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1

Topical tar: Back to the future  

SciTech Connect

The use of medicinal tar for dermatologic disorders dates back to the ancient times. Although coal tar is utilized more frequently in modern dermatology, wood tars have also been widely employed. Tar is used mainly in the treatment of chronic stable plaque psoriasis, scalp psoriasis, atopic dermatitis, and seborrheic dermatitis, either alone or in combination therapy with other medications, phototherapy, or both. Many modifications have been made to tar preparations to increase their acceptability, as some dislike its odor, messy application, and staining of clothing. One should consider a tried and true treatment with tar that has led to clearing of lesions and prolonged remission times. Occupational studies have demonstrated the carcinogenicity of tar; however, epidemiologic studies do not confirm similar outcomes when used topically. This article will review the pharmacology, formulations, efficacy, and adverse effects of crude coal tar and other tars in the treatment of selected dermatologic conditions.

Paghdal, K.V.; Schwartz, R.A. [University of Medicine & Dentistry of New Jersey, Newark, NJ (United States)

2009-08-15

2

Topical Treatment in Acne: Current Status and Future Aspects  

Microsoft Academic Search

During the last 20 years, the number of topical and systemic drugs for the treatment of acne vulgaris has been enriched. Topical drugs on the one hand have been newly discovered or further developments of already available agents such as in the group of retinoids or galenic formulation have improved efficacy or local tolerance. Topical retinoids are a mainstay in

Harald P. M. Gollnick; Andrea Krautheim

2003-01-01

3

Selecting Research Topics: Personal Experiences and Speculations For the Future  

Microsoft Academic Search

In the rapidly changing field of information systems, every researcher faces important choices about what research topics to explore and how to pursue that research. This paper addresses these questions by summarizing a panel discussion at the 2001 Decision Sciences Institute (DSI) annual meeting. The first part of this paper provides a framework explaining factors that can be used in

Steven Alter; Alan R. Dennis

2002-01-01

4

Interaction and user experiences with multimedia technologies: challenges and future topics  

Microsoft Academic Search

In this paper, we investigate future topics and challenges of interaction and user experience in multimedia We bring together different perspectives from overlapping fields of research such as multimedia, human-computer interaction, information retrieval, networked multimedia, and creative arts. Based on potential intersections, we define three application domains to be investigated further, as they create high demand and good prospect for

Ansgar Scherp; Frank Nack; Klara Nahrstedt; Masashi Inoue; Andreas Girgensohn; Andreas Henrich; Philipp Sandhaus; Sabine Thieme; Michelle Zhou

2008-01-01

5

Topics  

ERIC Educational Resources Information Center

|Includes short discussion of perimeters of regular polygons having fixed areas, Fibonacci numbers, triangle transformations, transformational matrices, round-off errors, and a mathematical model for musical keys. (RS)|

Mathematics Teaching, 1970

1970-01-01

6

Specific Projects Which Can Be Included within the Framework of a Future Technical Assistance Program.  

National Technical Information Service (NTIS)

Conclusions from the joint analysis carried out by the Peru--USA Cooperative Group, include future cooperation in the following fields: energy resources and technology; analysis of the energy sector; and energy information system and environment. It is em...

1978-01-01

7

Estimates of New Mexico's Future Oil Production Including Reserves of the 50 Largest Pools.  

National Technical Information Service (NTIS)

This report consists of two parts: (1) an estimate of future oil production for New Mexico, including estimates for the northwest and southeast areas, and (2) an analysis of reserves of the 50 largest oil pools are included in the appendix. Production est...

R. W. Foster A. L. Gutjahr G. H. Warner

1978-01-01

8

Theory including future not excluded: Formulation of complex action theory II  

NASA Astrophysics Data System (ADS)

We study a complex action theory (CAT) whose path runs over not only past but also future. We show that, if we regard a matrix element defined in terms of the future state at time TB and the past state at time TA as an expectation value in the CAT, then we are allowed to have the Heisenberg equation, Ehrenfest's theorem, and the conserved probability current density. In addition, we show that the expectation value at the present time t of a future-included theory for large TB - t and large t - TA corresponds to that of a future-not-included theory with a proper inner product for large t - TA. Hence, the CAT with future explicitly present in the formalism and influencing in principle the past is not excluded phenomenologically, because the effects are argued to be very small in the present era. Furthermore, we explicitly derive the Hamiltonian for the future state via a path integral, and confirm that it is given by the Hermitian conjugate of the Hamiltonian for the past state.

Nagao, Keiichi; Nielsen, Holger Bech

2013-02-01

9

REVIEWS OF TOPICAL PROBLEMS: Astrophysical aspects of cosmic-ray research (first 75 years and outlook for the future)  

NASA Astrophysics Data System (ADS)

(Invited talk at the 20th International Cosmic Ray Conference, Moscow, 2-15 August 1987) The basic topics discussed here are the primary cosmic rays near the earth, cosmic rays in the universe, the origin of cosmic rays, a galactic model with a halo, and some prospects for future research.

Ginzburg, Vitalii L.

1988-06-01

10

43 CFR 3509.17 - What information must I include in my application for a future interest lease?  

Code of Federal Regulations, 2012 CFR

...MANAGEMENT, DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) LEASING OF SOLID MINERALS OTHER THAN COAL AND OIL SHALE Fractional and Future Interest Lease Applications § 3509.17 What information must I include in my application for a future...

2012-10-01

11

Estimates of future flow, including extremes, of the Columbia River headwaters  

NASA Astrophysics Data System (ADS)

Streamflow projections, including extremes, for the 2050s for the Columbia River headwaters above Donald are obtained by downscaling four regional climate models of the North American Regional Climate Change Assessment Program (NARCCAP) suite and subsequent driving of a hydrologic model. We employ the entire model chain from global and regional climate models, station-based statistical downscaling, and a fully distributed, physically based hydrologic model and verify the results against observed streamflow. The performance is model dependent but is generally encouraging enough to justify the application of the climate scenarios. A general warming of about 2°C is projected and, on average, slightly drier conditions, especially in late summer. We find evidence that the projected changes are elevation dependent and relatively small scale, with decreasing signals with higher elevations. All models project a shift of the hydrograph toward a more rain-fed regime, with peak flows occurring in June instead of July. Annual peak flow is projected to not increase, and August low flow decreases in all four models. With nonshrinking (static) glaciers, relatively high melting rates are simulated for August and September that partly compensate for the shifted hydrograph; this enhanced glacier melt is also detected in simulated historic Columbia headwater flow. The static approximation is supported by a heuristic seasonal sensitivity analysis that suggests a moderate average areal glacier recession of about 10% for the midcentury. We discuss the need for a dynamic glacier component for a refined assessment of future drought risk.

Bürger, G.; Schulla, J.; Werner, A. T.

2011-10-01

12

Key Factors in Planning a Sustainable Energy Future Including Hydrogen and Fuel Cells  

ERIC Educational Resources Information Center

|In this article, a number of future energy visions, especially those basing the energy systems on hydrogen, are discussed. Some often missing comparisons between alternatives, from a sustainability perspective, are identified and then performed for energy storage, energy transportation, and energy use in vehicles. It is shown that it is important…

Hedstrom, Lars; Saxe, Maria; Folkesson, Anders; Wallmark, Cecilia; Haraldsson, Kristina; Bryngelsson, Marten; Alvfors, Per

2006-01-01

13

Key Factors in Planning a Sustainable Energy Future Including Hydrogen and Fuel Cells  

ERIC Educational Resources Information Center

In this article, a number of future energy visions, especially those basing the energy systems on hydrogen, are discussed. Some often missing comparisons between alternatives, from a sustainability perspective, are identified and then performed for energy storage, energy transportation, and energy use in vehicles. It is shown that it is important…

Hedstrom, Lars; Saxe, Maria; Folkesson, Anders; Wallmark, Cecilia; Haraldsson, Kristina; Bryngelsson, Marten; Alvfors, Per

2006-01-01

14

Including Impacts of Climate Change in Long-Range Forecasts of Future Tuolumne River Streamflow  

NASA Astrophysics Data System (ADS)

Future streamflow is assessed for the Tuolumne River, a representative watershed in Sierra Nevada Mountains in California that provides 85% of the San Francisco Public Utility Commission's water supply for 2.5 million Bay Area residents and water to 8000 agricultural customers and over 200,000 electrical customers of the Turlock and Modesto Irrigation Districts. The Hydrocomp Forecasting and Analysis Model (HFAM) is a hydrologic simulation model which provides probabilistic inflow forecasts based on a continuous long-term simulation of a watershed driven by a historical meteorological database. The HFAM model is used to assess potential changes in the timing and volume of streamflow by driving the model with a long-term meteorological database that has been altered to represent the future climate in a specific year, for a given climate change scenario. In the Tuolumne, historical trends show increases to daily minimum temperatures but not to daily maximum temperatures. A static meteorological database that represents the current climate condition is generated by removing trends from historical data. Climate change scenarios for paired changes in temperature and precipitation were developed based on the range of predictions by global climate models. For each future climate condition, hourly temperature increases to the static database are calculated that are consistent with historical trends in daily minimum temperatures, while retaining a reasonable daily range in temperatures. Changes in future seasonal and annual probabilistic inflow forecasts are given for the Tuolumne River for each climate change scenario. The results show the importance of using probabilistic methods to assess climate change rather than mean values because impacts are more significant in low streamflow years.

Kenward, T.; Crawford, N. H.; Dufour, A.; McGurk, B. J.; Monier, W.

2011-12-01

15

Options for including all lands in a future greenhouse gas accounting framework  

Microsoft Academic Search

The current framework through which greenhouse gas emissions and removals in the land use sector are accounted under the Kyoto Protocol has several problems. They include a complex structure, onerous monitoring and reporting requirements, and potential for omission of some important fluxes. One solution that may overcome some of these problems is to include all lands and associated processes within

Annette L. Cowie; Miko U. F. Kirschbaum; Murray Ward

2007-01-01

16

Depressive Symptoms, Including Lack of Future Orientation, as Mediators in the Relationship between Adverse Life Events and Delinquent Behaviors  

Microsoft Academic Search

The present study provided a cross-sectional examination of associations among adverse life events, depressive symptoms, and delinquency in a community sample of 123 early adolescent boys and girls. We also examined whether depressive cognitions, including hopelessness, differentially mediated the relations between exposure to adverse events and delinquent behaviors. Depressive cognitions, especially lack of future orientation, were associated with delinquent behaviors

Maureen A. Allwood; Carly Baetz; Sarah DeMarco; Debora J. Bell

2012-01-01

17

Including land use, land-use change, and forestry in future climate change, agreements: thinking outside the box  

Microsoft Academic Search

This paper presents a framework that encompasses a full range of options for including land use, land-use change, and forestry (LULUCF) within future agreements under the United Nations Convention on Climate Change (UNFCCC). The intent is to provide options that can address the broad range of greenhouse gas (GHG) emissions and removals as well as to bring the broadest possible

R. Benndorf; S. Federici; C. Forner; N. Pena; E. Rametsteiner; M. J. Sanz; Z. Somogyi

2007-01-01

18

Report on the American Nuclear Society International Topical Meeting: {open_quotes}The safety, status, and future of non-commercial reactors and irradiation Facilities{close_quotes}  

Microsoft Academic Search

The American Nuclear Society`s International Topical Meeting, The Safety, Status, and Future of Non-Commercial Reactors and Irradiation Facilities, also known as SAFOR 90, was held in Boise, Idaho, September 30 to October 4, 1990. In 19 half-day sessions, 102 papers were presented which covered operating research reactors, production reactors, the use of reactors for training and research, probabilistic risk assessments

1991-01-01

19

Energy and environmental research emphasizing low-rank coal: Task 3.4 -- Hot-gas cleaning. Topical report (includes semiannual report for January--June 1995)  

SciTech Connect

This report summarizes the accomplishments of three subtasks completed in support of the current and future hot-gas cleanup activities at the Energy and Environmental Research Center (EERC). The overall objective of the EERC hot-gas cleanup task is to develop reliable methods to remove particulate matter from high-temperature, high-pressure gas streams produced from coal combustion and/or gasification. Near-term task objectives include (1) design, fabrication, and assembly of a high-temperature, high-pressure bench-scale filter vessel; (2) design, fabrication, and assembly of a high-temperature, high-pressure sampling train; and (3) the preliminary design of a pilot-scale high-temperature, high-pressure filter vessel and support systems. Bench-scale hot-gas filter research will be performed with the pressurized fluid-bed reactor (PFBR) or the continuous fluid-bed reactor (CFBR) and a hot-gas filter vessel. The objectives of future work with the bench-scale system will be to determine particulate and vapor-phase alkali degradation of candidate ceramic filter structures as well as filter performance relative to particulate collection efficiency, differential pressure, and filter cleanability. Construction of the high-temperature, high-pressure sampling system was intended to support bench- and pilot-scale activities with respect to conventional particulate sampling (total mass and particle-size distribution) and hazardous air pollutant (HAP) sampling. Finally, pilot-scale tests will be performed to evaluate filter performance and determine alkali corrosion of ceramic materials with a hot-gas filter vessel attached to the EERC Transport Reactor Development Unit (TRDU).

Weber, G.F.; Swanson, M.L.

1995-06-01

20

The Evaluation of Topical Intralesional and Systemic Antiviral Agents, Including Interferon and Interferon Inducers, in Experimental Animal Model Viral Skin Infections.  

National Technical Information Service (NTIS)

Acyclovir (ACV) was able to prevent the fatal outcome of herpes simplex virus-induced skin infections of the lumbosacral or orofacial area in hairless mice. Topical ACV treatment was more effective than systemic treatment in preventing the evolution of sk...

A. E. Friedman-Kien R. J. Klein

1979-01-01

21

Live Science: Hot Topics  

NSDL National Science Digital Library

This website from Live Science looks at a multitude of topics and the latest news and/or inventions in the topic. Topics include: Nanotechnolgy, Science, Robots, Biotechnology, Inventions, Technology and more. Each page includes a collection of resources on each topic.

2012-08-03

22

Health Topics  

MedlinePLUS

... Home > A-Z Health Topics A-Z Health Topics This information in Spanish ( en espańol ) Health information ... information on a wide range of women's health topics. Find your topic by first letter: A B ...

23

The human brain at stage 17, including the appearance of the future olfactory bulb and the first amygdaloid nuclei.  

PubMed

The growth of the cerebral hemispheres rostrally and caudodorsally brings about a deepening of the interlongitudinal fissure, in which blood capillaries for the future choroid plexus develop. Accumulation of mesenchyme basally presages the formation of the nasal septum. The olfactory bulb and tubercle become outlined. The three main areas of the telencephalon, future archi-, paleo-, and neocortex, can be recognized. The amygdaloid body, which is related to the medial ventricular eminence, contains either one or two nuclei. Nerve fibres from the olfactory tubercle arrive and pass through the amygdaloid area. The first indication of a septal nucleus is recognizable. The lateral ventricular eminence is present but not pronounced. The hemispheric stalk joins the cerebral hemispheres to the ventral thalamus and to the diencephalic part of the medial ventricular eminence. The beginning of the future choroid plexus consists in the formation of blood vessels and necrotic changes in the roof of the telencephalon medium and in rostral growth of the anterior choroid artery. Necrotic processes in the future choroid epithelium are now localized at the periphery of the still multilaminar tissue. The sulcus medius and zona intrathalamica delimit the dorsal from the ventral thalamus. The dimesencephalic borderline passes through the commissural fibres in the roof: the rostral part of the commissure is the posterior commissure, the caudal part, the commissure of the superior colliculi. In the mesencephalon, the red nucleus has a laterorostral position with regard to the nucleus of the oculomotor nerve. The cells of the locus coeruleus are well distinguishable. The gustatory fibres begin to separate from the common afferent tract as the tractus solitarius. Inferior and superior salivatory nuclei are delineated. PMID:2802187

Müller, F; O'Rahilly, R

1989-01-01

24

Developmental Toxicity Evaluation for Sodium Thioglycolate (CAS No. 367-51-1) Administered Topically to New Zealand White Rabbits on Gestational Days 6 through 29 (Includes Laboratory Supplement).  

National Technical Information Service (NTIS)

The thioglycolic acids, which include the salt sodium thioglycolate, have widespread occupational and consumer exposure because of their use in cosmetics and hair-care products. As constituents of those types of products, their use is predominantly focuse...

R. W. Tyl

2001-01-01

25

Headache Topics  

MedlinePLUS

Home » My Headache » Headache Topic Sheets Headache Topic Sheets Consumer Topics Consumer Medications Spanish Abdominal Migraine Acupuncture Alcohol and Headaches Allergy and Headaches Analgesic Rebound Anemia Arteriovenous Malformation Arthritis Aura Basilar ...

26

Freshman Health Topics  

ERIC Educational Resources Information Center

|This article examines a cluster of health topics that are frequently selected by students in lower division classes. Topics address issues relating to addictive substances, including alcohol and tobacco, eating disorders, obesity, and dieting. Analysis of the topics examines their interrelationships and organization in the reference literature.…

Hovde, Karen

2011-01-01

27

Freshman Health Topics  

ERIC Educational Resources Information Center

This article examines a cluster of health topics that are frequently selected by students in lower division classes. Topics address issues relating to addictive substances, including alcohol and tobacco, eating disorders, obesity, and dieting. Analysis of the topics examines their interrelationships and organization in the reference literature.…

Hovde, Karen

2011-01-01

28

Estradiol Topical  

MedlinePLUS

Estradiol topical gel and emulsion (lotion type mixture) are used to treat and prevent hot flushes (hot flashes; ... of life; the end of monthly menstrual periods). Estradiol topical gel is also used to treat vaginal dryness, ...

29

Popular Topics  

Center for Food Safety and Applied Nutrition (CFSAN)

... Popular Topics. This section provides links to information on popular topics like fruit juice, raw milk, seafood, trans fat, and energy drinks. ... Trans Fat. -. ... More results from www.fda.gov/food/populartopics

30

Text Segmentation by Topic  

Microsoft Academic Search

. We investigate the problem of text segmentation by topic.Applications for this task include topic tracking of broadcast speech dataand topic identification in full-text databases. Researchers have tackledsimilar problems before but with different goals. This study focuses ondata with relatively small segment sizes and for which within-segmentsentences have relatively few words in common making the problem challenging.We present a method

Jay M. Ponte; W. Bruce Croft

1997-01-01

31

Topic in Depth - Subways  

NSDL National Science Digital Library

Many cities around the world offer subways as a primary mode of public transportation. These subway systems are not only major accomplishments in civil engineering, but have a rich history. This Topic in Depth explores the technology, history, and future of subways.

2010-09-16

32

Oxybutynin Topical  

MedlinePLUS

Oxybutynin topical gel is used to control frequent urination, urgent need to urinate, and urge urinary incontinence (sudden strong need to ... bladder even when it is not full). Oxybutynin gel is in a class of medications called anticholinergics. ...

33

Fluorouracil Topical  

MedlinePLUS

... caused by years of too much exposure to sunlight). Fluorouracil cream and topical solution are also used ... plan to avoid unnecessary or prolonged exposure to sunlight and UV light (such as tanning booths) and ...

34

Short List of Topics for Prioritizing and Defining Future Work Related to Health Sector Non-Governmental Organizations. Special Initiatives Report No. 13.  

National Technical Information Service (NTIS)

This report provides a short list of topics and activities related to the role of non-governmental organizations (NGOs) in health sector reform and health service delivery. The Partnerships for Health Reform (PHR) developed this list to help prioritize th...

A. Wouters D. DeRoeck

1998-01-01

35

Work Requirements in Transformation, Competence for the Future: A Critical Look at the Consequences of Current Positions. IAB Labour Market Research Topics No. 45.  

ERIC Educational Resources Information Center

|In Germany and elsewhere, the literature on current and future work requirements rarely discusses the effects of globalization, internationalization, computerization, and other factors from the point of view of workers. Some have suggested that a blurring of limits will be one of the main changes in work in the future. This blurring will involve…

Plath, Hans-Eberhard

36

Early use of corrective lenses in Spanish colonies of the Americas including parts of the future United States: reference to Viceroy Luis de Velasco (the Son).  

PubMed

We discuss many aspects of a reproduction of a formal painting from the XVIth century. It is a portrait of Viceroy of New Spain Luis de Velasco, El Joven or Hijo (son-see text), found at the Museum of the Pecos National Monument (near Pecos and Santa Fe, New Mexico). A formal portrait of each Viceroy of New Spain was created, and this one was painted during de Velasco's first term as Viceroy (1590 to 1595 AD). In this depiction, he is seen wearing spectacles. To our knowledge, this is the first known reference suggesting the introduction of this form of visual correction in the Spanish Colonies in the Americas and in the future United States. There are three known portraits of Luis de Velasco (son): One painting, which included his father and significant others, hangs in the Colegiata (a small cathedral) de San Luis near Valladolid, Spain. In this portrayal, he was shown as a young man without a spectacle correction. And there are two viceregal portraits (Term 1, 1590 to 1595; Term 2, 1607 to 1611) in which he wears the same spectacle correction (these are located in Mexico City). PMID:14560118

Calvo, Maria; Enoch, Jay M

2003-10-01

37

The role of natural gas as a primary fuel in the near future, including comparisons of acquisition, transmission and waste handling costs of as with competitive alternatives.  

PubMed

Natural gas comprises about a quarter of the United States' energy use. It is more environmentally friendly than oil and coal due to lower carbon dioxide (CO2) emissions per unit, less costly per unit of energy and more readily available domestically in abundant supply. However, due to a number of barriers in the political, infrastructural, pricing and other arenas, the use of natural gas as a significant energy source in the United States has been limited. In our paper, we highlight the favorable qualities of natural gas and its benefits for the consumer, producer, and environment, having compared the costs of the various components of the natural gas business such as drilling and transport to that of coal and oil. Moreover, we touch upon the major issues that have prevented a more prevalent use of the gas, such as the fact that the infrastructure of natural gas is more costly since it is transported though pipelines whereas other energy sources such as oil and coal have flexible systems that use trains, trucks and ships. In addition, the powerful lobbies of the coal and oil businesses, along with the inertia in the congress to pass a national climate change bill further dampens incentives for these industries to invest in natural gas, despite its various attractive qualities. We also include discussions of policy proposals to incentive greater use of natural gas in the future. PMID:22540989

Liang, Fang-Yu; Ryvak, Marta; Sayeed, Sara; Zhao, Nick

2012-04-23

38

Tretinoin Topical  

MedlinePLUS

Tretinoin is used to treat acne. It promotes peeling of affected skin areas and unclogs pores. Tretinoin controls acne but does not cure it.This ... Tretinoin comes in topical liquid, cream, and gel. Tretinoin usually is used daily at bedtime or once ...

39

RESEARCH TOPICS  

Microsoft Academic Search

On energy technology side, Dr. Vahidi's interests are in fuel cell power systems, hybrid electric systems and distributed energy generation. Fuel cells pose challenging problems both in modeling and identification; and while the topic is interesting from a control engineering perspective, it also opens an interdisciplinary means of collaboration with people in thermodynamics, fluid mechanics, material science, chemistry and electrical

1986-01-01

40

Topical Botulinum Toxin  

PubMed Central

Nanotechnology is a rapidly growing discipline that capitalizes on the unique properties of matter engineered on the nanoscale. Vehicles incorporating nanotechnology have led to great strides in drug delivery, allowing for increased active ingredient stability, bioavailability, and site-specific targeting. Botulinum toxin has historically been used for the correction of neurological and neuromuscular disorders, such as torticollis, blepharospasm, and strabismus. Recent dermatological indications have been for the management of axillary hyperhydrosis and facial rhytides. Traditional methods of botulinum toxin delivery have been needle-based. These have been associated with increased pain and cost. Newer methods of botulinum toxin formulation have yielded topical preparations that are bioactive in small pilot clinical studies. While there are some risks associated with topical delivery, the refinement and standardization of delivery systems and techniques for the topical administration of botulinum toxin using nanotechnology is anticipated in the near future.

Collins, Ashley

2010-01-01

41

Topical fluoride guidance  

Microsoft Academic Search

Scope and purposeTo review the scientific evidence and develop clinical recommendations on professionally applied topical fluoride.MethodologyMedline and the Cochrane Database of Systematic Reviews were searched for systematic reviews published in the English language that dealt with professionally applied topical fluoride, including gel, foam or varnish, at any time up to October 2005. Seventeen systematic reviews were identified. Clinical studies published

Derek Richards

2006-01-01

42

Topical therapies for psoriasis  

PubMed Central

OBJECTIVE To review current understandings of and approaches to topical psoriasis therapies and to assess their efficacies and adverse effects. QUALITY OF EVIDENCE Literature from 1987 to 2003, inclusive, was reviewed via MEDLINE using the search term “psoriasis” combined with “topical treatment.” Articles were prioritized based on their level of evidence, favouring double-blind, randomized controlled trials over other comparison studies. Other studies were included where level I research was unavailable. No level III research was included. MAIN MESSAGE Psoriasis is very common and causes substantial morbidity. Because most psoriasis is mild to moderate, patients are well suited to outpatient topical therapy. Advances in topical treatments for psoriasis have kept pace with a rapidly evolving comprehension of its pathogenesis, making a review of current therapies useful for those who treat psoriasis. While research supports continued reliance on corticosteroids as first-line therapy, comparable efficacy has been shown for vitamin D analogues and topical retinoids, albeit with a slight increase in adverse effects. CONCLUSION The combination of steroids and vitamin D analogues or topical retinoids is perhaps the most promising current treatment. It seems to have increased efficacy and fewer side effects.

Afifi, Tarek; de Gannes, Gillian; Huang, Changzheng; Zhou, Youwen

2005-01-01

43

An investigation comparing traditional recitation instruction to computer tutorials which combine three-dimensional animation with varying levels of visual complexity, including digital video in teaching various chemistry topics  

NASA Astrophysics Data System (ADS)

This study examines the effect of increasing the visual complexity used in computer assisted instruction in general chemistry. Traditional recitation instruction was used as a control for the experiment. One tutorial presented a chemistry topic using 3-D animation showing molecular activity and symbolic representation of the macroscopic view of a chemical phenomenon. A second tutorial presented the same topic but simultaneously presented students with a digital video movie showing the phenomena and 3-D animation showing the molecular view of the phenomena. This experimental set-up was used in two different experiments during the first semester of college level general chemistry course. The topics covered were the molecular effect of heating water through the solid-liquid phase change and the kinetic molecular theory used in explaining pressure changes. The subjects used in the experiment were 236 college students enrolled in a freshman chemistry course at a large university. The data indicated that the simultaneous presentation of digital video, showing the solid to liquid phase change of water, with a molecular animation, showing the molecular behavior during the phase change, had a significant effect on student particulate understanding when compared to traditional recitation. Although the effect of the KMT tutorial was not statistically significant, there was a positive effect on student particulate understanding. The use of computer tutorial also had a significant effect on student attitude toward their comprehension of the lesson.

Graves, A. Palmer

44

The Future of Public Broadcasting.  

ERIC Educational Resources Information Center

This script of "National Town Meeting," a public affairs program on National Public Radio, contains a panel discussion on the future of public broadcasting, during which panel members also answer questions from the audience. The topics discussed include programming and program content, production costs, public participation, funding, the influence…

Bachrach, Judy

45

Emission scenarios for air quality management and applications at local and regional scales including the effects of the future European emission regulation (2015) for the upper Rhine valley  

Microsoft Academic Search

Air quality modeling associated with emission scenarios has become an important tool for air quality man- agement. The set-up of realistic emission scenarios requires accurate emission inventories including the whole method- ology used to calculate the emissions. This means a good description of the source characteristics including a detailed composition of the emitted fluxes. Two main approaches are used. The

J.-L. Ponche; J.-F. Vinuesa

2005-01-01

46

Additional Topics  

NSDL National Science Digital Library

This subset of the Black Box Software Testing collection includes resources to teach quality cost analysis, combination testing, regression testing, GUI regression automation, high volume test automation, requirements analysis, test documentation, test scripts, and scripted testing and inattentional blindness. Resources include lecture videos, slides, activities, and suggested readings.

Kaner, Cem; Fiedler, Rebecca L.

2011-06-01

47

Teacher Topics.  

ERIC Educational Resources Information Center

|Includes articles and classroom activities about chemicals in the body entitled: "Your Body's Chemical Factory,""Testing for Catalase Activity,""How Sweet It IS...,""Milking Calcium for All It's Worth," and "Testing for Starch in Plant Products." (MKR)|

Chemecology, 1995

1995-01-01

48

Critically appraised topics.  

PubMed

This article describes the critically appraised topic (CAT) as a means to disseminate evidence from research literature to rehabilitation professionals. A CAT is a standardized, one-page summary of research evidence organized around a clinical question. A CAT includes a clinical bottom line that reflects synthesis of a research article and clinical application of the results. The synthesis includes a critique of the internal, external, and statistical validity of the research. The process of writing CATs has been used in the preparation of evidence-based practitioners. Commonly used websites for preparation and posting of CATs are included as well as an example of a CAT on the topic of cerebral palsy. PMID:17057467

Fetters, Linda; Figueiredo, Elyonara M; Keane-Miller, Devon; McSweeney, Debra J; Tsao, Cheng-Chi

2004-01-01

49

Esther Dyson's Vision of the Future.  

ERIC Educational Resources Information Center

|Discusses a vision of the future based on Esther Dyson's views of the proliferation of the Internet. Topics include the Internet as a communication medium; electronic commerce; the role of education, including the role of teachers; intellectual property rights; and friction freedom in a new digital economy relating to pricing. (LRW)|

Runyan, Andy

1999-01-01

50

Commodity Futures & Financial Market Charts  

NSDL National Science Digital Library

This site, a product of TFC Commodity Charts, provides daily, monthly and weekly price charts for various commodity and financial futures. These include grains, meats, energy, metals, exchange rate and interest rate futures. There is also a short course introducing beginners to commodity market trading. The course covers topics from the origins of commodity trading to the operations of a commodity market. Beginners will be interested in the glossary of commodity futures terms provided at the site as well. Note that these are not realtime charts.

51

Futures Conditional.  

ERIC Educational Resources Information Center

|The readings presented here are designed to help the reader perceive the future more vividly. Part one of the book suggests the various ways in which the future can be seen; it includes science fiction and the views of various analysts as to what the future holds. Part two collects printed materials about the future from various sources,…

Theobald, Robert

52

Emission scenarios for air quality management and applications at local and regional scales including the effects of the future European emission regulation (2015) for the upper Rhine valley  

NASA Astrophysics Data System (ADS)

Air quality modeling associated with emission scenarios has become an important tool for air quality management. The set-up of realistic emission scenarios requires accurate emission inventories including the whole methodology used to calculate the emissions. This means a good description of the source characteristics including a detailed composition of the emitted fluxes. Two main approaches are used. The so-called bottom-up approach that relies on the modification of the characteristics of the sources and the top-down approach whose goal is generally to reach standard pollutant concentration levels. This paper is aimed at providing a general methodology for the elaboration of such emission scenarios and giving examples of applications at local and regional scales for air quality management. The first example concerns the impact of the installation of the urban tramway in place of the road traffic in the old centre of Strasbourg. The second example deals with the use of oxygenated and reformulated car fuels on local (Strasbourg urban area) and regional (upper Rhine valley) scales. Finally, we analyze in detail the impacts of the incoming European emission regulation for 2015 on the air quality of the upper Rhine valley.

Ponche, J.-L.; Vinuesa, J.-F.

2005-03-01

53

Emission scenarios for air quality management and applications at local and regional scales including the effects of the future European emission regulation (2015) for the upper Rhine valley  

NASA Astrophysics Data System (ADS)

Air quality modeling associated with emission scenarios has become an important tool for air quality management. The set-up of realistic emission scenarios requires accurate emission inventories including the whole methodology used to calculate the emissions. This means a good description of the source characteristics including a detailed composition of the emitted fluxes. Two main approaches are used. The so-called bottom-up approach that relies on the modification of the characteristics of the sources and the top-down approach whose goal is generally to reach standard pollutant concentration levels. This paper is aimed at providing a general methodology for the elaboration of such emission scenarios and giving examples of applications at local and regional scales for air quality management. The first example concerns the impact of the installation of the urban tramway in place of the road traffic in the old centre of Strasbourg. The second example deals with the use of oxygenated and reformulated car fuels on local (Strasbourg urban area) and regional (upper Rhine valley) scales. Finally, we analyze in detail the impacts of the incoming European emission regulation for 2015 on the air quality of the upper Rhine valley.

Ponche, J.-L.; Vinuesa, J.-F.

2004-12-01

54

Topics for Current and Future Consideration  

ERIC Educational Resources Information Center

|What lies ahead for nontraditional doctorate programs? What issues should concern administrators, faculty, and scholars? Faculty and administrators raised concerns that the marketplace demand for "nontraditional doctoral programs" would pollute the academic purity and sanctity of traditional programs. The authors provide some considerations for…

Pappas, James P.; Jerman, Jerry

2011-01-01

55

Topical and oral bexarotene.  

PubMed

Bexarotene is a retinoid that specifically binds retinoid X receptors and has numerous effects on cellular growth and differentiation. It is approved for the treatment of cutaneous T cell lymphoma both topically and systemically. Adverse effects include hyperlipidemia, central hypothyroidism, and neutropenia with bexarotene capsules, and an irritant dermatitis with bexarotene gel. With aggressive management of these potential side effects, bexarotene is an additional option in the armamentarium for management of cutaneous T cell lymphoma. PMID:24099070

Schadt, Courtney R

2013-09-01

56

Teaching Biochemistry: A Topical Approach.  

ERIC Educational Resources Information Center

Uses the subject of enzymes to illustrate the topical approach to teaching biochemistry at the secondary level. Includes the procedures for three experiments dealing with various aspects of enzymes. (JN)

Maier, Mary L.

1986-01-01

57

A Theme-Based Course: Hydrogen as the Fuel of the Future  

ERIC Educational Resources Information Center

|A theme-based course focusing on the potential role of hydrogen as a future fuel is described. Numerous topics included in typical introductory courses can be directly related to the issue of hydrogen energy. Beginning topics include Avogadro's number, the mole, atomic mass, gas laws, and the role of electrons in chemical transformations.…

Shultz, Mary Jane; Kelly, Matthew; Paritsky, Leonid; Wagner, Julia

2009-01-01

58

Social media futures: why iSchools should care  

Microsoft Academic Search

Social Media Futures was a 3 day charrette at a major university that brought together students with various backgrounds to consider the future impact of social media on business, and to think about what opportunities that might create. However, topics that arose touched on a variety of themes that included social media communities, ownership, privacy and governance of user-generated content

Michael J. Scialdone; Anthony J. Rotolo; Jaime Snyder

2011-01-01

59

Marine actinobacteria: perspectives, challenges, future directions  

Microsoft Academic Search

In this paper we evaluate the current state of research on the biology and biotechnology of marine actinobacteria. The topics covered include the abundance, diversity, novelty and biogeographic distribution of marine actinobacteria, ecosystem function, bioprospecting, and a new approach to the exploration of actinobacterial taxonomic space. An agenda for future marine actinobacterial research is suggested based upon consideration of the

Alan T Bull; James E. M Stach; Alan C Ward; Michael Goodfellow

2005-01-01

60

The Future of Physics in Scottish Schools  

ERIC Educational Resources Information Center

|Reports on a one day meeting organized by the Scottish Branch of the Institute of Physics. The main topic was the future of physics teaching in schools. It included an analysis of the present situation in science, input from company recruiters and college professors, and possible solutions to present problems. (GS)|

Jardine, J. T.; And Others

1974-01-01

61

Teaching about the Future Is No Joke.  

ERIC Educational Resources Information Center

|Presents teaching methods and learning activities to help social studies classroom teachers as they develop legal education programs with a futures orientation. Topics include the power of the courts, the media and the law, juvenile justice, government regulation of advertising, and legal assistance. Questions, games, and vocabulary exercises are…

Gerlach, Ronald A.

1980-01-01

62

Topical report review status  

SciTech Connect

This report provides industry with procedures for submitting topical reports, guidance on how the U.S. Nuclear Regulatory Commission (NRC) processes and responds to topical report submittals, and an accounting, with review schedules, of all topical reports currently accepted for review schedules, of all topical reports currently accepted for review by the NRC. This report will be published annually. Each sponsoring organization with one or more topical reports accepted for review copies.

NONE

1997-08-01

63

Hot topics from the Tevatron  

SciTech Connect

The Tevatron Run-II began in March 2001. To date, both the CDF and D0 experiments have collected 1 fb{sup -1} of data each. The results obtained from this data set were summarized at this conference in 39 parallel session presentations covering a wide range of topics. The author summarizes the most important of those results here and comments on some of the prospects for the future.

Glenzinski, D.; /Fermilab

2008-01-01

64

Health physics of radiation generating machines 20th midyear topical symposium  

Microsoft Academic Search

These proceedings contain papers on various topics in health physics of radiation generating machines, including diagnostic x-ray procedures; special medical procedures; radiation therapy; dosimetry and instrumentation; industrial applications; fusion and confinement devices; proton machines; heavy ions; electron accelerators, rings, and devices; very high energy machines; and future prospects and links between physics and medicine.

W. P. Swanson; D. D. Busick

1987-01-01

65

FDA Hot Topics  

Center for Biologics Evaluation and Research (CBER)

Text VersionFDA Hot Topics. Alan E. Williams, Ph.D. ... January 27-29, 2010. FDA Hot topics. The Office of Blood Research and Review (OBRR), CBER. ... More results from www.fda.gov/downloads/biologicsbloodvaccines/newsevents

66

Topic One: “minimal risk”  

Center for Biologics Evaluation and Research (CBER)

Text VersionPage 1. Topic One: “minimal risk” • Please discuss the application of the concept of minimal risk ... than minimal? 1 Page 2. Topic One: “minimal risk” ... More results from www.fda.gov/downloads/advisorycommittees/committeesmeetingmaterials

67

Content Management and the Future of Academic Libraries.  

ERIC Educational Resources Information Center

|Discusses Internet-based electronic content management in digital libraries and considers the future of academic libraries. Topics include digital technologies; content management systems; standards; bandwidth; security and privacy concerns; legal matters, including copyrights and ownership; lifecycle; and multilingual access and interface. (LRW)|

Wu, Yuhfen Diana; Liu, Mengxiong

2001-01-01

68

Topical treatment of ichthyoses.  

PubMed

Management of ichthyoses is a complex and continuously dynamic process. Primary treatments of ichthyosis are by means of topical moisturizers and topical medications. Patients and families need to have reasonable and realistic expectations when it comes to topical therapy. Topical medications cannot cure the scaling, but can gradually reduce it and thus improve their condition. No one treatment regimen works for everyone, and the best topical therapy for each patient may be the result of months (or years) of painstaking effort on both the physician's and the patient's behalf. As patients get older and their activities and lifestyles change, so should their topical treatment regimen. Bear in mind that the more complex the skin care regimen and costly the topical treatments, the less likely a patient and their family will be compliant. PMID:23384017

Fleckman, Philip; Newell, Brandon D; van Steensel, Maurice A; Yan, Albert C

69

Major research topics in combustion  

SciTech Connect

The Institute for Computer Applications in Science and Engineering (ICASE) and NASA Langley Research Center (LaRC) hosted a workshop on October 2--4, 1989 to discuss some combustion problems of technological interest to LaRC and to foster interaction with the academic community in these research areas. The topics chosen for this purpose were flame structure, flame holding/extinction, chemical kinetics, turbulence-kinetics interaction, transition to detonation, and reacting free shear layers. This document contains the papers and edited versions of general discussions on these topics. The lead paper set the stage for the meeting by discussing the status and issues of supersonic combustion relevant to the scramjet engine. Experts were then called upon to review the current knowledge in the aforementioned areas, to focus on how this knowledge can be extended and applied to high-speed combustion, and to suggest future directions of research in these areas.

Hussaini, M.Y.; Kumar, A.; Voigt, R.G. (eds.)

1992-01-01

70

Identifying topic sentencehood  

Microsoft Academic Search

Four experiments were conducted to assess two models of topic sentencehood identification: the derived model and the free model. According to the derived model, topic sentences are identified in the context of the paragraph and in terms of how well\\u000a each sentence in the paragraph captures the paragraph’s theme. In contrast, according to the free model, topic sentences can\\u000a be

Philip M. McCarthy; Adam M. Renner; Michael G. Duncan; Nicholas D. Duran; Erin J. Lightman; Danielle S. McNamara

2008-01-01

71

Haloprogin: a Topical Antifungal Agent  

PubMed Central

Haloprogin was shown to be a highly effective agent for the treatment of experimentally induced topical mycotic infections in guinea pigs. Its in vitro spectrum of activity also includes yeasts, yeastlike fungi (Candida species), and certain gram-positive bacteria. The in vitro and in vivo antifungal activity of haloprogin against dermatophytes was equal to that observed with tolnaftate. The striking differences between the two agents were the marked antimonilial and selective antibacterial activities shown by haloprogin, contrasted with the negligible activities found with tolnaftate. Addition of serum decreased the in vitro antifungal activity of haloprogin to a greater extent than that of tolnaftate; however, diminished antifungal activity was not observed when haloprogin was applied topically to experimental dermatophytic infections. Based on its broad spectrum of antimicrobial activity, haloprogin may prove to be a superior topical agent in the treatment of dermatophytic and monilial infections in man.

Harrison, E. F.; Zwadyk, P.; Bequette, R. J.; Hamlow, E. E.; Tavormina, P. A.; Zygmunt, W. A.

1970-01-01

72

Haloprogin: a topical antifungal agent.  

PubMed

Haloprogin was shown to be a highly effective agent for the treatment of experimentally induced topical mycotic infections in guinea pigs. Its in vitro spectrum of activity also includes yeasts, yeastlike fungi (Candida species), and certain gram-positive bacteria. The in vitro and in vivo antifungal activity of haloprogin against dermatophytes was equal to that observed with tolnaftate. The striking differences between the two agents were the marked antimonilial and selective antibacterial activities shown by haloprogin, contrasted with the negligible activities found with tolnaftate. Addition of serum decreased the in vitro antifungal activity of haloprogin to a greater extent than that of tolnaftate; however, diminished antifungal activity was not observed when haloprogin was applied topically to experimental dermatophytic infections. Based on its broad spectrum of antimicrobial activity, haloprogin may prove to be a superior topical agent in the treatment of dermatophytic and monilial infections in man. PMID:5422306

Harrison, E F; Zwadyk, P; Bequette, R J; Hamlow, E E; Tavormina, P A; Zygmunt, W A

1970-05-01

73

USGS Science Topics  

NSDL National Science Digital Library

This topical directory provides an alternate way to browse United States Geological Survey (USGS) science programs and activities. It is not an exhaustive list of all USGS science topics but provides a categorization using a thesaurus of related terms that will give definitions, links to science content, and a structured approach to discovery. The directory is divided into fourteen major topic headings, each with an associated listing of subtopics and related topics. USGS websites that have been identified as primary portals are always shown first. Remaining search results appear in order of decreasing priority as matches against a list of criteria applied to their titles.

74

CSA Hot Topics Series  

NSDL National Science Digital Library

The Hot Topics series provides a free sampling of the resources in Cambridge Scientific Abstracts (CSA) and the Internet Database Service (IDS). The 30 topics span subjects in the humanities, engineering, environmental policy, and medicine. Each Hot Topic gives an overview of the subject, key citations with abstracts, a list of Websites, a glossary, a comment form so that users can correspond with the editors, and a "source" section, which explains from which of CSA's paid services the resources were culled. The latest hot topic is MicroElectroMechanical systems (MEMS), "small integrated devices or systems that combine electrical and mechanical components."

75

TOPICAL REVIEW: Biopolymeric nanoparticles  

NASA Astrophysics Data System (ADS)

This review on nanoparticles highlights the various biopolymers (proteins and polysaccharides) which have recently revolutionized the world of biocompatible and degradable natural biological materials. The methods of their fabrication, including emulsification, desolvation, coacervation and electrospray drying are described. The characterization of different parameters for a given nanoparticle, such as particle size, surface charge, morphology, stability, structure, cellular uptake, cytotoxicity, drug loading and drug release, is outlined together with the relevant measurement techniques. Applications in the fields of medicine and biotechnology are discussed along with a promising future scope.

Sundar, Sushmitha; Kundu, Joydip; Kundu, Subhas C.

2010-02-01

76

Choosing a Research Topic  

NSDL National Science Digital Library

This website from the Chronicle of Higher Education features tips for graduate students on choosing a research topic. The author explains a variety of ways that a topic should be matched to the individual. A good choice can help lead to long-term career success.

Reis, Richard M.; Education, The C.

77

Identifying Topics by Position  

Microsoft Academic Search

This paper addresses the problem of iden- tifying likely topics of texts by their posi- tion in the text. It describes the automated training and evaluation of an Optimal Posi- tion Policy, a method of locating the likely positions of topic-bearing sentences based on genre-specific regularities of discourse structure. This method can be used in applications such as information retrieval,

Chin-yew Lin; Eduard H. Hovy

1997-01-01

78

Dynamic topic models  

Microsoft Academic Search

A family of probabilistic time series models is developed to analyze the time evolution of topics in large document collections. The approach is to use state space models on the natural param- eters of the multinomial distributions that repre- sent the topics. Variational approximations based on Kalman filters and nonparametric wavelet re- gression are developed to carry out approximate posterior

David M. Blei; John D. Lafferty

2006-01-01

79

Correlated Topic Models  

Microsoft Academic Search

Topic models, such as latent Dirichlet allocation (LDA), have been an ef- fective tool for the statistical analysis of document collections and other discrete data. The LDA model assumes that the words of each document arise from a mixture of topics, each of which is a distribution over the vo- cabulary. A limitation of LDA is the inability to model

David M. Blei; John D. Lafferty

2005-01-01

80

US Support Program Topical Meetings 1999 to 2008  

SciTech Connect

In 1999, the International Safeguards Project Office began organizing topical workshops to explore technical issues facing the International Atomic Energy Agency's Department of Safeguards. Representatives from IAEA member states including the United States, national laboratories and companies were invited to the workshops to discuss the technical issues. In some cases professional facilitators were hired to lead the discussions and in some cases business gaming techniques were employed. Since 1999, the following topics have been addressed Data Communication Technologies (1999), Information Security (2000), Design and Testing for High Reliability (2001), Standardization and Integration of Unattended and Remote Monitoring Systems (2002), Roadmapping: Surveillance (2003), IAEA Seals Technology Roadmapping Workshop (2004), Turning Information Into Knowledge (2004), Safeguards Tools of the Future (2005), and Advanced Sensors for Safeguards (2007). This paper will review the scope of the workshops and summarize their results.

Pepper,S.

2008-06-10

81

Educational Technology in Turkey: Past, Present and Future.  

ERIC Educational Resources Information Center

|Explains the past, discusses the present, and makes projections for the future of educational technology in Turkey. Topics include historical background of Turkey and of educational technology in Turkey; the role of the Ministry of National Education; distance education; technology-based education; and the national information infrastructure.…

Akkoyunlu, Buket

2002-01-01

82

Bacterial resistance and topical antimicrobial wash products  

Microsoft Academic Search

Current scientific evidence has not shown that a link exists between the use of topical antimicrobial formulations and antiseptic or antibiotic resistance. As a result of the extensive history and varied use of antiseptic products and ingredients, any selective pressure for antibiotic resistance that may be occurring or may be uncovered in the future because of antiseptic use would be

Rhonda D. Jones

1999-01-01

83

PREFACE: CEWQO Topical Issue CEWQO Topical Issue  

Microsoft Academic Search

This topical issue of Physica Scripta collects selected peer-reviewed contributions based on invited and contributed talks and posters presented at the 15th Central European Workshop on Quantum Optics (CEWQO) which took place in Belgrade 29 May-3 June 2008 (http:\\/\\/cewqo08.phy.bg.ac.yu). On behalf of the whole community took place in Belgrade 29 May-3 June 2008 (http:\\/\\/cewqo08.phy.bg.ac.yu, cewqo08.phy.bg.ac.yu). On behalf of the whole

Mirjana Bozic; Margarita Man'ko

2009-01-01

84

Tentative Topics for Discussion  

Center for Biologics Evaluation and Research (CBER)

Text VersionPage 1. Topics for Discussion At the meeting, FDA will present to the Advisory Committee some of the requirements related ... More results from www.fda.gov/downloads/advisorycommittees/committeesmeetingmaterials

85

Topical Anesthetics - Overview  

Center for Drug Evaluation (CDER)

... health advisory to alert you to the potential hazards of using skin-numbing products, also known as topical anesthetics, for cosmetic procedures. ... More results from www.fda.gov/drugs/drugsafety/drugsafetypodcasts

86

PDUFA IV Update Topics  

Center for Drug Evaluation (CDER)

Text VersionPage 1. PDUFA IV Update Gary M Gensinger Deputy Director, Office of Business Process Support Center for Drug Evaluation and Research Topics ... More results from www.fda.gov/downloads/drugs/developmentapprovalprocess

87

Topic in Depth - Gyroscopes  

NSDL National Science Digital Library

This Topic in Depth explores gyroscopes and gyroscopic effect, from introductory materials about how gyroscopes are used in bicycles to research and commercial applications to hypothetical uses, such as in Rosie the Robot from The Jetsons cartoon.

2010-09-14

88

Salicylic Acid Topical  

MedlinePLUS

... skin dryness and scaling), dandruff, corns, calluses, and warts on the hands or feet. Topical salicylic acid should not be used to treat genital warts, warts on the face, warts with hair growing ...

89

IP Internal Movement and Topicalization  

ERIC Educational Resources Information Center

In this dissertation, I investigate the phenomenon of internal topicalization cross-linguistically, using Chinese as a starting point. Internal topicalization refers to constructions in which a topic phrase is placed between the subject and the verb (in contrast to external topicalization, which involves a topic in the CP domain). I argue that…

Kuo, Pei-Jung

2009-01-01

90

IP Internal Movement and Topicalization  

ERIC Educational Resources Information Center

|In this dissertation, I investigate the phenomenon of internal topicalization cross-linguistically, using Chinese as a starting point. Internal topicalization refers to constructions in which a topic phrase is placed between the subject and the verb (in contrast to external topicalization, which involves a topic in the CP domain). I argue that…

Kuo, Pei-Jung

2009-01-01

91

Advanced topics in finite element analysis  

SciTech Connect

These proceedings collect papers on finite element analysis. Topics include: finite element welding computations, nonlinear analysis codes, computation of 3D transient solid dynamics, enhanced graphics processing, parallel architectures for graphics, and the display of finite elements using animation.

Cory, J.F.; Gordon, J.L.

1988-01-01

92

Topical Relevance Relationships. II. An Exploratory Study and Preliminary Typology.  

ERIC Educational Resources Information Center

|Reports on an empirical investigation of relationship types. User needs are back-generated from randomly selected subject headings employed in a user-oriented topical concordance. Topical relevance includes matching, paradigmatic, or syntagmatic relationships, and more. (AEF)|

Green, Rebecca; Bean, Carol A.

1995-01-01

93

Nuclear Chemistry: Include It in Your Curriculum.  

ERIC Educational Resources Information Center

Some of the topics that might be included in a nuclear chemistry section are explored. Offers radioactivity, closed shells in nuclei, energy of nuclear processes, nuclear reactions, and fission and fusion as topics of interest. Provided are ideas and examples for each. (MVL)

Atwood, Charles H.; Sheline, R. K.

1989-01-01

94

Nuclear Chemistry: Include It in Your Curriculum.  

ERIC Educational Resources Information Center

|Some of the topics that might be included in a nuclear chemistry section are explored. Offers radioactivity, closed shells in nuclei, energy of nuclear processes, nuclear reactions, and fission and fusion as topics of interest. Provided are ideas and examples for each. (MVL)|

Atwood, Charles H.; Sheline, R. K.

1989-01-01

95

February 12, 2013: Discussion Topics  

Center for Biologics Evaluation and Research (CBER)

... and Drug Administration. -. February 12, 2013: Discussion Topics. -. February 12, 2013: Topics (PDF - 31KB). -. -. -. Page Last Updated ... More results from www.fda.gov/advisorycommittees/committeesmeetingmaterials/riskcommunicationadvisorycommittee

96

June 29, 2012: Discussion Topics  

Center for Biologics Evaluation and Research (CBER)

... and Drug Administration. -. June 29, 2012: Discussion Topics. -. Discussion Topics (PDF - 52KB). -. -. -. Page Last Updated ... More results from www.fda.gov/advisorycommittees/committeesmeetingmaterials/riskcommunicationadvisorycommittee

97

Reading Tea Leaves: How Humans Interpret Topic Models  

Microsoft Academic Search

Probabilistic topic models are a popular tool for the unsupervised analysis of text, providing both a predictive model of future text and a latent topic representation of the corpus. Practitioners typically assume that the latent space is semantically meaningful. It is used to check models, summarize the corpus, and guide explo- ration of its contents. However, whether the latent space

Jonathan Chang; Jordan Boyd-Graber; Sean Gerrish; Chong Wang; David M. Blei

98

PREFACE: CEWQO Topical Issue CEWQO Topical Issue  

NASA Astrophysics Data System (ADS)

This topical issue of Physica Scripta collects selected peer-reviewed contributions based on invited and contributed talks and posters presented at the 15th Central European Workshop on Quantum Optics (CEWQO) which took place in Belgrade 29 May-3 June 2008 (http://cewqo08.phy.bg.ac.yu). On behalf of the whole community took place in Belgrade 29 May-3 June 2008 (http://cewqo08.phy.bg.ac.yu, cewqo08.phy.bg.ac.yu). On behalf of the whole community of the workshop, we thank the referees for their careful reading and useful suggestions which helped to improve all of the submitted papers. A brief description of CEWQO The Central European Workshop on Quantum Optics is a series of conferences started informally in Budapest in 1992. Sometimes small events transform into important conferences, as in the case of CEWQO. Professor Jozsef Janszky, from the Research Institute of Solid State Physics and Optics, is the founder of this series. Margarita Man'ko obtained the following information from Jozsef Janszky during her visit to Budapest, within the framework of cooperation between the Russian and Hungarian Academies of Sciences in 2005. He organized a small workshop on quantum optics in Budapest in 1992 with John Klauder as a main speaker. Then, bearing in mind that a year before Janszky himself was invited by Vladimir Buzek to give a seminar on the same topic in Bratislava, he decided to assign the name 'Central European Workshop on Quantum Optics', considering the seminar in Bratislava to be the first workshop and the one in Budapest the second. The third formal workshop took place in Bratislava in 1993 organized by Vladimir Buzek, then in 1994 (Budapest, by Jozsef Janszky), 1995 and 1996 (Budmerice, Slovakia, by Vladimir Buzek), 1997 (Prague, by Igor Jex), 1999 (Olomouc, Czech Republic, by Zdenek Hradil), 2000 (Balatonfüred, Hungary, by Jozsef Janszky ), 2001 (Prague, by Igor Jex), 2002 (Szeged, Hungary, by Mihaly Benedict), 2003 (Rostock,Germany, by Werner Vogel and Sascha Wallentowitz), 2004 (Trieste, Italy, by Naseem Rahman and Sascha Wallentowitz), 2005 (Bilkent, Ankara, by Alexander Shumovsky), 2006 (Vienna, by Helmut Rauch), 2007 (Palermo, Italy, by Antonino Messina) and 2008 (Belgrade, by Mirjana Bozic). The CEWQO series developed in two directions following the rapid development of quantum optics and the transitional development of the scientific collaboration of Central European researchers with researchers from old and new emerging Central European countries, and from all over the world. The topics discussed at CEWQO 08 were divided into ten groups that aimed to cover the broad scope of modern quantum optics: Fundamental aspects of quantum optics and quantum mechanics Single photons and photon pairs Cavity and circuit QED Atoms in intense fields Neutron, atom and molecular quantum optics Quantum gases and fluids Coherence, entanglement and decoherence Optical properties of condensed matter and nanostructures Open quantum systems and chaos Quantum information processing Central European Workshops on Quantum Optics realize and are consistent with a wider idea, and a social, economical, cultural and political program promoted since 1989 by the Central European Initiative (CEI), the main goal of which was to help transition countries in Central Europe to become closer to the EU. The resulting support of the CEI, first obtained thanks to the scientific reputation, organizing activities, and efforts of Helmut Rauch, has been very important for the organization of the CEWQO in recent years, particularly in 2008. The support of the Sixth and Seventh Framework Programs of the European Commission was also very important. A short review of papers in this topical issue A principal role in this topical issue is played by the photon. Vuletic et al describe the mapping of the photon-polarization state onto a single collective-spin excitation (magnon) shared between two atomic ensembles. A heralded quantum memory based on this mapping is demonstrated. Dodonov derives a formula which predicts a photon generation rate in a cavity due to

Bozic, Mirjana; Man'ko, Margarita

2009-09-01

99

Topics for Mathematics Clubs.  

ERIC Educational Resources Information Center

|The ten chapters in this booklet cover topics not ordinarily discussed in the classroom: Fibonacci sequences, projective geometry, groups, infinity and transfinite numbers, Pascal's Triangle, topology, experiments with natural numbers, non-Euclidean geometries, Boolean algebras, and the imaginary and the infinite in geometry. Each chapter is…

Dalton, LeRoy C., Ed.; Snyder, Henry D., Ed.

100

Topics in electronic ceramics  

Microsoft Academic Search

Four topics in the field of electronic ceramics are reviewed: multilayer ceramic capacitors, piezoelectric ceramics, electrooptic ceramics, and ferroelectric thin films. They all are related to ferroelectric ceramic materials. The scope of this review is limited to oxide compounds, because oxide ferroelectrics, for the most part, exhibit the most useful properties and have found the most applications. The underlying physical

S. L. Swartz

1990-01-01

101

Essay Test Topic Development.  

ERIC Educational Resources Information Center

Extensive research efforts in the past decade have measured academic proficiency and progress in both theory and practice of large-scale writing assessment. The following major situational variables were identified in these investigations: (1) topic variables such as writing prompts, subject matter, mode of discourse, length, and rhetorical…

Brossell, Gordon

102

Topic in Depth - Antimatter  

NSDL National Science Digital Library

For every action there is a reaction, for every plus there is a minus, and for every matter there is wellâ¦antimatter. This topic in depth tackles the complex concept of antimatter, from the Big Bang to solar explosions and the technology to detect it.

2010-09-15

103

Topic in Depth - Telematics  

NSDL National Science Digital Library

Often used in mobile telephony, vehicle tracking, online navigation, and emergency assistance, the design of wireless systems for the collection and dissemination of data is known as telematics. This Topic in Depth offers definitions, research information, and the uses of the technology in industry.

2010-09-16

104

The Author-Topic Model for Authors and Documents  

Microsoft Academic Search

We introduce the author-topic model, a gen- erative model for documents that extends La- tent Dirichlet Allocation (LDA; Blei, Ng, & Jordan, 2003) to include authorship informa- tion. Each author is associated with a multi- nomial distribution over topics and each topic is associated with a multinomial distribution over words. A document with multiple au- thors is modeled as a

Michal Rosen-Zvi; Thomas L. Griffiths; Mark Steyvers; Padhraic Smyth

2004-01-01

105

Blaha suggests need for future research on the effects of isolation and confinement.  

PubMed

Astronaut John Blaha's stay aboard the Mir space station is described. He arrived on STS-79 for a four-month stay. Topics include the psychological effects of living in cramped quarters and social isolation. Suggestions for future research that includes participants from different cultures are presented. PMID:12190064

1997-06-01

106

Australia's IT&T Future: A Strategic Analysis Report 1 July 1998.  

ERIC Educational Resources Information Center

|Summarizes the GartnerGroup's views on issues in the information technology and telecommunications (IT&T) industry debate in Australia. Topics include attracting overseas investment to create a globally competitive industry; the government's role; perceived problems; the Internet and electronic commerce; and future issues, including leadership.…

Australian Library Journal, 1998

1998-01-01

107

Topical microbicides--what's new?  

PubMed

Topical microbicides are an important, promising but complex HIV prevention technology under development. After 11 disappointing effectiveness trial outcomes of 6 candidate products (some tested as multiple doses and formulations) over the past 20 years, there is renewed optimism that a safe and effective microbicide will soon be available if the recent success of coitally linked use of the antiretroviral-based microbicide, 1% tenofovir gel, is confirmed. Studies of new antiviral agents, novel delivery mechanisms, and combination/multipurpose products that address challenges of adherence, enhance the effectiveness of tenofovir gel, and address sexual and reproductive health needs of men and women, including preventing HIV infection, are already underway. PMID:23764627

Karim, Quarraisha Abdool; Baxter, Cheryl; Karim, Salim Abdool

2013-07-01

108

Dave Young's Chemical Topics  

NSDL National Science Digital Library

This collection of articles from Dave Young of Cytoclonal Pharmaceutics covers select topics in computational chemistry (e.g., molecular vibrations, pharmaceuticals, spin contamination), magnetochemistry, states of matter, and Gaussian, Mopac, and Unix computer languages. The articles are plucked from Young's publication Computational Chemistry: A Practical Guide for Applying Techniques to Real World Problems, scheduled to be published by John Wiley & Sons this spring. the articles are intended to be introductory and don't go into topics in depth, but some of the discussions are actually fairly advanced. The introductory section features a nice discussion of the terms "theoretical" and "computational" chemistry, with a warning of the pitfalls of relying too much on strictly computational methods. This is an interesting, informative resource for teachers of college-level chemistry.

Young, David C., 1964-

2001-01-01

109

LiveScience Topic: Nanotechnology  

NSDL National Science Digital Library

So what is nanotechnology, you ask? Nanotechnology is defined as the science and technology of building electronic circuits and devices from single atoms and molecules, or the branch of engineering that deals with things smaller than 100 nanometers. This site details the future benefits that nanotechnology research could serve including advances in telecommunications, information technology, healthcare and pharmaceuticals. For additional information on nanotechnology, what it consists of, as well as nanotech's current and future impacts on the world of science, simply select any nanotechnology article or other interactive feature.

2010-11-26

110

Topic in Depth - Chlorine  

NSDL National Science Digital Library

Chlorine, a chemical element whose name means âÂÂpale green,â is explored from a number of angles in this informative Topic in Depth.WeâÂÂve all heard of chlorine being used in swimming pools and drinking water, but this jack-of-all-trades chemical element is also used in making everything from plastics and dry cleaning products to insecticides and pharmaceuticals.

2010-09-15

111

Topic in Depth - Voice over Internet Protocol  

NSDL National Science Digital Library

Voice over Internet protocol (VoIP) is a technology that integrates voice services, such as those provided by long distance telephone carriers, into data networks. This Topic in Depth presents information about the development and future of VoIP. VoIP has received considerable attention in recent years since it blurs the line between telecommunications and Internet. Among other things, it has the potential for enabling virtually free person-to-person communication for anyone with an Internet connection.

2010-09-16

112

Progress in structural materials for aerospace systems 1 1 The Golden Jubilee Issue—Selected topics in Materials Science and Engineering: Past, Present and Future, edited by S. Suresh  

Microsoft Academic Search

This paper examines the progress in aircraft and aircraft engines from the standpoint of the role that better materials and processing has played. Such progress includes the relatively recent transformation of the aircraft industry from purely performance driven products to products that are driven by customer value. It is demonstrated that advances in materials and processing technology and understanding has

James C Williams; Edgar A Starke

2003-01-01

113

Current topics in nail surgery  

PubMed

BACKGROUND: Nail surgery can be performed in an office-based dermatology practice with a limited amount of specialized equipment and training. Several excellent reviews have been published in recent years that detail the techniques of nail surgery for both the novice and the experienced practitioner. OBJECTIVE: In this article recent developments in nail surgery are discussed. Topics that are treated include the general principles of nail surgery, including epidemiologic issues, studies of nail anatomy, instrumentation, and anesthesia. The reconstruction of injuries and congenital defects involving the nail is explained, and the role of the hand surgeon clarified. Appropriate removal of tumours and cysts is considered, with special attention to the management of malignant lesions. The controversy regarding more or less conservative management of melanonychia striata is addressed, and the need for early diagnosis of subungual melanoma is emphasized. Other topics are surgical management of ingrown nails and onychomycosis. Newer areas of nail surgery, such as laser surgery of the nail, psychodermatology of the nail, and the role of primary care physicians in simple nail surgery are also examined. PMID:10575165

Alam; Scher

1999-10-01

114

Neutron transport simulation (selected topics)  

NASA Astrophysics Data System (ADS)

Neutron transport simulation is usually performed for criticality, power distribution, activation, scattering, dosimetry and shielding problems, among others. During the last fifteen years, innovative technological applications have been proposed (Accelerator Driven Systems, Energy Amplifiers, Spallation Neutron Sources, etc.), involving the utilization of intermediate energies (hundreds of MeV) and high-intensity (tens of mA) proton accelerators impinging in targets of high Z elements. Additionally, the use of protons, neutrons and light ions for medical applications (hadrontherapy) impose requirements on neutron dosimetry-related quantities (such as kerma factors) for biologically relevant materials, in the energy range starting at several tens of MeV. Shielding and activation related problems associated to the operation of high-energy proton accelerators, emerging space-related applications and aircrew dosimetry-related topics are also fields of intense activity requiring as accurate as possible medium- and high-energy neutron (and other hadrons) transport simulation. These applications impose specific requirements on cross-section data for structural materials, targets, actinides and biologically relevant materials. Emerging nuclear energy systems and next generation nuclear reactors also impose requirements on accurate neutron transport calculations and on cross-section data needs for structural materials, coolants and nuclear fuel materials, aiming at improved safety and detailed thermal-hydraulics and radiation damage studies. In this review paper, the state-of-the-art in the computational tools and methodologies available to perform neutron transport simulation is presented. Proton- and neutron-induced cross-section data needs and requirements are discussed. Hot topics are pinpointed, prospective views are provided and future trends identified.

Vaz, P.

2009-10-01

115

[Topical treatment of psoriasis: a systematic update].  

PubMed

Classical topical treatment regimens in psoriasis including dithranol and corticosteroids are widely used and have been supplemented in recent years by topical vitamin D preparations, by vitamin D analogues and topical retinoids. The combination of these preparations with each other, with UV light or with systemic drugs often lead to improved effectiveness and tolerability when compared with the respective monotherapy. In private offices, the combination of calcipotriol with various corticosteroids is very commonly prescribed for patients with mild to moderate psoriasis. This combination can be sequentially applied twice daily or--in a newly introduced fixed preparation--once daily. In severe psoriasis requiring systemic treatment a concomitant effective topical treatment regimen can greatly improve the overall longtime management in affected patients. PMID:12634992

Aschoff, R; Wozel, G; Meurer, M

2003-02-13

116

Special Topic in Criminal Justice: ORGANIZED CRIME  

Microsoft Academic Search

This course examines the societal problem of enterprise crime, more commonly referred to as organized crime (OC). An interdisciplinary perspective is taken, which includes addressing a series of key legal, law enforcement and social issues, with a focus on Canadian OC in comparative perspective as well as from a business or enterprise perspective. Topics covered will include: the concept and

Course Outline

117

Topics in CP violation  

SciTech Connect

Given the varied backgrounds of the members of this audience this talk will be a grab bag of topics related to the general theme of CP Violation. I do not have time to dwell in detail on any of them. First, for the astronomers and astrophysicists among you, I want to begin by reviewing the experimental status of evidence for CP violation in particle processes. There is only one system where this has been observed, and that is in the decays of neutral K mesons.

Quinn, H.R.

1993-02-01

118

Topic in Depth - Aerodynamics  

NSDL National Science Digital Library

Aerodynamics is the study of what makes things go fast, right? More specifically, itâÂÂs the study of the interaction between bodies and the atmosphere. This topic in depth highlights some fun websites on the science of aerodynamics, for beginners to researchers. If youâÂÂve been watching Wimbeldon lately, you might have been wondering about the aerodynamics of tennis. Or maybe you were riding your bike the other day and wondering how you could pick up a little more speed next time. These sites can help explain.

2010-09-17

119

Topic Two: “disorder or condition”  

Center for Biologics Evaluation and Research (CBER)

Text VersionPage 1. Topic Two: “disorder or condition” • Please discuss the application of the concepts of “disorder” ... 1 Page 2. Topic Two: “disorder or condition” ... More results from www.fda.gov/downloads/advisorycommittees/committeesmeetingmaterials

120

Health Topics: MedlinePlus  

MedlinePLUS

... features on this page, please enable JavaScript. Health Topics Read about symptoms, causes, treatment and prevention for ... illnesses, health conditions and wellness issues. MedlinePlus health topics are regularly reviewed, and links are updated daily. ...

121

Symbiosis: Rich, Exciting, Neglected Topic  

ERIC Educational Resources Information Center

|Argues that the topic of symbiosis has been greatly neglected and underemphasized in general-biology textbooks. Discusses many types and examples of symbiosis, and provides an extensive bibliography of the literature related to this topic. (JR)|

Rowland, Jane Thomas

1974-01-01

122

How Astronomers Can Help Prepare Future Teachers  

NASA Astrophysics Data System (ADS)

Classroom teachers are expected to teach a variety of astronomical topics, yet research indicates that most undergraduates do not have a scientific understanding of these topics, and there is widespread misunderstanding as to the nature of science. How can astronomers help to prepare the next generation of teachers in space science? Our group has met with teacher educators from both science and education departments, and conducted a survey to better understand the role and needs for astronomy in teacher pre-service. We will share the current research and the results of our own survey of teacher educators, and some of the models and suggestions that the members of the NASA Science Mission Directorate’s Pre-Service Education Working Group (http://www.lpi.usra.edu/education/score/pre_service.shtml) have discovered. Research has shown that effective teaching practices need to be modeled--future teachers need to be taught a subject the way they will be teaching it in their classrooms. Our survey of teacher educators (from science and education departments at a variety of colleges across the US) suggests educators are concerned that today's future teachers are not taught science in college as inquiry-based, with activities that model the nature of investigation. The survey also indicated that future elementary teachers often have a fear or dislike of science, and do not understand the nature of science, and that students do not have enough breadth in science subjects. Our group's meetings and discussions have discerned a variety of opportunities for astronomers to effect change in the future classroom teacher. These include changing the way that classes are taught, increasing opportunities for future teachers (in addition to future scientists) to have true scientific research experiences, creating scientist-education partnerships to improve science pre-service education, and establishing programs with scientists as mentors to future teachers.

Shupla, Christine; Ruberg, L.; Slater, T. F.; Schultz, G.

2006-12-01

123

University of Iowa Hospitals Health Topics  

NSDL National Science Digital Library

Created by staff members at the University of Iowa Hospitals and Clinics, the materials on this website include articles and patient guides that cover health topics such as colon cancer, burn care, ear health, and eating disorders. The page is part of their larger health library site, and visitors can scroll through the topic list here, which includes over two dozen headings. One rather nice section is the "Healthy Recipes" area, which features breakfast recipes for items like buckwheat pancakes and banana nut bread. Visitors also shouldn't forget to look at the "Sports Medicine" area where they will find answers to commonly asked questions about torn ankle ligaments and ACL problems.

124

Recent developments in topical thrombins.  

PubMed

Managing blood loss is part of the surgeon's responsibility during surgical procedures, and a variety of therapeutic strategies are available to help accomplish this. Topical haemostatic agents are among the agents used to control surgical bleeding and locally arrest blood flow. Bovine thrombin is a commonly used topical haemostatic agent; however, its use has been associated with potential risks, including well-documented cases of antibody-mediated coagulopathy. This coagulopathy develops as a consequence of antibody formation directed against bovine thrombin, other bovine coagulation proteins, and their human orthologs. The fact that a coagulopathy can result in association with the use of bovine plasma-derived thrombin preparations prompted the FDA to require pharmaceutical companies to place a black-box warning in their prescribing information for products containing bovine plasma-derived thrombin. Recently, human plasma-derived thrombin and recombinant human thrombin have been approved by the FDA with the expectation that they will be less immunogenic than the bovine-derived product. In clinical studies, purified human plasma-derived thrombin and recombinant thrombin have demonstrated equivalent efficacy and safety, with improved immunogenicity profiles compared with bovine-derived thrombin agents. Well-designed and adequately powered clinical trials should be conducted to indicate whether human thrombin products would improve the risk-benefit and cost-benefit profiles for surgeries complicated by excessive bleeding. PMID:19572062

Kessler, Craig M; Ortel, Thomas L

2009-07-01

125

TOPICAL REVIEW Nanoscale memory devices  

NASA Astrophysics Data System (ADS)

This article reviews the current status and future prospects for the use of nanomaterials and devices in memory technology. First, the status and continuing scaling trends of the flash memory are discussed. Then, a detailed discussion on technologies trying to replace flash in the near-term is provided. This includes phase change random access memory, Fe random access memory and magnetic random access memory. The long-term nanotechnology prospects for memory devices include carbon-nanotube-based memory, molecular electronics and memristors based on resistive materials such as TiO2.

Chung, Andy; Deen, Jamal; Lee, Jeong-Soo; Meyyappan, M.

2010-10-01

126

Preparing Students for a Changing Future: How One New York School District Restructured Its Educational Focus with Technology.  

ERIC Educational Resources Information Center

|Describes how to restructure education to better prepare students for the future based on the plan developed at the South Huntington Union Free School District (New York). Topics include the need for a paradigm shift in education; technology as a tool for learning, including interactive courseware; inservice teacher training; the home-school…

Lauber, Gerald

1997-01-01

127

Mapping Ethical Consumer Behavior: Integrating the Empirical Research and Identifying Future Directions  

Microsoft Academic Search

The concept of “ethical consumer behavior” has gained significant attention among practitioners and academic researchers, generating increasing but disjointed knowledge on the topic. By analyzing the empirical research on ethical consumer behavior, this article provides researchers with a map to guide future research. In total, we review 80 studies. The main contributions of the article include the identification of the

Eleni Papaoikonomou; Gerard Ryan; Mireia Valverde

2011-01-01

128

The North American Collections Inventory Project: Implications for the Future of Coordinated Management of Research Collections.  

ERIC Educational Resources Information Center

Describes the accomplishments of a cooperative effort to develop an online inventory of research library collections. Topics covered include the development of collection mapping tools and resources; the establishment of general requirements and policies; and the implications for the future of coordinated management of research collections. (20…

Farrell, David; Reed-Scott, Jutta

1989-01-01

129

Beyond Structures and Status--Survival Skills for Facing the Future.  

ERIC Educational Resources Information Center

|Discusses the future of libraries and the necessary steps that need to be taken to be successful. Topics discussed include the process of change, the need to emphasize delivery systems rather than storage facilities, library services, the need for strategic planning, the role of technology, and library leadership. (11 references) (LRW)|

Penniman, W. David

1991-01-01

130

Mining nonterrestrial resources: Information needs and research topics  

NASA Astrophysics Data System (ADS)

An outline of topics we need to understand better in order to apply mining technology to a nonterrestrial environment is presented. The proposed list is not intended to be complete. It aims to identify representative topics that suggest productive research. Such research will reduce the uncertainties associated with extrapolating from conventional earthbound practice to nonterrestrial applications. One objective is to propose projects that should put future discussions of nonterrestrial mining on a firmer, less speculative basis.

Daemen, Jaak J. K.

131

Ecotechnological Solutions for Slope Stability: Perspectives for Future Research  

Microsoft Academic Search

This chapter concludes the work presented in this book. Future research topics are proposed which include suggestions for\\u000a developing a database of plant species useful for erosion control and slope stability. Decision support systems also need\\u000a more work and should be available for the general practitioner to use without specialist training. Field studies and numerical\\u000a modelling should be combined to

Alexia Stokes

132

Thymoma classification: current status and future trends.  

PubMed

The classification of thymic epithelial neoplasms has been a controversial topic for many years. Recent advances in diagnostic methods and renewed interest in the biology of these tumors has led to efforts by investigators to shed new light on their biologic behavior and to offer novel perspectives on these unusual neoplasms. Several new classification schemes have been proposed, including the new World Health Organization schema for the histologic typing of tumors of the thymus. We review the current status of thymoma classification and comment on problem areas and future trends that may offer a more pragmatic approach to these tumors. PMID:16627265

Suster, Saul; Moran, Cesar A

2006-04-01

133

Dietary therapies for epilepsy: future research.  

PubMed

Since 1921, dietary therapies have remained valuable options in the treatment of intractable childhood epilepsy. The traditional ketogenic diet has been well demonstrated, including in a recent randomized, controlled trial, as being highly effective. More recent alternative diets such as the medium-chain triglyceride diet, modified Atkins diet, and low-glycemic-index treatment have expanded the use of this modality to more children as well as adults. In this review, we discuss our top 10 most pressing research topics related to the ketogenic diet that warrant future study. As well, two promising ketogenic diet clinical researchers discuss their past and current research to help answer some of these questions. PMID:21441072

Kessler, Sudha K; Neal, Elizabeth G; Camfield, Carol S; Kossoff, Eric H

2011-03-26

134

Water: A Topic for All Sciences  

Microsoft Academic Search

The authors illustrate an effective lessonplanning technique known as unpacking for the broad topic of water. Interconnections among science disciplines are shown for numerous possible subtopics. Two lesson sets are included, the first dealing with properties of water and the second dealing with water as a resource.

Malonne I. Davies; C. Matt Seimears

2008-01-01

135

Physical Review Special Topics : Accelerators and Beams  

NSDL National Science Digital Library

Current and past issues of this free American Physical Society peer-reviewed, electronic journal are available here. The journal is published on an article-by-article basis, and new articles are added to the latest issue. March titles in Physical Review Special Topics--Accelerators and Beams include "Coherent off-axis undulato radiation from short electron bunches."

136

Quark-gluon plasma (Selected Topics)  

NASA Astrophysics Data System (ADS)

Introductory lectures to the theory of (strongly interacting) quark-gluon plasma given at the Winter School of Physics of ITEP (Moscow, February 2010). We emphasize theoretical issues highlighted by the discovery of the low viscosity of the plasma. The topics include relativistic hydrodynamics, manifestations of chiral anomaly in hydrodynamics, superfluidity, relativistic superfluid hydrodynamics, effective stringy scalars, holographic models of Yang-Mills theories.

Zakharov, V. I.

2012-09-01

137

Quark-gluon plasma (Selected Topics)  

SciTech Connect

Introductory lectures to the theory of (strongly interacting) quark-gluon plasma given at the Winter School of Physics of ITEP (Moscow, February 2010). We emphasize theoretical issues highlighted by the discovery of the low viscosity of the plasma. The topics include relativistic hydrodynamics, manifestations of chiral anomaly in hydrodynamics, superfluidity, relativistic superfluid hydrodynamics, effective stringy scalars, holographic models of Yang-Mills theories.

Zakharov, V. I., E-mail: vzakharov@itep.ru [Institute for Theoretical and Experimental Physics (Russian Federation)

2012-09-15

138

Teaching Difficult Topics with Primary Sources  

ERIC Educational Resources Information Center

|"Difficult" or "challenging" topics to teach include racism, violence, genocide, bullying, gangs, abuse (physical, emotional, and substance), slavery, suffering, hatred, terrorism, war, disease, loss, addiction, and more. But by confronting them with students, in the safety of a classroom through thoughtfully constructed lessons (ones that take…

Potter, Lee Ann

2011-01-01

139

Sea Changes. Topics in Marine Earth Science.  

ERIC Educational Resources Information Center

|This publication is designed for use in standard science curricula to develop oceanologic manifestations of certain science topics. Included are teacher guides, student activities, and demonstrations designed to impart ocean science understanding to high school students. The principal theme of Changes in the Sea is presented in this particular…

Awkerman, Gary L.

140

Environmental Topics for Introductory Physics Courses  

ERIC Educational Resources Information Center

|Presents selected environmental references with comparatively detailed descriptions for the purpose of helping high school and college physics teachers in selecting materials for their course. The topics include thermal pollution, space heating and cooling, atmospheric temperature distribution, radiation balance of the earth, sound and noises,…

Hodges, Laurent

1974-01-01

141

HOT RESEARCH TOPICS FOR LEAD CONTROL  

EPA Science Inventory

This presentation is a review of important new concepts and research results that state regulators, utilities and consultants should be aware of. The topics covered include sampling issues, importance of oxidants to lead and copper levels, Pb(IV) occurrence and implications, unus...

142

Topics in statistical mechanics  

SciTech Connect

This thesis deals with four independent topics in statistical mechanics: (1) the dimer problem is solved exactly for a hexagonal lattice with general boundary using a known generating function from the theory of partitions. It is shown that the leading term in the entropy depends on the shape of the boundary; (2) continuum models of percolation and self-avoiding walks are introduced with the property that their series expansions are sums over linear graphs with intrinsic combinatorial weights and explicit dimension dependence; (3) a constrained SOS model is used to describe the edge of a simple cubic crystal. Low and high temperature results are derived as well as the detailed behavior near the crystal facet; (4) the microscopic model of the lambda-transition involving atomic permutation cycles is reexamined. In particular, a new derivation of the two-component field theory model of the critical behavior is presented. Results for a lattice model originally proposed by Kikuchi are extended with a high temperature series expansion and Monte Carlo simulation. 30 references.

Elser, V.

1984-05-01

143

Composition for topical application to skin  

US Patent & Trademark Office Database

A composition for topical application to an animal's skin for relief from a variety of symptoms caused by medical conditions or physical injuries. The composition includes at least one compound having analgesic activity, at least one compound having anti-inflammatory activity, at least one compound having antioxidant activity, at least one compound having anti-neuralgic activity, at least one compound having blood circulation promotion activity, and at least one compound having antidepressant activity. A method for relieving pain by topical application of the composition is also provided.

McClung; Jackie H. (Oklahoma City, OK)

2003-06-17

144

Update on topical antibiotics in dermatology.  

PubMed

Topical antibiotics are used for various purposes in dermatology. Some of the most common uses include treatment of acne, treatment and prevention of wound infection(s), impetigo or impetiginized dermatitis, and staphylococcal nasal carrier state. It is important for the dermatologist to be familiar with the spectrum of activity, the mechanism of action, and the variables that may interfere with the antibiotic of choice. The following discussion will review an update on topical antibiotic use in acne, wound care, impetigo, and in staphylococcal nasal carriers. PMID:22591495

Drucker, Carol R

145

Topical corticosteroid use during pregnancy  

PubMed Central

Abstract Question Some of my pregnant patients have been prescribed various potencies of topical corticosteroids. Do these carry the same fetal risks as systemic corticosteroids? Answer Pregnant women can be reassured that there is no apparent increased risk of adverse fetal effects when using topical corticosteroids during pregnancy, although some data do suggest fetal growth restriction with more potent topical corticosteroids. Overall, women should be prescribed the lowest potency required whenever possible.

Alabdulrazzaq, Fatoumah; Koren, Gideon

2012-01-01

146

Topical medications: A focus on antifungals and topical steroids  

Microsoft Academic Search

Because skin disease is accessible, it can be treated with locally applied medication, which offers great advantages-exposure to a drug is limited to the affected skin and systemic effects of potentially toxic drugs are minimized. Ointments, creams, antifungals, and antibiotics all have their place in treating various skin diseases. Topical steroids, the largest group of topical medications, are effective but

Guy F. Webster

2001-01-01

147

The future of health futures  

Microsoft Academic Search

Health futures represents the application of various futures tools to the arenas of health and health care. This special issue of Futures reflects the significant growth of health futures. Health and health-care systems can be far better by the early 21st century, or they could be worse. Health futures enables individuals, organizations and communities to understand better the threats and

Clement Bezold

1995-01-01

148

Topics in Particle Astrophysics  

NASA Astrophysics Data System (ADS)

This dissertation consists of a study of two topics in particle astrophysics. In Part I, we examine the generation of microwave background radiation fluctuations due to an inflationary epoch in the early universe. In Chapter 1, we study the angular dependence of the three-point correlation function of microwave background fluctuations. We use the standard techniques of field theory in curved spacetime to compute, up to an overall constant, the three-point function of the inflaton field varphi and relate this to the three-point function of microwave background temperature fluctuations. In Chapter 2, we study the dependence of the size of the fluctuations on the coupling constant lambda in the inflaton potential, and in particular we show that some claims in the literature that upper bounds on the size of the fluctuations do not put an upper bound on lambda are false. In Part II, we calculate the relic density of two supersymmetric particles with an eye to studying their viability as dark matter candidates. In Chapters 3 and 4, we compute corrections to the annihilation rate for binos (B) due to sfermion mixing (Chapter 3) and some loop effects (Chapter 4). We find that the effect of sfermion mixing may be large, both on the relic density of binos and their present annihilation cross-section, which affects their prospects for detection. The effect of the loop graphs we calculate is generically small, but can be large for bino masses near half the Z mass. In Chapter 5, we do a thorough calculation of the relic density of massive (_sp{~}>500 GeV) sneutrinos (~nu). We find that the relic density may lie in the cosmologically interesting region 0.1 _sp{~ }< Omega h^2 _sp{~}< 1.0 for sneutrino masses between 1 TeV and 4 TeV. Direct detection experiments require m _{~nu} _sp{~}< 2200 GeV and Omega_{~nu }h^2 _sp{~ }< 0.4.

Falk, Toby David

1994-01-01

149

Sensitive research topics: netnography revisited  

Microsoft Academic Search

Purpose – This paper discusses how netnography can be applied in order to conduct covert research on sensitive research topics. An analysis of a Danish internet message board on cosmetic surgery illustrates suggestions concerning modifications of netnography guidelines. Design\\/methodology\\/approach – Owing to the relevance of studying sensitive research topics – in particular when access to informants is difficult – netnography

Roy Langer; Suzanne C. Beckman

2005-01-01

150

Resources for Topics in Art.  

ERIC Educational Resources Information Center

|This guide for conducting library research on topics in art or the work of a particular artist presents suggestions for utilizing four categories of resources: books, dictionaries and encyclopedias, indexes, and a periodicals and serials list (PASL). Three topics are researched as examples: the contemporary artist and author Frank Stella, the…

Van Noate, Judith, Comp.

151

Topical chloramphenicol for eye infections  

Microsoft Academic Search

Topical chloramphenicol has been widely used in the treatment and prevention of superficial eye infections due to its broad spectrum of activity and low cost. The use of this drug has decreased considerably in the United States since the first case of aplastic anaemia associated with topical chloramphenicol was reported in the 1960s. This medication, however, is still widely used

DSC Lam; Sankara Nethralaya; SK Rao

152

Linguistic Extensions of Topic Models  

ERIC Educational Resources Information Center

|Topic models like latent Dirichlet allocation (LDA) provide a framework for analyzing large datasets where observations are collected into groups. Although topic modeling has been fruitfully applied to problems social science, biology, and computer vision, it has been most widely used to model datasets where documents are modeled as exchangeable…

Boyd-Graber, Jordan

2010-01-01

153

Resources for the Future: Wholesale Electricity Markets and Policy  

NSDL National Science Digital Library

In this article, Tim Brennan, a senior fellow at Resources for the Future, provides an overview of Wholesale Electricity Markets and Policy. Based in Washington, D.C., Resources for the Future (RFF), is an "independent institute dedicated exclusively to analyzing environmental, energy, and natural resource topics." (See also Scout Report from August 23, 1998.) The article is adapted from a book by Brennan published by RFF. In the article, Brennan discusses the challenges and benefits of "replacing regulation with competition" and provides an overview of the electricity market. He concludes that "while reasons for optimism exist, policy-makers should always keep in mind that electricity's crucial nature and unique characteristics may render it unsuitable for extensive competition." The Publications section includes numerous other Discussion Papers, Issue Briefs and Reports on environmental topics which are available free of charge.

Brennan, Timothy J.

154

Statement of Stephen S. Trott, Associate Attorney General, United States Department of Justice before the Select Committee on Narcotics Abuse and Control. House of Representatives concerning the Federal Government's Present and Future Efforts in Eradication, Interdiction, Law Enforcement, Education and Treatment.  

ERIC Educational Resources Information Center

|Testimony of Associate Attorney General Stephen S. Trott on the federal government's present and future efforts in drug law enforcement before the Congressional Select Committee on Narcotics Abuse and Control is presented in this document. Three topic areas are included in the testimony. The first topic of management initiatives discusses…

Department of Justice, Washington, DC.

155

Topical pimecrolimus 1% cream in the treatment of seborrheic dermatitis.  

PubMed

Seborrheic dermatitis is a multifactorial skin disease characterized by a chronic course with periods of exacerbation and remission. Although topical corticosteroids have been the mainstay of treatment, alternative therapies are often needed to avoid protracted use of topical corticosteroid therapy in order to avert side effects and to sustain control of the disorder. Topical pimecrolimus, a calcinuerin inhibitor, is a safe alternative for seborrheic dermatitis and is more ideal for long-term use. More specifically, topical pimecrolimus not only has an attractive safety profile with no risk of many of the potential side effects seen with topical corticosteroids, but also has favorable efficacy data, including more data on long-term use. This is a review of literature evaluating the efficacy and safety profile of topical pimecrolimus 1% cream for the treatment of seborrheic dermatitis. PMID:23441238

Kim, Grace K; Rosso, James Del

2013-02-01

156

Topical Pimecrolimus 1% Cream in the Treatment of Seborrheic Dermatitis  

PubMed Central

Seborrheic dermatitis is a multifactorial skin disease characterized by a chronic course with periods of exacerbation and remission. Although topical corticosteroids have been the mainstay of treatment, alternative therapies are often needed to avoid protracted use of topical corticosteroid therapy in order to avert side effects and to sustain control of the disorder. Topical pimecrolimus, a calcinuerin inhibitor, is a safe alternative for seborrheic dermatitis and is more ideal for long-term use. More specifically, topical pimecrolimus not only has an attractive safety profile with no risk of many of the potential side effects seen with topical corticosteroids, but also has favorable efficacy data, including more data on long-term use. This is a review of literature evaluating the efficacy and safety profile of topical pimecrolimus 1% cream for the treatment of seborrheic dermatitis.

Kim, Grace K.

2013-01-01

157

NCSR: Special Topics I - Forest Surveying and Silviculture  

NSDL National Science Digital Library

NCSR Special Topics I is a compilation of forestry-related topics and exercises. The materials focus on forest surveying and silvicultural methods. The materials in the manual are adaptable to technical courses in forest resource programs. They include field experiences as well as exercises to demonstrate basic and advanced concepts relevant to developing the knowledge and skills of the forest technician.

2007-05-02

158

Sexual orientation topics in educational leadership programmes across the USA  

Microsoft Academic Search

This investigation examines the inclusion of sexual orientation topics within the formal curriculum of 55 public college and university educational administration\\/leadership programmes across the USA. The findings indicate that programmes place a low priority upon sexual orientation compared to other diversity topics and that 59.5% of programmes fail to include sexual orientation as a form of diversity in their formal

Todd Jennings

2011-01-01

159

Sexual orientation topics in educational leadership programmes across the USA  

Microsoft Academic Search

This investigation examines the inclusion of sexual orientation topics within the formal curriculum of 55 public college and university educational administration\\/leadership programmes across the USA. The findings indicate that programmes place a low priority upon sexual orientation compared to other diversity topics and that 59.5% of programmes fail to include sexual orientation as a form of diversity in their formal

Todd Jennings

2012-01-01

160

Alerte Terre!: An Interactive Lecture Activity on Environmental Topics  

NSDL National Science Digital Library

In this Interactive Lecture Demonstration, students will predict the main issues that might be included in short French language videos treating topics such as endangered species, organic farming, the effect of aerosols on the environment, pollution and sustainable development. They will then view short videos on the topics and reflect on how their prior assumptions meshed with reality.

Franklin, Laura

161

Course Descriptions in Environmental Studies Part Three: Special Topics Courses.  

ERIC Educational Resources Information Center

Presents descriptions (syllabi, outlines, goals) of special topics environmental studies courses which approach the discipline from a humanistic perspective. Topic areas of these courses include: wilderness studies; biocultural patterns of population, land use, energy, and war; religion, ethics, and the environment; landscape perception; and…

Nash, Roderick; And Others

1984-01-01

162

Organic solvent topical report  

SciTech Connect

This report is the technical basis for the accident and consequence analyses used in the Hanford Tank Farms Basis for Interim Operation. The report also contains the scientific and engineering information and reference material needed to understand the organic solvent safety issue. This report includes comments received from the Chemical Reactions Subcommittee of the Tank Advisory Panel.

Cowley, W.L.

1998-04-30

163

MPI Advanced Topics  

NSDL National Science Digital Library

This module will introduce you to some of the advanced capabilities of MPI beyond ordinary message passing, including how to customize your environment in the following areas: derived datatypes; groups of processes and their associated communicators; virtual topologies among processes; and parallel I/O using MPI-IO. Application to specific architectures such as Ranger, Lonestar, etc. will be discussed.

164

The Future Is Coming: Electronic Health Records  

MedlinePLUS

... Current Issue Past Issues The Future Is Coming: Electronic Health Records Past Issues / Spring 2009 Table of ... special conference on the cutting-edge topic of electronic health records (EHR) on May 20-21, 2009, ...

165

Student voice - Tough topic.  

PubMed

ONE OF THE most difficult situations that I am involved in regularly during my training, I find, is restraining a child. In my experience so far, I have seen that restraint is generally accepted as common practice by those who care for children in hospital, even though there is evidence that the process can result in negative outcomes for all the individuals involved, including physical injuries, pain and even death. PMID:24112019

Kirwan, Lisa

2013-10-01

166

Simulator Training Requirements and Effectiveness Study (STRES): Future Research Plans.  

National Technical Information Service (NTIS)

This report, prepared for Air Force personnel responsible for the development and execution of future programs of research on the design, development, and use of aircrew training devices (ATDs), presents topics to be considered in the development of futur...

W. W. Prophet J. B. Shelnutt W. D. Spears

1981-01-01

167

Thesaurus of Common Topics (TCT): Origin, Functions, Structure.  

ERIC Educational Resources Information Center

|Discusses origin, scope, objectives, term relationships, updating, and future of "Thesaurus of Common Topics," an interdisciplinary thesaurus being developed by the Polish Centre for Scientific, Technical, and Economic Information as a main source of terms for branch thesauri development for the Polish national System of Scientific, Technical and…

Scibor, Eugeniusz; Jabrzemska, Eleonora

1985-01-01

168

Hot Topics: Alcohol  

NSDL National Science Digital Library

This Web site from the BBC provides a multi-faceted exploration of the science of alcohol. Visitors may browse eight detailed pages relating the science of alcohol production, how alcohol is absorbed and processed by the body, what happens when you've had too much, and much more. The clear yet detailed content of this site goes far to clear up alcohol-related misconceptions and misinformation. Other features include alcohol trivia, a quiz, movie and audio clips of alcohol-related BBC documentaries, links to other health Web sites for additional information, and a public message board.

2002-01-01

169

Diclofenac 1% Topical (osteoarthritis pain)  

MedlinePLUS

... feet, elbows, wrists, and hands. Diclofenac 1% topical liquid is used to relieve osteoarthritis pain in the ... only gives information about diclofenac 1% gel and liquid. If you are using the 3% product, read ...

170

Erythromycin and Benzoyl Peroxide Topical  

MedlinePLUS

The combination of erythromycin and benzoyl peroxide is used to treat acne. Erythromycin and benzoyl peroxide are in a class of medications called topical antibiotics. The combination of erythromycin and benzoyl peroxide works by killing the bacteria ...

171

Topic in Depth - Tree Troubles  

NSDL National Science Digital Library

This Topic in Depth explores some of the diseases and other threats, such as gypsy moths, emerald ash borers, and Asian longhorned beetles that certain trees must contend with to remain healthy and vital.

2010-09-14

172

Clindamycin and Benzoyl Peroxide Topical  

MedlinePLUS

The combination of clindamycin and benzoyl peroxide is used to treat acne. Clindamycin and benzoyl peroxide are in a class of medications called topical antibiotics. The combination of clindamycin ...

173

Health Topic XML File Description  

MedlinePLUS

... Supplements Videos & Cool Tools MedlinePlus Health Topic XML File Description To use the sharing features on this ... Tags - definitions of every possible tag in the file, with examples and their use on MedlinePlus. Example ...

174

The Future of Virtual Worlds  

NASA Astrophysics Data System (ADS)

This book, like the May 2008 conference in World of Warcraft, ends with projections toward what the future might hold for virtual worlds. Every chapter thus far has included speculations about future directions, even while standing on data from the past. This last chapter, like the final session of the conference on which it is based, incorporates comments from dozens of participants into a stream of ideas. We have edited selected comments together with the panel's contributions. Our intention is to provide a portal from this book into a wider virtual community comprising researchers and residents in virtual worlds. The discussion surveys many recent lines of development, some of which have already been surveyed in scientific and historical literature, or by journalists (Au 2008; Castronova 2007; Guest 2007; Ludlow and Wallace 2007). Yet, many of the topics here have not received such attention. Considered as a set of socio-technical innovations, virtual worlds are not just about technical possibilities; they also inspired the participants to consider the economic bases for investing in those possibilities and the novel cultural, social, and artistic forms virtual worlds might offer.

Bainbridge, William Sims; Lutters, Wayne; Rhoten, Diana; Lowood, Henry

175

Some hot topics in animal bioacoustics.  

PubMed

This paper is derived from a "Hot Topics in Animal Bioacoustics" presentation at the 130th meeting of the Acoustical Society of America in St. Louis, Missouri. Six bioacoustics studies on a wide variety of species are discussed. Two of the studies are concerned with insects, the parasitoid fly, and cotton bollworms. The remaining bioacoustics studies are on aquatic animals including the West Indian manatee, elephant seals, and dolphins. PMID:9165723

Au, W W

1997-05-01

176

Future accelerators (?)  

SciTech Connect

I describe the future accelerator facilities that are currently foreseen for electroweak scale physics, neutrino physics, and nuclear structure. I will explore the physics justification for these machines, and suggest how the case for future accelerators can be made.

John Womersley

2003-08-21

177

Topic-conditioned novelty detection  

Microsoft Academic Search

Automated detection of the first document reporting each new event in temporally-sequenced streams of documents is an open challenge. In this paper we propose a new approach which addresses this problem in two stages: 1) using a supervised learning algorithm to classify the on-line document stream into pre-defined broad topic categories, and 2) performing topic-conditioned novelty detection for documents in

Yiming Yang; Jian Zhang; Jaime G. Carbonell; Chun Jin

2002-01-01

178

Topic Detection Using Lexical Chains  

Microsoft Academic Search

This paper describes an algorithm for identifying the topic of unrestricted texts. The algorithm takes as input segments of\\u000a text that represent grouping of contiguous portions of the text, and discovers lex- ical chains as indicator of their topics.\\u000a Two implementation, based on public domain resources, are presented: one based on WordNet and the second one based on Roget’s\\u000a thesaurus.

Yllias Chali

2001-01-01

179

Cleaner energy for sustainable future  

Microsoft Academic Search

This special issue of the Journal of Cleaner Production focuses on “Energy for Sustainable Future”. It is designed to mirror the increasing relevance of renewable energy sources and improved efficiency as crucial topics for practitioners in industry, for governmental policy makers, as well as for civic service providers, researchers, and educators. The purpose of this special issue is to serve

Vincenzo Giorgio Dovia; Ferenc Friedler; Donald Huisingh; Ji?í Jaromír Klemeš

2009-01-01

180

The future of human spaceflight  

Microsoft Academic Search

After the Apollo Moon program, the international space station represents a further milestone of humankind in space. International follow-on programs like a manned return to the Moon and a first manned Mars Mission can be considered as the next logical step. More and more attention is also paid to the topic of future space tourism in Earth orbit, which is

M. Reichert

2001-01-01

181

Perceived importance of topics in a model foreign language in the elementary school (FLES*) methodology course  

Microsoft Academic Search

The purpose of this study was to identify topics for a model foreign language in the elementary school (FLES*) methodology course and to assess the extent to which foreign language methodology course instructors believe these topics should be included in a model FLES* methodology course curriculum.The research and literature review included topics on elementary school teacher preparation, foreign language teacher

Gilda Maureen Oran Ashbal

1990-01-01

182

Using story topics for language model adaptation  

Microsoft Academic Search

The subject matter of any conversation or document can typically be described as some combination of elemental topics. We have developed a language model adaptation scheme that t akes a piece of text, chooses the most similar topic c lusters from a set of over 5000 elemental topics, and uses topic specific language models built from the topic c lusters

Kristie Seymore; Ronald Rosenfeld

1997-01-01

183

Using NASA Space Imaging Technology to Teach Earth and Sun Topics  

NASA Astrophysics Data System (ADS)

We teach an experimental college-level course, directed toward elementary education majors, emphasizing "hands-on" activities that can be easily applied to the elementary classroom. This course, Physics 240: "The Sun-Earth Connection" includes various ways to study selected topics in physics, earth science, and basic astronomy. Our lesson plans and EPO materials make extensive use of NASA imagery and cover topics about magnetism, the solar photospheric, chromospheric, coronal spectra, as well as earth science and climate. In addition we are developing and will cover topics on ecosystem structure, biomass and water on Earth. We strive to free the non-science undergraduate from the "fear of science" and replace it with the excitement of science such that these future teachers will carry this excitement to their future students. Hands-on experiments, computer simulations, analysis of real NASA data, and vigorous seminar discussions are blended in an inquiry-driven curriculum to instill confident understanding of basic physical science and modern, effective methods for teaching it. The course also demonstrates ways how scientific thinking and hands-on activities could be implemented in the classroom. We have designed this course to provide the non-science student a confident basic understanding of physical science and modern, effective methods for teaching it. Most of topics were selected using National Science Standards and National Mathematics Standards that are addressed in grades K-8. The course focuses on helping education majors: 1) Build knowledge of scientific concepts and processes; 2) Understand the measurable attributes of objects and the units and methods of measurements; 3) Conduct data analysis (collecting, organizing, presenting scientific data, and to predict the result); 4) Use hands-on approaches to teach science; 5) Be familiar with Internet science teaching resources. Here we share our experiences and challenges we face while teaching this course.

Verner, E.; Bruhweiler, F. C.; Long, T.

2011-12-01

184

Combining Chemistry and Music to Engage Student Interest: Using Songs to Accompany Selected Chemical Topics  

ERIC Educational Resources Information Center

|The use of recorded music to add interest to a variety of lecture topics is described. Topics include the periodic table, the formation of ionic compounds, thermodynamics, carbohydrates, nuclear chemistry, and qualitative analysis. (Contains 1 note.)|

Last, Arthur M.

2009-01-01

185

Capture gamma-Ray Spectroscopy and Related Topics, 1984. AIP Conference Proceedings No. 125.  

National Technical Information Service (NTIS)

The main topics discussed at the symposium were nuclear models and theory, photon-induced reactions, neutron-induced reactions, charged-particle-induced reactions, applications, including nucleosynthesis, and related topics. Separate entries were prepared...

S. Raman

1985-01-01

186

Cutaneous Irritation in the Topical Application of Guanazole NSC-1895 to New Zealand White Rabbits.  

National Technical Information Service (NTIS)

The skin irritation potential of topically applied Guanazole NSC-1895 on New Zealand white rabbits was evaluated utilizing the method of Draize. Histologic studies of selected tissues including skin test sites were performed. Topically applied Guanazole a...

J. C. Murphy P. Skierkowski E. S. Watson R. M. Folk C. L. Litterst

1977-01-01

187

Cutaneous Irritation in the Topical Application of Azaserine NSC-742 to New Zealand White Rabbits.  

National Technical Information Service (NTIS)

The skin irritation potential of topically applied Azaserine NSC-742 on New Zealand white rabbits was evaluated utilizing the method of Draize. Histologic studies of selected tissues including skin test sites were performed. Topically applied Azaserine at...

J. C. Murphy P. Skierkowski E. S. Watson R. M. Folk C. L. Litterst

1977-01-01

188

Knowledge of the Future: Future Fables  

Microsoft Academic Search

Derrida's lecture “No Apocalypse, Not Now (Full Speed Ahead, Seven Missiles, Seven Missives)” is linked here to his discussions of 9\\/11, which share a concern with fables of the future, fictions or fables that condition the political and economic life of the present. This article is a reflection on futurity and the event, including the possibility of the destruction of

Richard Klein

2008-01-01

189

Topics in the physics and astrophysics of neutron stars  

NASA Astrophysics Data System (ADS)

In this dissertation, four topics related to the physics and astrophysics of neutron stars are studied. Two first topics deal with microscopical physics processes in the star outer crust and the last two with macroscopical properties of a star, such as mass and radius. In the first topic, the thermodynamical and transport properties of a dilute gas in which particles interact through a delta-shell potential are investigated. Through variations of a single parameter related to the strength and size of the delta-shell potential, the scattering length and effective range that determine the low-energy elastic scattering cross sections can be varied over wide ranges including the case of the unitary limit (infinite scattering length). It is found that the coefficients of shear viscosity, thermal conductivity and diffusion all decrease when the scattering length becomes very large and also when resonances occur as the temperature is increased. The calculated ratios of the shear viscosity to entropy density as a function of temperature for various interaction strengths (and therefore scattering lengths) were found to lie well above the recently suggested minimal value of (4pi)-1h/kB. A new result is the value of (4/5) for the dimensionless ratio of the energy density times the diffusion coefficient to viscosity for a dilute gas in the unitary limit. Whether or not this ratio changes upon the inclusion of more than two-body interactions is an interesting avenue for future investigations. These investigations shed pedagogical light on the issue of the thermal and transport properties of an interacting system in the unitary limit, of much current interest in both atomic physics and nuclear physics in which very long scattering lengths feature prominently at very low energies. In the second topic, the shear viscosity of a Yukawa liquid, a model for the outer crust of a neutron star, is calculated in both the classical and quantum regimes. Results of semi-analytic calculations in both regimes are presented for various temperatures and densities, and compared with those of classical molecular dynamical simulations performed for the same system by collaborators from Indiana University. For heavy-ion plasmas, as energetically favored in the outer crust of a neutron star, excellent agreement was found between the results of semi-analytic calculations and those of molecular dynamical simulations. However, in the case of light-ion plasmas, substantial differences were found between the results of quantum and classical cases, which underscores the importance of incorporating quantum effects in molecular dynamical simulations, even in the dilute limit. In the third topic, first steps are taken to reconstruct the uncertain high-density nuclear equation of state from the measured masses and radii of several individual stars. Inherent errors of the measurements are incorporated into the analysis. A new inversion procedure of the Tolman-Oppenheimer-Volkov stellar structure equation is developed so that a model independent dense matter of equation can be derived from observations. Successful tests of the inversion procedure emphasize the need to determine the masses and especially the radii of several individual stars. The aim here is to provide a benchmark equation of state for theoretical advances to be made. The fourth topic is concerned with the emerging field of gravitational-wave detections and its ability to shed light on the dense matter equation of state. In an external tidal gravitational field, as for example in binary star configurations, each star deforms and acquires a quadrupole moment. The quadrupole polarizability given by the coefficient of proportionality between the induced moment and the field called the tidal Love number after the English mathematician Love. By calculating Love numbers for several model equations of state, connections between the underlying equation of state, star structure and the tidal Love numbers of normal neutron stars and self-bound strange quark matter stars are established. It is shown that the meas

Postnikov, Sergey

190

Webwise 2010: Imagining the Digital Future  

NSDL National Science Digital Library

"Libraries and Museums in the Digital World" was the topic of the Webwise 2010 Conference in Denver, CO. The proceedings were faithfully recorded and offered as a webcast so that visitors who could not attend could still listen to all the lectures and discussions. Some of the topics that were covered at the conference include "interoperability, the future of collaboration, standards & best practices, technology and systems development, [and] training a 21st century cultural heritage information workforce." Visitors will find the webcast archive is at the bottom of the homepage, and it is divided up into "Pre-Conference #1", "Webwise 2010 - Day 1", and "Webwise 2010 - Day 2". Some of the Pre-Conference panels are "Digital Resources for Learning Spaces" and "21st Century Learners". "Webwise 2010 - Day 2" offers a lecture on the further education of librarians and information specialists, with "Skills for the Future: Educational Opportunities for Library and Museum". There's a great deal of material here for information technology specialists, librarians, and others.

2010-06-03

191

Eruptions of Mount St. Helens: Past, Present, and Future  

NSDL National Science Digital Library

This on-line book, published by the United States Geological Survey (USGS), covers the 1980 eruption of Mount St. Helens in Washington state. There is a discussion of the events leading up to the eruption, as well as an explanation of the mountain's volcanic history. Immediate effects are covered, including the ash falls, pyroclastic flows, and debris. Post-eruption topics include subsequent activity after the May 18th blast, comparison with other volcanoes, and possible future behavior. Additional reading resources are given for further reference.

Tilling, Robert; Swanson, Donald

192

The Future of Career.  

ERIC Educational Resources Information Center

|This book presents many views of the concept of "career," reviewing its past and considering its future in an international context including viewpoints from sociology, psychology, and human resources management. Following an introduction, "Framing the Future of Career" (Richard Young and Audrey Collin), the book contains the following 17…

Collin, Audrey, Ed.; Young, Richard A., Ed.

193

Topics and Sources of Memorable Breast Cancer Messages and Their Impact on Prevention and Detection Behaviors  

Microsoft Academic Search

Often, people are able to recall a message on a particular topic for a long period of time. These memorable messages have the ability to influence behavior when they are recalled from memory long after initial exposure. Knowing the topics and sources of the messages that are remembered about breast cancer can improve the efficacy of future breast cancer outreach.

Sandi W. Smith; Samantha Nazione; Carolyn LaPlante; Michael R. Kotowski; Charles Atkin; Christine M. Skubisz; Cynthia Stohl

2009-01-01

194

Application of XML Topic Maps to knowledge navigation and information retrieval for urban traffic information portal  

Microsoft Academic Search

Along with stocks of traffic information grows rapidly, knowledge navigation is the future development trend for managing urban traffic information resource. Topic Maps (TM) are standardized by ISO 13250 for the purpose of semantic annotation of WWW resources. XML Topic Maps (XTM) is straightforwardly usable over the Internet and support a wide variety of applications. This paper presents the knowledge

Zhai Jun; Wang Qinglian; Lv Miao

2008-01-01

195

Topics in elementary particle physics  

NASA Astrophysics Data System (ADS)

The author of this thesis discusses two topics in elementary particle physics: n-ary algebras and their applications to M-theory (Part I), and functional evolution and Renormalization Group flows (Part II). In part I, Lie algebra is extended to four different n-ary algebraic structure: generalized Lie algebra, Filippov algebra, Nambu algebra and Nambu-Poisson tensor; though there are still many other n-ary algebras. A natural property of Generalized Lie algebras — the Bremner identity, is studied, and proved with a totally different method from its original version. We extend Bremner identity to n-bracket cases, where n is an arbitrary odd integer. Filippov algebras do not focus on associativity, and are defined by the Fundamental identity. We add associativity to Filippov algebras, and give examples of how to construct Filippov algebras from su(2), bosonic oscillator, Virasoro algebra. We try to include fermionic charges into the ternary Virasoro-Witt algebra, but the attempt fails because fermionic charges keep generating new charges that make the algebra not closed. We also study the Bremner identity restriction on Nambu algebras and Nambu-Poisson tensors. So far, the only example 3-algebra being used in physics is the BLG model with 3-algebra A4, describing two M2-branes interactions. Its extension with Nambu algebra, BLG-NB model, is believed to describe infinite M2-branes condensation. Also, there is another propose for M2-brane interactions, the ABJM model, which is constructed by ordinary Lie algebra. We compare the symmetry properties between them, and discuss the possible approaches to include these three models into a grand unification theory. In Part II, we give an approximate solution for Schroeder's equations, based on series and conjugation methods. We use the logistic map as an example, and demonstrate that this approximate solution converges to known analytical solutions around the fixed point, around which the approximate solution is constructed. Although the closed-form solutions for Schroeder's equations can not always be approached analytically, by fitting the approximation solutions, one can still obtain closed-form solutions sometimes. Based on Schroeder's theory, approximate solutions for trajectories, velocities and potentials can also be constructed. The approximate solution is significantly useful to calculate the beta function in renormalization group trajectory. By "wrapping" the series solutions with the conjugations from different inverse functions, we generate different branches of the trajectory, and construct a counterexample for a folk theorem about limited cycles.

Jin, Xiang

196

Including Your Child  

NSDL National Science Digital Library

This publication, recently released by the US Department of Education, deal with special needs children and their parents. Including Your Child is a booklet for parents that deals with the first eight years of life for children with special needs. Its eight brief sections discuss the importance of the family, help and support systems, expectations, how to plan to meet expectations, inclusion, and outreach. It also contains a developmental progress chart and several sections of resource information.

197

Future directions for research on youth with bipolar spectrum disorders.  

PubMed

The past 25 years has witnessed significant advances in our knowledge of Bipolar Spectrum Disorders (BPSD) in youth. Cross-sectional and longitudinal studies are clarifying the unique features of its pediatric presentation, including continuities and discontinuities across the spectrum of severity. Advances have been made, both in the pharmacological and psychological management of BPSD in youth. Current investigations may ultimately shed light on new treatment strategies. Future research is anticipated to be influenced by NIMH's Research Domain Criteria (RDoC). With this article, we summarize what is currently known about the basic phenomenology of pediatric BPSD, its clinical course, assessment and treatment, beginning with a summary of the major studies that have shed light on the topic. Next, we present a tally and content review of current research as an indicator of trends for the future. Then, we describe what we believe are important future directions for research. Finally, we conclude with implications for contemporary clinicians and researchers. PMID:23915232

Fristad, Mary A; Algorta, Guillermo Perez

2013-08-05

198

Systemic Change: Touchstones for the Future School.  

ERIC Educational Resources Information Center

|Given the current social and economic changes, American education must change in order to connect students to the future. This book is comprised of a collection of essays on the topic of systemic change in education. The book focuses on reform for the future by bringing together systems theory with detailed examples of strategies and cases that…

Jenlink, Patrick, Ed.

199

Avoiding toxins including spermatotoxic medications.  

PubMed

Global rates of infertility are significant, especially in many developing countries. In developed countries, infertility affects up to 15% of the reproductive-age population, with male factors involved in 50% of cases. During medical evaluation, a review of current and past medications and social habits is essential, as they may adversely affect fertility. In addition, knowledge of exposure is important for counseling regarding future fertility, as many such toxic exposures have reversible effects. We reviewed the English literature over the past 35 years for all types of studies that have examined drug, medication, and other exposures that have been linked to altered semen quality and male fertility. Both human and animal studies were included in this analysis. The goal of this review is to delineate the medication and habitual risk factors that have been associated with male infertility. PMID:23775384

Stearns, Gillian; Turek, Paul J

2013-06-17

200

Topical Crawling for Business Intelligence  

Microsoft Academic Search

The Web provides us with a vast resource for business in- telligence. However, the large size of the Web and its dynamic nature make the task of foraging appropriate information challenging. General- purpose search engines and business portals may be used to gather some basic intelligence. Topical crawlers, driven by richer contexts, can then leverage on the basic intelligence to

Gautam Pant; Filippo Menczer

2003-01-01

201

Topic in Depth - Human Ectoparasites  

NSDL National Science Digital Library

If you were to worry about all of the parasites living on your body, often helping you, you'd never fall asleep. As a living organism part of a bigger ecosystem, humans play host to many other living things. This Topic In Depth offers a look into the fascinating world of Human Ectoparasites.

2010-09-03

202

Topics in Mitigating Radar Bias  

Microsoft Academic Search

In this paper, we investigate two topics related to mitigating the effect of radar bias in ballistic missile tracking applications. We determine the absolute bias between two radars in polar coordinates when their relative bias is given in rectangular coordinates. Using this result, we then obtain the optimized steady-state filter to handle the random bias.

Demetrios Serakos; John E. Gray; Hazim Youssef

2008-01-01

203

The Health Curriculum: 500 Topics.  

ERIC Educational Resources Information Center

|This 1958 paper divides 500 health topics into 20 categories: health as a social accomplishment/social problem; nutrition; physical fitness; mental health and disease; heredity/eugenics; infection/immunity; chronic and degenerative disease; substance abuse; skin care; vision, hearing, and speech; dental health; safety; physical environment;…

Byrd, Oliver E.

2001-01-01

204

Topics in Biomedical Optics: Introduction  

NASA Astrophysics Data System (ADS)

The field of biomedical optics is experiencing tremendous growth. Biomedical technologies contribute in the creation of devices used in healthcare of various specialties (ophthalmology, cardiology, anesthesiology, and immunology, etc.). Recent research in biomedical optics is discussed. Overviews of meetings held at the 2002 Optical Society of America Biomedical Topical Meetings are presented.

Hebden, Jeremy C.; Boas, David A.; George, John S.; Durkin, Anthony J.

2003-06-01

205

Topic in Depth - Animal Reproduction  

NSDL National Science Digital Library

This Topic in Depth takes a look at organizations and educational websites concerned with reproduction in humans and other animals. In this folder, you'll find information about fertility, embryology, reproductive biology, and immunology from a variety of societies and institutions.

2010-09-14

206

Seven topics in perturbative QCD  

SciTech Connect

The following topics of perturbative QCD are discussed: (1) deep inelastic scattering; (2) higher order corrections to e/sup +/e/sup -/ annihilation, to photon structure functions and to quarkonia decays; (3) higher order corrections to fragmentation functions and to various semi-inclusive processes; (4) higher twist contributions; (5) exclusive processes; (6) transverse momentum effects; (7) jet and photon physics.

Buras, A.J.

1980-09-01

207

RESEARCH TOPICS IN GAME THEORY  

Microsoft Academic Search

Research topics in game theory will cover the study of dynamic games, games of incomplete information, and evolutionary games, with applications in the fields of voting, bargaining, lobbying and violent conflict. Results from the study of social choice theory and mechanism design will also be treated. The course will concentrate on mathematical techniques for constructing and solving games. Students will

Macartan Humphreys

2004-01-01

208

Topics in Black Hole Evaporation  

Microsoft Academic Search

Two major aspects of particle creation by gravitational fields of black holes are studied: the neutrino emission from rotating black holes; and interactions between scalar particles emitted by a black hole. The neutrino emission is investigated under three topics. The asymmetry of the angular dependence of neutrino emission from rotating black holes is calculated first. A low frequency analytic approximation

Denis Alan Leahy

1980-01-01

209

Topics in optics and music  

NASA Astrophysics Data System (ADS)

While the use of optics in the playback of music has been a tremendously successful technology and laser light shows are a common occurrence, other intersections of optics and music tend to be less well known. Topics such as optics-based instruments, performance tools and effects, instrument characterization and manufacturing, recording, playback, and signal processing are explored.

Sparks, Andrew W.

2012-10-01

210

Ocular Safety of Topical Naltrexone.  

National Technical Information Service (NTIS)

Dr. Sassani and his associates have been funded to perform a Phase I Clinical Trial of Naltrexone dissolved in Vigamox (R) and applied topically as eye drops preliminary to a therapeutic trial of that medication in the treatment of corneal epithelial defe...

J. W. Sassani

2010-01-01

211

Some topics in Quantum Imaging  

Microsoft Academic Search

The field of Quantum Imaging exploits the quantum nature of light and the intrinsic parallelism of optical signals to devise novel techniques for optical imaging and for parallel information processing at the quantum level (see [1] and references quoted therein). In this presentation, we will shortly discuss two topics in this area: the first is the so-called ghost imaging which,

L. A. Lugiato; A. Gatti; E. Brambilla; L. Caspani; P. Di Trapani; O. Jedrkiewicz; F. Ferri; D. Magatti

2010-01-01

212

Benchmark Dose Modeling - Advanced Topics  

EPA Science Inventory

Benchmark Dose Modeling – Advanced Topics Course The objectives of this full-day course are to provide participants with training on how to use the U.S. Environmental Protection Agency’s (EPA) Benchmark Dose Modeling Software (BMDS) and related software programs to fa...

213

Future Developments!  

ERIC Educational Resources Information Center

|Six papers on future developments in computer-assisted learning (CAL) focus on the impact of computers on the future of education, use of path algebras for network analysis, impact of "programing literacy" on courseware, microcomputers as classroom teaching aids, Prestel for preschool education in the home, and courseware development and…

Rogers, David F., Ed.; Smith, P. R., Ed.

1984-01-01

214

Safe and effective application of topical treatments to the skin.  

PubMed

Skin conditions are common in all age ranges, and can significantly affect an individual's quality of life. Nurses prescribing or applying topical treatments should have a comprehensive understanding of skin barrier function and the effects this has on the absorption of medication through the skin. This article focuses on the therapeutic options available to treat skin conditions with particular emphasis on topical treatments, including emollients and topical corticosteroids. The principles of skin barrier function and the way in which therapies applied to the skin work are also discussed. PMID:23930532

Lawton, Sandra

215

An Effective Algorithm of News Topic Tracking  

Microsoft Academic Search

Topic tracking is to track trend of news topic, which people are interested in. It is a very pragmatic method in information retrieval. Compared with keywords retrieval, topic tracking excels in dynamic tracking based on text model and its content understanding, so it is mostly involved in text expressing and semantic understanding. LS-SVM, as a new method for news topic

Xianfei Zhang; Zhigang Guo; Bicheng Li

2009-01-01

216

Topic Structure Representation and Text Recall.  

ERIC Educational Resources Information Center

|College subjects were required to read and recall an expository text. They recalled information about fewer topics if they were randomly ordered and the introductory paragraph was uninformative. Subjects recalled information about more topics if the text contained topic sentences. Readers used representation of a text's topic structure to guide…

Lorch, Robert F., Jr.; Lorch, Elizabeth Pugzles

1985-01-01

217

Probabilistic Topic Models for Learning Terminological Ontologies  

Microsoft Academic Search

Probabilistic topic models were originally developed and utilized for document modeling and topic extraction in Information Retrieval. In this paper, we describe a new approach for automatic learning of terminological ontologies from text corpus based on such models. In our approach, topic models are used as efficient dimension reduction techniques, which are able to capture semantic relationships between word-topic and

Wang Wei; Payam Mamaani Barnaghi; Andrzej Bargiela

2010-01-01

218

Toward Theme Development Analysis with Topic Clustering  

Microsoft Academic Search

Topic summarization and analysis is very important to understand an academic document collection and is very paramount for scientific research, which can help researchers find the hot field. Many scholars used the topic model to analyze the theme development, such as LDA. However, these methods need a pre-specified number of latent topics and manual topic labeling, which is usually difficult

Xueyu Geng; Jinlong Wang

2008-01-01

219

Incorporating Women and Crime Topics into Criminology Classes: Assignments, Exercises, and Projects.  

ERIC Educational Resources Information Center

|Recommends a variety of books, assignments, exercises, and projects which can be incorporated into introductory criminology classes to compensate for the omission of topics on women and crime in textbooks and curricula. Includes a list of potential topics for writing assignments and a selection of films covering such topics as sexual harassment,…

Wright, Richard A.

1987-01-01

220

A Content Analysis of Lesbian, Gay, Bisexual, and Transgender Topics in Multicultural Education Textbooks  

ERIC Educational Resources Information Center

|This research examines the treatment of lesbian, gay, bisexual, and transgender (LGBT) topics in 12 popular multicultural education textbooks. Following a line-by-line analysis of each textbook, the findings report the extent to which LGBT topics were included in each text and the themes that became apparent in how LGBT topics were treated. The…

Jennings, Todd; Macgillivray, Ian K.

2011-01-01

221

Incorporating Women and Crime Topics into Criminology Classes: Assignments, Exercises, and Projects.  

ERIC Educational Resources Information Center

Recommends a variety of books, assignments, exercises, and projects which can be incorporated into introductory criminology classes to compensate for the omission of topics on women and crime in textbooks and curricula. Includes a list of potential topics for writing assignments and a selection of films covering such topics as sexual harassment,…

Wright, Richard A.

1987-01-01

222

High Priority Future Research Needs for Obstructive Sleep Apnea Diagnosis and Treatment  

PubMed Central

Study Objectives: To identify and prioritize future research needs (FRN) topics for diagnosis and treatment of obstructive sleep apnea (OSA). Methods: Twenty-one panel members represented six stake-holder categories: patients and the public, providers; purchasers of health care, payers, policymakers, and principal investigators. Building on a recently completed comparative effectiveness review, stakeholders nominated and discussed potential FRN topics. Stakeholders then nominated their top priority FRN topics based on the Agency for Healthcare Research and Quality Effective Health Care Program Selection Criteria. From these nominations, the highest priority FRN topics were determined and were elaborated upon to include possible study designs to address the topics. Results: Thirty-seven topics were discussed and prioritized. The nine highest priority FRN topics included: cost-effectiveness of management strategies, defining age- and sex-specific criteria for OSA, evaluating routine preoperative screening for OSA, evaluating involvement of a sleep medicine specialist in diagnosis of OSA, evaluating clinical prediction rules, assessing the effect of treating sleep disordered breathing and long-term clinical outcomes, comparing treatments for patients who do not tolerate positive airway pressure, evaluating strategies to improve treatment compliance, and evaluating the association between sleep apnea severity and long-term clinical outcomes. Conclusions: While there are numerous specific research questions with low or insufficient strength of evidence for OSA management, OSA patients, their healthcare providers, and society at large would benefit from refocusing research efforts into the prioritized research questions and away from simple comparisons of short-term outcomes between specific interventions. Citation: Patel K; Moorthy D; Chan JA; Concannon TW. High priority future research needs for obstructive sleep apnea diagnosis and treatment. J Clin Sleep Med 2013;9(4):395-402.

Patel, Kamal; Moorthy, Denish; Chan, Jeffrey A.; Concannon, Thomas W.; Ratichek, Sara J.; Chung, Mei; Balk, Ethan M.

2013-01-01

223

Topic Classification in Social Media Using Metadata from Hyperlinked Objects  

Microsoft Academic Search

\\u000a Social media presents unique challenges for topic classification, including the brevity of posts, the informal nature of conversations,\\u000a and the frequent reliance on external hyperlinks to give context to a conversation. In this paper we investigate the usefulness\\u000a of these external hyperlinks for determining the topic of an individual post. We focus specifically on hyperlinks to objects\\u000a which have related

Sheila Kinsella; Alexandre Passant; John G. Breslin

2011-01-01

224

(1) Detailed course description including topics to be discussed in the course  

Microsoft Academic Search

This course aims to provide a rigorous and critical introduction to Chinese historical lexicology, with emphasis on its theoretical aspect. It covers lexical semantics, meaning of word, development and evolution of Chinese lexical items over history, relationship between the sound and meaning, and the lexical system in ancient Chinese. The course also studies the vocabulary items in ancient script in

Jingtao SUN

225

TOPICAL REVIEW: Nucleosynthesis in classical nova explosions  

NASA Astrophysics Data System (ADS)

Classical novae are fascinating stellar explosions at the crossroads of stellar astrophysics, nuclear physics, and cosmochemistry. In this review, we briefly summarize 30 years of nucleosynthesis studies, with special emphasis on recent advances in nova theory (including multidimensional models) as well as on experimental efforts to reduce nuclear uncertainties affecting critical reaction rates. Among the topics that are covered, we outline the interplay between nova outbursts and the galactic chemical abundances, the synthesis of radioactive nuclei of interest for ?-ray astronomy, such as 7Li, 22Na or 26Al, and the potential discovery of presolar meteoritic grains likely condensed in nova shells.

José, Jordi; Hernanz, Margarita

2007-12-01

226

Do scientists trace hot topics?  

NASA Astrophysics Data System (ADS)

Do scientists follow hot topics in their scientific investigations? In this paper, by performing analysis to papers published in the American Physical Society (APS) Physical Review journals, it is found that papers are more likely to be attracted by hot fields, where the hotness of a field is measured by the number of papers belonging to the field. This indicates that scientists generally do follow hot topics. However, there are qualitative differences among scientists from various countries, among research works regarding different number of authors, different number of affiliations and different number of references. These observations could be valuable for policy makers when deciding research funding and also for individual researchers when searching for scientific projects.

Wei, Tian; Li, Menghui; Wu, Chensheng; Yan, Xiao-Yong; Fan, Ying; di, Zengru; Wu, Jinshan

2013-07-01

227

Preface to Special Topic: Optofluidics  

PubMed Central

This Special Topic section of Biomicrofluidics is on optofluidics or micro-optofluidic systems (MOFS), a burgeoning technology that aims to manipulate light and fluid at microscale and exploits their interaction to create highly versatile devices and integrated systems. This special issue puts together various contributed articles focusing on optofluidics or MOFS, which help inspire new research ideas and innovation in the microfluidics and nanofluidics community.

Liu, Ai-Qun

2010-01-01

228

Topical Ocular Delivery of NSAIDs  

Microsoft Academic Search

In ocular tissue, arachidonic acid is metabolized by cyclooxygenase to prostaglandins which are the most important lipid derived\\u000a mediators of inflammation. Presently nonsteroidal anti-inflammatory drugs (NSAIDs) which are cyclooxygenase (COX) inhibitors\\u000a are being used for the treatment of inflammatory disorders. NSAIDs used in ophthalmology, topically, are salicylic-, indole\\u000a acetic-, aryl acetic-, aryl propionic- and enolic acid derivatives. NSAIDs are weak

Munish Ahuja; Avinash S. Dhake; Surendra K. Sharma; Dipak K. Majumdar

2008-01-01

229

Topical Crawling for Business Intelligence  

Microsoft Academic Search

\\u000a The Web provides us with a vast resource for business intelligence. However, the large size of the Web and its dynamic nature\\u000a make the task of foraging appropriate information challenging. General-purpose search engines and business portals may be\\u000a used to gather some basic intelligence. Topical crawlers, driven by richer contexts, can then leverage on the basic intelligence\\u000a to facilitate in-depth

Gautam Pant; Filippo Menczer

230

4. Miscellaneous sports medicine topics  

Microsoft Academic Search

This self-directed learning module highlights new advances in this topic area. It is part of the chapter on musculoskeletal rehabilitation and sports medicine in the Self-Directed Physiatric Education Program for practitioners and trainees in physical medicine and rehabilitation. This article discusses physiatric duties as a team physician, preparticipation physical examinations, ergogenic aids, heat-related illness, pediatric sports injuries, female sports injuries,

Robert P. Wilder

1999-01-01

231

Major research topics in combustion  

Microsoft Academic Search

The Institute for Computer Applications in Science and Engineering (ICASE) and NASA Langley Research Center (LaRC) hosted a workshop on October 2--4, 1989 to discuss some combustion problems of technological interest to LaRC and to foster interaction with the academic community in these research areas. The topics chosen for this purpose were flame structure, flame holding\\/extinction, chemical kinetics, turbulence-kinetics interaction,

M. Y. Hussaini; A. Kumar; R. G. Voigt

1992-01-01

232

Topical Treatment of Cutaneous Leishmaniasis  

Microsoft Academic Search

Sixty-seven patients, 19 females and 48 males, 4-66 years old, suffering from lesions of cutaneous leishmaniasis were treated topically with an ointment comprising 15% paromomycin sulfate and 12% methylbenzethonium chloride in white soft paraffin (P-ointment, U.K. patent GB117237A). After 10 days of treatment, twice daily, the lesions in 72% of the treated patients were free of parasites, 15% became free

Joseph El-On; Rita Livshin; Zvi Even-Paz; David Hamburger; Louis Weinrauch

1986-01-01

233

Topical amitriptyline in healthy volunteers  

Microsoft Academic Search

Background and Objectives: The antidepressant amitriptyline is used as an adjuvant in the treatment of a variety of chronic pain conditions. This drug interacts with many receptors and ion channels, such as Na+ channels. In a randomized, double-blinded, and placebo-controlled trial, we investigated whether amitriptyline also is capable of providing cutaneous analgesia when applied topically in 14 healthy volunteers.Methods: Amitriptyline

Peter Gerner; Grace Kao; Venkatesh Srinivasa; Sanjeet Narang; Ging Kuo Wang

2003-01-01

234

HPA-axis activity as a predictor of future disruptive behaviors in young adolescents  

Microsoft Academic Search

Low HPA-axis activity has been proposed as a risk factor for disruptive behaviors. However longitudinal data on this topic are practically lacking. In the present study we investigated if low HPA-axis activity predicted future disruptive behaviors. We included 1,399 boys and girls from the Dutch general population, initially aged 10-12 years. At the first assessment, basal cortisol levels were assessed.

Frouke E. P. L. Sondeijker; Robert F. Ferdinand; Albertine J. Oldehinkel; Henning Tiemeier; Johan Ormel; FRANK C. VERHULSTa

2008-01-01

235

Future Professional Communication in Astronomy II  

NASA Astrophysics Data System (ADS)

The present volume gathers together the talks presented at the second colloquium on the Future Professional Communication in Astronomy (FPCAII), held at the Harvard-Smithsonian Center for Astrophysics (Cambridge, MA) on 13-14 April 2010. This meeting provided a forum for editors, publishers, scientists, librarians and officers of learned societies to discuss the future of the field. The program included talks from leading researchers and practitioners and drew a crowd of approximately 50 attendees from 10 countries. These proceedings contain contributions from invited and contributed talks from leaders in the field, touching on a number of topics. Among them: The role of disciplinary repositories such as ADS and arXiv in astronomy and the physical sciences; Current status and future of Open Access Publishing models and their impact on astronomy and astrophysics publishing; Emerging trends in scientific article publishing: semantic annotations, multimedia content, links to data products hosted by astrophysics archives; Novel approaches to the evaluation of facilities and projects based on bibliometric indicators; Impact of Government mandates, Privacy laws, and Intellectual Property Rights on the evolving digital publishing environment in astronomy; Communicating astronomy to the public: the experience of the International Year of Astronomy 2009.

Accomazzi, Alberto

236

Adult seborrheic dermatitis: a status report on practical topical management.  

PubMed

Seborrheic dermatitis is a common chronic-recurrent inflammatory disorder that most commonly affects adults; however, a more transient infantile form also occurs. The definitive cause of seborrheic dermatitis is unknown. However, proliferation of Malassezia species has been described as a contributing factor. The adult form of seborrheic dermatitis affects up to approximately five percent of the general population. The disorder commonly affects the scalp, face, and periauricular region, with the central chest, axillae, and genital region also involved in some cases. Pruritus is not always present and is relatively common, especially with scalp disease. A variety of treatments are available including topical corticosteroids, topical antifungal agents, topical calcineurin inhibitors, and more recently, a nonsteroidal "device "cream. This article reviews the practical topical management of seborrheic dermatitis in the United States, focusing on the adult population. PMID:21607192

Del Rosso, James Q

2011-05-01

237

Future Trends Program: Course Outline. (Appendix II, Futurizing the Power Industry.)  

ERIC Educational Resources Information Center

Consultants hired by a power company in the Central United States cooperated with employees to design a unique nine-month program called "Future Trends." The course, stressing the traits of man which enable him to adapt to the future, is outlined in this appendix. The course is divided into a preview and eight topic segments. A short description…

Harkins, Arthur M.; And Others

238

Radon programme: presence and future.  

PubMed

An overview of radon programme experience is presented. The paper summarises broad topics concerning radon issue: philosophy of radon policy, radon measurements strategies with respect to indoor radon variation, progress in radon measurement of an individual house (radon diagnosis), national programmes, the role of preventive measures and interventions with respect to existing and future exposure and knowledge of radon risk, problems of remediation strategies, radon mapping process and sense of delineation of radon prone areas, public awareness on radon issue and publicity campaign. Some research activities are proposed aiming at effective solutions for radon issues in the future. PMID:18420575

Hulka, J

2008-04-16

239

The Future of Poultry Welfare  

Microsoft Academic Search

\\u000a In contemplating the future of poultry welfare, one must be aware of the current situation in the context of how this issue\\u000a has evolved. From this perspective, one may project forward to identify opportunities for continued advancements and barriers\\u000a that must be negotiated. In this chapter, we will explore the development of poultry welfare as a topic of public concern

Suzanne T. Millman; Joy A. Mench; Anne E. Malleau

240

Energy future Santa Cruz. A citizens' plan for energy self-reliance  

SciTech Connect

The results of a grassroots energy conservation project which involved more than 3,100 residents of Santa Cruz, California, is discussed. Citizens attended forums and town meetings to suggest ideas for solving the community's energy problems. These ideas were then evaluated by the Energy Future Advisory Board and compiled into the Energy Future Plan. The energy plan covers such topics as new residences, residential retrofit, automobile efficiency, farm efficiency, commercial greenhouses, local food production, commercial efficiency, land use planning, energy education and financing, and solar, wind, and ocean energy. An energy implementation guide and glossary are included.

Cohn, J.; Stayton, R.

1982-01-01

241

Energy future Santa Cruz: A citizens' plan for energy self-reliance  

NASA Astrophysics Data System (ADS)

The results of a grassroots energy conservation project which involved more than 3,100 residents of Santa Cruz, California, is discussed. Citizens attended forums and town meetings to suggest ideas for solving the community's energy problems. These ideas were then evaluated by the Energy Future Advisory Board and compiled into the Energy Future Plan. The energy plan covers such topics as new residences, residential retrofit, automobile efficiency, farm efficiency, commercial greenhouses, local food production, commercial efficiency, land use planning, energy education and financing, and solar, wind, and ocean energy. An energy implementation guide and glossary are included.

Cohn, J.; Stayton, R.

242

Management of Research and Engineering Selected Topics.  

National Technical Information Service (NTIS)

This compendium discusses three topics of interest to managers of scientists and engineers. These three topics are development of scientists and engineers for technical management, performance appraisal of personnel, and means to effectiveness for project...

J. P. Hope

1976-01-01

243

Workplace Safety and Health Topics: Safety & Prevention  

MedlinePLUS

... About CDC.gov . NIOSH Home Workplace Safety & Health Topics NIOSH NIOSH A-Z Index What's New on ... New Archive 1996-1997 Workplace Safety and Health Topics Industries & Occupations Hazards & Exposures Diseases & Injuries Safety & Prevention ...

244

Environmental Health Topics from A to Z  

MedlinePLUS

... Education Home Page Brochures & Fact Sheets Environmental Health Topics Science Education Kids' Pages Research Home Page At ... for Scientists Clinical Research National Toxicology Program Research Topics Funding Opportunities Home Page Grants Challenge Awards Contracts & ...

245

Autism Spectrum Disorders (ASDs): Related Topics  

MedlinePLUS

... Ańadir en... Favorites Delicious Digg Google Bookmarks Related Topics Q: Do vaccines cause autism spectrum disorders (ASDs)? ... promote better use of research resources on vaccine topics. For more information about vaccines and ASDs, see: ...

246

Some topics in Quantum Imaging  

NASA Astrophysics Data System (ADS)

The field of Quantum Imaging exploits the quantum nature of light and the intrinsic parallelism of optical signals to devise novel techniques for optical imaging and for parallel information processing at the quantum level (see [1] and references quoted therein). In this presentation, we will shortly discuss two topics in this area: the first is the so-called ghost imaging which, however, is not necessarily quantum; the second is the detection of faint amplitude objects with a sensitivity beyond the standard quantum limit, and in this case we are fully in the quantum domain. Both topics are related to the phenomenon of optical parametric down-conversion (PDC), in which a fraction of the pump photons of a laser beam, injected into a crystal with a quadratic non-linearity, are down-converted to a pair of signal and idler photons, with conservation of total energy and total momentum. A feature of paramount importance is that the signal and idler beams are spatially correlated both in the near field (position correlation) and in the far field (momentum correlation).The simultaneous presence of position and momentum correlation implies quantum entanglement, as it has been also observed experimentally [2].

Lugiato, L. A.; Gatti, A.; Brambilla, E.; Caspani, L.; Di Trapani, P.; Jedrkiewicz, O.; Ferri, F.; Magatti, D.

2010-02-01

247

Language-Independent Informative Topic Segmentation  

Microsoft Academic Search

In this paper, we present an innovative topic segmentation system based on a new informative similarity measure that takes into account word co-occurrence in order to avoid the accessibility to existing linguistic resources such as electronic dictionaries or lexico-semantic databases such as thesauri or ontology. Topic Segmentation is the task of breaking documents into topically coherent multi-paragraph subparts. Topic Segmentation

GAËL DIAS

248

Hot Topic Detection in Professional Blogs  

Microsoft Academic Search

\\u000a Topics in professional blogs mainly refer to specific techniques. Today, professional blog websites have been important information\\u000a sources. However, information overload and the uncertainty of topic hotness evaluation have been obstacles for hot topic detection.\\u000a The paper proposes a method of detecting hot topics in professional blogs. The proposed method is based on the characteristics\\u000a of the professional blogs and

Erzhong Zhou; Ning Zhong; Yuefeng Li

249

Topic-based language models using EM  

Microsoft Academic Search

In this paper, we propose a novel statistical language model to capture topic-related long-range dependencies. Topics are mod- eled in a latent variable framework in which we also derive an EM algorithm to perform a topic factor decomposition based on a segmented training corpus. The topic model is combined with a standard language model to be used for on-line word

Daniel Gildea; Thomas Hofmann

1999-01-01

250

Topic Chains for Understanding a News Corpus  

Microsoft Academic Search

\\u000a The Web is a great resource and archive of news articles for the world. We present a framework, based on probabilistic topic\\u000a modeling, for uncovering the meaningful structure and trends of important topics and issues hidden within the news archives\\u000a on the Web. Central in the framework is a topic chain, a temporal organization of similar topics. We experimented with

Dongwoo Kim; Alice H. Oh

2011-01-01

251

Probabilistic Text Categorization using Sparse Topical Encoding  

Microsoft Academic Search

In this paper, we propose a topic-based probabilistic text categorization model, which can be decomposed into two steps. Firstly, we present sparse non-negative matrix factorization (SNMF) algo- rithm, which can extract the sparse topical encoding for documents automatically and has an intuitive interpretation. Secondly, we calculate the similarity between documents by integrating the probabilistic similarities of their topics, we can

Xipeng Qiuy; Xuanjing Huang; Lide Wu

252

Experimental Evidence for Preschoolers' Mastery of "Topic"  

ERIC Educational Resources Information Center

|This study investigates the acquisition of the discourse/pragmatic notion of topic, based on an experimental task eliciting topic vs. focus subjects. In spoken French, these are obligatorily realized as dislocated vs. nondislocated noun phrases. The results provide overwhelming evidence for the early mastery of topic, even by the youngest…

De Cat, Cecile

2009-01-01

253

Topic Structure Representation and Text Recall  

Microsoft Academic Search

It was hypothesized that readers represent a text's topics and their interrelations as they read, then use their representations to access information about each topic. In two experiments, college subjects were required to read and free recall an expository text. Experiment 1 manipulated both the order of topics in the stimulus text and whether or not the introductory paragraph stated

Robert F. Lorch; Elizabeth Pugzles Lorch

1985-01-01

254

Topical scar modification: hype or help?  

PubMed

Of the many topical scar modification treatments available, silicone gel sheeting is the only product shown to be effective for the treatment of hypertrophic scars. Other topical scar treatments are frequently used without evidence of their efficacy. The authors discuss available topical scar treatments and their current role in clinical plastic surgery practice. PMID:19338826

McGrath, Mary H; Chang, David S

255

Topical scar modification: Hype or help?  

Microsoft Academic Search

Of the many topical scar modification treatments available, silicone gel sheeting is the only product shown to be effective for the treatment of hypertrophic scars. Other topical scar treatments are frequently used without evidence of their efficacy. The authors discuss available topical scar treatments and their current role in clinical plastic surgery practice.

Mary H. McGrath; David S. Chang

2005-01-01

256

Novel topical therapies for distal colitis.  

PubMed

Distal colitis (DC) can be effectively treated with topical 5ASA agents. Suppositories target the rectum while enemas can reliably reach the splenic flexure. Used in combination with oral 5ASAs, the control of the inflammation is even more effective. Unfortunately, resistant DC does occur and can be extremely challenging to manage. In these patients, the use of steroids, immunosuppressants and the anti-tumor necrosis factor ? agents are often required. These, however, can be associated with systemic side effects and are not always effective. The investigation of new topical therapeutic agents is thus required as they are rarely associated with significant blood drug levels and side effects are infrequent. Some of the agents that have been proposed for use in resistant distal colitis include butyrate, cyclosporine and nicotine enemas as well as tacrolimus suppositories and tacrolimus, ecabet sodium, arsenic, lidocaine, rebamipide and Ridogrel(®) enemas. Some of these agents have demonstrated impressive results but the majority of the agents have only been assessed in small open-labelled patient cohorts. Further work is thus required with the investigation of promising agents in the context of randomized double-blinded placebo controlled trials. This review aims to highlight those potentially effective therapies in the management of resistant distal colitis and to promote interest in furthering their investigation. PMID:21577301

Lawrance, Ian Craig

2010-10-01

257

Topical 0.005% tacrolimus eye drop for refractory vernal keratoconjunctivitis  

Microsoft Academic Search

PurposeTo evaluate the efficacy and safety of topical 0.005% tacrolimus eye drop for treatment of refractory vernal keratoconjunctivitis (VKC).MethodsThis prospective study included 20 eyes of 10 patients with refractory VKC, who had active symptomatic disease despite conventional medications including topical steroids. After discontinuing all other medications, patients were treated with topical 0.005% tacrolimus eye drop four times a day. Changes

A Kheirkhah; M K Zavareh; F Farzbod; M Mahbod; M J Behrouz

2011-01-01

258

Topical agents for idiopathic distal colitis and proctitis.  

PubMed

Rectally administered topical agents have demonstrated efficacy in the maintenance of distal colitis (DC) and proctitis and as they are rarely associated with significant blood drug levels, side effects are infrequent. The topical 5-aminosalicylic acid (5-ASA) suppositories and enemas target different regions of the distal colon and are effective for proctitis and DC, respectively. They demonstrate clinical results that are better than oral 5-ASAs and are preferred to topical steroids with better clinical, endoscopic and histological outcomes, without the risk of adrenal suppression. Disease resistant to topical agents, however, can be extremely difficult to manage. The addition of oral 5ASAs, steroids, immunosuppressants and the anti-tumor necrosis factor-? agents may be effective, but can result in significant side effects and not all patients will respond to the therapies. It is for these patients that new and novel therapies are required. Novel topical agents have been proposed for the management of resistant DC. These agents included butyrate, cyclosporine, and nicotine enemas, as well as tacrolimus suppositories, and tacrolimus, ecabet sodium, arsenic, lidocaine, bismuth, rebamipide and thromboxane enemas. While some of these agents appear to demonstrate impressive outcomes, the majority have only been examined in small open-labeled studies. There is thus a desperate need for more randomized double-blinded placebo controlled studies to investigate the clinical utility of these topical therapies. This review summarizes the efficacy of the established topical therapies, and explores the available data on the new and novel topical agents for the management of DC and proctitis. PMID:21175791

Lawrance, Ian Craig

2011-01-01

259

Topical therapy for fungal infections.  

PubMed

Fungi often infect the skin surface and subsequently invade the stratum corneum to avoid being shed from the skin surface by desquamation. Pharmacologic agents applied to the surface of the skin in the form of creams, lotions, or sprays, readily penetrate into the stratum corneum to kill the fungi (fungicidal agents), or at least render them unable to grow or divide (fungistatic agents). Thus, topical therapies work well to rid the skin of topical fungi and yeasts. Azole drugs such as miconazole, clotrimazole, and ketoconazole are fungistatic, limiting fungal growth but depending on epidermal turnover to shed the still-living fungus from the skin surface. Allylamines and benzylamines such as terbinafine, naftifine, and butenafine are fungicidal, actually killing the fungal organisms. Fungicidal drugs are often preferred over fungistatic drugs for treatment of dermatophytic fungal infections, since treatment times as short as one application daily for 1 week are associated with high cure rates. Furthermore, patients often stop treatments when the skin appears healed, usually after about a week of treatment. If this short-term treatment is stopped, fungi recur more often when fungistatic, rather than fungicidal, drugs have been used. Yeast infections such as those caused by Candida albicans respond less well to allylamine drugs. The azole drugs are often preferred for these types of infections. Nail infections are difficult to cure with topical therapies because the infections usually occur under the nail instead of on top of it and products penetrate poorly, if at all, through the nail plate. Infections of hair follicles, nails, and widespread infections often require systemic treatments. Antifungal agents are compounded into many different types of vehicles. Patients often prefer to treat weeping infections with spray formulations. Most physicians prescribe branded products in cream or lotion bases. Cost is a factor dictating prescription choice, especially since most products work well regardless of mechanism of action. Cost becomes especially important when infections involve large areas of the body surface. This article reviews various treatments of cutaneous fungal infections, with special emphasis on cure rates and rationales for choosing particular products. PMID:15663341

Kyle, Amber A; Dahl, Mark V

2004-01-01

260

Cutaneous Irritation in the Topical Application of Methyl-GAG NSC-32946 to New Zealand White Rabbits.  

National Technical Information Service (NTIS)

The skin irritation potential of topically applied Methyl GAG NSC-32946 on New Zealand white rabbits was evaluated utilizing the method of Draize. Histologic studies of selected tissues including skin test sites were performed. Topically applied Methyl GA...

J. C. Murphy P. Skierkowski E. S. Watson R. M. Folk C. L. Litterst

1977-01-01

261

Topical Immunotherapy in Alopecia Areata  

PubMed Central

Alopecia Areata (AA) is a common non-scarring alopecia directed against the anagenic hair follicle. Various treatment modalities have been used for the treatment of severe AA. Topical immunotherapy is the best documented treatment so far for severe and refractory AA. Dinitrochlorobenzene (DNCB), squaric acid dibutylester (SADBE), and diphencyprone (DPCP) are the contact allergens used for this purpose. DNCB has been found to be mutagenic by the Ames test and is largely replaced by DPCP and SADBE. DPCP and SADBE are both known to be non-mutagenic compounds and have comparable efficacy results and relapse rates. SADBE requires special solvents and additives to maintain its potency and is more expensive than the rest. DPCP has a response rate varying from 60% in severe Alopecia Areata to 17% in patients with alopecia totalis or universalis, and shows about 88 to 100% high response rate in patients with patchy Alopecia Areata.

Singh, Gurcharan; Lavanya, MS

2010-01-01

262

Through the '80s: thinking globally, acting locally. [Combined Canadian Futures Society and Third General Assembly of World Future Society  

SciTech Connect

This volume was prepared in conjunction with the First Global Conference on the Future, held in Toronto, Canada, July 20-24, 1980. The conference combined the Third General Assembly of the World Future Society and the fifth annual conference of the Canadian Futures Society. The 59 papers presented here were selected from the very large number submitted to the conference committee; space limitations permitted only a small number of papers to be published in this volume. Included also are: the foreword, Mystery of the Future, by Edward R. Schreyer, Governor General of Canada; preface, A Time for Action, by Maurice F. Strong; introduction, Transition to Harmonic Globalism, by Frank Feather; conclusion, What We Must Do: An Agenda for Futurists; and postscript, The Challenge of the '80s, by Aurelio Peccei. The papers were presented under the following topics: The Trauma of Change (4); A Global Perspective (7); Inventorying Our Resources (7); The International Context (8); Economics: Getting Down to Business (9); Human Values: Personal, Social, Religious (6); Communications: Connecting Ourselves Together (4); Education: Learning to Meet Tomorrow (4); Health: New Approaches to Staying Fit (3); Futurism as a Way of Life (5); and Dreams into Action: Methods and Real-Life Experience (2).

Feather, F. (ed.)

1980-01-01

263

Biomedical applications reviewed: Hot topic areas  

NASA Astrophysics Data System (ADS)

Making reference to the British Journal of Radiology and competitor journal titles, we look at the general area of biomedical physics, reviewing some of the associated topics in ionising radiation research attracting interest over the past 2 years. We also reflect on early developments that have paved the way for these endeavours. The talk is illustrated by referring to a number of biomedical physics areas in which this group has been directly involved, including novel imaging techniques that address compositional and structural makeup as well as use of elastically scattered X-ray phase contrast, radiation damage linking to possible pericardial effects in radiotherapy, simulation of microvascularity and oxygenation with a focus of radiation resistant hypoxic tumours, issues of high spatial resolution dosimetry and tissue interface radiotherapy with doses enhanced through use of high atomic number photoelectron conversion media.

Bradley, D. A.; Wells, K.

2013-04-01

264

Preformulation, formulation, and in vivo efficacy of topically applied apomine.  

PubMed

Apomine is a novel compound that inhibits the mevalonate/isoprenoid pathway of cholesterol synthesis and may prove effective as a skin cancer chemoprevention therapy. This research was focused on the development of a new delivery approach for chemoprevention of melanoma using topically delivered apomine. This included evaluating the effect of several factors on the stability of apomine in solution, utilizing these to develop a topical formulation, and conducting efficacy studies with the developed topical formulation in the TPras mouse model. Preformulation included the influence of pH, buffer species, ionic strength, and organic solvents on the stability of apomine at four different temperatures. Apomine was determined to undergo apparent first-order degradation kinetics for all conditions evaluated. Apomine undergoes base-catalyzed degradation. Less than 15% degradation is observed after >200 days under acidic conditions. Long-term stability studies were performed on two different topical cream formulations and indicate that both formulations are chemically stable for over 1 year at both 4 and 23 degrees C. The efficacy of topically applied apomine, from ethanol and developed 1% cream, was evaluated in vivo against the incidence of melanoma. Regardless of delivery vehicle apomine treatment caused a significant reduction in tumor incidence. Ethyl alcohol application of apomine resulted in a greater tumor incidence reduction when compared to the development cream formulation; however, this difference was not significant. PMID:19699284

Kuehl, Philip J; Stratton, Steven P; Powell, Marianne B; Myrdal, Paul B

2009-08-20

265

Pathways to the Future: A Review of Military Family Research.  

National Technical Information Service (NTIS)

Each chapter in this compendium focuses on a particular topic area and reviews what we have learned, identifies gaps in our present knowledge, and suggests directions for future research on military members and their families. In several cases, theoretica...

P. McClure

1999-01-01

266

Shourai Gata Yusou Kei Ni Tsuite (Future Transportation Systems).  

National Technical Information Service (NTIS)

A study was made of fly-back boosters as one future space transportation system. After presenting premises for review such as launch date, launch site, system configurations, numbers of reuse, and system structure, the following topics were discussed: spe...

T. Etou

1991-01-01

267

Bibliography of subsidence and related topics for in situ coal gasification  

Microsoft Academic Search

The topics included are: (1) subsidence, (2) subsidence models, (3) material properties and in situ measurements, and (4) hydrology of fractured media. Each topic is indexed by year and then alphabetically by author within each year. Abstracts of each article were included when available; abstracts were usually composed in cases where a paper could be obtained but no abstract was

C. R. McKee; A. Serafini

1978-01-01

268

HierarchicalTopics: Visually Exploring Large Text Collections Using Topic Hierarchies.  

PubMed

Analyzing large textual collections has become increasingly challenging given the size of the data available and the rate that more data is being generated. Topic-based text summarization methods coupled with interactive visualizations have presented promising approaches to address the challenge of analyzing large text corpora. As the text corpora and vocabulary grow larger, more topics need to be generated in order to capture the meaningful latent themes and nuances in the corpora. However, it is difficult for most of current topic-based visualizations to represent large number of topics without being cluttered or illegible. To facilitate the representation and navigation of a large number of topics, we propose a visual analytics system - HierarchicalTopic (HT). HT integrates a computational algorithm, Topic Rose Tree, with an interactive visual interface. The Topic Rose Tree constructs a topic hierarchy based on a list of topics. The interactive visual interface is designed to present the topic content as well as temporal evolution of topics in a hierarchical fashion. User interactions are provided for users to make changes to the topic hierarchy based on their mental model of the topic space. To qualitatively evaluate HT, we present a case study that showcases how HierarchicalTopics aid expert users in making sense of a large number of topics and discovering interesting patterns of topic groups. We have also conducted a user study to quantitatively evaluate the effect of hierarchical topic structure. The study results reveal that the HT leads to faster identification of large number of relevant topics. We have also solicited user feedback during the experiments and incorporated some suggestions into the current version of HierarchicalTopics. PMID:24051766

Dou, Wenwen; Yu, Li; Wang, Xiaoyu; Ma, Zhiqiang; Ribarsky, William

2013-12-01

269

Future trends in terrorism  

Microsoft Academic Search

This article will explore the directions terrorism can be expected to take in the 21st century. The future of terrorism in the United States is examined and analyzed in terms of international, transnational, domestic, and state terrorist activities. General trends are also discussed, including nuclear, biological, and chemical terrorism. It is suggested that education of the public into the causes,

Wayman C. Mullins

1997-01-01

270

Technologies of the Future.  

ERIC Educational Resources Information Center

|In the future, the requirements of industry will generate a wide range of hardware devices and software programs that will significantly alter and improve the quality of education. The driving forces behind the development of new technological devices include economics; emotional factors, e.g., the desire to develop aids for the handicapped;…

Lipson, Joseph I.; Fisher, Kathleen M.

1985-01-01

271

EMLA®-induced methemoglobinemia and systemic topical anesthetic toxicity  

Microsoft Academic Search

This case report illustrates an adult presenting with the simultaneous occurrence of both methemoglobinemia (MetHb) and systemic toxicity from the topical application of local anesthetics while undergoing laser epilation therapy of the legs. The concurrent development of both is considered uncommon in this setting and may have been related to several factors, including her recent previous treatment, increased absorption secondary

In-Hei Hahn; Robert S Hoffman; Lewis S Nelson

2004-01-01

272

Composition and method for topical treatment of androgenic alopecia  

US Patent & Trademark Office Database

This invention relates to the topical and oral treatment of hair loss, especially androgenic alopecia, by providing formulations that include anti-androgens, especially extracts of the saw palmetto plant, co-enzyme Q, and acetyl carnitine, and optionally stimulators of adenylate cyclase to stimulate hair growth, to increase the luster of hair, and to decrease hair graying.

Crandall; Wilson T. (Ft. Defiance, VA)

2001-12-25

273

Future directions for QCD  

SciTech Connect

New directions for exploring QCD at future high-energy colliders are sketched. These include jets within jets. BFKL dynamics, soft and hard diffraction, searches for disoriented chiral condensate, and doing a better job on minimum bias physics. The new experimental opportunities include electron-ion collisions at HERA, a new collider detector at the C0 region of the TeVatron, and the FELIX initiative at the LHC.

Bjorken, J.D.

1996-10-01

274

"The Future of Secondary Science Education: Charting a Course for Renewal." Proceedings of the Alberta Science Education Leaders' Symposia (Calgary, Alberta, Canada, December 5, 1997) and (Edmonton, Alberta, Canada, March 13, 1998).  

ERIC Educational Resources Information Center

|This paper features a summary of comments and suggestions from participants in the Alberta Science Education Leaders' Symposia on the future of secondary science education. Topics discussed include needs, challenges, and concerns in science education; suggestions for change; renewing secondary science programs; professional development of…

Alberta Dept. of Education, Edmonton. Curriculum Standards Branch.

275

[Current topics in pediatric nutrition].  

PubMed

As main current topics in pediatric nutrition we have considered the results of the continuing research on the long term consequences of fetal malnutrition and intra-uterine growth retardation with the concept of metabolic imprinting leading to chronic disease in adulthood, the progresses of knowledge in the fields of iron metabolism and regulatory mechanisms of satiety, hunger and energetic balance, a better determination of recommended docosahexanoic and arachidonic acids intake in the first months of life for premature and term infants, and the studies on probiotics and prebiotics utilization for preventive and curative purposes. The concerns about vitamin D insufficiency in France have markedly decreased with the generalization ten years ago of cholecalciferol supplementation of infant formula, and more recently the authorization of dairy products supplementation. On the contrary the problem of iron deficiency in young children remains, as well as two major nutritional concerns: the very low percentage of breast-fed infants and the dramatic increase of childhood obesity which affects presently 14% of 10 year old children versus 5% in 1980. PMID:12162162

Morali, A; Vidailhet, M

2002-07-01

276

Method and system for indentifying significant topics of a document  

US Patent & Trademark Office Database

A "domain-general" method for representing the "sense" of a document includes the steps of extracting a list of simplex noun phrases representing candidate significant topics in the document, clustering the simplex noun phrases by head, and ranking the simplex noun phrases according to a significance measure to indicate the relative importance of the simplex noun phrases as significant topics of the document. Furthermore, the output can be filtered in a variety of ways, both for automatic processing and for presentation to users.

2000-12-26

277

Usage-Oriented Topic Maps Building Approach  

NASA Astrophysics Data System (ADS)

In this paper, we present a collaborative and incremental construction approach of multilingual Topic Maps based on enrichment and merging techniques. In recent years, several Topic Map building approaches have been proposed endowed with different characteristics. Generally, they are dedicated to particular data types like text, semi-structured data, relational data, etc. We note also that most of these approaches take as input monolingual documents to build the Topic Map. The problem is that the large majority of resources available today are written in various languages, and these resources could be relevant even to non-native speakers. Thus, our work is driven towards a collaborative and incremental method for Topic Map construction from textual documents available in different languages. To enrich the Topic Map, we take as input a domain thesaurus and we propose also to explore the Topic Map usage which means available potential questions related to the source documents.

Ellouze, Nebrasse; Lammari, Nadira; Métais, Elisabeth; Ben Ahmed, Mohamed

278

Identifying Health-Related Topics on Twitter  

NASA Astrophysics Data System (ADS)

Public health-related topics are difficult to identify in large conversational datasets like Twitter. This study examines how to model and discover public health topics and themes in tweets. Tobacco use is chosen as a test case to demonstrate the effectiveness of topic modeling via LDA across a large, representational dataset from the United States, as well as across a smaller subset that was seeded by tobacco-related queries. Topic modeling across the large dataset uncovers several public health-related topics, although tobacco is not detected by this method. However, topic modeling across the tobacco subset provides valuable insight about tobacco use in the United States. The methods used in this paper provide a possible toolset for public health researchers and practitioners to better understand public health problems through large datasets of conversational data.

Prier, Kyle W.; Smith, Matthew S.; Giraud-Carrier, Christophe; Hanson, Carl L.

279

Future Fab: International  

NSDL National Science Digital Library

Future Fab International offers a large selection of articles and white papers related to the semiconductor industry. With contributors from hundreds of companies and an editorial board comprised of IBM, Intel, and Texas Instruments representatives, it is a well respected publication. The last six volumes are currently online, with about 280 white papers listed. Articles deal with many aspects of fabrication, including wafer processing and contamination control. Major press releases are also given on the site. Future Fab is an annual publication, according to the Web site, but it appears to be released twice per year.

2002-01-01

280

Topic-based web site summarization  

Microsoft Academic Search

Purpose – Summarization of an entire web site with diverse content may lead to a summary heavily biased towards the site's dominant topics. The purpose of this paper is to present a novel topic-based framework to address this problem. Design\\/methodology\\/approach – A two-stage framework is proposed. The first stage identifies the main topics covered in a web site via clustering

Yongzheng Zhang; Evangelos E. Milios; A. Nur Zincir-Heywood

2010-01-01

281

Tracking topic birth and death in LDA.  

SciTech Connect

Most topic modeling algorithms that address the evolution of documents over time use the same number of topics at all times. This obscures the common occurrence in the data where new subjects arise and old ones diminish or disappear entirely. We propose an algorithm to model the birth and death of topics within an LDA-like framework. The user selects an initial number of topics, after which new topics are created and retired without further supervision. Our approach also accommodates many of the acceleration and parallelization schemes developed in recent years for standard LDA. In recent years, topic modeling algorithms such as latent semantic analysis (LSA)[17], latent Dirichlet allocation (LDA)[10] and their descendants have offered a powerful way to explore and interrogate corpora far too large for any human to grasp without assistance. Using such algorithms we are able to search for similar documents, model and track the volume of topics over time, search for correlated topics or model them with a hierarchy. Most of these algorithms are intended for use with static corpora where the number of documents and the size of the vocabulary are known in advance. Moreover, almost all current topic modeling algorithms fix the number of topics as one of the input parameters and keep it fixed across the entire corpus. While this is appropriate for static corpora, it becomes a serious handicap when analyzing time-varying data sets where topics come and go as a matter of course. This is doubly true for online algorithms that may not have the option of revising earlier results in light of new data. To be sure, these algorithms will account for changing data one way or another, but without the ability to adapt to structural changes such as entirely new topics they may do so in counterintuitive ways.

Wilson, Andrew T.; Robinson, David Gerald

2011-09-01

282

Evaluative Conditioning: Recent Developments and Future Directions  

ERIC Educational Resources Information Center

Evaluative conditioning (EC) is generally considered to be one of the routes via which likes and dislikes are acquired. We identify recent trends in EC research and speculate about the topics that will dominate future research on EC. Many of the recent developments in EC research were shaped by functional definitions of EC that refer only to…

Gast, Anne; Gawronski, Bertram; De Houwer, Jan

2012-01-01

283

Evaluative Conditioning: Recent Developments and Future Directions  

ERIC Educational Resources Information Center

|Evaluative conditioning (EC) is generally considered to be one of the routes via which likes and dislikes are acquired. We identify recent trends in EC research and speculate about the topics that will dominate future research on EC. Many of the recent developments in EC research were shaped by functional definitions of EC that refer only to…

Gast, Anne; Gawronski, Bertram; De Houwer, Jan

2012-01-01

284

People, Law, and the Futures Perspective.  

ERIC Educational Resources Information Center

|The technology being developed today will create an extensive array of new legal problems for the citizens of the future. This booklet outlines a study unit designed to introduce today's students to these problems and to the factors that will have to be considered in their solution. The course is organized around five topics: the changing nature…

Franks, Betty Barclay; Howard, Mary Kay

285

Including All Learners: QCA's Approach.  

ERIC Educational Resources Information Center

The Principal Manager for Equal Opportunities and Access of the British Qualifications and Curriculum Authority (QCA) outlines recent and future developments initiated by the QCA concerning inclusion of students with special educational needs. Discussion focuses on general principles of the QCA, the National Curriculum, "target setting" for pupils…

Wade, Judith

1999-01-01

286

Topical Prophylaxis for HIV Prevention in Women: Becoming a Reality  

PubMed Central

Strategies to protect against sexual transmission of HIV include the development of products formulated for topical application, which limit the toxicities associated with systemic oral pre-exposure prophylaxis. Following several clinical trial failures, attention is now focused on antiretroviral (ARV) agents. Highly potent ARV topical formulations provide a female-controlled, targeted, and feasible option for HIV prevention. A recently completed tenofovir gel trial was the first to demonstrate significant protection against HIV acquisition. Topical ARVs have the advantage of delivering high concentration of drug at the site of transmission of HIV, with low systemic absorption. Sustained-release formulations, such as intravaginal rings, will likely improve adherence and can be designed to provide controlled and continuous delivery of ARV combinations. Further studies to test alternative dosing strategies and pharmacokinetic/pharmacodynamic relationships in the genital tract will provide valuable information as the field strives to improve upon the promising tenofovir gel trial results.

Verma, Natasha A.; Lee, Anna C.; Herold, Betsy C.

2011-01-01

287

Principles of office anesthesia: part II. Topical anesthesia.  

PubMed

The development of topical anesthetics has provided the family physician with multiple options in anesthetizing open and intact skin. The combination of tetracaine, adrenaline (epinephrine), and cocaine, better known as TAC, was the first topical agent available for analgesia of lacerations to the face and scalp. Cocaine has been replaced with lidocaine in a newer formulation called LET (lidocaine, epinephrine, and tetracaine). For analgesia to nonintact skin, LET gel is generally preferred over TAC because of its superior safety record and cost-effectiveness. EMLA (eutectic mixture of local anesthetics) is perhaps the most well-known topical anesthetic for use on intact skin. EMLA can be used to anesthetize the skin before intramuscular injections, venipuncture, and simple skin procedures such as curettage or biopsy. To be fully effective, EMLA should be applied at least 90 minutes before the procedure. ELA-Max is a new, rapidly acting topical agent for intact skin that works by way of a liposomal delivery system and is available over the counter. Other delivery vehicles for topical anesthesia currently in development, including iontophoresis and anesthetic patches, may one day give patients and physicians even more flexibility. PMID:12126037

Kundu, Suriti; Achar, Suraj

2002-07-01

288

Spoken Document Retrieval Leveraging Unsupervised and Supervised Topic Modeling Techniques  

NASA Astrophysics Data System (ADS)

This paper describes the application of two attractive categories of topic modeling techniques to the problem of spoken document retrieval (SDR), viz. document topic model (DTM) and word topic model (WTM). Apart from using the conventional unsupervised training strategy, we explore a supervised training strategy for estimating these topic models, imagining a scenario that user query logs along with click-through information of relevant documents can be utilized to build an SDR system. This attempt has the potential to associate relevant documents with queries even if they do not share any of the query words, thereby improving on retrieval quality over the baseline system. Likewise, we also study a novel use of pseudo-supervised training to associate relevant documents with queries through a pseudo-feedback procedure. Moreover, in order to lessen SDR performance degradation caused by imperfect speech recognition, we investigate leveraging different levels of index features for topic modeling, including words, syllable-level units, and their combination. We provide a series of experiments conducted on the TDT (TDT-2 and TDT-3) Chinese SDR collections. The empirical results show that the methods deduced from our proposed modeling framework are very effective when compared with a few existing retrieval approaches.

Chen, Kuan-Yu; Wang, Hsin-Min; Chen, Berlin

289

TOPICAL REVIEW: The Verwey transition - a topical review  

NASA Astrophysics Data System (ADS)

This review encompasses the story of the Verwey transition in magnetite over a period of about 90 years, from its discovery up to the present. Despite this long period of thorough investigation, the intricate multi-particle system Fe3O4 with its various magneto-electronic interactions is not completely understood, as yet - although considerable progress has been achieved, especially during the last two decades. It therefore appeared appropriate to subdivide this retrospect into three eras: (I) from the detection of the effect to the Verwey model (1913-1947), being followed by a period of: (II) checking, questioning and modification of Verwey's original concepts (1947-1979). Owing to prevailing under-estimation of the role of crystal preparation and qualitiy control, this period is also characterized by a series of uncertainties and erroneous statements concerning the reaction order (one or two) and type of the transition (multi-stage or single stage). These latter problems, beyond others, could definitely be solved within era (III) (1979 to the present) - in favour of a first-order, single-stage transition near 125 K - on the basis of experimental and theoretical standards established in the course of a most inspiring conference organized in 1979 by Sir Nevill Mott in Cambridge and solely devoted to the present topic. Regarding the experimental field of further research, the remarkable efficiency of magnetic after-effect (MAE) spectroscopy as a sensitive probe for quality control and investigation of low-temperature (4 KTv) into a Wigner crystal (T

Walz, Friedrich

2002-04-01

290

Selected topics of fluid mechanics  

USGS Publications Warehouse

The fundamental equations of fluid mechanics are specific expressions of the principles of motion which are ascribed to Isaac Newton. Thus, the equations which form the framework of applied fluid mechanics or hydraulics are, in addition to the equation of continuity, the Newtonian equations of energy and momentum. These basic relationships are also the foundations of river hydraulics. The fundamental equations are developed in this report with sufficient rigor to support critical examinations of their applicability to most problems met by hydraulic engineers of the Water Resources Division of the United States Geological Survey. Physical concepts are emphasized, and mathematical procedures are the simplest consistent with the specific requirements of the derivations. In lieu of numerical examples, analogies, and alternative procedures, this treatment stresses a brief methodical exposition of the essential principles. An important objective of this report is to prepare the user to read the literature of the science. Thus, it begins With a basic vocabulary of technical symbols, terms, and concepts. Throughout, emphasis is placed on the language of modern fluid mechanics as it pertains to hydraulic engineering. The basic differential and integral equations of simple fluid motion are derived, and these equations are, in turn, used to describe the essential characteristics of hydrostatics and piezometry. The one-dimensional equations of continuity and motion are defined and are used to derive the general discharge equation. The flow net is described as a means of demonstrating significant characteristics of two-dimensional irrotational flow patterns. A typical flow net is examined in detail. The influence of fluid viscosity is described as an obstacle to the derivation of general, integral equations of motion. It is observed that the part played by viscosity is one which is usually dependent on experimental evaluation. It follows that the dimensionless ratios known as the Euler, Froude, Reynolds, Weber, and Cauchy numbers are defined as essential tools for interpreting and using experimental data. The derivations of the energy and momentum equations are treated in detail. One-dimensional equations for steady nonuniform flow are developed, and the restrictions applicable to the equations are emphasized. Conditions of uniform and gradually varied flow are discussed, and the origin of the Chezy equation is examined in relation to both the energy and the momentum equations. The inadequacy of all uniform-flow equations as a means of describing gradually varied flow is explained. Thus, one of the definitive problems of river hydraulics is analyzed in the light of present knowledge. This report is the outgrowth of a series of short schools conducted during the spring and summer of 1953 for engineers of the Surface Water Branch, Water Resources Division, U. S. Geological Survey. The topics considered are essentially the same as the topics selected for inclusion in the schools. However, in order that they might serve better as a guide and outline for informal study, the arrangement of the writer's original lecture notes has been considerably altered. The purpose of the report, like the purpose of the schools which inspired it, is to build a simple but strong framework of the fundamentals of fluid mechanics. It is believed that this framework is capable of supporting a detailed analysis of most of the practical problems met by the engineers of the Geological Survey. It is hoped that the least accomplishment of this work will be to inspire the reader with the confidence and desire to read more of the recent and current technical literature of modern fluid mechanics.

Kindsvater, Carl E.

1958-01-01

291

Topical ocular delivery of NSAIDs.  

PubMed

In ocular tissue, arachidonic acid is metabolized by cyclooxygenase to prostaglandins which are the most important lipid derived mediators of inflammation. Presently nonsteroidal anti-inflammatory drugs (NSAIDs) which are cyclooxygenase (COX) inhibitors are being used for the treatment of inflammatory disorders. NSAIDs used in ophthalmology, topically, are salicylic-, indole acetic-, aryl acetic-, aryl propionic- and enolic acid derivatives. NSAIDs are weak acids with pKa mostly between 3.5 and 4.5, and are poorly soluble in water. Aqueous ophthalmic solutions of NSAIDs have been made using sodium, potassium, tromethamine and lysine salts or complexing with cyclodextrins/solubilizer. Ocular penetration of NSAID demands an acidic ophthalmic solution where cyclodextrin could prevent precipitation of drug and minimize its ocular irritation potential. The incompatibility of NSAID with benzalkonium chloride is avoided by using polysorbate 80, cyclodextrins or tromethamine. Lysine salts and alpha-tocopheryl polyethylene glycol succinate disrupt corneal integrity, and their use requires caution. Thus a nonirritating ophthalmic solution of NSAID could be formulated by dissolving an appropriate water-soluble salt, in the presence of cyclodextrin or tromethamine (if needed) in mildly acidified purified water (if stability permits) with or without benzalkonium chloride and polyvinyl alcohol. Amide prodrugs met with mixed success due to incomplete intraocular hydrolysis. Suspension and ocular inserts appear irritating to the inflamed eye. Oil drop may be a suitable option for insoluble drugs and ointment may be used for sustained effect. Recent studies showed that the use of colloidal nanoparticle formulations and the potent COX 2 inhibitor bromfenac may enhance NSAID efficacy in eye preparations. PMID:18437583

Ahuja, Munish; Dhake, Avinash S; Sharma, Surendra K; Majumdar, Dipak K

2008-04-25

292

Discovering Volatile Events in Your Neighborhood: Local-Area Topic Extraction from Blog Entries  

Microsoft Academic Search

This paper presents a method for the detection of occasional or volatile local events using topic extraction technologies.\\u000a This is a new application of topic extraction technologies that has not been addressed in general location-based services.\\u000a A two-level hierarchical clustering method was applied to topics and their transitions using time-series blog entries collected\\u000a with search queries including place names. According

Masayuki Okamoto; Masaaki Kikuchi

2009-01-01

293

Solitary plaque mycosis fungoides on the penis responding to topical imiquimod therapy.  

PubMed

Mycosis fungoides (MF) presenting in the genitalia is rare. We report a case of long-standing penile MF in a young man. Commonly used treatments for limited plaque MF include topical corticosteroids and ultraviolet light therapy. There are a few anecdotal reports on the use of topical imiquimod in MF. Our patient responded well and remained in complete remission after treatment with topical imiquimod. PMID:17300249

Chiam, L Y T; Chan, Y C

2007-03-01

294

The future of patent information  

Microsoft Academic Search

This article forms part of the debate on how the provision and use of patent information is, and will continue to be, influenced by the rapidly increasing capabilities of the Internet and related information technology, together with a number of major changes in patent law around the world. Topics explored include the relationship between the low cost, limited value-added Internet

Stephen van Dulken

2000-01-01

295

Virtual Schools and Educational Futures.  

ERIC Educational Resources Information Center

Considers issues relating to virtual schools. Topics include types of virtual schools; predictions of the ways technology will change society; quality assurance; costs; parental supervision; teaching without body language cues; socialization and the aims of education; and culture shifts and computer-mediated technology. (LRW)

Russell, Glenn

2001-01-01

296

Tender Topics: Exploring Sensitive Issues with Pre-K through First Grade Children through Read-Alouds  

ERIC Educational Resources Information Center

|The topics including bullying, family diversity, homelessness, disabilities, and incarceration are often referred to as "tender topics." They can be difficult for teachers to explain to or discuss with children. In their work with children, families, and teachers, the authors have seen that it is not necessarily the topic that makes conversations…

Mankiw, Sue; Strasser, Janis

2013-01-01

297

The future of human spaceflight.  

PubMed

After the Apollo Moon program, the international space station represents a further milestone of humankind in space, International follow-on programs like a manned return to the Moon and a first manned Mars Mission can be considered as the next logical step. More and more attention is also paid to the topic of future space tourism in Earth orbit, which is currently under investigation in the USA, Japan and Europe due to its multibillion dollar market potential and high acceptance in society. The wide variety of experience, gained within the space station program, should be used in order to achieve time and cost savings for future manned programs. Different strategies and roadmaps are investigated for space tourism and human missions to the Moon and Mars, based on a comprehensive systems analysis approach. By using DLR's software tool FAST (Fast Assessment of Space Technologies), different scenarios will be defined, optimised and finally evaluated with respect to mission architecture, required technologies, total costs and program duration. This includes trajectory analysis, spacecraft design on subsystem level, operations and life cycle cost analysis. For space tourism, an expected evolutionary roadmap will be described which is initiated by short suborbital tourism and ends with visionary designs like the Space Hotel Berlin and the Space Hotel Europe concept. Furthermore the potential space tourism market, its economic meaning as well as the expected range of the costs of a space ticket (e.g. $50,000 for a suborbital flight) will be analysed and quantified. For human missions to the Moon and Mars, an international 20 year program for the first decades of the next millennium is proposed, which requires about $2.5 Billion per year for a manned return to the Moon program and about $2.6 Billion per year for the first 3 manned Mars missions. This is about the annual budget, which is currently spend by the USA only for the operations of its Space Shuttle fleet which generally proofs the affordability of such ambitious programs after the build-up of the International Space Station, when corresponding budget might become again available. PMID:11669137

Reichert, M

298

Topics in Precipitation Type Forecasting  

NSDL National Science Digital Library

This module presents an overview of various aspects of precipitation type forecasting. It includes sections on microphysics and the ice crystal process, application of partial thickness analysis, application precipitation type analysis.

Spangler, Tim

2005-09-27

299

Staff Burnout (Bibliography Series Topic).  

National Technical Information Service (NTIS)

This annotated Bibliography is an extensive review of the literature in regards to the phenomenon known as burnout. The review includes data searches from the Psychological Abstracts and the National Clearinghouse for Mental Health, utilization of Project...

C. R. Regula C. J. Saft

1982-01-01

300

Alignment and stability of future machines  

SciTech Connect

Leading accelerator laboratories mount serious efforts in alignment and vibration studies concerning stability of future accelerator facilities such as photon and meson factories, future linear colliders (LCs), and hadron supercolliders (HCs). Some 200 publications covered the topic since late 80s, following pioneering works of G.E. Fischer. Four International workshops on accelerator alignment were held since 1989 at SLAC, DESY, CERN and KEK. The SSCL hosted the workshop on vibration control and dynamic alignment (1992). This article briefly covers some present achievements and issues in the field. We discuss major effects and tolerances for the future accelerators, results of measurements up-to-date, correction techniques and make some conclusions.

Shiltsev, V.D.

1996-06-01

301

Topics in Geophysical Fluid Dynamics  

NASA Astrophysics Data System (ADS)

The dynamical evolution of fluids appears in many areas of science. Theoretical understanding and reliable computational description of complex and turbulent flows are one of the grand challenges of science. Although much has been accomplished recently, there is a significant amount of work remaining to get an accurate and effective description of fluid dynamics. This thesis uses two different approaches on different topics in geophysical fluid dynamics. First, rigorous theoretical bounds on the transport of heat are discovered for convection driven both by an internal heat source, and convection driven by an enforced temperature gradient. For stress-free vertical boundaries it is shown that at arbitrary Prandtl number in two dimensions (or at infinite Prandtl number in three dimension) the enhanced heat transport due to convection is bounded as Nu ? Ra5/12 where Ra is a measure of the strength of the driving force. For these same type of boundaries (and under the identical assumptions on the Prandtl number and dimension) with internal heating, the spatially and temporally averaged temperature is bounded from below by H12/17 where H is the strength of the internal heating. For no-slip boundaries at infinite Prandtl number the temperature is bounded by H3/4 log( H )-1/4. Second, methods from numerical analysis and physical intuition are used to test the numerical models intended to describe the evolution of the earth's climate and weather. A stability analysis is carried out to test the numerical stability of divergence damping (a form of numerical dissipation meant to model unresolved sub-grid processes) applied on a latitude-longitude grid. The analysis yields sharp stability constraints, and highlights some of the issues inherent to the choice of grid. A test is also proposed to consider the consistency between the integration of the primitive equations, and the advection of passive tracers in a atmospheric dynamical core. Potential voriticity is used to examine the level of inconsistency between dynamics and tracers in the four dynamical cores present in the National Center for Atmospheric Research's Community Atmosphere Model (CAM5.0).

Whitehead, Jared P.

302

Severe photosensitivity reaction induced by topical diclofenac  

PubMed Central

Albeit uncommon, photosensitivity reaction induced by diclofenac can be an unfortunate adverse reaction complicating its use as a topical analgesic. We here present a case of a patient who suffered such a reaction as a result of exposure to diclofenac, employed as a topical analgesic for low backache. The lesions healed with conservative management without extensive scarring or other complications.

Akat, Pramod B.

2013-01-01

303

Human in vivo pharmacology of topical retinoids  

Microsoft Academic Search

All-trans retinoic acid is used topically for treating a variety of dermatologic conditions ranging from acne to photoaged skin. Although the clinical effects of retinoic acid treatment are often considerable, relatively little is known about the basic mechanisms underlying such effects. With the development of an in vivo human assay we have investigated the pleiotypic effects of topical retinoids from

Christopher E. M. Griffiths; John J. Voorhees

1994-01-01

304

Issues in Selecting Topics for Projects  

Microsoft Academic Search

Unlike units and themes in the early childhood and primary curriculum, projects are defined as children's in-depth investigations of various topics—ideally, topics worthy of the children's time and energy. Usually the project is the work of a whole class, typically working in small groups on subtopics related to the overall one selected. As increasing numbers of teachers and school districts

Lilian G. Katz; Sylvia C. Chard

305

Current Topics in Radiography Number 2  

Microsoft Academic Search

Current Topics in Radiography is an annual publication designed to keep medical radiographers informed about the latest issues that are relevant to their profession. It consists of concise reviews of about 2500 words written by UK experts, often lecturers in radiography. The discussion of controversial topics is avowedly one of its aims. Each chapter has an extensive list of references,

David Hart

1997-01-01

306

Topics in nonlinear wave theory with applications  

Microsoft Academic Search

Selected topics in nonlinear wave theory are discussed and applications to the study of modulational instabilities are presented. A historical survey is given of topics relating to solitons and modulational problems. A method is then presented for generating exact periodic and quasiperiodic solutions to several nonlinear wave equations which have important physical applications. The method is then specialized for the

E. R. Tracy

1984-01-01

307

Topicalization Effects in Memory for Technical Prose.  

National Technical Information Service (NTIS)

The perceived topic of a passage should determine what information is given priority in storage effort for later recall. The topic should also determine how effective a later recall cue should be, in that recall should be best if the cue is the same as th...

D. E. Kieras

1980-01-01

308

Common Topics and Commonplaces of Environmental Rhetoric  

ERIC Educational Resources Information Center

|Common topics are words or phrases used to develop argument, and commonplaces aid memory or catalyze frames of understanding. When used in argumentation, each may help interested parties more effectively communicate valuable scientific and environment-related information. This article describes 12 modern topics of environmental rhetoric,…

Ross, Derek G.

2013-01-01

309

Common Topics and Commonplaces of Environmental Rhetoric  

ERIC Educational Resources Information Center

Common topics are words or phrases used to develop argument, and commonplaces aid memory or catalyze frames of understanding. When used in argumentation, each may help interested parties more effectively communicate valuable scientific and environment-related information. This article describes 12 modern topics of environmental rhetoric,…

Ross, Derek G.

2013-01-01

310

Topic Continuity in Japanese-English Interlanguage.  

ERIC Educational Resources Information Center

Examined how a new topic was introduced, maintained, and changed in the Japanese-English interlanguage data of a 45- minute interview between a native and a non-native speaker of English. Findings revealed that although the topic marking system of the interlanguage shared some features with the first and second languages, it maintained features…

Sasaki, Miyuki

1997-01-01

311

Tracking Multiple Topics for Finding Interesting Articles.  

National Technical Information Service (NTIS)

We introduce multiple topic tracking (MTT) for iScore to better recommend news articles for users with multiple interests and to address changes in user interests over time. As an extension of the basic Rocchio algorithm, traditional topic detection and t...

A. F. Cardenas D. J. Buttler R. K. Pon T. J. Critchlow

2007-01-01

312

A General Evaluation Framework for Topical Crawlers  

Microsoft Academic Search

Abstract: Topical crawlers are becoming important tools to support applications such as specialized Web portals, online searching, and competitive intelligence. As the Web mining field matures, the disparate crawling strategies proposed in the literature will have to be evaluated and compared on common tasks through welldefined performance measures. This paper presents a general framework to evaluate topical crawlers. We identify

Padmini Srinivasan; Filippo Menczer; Gautam Pant

2005-01-01

313

Relevance Models for Topic Detection and Tracking  

Microsoft Academic Search

We extend relevance modeling to the link detection task of Topic Detection and Tracking (TDT) and show that it substantially improves performance. Relevance modeling, a statistical language modeling technique related to query expansion, is used to enhance the topic model estimate asso- ciated with a news story, boosting the probability of words that are associated with the story even when

Victor Lavrenko; James Allan; Edward DeGuzman; Daniel LaFlamme; Veera Pollard; Stephen Thomas

2002-01-01

314

Types of topics in German and Italian  

Microsoft Academic Search

This paper investigates the phonological and syntactic realization of topics in German and Italian. Based on a detailed intonational and syntactic analysis of corpus data, it is shown that topics are not fully recursive (contra Rizzi 1997), but fall into three types that are distinguished phonologically and realized in different syntactic positions. We argue that there is a systematic correlation

Mara Frascarelli; Roland Hinterhölzl

315

Severe photosensitivity reaction induced by topical diclofenac.  

PubMed

Albeit uncommon, photosensitivity reaction induced by diclofenac can be an unfortunate adverse reaction complicating its use as a topical analgesic. We here present a case of a patient who suffered such a reaction as a result of exposure to diclofenac, employed as a topical analgesic for low backache. The lesions healed with conservative management without extensive scarring or other complications. PMID:24014923

Akat, Pramod B

2013-07-01

316

Secondary Voc Ed: Preparing the Future Workforce.  

ERIC Educational Resources Information Center

The author discusses the current state of secondary vocational education in Wisconsin, where each public secondary school is required to offer vocational education. Topics covered include (1) goals and expectations, (2) curriculum development, and (3) educational equity. (CH)

Dignan, Richard

1987-01-01

317

Microbiological profile of a new topical antibacterial: retapamulin ointment 1%.  

PubMed

Retapamulin is a new topical pleuromutilin antibiotic for the treatment of skin and skin-structure infections, including impetigo. In vitro studies indicate that retapamulin has a unique mode of action that minimizes the potential for target-specific cross-resistance with other antibacterials and a limited potential for resistance development. Its spectrum of activity includes the most likely causative pathogens Staphylococcus aureus and Streptococcus pyogenes. In the Global Surveillance Program, retapamulin was highly active in vitro, including against strains of S. aureus resistant to methicillin, mupirocin or fusidic acid. In clinical studies, retapamulin was noninferior to fusidic acid and oral cefalexin, achieving per-pathogen success rates of 86-99%. Topical retapamulin has a good safety profile and is associated with high patient compliance. PMID:19344241

Scangarella-Oman, Nicole E; Shawar, Ribhi M; Bouchillon, Samuel; Hoban, Daryl

2009-04-01

318

National Writing Project: Resource Topics  

NSDL National Science Digital Library

The National Writing Project website compiles a wealth of resources that have appeared in the archive as well as its publications over the years. The materials here are divided into eight sections, including Teaching Writing, Teaching Reading, and Standards and Assessment. The Teaching Writing area contains information aplenty on areas such as Grammar and Usage, Special Needs, and Digital Writing. The Digital Writing section includes strategies for working in a technology-rich environment and incorporating short, intense writing activities into the classroom. Another helpful section is the Being a Writer area, which includes Fiction and Poetry Publishing Resources and material on starting and maintaining a writersâ group. The site is rounded out by a series of links to additional websites for general consideration.

2012-01-01

319

System and method for classifying legal concepts using legal topic scheme  

US Patent & Trademark Office Database

An economic, scalable machine learning system and process perform document (concept) classification with high accuracy using large topic schemes, including large hierarchical topic schemes. One or more highly relevant classification topics is suggested for a-given document (concept) to be classified. The invention includes training and concept classification processes. The invention also provides methods that may be used as part of the training and/or concept classification processes, including: a method of scoring the relevance of features in training concepts, a method of ranking concepts based on relevance score, and a method of voting on topics associated with an input concept. In a preferred embodiment, the invention is applied to the legal (case law) domain, classifying legal concepts (rules of law) according to a proprietary legal topic classification scheme (a hierarchical scheme of areas of law).

2002-12-31

320

Taboo topics in addiction treatmentAn empirical review of clinical folklore  

Microsoft Academic Search

This article reviews II taboo topics, that is, research findings that question traditional assumptions and teachings of addiction treatment. These topics include: (I) the lack of empirical support for the Minnesota Model; (2) questions about the necessity of Alcoholics Anonymous for maintaining abstinence; (3) the existence of spontaneous remission; (4) the detrimental aspects of labeling; (5) the value of addicted

Emil J. Chiauzzi; Steven Liljegren

1993-01-01

321

Special Topics Courses - A Happy Medium between Mini-Courses and Full-Coverage Courses.  

ERIC Educational Resources Information Center

|Describes a special topics program which allows students some choice in content to be studied. Topics include Continental Drift and Ice Ages, Geology and National Parks, the Coast of South Carolina, and Medical Geology. Student evaluations indicate positive attitudes towards the program. (MA)|

Carpenter, John R.; And Others

1979-01-01

322

Developing an Action Plan for Integrating Sleep Topics into the Medical School Curriculum  

Microsoft Academic Search

Sleep disorders are prevalent although they go unrecognized by clinicians, partially because of limited exposure to sleep medicine topics during medical school. Sleep topics can be integrated during both the preclinical and clinical years of the medical school curriculum by developing an integration strategy and action plan. Components of the action plan include examining the current medical school curriculum and

Susan M. Harding; Eta S. Berner

2002-01-01

323

Teachers as Curriculum Decision Makers: The Selection of Topics for High School Physics.  

ERIC Educational Resources Information Center

|A group of 26 high-school physics teachers completed a card-sorting task to prioritize their choices of topics to include in the physics curriculum. Mechanics, electricity, and magnetism emerged as most important. Covering these topics conflicted with teachers' goals to impart deep conceptual understanding of physics in their students. (33…

Feldman, Allan; Kropf, Aaron

1999-01-01

324

A Review of Subject Matter Topics Researched in Agricultural and Extension Education.  

ERIC Educational Resources Information Center

|Analysis of 402 articles in the Journal of Agricultural Education and 451 National Agricultural Education Research Meeting papers (1986-1996) yielded 30 categories of topics. The top five were secondary agriculture programs, learning styles, extension education, professionalism, and ag mechanics/engineering. Emerging topics included distance…

Radhakrishna, Rama B.; Xu, Wenwei

1997-01-01

325

Topics in B-Physics.  

National Technical Information Service (NTIS)

We discuss a few issues in the burgeoning field of physics of hadrons containing the b-quark. These include: A simple parameterization of the Kobayashi-Maskawa matrix featuring a triangle in the complex plane, a review of B/sub s/ and B/sub d/ mixing with...

J. D. Bjorken

1988-01-01

326

Topic in Depth - Embedded Systems  

NSDL National Science Digital Library

Embedded systems are dedicated computers designed to perform a specific task. They are usually fairly simple devices that are used in areas where powerful, customizable computers are unnecessary; however, they can also be quite complex on occasion. Embedded systems can be found almost anywhere, including automobiles and cellular phones, and their importance is reflected in their near omnipresence.

2010-09-09

327

The Future of Criterion-Related Validity.  

National Technical Information Service (NTIS)

As a result of rejection by personnel psychologists of the erroneous law of small numbers and of the adoption of correct inferential procedures, the future of criterion-related validity promises to be bright. Probable future developments include: (a) wide...

F. L. Schmidt J. E. Hunter

1980-01-01

328

Topic maps for archiving space plant experiments  

NASA Astrophysics Data System (ADS)

The increasing amount of data collected during Space flight experiments, especially on the ISS, requires a new approach for data archiving. The "ULISSE" project, funded by the European Commission, combines the knowledge of the User Support Operation Centers (USOCs) of the ISS and their industrial partners to build up a database for the integration and dissemination of Space experiments. For plant experiments in Space, the N-USOC in Trondheim (Norway) is responsible to collect and implement the needs of scientists working in the field of plant biology for this bio-informatics tool. Each experiment can be found in a topic map providing interfaces to other experiments or other topics. Topic maps describe among others the ex-periment environment in orbit or on ground, experimental methods, hardware and software, biological processes, and experimental results. Each of these topics needs to be identified by an unambiguous definition, usually a link to a database like a thesaurus or an ontology. A survey was done to see in which of the common ontology databases suitable definitions of the topic names of the N-USOC Topic Map could be found. Thus, the draft N-USOC Topic Map could be linked almost completely to Web based definitions. This will allow embedding Space plant biology experiments into public data management systems. Credits: European Commission (FP7/2007-2013, grant agreement n218815).

Brinckmann, Enno; Karoliussen, Irene; Hauan, Tore Martin; Fossum, Knut R.

329

Current topics in tardive dyskinesia in Japan.  

PubMed

This article reviews current topics in tardive dyskinesia (TD), a movement disorder associated with the prolonged use of neuroleptic agents, especially therapeutic and preventive strategies which have been or are now being studied in Japan. Tardive dyskinesia has become a major problem in the clinical psychiatric field since the early 1970s in Japan, lagging behind Western countries by more than 10 years. The average prevalence rate of TD has been estimated as 7.7% in Japan, while it has been reported in the English literature at around 15 to 20%. Clinical trials of treatments for TD have been or are now being performed in Japan with a number of novel compounds, such as ceruletide, meclofenoxate, and rolipram; however, no effective treatment has yet been established and measures to prevent TD have therefore been emphasized. These include (i) the development of new antipsychotic drugs which are free from TD, (ii) the identification of risk factors from prospective longitudinal studies, and (iii) the investigation of genetic variations that could act as a marker to identify especially vulnerable patients within the whole population of patients who need neuroleptic therapy. PMID:8726107

Inada, T; Yagi, G

1995-12-01

330

Topical treatment of common superficial tinea infections.  

PubMed

Tinea infections are superficial fungal infections caused by three species of fungi collectively known as dermatophytes. Commonly these infections are named for the body part affected, including tinea corporis (general skin), tinea cruris (groin), and tinea pedis (feet). Accurate diagnosis is necessary for effective treatment. Diagnosis is usually based on history and clinical appearance plus direct microscopy of a potassium hydroxide preparation. Culture or histologic examination is rarely required for diagnosis. Treatment requires attention to exacerbating factors such as skin moisture and choosing an appropriate antifungal agent. Topical therapy is generally successful unless the infection covers an extensive area or is resistant to initial therapy. In these cases, systemic therapy may be required. Tinea corporis and cruris infections are usually treated for two weeks, while tinea pedis is treated for four weeks with an azole or for one to two weeks with allylamine medication. Treatment should continue for at least one week after clinical clearing of infection. Newer medications require fewer applications and a shorter duration of use. The presence of inflammation may necessitate the use of an agent with inherent anti-inflammatory properties or the use of a combination antifungal/steroid agent. The latter agents should be used with caution because of their potential for causing atrophy and other steroid-associated complications. PMID:12046779

Weinstein, Andrew; Berman, Brian

2002-05-15

331

Digital Social Network Mining for Topic Discovery  

NASA Astrophysics Data System (ADS)

Networked computers are expanding more and more around the world, and digital social networks becoming of great importance for many people's work and leisure. This paper mainly focused on discovering the topic of exchanging information in digital social network. In brief, our method is to use a hierarchical dictionary of related topics and words that mapped to a graph. Then, with comparing the extracted keywords from the context of social network with graph nodes, probability of relation between context and desired topics will be computed. This model can be used in many applications such as advertising, viral marketing and high-risk group detection.

Moradianzadeh, Pooya; Mohi, Maryam; Sadighi Moshkenani, Mohsen

332

A Review of Selected Nanotechnology Topics and Their Potential Military Applications  

Microsoft Academic Search

This report presents the review of progress in selected nanotechology topics and some possible applications. We survey four major branches within the field: nanotubes, quantum dots, nanomaterials and nanodevices. For each of these, we review the underlying scientific concepts, potential enabling technologies and current limitations to the realisation of nanotechnology applications. Possible implications for the future Land Force are discussed

Jun Wang; Peter J Dortmans

333

Toward the Greening of Our Minds: A New Special Topics Course  

ERIC Educational Resources Information Center

A new special-topics course on green chemistry would help students to critically evaluate policy decisions in an environmentally conscientious manner. The actively acquired knowledge would allow students to spread the word about green chemistry in the long term to the world, where they would pursue their future goals of life.

Marteel-Parrish, Anne E.

2007-01-01

334

Toward the Greening of Our Minds: A New Special Topics Course  

ERIC Educational Resources Information Center

|A new special-topics course on green chemistry would help students to critically evaluate policy decisions in an environmentally conscientious manner. The actively acquired knowledge would allow students to spread the word about green chemistry in the long term to the world, where they would pursue their future goals of life.|

Marteel-Parrish, Anne E.

2007-01-01

335

Future Climate Analysis  

SciTech Connect

This report documents an analysis that was performed to estimate climatic variables for the next 10,000 years by forecasting the timing and nature of climate change at Yucca Mountain, Nevada, the site of a repository for spent nuclear fuel and high-level radioactive waste. The future-climate estimates are based on an analysis of past-climate data from analog meteorological stations, and this report provides the rationale for the selection of these analog stations. The stations selected provide an upper and a lower climate bound for each future climate, and the data from those sites will provide input to the following reports: ''Simulation of Net Infiltration for Present-Day and Potential Future Climates'' (BSC 2004 [DIRS 170007]), ''Total System Performance Assessment (TSPA) Model/Analysis for the License Application'' (BSC 2004 [DIRS 168504]), ''Features, Events, and Processes in UZ Flow and Transport'' (BSC 2004 [DIRS 170012]), and ''Features, Events, and Processes in SZ Flow and Transport'' (BSC 2004 [DIRS 170013]). Forecasting long-term future climates, especially for the next 10,000 years, is highly speculative and rarely attempted. A very limited literature exists concerning the subject, largely from the British radioactive waste disposal effort. The discussion presented here is one available forecasting method for establishing upper and lower bounds for future climate estimates. The selection of different methods is directly dependent on the available evidence used to build a forecasting argument. The method used here involves selecting a particular past climate from many past climates, as an analog for future climate. While alternative analyses are possible for the case presented for Yucca Mountain, the evidence (data) used would be the same and the conclusions would not be expected to drastically change. Other studies might develop a different rationale or select other past climates resulting in a different future climate analog. Other alternative approaches could include simulation of climate over the 10,000-year period; however, this modeling extrapolation is well beyond the bounds of current scientific practice and would not provide results with better confidence. A corroborative alternative approach may be found in ''Future Climate Analysis-10,000 Years to 1,000,000 Years After Present'' (Sharpe 2003 [DIRS 161591]). The current revision of this report is prepared in accordance with ''Technical Work Plan for: Unsaturated Zone Flow Analysis and Model Report Integration'' (BSC 2004 [DIRS 169654]).

C. G. Cambell

2004-09-03

336

EDITORIAL: International Workshop on Current Topics in Monte Carlo Treatment Planning  

NASA Astrophysics Data System (ADS)

The use of Monte Carlo particle transport simulations in radiotherapy was pioneered in the early nineteen-seventies, but it was not until the eighties that they gained recognition as an essential research tool for radiation dosimetry, health physics and later on for radiation therapy treatment planning. Since the mid-nineties, there has been a boom in the number of workers using MC techniques in radiotherapy, and the quantity of papers published on the subject. Research and applications of MC techniques in radiotherapy span a very wide range from fundamental studies of cross sections and development of particle transport algorithms, to clinical evaluation of treatment plans for a variety of radiotherapy modalities. The International Workshop on Current Topics in Monte Carlo Treatment Planning took place at Montreal General Hospital, which is part of McGill University, halfway up Mount Royal on Montreal Island. It was held from 3-5 May, 2004, right after the freezing winter has lost its grip on Canada. About 120 workers attended the Workshop, representing 18 countries. Most of the pioneers in the field were present but also a large group of young scientists. In a very full programme, 41 long papers were presented (of which 12 were invited) and 20 posters were on display during the whole meeting. The topics covered included the latest developments in MC algorithms, statistical issues, source modelling and MC treatment planning for photon, electron and proton treatments. The final day was entirely devoted to clinical implementation issues. Monte Carlo radiotherapy treatment planning has only now made a slow entrée in the clinical environment, taking considerably longer than envisaged ten years ago. Of the twenty-five papers in this dedicated special issue, about a quarter deal with this topic, with probably many more studies to follow in the near future. If anything, we hope the Workshop served as an accelerator for more clinical evaluation of MC applications. The remainder of the papers in this issue demonstrate that there is still plenty of work to be undertaken on other topics such as source modelling, calculation speed, data analysis, and development of user-friendly applications. We acknowledge the financial support of the National Cancer Institute of Canada, the Institute of Cancer Research of the Canadian Institutes of Health Research, the Research Grants Office and the Post Graduate Student Society of McGill University, and the Institute of Physics Publishing (IOPP). A final word of thanks goes out to all of those who contributed to the successful Workshop: our local medical physics students and staff, the many colleagues who acted as guest associate editors for the reviewing process, the IOPP staff, and the authors who generated new and exciting work.

Verhaegen, Frank; Seuntjens, Jan

2005-03-01

337

Summary of SMIRT20 Preconference Topical Workshop – Identifying Structural Issues in Advanced Reactors  

SciTech Connect

Summary of SMIRT20 Preconference Topical Workshop – Identifying Structural Issues in Advanced Reactors William Richins1, Stephen Novascone1, and Cheryl O’Brien1 1Idaho National Laboratory, US Dept. of Energy, Idaho Falls, Idaho, USA, e-mail: William.Richins@inl.gov The Idaho National Laboratory (INL, USA) and IASMiRT sponsored an international forum Nov 5-6, 2008 in Porvoo, Finland for nuclear industry, academic, and regulatory representatives to identify structural issues in current and future advanced reactor design, especially for extreme conditions and external threats. The purpose of this Topical Workshop was to articulate research, engineering, and regulatory Code development needs. The topics addressed by the Workshop were selected to address critical industry needs specific to advanced reactor structures that have long lead times and can be the subject of future SMiRT technical sessions. The topics were; 1) structural/materials needs for extreme conditions and external threats in contemporary (Gen. III) and future (Gen. IV and NGNP) advanced reactors and 2) calibrating simulation software and methods that address topic 1 The workshop discussions and research needs identified are presented. The Workshop successfully produced interactive discussion on the two topics resulting in a list of research and technology needs. It is recommended that IASMiRT communicate the results of the discussion to industry and researchers to encourage new ideas and projects. In addition, opportunities exist to retrieve research reports and information that currently exists, and encourage more international cooperation and collaboration. It is recommended that IASMiRT continue with an off-year workshop series on select topics.

William Richins; Stephen Novascone; Cheryl O'Brien

2009-08-01

338

Actinides and Rare Earths Topical Conference (Code AC)  

SciTech Connect

Actinide and the Rare Earth materials exhibit many unique and diverse physical, chemical and magnetic properties, in large part because of the complexity of their f electronic structure. This Topical Conference will focus upon the chemistry, physics and materials science in Lanthanide and Actinide materials, driven by 4f and 5f electronic structure. Particular emphasis will be placed upon 4f/5f magnetic structure, surface science and thin film properties. For the actinides, fundamental actinide science and its role in resolving technical challenges posed by actinide materials will be stressed. Both basic and applied experimental approaches, including synchrotron-radiation-based investigations, as well as theoretical modeling and computational simulations, are planned to be part of the Topical Conference. Of particular importance are the issues related to the potential renaissance in Nuclear Fuels, including synthesis, oxidation, corrosion, intermixing, stability in extreme environments, prediction of properties via benchmarked simulations, separation science, environmental impact and disposal of waste products.

Tobin, J G

2009-11-24

339

Geotechnical support and topical studies for nuclear waste geologic repositories  

SciTech Connect

The present report lists the technical reviews and comments made during the fiscal year 1988 and summarizes the technical progress of the topical studies. In the area of technical assistance, there were numerous activities detailed in the next section. These included 24 geotechnical support activities, including reviews of 6 Study Plans (SP) and participation in 6 SP Review Workshops, review of one whole document Site Characterization Plan (SCP) and participation in the Assembled Document SCP Review Workshops by 6 LBL reviewers; the hosting of a DOE program review, the rewriting of the project statement of work, 2 trips to technical and planning meetings; preparation of proposed work statements for two new topics for DOE, and 5 instances of technical assistance to DOE. These activities are described in a Table in the following section entitled Geoscience Technical Support for Nuclear Waste Geologic Repositories.''

Not Available

1989-01-01

340

Future makers or future takers? A scenario analysis of climate change and the Great Barrier Reef  

Microsoft Academic Search

The extent to which nations and regions can actively shape the future or must passively respond to global forces is a topic of relevance to current discourses on climate change. In Australia, climate change has been identified as the greatest threat to the ecological resilience of the Great Barrier Reef, but is exacerbated by regional and local pressures. We undertook

Erin Bohensky; James R. A. Butler; Robert Costanza; Iris Bohnet; Aurélie Delisle; Katharina Fabricius; Margaret Gooch; Ida Kubiszewski; George Lukacs; Petina Pert; Eric Wolanski

2011-01-01

341

Special Topics in Water Science (Water Pollution)  

MedlinePLUS

... Basics Water Properties Water Cycle Surface Water Groundwater Water Quality Water Use Activities Photos Q&A Teachers Contact ... explore other water-science topic areas, such as water quality, urbanization and water, saline water, watersheds, runoff, and ...

342

Active Research Topics in Human Machine Interfaces.  

National Technical Information Service (NTIS)

This paper identifies active research topics concerning human machine interfaces for intelligent machine systems. The paper was compiled by performing a series of literature searches and organizing the information according to the author's interest in bet...

M. J. McDonald

2000-01-01

343

Topical Microbicides: Preventing Sexually Transmitted Diseases.  

National Technical Information Service (NTIS)

Few good strategies exist for preventing the spread of sexually transmitted diseases (STDs). Indeed, women currently have no way to protect themselves from STDs that does not require male cooperation. Topical microbicides could change this. If you have no...

2003-01-01

344

Science Base for Materials Processing - Selected Topics.  

National Technical Information Service (NTIS)

The report presents the highlights of a workshop on four selected topics, namely, high-speed metal removal, metal deformation processing, advanced composites, and high-modulus polymers. The objectives of the workshop were to identify areas of materials pr...

1979-01-01

345

International Committee of the Red Cross: Issues and Topics: Landmines  

NSDL National Science Digital Library

This site provides interested Internauts with valuable information on the terrific problem of the millions of undetonated landmines world wide. The International Committee of the Red Cross offers many resources on the topic, including a recently released Information Paper: Anti-personnel mines: An overview (under The Problem). The Ottawa declaration and Global Plan of Action (1996) can be found under the International Humanitarian Law section. There is also a photo essay entitled Seven Days in a Minefield.

1997-01-01

346

[Successful treatment of diabetic gustatory hyperhidrosis with topical glycopyrrolate].  

PubMed

Gustatory hyperhidrosis is a condition characterised by excessive craniofacial sweating in relation to food intake and is associated with diabetic neuropathy. The existing guidelines for treatment of this condition include antiperspirants, oral anticholinergic treatment, ionophoresis, botulinum toxin injections and endothoracic surgery. In this case a patient with diabetes suffering from gustatory hyperhidrosis was treated successfully with topical glycopyrrolate, an anticholinergic agent applied directly on the affected area. PMID:21893005

Lund, Ninna Sřnderby; Maxel, Trine; Rungby, Jřrgen

2011-09-01

347

Asbestos removal: Shippingport Station Decommissioning Project: Topical report  

SciTech Connect

This topical report is a synopsis of the asbestos insulation removal performed at the Shippingport Station Decommissioning Project (SSDP). The information is provided, as a part of the Technology Transfer Program, to document the removal of asbestos insulation at a nuclear power station decommissioning project. The report covers the scope of work, regulations, engineering decisions, removal methods, lessons learned, and summaries from the detailed data base including manhours, asbestos removal volumes, radiation exposures, and asbestos airborne concentrations. 5 refs., 2 figs., 7 tabs.

Not Available

1988-07-06

348

SETS: search enhanced by topic segmentation  

Microsoft Academic Search

We present SETS, an architecture for efficient search in peer-to-peer networks, building upon ideas drawn from machine learning and social network theory. The key idea is to arrange participating sites in a topic-segmented overlay topology in which most connections are short-distance, connecting pairs of sites with similar content. Topically focused sets of sites are then joined together into a single

Mayank Bawa; Gurmeet Singh Manku; Prabhakar Raghavan

2003-01-01

349

Topical Gene Delivery to Murine Skin  

Microsoft Academic Search

We topically applied naked plasmid DNA containing the luciferase or chloramphenicol acetyltransferase cDNA directly to mouse skin. Gene expression was detected in skin samples as early as 4 h after DNA application, plateaued from 16 to 72 h post-application, and had decreased significantly by 7 d post-application. Reporter gene activity following topical DNA delivery was comparable with that produced by

Wei Hong Yu; Mohammed Kashani-Sabet; Denny Liggitt; Dan Moore; Timothy D. Heath; Robert J. Debs

1999-01-01

350

Treatment of pediculosis capitis with topical albendazole.  

PubMed

Pediculosis capitis, or head lice infestation, caused by Pediculus humanus capitis, is a common and ubiquitous health concern. Increasing resistance and treatment failures are reported with available topical pediculicides and may prove challenging to manage. Recent data indicate that the oral anti-helmintic agents thiabendazole and albendazole could represent new therapeutic options against pediculosis capitis. We report a novel treatment modality in four patients with head lice who were successfully treated with a topical application of albendazole. PMID:20964575

Ayoub, Nakhlé; Maatouk, Ismaël; Merhy, Martin; Tomb, Roland

2010-10-22

351

TOPICAL REVIEW: Magnetic surface nanostructures  

NASA Astrophysics Data System (ADS)

Recent trends in the emerging field of surface-supported magnetic nanostructures are reviewed. Current strategies for nanostructure synthesis are summarized, followed by a predominantly theoretical description of magnetic phenomena in surface magnetic structures and a review of experimental research in this field. Emphasis is on Fe- or Co-based nanostructures in various low-dimensional geometries, which are studied as model systems to explore the effects of dimensionality, atomic coordination, chemical bonds, alloying and, most importantly, interactions with the supporting substrate on the magnetism. This review also includes a discussion of closely related systems, such as 3d element impurities integrated into organic networks, surface-supported Fe-based molecular magnets, Kondo systems or 4d element nanostructures that exhibit emergent magnetism, thereby bridging the traditional areas of surface science, molecular physics and nanomagnetism.

Enders, A.; Skomski, R.; Honolka, J.

2010-11-01

352

Human action recognition by semilatent topic models.  

PubMed

We propose two new models for human action recognition from video sequences using topic models. Video sequences are represented by a novel "bag-of-words" representation, where each frame corresponds to a "word." Our models differ from previous latent topic models for visual recognition in two major aspects: first of all, the latent topics in our models directly correspond to class labels; second, some of the latent variables in previous topic models become observed in our case. Our models have several advantages over other latent topic models used in visual recognition. First of all, the training is much easier due to the decoupling of the model parameters. Second, it alleviates the issue of how to choose the appropriate number of latent topics. Third, it achieves much better performance by utilizing the information provided by the class labels in the training set. We present action classification results on five different data sets. Our results are either comparable to, or significantly better than previously published results on these data sets. PMID:19696448

Wang, Yang; Mori, Greg

2009-10-01

353

Space Resources for Teachers: Biology, Including Suggestions for Classroom Activities and Laboratory Experiments.  

ERIC Educational Resources Information Center

This compilation of resource units concerns the latest developments in space biology. Some of the topics included are oxygen consumption, temperature, radiation, rhythms, weightlessness, acceleration and vibration stress, toxicity, and sensory and perceptual problems. Many of the topics are interdisciplinary and relate biology, physiology,…

Lee, Tom E.; And Others

354

Modern approach to topical treatment of aging skin.  

PubMed

The main processes involved in skin aging are intrinsic and extrinsic. Apart from them, so called stochastic aging connotes cell damage caused by metabolic processes, free radicals and cosmic irradiation. The clinical expression of intrinsic aging include smooth, dry, and thinned skin with accentuated expression lines. It is inevitable and time dependent. Extrinsically aged skin shows signs of photodamage which include appearance of wrinkles, pigmented lesions, actinic keratoses and patchy hypopigmentations. Therapeutic modalities imply photoprotection with sunscreens that prevent sunburns and block ultraviolet irradiation. Other modalities include use of retinoids which regulate gene transcription with subsequent cellular differentiation and proliferation. The topical and peroral administration of network antioxidants, such as vitamin E and C, coenzyme Q10, alpha-lipoic acid and glutathione, enhance antiaging effect. The other antioxidants such as green tea, dehydroepiandrosterone, melatonin, selenium and resveratrol, have also antiaging and anti-inflammatory effects. Topical bleaching agents such as hydroquinone, kojic acid and azelaic acid can reduce signs of aging. Studies confirm the efficacy of these topical agents in combination with superficial and/or medium depth or deep peeling agents for photodamaged skin treatment. Indications for type of chemical peels according to various clinical diagnosis are done, as well as advantages and disadvantages of different types of chemical peels. PMID:20977120

Puizina-Ivi?, Neira; Miri?, Lina; Carija, Antoanela; Karlica, Dobrila; Marasovi?, Dujomir

2010-09-01

355

Vaccines of the future.  

PubMed

Vaccines of the future can be divided into three broad groups, namely those of the near future (<10 years); the medium-term future (10-19 years); and the long-term future (20-50 years). For the near future, there is some "low hanging fruit" which is clearly on the horizon, such as a Vi-conjugate vaccine for typhoid or a protein-based vaccine for Neisseria meningitidis serogroup B. Just slightly more distant will be vaccines for shigellosis and a common protein vaccine for Streptococcus pneumoniae. Also in this group, but not as far advanced, will be a vaccine for Group A streptococcus. I place vaccines for the "big three", malaria, tuberculosis and HIV/AIDS in the medium term basket. The sporozoite malaria vaccine RTS-S is closest, but surely a definitive malaria vaccine will also require antigens from other stages of the life cycle. A tuberculosis vaccine will be either a re-engineered BCG; or a molecular vaccine with several protein antigens; or one based on prime-boost strategies. What will delay this is the high cost of clinical trials. For HIV/AIDS, the partial success of the Sanofi-Pasteur prime-boost vaccine has given some hope. I still place much faith in antibody-based vaccines and especially on mimotopes of the env transitional state assumed after initial CD4 binding. Monoclonal antibodies are also leading us in interesting directions. Longer term, the vaccine approach will be successful for autoimmune diseases, e.g. juvenile diabetes and coeliac disease. Cancer vaccines are also briefly surveyed. Adjunct issues needing to be addressed include more extensive combinations; alternate delivery systems; and more intelligently designed adjuvants based on knowledge of the innate immune system. PMID:22185835

Nossal, G J V

2011-12-18

356

Two Topics in Nuclear Physics  

NASA Astrophysics Data System (ADS)

A longstanding problem with the Skyrme Model of the nucleon is that in a classical treatment the potential found in the spin-isospin independent channel is repulsive and thereby in contradiction with observation. In the first part of this thesis, we analyze the central part of the nucleon-nucleon potential. The analysis is done following a method proposed by Yamagishi and Zahed involving a double expansion in the soliton separation and the coupling constant. We first illustrate how to apply the method to simple 1 + 1 dimensional models. Following a brief review of the Skyrmion, we sketch how to derive the nucleon -nucleon interaction in the aforementioned expansion. We then present the results of a detailed numerical analysis of the nucleon-nucleon potential in the spin-isospin independent channel in the Skyrme Model. For undistorted pion fluctuations, our numerical results indicate that the pion induced attraction in the central channel is strong enough to cancel the conventional repulsion in the intermediate range to leading order. The case of distorted pion fluctuations is briefly discussed. In the second part of this thesis we investigate the possibility that a phase of matter containing a Bose -Einstein condensate of kaons can exist in the dense interior of neutron stars. We specifically address the question of whether such condensation can occur solely through the S-wave interaction of kaons with nucleons. The starting point of our analysis is chiral lagrangian of Kaplan and Nelson. We include nucleon-nucleon interactions by using the simple parametrization given recently by Prakash, Ainsworth and Lattimer, and include electrons and muons in beta-equilibrium with the neutron star matter. It is found that the critical density for kaon condensation is in the range (2.3-5.0)rho_0, where rho_0 = 0.16fm ^{-3} is the density of nuclear matter. The critical density depends largely on the value of the strangeness content of the proton < | ss>_{P}, the size of which is controversial. We derive the equation of state above the condensation threshold in the mean field approximation and investigate particle densities in the condensed state. We show that neutron star matter in the presence of a kaon condensate is sufficiently stiff to support a 1.4M_odot star, and is therefore compatible with observed neutron star masses. The neutron star contains a core of matter with a kaon condensate and a large fraction of protons. It is suggested that positrons might be produced inside the core and that kaon condensation might serve as a catalyst for fast neutron star cooling via the direct URCA process.

Thorsson, Vesteinn Atli

1992-01-01

357

Topical Review: Polymer gel dosimetry  

PubMed Central

Polymer gel dosimeters are fabricated from radiation sensitive chemicals which, upon irradiation, polymerize as a function of the absorbed radiation dose. These gel dosimeters, with the capacity to uniquely record the radiation dose distribution in three-dimensions (3D), have specific advantages when compared to one-dimensional dosimeters, such as ion chambers, and two-dimensional dosimeters, such as film. These advantages are particularly significant in dosimetry situations where steep dose gradients exist such as in intensity-modulated radiation therapy (IMRT) and stereotactic radiosurgery. Polymer gel dosimeters also have specific advantages for brachytherapy dosimetry. Potential dosimetry applications include those for low-energy x-rays, high-linear energy transfer (LET) and proton therapy, radionuclide and boron capture neutron therapy dosimetries. These 3D dosimeters are radiologically soft-tissue equivalent with properties that may be modified depending on the application. The 3D radiation dose distribution in polymer gel dosimeters may be imaged using magnetic resonance imaging (MRI), optical-computerized tomography (optical-CT), x-ray CT or ultrasound. The fundamental science underpinning polymer gel dosimetry is reviewed along with the various evaluation techniques. Clinical dosimetry applications of polymer gel dosimetry are also presented.

Baldock, C; De Deene, Y; Doran, S; Ibbott, G; Jirasek, A; Lepage, M; McAuley, K B; Oldham, M; Schreiner, L J

2010-01-01

358

Selected Topics in Graphene Physics  

NASA Astrophysics Data System (ADS)

Graphene research is currently one of the largest fields in condensed matter. Due to its unusual electronic spectrum with Dirac-like quasiparticles, and the fact that it is a unique example of a metallic membrane, graphene has properties that have no match in standard solid-state textbooks. In these lecture notes, I discuss some of these properties that are not covered in detail in recent reviews (Castro Neto AH, Guinea F, Peres NMR, Novoselov KS, Geim AK (2009) Rev Mod Phys 81:109). We study the particular aspects of the physics/chemistry of carbon that influence the properties of graphene; the basic features of graphene's band structure including the ? and ? bands; the phonon spectra in free floating graphene; the effects of a substrate on the structural properties of graphene; and the effect of deformations in the propagation of electrons. The objective of these notes is not to provide an unabridged theoretical description of graphene but to point out some of the peculiar aspects of this material.

Castro Neto, Antonio H.

359

TOPICAL REVIEW: Polymer gel dosimetry  

NASA Astrophysics Data System (ADS)

Polymer gel dosimeters are fabricated from radiation sensitive chemicals which, upon irradiation, polymerize as a function of the absorbed radiation dose. These gel dosimeters, with the capacity to uniquely record the radiation dose distribution in three-dimensions (3D), have specific advantages when compared to one-dimensional dosimeters, such as ion chambers, and two-dimensional dosimeters, such as film. These advantages are particularly significant in dosimetry situations where steep dose gradients exist such as in intensity-modulated radiation therapy (IMRT) and stereotactic radiosurgery. Polymer gel dosimeters also have specific advantages for brachytherapy dosimetry. Potential dosimetry applications include those for low-energy x-rays, high-linear energy transfer (LET) and proton therapy, radionuclide and boron capture neutron therapy dosimetries. These 3D dosimeters are radiologically soft-tissue equivalent with properties that may be modified depending on the application. The 3D radiation dose distribution in polymer gel dosimeters may be imaged using magnetic resonance imaging (MRI), optical-computerized tomography (optical-CT), x-ray CT or ultrasound. The fundamental science underpinning polymer gel dosimetry is reviewed along with the various evaluation techniques. Clinical dosimetry applications of polymer gel dosimetry are also presented.

Baldock, C.; De Deene, Y.; Doran, S.; Ibbott, G.; Jirasek, A.; Lepage, M.; McAuley, K. B.; Oldham, M.; Schreiner, L. J.

2010-03-01

360

Flammable gas project topical report  

SciTech Connect

The flammable gas safety issue was recognized in 1990 with the declaration of an unreviewed safety question (USQ) by the U. S. Department of Energy as a result of the behavior of the Hanford Site high-level waste tank 241-SY-101. This tank exhibited episodic releases of flammable gas that on a couple of occasions exceeded the lower flammability limit of hydrogen in air. Over the past six years there has been a considerable amount of knowledge gained about the chemical and physical processes that govern the behavior of tank 241-SY-1 01 and other tanks associated with the flammable gas safety issue. This report was prepared to provide an overview of that knowledge and to provide a description of the key information still needed to resolve the issue. Items covered by this report include summaries of the understanding of gas generation, retention and release mechanisms, the composition and flammability behavior of the gas mixture, the amounts of stored gas, and estimated gas release fractions for spontaneous releases. `Me report also discusses methods being developed for evaluating the 177 tanks at the Hanford Site and the problems associated with these methods. Means for measuring the gases emitted from the waste are described along with laboratory experiments designed to gain more information regarding rates of generation, species of gases emitted and modes of gas storage and release. Finally, the process for closing the USQ is outlined as are the information requirements to understand and resolve the flammable gas issue.

Johnson, G.D.

1997-01-29

361

Selected Topics in Surface Electromyography for Use in the Occupational Setting: Expert Perspectives.  

National Technical Information Service (NTIS)

The various chapters in the compilation discuss surface electromyography as it can be applied to ergonomic studies. Topics include aspects associated with the use of electromyography for the study of ergonomic problems; the anatomic and physiologic inform...

1992-01-01

362

A Survey for the Collection of Professional Opinion on Selected Fire Protection Engineering Topics.  

National Technical Information Service (NTIS)

A survey questionnaire on selected fire protection engineering topics was sent to 422 persons from every state and major city in the United States and, parts of Canada. Those surveyed included architects, engineers, insurance and government representative...

G. A. Harrison J. L. Houser

1975-01-01

363

Food supply modifies the trade-off between past and future reproduction in a sexual parasite–host system ( Rana esculenta, Rana lessonae )  

Microsoft Academic Search

Life history theory is concerned with the costs of survival, growth and reproduction under different ecological conditions\\u000a and the allocation of resources to meet these costs. Typical approaches used to address these topics include manipulation\\u000a of food resources, followed by measures of subsequent reproductive traits, and measures of the relationship between current\\u000a and future reproductive investment. Rarely, however, do studies

Marc Olivier Waelti; Heinz-Ulrich Reyer

2007-01-01

364

Contact dermatitis due to topical drugs.  

PubMed

The management of patients who have developed a contact dermatitis due to topical drugs requires to stop the suspected drug application, to treat the patient with corticosteroid ointments, to perform dermatoallergological investigations e.g. drug patch tests in case of contact eczema and diluted prick tests in case of contact urticaria in order to determine whether the adverse drug reaction was due to excipients or to the drug itself. Patients with chronic leg ulcers have a high risk of contact dermatitis to topical drugs and to antiseptics. It is necessary to advise the patient concerning the avoidance of topical but also systemic readministration of the responsible molecule. An excipient responsible in inducing a contact sensitization to a topical drug can also be found in cosmetics, the name of the responsible excipient has to be given to the patient under the common name but also under the INCI name. In most of the cases there is no risk in systemically administering iodine, sulfites or vehicles in a sensitized patient who had developed a contact dermatitis to topical medications. When the drug itself is responsible in inducing a contact allergy it is necessary to determine if cross reactions with other drugs can occur and if the responsible molecule can induce systemic cutaneous adverse drug reactions if the drug is systemically readministered. Among NSAID there is no cross reactions between bufexamac and diclofenac, between salicylamide, glycol salicylate, salicylic acid and acetylsalicylic acid. In case of photosensitization 1) to ketoprofen or 2) piroxicam the topical and/or systemic administration of the following molecules are contraindicated with respectively 1) ketoprofen, tiaprofenic acid, fenofibrate, oxybenzone or 2) piroxicam, thimerosal. A patient sensitized to corticosteroid ointment has to be tested in order to determine which corticosteroid classes are sensitizing. The topical and systemic administrations of molecules belonging to the sensitizing classes (A, B, C, D1 or D2) have to be forbidden. PMID:19834431

Barbaud, A

2009-10-01

365

Introduction to "Tsunamis in the World Ocean: Past, Present, and Future. Volume II"  

NASA Astrophysics Data System (ADS)

Fifteen papers are included in Volume 2 of a PAGEOPH topical issue Tsunamis in the World Ocean: Past, Present, and Future. These papers are briefly introduced. They are grouped into three categories: reports and studies of recent tsunamis, studies on tsunami statistics and application to tsunami warning, and modeling studies of tsunami runup and inundation. Most of the papers were presented at the 24th International Tsunami Symposium held 14-16 July 2009 in Novosibirsk, Russia, and reflect the current state of tsunami science.

Satake, Kenji; Rabinovich, Alexander; Kâno?lu, Utku; Tinti, Stefano

2011-11-01

366

Introduction to "Tsunamis in the World Ocean: Past, Present, and Future. Volume I"  

NASA Astrophysics Data System (ADS)

Eighteen papers are included in Volume 1 of a PAGEOPH topical issue Tsunamis in the World Ocean: Past, Present, and Future. These papers are briefly introduced. They are grouped into three categories: case studies of earthquake-generated tsunamis; tsunami forecast and hazard assessments; and theoretical and computational modeling of tsunami generation, propagation, and coastal behavior. Most of the papers were presented at the 24th International Tsunami Symposium held 14-16 July 2009 in Novosibirsk, Russia, and reflect the current state of tsunami science.

Satake, Kenji; Rabinovich, Alexander; Kâno?lu, Utku; Tinti, Stefano

2011-06-01

367

A View on Future Building System Modeling and Simulation  

SciTech Connect

This chapter presents what a future environment for building system modeling and simulation may look like. As buildings continue to require increased performance and better comfort, their energy and control systems are becoming more integrated and complex. We therefore focus in this chapter on the modeling, simulation and analysis of building energy and control systems. Such systems can be classified as heterogeneous systems because they involve multiple domains, such as thermodynamics, fluid dynamics, heat and mass transfer, electrical systems, control systems and communication systems. Also, they typically involve multiple temporal and spatial scales, and their evolution can be described by coupled differential equations, discrete equations and events. Modeling and simulating such systems requires a higher level of abstraction and modularisation to manage the increased complexity compared to what is used in today's building simulation programs. Therefore, the trend towards more integrated building systems is likely to be a driving force for changing the status quo of today's building simulation programs. Thischapter discusses evolving modeling requirements and outlines a path toward a future environment for modeling and simulation of heterogeneous building systems.A range of topics that would require many additional pages of discussion has been omitted. Examples include computational fluid dynamics for air and particle flow in and around buildings, people movement, daylight simulation, uncertainty propagation and optimisation methods for building design and controls. For different discussions and perspectives on the future of building modeling and simulation, we refer to Sahlin (2000), Augenbroe (2001) and Malkawi and Augenbroe (2004).

Wetter, Michael

2011-04-01

368

Evidence for Future Cognition in Animals  

ERIC Educational Resources Information Center

|Evidence concerning the possibility of mental time travel into the future by animals was reviewed. Both experimental laboratory studies and field observations were considered. Paradigms for the study of future anticipation and planning included inhibition of consumption of current food contingent on future receipt of either a larger quantity or…

Roberts, William A.

2012-01-01

369

Basic Science for a Secure Energy Future  

NASA Astrophysics Data System (ADS)

Anticipating a doubling in the world's energy use by the year 2050 coupled with an increasing focus on clean energy technologies, there is a national imperative for new energy technologies and improved energy efficiency. The Department of Energy's Office of Basic Energy Sciences (BES) supports fundamental research that provides the foundations for new energy technologies and supports DOE missions in energy, environment, and national security. The research crosses the full spectrum of materials and chemical sciences, as well as aspects of biosciences and geosciences, with a focus on understanding, predicting, and ultimately controlling matter and energy at electronic, atomic, and molecular levels. In addition, BES is the home for national user facilities for x-ray, neutron, nanoscale sciences, and electron beam characterization that serve over 10,000 users annually. To provide a strategic focus for these programs, BES has held a series of ``Basic Research Needs'' workshops on a number of energy topics over the past 6 years. These workshops have defined a number of research priorities in areas related to renewable, fossil, and nuclear energy -- as well as cross-cutting scientific grand challenges. These directions have helped to define the research for the recently established Energy Frontier Research Centers (EFRCs) and are foundational for the newly announced Energy Innovation Hubs. This overview will review the current BES research portfolio, including the EFRCs and user facilities, will highlight past research that has had an impact on energy technologies, and will discuss future directions as defined through the BES workshops and research opportunities.

Horton, Linda

2010-03-01

370

Including Conflict in Creative Writing.  

ERIC Educational Resources Information Center

|Conflict is the basis of all stories and thus should appear in some form in the first sentence. There are three kinds of conflict: people vs. people; people vs. nature; and people vs. themselves. Conflict must be repeated in all the various elements of the story's structure, including the plot, which is the plan of action telling what happens to…

Litvin, Martin

371

Learning topic models by belief propagation.  

PubMed

Latent Dirichlet allocation (LDA) is an important hierarchical Bayesian model for probabilistic topic modeling, which attracts worldwide interest and touches on many important applications in text mining, computer vision and computational biology. This paper represents the collapsed LDA as a factor graph, which enables the classic loopy belief propagation (BP) algorithm for approximate inference and parameter estimation. Although two commonly used approximate inference methods, such as variational Bayes (VB) and collapsed Gibbs sampling (GS), have gained great success in learning LDA, the proposed BP is competitive in both speed and accuracy, as validated by encouraging experimental results on four large-scale document datasets. Furthermore, the BP algorithm has the potential to become a generic scheme for learning variants of LDA-based topic models in the collapsed space. To this end, we show how to learn two typical variants of LDA-based topic models, such as author-topic models (ATM) and relational topic models (RTM), using BP based on the factor graph representations. PMID:23520254

Zeng, Jia; Cheung, William K; Liu, Jiming

2013-05-01

372

The Princeton separator, past and future  

Microsoft Academic Search

Some past research applications of the Princeton separator are reviewed. The future program envisaged includes fundamental beta decay studies, low temperature nuclear orientation and nuclear astrophysics.

R. A. Naumann; F. W. Loeser; R. B. Vogelaar

1992-01-01

373

Systemic effects of topical ophthalmic beta-adrenoceptor antagonists.  

PubMed

Topical ophthalmic beta-adrenoceptor antagonists (beta-blockers) are generally recognized as the treatment of choice in glaucoma management due to favourable efficacy, safety and tolerability. Despite topical ocular administration, beta-blockers are systemically absorbed, in relatively small amounts, through the nasolacrimal drainage system and can adversely affect cardiovascular and pulmonary function. While cardioselective beta-blockers, such as betaxolol, possibly confer an advantage with respect to clinical safety through their receptor affinity, systemic effects are also influenced by other pharmacological factors, including the rate and extent of systemic absorption and the extent of plasma protein binding. These factors are reviewed to distinguish the various ophthalmic beta-blockers and to explain the observed clinical differences in the safety profiles of these medications. PMID:10080340

Rait, J L

1999-02-01

374

Topical azithromycin as a novel treatment for ocular rosacea.  

PubMed

Abstract Purpose: Acne rosacea is a common dermatological conditions associated with blepharitis. Current treatments include artificial tears, lid hygiene, and systemic doxycycline. In this study the authors evaluate the effectiveness of topical azithromycin in ocular rosacea. Methods: The authors enrolled 37 ocular rosacea patients: 12 were treated with systemic doxycycline, 16 with azithromycin eyedrops, and 9 did not receive medical treatments. Ocular signs and symptoms and side effects were evaluated at baseline and at 1-month follow-up. Results: A significant improvement in TF-BUT, meibomian gland plugging, and Oxford score associated with symptom reduction was reported by all patients after 1 month. All treatments were well tolerated, with mild gastro-intestinal symptoms in 33% of the doxycycline group and mild burning after instillation in the azithromycin group. Conclusions: Topical azithromycin may represent an additional treatment for ocular rosacea, with a shorter duration of treatment and absence of gastrointestinal side effects as compared to systemic doxycycline. PMID:23875944

Mantelli, Flavio; Di Zazzo, Antonio; Sacchetti, Marta; Dianzani, Caterina; Lambiase, Alessandro; Bonini, Stefano

2013-07-22

375

Future of PACS  

NASA Astrophysics Data System (ADS)

This paper attempts to forecast tow to five years to understand the future PACS environment and is the result of reviews of literature and interviews with nearly thirty organization sand individuals representing the PACS community. Two to five years was set as a realistic limit to projections although thoughts for the future of digital medical imaging beyond five years are included. The variance in projections even in the short term is significant and any projection beyond five years will be even more uncertain. The organizations that contributed to the interviews include academic centers, the federal government, consultants and vendors of PACS technology. The vendor products span the industry to include capture of images at the modality level, image management and distribution systems, services, and speech recognition. This paper will place the changes that will occur in PACS within the context of the larger changes that are occurring in health care, the practice of image acquisition and interpretation, and information systems. Selected technologies that will influence PACS are reviewed in more depth with a view towards the affect that they will have on PACS and the interpretation of images.

Kirchdoerfer, Richard G.

1997-05-01

376

Future Optical Networks  

NASA Astrophysics Data System (ADS)

This paper presents views on the future of optical networking. A historical look at the emergence of optical networking is first taken, followed by a discussion on the drivers pushing for a new and pervasive network, which is based on photonics and can satisfy the needs of a broadening base of residential, business, and scientific users. Regional plans and targets for optical networking are reviewed to understand which current approaches are judged important. Today, two thrusts are driving separate optical network infrastructure models, namely 1) the need by nations to provide a ubiquitous network infrastructure to support all the future services and telecommunication needs of residential and business users and 2) increasing demands by the scientific community for networks to support their requirements with respect to large-scale data transport and processing. This paper discusses these network models together with the key enabling technologies currently being considered for future implementation, including optical circuit, burst and packet switching, and optical code-division multiplexing. Critical subsystem functionalities are also reviewed. The discussion considers how these separate models might eventually merge to form a global optical network infrastructure.

O'Mahony, Michael J.; Politi, Christina; Klonidis, Dimitrios; Nejabati, Reza; Simeonidou, Dimitra

2006-12-01

377

Portal to the Future  

NASA Astrophysics Data System (ADS)

Museums are a portal connecting us to a deeper understanding of the world in which we live, from our own backyards to the most distant galaxies; an access point to the incredible discoveries we have made about the natural world and a flashpoint for inspiring the next generation of explorers. The Cleveland Museum of Natural History is poised to redefine what a natural history museum can be, offering visitors an opportunity to travel through space and time to explore the origins of our planet, follow the evolution of life on Earth and project into -- and plan for -- the future. The Museum will launch visitors into the future this summer via SmartHome Cleveland -- an extremely energy-efficient "passive house" that will demonstrate the future of green building technology. This unique exhibit is part of a special series of exhibits, programs and workshops on sustainability, including a major exhibit on Climate Change, which will be featured at the Museum this summer and fall.

Gates, Evalyn

2011-04-01

378

Our computerized future  

SciTech Connect

The author discusses the future of computer technology, and its applications in society. The author speculates on future uses of artificial intelligence, computerised telephone systems, and other general issues. He also considers future technology advances such as biochips.

Lecht, C.P.

1982-01-01

379

Perspectives on the future of educational technology  

Microsoft Academic Search

This study was conducted to determine the opinions of a broad-based sample of educational technology professionals and students\\u000a about the future of our field. A nationwide sample of 268 university personnel (faculty members, doctoral students, and master's\\u000a students) and trainers completed a Likert-type survey that contained 30 items covering six topic areas: Educational Technology\\u000a and Learning Theory, Instructional Design Models,

Howard J. Sullivan; Ann R. Igoe; James D. Klein; Elizabeth E. Jones; Wilhelmina C. Savanye

1993-01-01

380

Systemic drug interactions with topical glaucoma medications.  

PubMed

Topically administered ophthalmic medications are capable of attaining clinically important serum concentrations, as evidenced by the variety of systemic side effects they can produce. These drugs are therefore also capable of interacting with other drugs administered orally and intravenously. This is especially important when medications are administered to an elderly population, who are often receiving multiple medications. The Physician's Desk Reference and the United States Pharmacopeia Drug Information directory contain numerous warnings of potential interactions between topical glaucoma medications and systemically administered drugs. Unfortunately, literature supporting such interactions is limited, both in quantity and quality, being anecdotal in many cases. This report summarizes available information regarding the nonocular interactions between topical ophthalmic glaucoma medications and other systemically administered medications. Clinical evidence of these interactions is lacking in many cases. PMID:1980380

Gerber, S L; Cantor, L B; Brater, D C

381

Dynamic characteristics of tweeting and tweet topics  

NASA Astrophysics Data System (ADS)

Twitter, having more than 200 million world users and more than 4 million Korean users, is still growing fast. Because Twitter users can `tweet' about any topic within the 140-character limit, and other users who follow the users and see the tweets can `retweet' them, Twitter is regarded as a new medium of transferring and sharing information. Nevertheless, the propensities of Twitter users to tweet or to retweet still remain unclear. In order to investigate these propensities, we propose a simple model for the dynamics of the total number of tweets about specific topics. We then observe that the topics can be categorized into three kinds according to predictability and sustainability: predictable events, unpredictable events, and sustainable events. Comparing model results with real data, we infer the tweet propensities motivated by external causes as well as retweet propensities.

Kwon, Hyun Woong; Choi, M. Y.; Kim, Ho Sung; Lee, Keumsook

2012-02-01

382

Clearance of invasive melanoma with topical imiquimod.  

PubMed

A 93-year-old woman presented with biopsy-proven invasive melanoma of 2.75 mm depth, arising from a melanoma in situ. Standard treatment of this depth would be an extensive and mutilating excision, which presented a therapeutic dilemma. Imiquimod has the ability to clear melanoma in situ, but its effect on invasive melanoma is unknown. After a thorough discussion with the patient, we decided to attempt to treat the melanoma in situ with topical imiquimod and then excise the smaller invasive component. Following 5 weeks of topical imiquimod therapy, the area where the nodular melanoma had previously been was excised. Histological examination of the excisional specimen revealed no residual melanoma detected. In this case, it appears that 5 weeks of topical imiquimod therapy completely cleared an invasive melanoma of 2.75 mm depth, as well as clearing the component of melanoma in situ. The patient was followed for 14 months with no evidence of recurrence. PMID:23377337

Moon, Summer D; Spencer, James M

2013-01-01

383

Illustrative EDOF topics in Fourier optics  

NASA Astrophysics Data System (ADS)

In this talk we present a series of illustrative topics in Fourier Optics that are proving valuable in the design of EDOF camera systems. They are at the level of final examination problems that have been made solvable by a student or professoi having studied from one of Joseph W. Goodman's books---our tribute for his 75fr year. As time permits, four illustrative topics are l) Electromagnetic waves and Fourier optics;2) The perfect lens; 3) Connection between phase delay and radially varying focal length in an asphere and 4) tailored EDOF designs.

George, Nicholas; Chen, Xi; Chi, Wanli

2011-09-01

384

A neural network approach to topic spotting  

Microsoft Academic Search

This paper presents an application of nonlinear neural\\u000a networks to topic spotting. Neural networks allow us to\\u000a model higher-order interaction between document terms and\\u000a to simultaneously predict multiple topics using shared\\u000a hidden features. In the context of this model, we compare\\u000a two approaches to dimensionality reduction in\\u000a representation: one based on term selection and another\\u000a based on Latent Semantic Indexing

Erik D. Wiener; Jan O. Pedersen; Andreas S. Weigend

1995-01-01

385

Advanced Topics in Control Systems Theory  

NASA Astrophysics Data System (ADS)

Advanced Topics in Control Systems Theory contains selected contributions written by lecturers at the second (annual) Formation d'Automatique de Paris (FAP) (Graduate Control School in Paris). It is addressed to graduate students and researchers in control theory with topics touching on a variety of areas of interest to the control community such as cascaded systems, flatness, optimal control, and Hamiltonian and infinite-dimensional systems. The reader is provided with a well-integrated synthesis of the latest thinking in these subjects without the need for an exhaustive literature review.

Lamnabhi-Lagarrigue, Françoise; Loría, Antonio; Panteley, Elena

386

Advanced Topics in Control Systems Theory  

NASA Astrophysics Data System (ADS)

Advanced Topics in Control Systems Theory contains selected contributions written by lecturers at the third (annual) Formation d'Automatique de Paris (FAP) (Graduate Control School in Paris). Following on from the lecture notes from the second FAP (Volume 311 in the same series) it is addressed to graduate students and researchers in control theory with topics touching on a variety of areas of interest to the control community such as nonlinear optimal control, observer design, stability analysis and structural properties of linear systems.

Lorsa, Antonio; Lamnabhi-Lagarrigue, Françoise; Panteley, Elena

387

Resource Letter AFHEP-1: Accelerators for the Future of High-Energy Physics  

NASA Astrophysics Data System (ADS)

This Resource Letter provides a guide to literature concerning the development of accelerators for the future of high-energy physics. Research articles, books, and Internet resources are cited for the following topics: motivation for future accelerators, present accelerators for high-energy physics, possible future machine, and laboratory and collaboration websites.

Barletta, William A.

2012-02-01

388

Topics and Sources of Memorable Breast Cancer Messages and Their Impact on Prevention and Detection Behaviors  

PubMed Central

Often, people are able to recall a message on a particular topic for a long period of time. These memorable messages have the ability to influence behavior when they are recalled from memory long after initial exposure. Knowing the topics and sources of the messages that are remembered about breast cancer can improve the efficacy of future breast cancer outreach. To this end, 359 women completed an online survey about memorable breast cancer messages. Most women (60%) recalled a memorable message, described it, identified its source, and noted whether it had resulted in prevention or detection behaviors. Four categories of message topics emerged: early detection (37.3%), awareness (30.9%), treatment (25.8%), and prevention (6%)). Furthermore, five categories of sources of these memorable messages were found: (media (35.5%), friends (22.2%), family (21.6%), medical professionals (15.2%), and others (5.5%)). The media were a major source of all four topics of messages although family members, friends, and the medical community were major sources for particular message topics, as well. Memorable messages originating from medical professionals were substantially more likely to motivate detection behaviors than prevention behaviors. This research demonstrates that message topic and source both play roles in determining message recall as well as in determining how memorable messages impacted behavior.

2009-01-01

389

Education Program on Fossil Resources Including Coal  

NASA Astrophysics Data System (ADS)

Fossil fuels including coal play a key role as crucial energies in contributing to economic development in Asia. On the other hand, its limited quantity and the environmental problems causing from its usage have become a serious global issue and a countermeasure to solve such problems is very much demanded. Along with the pursuit of sustainable development, environmentally-friendly use of highly efficient fossil resources should be therefore, accompanied. Kyushu-university?s sophisticated research through long years of accumulated experience on the fossil resources and environmental sectors together with the advanced large-scale commercial and empirical equipments will enable us to foster cooperative research and provide internship program for the future researchers. Then, this program is executed as a consignment business from the Ministry of Economy, Trade and Industry from 2007 fiscal year to 2009 fiscal year. The lecture that uses the textbooks developed by this program is scheduled to be started a course in fiscal year 2010.

Usami, Masahiro

390

Intelligent building sourcebook. [Glossary included  

SciTech Connect

The intelligent building sourcebook examines exciting new technologies which make it possible to integrate building automation systems (BAS), telecommunications, and office automation systems. This reference demonstrates how to apply BAS to maximize the comfort of the occupants of a building while minimizing the energy used by the building's heating, ventilating and air conditioning (HVAC) equipment. This fully integrated type of system can also be used to achieve economical, efficient lighting. Other system functions discussed include automated security and fire protection, and computerized building maintenance management. State-of-the-art telecommunication systems incorporating digital PBX are also covered. Building design issues and trends are reviewed, as are the methods of implementing shared tenant services. Technical aspects of building wiring, including both structural and functional integration, are covered in detail. A comprehensive series of case studies of intelligent buildings which have been developed to meet a variety of user requirements round out the book. Most of the 30 chapters have been abstracted separately for inclusion on the Energy Data Base.

Bernaden, J.A.; Neubauer, R.E. (eds.)

1988-01-01

391

Neoclassical transport including collisional nonlinearity.  

PubMed

In the standard ?f theory of neoclassical transport, the zeroth-order (Maxwellian) solution is obtained analytically via the solution of a nonlinear equation. The first-order correction ?f is subsequently computed as the solution of a linear, inhomogeneous equation that includes the linearized Fokker-Planck collision operator. This equation admits analytic solutions only in extreme asymptotic limits (banana, plateau, Pfirsch-Schlüter), and so must be solved numerically for realistic plasma parameters. Recently, numerical codes have appeared which attempt to compute the total distribution f more accurately than in the standard ordering by retaining some nonlinear terms related to finite-orbit width, while simultaneously reusing some form of the linearized collision operator. In this work we show that higher-order corrections to the distribution function may be unphysical if collisional nonlinearities are ignored. PMID:21770513

Candy, J; Belli, E A

2011-06-10

392

Neoclassical Transport Including Collisional Nonlinearity  

SciTech Connect

In the standard {delta}f theory of neoclassical transport, the zeroth-order (Maxwellian) solution is obtained analytically via the solution of a nonlinear equation. The first-order correction {delta}f is subsequently computed as the solution of a linear, inhomogeneous equation that includes the linearized Fokker-Planck collision operator. This equation admits analytic solutions only in extreme asymptotic limits (banana, plateau, Pfirsch-Schlueter), and so must be solved numerically for realistic plasma parameters. Recently, numerical codes have appeared which attempt to compute the total distribution f more accurately than in the standard ordering by retaining some nonlinear terms related to finite-orbit width, while simultaneously reusing some form of the linearized collision operator. In this work we show that higher-order corrections to the distribution function may be unphysical if collisional nonlinearities are ignored.

Candy, J.; Belli, E. A. [General Atomics, P.O. Box 85608, San Diego, California 92186-5608 (United States)

2011-06-10

393

Interview "Problems" as Topics for Analysis  

ERIC Educational Resources Information Center

In this article the author argues that interactional difficulties and questioning practices identified in the methodological literature on qualitative interviewing as "problems" provide topics of analysis. Methodological examinations of interview data drawing on conversation analysis also explicate how interview "problems" may be conceptualized in…

Roulston, Kathryn

2011-01-01

394

Illustrative EDOF topics in Fourier optics  

Microsoft Academic Search

In this talk we present a series of illustrative topics in Fourier Optics that are proving valuable in the design of EDOF camera systems. They are at the level of final examination problems that have been made solvable by a student or professoi having studied from one of Joseph W. Goodman's books---our tribute for his 75fr year. As time permits,

Nicholas George; Xi Chen; Wanli Chi

2011-01-01

395

Hot topics in flavor physics at CDF  

SciTech Connect

Hot topics in flavor physics at CDF are reviewed. Selected results of top, beauty, charm physics and exotic states in about 200 pb{sup -1} data collected by the CDF II detector in p{bar p} collisions at {radical}s = 1.96 TeV at the Fermilab Tevatron are presented.

Jun, Soon Yung; /Carnegie Mellon U.

2005-01-01

396

Topical Antimicrobials for Burn Wound Infections  

PubMed Central

Throughout most of history, serious burns occupying a large percentage of body surface area were an almost certain death sentence because of subsequent infection. A number of factors such as disruption of the skin barrier, ready availability of bacterial nutrients in the burn milieu, destruction of the vascular supply to the burned skin, and systemic disturbances lead to immunosuppression combined together to make burns particularly susceptible to infection. In the 20th century the introduction of antibiotic and antifungal drugs, the use of topical antimicrobials that could be applied to burns, and widespread adoption of early excision and grafting all helped to dramatically increase survival. However the relentless increase in microbial resistance to antibiotics and other antimicrobials has led to a renewed search for alternative approaches to prevent and combat burn infections. This review will cover patented strategies that have been issued or filed with regard to new topical agents, preparations, and methods of combating burn infections. Animal models that are used in preclinical studies are discussed. Various silver preparations (nanocrystalline and slow release) are the mainstay of many approaches but antimicrobial peptides, topical photodynamic therapy, chitosan preparations, new iodine delivery formulations, phage therapy and natural products such as honey and essential oils have all been tested. This active area of research will continue to provide new topical antimicrobials for burns that will battle against growing multi-drug resistance.

Dai, Tianhong; Huang, Ying-Ying; Sharma, Sulbha K.; Hashmi, Javad T.; Kurup, Divya B.; Hamblin, Michael R.

2010-01-01

397

Topics in conformally compact Einstein metrics  

Microsoft Academic Search

We discuss a number of topics in the area of conformally compact Einstein\\u000ametrics, mostly centered around the global existence question of finding such\\u000ametrics with an arbitrarily prescribed conformal infinity. The paper is partly\\u000aa survey of this area but also presents new results and a number of open\\u000aproblems.

Michael T. Anderson

2005-01-01

398

It's Elementary: Special Topics in Elementary Education.  

ERIC Educational Resources Information Center

|As elementary teachers work to educate and meet the needs of the students in their care, their job has become increasingly challenging and demanding. This volume addresses a variety of issues and topics related to elementary education around eight sectional themes relevant to the work of elementary teachers: celebrating diversity, classroom…

Crawford, Patricia A., Ed.; Burriss, Kathleen Glascott, Ed.

399

Topic in Depth - The Physics of Sports  

NSDL National Science Digital Library

This topic in depth provides information about the relationship between physics and sports. From baseball to scuba diving, find out how concepts such as velocity, Newton's Laws, and mass factor into the science of sports. Think about this next time you see a home run or a touchdown pass!

2010-09-10

400

Note on Topical N-Grams.  

National Technical Information Service (NTIS)

Most of the popular topic models (such as Latent Dirichlet Allocation) have an underlying assumption: bag of words. However, text is indeed a sequence of discrete word tokens, and without considering the order of words (in another word, the nearby context...

X. Wang A. McCallum

2005-01-01

401

Strategy of topical vaccination with nanoparticles  

Microsoft Academic Search

Liposomes in the nanosize range have been recognized as a versatile drug delivery system of both hydrophilic and lipophilic molecules. In order to develop a liposome-based topical vaccination strategy, five different types of liposomes were tested as a putative vaccine delivery system on pig ear skin. The investigated liposomes mainly varied in size, lipid composition, and surface charge. Using hydrophilic

Sascha Jung; Alexa Patzelt; Nina Otberg; Gisela Thiede; Wolfram Sterry; Juergen Lademann

2009-01-01

402

Simple Semantics in Topic Detection and Tracking  

Microsoft Academic Search

Topic Detection and Tracking (TDT) is a research initiative that aims at techniques to organize news documents in terms of news events. We propose a method that incorporates simple semantics into TDT by splitting the term space into groups of terms that have the meaning of the same type. Such a group can be associated with an external ontology. This

Juha Makkonen; Helena Ahonen-Myka; Marko Salmenkivi

2004-01-01

403

Hungarian topics in Zach's German journals  

Microsoft Academic Search

Two hundred years ago geography and astronomy were very close branches of science. The great task of the era was the determination of exact geographical positions, and astronomical methods were widely used for it. In the volumes of Allgemeine Geographische Ephemeriden (AGE) and in the Monatliche Correspondenz (MC) a large proportion of the Hungarian topics also deal with the geography

László Patkós

1998-01-01

404

Improving recommendation lists through topic diversification  

Microsoft Academic Search

In this work we present topic diversification, a novel method designed to balance and diversify personalized recommendation lists in order to reflect the user's complete spectrum of interests. Though being detrimental to average accuracy, we show that our method improves user satisfaction with recommendation lists, in particular for lists generated using the common item-based collaborative filtering algorithm.Our work builds upon

Cai-Nicolas Ziegler; Sean M. McNee; Joseph A. Konstan; Georg Lausen

2005-01-01

405

Alternative Approaches to Traditional Topics in Algebra  

ERIC Educational Resources Information Center

|Students who otherwise seem unreachable through traditional approaches to algebra require some alternative teaching methods. So do teachers who seek to add elements of freshness and innovation to their classrooms or who simply appreciate variety. This article offers some unconventional techniques for teaching a few conventional algebra topics.…

Coburn, John W.

2010-01-01

406

Topics in the Nez Perce Verb  

ERIC Educational Resources Information Center

|This dissertation investigates several topics in the morphology, syntax and semantics of the Nez Perce verb and verbal clause. The first part of the dissertation focuses on the morphological segmentation of the Nez Perce verb and on the semantic description of the verb and clause. Chapter 1 provides a grammar sketch. Chapter 2 discusses the…

Deal, Amy Rose

2010-01-01

407

Bibliography of Nonparametric Statistics and Related Topics  

Microsoft Academic Search

This bibliography contains 999 references on nonparametric statistics and related topics, classified as follows: (A) Surveys and Discussions (39), (B) Theory (31), (C) Tchebycheff Inequalities (94), (D) Tolerance Sets (21), (E) Goodness of Fit (122), (F) Multisample Problems (53), (G) Parameter Problems (135), (H) Contingency Tables (75), (I) Randomness (109), (J) Correlation and Curve Fitting (96), (K) Comparative Studies (49),

I. Richard Savage

1953-01-01

408

Interview "Problems" as Topics for Analysis  

ERIC Educational Resources Information Center

|In this article the author argues that interactional difficulties and questioning practices identified in the methodological literature on qualitative interviewing as "problems" provide topics of analysis. Methodological examinations of interview data drawing on conversation analysis also explicate how interview "problems" may be conceptualized…

Roulston, Kathryn

2011-01-01

409

Topics in physico-chemical hydrodynamics  

SciTech Connect

This paper discusses the following topics: theory of turbulent flame speed; flame extinction by periodic flow-field; influence of swirl on the structure and extinction of premixed flames; propagation and extinction of nonsteady spherical flame fronts; geometrically invariant formulation of intrinsic dynamics of premixed flames; nonlinear dynamics of oscillatory regime of premixed combustion; and pattern formation in premixed flames. (LSP)

Sivashinsky, G.

1989-01-01

410

The sequence of topics in beginners' psychology  

Microsoft Academic Search

Presents the manner of approach and sequence of topics as they exist in introductory text-books and in beginners' classes of psychology. The conventional rubrics have been employed but the data lack definiteness, since the familiar terminology has widely different connotations for different writers and teachers. Hence consideration has been taken to indicate the relative position in the text-book order. It

L. W. Sackett

1915-01-01

411

Parent-Teen Communication about Sexual Topics.  

ERIC Educational Resources Information Center

|Examines parent-teen communication about sexual topics in mother-teen (n=666) and father-teen (n=510) pairs. Results show that, aside from gender of parents and teens, demographic variables were insignificant; relationship and attitudinal variables were linked to sexual discussions in both mother-teen and father-teen dyads. (Author/MKA)|

Raffaelli, Marcela; Bogenschneider, Karen; Flood, Mary Fran

1998-01-01

412

Legal research topics within services sciences  

Microsoft Academic Search

The paper presents a study to define some of the most important legal topics that need to be in- cluded in the Services Sciences' research agenda. To analyze what sort of legal challenges the forthcoming services will have, an example of advanced service framework, MobiLife Service Framework, is presented. The framework high- lights especially challenges in privacy and data protection

Olli Pitkänen

2006-01-01

413

From term variants to research topics  

Microsoft Academic Search

In a science and technology watch (STW) task, an expert user needs to survey the evolution of research topics in his area of specialisation in order to detect interesting changes. The majority of methods proposing evaluation metrics (bibliometrics and scientometrics studies) for STW rely solely on statistical data analysis methods (co-citation analysis, co-word analysis). Such methods usually work on structured

Fidelia Ibekwe-SanJuan

414

Tinea nigra: successful treatment with topical butenafine*  

PubMed Central

The authors report a case of Tinea nigra in an 8-year-old child, male, from Itajaí, SC, Brazil, with lesions of the macular hyperchromic type, unique, asymptomatic, localized in the right palmar area. The lesion was treated with the topical antifungal butenafine, with remission of symptoms and without recurrence at follow-up for two years.

Rossetto, Andre Luiz; Cruz, Rosana Ce Bella

2012-01-01

415

Popularization of Chemistry through Ecological Topics.  

ERIC Educational Resources Information Center

|After providing information on elementary schooling in Yugoslavia, discusses ecological topics and activities used to raise the awareness of elementary school students about the level of pollution in the environment and the dangers of an increasingly polluted environment. Students' keen interest in chemistry and the chemical experiments was…

Perina, I.

1982-01-01

416

Topics in Cosmology and Particle Physics.  

National Technical Information Service (NTIS)

In these three lectures, some of the major topics are reviewed which concern both particle physics and cosmology. In the first lecture, a general overview of the standard cosmological Big Bang model is given, and Big Bang nucleosynthesis is briefly gone o...

K. A. Olive

1985-01-01

417

Teaching Mathematical Trade Topics for Conceptual Understanding.  

ERIC Educational Resources Information Center

This book is intended to assist trade and industrial education teachers in teaching mathematical trade topics in a way that will increase students' conceptual understanding of them. The first chapter provides an overview of the book's contents and suggests ways of using it. The next five chapters address the following aspects of using principles…

Larkin, Alan; Phillips, Keith

418

Quantitative Topics in Research on Aging  

Microsoft Academic Search

The origins of the present series of articles on quantitative topics in aging research are presented. Specific articles are described, the purposes and goals of the quantitative series are set forth, and the relationship of this body of knowledge to the scientific status of the area of aging research is discussed.

J. J. Mcardle; Stanley A. Cohen

1991-01-01

419

Topical Use of Dexpanthenol in Skin Disorders  

Microsoft Academic Search

Pantothenic acid is essential to normal epithelial function. It is a component of coenzyme A, which serves as a cofactor for a variety of enzyme-catalyzed reactions that are important in the metabolism of carbohydrates, fatty acids, proteins, gluconeogenesis, sterols, steroid hormones, and porphyrins. The topical use of dex- panthenol, the stable alcoholic analog of pantothenic acid, is based on good

Fritz Ebner; Andreas Heller; Frank Rippke; Irene Tausch

2002-01-01

420

Allergic contact dermatitis from topical corticosteroid preparations  

Microsoft Academic Search

Background: Allergic reactions to corticosteroids have been frequently reported from Europe since 1986. Screening with markers of steroid allergy such as tixocortol privalate and testing with steroids in ethanol have accounted for most of the reports. Since adding tixocortol to the standard tray in 1992, we also have noted an increase in topical steroid allergy.Objective: The purpose of this article

Linda J. Jagodzinski; James S. Taylor; Howard Oriba

1995-01-01

421

Topical treatment options for conjunctival neoplasms  

PubMed Central

Topical therapies offer a nonsurgical method for treating conjunctival tumors by delivering high drug concentrations to the ocular surface. Over the past ten years, topical agents have been used by investigators to treat various premalignant and malignant lesions of the conjunctiva, such as primary acquired melanosis with atypia, conjunctival melanoma, squamous intraepithelial neoplasia and squamous cell carcinoma of the conjunctiva, and pagetoid spread of the conjunctiva arising from sebaceous cell carcinoma. Despite the enthusiasm generated by the success of these agents, there are unanswered questions regarding the clinical efficacy of this new nonsurgical approach, and whether a single topical agent can achieve cure rates comparable with traditional therapies. Furthermore, the long-term consequences of prolonged courses of topical chemotherapeutic drugs on the ocular surface are unknown, and the ideal regimen for each of these agents is still being refined. In this review, we present specific guidelines for treating both melanocytic and squamous neoplasms of the conjunctiva, utilizing the available data in the literature as well as our own clinical experience at the Memorial Sloan-Kettering Cancer Center.

Kim, Jonathan W; Abramson, David H

2008-01-01

422

Topic in Depth - Harvesting the Rain  

NSDL National Science Digital Library

Rain harvesting has experienced a bit of a renaissance in recent years through the promotion and installation of rain gardens and rain barrels. These water collection mechanisms help to curb erosion and the spread of pollution; conserve precious freshwater; and support water-loving plants. This Topic in Depth presents websites and electronic publications containing instructive and descriptive information about rain gardens and barrels.

2010-09-03

423

Linking clinical data using XML topic maps  

Microsoft Academic Search

Most clinical data is narrative text and often not accessible and searchable at the clinical workstation. We have therefore developed a search engine that allows indexing, searching and linking different kinds of data using web technologies. Text matching methods fail to represent implicit relationships between data, e.g. the relationship between HIV and AIDS. The international organization for standardization (ISO) topic

Ralf Schweiger; Simon Hoelzer; Dirk Rudolf; Joerg Rieger; Joachim Dudeck

2003-01-01

424

[Off-label indications for topical tacrolimus].  

PubMed

The topical calcineurin antagonist tacrolimus plays an important role in the treatment of different forms of eczema because of its favorable risk profile. In addition, different off-label indications have been clinically tested where tacrolimus ointment has achieved clinical improvement. This article discusses off-label treatment of vitiligo, seborrheic dermatitis, steroid rosacea, perioral dermatitis, rosacea and lichen sclerosus. PMID:24150824

Hengge, U R

2013-10-01

425

Anaphylaxis to topically applied sodium fusidate.  

PubMed

Fusidic acid is a bacteriostatic antibiotic that is effective primarily on gram-positive bacteria, such as Staphylococcus and Corynebacterium species. It is often topically applied to the skin, but is also given systemically as a tablet or injection. Allergic contact dermatitis, or urticaria, has been reported as a side effect of fusidic acid treatment, whereas anaphylaxis to topically administered fusidic acid has not been reported previously. A 16-year-old boy visited an outpatient clinic for further evaluation of anaphylaxis. He suffered abrasions on his arms during exercise, which were treated with a topical ointment containing sodium fusidate. Within 30 minutes, he developed urticaria and eyelid swelling, followed by a cough and respiratory difficulty. His symptoms were relieved by emergency treatment in a nearby hospital. To investigate the etiology, oral provocation with fusidate was performed. After 125 mg (1/2 tablet) of sodium fusidate was administered, he developed a cough and itching of the throat within 30 minutes, which was followed by chest discomfort and urticaria. Forced expiratory volume in 1 second (FEV1) dropped from 4.09 L at baseline to 3.50 L after challenge, although wheezing was not heard in his chest. After management with an inhaled bronchodilator using a nebulizer, chest discomfort was relieved and FEV1 rose to 3.86 L. The patient was directed not to use fusidate, especially on abrasions. Here we report the first case of anaphylaxis resulting from topical fusidic acid application to abrasions. PMID:23450038

Park, Mi-Ran; Kim, Do-Soo; Kim, Jihyun; Ahn, Kangmo

2012-11-02

426

Benchmark Dose Modeling - Advanced Topics Course  

EPA Science Inventory

Benchmark Dose Modeling – Advanced Topics Course The objectives of this full-day course are to provide participants with training on how to use the U.S. Environmental Protection Agency’s (EPA) Benchmark Dose Modeling Software (BMDS) and related software programs to fa...

427

Angola: a great future  

SciTech Connect

The companies represented in Angola and their concessions by area are tabulated, including offshore leases. The government of this only recently independent country puts great emphasis on petroleum development and welcomes foreign companies. The major portion of the production comes from the fields in the Cabinda area. In the future, the reserves in the Congo basin will become more important. Exploration activity is intense and concentrated on the near offshore area of the country. The gas reserves are still not entirely known; present production serves only the needs of petroleum production, including a gas injection project in the Cabinda area and the production of LPG. A map of the offshore concession blocks also is shown.

Not Available

1980-11-01

428

Energy strategies: Toward a solar future  

Microsoft Academic Search

The book includes an assessment of energy requirements, nonrenewable and renewable energy resources, energy storage and transmission, and projections of energy demands. Topics also covered include coal gasification, oil shale, nuclear fission generators, geothermal energy, solar heating and cooling, photovoltaic cells, wind generators, biomass to gas conversion, ocean thermal energy, and wave energy extraction.

H. W. Kendall; S. J. Nadis

1980-01-01

429

Compatibility of a protein topical gel with wound dressings.  

PubMed

The compatibility between several dressing materials and a recombinant human vascular endothelial growth factor (rhVEGF) topical methylcellulose gel formulation was investigated. The dressings being studied were Adaptic, Non-stick Dressing, Conformant 2, Opsite and Tegapore. The criteria to select a compatible dressing include protein stability, absence of leachables from the dressing, and ability to retain gel on wound. An LC-MS method with sample treatment using cellulase was developed to determine protein oxidation in gel formulations. Results showed that rhVEGF was significantly oxidized by Adaptic dressing in 24 h. Protein oxidation was likely due to the peroxides, as determined by FOX assay, released into the protein solution from the dressing. Furthermore, Adaptic dressing caused protein adsorption loss, formation of high MW protein adducts, and released leachables as determined by RP-HPLC, LC-MS, and SEC. No protein oxidation or loss was observed after exposure to the other four alternative dressings. However, unknown leachables were detected in the presence of Opsite and Non-stick Dressing. The pore sizes of the Conformant 2 and Non-stick dressings were too large to hold the topical gel within the wound area, making them unsuitable for patient use. No rhVEGF bioactivity loss was observed in the presence of Tegapore. In conclusion, Tegapore was considered suitable for the rhVEGF topical gel. PMID:18623201

Ji, Junyan A; Borisov, Oleg; Ingham, Erika; Ling, Victor; Wang, Y John

2009-02-01

430

Future Sources of Polarised Positrons  

SciTech Connect

Polarised positrons have a range of applications in modern physics: from surface science measurements requiring energies as low as a few eV, to studies of the proton structure function and of the fundamental interactions of elementary particles at energies approaching the TeV scale. The common challenge for all of these studies is to generate sufficient numbers of positrons. A discussion of this topic is pertinent to these proceedings as it has been suggested that anti-protons can be efficiently polarised through a hyperfine spin-flip interaction with polarised positrons. In this paper I review the current state of high-intensity sources of polarised positrons. Emphasis is placed on those sources being developed to meet the requirements of future e{sup +} e{sup -} colliders.

Bailey, I. R. [Cockcroft Institute, Daresbury Laboratory, Warrington, WA4 4AD (United Kingdom) Department of Physics, University of Liverpool, Liverpool, L69 7ZE (United Kingdom)

2008-04-30

431

Four Cases of Facial Discoid Lupus Erythematosus Successfully Treated with Topical Pimecrolimus or Tacrolimus  

PubMed Central

Discoid lupus erythematosus (DLE), which is a cutaneous form of lupus erythematosus (LE), is generally refractory to a wide range of topical or systemic therapies. Although the main treatment option for DLE is topical steroids, it is often ineffective or likely to produce long-term side effects. New drugs, including tacrolimus and pimecrolimus, have been developed to overcome the adverse effects of steroids and treat the lesions of DLE for a prolonged period. We herein report 4 cases of facial DLE successfully treated with therapeutic adjuvants, topical tacrolimus or pimecrolimus.

Han, Ye Won; Kim, Hyung Ok; Park, Sung Hwan

2010-01-01

432

A Model to Assess the Effectiveness of Topical Antipruritics  

Microsoft Academic Search

A model has been developed to determine the effectiveness of topical antipruritics. It utilizes controlled, experimentally induced itch and has demonstrated the effectiveness of the direct action on cutaneous receptor sites of a topical anesthetic, benzocaine, in a topical antipruritic formulation, and has been used to differentiate between two effective topical antipruritics. Three studies are presented: The first study examined

Ronald Drozdenko; Stephen C. Pennisi; Wilfred Minkin; Howard Spivak; Sidney Weinstein; Curt Weinstein

1996-01-01

433

Topic Detection Of Unrestricted Texts: Approaches And Evaluations  

Microsoft Academic Search

Topic detection and tracking refers to automatic techniques for locating topically related cohesive paragraphs in a stream of text. Most documents are about more than one subject, but many Natural Language Processing (NLP) and Information Retrieval (IR) techniques implicitly assume documents have just one topic. Even in the presence of a single topic within a document, the document may address

Yllias Chali

2005-01-01

434

Discrepancies among Teachers' Priorities for and Knowledge of Freshwater Topics.  

ERIC Educational Resources Information Center

|Teachers were asked to examine a list of water topics, assign a level of priority for their students to know about each topic, then report on their own knowledge level and the amount of teaching they do on the topics. Indicates that topics such as basic water properties and wetlands that had high priorities among teachers were not accompanied by…

Fortner, Rosanne W.; Meyer, Richard L.

2000-01-01

435

Gender representation in illustrations, text, and topic areas in sexuality education curricula.  

PubMed

A content analysis instrument was developed to examine differences in gender representation in sexuality education curricula. Fourteen middle school and high school curricula, published between 1985 and 1995, were examined. Variables included illustrations, noun/pronoun usage, and specific topics within the two categories of biological function and mutual interest. The study examined differences in gender representation in illustrations, photographs, cartoons, drawings, and text. Omission of sexuality topics related to gender also was examined. Little difference occurred within the text of the curricula in noun and pronoun usage. Illustrations were few in number, but showed greater female representation. Greater male representation occurred in topics related to drug use, sexual exploitation, sexual desire, and homosexuality. Topics with greater female representation included body image, diseases of the reproductive organs, and hygiene. PMID:8981265

Beyer, C E; Ogletree, R J; Ritzel, D O; Drolet, J C; Gilbert, S L; Brown, D

1996-12-01

436

Nuclear Futures Analysis and Scenario Building  

Microsoft Academic Search

This LDRD project created and used advanced analysis capabilities to postulate scenarios and identify issues, externalities, and technologies associated with future ''things nuclear''. ''Things nuclear'' include areas pertaining to nuclear weapons, nuclear materials, and nuclear energy, examined in the context of future domestic and international environments. Analysis tools development included adaptation and expansion of energy, environmental, and economics (E3) models

E. D. Arthur; D. Beller; G. H. Canavan; R. A. Krakowski; P. Peterson; R. L. Wagner

1999-01-01

437

Eprinomectin: A novel avermectin for use as a topical endectocide for cattle  

Microsoft Academic Search

Eprinomectin (MK-397 or 4?-epi-acetylamino-4?-deoxy-avermectin B1) is a novel avermectin selected for development as a topical endectocide for all cattle, including lactating dairy cows. Herein, we show its anthelmintic, insecticidal and miticidal activity. To determine its anthelmintic capabilities, eprinomectin was tested topically on Jersey calves at 0.08, 0.2, or 0.5 mg kg?1 in a probe formulation against experimental infections of adult

W. L. Shoop; J. R. Egerton; C. H. Eary; H. W. Haines; B. F. Michael; H. Mrozik; P. Eskola; M. H. Fisher; L. Slayton; D. A. Ostlind; B. J. Skelly; R. K. Fulton; D. Barth; S. Costa; L. M. Gregory; W. C. Campbell; R. L. Seward; M. J. Turner

1996-01-01

438

Efficacy and Safety of Topically Applied Tacrolimus Ointment in Patients with Moderate to Severe Atopic Dermatitis  

Microsoft Academic Search

Background: Tacrolimus is a T-cell-selective cytokine inhibitor. The topical formulation was specifically developed for treating inflammatory skin diseases, including atopic dermatitis (AD). The purpose of this study was to evaluate the effica- cy and safety of topically applied tacrolimus ointment (Protopic®) in treating Taiwanese patients with moderate to severe AD. Methods: This was an open-labeled, non-comparative, single-center study. Enrolled patients

Wen-Rou Wong; Hsiang-Ju Tsai; Hong-Shang Hong

439

Immunomodulatory Therapy in Ophthalmology – Is There a Place for Topical Application?  

Microsoft Academic Search

Topical corticosteroids, although effective in the treatment of ocular immune-mediated diseases, are well known for their ocular side-effects. Not surprisingly, a variety of alternative immunomodulatory agents have been tested for topical use including cyclosporin A (CsA), mycophenolate mofetil (MMF), tacrolimus (FK506), rapamycin (sirolimus) and leflunomide. Local application bears the possibility to avoid the severe side-effects of systemic therapy. The effect

Eckart Bertelmann; Uwe Pleyer

2004-01-01

440

A review of the use of topical analgesics for myofascial pain  

Microsoft Academic Search

Numerous treatment strategies for myofascial pain syndrome are available, including physical therapy, behavioral pain management\\u000a techniques, acupuncture, various types of injections, and the use of various pharmacotherapeutic approaches. The use of topical\\u000a analgesics for myofascial pain syndrome is the focus of this review. The use of topical analgesics in other painful states\\u000a is also reviewed.

Charles E. Argoff

2002-01-01

441

Selected Topics on Hadronic B Decays From BaBar  

SciTech Connect

Recent measurements of branching fractions and decay-rate asymmetries in charmless hadronic B decays at the BaBar experiment are presented. The selected topics include Dalitz plot analyses of B {yields} K{sup +} {pi}{sup -}{pi} and signal searches in B {yields} PP and PV, where isoscalar mesons are involved, and in B {yields} b{sub 1}P, P and V denote a pseudoscalar and vector meson, respectively. Several measurements in charmless hadronic B decays have indicated possible deviations from the theoretical predictions within the Standard Model. The measurements presented would contribute to searching for and resolving such puzzles.

Suzuki, K.; /SLAC

2011-11-23

442

The Community of the Future. The Drucker Foundation Future Series.  

ERIC Educational Resources Information Center

|This book is a collection of 25 essays that explore what communities will look like in the future. They include: "Introduction: Civilizing the City" (Peter F. Drucker); (1) "The Paradox and Promise of Community" (Margaret J. Wheatley and Myron Kellner-Rogers); (2) "Economic Community and Social Investment" (Lester C. Thurow); (3) "The…

Hesselbein, Frances, Ed.; Goldsmith, Marshall, Ed.; Beckhard, Richard, Ed.; Schubert, Richard F., Ed.

443

The Community of the Future. The Drucker Foundation Future Series.  

ERIC Educational Resources Information Center

This book is a collection of 25 essays that explore what communities will look like in the future. They include: "Introduction: Civilizing the City" (Peter F. Drucker); (1) "The Paradox and Promise of Community" (Margaret J. Wheatley and Myron Kellner-Rogers); (2) "Economic Community and Social Investment" (Lester C. Thurow); (3) "The…

Hesselbein, Frances, Ed.; Goldsmith, Marshall, Ed.; Beckhard, Richard, Ed.; Schubert, Richard F., Ed.

444

Aged Care in the Future and Baby Boomers: Shall the Twain Ever Meet?  

Microsoft Academic Search

Background: The ageing of baby boomers may create significant financial strain upon aged and community care in the future. Topic and Objectives: In this literature review, we examine why concern has been expressed about Australia's ability to cope with the \\

Anthony Bruce Fallon; Kay Price; Desley Hegney; Jennifer Abbey; Christine Neville; Deborah Oxlade; Jeffrey Soar

445

Physical Review Special Topics: Physics Education Research  

NSDL National Science Digital Library

How do people learn about physics? It's an important topic, especially as many countries seek to train a new generation of physicists. The Physical Review Special Topics: Physics Education Research (PRST-PER) journal is committed to providing high quality research on the teaching and learning of physics. Visitors can scan through the journal's newer articles via Recent Papers, where they will find works like "Development and implications of technology in reform-based physics laboratories" and "What do students do when asked to diagnose their mistakes? Does it help them?" There are several hundred articles which visitors can scan through at their leisure or search by keyword. Finally, users can take a tour through the News, Announcements, and Editorials section of the site to learn about new site features and updates from the American Physics Society.

2012-10-16

446

Investigation of some topical formulations containing dexpanthenol.  

PubMed

Owing to its ability to regenerate epidermal cells Dexpanthenol (D-panthenol; chemically known as (+)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide) has found use for the treatment of patholytic ileus and postoperative distention. The purpose of research was to develop a gel containing dexpanthenol by monitoring the effect of various concentrations of a gelating agent on the activity of the ciliary apparatus. A system containing 2.5% of hydroxyethylcellulose was optimal for the preparation of the gel. Together with a formulation containing 5% of dexpanthenol, drops with equal concentration of the active compound were tested for comparison. Physical characteristics, such as osmotic pressure, acidity, density and viscosity of the preparation were determined as well as its microbiological sterility. The anti-inflammatory activity of the gel was determined following its topical application. Epidermal tests showed its good tolerance after topical application to the shaved skin of guinea pigs. PMID:15794335

Stozkowska, Wies?awa; Pieko?, Ryszard

447

[Topical application of TNF-blockers].  

PubMed

In 1998, the first TNF-blocker was approved in the USA and a year later in Germany. Treatment with TNF-blocking agents has significantly expanded therapeutic options for patients with chronic inflammatory diseases in rheumatology, dermatology and gastroenterology. However, it is not always possible to achieve a local clinical improvement by systemically administered TNF-blockers. Many approaches to topical therapy with TNF blockers have been published in recent years. The main objective of these off-label applications is the injection of a larger quantity of TNF-blocker in the inflamed tissue than it is achievable with systemic therapy. This summary provides an overview of the variety of topical therapy trials and reports own experiences in patients with Crohn's disease. PMID:23404327

Teich, N

2013-02-12

448

Topical proparacaine abuse resulting in evisceration.  

PubMed

A 72-year-old man was admitted to our clinic because of pain in the right eye. Corneal oedema, peripheral anterior synechiae formation and intraocular lens were determined in the right eye. The left eye was normal except for nuclear sclerosis. Intraocular pressure was 35 mm Hg in the right eye and 14 mm Hg in the left eye. The patient was diagnosed as having bullous keratopathy and glaucoma. He was treated with antiglaucoma drugs and artificial tears as an outpatient. Persistent keratopathy was observed at follow-up, despite adequate therapy. In the detailed anamnesis of the patient, we discovered that he had used a topical anaesthetic instead of the prescribed medicine owing to ocular pain. The patient was still using topical anaesthetic eye drops, despite warnings. Finally, evisceration was performed on his right eye because of corneal melting and perforation. PMID:23608875

Aksoy, Adnan; Ba?kan, Ahmet Metin; Aslan, Lokman; Aslankurt, Murat

2013-04-22

449

Of possible cheminformatics futures.  

PubMed

For over a decade, cheminformatics has contributed to a wide array of scientific tasks from analytical chemistry and biochemistry to pharmacology and drug discovery; and although its contributions to decision making are recognized, the challenge is how it would contribute to faster development of novel, better products. Here we address the future of cheminformatics with primary focus on innovation. Cheminformatics developers often need to choose between "mainstream" (i.e., accepted, expected) and novel, leading-edge tools, with an increasing trend for open science. Possible futures for cheminformatics include the worst case scenario (lack of funding, no creative usage), as well as the best case scenario (complete integration, from systems biology to virtual physiology). As "-omics" technologies advance, and computer hardware improves, compounds will no longer be profiled at the molecular level, but also in terms of genetic and clinical effects. Among potentially novel tools, we anticipate machine learning models based on free text processing, an increased performance in environmental cheminformatics, significant decision-making support, as well as the emergence of robot scientists conducting automated drug discovery research. Furthermore, cheminformatics is anticipated to expand the frontiers of knowledge and evolve in an open-ended, extensible manner, allowing us to explore multiple research scenarios in order to avoid epistemological "local information minimum trap". PMID:22207193

Oprea, Tudor I; Taboureau, Olivier; Bologa, Cristian G

2011-12-30

450

[Antibiotics: present and future].  

PubMed

The author discuss the up to date interpretation of the concept of antibiotics and antibiotic research, as well as the present role of various natural, semisynthetic and synthetic antibiotic compounds in various areas of the human therapy. The origin and the total number of all antibiotics and applied antibiotics in the practice, as well as the bioactive microbial metabolites (antibiotics) in other therapeutical, non-antibiotic fields (including agriculture) are also reviewed. The author discusses main problems, such as increasing (poly)resistance, virulence of pathogens and the non-scientific factors (such as a decline of research efforts and their sociological, economic, financial and regulatory reasons). A short summary of the history of Hungarian antibiotic research is also provided. The author briefly discusses the prospects in the future and the general advantages of the natural products over synthetic compounds. It is concluded that new approaches for the investigation of the unlimited possibilities of the living world are necessary. The discovery of new types or simply neglected (micro)organisms and their biosynthetic capabilities, the introduction of new biotechnological and genetic methods (genomics, metagenom, genome mining) are absolutely required in the future. PMID:23567874

Bérdy, János

2013-04-14

451

Fueling the Future with Fungal Genomics  

SciTech Connect

Fungi play important roles across the range of current and future biofuel production processes. From crop/feedstock health to plant biomass saccharification, enzyme production to bioprocesses for producing ethanol, higher alcohols or future hydrocarbon biofuels, fungi are involved. Research and development are underway to understand the underlying biological processes and improve them to make bioenergy production efficient on an industrial scale. Genomics is the foundation of the systems biology approach that is being used to accelerate the research and development efforts across the spectrum of topic areas that impact biofuels production. In this review, we discuss past, current and future advances made possible by genomic analyses of the fungi that impact plant/feedstock health, degradation of lignocellulosic biomass and fermentation of sugars to ethanol, hydrocarbon biofuels and renewable chemicals.

Grigoriev, Igor V.; Cullen, Daniel; Hibbett, David; Goodwin, Stephen B.; Jeffries, Thomas W.; Kubicek, Christian P.; Kuske, Cheryl; Magnuson, Jon K.; Martin, Francis; Spatafora, Joey; Tsang, Adrian; Baker, Scott E.

2011-04-29

452

Topics in two-dimensional string theory  

Microsoft Academic Search

We explore various topics in two-dimensional string theory. Firstly, we study particle production in time-dependent backgrounds of the c = 1 matrix model, a holographic description of bosonic string theory in 1+1 dimensions. The process is described most efficiently in terms of anomalies, but we also discuss the explicit mode expansions. In matrix cosmology the usual vacuum ambiguity of quantum

Joshua L. Davis

2006-01-01

453

From term variants to research topics  

Microsoft Academic Search

Abstract In a science and technology watch (STW) task, an expert user needs to survey the evolution of research topics in his area of specialisation in order to detect interesting changes. The majority ofmethods,proposing evaluation metrics (bibliometrics and scientometrics studies) for STW rely solely on statistical data analysis methods (co-citation analysis, co-word analysis). Such methods usually work on structured databases

F Bekwe-sanjuan; E Sanjuan

2002-01-01

454

Topical compositions comprising benfotiamine and pyridoxamine  

US Patent & Trademark Office Database

The present invention provides a composition comprising an effective amount of benfotiamine and an effective amount of pyridoxamine in a suitable vehicle for topical application. The present compositions are useful in improving the appearance of aged skin characterized by wrinkles, loss of elasticity, and hyperpigmentation caused by chronoaging and/or photoaging of skin, by inhibiting particularly skin damage resulting from reactive carbonyl species (RCS), glycation of skin proteins, formation of advanced glycation endproducts (AGEs) and formation of advanced lipoxidation endproducts (ALEs).

2010-02-23

455

Topical cannabinoid antinociception: synergy with spinal sites  

Microsoft Academic Search

Analgesic effects of cannabimimetic compounds have been known to be related to their central effects. Cannabinoid receptors also exist in the periphery but their role in pain perception has been remained to be clarified. Therefore, we assessed topical antinociceptive effects of WIN 55, 212-2, a mixed CB1 and CB2 receptors agonist, in mice using tail-flick test. Immersion of the tail

Ahmet Dogrul; Husamettin Gul; Ahmet Akar; Oguzhan Yildiz; Ferruh Bilgin; Erdal Guzeldemir

2003-01-01

456

Recent topics of micro and nano mechatronics  

Microsoft Academic Search

This paper focuses on the recent topics of micro and nano mechatronics. A nano laboratory-a prototype nano manufacturing system based on nanorobotlic manipulation-is presented for enabling nanotube-based micro- and nano- mechatronics, such as microhano sensors and actuators, bio- applications and nano-robotics applications. Deflection of cantilevered individual nanotubes based mass flow sensors, field emission of a cantilevered nanotube based approaching sensor,

Toshio Fukuda; Fumihito Arai; Lixin Dong; Y. Imaizumi

2004-01-01

457

Topic Brief 4: Above-Code Buildings  

SciTech Connect

The American Recovery and Reinvestment Act (ARRA) requires a plan for achieving compliance with building energy codes in at least 90% of the new and renovated residential and commercial building space. The Department of Energy's (DOE's) Building Energy Codes Program (BECP) is developing procedures and tools for measuring compliance as required in this legislation. This is the fourth topic brief, to be posted on the BECP website, responding to feedback received on these procedures.

Connell, Linda M.

2009-10-07

458

Topical Ketoconazole for Infantile Seborrhoeic Dermatitis  

Microsoft Academic Search

In an open study, 19 infants with a bipolar seborrhoeic rash were treated with ketoconazole 2% in cream once a day and evaluated over 10 days of treatment. At day 10, 78.9% of patients were almost cleared. Percutaneous absorption peaked 1–3 h after topical treatment, and was minimal. No plasma ketoconazole accumulation over the 10-day treatment was detected. Treatment failures

A. Taieb; V. Legrain; C. Palmier; S. Lejean; J. Maleville

1990-01-01

459

Hot topics in international emergency medicine.  

PubMed

The Global Burden of Disease report published in 1996 predicted that by 2020 the majority of illness burden globally will be from in-juries, mental illness, and chronic diseases. Patients with many of the disorders leading the list frequently require emergent care. This article provides a brief literature-based introduction to these and other important topics relevant to international development of emergency medicine. PMID:15663974

Arnold, L Kristian; Fernandez, William G; Altman, R Scott

2005-02-01

460

How to improve the design of the electrical system in future wind power plants  

Microsoft Academic Search

HIS paper presents three topics which are important for better performance of future wind farms. The topics are investigated in three coordinated Ph.D. projects ongoing at the Technical University of Denmark (DTU), Aalborg University (AAU) and DONG Energy. The objective of all projects is to improve the understanding of the main electrical components in wind farms, based on available information,

I. Arana; L. Kocewiak; J. Holbřll; C. L. Bak; A. H. Nielsen; A. Jensen; J. Hjerrild; T. Sřrensen

461

The Global Evidence Mapping Initiative: Scoping research in broad topic areas  

Microsoft Academic Search

Background  Evidence mapping describes the quantity, design and characteristics of research in broad topic areas, in contrast to systematic\\u000a reviews, which usually address narrowly-focused research questions. The breadth of evidence mapping helps to identify evidence\\u000a gaps, and may guide future research efforts. The Global Evidence Mapping (GEM) Initiative was established in 2007 to create\\u000a evidence maps providing an overview of existing

Peter Bragge; Ornella Clavisi; Tari Turner; Emma Tavender; Alex Collie; Russell L Gruen

2011-01-01

462

Tracking Multiple Topics for Finding Interesting Articles  

SciTech Connect

We introduce multiple topic tracking (MTT) for iScore to better recommend news articles for users with multiple interests and to address changes in user interests over time. As an extension of the basic Rocchio algorithm, traditional topic detection and tracking, and single-pass clustering, MTT maintains multiple interest profiles to identify interesting articles for a specific user given user-feedback. Focusing on only interesting topics enables iScore to discard useless profiles to address changes in user interests and to achieve a balance between resource consumption and classification accuracy. iScore is able to achieve higher quality results than traditional methods such as the Rocchio algorithm. We identify several operating parameters that work well for MTT. Using the same parameters, we show that MTT alone yields high quality results for recommending interesting articles from several corpora. The inclusion of MTT improves iScore's performance by 25% in recommending news articles from the Yahoo! News RSS feeds and the TREC11 adaptive filter article collection. And through a small user study, we show that iScore can still perform well when only provided with little user feedback.

Pon, R K; Cardenas, A F; Buttler, D J; Critchlow, T J

2008-01-03

463

Topic models: A novel method for modeling couple and family text data  

PubMed Central

Couple and family researchers often collect open-ended linguistic data – either through free response questionnaire items or transcripts of interviews or therapy sessions. Because participant's responses are not forced into a set number of categories, text-based data can be very rich and revealing of psychological processes. At the same time it is highly unstructured and challenging to analyze. Within family psychology analyzing text data typically means applying a coding system, which can quantify text data but also has several limitations, including the time needed for coding, difficulties with inter-rater reliability, and defining a priori what should be coded. The current article presents an alternative method for analyzing text data called topic models (Steyvers & Griffiths, 2006), which has not yet been applied within couple and family psychology. Topic models have similarities with factor analysis and cluster analysis in that topic models identify underlying clusters of words with semantic similarities (i.e., the “topics”). In the present article, a non-technical introduction to topic models is provided, highlighting how these models can be used for text exploration and indexing (e.g., quickly locating text passages that share semantic meaning) and how output from topic models can be used to predict behavioral codes or other types of outcomes. Throughout the article a collection of transcripts from a large couple therapy trial (Christensen et al., 2004) is used as example data to highlight potential applications. Practical resources for learning more about topic models and how to apply them are discussed.

Atkins, David C.; Rubin, Tim N.; Steyvers, Mark; Doeden, Michelle A.; Baucom, Brian R.; Christensen, Andrew

2012-01-01

464

Topics in quantum cryptography, quantum error correction, and channel simulation  

NASA Astrophysics Data System (ADS)

In this thesis, we mainly investigate four different topics: efficiently implementable codes for quantum key expansion [51], quantum error-correcting codes based on privacy amplification [48], private classical capacity of quantum channels [44], and classical channel simulation with quantum side information [49, 50]. For the first topic, we propose an efficiently implementable quantum key expansion protocol, capable of increasing the size of a pre-shared secret key by a constant factor. Previously, the Shor-Preskill proof [64] of the security of the Bennett-Brassard 1984 (BB84) [6] quantum key distribution protocol relied on the theoretical existence of good classical error-correcting codes with the "dual-containing" property. But the explicit and efficiently decodable construction of such codes is unknown. We show that we can lift the dual-containing constraint by employing the non-dual-containing codes with excellent performance and efficient decoding algorithms. For the second topic, we propose a construction of Calderbank-Shor-Steane (CSS) [19, 68] quantum error-correcting codes, which are originally based on pairs of mutually dual-containing classical codes, by combining a classical code with a two-universal hash function. We show, using the results of Renner and Koenig [57], that the communication rates of such codes approach the hashing bound on tensor powers of Pauli channels in the limit of large block-length. For the third topic, we prove a regularized formula for the secret key assisted capacity region of a quantum channel for transmitting private classical information. This result parallels the work of Devetak on entanglement assisted quantum communication capacity. This formula provides a new family protocol, the private father protocol, under the resource inequality framework that includes the private classical communication without the assisted secret keys as a child protocol. For the fourth topic, we study and solve the problem of classical channel simulation with quantum side information at the receiver. Our main theorem has two important corollaries: rate-distortion theory with quantum side information and common randomness distillation. Simple proofs of achievability of classical multi-terminal source coding problems can be made via a unified approach using the channel simulation theorem as building blocks. The fully quantum generalization of the problem is also conjectured with outer and inner bounds on the achievable rate pairs.

Luo, Zhicheng

465

The Future of Clinical Dentistry.  

ERIC Educational Resources Information Center

|Discussion of the future of clinical dentistry looks at a variety of influences, including historical development factors; demographic trends; the role of the Human Genome Project in the development of scientific knowledge; a paradigm shift in approaches to oral infection and systemic disease; advancing technology; and reforms resulting from…

Slavkin, Harold C.

1998-01-01

466

Present Vision--Future Vision.  

ERIC Educational Resources Information Center

|This paper addresses issues of current and future technology use for and by individuals with visual impairments and blindness in Florida. Present technology applications used in vision programs in Florida are individually described, including video enlarging, speech output, large inkprint, braille print, paperless braille, and tactual output…

Fitterman, L. Jeffrey

467

The Future of the Universe.  

ERIC Educational Resources Information Center

|The future of the universe is discussed in terms of several models. These include the closed, open, and critical models of the universe. Black holes and speculation on what may happen to life in the cosmological models are also discussed. (JN)|

Page, Don N.; McKee, M. Randall

1983-01-01

468

The Future of Clinical Dentistry.  

ERIC Educational Resources Information Center

Discussion of the future of clinical dentistry looks at a variety of influences, including historical development factors; demographic trends; the role of the Human Genome Project in the development of scientific knowledge; a paradigm shift in approaches to oral infection and systemic disease; advancing technology; and reforms resulting from these…

Slavkin, Harold C.

1998-01-01

469

Future Directions in Computer Use.  

ERIC Educational Resources Information Center

|Trends that may impact future uses of the computer in speech-language pathology and audiology are addressed. These include broadened training applications, development of cross-platform computers, hardware and software developments in speech processing and recognition and in expert systems, and developments in telecommunications and distance…

Masterson, Julie J.

1995-01-01

470

TOPICAL REVIEW: Multifunctional nanoassemblies of block copolymers for future cancer therapy  

NASA Astrophysics Data System (ADS)

Nanoassemblies from amphiphilic block copolymers are promising nanomedicine platforms for cancer diagnosis and therapy due to their relatively small size, high loading capacity of drugs, controlled drug release, in vivo stability and prolonged blood circulation. Recent clinical trials with self-assembled polymeric micelles incorporating anticancer drugs have shown improved antitumor activity and decreased side effects encouraging the further development of nanoassemblies for drug delivery. This review summarizes recent approaches considering stimuli-responsive, multifunctionality and more advanced architectures, such as vesicles or worm-like micelles, for tumor-specific drug and gene delivery.

Cabral, Horacio; Kataoka, Kazunori

2010-02-01

471

Gap analysis methodology for identifying future ICT related eGovernment research topics - case of \\  

Microsoft Academic Search

Modern ICT enables governments all over the world to improve their operation in order to become more efficient and effective. Despite of all possible benefits of using modern ICT, governments still struggle with the problems of inefficiency of their operation. eGovernment is being discussed in many contexts. Expectations of research and implementation in this field were high. However, many investments

Andreja Pucihar; Kristina Bogataj; Maria Wimmer

472

Future technical directions  

NASA Astrophysics Data System (ADS)

The areas of more recent technical advances are discussed. These are necessarily limited to those areas approved for public dissemination. The presentation is organized as follows: new directions in the Space Shuttle Main Engine (SSME); Computational Fluid Dynamics (CFD) advances; and other areas of technology advances. The advances in the SSME are focused on the continued support to reliable flights with additional benefits in lower cost and improved robustness. In the area of CFD, significant advances are made and emphasis is placed on further reductions in time and cost to perform the complex CFD in product design organizations. The need to better understand and analyze the reality of the environments and products that are designed are discussed. This includes emphasis on dynamic loads; probabilistic as well as deterministic loads, material properties, and hardware variations; and such real property effects as the existence of flaws. Each area represents significant challenges to the engineer of the future.

Jackson, Eugene D.; Sindir, Munir

473

The future is 'ambient'  

NASA Astrophysics Data System (ADS)

The research field of ambient media starts to spread rapidly and first applications for consumer homes are on the way. Ambient media is the logical continuation of research around media. Media has been evolving from old media (e.g. print media), to integrated presentation in one form (multimedia - or new media), to generating a synthetic world (virtual reality), to the natural environment is the user-interface (ambient media), and will be evolving towards real/synthetic undistinguishable media (bio-media or bio-multimedia). After the IT bubble was bursting, multimedia was lacking a vision of potential future scenarios and applications. Within this research paper the potentials, applications, and market available solutions of mobile ambient multimedia are studied. The different features of ambient mobile multimedia are manifold and include wearable computers, adaptive software, context awareness, ubiquitous computers, middleware, and wireless networks. The paper especially focuses on algorithms and methods that can be utilized to realize modern mobile ambient systems.

Lugmayr, Artur

2006-02-01

474

Predicting the earth's future  

NASA Astrophysics Data System (ADS)

The development of earth system models that will simulate the past and present and provide predictions of future conditions is essential now that human activities have the potential to induce changes in the planetary environment. Critical aspects of global change include its pervasiveness and ubiquity, its distribution in several distinct time-scale bands, and the interactions between the atmosphere, ocean, land surface, and the terrestrial and marine biospheres. A model of the earth system on the scale of decades to centuries, developed by the Earth System Science Committee (NASA) with the strategy of dividing by time scale rather than discipline, is presented and the requirements for observations to support the implementation of the model are reviewed.

Dutton, J. A.

1986-10-01

475

Future of forecasting  

NASA Astrophysics Data System (ADS)

This talk surveyed recent progress in forecasting nonlinear time series, including: the breakdown of linear systems theory, nonlinear generalizations by explicit embedding models and implicit neural network models, the role of geometrical invariants in embedding observations, using embedding to build forecasting models, the connection between high- dimensional entropy and dynamics in characterizing nonlinear systems, extension of embedding to more general linear transformations and to its experimental measurement by time-average expectation values, the difference between long-term modeling and short-term forecasting, and strategies for bringing time into connectionist architectures. The details of these techniques, as well as comparisons of their performance on a range of experimental data sets, is available in Time Series Prediction: Forecasting the Future and Understanding the Past, edited by Andreas Weigend and Neil Gershenfeld, Santa Fe Institute Studies in the Sciences of Complexity, Addison-Wesley, August 1993.

Gershenfeld, Neil

1993-11-01

476

Topical Melatonin for Treatment of Androgenetic Alopecia  

PubMed Central

Background: In the search for alternative agents to oral finasteride and topical minoxidil for the treatment of androgenetic alopecia (AGA), melatonin, a potent antioxidant and growth modulator, was identified as a promising candidate based on in vitro and in vivo studies. Materials and Methods: One pharmacodynamic study on topical application of melatonin and four clinical pre-post studies were performed in patients with androgenetic alopecia or general hair loss and evaluated by standardised questionnaires, TrichoScan, 60-second hair count test and hair pull test. Results: Five clinical studies showed positive effects of a topical melatonin solution in the treatment of AGA in men and women while showing good tolerability: (1) Pharmacodynamics under once-daily topical application in the evening showed no significant influence on endogenous serum melatonin levels. (2) An observational study involving 30 men and women showed a significant reduction in the degree of severity of alopecia after 30 and 90 days (P < 0.001) based on questionnaires completed by investigators and patients. (3) Using a digital software-supported epiluminescence technique (TrichoScan) in 35 men with AGA, after 3 and 6 months in 54.8% to 58.1% of the patients a significant increase of hair density of 29% and 41%, respectively was measured (M0: 123/cm2; M3: 159/cm2; M6: 173/cm2;) (P < 0,001). (4) In 60 men and women with hair loss, a significant reduction in hair loss was observed in women, while hair loss in men remained constant (P < 0.001). (5) In a large, 3-month, multi-center study with more than 1800 volunteers at 200 centers, the percentage of patients with a 2- to 3-fold positive hair-pull test decreased from 61.6% to 7.8%, while the percentage of patients with a negative hair-pull test increased from 12.2.% to 61.5% (P < 0.001). In addition, a decrease in seborrhea and seborrheic dermatitis of the scalp was observed. Conclusions: Since safety and tolerability in all of the studies was good, the topical application of a cosmetic melatonin solution can be considered as a treatment option in androgenetic alopecia.

Fischer, Tobias W; Trueb, Ralph M; Hanggi, Gabriella; Innocenti, Marcello; Elsner, Peter

2012-01-01

477

Making light work: illuminating the future of biomedical optics.  

PubMed

In 1996, the Royal Society held a Discussion Meeting entitled 'Near-infrared spectroscopy and imaging of living systems'. In 2010, this topic was revisited in a Theo Murphy Royal Society Scientific Discussion Meeting entitled 'Making light work: illuminating the future of biomedical optics'. The second meeting provided the opportunity for leading researchers to reflect on how the technology, methods and applications have evolved over the past 14 years and assess where they have made a major impact. Particular emphasis was placed on discussions of future prospects and associated challenges. This Introduction provides an overview of the state of the art of near-infrared spectroscopy (NIRS) and biomedical optics, with specific reference to the contributed papers from the invited speakers included in this issue. Importantly, we also reflect on the contributions from all of the attendees by highlighting the issues raised during oral presentations, facilitated panel sessions and discussions, and use these to summarize the current opinion on the development and application of optical systems for use in the clinical and life sciences. A notable outcome from the meeting was a plan to establish a biennial international conference for developers and users of NIRS technologies. PMID:22006895

Elwell, Clare E; Cooper, Chris E

2011-11-28

478

Aviation in the Future  

ERIC Educational Resources Information Center

|Makes predications concerning future aerospace technology in the areas of supersonic transportation, aircraft design, airfreight, military aviation, hypersonic aircraft and in the much distant future sub-orbital, rocket propelled transports. (BR)|

Kayten, Gerald G.

1974-01-01

479

Renewable Electricity Futures (Presentation)  

SciTech Connect

This presentation library summarizes findings of NREL's Renewable Electricity Futures study, published in June 2012. RE Futures investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050.

Mai, T.

2012-10-01

480

Our Future Donors  

ERIC Educational Resources Information Center

The rhetorical advantages and dangers involved in casting the students as "future donors" are explained. The way in which the institutions have to change for casting its students as future donors is described.

Miller, Richard E.

2004-01-01

481

Renewable Electricity Futures (Presentation)  

SciTech Connect

This presentation summarizes findings of NREL's Renewable Electricity Futures study, published in June 2012. RE Futures investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050.

Hand, M. M.

2012-09-01

482

Renewable Electricity Futures (Presentation)  

SciTech Connect

This presentation summarizes findings of NREL's Renewable Electricity Futures study, published in June 2012. RE Futures investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050.

Mai, T.

2012-11-01

483

Media depictions of health topics: challenge and stigma formats.  

PubMed

This article explored the notion that media depictions of health concerns come in one of two formats: challenge and stigma. After explicating the five features that should appear in challenge format and the seven features of stigma formats, we analyzed the content of health messages in magazines, brochures, and posters (n = 75) in a metropolitan area. The results of a two-factor confirmatory factor model showed that the five suggested features for challenge formats did, indeed, appear together (alpha = .76), and the seven features for stigma formats, also, appeared together (alpha = .90), and showed no residual relationship. In other words, the results suggest that media depictions of health topics appear in either challenge or stigma formats (r = - .87). Health issues appearing in magazine advertisements and articles presented messages in challenge formats, while brochures and posters from largely nonprofit and government groups depicted health issues in stigma formats. Some health topics appeared most often in challenge formats (including cancer, heart disease, and scoliosis), while others appeared in stigma formats (including tuberculosis, hepatitis, smoking, and sexually transmitted diseases [STDs]). Findings suggest that media depictions of health differ, and the implications of stigma and challenge formats are discussed. PMID:17497378

Smith, Rachel

484

Topical anesthetics in children: agents and techniques that equally comfort patients, parents, and clinicians.  

PubMed

Topical anesthetics are increasingly important, as the number of outpatient surgeries for dermatologic problems in infants and children is steadily growing. This noninvasive modality of anesthetic delivery in conjunction with a reassuring environment may minimize the discomfort of otherwise painful procedures. Since the 1880s, when cocaine was first used as a topical ophthalmologic anesthetic, many ester-and amide-based local anesthetics have been developed for a variety of simple and complex procedures. The pediatric dermatologist's arsenal of topical anesthetic preparations is increasing with the development of novel vehicles of transdermal delivery and the use of anesthetics in combination. Eutectic mixture of local anesthetics is currently the most frequently prescribed topical agent, though the use of ELA-max, another lidocaine-containing preparation, is gaining momentum, especially in the neonatal population. Amethocaine, tetracaine, iontophoresis, and the S-caine patch, a product on the horizon for use in the pediatric population, also are included in this discussion. PMID:11717557

Chen, B K; Cunningham, B B

2001-08-01

485

Creating Our Future.  

ERIC Educational Resources Information Center

Three papers are presented: the future society for which we are educating, by Robert Theobold; relationship of state government and higher education in the future, by Patrick Lucey; and the future of manpower, the economy, and higher education, by Willard Wirtz. (MSE)

Society for Coll. and Univ. Planning, Halifax (Nova Scotia).

486

Exploring the Educational Future  

ERIC Educational Resources Information Center

|Futures studies uses scenarios--stories of the future--to explore how trends and events shaping our world may play out in future decades. This article features a short scenario set in California in 2037, depicting twelve-year-old Moya and her brother mart, whose "fenced community" has opted for a system of self-directed, online learning to…

Merritt, Elizabeth E.

2012-01-01

487

Reading the Future  

Microsoft Academic Search

{Excerpt} Scenario-building enables managers to invent and then consider in depth several varied stories of equally plausible futures. They can then make strategic decisions that will be sound for all plausible futures. No matter what future takes place, one is more likely to be ready for and influential in it if one has thought seriously about scenarios. Scenario planning challenges

Olivier Serrat

2008-01-01

488

Greening the Future  

ERIC Educational Resources Information Center

|Because educators vicariously touch the future through their students, the author believes that they sometimes have the uncanny ability to see the future. One common future forecast is the phenomenal growth of green jobs in the emerging green economy, leading to the creation of the "Reach of the Sun" Solar Energy Academy at La Mirada High School…

Williamson, Norma Velia

2011-01-01

489

Pachamama: Our Earth, Our Future  

NSDL National Science Digital Library

This section of the children's page of the United Nations Environmental Programme contains essays, poems, and art by young people from around the globe, with a focus on environmental preservation. In the 'Our Earth' section are works about pollution and problems with deforestation, biodiversity, and urbanization. The second section, 'Our Future', concentrates on what the future holds if no actions are taken. The final section is a call to action and is called 'What We Can Do'. There is also a list of contributors, a glossary, and a maze game that includes an interactive quiz. This material is also available as a book.

490

LTRACK: Beam-transport calculation including wakefield effects  

SciTech Connect

LTRACK is a first-order beam-transport code that includes wakefield effects up to quadrupole modes. This paper will introduce the readers to this computer code by describing the history, the method of calculations, and a brief summary of the input/output information. Future plans for the code will also be described.

Chan, K.C.D.; Cooper, R.K.

1988-01-01

491

Including indirect environmental impacts in waste management planning  

Microsoft Academic Search

Activities within waste management systems, such as energy and material recovery, can lead to indirect environmental impacts that occur outside of waste management systems. In this paper, the effect of including indirect greenhouse-gas emissions on the choice of waste management solutions on a national level is explored. The global warming potentials (GWPs) of future waste management solutions for Sweden are

Maria Ljunggren Söderman

2003-01-01

492

Thyroid nodule guidelines: agreement, disagreement and need for future research  

Microsoft Academic Search

This article reviews agreement, disagreement and need for future research of the thyroid nodule guidelines published by the British Thyroid Association, National Cancer Institute, American Thyroid Association and the joint, transatlantic effort of three large societies, the American Society of Clinical Endocrinologists, Associazione Medici Endocrinologi and the European Thyroid Association, published in 2010. Consensus exists for most topics in the

Laszlo Hegedüs; Erik Alexander; Roberto Valcavi; Enrico Papini; Hossein Gharib; Ralf Paschke

2011-01-01

493

UK and British Gas: Any future for Norwegian gas.  

National Technical Information Service (NTIS)

The paper deals with the UK natural gas market and the future for Norwegian gas in the UK. The role of the British Gas in the domestic and European markets is discussed. Topics are: The UK gas supply market; the UK upstream gas market and the Interconnect...

P. Jungles

1996-01-01

494

Honors Futures Course: Orwell's "1984"--Myth or Reality.  

ERIC Educational Resources Information Center

|An overview is provided of an honors futures course offered at Isothermal Community College and entitled "Orwell's '1984': Myth or Reality." The paper traces the sequence of class activities, discussion topics, and student assignments for the 11-week course. The following issues are discussed, both within and outside of the context of related…

Callahan, Barbara

495

Dare To Dream: A Guide to Planning Your Future. Revised.  

ERIC Educational Resources Information Center

This workbook is intended to help students with disabilities plan their postschool futures. In addition to the general material, "Dare To Know" boxes highlight important information, while "Dare To Think" and "Dare To Do" boxes provide activities to help with planning. Individual sections focus on topics such as the following: planning my…

Webb, Kristine; Repetto, Jeanne; Beutel, Adory; Perkins, Dollean; Bailey, Mary; Schwartz, Stuart

496

The future of religion: Intersections of Rorty, Vattimo and Zabala  

Microsoft Academic Search

The following work builds and expands on a number of critical themes that were raised and discussed in a colloquy initiated by Santiago Zabala on the topic ‘the future of religion’ (which carries the title of the published version) with the American philosopher Richard Rorty and Italian political activist Gianni Vattimo. But, on top of the essay's principal aim, a

Virgilio Aquino Rivas

2008-01-01

497

CALL and the Future of Language Teacher Education  

ERIC Educational Resources Information Center

|Interest in technology in language teacher education has grown recently as evidenced by the success of CALICO's Teacher Education SIG and the publication of two edited volumes on the topic in the past 2 years. Here, I explore the current state of technology and teacher education and suggest that the future paths of language teacher education and…

Hubbard, Philip

2008-01-01

498

The Future of Work: Some Prospects and Perspectives. A Compilation.  

ERIC Educational Resources Information Center

The question of what the future of work in the United States will be is examined in this publication using current information on trends and issues related to work, the economy, and the labor force. The compilation intended to give an overview of selected aspects of the topic and provide information about other resources. In the first section,…

Cho, DaeYeon; Imel, Susan

499

Dare To Dream: A Guide to Planning Your Future. Revised.  

ERIC Educational Resources Information Center

|This workbook is intended to help students with disabilities plan their postschool futures. In addition to the general material, "Dare To Know" boxes highlight important information, while "Dare To Think" and "Dare To Do" boxes provide activities to help with planning. Individual sections focus on topics such as the following: planning my…

Webb, Kristine; Repetto, Jeanne; Beutel, Adory; Perkins, Dollean; Bailey, Mary; Schwartz, Stuart

500

Reshaping the Future of Social Studies: Literature/Research Review.  

ERIC Educational Resources Information Center

This literature/research review was conducted to provide information to guide future work on the Western Canadian Protocol Social Studies K-12 Project and reflects the researchers' perspectives on topics and subjects reviewed. The review represents a broad synthesis of relevant research and literature in the key areas identified, not an exhaustive…

McKay, Roberta; Gibson, Susan