Science.gov

Sample records for gas management options

  1. Evaluating greenhouse gas impacts of organic waste management options using life cycle assessment.

    PubMed

    Kong, Dung; Shan, Jilei; Iacoboni, Mario; Maguin, Stephen R

    2012-08-01

    Efforts to divert organics away from landfills are viewed by many as an important measure to significantly reduce the climate change impacts of municipal solid waste management. However, the actual greenhouse gas (GHG) impacts of organics diversion from landfills have yet to be thoroughly evaluated and whether such a diversion provides significant environmental benefits in terms of GHG impacts must be answered. This study, using California-specific information, aimed to analyse the GHG impacts of organics diversion through a life-cycle assessment (LCA). This LCA considered all aspects of organics management including transportation, materials handling, GHG emissions, landfill gas capture/utilization, energy impacts, and carbon sequestration. The LCA study evaluated overall GHG impacts of landfilling, and alternative management options such as composting and anaerobic digestion for diverted organic waste. The LCA analysis resulted in net GHG reductions of 0.093, 0.048, 0.065 and 0.073 tonnes carbon equivalent per tonne organic waste for landfilling, windrow composting, aerated static pile composting, and anaerobic digestion, respectively. This study confirms that all three options for organics management result in net reductions of GHG emissions, but it also shows that organics landfilling, when well-managed, generates greater GHG reductions. The LCA provides scientific insight with regards to the environmental impacts of organics management options, which should be considered in decision and policy-making. The study also highlights the importance of how site and case-specific conditions influence project outcomes when considering organic waste management options. PMID:22588112

  2. Waste management options to reduce greenhouse gas emissions from paper in Australia

    NASA Astrophysics Data System (ADS)

    Pickin, J. G.; Yuen, S. T. S.; Hennings, H.

    A lifecycle assessment to estimate greenhouse gas emissions in Australia from the paper cycle is summarised. The greenhouse gas emissions from paper in Australia in 1999/2000 were estimated to be 12.1 million tonnes (Mt) of CO 2 equivalent. Nearly half of this amount consisted of CH 4 emissions from landfilled waste paper. Various waste management options were modelled to investigate the greenhouse impact of a tonne of paper over its whole lifecycle. Options that keep paper out of landfills significantly reduce greenhouse emissions, waste-to-energy recovery being most effective. Recycling is also beneficial, and is of particular interest from a management perspective because it can be controlled by the pulp and paper industry. These findings can be extended to other wood-based and organic wastes.

  3. Supply chain management and economic valuation of real options in the natural gas and liquefied natural gas industry

    NASA Astrophysics Data System (ADS)

    Wang, Mulan Xiaofeng

    My dissertation concentrates on several aspects of supply chain management and economic valuation of real options in the natural gas and liquefied natural gas (LNG) industry, including gas pipeline transportations, ocean LNG shipping logistics, and downstream storage. Chapter 1 briefly introduces the natural gas and LNG industries, and the topics studied in this thesis. Chapter 2 studies how to value U.S. natural gas pipeline network transport contracts as real options. It is common for natural gas shippers to value and manage contracts by simple adaptations of financial spread option formulas that do not fully account for the implications of the capacity limits and the network structure that distinguish these contracts. In contrast, we show that these operational features can be fully captured and integrated with financial considerations in a fairly easy and managerially significant manner by a model that combines linear programming and simulation. We derive pathwise estimators for the so called deltas and structurally characterize them. We interpret them in a novel fashion as discounted expectations, under a specific weighing distribution, of the amounts of natural gas to be procured/marketed when optimally using pipeline capacity. Based on the actual prices of traded natural gas futures and basis swaps, we show that an enhanced version of the common approach employed in practice can significantly underestimate the true value of natural gas pipeline network capacity. Our model also exhibits promising financial (delta) hedging performance. Thus, this model emerges as an easy to use and useful tool that natural gas shippers can employ to support their valuation and delta hedging decisions concerning natural gas pipeline network transport capacity contracts. Moreover, the insights that follow from our data analysis have broader significance and implications in terms of the management of real options beyond our specific application. Motivated by current developments

  4. Supply chain management and economic valuation of real options in the natural gas and liquefied natural gas industry

    NASA Astrophysics Data System (ADS)

    Wang, Mulan Xiaofeng

    My dissertation concentrates on several aspects of supply chain management and economic valuation of real options in the natural gas and liquefied natural gas (LNG) industry, including gas pipeline transportations, ocean LNG shipping logistics, and downstream storage. Chapter 1 briefly introduces the natural gas and LNG industries, and the topics studied in this thesis. Chapter 2 studies how to value U.S. natural gas pipeline network transport contracts as real options. It is common for natural gas shippers to value and manage contracts by simple adaptations of financial spread option formulas that do not fully account for the implications of the capacity limits and the network structure that distinguish these contracts. In contrast, we show that these operational features can be fully captured and integrated with financial considerations in a fairly easy and managerially significant manner by a model that combines linear programming and simulation. We derive pathwise estimators for the so called deltas and structurally characterize them. We interpret them in a novel fashion as discounted expectations, under a specific weighing distribution, of the amounts of natural gas to be procured/marketed when optimally using pipeline capacity. Based on the actual prices of traded natural gas futures and basis swaps, we show that an enhanced version of the common approach employed in practice can significantly underestimate the true value of natural gas pipeline network capacity. Our model also exhibits promising financial (delta) hedging performance. Thus, this model emerges as an easy to use and useful tool that natural gas shippers can employ to support their valuation and delta hedging decisions concerning natural gas pipeline network transport capacity contracts. Moreover, the insights that follow from our data analysis have broader significance and implications in terms of the management of real options beyond our specific application. Motivated by current developments

  5. Greenhouse gas emissions of waste management processes and options: A case study.

    PubMed

    de la Barrera, Belen; Hooda, Peter S

    2016-07-01

    Increasing concern about climate change is prompting organisations to mitigate their greenhouse gas emissions. Waste management activities also contribute to greenhouse gas emissions. In the waste management sector, there has been an increasing diversion of waste sent to landfill, with much emphasis on recycling and reuse to prevent emissions. This study evaluates the carbon footprint of the different processes involved in waste management systems, considering the entire waste management stream. Waste management data from the Royal Borough of Kingston upon Thames, London (UK), was used to estimate the carbon footprint for its (Royal Borough of Kingston upon Thames) current source segregation system. Second, modelled full and partial co-mingling scenarios were used to estimate carbon emissions from these proposed waste management approaches. The greenhouse gas emissions from the entire waste management system at Royal Borough of Kingston upon Thames were 12,347 t CO2e for the source-segregated scenario, and 11,907 t CO2e for the partial co-mingled model. These emissions amount to 203.26 kg CO2e t(-1) and 196.02 kg CO2e t(-1) municipal solid waste for source-segregated and partial co-mingled, respectively. The change from a source segregation fleet to a partial co-mingling fleet reduced the emissions, at least partly owing to a change in the number and type of vehicles. PMID:27236164

  6. Mixed waste management options

    SciTech Connect

    Owens, C.B.; Kirner, N.P.

    1991-12-31

    Disposal fees for mixed waste at proposed commercial disposal sites have been estimated to be $15,000 to $40,000 per cubit foot. If such high disposal fees are imposed, generators may be willing to apply extraordinary treatment or regulatory approaches to properly dispose of their mixed waste. This paper explores the feasibility of several waste management scenarios and attempts to answer the question: Can mixed waste be managed out of existence? Existing data on commercially generated mixed waste streams are used to identify the realm of mixed waste known to be generated. Each waste stream is evaluated from both a regulatory and technical perspective in order to convert the waste into a strictly low-level radioactive or a hazardous waste. Alternative regulatory approaches evaluated in this paper include a delisting petition, no migration petition, and a treatability variance. For each waste stream, potentially available treatment options are identified that could lead to these variances. Waste minimization methodology and storage for decay are also considered. Economic feasibility of each option is discussed broadly.

  7. Economic outcomes of greenhouse gas mitigation options

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Economic outcomes of greenhouse gas (GHG) mitigation options are reviewed including reductions in tillage intensity, diversifying crop rotation, and N fertilizer management. The review indicates that, while reducing tillage can be a cost effective GHG mitigation practice, results vary by region and ...

  8. Peak load management: Potential options

    SciTech Connect

    Englin, J.E.; De Steese, J.G.; Schultz, R.W.; Kellogg, M.A.

    1989-10-01

    This report reviews options that may be alternatives to transmission construction (ATT) applicable both generally and at specific locations in the service area of the Bonneville Power Administration (BPA). Some of these options have potential as specific alternatives to the Shelton-Fairmount 230-kV Reinforcement Project, which is the focus of this study. A listing of 31 peak load management (PLM) options is included. Estimated costs and normalized hourly load shapes, corresponding to the respective base load and controlled load cases, are considered for 15 of the above options. A summary page is presented for each of these options, grouped with respect to its applicability in the residential, commercial, industrial, and agricultural sectors. The report contains comments on PLM measures for which load shape management characteristics are not yet available. These comments address the potential relevance of the options and the possible difficulty that may be encountered in characterizing their value should be of interest in this investigation. The report also identifies options that could improve the efficiency of the three customer utility distribution systems supplied by the Shelton-Fairmount Reinforcement Project. Potential cogeneration options in the Olympic Peninsula are also discussed. These discussions focus on the options that appear to be most promising on the Olympic Peninsula. Finally, a short list of options is recommended for investigation in the next phase of this study. 9 refs., 24 tabs.

  9. Environmental assessment of gas management options at the Old Ammässuo landfill (Finland) by means of LCA-modeling (EASEWASTE).

    PubMed

    Manfredi, Simone; Niskanen, Antti; Christensen, Thomas H

    2009-05-01

    The current landfill gas (LFG) management (based on flaring and utilization for heat generation of the collected gas) and three potential future gas management options (LFG flaring, heat generation and combined heat and power generation) for the Old Ammässuo landfill (Espoo, Finland) were evaluated by life-cycle assessment modeling. The evaluation accounts for all resource utilization and emissions to the environment related to the gas generation and management for a life-cycle time horizon of 100 yr. The assessment criteria comprise standard impact categories (global warming, photo-chemical ozone formation, stratospheric ozone depletion, acidification and nutrient enrichment) and toxicity-related impact categories (human toxicity via soil, via water and via air, eco-toxicity in soil and in water chronic). The results of the life-cycle impact assessment show that disperse emissions of LFG from the landfill surface determine the highest potential impacts in terms of global warming, stratospheric ozone depletion, and human toxicity via soil. Conversely, the impact potentials estimated for other categories are numerically-negative when the collected LFG is utilized for energy generation, demonstrating that net environmental savings can be obtained. Such savings are proportional to the amount of gas utilized for energy generation and the gas energy recovery efficiency achieved, which thus have to be regarded as key parameters. As a result, the overall best performance is found for the heat generation option - as it has the highest LFG utilization/energy recovery rates - whereas the worst performance is estimated for the LFG flaring option, as no LFG is here utilized for energy generation. Therefore, to reduce the environmental burdens caused by the current gas management strategy, more LFG should be used for energy generation. This inherently requires a superior LFG capture rate that, in addition, would reduce fugitive emissions of LFG from the landfill surface

  10. Newer Management Options in Leprosy

    PubMed Central

    Rao, P Narasimha; Jain, Suman

    2013-01-01

    Newer management options are needed for leprosy control even at present, as it is predicted that new cases of leprosy will continue to appear for many more years in future. This article detail newer methods of clinical grading of peripheral nerve involvement (thickening, tenderness and nerve pain which are subjective in nature) and the advances made in the use of Ultrasonography and Colour Doppler as an objective imaging tool for nerves in leprosy. It also briefly discusses the newer drugs and alternative regimens as therapeutic management options which hold promise for leprosy in future. PMID:23372204

  11. Managing Nuclear Waste: Options Considered

    SciTech Connect

    DOE

    2002-05-02

    Starting in the 1950s, U.S. scientists began to research ways to manage highly radioactive materials accumulating at power plants and other sites nationwide. Long-term surface storage of these materials poses significant potential health, safety, and environmental risks. Scientists studied a broad range of options for managing spent nuclear fuel and high-level radioactive waste. The options included leaving it where it is, disposing of it in various ways, and making it safer through advanced technologies. International scientific consensus holds that these materials should eventually be disposed of deep underground in what is called a geologic repository. In a recent special report, the National Academy of Sciences summarized the various studies and emphasized that geologic disposal is ultimately necessary.

  12. Greenhouse gas mitigation options for Washington State

    SciTech Connect

    Garcia, N.

    1996-04-01

    President Clinton, in 1993, established a goal for the United States to return emissions of greenhouse gases to 1990 levels by the year 2000. One effort established to help meet this goal was a three part Environmental Protection Agency state grant program. Washington State completed part one of this program with the release of the 1990 greenhouse gas emissions inventory and 2010 projected inventory. This document completes part two by detailing alternative greenhouse gas mitigation options. In part three of the program EPA, working in partnership with the States, may help fund innovative greenhouse gas reduction strategies. The greenhouse gas control options analyzed in this report have a wide range of greenhouse gas reductions, costs, and implementation requirements. In order to select and implement a prudent mix of control strategies, policy makers need to have some notion of the potential change in climate, the consequences of that change and the uncertainties contained therein. By understanding the risks of climate change, policy makers can better balance the use of scarce public resources for concerns that are immediate and present against those that affect future generations. Therefore, prior to analyzing alternative greenhouse gas control measures, this report briefly describes the phenomenon and uncertainties of global climate change, and then projects the likely consequences for Washington state.

  13. New Options in Constipation Management.

    PubMed

    Davis, Mellar; Gamier, Pamela

    2015-12-01

    Constipation is common in the general population and for those on opioids and/or who are suffering from advanced cancer. Self-management consists of dietary changes, exercise, and laxatives. However, responses to self-management efforts are often inadequate to relieve the subjective and objective experience of constipation. Multiple new anti-constipating medications have recently been tested in randomized trials and the following are available commercially: probiotics, prucalopride, lubiprostone, linaclotide, elobixibat, antidepressants, methylnaltrexone, alvimopan, and naloxegol. This review will discuss the evidence-based benefits of these medications and outline an approach to managing constipation. PMID:26449843

  14. Management options in decompensated cirrhosis

    PubMed Central

    Shah, Neeral L; Banaei, Yasmin Pourkazemi; Hojnowski, Kristen L; Cornella, Scott L

    2015-01-01

    Chronic injury to the liver from a variety of different sources can result in irreversible scarring of the liver, known as cirrhosis. Cirrhosis is a major cause of morbidity and mortality in the USA, and according to the Centers for Disease Control and Prevention was responsible for 31,903 deaths in 2010 alone. It is thus of the utmost importance to appropriately manage these patients in the inpatient and outpatient setting to improve morbidity and mortality. In this review, we address four major areas of cirrhosis management: outpatient management of portal hypertension with decompensation, hepatic encephalopathy, hepatorenal syndrome, and bleeding/coagulation issues. Outpatient management covers recommendations for health care maintenance and screening. Hepatic encephalopathy encompasses a brief review of pathophysiology, treatment in the acute setting, and long-term prevention. Hepatorenal syndrome is discussed in regards to pathophysiology and treatment in the hospital setting. Finally, a discussion of the assessment of coagulation profiles in cirrhosis and recommendations for bleeding and thrombosis complications is included. These topics are not all encompassing with regard to this complicated population, but rather an overview of a few medical problems that are commonly encountered in their care. PMID:26203291

  15. Managing diseases in seed garlic: What are the options?

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Organisms (fungi, bacteria, viruses and nematodes) causing diseases of seed garlic are discussed in terms of their pathogenic abilities, aggressiveness, management constraints and management options. Management options for vectors (for viral diseases) are placed in context. Concise and general manag...

  16. Endocrine therapy toxicity: management options.

    PubMed

    Henry, N Lynn

    2014-01-01

    Treatment with adjuvant endocrine therapy, including tamoxifen and the aromatase inhibitors, has resulted in notable improvements in disease-free and overall survival for patients with hormone receptor-positive breast cancer. Despite their proven benefit, however, adherence to and persistence with the medications is poor in part because of bothersome side effects that can negatively affect quality of life. Retrospective analyses have identified possible predictors of development of toxicity. Reports have also suggested that development of toxicity may be a biomarker of better response to therapy. In addition, there has been considerable research investment into the management of these side effects, which may lead to improved adherence and persistence with therapy. However, although notable advances have been made, much more remains to be done to provide patients with truly personalized therapy for hormone receptor-positive breast cancer. PMID:24857109

  17. Selected Energy Management Options for Small Business and Local Government.

    ERIC Educational Resources Information Center

    Wert, Jonathan M.; Worthington, Barry K.

    This document is a checklist of 257 energy management options for small business and local government. The energy management options are categorized under: (1) Energy management strategies; (2) Buildings; (3) Lighting; (4) Water; (5) Waste operations; (6) Equipment; (7) Transportation; and (8) Food preparation. To select options for…

  18. Greenhouse Gas Mitigation Options Database(GMOD)and Tool

    EPA Science Inventory

    Greenhouse Gas Mitigation Options Database (GMOD) is a decision support database and tool that provides cost and performance information for GHG mitigation options for the power, cement, refinery, landfill and pulp and paper sectors. The GMOD includes approximately 450 studies fo...

  19. Therapeutic options for management of endometrial hyperplasia

    PubMed Central

    2016-01-01

    Endometrial hyperplasia (EH) comprises a spectrum of changes in the endometrium ranging from a slightly disordered pattern that exaggerates the alterations seen in the late proliferative phase of the menstrual cycle to irregular, hyperchromatic lesions that are similar to endometrioid adenocarcinoma. Generally, EH is caused by continuous exposure of estrogen unopposed by progesterone, polycystic ovary syndrome, tamoxifen, or hormone replacement therapy. Since it can progress, or often occur coincidentally with endometrial carcinoma, EH is of clinical importance, and the reversion of hyperplasia to normal endometrium represents the key conservative treatment for prevention of the development of adenocarcinoma. Presently, cyclic progestin or hysterectomy constitutes the major treatment option for EH without or with atypia, respectively. However, clinical trials of hormonal therapies and definitive standard treatments remain to be established for the management of EH. Moreover, therapeutic options for EH patients who wish to preserve fertility are challenging and require nonsurgical management. Therefore, future studies should focus on evaluation of new treatment strategies and novel compounds that could simultaneously target pathways involved in the pathogenesis of estradiol-induced EH. Novel therapeutic agents precisely targeting the inhibition of estrogen receptor, growth factor receptors, and signal transduction pathways are likely to constitute an optimal approach for treatment of EH. PMID:26463434

  20. Economics of Alaska North Slope gas utilization options

    SciTech Connect

    Thomas, C.P.; Doughty, T.C.; Hackworth, J.H.; North, W.B.; Robertson, E.P.

    1996-08-01

    The recoverable natural gas available for sale in the developed and known undeveloped fields on the Alaskan North Slope (ANS) total about 26 trillion cubic feet (TCF), including 22 TCF in the Prudhoe Bay Unit (PBU) and 3 TCF in the undeveloped Point Thomson Unit (PTU). No significant commercial use has been made of this large natural gas resource because there are no facilities in place to transport this gas to current markets. To date the economics have not been favorable to support development of a gas transportation system. However, with the declining trend in ANS oil production, interest in development of this huge gas resource is rising, making it important for the U.S. Department of Energy, industry, and the State of Alaska to evaluate and assess the options for development of this vast gas resource. The purpose of this study was to assess whether gas-to-liquids (GTL) conversion technology would be an economic alternative for the development and sale of the large, remote, and currently unmarketable ANS natural gas resource, and to compare the long term economic impact of a GTL conversion option to that of the more frequently discussed natural gas pipeline/liquefied natural gas (LNG) option. The major components of the study are: an assessment of the ANS oil and gas resources; an analysis of conversion and transportation options; a review of natural gas, LNG, and selected oil product markets; and an economic analysis of the LNG and GTL gas sales options based on publicly available input needed for assumptions of the economic variables. Uncertainties in assumptions are evaluated by determining the sensitivity of project economics to changes in baseline economic variables.

  1. Knee osteoarthritis: a review of management options.

    PubMed

    Hussain, S M; Neilly, D W; Baliga, S; Patil, S; Meek, Rmd

    2016-02-01

    Osteoarthritis of the knee is a complex peripheral joint disorder with multiple risk factors. The molecular basis of osteoarthritis has been generally accepted; however, the exact pathogenesis is still not known. Management of patients with osteoarthritis involves a comprehensive history, thorough physical examination and appropriate radiological investigation. The relative slow progress in the disease allows a stepwise algorithmic approach in treatment. Non-surgical treatment involves patient education, lifestyle modification and the use of orthotic devises. These can be achieved in the community. Surgical options include joint sparing procedures such as arthroscopyando osteotomy or joint-replacing procedures. Joint-replacing procedures can be isolated to a single compartment such as patellofemoral arthroplasty or unicompartmental knee replacement or total knee arthroplasty. The key to a successful long-term outcome is optimal patient selection, preoperative counselling and good surgical technique. PMID:27330013

  2. Domestic Options to Offshore Oil and Gas.

    ERIC Educational Resources Information Center

    Kash, Don E.

    1983-01-01

    The continuing controversey over offshore oil/gas has given impetus to searching for domestic energy alternatives. The need for and types of several alternative sources are discussed. Indicates that the United States needs to pursue both offshore and other domestic liquid-fuel sources if it is to avoid becoming increasingly dependent on imports.…

  3. [Current options to manage clopidogrel poor responsiveness].

    PubMed

    Fileti, Luca; Campo, Gianluca; Valgimigli, Marco; Marchesini, Jlenia; Ferrari, Roberto

    2010-12-01

    Antiplatelet therapy (aspirin + clopidogrel) is the cornerstone of treatment for patients with acute coronary syndromes and/or undergoing percutaneous coronary interventions (PCI). More than 40 million patients worldwide receive clopidogrel, but about 20% of them are nonresponders or poor responders. Many studies using different techniques, platelet agonists and definitions have shown that patients who are poor responders to clopidogrel have an increased risk of death, reinfarction and stent thrombosis. The mechanisms leading to poor responsiveness are not fully elucidated and are likely multifactorial: genetic factors, accelerated platelet turnover, up-regulation of the P2Y12 pathways, high baseline platelet reactivity, poor compliance, underdosing and drug-drug interactions. The management of these patients is very difficult, but evidence does exist showing that a strategy of higher maintenance dose or switch to different thienopyridines (e.g. ticlopidine or prasugrel) or use of glycoprotein IIb/IIIa inhibitors during PCI may be helpful to overcome poor responsiveness and improve the long-term clinical outcome. This review describes the impact of poor responsiveness to clopidogrel on clinical outcomes, the mechanisms leading to poor effect, and the different assays to assess it. Finally, current and future options for its management are discussed. PMID:21355335

  4. Use of influence diagrams in gas transfer system option prioritization

    SciTech Connect

    Heger, A.S.; Garcia, M.D.

    1995-08-01

    A formal decision-analysis methodology was applied to aid the Department of Energy (DOE) in deciding which of several gas transfer system (GTS) options should be selected. The decision objectives for this case study, i.e., risk and cost, were directly derived from the DOE guidelines. Influence diagrams were used to define the structure of the decision problem and clearly delineate the flow if information. A set of performance matrices wee used in conjunction with the influence diagrams to assess and evaluate the degree to which the objectives of the case study were met. These performance measures were extracted from technical models, design and operating data, and professional judgments. The results were aggregated to provide an overall evaluation of the different design options of the gas transfer system. Consequently, the results of this analysis were used as an aid to DOE to select a viable GTS option.

  5. Life cycle assessment of bagasse waste management options

    SciTech Connect

    Kiatkittipong, Worapon; Wongsuchoto, Porntip; Pavasant, Prasert

    2009-05-15

    Bagasse is mostly utilized for steam and power production for domestic sugar mills. There have been a number of alternatives that could well be applied to manage bagasse, such as pulp production, conversion to biogas and electricity production. The selection of proper alternatives depends significantly on the appropriateness of the technology both from the technical and the environmental points of view. This work proposes a simple model based on the application of life cycle assessment (LCA) to evaluate the environmental impacts of various alternatives for dealing with bagasse waste. The environmental aspects of concern included global warming potential, acidification potential, eutrophication potential and photochemical oxidant creation. Four waste management scenarios for bagasse were evaluated: landfilling with utilization of landfill gas, anaerobic digestion with biogas production, incineration for power generation, and pulp production. In landfills, environmental impacts depended significantly on the biogas collection efficiency, whereas incineration of bagasse to electricity in the power plant showed better environmental performance than that of conventional low biogas collection efficiency landfills. Anaerobic digestion of bagasse in a control biogas reactor was superior to the other two energy generation options in all environmental aspects. Although the use of bagasse in pulp mills created relatively high environmental burdens, the results from the LCA revealed that other stages of the life cycle produced relatively small impacts and that this option might be the most environmentally benign alternative.

  6. Management options for recycling radioactive scrap metals

    SciTech Connect

    Dehmel, J.C.; MacKinney, J.; Bartlett, J.

    1997-02-01

    The feasibility and advantages of recycling radioactive scrap metals (RSM) have yet to be assessed, given the unique technical, regulatory, safety, and cost-benefit issues that have already been raised by a concerned recycling industry. As is known, this industry has been repeatedly involved with the accidental recycling of radioactive sources and, in some cases, with costly consequences. If recycling were deemed to be a viable option, it might have to be implemented with regulatory monitoring and controls. Its implementation may have to consider various and complex issues and address the requirements and concerns of distinctly different industries. There are three basic options for the recycling of such scraps. They are: (1) recycling through the existing network of metal-scrap dealers and brokers, (2) recycling directly and only with specific steelmills, or (3) recycling through regional processing centers. Under the first option, scrap dealers and brokers would receive material from RSM generators and determine at which steelmills such scraps would be recycled. For the second option, RSM generators would deal directly with selected steelmills under specific agreements. For the third option, generators would ship scraps only to regional centers for processing and shipment to participating steelmills. This paper addresses the potential advantages of each option, identifies the types of arrangements that would need to be secured among all parties, and attempts to assess the receptivity of the recycling industry to each option.

  7. Dark circles: etiology and management options.

    PubMed

    Friedmann, Daniel P; Goldman, Mitchel P

    2015-01-01

    Given their multifactorial nature and the fact that individual patients may have more than a single underlying cause, cosmetic practitioners should be well versed in a number of potential treatment options encompassing all facets of under-eye dark circles. New therapeutic options are also forthcoming. Longer-lasting HA fillers, wavelength tunable laser devices, and topicals speeding up healing and enhancing results after fractionated laser therapy will all serve to make the future of dark circle treatment unabatedly bright. PMID:25440739

  8. Use of optimization modeling to evaluate industrial waste reduction options: Application to a sour gas plant

    SciTech Connect

    Roberge, H.D. ); Sikora, R.P. ); Baetz, B.W. . Dept. of Civil Engineering)

    1994-01-01

    This note reports on a study of waste reduction options for the upstream oil and gas industry and involves the application of a waste reduction optimization model to a generic sour gas plant. The waste reduction optimization model is meant as an aid for decision-making relating to the implementation of waste reduction options. The generic facility was developed from process knowledge provided by industry members of a project steering committee, as well as waste management information from industry manuals and represents a facility of average capacity and typical configuration. Several waste minimization options were modeled for selected waste streams. The selected streams were chosen based upon waste flows and disposal costs and their potential for waste reduction. The results of the modeling for the generic sour gas plant have shown that a set of cost-effective waste reduction options exist, there is significant potential for reducing the total quantity of waste to be managed and disposed of, and that implementation of the options would lead to considerable cost savings. The value and usefulness of the modeling approach lie not only in the generated results, but also in the fact that to construct the model, relevant waste flows and every possible manner that these waste flows can be minimized or processed are systematically identified. Once modeled, the parameters can be readily manipulated to determine various possible waste management strategies. To effectively use the modeling approach, the waste reduction team should have knowledge of the plant processes, existing waste management practices and costs, information on potential waste reduction options and technologies, as well as experience in mathematical modeling and analysis.

  9. Melasma: clinical diagnosis and management options.

    PubMed

    Rodrigues, Michelle; Pandya, Amit G

    2015-08-01

    Melasma is a common acquired disorder of pigmentation most commonly seen in those with skin of colour. It has long been a condition that is frustrating for both the dermatologist and patient to treat. This article provides a review of the literature on melasma and examines, in detail, various treatment options currently available to treat it. PMID:25754098

  10. A real-world way to manage real options.

    PubMed

    Copeland, Tom; Tufano, Peter

    2004-03-01

    Each corporate growth project is an option, in the sense that managers face choices--push ahead or pull back--along the way. Yet many companies hesitate to apply options theory to initiatives such as R&D and geographic expansion, partly because these "real" options are highly complex. In this article, the authors make the case that the complexity of real options can be eased through the use of a binomial valuation model. Many of the problems with real-options analysis stem from the use of the Black-Scholes-Merton model, which isn't suited to real options. Binomial models, by contrast, are simpler mathematically, and you can tinker with a binomial model until it closely reflects the project you wish to value. Suppose your company is considering investing in a new plant. To use the binomial model, you must create an "event tree" to figure out the full range of possible values for the plant during the project's lifetime--next year, at the end of the design phase, upon completion. Then you work backward from the value at completion, factoring in the various investments, to determine the value of the project today. These calculations provide you with numbers for all the possible future values of the option at the various points where a decision needs to be made on whether to continue with the project. The authors also address another criticism of real options: that gaps often arise between theoretical and realized values of options of all types. Such gaps may be largely the result of managers exercising options at the wrong time. To improve the way it manages its real options, a company can look out for the decision trigger points that correspond to the nodes on a binomial decision tree. The trigger points should not only tell managers when they need to decide on exercise but also specify rules governing the exercise decisions. PMID:15029793

  11. Economic analysis of emerald ash borer (Coleoptera: Buprestidae) management options.

    PubMed

    Vannatta, A R; Hauer, R H; Schuettpelz, N M

    2012-02-01

    Emerald ash borer, Agrilus planipennis (Fairmaire) (Coleoptera: Buprestidae), plays a significant role in the health and extent of management of native North American ash species in urban forests. An economic analysis of management options was performed to aid decision makers in preparing for likely future infestations. Separate ash tree population valuations were derived from the i-Tree Streets program and the Council of Tree and Landscape Appraisers (CTLA) methodology. A relative economic analysis was used to compare a control option (do-nothing approach, only removing ash trees as they die) to three distinct management options: 1) preemptive removal of all ash trees over a 5 yr period, 2) preemptive removal of all ash trees and replacement with comparable nonash trees, or 3) treating the entire population of ash trees with insecticides to minimize mortality. For each valuation and management option, an annual analysis was performed for both the remaining ash tree population and those lost to emerald ash borer. Retention of ash trees using insecticide treatments typically retained greater urban forest value, followed by doing nothing (control), which was better than preemptive removal and replacement. Preemptive removal without tree replacement, which was the least expensive management option, also provided the lowest net urban forest value over the 20-yr simulation. A "no emerald ash borer" scenario was modeled to further serve as a benchmark for each management option and provide a level of economic justification for regulatory programs aimed at slowing the movement of emerald ash borer. PMID:22420272

  12. Primary Sclerosing Cholangitis: Therapeutic Options and Surveillance Management

    PubMed Central

    Kumar, Aditi; Wheatley, Daniel; Puttanna, Amar

    2016-01-01

    Primary sclerosing cholangitis is a chronic immune-mediated liver disease. Though rare, it poses several clinical concerns for the managing physician. There are currently limited therapeutic options in the management of the condition and weak evidence base behind them. Endoscopic intervention is limited to those patients with obstructing stricture-related disease, and even liver transplantation has a risk of disease recurrence. Surveillance for inflammatory bowel disorders, metabolic bone disease, and malignancy is paramount when managing such patients. This article provides an overview of the condition with further focus on current therapeutic options and guidance on surveillance management. PMID:27330336

  13. [Options for stress management in obesity treatment].

    PubMed

    Czeglédi, Edit

    2016-02-14

    Overeating and physical inactivity are of great importance in the etiology of obesity. Psychological factors are often found in the background of life style. Chronic stress can contribute to physical inactivity and behaviors that hinder the keeping of a diet (e.g., irregular eating pattern, emotional eating). Results of randomized controlled trials show that relaxation can reduce emotional eating, improve cognitive restraint, and thereby reduce weight. However, stress management is more than relaxation. It consists of adaptive emotion-focused and problem-focused coping strategies and skills to improve relationships. Deflection skills may help in replacing emotional eating with other behaviors. Cognitive restructuring, saying no, and problem solving help to prevent or manage conflicts and difficulties otherwise would result in overeating due to distress. Developing stress management skills may result in greater compliance with the treatment. The techniques presented in the study can be easily applied by general practitioners or specialists, and provide tools for optimizing obesity treatment. PMID:26853727

  14. Urinary Incontinence: Management and Treatment Options

    ERIC Educational Resources Information Center

    Griebling, Tomas L.

    2009-01-01

    Urinary incontinence, defined as the involuntary leakage of urine, is a common health problem in both women and men. Children may also suffer from this condition. Management and treatment of urinary incontinence depends primarily on the specific type of incontinence and the underlying problem causing the leakage for a given patient. Because…

  15. MANURE MANAGEMENT: ALFALFA FIELDS GIVE US OPTIONS

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The average cow in the U.S. produces more than 18,000 lbs. of milk each year and generates about 42,000 lbs. of manure. Manure management is not the only task on the farmer's 'to do' list, but in today’s world it is increasingly important to do it right. Although alfalfa acreage is a relatively smal...

  16. Management options for minimal hepatic encephalopathy.

    PubMed

    Bajaj, Jasmohan S

    2008-12-01

    Minimal hepatic encephalopathy (MHE) is a neurocognitive dysfunction that is present in the majority of patients with cirrhosis. MHE has a characteristic cognitive profile that cannot be diagnosed clinically. This cognitive dysfunction is independent of sleep dysfunction or problems with overall intelligence. MHE has a significant impact on quality of life, the ability to function in daily life and progression to overt hepatic encephalopathy. Driving ability can be impaired in MHE and this may be a significant factor behind motor vehicle accidents. A crucial aspect of the clinical care of MHE patients is their driving history, which is often ignored during routine care and can add a vital dimension to the overall disease assessment. Driving history should be an integral part of the care of patients with MHE. The preserved communication skills and lack of specific signs and insight make MHE difficult to diagnose. The predominant strategies for MHE diagnosis are psychometric or neurophysiological testing. These are usually limited by financial, normative or time constraints. Studies into inhibitory control, cognitive drug research and critical flicker frequency tests are encouraging. These tests do not require a psychologist for administration and interpretation. Lactulose and probiotics have been studied for their potential use as therapies for MHE, but these are not standard-of-care practices at this time. Therapy can improve the quality of life in MHE patients but the natural history, specific diagnostic strategies and treatment options are still being investigated. PMID:19090738

  17. Geothermal Produced Fluids: Characteristics, Treatment Technologies, and Management Options

    SciTech Connect

    Finster, Molly; Clark, Corrie; Schroeder, Jenna; Martino, Louis

    2015-10-01

    Geothermal power plants use geothermal fluids as a resource and create waste residuals as part of the power generation process. Both the geofluid resource and the waste stream are considered produced fluids. The chemical and physical nature of produced fluids can have a major impact on the geothermal power industry and can influence the feasibility of geothermal power development, exploration approaches, power plant design, operating practices, and the reuse or disposal of residuals. In general, produced fluids include anything that comes out of a geothermal field and that subsequently must be managed on the surface. These fluids vary greatly depending on the geothermal reservoir being harnessed, power plant design, and the life cycle stage in which the fluid exists, but generally include water and fluids used to drill geothermal wells, fluids used to stimulate wells in enhanced geothermal systems, and makeup and/or cooling water used during operation of a geothermal power plant. Additional geothermal-related produced fluids include many substances that are similar to waste streams from the oil and gas industry, such as scale, flash tank solids, precipitated solids from brine treatment, hydrogen sulfide, and cooling-tower-related waste. This review paper aims to provide baseline knowledge on specific technologies and technology areas associated with geothermal power production. Specifically, this research focused on the management techniques related to fluids produced and used during the operational stage of a geothermal power plant; the vast majority of which are employed in the generation of electricity. The general characteristics of produced fluids are discussed. Constituents of interest that tend to drive the selection of treatment technologies are described, including total dissolved solids, noncondensable gases, scale and corrosion, silicon dioxide, metal sulfides, calcium carbonate, corrosion, metals, and naturally occurring radioactive material. Management

  18. Onychomycosis: Evaluation, Treatment Options, Managing Recurrence, and Patient Outcomes.

    PubMed

    Vlahovic, Tracey C

    2016-07-01

    Onychomycosis is the most common nail disease seen in podiatric practice. Effective long-term management remains problematic. We need to treat onychomycosis effectively to prevent its progression into a severe, debilitating, and painful condition, and to manage recurrence. With new agents now available and greater discussion on management strategies, this article reviews the appropriate evaluation of the disease, treatment options, and optimal patient outcomes. PMID:27215153

  19. Global plutonium management: A security option

    SciTech Connect

    Sylvester, K.W.B.

    1998-12-31

    The US surplus plutonium disposition program was created to reduce the proliferation risk posed by the fissile material from thousands of retired nuclear weapons. The Department of Energy has decided to process its Put into a form as secure as Pu in civilian spent fuel. While implementation issues have been considered, a major one (Russian reciprocity) remains unresolved. Russia has made disposition action conditional on extracting the fuel value of its Pu but lacks the infrastructure to do so. Assistance in the construction of the required facilities would conflict with official US policy opposing the development of a Pu fuel cycle. The resulting stagnation provides impetus for a reevaluation of US nonproliferation objectives and Pu disposition options. A strategy for satisfying Russian fuel value concerns and reducing the proliferation risk posed by surplus weapons-grade plutonium (WGPu) is proposed. The effectiveness of material alteration (e.g., isotopic, chemical, etc.{hor_ellipsis}) at reducing the desire, ability and opportunity for proliferation is assessed. Virtually all the security benefits attainable by material processing can be obtained by immobilizing Pu in large unit size/mass monoliths without a radiation barrier. Russia would be allowed to extract the Pu at a future date for use as fuel in a verifiable manner. Remote tracking capability, if proven feasible, would further improve safeguarding capability. As an alternate approach, the US could compensate Russia for its Pu, allowing it to be disposed of or processed elsewhere. A market based method for pricing Pu is proposed. Surplus Pu could represent access to nuclear fuel at a fixed price at a future date. This position can be replicated in the uranium market and priced using derivative theory. The proposed strategy attempts to meet nonproliferation objectives by recognizing technical limitations and satisfying political constraints.

  20. Options for gas-to-liquids technology in Alaska

    SciTech Connect

    Robertson, E.P.

    1999-12-01

    The purpose of this work was to assess the effect of applying new technology to the economics of a proposed natural gas-to-liquids (GTL) plant, to evaluate the potential of a slower-paced, staged deployment of GTL technology, and to evaluate the effect of GTL placement of economics. Five scenarios were economically evaluated and compared: a no-major-gas-sales scenario, a gas-pipeline/LNG scenario, a fast-paced GTL development scenario, a slow-paced GTL development scenario, and a scenario which places the GTL plant in lower Alaska, instead of on the North Slope. Evaluations were completed using an after-tax discounted cash flow analysis. Results indicate that the slow-paced GTL scenario is the only one with a rate of return greater than 10%. The slow-paced GTL development would allow cost saving on subsequent expansions. These assumed savings, along with the lowering of the transportation tariff, combine to distinguish this option for marketing the North Slope gas from the other scenarios. Critical variables that need further consideration include the GTL plant cost, the GTL product premium, and operating and maintenance costs.

  1. Options for Gas-to-Liquids Technology in Alaska

    SciTech Connect

    Robertson, Eric Partridge

    1999-10-01

    The purposes of this work was to assess the effect of applying new technology to the economics of a proposed natural gas-to-liquids (GTL) plant, to evaluate the potential of a slower-paced, staged deployment of GTL technology, and to evaluate the effect of GTL placement of economics. Five scenarios were economically evaluated and compared: a no-major-gas-sales scenario, a gas-pipeline/LNG scenario, a fast-paced GTL development scenario, a slow-paced GTL development scenario, and a scenario which places the GTL plant in lower Alaska, instead of on the North Slope. Evaluations were completed using an after-tax discounted cash flow analysis. Results indicate that the slow-paced GTL scenario is the only one with a rate of return greater than 10 percent. The slow-paced GTL development would allow cost saving on subsequent expansions. These assumed savings, along with the lowering of the transportation tariff, combine to distinquish this option for marketing the North Slope gas from the other scenarios. Critical variables that need further consideration include the GTL plant cost, the GTL product premium, and operating and maintenance costs.

  2. Shale gas wastewater management under uncertainty.

    PubMed

    Zhang, Xiaodong; Sun, Alexander Y; Duncan, Ian J

    2016-01-01

    This work presents an optimization framework for evaluating different wastewater treatment/disposal options for water management during hydraulic fracturing (HF) operations. This framework takes into account both cost-effectiveness and system uncertainty. HF has enabled rapid development of shale gas resources. However, wastewater management has been one of the most contentious and widely publicized issues in shale gas production. The flowback and produced water (known as FP water) generated by HF may pose a serious risk to the surrounding environment and public health because this wastewater usually contains many toxic chemicals and high levels of total dissolved solids (TDS). Various treatment/disposal options are available for FP water management, such as underground injection, hazardous wastewater treatment plants, and/or reuse. In order to cost-effectively plan FP water management practices, including allocating FP water to different options and planning treatment facility capacity expansion, an optimization model named UO-FPW is developed in this study. The UO-FPW model can handle the uncertain information expressed in the form of fuzzy membership functions and probability density functions in the modeling parameters. The UO-FPW model is applied to a representative hypothetical case study to demonstrate its applicability in practice. The modeling results reflect the tradeoffs between economic objective (i.e., minimizing total-system cost) and system reliability (i.e., risk of violating fuzzy and/or random constraints, and meeting FP water treatment/disposal requirements). Using the developed optimization model, decision makers can make and adjust appropriate FP water management strategies through refining the values of feasibility degrees for fuzzy constraints and the probability levels for random constraints if the solutions are not satisfactory. The optimization model can be easily integrated into decision support systems for shale oil/gas lifecycle

  3. Options for perioperative pain management in neurosurgery

    PubMed Central

    Vadivelu, Nalini; Kai, Alice M; Tran, Daniel; Kodumudi, Gopal; Legler, Aron; Ayrian, Eugenia

    2016-01-01

    Moderate-to-severe pain following neurosurgery is common but often does not get attention and is therefore underdiagnosed and undertreated. Compounding this problem is the traditional belief that neurosurgical pain is inconsequential and even dangerous to treat. Concerns about problematic effects associated with opioid analgesics such as nausea, vomiting, oversedation, and increased intracranial pressure secondary to elevated carbon dioxide tension from respiratory depression have often led to suboptimal postoperative analgesic strategies in caring for neurosurgical patients. Neurosurgical patients may have difficulty or be incapable of communicating their need for analgesics due to neurologic deficits, which poses an additional challenge. Postoperative pain control should be a priority, because pain adversely affects recovery and patient outcomes. Inconsistent practices and the quality of current analgesic strategies for neurosurgical patients still leave room for improvement. Given the complexity of postoperative pain management for these patients, multimodal strategies are often required to optimize pain control and at the same time limit undesired side effects. PMID:26929661

  4. [Conservative management option in elderly patients].

    PubMed

    Guienne, Véronique; Parahy, Sophie; Testa, Angelo

    2016-04-01

    "Conservative management" is as an alternative care pathway offered to patients who elect not to start dialysis often because of a heavy burden of comorbid illness and advanced ages. Our research, characterized by a transdisciplinary medical and social investigation and based on a case by case analysis, intends to understand the reasons and the context in which this choice has to be made. On the first hand, the results show that all the studied cases can be explained by two variables, the latter can be combined: when the patient is suffering from important clinical pathologies; when the patient lives with this renal failure as a trouble linked to the age. On the second hand, two important questions are raised: the first one is about the medical practices and stems from the influence of criteria always present in the decisions to take (the paramedical exams and the clinical information from the interview, the patient's examination and the discussion with his/her close family member). The second one is about the patient's autonomy and can be analyzed regarding to his/her capacity to express his/her choices and share it with his close family. But also, to live in according to his age, that is to say the relation he/she has with his/her edged body and to the limits of his/her existence. The key notion of shared decision-making renewed is to refer in the consultation and the choices to take to the question of the advantages/drawbacks for the patient's life and not only to the question of the connection between the results and the medical risks, in order to exchange view with the patient on his/her future life and not only on the condition of his failed organ. PMID:26725173

  5. Grazing management options in meeting objectives of grazing experiments

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Decisions on which grazing management option to use in grazing experiments can be critical in meeting research objectives and generating information for the scientific community or technologies that meets the needs of forage-based enterprises. It is necessary to have an understanding of animal per...

  6. Thermal management system options for high power space platforms

    NASA Technical Reports Server (NTRS)

    Sadunas, J. A.; Lehtinen, A.; Parish, R.

    1985-01-01

    Thermal Management System (TMS) design options for a high power (75kWe), low earth orbit, multimodule space platform were investigated. The approach taken was to establish a baseline TMS representative of current technology, and to make incremental improvements through successive subsystem trades that lead to a candidate TMS. The TMS trades included centralized and decentralized transport, single-phase and two-phase transport, alternate working fluids, liquid loop and heat pipe radiators, deployed fixed, body mounted and steerable radiators, and thermal storage. The subsystem options were evaluated against criteria such as weight, TMS power requirement, reliability, system isothermality penalty, and growth potential.

  7. Using real options analysis to support strategic management decisions

    NASA Astrophysics Data System (ADS)

    Kabaivanov, Stanimir; Markovska, Veneta; Milev, Mariyan

    2013-12-01

    Decision making is a complex process that requires taking into consideration multiple heterogeneous sources of uncertainty. Standard valuation and financial analysis techniques often fail to properly account for all these sources of risk as well as for all sources of additional flexibility. In this paper we explore applications of a modified binomial tree method for real options analysis (ROA) in an effort to improve decision making process. Usual cases of use of real options are analyzed with elaborate study on the applications and advantages that company management can derive from their application. A numeric results based on extending simple binomial tree approach for multiple sources of uncertainty are provided to demonstrate the improvement effects on management decisions.

  8. Perioperative pain management in hip arthroscopy; what options are there?

    PubMed

    Bech, N H; Hulst, A H; Spuijbroek, J A; van Leuken, L L A; Haverkamp, D

    2016-08-01

    Hip arthroscopy is a fast growing orthopedic field of expertise. As in any field of surgery adequate postoperative pain management regimes are of utmost importance. The purpose of this review is to provide an overview of current knowledge on anesthetic options for perioperative pain management for hip arthroscopy. We searched the Pubmed/Medline and Embase database for literature and included 10 studies for our analysis. Because of the variety of pain scales and different ways of measured pain no meta-analysis could be performed and a descriptive review is performed. There are several types of pain regimens that can mostly be divided in two groups: local anesthetics and nerve blocks. Included studies show a rather large variation in reported visual analogue scale scores, post anesthesia care unit admission time and opioid usage. There are several anesthetic options available for hip arthroscopy. Different studies use different dosages, anesthetic regimens and different protocols; this partly explains the differences between studies with similar techniques. Peripheral nerve blocks seems promising but regarding current literature no clear recommendation can be made about what the best perioperative pain management option is, an overview of all reported techniques is given. PMID:27583156

  9. Perioperative pain management in hip arthroscopy; what options are there?

    PubMed Central

    Bech, N. H.; Hulst, A. H.; Spuijbroek, J. A.; van Leuken, L. L. A.; Haverkamp, D.

    2016-01-01

    Hip arthroscopy is a fast growing orthopedic field of expertise. As in any field of surgery adequate postoperative pain management regimes are of utmost importance. The purpose of this review is to provide an overview of current knowledge on anesthetic options for perioperative pain management for hip arthroscopy. We searched the Pubmed/Medline and Embase database for literature and included 10 studies for our analysis. Because of the variety of pain scales and different ways of measured pain no meta-analysis could be performed and a descriptive review is performed. There are several types of pain regimens that can mostly be divided in two groups: local anesthetics and nerve blocks. Included studies show a rather large variation in reported visual analogue scale scores, post anesthesia care unit admission time and opioid usage. There are several anesthetic options available for hip arthroscopy. Different studies use different dosages, anesthetic regimens and different protocols; this partly explains the differences between studies with similar techniques. Peripheral nerve blocks seems promising but regarding current literature no clear recommendation can be made about what the best perioperative pain management option is, an overview of all reported techniques is given. PMID:27583156

  10. Dietary and nutraceutical options for managing the hypertriglyceridemic patient.

    PubMed

    Pins, Joel J; Keenan, Joseph M

    2006-01-01

    Scientific evidence continues to accumulate regarding fasting serum triglycerides as an independent risk factor for coronary heart disease. In response, the National Cholesterol Education Program has revised the acceptable level of fasting triglycerides from <200 mg/dL to <150 mg/dL. A significant percentage of Americans suffer from hypertriglyceridemia, and considering the expanding numbers of individuals who are physically inactive, overweight, and suffering from the metabolic syndrome, it is expected that these numbers will continue to rise over the next decade. Fortunately, nutraceutical and lifestyle options have been shown to substantially and consistently reduce this risk factor. This review will focus on management options for the hypertriglyceridemic patient with an emphasis on nicotinic acid, pantethine, fish oils (eicosapentaenoic and docosahexaenoic acids), and modified carbohydrate diets. PMID:16760691

  11. Pharmacologic options for the treatment and management of food allergy.

    PubMed

    Kobernick, Aaron K; Chambliss, Jeffrey; Burks, A Wesley

    2015-01-01

    Food allergy affects approximately 5% of adults and 8% of children in developed countries, and there is currently no cure. Current pharmacologic management is limited to using intramuscular epinephrine or oral antihistamines in response to food allergen exposure. Recent trials have examined the efficacy and safety of subcutaneous, oral, sublingual, and epicutaneous immunotherapy, with varying levels of efficacy and safety demonstrated. Bacterial adjuvants, use of anti-IgE monoclonal antibodies, and Chinese herbal formulations represent exciting potential for development of future pharmacotherapeutic agents. Ultimately, immunotherapy may be a viable option for patients with food allergy, although efficacy and safety are likely to be less than ideal. PMID:26289224

  12. Agricultural land management options following large-scale environmental contamination.

    PubMed

    Vandenhove, Hildegarde; Turcanu, Catrinel

    2011-07-01

    The recent events at the Fukushima Daiichi nuclear power plant, in Japan, have raised questions about the accumulation of radionuclides in soils, the transfer in the food chain, and the possibility for restricted land use in the foreseeable future. This article summarizes what is generally understood about the application of agricultural countermeasures as a land management option to reduce the transfer of radionuclides in the food chain and to facilitate the return of potentially affected soils to agricultural practices in the vicinity of the Fukushima plant. PMID:21608113

  13. Participatory groundwater management in Jordan: Development and analysis of options

    NASA Astrophysics Data System (ADS)

    Chebaane, Mohamed; El-Naser, Hazim; Fitch, Jim; Hijazi, Amal; Jabbarin, Amer

    Groundwater over-exploitation has been on the rise in Jordan. Competing demands have grown in the face of perennial water shortages, a situation which has been exacerbated by drought conditions in the past decade. This paper reports findings of a project in which management options to address over-exploitation were developed for one of Jordan's principal aquifer systems, the Amman-Zarqa Basin. Options for addressing the situation were developed through a participatory approach that involved government officials and various public and private sector interest groups. Particular efforts were made to involve well irrigators, who are likely to be heavily impacted by the changes required to reduce groundwater pumping to a sustainable level. With information obtained from a rapid appraisal survey as well as from interviews with farmers, community groups, government officials, and technical experts, an extensive set of options was identified for evaluation. Based on integrated hydrogeologic, social, and economic analysis, five complementary management options were recommended for implementation. These included the establishment of an Irrigation Advisory Service, buying out farm wells, placing firm limits on well ion and irrigated crop areas, exchanging treated wastewater for groundwater, and measures to increase the efficiency of municipal and industrial water use. Various combinations and levels of these options were grouped in scenarios, representing possible implementation strategies. The scenarios were designed to assist decision makers, well owners and other stakeholders in moving gradually towards a sustainable ion regime. Social and economic aspects of each option and scenario were analyzed and presented to stakeholders, together with a of legal, institutional and environmental ramifications. Combining scientific analysis with a participatory approach in the Amman Zarqa Basin groundwater management was devised as a prototype to be used in the management of other

  14. Evaluation of flammable gas monitoring options for waste tank intrusive activities

    SciTech Connect

    Shultz, M.V.

    1996-09-03

    This calc note documents an evaluation of three options for monitoring hydrogen during waste tank intrusive activities. The three options are (1) one Combustible Gas Monitor with an operator monitoring the readout, (2) two CGMs with separate operators monitoring each gas monitor, and (3) one CGM with audible alarm, no dedicated operator monitoring readout. A comparison of the failure probabilities of the three options is provided. This Calculation Note supports the Flammable Gas Analysis for TWRS FSAR and BIO. This document is not to be used as the sole basis to authorize activities or to change authorization, safety or design bases.

  15. The Oil and Natural Gas Knowledge Management Database from NETL

    DOE Data Explorer

    The Knowledge Management Database (KMD) Portal provides four options for searching the documents and data that NETL-managed oil and gas research has produced over the years for DOE’s Office of Fossil Energy. Information includes R&D carried out under both historical and ongoing DOE oil and gas research and development (R&D). The Document Repository, the CD/DVD Library, the Project Summaries from 1990 to the present, and the Oil and Natural Gas Program Reference Shelf provide a wide range of flexibility and coverage.

  16. Fuel cell gas management system

    DOEpatents

    DuBose, Ronald Arthur

    2000-01-11

    A fuel cell gas management system including a cathode humidification system for transferring latent and sensible heat from an exhaust stream to the cathode inlet stream of the fuel cell; an anode humidity retention system for maintaining the total enthalpy of the anode stream exiting the fuel cell equal to the total enthalpy of the anode inlet stream; and a cooling water management system having segregated deionized water and cooling water loops interconnected by means of a brazed plate heat exchanger.

  17. Strategic Environmental Assessment of Greenhouse Gas Mitigation Options in the Canadian Agricultural Sector

    NASA Astrophysics Data System (ADS)

    Noble, Bram F.; Christmas, Lisa M.

    2008-01-01

    This article presents a methodological framework for strategic environmental assessment (SEA) application. The overall objective is to demonstrate SEA as a systematic and structured policy, plan, and program (PPP) decision support tool. In order to accomplish this objective, a stakeholder-based SEA application to greenhouse gas (GHG) mitigation policy options in Canadian agriculture is presented. Using a mail-out impact assessment exercise, agricultural producers and nonproducers from across the Canadian prairie region were asked to evaluate five competing GHG mitigation options against 13 valued environmental components (VECs). Data were analyzed using multi-criteria and exploratory analytical techniques. The results suggest considerable variation in perceived impacts and GHG mitigation policy preferences, suggesting that a blanket policy approach to GHG mitigation will create gainers and losers based on soil type and associate cropping and on-farm management practices. It is possible to identify a series of regional greenhouse gas mitigation programs that are robust, socially meaningful, and operationally relevant to both agricultural producers and policy decision makers. The assessment demonstrates the ability of SEA to address, in an operational sense, environmental problems that are characterized by conflicting interests and competing objectives and alternatives. A structured and systematic SEA methodology provides the necessary decision support framework for the consideration of impacts, and allows for PPPs to be assessed based on a much broader set of properties, objectives, criteria, and constraints whereas maintaining rigor and accountability in the assessment process.

  18. An environmental analysis for comparing waste management options and strategies.

    PubMed

    Marchettini, N; Ridolfi, R; Rustici, M

    2007-01-01

    The debate on different waste management practices has become an issue of utmost importance as human activities have overloaded the assimilative capacity of the biosphere. Recent Italian law on solid waste management recommends an increase in material recycling and energy recovery, and only foresees landfill disposal for inert materials and residues from recovery and recycling. A correct waste management policy should be based on the principles of sustainable development, according to which our refuse is not simply regarded as something to eliminate but rather as a potential resource. This requires the creation of an integrated waste management plan that makes full use of all available technologies. In this context, eMergy analysis is applied to evaluate three different forms of waste treatment and construct an approach capable of assessing the whole strategy of waste management. The evaluation included how much investment is needed for each type of waste management and how much "utility" is extracted from wastes, through the use of two indicators: Environmental yield ratio (EYR) and Net eMergy. Our results show that landfill is the worst system in terms of eMergy costs and eMergy benefits. Composting is the most efficient system in recovering eMergy (highest EYR) from municipal solid waste (MSW) while incineration is capable of saving the greatest quantity of eMergy per gram of MSW (highest net eMergy). This analysis has made it possible to assess the sustainability and the efficiency of individual options but could also be used to assess a greater environmental strategy for waste management, considering a system that might include landfills, incineration, composting, etc. PMID:16765586

  19. Mixed Waste Management Options: 1995 Update. National Low-Level Waste Management Program

    SciTech Connect

    Kirner, N.; Kelly, J.; Faison, G.; Johnson, D.

    1995-05-01

    In the original mixed Waste Management Options (DOE/LLW-134) issued in December 1991, the question was posed, ``Can mixed waste be managed out of existence?`` That study found that most, but not all, of the Nation`s mixed waste can theoretically be managed out of existence. Four years later, the Nation is still faced with a lack of disposal options for commercially generated mixed waste. However, since publication of the original Mixed Waste Management Options report in 1991, limited disposal capacity and new technologies to treat mixed waste have become available. A more detailed estimate of the Nation`s mixed waste also became available when the US Environmental Protection Agency (EPA) and the US Nuclear Regulatory Commission (NRC) published their comprehensive assessment, titled National Profile on Commercially Generated Low-Level Radioactive Mixed Waste (National Profile). These advancements in our knowledge about mixed waste inventories and generation, coupled with greater treatment and disposal options, lead to a more applied question posed for this updated report: ``Which mixed waste has no treatment option?`` Beyond estimating the volume of mixed waste requiring jointly regulated disposal, this report also provides a general background on the Atomic Energy Act (AEA) and the Resource Conservation and Recovery Act (RCRA). It also presents a methodical approach for generators to use when deciding how to manage their mixed waste. The volume of mixed waste that may require land disposal in a jointly regulated facility each year was estimated through the application of this methodology.

  20. Options and costs for offsite disposal of oil and gas exploration and production wastes.

    SciTech Connect

    Puder, M. G.; Veil, J. A.; Environmental Science Division

    2007-01-01

    In the United States, most of the exploration and production (E&P) wastes generated at onshore oil and gas wells are disposed of or otherwise managed at the well site. Certain types of wastes are not suitable for onsite management, and some well locations in sensitive environments cannot be used for onsite management. In these situations, operators must transport the wastes offsite for disposal. In 1997, Argonne National Laboratory (Argonne) prepared a report that identified offsite commercial disposal facilities in the United States. This information has since become outdated. Over the past year, Argonne has updated the study through contacts with state oil and gas agencies and commercial disposal companies. The new report, including an extensive database for more than 200 disposal facilities, provides an excellent reference for information about commercial disposal operations. This paper describes Argonne's report. The national study provides summaries of the types of offsite commercial disposal facilities found in each state. Data are presented by waste type and by disposal method. The categories of E&P wastes in the database include: contaminated soils, naturally occurring radioactive material (NORM), oil-based muds and cuttings, produced water, tank bottoms, and water-based muds and cuttings. The different waste management or disposal methods in the database involve: bioremediation, burial, salt cavern, discharge, evaporation, injection, land application, recycling, thermal treatment, and treatment. The database includes disposal costs for each facility. In the United States, most of the 18 billion barrels (bbl) of produced water, 149 million bbl of drilling wastes, and 21 million bbl of associated wastes generated at onshore oil and gas wells are disposed of or otherwise managed at the well site. However, under certain conditions, operators will seek offsite management options for these E&P wastes. Commercial disposal facilities are offsite businesses that

  1. Quantitative option analysis for implementation and management of landfills.

    PubMed

    Kerestecioğlu, Merih

    2016-09-01

    The selection of the most feasible strategy for implementation of landfills is a challenging step. Potential implementation options of landfills cover a wide range, from conventional construction contracts to the concessions. Montenegro, seeking to improve the efficiency of the public services while maintaining affordability, was considering privatisation as a way to reduce public spending on service provision. In this study, to determine the most feasible model for construction and operation of a regional landfill, a quantitative risk analysis was implemented with four steps: (i) development of a global risk matrix; (ii) assignment of qualitative probabilities of occurrences and magnitude of impacts; (iii) determination of the risks to be mitigated, monitored, controlled or ignored; (iv) reduction of the main risk elements; and (v) incorporation of quantitative estimates of probability of occurrence and expected impact for each risk element in the reduced risk matrix. The evaluated scenarios were: (i) construction and operation of the regional landfill by the public sector; (ii) construction and operation of the landfill by private sector and transfer of the ownership to the public sector after a pre-defined period; and (iii) operation of the landfill by the private sector, without ownership. The quantitative risk assessment concluded that introduction of a public private partnership is not the most feasible option, unlike the common belief in several public institutions in developing countries. A management contract for the first years of operation was advised to be implemented, after which, a long term operating contract may follow. PMID:27354014

  2. Impact assessment of waste management options in Singapore.

    PubMed

    Tan, Reginald B H; Khoo, Hsien H

    2006-03-01

    This paper describes the application of life cycle assessment for evaluating various waste management options in Singapore, a small-island city state. The impact assessment method by SimaPro is carried out for comparing the potential environmental impacts of waste treatment options including landfilling, incineration, recycling, and composting. The inventory data include gases and leachate from landfills, air emissions and energy recovery from incinerators, energy (and emission) savings from recycling, composting gases, and transport pollution. The impact assessment results for climate change, acidification, and ecotoxicity show that the incineration of materials imposes considerable harm to both human health and the environment, especially for the burning of plastics, paper/cardboard, and ferrous metals. The results also show that, although some amount of energy can be derived from the incineration of wastes, these benefits are outweighed by the air pollution (heavy metals and dioxins/furans) that incinerators produce. For Singapore, landfill gases and leachate generate minimal environmental damage because of the nation's policy to landfill only 10% of the total disposed wastes. Land transportation and separation of waste materials also pose minimal environmental damage. However, sea transportation to the landfill could contribute significantly to acidification because of the emissions of sulfur oxides and nitrogen oxides from barges. The composting of horticultural wastes hardly imposes any environmental damage. Out of all the waste strategies, the recycling of wastes offers the best solution for environmental protection and improved human health for the nation. Significant emission savings can be realized through recycling. PMID:16573187

  3. Management options for sphincteric deficiency in adults with neurogenic bladder

    PubMed Central

    Mayer, Erik N.; Lenherr, Sara

    2016-01-01

    Neurogenic bladder is a very broad disease definition that encompasses varied disease and injury states affecting the bladder. The majority of patients with neurogenic bladder dysfunction do not have concomitant intrinsic sphincteric deficiency (ISD), but when this occurs the challenges of management of urinary incontinence from neurogenic bladder are compounded. There are no guidelines for surgical correction of ISD in adults and most of the literature on treatment of the problem comes from treatment of children with congenital diseases, such as myelomeningocele. Our goal, in this review, is to present some of the common surgical options for ISD [including artificial urinary sphincters, bladder slings, bladder neck reconstruction (BNR) and urethral bulking agents] and the evidence underlying these treatments in adults with neurogenic bladder. PMID:26904420

  4. Treatment options for the management of pervasive developmental disorders.

    PubMed

    Nash, Kathryn; Carter, K Jennifer

    2016-01-01

    Autism spectrum disorder (previously known as pervasive developmental disorders) is characterized by social communication deficits, impaired functioning, and restrictive or repetitive behaviors and interests. Patients with autism spectrum disorder also commonly experience core maladaptive behaviors such as aggression and irritability, self-injurious behaviors, hyperactivity, and sleep abnormalities. These behaviors may be sources of stress for caregivers and patients alike and may require pharmacologic management. Risperidone and aripiprazole are frequently used to treat both irritability and self-injurious behavior related to autism spectrum disorder. The opioid antagonist naltrexone has also been studied for self-injurious behaviors, although long-term data are lacking when used in the autism spectrum disorder population. Methylphenidate, atomoxetine, clonidine, and guanfacine are all potential options for the treatment of hyperactivity or attention-deficient hyperactivity disorder-like symptoms in patients with autism spectrum disorder. Lastly, melatonin is the most widely researched medication strategy for the management of sleep disorders in autism spectrum disorder. Future studies reviewing new pharmacologic treatment approaches in combination with non-pharmacologic therapies are warranted to ensure that target behaviors of autism spectrum disorder are appropriately managed. PMID:27079778

  5. Management of primary cicatricial alopecias: options for treatment.

    PubMed

    Harries, M J; Sinclair, R D; Macdonald-Hull, S; Whiting, D A; Griffiths, C E M; Paus, R

    2008-07-01

    Primary cicatricial alopecias (PCAs) are a poorly understood group of disorders that result in permanent hair loss. Clinically, they are characterized not only by permanent loss of hair shafts but also of visible follicular ostia along with other visible changes in skin surface morphology, while their histopathological hallmark usually (although not always) is the replacement of follicular structures with scar-like fibrous tissue. As hair follicle neogenesis in adult human scalp skin is not yet a readily available treatment option for patients with cicatricial alopecias, the aim of treatment, currently, remains to reduce symptoms and to slow or stop PCA progression, namely the scarring process. Early treatment is the key to minimizing the extent of permanent alopecia. However, inconsistent terminology, poorly defined clinical end-points and a lack of good quality clinical trials have long made management of these conditions very challenging. As one important step towards improving the management of this under-investigated and under-serviced group of dermatoses, the current review presents evidence-based guidance for treatment, with identification of the strength of evidence, and a brief overview of clinical features of each condition. Wherever only insufficient evidence-based advice on PCA management can be given at present, this is indicated so as to highlight important gaps in our clinical knowledge that call for concerted efforts to close these in the near future. PMID:18489608

  6. LANDFILL GAS ENERGY UTILIZATION: TECHNOLOGY OPTIONS AND CASE STUDIES

    EPA Science Inventory

    The report discusses technical, environmental, and other issues associated with using landfill gas as fuel, and presents case studies of projects in the U.S. illustrating some common energy uses. he full report begins by covering basic issues such as gas origin, composition, and ...

  7. Integrated Analysis of Greenhouse Gas Mitigation Options and Related Impacts

    EPA Science Inventory

    Increased concerns over air pollution (combined with detrimental health effects) and climate change have called for more stringent emission reduction strategies for criteria air pollutants and greenhouse gas emissions. However, stringent regulatory policies can possibly have a...

  8. Participatory groundwater management in Jordan: Development and analysis of options

    NASA Astrophysics Data System (ADS)

    Chebaane, Mohamed; El-Naser, Hazim; Fitch, Jim; Hijazi, Amal; Jabbarin, Amer

    Groundwater over-exploitation has been on the rise in Jordan. Competing demands have grown in the face of perennial water shortages, a situation which has been exacerbated by drought conditions in the past decade. This paper reports findings of a project in which management options to address over-exploitation were developed for one of Jordan's principal aquifer systems, the Amman-Zarqa Basin. Options for addressing the situation were developed through a participatory approach that involved government officials and various public and private sector interest groups. Particular efforts were made to involve well irrigators, who are likely to be heavily impacted by the changes required to reduce groundwater pumping to a sustainable level. With information obtained from a rapid appraisal survey as well as from interviews with farmers, community groups, government officials, and technical experts, an extensive set of options was identified for evaluation. Based on integrated hydrogeologic, social, and economic analysis, five complementary management options were recommended for implementation. These included the establishment of an Irrigation Advisory Service, buying out farm wells, placing firm limits on well ion and irrigated crop areas, exchanging treated wastewater for groundwater, and measures to increase the efficiency of municipal and industrial water use. Various combinations and levels of these options were grouped in scenarios, representing possible implementation strategies. The scenarios were designed to assist decision makers, well owners and other stakeholders in moving gradually towards a sustainable ion regime. Social and economic aspects of each option and scenario were analyzed and presented to stakeholders, together with a of legal, institutional and environmental ramifications. Combining scientific analysis with a participatory approach in the Amman Zarqa Basin groundwater management was devised as a prototype to be used in the management of other

  9. Reservoir management options for improving water productivity in Africa

    NASA Astrophysics Data System (ADS)

    Niasse, M.

    2003-04-01

    Although there seems to be a global consensus on the need for improving the productivity of water, little progress has been made, especially in Africa, toward applying this concept in approaches to water resources planning and management. The notion of water productivity refers to the types, amount and value of material and non material products generated from water use, and embraces therefore a broad spectrum outputs, including crop and hydropower production, livestock and fishery yields, as well as outputs from other water-based activities such as domestic and industrial water consumption. In contexts of water scarcity, like in many regions in Africa, it becomes more and more important to allocate available freshwater resources among competing sectors as efficiently as possible, while taking into account the needs of aquatic ecosystems and the concerns of equity and poverty reduction. A minimum level of control of water is often necessary for the implementation of these water allocation principles. On the basis of the water budget of the Senegal River -- a basin where a significant share of the river flow is controlled by dams since the late 1980s—and other river basins in Africa, the proposed communication analyses the merits and limitations of different reservoir management options. On this basis the paper discuss approaches to optimal and sustainable water allocation which takes into consideration multiple uses and the need for greater equity in access and reduced vulnerability of the poor.

  10. Bilateral diaphragmatic palsy after congenital heart surgery: management options.

    PubMed

    Bhaskar, Pradeep; Lone, Reyaz A; Sallehuddin, Ahmad; John, Jiju; Bhat, Akhlaque N; Rahmath, Muhammed R K

    2016-06-01

    Diaphragmatic paralysis following phrenic nerve injury is a major complication following congenital cardiac surgery. In contrast to unilateral paralysis, patients with bilateral diaphragmatic paralysis present a higher risk group, require different management methods, and have poorer prognosis. We retrospectively analysed seven patients who had bilateral diaphragmatic paralysis following congenital heart surgery during the period from July, 2006 to July, 2014. Considerations were given to the time to diagnosis of diaphragm paralysis, total ventilator days, interval after plication, and lengths of ICU and hospital stays. The incidence of bilateral diaphragmatic paralysis was 0.68% with a median age of 2 months (0.6-12 months). There was one neonate and six infants with a median weight of 4 kg (3-7 kg); five patients underwent unilateral plication of the paradoxical diaphragm following recovery of the other side, whereas the remaining two patients who did not demonstrate a paradoxical movement were successfully weaned from the ventilator following recovery of function in one of the diaphragms. The median ventilation time for the whole group was 48 days (20-90 days). The median length of ICU stay was 46 days (24-110 days), and the median length of hospital stay was 50 days (30-116 days). None of the patients required tracheostomy for respiratory support and there were no mortalities, although all the patients except one developed ventilator-associated pneumonia. The outcome of different management options for bilateral diaphragmatic paralysis following surgery for CHD is discussed. PMID:26345716

  11. High Temperature Gas-Cooled Test Reactor Options Status Report

    SciTech Connect

    Sterbentz, James William; Bayless, Paul David

    2015-08-01

    Preliminary scoping calculations are being performed for a 100 MWt gas-cooled test reactor. The initial design uses standard prismatic blocks and 15.5% enriched UCO fuel. Reactor physics and thermal-hydraulics simulations have been performed to identify some reactor design features to investigate further. Current status of the effort is described.

  12. Greenhouse Gas Management Program Overview (Fact Sheet)

    SciTech Connect

    Not Available

    2011-11-01

    Program fact sheet highlighting federal requirements for GHG emissions management, FEMP services to help agencies reduce emissions, and additional resources. The U.S. Department of Energy (DOE) Federal Energy Management Program (FEMP) assists Federal agencies with managing their greenhouse gas (GHG) emissions. GHG management entails measuring emissions and understanding their sources, setting a goal for reducing emissions, developing a plan to meet this goal, and implementing the plan to achieve reductions in emissions. FEMP provides the following services to help Federal agencies meet the requirements of inventorying and reducing their GHG emissions: (1) FEMP offers one-on-one technical assistance to help agencies understand and implement the Federal Greenhouse Gas Accounting and Reporting Guidance and fulfill their inventory reporting requirements. (2) FEMP provides training, tools, and resources on FedCenter to help agencies complete their annual inventories. (3) FEMP serves a leadership role in the interagency Federal Working Group on Greenhouse Gas Accounting and Reporting that develops recommendations to the Council on Environmental Quality (CEQ) for the Federal Greenhouse Gas Accounting and Reporting Guidance. (4) As the focus continues to shift from measuring emissions (completing inventories) to mitigating emissions (achieving reductions), FEMP is developing a strategic planning framework and resources for agencies to prioritize among a variety of options for mitigating their GHG emissions, so that they achieve their reduction goals in the most cost-effective manner. These resources will help agencies analyze their high-quality inventories to make strategic decisions about where to use limited resources to have the greatest impact on reducing emissions. Greenhouse gases trap heat in the lower atmosphere, warming the earth's surface temperature in a natural process known as the 'greenhouse effect.' GHGs include carbon dioxide (CO{sub 2}), methane (CH{sub 4

  13. Thermal management technology for hydrogen storage: Fullerene option

    SciTech Connect

    Wang, J.C.; Chen, F.C.; Murphy, R.W.

    1996-10-01

    Fullerenes are selected as the first option for investigating advanced thermal management technologies for hydrogen storage because of their potentially high volumetric and gravimetric densities. Experimental results indicate that about 6 wt% of hydrogen (corresponding to C{sub 60}H{sub 48}) can be added to and taken out of fullerenes. A model assuming thermally activated hydrogenation and dehydrogenation processes was developed to explain the experimental findings. The activation energies were estimated to be 100 and 160 kJ/mole (1.0 and 1.6 eV/H{sub 2}) for the hydrogenation and dehydrogenation processes, respectively. The difference is interpreted as the heat released during hydrogenation. There are indications that the activation energies and the heat of hydrogenation can be modified by the use of catalysts. Preliminary hydrogen storage simulations for a conceptually simple device were performed. A 1-m long hollow metal cylinder with an inner diameter of 0.02 m was assumed to be filled with fullerene powders. The results indicate that the thermal diffusivity of the fullerenes controls the hydrogenation and dehydrogenation rates. The rates can be significantly modified by changing the thermal diffusivity of the material inside the cylinder, e.g., by incorporating a metal mesh. Results from the simulation suggest that thermal management is essential for efficient hydrogen storage devices using fullerenes. While the preliminary models developed in this study explain some of the observation, more controlled experiments, rigorous model development, and physical property determinations are needed for the development of practical hydrogen storage devices. The use of catalysts to optimize the hydrogen storage characteristics of fullerenes also needs to be pursued. Future cooperative work between Oak Ridge National Laboratory (ORNL) and Material & Electrochemical Research Corporation (MER) is planned to address these needs.

  14. RealGasBrine v1.0 option of TOUGH+ v1.5

    SciTech Connect

    Moridis, George

    2015-02-27

    RealGasBrine v1.0 is a numerical code that for the simulation of the behavior of gas-bearing porous and/fractured geologic media. It is an option of TOUGH+ v1.5 [Moridis, 2014], a successor to the TOUGH2 [Pruess et al., 1999; 2012] family of codes for multi-component, multiphase ?uid and heat ?ow developed at the Lawrence Berkeley National Laboratory. RealGasBrine v1.0 needs the TOUGH+ v1.5 core code in order to compile and execute. It is written in standard FORTRAN 95/2003, and can be run on any computational platform (workstation, PC, Macintosh) for which such compilers are available. RealGasBrine v1.0 describes the non-isothermal two- (for pure water) or three-phase (for brine) flow of an aqueous phase and a real gas mixture in a gas-bearing medium, with a particular focus in ultra-tight (such as tight-sand and shale gas) systems. Up to 12 individual real gases can be tracked, and salt can precipitate as solid halite. The capabilities of the code include coupled flow and thermal effects, real gas behavior, Darcy and non-Darcy flow, several isotherm options of gas sorption onto the grains of the porous media, complex fracture descriptions, gas solubility into water, and geomechanical effects on flow properties. RealGasBrine v1.0 allows the study of flow and transport of fluids and heat over a wide range of time frames and spatial scales not only in gas reservoirs, but also in any problem involving the flow of gases in geologic media, including the geologic storage of greenhouse gas mixtures, the behavior of geothermal reservoirs with multi-component condensable (H2O and CO2) and non-condensable gas mixtures, the transport of water and released H2 in nuclear waste storage applications, etc.

  15. Analysis of options for management of spent Stretford solution. [Purge of Stretford solution

    SciTech Connect

    Tallon, J.T.; Rittmeyer, R.W.; Maruhnich, E.D.

    1984-06-01

    During each cycle of the Stretford process a small percentage of the sulfide present in the feed gas is irreversibly converted to thiosulfate and sulfate, and cyanide is irreversibly convertd to thiocyanate. The accumulation of sulfates in the Stretford solution reduces the solubility of the active Stretford chemicals (i.e., sodium vanadate and anthraquinone-disulfonic acid (ADA)). This decreases the rate of oxidative regeneration. To maintain the thiosulfate, sulfate and thiocyanate concentrations at acceptable levels, a continuous purge, or blowdown, of the Stretford solution is required. The continuous purge of Stretford solution results in a loss of active chemicals which must be replaced and ultimately increases Stretford operating costs. In addition, the blowdown must be reclaimed, treated, and/or disposed which also adds to the operating costs. This report presents an analysis of waste-management alternatives for handling the blowdown stream produced from the Stretford process. The objective of this study is to evaluate the relative economics of the most promising alternatives available for managing spent Stretford solution by comparing technical feasibility, performance, and costs associated with the alternatives. The available Stretford solution-characterization data and waste-management options were identified by reviewing literature sources. The waste-management options identified were then screened based on technical, economic and environmental criteria to identify the most promising set of alternatives. Finally, a comparative economic analysis was performed on the most promising set of alternatives using the Stretford process at the Great Plains Gasification Associates (GPGA) facilty as the basis for comparison. 23 refs., 5 figs., 29 tabs.

  16. A multi-criteria decision analysis assessment of waste paper management options

    SciTech Connect

    Hanan, Deirdre; Burnley, Stephen; Cooke, David

    2013-03-15

    Highlights: ► Isolated communities have particular problems in terms of waste management. ► An MCDA tool allowed a group of non-experts to evaluate waste management options. ► The group preferred local waste management solutions to export to the mainland. ► Gasification of paper was the preferred option followed by recycling. ► The group concluded that they could be involved in the decision making process. - Abstract: The use of Multi-criteria Decision Analysis (MCDA) was investigated in an exercise using a panel of local residents and stakeholders to assess the options for managing waste paper on the Isle of Wight. Seven recycling, recovery and disposal options were considered by the panel who evaluated each option against seven environmental, financial and social criteria. The panel preferred options where the waste was managed on the island with gasification and recycling achieving the highest scores. Exporting the waste to the English mainland for incineration or landfill proved to be the least preferred options. This research has demonstrated that MCDA is an effective way of involving community groups in waste management decision making.

  17. CONCEPTUAL APPROACHES FOR INCORPORATING CLIMATIC CHANGE INTO THE DEVELOPMENT OF FOREST MANAGEMENT OPTIONS FOR SEQUESTERING CARBON

    EPA Science Inventory

    The potential for significant environmental change over the next 100 years has resulted in efforts to develop mitigation options for reducing the rate of increase of carbon dioxide concentrations in the atmosphere. ne of the more promising options is management of forest and agro...

  18. Management Options For Reducing The Release Of Antibiotics And Antibiotic Resistance Genes To The Environment

    EPA Science Inventory

    Background: There is growing concern worldwide about the role of polluted soil and water - 77 environments in the development and dissemination of antibiotic resistance. 78 Objective: To identify management options for reducing the spread of antibiotics and 79 antibiotic resist...

  19. Modern management of adult coarctation: transcatheter and surgical options.

    PubMed

    Schneider, Heiko; Uebing, Anselm; Shore, Darryl F

    2016-08-01

    Coarctation of the aorta (CoA), a juxtaductal obstructive lesion in the descending aorta and commonly associated with hypoplasia of the aortic arch occurs in 5-8% of patients with congenital heart disease. Since the initial surgical corrections in the 1950, surgical and transcatheter options have constantly evolved. Nowadays, transcatheter options are widely accepted as the initial treatment of choice in adults presenting with native or recurrent CoA. Surgical techniques are mainly reserved for patients with complex aortic arch anatomy such as extended arch hypoplasia or stenosis or para-CoA aneurysm formation. Extended aneurysms can be covered by conformable stents but stent implantation may require preparative vascular surgery. Complex re-CoA my best be treated by an ascending to descending bypass conduit. The following review aims to describe current endovascular and surgical practice pointing out modern developments and their limitations. PMID:27243624

  20. An integrated assessment of options for rural wastewater management in Austria.

    PubMed

    Starkl, M; Ornetzeder, M; Binner, E; Holubar, P; Pollak, M; Dorninger, M; Mascher, F; Fuerhacker, M; Haberl, R

    2007-01-01

    This paper reports a recently finished, interdisciplinary project on rural wastewater management in Austria. The objective of the project was to study alternative wastewater management options based on separation of the wastewater into its constituent parts, and to compare them with conventional ones. Thereby, a feasibility study of both conventional and alternative options for wastewater management in six model regions was carried out. Life cycle costs and social acceptance were analysed by using a case study-based assessment approach. However, hygienic and environmental risks were evaluated on a more general level. In order to complement the findings, a survey on urine separation system users in the Solar City of Linz was conducted. Based on these assessments and empirical findings, the paper concludes that options using a full separation of all wastewater fractions should be considered with care. Options based on a separation of only grey water and black water or in the liquid/solid phase can offer ecological and financial advantages over conventional options. Further, options combining wastewater management and regional biogas plants were identified as an interesting solution. However, legal constraints restrict this option currently. PMID:17881843

  1. Membrane Distillation Bioreactor (MDBR) - A lower Green-House-Gas (GHG) option for industrial wastewater reclamation.

    PubMed

    Goh, Shuwen; Zhang, Jinsong; Liu, Yu; Fane, Anthony G

    2015-12-01

    A high-retention membrane bioreactor system, the Membrane Distillation Bioreactor (MDBR) is a wastewater reclamation process which has the potential to tap on waste heat generated in industries to produce high quality product water. There are a few key factors which could make MDBR an attractive advanced treatment option, namely tightening legal requirements due to increasing concerns on the micropollutants in industrial wastewater effluents as well as concerns over the electrical requirement of pressurized advanced treatment processes and greenhouse gas emissions associated with wastewater reclamation. This paper aims to provide a consolidated review on the current state of research for the MDBR system and to evaluate the system as a possible lower Green House Gas (GHG) emission option for wastewater reclamation using the membrane bioreactor-reverse osmosis (MBR-RO) system as a baseline for comparison. The areas for potential applications and possible configurations for MDBR applications are discussed. PMID:25262945

  2. RealGasBrine v1.0 option of TOUGH+ v1.5

    Energy Science and Technology Software Center (ESTSC)

    2015-02-27

    RealGasBrine v1.0 is a numerical code that for the simulation of the behavior of gas-bearing porous and/fractured geologic media. It is an option of TOUGH+ v1.5 [Moridis, 2014], a successor to the TOUGH2 [Pruess et al., 1999; 2012] family of codes for multi-component, multiphase ?uid and heat ?ow developed at the Lawrence Berkeley National Laboratory. RealGasBrine v1.0 needs the TOUGH+ v1.5 core code in order to compile and execute. It is written in standard FORTRANmore » 95/2003, and can be run on any computational platform (workstation, PC, Macintosh) for which such compilers are available. RealGasBrine v1.0 describes the non-isothermal two- (for pure water) or three-phase (for brine) flow of an aqueous phase and a real gas mixture in a gas-bearing medium, with a particular focus in ultra-tight (such as tight-sand and shale gas) systems. Up to 12 individual real gases can be tracked, and salt can precipitate as solid halite. The capabilities of the code include coupled flow and thermal effects, real gas behavior, Darcy and non-Darcy flow, several isotherm options of gas sorption onto the grains of the porous media, complex fracture descriptions, gas solubility into water, and geomechanical effects on flow properties. RealGasBrine v1.0 allows the study of flow and transport of fluids and heat over a wide range of time frames and spatial scales not only in gas reservoirs, but also in any problem involving the flow of gases in geologic media, including the geologic storage of greenhouse gas mixtures, the behavior of geothermal reservoirs with multi-component condensable (H2O and CO2) and non-condensable gas mixtures, the transport of water and released H2 in nuclear waste storage applications, etc.« less

  3. Coalbed methane-produced water quality and its management options in Raniganj Basin, West Bengal, India

    NASA Astrophysics Data System (ADS)

    Mendhe, Vinod Atmaram; Mishra, Subhashree; Varma, Atul Kumar; Singh, Awanindra Pratap

    2015-09-01

    Coalbed methane (CBM) recovery is associated with production of large quantity of groundwater. The coal seams are depressurized by pumping of water for regular and consistent gas production. Usually, CBM operators need to pump >10 m3 of water per day from one well, which depends on the aquifer characteristics, drainage and recharge pattern. In India, 32 CBM blocks have been awarded for exploration and production, out of which six blocks are commercially producing methane gas at 0.5 million metric standard cubic feet per day. Large amount of water is being produced from CBM producing blocks, but no specific information or data are available for geochemical properties of CBM-produced water and its suitable disposal or utilization options for better management. CBM operators are in infancy and searching for the suitable solutions for optimal management of produced water. CBM- and mine-produced water needs to be handled considering its physical and geochemical assessment, because it may have environmental as well as long-term impact on aquifer. Investigations were carried out to evaluate geochemical and hydrogeological conditions of CBM blocks in Raniganj Basin. Totally, 15 water samples from CBM well head and nine water samples from mine disposal head were collected from Raniganj Basin. The chemical signature of produced water reveals high sodium and bicarbonate concentrations with low calcium and magnesium, and very low sulphate in CBM water. It is comprehend that CBM water is mainly of Na-HCO3 type and coal mine water is of Ca-Mg-SO4 and HCO3-Cl-SO4 type. The comparative studies are also carried out for CBM- and mine-produced water considering the geochemical properties, aquifer type, depth of occurrence and lithological formations. Suitable options like impounding, reverse osmosis, irrigation and industrial use after prerequisite treatments are suggested. However, use of this huge volume of CBM- and mine-produced water for irrigation or other beneficial purposes

  4. Study of investigation-derived waste management options. Master's thesis

    SciTech Connect

    Mountain, B.C.

    1993-09-01

    USAF is dedicated to the clean up of past releases of hazardous substances at its bases under the Installation Restoration Program (IRP) . Clean up decisions are based upon data produced from investigations. Large amounts of waste may be derived from investigations. Investigation-derived waste (IDW), especially that with a hazardous component, may pose significant health protection and regulatory compliance problems if neglected. This study identifies the status and the need for improvement of IDW management to avoid those problems. Information on the background of IDW management was collected through a review of environmental laws, waste management regulations, and existing guidance. Practical IDW management information was gleaned from conversations with iRP managers at twelve USAF bases around the country. This study revealed that IDW management needs improvement. All bases acknowledged IDW concerns and have adopted various methods to deal with them. However, current methods appear to rely more upon expediency rather than permanence. This study showed that critical protection and compliance issues are being overlooked. Development of specific IDW management guidance may better assure that critical issues are addressed. Waste minimization, Waste management, Environmental management, Nonhazardous wastes, Hazardous material, Solid wastes.

  5. Greenhouse gas emissions from a managed grassland

    NASA Astrophysics Data System (ADS)

    Jones, S. K.; Rees, R. M.; Skiba, U. M.; Ball, B. C.

    2005-07-01

    Managed grasslands contribute to global warming by the exchange of the greenhouse gases carbon dioxide, nitrous oxide and methane. To reduce uncertainties of the global warming potential of European grasslands and to assess potential mitigation options, an integrated approach quantifying fluxes from all three gases is needed. Greenhouse gas emissions from a grassland site in the SE of Scotland were measured in 2002 and 2003. Closed static chambers were used for N 2O and CH 4 flux measurements, and samples were analysed by gas chromatography. Closed dynamic chambers were used for soil respiration measurements, using infrared gas analysis. Three organic manures and two inorganic fertilizers were applied at a rate of 300 kg N ha -1 a -1 (available N) and compared with a zero-N control on grassland plots in a replicated experimental design. Soil respiration from plots receiving manure was up to 1.6 times larger than CO 2 release from control plots and up to 1.7 times larger compared to inorganic treatments ( p<0.05). A highly significant ( p<0.001) effect of fertilizer and manure treatments on N 2O release was observed. Release of N 2O from plots receiving inorganic fertilizers resulted in short term peaks of up to 388 g N 2O-N ha -1 day -1. However losses from plots receiving organic manures were both longer lasting and greater in magnitude, with an emission of up to 3488 g N 2O-N ha -1 day -1 from the sewage sludge treatments. During the 2002 growing season the cumulative total N 2O flux from manure treatments was 25 times larger than that from mineral fertilizers. CH 4 emissions were only significantly increased ( p<0.001) for a short period following applications of cattle slurry. Although soil respiration in manure plots was high, model predictions and micrometeorological flux measurements at an adjacent site suggest that all plots receiving fertilizer or manure acted as a sink for CO 2. Therefore in terms of global warming potentials the contribution of N 2O from

  6. Options for Managing Student Behavior: Adaptations for Individual Needs.

    ERIC Educational Resources Information Center

    Richardson, Rita C.; Evans, Elizabeth T.

    This paper applies principles of situational leadership theory to the management of student behavior problems. First, it summarizes situational leadership, noting the theory's premise that leaders must consider two important factors to gain acceptance and compliance in managing people--the maturity level of the individuals and the nature of the…

  7. Therapeutic options for the management of pancreatic cancer

    PubMed Central

    Rossi, Maria L; Rehman, Azeem A; Gondi, Christopher S

    2014-01-01

    Since its initial characterization, pancreatic ductal adenocarcinoma has remained one of the most devastating and difficult cancers to treat. Pancreatic cancer is the fourth leading cause of death in the United States, resulting in an estimated 38460 deaths annually. With few screening tools available to detect this disease at an early stage, 94% of patients will die within five years of diagnosis. Despite decades of research that have led to a better understanding of the molecular and cellular signaling pathways in pancreatic cancer cells, few effective therapies have been developed to target these pathways. Other treatment options have included more sophisticated pancreatic cancer surgeries and combination therapies. While outcomes have improved modestly for these patients, more effective treatments are desperately needed. One of the greatest challenges in the future of treating this malignancy will be to develop therapies that target the tumor microenvironment and surrounding pancreatic cancer stem cells in addition to pancreatic cancer cells. Recent advances in targeting pancreatic stellate cells and the stroma have encouraged researchers to shift their focus to the role of desmoplasia in pancreatic cancer pathobiology in the hopes of developing newer-generation therapies. By combining novel agents with current cytotoxic chemotherapies and radiation therapy and personalizing them to each patient based on specific biomarkers, the goal of prolonging a patient’s life could be achieved. Here we review the most effective therapies that have been used for the treatment of pancreatic cancer and discuss the future potential of therapeutic options. PMID:25170201

  8. Options and opportunities for clinical management and treatment of psoriasis.

    PubMed

    Agrawal, Udita; Gupta, Madhu; Dube, Devyani; Vyas, Suresh P

    2013-01-01

    Psoriasis is a complex, multifactorial disease that appears to be influenced by immune-mediated components. For many years the pathogenesis of psoriasis has been discordant; the clinical picture suggested that the psoriasis was secondary to abnormal keratinocyte proliferation and differentiation, but later the role of the T cell was revealed. A variety of treatment options range from topical agents (e.g., coal tar, dithranol, and emollients for milder forms) to systemic agents (i.e., methotrexate or cyclosporin), and phototherapy. Recently, biologics have been added to this list that target particular steps in the immune or inflammatory pathways. Various nanocarriers (e.g., liposomes, niosomes, and microemulsions) have been successfully exploited for the delivery of several antipsoriatic drugs. This review provides insight into various psoriasis treatment strategies-from conventional to novel-currently in use or in development as well as the novel targets that have been explored and/or investigated for anti-psoriatic therapy. The pathogenesis of psoriasis and some of the topical, systemic biological, and novel approaches currently in use or in development are reviewed here. The pros and cons of each treatment strategy are presented, as are some of the animal models used to study features reminiscent of psoriasis. This information can be used to better the understanding of treatment options for this disease. PMID:23510110

  9. Rice management interventions to mitigate greenhouse gas emissions: a review.

    PubMed

    Hussain, Saddam; Peng, Shaobing; Fahad, Shah; Khaliq, Abdul; Huang, Jianliang; Cui, Kehui; Nie, Lixiao

    2015-03-01

    Global warming is one of the gravest threats to crop production and environmental sustainability. Rice, the staple food of more than half of the world's population, is the most prominent cause of greenhouse gas (GHG) emissions in agriculture and gives way to global warming. The increasing demand for rice in the future has deployed tremendous concerns to reduce GHG emissions for minimizing the negative environmental impacts of rice cultivation. In this review, we presented a contemporary synthesis of existing data on how crop management practices influence emissions of GHGs in rice fields. We realized that modifications in traditional crop management regimes possess a huge potential to overcome GHG emissions. We examined and evaluated the different possible options and found that modifying tillage permutations and irrigation patterns, managing organic and fertilizer inputs, selecting suitable cultivar, and cropping regime can mitigate GHG emissions. Previously, many authors have discussed the feasibility principle and the influence of these practices on a single gas or, in particular, in the whole agricultural sector. Nonetheless, changes in management practices may influence more than one gas at the same time by different mechanisms or sometimes their effects may be antagonistic. Therefore, in the present attempt, we estimated the overall global warming potential of each approach to consider the magnitude of its effects on all gases and provided a comprehensive assessment of suitable crop management practices for reducing GHG emissions in rice culture. PMID:25354441

  10. CAD/CAM data management needs, requirements and options

    NASA Technical Reports Server (NTRS)

    Lopatka, R. S.; Johnson, T. G.

    1978-01-01

    The requirements for a data management system in support of technical or scientific applications and possible courses of action were reviewed. Specific requirements were evolved while working towards higher level integration impacting all phases of the current design process and through examination of commercially marketed systems and related data base research. Arguments are proposed for varied approaches in implementing data base systems ranging from no action necessary to immediate procurement of an existing data base management system.

  11. Managing oil disruptions: issues and policy options. [Monograph

    SciTech Connect

    Webre, P.

    1981-01-01

    The Congressional Budget Office (CBO) prepared the analysis of policy options to help Congress decide whether to extend or expand the Emergency Petroleum Allocation Act of 1973, or whether to let it lapse on September 30, 1981. The central theme is that large disruptions of imported oil can deal the economy a severe blow that reduces output and increases unemployment and inflation. Alternative policies might allow this blow to be offset in different ways, but they cannot eliminate an impact. Some policies better contain the inflationary effects of a disruption, but are less effective in mitigating losses in aggregate production and higher unemployment. For others, the converse is true. Further, the appropriateness of each policy varies with the size and anticipated duration of the import disruption. Congress may wish to consider a portfolio of standby policies as well as the selection of just one. Two appendices offer further policy analyses. 10 references, 3 tables.

  12. Options for treating high-temperature gas-cooled reactor fuel for repository disposal

    SciTech Connect

    Lotts, A.L.; Bond, W.D.; Forsberg, C.W.; Glass, R.W.; Harrington, F.E.; Micheals, G.E.; Notz, K.J.; Wymer, R.G.

    1992-02-01

    This report describes the options that can reasonably be considered for disposal of high-temperature gas-cooled reactor (HTGR) fuel in a repository. The options include whole-block disposal, disposal with removal of graphite (either mechanically or by burning), and reprocessing of spent fuel to separate the fuel and fission products. The report summarizes what is known about the options without extensively projecting or analyzing actual performance of waste forms in a repository. The report also summarizes the processes involved in convert spent HTGR fuel into the various waste forms and projects relative schedules and costs for deployment of the various options. Fort St. Vrain Reactor fuel, which utilizes highly-enriched {sup 235}U (plus thorium) and is contained in a prismatic graphite block geometry, was used as the baseline for evaluation, but the major conclusions would not be significantly different for low- or medium-enriched {sup 235}U (without thorium) or for the German pebble-bed fuel. Future US HTGRs will be based on the Fort St. Vrain (FSV) fuel form. The whole block appears to be a satisfactory waste form for disposal in a repository and may perform better than light-water reactor (LWR) spent fuel. From the standpoint of process cost and schedule (not considering repository cost or value of fuel that might be recycled), the options are ranked as follows in order of increased cost and longer schedule to perform the option: (1) whole block, (2a) physical separation, (2b) chemical separation, and (3) complete chemical processing.

  13. Middle ear capillary haemangioma: Review of literature and appraisal of management options.

    PubMed

    Salamat, Ali A; Casselden, Elizabeth; Theaker, Jeffrey; Batty, Vincent; Thomas, Sebastian

    2016-12-01

    Infantile middle ear capillary haemangiomas (MECH) are a rare entity with only five reported cases in the literature. At present there is no consensus regarding the management of such lesions. Extra-cutaneous haemangiomas have been successfully managed with oral propranolol but not yet reported in MECH. We present a further case and appraise the management options. At present oral propranolol has not been used in the treatment of MECH. The literature suggests that infantile MECH have a higher propensity to spontaneously involute and a greater likelihood of response to propranolol. Surgical excision is the best option in older children and adults. PMID:26992272

  14. PHILADELPHIA AIR TOXICS STUDY: EVALUATION OF RISK MANAGEMENT OPTIONS USING MIRA

    EPA Science Inventory

    Evaluation of risk management options usually takes place within single programs at the U.S. EPA. This can produce inadvertent tradeoffs among important criteria by risk managers and other decision makers; resulting in decision surprises. This study is a demonstration of a diff...

  15. How to manage fatigue in fibromyalgia: nonpharmacological options.

    PubMed

    Ericsson, Anna; Mannerkorpi, Kaisa

    2016-05-01

    The aim of this article is to suggest recommendations for the management of fatigue in fibromyalgia (FM) by reviewing and compiling findings of nonpharmacological treatment for fatigue in patients with FM. The management of fatigue in FM should incorporate regular physical exercise maintained for a longer period of time, which contributes to improved general health and facilitates coping with fatigue and other symptoms. The evidence is still low and the effect of exercise on fatigue in FM needs to be further studied. Patients with FM appear to benefit from general sleep hygiene advice and also need to develop individual strategies to manage the complex factors in everyday life that may be related to fatigue. PMID:27297077

  16. An alternative option in the management of blunt splenic injury

    PubMed Central

    Bodansky, David; Jones, Robert; Tucker, Olga N.

    2013-01-01

    Splenic injury is a preventable cause of mortality following blunt trauma. The majority of splenic injuries can be managed conservatively. Laparotomy is indicated in the haemodynamically unstable patient, or those with other intra-abdominal injuries requiring surgery. Angio-embolization can be used to achieve haemostasis and preserve splenic parenchyma. The expertise and experience of the multidisciplinary trauma team and resources of the receiving facility are critical in determining the optimal management approach. We present a patient with a successful outcome following selective angio-embolization for ongoing bleeding from a Grade 4 splenic injury. PMID:24964468

  17. New Fuel Cycle and Fuel Management Options in Heavy Liquid Metal-Cooled Reactors

    SciTech Connect

    Greenspan, Ehud; Hejzlar, Pavel; Sekimoto, Hiroshi; Toshinsky, Georgy; Wade, David

    2005-08-15

    Fast reactors cooled by lead or lead-bismuth alloy offer new interesting fuel cycle and fuel management options by virtue of the superb neutronics and safety features of these heavy liquid metal (HLM) coolants. One option is once-for-life cores having relatively low power density. These cores are fueled in the factory; there is no refueling or fuel shuffling on site. A second option is very long-life cores being made of a fissioning zone and a natural uranium blanket zone. The fissioning zone very slowly drifts toward the blanket. A third option is multirecycling of light water reactor (LWR) discharged fuel without partitioning of transuranics (TRUs) in fuel-self-sustaining reactors. LWR spent fuel could provide the initial fuel loading after extracting fission products and {approx}90% of its uranium. The makeup fuel is natural or depleted uranium. A fourth option is the high-burnup once-through fuel cycle using natural or depleted uranium feed. The initial fuel loading of this reactor is a mixture of enriched and natural uranium. The natural uranium utilization is 10 to 20 times higher than that of a once-through LWR. A fifth option is transmutation of TRUs from LWRs using critical HLM-cooled reactors; such reactors could be designed to have the same high actinide burning capability of accelerator-driven systems and have comparable safety, but at a substantially lower cost. These novel reactor designs and fuel management options are hereby reviewed.

  18. ANALYSIS OF INSECT RESISTANCE MANAGEMENT OPTIONS FOR TRANSGENIC BT CORN,

    EPA Science Inventory

    Increasing interest in the responsible management of technology in the industrial and agricultural sectors of the economy has been met through the development of broadly applicable tools to assess the "sustainability" of new technologies. An arena ripe for application of such ana...

  19. Agricultural management options for climate variability and change: conservation tillage

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Adapting to climate variability and change can be achieved through a broad range of management alternatives and technological advances. This publication is focused on the use of conservation tillage in crop production systems. The publication outlines ways that conservation tillage can reduce risk r...

  20. Water management practices used by Fayetteville shale gas producers.

    SciTech Connect

    Veil, J. A.

    2011-06-03

    Water issues continue to play an important role in producing natural gas from shale formations. This report examines water issues relating to shale gas production in the Fayetteville Shale. In particular, the report focuses on how gas producers obtain water supplies used for drilling and hydraulically fracturing wells, how that water is transported to the well sites and stored, and how the wastewater from the wells (flowback and produced water) is managed. Last year, Argonne National Laboratory made a similar evaluation of water issues in the Marcellus Shale (Veil 2010). Gas production in the Marcellus Shale involves at least three states, many oil and gas operators, and multiple wastewater management options. Consequently, Veil (2010) provided extensive information on water. This current study is less complicated for several reasons: (1) gas production in the Fayetteville Shale is somewhat more mature and stable than production in the Marcellus Shale; (2) the Fayetteville Shale underlies a single state (Arkansas); (3) there are only a few gas producers that operate the large majority of the wells in the Fayetteville Shale; (4) much of the water management information relating to the Marcellus Shale also applies to the Fayetteville Shale, therefore, it can be referenced from Veil (2010) rather than being recreated here; and (5) the author has previously published a report on the Fayetteville Shale (Veil 2007) and has helped to develop an informational website on the Fayetteville Shale (Argonne and University of Arkansas 2008), both of these sources, which are relevant to the subject of this report, are cited as references.

  1. Management options for bipolar disorder in children and adolescents.

    PubMed

    Danielyan, Arman; Kowatch, Robert A

    2005-01-01

    During recent years there has been a dramatic increase in the use of psychotropic medication for the treatment of bipolar disorder (BPD) in children. There is an emerging set of data to support this use.Mood stabilizers, including lithium and valproic acid (valproate sodium), have generally formed the mainstay of treatment in children and adolescents with BPD. However, the atypical antipsychotics, such as risperidone, aripiprazole, and quetiapine may be more effective as first-line treatment options and in some ways easier to use than the traditional mood stabilizers. As in adults, mood stabilization is often difficult to achieve in pediatric patients with BPD, and combined treatment with mood stabilizers and atypical antipscyhotics is commonly used. Data from controlled trials of psychotropic medications in children and adolescents with BPD are very limited, and hence, in the majority of cases physicians base their treatment decisions on data from case reports, case series, or open trials. More controlled studies of both monotherapy and polypharmacotherapy for BPD in children and adolescents are needed. PMID:16220995

  2. Myelodysplastic Syndromes in the Elderly: Treatment Options and Personalized Management.

    PubMed

    Burgstaller, Sonja; Wiesinger, Petra; Stauder, Reinhard

    2015-11-01

    Myelodysplastic syndromes (MDS) are typical diseases of the elderly, with a median age of 68-75 years at initial diagnosis. Demographic changes producing an increased proportion of elderly in our societies mean the incidence of MDS will rise dramatically. Considering the increasing number of treatment options, ranging from best supportive care to hematopoietic stem cell transplantation (HSCT), decision making is rather complex in this cohort of patients. Moreover, aspects of the aging process also have to be considered in therapy planning. Treatment of elderly MDS patients is dependent on the patient's individual risk and prognosis. Comorbidities play an essential role as predictors of survival and therapy tolerance. Age-adjusted models and the use of geriatric assessment scores are described as a basis for individualized treatment algorithms. Specific treatment recommendations for the different groups of patients are given. Currently available therapeutic agents, including supportive care, erythropoiesis-stimulating agents (ESAs), immune-modulating agents, hypomethylating agents, and HSCT are described in detail and discussed with a special focus on elderly MDS patients. The inclusion of elderly patients in clinical trials is of utmost importance to obtain data on efficacy and safety in this particular group of patients. Endpoints relevant for the elderly should be integrated, including maintenance of quality of life and functional activities as well as evaluation of use of healthcare resources. PMID:26476843

  3. Management of patients with resistant hypertension: current treatment options

    PubMed Central

    Kumar, Nilay; Calhoun, David A; Dudenbostel, Tanja

    2013-01-01

    Resistant hypertension (RHTN) is an increasingly common clinical problem that is often heterogeneous in etiology, risk factors, and comorbidities. It is defined as uncontrolled blood pressure on optimal doses of three antihypertensive agents, ideally one being a diuretic. The definition also includes controlled hypertension with use of four or more antihypertensive agents. Recent observational studies have advanced the characterization of patients with RHTN. Patients with RHTN have higher rates of cardiovascular events and mortality compared with patients with more easily controlled hypertension. Secondary causes of hypertension, including obstructive sleep apnea, primary aldosteronism, renovascular disease, are common in patients with RHTN and often coexist in the same patient. In addition, RHTN is often complicated by metabolic abnormalities. Patients with RHTN require a thorough evaluation to confirm the diagnosis and optimize treatment, which typically includes a combination of lifestyle adjustments, and pharmacologic and interventional treatment. Combination therapy including a diuretic, a long-acting calcium channel blocker, an angiotensin-converting enzyme inhibitor, a beta blocker, and a mineralocorticoid receptor antagonist where warranted is the classic regimen for patients with treatment-resistant hypertension. Mineralocorticoid receptor antagonists like spironolactone or eplerenone have been shown to be efficacious in patients with RHTN, heart failure, chronic kidney disease, and primary aldosteronism. Novel interventional therapies, including baroreflex activation and renal denervation, have shown that both of these methods may be used to lower blood pressure safely, thereby providing exciting and promising new options to treat RHTN. PMID:24231917

  4. Management of keloids and hypertrophic scars: current and emerging options

    PubMed Central

    Gauglitz, Gerd G

    2013-01-01

    In the context of growing aesthetic awareness, a rising number of patients feel disappointed with their scars and are frequently seeking help for functional and aesthetic improvement. However, excessive scarring following surgery or trauma remains difficult to improve despite a plethora of advocated treatment strategies as frequently observed in daily clinical routine. It is thus still preferable to prevent scarring by minimizing risk factors as much as possible. Hence, it remains crucial for the physician to be aware of basic knowledge of healing mechanisms and skin anatomy, as well as an appreciation of suture material and wound closure techniques to minimize the risk of postoperative scarring. Next to existing, well known prophylactic and therapeutic strategies for the improvement of excessive scarring, this article discusses emerging techniques such as intralesional cryotherapy, intralesional 5-fluorouracil, interferon, and bleomycin. Some of them have been successfully tested in well-designed trials and already have extended or may extend the current spectrum of excessive scar treatment in the near future. Innovative options such as imiquimod 5% cream, photodynamic therapy, or botulinum toxin A may also be of certain importance; however, the data currently available is too contradictory for definite recommendations. PMID:23637546

  5. Management Options for a High Elevation Forest in the Alps

    NASA Astrophysics Data System (ADS)

    Jandl, R.; Jandl, N.; Schindlbacher, A.

    2013-12-01

    We explored different management strategies for a Cembran pine forest close to the timber line with respect to maintenance of the stand structure, the sequestration of carbon in the biomass and the soil, and the economical relevance of timber production. We used the forest growth simulation model Caldis for the implementation of three management intensities (zero managment, thinning every 30 years, thinning every 50 years) under two climate scenarios (IPCC A1B and B1). The soil carbon dynamics were analyzed with the simulation model Yasso07. The ecological evaluation of our simulation data showed that the extensive management with cutting interventions every 50 years allows the maintenance of the ecosystem carbon pool. Zero managment leads to the build-up of the carbon pool because the forest stand is rather unvulnerable to disturbances (bark beetle, storm). The more intensive mangement causes a decline in the ecosystem carbon pool. The economical evaluation showed the marginal relevance of the income generated by timber production. The main challenge is the compensation for the high harvesting costs (long-distance cable logging system). Even at extremely favorable market prices for timber from Cembran pine it is impossible to extract an appropriate amount of timber to justify the temporary instalment of the harvesting system and to maintain a stand density expected for a protection forest. We conclude that timber production is not a feasible object for mountain forests close to the timber line. Even in a warmer climate the productivity situation of forests close to the timberline will not change sufficiently. Therefore it will require public subsidies and personal efforts to maintain the silvicultural intensity at a level that is required for the sustainable maintenance of protection forests.

  6. Textile industry: Profile and DSM (demand-side management) options

    SciTech Connect

    Not Available

    1990-07-01

    The Textile Industry Guidebook provides electric utility planning, marketing, and customer service staff with a practical tool to better understand the textile industry and the challenges it faces; its manufacturing processes, technologies, and energy use; and its opportunities for demand-site management (DSM). The Guidebook concludes with guidance and summary data for developing and evaluating DSM plans to realize such opportunities. 5 refs., 37 figs., 52 tabs.

  7. Management and recovery options for Ural river beluga sturgeon.

    PubMed

    Doukakis, Phaedra; Babcock, Elizabeth A; Pikitch, Ellen K; Sharov, Alexei R; Baimukhanov, Mirgaly; Erbulekov, Sagiden; Bokova, Yelena; Nimatov, Akhat

    2010-06-01

    Management of declining fisheries of anadromous species sometimes relies heavily on supplementation of populations with captive breeding, despite evidence that captive breeding can have negative consequences and may not address the root cause of decline. The beluga sturgeon (Huso huso), a species threatened by the market for black caviar and reductions in habitat quality, is managed through harvest control and hatchery supplementation, with an emphasis on the latter. We used yield per recruit and elasticity analyses to evaluate the population status and current levels of fishing and to identify the life-history stages that are the best targets for conservation of beluga of the Ural River. Harvest rates in recent years were four to five times higher than rates that would sustain population abundance. Sustainable rates of fishing mortality are similar to those for other long-lived marine species such as sharks and mammals. Yield per recruit, which is maximized if fish are first harvested at age 31 years, would be greatly enhanced by raising minimum size limits or reducing illegal take of subadults. Improving the survival of subadult and adult females would increase population productivity by 10 times that achieved by improving fecundity and survival from egg to age 1 year (i.e., hatchery supplementation). These results suggest that reducing mortality of subadults and adult wild fish is a more effective conservation strategy than hatchery supplementation. Because genetics is not factored into hatchery management practices, supplementation may even reduce the viability of the beluga sturgeon. PMID:20184647

  8. Short Bowel Syndrome: A Review of Management Options

    PubMed Central

    Seetharam, Prasad; Rodrigues, Gabriel

    2011-01-01

    Extensive resection of the intestinal tract frequently results in inadequate digestion and/or absorption of nutrients, a condition known as short bowel syndrome (SBS). This challenging condition demands a dedicated multidisciplinary team effort to overcome the morbidity and mortality in these patients. With advances in critical care management, more and more patients survive the immediate morbidity of massive intestinal resection to present with SBS. Several therapies, including parenteral nutrition (PN), bowel rehabilitation and surgical procedures to reconstruct bowel have been used in these patients. Novel dietary approaches, pharmacotherapy and timely surgical interventions have all added to the improved outcome in these patients. However, these treatments only partially correct the underlying problem of reduced bowel function and have limited success resulting in 30% to 50% mortality rates. However, increasing experience and encouraging results of intestinal transplantation has added a new dimension to the management of SBS. Literature available on SBS is exhaustive but inconclusive. We conducted a review of scientific literature and electronic media with search terms 'short bowel syndrome, advances in SBS and SBS’ and attempted to give a comprehensive account on this topic with emphasis on the recent advances in its management. PMID:21727727

  9. Management of hepatitis delta: Need for novel therapeutic options

    PubMed Central

    Abbas, Zaigham; Abbas, Minaam

    2015-01-01

    Hepatitis D virus (HDV) is the smallest single stranded RNA virus infecting humans. The hepatitis B surface antigen envelope protein protects the HDV nucleocapsid antigen and provides a means for the virus to enter and exit the hepatocyte. Hepatitis B and D viruses exploit the human sodium taurocholate co-transporting polypeptide (NTCP), a receptor, for their entry into hepatocytes. Prenylation of the large delta antigen is a critical determinant of HDV particle assembly. Treatment with pegylated interferon results in sustained virological response six months post-treatment in one fourth of the patients. Nucleos(t)ide analogs (NAs) have been widely tested in hepatitis delta, but they appear to be ineffective. Combination treatment of NAs with interferon also proved to be disappointing so there is a need for novel therapeutic options. The receptor function of NTCP is blocked by Myrcludex B, a synthetic N-acylated preS1 lipopeptide that competes with infectious virions for receptor binding. There are already some approved drugs available, including irbesartan, ezetimibe, and ritonavir and cyclosporin A, with documented inhibitory effects on NTCP’s metabolic function. These drugs may have a role in HDV treatment. Interference with host-mediated post-translational changes of proteins that are crucial to the HDV life cycle, such as prenylation may become an important tool to control HDV infection and prevent replication. Lonafarnib, a prenylation inhibitor significantly reduces virus levels in hepatitis delta patients. Antisense oligodeoxynucleotides which are complementary to genomic HDV ribozyme self-cleavage site and stem I regions can inhibit genomic HDV ribozyme activity. PMID:26327754

  10. Options for the destruction of chemical weapons and management of the associated risks.

    PubMed

    Manley, Ron G

    2006-09-01

    The destruction of chemical weapons is a hazardous operation. The degree of hazard posed, however, is not uniform and is dependent on the specific chemical agent and the configuration of the weapon or bulk storage vessel in which it is contained. For example, a highly volatile nerve agent in an explosively configured munition, such as a rocket, poses a very different hazard from that of a bulk storage container of viscous mustard gas. Equally the handling of recovered, often highly corroded, World War (WW)I or WWII chemical munitions will pose a very different hazard from that associated with dealing with modern chemical weapons stored under the appropriate conditions. Over the years, a number of technologies have been developed for the destruction of chemical weapons. Each has its advantages and disadvantages. None of them provide a universal solution to the problem. When assessing options for the destruction of these weapons and the management of the associated risks, therefore, it is important to give due consideration and weight to these differences. To ensure that the destruction technology selected takes due account of them and that the resulting overall risk assessment accurately reflects the actual risks involved. PMID:17119231

  11. Alternative management and funding options for aeronautics programs, Task 1

    NASA Technical Reports Server (NTRS)

    1975-01-01

    Research and technology will be at lower program levels with basic military research for aviation decreasing as fewer aircraft programs are initiated and the present new aircraft programs move into the prototype and production status. The key question is can industry take on the management and financing role and meet the criteria and characteristics considered essential for a viable research and technology program. The criteria for evaluating alternative approaches include an examination of the nature of the product to be provided, responsiveness to changing needs, efficiency in terms of costs, ability to provide leadership, and to provide impartial and independent evaluation of approaches, and to provide technological inputs for regulating functions.

  12. Current and emerging treatment options in the management of lupus.

    PubMed

    Jordan, Natasha; D'Cruz, David

    2016-01-01

    Systemic lupus erythematosus (SLE) is a complex autoimmune disease with variable clinical manifestations. While the clearest guidelines for the treatment of SLE exist in the context of lupus nephritis, patients with other lupus manifestations such as neuropsychiatric, hematologic, musculoskeletal, and severe cutaneous lupus frequently require immunosuppression and/or biologic therapy. Conventional immunosuppressive agents such as mycophenolate mofetil, azathioprine, and cyclophosphamide are widely used in the management of SLE with current more rationalized treatment regimens optimizing the use of these agents while minimizing potential toxicity. The advent of biologic therapies has advanced the treatment of SLE particularly in patients with refractory disease. The CD20 monoclonal antibody rituximab and the anti-BLyS agent belimumab are now widely in use in clinical practice. Several other biologic agents are in ongoing clinical trials. While immunosuppressive and biologic agents are the foundation of inflammatory disease control in SLE, the importance of managing comorbidities such as cardiovascular risk factors, bone health, and minimizing susceptibility to infection should not be neglected. PMID:27529058

  13. Financial incentives: Possible options for sustainable rangeland management?

    PubMed

    Louhaichi, Mounir; Yigezu, Yigezu A; Werner, Jutta; Dashtseren, Lojoo; El-Shater, Tamer; Ahmed, Mohamed

    2016-09-15

    Large-scale mismanagement of natural resources emanating from lack of appropriate policies and regulatory framework is arguably one of the reasons that led to resource degradation and poor livelihoods in many countries in the Middle East and North Africa (MENA) region. Sustainable rangeland management practices (SRMPs) are considered to be a solution to feed shortages and rangeland degradation. However, the scope for SRMP adoption, has been a subject of debate. Using a case study from Syria and the application of the Minimum Data Analysis method (TOA-MD), this paper provides empirical evidence for ensuring wider adoption of SRMP. The paper argues that the introduction of financial incentives in the form of payments for agricultural-environmental services can increase the economic viability and enhance the adoption of SRMPs and is a better alternative to the unsustainable state subsidies for fodder purchases and barley cultivation on rangelands. Model results indicate that further investment in reasearch toward generating low cost technologies and tailored governance strategies including a financial incentive system would lead to better management of rangelands and improve livelihoods in the Syrian Badia. These findings are valuable for policy makers, donors as well as development and extension practitioners in the MENA region as they can better inform future courses of actions. PMID:27288553

  14. Current and emerging treatment options in the management of lupus

    PubMed Central

    Jordan, Natasha; D’Cruz, David

    2016-01-01

    Systemic lupus erythematosus (SLE) is a complex autoimmune disease with variable clinical manifestations. While the clearest guidelines for the treatment of SLE exist in the context of lupus nephritis, patients with other lupus manifestations such as neuropsychiatric, hematologic, musculoskeletal, and severe cutaneous lupus frequently require immunosuppression and/or biologic therapy. Conventional immunosuppressive agents such as mycophenolate mofetil, azathioprine, and cyclophosphamide are widely used in the management of SLE with current more rationalized treatment regimens optimizing the use of these agents while minimizing potential toxicity. The advent of biologic therapies has advanced the treatment of SLE particularly in patients with refractory disease. The CD20 monoclonal antibody rituximab and the anti-BLyS agent belimumab are now widely in use in clinical practice. Several other biologic agents are in ongoing clinical trials. While immunosuppressive and biologic agents are the foundation of inflammatory disease control in SLE, the importance of managing comorbidities such as cardiovascular risk factors, bone health, and minimizing susceptibility to infection should not be neglected. PMID:27529058

  15. Management of Haemophilia in Developing Countries: Challenges and Options.

    PubMed

    Ghosh, Kanjaksha; Ghosh, Kinjalka

    2016-09-01

    There are significant challenges in managing haemophilia patients in developing countries. These challenges are (i) Lack of proper health care infrastructure and human resources suitable for haemophilia care (ii) Competing health care priorities of the government. (iii) Lack of penetrance of medical insurance in the population. (iv) Lesser visibility of the haemophilia patients in health care system (v) Low awareness across the medical profession, population and the policy makers about the condition (vi) Non availability of factor concentrates (vii) Inadequate utilization of knowledge for reducing factor concentrate use. (viii) Inadequate pain relief (ix) Challenges due to inhibitor developing (x) Viral hepatitis & (xi) Lack of research publications relevant to the country are some of the challenges faced by PWH for their management in developing country. The solutions are not easy but development of a strong patient organization with linkages with World Federation of Haemophilia is an important initial step. Following that internal and international twinning, use of internal sources, strong advocacy programme targeting government, doctors, opinion makers will solve many of the challenges in the time to come. PMID:27429529

  16. New Pain Management Options for the Surgical Patient on Methadone and Buprenorphine.

    PubMed

    Sen, Sudipta; Arulkumar, Sailesh; Cornett, Elyse M; Gayle, Julie A; Flower, Ronda R; Fox, Charles J; Kaye, Alan D

    2016-03-01

    Perioperative management of patients receiving opioid addiction therapy presents a unique challenge for the anesthesiologist. The goal of pain management in this patient population is to effectively manage postoperative pain, to improve patient satisfaction and outcomes, and to reduce the cost of health care. Multimodal analgesics, including nonsteroid anti-inflammatory drugs, intravenous acetaminophen, gabapentanoid agents, and low-dose ketamine infusions, have been used to improve postoperative pain and to reduce postoperative opioid use. Patients on long-term opioid management therapy with methadone and buprenorphine require special considerations. Recommendations and options for treating postoperative pain in patients on methadone and buprenorphine are outlined below. Other postoperative pain management options include patient-controlled analgesia, intravenous, and transdermal, in addition to neuraxial and regional anesthesia techniques. Special patient populations include the parturient on long-term opioid therapy. Recommendations for use of opioids in these patients during labor and delivery and in the postpartum period are discussed. PMID:26879874

  17. Multilocular disseminated Tarlov cysts: Importance of imaging and management options

    PubMed Central

    Padma, Subramanyam; Palaniswamy, Shanmuga Sundaram

    2012-01-01

    With technological advancements and wider availability of multimodality imaging, incidental lesions are frequently identified in patients undergoing various imaging studies. We report here a case of multiloculated disseminated perineural or Tarlov cysts (TCs). The primary aim of this case study was to (1) provide a comprehensive review of the clinical, imaging, and histopathological features of TCs (2) to draw attention to the fact that multiple lumbosacral and dorsal TCs can produce nerve injuries and serious movement disturbances, and (3) to document the usefulness of the magnetic resonance imaging and bone scan in non-invasive diagnosis and guiding management in such cases. These cysts are clearly identified by magnetic resonance imaging (MRI) and computerized tomography imaging of the lumbosacral spine. However, there are no reports on the scintigraphic findings of multilocular disseminated TC in literature. TCs are typically benign, asymptomatic lesions that can simply be monitored. To date, no consensus exists about the best surgical strategy to use when indicated. PMID:23723584

  18. Multilocular disseminated Tarlov cysts: Importance of imaging and management options.

    PubMed

    Padma, Subramanyam; Palaniswamy, Shanmuga Sundaram

    2012-04-01

    With technological advancements and wider availability of multimodality imaging, incidental lesions are frequently identified in patients undergoing various imaging studies. We report here a case of multiloculated disseminated perineural or Tarlov cysts (TCs). The primary aim of this case study was to (1) provide a comprehensive review of the clinical, imaging, and histopathological features of TCs (2) to draw attention to the fact that multiple lumbosacral and dorsal TCs can produce nerve injuries and serious movement disturbances, and (3) to document the usefulness of the magnetic resonance imaging and bone scan in non-invasive diagnosis and guiding management in such cases. These cysts are clearly identified by magnetic resonance imaging (MRI) and computerized tomography imaging of the lumbosacral spine. However, there are no reports on the scintigraphic findings of multilocular disseminated TC in literature. TCs are typically benign, asymptomatic lesions that can simply be monitored. To date, no consensus exists about the best surgical strategy to use when indicated. PMID:23723584

  19. Global Change Drought in the Southwest: New Management Options

    NASA Astrophysics Data System (ADS)

    Udall, B. H.; Overpeck, J. T.

    2015-12-01

    Long held worries about future runoff declines in the Colorado River under climate change are proving to be more than just theory. Fifteen years into this century flows of the Colorado are already declining due mostly to unprecedented temperatures, and as warming proceeds, declines in river flow will grow larger. Temperature-driven droughts, some lasting decades and much more severe than the current 15-year drought, will also become more commonplace if climate change continues unabated. Current projections of future water availability almost universally understate the risk of large Colorado flow reductions under business-as-usual warming. Betting on highly uncertain projections of increased precipitation to overcome even part of the flow reductions due to virtually certain warming is a poor risk management strategy. Many of the existing water policy arrangements in the Colorado River Basin will fail in the 21st century unless innovative new solutions are developed under leadership from the federal government and its basin state partners.

  20. Management of stress in inflammatory bowel disease: a therapeutic option?

    PubMed

    Goodhand, James R; Wahed, Mahmood; Rampton, David S

    2009-12-01

    There is increasing evidence that psychological stress and associated mood disorders are linked with, and can adversely affect the course of, inflammatory bowel disease (IBD). Unfortunately, owing to methodological difficulties inherent in undertaking appropriately targeted and blinded trials, there are limited high-quality data regarding the effects on IBD of interventions aimed to ameliorate stress and mood disorders. Nevertheless, patients want psychological intervention as well as conventional medical strategies. Emerging trial evidence supports the suggestion that psychologically orientated therapy may ameliorate IBD-associated mood disorders, but there are no strong data as of yet to indicate that stress management has a beneficial effect on the activity or course of IBD. As yet, which, when and how interventions targeted at psychological stress and mood disturbances should be offered to individual patients with IBD is not clear. PMID:19929586

  1. Management options to limit nitrate leaching from grassland

    NASA Astrophysics Data System (ADS)

    Cuttle, S. P.; Scholefield, D.

    1995-12-01

    Nitrate leaching can be reduced by the adoption of less intensive grassland systems which, though requiring a greater land area to achieve the same agricultural output, result in less nitrate leaching per unit of production than do intensively managed grasslands. The economic penalties associated with reductions in output can be partly offset by greater reliance on symbiotic nitrogen fixation and the use of clover-based swards in place of synthetic N fertilisers. Alternatively, specific measures can be adopted to improve the efficiency of nitrogen use in intensively managed systems in order to maintain high outputs but with reduced losses. Controls should take account of other forms of loss and flows of nitrogen between grassland and other components of the whole-farm system and, in most instances, should result in an overall reduction in nitrogen inputs. Removing stock from the fields earlier in the grazing season will reduce the accumulation of high concentrations of potentially leachable nitrate in the soil of grazed pastures but will increase the quantity of manure produced by housed animals and the need to recycle this effectively. Supplementing grass diets with low-nitrogen forages such as maize silage will reduce the quantity of nitrogen excreted by livestock but may increase the potential for nitrate leaching elsewhere on the farm if changes to cropping patterns involve more frequent cultivation of grassland. Improved utilisation by the sward of nitrogen in animal excreta and manures and released by mineralisation of soil organic matter will permit equivalent reductions to be made in fertiliser inputs, provided that adequate information is available about the supply of nitrogen from these non-fertiliser sources.

  2. Management Options for Reducing the Release of Antibiotics and Antibiotic Resistance Genes to the Environment

    PubMed Central

    Pruden, Amy; Amézquita, Alejandro; Collignon, Peter; Brandt, Kristian K.; Graham, David W.; Lazorchak, James M.; Suzuki, Satoru; Silley, Peter; Snape, Jason R.; Topp, Edward; Zhang, Tong; Zhu, Yong-Guan

    2013-01-01

    Background: There is growing concern worldwide about the role of polluted soil and water environments in the development and dissemination of antibiotic resistance. Objective: Our aim in this study was to identify management options for reducing the spread of antibiotics and antibiotic-resistance determinants via environmental pathways, with the ultimate goal of extending the useful life span of antibiotics. We also examined incentives and disincentives for action. Methods: We focused on management options with respect to limiting agricultural sources; treatment of domestic, hospital, and industrial wastewater; and aquaculture. Discussion: We identified several options, such as nutrient management, runoff control, and infrastructure upgrades. Where appropriate, a cross-section of examples from various regions of the world is provided. The importance of monitoring and validating effectiveness of management strategies is also highlighted. Finally, we describe a case study in Sweden that illustrates the critical role of communication to engage stakeholders and promote action. Conclusions: Environmental releases of antibiotics and antibiotic-resistant bacteria can in many cases be reduced at little or no cost. Some management options are synergistic with existing policies and goals. The anticipated benefit is an extended useful life span for current and future antibiotics. Although risk reductions are often difficult to quantify, the severity of accelerating worldwide morbidity and mortality rates associated with antibiotic resistance strongly indicate the need for action. PMID:23735422

  3. An evaluation of thermal energy storage options for precooling gas turbine inlet air

    SciTech Connect

    Antoniak, Z.I.; Brown, D.R.; Drost, M.K.

    1992-12-01

    Several approaches have been used to reduce the temperature of gas turbine inlet air. One of the most successful uses off-peak electric power to drive vapor-compression-cycle ice makers. The ice is stored until the next time high ambient temperature is encountered, when the ice is used in a heat exchanger to cool the gas turbine inlet air. An alternative concept would use seasonal thermal energy storage to store winter chill for inlet air cooling. The objective of this study was to compare the performance and economics of seasonal thermal energy storage in aquifers with diurnal ice thermal energy storage for gas turbine inlet air cooling. The investigation consisted of developing computer codes to model the performance of a gas turbine, energy storage system, heat exchangers, and ancillary equipment. The performance models were combined with cost models to calculate unit capital costs and levelized energy costs for each concept. The levelized energy cost was calculated for three technologies in two locations (Minneapolis, Minnesota and Birmingham, Alabama). Precooling gas turbine inlet air with cold water supplied by an aquifer thermal energy storage system provided lower cost electricity than simply increasing the size of the turbine for meteorological and geological conditions existing in the Minneapolis vicinity. A 15 to 20% cost reduction resulted for both 0.05 and 0.2 annual operating factors. In contrast, ice storage precooling was found to be between 5 and 20% more expensive than larger gas turbines for the Minneapolis location. In Birmingham, aquifer thermal energy storage precooling was preferred at the higher capacity factor and ice storage precooling was the best option at the lower capacity factor. In both cases, the levelized cost was reduced by approximately 5% when compared to larger gas turbines.

  4. Real options analysis for land use management: Methods, application, and implications for policy.

    PubMed

    Regan, Courtney M; Bryan, Brett A; Connor, Jeffery D; Meyer, Wayne S; Ostendorf, Bertram; Zhu, Zili; Bao, Chenming

    2015-09-15

    Discounted cash flow analysis, including net present value is an established way to value land use and management investments which accounts for the time-value of money. However, it provides a static view and assumes passive commitment to an investment strategy when real world land use and management investment decisions are characterised by uncertainty, irreversibility, change, and adaptation. Real options analysis has been proposed as a better valuation method under uncertainty and where the opportunity exists to delay investment decisions, pending more information. We briefly review the use of discounted cash flow methods in land use and management and discuss their benefits and limitations. We then provide an overview of real options analysis, describe the main analytical methods, and summarize its application to land use investment decisions. Real options analysis is largely underutilized in evaluating land use decisions, despite uncertainty in policy and economic drivers, the irreversibility and sunk costs involved. New simulation methods offer the potential for overcoming current technical challenges to implementation as demonstrated with a real options simulation model used to evaluate an agricultural land use decision in South Australia. We conclude that considering option values in future policy design will provide a more realistic assessment of landholder investment decision making and provide insights for improved policy performance. PMID:26164637

  5. Hot asphalt burns: a review of injuries and management options.

    PubMed

    Bosse, George M; Wadia, Shernaz A; Padmanabhan, Pradeep

    2014-07-01

    Hot asphalt burns to human tissue can increase the likelihood of infection and potential conversion of partial thickness to full-thickness injuries. Successful intervention for hot asphalt burns requires immediate and effective cooling of the asphalt on the tissue followed by subsequent gradual removal of the cooled asphalt. A review of the literature reveals that multiple substances have been used to remove asphalt, including topical antibiotics, petroleum jelly, a commercial product known as De-Solv-It (ORANGE-SOL, Chandler, AZ), sunflower oil, baby oil, liquid paraffin, butter, mayonnaise, and moist-exposed burn ointment (MEBO). Although many of these products may be effective in the removal of asphalt, they may not be readily available in an emergency department setting. Topical antibiotics are readily available, are more commonly described in the medical literature, and would be expected to be effective in the removal of asphalt. We developed guidelines for on scene (first-aid) management and the initial care of such patients upon presentation to a health care facility. These guidelines emphasize the principles of early cooling, gradual removal of adherent asphalt using topical antibiotics, and avoidance of the use of topical agents, which are likely to result in tissue toxicity. PMID:24630605

  6. Analysis of options for coal combustion waste management in the Pacific Basin

    SciTech Connect

    Elcock, D.; Gasper, J.

    1993-10-01

    Many Pacific Basin countries rely on oil for electricity production. Alternative fuel sources such as coal, which is available in the Pacific Basin, can help mitigate adverse impacts of sudden price increases or supply disruptions. Coal combustion produces solid and potentially hazardous wastes of concern to environmental regulators and utility managers. This paper identifies issues associated with managing coal combustion wastes in the Pacific Basin, using the state of Hawaii as a case study. Hawaii is typical of many Pacific Basin locations in that it depends on oil, has limited sites, for waste management operations, and is subject to domestic and international waste management regulations. The paper discusses coal-fired utility wastes, environmental impacts of coal combustion waste disposal, and regulatory requirements that impact coal waste management. From this baseline, potential on- and off-island options for coal waste management are identified. Waste management costs are estimated and non-quantifiable issues are addressed for each option. Many options are applicable across the Pacific Rim and may serve as a basis for future fuel-use decisions.

  7. Greenhouse gas balances in low-productive drained boreal peatlands - is climate-friendly management possible?

    NASA Astrophysics Data System (ADS)

    Ojanen, Paavo; Minkkinen, Kari; Heikkinen, Tiina; Penttilä, Timo

    2016-04-01

    Five million hectares of peatland has been drained for forestry in Finland. About 20% of that, i.e. one million hectares, has been estimated to be so low-productive that the profitability of keeping them in forestry is questionable. At the same time, drainage has introduced changes in the ecosystem functions of these peatlands, including fluxes of greenhouse gases. Options to manage such peatlands include for example 1) no measures, i.e. leaving the drained peatlands as they are 2) increasing intensity by e.g. repetitive fertilisations and 3) restoration back to functional peatlands. Here we estimate the greenhouse gas impacts of these three management options. We collected GHG and organic carbon flux data from 50 low-productive peatlands under these management options over two years 2014-2015. Gas fluxes (CO2, CH4, N2O) were measured with closed chambers. Litter production rates of different plants above and below ground were estimated using litter traps (trees), biomass sampling (roots), through-grow nets (mosses), allometric biomass models (other vasculars) and published turnover rates (roots, other vasculars). Characteristics for estimating tree stand biomass increment were measured at each site from circular sample plots. In this presentation we will estimate the GHG impacts for the different management options, and aim to find the most climate-friendly options for the management of low-productive peatlands in the short and long term. This work was funded by Life+ LIFE12/ENV/FI/150.

  8. Life cycle analysis of management options for organic waste collected in an urban area.

    PubMed

    Di Maria, Francesco; Micale, Caterina

    2015-01-01

    Different options for managing the organic fraction (OF) of municipal solid waste generated in a given urban area were analyzed by life cycle assessment (LCA) for different source segregation (SS) intensities ranging from 0 to 52%. The best management option for processing the OF remaining in the residual organic fraction (ROF) for the different SS intensities was by incineration. Landfilling and mechanical biological treatment (MBT) of ROF gave higher impacts. Aerobic treatment alone or combined with anaerobic digestion (AD) for processing the source-segregated organic fraction (SSOF) led to relevant environmental impact reduction even if the difference between the two options was quite negligible. The weighted impact showed that scenarios using incineration always gave environmental gains, whereas there was a higher environmental burden with the scenarios using MBT. PMID:25060312

  9. 40 CFR 60.648 - Optional procedure for measuring hydrogen sulfide in acid gas-Tutwiler Procedure. 1

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... hydrogen sulfide in acid gas-Tutwiler Procedure. 1 60.648 Section 60.648 Protection of Environment..., 2011 § 60.648 Optional procedure for measuring hydrogen sulfide in acid gas—Tutwiler Procedure. 1 1 Gas... dilute solutions are used. In principle, this method consists of titrating hydrogen sulfide in a...

  10. 40 CFR 60.5408 - What is an optional procedure for measuring hydrogen sulfide in acid gas-Tutwiler Procedure?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... measuring hydrogen sulfide in acid gas-Tutwiler Procedure? 60.5408 Section 60.5408 Protection of Environment... § 60.5408 What is an optional procedure for measuring hydrogen sulfide in acid gas—Tutwiler Procedure... of titrating hydrogen sulfide in a gas sample directly with a standard solution of iodine....

  11. 40 CFR 60.648 - Optional procedure for measuring hydrogen sulfide in acid gas-Tutwiler Procedure. 1

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... hydrogen sulfide in acid gas-Tutwiler Procedure. 1 60.648 Section 60.648 Protection of Environment..., 2011 § 60.648 Optional procedure for measuring hydrogen sulfide in acid gas—Tutwiler Procedure. 1 1 Gas... dilute solutions are used. In principle, this method consists of titrating hydrogen sulfide in a...

  12. 40 CFR 60.5408 - What is an optional procedure for measuring hydrogen sulfide in acid gas-Tutwiler Procedure?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... measuring hydrogen sulfide in acid gas-Tutwiler Procedure? 60.5408 Section 60.5408 Protection of Environment... § 60.5408 What is an optional procedure for measuring hydrogen sulfide in acid gas—Tutwiler Procedure... of titrating hydrogen sulfide in a gas sample directly with a standard solution of iodine....

  13. Is orthodontics an option in the management of bimaxillary protrusion?

    PubMed

    Dawjee, S M; Becker, P J; Hlongwa, P

    2010-10-01

    Successful orthodontic treatment is based on a clear perception by the clinician of a patient's facial preference and treatment needs. Bimaxillary protrusion is a normal facial trait seen in the Black population and the most acceptable bimaxillary facial profile in a sample of Black subjects was determined by Beukes et al in 2007. Variations from this ideal profile may require extractions as part of orthodontic treatment in order to attain the ideal. The objective of this study was to determine whether Black subjects with bimaxillary protrusion would want to change their facial profile to the ideal and at what financial cost. A sample of 586 school learners and 321 university students were presented with four silhouetted profiles of varying degrees of bimaxillary protrusion. One of the silhouette profiles represented the ideal and treatment procedures required to achieve this ideal were explained to the sample. They were then requested to answer a questionnaire that would assist in identifying their perception of their own profile and their desire to change their appearance. The ideal silhouette was confirmed to be the most attractive (91.51%) and the sample felt that any severe deviations from this ideal profile should be treated. The financial cost of treatment was found to be a concern, as more subjects (62.84%) would undergo the required treatment if it were free. Many subjects (43.55%) would be prepared to pay for the necessary treatment to achieve the ideal profile. Females were found to be more definite in their decision making, reflecting a greater awareness about their aesthetic appearance than their male counterparts. Findings from this study can serve as an essential tool to assist both orthodontists and maxillofacial surgeons in the treatment planning and management of Black patients with bimaxillary protrusion. PMID:21180286

  14. Parkinson's Disease and Its Management: Part 3: Nondopaminergic and Nonpharmacological Treatment Options.

    PubMed

    DeMaagd, George; Philip, Ashok

    2015-10-01

    This installment of a five-part series reviews the role of nondopaminergic pharmacotherapies and adjunctive options-such as monoamine oxidase type B inhibitors, catechol-O-methyltransferase inhibitors, and anticholinergic agents-in managing Parkinson's disease. Nonpharmacological treatments are also explored. PMID:26535023

  15. A Many-Objective Analysis of Supply and Demand Management Options for the Thames Basin

    NASA Astrophysics Data System (ADS)

    Huskova, I.; Matrosov, E.; Kasprzyk, J. R.; Harou, J. J.; Reed, P. M.

    2012-12-01

    In this study we link water basin simulation and many-objective evolutionary optimization to evaluate tradeoffs for the water stressed Thames water supply system in South East England which includes the city of London. We consider both infrastructure additions and demand management options to satisfy the future supply/demand balance, in order to develop management alternatives that can meet a range of fiscal and performance constraints under future supply and demand trajectories. The suite of new infrastructure options includes a new reservoir, water transfers, conjunctive use of groundwater, wastewater reuse and brackish groundwater desalination. Additionally, demand management options include leakage reduction, compulsory metering and the introduction of seasonal tariffs. Infrastructure options are evaluated using quantitative performance measures that minimize costs and energy use while maximizing engineering, social and environmental performance, subject to supply reliability constraints set by the local water utility and the Environment Agency regulator. Pareto approximate trade-off curves show the tradeoffs between engineering, cost, social and environmental performance measures. We use interactive visual analytics to show the performance of solutions across a broad range of performance measures and interrogate the impact of the infrastructure portfolios on the performance measures. Using an optimization—simulation framework enables the consideration of non-linear and rule-based phenomena, which are frequently useful or necessary to accurately describe how real water systems are managed. Results suggest that a diverse portfolio of supply-side and demand side options can aid water management in the UK. The Thames basin is modeled using a generalized computationally efficient open-source water resource simulator, Interactive River-Aquifer Simulation-2010 (IRAS-2010). The IRAS-2010 Thames system model is linked via a C++ wrapper to the Epsilon Dominance

  16. Disposal/recovery options for brine waters from oil and gas production in New York State. Final report

    SciTech Connect

    Matsumoto, M.R.; Atkinson, J.F.; Bunn, M.D.; Hodge, D.S.

    1996-03-01

    Produced water from oil and gas operations, or brine as it is typically referred, may be characterized as being highly saline, with total dissolved solids greater than 100 g/L. If these bribes are disposed improperly there may be severe adverse environmental effects. Thus, it is important that brine be disposed using environmentally sound methods. Unfortunately, costs for the disposal of brine water are a significant burden to oil and gas producers in New York State. These costs and the relatively low market price of oil and natural gas have contributed to the decline in gas and oil production in New York State during the past 10 years. The objectives of this study were to evaluate new and existing options for brine disposal in New York State, examine the technical and economic merits of these options, and assess environmental impacts associated with each option. Two new disposal options investigated for New York State oil and gas producers included construction of a regional brine treatment facility to treat brine prior to discharge into a receiving water and a salt production facility that utilizes produced water as a feed stock. Both options are technically feasible; however, their economic viability depends on facility size and volume of brine treated.

  17. GRAFEC: A New Spanish Program to Investigate Waste Management Options for Radioactive Graphite - 12399

    SciTech Connect

    Marquez, Eva; Pina, Gabriel; Rodriguez, Marina; Fachinger, Johannes; Grosse, Karl-Heinz; Leganes Nieto, Jose Luis; Quiros Gracian, Maria

    2012-07-01

    graphite in a long term stable glass matrix. The principal applicability has been already proved by FNAG. Crushed graphite mixed with a suitable glass powder has been pressed at elevated temperature under vacuum. The vacuum is required to avoid gas enclosures in the obtained product. The obtained products, named IGM for 'Impermeable Graphite Matrix', have densities above 99% of theoretical density. The amount of glass has been chosen with respect to the pore volume of the former graphite parts. The method allows the production of encapsulated graphite without increasing the disposal volume. This paper will give a short overview of characterisation results of different irradiated graphite materials obtained at CIEMAT and in the Carbowaste project as well as the proposed methods and the actual status of the program including first results about leaching of non-radioactive IGM samples and hopefully first tendencies concerning the C-14 separation from graphite of Vandellos I by thermal treatment. Both processes, the thermal treatment as well as the IGM, have the potential to solve problems related to the management of irradiated graphite in Spain. However the methods have only been tested with different types of i-graphite and virgin graphite, respectively. Only investigations with real i-graphite from Spain will reveal whether the described methods are applicable to graphite from Vandellos I. However all partners are convinced that one of these new methods or a combination of them will lead to a feasible option to manage i-graphite in Spain on an industrial scale. (authors)

  18. Technological options for management of hazardous wastes from US Department of Energy facilities

    SciTech Connect

    Chiu, S.; Newsom, D.; Barisas, S.; Humphrey, J.; Fradkin, L.; Surles, T.

    1982-08-01

    This report provides comprehensive information on the technological options for management of hazardous wastes generated at facilities owned or operated by the US Department of Energy (DOE). These facilities annually generate a large quantity of wastes that could be deemed hazardous under the Resource Conservation and Recovery Act (RCRA). Included in these wastes are liquids or solids containing polychlorinated biphenyls, pesticides, heavy metals, waste oils, spent solvents, acids, bases, carcinogens, and numerous other pollutants. Some of these wastes consist of nonnuclear hazardous chemicals; others are mixed wastes containing radioactive materials and hazardous chemicals. Nearly 20 unit processes and disposal methods are presented in this report. They were selected on the basis of their proven utility in waste management and potential applicability at DOE sites. These technological options fall into five categories: physical processes, chemical processes, waste exchange, fixation, and ultimate disposal. The options can be employed for either resource recovery, waste detoxification, volume reduction, or perpetual storage. Detailed descriptions of each technological option are presented, including information on process performance, cost, energy and environmental considerations, waste management of applications, and potential applications at DOE sites. 131 references, 25 figures, 23 tables.

  19. The Template for Assessing Climate Change Impacts and Management Options (TACCIMO): Science at Your Fingertips

    NASA Astrophysics Data System (ADS)

    Jennings, L. N.; Treasure, E.; Moore Myers, J.; McNulty, S.

    2012-12-01

    There is an ever-increasing volume of useful scientific knowledge about climate change effects and management options for natural ecosystems. Agencies such as the USDA Forest Service have been charged with the need to evaluate this body of knowledge and if necessary adapt to the impacts of climate change in their forest planning and management. However, the combined volume of existing information and rate of development of new information, lack of climate change specialists, and limited technology transfer mechanisms make efficient access and use difficult. The Template for Assessing Climate Change Impacts and Management Options (TACCIMO) addresses this difficulty through its publically accessible web-based tool that puts current and concise climate change science at the fingertips of forest planners and managers. A collaborative product of the USDA Forest Service Research Stations and the National Forest System, TACCIMO integrates peer-reviewed research with management and planning options through search and reporting tools that connect land managers with information they can trust. TACCIMO highlights elements from the wealth of climate change science with attention to what natural resource planners and managers need through a searchable repository of over 4,000 effects of climate change and close to 1,000 adaptive management options, all excerpted from a growing body of peer-reviewed scientific literature. A geospatial mapping application provides downscaled climate data for the nation and other spatially explicit models relevant to evaluating climate change impacts on forests. Report generators assist users in capturing outputs specific to a given location and resource area in a consistent and organized manner. For USDA Forest Service users, science findings can be readily linked with management conditions and capabilities from national forest management plans. The development of TACCIMO was guided by interactions with natural resource professionals, resulting

  20. Options for managing hypoxic blackwater events in river systems: a review.

    PubMed

    Kerr, Janice L; Baldwin, Darren S; Whitworth, Kerry L

    2013-01-15

    Blackwater events are characterised by a high concentration of dissolved organic carbon in the water column. They occur naturally in lowland rivers with forested floodplains and bring a variety of benefits to both aquatic and floodplain biota. However, particularly when accompanied by high temperatures, respiration of the organic carbon may cause blackwater to become hypoxic. This may lead to a range of lethal and sub-lethal effects on the aquatic biota. We review the current scientific knowledge concerning the management of blackwater and hypoxia, and examine how this knowledge may be applied to the management of hypoxic blackwater events in lowland river systems. A range of management options, which aim to either prevent the development of hypoxic blackwater or to reintroduce oxygen into deoxygenated waters, are reported. Mitigation options that may be applicable to lowland river systems include manipulating the season and magnitude of floods in regulated rivers, increasing roughness in flow paths, establishing oxygenated refugia for aquatic biota and introducing hydraulic structures that promote turbulence and re-aeration. With climatic changes trending towards a scenario where extreme events leading to the development of hypoxic blackwater are more probable, it is now vital to validate and optimise management options on local and regional scales and work towards closing knowledge gaps. With judicious management of regulated rivers, it is possible to minimise the impacts of hypoxic flows while preserving the benefits brought to floodplain and river ecosystems by seasonal flooding and carbon exchange. PMID:23137913

  1. Evaluating ecosystem-based management options: Effects of trawling in Torres Strait, Australia

    NASA Astrophysics Data System (ADS)

    Ellis, Nick; Pantus, Francis; Welna, Andrzej; Butler, Alan

    2008-09-01

    A suite of management options for a prawn trawl fishery in Torres Strait, Australia was assessed for impacts on the benthic fauna using a dynamic management strategy evaluation approach. The specification of the management options was gained through consultation with stakeholders. Data for the model was drawn from several sources: the fleet data from fishery logbooks and satellite vessel monitoring systems, benthic depletion rates from trawl-down experiments, benthic recovery rates from post-experiment recovery monitoring studies, and benthic distribution from large-scale benthic surveys. Although there were large uncertainties in the resulting indicators, robust measures relevant to management were obtained by taking ratios relative to the status quo. The management control with the biggest effect was total effort; reducing trawl effort always led to increases in benthic faunal density of up to 10%. Spatial closures had a smaller benefit of up to 2%. The effect of closing a set of buffer zones around reefs to trawling was indistinguishable from the status quo option. Closing a larger area, however, was largely beneficial especially for sea cucumbers. When the spatial distributions of fauna prior to fishing were accounted for, fauna with distributions positively correlated with effort improved relative to those negatively correlated. The reduction in prawn catch under effort reduction scenarios could be ameliorated by introducing temporal closures over the full-moon period.

  2. Proceedings of the 1999 Oil and Gas Conference: Technology Options for Producer Survival

    SciTech Connect

    None available

    2000-04-12

    The 1999 Oil & Gas Conference was cosponsored by the U.S. Department of Energy (DOE), Office of Fossil Energy, Federal Energy Technology Center (FETC) and National Petroleum Technology Office (NPTO) on June 28 to 30 in Dallas, Texas. The Oil & Gas Conference theme, Technology Options for Producer Survival, reflects the need for development and implementation of new technologies to ensure an affordable, reliable energy future. The conference was attended by nearly 250 representatives from industry, academia, national laboratories, DOE, and other Government agencies. Three preconference workshops (Downhole Separation Technologies: Is it Applicable for Your Operations, Exploring and developing Naturally Fractured Low-Permeability Gas Reservoirs from the Rocky Mountains to the Austin Chalk, and Software Program Applications) were held. The conference agenda included an opening plenary session, three platform sessions (Sessions 2 and 3 were split into 2 concurrent topics), and a poster presentation reception. The platform session topics were Converting Your Resources Into Reserves (Sessions 1 and 2A), Clarifying Your Subsurface Vision (Session 2B), and High Performance, Cost Effective Drilling, Completion, Stimulation Technologies (Session 3B). In total, there were 5 opening speakers, 30 presenters, and 16 poster presentations.

  3. Greenhouse gas mitigation options in the forest sector of Russia: National and project level assessments

    SciTech Connect

    Vinson, T.S.; Kolchugina, T.P.; Andrasko, K.A.

    1996-09-01

    Greenhouse gas (GHG) mitigation options in the Russian forest sector include: afforestation and reforestation of unforested/degraded land area; enhanced forest productivity; incorporation of nondestructive methods of wood harvesting in the forest industry; establishment of land protective forest stands; increase in stand age of final harvest in the European part of Russia; increased fire control; increased disease and pest control; and preservation of old growth forests in the Russian Far-East, which are presently threatened. Considering the implementation of all of the options presented, the GHG mitigation potential within the forest and agroforestry sectors of Russia is approximately 0.6-0.7 Pg C/yr or one half of the industrial carbon emissions of the United States. The difference between the GHG mitigation potential and the actual level of GHGs mitigated in the Russian forest sector will depend to a great degree on external financing that may be available. One possibility for external financing is through joint implementation (JI). However, under the JI process, each project will be evaluated by considering a number of criteria including also the difference between the carbon emissions or sequestration for the baseline (or reference) and the project case, the permanence of the project, and leakage. Consequently, a project level assessment must appreciate the near-term constraints that will face practitioners who attempt to realize the GHG mitigation potential in the forest and agroforestry sectors of their countries. 25 refs.

  4. Energy-saving options for the mitigation of greenhouse gas emissions from the Mongolian energy sector

    SciTech Connect

    Dorjpurev, J.; Purevjal, O.; Erdenechimeg, Ch.

    1996-12-31

    The Energy sector is the largest contributor to GHG emission in Mongolia. The Energy sector emits 54 percent of CO2 and 4 percent of methane. All emissions of other greenhouse gases are accounted from energy related activities. The activities in this sector include coal production, fuel combustion, and biomass combustion at the thermal power stations and in private houses (stoves) for heating purposes. This paper presents some important Demand-side options considered for mitigation of CO2 emissions from energy sector such as Energy Conservation in Industrial Sector and in Buildings. Changes in energy policies and programmes in the Mongolian situation that promote more efficient and sustainable practices are presented in the paper. These energy saving measures will not only help reduce greenhouse gas emissions, but will also promote economic development and alleviate other environmental problems.

  5. Internalizing production externalities: A structural estimation of real options in the upstream oil and gas industry

    NASA Astrophysics Data System (ADS)

    Muehlenbachs, Lucija

    implies that typically wells are left inactive not because of the option to reactivate, but rather because the cost of environmental cleanup is too high. Should there be externalities from idling the wells (such as continued contamination of groundwater) that are not accounted for in the decision, then this behavior may not be socially optimal. The model predicts that a Pigouvian tax on inactive wells would have the added benefit of inciting the reactivation of oil and gas wells, however in the case of oil, a tax would incite more wells to be decommissioned than reactivated.

  6. Taking Action Against Ocean Acidification: A Review of Management and Policy Options

    NASA Astrophysics Data System (ADS)

    Billé, Raphaël; Kelly, Ryan; Biastoch, Arne; Harrould-Kolieb, Ellycia; Herr, Dorothée; Joos, Fortunat; Kroeker, Kristy; Laffoley, Dan; Oschlies, Andreas; Gattuso, Jean-Pierre

    2013-10-01

    Ocean acidification has emerged over the last two decades as one of the largest threats to marine organisms and ecosystems. However, most research efforts on ocean acidification have so far neglected management and related policy issues to focus instead on understanding its ecological and biogeochemical implications. This shortfall is addressed here with a systematic, international and critical review of management and policy options. In particular, we investigate the assumption that fighting acidification is mainly, but not only, about reducing CO2 emissions, and explore the leeway that this emerging problem may open in old environmental issues. We review nine types of management responses, initially grouped under four categories: preventing ocean acidification; strengthening ecosystem resilience; adapting human activities; and repairing damages. Connecting and comparing options leads to classifying them, in a qualitative way, according to their potential and feasibility. While reducing CO2 emissions is confirmed as the key action that must be taken against acidification, some of the other options appear to have the potential to buy time, e.g. by relieving the pressure of other stressors, and help marine life face unavoidable acidification. Although the existing legal basis to take action shows few gaps, policy challenges are significant: tackling them will mean succeeding in various areas of environmental management where we failed to a large extent so far.

  7. Waste heat recovery options in a large gas-turbine combined power plant

    NASA Astrophysics Data System (ADS)

    Upathumchard, Ularee

    This study focuses on power plant heat loss and how to utilize the waste heat in energy recovery systems in order to increase the overall power plant efficiency. The case study of this research is a 700-MW natural gas combined cycle power plant, located in a suburban area of Thailand. An analysis of the heat loss of the combustion process, power generation process, lubrication system, and cooling system has been conducted to evaluate waste heat recovery options. The design of the waste heat recovery options depends to the amount of heat loss from each system and its temperature. Feasible waste heat sources are combustion turbine (CT) room ventilation air and lubrication oil return from the power plant. The following options are being considered in this research: absorption chillers for cooling with working fluids Ammonia-Water and Water-Lithium Bromide (in comparison) and Organic Rankine Cycle (ORC) with working fluids R134a and R245fa. The absorption cycles are modeled in three different stages; single-effect, double-effect and half-effect. ORC models used are simple ORC as a baseline, ORC with internal regenerator, ORC two-phase flash expansion ORC and ORC with multiple heat sources. Thermodynamic models are generated and each system is simulated using Engineering Equation Solver (EES) to define the most suitable waste heat recovery options for the power plant. The result will be synthesized and evaluated with respect to exergy utilization efficiency referred as the Second Law effectiveness and net output capacity. Results of the models give recommendation to install a baseline ORC of R134a and a double-effect water-lithium bromide absorption chiller, driven by ventilation air from combustion turbine compartment. The two technologies yield reasonable economic payback periods of 4.6 years and 0.7 years, respectively. The fact that this selected power plant is in its early stage of operation allows both models to economically and effectively perform waste heat

  8. The conversion of grassland to acacia forest as an effective option for net reduction in greenhouse gas emissions.

    PubMed

    de Godoi, Stefânia Guedes; Neufeld, Ângela Denise Hubert; Ibarr, Mariana Alves; Ferreto, Décio Oscar Cardoso; Bayer, Cimélio; Lorentz, Leandro Homrich; Vieira, Frederico Costa Beber

    2016-03-15

    This study aimed to evaluate the effect of forestation with leguminous Acacia mearnsii De Wild in native grasslands on the soil greenhouse (GHG) fluxes and their main driving factors. The experiment was conducted in the Brazilian Pampa over the period of one year in a six-year-old Acacia plantation, evaluating four treatments: Acacia (AM), Acacia with litter periodically removed (A-l), Acacia after harvest (AH) and native grassland (NG) (reference treatment). Air samples were obtained by the static chamber method, and gas concentrations were evaluated by gas chromatography. Soil and climate factors were monitored. The accumulated fluxes of methane (CH4) and nitrous oxide (N2O) were statistically similar between the soils in the AM and NG treatments, which tended to oxidize CH4 (-1445 and -1752 g C-CH4 ha(-1) yr(-1), respectively) and had low emission of N2O (242 and 316 g N-N2O ha(-1) yr(-1)), most likely influenced by the low water-filled pore space and the low content of mineral N in the soil. However, the soil in the AH treatment presented higher emissions of both gases, totaling 1889 g C-CH4 ha(-1) yr(-1) and 1250 g N-N2O ha(-1) yr(-1). Afforestation neither significantly affected the total organic C stocks nor their lability, keeping the C management index for the forested area similar to that in the NG treatment. The conversion from grassland to Acacia forest represents an effective option for mitigating the net reduction in greenhouse gas emissions, which is basically determined by C accumulation in biomass and wood products. PMID:26731308

  9. Herbal Medicine Offered as an Initiative Therapeutic Option for the Management of Hepatocellular Carcinoma.

    PubMed

    Chen, Shao-Ru; Qiu, Hong-Cong; Hu, Yang; Wang, Ying; Wang, Yi-Tao

    2016-06-01

    Hepatocellular carcinoma (HCC) is a common malignant cancer and is the third leading cause of death worldwide. Effective treatment of this disease is limited by the complicated molecular mechanism underlying HCC pathogenesis. Thus, therapeutic options for HCC management are urgently needed. Targeting the Wnt/β-catenin, Hedgehog, Notch, and Hippo-YAP signaling pathways in cancer stem cell development has been extensively investigated as an alternative treatment. Herbal medicine has emerged as an initiative therapeutic option for HCC management because of its multi-level, multi-target, and coordinated intervention effects. In this article, we summarized the recent progress and clinical benefits of targeting the above mentioned signaling pathways and using natural products such as herbal medicine formulas to treat HCC. Proving the clinical success of herbal medicine is expected to deepen the knowledge on herbal medicine efficiency and hasten the adoption of new therapies. Copyright © 2016 John Wiley & Sons, Ltd. PMID:26879574

  10. Greenhouse gas mitigation options in the forestry sector of The Gambia: Analysis based on COMAP model

    SciTech Connect

    Jallow, B.P.

    1996-12-31

    Results of the 1993 Greenhouse Gas Emissions Inventory of The Gambia showed net CO{sub 2} emissions of over (1.66 x 10{sup 6} tons) and 1% was due to uptake by plantations (0.01 x 10{sup 6} tons). This is a clear indication that there is need to identify changes in the land-use policy, law and tenure that discourages forest clearing at the same time significantly influencing the sustainable distribution of land among forestry, rangeland and livestock, and agriculture. About 11% of the total area of The Gambia is either fallow or barren flats that once supported vegetation and hence is still capable of supporting vegetation. The US Country Study Programme has provided the Government of The Gambia through the National Climate Committee funds to conduct Assessment of Mitigation Options to Reduce Greenhouse Gas Emissions. The Forestry Sector is one area for which assessment is being conducted. The assessment is expected to end in September 1996. The Comprehensive Mitigation Analysis Process (COMAP) is one of the Models supplied to the National Climate Committee by the Lawrence Berkeley Laboratory, on behalf of the US Country Study Programme, and is being used to conduct the analysis in The Gambia.

  11. Intramedullary Spinal Cord Tumors: Part II—Management Options and Outcomes

    PubMed Central

    Samartzis, Dino; Gillis, Christopher C.; Shih, Patrick; O'Toole, John E.; Fessler, Richard G.

    2015-01-01

    Study Design Broad narrative review. Objectives Intramedullary spinal cord tumors (IMSCT) are uncommon lesions that can affect any age group or sex. However, numerous IMSCT exist and the clinical course of each tumor varies. The following article addresses the various management options and outcomes in patients with IMSCT. Methods An extensive review of the peer-reviewed literature was performed, addressing management options and clinical outcomes of patients with IMSCT. Results Early diagnosis and intervention are essential to obtain optimal functional outcome. Each IMSCT have specific imaging characteristics, which help in the clinical decision-making and prognostication. A comprehension of the tumor pathology and the clinical course associated with each tumor can allow for the proper surgical and nonsurgical management of these tumors, and reduce any associated morbidity and mortality. Recent advances in the operative management of such lesions have increased the success rate of tumor removal while minimizing iatrogenic-related trauma to the patient and, in tandem, improving patient outcomes. Conclusions Awareness and understanding of IMSCT is imperative to design proper management and obtain optimal patient outcomes. Meticulous operative technique and the use of surgical adjuncts are essential to accomplish proper tumor removal, diminish the risk of recurrence, and preserve neurologic function. Operative management of IMSCT should be individualized and based on tumor type, location, and dimensional extensions. To assist with preoperative and intraoperative decision-making, a general algorithm is provided. PMID:26933620

  12. Life-cycle assessment of selected management options for air pollution control residues from waste incineration.

    PubMed

    Fruergaard, Thilde; Hyks, Jiri; Astrup, Thomas

    2010-09-15

    Based on available technology and emission data seven selected management options for air-pollution-control (APC) residues from waste incineration were evaluated by life-cycle assessment (LCA) using the EASEWASTE model. Scenarios were evaluated with respect to both non-toxicity impact categories (e.g. global warming) and toxicity related impact categories (e.g. ecotoxicity and human toxicity). The assessment addressed treatment and final placement of 1 tonne of APC residue in seven scenarios: 1) direct landfilling without treatment (baseline), 2) backfilling in salt mines, 3) neutralization of waste acid, 4) filler material in asphalt, 5) Ferrox stabilization, 6) vitrification, and 7) melting with automobile shredder residues (ASR). The management scenarios were selected as examples of the wide range of different technologies available worldwide while at the same time using realistic technology data. Results from the LCA were discussed with respect to importance of: energy consumption/substitution, material substitution, leaching, air emissions, time horizon aspects for the assessment, and transportation distances. The LCA modeling showed that thermal processes were associated with the highest loads in the non-toxicity categories (energy consumption), while differences between the remaining alternatives were small and generally considered insignificant. In the toxicity categories, all treatment/utilization options were significantly better than direct landfilling without treatment (lower leaching), although the thermal processes had somewhat higher impacts than the others options (air emissions). Transportation distances did not affect the overall ranking of the management alternatives. PMID:20599249

  13. 43 CFR 3100.3-2 - Effect of option on acreage.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false Effect of option on acreage. 3100.3-2... MANAGEMENT, DEPARTMENT OF THE INTERIOR MINERALS MANAGEMENT (3000) OIL AND GAS LEASING Onshore Oil and Gas Leasing: General § 3100.3-2 Effect of option on acreage. The acreage to which the option is...

  14. Papillon–Lefèvre syndrome: clinical presentation and management options

    PubMed Central

    Sreeramulu, Basapogu; Shyam, Naragani DVN; Ajay, Pilla; Suman, Pathipaka

    2015-01-01

    Papillon–Lefèvre syndrome (PLS) is a rare autosomal recessive disorder, characterized by diffuse palmoplantar keratoderma and precocious aggressive periodontitis, leading to premature loss of deciduous and permanent dentition at a very young age. Various etiopathogenic factors are associated with the syndrome, like immunologic alterations, genetic mutations, and the role of bacteria. Dentists play a significant role in the diagnosis and management of PLS as there are characteristic manifestations like periodontal destruction at an early age and an early eruption of permanent teeth. Here, we are presenting an elaborate review of PLS, its etiopathogenesis, clinical presentation, and management options. PMID:26203280

  15. Papillon-Lefèvre syndrome: clinical presentation and management options.

    PubMed

    Sreeramulu, Basapogu; Shyam, Naragani Dvn; Ajay, Pilla; Suman, Pathipaka

    2015-01-01

    Papillon-Lefèvre syndrome (PLS) is a rare autosomal recessive disorder, characterized by diffuse palmoplantar keratoderma and precocious aggressive periodontitis, leading to premature loss of deciduous and permanent dentition at a very young age. Various etiopathogenic factors are associated with the syndrome, like immunologic alterations, genetic mutations, and the role of bacteria. Dentists play a significant role in the diagnosis and management of PLS as there are characteristic manifestations like periodontal destruction at an early age and an early eruption of permanent teeth. Here, we are presenting an elaborate review of PLS, its etiopathogenesis, clinical presentation, and management options. PMID:26203280

  16. Elective preterm delivery as a management option in cryptogenic organizing pneumonia

    PubMed Central

    Holder, Kelly L; Scardo, James A; Laye, M Ryan

    2011-01-01

    Bronchiolitis obliterans organizing pneumonia, now termed as cryptogenic organizing pneumonia (COP), is a fibrotic lung disease of the small airways with the potential to progress to end-stage lung disease. COP in pregnancy carries a high risk of maternal and neonatal complications and only two prior cases have been reported. This is the first case of pre-existing COP in pregnancy. We report a 16-year-old primigravid with COP who elected inpatient management and preterm delivery as a successful management option.

  17. The RealGas and RealGasH2O options of the TOUGH+ code for the simulation of coupled fluid and heat flow in tight/shale gas systems

    EPA Science Inventory

    We developed two new EOS additions to the TOUGH+ family of codes, the RealGasH2O and RealGas. The RealGasH2O EOS option describes the non-isothermal two-phase flow of water and a real gas mixture in gas reservoirs, with a particular focus in ultra-tight (such as tight-sand and sh...

  18. Waste Management Options for Long-Duration Space Missions: When to Reject, Reuse, or Recycle

    NASA Technical Reports Server (NTRS)

    Linne, Diane L.; Palaszewski, Bryan A.; Gokoglu, Suleyman; Gallo, Christopher A.; Balasubramaniam, Ramaswamy; Hegde, Uday G.

    2014-01-01

    The amount of waste generated on long-duration space missions away from Earth orbit creates the daunting challenge of how to manage the waste through reuse, rejection, or recycle. The option to merely dispose of the solid waste through an airlock to space was studied for both Earth-moon libration point missions and crewed Mars missions. Although the unique dynamic characteristics of an orbit around L2 might allow some discarded waste to intersect the lunar surface before re-impacting the spacecraft, the large amount of waste needed to be managed and potential hazards associated with volatiles recondensing on the spacecraft surfaces make this option problematic. A second option evaluated is to process the waste into useful gases to be either vented to space or used in various propulsion systems. These propellants could then be used to provide the yearly station-keeping needs at an L2 orbit, or if processed into oxygen and methane propellants, could be used to augment science exploration by enabling lunar mini landers to the far side of the moon.

  19. The challenge of faecal sludge management in urban areas--strategies, regulations and treatment options.

    PubMed

    Ingallinella, A M; Sanguinetti, G; Koottatep, T; Montanger, A; Strauss, M

    2002-01-01

    In urban centres of industrialising countries, the majority of houses are served by on-site sanitation systems such as septic tanks and unsewered toilets. The faecal sludges (FS) collected from these systems are usually discharged untreated into the urban and peri-urban environment, posing great risks to water resources and to public health. Contrary to wastewater management, the development of strategies to cope with faecal sludges, adapted to the conditions prevailing in developing countries, have long been neglected. The authors describe the current situation and discuss selected issues of FS management. A proposal is made for a rational setting of sludge quality or treatment standards in economically emerging countries. The authors stipulate that regulatory setting should take into account local economic, institutional and technical conditions. Defining suitable treatment options as critical control points in securing adequate sludge quality is better than setting and relying on numerical sludge quality standards. A separate section is devoted to the practice and to regulatory aspects of (faecal) sludge use in Argentina. An overview of treatment options, which may prove sustainable in less industrialized countries is provided. Planted sludge drying beds are one of these options. It has been piloted in Thailand for four years and details on its performance and operation are presented along with data on the hygienic quality of treated biosolids. PMID:12479483

  20. Conceptual approaches for incorporating climatic change into the development of forest management options for sequestering carbon

    SciTech Connect

    King, G.A.

    1993-01-01

    The potential for significant enviromental change over the next 100 years has resulted in efforts to develop mitigation options for reducing the rate of increase of carbon dioxide concentrations in the atmosphere. One of the more promising options is management of forest and agroforestry systems. However, most of the assessments of the potential of forest management options to sequester carbon have not factored in future environmental change (climate and CO2 concentration) into their analyses. Climate and ecological models that could be used to incorporate environmental change into forest mitigation planning efforts are reviewed in the paper in terms of their relative strengths and limitations for this particular application. Recommendations are then made as to how to use the available models to estimate the global and regional potential for sequestering carbon in the terrestrial biosphere, incorporating future environmental change into the analyses. Recommendations are also made as to how to target the most promising regions for reforestation efforts given the likelihood of future environmental change. (Copyright (c) Inter-Research 1993.)

  1. Climate Change, Coral Reef Ecosystems, and Management Options for Marine Protected Areas

    NASA Astrophysics Data System (ADS)

    Keller, Brian D.; Gleason, Daniel F.; McLeod, Elizabeth; Woodley, Christa M.; Airamé, Satie; Causey, Billy D.; Friedlander, Alan M.; Grober-Dunsmore, Rikki; Johnson, Johanna E.; Miller, Steven L.; Steneck, Robert S.

    2009-12-01

    Marine protected areas (MPAs) provide place-based management of marine ecosystems through various degrees and types of protective actions. Habitats such as coral reefs are especially susceptible to degradation resulting from climate change, as evidenced by mass bleaching events over the past two decades. Marine ecosystems are being altered by direct effects of climate change including ocean warming, ocean acidification, rising sea level, changing circulation patterns, increasing severity of storms, and changing freshwater influxes. As impacts of climate change strengthen they may exacerbate effects of existing stressors and require new or modified management approaches; MPA networks are generally accepted as an improvement over individual MPAs to address multiple threats to the marine environment. While MPA networks are considered a potentially effective management approach for conserving marine biodiversity, they should be established in conjunction with other management strategies, such as fisheries regulations and reductions of nutrients and other forms of land-based pollution. Information about interactions between climate change and more “traditional” stressors is limited. MPA managers are faced with high levels of uncertainty about likely outcomes of management actions because climate change impacts have strong interactions with existing stressors, such as land-based sources of pollution, overfishing and destructive fishing practices, invasive species, and diseases. Management options include ameliorating existing stressors, protecting potentially resilient areas, developing networks of MPAs, and integrating climate change into MPA planning, management, and evaluation.

  2. Climate change, coral reef ecosystems, and management options for marine protected areas.

    PubMed

    Keller, Brian D; Gleason, Daniel F; McLeod, Elizabeth; Woodley, Christa M; Airamé, Satie; Causey, Billy D; Friedlander, Alan M; Grober-Dunsmore, Rikki; Johnson, Johanna E; Miller, Steven L; Steneck, Robert S

    2009-12-01

    Marine protected areas (MPAs) provide place-based management of marine ecosystems through various degrees and types of protective actions. Habitats such as coral reefs are especially susceptible to degradation resulting from climate change, as evidenced by mass bleaching events over the past two decades. Marine ecosystems are being altered by direct effects of climate change including ocean warming, ocean acidification, rising sea level, changing circulation patterns, increasing severity of storms, and changing freshwater influxes. As impacts of climate change strengthen they may exacerbate effects of existing stressors and require new or modified management approaches; MPA networks are generally accepted as an improvement over individual MPAs to address multiple threats to the marine environment. While MPA networks are considered a potentially effective management approach for conserving marine biodiversity, they should be established in conjunction with other management strategies, such as fisheries regulations and reductions of nutrients and other forms of land-based pollution. Information about interactions between climate change and more "traditional" stressors is limited. MPA managers are faced with high levels of uncertainty about likely outcomes of management actions because climate change impacts have strong interactions with existing stressors, such as land-based sources of pollution, overfishing and destructive fishing practices, invasive species, and diseases. Management options include ameliorating existing stressors, protecting potentially resilient areas, developing networks of MPAs, and integrating climate change into MPA planning, management, and evaluation. PMID:19636605

  3. 75 FR 41790 - Address Management Services-Elimination of the Manual Card Option for Address Sequencing Services

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-19

    ... 111 Address Management Services--Elimination of the Manual Card Option for Address Sequencing Services... Standards of the United States Postal Service, Domestic Mail Manual (DMM ) 507.8 to eliminate the manual... pricing, which requires address sequencing. For the manual option of Address Sequencing service,...

  4. Land Management Restrictions and Options for Change in Perpetual Conservation Easements

    NASA Astrophysics Data System (ADS)

    Rissman, Adena; Bihari, Menka; Hamilton, Christopher; Locke, Christina; Lowenstein, David; Motew, Melissa; Price, Jessica; Smail, Robert

    2013-07-01

    Conservation organizations rely on conservation easements for diverse purposes, including protection of species and natural communities, working forests, and open space. This research investigated how perpetual conservation easements incorporated property rights, responsibilities, and options for change over time in land management. We compared 34 conservation easements held by one federal, three state, and four nonprofit organizations in Wisconsin. They incorporated six mechanisms for ongoing land management decision-making: management plans (74 %), modifications to permitted landowner uses with discretionary consent (65 %), amendment clauses (53 %), easement holder rights to conduct land management (50 %), reference to laws or policies as compliance terms (47 %), and conditional use permits (12 %). Easements with purposes to protect species and natural communities had more ecological monitoring rights, organizational control over land management, and mechanisms for change than easements with general open space purposes. Forestry purposes were associated with mechanisms for change but not necessarily with ecological monitoring rights or organizational control over land management. The Natural Resources Conservation Service-Wetland Reserve Program had a particularly consistent approach with high control over land use and some discretion to modify uses through permits. Conservation staff perceived a need to respond to changing social and ecological conditions but were divided on whether climate change was likely to negatively impact their conservation easements. Many conservation easements involved significant constraints on easement holders' options for altering land management to achieve conservation purposes over time. This study suggests the need for greater attention to easement drafting, monitoring, and ongoing decision processes to ensure the public benefits of land conservation in changing landscapes.

  5. Factors that influence patient preferences for prostate cancer management options: A systematic review

    PubMed Central

    Showalter, Timothy N; Mishra, Mark V; Bridges, John FP

    2015-01-01

    Purpose We performed a systematic review to evaluate evidence regarding factors that influence patient preferences for management options for localized prostate cancer. Methods We followed a prespecified search protocol (PROSPERO identifier CRD42014009173) to identify studies that evaluated patient preferences for prostate cancer management options for localized prostate cancer. We queried PubMed, the Cochrane Database of Systematic Reviews, Embase, Cumulative Index to Nursing & Allied Health Literature (CINAHL) Plus, and Econ-Lit databases. Two separate reviewers completed the article selection process and review, including coding of study characteristics. Study quality was scored according to the PREFS checklist, which consists of five criteria: Purpose, Respondents, Explanation, Findings, and Significance. Reviewers summarized the primary findings of each article included in the analysis. Results Of the 606 citations identified in the literature search, there were a total of 21 articles that met all selection criteria, reporting results for a total of 4,131 subjects. Themes identified in the studies included: the importance of patient perceptions of treatment efficacy and side effects; the influence of physician recommendations on patient decision-making; and the prioritization of concerns regarding treatment side effects among those men who prefer radiation therapy or active surveillance. The articles had an average PREFS score of 3.4 (standard deviation [SD] 1.0), which is similar to a recent study for breast cancer treatment preferences. Conclusion This systematic review of factors that influence patient preferences for prostate cancer management options identified a small, but high quality, group of articles that satisfied the selection criteria. The available evidence suggests that interventions aimed at informing patients regarding the comparative effectiveness of prostate cancer management alternatives should include the influence of physician

  6. Options for managing impacts of climate change on a deep-sea community

    NASA Astrophysics Data System (ADS)

    Thresher, Ronald E.; Guinotte, John M.; Matear, Richard J.; Hobday, Alistair J.

    2015-07-01

    The deep sea hosts some of the world's largest, oldest, and most sensitive ecosystems. Climate change and ocean acidification are likely to have severe implications for many deep-sea ecosystems and communities, but what, if anything, can be done to mitigate these threats is poorly understood. To begin to bridge this gap, we convened a stakeholder workshop to assess and prioritize options for conserving legislatively protected deep-sea coral reefs off southeast Australia that, without management intervention, are likely to be severely degraded within decades as a result of climate change. Seventeen possible options were explored that span biological, engineering and regulatory domains and that differed widely in their perceived costs, benefits, time to implementation, and risks. In the short term, the highest priority identified is the need to urgently locate and protect sites globally that are, or will become, refugia areas for the coral and its associated community as climate change progresses.

  7. Glenohumeral Joint Preservation: A Review of Management Options for Young, Active Patients with Osteoarthritis

    PubMed Central

    van der Meijden, Olivier A.; Gaskill, Trevor R.; Millett, Peter J.

    2012-01-01

    The management of osteoarthritis of the shoulder in young, active patients is a challenge, and the optimal treatment has yet to be completely established. Many of these patients wish to maintain a high level of activity, and arthroplasty may not be a practical treatment option. It is these patients who may be excellent candidates for joint-preservation procedures in an effort to avoid or delay joint replacement. Several palliative and restorative techniques are currently optional. Joint debridement has shown good results and a combination of arthroscopic debridement with a capsular release, humeral osteoplasty, and transcapsular axillary nerve decompression seems promising when humeral osteophytes are present. Currently, microfracture seems the most studied reparative treatment modality available. Other techniques, such as autologous chondrocyte implantation and osteochondral transfers, have reportedly shown potential but are currently mainly still investigational procedures. This paper gives an overview of the currently available joint preserving surgical techniques for glenohumeral osteoarthritis. PMID:22536514

  8. Estimating option values of solar radiation management assuming that climate sensitivity is uncertain.

    PubMed

    Arino, Yosuke; Akimoto, Keigo; Sano, Fuminori; Homma, Takashi; Oda, Junichiro; Tomoda, Toshimasa

    2016-05-24

    Although solar radiation management (SRM) might play a role as an emergency geoengineering measure, its potential risks remain uncertain, and hence there are ethical and governance issues in the face of SRM's actual deployment. By using an integrated assessment model, we first present one possible methodology for evaluating the value arising from retaining an SRM option given the uncertainty of climate sensitivity, and also examine sensitivities of the option value to SRM's side effects (damages). Reflecting the governance challenges on immediate SRM deployment, we assume scenarios in which SRM could only be deployed with a limited degree of cooling (0.5 °C) only after 2050, when climate sensitivity uncertainty is assumed to be resolved and only when the sensitivity is found to be high (T2x = 4 °C). We conduct a cost-effectiveness analysis with constraining temperature rise as the objective. The SRM option value is originated from its rapid cooling capability that would alleviate the mitigation requirement under climate sensitivity uncertainty and thereby reduce mitigation costs. According to our estimates, the option value during 1990-2049 for a +2.4 °C target (the lowest temperature target level for which there were feasible solutions in this model study) relative to preindustrial levels were in the range between $2.5 and $5.9 trillion, taking into account the maximum level of side effects shown in the existing literature. The result indicates that lower limits of the option values for temperature targets below +2.4 °C would be greater than $2.5 trillion. PMID:27162346

  9. Evaluating options for balancing the water-electricity nexus in California: Part 2--greenhouse gas and renewable energy utilization impacts.

    PubMed

    Tarroja, Brian; AghaKouchak, Amir; Sobhani, Reza; Feldman, David; Jiang, Sunny; Samuelsen, Scott

    2014-11-01

    A study was conducted to compare the technical potential and effectiveness of different water supply options for securing water availability in a large-scale, interconnected water supply system under historical and climate-change augmented inflow and demand conditions. Part 2 of the study focused on determining the greenhouse gas and renewable energy utilization impacts of different pathways to stabilize major surface reservoir levels. Using a detailed electric grid model and taking into account impacts on the operation of the water supply infrastructure, the greenhouse gas emissions and effect on overall grid renewable penetration level was calculated for each water supply option portfolio that successfully secured water availability from Part 1. The effects on the energy signature of water supply infrastructure were found to be just as important as that of the fundamental processes for each option. Under historical (baseline) conditions, many option portfolios were capable of securing surface reservoir levels with a net neutral or negative effect on emissions and a benefit for renewable energy utilization. Under climate change augmented conditions, however, careful selection of the water supply option portfolio was required to prevent imposing major emissions increases for the system. Overall, this analysis provided quantitative insight into the tradeoffs associated with choosing different pathways for securing California's water supply. PMID:25087186

  10. Risk management of liquefied natural gas installations

    NASA Technical Reports Server (NTRS)

    Fedor, O. H.; Parsons, W. N.; Coutinho, J. De C.

    1976-01-01

    In connection with the construction of four major liquefied natural gas (LNG) facilities in New York City, the New York City Fire Commissioner has asked NASA for assistance. It was decided that the Kennedy Space Center should develop a risk management system (RMS) for the use of the New York Fire Department (NYFD). The RMS provides for a published set of safety regulations by the NYFD. A description of the RMS is presented as an example of an application of aerospace technology to a civilian sector, namely LNG facilities.

  11. Sustainable approaches for minimizing biosolids production and maximizing reuse options in sludge management: A review.

    PubMed

    Joo, Sung Hee; Dello Monaco, Francesca; Antmann, Eric; Chorath, Philip

    2015-08-01

    Sludge generation during wastewater treatment is inevitable even with proper management and treatment. Yet proper handling and disposal of sludge are still challenging in terms of treatment cost, presence of recalcitrant contaminants of concern, sanitary issues, and public acceptance. Conventional disposal methods (i.e. landfilling, incineration) have created concerns in terms of legislative restrictions and community perception, incentivizing consideration of substitute sludge management options. Furthermore, with proper treatment, biosolids from sludge, rich in organic materials and nutrients, could be utilizable as fertilizer. Despite the challenges of dealing with sludge, no review has dealt with integrated source reduction and reuse as the best sustainable management practices for sludge treatment. In this review, we present two main approaches as potentially sustainable controls: (i) pretreatment for minimizing extensive sludge treatment, and (ii) recycling and reuse of residual sludge. Drawing on these approaches, we also suggest strategies for efficient pretreatment mechanisms and residual reuse, presenting ideas for prospective future research. PMID:26001503

  12. Women's experiences of three early miscarriage management options a qualitative study

    PubMed Central

    Smith, Lindsay F; Frost, Julia; Levitas, Ruth; Bradley, Harriet; Garcia, Jo

    2006-01-01

    Background Miscarriage affects around one in six pregnancies. Much research has taken place identifying the consequences of this for parents but is mainly quantitative. Of the limited qualitative studies, none have explored women's experiences of the methods of miscarriage management received. Aim To assess the social and personal impact of different management methods (expectant, medical and surgical) on women's experience of first trimester miscarriage. Design of study Qualitative interviews using a topic guide with a purposive cohort of four categories of women (each management method plus non-participants) 6 months to 1 year after first trimester miscarriage. Focus groups with both research participants and health workers. Setting Women from three hospitals in the South West of England that participated in the Miscarriage Treatment (MIST) trial. Method Seventy-two interviews were undertaken between September 1999 and June 2000. There were also five focus groups (47 participants) and two feedback sessions (8 participants) with written feedback from 12 women. Interviews lasted 0.5–2.5 hours generating over 2000 A4 pages of transcripts. The transcripts were analysed for common themes, using standard proformas, which were filled in by individual team members and then discussed by the whole research team. Iterative readings in the light of new emerging issues ensured that new themes could be identified throughout the analytical process. All transcripts were then encoded for the identified themes using NUDIST. Results Common themes emerged across all management options although some were specific to just one or two management options. The five major themes arising out of the data analysis were: intervention; experiences of care; finality; the ‘baby’; and pain and bleeding. Conclusions Women's experiences and beliefs vary widely and their preferences need to be considered in their early miscarriage management. The three methods have different benefits and

  13. Anorectal Injuries due to Foreign Bodies: Case Reports and Review of the Management Options

    PubMed Central

    Karateke, Faruk; Das, Koray; Ozyazici, Sefa; Menekse, Ebru; Koseoglu, Zikret; Karcioglu, Ozgur

    2013-01-01

    Anorectal injuries due to autoerotic activity with rectal foreign bodies were identified in four male patients. The objects were bottle in one patient, glasses in two patients, and showerhead in one patient. Foreign bodies were extracted within lithotomy position after anal dilatation, under general anesthesia in 3 patients. One patient presented with peritoneal irritation and had a diagnosis of rectal perforation. He underwent transanal rectal repair with proximal fecal diversion. In this paper we described 4 patients who had anorectal injuries due to autoerotic activity with foreign bodies and reviewed the management options in literature. PMID:23533918

  14. Employer-based coverage and medical travel options: lessons for healthcare managers.

    PubMed

    Karuppan, Corinne Marie

    2014-01-01

    Outbound medical travel (MT) involves U.S. patients going abroad to seek medical care. Over the past decade, there has been much discussion about MT's broadening appeal to several segments of U.S. healthcare consumers, but little is known about its penetration in the employer-based coverage (EBC) marketplace. The objectives of this article are to fill this gap and identify (1) the current status of MT options in EBC, (2) the differences between adopters and nonadopters of MT options, and (3) the factors that impede adoption. The results were obtained from a nationwide survey of human resources (HR) professionals making decisions regarding medical benefits. In this sample (n = 608), 16.8% of the respondents offered outbound MT options to their employees, often bypassing their insurance providers. Besides benefiting from a strong HR function, these organizations tended to be more involved in global business transactions, more open to change, more sensitive to cost savings, and more flexible in implementing administrative innovations than nonadopters were. An organizational climate conducive to innovation may explain their propensity to downplay the importance of well-known obstacles to implementation, such as the effort required to make changes, an emphasis on short-term goals, and the fear of liability. The lessons to be learned by U.S. healthcare managers are clear. To attract a value-conscious market, they must offer an attractive package of outstanding quality (clinical outcomes and patient experience) at competitive costs. Operational excellence may thus be the key to slowing the inevitable diffusion of MT options in EBC and maintaining or even expanding the U.S. market share of elective surgeries. PMID:24988676

  15. A System Dynamics Approach for the Selection of Contaminated Land Management Options

    NASA Astrophysics Data System (ADS)

    McKnight, U. S.; Kuebert, M.; Finkel, M.; Bieg, M.

    2006-12-01

    Large-scale contaminated land and groundwater is a widespread problem that can severely impact human health, the environment and the economy at many urban sites all over the world. Usually a considerable number of potential management solutions exist at each of these sites. A detailed investigation of all these options, however, is not economically feasible which makes streamlining of the planning and decision process a mandatory requirement. Decisions to be taken should be made as early as possible in order to reduce expenditures on site investigation. Therefore, a tiered decision-making procedure is required, including (i) identification and prioritization of focal areas of risks, (ii) feasibility screening of remediation targets and available management alternatives to narrow the range of possible options for (iii) subsequent detailed investigations of only a select group of preferable options. For each of these elements, tailored decision and investigation concepts are required. These concepts and applied methods should be specifically adapted to the type and scale of the particular decision to be taken- more target-oriented, cost-efficient investigation programs, as well as model-based assessment methods are needed (Ruegner et al. 2006). A gap exists within this framework with respect to preliminary assessment methodologies representing the first decision level. To fill this gap, a new system dynamics approach has been developed that represents the system of source- pathway-receptor sequences by means of a mass flux model. The dynamics are governed by the effects of possible remedial actions, which are described as mass flux change over time (Serapiglia et al. 2005). This approach has been implemented in the preliminary evaluation tool CARO-plus (Cost-efficiency Assessment of Remediation Options) that models the effects of potential remedial actions, including tackling the contaminant source and managing the groundwater plume. The model represents the causal

  16. A comparison of costs associated with utility management options for dry active waste

    SciTech Connect

    Hornibrook, C.

    1995-12-31

    The economics of low level waste management is receiving more attention today than ever before. This is due to four factors: (1) the increases in the cost of processing of these wastes; (2) increases in the cost of disposal; (3) the addition of storage costs for those without access to disposal; and (4) the increasing competitive nature of the electric generation industry. These pressures are forcing the industry to update it`s evaluation of the mix of processing that will afford it the best long term economics and minimize it`s risks for unforeseen costs. Whether disposal is available or not, all utilities face the same challenge of minimizing the costs associated with the management of these wastes. There are a number of variables that will impact how a utility manages their wastes but the problem is the uncertainty of what will actually happen, i.e., will disposal be available, when and at what cost. Using the EPRI-developed WASTECOST: DAW code, this paper explores a variety of LLW management options available to utilities. Along with providing the costs and benefits, other technical considerations which play an important part in the management of these wastes are also addressed.

  17. Management of frontotemporal dementia: targeting symptom management in such a heterogeneous disease requires a wide range of therapeutic options

    PubMed Central

    Jicha, Gregory A; Nelson, Peter T

    2011-01-01

    SUMMARY There are no US FDA-approved therapies for the management of frontotemporal dementia (FTD). Evidence-based medicine that would support a FDA indication for the treatment of FTD requires large-scale, randomized, double-blind, placebo-controlled trials that do not currently exist. Progress in obtaining approval and therapeutic indications for FTD has been severely hampered by the heterogeneity of clinical and pathological phenotypes seen in various FTD disease states. These issues are often misinterpreted by clinicians, caregivers and patients suggesting that potential treatment options are nonexistent for this devastating disease. This article discusses these issues in the context of recent studies and publications investigating therapeutic options in FTD, and further suggests a rationale for individualized therapy in FTD. Targeting the myriad of symptoms seen in FTD requires recognition of such symptoms that may play primary or secondary roles in the spectrum of deficits that lead to functional disability in FTD, and the availability of a wide range of therapeutic options that may be helpful in alleviating such symptomatology. Fortunately, agents targeting the many cognitive, behavioral, psychiatric and motor symptoms that can be seen in FTD are readily available, having been previously developed and approved for symptomatic benefit in other disease states. In contrast to the widespread belief that beneficial treatments are not available for FTD today, our therapeutic armament is stocked with pharmacological tools that may improve quality of life for those suffering from this devastating and incurable class of degenerative diseases. PMID:21927623

  18. Achieving Resource Conservation in Electronic Waste Management: A Review of Options Available to Developing Countries

    NASA Astrophysics Data System (ADS)

    Chidi Nnorom, Innocent; Osibanjo, Oladele; Onyedikachi Nnorom, Stanley

    Large quantities of waste electronic devices (e-waste) at their end-of-life, generated internally or imported illegally from developed countries, are currently being managed in the developing countries, through low-end means such as crude backyard recycling and disposal at unlined landfills or open dumps. The extension of the lifespan of electronic devices through reuse options such as repair, reconditioning and remanufacturing should be a priority in the management of electronic waste in developing countries considering the near absence of state-of-the-art recycling facilities in these countries. Life extension through product and component reuse is especially critical to electronic products because in recent years, electronics have increased in technological complexity, with new product innovations and ever shortening product life expectancy. For many products, environmentalists assume that reuse is environmentally beneficial because it replaces the manufacturing and purchase of new goods. However, on the contrary, manufacturers may oppose this type of reuse for the same reason. There is an urgent need to control the trans-boundary movement of electronic scrap especially to countries without established recycling facilities. Importations of secondhand electronics make such devices available to those who cannot afford new products. However, an international method of testing and certification is needed to ensure that exported secondhand devices are functional. Establishment of formal recycling facilities for e-waste in the developing countries will ensure resource reutilization with both economical and ecological gains. This study reviews options available in working towards eco-efficient management of e-waste in developing countries in the light of the present low-end management practices.

  19. Sustainability and Energy Development: Influences of Greenhouse Gas Emissions Reduction Options on Water Use in Energy Production

    SciTech Connect

    D. Craig Cooper; Gerald Sehlke

    2012-01-01

    Climate change mitigation strategies cannot be evaluated solely in terms of energy cost and greenhouse gas (GHG) mitigation potential. Maintaining GHGs at a 'safe' level will require fundamental change in the way we approach energy production, and a number of environmental, economic, and societal factors will come into play. Water is an essential component of energy production, and water resource constraints (e.g., insufficient supplies and competing ecological and anthropogenic needs) will limit our options for producing energy and for reducing GHG emissions. This study evaluates these potential constraints from a global perspective by revisiting the 'climate wedges' proposal of Pacala and Sokolow [1], and evaluating the potential water impacts of the 'wedges' associated with energy production. Results indicate that there is a range of water impacts, with some options reducing water demand while others increase water demand. Mitigation options that improve energy conversion and end-use efficiency have the greatest potential for reducing water resources impacts. These options provide 'win-win-win' scenarios for reducing GHG emissions, lowering energy costs and reducing water demand. Thet may merit higher priority than alternative options that emphasize deploying new low-carbon energy facilities or modifying existing facilities with energy intensive GHG mitigation technologies to reduce GHG emissions. While the latter can reduce GHG emissions, they will typically increase energy costs and water impacts.

  20. Greenhouse gas accounting and waste management.

    PubMed

    Gentil, Emmanuel; Christensen, Thomas H; Aoustin, Emmanuelle

    2009-11-01

    Accounting of emissions of greenhouse gas (GHG) is a major focus within waste management. This paper analyses and compares the four main types of GHG accounting in waste management including their special features and approaches: the national accounting, with reference to the Intergovernmental Panel on Climate Change (IPCC), the corporate level, as part of the annual reporting on environmental issues and social responsibility, life-cycle assessment (LCA), as an environmental basis for assessing waste management systems and technologies, and finally, the carbon trading methodology, and more specifically, the clean development mechanism (CDM) methodology, introduced to support cost-effective reduction in GHG emissions. These types of GHG accounting, in principle, have a common starting point in technical data on GHG emissions from specific waste technologies and plants, but the limited availability of data and, moreover, the different scopes of the accounting lead to many ways of quantifying emissions and producing the accounts. The importance of transparency in GHG accounting is emphasised regarding waste type, waste composition, time period considered, GHGs included, global warming potential (GWP) assigned to the GHGs, counting of biogenic carbon dioxide, choice of system boundaries, interactions with the energy system, and generic emissions factors. In order to enhance transparency and consistency, a format called the upstream-operating-downstream framework (UOD) is proposed for reporting basic technology-related data regarding GHG issues including a clear distinction between direct emissions from waste management technologies, indirect upstream (use of energy and materials) and indirect downstream (production of energy, delivery of secondary materials) activities. PMID:19808731

  1. Double J stenting: A rewarding option in the management of emphysematous pyelonephritis

    PubMed Central

    Das, Debiprasad; Pal, Dilip Kumar

    2016-01-01

    Context: Emphysematous pyelonephritis (EPN) is an acute necrotizing inflammation of renal parenchyma and peri-nephric tissue characterized by gas formation. In this study, we evaluated the outcome of EPN cases by medical management with or without renal decompression. Materials and Methods: We have observed prospectively 15 cases of EPN admitted in our institute in respect to age, sex, mode of presentation, presence of comorbidity, laboratory profile, urine-analysis, and outcome after medical management and drainage procedures. Results: All patients improved on medical management and drainage procedure such as JJ stenting and percutaneous nephrostomy. No mortality noted in our 15 cases of EPN. Conclusion: Emphysematous pyelonephritis can be managed conservatively by DJ stenting, wcich is a less morbid procedure or percutaneous nephrostomy with proper antibiotics and adequate glycemic control. PMID:27453644

  2. A Many-Objective Optimization of Supply and Demand Management Options for the Thames Basin

    NASA Astrophysics Data System (ADS)

    Matrosov, Evgenii S.; Huskova, Ivana; Kasprzyk, Joseph R.; Harou, Julien J.; Reed, Patrick M.

    2013-04-01

    In this study we link a water resource management simulator and a many-objective evolutionary optimization algorithm to reveal the trade-offs mapped out by the set of Pareto-optimal water supply portfolios. The approach is applied to a case-study involving the water stressed Thames basin in South East England which includes the city of London. Such a many-objective approach could be used by regulators and stakeholders to supplement current water resource system planning which uses single-objective least-cost optimization. We consider both infrastructure additions and demand management options to produce possible water system portfolios that satisfy the future demand trajectory and meet regulatory performance constraints. Possible infrastructure options explored in the case study include a new reservoir, water transfers, conjunctive use of groundwater, wastewater reuse and brackish groundwater desalination. Demand management options include leakage reduction, the introduction of seasonal tariffs with compulsory metering and efficiency improvements. System performance is evaluated using quantitative performance measures that minimize costs and energy use while maximizing engineering and environmental performance, subject to supply reliability constraints set by the local water utility and the Environment Agency regulator. We use many-objective visual analytics to explore the Pareto approximate trade-off surfaces that show the tradeoffs between engineering, cost, social and environmental performance measures and interactively interrogate the impact of the infrastructure portfolios on the performance measures. Using trusted realistic simulators embedded into global optimzers enables the consideration of non-linear and rule-based physical and management processes that are integral to accurately describing real water systems. The Thames basin is modeled using a generalized computationally efficient open-source water resource simulator, the Interactive River

  3. User perceptions on coastal resource state and management options in Curaçao.

    PubMed

    Debrot, A O; Nagelkerken, I

    2000-12-01

    Public environmental awareness and support for management measures are key determinants of the scope for successful implementation of natural resource management. To assess user perceptions and opinions on resource state and potential management options for the coastal zone of Curaçao, we queried 250 coastal resource users from around the island (sport divers, part-time artisanal fishermen and recreational boaters) using questionnaires. There is wide awareness of a long-term decline in coastal resource condition as measured by various indicators. Even among fishermen there was wide awareness of anthropogenic contributors to the decline, broad agreement of management measures required and a general willingness to contribute to management by means of annual license fees. Some of the more salient findings include the endorsement by fishermen of the current ban on spearfishing (81%), the regulation of the beach seine fishery for scad (77%), the introduction of fish reserves (72%), special protection for sea turtles (90%), conch (82%), and lobsters (72%), and notable support for gradual elimination of trap fisheries (45%). Also, both divers (65%) and boaters (92%) expressed the importance to them of an attractive coastline, with both groups expressing preference for natural (un-built) coastline (>74%) above other categories. Management based on the concept "user pays", as already implemented in the Netherlands Antilles on Saba and Bonaire, is well supported by the resource user public. A review of other main constraints such as finances and institutional capacity, shows that conditions are quite favorable for implementation of new legislation. Modem coral reef management is urgently needed in Curaçao to safeguard a key natural resource and concerted action is called for on the part of government agencies, legislators and elected officials. PMID:15266797

  4. Placing the power of real options analysis into the hands of natural resource managers - taking the next step.

    PubMed

    Nelson, Rohan; Howden, Mark; Hayman, Peter

    2013-07-30

    This paper explores heuristic methods with potential to place the analytical power of real options analysis into the hands of natural resource managers. The complexity of real options analysis has led to patchy or ephemeral adoption even by corporate managers familiar with the financial-market origins of valuation methods. Intuitively accessible methods for estimating the value of real options have begun to evolve, but their evaluation has mostly been limited to researcher-driven applications. In this paper we work closely with Bush Heritage Australia to evaluate the potential of real options analysis to support the intuitive judgement of conservation estate managers in covenanting land with uncertain future conservation value due to climate change. The results show that modified decision trees have potential to estimate the option value of covenanting individual properties while time and ongoing research resolves their future conservation value. Complementing this, Luehrman's option space has potential to assist managers with limited budgets to increase the portfolio value of multiple properties with different conservation attributes. PMID:23702285

  5. 41 CFR 102-194.30 - What role does my agency play in the Standard and Optional Forms Management Program?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., the Architectural and Transportation Barriers Compliance Board (Access Board) Standards (36 CFR part... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What role does my agency... What role does my agency play in the Standard and Optional Forms Management Program? Your agency...

  6. Non-deposit system option for waste management on small islands.

    PubMed

    Vilms, Monica; Voronova, Viktoria

    2016-08-01

    This paper analyses waste management on small islands (on a global scale these are micro-islands). In the context of the paper, small islands are islands that have an area less than 50 km(2) The study presents an overview of the problems connected with waste transport from islands to the mainland. Waste generation on islands is very much related to tourists. If tourists do not handle waste properly, it will cause problems. Four small Estonian islands in the range of 3-19 km(2) are studied in detail. For these and other small islands, the main problem is the waste produced by tourists, or related to tourists and waste transport to the mainland. Currently, the local municipality has to arrange and finance waste transport. In fact, and based on the polluter-pays principle, the tourists should bear the cost of waste management. There are different tax options available in order to collect the money from tourists - waste tax, harbour tax, tourist tax, donations, environmental tax and others. The study results revealed that the best possible solution for Estonian islands may be a non-deposit system - including an additional charge on ferry ticket prices. The extra money should cover the costs of waste management and waste shipping. The tourists arriving in their own boats should pay a harbour tax, which includes a waste tax to compensate for the cost of waste management. PMID:27344037

  7. Greenhouse gas budgets of managed European grasslands

    NASA Astrophysics Data System (ADS)

    Ammann, C.; Horváth, L.; Jones, S. K.

    2012-04-01

    Greenhouse gas exchange of grasslands are directly and indirectly related to the respective carbon (C) and nitrogen (N) budget. Within the framework of the NitroEurope project we investigated the greenhouse gas, carbon, and nitrogen budgets of four European grassland systems over several years: Easter Bush (UK), Oensingen intensive and extensive (CH), and Bugac (HU). They span contrasting climatic conditions, management types (grazing, cutting) and intensity. While Easter Bush (pasture) and Oensingen int. (meadow) were intensively managed and received a considerable amount of fertiliser, the unfertilised sites Bugac (pasture) and Oensingen ext. (meadow) depended on atmospheric N input (wet and dry deposition) and biological N fixation. The experimental results of the four sites were also compared to published GHG fluxes of other European grasslands. While the ecosystem CO2 exchange was measured on the field scale with the eddy covariance method, the soil fluxes of the other greenhouse gases CH4 and N2O have been detected generally by means of static chambers (only occasional application of eddy covariance). The emission of CH4 by grazing ruminant resulting from enteric fermentation was estimated by animal type specific emission factors. For characterizing the total GHG effect of the grassland sites, the contributions of the different GHGs were normalised to CO2-equivalents. Except for Oensingen ext., all sites showed positive C budgets (sequestration). The observed positive correlation between C and N sequestration (with a ratio between 10 and 20) agrees with studies reported in the literature. The magnitude of N2O emission depended mainly on management intensity (fertiliser input) and on the soil moisture conditions. Whereas for the Oensingen and the Bugac sites, the total GHG budget was dominated by the carbon budget, for Easter Bush the combined effect of N2O and CH4 emission (including animal enteric fermentation) was in the same order of magnitude as the

  8. Greenhouse gas emission impacts of alternative-fueled vehicles: Near-term vs. long-term technology options

    SciTech Connect

    Wang, M.Q.

    1997-05-20

    Alternative-fueled vehicle technologies have been promoted and used for reducing petroleum use, urban air pollution, and greenhouse gas emissions. In this paper, greenhouse gas emission impacts of near-term and long-term light-duty alternative-fueled vehicle technologies are evaluated. Near-term technologies, available now, include vehicles fueled with M85 (85% methanol and 15% gasoline by volume), E85 (85% ethanol that is produced from corn and 15% gasoline by volume), compressed natural gas, and liquefied petroleum gas. Long-term technologies, assumed to be available around the year 2010, include battery-powered electric vehicles, hybrid electric vehicles, vehicles fueled with E85 (ethanol produced from biomass), and fuel-cell vehicles fueled with hydrogen or methanol. The near-term technologies are found to have small to moderate effects on vehicle greenhouse gas emissions. On the other hand, the long-term technologies, especially those using renewable energy (such as biomass and solar energy), have great potential for reducing vehicle greenhouse gas emissions. In order to realize this greenhouse gas emission reduction potential, R and D efforts must continue on the long-term technology options so that they can compete successfully with conventional vehicle technology.

  9. Current and future options for the management of phantom-limb pain.

    PubMed

    Knotkova, Helena; Cruciani, Ricardo A; Tronnier, Volker M; Rasche, Dirk

    2012-01-01

    Phantom-limb pain (PLP) belongs among difficult-to-treat chronic pain syndromes. Treatment options for PLP are to a large degree implicated by the level of understanding the mechanisms and nature of PLP. Research and clinical findings acknowledge the neuropathic nature of PLP and also suggest that both peripheral as well as central mechanisms, including neuroplastic changes in central nervous system, can contribute to PLP. Neuroimaging studies in PLP have indicated a relation between PLP and the neuroplastic changes. Further, it has been shown that the pathological neuroplastic changes could be reverted, and there is a parallel between an improvement (reversal) of the neuroplastic changes in PLP and pain relief. These findings facilitated explorations of novel neuromodulatory treatment strategies, adding to the variety of treatment approaches in PLP. Overall, available treatment options in PLP include pharmacological treatment, supportive non-pharmacological non-invasive strategies (eg, neuromodulation using transcranial magnetic stimulation, visual feedback therapy, or motor imagery; peripheral transcutaneous electrical nerve stimulation, physical therapy, reflexology, or various psychotherapeutic approaches), and invasive treatment strategies (eg, surgical destructive procedures, nerve blocks, or invasive neuromodulation using deep brain stimulation, motor cortex stimulation, or spinal cord stimulation). Venues of further development in PLP management include a technological and methodological improvement of existing treatment methods, an implementation of new techniques and products, and a development of new treatment approaches. PMID:22457600

  10. Capturing and Explaining Preference Heterogeneity for Wetland Management Options in the Kilombero Valley, Tanzania

    NASA Astrophysics Data System (ADS)

    Speelman, Stijn; Mombo, Felister; Vandermeulen, Valerie; Phillip, Damas; Van Huylenbroeck, Guido

    2015-01-01

    Wetland degradation has recently received considerable research attention. Although wetlands are valuable ecosystems, their actual value is difficult to measure because the services they provide often do not have market values. The current study seeks to investigate the preferences for wetland management options in the Kilombero Valley, central Tanzania using choice modeling. The results show that both respondents from the Kilombero Valley and Morogoro Municipality desire improvements in the condition of the wetlands. This indicates that the ongoing degradation is not socially optimal. A second finding is that the preferences for wetland conservation are heterogeneous and can be linked to livelihood characteristics. Communities living in the area, for example, are highly dependent on the wetland for their livelihood and would be impacted by conservation measures. Therefore, in order to reduce the pressure on wetlands, it is necessary and imperative to explore the options for alternative income-generating activities or to focus, for example, on technologies to improve efficiency and effectiveness in crop production.

  11. Capturing and explaining preference heterogeneity for wetland management options in the Kilombero Valley, Tanzania.

    PubMed

    Speelman, Stijn; Mombo, Felister; Vandermeulen, Valerie; Phillip, Damas; Van Huylenbroeck, Guido

    2015-01-01

    Wetland degradation has recently received considerable research attention. Although wetlands are valuable ecosystems, their actual value is difficult to measure because the services they provide often do not have market values. The current study seeks to investigate the preferences for wetland management options in the Kilombero Valley, central Tanzania using choice modeling. The results show that both respondents from the Kilombero Valley and Morogoro Municipality desire improvements in the condition of the wetlands. This indicates that the ongoing degradation is not socially optimal. A second finding is that the preferences for wetland conservation are heterogeneous and can be linked to livelihood characteristics. Communities living in the area, for example, are highly dependent on the wetland for their livelihood and would be impacted by conservation measures. Therefore, in order to reduce the pressure on wetlands, it is necessary and imperative to explore the options for alternative income-generating activities or to focus, for example, on technologies to improve efficiency and effectiveness in crop production. PMID:25403812

  12. Framework for managing wastes from oil and gas exploration and production (E&P) sites.

    SciTech Connect

    Veil, J. A.; Puder, M. G.; Environmental Science Division

    2007-09-15

    Oil and gas companies operate in many countries around the world. Their exploration and production (E&P) operations generate many kinds of waste that must be carefully and appropriately managed. Some of these wastes are inherently part of the E&P process; examples are drilling wastes and produced water. Other wastes are generic industrial wastes that are not unique to E&P activities, such as painting wastes and scrap metal. Still other wastes are associated with the presence of workers at the site; these include trash, food waste, and laundry wash water. In some host countries, mature environmental regulatory programs are in place that provide for various waste management options on the basis of the characteristics of the wastes and the environmental settings of the sites. In other countries, the waste management requirements and authorized options are stringent, even though the infrastructure to meet the requirements may not be available yet. In some cases, regulations and/or waste management infrastructure do not exist at all. Companies operating in these countries can be confronted with limited and expensive waste management options.

  13. Environmental contamination at Finnish shooting ranges--the scope of the problem and management options.

    PubMed

    Sorvari, Jaana; Antikainen, Riina; Pyy, Outi

    2006-07-31

    In Finland, shooting ranges are among the most common activities causing soil contamination. According to our study based on questionnaires and previous regional surveys, the total number of Finnish outdoor shooting ranges is between 2000 and 2500. Most of the ranges are small and only ca. 5% exceed 20 ha. Almost a third of the ranges can cause a groundwater pollution risk, while only few cause an immediate health risk. In the first instance, 50-60 shooting ranges identified as being high-risk areas should be investigated in detail. At present, the risk management options at Finnish shooting ranges are very limited. Hence, soil excavation combined with disposal is the most common remediation technique. Some of the remediation methods used in other countries have been proven unsuitable in Finnish conditions. Therefore, new, feasible, cost-effective and economical remediation technologies are needed. To exclude future contamination, a total ban of lead shot would be the most effective way. PMID:16458952

  14. Review of biosolids management options and co-incineration of a biosolid-derived fuel.

    PubMed

    Roy, Murari Mohon; Dutta, Animesh; Corscadden, Kenny; Havard, Peter; Dickie, Lucas

    2011-11-01

    This paper reviews current biosolids management options, and identifies incineration as a promising technology. Incineration is attractive both for volume reduction and energy recovery. Reported emissions from the incineration of biosolids were compared to various regulations to identify the challenges and future direction of biosolids incineration research. Most of the gaseous and metal emissions were lower than existing regulations, or could be met by existing technologies. This paper also presents the results of an experimental study to investigate the potential use of biosolids for co-incineration with wood pellets in a conventional wood pellet stove. Pilot scale combustion tests revealed that co-incineration of 10% biosolids with 90% premium grade wood pellets resulted in successful combustion without any significant degradation of efficiency and emissions. PMID:21763120

  15. A new therapeutic option for postoperative pain management with oxycodone HCI injection.

    PubMed

    Choi, Byung Moon

    2016-06-01

    Fentanyl is the most commonly used opioid analgesic in intravenous patient-controlled analgesia (IV PCA) in Korea. IV oxycodone was approved for postoperative IV PCA by the Ministry of Food and Drug Safety of Korea in 2013. The approved dosage regimen for postoperative pain relief with IV oxycodone is IV bolus loading of 2 mg followed by PCA composed of demand boluses of 1 mg and no background infusion with an oxycodone concentration of 1 mg/ml. However, a simulation study indicated that the minimum effective analgesic concentration (MEAC, as indicated by relief of pain by administering rescue analgesics) of oxycodone was reached most quickly with a higher loading dose of 0.1 mg/kg and IV PCA with background infusion. Oxycodone is a therapeutic option as an analgesic for postoperative pain management. It is necessary to reduce the analgesic dose of oxycodone in elderly patients because metabolic clearance decreases with age. PMID:27274364

  16. Management options for children with attention-deficit/hyperactivity disorder: a regional perspective on value.

    PubMed

    Ollendorf, Daniel A; Migliaccio-Walle, Kristen; Colby, Jennifer A; Pearson, Steven D

    2013-05-01

    Use of comparative effectiveness information in local healthcare decisions can be confounded by variations in practice, barriers to access and population demographics. The New England Comparative Effectiveness Public Advisory Council was convened as a public deliberative panel that considers evidence on the comparative clinical effectiveness and comparative value of a variety of therapeutic interventions. The council is tasked with making summary judgments on the evidence and recommendations for applying the evidence in medical and drug coverage policy, as well as initiating educational efforts for patients and clinicians. The New England Comparative Effectiveness Public Advisory Council met in June 2012 to discuss management options for attention-deficit/hyperactivity disorder, guided by a recent comparative effectiveness review from the Agency for Healthcare Research and Quality and supplementary economic analyses conducted by the Institute for Clinical and Economic Review. This article summarizes the deliberations and reflects on lessons learned regarding use of region-specific economic analyses to guide decision-making. PMID:24236625

  17. A new therapeutic option for postoperative pain management with oxycodone HCI injection

    PubMed Central

    2016-01-01

    Fentanyl is the most commonly used opioid analgesic in intravenous patient-controlled analgesia (IV PCA) in Korea. IV oxycodone was approved for postoperative IV PCA by the Ministry of Food and Drug Safety of Korea in 2013. The approved dosage regimen for postoperative pain relief with IV oxycodone is IV bolus loading of 2 mg followed by PCA composed of demand boluses of 1 mg and no background infusion with an oxycodone concentration of 1 mg/ml. However, a simulation study indicated that the minimum effective analgesic concentration (MEAC, as indicated by relief of pain by administering rescue analgesics) of oxycodone was reached most quickly with a higher loading dose of 0.1 mg/kg and IV PCA with background infusion. Oxycodone is a therapeutic option as an analgesic for postoperative pain management. It is necessary to reduce the analgesic dose of oxycodone in elderly patients because metabolic clearance decreases with age. PMID:27274364

  18. Pain management following spinal surgeries: An appraisal of the available options

    PubMed Central

    Bajwa, Sukhminder Jit Singh; Haldar, Rudrashish

    2015-01-01

    Spinal procedures are generally associated with intense pain in the postoperative period, especially for the initial few days. Adequate pain management in this period has been seen to correlate well with improved functional outcome, early ambulation, early discharge, and preventing the development of chronic pain. A diverse array of pharmacological options exists for the effective amelioration of post spinal surgery pain. Each of these drugs possesses inherent advantages and disadvantages which restricts their universal applicability. Therefore, combination therapy or multimodal analgesia for proper control of pain appears as the best approach in this regard. The current manuscript discussed the pathophysiology of postsurgical pain including its nature, the various tools for assessment, and the various pharmacological agents (both conventional and upcoming) available at our disposal to respond to post spinal surgery pain. PMID:26288544

  19. Surgical management of cholesteatoma: the two main options and the third way--atticotomy/limited mastoidectomy.

    PubMed

    Nikolopoulos, T P; Gerbesiotis, P

    2009-09-01

    Chronic otitis media with cholesteatoma is considered an "unsafe" ear and generally requires surgical management. This is particularly challenging in children due to anatomical, pathophysiological and social reasons. There are different approaches for this objective. The two main options are the canal wall up and canal wall down mastoidectomy. The aim of this article is to compare the advantages and disadvantages of canal wall up and canal wall down method and present the third way of surgical management: the inside-outside approach through an endaural incision. This technique includes atticotomy, atticoantrostomy or mastoidectomy (mostly very limited) according to the size and location of the cholesteatoma. This technique contributes to the successful surgical management of cholesteatoma, eradicating the disease with the creation of small, dry, self-cleaning cavities and no pinna protrusion. Moreover, there is no need for meatoplasty or obliteration. However, we should never forget that in ear surgery the choice of the operative procedure should take into account the needs of the patient, the extent of the disease, and the surgeon's experience. PMID:19545913

  20. Toward a protocol for quantifying the greenhouse gas balance and identifying mitigation options in smallholder farming systems

    NASA Astrophysics Data System (ADS)

    Rosenstock, T. S.; Rufino, M. C.; Butterbach-Bahl, K.; Wollenberg, E.

    2013-06-01

    ). In that way, the research captures the balance of benefits between the private landholder and the global public good. Joint assessment of food production and emissions may produce optimal management strategies that balance the competing demands of food production and climate stabilization. For example, nitrous oxide emissions per unit of product are lowest at intermediate (not the lowest) fertilization rates (Van Groenigen et al 2010) which differs from the optimal strategy for reducing emissions per unit area. Costs associated with collecting the additional data are likely to be small relative to the operational budget for GHG field research and could viably become standard practice. Cost-differentiated measurements . Potential end users of the protocol are diverse in their purpose, resources available, and capacity to carry out research. For example, development organizations may want to determine the relative difference in emission impacts between mitigation options while governments may be interested in quantification of impacts across landscapes to develop Nationally Appropriate Mitigation Actions. The most useful approach to quantification therefore lies at the nexus among key constraints: objectives, resources, and capacity. The protocol develops a system of 'tiered' entry points for greenhouse gas accounting, with explicit attention directed toward the uncertainty induced from the various measurement selections. The protocol will include decision pathways to help users quickly determine the quantification options suitable for their goals and constraints to optimize the relationship among accuracy, costs, and scale. The CCAFS-CGIAR protocol is being developed and field-tested in mixed crop-livestock systems of Kenya and intensive rice production in the Philippines, with plans to expand to other sites and agroecosystems in the next year. These initial pilot projects provide a trial of the approach and methods, highlighting technical gaps and promising

  1. The management of bilateral posterior fracture dislocations of the shoulder: a case series illustrating management options

    PubMed Central

    Robinson, Peter W; Packham, Iain; Crowther, Mark

    2016-01-01

    Background Although dislocation of the shoulder is a relatively common event, the overwhelming majority of injuries are anterior. Posterior shoulder dislocation is more uncommon, comprising between 3% and 5% of all shoulder dislocations. One percent of shoulder dislocations involve a fracture, whereas only 0.9% of the 1500 cases reported by Neer (J Bone Joint Surg Am 1970; 52:1077–89; J Bone Joint Surg Am 1970; 52:1090–103) concerned posterior fracture dislocations. Bilateral posterior fracture dislocation is an even rarer event, comprising just 5% of all posterior fracture dislocations. Given the rarity and relative poor outcome often observed after these severe injuries, it is important that upper limb function is optimized. Methods Bilateral posterior fracture dislocations of the shoulder pose a difficult clinical challenge that requires careful management planning. To date, there have been three isolated case reports of using contralateral osteochondral humeral autograft and hemiarthroplasty. We report our experiences and clinical outcomes in managing four such cases using a variety and combination of treatments, including the first reported use of reverse shoulder arthroplasty with contralateral osteochondral humeral autografting. Results Shoulders reconstructed with humeral autograft demonstrated superior Oxford Shoulder Scores and an improved range of motion, as measured by a markerless machine vision system, compared to hemiarthroplasty. Conclusions Our results support the use of a contralateral humeral autograft in bilateral posterior shoulder fracture dislocation.

  2. 40 CFR Appendix D to Part 75 - Optional SO2 Emissions Data Protocol for Gas-Fired and Oil-Fired Peaking Units

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 16 2011-07-01 2011-07-01 false Optional SO2 Emissions Data Protocol for Gas-Fired and Oil-Fired Peaking Units D Appendix D to Part 75 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTINUOUS EMISSION MONITORING Pt. 75, App. D Appendix D to Part 75—Optional SO2...

  3. 40 CFR Appendix D to Part 75 - Optional SO2 Emissions Data Protocol for Gas-Fired and Oil-Fired Units

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false Optional SO2 Emissions Data Protocol for Gas-Fired and Oil-Fired Units D Appendix D to Part 75 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTINUOUS EMISSION MONITORING Pt. 75, App. D Appendix D to Part 75—Optional SO2 Emissions...

  4. A decision methodology for the evaluation of mixed low-level radioactive waste management options for DOE sites

    SciTech Connect

    Bassi, J.; Abashian, M.S.; Chakraborti, S.; Devarakonda, M.; Djordjevic, S.M.

    1993-03-01

    Currently, many DOE sites are developing site-specific solutions to manage their mixed low-level wastes. These site-specific MLLW programs often result in duplication of efforts between the different sites, and consequently, inefficient use of DOE system resources. A nationally integrated program for MLLW eliminates unnecessary duplication of effort, but requires a comprehensive analysis of waste management options to ensure that all site issues are addressed. A methodology for comprehensive analysis of the complete DOE MLLW system is being developed by DOE-HQ to establish an integrated and standardized solution for managing MLLW. To be effective, the comprehensive systems analysis must consider all aspects of MLLW management from cradle-to-grave (i.e. from MLLW generation to disposal). The results of the analysis will include recommendations for alternative management options for the complete DOE MLLW system based on various components such as effectiveness, cost, health and safety risks, and the probability of regulatory acceptance for an option. Because of the diverse nature of these various components and the associated difficulties in comparing between them, a decision methodology is being developed that will integrate the above components into a single evaluation scheme for performing relative comparisons between different MLLW management options. The remainder of this paper provides an overview of the roles and responsibilities of the various participants of the DOE MLLW Program, and discusses in detail the components involved in the development of the decision methodology for a comprehensive systems analysis.

  5. The RealGas and RealGasH2O options of the TOUGH+ code for the simulation of coupled fluid and heat flow in tight/shale gas systems

    NASA Astrophysics Data System (ADS)

    Moridis, George J.; Freeman, Craig M.

    2014-04-01

    We developed two new EOS additions to the TOUGH+ family of codes, the RealGasH2O and RealGas. The RealGasH2O EOS option describes the non-isothermal two-phase flow of water and a real gas mixture in gas reservoirs, with a particular focus in ultra-tight (such as tight-sand and shale gas) reservoirs. The gas mixture is treated as either a single-pseudo-component having a fixed composition, or as a multicomponent system composed of up to 9 individual real gases. The RealGas option has the same general capabilities, but does not include water, thus describing a single-phase, dry-gas system. In addition to the standard capabilities of all members of the TOUGH+ family of codes (fully-implicit, compositional simulators using both structured and unstructured grids), the capabilities of the two codes include coupled flow and thermal effects in porous and/or fractured media, real gas behavior, inertial (Klinkenberg) effects, full micro-flow treatment, Darcy and non-Darcy flow through the matrix and fractures of fractured media, single- and multi-component gas sorption onto the grains of the porous media following several isotherm options, discrete and fracture representation, complex matrix-fracture relationships, and porosity-permeability dependence on pressure changes. The two options allow the study of flow and transport of fluids and heat over a wide range of time frames and spatial scales not only in gas reservoirs, but also in problems of geologic storage of greenhouse gas mixtures, and of geothermal reservoirs with multi-component condensable (H2O and CH4) and non-condensable gas mixtures. The codes are verified against available analytical and semi-analytical solutions. Their capabilities are demonstrated in a series of problems of increasing complexity, ranging from isothermal flow in simpler 1D and 2D conventional gas reservoirs, to non-isothermal gas flow in 3D fractured shale gas reservoirs involving 4 types of fractures, micro-flow, non-Darcy flow and gas

  6. The RealGas and RealGasH2O Options of the TOUGH+ Code for the Simulation of Coupled Fluid and Heat Flow in Tight/Shale Gas Systems

    SciTech Connect

    Moridis, George; Freeman, Craig

    2013-09-30

    We developed two new EOS additions to the TOUGH+ family of codes, the RealGasH2O and RealGas . The RealGasH2O EOS option describes the non-isothermal two-phase flow of water and a real gas mixture in gas reservoirs, with a particular focus in ultra-tight (such as tight-sand and shale gas) reservoirs. The gas mixture is treated as either a single-pseudo-component having a fixed composition, or as a multicomponent system composed of up to 9 individual real gases. The RealGas option has the same general capabilities, but does not include water, thus describing a single-phase, dry-gas system. In addition to the standard capabilities of all members of the TOUGH+ family of codes (fully-implicit, compositional simulators using both structured and unstructured grids), the capabilities of the two codes include: coupled flow and thermal effects in porous and/or fractured media, real gas behavior, inertial (Klinkenberg) effects, full micro-flow treatment, Darcy and non-Darcy flow through the matrix and fractures of fractured media, single- and multi-component gas sorption onto the grains of the porous media following several isotherm options, discrete and fracture representation, complex matrix-fracture relationships, and porosity-permeability dependence on pressure changes. The two options allow the study of flow and transport of fluids and heat over a wide range of time frames and spatial scales not only in gas reservoirs, but also in problems of geologic storage of greenhouse gas mixtures, and of geothermal reservoirs with multi-component condensable (H2O and CH4) and non-condensable gas mixtures. The codes are verified against available analytical and semi-analytical solutions. Their capabilities are demonstrated in a series of problems of increasing complexity, ranging from isothermal flow in simpler 1D and 2D conventional gas reservoirs, to non-isothermal gas flow in 3D fractured shale gas reservoirs involving 4 types of fractures, micro-flow, non-Darcy flow and gas

  7. Underground natural gas storage reservoir management

    SciTech Connect

    Ortiz, I.; Anthony, R.

    1995-06-01

    The objective of this study is to research technologies and methodologies that will reduce the costs associated with the operation and maintenance of underground natural gas storage. This effort will include a survey of public information to determine the amount of natural gas lost from underground storage fields, determine the causes of this lost gas, and develop strategies and remedial designs to reduce or stop the gas loss from selected fields. Phase I includes a detailed survey of US natural gas storage reservoirs to determine the actual amount of natural gas annually lost from underground storage fields. These reservoirs will be ranked, the resultant will include the amount of gas and revenue annually lost. The results will be analyzed in conjunction with the type (geologic) of storage reservoirs to determine the significance and impact of the gas loss. A report of the work accomplished will be prepared. The report will include: (1) a summary list by geologic type of US gas storage reservoirs and their annual underground gas storage losses in ft{sup 3}; (2) a rank by geologic classifications as to the amount of gas lost and the resultant lost revenue; and (3) show the level of significance and impact of the losses by geologic type. Concurrently, the amount of storage activity has increased in conjunction with the net increase of natural gas imports as shown on Figure No. 3. Storage is playing an ever increasing importance in supplying the domestic energy requirements.

  8. Axillary radiotherapy: an alternative treatment option for adjuvant axillary management of breast cancer

    PubMed Central

    Zhang, Jie; Wang, Chuan

    2016-01-01

    Axillary lymph node dissection is standard management of axilla in invasive breast cancer. Radiotherapy also is important in local treatment. It is controversial as to whether axillary radiotherapy can displace axillary lymph node dissection. We performed a meta-analysis comparing axillary radiotherapy with axillary dissection. No significant difference was observed for disease free survival and overall survival between the radiation group and the dissection group. There was also no significant difference in either the axillary recurrence or the local recurrence between the two groups. But the axillary relapse rate in the radiation group was higher than in the surgery group at five-year follow-up while the local recurrence rate in the surgery group was higher than in the radiation group. A subgroup analysis showed that the difference in the axillary recurrence rate (RR = 0.20, P = 0.01) and local recurrence rate (RR = 4.7, P = 0.01) mainly appeared in the clinical node-positive subgroup. The edema rate in the surgery group was higher than in the radiation group (RR = 2.08, 95%: 1.71–2.54, P < 0.0001). We concluded that radiotherapy may be an alternative treatment option for adjuvant management of the axilla in selected sub-groups of patients. PMID:27212421

  9. Preeclampsia – Aetiology, Current Diagnostics and Clinical Management, New Therapy Options and Future Perspectives

    PubMed Central

    Tallarek, A.-C.; Huppertz, B.; Stepan, H.

    2012-01-01

    Preeclampsia is a multisystem disease for which the exact causes have not yet been sufficiently clarified. However, in the past few years it has become clear that a placental imbalance between angiogenic and anti-angiogenic proteins is the decisive pathogenetic factor for the occurrence of preeclampsia. With the possibility to measure these angiogenic factors (sFlt-1/PlGF ratio) in maternal blood full new diagnostic possibilities have been opened that enable the certain diagnosis or exclusion of the diseases as well as a short-term prognosis to be made. In secondary prevention the current data situation for ASA confirms a moderate but measurable utility. The management concept depends on gestational age. In the case of early clinical manifestations (< 34th week of pregnancy) the clinical management in a perinatal centre remains unchanged with foeto-maternal monitoring and induction of pulmonary maturation, symptomatic therapy under careful blood pressure lowering and determination of the optimal delivery time. A balance must be made here between foetal immaturity and maternal risks upon prolongations. The pathomechanism of anti-angiogenic overload with sFlt-1 provides a starting point for first therapeutic interventions. The present article gives an overview of current diagnostic options and presents possible future therapeutic perspectives for discussion. PMID:26640284

  10. Assessing management options to reduce water temperatures in regulated rivers of California

    NASA Astrophysics Data System (ADS)

    Pike, A.; Danner, E.; Boughton, D. A.; Harrison, L.

    2014-12-01

    In many regulated rivers throughout the western United States, deliberate management of water temperature below reservoirs is crucial to the survival of endangered salmonids. However, management options at reservoirs are often limited to adjusting either the flow volume and/or release temperature to alter the downstream water temperature. Here we investigate the efficacy of this approach in three major regulated rivers in California: the Sacramento River, the Klamath River, and the St. Ynez River. We use a 1-dimensional water temperature model (RAFT) to compute heat fluxes to/from the river based on meteorological conditions, channel bathymetry, and reservoir releases. A sensitivity analysis evaluates the thermal response of the river to reservoir releases during summertime flow conditions. Results indicate that the water temperature dynamics downstream of reservoirs vary between rivers. Although both the Sacramento and Klamath Rivers exhibit cooling in response to increased flows, the Sacramento River is cooled more effectively by decreasing the release temperature. In contrast, increased flow rate in the St. Ynez River does not as strongly influence downstream temperatures due to shallower flows combined with significant thermal buffering already provided by deep alluvial streambed.

  11. Managing gas plant margins through the financial commodities market

    SciTech Connect

    Peters, D.; Lafferty, L.

    1995-12-31

    Gas processors invest capital in gas plants to condition raw natural gas for market. They also attempt to upgrade the value of natural gas streams by removing gas liquids contained in these streams and selling them for a profit. Unfortunately, this is not always possible. Gas processing profit margins swing up and down in line with the volatility of the natural gas and gas liquids markets. Consequently the return on gas processors invested capital also swings up and down through ``good years`` and ``bad years``. Until recently, gas processors have had to bear the risk associated with these swings in margins. While an efficient market exists for products like crude oil on the New York Mercantile Exchange, no similar market has been available for gas liquids. The NYMEX propane contract has not developed sufficient liquidity for year round hedging of propane, much less the other gas liquids. Processors in regions without access to the Belvieu market encounter an even more difficult task attempting to use the NYMEX contract to hedge. Today this inability to manage risk is beginning to change. The natural gas markets have led the way since their deregulation with an actively traded over-the-counter forwards market firmly established. An over-the-counter forwards market for gas liquids has also started to emerge. It is through these new and emerging markets that a gas plant`s profitability can be hedged.

  12. Managing gas plant margins through the financial commodities markets

    SciTech Connect

    Peters, D.; Lafferty, L.

    1995-11-01

    Gas processors invest capital in gas plants to condition raw natural gas for market. They also attempt to upgrade the value of natural gas stream by removing gas liquids contained in these streams and selling them for a profit. Unfortunately, this is not always possible. Gas processing profit margins swing up and down in the line with the volatility of the natural gas and gas liquids markets. Consequently the return on gas processors invested capital also swings up and down through ``good years`` and ``bad years.`` Until recently, gas processors have had to bear the risk associated with these swings in margins. While an efficient market exists for products like crude oil on the New York Mercantile Exchange, no similar market has been available for gas liquids. The NYMEX propane contract has not developed sufficient liquidity for year round hedging of propane, much less the other gas liquids. Processors in regions without access to the Belvieu market encounter an even more difficult task attempting to use the NYMEX contract to hedge. Today this inability to manage risk is beginning to change. The natural gas markets have led the way since their deregulation with an actively traded over-the-counter forwards market firmly established. An over-the-encounter forward market for gas liquids has also started to emerge. It is through these new and emerging markets that a gas plant`s profitability can be hedged.

  13. Use of population viability analysis to evaluate CITES trade-management options for threatened marine fishes.

    PubMed

    Curtis, Janelle M R; Vincent, Amanda C J

    2008-10-01

    Achieving multiple conservation objectives can be challenging, particularly under high uncertainty. Having agreed to limit seahorse (Hippocampus) exports to sustainable levels, signatories to the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) were offered the option of a single 10-cm minimum size limit (MSL) as an interim management measure for all Hippocampus species (> or =34). Although diverse stakeholders supported the recommended MSL, its biological and socioeconomic implications were not assessed quantitatively. We combined population viability analysis, model sensitivity analysis, and economic information to evaluate the trade-off between conservation threat to and long-term cumulative income from these exploited marine fishes of high conservation concern. We used the European long-snouted seahorse (Hippocampus guttulatus) as a representative species to compare the performance of MSLs set at alternative biological reference points. Our sensitivity analyses showed that in most of our scenarios, setting the MSL just above size at maturity (9.7 cm in H. guttulatus) would not prevent exploited populations from becoming listed as vulnerable. By contrast, the relative risk of decline and extinction were almost halved--at a cost of only a 5.6% reduction in long-term catches--by increasing the MSL to the size reached after at least one full reproductive season. On the basis of our analysis, a precautionary increase in the MSL could be compatible with sustaining fishers' livelihoods and international trade. Such management tactics that aid species conservation and have minimal effects on long term catch trends may help bolster the case for CITES trade management of other valuable marine fishes. PMID:18680503

  14. Sustainability and energy development: influences of greenhouse gas emission reduction options on water use in energy production.

    PubMed

    Cooper, D Craig; Sehlke, Gerald

    2012-03-20

    Climate change mitigation strategies cannot be evaluated solely in terms of energy cost and greenhouse gas (GHG) mitigation potential. Maintaining GHGs at a "safe" level will require fundamental change in the way we approach energy production, and a number of environmental, economic, and societal factors will come into play. Water is an essential component of energy production, and water resource constraints will limit our options for meeting society's growing demand for energy while also reducing GHG emissions. This study evaluates these potential constraints from a global perspective by revisiting the climate wedges proposal of Pacala and Socolow (Science2004, 305 (5686), 968-972) and evaluating the potential water-use impacts of the wedges associated with energy production. GHG mitigation options that improve energy conversion or use efficiency can simultaneously reduce GHG emissions, lower energy costs, and reduce energy impacts on water resources. Other GHG mitigation options (e.g., carbon capture and sequestration, traditional nuclear, and biofuels from dedicated energy crops) increase water requirements for energy. Achieving energy sustainability requires deployment of alternatives that can reduce GHG emissions, water resource impacts, and energy costs. PMID:22283709

  15. The Management Options of Water for the Development of Agriculture in Dry Areas

    NASA Astrophysics Data System (ADS)

    Irshad, M.; Inoue, M.; Ashraf, M.; Al-Busaidi, A.

    . Without action, it has been reported that in 2025, two thirds of the world=s population would live in water stressed areas. One of the actions necessary to help avert water crisis is to educate people as to the value of this precious resource. A productive water-use system in arid and semiarid areas, where the annual rainfall is scanty, the evaporation rate is higher than precipitation and characterizes insufficient renewable water resources, is the urgent need of the farmers. This study reviews options available for improved utilization and management of water resources and examines the future prospects of sustainable agriculture in water scarce areas.

  16. 40 CFR Appendix D to Part 75 - Optional SO2 Emissions Data Protocol for Gas-Fired and Oil-Fired Units

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... for Gas-Fired and Oil-Fired Units D Appendix D to Part 75 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTINUOUS EMISSION MONITORING Pt. 75, App. D Appendix D to Part 75—Optional SO2 Emissions Data Protocol for Gas-Fired and Oil-Fired Units 1....

  17. Measuring and managing reservoir greenhouse gas emissions

    EPA Science Inventory

    Methane (CH4) is the second most important anthropogenic greenhouse gas with a heat trapping capacity 34 times greater than that of carbon dioxide on a 100 year time scale. Known anthropogenic CH4 sources include livestock production, rice agriculture, landfills, and natural gas...

  18. Changing Climate, Challenging Choices: Identifying and Evaluating Climate Change Adaptation Options for Protected Areas Management in Ontario, Canada

    NASA Astrophysics Data System (ADS)

    Lemieux, Christopher J.; Scott, Daniel J.

    2011-10-01

    Climate change will pose increasingly significant challenges to managers of parks and other forms of protected areas around the world. Over the past two decades, numerous scientific publications have identified potential adaptations, but their suitability from legal, policy, financial, internal capacity, and other management perspectives has not been evaluated for any protected area agency or organization. In this study, a panel of protected area experts applied a Policy Delphi methodology to identify and evaluate climate change adaptation options across the primary management areas of a protected area agency in Canada. The panel identified and evaluated one hundred and sixty five (165) adaptation options for their perceived desirability and feasibility. While the results revealed a high level of agreement with respect to the desirability of adaptation options and a moderate level of capacity pertaining to policy formulation and management direction, a perception of low capacity for implementation in most other program areas was identified. A separate panel of senior park agency decision-makers used a multiple criterion decision-facilitation matrix to further evaluate the institutional feasibility of the 56 most desirable adaptation options identified by the initial expert panel and to prioritize them for consideration in a climate change action plan. Critically, only two of the 56 adaptation options evaluated by senior decision-makers were deemed definitely implementable, due largely to fiscal and internal capacity limitations. These challenges are common to protected area agencies in developed countries and pervade those in developing countries, revealing that limited adaptive capacity represents a substantive barrier to biodiversity conservation and other protected area management objectives in an era of rapid climate change.

  19. Hydrological services and biodiversity conservation under forestation scenarios: comparing options to improve watershed management

    NASA Astrophysics Data System (ADS)

    Carvalho-Santos, Claudia; Nunes, João Pedro; Sousa-Silva, Rita; Gonçalves, João; Pradinho Honrado, João

    2015-04-01

    Humans rely on ecosystems for the provision of hydrological services, namely water supply and water damage mitigation, and promoting forests is a widely used management strategy for the provision of hydrological services. Therefore, it is important to model how forests will contribute for this provision, taking into account the environmental characteristics of each region, as well as the spatio-temporal patterns of societal demand. In addition, ensuring forest protection and the delivery of forest ecosystem services is one of the aims included in the European Union biodiversity strategy to 2020. On the other hand, forest management for hydrological services must consider possible trade-offs with other services provision, as well as with biodiversity conservation. Accurate modeling and mapping of both hydrological services and biodiversity conservation value is thus important to support spatial planning and land management options involving forests. The objectives of this study were: to analyze the provision and spatial dynamics of hydrological services under two forest cover change scenarios (oak and eucalyptus/pine) compared to the current shrubland-dominated landscape; and to evaluate their spatial trade-offs with biodiversity conservation value. The Vez watershed (250km2), in northwest Portugal, was used as case-study area. SWAT (Soil and Water Assessment Tool) was applied to simulate the provision of hydrological services (water supply quantity, timing and quality; soil erosion and flood regulation), and was calibrated against daily discharge, sediments, nitrates and evapotranspiration. Good agreement was obtained between model predictions and field measurements. The maps for each service under the different scenarios were produced at the Hydrologic Response Unit (HRU) level. Biodiversity conservation value was based on nature protection regimes and on expert valuation applied to a land cover map. Statistical correlations between hydrological services provision

  20. Acute vasculitis resulting in free flap failure: the importance of early recognition and options for management.

    PubMed

    Brennan, P A; Colbert, S; Spedding, A V; Herd, M K; Mellor, T K; Anand, R; McCrae, F

    2012-11-01

    Unusual or unexpected medical causes for free flap failure do occur but are uncommon. We present a rare case of a fibula free flap failure due to an acute vasculitis which was undiagnosed until after the flap had failed. In addition to two successful flap salvages and intravenous heparin, an epoprostenol infusion was commenced but a third salvage was not successful. The vasculitis resulted in marked blood vessel wall thickening, and cutaneous manifestations which presented as late signs. High peri-nuclear anti nuclear cytoplasmic antibody (pANCA) and myeloperoxidase (MOP) titres were subsequently found and histology from several blood vessels showed marked inflammation throughout the wall. A diagnosis of microscopic polyangiitis was made and high dose steroids were subsequently commenced. Interestingly, he had vasculitis several years previously treated with oral steroids but had been discharged from the rheumatology clinic. This rare case illustrates the potential hazards of free flap surgery in the vasculitides and discusses the warning signs and various management options to reduce the likelihood of flap failure in these patients. PMID:22534125

  1. Bariatric to metabolic surgery: management options and experience at a tertiary centre.

    PubMed

    Raj, P Praveen; Chandramaliteeswaran, C; Senthilnathan, P; Asokan, S; Palanivelu, C

    2010-10-01

    Obesity proves to be a growing pandemic with severe health and economic implications. Bariatric surgeries are now recognised as metabolic surgeries given the excellent resolution of metabolic derangements accompanying obesity. This concept of metabolic surgery is now applied to non-obese population with metabolic disorders. The type II diabetes mellitus remission rates as high as 95% have been reported, least with restrictive procedures and maximum with malabsorptive procedures and such effect occurs even before substantial weight loss. This has led to increased understanding of diabetes pathophysiology and formulation of foregut and hindgut hypothesis. The aim of this study was to briefly review the management options for morbid obesity and present the results at a high volume centre. Data from 518 patients who underwent laparoscopic bariatric surgeries at this institute since 2002 were taken up for analysis retrospectively. Study population included 518 patients with 310 males and 208 females. Excess body weight loss and comorbidity resolution rates were analysed. Laparoscopic bariatric surgery is safe and effective for excess body weight loss and confers excellent resolution of associated comorbidities. PMID:21510546

  2. Toward a protocol for quantifying the greenhouse gas balance and identifying mitigation options in smallholder farming systems

    NASA Astrophysics Data System (ADS)

    Rosenstock, T. S.; Rufino, M. C.; Butterbach-Bahl, K.; Wollenberg, E.

    2013-06-01

    Globally, agriculture is directly responsible for 14% of annual greenhouse gas (GHG) emissions and induces an additional 17% through land use change, mostly in developing countries (Vermeulen et al 2012). Agricultural intensification and expansion in these regions is expected to catalyze the most significant relative increases in agricultural GHG emissions over the next decade (Smith et al 2008, Tilman et al 2011). Farms in the developing countries of sub-Saharan Africa and Asia are predominately managed by smallholders, with 80% of land holdings smaller than ten hectares (FAO 2012). One can therefore posit that smallholder farming significantly impacts the GHG balance of these regions today and will continue to do so in the near future. However, our understanding of the effect smallholder farming has on the Earth's climate system is remarkably limited. Data quantifying existing and reduced GHG emissions and removals of smallholder production systems are available for only a handful of crops, livestock, and agroecosystems (Herrero et al 2008, Verchot et al 2008, Palm et al 2010). For example, fewer than fifteen studies of nitrous oxide emissions from soils have taken place in sub-Saharan Africa, leaving the rate of emissions virtually undocumented. Due to a scarcity of data on GHG sources and sinks, most developing countries currently quantify agricultural emissions and reductions using IPCC Tier 1 emissions factors. However, current Tier 1 emissions factors are either calibrated to data primarily derived from developed countries, where agricultural production conditions are dissimilar to that in which the majority of smallholders operate, or from data that are sparse or of mixed quality in developing countries (IPCC 2006). For the most part, there are insufficient emissions data characterizing smallholder agriculture to evaluate the level of accuracy or inaccuracy of current emissions estimates. Consequentially, there is no reliable information on the agricultural

  3. Poor response to clopidogrel: current and future options for its management.

    PubMed

    Campo, Gianluca; Fileti, Luca; Valgimigli, Marco; Tebaldi, Matteo; Cangiano, Elisa; Cavazza, Caterina; Marchesini, Jlenia; Ferrari, Roberto

    2010-10-01

    Antiplatelet therapy is the cornerstone of treatment for patients with acute coronary syndromes and/or undergoing percutaneous coronary interventions (PCI). Clopidogrel, a thienopyridine antiplatelet agent, has been used to prevent vascular complication in atherothrombotic patients, to prevent stent thrombosis in patients undergoing PCI, and in long term prevention of cardiovascular and cerebrovascular events. More than 40 million patients in the world receive clopidogrel but unfortunately about 20% of these are either non or poor responders. Several methods have been used to assess clopidogrel-induced antiplatelet effects. However, none of these tests have been fully standardized or fully agreed upon to measure clopidogrel responsiveness. Nevertheless, many studies using different techniques, platelet agonists and definitions, showed that patients with a poor response to clopidogrel have an increased risk of death, reinfarction and stent thrombosis. The mechanisms leading to poor responsiveness are not fully clarified and are likely multifactorial: genetic factors, accelerated platelet turnover, up-regulation of the P2Y(12) pathways, high baseline platelet reactivity, poor compliance, under-dosing and drug-drug interactions. The management of these patients is very difficult, but some evidence showed that a strategy of higher maintenance dose or switch to different thienopyridine (e.g. ticlopidine or prasugrel) or use of glycoprotein IIb/IIIa inhibitors during PCI may be helpful to overcome poor responsiveness and improve the long-term clinical outcome. This paper reviews the impact of clopidogrel poor responsiveness on clinical outcomes, the mechanisms leading to poor effect and the different assays to assess it. Finally, current and future options for its management is discussed. PMID:20157839

  4. Reactor-based management of used nuclear fuel: assessment of major options.

    PubMed

    Finck, Phillip J; Wigeland, Roald A; Hill, Robert N

    2011-01-01

    This paper discusses the current status of the ongoing Advanced Fuel Cycle Initiative (AFCI) program in the U.S. Department of Energy that is investigating the potential for using the processing and recycling of used nuclear fuel to improve radioactive waste management, including used fuel. A key element of the strategies is to use nuclear reactors for further irradiation of recovered chemical elements to transmute certain long-lived highly-radioactive isotopes into less hazardous isotopes. Both thermal and fast neutron spectrum reactors are being studied as part of integrated nuclear energy systems where separations, transmutation, and disposal are considered. Radiotoxicity is being used as one of the metrics for estimating the hazard of used fuel and the processing of wastes resulting from separations and recycle-fuel fabrication. Decay heat from the used fuel and/or wastes destined for disposal is used as a metric for use of a geologic repository. Results to date indicate that the most promising options appear to be those using fast reactors in a repeated recycle mode to limit buildup of higher actinides, since the transuranic elements are a key contributor to the radiotoxicity and decay heat. Using such an approach, there could be much lower environmental impact from the high-level waste as compared to direct disposal of the used fuel, but there would likely be greater generation of low-level wastes that will also require disposal. An additional potential waste management benefit is having the ability to tailor waste forms and contents to one or more targeted disposal environments (i.e., to be able to put waste in environments best-suited for the waste contents and forms). PMID:21399411

  5. Subsurface Hybrid Power Options for Oil & Gas Production at Deep Ocean Sites

    SciTech Connect

    Farmer, J C; Haut, R; Jahn, G; Goldman, J; Colvin, J; Karpinski, A; Dobley, A; Halfinger, J; Nagley, S; Wolf, K; Shapiro, A; Doucette, P; Hansen, P; Oke, A; Compton, D; Cobb, M; Kopps, R; Chitwood, J; Spence, W; Remacle, P; Noel, C; Vicic, J; Dee, R

    2010-02-19

    An investment in deep-sea (deep-ocean) hybrid power systems may enable certain off-shore oil and gas exploration and production. Advanced deep-ocean drilling and production operations, locally powered, may provide commercial access to oil and gas reserves otherwise inaccessible. Further, subsea generation of electrical power has the potential of featuring a low carbon output resulting in improved environmental conditions. Such technology therefore, enhances the energy security of the United States in a green and environmentally friendly manner. The objective of this study is to evaluate alternatives and recommend equipment to develop into hybrid energy conversion and storage systems for deep ocean operations. Such power systems will be located on the ocean floor and will be used to power offshore oil and gas exploration and production operations. Such power systems will be located on the oceans floor, and will be used to supply oil and gas exploration activities, as well as drilling operations required to harvest petroleum reserves. The following conceptual hybrid systems have been identified as candidates for powering sub-surface oil and gas production operations: (1) PWR = Pressurized-Water Nuclear Reactor + Lead-Acid Battery; (2) FC1 = Line for Surface O{sub 2} + Well Head Gas + Reformer + PEMFC + Lead-Acid & Li-Ion Batteries; (3) FC2 = Stored O2 + Well Head Gas + Reformer + Fuel Cell + Lead-Acid & Li-Ion Batteries; (4) SV1 = Submersible Vehicle + Stored O{sub 2} + Fuel Cell + Lead-Acid & Li-Ion Batteries; (5) SV2 = Submersible Vehicle + Stored O{sub 2} + Engine or Turbine + Lead-Acid & Li-Ion Batteries; (6) SV3 = Submersible Vehicle + Charge at Docking Station + ZEBRA & Li-Ion Batteries; (7) PWR TEG = PWR + Thermoelectric Generator + Lead-Acid Battery; (8) WELL TEG = Thermoelectric Generator + Well Head Waste Heat + Lead-Acid Battery; (9) GRID = Ocean Floor Electrical Grid + Lead-Acid Battery; and (10) DOC = Deep Ocean Current + Lead-Acid Battery.

  6. Federal and Indian oil and gas royalty valuation and management

    SciTech Connect

    Not Available

    1992-01-01

    This book covers: Royalty management-an M.M.S. overview; Payor/operator/lessee royalty liability; Royalty issues for OCS lessees; Royalty valuation procedures; Gas marketing royalty issues - industry perspective; Gas marketing royalty issues - M.M.S. perspective; Settlements of gas contract disputes Royalty reporting issues; Production reporting issues; Indian royalty issues; Litigation/regulatory updates; Over/under production on federal leases, units, and communitized areas; Audit program; and M.M.S. Reference Handbook.

  7. Miscellaneous: Uruguay energy supply options study assessing the market for natural gas - executive summary.

    SciTech Connect

    Conzelmann, G.; Veselka, T.; Decision and Information Sciences

    2008-03-04

    Uruguay is in the midst of making critical decisions affecting the design of its future energy supply system. Momentum for change is expected to come from several directions, including recent and foreseeable upgrades and modifications to energy conversion facilities, the importation of natural gas from Argentina, the possibility for a stronger interconnection of regional electricity systems, the country's membership in MERCOSUR, and the potential for energy sector reforms by the Government of Uruguay. The objective of this study is to analyze the effects of several fuel diversification strategies on Uruguay's energy supply system. The analysis pays special attention to fuel substitution trends due to potential imports of natural gas via a gas pipeline from Argentina and increasing electricity ties with neighboring countries. The Government of Uruguay has contracted with Argonne National Laboratory (ANL) to study several energy development scenarios with the support of several Uruguayan institutions. Specifically, ANL was asked to conduct a detailed energy supply and demand analysis, develop energy demand projections based on an analysis of past energy demand patterns with support from local institutions, evaluate the effects of potential natural gas imports and electricity exchanges, and determine the market penetration of natural gas under various scenarios.

  8. A Study on Optimized Management Options for the Wolsong Low- and Intermediate - Level Waste Disposal Center in Korea - 13479

    SciTech Connect

    Park, JooWan; Kim, DongSun; Choi, DongEun

    2013-07-01

    The safe and effective management of radioactive waste is a national task required for sustainable generation of nuclear power and for energy self-reliance in Korea. Currently, for permanent disposal of low- and intermediate-level waste (LILW), the Wolsong LILW Disposal Center (WLDC) is under construction. It will accommodate a total of 800,000 drums at the final stage after stepwise expansion. As an implementing strategy for cost-effective development of the WLDC, various disposal options suitable for waste classification schemes would be considered. It is also needed an optimized management of the WLDC by taking a countermeasure of volume reduction treatment. In this study, various management options to be applied to each waste class are analyzed in terms of its inventory and disposal cost. For the volume reduction and stabilization of waste, the vitrification and plasma melting methods are considered for combustible and incombustible waste, respectively. (authors)

  9. Greenhouse gas emission mitigation relevant to changes in municipal solid waste management system.

    PubMed

    Pikoń, Krzysztof; Gaska, Krzysztof

    2010-07-01

    Standard methods for assessing the environmental impact of waste management systems are needed to underpin the development and implementation of sustainable waste management practice. Life cycle assessment (LCA) is a tool for comprehensively ensuring such assessment and covers all impacts associated with waste management. LCA is often called "from cradle to grave" analysis. This paper integrates information on the greenhouse gas (GHG) implications of various management options for some of the most common materials in municipal solid waste (MSW). Different waste treatment options for MSW were studied in a system analysis. Different combinations of recycling (cardboard, plastics, glass, metals), biological treatment (composting), and incineration as well as land-filling were studied. The index of environmental burden in the global warming impact category was calculated. The calculations are based on LCA methodology. All emissions taking place in the whole life cycle system were taken into account. The analysis included "own emissions," or emissions from the system at all stages of the life cycle, and "linked emissions," or emissions from other sources linked with the system in an indirect way. Avoided emissions caused by recycling and energy recovery were included in the analysis. Displaced emissions of GHGs originate from the substitution of energy or materials derived from waste for alternative sources. The complex analysis of the environmental impact of municipal waste management systems before and after application of changes in MSW systems according to European Union regulations is presented in this paper. The evaluation is made for MSW systems in Poland. PMID:20681425

  10. A decision support tool to prioritize risk management options for contaminated sites.

    PubMed

    Sorvari, Jaana; Seppälä, Jyri

    2010-03-15

    The decisions on risk management (RM) of contaminated sites in Finland have typically been driven by practical factors such as time and money. However, RM is a multifaceted task that generally involves several additional determinants, e.g. performance and environmental effects of remediation methods, psychological and social factors. Therefore, we adopted a multi-criteria decision analysis approach and developed a decision support tool (DST) that is viable in decision-making in such a complex situation. The basic components of the DST are based on the Dutch REC system. However, our DST is more case-specific and allows the consideration of the type, magnitude and scale of contamination, land use, environmental conditions and socio-cultural aspects (e.g. loss of cultural heritage, image aspects). The construction of the DST was started by structuring the decision problem using a value tree. Based on this work we adopted the Multi-Attribute Value Theory (MAVT) for data aggregation. The final DST was demonstrated by two model sites for which the RM alternatives and site-specific data were created on the basis of factual remediation projects and by interviewing experts. The demonstration of the DST was carried out in a workshop where representatives of different stakeholders were requested to rank and weight the decision criteria involved. To get information on the consistency of the ranking of the RM alternatives, we used different weighting techniques (ratio estimation and pair-wise weighting) and alternative ways to treat individual respondents' weights in calculating the preference scores for each RM alternative. These dissimilar approaches resulted in some differences in the preference order of the RM alternatives. The demonstration showed that attention has to be paid to the proper description of the site, the principles of the procedure and the decision criteria. Nevertheless, the procedure proved to enable efficient communication between different stakeholders

  11. Update on marine omega-3 fatty acids: management of dyslipidemia and current omega-3 treatment options.

    PubMed

    Weintraub, Howard

    2013-10-01

    Low-density lipoprotein cholesterol (LDL-C) is currently the primary target in the management of dyslipidemia, and statins are first-line pharmacologic interventions. Adjunct therapy such as niacins, fibrates, bile acid sequestrants, or cholesterol absorption inhibitors may be considered to help reduce cardiovascular risk. This review discusses the need for alternative adjunct treatment options and the potential place for omega-3 fatty acids as such. The cardiovascular benefits of fish consumption are attributed to the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and a variety of omega-3 fatty acid products are available with varied amounts of EPA and DHA. The product types include prescription drugs, food supplements, and medical foods sourced from fish, krill, algal and plant oils or purified from these oils. Two prescription omega-3 fatty acids are currently available, omega-3 fatty acid ethyl esters (contains both EPA and DHA ethyl esters), and icosapent ethyl (IPE; contains high-purity EPA ethyl ester). A pharmaceutical containing free fatty acid forms of omega-3 is currently in development. Omega-3 fatty acid formulations containing EPA and DHA have been shown to increase LDL-C levels while IPE has been shown to lower triglyceride levels without raising LDL-C levels, alone or in combination with statin therapy. In addition, recent studies have not been able to demonstrate reduced cardiovascular risk following treatment with fibrates, niacins, cholesterol absorption inhibitors, or omega-3 fatty acid formulations containing both EPA and DHA in statin-treated patients; thus, there remains a need for further cardiovascular outcomes studies for adjunct therapy. PMID:24075771

  12. Production of Ceratonova shasta Myxospores from Salmon Carcasses: Carcass Removal Is Not a Viable Management Option.

    PubMed

    Foott, J S; Stone, R; Fogerty, R; True, K; Bolick, A; Bartholomew, J L; Hallett, S L; Buckles, G R; Alexander, J D

    2016-06-01

    ) and 2009 (1,799 carcasses removed) failed to measurably influence the DNA quantity of C. shasta in targeted waters. Combined with the high numbers of carcasses that contributed myxospores, we therefore deemed that this labor-intensive approach is not a viable management option to reduce the infectivity of C. shasta in Chinook Salmon in the Klamath River. Received January 23, 2015; accepted September 28, 2015. PMID:27064587

  13. ANALYSIS OF THE POTENTIAL EFFECTS OF TOXICS ON MUNICIPAL SOLID WASTE MANAGEMENT OPTIONS

    EPA Science Inventory

    Many alternative waste management practices and strategies are available to manage the large quantities of MSW generated every year. hese management alternatives include recycling, composting, waste-to-fuel/energy recovery, and landfilling. n choosing the best possible management...

  14. Marine management efforts for the Pagerungan gas development

    SciTech Connect

    Hamzah, A.; Saleh, A.A.; Budhi, T.S.

    1996-12-31

    ARCO and Pertamina in Indonesia have developed and are producing from gas reserves in the Pagerungan Field. The substantial commercial gas reserves of Pagerungan Field were discovered 1985. The gas producing facilities were built in 1991-1993 on Pagerungan and were designed for 350 MMSCFD of dry gas and 3,500 bbl/day of condensate. About 9 of the 16 planned wells are producing. The gas and condensate sales commenced on January 1994. In Pagerungan island, the aquatic marine environment plays an important role in sustaining organisms which in turn provide both employment and business opportunities for the local people. The Pagerungan gas development has been completed with a series of environmental studies. The studies point out that the development is likely to have a significant impact on the marine environment. For this reason, the company are responsible for managing and monitoring these possible effects and taking action to mitigate potential or actual problems.

  15. Characterization of options and their analysis requirements for the long-term management of depleted uranium hexafluoride

    SciTech Connect

    Dubrin, J.W.; Rosen, R.S.; Zoller, J.N.; Harri, J.W.; Schwertz, N.L.

    1995-12-01

    The Department of Energy (DOE) is examining alternative strategies for the long-term management of depleted uranium hexafluoride (UF{sub 6}) currently stored at the gaseous diffusion plants at Portsmouth, Ohio, and Paducah, Kentucky, and on the Oak Ridge Reservation in Oak Ridge, Tennessee. This paper describes the methodology for the comprehensive and ongoing technical analysis of the options being considered. An overview of these options, along with several of the suboptions being considered, is presented. The long-term management strategy alternatives fall into three broad categories: use, storage, or disposal. Conversion of the depleted UF6 to another form such as oxide or metal is needed to implement most of these alternatives. Likewise, transportation of materials is an integral part of constructing the complete pathway between the current storage condition and ultimate disposition. The analysis of options includes development of pre-conceptual designs; estimates of effluents, wastes, and emissions; specification of resource requirements; and preliminary hazards assessments. The results of this analysis will assist DOE in selecting a strategy by providing the engineering information necessary to evaluate the environmental impacts and costs of implementing the management strategy alternatives.

  16. A risk-based framework for water resource management under changing water availability, policy options, and irrigation expansion

    NASA Astrophysics Data System (ADS)

    Hassanzadeh, Elmira; Elshorbagy, Amin; Wheater, Howard; Gober, Patricia

    2016-08-01

    Long-term water resource management requires the capacity to evaluate alternative management options in the face of various sources of uncertainty in the future conditions of water resource systems. This study proposes a generic framework for determining the relative change in probabilistic characteristics of system performance as a result of changing water availability, policy options and irrigation expansion. These probabilistic characteristics can be considered to represent the risk of failure in the system performance due to the uncertainty in future conditions. Quantifying the relative change in the performance risk can provide a basis for understanding the effects of multiple changing conditions on the system behavior. This framework was applied to the water resource system of the Saskatchewan River Basin (SaskRB) in Saskatchewan, Canada. A "bottom-up" flow reconstruction algorithm was used to generate multiple realizations for water availability within a feasible range of change in streamflow characteristics. Consistent with observed data and projected change in streamflow characteristics, the historical streamflow was perturbed to stochastically generate feasible future flow sequences, based on various combinations of changing annual flow volume and timing of the annual peak. In addition, five alternative policy options, with and without potential irrigation expansion, were considered. All configurations of water availability, policy decisions and irrigation expansion options were fed into a hydro-economic water resource system model to obtain empirical probability distributions for system performance - here overall and sectorial net benefits - under the considered changes. Results show that no one specific policy can provide the optimal option for water resource management under all flow conditions. In addition, it was found that the joint impacts of changing water availability, policy, and irrigation expansion on system performance are complex and

  17. Offsite commercial disposal of oil and gas exploration and production waste :availability, options, and cost.

    SciTech Connect

    Puder, M. G.; Veil, J. A.

    2006-09-05

    A survey conducted in 1995 by the American Petroleum Institute (API) found that the U.S. exploration and production (E&P) segment of the oil and gas industry generated more than 149 million bbl of drilling wastes, almost 18 billion bbl of produced water, and 21 million bbl of associated wastes. The results of that survey, published in 2000, suggested that 3% of drilling wastes, less than 0.5% of produced water, and 15% of associated wastes are sent to offsite commercial facilities for disposal. Argonne National Laboratory (Argonne) collected information on commercial E&P waste disposal companies in different states in 1997. While the information is nearly a decade old, the report has proved useful. In 2005, Argonne began collecting current information to update and expand the data. This report describes the new 2005-2006 database and focuses on the availability of offsite commercial disposal companies, the prevailing disposal methods, and estimated disposal costs. The data were collected in two phases. In the first phase, state oil and gas regulatory officials in 31 states were contacted to determine whether their agency maintained a list of permitted commercial disposal companies dedicated to oil. In the second stage, individual commercial disposal companies were interviewed to determine disposal methods and costs. The availability of offsite commercial disposal companies and facilities falls into three categories. The states with high oil and gas production typically have a dedicated network of offsite commercial disposal companies and facilities in place. In other states, such an infrastructure does not exist and very often, commercial disposal companies focus on produced water services. About half of the states do not have any industry-specific offsite commercial disposal infrastructure. In those states, operators take their wastes to local municipal landfills if permitted or haul the wastes to other states. This report provides state-by-state summaries of the

  18. MELTER OFF-GAS FLAMMABILITY ASSESSMENT FOR DWPF ALTERNATE REDUCTANT FLOWSHEET OPTIONS

    SciTech Connect

    Choi, A.

    2011-07-08

    Glycolic acid and sugar are being considered as potential candidates to substitute for much of the formic acid currently being added to the Defense Waste Processing Facility (DWPF) melter feed as a reductant. A series of small-scale melter tests were conducted at the Vitreous State Laboratory (VSL) in January 2011 to collect necessary data for the assessment of the impact of these alternate reductants on the melter off-gas flammability. The DM10 melter with a 0.021 m{sup 2} melt surface area was run with three different feeds which were prepared at SRNL based on; (1) the baseline formic/nitric acid flowsheet, (2) glycolic/formic/nitric acid flowsheet, and (3) sugar/formic/nitric acid flowsheet - these feeds will be called the baseline, glycolic, and sugar flowsheet feeds, respectively, hereafter. The actual addition of sugar to the sugar flowsheet feed was made at VSL before it was fed to the melter. For each feed, the DM10 was run under both bubbled (with argon) and non-bubbled conditions at varying melter vapor space temperatures. The goal was to lower its vapor space temperature from nominal 500 C to less than 300 C at 50 C increments and maintain steady state at each temperature at least for one hour, preferentially for two hours, while collecting off-gas data including CO, CO{sub 2}, and H{sub 2} concentrations. Just a few hours into the first test with the baseline feed, it was discovered that the DM10 vapor space temperature would not readily fall below 350 C simply by ramping up the feed rate as the test plan called for. To overcome this, ambient air was introduced directly into the vapor space through a dilution air damper in addition to the natural air inleakage occurring at the operating melter pressure of -1 inch H{sub 2}O. A detailed description of the DM10 run along with all the data taken is given in the report issued by VSL. The SRNL personnel have analyzed the DM10 data and identified 25 steady state periods lasting from 32 to 92 minutes for all

  19. Management of a complex cavern storage facility for natural gas

    SciTech Connect

    1998-04-01

    The Epe cavern storage facility operated by Ruhrgas AG has developed into one of the largest gas cavern storage facilities in the world. Currently, there are 32 caverns and 18 more are planned in the future. Working gas volume will increase from approximately 1.5 {times} 10{sup 9} to 2 {times} 10{sup 9} m{sup 3}. The stratified salt deposit containing the caverns has a surface area of approximately 7 km{sup 2} and is 250 m thick at the edge and 400 m thick in the center. Caverns are leached by a company that uses the recovered brine in the chlorine industry. Cavern dimensions are determined before leaching. The behavior of each cavern, as well as the thermodynamic properties of natural gas must be considered in cavern management. The full-length paper presents the components of a complex management system covering the design, construction, and operation of the Epe gas-storage caverns.

  20. Phytoremediation of hydrocarbon contaminants in subantarctic soils: an effective management option.

    PubMed

    Bramley-Alves, Jessica; Wasley, Jane; King, Catherine K; Powell, Shane; Robinson, Sharon A

    2014-09-01

    Accidental fuel spills on world heritage subantarctic Macquarie Island have caused considerable contamination. Due to the island's high latitude position, its climate, and its fragile ecosystem, traditional methods of remediation are unsuitable for on-site clean up. We investigated the tolerance of a subantarctic native tussock grass, Poa foliosa (Hook. f.), to Special Antarctic Blend (SAB) diesel fuel and its potential to reduce SAB fuel contamination via phytoremediation. Toxicity of SAB fuel to P. foliosa was assessed in an 8 month laboratory growth trial under growth conditions which simulated the island's environment. Single seedlings were planted into 1 L pots of soil spiked with SAB fuel at concentrations of 1000, 5 000, 10,000, 2000 and 40,000 mg/kg (plus control). Plants were harvested at 0, 2, 4 and 8 months and a range of plant productivity endpoints were measured (biomass production, plant morphology and photosynthetic efficiency). Poa foliosa was highly tolerant across all SAB fuel concentrations tested with respect to biomass, although higher concentrations of 20,000 and 40,000 mg SAB/kg soil caused slight reductions in leaf length, width and area. To assess the phytoremediation potential of P. foliosa (to 10 000 mg/kg), soil from the planted pots was compared with that from paired unplanted pots at each SAB fuel concentration. The effect of the plant on SAB fuel concentrations and the associated microbial communities found within the soil (total heterotrophs and hydrocarbon degraders) were compared between planted and unplanted treatments at the 0, 2, 4 and 8 month harvest periods. The presence of plants resulted in significantly less SAB fuel in soils at 2 months and a return to background concentration by 8 months. Microbes did not appear to be the sole driving force behind the observed hydrocarbon loss. This study provides evidence that phytoremediation using P. foliosa is a valuable remediation option for use at Macquarie Island, and may be

  1. DRUMS: Disk Repository with Update Management and Select option for high throughput sequencing data

    PubMed Central

    2014-01-01

    Background New technologies for analyzing biological samples, like next generation sequencing, are producing a growing amount of data together with quality scores. Moreover, software tools (e.g., for mapping sequence reads), calculating transcription factor binding probabilities, estimating epigenetic modification enriched regions or determining single nucleotide polymorphism increase this amount of position-specific DNA-related data even further. Hence, requesting data becomes challenging and expensive and is often implemented using specialised hardware. In addition, picking specific data as fast as possible becomes increasingly important in many fields of science. The general problem of handling big data sets was addressed by developing specialized databases like HBase, HyperTable or Cassandra. However, these database solutions require also specialized or distributed hardware leading to expensive investments. To the best of our knowledge, there is no database capable of (i) storing billions of position-specific DNA-related records, (ii) performing fast and resource saving requests, and (iii) running on a single standard computer hardware. Results Here, we present DRUMS (Disk Repository with Update Management and Select option), satisfying demands (i)-(iii). It tackles the weaknesses of traditional databases while handling position-specific DNA-related data in an efficient manner. DRUMS is capable of storing up to billions of records. Moreover, it focuses on optimizing relating single lookups as range request, which are needed permanently for computations in bioinformatics. To validate the power of DRUMS, we compare it to the widely used MySQL database. The test setting considers two biological data sets. We use standard desktop hardware as test environment. Conclusions DRUMS outperforms MySQL in writing and reading records by a factor of two up to a factor of 10000. Furthermore, it can work with significantly larger data sets. Our work focuses on mid-sized data

  2. Using the Cancer Risk Management Model to evaluate colorectal cancer screening options for Canada

    PubMed Central

    Coldman, A.J.; Phillips, N.; Brisson, J.; Flanagan, W.; Wolfson, M.; Nadeau, C.; Fitzgerald, N.; Miller, A.B.

    2015-01-01

    Background Several screening methods for colorectal cancer (crc) are available, and some have been shown by randomized trials to be effective. In the present study, we used a well-developed population health simulation model to compare the risks and benefits of a variety of screening scenarios. Tests considered were the fecal occult blood test (fobt), the fecal immunochemical test (fit), flexible sigmoidoscopy, and colonoscopy. Outcomes considered included years of life gained, crc cases and deaths prevented, and direct health system costs. Methods A natural history model of crc was implemented and calibrated to specified targets within the framework of the Cancer Risk Management Model (crmm) from the Canadian Partnership Against Cancer. The crmm-crc permits users to enter their own parameter values or to use program-specified base values. For each of 23 screening scenarios, we used the crmm-crc to run 10 million replicate simulations. Results Using base parameter values and some user-specified values in the crmm-crc, and comparing our screening scenarios with no screening, all screening scenarios were found to reduce the incidence of and mortality from crc. The fobt was the least effective test; it was not associated with lower net cost. Colonoscopy screening was the most effective test; it had net costs comparable to those for several other strategies considered, but required more than 3 times the colonoscopy resources needed by other approaches. After colonoscopy, strategies based on the fit were predicted to be the most effective. In sensitivity analyses performed for the fobt and fit screening strategies, fobt parameter values associated with high-sensitivity formulations were associated with a substantial increase in test effectiveness. The fit was more cost-effective at the 50 ng/mL threshold than at the 100 ng/mL threshold. Conclusions The crmm-crc provides a sophisticated and flexible environment in which to evaluate crc control options. All screening

  3. Options for management of municipal solid waste in New York City: A preliminary comparison of health risks and policy implications

    PubMed Central

    Moy, Pearl; Krishnan, Nikhil; Ulloa, Priscilla; Cohen, Steven; Brandt-Rauf, Paul W.

    2008-01-01

    Landfill disposal and waste-to-energy (WTE) incineration remain the two principal options for managing municipal solid waste (MSW). One critical determinant of the acceptability of these options is the different health risks associated with each. In this analysis relying on published data and exposure modeling, we have performed health risk assessments for landfill disposal versus WTE treatment options for the management of New York City’s MSW. These are based on the realistic scenario of using a waste transfer station (WTS) in Brooklyn and then transporting the untreated MSW by truck to a landfill in Pennsylvania or using a WTE facility in Brooklyn and then transporting the resultant ash by truck to a landfill in Pennsylvania. The overall results indicate that the individual cancer risks for both options would be considered generally acceptable, although the risk from landfilling is approximately 5 times greater than from WTE treatment; the individual non-cancer health risks for both options would be considered generally unacceptable, although once again the risk from landfilling is approximately 5 times greater than from WTE treatment. If one considers only the population in Brooklyn that would be directly affected by the siting of either a WTS or a WTE facility in their immediate neighborhood, individual cancer and non-cancer health risks for both options would be considered generally acceptable, but risks for the former remain considerably higher than for the latter. These results should be considered preliminary due to several limitations of this study such as: consideration of risks only from inhalation exposures; assumption that only volume and not composition of the waste stream is altered by WTE treatment; reliance on data from the literature rather than actual measurements of the sites considered, assuming comparability of the sites. However, the results of studies such as this, in conjunction with ecological, socioeconomic and equity considerations

  4. Blood gas strategies and management during pediatric cardiopulmonary bypass.

    PubMed

    Griffin, Dee Ann

    2005-01-01

    Blood gas management during hypothermic cardiopulmonary bypass may be corrected by pH stat or alpha stat strategy. The pH stat philosophy is to maintain the blood pH constant at any temperature. Carbon dioxide must be introduced to the oxygenator in order to maintain the pH and pCO2 during hypothermic cardiopulmonary bypass. Conversely, during alpha stat blood gas management pH is maintained according to 37 degrees C despite the patient temperature. Alpha stat management preserves intracellular pH and autoregulation of cerebral vasculature by following the natural shift of the oxyhemoglobin dissociation curve. In-line blood gas analysis is a practical tool in assessing adequate blood gas management, because this technology provides immediate detection for modification of air/oxygen/carbon dioxide parameters. Results from several studies favor the pH stat strategy during neonatal cardiopulmonary bypass. This strategy increases tissue oxygenation and cerebral blood flow while cooling. Data also suggest that pH stat management results in better outcomes with shorter ventilation times and intensive care unit stays after pediatric cardiac surgery. PMID:16322734

  5. Greenhouse Emission Reductions and Natural Gas Vehicles: A Resource Guide on Technology Options and Project Development

    SciTech Connect

    Orestes Anastasia; NAncy Checklick; Vivianne Couts; Julie Doherty; Jette Findsen; Laura Gehlin; Josh Radoff

    2002-09-01

    Accurate and verifiable emission reductions are a function of the degree of transparency and stringency of the protocols employed in documenting project- or program-associated emissions reductions. The purpose of this guide is to provide a background for law and policy makers, urban planners, and project developers working with the many Greenhouse Gas (GHG) emission reduction programs throughout the world to quantify and/or evaluate the GHG impacts of Natural Gas Vehicle (NGVs). In order to evaluate the GHG benefits and/or penalties of NGV projects, it is necessary to first gain a fundamental understanding of the technology employed and the operating characteristics of these vehicles, especially with regard to the manner in which they compare to similar conventional gasoline or diesel vehicles. Therefore, the first two sections of this paper explain the basic technology and functionality of NGVs, but focus on evaluating the models that are currently on the market with their similar conventional counterparts, including characteristics such as cost, performance, efficiency, environmental attributes, and range. Since the increased use of NGVs, along with Alternative Fuel Vehicle (AFVs) in general, represents a public good with many social benefits at the local, national, and global levels, NGVs often receive significant attention in the form of legislative and programmatic support. Some states mandate the use of NGVs, while others provide financial incentives to promote their procurement and use. Furthermore, Federal legislation in the form of tax incentives or procurement requirements can have a significant impact on the NGV market. In order to implement effective legislation or programs, it is vital to have an understanding of the different programs and activities that already exist so that a new project focusing on GHG emission reduction can successfully interact with and build on the experience and lessons learned of those that preceded it. Finally, most programs

  6. A cost-benefit analysis of produced water management opportunities in selected unconventional oil and gas plays

    NASA Astrophysics Data System (ADS)

    Marsters, P.; Macknick, J.; Bazilian, M.; Newmark, R. L.

    2013-12-01

    Unconventional oil and gas production in North America has grown enormously over the past decade. The combination of horizontal drilling and hydraulic fracturing has made production from shale and other unconventional resources economically attractive for oil and gas operators, but has also resulted in concerns over potential water use and pollution issues. Hydraulic fracturing operations must manage large volumes of water on both the front end as well as the back end of operations, as significant amounts of water are coproduced with hydrocarbons. This water--often called flowback or produced water--can contain chemicals from the hydraulic fracturing fluid, salts dissolved from the source rock, various minerals, volatile organic chemicals, and radioactive constituents, all of which pose potential management, safety, and public health issues. While the long-term effects of hydraulic fracturing on aquifers, drinking water supplies, and surface water resources are still being assessed, the immediate impacts of produced water on local infrastructure and water supplies are readily evident. Produced water management options are often limited to underground injection, disposal at centralized treatment facilities, or recycling for future hydraulic fracturing operations. The costs of treatment, transport, and recycling are heavily dependent on local regulations, existing infrastructure, and technologies utilized. Produced water treatment costs also change over time during energy production as the quality of the produced water often changes. To date there is no publicly available model that evaluates the cost tradeoffs associated with different produced water management techniques in different regions. This study addresses that gap by characterizing the volume, qualities, and temporal dynamics of produced water in several unconventional oil and gas plays; evaluating potential produced water management options, including reuse and recycling; and assessing how hydraulic

  7. 40 CFR Appendix E to Part 75 - Optional NOX Emissions Estimation Protocol for Gas-Fired Peaking Units and Oil-Fired Peaking Units

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 17 2013-07-01 2013-07-01 false Optional NOX Emissions Estimation Protocol for Gas-Fired Peaking Units and Oil-Fired Peaking Units E Appendix E to Part 75 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTINUOUS...

  8. Assessment of Greenhouse Gas Control Technology Options within the Energy, Water and Food Nexus

    NASA Astrophysics Data System (ADS)

    Al-Ansari, Tareq; Korre, Anna; Nie, Zhenggang; Shah, Nilay

    2015-04-01

    The utilisation of Energy, Water and Food (EWF) resources can be described as a nexus of complex linkages embodied in industrial and natural processes. Food production is one such example of a system that mobilises EWF resources to deliver a product which is highly influenced by the efficiency of the industrial processes contributing to it and the conditions of the surrounding natural environment. Aggregating the utilisation of EWF resources into interconnected sub-systems is necessary for the accurate representation of the system's dynamics in terms of its material flow and resource consumption. The methodology used in this study is an extension of previous work developed regarding nexus analysis (Al-Ansari et al. 2014a, Al-Ansari et al. 2014b). Life cycle assessment (LCA) is used to prepare detailed models of the sub-system components, determine the linkages between the different nexus constituents and evaluate impacts on the natural environment. The nexus system is comprised of water sub-systems represented by a reverse osmosis (RO) desalination process. Energy sub-systems for power generation include models for a combined cycle gas turbine (CCGT) and solar Photovoltaics (PV) energy generation, as well as an amine based CO2 capture process enabling the utilisation of CO2 for the artificial fertilization of crops. The agricultural sub-systems include the production and application of fertilizers and the raising of livestock. A biomass integrated gasification combined cycle (BIGCC) for power generation using waste manure from the livestock sub-system is also included. The objective of this study is to consider a conventional food system in Qatar and enhance its environmental performance by using a nexus approach to examine different scenarios and operating modes. For the Qatar case study, three scenarios and four modes of operation were developed as part of the analysis. The baseline scenario uses fossil fuel to power the entire EWF nexus system using CCGT, the

  9. EMERGING TECHNOLOGIES FOR THE MANAGEMENT AND UTILIZATION OF LANDFILL GAS

    EPA Science Inventory

    The report gives information on emerging technologies that are considered to be commercially available (Tier 1), currently undergoing research and development (Tier 2), or considered as potentially applicable (Tier 3) for the management of landfill gas (LFG) emissions or for the ...

  10. Life cycle greenhouse gas impacts of grassland management practice

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Biomass from conservation and dedicated grasslands could be an important feedstock for biofuels. Estimating the carbon (C) intensity of biofuel production pathways is important in order to meet greenhouse gas (GHG) targets set by government policy. Management decisions made during feedstock producti...