Academic Search

There are claims in the literature that certain insects can count. We question the generality of these claims and suggest that summation rather than counting (sensu stricto) is a more likely explanation. We show that Temnothorax albipennis ant colonies can discriminate between potential nest sites with different numbers of entrances. However, our experiments suggest that the ants use ambient light

Nigel R. Franks; Anna Dornhaus; Bonnie G. Metherell; Toby R. Nelson; Sophie A. J. Lanfear; William S. Symes

2006-01-01

350

HIV-1 outcompetes HIV-2 in dually infected Senegalese individuals with low CD4+ cell counts  

PubMed Central

Objective Dual infection with HIV-1 and HIV-2, which is not uncommon in West Africa, has implications for transmission, progression, and antiretroviral therapy (ART). Few studies have examined viral dynamics in this setting. Our objective was to directly compare HIV-1 and HIV-2 viral loads and to examine whether this relationship is associated with CD4+ cell count. Study design This is a retrospective analysis of data from observational cohort studies. Methods We compared HIV-1 and HIV-2 viral loads from 65 dually infected, ART-naive Senegalese individuals. Participants provided blood, oral fluid, and cervicovaginal lavage (CVL) or semen samples for virologic and immunologic testing. We assessed relationships between HIV-1 and HIV-2 levels using linear regression with generalized estimating equations to account for multiple study visits. Results After adjusting for CD4+ cell count, age, sex, and commercial sex work, HIV-1 RNA levels were significantly higher than HIV-2 levels in semen, CVL, and oral fluids. Despite similar peripheral blood mononuclear cell DNA levels among individuals with CD4+ cell counts above 500 cells/µl, individuals with CD4+ cell counts below 500 cells/µl had higher HIV-1 and lower HIV-2 DNA levels. Individuals with high CD4+ cell counts had higher mean HIV-1 plasma RNA viral loads than HIV-2, with HIV-1 levels significantly higher and HIV-2 levels trending toward lower mean viral loads among individuals with low CD4+ cell counts. Conclusion Our data are consistent with the hypothesis that with disease progression, HIV-1 outcompetes HIV-2 in dually infected individuals. This finding helps explain differences in prevalence and outcomes between HIV-1, HIV-2, and HIV-dual infection. PMID:23665777

Raugi, Dana N.; Gottlieb, Geoffrey S.; Sow, Papa S.; Toure, Macoumba; Sall, Fatima; Gaye, Awa; N'doye, Ibra; Kiviat, Nancy B.; Hawes, Stephen E.

2014-01-01

351

Measures of Child Well-Being in Utah, 2002: Counting the Kids Who Count on Us. Utah KIDS COUNT.  

ERIC Educational Resources Information Center

This Kids Count report details statewide trends in the well-being of Utah's children. The statistical portrait is based on 29 indicators of children's well-being in five areas: (1) child health and safety (prenatal care, low birthweight, infant mortality, child injury deaths, injury-related hospital discharges, child abuse, childhood…

Haven, Terry, Ed.

352

Estimating Pedestrian Accident Exposure: Automated Pedestrian Counting Devices Report  

Microsoft Academic Search

Automated methods are commonly used to count motorized vehicles, but are not frequently used to count pedestrians. This is because the automated technologies available to count pedestrians are not very developed, and their effectiveness has not been widely researched. Moreover, most automated methods are used primarily for the purpose of detecting, rather than counting, pedestrians (Dharmaraju et al., 2001; Noyce

Fanping Bu; Ryan Greene-Roesel; Mara Chagas Diogenes; David R Ragland

2007-01-01

353

Effect of herbal biostimulators on rumen liquor, blood and milk constituents of lactating cows  

E-print Network

Effect of herbal biostimulators on rumen liquor, blood and milk constituents of lactating cows CS protozoal count of rumen liquor was determined by the method of Naga and EI-Shazly (1969, J Dairy Res, 36, 1

Boyer, Edmond

354

Effect of measurement duration on accuracy of pulse-counting  

PubMed Central

In this study, the relation between the measurement duration and accuracy of pulse-counting was quantitatively examined with special reference to low-frequency fluctuations in heart rate variability. The interbeat intervals of 70 healthy male subjects were measured in standing, sitting and supine positions. Pulse rates for various durations were calculated by objective-scoring simulation based on the heartbeat recordings of the subjects. The duration of pulse-counting continuously varied from 6 to 60 s in the simulation. Simulated pulse rates were compared with the rate calculated from the 60 s that includes the given duration, and the absolute difference between the two rates was defined as the error. Average errors of pulse-counting for 15 s were 1.89, 1.89 and 1.80 bpm for standing, sitting and supine positions, respectively. No difference in error was observed between standing and sitting positions; however, smaller errors were observed in the supine position. Practitioner Summary: This study provides information on the degree of error that will occur when pulse rates are objectively scored for various durations, for example 10, 15 or 30 s, instead of a full minute. This useful information may be beneficial for physicians, nurses and medical practitioners. PMID:24117167

Kobayashi, Hiromitsu

2013-01-01

355

Virginia KIDS COUNT Data Book, 2003.  

ERIC Educational Resources Information Center

This Kids Count data book details statewide trends in the well-being of Virginia's children. The statistical portrait is based on indicators of child well-being in five areas: healthy births, adolescent well-being, health and safety, education, and economic security. Specific indicators examined are: (1) births to single women; (2) early prenatal…

2003

356

Montana Kids Count 1996 Data Book.  

ERIC Educational Resources Information Center

This 1996 KIDS COUNT data book presents comparative data on child well-being for each county in Montana and for the state as a whole. Data in the county profiles, which comprise the bulk of the report, are grouped into: background facts (demographic, mental health, education, security, and income support information); charts showing changes in…

Healthy Mothers, Healthy Babies--The Montana Coalition, Helena.

357

Kids Count in Indiana: 1994 Data Book.  

ERIC Educational Resources Information Center

This booklet provides data on a series of related measures of child and family well-being in Indiana, following national guidelines established by the Kids Count project to help Americans better understand the problems faced by children and adolescents and to foster greater commitment to improving outcomes for vulnerable children and their…

Erickson, Judith B.

358

Rhode Island Kids Count Factbook, 2003.  

ERIC Educational Resources Information Center

This KIDS COUNT databook is the eighth annual profile examining statewide trends in the well-being of Rhode Island's children. The statistical portrait is based on 53 indicators (3 new indicators in this databook) in 5 areas: (1) family and community (including child population, children in single parent families, and racial and ethnic diversity);…

Rhode Island KIDS COUNT, Providence.

359

Rhode Island KIDS COUNT Factbook, 2002.  

ERIC Educational Resources Information Center

This KIDS COUNT databook is the seventh annual profile examining statewide trends in the well-being of Rhode Island's children. The statistical portrait is based on 49 indicators (6 new indicators in this databook) in 5 areas: (1) family and community (including child population, children in single parent families, and racial and ethnic…

Rhode Island KIDS COUNT, Providence.

360

Kids Count in Nebraska: 1995 Report.  

ERIC Educational Resources Information Center

While a vast majority of children in Nebraska are experiencing a safe, healthy, and nurturing childhood, a significant number are not, and some of these numbers are growing. This Kids Count report is the third annual comprehensive review of available data in nine areas of child health and well-being in the state. Presented with these statistics…

Nebraska Univ. Medical Center, Omaha.

361

Counting Abelian Squares L. B. Richmond  

E-print Network

Counting Abelian Squares L. B. Richmond Department of Combinatorics and Optimization University of Waterloo Waterloo, ON N2L 3G1 Canada lbrichmo@math.uwaterloo.ca Jeffrey Shallit School of Computer Science University of Waterloo Waterloo, ON N2L 3G1 Canada shallit@cs.uwaterloo.ca July 31, 2008 Abstract An abelian

Shallit, Jeffrey O.

362

Radionuclide Counting Technique Measures Wind Velocity  

NASA Technical Reports Server (NTRS)

Proposed technique for measuring wind velocity based on inverse-squarelaw variation of radioactive counting rates. In proposal, radioative source is deposited on bottom of light, hollow sphere and suspended by flexible wire over radiation counter, Anemometer based on this concept is self-contained, portable, yet not too fragile. Used for extended periods of time, even at remote, inhospitable and inaccessible sites.

Singh, J. J.; Khandelwal, G. S.; Mall, G. H.

1983-01-01

363

County Data Book 1997: Kentucky Kids Count.  

ERIC Educational Resources Information Center

This Kids Count data book examines trends in the well-being of Kentucky's children on a statewide and county basis. An introduction summarizes some of the trends for Kentucky's children in the 1990s. The bulk of the report presents statewide and county data grouped into five categories: (1) poverty rates and programs (persons in poverty; median…

Kentucky Kids Count Consortium.

364

KIDS COUNT in Virginia, 2001 [Data Book].  

ERIC Educational Resources Information Center

This Kids Count data book details statewide trends in the well-being of Virginia's children. The statistical portrait is based on the following four areas of children's well-being: health and safety; education; family; and economy. Key indicators examined are: (1) prenatal care; (2) low birth weight babies; (3) infant mortality; (4) child abuse or…

Action Alliance for Virginia's Children and Youth, Richmond.

365

Kids Count in Missouri 1998 Data Book.  

ERIC Educational Resources Information Center

This Kids Count data book examines statewide trends in the well-being of Missouri's children. The statistical portrait is based on outcome measures of general areas of children's well being: (1) students free/reduced price lunch program; (2) births to mothers without high school diplomas; (3) low birthweight infants; (4) infant mortality; (5)…

Citizens for Missouri's Children, St. Louis.

366

South Dakota Kids Count Factbook, 2001.  

ERIC Educational Resources Information Center

This Kids Count factbook examines statewide trends in well-being for South Dakota's children. The statistical portrait is based on 24 indicators in the areas of demographics, health, education, economic status, and safety. The indicators are: (1) poverty thresholds; (2) population; (3) population on Indian Reservations; (4) infant mortality; (5)…

Cochran, Carole, Ed.

367

KIDS COUNT in Virginia: 1997 Data Book.  

ERIC Educational Resources Information Center

This KIDS COUNT data book examines statewide trends in the well-being of Virginia's children. The statistical portrait is based on six general areas of children's well-being: (1) healthy births; (2) children's health; (3) school success; (4) risky behavior; (5) families; and (6) community well-being. Key indicators in these six areas include the…

Galano, Joseph; Nezlek, John B.; Wood, Lisa

368

Maine KIDS COUNT 2000 Data Book.  

ERIC Educational Resources Information Center

This KIDS COUNT Report details statewide trends in the well-being of Maine's children. The statistical portrait is based on a variety of indicators in the areas of: (1) physical and mental health; (2) social and economic opportunity; (3) education and learning; and (4) child health care access. The report contains a special section on Maine…

Maine Children's Alliance, Augusta.

369

Maine Kids Count 1997 Data Book.  

ERIC Educational Resources Information Center

This Kids Count report details statewide trends in the well-being of Maine's children. The statistical portrait is based on indictors children's well-being in four areas: (1) physical and mental health; (2) social and economic opportunity; (3) community and family environment; and (4) education and learning. The report's introduction describes…

Maine Children's Alliance, Augusta.

370

Fast box-counting algorithm on GPU.  

PubMed

The box-counting algorithm is one of the most widely used methods for calculating the fractal dimension (FD). The FD has many image analysis applications in the biomedical field, where it has been used extensively to characterize a wide range of medical signals. However, computing the FD for large images, especially in 3D, is a time consuming process. In this paper we present a fast parallel version of the box-counting algorithm, which has been coded in CUDA for execution on the Graphic Processing Unit (GPU). The optimized GPU implementation achieved an average speedup of 28 times (28×) compared to a mono-threaded CPU implementation, and an average speedup of 7 times (7×) compared to a multi-threaded CPU implementation. The performance of our improved box-counting algorithm has been tested with 3D models with different complexity, features and sizes. The validity and accuracy of the algorithm has been confirmed using models with well-known FD values. As a case study, a 3D FD analysis of several brain tissues has been performed using our GPU box-counting algorithm. PMID:22917763

Jiménez, J; Ruiz de Miras, J

2012-12-01

371

Mining Large Networks with Subgraph Counting  

Microsoft Academic Search

The problem of mining frequent patterns in networks has many applications, including analysis of complex networks, clustering of graphs, finding communities in social networks, and indexing of graphical and biological databases. Despite this wealth of applications, the current state of the art lacks algorithmic tools for counting the number of subgraphs contained in a large network. In this paper we

Ilaria Bordino; Debora Donato; Aristides Gionis; Stefano Leonardi

2008-01-01

372

Georgia Kids Count Factbook, 1998-99.  

ERIC Educational Resources Information Center

This Kids Count factbook presents statistical data and examines trends for 10 indicators of children's well-being in Georgia. The indicators are: (1) low birthweight babies; (2) infant mortality; (3) child deaths; (4) teen deaths by accident, homicide, and suicide; (5) juvenile arrests; (6) reading and math scores on the Iowa Test of Basic Skills;…

Georgians for Children, Atlanta, GA.

373

Stalking the count. Dracula, Fandom and Tourism  

Microsoft Academic Search

Large numbers of tourists travel to Transylvania every year, looking for traces of Count Dracula. This article investigates why people feel the need to connect fictional stories, such as Dracula, with identifiable physical locations, and why they subsequently want to visit these locations. Based on field work, it is concluded that the experience of the Dracula tourist is characterised by

S. Reijnders

2011-01-01

374

Ptime Canonization for Two Variables with Counting  

Microsoft Academic Search

We consider infinitary logic with two variable symbolsand counting quantifiers, C2, and its intersectionwith Ptime on finite relational structures. In particularwe exhibit a Ptime canonization procedure forfinite relational structures which provides unique representativesup to equivalence in C2. As a consequencewe obtain a recursive presentation for the class of allthose queries on arbitrary finite relational structureswhich are both Ptime and definable

Martin Otto; RWTH Aachen

1995-01-01

375

Approximate Frequency Counts over Data Streams  

Microsoft Academic Search

We present algorithms for computing frequency counts exceeding a user-specified threshold over data streams. Our algorithms are simple and have provably small memory footprints. Although the output is approximate, the error is guaranteed not to exceed a user-specified parameter. Our algo- rithms can easily be deployed for streams of single- ton items like those found in IP network monitor- ing.

Gurmeet Singh Manku; Rajeev Motwani

2002-01-01

376

KIDS COUNT in Missouri 2000 Data Book.  

ERIC Educational Resources Information Center

This KIDS COUNT data book details statewide trends in the well-being of Missouri's children in the areas of economic security, school success, child health, child safety, and adolescent success. The statistical portrait is based on the following indicators: (1) students enrolled in free/reduced price lunch programs; (2) births to mothers without a…

Citizens for Missouri's Children, St. Louis.

377

Alabama Kids Count 2001 Data Book.  

ERIC Educational Resources Information Center

This Kids Count data book examines statewide trends in well-being for Alabama's children. The statistical portrait is based on 17 indicators in the areas of health, education, safety, and security. The indicators are: (1) infant mortality rate; (2) low weight births; (3) child health index; (4) births to unmarried teens; (5) first grade retention;…

Curtis, Apreill; Bogie, Don

378

KIDS COUNT in Missouri 1999 Data Book.  

ERIC Educational Resources Information Center

This Kids Count Data Book examines statewide trends in the well-being of Missouri's children. The statistical portrait is based on the following indicators of general areas of children's well being: (1) students enrolled in free/reduced price lunch program; (2) births to mothers without a high school diploma; (3) low birth weight; (4) infant…

Citizens for Missouri's Children, St. Louis.

379

Kids Count in Missouri 1997 Data Book.  

ERIC Educational Resources Information Center

This KIDS COUNT report documents the status of children in all 115 Missouri counties. Following an executive summary that reports areas of improvement, stabilization, and deterioration, and profiles for the state as a whole and for Caucasians versus minorities, summary information is provided for the following indicators: (1) students enrolled in…

Citizens for Missouri's Children, St. Louis.

380

Kids Count in Delaware: Fact Book, 1997.  

ERIC Educational Resources Information Center

This KIDS COUNT report details statewide trends in the well-being of Delaware's children. The statistical profile is based on 10 main indicators of child well-being: (1) births to teens; (2) low birth weight babies; (3) infant mortality; (4) child deaths, age 1-14 years; (5) teen violent deaths by accident, homicide, and suicide; (6) juvenile…

Dowshen, Steven, Ed.; Greback, Robert, Ed.; Nelson, Carl, Ed.; Schooley, Teresa L., Ed.; Sturgis, Janice, Ed.

381

KIDS COUNT in Missouri 1994 Report.  

ERIC Educational Resources Information Center

This KIDS COUNT report examines statewide trends in the well-being of Missouri's children. The statistical portrait is organized by county and is based on 11 outcome measures of children's well-being: (1) students enrolled in free/reduced lunch programs; (2) births to mothers without high school diplomas; (3) low birthweight infants; (4) infant…

Citizens for Missouri's Children, St. Louis.

382

KIDS COUNT in Missouri 1995 Report.  

ERIC Educational Resources Information Center

This KIDS COUNT report examines statewide trends in the well-being of Missouri's children. The statistical portrait is organized by county and is based on 10 outcome measures of children's well-being: (1) students enrolled in free/reduced lunch programs; (2) births to mothers without high school diplomas; (3) low birthweight infants; (4) infant…

Citizens for Missouri's Children, St. Louis.

383

Alabama Kids Count 2002 Data Book.  

ERIC Educational Resources Information Center

This Kids Count data book examines statewide trends in well-being of Alabamas children. The statistical portrait is based on 18 indicators in the areas of child health, education, safety, and security: (1) infant mortality rate; (2) low weight births; (3) child health index; (4) births to unmarried teens; (5) first grade retention; (6) school…

Curtis, Apreill; Bogie, Don

384

WisKids Count Data Book, 2001.  

ERIC Educational Resources Information Center

This WisKids Count data book provides a statistical portrait of K-12 education in the state of Wisconsin. The introduction to the data book examines financing of education, including special education, and the issue of financing private education with public dollars; barriers to school success, including mobility and racial disparities; what…

Townsend, Laura; Grigsby, Tamera; Peacock, Jon; Brien, Nan

385

Rhode Island Kids Count Factbook, 2000.  

ERIC Educational Resources Information Center

This KIDS COUNT databook is the sixth annual profile examining statewide trends in the well-being of Rhode Island's children. The statistical portrait is based on 37 indicators in 5 areas: (1) family and community (covering child population and children in single-parent families); (2) economic well-being (covering median household income, cost of…

Rhode Island KIDS COUNT, Providence.

386

Rhode Island Kids Count Factbook, 1999.  

ERIC Educational Resources Information Center

This KIDS COUNT databook is the fifth annual profile examining statewide trends in the well-being of Rhode Island's children. The statistical portrait is based on 30 indicators in 5 areas: (1) family and community (covering child population and children in single-parent families); (2) economic well-being (covering median household income, cost of…

Rhode Island KIDS COUNT, Providence.

387

Rhode Island KIDS COUNT Factbook, 1997.  

ERIC Educational Resources Information Center

This Kids Count report examined statewide trends in the well-being of Rhode Island's children. Five chapters addressed the areas of: family and community; economic well-being; child health; safety; and education. The statistical portrait is based on 26 indicators of well-being: (1) children in single parent families; (2) median household income;…

Bryant, Elizabeth Burke, Ed.; And Others

388

Rhode Island Kids Count Factbook, 2001.  

ERIC Educational Resources Information Center

This Kids Count databook is the seventh annual profile examining statewide trends in the well-being of Rhode Island's children. The statistical portrait is based on 43 indicators in 5 areas: (1) family and community (including child population and children in single-parent families); (2) economic well-being (including median household income,…

Rhode Island KIDS COUNT, Providence.

389

Some counting problems related to permutation groups  

E-print Network

of the problem of counting the orbits of an infinite per- mutation group on n-sets or n-tuples, especially for each cardinality k of hyperedges. The age of M, written Age (M), is the class of all finite by Fra"iss'e [7], who says that the structure M is younger than N if the age of M is contained

Cameron, Peter

390

Kids Count in Nebraska 1996 Report.  

ERIC Educational Resources Information Center

This Kids Count report examines statewide trends in the well-being of Nebraska's children. The statistical portrait is based on seven general areas of children's well-being: (1) early care and education; (2) physical and behavioral health; (3) child abuse, neglect, and domestic violence; (4) out of home care; (5) education; (6) economic…

Voices for Children in Nebraska, Omaha.

391

Maine KIDS COUNT 2001 Data Book.  

ERIC Educational Resources Information Center

This KIDS COUNT data book details statewide trends in the well-being of Maine's children. The statistical portrait is based on a variety of indicators in the areas of: (1) physical and mental health; (2) social and economic opportunity; (3) education and learning; and (4) child health care access. The data book presents state level trend data, a…

Davey, Lynn

392

County Data Book 1996: Kentucky Kids Count.  

ERIC Educational Resources Information Center

This Kids Count data book examines trends in the well-being of Kentucky children on a state-wide, county, and school district basis. An introductory essay finds a strong link between the percentage of adults completing high school in a given school district and various indicators: As the percentage of adults completing high school increases, the…

Kentucky Youth Advocates, Inc., Louisville.

393

Maine Kids Count 1999 Data Book.  

ERIC Educational Resources Information Center

This Kids Count Report details statewide trends in the well-being of Maine's children, with particular focus on child health care access. The statistical portrait is based on a variety of indicators in five areas: (1) child health care access; (2) physical and mental health; (3) community and family environment; (4) social and economic…

Maine Children's Alliance, Augusta.

394

County Data Book 1995: Kentucky Kids Count.  

ERIC Educational Resources Information Center

This data book presents findings of the Kids Count project on current conditions faced by Kentucky children age birth through 19. For each county, and for the state, comparisons are provided between the base years of 1980-1982 and the most recent years 1992-1994. Counties are ranked against each other and trend graphs are provided for the studied…

Kentucky Youth Advocates, Inc., Louisville.

395

Kansas Kids Count Data Book, 1996.  

ERIC Educational Resources Information Center

This 1996 Kids Count data book presents data on 20 indicators of child well-being in Kansas, grouped into 6 areas: economic well-being, physical health and safety, educational achievement, early childhood care and education, emotional well-being, and social behavior and social control. The data are grouped by county for each indicator, by…

Kansas Action for Children, Inc., Topeka.

396

Kids Count in Delaware: Fact Book, 1995.  

ERIC Educational Resources Information Center

This Kids Count fact book examines statewide trends in the well-being of Delaware's children. The statistical portrait is based on key indicators in four areas: single-parent families, births to teenage mothers, juvenile crime and violence, and education. Following brief sections on the state's demographics and economic status, the fact book…

Delaware Univ., Newark. Kids Count in Delaware.

397

Going Online to Make Learning Count  

ERIC Educational Resources Information Center

Adult students often come to higher education with college-level learning that they have acquired outside of the classroom--from the workplace, military service, self-study, or hobbies. For decades, many forward-thinking colleges and universities have been offering services to evaluate that learning and award it college credit that counts towards…

Brigham, Cathy; Klein-Collins, Rebecca

2011-01-01

398

Concurrent Cycle Collection in Reference Counted Systems  

Microsoft Academic Search

Automatic storage reclamation via reference counting has important advantages, but has always suffered from a major weakness due to its inability to reclaim cyclic data structures. We describe a novel cycle collection algorithm that is both concurrent — it is capable of collecting garbage even in the presence of simultaneous mutation — and localized — it never needs to perform

David F. Bacon; V. T. Rajan

2001-01-01

399

Rhode Island KIDS COUNT Factbook, 1996.  

ERIC Educational Resources Information Center

This KIDS COUNT report examines statewide trends in the well-being of Rhode Island's children. Five chapters address the areas of family and community, economic well-being, child health, safety, and education. The statistical portrait is based on 23 indicators of well-being: (1) children in single parent families; (2) median household income; (3)…

Rhode Island KIDS COUNT, Providence.

400

Kids Count in Nebraska: 2001 Report.  

ERIC Educational Resources Information Center

This Kids Count report examines statewide trends and county data on the well-being of Nebraska's children. Section 1 contains a commentary on promoting quality early childhood care and education services. Section 2, the bulk of this statistical report, presents finding on indicators of well-being in eight areas: (1) child abuse and…

Johnston, Janet M.

401

Kids Count in Nebraska: 1999 Report.  

ERIC Educational Resources Information Center

This Kids Count report is the seventh to examine statewide trends and county data on the well-being of Nebraska's children. The bulk of this statistical report presents findings on indicators of well-being in eight areas: (1) child abuse and neglect/domestic violence (investigated and substantiated cases, who reports, types of abuse, domestic…

Johnston, Janet M.

402

Kids Count in Nebraska: 2000 Report.  

ERIC Educational Resources Information Center

This Kids Count report examines statewide trends and county data on the well-being of Nebraska's children. Section 1 contains a commentary on juvenile justice in Nebraska. Section 2, the bulk of this statistical report, presents findings on indicators of well-being in eight areas: (1) child abuse and neglect/domestic violence (investigated and…

Johnston, Janet M.

403

Success in School: Education Ideas that Count.  

ERIC Educational Resources Information Center

The Kids Count project is an effort to track the status of children in the United States by providing policymakers and citizens with national and state benchmarks of well-being. This multi-publication packet describes the project and several factors that increase the likelihood of children's academic success. The first of two pamphlets, the "Kids…

Annie E. Casey Foundation, Baltimore, MD.

404

An efficient filling algorithm for counting regions  

Microsoft Academic Search

Region filling has many applications in computer graphics and image analysis. Some region filling tasks can be performed by fast scan line filling algorithms. Other region filling tasks require seed filling algorithms which are more general but slower. This paper introduces a seed filling algorithm that is designed to count regions irrespective of their shape. The method is described and

Wil G. M. Geraets; A. N. Van Daatselaar; J. G. C. Verheij

2004-01-01

405

Chimpanzee counting and rhesus monkey ordinality judgments  

NASA Technical Reports Server (NTRS)

An investigation is conducted to address the questions of whether chimpanzees can count and whether rhesus monkeys can differentiate written numbers. One investigation demonstrates the capacity of a chimpanzee to produce a quantity of responses appropriate to a given Arabic numeral. Rhesus monkeys are shown to have the capability for making fine differentiations between quantities of pellets and Arabic numerals.

Rumbaugh, Duane M.; Washburn, David A.; Hopkins, William D.; Savage-Rumbaugh, E. S.

1991-01-01

406

Kansas KIDS COUNT Data Book, 2001.  

ERIC Educational Resources Information Center

This Kids Count Data Book provides state and county trends in the well-being of Kansas' children. The statistical portrait is based on 21 indicators of well-being: (1) births to single teens; (2) children in poverty; (3) children approved for free school meals; (4) childhood deaths; (5) infant mortality; (6) births with early prenatal care; (7)…

Kansas Action for Children, Inc., Topeka.

407

KIDS COUNT in Missouri 2001 Data Book.  

ERIC Educational Resources Information Center

This KIDS COUNT data book details statewide trends in the well-being of Missouri's children in the areas of economic security, school success, child health, child safety, and adolescent success. The statistical portrait is based on the following indicators: (1) students enrolled in free/reduced price lunch programs; (2) births to mothers without a…

Citizens for Missouri's Children, St. Louis.

408

South Carolina Kids Count Report, 2003.  

ERIC Educational Resources Information Center

This Kids Count report examines statewide trends in the well-being of South Carolina's children. The statistical portrait is based on 44 indicators in the areas of demographics, family, economic status, health, readiness and early school performance, scholastic achievement, and adolescent risk behaviors. The indicators are: (1) population; (2)…

South Carolina Kids Count, Columbia.

409

Kentucky Kids Count 2002 County Data Book.  

ERIC Educational Resources Information Center

This Kids Count data book examines statewide trends in the well-being of Kentucky's children. The statistical portrait is based on indicators of child well-being in the areas of: (1) child poverty; (2) family types; (4) child living arrangements and parental employment; (4) births; (5) child and teen deaths; (6) economic security; (7) student…

Salley, Valerie

410

KidsCount in Colorado! 1994.  

ERIC Educational Resources Information Center

This 1994 Kids Count report focuses on risk-taking behaviors among Colorado adolescents and discusses how prevention and early intervention strategies can impact the lives of the state's children. Statistics and descriptions are given for: (1) alcohol, tobacco, and drug use; (2) teen sexuality, including sexual activity and teen pregnancy and…

Buck, Beverly R.

411

Kids Count Alaska Data Book: 1997.  

ERIC Educational Resources Information Center

This second annual Kids Count data book examines statewide trends in the well-being of Alaska's children. The statistical portrait is based on key indicators in six areas: (1) early childhood, including prenatal care, infant mortality, and children with developmental disabilities; (2) economic well-being, including children living in poverty and…

Alaska Univ., Anchorage. Inst. of Social and Economic Research.

412

All Our Children: Massachusetts Kids Count 1994.  

ERIC Educational Resources Information Center

This Kids Count report examines statewide trends from 1990 to 1994 in the well-being of Massachusetts' children. The statistical portrait is based on indicators of well-being in five areas: (1) economic well-being of children and their families, including child poverty rate, family income, job loss, earnings of male high school dropouts and…

Diamond, Franna, Ed.

413

What Counts: Social Accounting for Nonprofits  

Microsoft Academic Search

The papers are based on a recent book, What Counts: Social Accounting for Nonprofits and Co-operatives (Quarter, Mook, & Richmond, 2003), that defines, describes and provides practical models of social accounting statements as well as presenting a toolkit for implementation. The book argues that financial accounting should expand to include social variables using the example of volunteer contributions as a

Jack Quarter; Jorge Sousa; Laurie Mook; Betty Jane Richmond

414

An Introduction to Adults Count Too.  

ERIC Educational Resources Information Center

This paper provides an overview of a book entitled "Adults Count Too: Mathematics for Empowerment". The introduction to the book details why the author spent three years writing about adults learning mathematics, and outlines the shape and structure of the book. A chapter from the book, entitled "A Matrix of Factors," is presented as an example of…

Benn, Roseanne

415

South Dakota Kids Count Factbook, 2000.  

ERIC Educational Resources Information Center

This Kids Count fact book examines statewide trends in well-being for South Dakota's children. The statistical portrait is based on 26 indicators in the areas of demographics, health, education, economic status, and safety. The indicators are: (1) population; (2) family profile; (3) poverty thresholds; (4) infant mortality; (5) low birth weight…

Cochran, Carole

416

South Dakota KIDS COUNT Factbook, 1999.  

ERIC Educational Resources Information Center

This Kids Count fact book examines statewide trends in well-being for South Dakota's children. The statistical portrait is based on 25 indicators in the areas of demographics, health, education, economic status, and safety. The indicators are: (1) population; (2) family profile; (3) poverty thresholds; (4) infant mortality rate; (5) low birth…

Cochran, Carole, Ed.

417

Nevada Kids Count Data Book, 1998.  

ERIC Educational Resources Information Center

This Kids Count report provides information on statewide trends affecting children and families in Nevada. The report is comprised of eight sections: an overview; Nevada's demographic profile; key facts regarding children in the state; Nevada's comparison to the rest of the United States; trends in the state; indicators of child well-being;…

Ford, Paula R.

418

Kids Count in Nebraska: 1998 Report.  

ERIC Educational Resources Information Center

This Kids Count report is the sixth to examine statewide trends and county data on the well-being of Nebraska's children. The bulk of this statistical report presents findings on 32 indicators of well-being in 8 areas: (1) child abuse and neglect/domestic violence, including abuse fatalities and serious injuries; (2) early childhood care and…

Cassatt, Susan

419

Maine Kids Count 1998 Data Book.  

ERIC Educational Resources Information Center

This Kids Count report details statewide trends in the well-being of Maine's children. The statistical portrait is based on indicators of children's well-being in four areas: (1) physical and mental health; (2) community and family environment; (3) social and economic opportunity; and (4) education and learning. The report's introduction describes…

Maine Children's Alliance, Augusta.

420

Kids Count in Nebraska: 1997 Report.  

ERIC Educational Resources Information Center

This Kids Count report is the fifth to examine statewide trends and county data on the well-being of Nebraska's children. The bulk of this statistical report presents findings on 32 indicators of well-being in 8 areas: (1) juvenile justice, including juvenile arrests, and numbers committed to youth rehabilitation and treatment centers; (2)…

Bentz, Cara Anderson

421

Georgia Kids Count Factbook, 2000-2001.  

ERIC Educational Resources Information Center

This Kids Count factbook examines statewide and county trends in the well-being of Georgia's children. The statistical portrait is based on indicators in five domains: family and community, economic well-being, health, education, and safety and security. The 21 indicators of well-being are: (1) child population; (2) public school enrollment; (3)…

Dopkins, Laurie B.; Carter, John; Beavers, Barbara

422

KidsCount in Colorado! 2000.  

ERIC Educational Resources Information Center

This Kids Count report examines statewide and county trends in the well-being of Colorado's children. The statistical portrait is based on 24 indicators of well-being: (1) children receiving AFDC (Aid to Families with Dependent children); (2) children receiving TANF; (3) children qualifying for free lunch; (4) children in out-of-home placements;…

Vasquez, Jenifer

423

Nevada Kids Count Data Book, 1997.  

ERIC Educational Resources Information Center

This Kids Count data book is the first to examine statewide indicators of the well being of Nevada's children. The statistical portrait is based on 15 indicators of child well being: (1) percent low birth-weight babies; (2) infant mortality rate; (3) percent of children in poverty; (4) percent of children in single-parent families; (5) percent of…

We Can, Inc., Las Vegas, NV.

424

KidsCount in Colorado! 1997.  

ERIC Educational Resources Information Center

This 1997 Kids Count report examines challenges to Colorado children and youth and how prevention and early intervention can enhance their well-being. The report includes a summary of recent research on brain development and the importance of early experience and stimulation in early intervention programs. The levels of state funding for various…

Shulman, Shanna

425

KidsCount in Colorado! 2001.  

ERIC Educational Resources Information Center

This Kids Count report examines statewide and county trends in the well-being of Colorado's children. Indicators are presented in the general areas of demographics, abuse and neglect, child health, family issues, and teen issues. The statistical portrait is based on 16 indicators of well-being: (1) confirmed incidents of child abuse and neglect;…

Boeke, Kaye

426

KidsCount in Colorado! 1999.  

ERIC Educational Resources Information Center

This Kids Count report examines statewide and county trends in the well-being of Colorado's children. The statistical portrait is based on 12 indicators of well-being: (1) infant mortality; (2) low birth weight births; (3) immunizations; (4) child poverty; (5) early prenatal care; (6) child abuse deaths; (7) health insurance; (8) paternity…

Staberg, Christine

427

Wilmington Kids Count Fact Book, 2001.  

ERIC Educational Resources Information Center

This Kids Count fact book provides a statistical portrait of the well-being of children in Wilmington, Delaware, and is designed as a resource for policymakers and citizens to use in shaping local action to improve the status of children and families in Wilmington. In addition to demographic information, 11 featured indicators are used to describe…

Delaware Univ., Newark. Kids Count in Delaware.

428

Maine KIDS COUNT 2002 Data Book.  

ERIC Educational Resources Information Center

This KIDS COUNT data book details statewide trends in the well-being of Maine's children. Following a brief overview of the data book and a summary of indicators, state trend data are presented in the areas of: (1) poverty; (2) child and adolescent suicide; (3) public high school dropouts; (4) teen pregnancy; (5) public high school graduates…

Maine Children's Alliance, Augusta.

429

Wyoming Kids Count in Wyoming Factbook, 1999.  

ERIC Educational Resources Information Center

This Kids Count factbook details statewide trends in the well-being of Wyoming's children. Following an overview of key indicators and data sources, the factbook documents trends by county for 20 indicators, including the following: (1) poverty and population; (2) welfare reform; (3) certified day care facilities; (4) births; (5) infant deaths;…

Wyoming Children's Action Alliance, Cheyenne.

430

KidsCount in Colorado! 1998.  

ERIC Educational Resources Information Center

This Kids Count report examines statewide and county trends in the well-being of Colorado's children. The statistical portrait is based on 12 indicators of well-being: (1) infant mortality; (2) low birth weight births; (3) immunizations; (4) child poverty; (5) early prenatal care; (6) child abuse deaths; (7) health insurance; (8) paternity…

Staberg, Christine

431

Vote-counting methods in research synthesis  

Microsoft Academic Search

Reviews of research usually rely on counts of the number of times the treatment group mean exceeds the control group mean by an amount that is statistically significant. The treatment is said to have a positive effect if the proportion of such positive significant results is large. This procedure is shown to have extremely low power for the combination of

Larry V. Hedges; Ingram Olkin

1980-01-01

432

Youth Count: The Vermont Youth Report, 2002.  

ERIC Educational Resources Information Center

This KIDS COUNT report examines trends in the well-being of Vermont's youth. The report balances at-risk youth data with survey results related to "positive youth development," an approach that promotes beneficial attributes of youth and their communities. Following an introduction and discussion of positive youth development and youth well-being…

Farber, Wendy; Burgess, Beth

433

Higher Education Counts: Achieving Results. 2009 Report  

ERIC Educational Resources Information Center

"Higher Education Counts" is the annual accountability report on Connecticut's state system of higher education, as required under Connecticut General Statutes Section 10a-6a. The report contains accountability measures developed through the Performance Measures Task Force and approved by the Board of Governors for Higher Education. The measures…

Connecticut Department of Higher Education (NJ1), 2009

2009-01-01

434

Higher Education Counts: Achieving Results. 2007 Report  

ERIC Educational Resources Information Center

"Higher Education Counts" is the annual accountability report on Connecticut's state system of higher education, as required under Connecticut General Statutes Section 10a-6a. The report contains accountability measures developed through the Performance Measures Task Force and approved by the Board of Governors for Higher Education. The measures…

Connecticut Department of Higher Education (NJ1), 2007

2007-01-01

435

Higher Education Counts: Achieving Results. 2008 Report  

ERIC Educational Resources Information Center

"Higher Education Counts" is the annual accountability report on Connecticut's state system of higher education, as required under Connecticut General Statutes Section 10a-6a. The report contains accountability measures developed through the Performance Measures Task Force and approved by the Board of Governors for Higher Education. The measures…

Connecticut Department of Higher Education (NJ1), 2008

2008-01-01

436

Higher Education Counts: Achieving Results. 2006 Report  

ERIC Educational Resources Information Center

"Higher Education Counts" is the annual accountability report on Connecticut's state system of higher education, as required under Connecticut General Statutes Section 10a-6a. The report contains accountability measures developed through the Performance Measures Task Force and approved by the Board of Governors for Higher Education. The measures…

Connecticut Department of Higher Education (NJ1), 2006

2006-01-01

437

Evaluation of plasma eosinophil count and mean platelet volume in patients with coronary slow flow  

PubMed Central

OBJECTIVE: The pathophysiology of coronary slow flow has not been clearly defined, although multiple abnormalities including arteritis, endothelial dysfunction, and atherothrombosis, have been reported. It is known that eosinophils play an important role in inflammation, endothelial dysfunction, and thrombosis. We aimed to compare the eosinophil counts of coronary slow flow patients versus healthy controls. METHODS: This study included 50 coronary slow flow patients (19 males, mean age 65.6±13.7 years) and 30 healthy controls (10 males, mean age 57.86±11.6 years). These participants were evaluated using concurrent routine biochemical tests as well as neutrophil, lymphocyte, and eosinophil counts and mean platelet volume (MPV), which were obtained from the whole blood count. These parameters were compared between groups. RESULTS: The baseline characteristics of the study groups were comparable. The coronary slow flow patients had a higher mean platelet volume and eosinophil count than the control group (8.38±0.86 vs 6.28±1.6 fL and 0.31±0.42 vs 0.09±0.05; p<0.001 and 0.008, respectively). CONCLUSION: Our study demonstrated a relationship between eosinophil count and MPV in patients with coronary slow flow. PMID:24838897

Demir, Mehmet; Cosar, Selvi; Melek, Mehmet

2014-01-01

438

Quantum abacus for counting and factorizing numbers  

SciTech Connect

We generalize the binary quantum counting algorithm of Lesovik, Suslov, and Blatter [Phys. Rev. A 82, 012316 (2010)] to higher counting bases. The algorithm makes use of qubits, qutrits, and qudits to count numbers in a base-2, base-3, or base-d representation. In operating the algorithm, the number ncounting task naturally leads to the shift operation and an algorithm based on the quantum Fourier transformation. We discuss possible implementations of the algorithm using quantum spin-d systems, d-well systems, and their emulation with spin-1/2 or double-well systems. We establish the analogy between our counting algorithm and the phase estimation algorithm and make use of the latter's performance analysis in stabilizing our scheme. Applications embrace a quantum metrological scheme to measure voltage (an analog to digital converter) and a simple procedure to entangle multiparticle states.

Suslov, M. V. [Moscow Institute of Physics and Technology, Institutskii per. 9, 141700 Dolgoprudny, Moscow District (Russian Federation); R and D Department, NIX Computer Company, Zvezdniy boulevard 19, 129085 Moscow (Russian Federation); Lesovik, G. B. [L. D. Landau Institute for Theoretical Physics, Russian Academy of Sciences, 117940 Moscow (Russian Federation); Blatter, G. [Theoretische Physik, ETH Zurich, Wolfgang-Pauli-Strasse 27, CH-8093 Zuerich (Switzerland)

2011-05-15

439

Modeling HIV-1 Dynamics and the Effects of Decreasing Activated Infected T-cell Count by Filtration  

E-print Network

in a dialysis process to filter HIV-1 from the blood5,6 . In these tests, affinity hemodialysis captured gp120Modeling HIV-1 Dynamics and the Effects of Decreasing Activated Infected T-cell Count by Filtration years mathematical models have been developed using differential equations for the progression of HIV-1

Stryker, Gabrielle A.

440

Phagocytic and bactericidal activities of leukocytes in whole blood from atomic bomb survivors  

SciTech Connect

This study evaluated the phagocytic and bactericidal activities of peripheral blood leukocytes from Hiroshima and Nagasaki atomic bomb survivors for Staphylococcus aureus. The data were analyzed by multiple linear regression for age, sex, radiation exposure, city of exposure, and neutrophil counts. No significant radiation effect was observed for either blood phagocytic or bactericidal activities. The only significant variable for these functions was the neutrophil count.

Sasagawa, S.; Yoshimoto, Y.; Toyota, E.; Neriishi, S.; Yamakido, M.; Matsuo, M.; Hosoda, Y.; Finch, S.C. (Hiroshima Univ. (Japan))

1990-10-01

441

What Counts as Knowing? The Development of Conceptual and Procedural Knowledge of Counting from Kindergarten through Grade 2  

ERIC Educational Resources Information Center

The development of conceptual and procedural knowledge about counting was explored for children in kindergarten, Grade 1, and Grade 2 (N = 255). Conceptual knowledge was assessed by asking children to make judgments about three types of counts modeled by an animated frog: standard (correct) left-to-right counts, incorrect counts, and unusual…

LeFevre, Jo-Anne; Smith-Chant, Brenda L.; Fast, Lisa; Skwarchuk, Sheri-Lynn; Sargla, Erin; Arnup, Jesse S.; Penner-Wilger, Marcie; Bisanz, Jeffrey; Kamawar, Deepthi

2006-01-01

442

Primary brain tumors treated with steroids and radiotherapy: Low CD4 counts and risk of infection  

SciTech Connect

Purpose: Patients with primary brain tumors are often treated with high doses of corticosteroids for prolonged periods to reduce intracranial swelling and alleviate symptoms such as headaches. This treatment may lead to immunosuppression, placing the patient at risk of life-threatening opportunistic infections, such as Pneumocystis carinii pneumonia. The risk of contracting some types of infection may be reduced with prophylactic antibiotics. The purpose of this study was to determine the occurrence of low CD4 counts and whether monitoring CD4 counts during and after radiotherapy (RT) is warranted. Methods and Materials: CD4 counts were measured during RT in 70 of 76 consecutive patients with newly diagnosed Grade III and IV astrocytoma and anaplastic oligodendroglioma treated with corticosteroids and seen at the Johns Hopkins Hospital. Weekly CD4 measurements were taken in the most recent 25 patients. Prophylactic trimethoprim-sulfamethoxazole (160 mg/800 mg p.o. every Monday, Wednesday, and Friday) or dapsone (100 mg p.o. daily) in those with sulfa allergy was prescribed only if patients developed a low CD4 count. Carmustine chemotherapy wafers were placed at surgery in 23% of patients, evenly distributed between the groups. No patient received any other chemotherapy concurrent with RT. Results: CD4 counts decreased to <200/mm{sup 3} in 17 (24%) of 70 patients. For the 25 patients with weekly CD4 counts, all CD4 counts were >450/mm{sup 3} before RT, but 6 (24%) of 25 fell to <200/mm{sup 3} during RT. Patients with counts <200/mm{sup 3} were significantly more likely to be hospitalized (41% vs. 9%, p <0.01) and be hospitalized for infection (23% vs. 4%, p <0.05) during RT. Overall survival was not significantly different between the groups. All patients with low CD4 counts were treated with prophylactic antibiotics, and no patient developed Pneumocystis carinii pneumonia. No patients developed a serious adverse reaction to antibiotic therapy. The mean dose of steroids, mean minimal white blood cell count, and number of patients treated with Gliadel wafers were not significantly different between the groups. Conclusion: The results of this study have confirmed the clinical impression that the use of high-dose corticosteroids and RT in patients with primary brain cancer is sufficient to result in severe immunosuppression and place these patients at risk of life-threatening opportunistic infections. A protocol of prophylactic antibiotics for those at risk may help prevent a potentially fatal side effect of treatment. A prospective study is underway to determine the frequency, depth, and prognostic implications of this finding.

Hughes, Michael A. [Department of Radiation Oncology and Molecular Radiation Sciences, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD (United States); Parisi, Michele [Department of Radiation Oncology and Molecular Radiation Sciences, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD (United States); Grossman, Stuart [Department of Radiation Oncology and Molecular Radiation Sciences, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD (United States); Kleinberg, Lawrence [Department of Radiation Oncology and Molecular Radiation Sciences, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD (United States)]. E-mail: kleinla@jhmi.edu

2005-08-01

443

Direct determination of external radiation dose in human blood  

E-print Network

In this study it was shown that it is possible to determine radiation doses from external beam therapy both directly and retrospectively from a human blood sample. To the best of our knowledge no other studies exist on the direct measurement of doses received by a person from external beam therapy. Optically stimulated luminescence counts from a healthy blood sample exposed to an external radiation source were measured. Blood aliquots were given 0, 1, 2, 3, 4, 5, 10, 15, 20, 25, 50, 100 and 200Gy beta doses and their decay and dose-response curves were plotted. While the luminescence intensities were found to be relatively low for the doses smaller than 10Gy, they were measured considerably higher for doses greater than 10Gy. The dose received by the blood aliquots was determined by interpolating the luminescence counts of 10Gy to the dose-response curve. This study has important ramifications for healthcare, medicine and radiation protection

Tanir, AG; Sahiner, E; Bolukdemir, MH; Koc, K; Meric, N; Keles, SK; Kucuk, O

2014-01-01

444

Clinically suspected acute myopericarditis with cardiac tamponade associated with peripheral blood eosinophilia presenting in early pregnancy: a case report  

PubMed Central

Introduction The clinical presentation of eosinophilic myocarditis may vary from asymptomatic to the manifestation of severe symptoms, including cardiac tamponade and arrhythmias. In pregnant patients with this condition, drugs must be used cautiously up to approximately the 4th month of pregnancy because drug use should be limited during the period of fetal organogenesis. Case presentation A 30-year-old Asian woman at 14 weeks of pregnancy with progressive malaise was hospitalized. The electrocardiogram revealed ST elevation and low QRS voltage. Echocardiography revealed massive pericardial effusion and myocardial swelling. A laboratory examination revealed an increase in her white blood cell count, with a predominance of neutrophils. Pericardial drainage was performed for relief of the cardiac tamponade. The pericardial effusion revealed an abundance of eosinophils. Subsequently, the peripheral blood eosinophil count began to rise, and the patient was clinically diagnosed with eosinophilic myopericarditis. The patient’s condition improved rapidly following the initiation of prednisolone treatment, and she finally delivered a full-term normal infant. Conclusions A patient with clinically suspected myopericarditis in the early stage of pregnancy who improved rapidly with pericardial drainage and prednisolone therapy, and successfully delivered a normal full-term infant; the diagnosis was made in the early stage of the disease, based on the detection of an abundance of eosinophils in the pericardial effusion preceding the subsequent development of peripheral blood eosinophilia. PMID:23668918

2013-01-01

445

Count rate limitations for pulse-counting instrumentation in pulsed accelerator fields.  

PubMed

This paper discusses various concepts involved in the counting losses of pulse-counting health physics instrumentation when used within the pulsed radiation environments of typical accelerator fields in order to preestablish appropriate limitations in use. Discussed are the "narrow" pulse and the "wide" pulse cases, the special effect of neutron moderating assemblies, and the effect of pulse fine microstructure on the counting losses of the pulse-counting instrumentation. In the narrow-pulse case, the accelerator pulse width is less than or equal to the instrument's dead time; whereas in the wide-pulse case, the accelerator pulse width is significantly longer than the instrument's dead time. Examples are provided that highlight the various concepts and limitations. PMID:22134075

Justus, Alan L

2012-01-01

446

CEA blood test  

MedlinePLUS

Carcinoembryonic antigen blood test ... A blood sample is needed. ... When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging sensation. Afterward, there may be some throbbing or a slight bruise. ...

447

Low Blood Pressure  

MedlinePLUS

Low blood pressure; Blood pressure - low; Postprandial hypotension; Orthostatic hypotension; Neurally mediated hypotension; NMH ... Blood pressure varies from one person to another. A drop as little as 20 mmHg, can cause ...

448

High Blood Pressure (Hypertension)  

MedlinePLUS

... Women and Diabetes Heart Health for Women High Blood Pressure (Hypertension) Print and Share (PDF 109 KB) ... very sick or even die. What does high blood pressure do to your body? High blood pressure ...

449

High blood pressure medications  

MedlinePLUS

... blood pressure medicine listed below comes in different brand and generic names. One or more of these ... blood vessels, which lowers your blood pressure. Angiotensin II receptor blockers (also called ARBs ) work in about ...

450

High Blood Pressure  

MedlinePLUS

... normal blood pressure 140/90 or higher is high blood pressure Between 120 and 139 for the top number, ... prehypertension. Prehypertension means you may end up with high blood pressure, unless you take steps to prevent it. High ...

451

Hypertension (High Blood Pressure)  

MedlinePLUS

... of pregnant women get this condition. How Does High Blood Pressure Affect the Body? High blood pressure adds to ... treated immediately. Back Continue How Do Doctors Diagnose High Blood Pressure? For most teens, the only way to know ...

452

Coughing up blood  

MedlinePLUS

... gastrointestinal tract. Blood that comes up with a cough often looks bubbly because it is mixed with ... conditions, diseases, and medical tests may make you cough up blood. These include: Blood clot in the ...

453

Red blood cell production  

MedlinePLUS Videos and Cool Tools

... or another. Red blood cells are an important element of blood. Their job is to transport oxygen ... hemocytoblasts give rise to all of the formed elements in blood. If a hemocytoblast commits to becoming ...

454

Modeling zero-inflated count data when exposure varies: With an application to tumor counts.  

PubMed

This paper is concerned with the analysis of zero-inflated count data when time of exposure varies. It proposes a modified zero-inflated count data model where the probability of an extra zero is derived from an underlying duration model with Weibull hazard rate. The new model is compared to the standard Poisson model with logit zero inflation in an application to the effect of treatment with thiotepa on the number of new bladder tumors. PMID:24003010

Baetschmann, Gregori; Winkelmann, Rainer

2013-09-01

455

Changes in platelet count and related parameters in SART-stressed mice and the action of administered neurotropin.  

PubMed

In order to hematologically characterize SART-stressed (repeated cold-stressed) animals, which are regarded as model animals of clinical dysautonomia, general hematological analyses were performed in mice subjected to various types of stress. SART-stressed mice showed significant increases in erythrocyte count, hemoglobin, hematocrit and specific gravity of whole blood, no change in leukocyte count and a marked decrease in platelet count. Among the above changes, the decreased platelet count was particularly characteristic of SART-stressed mice. Splenectomy failed to inhibit the SART stress-induced thrombocytopenia. Bone marrow megakaryocyte counts increased following the stress. The bleeding time of SART-stressed mice was more than double that of normal mice. Consecutive administrations of Neurotropin, a sedative analgesic, completely blocked the alterations in platelet count, megakaryocyte count and bleeding time in SART-stressed mice without producing any effect in unstressed mice. From the present results, it is suggested that SART-stressed mice may be characterized by thrombocytopenia, which is not attributable to enhanced function of the spleen or suppressed platelet production in the bone marrow. Moreover, Neurotropin appears to be effective for moderating SART stress. PMID:3184566

Hata, T; Kawabata, A; Kita, T; Itoh, E; Nishimura, Y

1988-08-01

456

Automated imaging, identification, and counting of similar cells from digital hologram reconstructions  

NASA Astrophysics Data System (ADS)

This paper presents our method, which simultaneously combines automatic imaging, identification, and counting with the acquisition of morphological information for at least 1000 blood cells from several three-dimensional images of the same sample. We started with seeking parameters to differentiate between red blood cells that are similar but different with respect to their development stage, i.e., mature or immature. We highlight that these cells have different diffractive patterns with complementary central intensity distribution in a given plane along the propagation axis. We use the Fresnel approximation to simulate propagation through cells modeled as spheroid-shaped phase objects and to find the cell property that has the dominant influence on this behavior. Starting with images obtained in the reconstruction step of the digital holographic microscopy technique, we developed a code for automated simultaneous individual cell image separation, identification, and counting, even when the cells are partially overlapped on a slide, and accurate measuring of their morphological features. To find the centroids of each cell, we propose a method based on analytical functions applied at threshold intervals. Our procedure separates the mature from the immature red blood cells and from the white blood cells through a decision based on gradient and radius values.

Mihailescu, Mona; Scarlat, Mihaela; Gheorghiu, Alexandru; Costescu, Julia; Kusko, Mihai; Paun, Irina Alexandra; Scarlat, Eugen

2011-07-01

457

Automated imaging, identification, and counting of similar cells from digital hologram reconstructions.  

PubMed

This paper presents our method, which simultaneously combines automatic imaging, identification, and counting with the acquisition of morphological information for at least 1000 blood cells from several three-dimensional images of the same sample. We started with seeking parameters to differentiate between red blood cells that are similar but different with respect to their development stage, i.e., mature or immature. We highlight that these cells have different diffractive patterns with complementary central intensity distribution in a given plane along the propagation axis. We use the Fresnel approximation to simulate propagation through cells modeled as spheroid-shaped phase objects and to find the cell property that has the dominant influence on this behavior. Starting with images obtained in the reconstruction step of the digital holographic microscopy technique, we developed a code for automated simultaneous individual cell image separation, identification, and counting, even when the cells are partially overlapped on a slide, and accurate measuring of their morphological features. To find the centroids of each cell, we propose a method based on analytical functions applied at threshold intervals. Our procedure separates the mature from the immature red blood cells and from the white blood cells through a decision based on gradient and radius values. PMID:21743570

Mihailescu, Mona; Scarlat, Mihaela; Gheorghiu, Alexandru; Costescu, Julia; Kusko, Mihai; Paun, Irina Alexandra; Scarlat, Eugen

2011-07-10

458

Low level counting from meteorites to neutrinos  

SciTech Connect

The development in low level counting at Heidelberg with NaI(Tl) crystals, proportional counters and Germanium detectors is reviewed throughout the course of almost 40 years of experience. Research subjects changed from cosmogenic radionuclides in meteorites to solar neutrinos and double beta decay. Driven by screening measurements for these rare event experiments, the sensitivity in single gamma counting has gained almost 3 orders of magnitude. With Ge spectrometry the {mu}Bq/kg range is now accessible. It is discussed how further improvements can be realized. There is potential to reach a sensitivity at the level of 10 to 100 nBq/kg for cryogenic liquid type Gespectroscopy, a technique which the next generation 76Ge double beta decay experiment GERDA is based on.

Heusser, Gerd [Max-Planck-Institute for Nuclear Physics, POB 103980, D-69029 Heidelberg (Germany)

2005-09-08

459

How fast can quantum annealers count?  

NASA Astrophysics Data System (ADS)

We outline an algorithm for the quantum counting problem using adiabatic quantum computation (AQC). We show that the mechanism of quantum-adiabatic evolution may be utilized toward estimating the number of solutions to a problem, and not only to find them. Using local adiabatic evolution, a process in which the adiabatic procedure is performed at a variable rate, the problem of counting the number of marked items in an unstructured database is solved quadratically faster than the corresponding classical algorithm. The above algorithm provides further evidence for the potentially powerful capabilities of AQC as a paradigm for more efficient problem solving on a quantum computer, and may be used as the basis for solving more sophisticated problems.

Hen, Itay

2014-06-01

460

Count-a-thon of airplane contrails  

Microsoft Academic Search

The third Contrail Count-a-Thon of the GLOBE (Global Learning and Observations to Benefit the Environment) project is being held during Earth Science Week 2005 in October. Reports of sky observations---including those of contrail-free skies---taken between 11:00 A.M. and 1:00 P.M. local time on 13 October 2005 are welcome from any interested observers (including Eos readers), whether or not they are

L. H. Chambers; D. P. Duda

2005-01-01

461

Inventory verification measurements using neutron multiplicity counting  

SciTech Connect

This paper describes a series of neutron multiplicity measurements of large plutonium samples at the Los Alamos Plutonium Facility. The measurements were corrected for bias caused by neutron energy spectrum shifts and nonuniform multiplication, and are compared with calorimetry/isotopics. The results show that multiplicity counting can increase measurement throughput and yield good verification results for some inventory categories. The authors provide recommendations on the future application of the technique to inventory verification.

Ensslin, N.; Foster, L.A.; Harker, W.C.; Krick, M.S.; Langner, D.G.

1998-12-31

462

Two applications of complementation via inductive counting  

Microsoft Academic Search

A recent proof that nondeterministic space-bounded complexity classes are closed under complementation is used to develop two further applications of the inductive counting technique. An errorless probabilistic algorithm is given for the undirected graph s-t connectivity problem that runs in O(log n) space and polynomial expected time, and it is shown that the class LOGCFL is closed under complementation. The

Allan Borodin; Stephen A. Cook; P. W. Dymond; Walter L. Ruzzo; Martin Tompa

1988-01-01

463

Some counting problems related to permutation groups  

E-print Network

of the problem of counting the orbits of an infinite per­ mutation group on n­sets or n­tuples, especially­uniform) hypergraph we would need a k­ary relation for each cardinality k of hyperedges. The age of M , written Age terminology was invented by Fra¨iss'e [7], who says that the structure M is younger than N if the age of M

Cameron, Peter

464

Counting powers of words in monoids  

Microsoft Academic Search

For a monoid M with presentation M=?a1,…,ar|w1=w2,…,w2s?1=w2s?, we count the number of words equivalent to w1n,n?N, where equivalent means under the transitive closure of the relation generated by replacing an occurrence of w2i?1 by w2i or vice versa (for any i). Many interesting sequences are obtained in this way including the Fibonacci numbers.

Stephen P. Humphries; Zane Kun Li

2009-01-01

465

Count Your Lucky Stars: Sampling in Astronomy  

NSDL National Science Digital Library

This is an activity about sampling specifically in astronomy. Learners will make a sampling window in order to estimate the number of stars in the sky visible to the unaided eye. After, they will discuss how to estimate the effect of different variables on their counts, such as sky brightness, dark adaptation, cloud cover, etc. Please note use of a clear night sky is optimal for this activity.

466

Positive motivic measures are counting measures  

Microsoft Academic Search

Let K be a field. A positive motivic measure on the Grothendieck ring K_0(Var_K) is a homomorphism from K_0(Var_K) to the real numbers assigning a nonnegative value to every variety. In this note we show that the only positive motivic measures are the counting measures: measures on K_0(Var_{F_q}) which send a variety to its number of rational points over some

Jordan S. Ellenberg; Michael Larsen

2009-01-01

467

Photon counting ladar work at FOI, Sweden  

NASA Astrophysics Data System (ADS)

Photon counting techniques using direct detection has recently gained considerable interest within the laser radar community. The high sensitivity is of special importance to achieve high area coverage in surveillance and mapping applications and long range with compact systems for imaging, profiling and ranging. New short pulse lasers including the super continuum laser is of interest for active spectral imaging. A special technique in photon counting is the "time correlated single photon counting" (TCSPC). This can be utilized together with short pulse (ps) lasers to achieve very high range resolution and accuracy (mm level). Low average power lasers in the mW range enables covert operation with respect to present laser warning technology. By analyzing the return waveform range and shape information from the target can be extracted. By scanning the beam high resolution 3D images are obtained. At FOI we have studied the TCSPC with respect to range profiling and imaging. Limitations due to low SNR and dwell times are studied in conjunction with varying daylight background and atmospheric turbulence. Examples of measurements will be presented and discussed with respect to some system applications.

Steinvall, Ove; Sjöqvist, Lars; Henriksson, Markus

2012-06-01

468

Curves, dynamical systems, and weighted point counting.  

PubMed

Suppose X is a (smooth projective irreducible algebraic) curve over a finite field k. Counting the number of points on X over all finite field extensions of k will not determine the curve uniquely. Actually, a famous theorem of Tate implies that two such curves over k have the same zeta function (i.e., the same number of points over all extensions of k) if and only if their corresponding Jacobians are isogenous. We remedy this situation by showing that if, instead of just the zeta function, all Dirichlet L-series of the two curves are equal via an isomorphism of their Dirichlet character groups, then the curves are isomorphic up to "Frobenius twists", i.e., up to automorphisms of the ground field. Because L-series count points on a curve in a "weighted" way, we see that weighted point counting determines a curve. In a sense, the result solves the analogue of the isospectrality problem for curves over finite fields (also know as the "arithmetic equivalence problem"): It states that a curve is determined by "spectral" data, namely, eigenvalues of the Frobenius operator of k acting on the cohomology groups of all ?-adic sheaves corresponding to Dirichlet characters. The method of proof is to show that this is equivalent to the respective class field theories of the curves being isomorphic as dynamical systems, in a sense that we make precise. PMID:23716684

Cornelissen, Gunther

2013-06-11

469

Inhibition of red blood cell-induced platelet aggregation in whole blood by a nonionic surfactant, poloxamer 188 (Rheothrx ® Injection)  

Microsoft Academic Search

RheothRx Injection, an aqueous solution of a nonionic block copolymer (poloxamer 188) formulated for intravenous administration, was investigated as an inhibitor of red blood cell (RBC)-induced platelet aggregation at plasma concentrations of 0.05-5mgmL?1. Platelet aggregation was determined by measuring the fall in single platelet counts after mechanical agitation of 2mL aliquots of citrated whole blood in a 37°C shaking waterbath.

Jonathan K. Armstrong; Herbert J. Meiselman; Timothy C. Fisher

1995-01-01

470

Alternatives to blood transfusion.  

PubMed

The use of alternatives to allogeneic blood continues to rest on the principles that blood transfusions have inherent risks, associated costs, and affect the blood inventory available for health-care delivery. Increasing evidence exists of a fall in the use of blood because of associated costs and adverse outcomes, and suggests that the challenge for the use of alternatives to blood components will similarly be driven by costs and patient outcomes. Additionally, the risk-benefit profiles of alternatives to blood transfusion such as autologous blood procurement, erythropoiesis-stimulating agents, and haemostatic agents are under investigation. Nevertheless, the inherent risks of blood, along with the continued rise in blood costs are likely to favour the continued development and use of alternatives to blood transfusion. We summarise the current roles of alternatives to blood in the management of medical and surgical anaemias. PMID:23706802

Spahn, Donat R; Goodnough, Lawrence T

2013-05-25

471

Coincidence detection of heterogeneous cell populations from whole blood with coplanar electrodes in a microfluidic impedance cytometer.  

PubMed

Particle counting finds many industrial applications especially in medical healthcare. In particular, cell counting from whole blood is used pervasively for disease diagnostics. Microfluidic impedance cytometry is fast, requires a small volume of blood, can be used at point of care and can perform absolute enumeration of different cell types in the sample. Coincidence detection is very essential for accurate counting results and becomes more significant while counting specific target cells, e.g. CD4(+) or CD8(+) T cell count in HIV/AIDS patient blood samples. In heterogeneous samples, e.g. blood, cell differentiation for all coincidence occurrences is essential in addition to the coincidence detection for accurate cell enumeration. In this paper, we have characterized the coincidence detection with cell differentiation using a microfluidic impedance biochip. The pure population of leukocytes is obtained after all erythrocytes are lysed on-chip from whole blood. Leukocytes were counted electrically as they pass over coplanar microfabricated electrodes bonded to the 15 ?m × 15 ?m cross section counting channel while generating a bipolar pulse for each cell passage. We have developed a mathematical model to simulate the electrical cell pulse and its coincidences. We show that coincidence detection can be characterized into three main types based on the range of time delay at which the coincidence occurs. We have also characterized cell differentiation for all the three coincidence types and show that multiple coincidences of different types can also occur. We used healthy and HIV-infected patient blood samples and used our coincidence detection technique to count CD4(+) and CD8(+) T cells and show the improvement in accuracy of cell counts compared to that without coincidence detection. We have also shown the improvement in the erythrocyte counting with coincidence detection in diluted whole blood samples. PMID:25231594

Hassan, U; Bashir, R

2014-10-14

472

Evaluation of an easy and affordable flow cytometer for volumetric haematopoietic stem cell counting  

PubMed Central

Background Accurate estimation of haematopoietic stem cell (HSC) counts by flow cytometry may be difficult in laboratories in which sophisticated equipment and staff with specific expertise are not available. Affordable flow cytometers that can perform basic functions may help to overcome these difficulties. In this study we compared HSC and leucocyte counts determined by volumetric and bead-based protocols performed with the small, low-cost Accuri® C6, with those obtained with two gold-standard instruments, the four-colour FACSCalibur® and the eight-colour FACSCantoII®, our reference flow cytometers. Materials and methods With the three cytometers we tested, in parallel, 111 consecutive samples from cord blood, peripheral blood from patients with myelofibrosis and myeloproliferative syndromes, fresh and thawed HSC collected by apheresis and bone marrow products. The findings were compared with one-way ANOVA, Bland-Altman analysis and linear regression. Results The results of HSC and leucocyte enumeration by the three devices were strongly correlated (r2>0.99; p<0.0001). ANOVA performed on different subgroups of samples did not reveal significant differences between HSC count determined by the C6 bead-based and reference flow cytometers in any of the subgroups. Regarding the C6 volumetric protocol, a statistically significant difference was observed only in the cord blood subgroup. Time for instrument set-up, calibration and analysis was slightly longer with Accuri® C6 (40 min) than with FACSCantoII® (30 min). Discussion Accuri® C6 is a reliable instrument for HSC enumeration in fresh samples, using both volumetric and bead-based approaches, although the volumetric protocol on cord blood samples needs to be improved. The Accuri® C6 is easy to use, does not require profound knowledge of flow cytometry and could be employed in an urgent setting. Its performance may be improved by more efficient calibration and shorter analysis time. PMID:24887218

Mariani, Mariagabriella; Colombo, Federico; Assennato, Sonny M.; Frugoni, Cecilia; Cattaneo, Alessandra; Trombetta, Elena; Rebulla, Paolo; Porretti, Laura

2014-01-01

473

Original article Reconstitution of mastitic milk by adding blood  

E-print Network

Original article Reconstitution of mastitic milk by adding blood plasma and leukocytes into low cell count milk W Fang M Vikerpuur, M Sandholm Department of Pharmacology and Toxicology, Faculty 1995; accepted 29 August 1995) Summary ― Milk from inflamed quarters is high in somatic cells

Paris-Sud XI, Université de

474

Blood contamination of used dental anesthetic cartridges.  

PubMed

This study sought to determine the levels of blood contamination found in and/or on used dental anesthetic cartridges and to measure antibacterial effects after exposure to a local anesthetic solution. The study analyzed a total of 1000 used cartridges from an oral surgery clinic, containing 1 of 3 anesthetic types. Blood testing included visual observations (using a dissecting microscope) and chemical analyses. From each cartridge, either 0.5 ml of residual anesthetic solution or a combination of anesthetic solution plus added saline was removed. Using reagent strip dipsticks, the solutions were analyzed for minute amounts of blood. Visual examinations were scored on a positive or negative scale. In addition, 4 types of bacteria were mixed with lidocaine or phosphate buffered saline (PBS) for up to 30 days, and viable cell counts decreases were measured for the 2 solutions. A majority of the cartridges evaluated contained lidocaine, and while only 7 of the 1000 cartridges examined contained visible blood, the reagent strips detected blood in more than 76% of all cartridges. Lidocaine and PBS produced similar bacterial death rates. The authors concluded that blood contamination levels in the absence of pronounced antibacterial activity indicate that dental anesthetic cartridges could be considered a potential type of regulated medical waste. PMID:23454319

Romito, L; Svetanoff, E; Palenik, C J

2013-01-01

475

BUN - blood test  

MedlinePLUS

Blood urea nitrogen ... A blood sample is needed. Most of the time blood is typically drawn from a vein located on the ... Many medicines can interfere with blood test results. Your health ... if you need to stop taking any medicines before you have this ...

476

Endothelial cell Blood cells  

E-print Network

Endothelial cell HSCs Blood cells Blood vessel Haemogenic endothelial cell Figure 1 | Relationship between endothelial cells and blood cells. Endothelial cells line the inside of blood vessels. During mouse embryonic development, a subset of these cells, known as haemogenic endothelial cells, seems

Wilmers, Chris

477

Blood Bank Inventory Control  

Microsoft Academic Search

Essentially, blood banks are facilities which procure, store, process, and dispense blood. To operate effectively in the face of both random supply and random demand, sizable buffer stocks of blood are maintained. The resulting inventory control problem is an extremely complex one for several reasons: (1) both supply and demand are random; (2) approximately 50 percent of all bloods demanded,

John B. Jennings

1973-01-01

478

Spurious platelet counts in acute leukaemia with DIC due to cell fragmentation.  

PubMed

Automated platelet counts in a patient with newly diagnosed AML M5 with extreme leukocytosis were reported as 129, 166 and 121 x 10(9)/1. Routine blood films showed a corresponding number of platelet-sized particles, judged to be platelets. The patient was treated for DIC with low-dose heparin infusion. Platelet transfusions were not given initially. The patient died 14 h after admission from intracerebral haematoma. The origin of the platelet-sized particles seen in routine stained blood films was examined by cytochemical and immunological staining for peroxidase, non-specific esterase, CD 13 and CD 33. About 1/3 of the fragments had the same staining characteristics as the leukaemia cells, indicating leukaemia cell origin. Staining for platelet-specific antigen GpIIIa was positive only in 4% of the platelet-sized fragments, with a calculated true platelet count of 4 x 10(9)/1. The presence of cell fragments masquerading as platelets should be suspected in leukaemia patients with bleeding symptoms and normal or near normal platelet counts. PMID:1451403

Hammerstrøm, J

1992-01-01

479

Size referenced electronic leukocyte counting threshold and lysed leukocyte size distribution of common domestic animal species.  

PubMed

Using a single channel electronic cell counter and attached particle size analyzer, leukocyte size distribution histograms were determined on canine, feline, bovine, and equine blood diluted with chloride-based diluent and treated with a conventional stromatolysin. Histograms were usually unimodal, but a few were bimodal. Mean values for mean lysed leukocyte particle volume were 49.2, 51.1, 55.4, and 65.0 fl for canine, feline, equine, and bovine blood, respectively. From inspection of histograms, a lower threshold of 30 fl referenced to latex spheres was interpreted to be appropriate for counting leukocytes of these four species simultaneously. Debris below the threshold was seen in many samples and was usually separated from the leukocyte population by a valley touching the histogram baseline at the threshold channel. Debris resulted in a visually detectable threshold failure by extending considerably into the leukocyte size range in 9% of feline, 9% of canine, and 7% of bovine samples. It is recommended that careful establishment of the lower counting threshold will minimize frequency and severity of leukocyte count error associated with failure to exclude debris. PMID:3455085

Weiser, M G

1987-11-01

480

A mind you can count on: validating breath counting as a behavioral measure of mindfulness  

PubMed Central

Mindfulness practice of present moment awareness promises many benefits, but has eluded rigorous behavioral measurement. To date, research has relied on self-reported mindfulness or heterogeneous mindfulness trainings to infer skillful mindfulness practice and its effects. In four independent studies with over 400 total participants, we present the first construct validation of a behavioral measure of mindfulness, breath counting. We found it was reliable, correlated with self-reported mindfulness, differentiated long-term meditators from age-matched controls, and was distinct from sustained attention and working memory measures. In addition, we employed breath counting to test the nomological network of mindfulness. As theorized, we found skill in breath counting associated with more meta-awareness, less mind wandering, better mood, and greater non-attachment (i.e., less attentional capture by distractors formerly paired with reward). We also found in a randomized online training study that 4 weeks of breath counting training improved mindfulness and decreased mind wandering relative to working memory training and no training controls. Together, these findings provide the first evidence for breath counting as a behavioral measure of mindfulness. PMID:25386148

Levinson, Daniel B.; Stoll, Eli L.; Kindy, Sonam D.; Merry, Hillary L.; Davidson, Richard J.

2014-01-01

481

Electrical cell counting process characterization in a microfluidic impedance cytometer  

E-print Network

measurement channel used to electrically count the cells. We show that cell counting over time is a non-homogeneous in milk (Phipps and Newbould 1996). Other examples include, particle size determination in composition

Bashir, Rashid

482

Differential leucocyte cell counts from the pygoscelid penguins of Antarctica.  

PubMed

Differential leucocyte counts were obtained for three cogeneric species of wild antarctic penguins, Pygoscelis adelie (adelie), Pygoscelis papua (gentoo), and Pygoscelis antarctica (chinstrap). Significant differences between the differential leucocyte counts of the three species were not observed. PMID:3625920

Zinsmeister, V A; VanDerHeyden, M J

1987-07-01

483

Enumeration of islets by nuclei counting and light microscopic analysis  

E-print Network

Islet enumeration in impure preparations by conventional dithizone staining and visual counting is inaccurate and operator dependent. We examined nuclei counting for measuring the total number of cells in islet preparations, ...

Pisania, Anna

484

25 CFR 81.21 - Counting of ballots.  

...21 Counting of ballots. All duly cast ballots are to be counted. Even though...whether the required percentage of voters have cast their ballots in the election. Invalid...determining the required percentage of votes...

2014-04-01

485

77 FR 65091 - National Character Counts Week, 2012  

Federal Register 2010, 2011, 2012, 2013

...Proclamation 8891--National Character Counts Week, 2012 Proclamation 8892--National Forest Products Week, 2012 Presidential Documents Federal Register...October 19, 2012 National Character Counts Week, 2012 By the President of the United...

2012-10-24

486

Blood transfusion in sports.  

PubMed

Blood transfusion is an effective and unmediated means of increasing the number of red blood cells in the circulation in order to enhance athletic performance. Blood transfusion became popular in the 1970s among elite endurance athletes and declined at the end of the 1980s with the introduction of recombinant erythropoietin. The successive implementation in 2001 of a direct test to detect exogenous erythropoietin and in 2004 of a test to detect allogeneic blood transfusion forced cheating athletes to reinfuse fully immunologically compatible blood. The implementation of indirect markers of blood doping stored in an Athlete's Biological Passport provides a powerful means to deter any form of blood transfusion. PMID:20020370

Giraud, Sylvain; Sottas, Pierre-Edouard; Robinson, Neil; Saugy, Martial

2010-01-01

487

Estimation and specification tests of count data recreation demand functions  

E-print Network

addressed this issue by employing various estimators which are based on a count distribution. Although researchers have recognized the need to model recreation demand as stemming from a count data generating process, there is little guidance in selecting... a stochastic model for this type of data, Previous research in this area has so far engaged only in heuristic comparisons of various count data estimators. Hence, as in standard regression analysis, it is desirable to test whether the fitted count...

Gomez, Irma Adriana

2012-06-07

488

A panoramic photon-counting detector system  

NASA Astrophysics Data System (ADS)

The characteristics and implementation of the Laval Image Photon-Counting System (LIPS) are described. LIPS is a flexible, compact, and transportable two-dimensional detector system which is currently in use in the spectroscopic mode on the 1.6 m telescope at the Mont Megantic Observatory. The detector is described, including the quantum efficiency, resolution, linearity, noise characteristics, and distortions. The data acquisition and display module is considered, including the computer, image display unit, Direct Memory Access Board which controls the detector, and control and data-acquisition program. Spectroscopy using LIPS is briefly addressed. The present assessment of the system and its future use are discussed.

Durand, Daniel; Hardy, Eduardo; Couture, Jean

1987-07-01

489

3.MD The Square Counting Shortcut  

NSDL National Science Digital Library

This is a task from the Illustrative Mathematics website that is one part of a complete illustration of the standard to which it is aligned. Each task has at least one solution and some commentary that addresses important asects of the task and its potential use. Here are the first few lines of the commentary for this task: Imagine that each square in the picture measures one centimeter on each side. What is the area of each letter? Try to work it out without counting each...

490

Numbers Count Workshop at Agnes Scott College  

NSDL National Science Digital Library

These workshop resources were provided for faculty interested in addressing the gap between mathematics and its application in biological problem solving. To support the observation, experimentation and modeling of data, the Numbers Count workshop will provide an introduction to data, tools, and curricular materials for use with undergraduates. We also addressed the lack of context that impedes student learningâÂÂstudents rightfully ask themselves why should they need to integrate arcsin x if they want to become a physician? This event was held at Agnes Scott College in Atlanta in January 2009.

Claudia Neuhauser (University of Minnesota Rochester;Health Sciences)

2009-01-09

491

1.NBT Start/Stop Counting II  

NSDL National Science Digital Library

This is a task from the Illustrative Mathematics website that is one part of a complete illustration of the standard to which it is aligned. Each task has at least one solution and some commentary that addresses important asects of the task and its potential use. Here are the first few lines of the commentary for this task: Setup Students should be seated on chairs at their tables or desks. The teacher will give a counting sequence (for example, 20-120) to the students. Ac...

492

Ortec: AN34 Experiment 2 - Geiger Counting  

NSDL National Science Digital Library

The purpose of this experiment is to familiarize the student with the Geiger-Mueller counter. Th