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Sample records for gendered digital brain

  1. Gender and the Injured Brain

    PubMed Central

    Vagnerova, Kamila; Koerner, Ines P.; Hurn, Patricia D.

    2009-01-01

    Anesthesiologists are frequently confronted with patients who are at risk for neurological complications due to perioperative stroke or prior traumatic brain injury. In this review, we address the growing and fascinating body of data that suggests gender and sex steroids influence the pathophysiology of injury and outcome for these patients. Cerebral ischemia, traumatic brain injury, and epilepsy are reviewed in the context of potential sex differences in mechanisms and outcomes of brain injury and the role of estrogen, progesterone, and androgens in shaping these processes. Lastly, implications for current and future perioperative and intensive care are identified. PMID:18635489

  2. Promoting Gender Equality in Digital Literacy

    ERIC Educational Resources Information Center

    Ertl, Bernhard; Helling, Kathrin

    2011-01-01

    This article deals with gender phenomena in the context of digital literacy. Studies show that computer use, computer skills, and computer-related self-concepts are subject to gender differences. These differences may affect classroom interactions as well as learning processes and have therefore to be considered carefully by teachers who apply…

  3. The Digital Divide: The Special Case of Gender

    ERIC Educational Resources Information Center

    Cooper, J.

    2006-01-01

    This paper examines the evidence for the digital divide based on gender. An overview of research published in the last 20 years draws to the conclusion that females are at a disadvantage relative to men when learning about computers or learning other material with the aid of computer-assisted software. The evidence shows that the digital divide…

  4. The Digital Revolution and Adolescent Brain Evolution

    PubMed Central

    Giedd, Jay N.

    2012-01-01

    Remarkable advances in technologies that enable the distribution and utilization of information encoded as digital sequences of 1s or 0s have dramatically changed our way of life. Adolescents, old enough to master the technologies and young enough to welcome their novelty, are at the forefront of this “digital revolution”. Underlying the adolescent’s eager embracement of these sweeping changes is neurobiology forged byte fires of evolution to be extremely adept at adaptation. The consequences of the brains adaptation to the demands and opportunities of the digital age have enormous implications for adolescent health professionals. PMID:22824439

  5. Traumatic brain injury: Does gender influence outcomes?

    PubMed Central

    Munivenkatappa, Ashok; Agrawal, Amit; Shukla, Dhaval P.; Kumaraswamy, Deepika; Devi, Bhagavatula Indira

    2016-01-01

    Background: Traumatic brain injury (TBI) is a major public health problem. Both genders are affected, but little is known about female TBI. The present study exclusively explores epidemiological, clinical, imaging, and death aspects of female TBI, and how it differs from males. Methods: It is a retrospective study. Data were documented from a tertiary institute during January 2010 to March 2010. All variables were documented on standard proforma. The data were analyzed using R statistics software. Age group was categorized into pediatric (<18 years), middle (19–60 years) and elderly (>61 years). Significance was tested using Chi-square test at the significance level of P < 0.05. Results: Data of 1627 TBI patients were recorded. Of the total, female TBIs contributed nearly 20%. Compared to males, female patients reported higher percentages in manifesting symptoms (84.3% vs. 82.6%), injuries due to fall (32.1% vs. 24.4%), and surgical interventions (11.6% vs. 10.4%). Female patients were significantly higher in mild head injury group (76.8% vs. 69.5%, P - 0.016) and mortality (3.4% vs. 1.6%, P - 0.048). Number of patients and deaths was more among females than males in pediatric and elderly age group. Severities of injuries were more among female patients than male patients in middle and elder age groups. Conclusion: The study results observe that female TBI group differ significantly in the severity of injury and mortality. PMID:27308254

  6. Gender Differences and Styles in the Use of Digital Games

    ERIC Educational Resources Information Center

    Bonanno, Philip; Kommers, P. A. M.

    2005-01-01

    This paper reports work in progress investigating gender differences and styles in the use of digital games amongst advanced level biology students. It is an elaboration on previous work exploring the relationship between cognitive style and academic performance in Maltese students taking biology at advanced level. In this previous work the…

  7. Engaging Gender: Student Application of Theory through Digital Storytelling

    ERIC Educational Resources Information Center

    Coventry, Michael

    2008-01-01

    Enabling students' engagement with gender theory can be a difficult task. One of the best ways to help students learn difficult conceptual material, such as theoretical texts, is to provide them with opportunities to state and restate those ideas in multiple ways and through multiple means. Digital storytelling provides an effective pedagogy that…

  8. Sex, Gender, and Traumatic Brain Injury: A Commentary.

    PubMed

    Colantonio, Angela

    2016-02-01

    The goal of this supplemental issue is to address major knowledge, research, and clinical practice gaps regarding the limited focus on brain injury in girls and women as well as limited analysis of the effect of sex and gender in research on acquired brain injury. Integrating sex and gender in research is recognized as leading to better science and, ultimately, to better clinical practice. A sex and gender analytical approach to rehabilitation research is crucial to understanding traumatic brain injury and improving quality of life outcomes for survivors. Put another way, the lack of focus on sex and gender reduces the rigor of research design, the generalizability of study findings, and the effectiveness of clinical implementation and knowledge dissemination practices. The articles in this supplement examine sex and gender using a variety of methodological approaches and research contexts. Recommendations for future research on acquired brain injury that consciously incorporates sex and gender are made throughout this issue. This supplement is a product of the Girls and Women with ABI Task Force of the American Congress of Rehabilitation Medicine. PMID:26804988

  9. Empathy: gender effects in brain and behavior.

    PubMed

    Christov-Moore, Leonardo; Simpson, Elizabeth A; Coudé, Gino; Grigaityte, Kristina; Iacoboni, Marco; Ferrari, Pier Francesco

    2014-10-01

    Evidence suggests that there are differences in the capacity for empathy between males and females. However, how deep do these differences go? Stereotypically, females are portrayed as more nurturing and empathetic, while males are portrayed as less emotional and more cognitive. Some authors suggest that observed gender differences might be largely due to cultural expectations about gender roles. However, empathy has both evolutionary and developmental precursors, and can be studied using implicit measures, aspects that can help elucidate the respective roles of culture and biology. This article reviews evidence from ethology, social psychology, economics, and neuroscience to show that there are fundamental differences in implicit measures of empathy, with parallels in development and evolution. Studies in nonhuman animals and younger human populations (infants/children) offer converging evidence that sex differences in empathy have phylogenetic and ontogenetic roots in biology and are not merely cultural byproducts driven by socialization. We review how these differences may have arisen in response to males' and females' different roles throughout evolution. Examinations of the neurobiological underpinnings of empathy reveal important quantitative gender differences in the basic networks involved in affective and cognitive forms of empathy, as well as a qualitative divergence between the sexes in how emotional information is integrated to support decision making processes. Finally, the study of gender differences in empathy can be improved by designing studies with greater statistical power and considering variables implicit in gender (e.g., sexual preference, prenatal hormone exposure). These improvements may also help uncover the nature of neurodevelopmental and psychiatric disorders in which one sex is more vulnerable to compromised social competence associated with impaired empathy. PMID:25236781

  10. Gender effects on brain changes in early-onset psychosis.

    PubMed

    Rapado-Castro, Marta; Bartholomeusz, Cali F; Castro-Fornieles, Josefina; González-Pinto, Ana; Otero, Soraya; Baeza, Inmaculada; Moreno, Carmen; Graell, Montserrat; Janssen, Joost; Bargalló, Nuria; Pantelis, Christos; Desco, Manuel; Arango, Celso

    2015-10-01

    Progressive loss of cortical gray matter (GM) and increase of cerebrospinal fluid (CSF) have been reported in early-onset psychosis (EOP). EOP typically begins during adolescence, a time when developmental brain trajectories differ by gender. This study aimed to determine gender differences in progression of brain changes in this population. A sample of 61 (21 females) adolescents with a first psychotic episode and a matched sample of 70 (23 females) controls underwent both baseline and 2-year follow-up anatomical brain imaging assessments. Regional GM and CSF volumes were obtained using automated methods based on the Talairach's proportional grid system. At baseline, only male patients showed a clear pattern of alterations in the frontal lobe relative to controls (smaller GM and larger CSF volumes). However, parallel longitudinal changes for male and female patients relative to controls were observed, resulting in a common pattern of brain changes across both genders: rate of left frontal lobe GM volume loss was larger in male (-3.8%) and female patients (-4.2%) than in controls (-0.7% males; -0.4% females). The reverse was found for the CSF volume in the left frontal lobe. While the GM and CSF volumes of females with EOP appear to be within the normal range at initial illness onset, our results point to a similar trajectory of increased/accelerated brain changes in both male and female patients with EOP. The pattern of progression of brain changes in psychosis appears to be independent of gender or structural alterations on appearance of psychotic symptoms. PMID:25589436

  11. Own-gender imitation activates the brain's reward circuitry

    PubMed Central

    Iacoboni, Macro; Martin, Alia; Dapretto, Mirella

    2012-01-01

    Imitation is an important component of human social learning throughout life. Theoretical models and empirical data from anthropology and psychology suggest that people tend to imitate self-similar individuals, and that such imitation biases increase the adaptive value (e.g., self-relevance) of learned information. It is unclear, however, what neural mechanisms underlie people's tendency to imitate those similar to themselves. We focused on the own-gender imitation bias, a pervasive bias thought to be important for gender identity development. While undergoing fMRI, participants imitated own- and other-gender actors performing novel, meaningless hand signs; as control conditions, they also simply observed such actions and viewed still portraits of the same actors. Only the ventral and dorsal striatum, orbitofrontal cortex and amygdala were more active when imitating own- compared to other-gender individuals. A Bayesian analysis of the BrainMap neuroimaging database demonstrated that the striatal region preferentially activated by own-gender imitation is selectively activated by classical reward tasks in the literature. Taken together, these findings reveal a neurobiological mechanism associated with the own-gender imitation bias and demonstrate a novel role of reward-processing neural structures in social behavior. PMID:22383803

  12. Brain-Based Teaching in the Digital Age

    ERIC Educational Resources Information Center

    Sprenger, Marilee

    2010-01-01

    In the digital age, your students have the ways, means, and speed to gather any information they want. But they need your guidance more than ever. Discover how digital technology is actually changing your students' brains. Learn why this creates new obstacles for teachers, but also opens up potential new pathways for learning. You will understand…

  13. Gender Differences in Directional Brain Responses to Infant Hunger Cries

    PubMed Central

    De Pisapia, Nicola; Bornstein, Marc H.; Rigo, Paola; Esposito, Gianluca; De Falco, Simona; Venuti, Paola

    2013-01-01

    Infant cries are a critical survival mechanism that draw the attention of adult caregivers, who can then satisfy the basic needs of otherwise helpless infants. Here, we used functional neuroimaging to investigate the effects of infant hunger cries on brain activity of adults who were in a cognitively non-demanding mental state of awake rest. We found that the brains of males and females, independent of parental status (parent or non parent), reacted differently to infant cries. Specifically, dorsal medial prefrontal and posterior cingulate areas, known to be involved in mind-wandering (the stream of thought typical of awake rest), remained active in men during exposure to infant cries, whereas in women activity in these regions decreased. These results reveal gender-dependent modulation of brain responses to infant requests to be fed, and specifically they indicate that women interrupt mind-wandering when exposed to the sounds of infant hunger cries, whereas men carry on without interruption. PMID:23282991

  14. Brain responses mediating idiom comprehension: gender and hemispheric differences.

    PubMed

    Kana, Rajesh K; Murdaugh, Donna L; Wolfe, Kelly R; Kumar, Sandhya L

    2012-07-27

    Processing figurative language, such as idioms, is unique in that it requires one to make associations between words and non-literal meanings that are contextually appropriate. At the neural level, processing idiomatic phrases has been linked to recruitment of bilateral dorsolateral prefrontal cortices (DLPFC), the left temporal cortex, superior medial prefrontal gyrus (MPFC), and the left inferior frontal gyrus (LIFG). This functional MRI study examined the brain responses associated with processing idiomatic compared to literal sentences. In addition, gender differences in neural responses associated with language comprehension were also explored. In an fMRI scanner, thirty-six healthy adult volunteers viewed sentences that were either literal or idiomatic in nature, and answered subsequent comprehension questions. This sentence comprehension tasks activated mainly prefrontal language areas (LIFG, LSFG, and RMFG). Consistent with previous findings, idiomatic sentences showed increased response in LIFG. These results are discussed in the backdrop of the graded salience hypothesis. Furthermore, we found gender differences in brain activation and functional connectivity during this task. Women showed greater overall activation than men when comprehending literal and idiomatic sentences; whereas men had significantly greater functional connectivity between LIFG and LMTG than women across tasks. Overall, the findings of this study highlight the gender differences in neural responses associated with figurative language comprehension. PMID:22634066

  15. BrainMaps.org - Interactive High-Resolution Digital Brain Atlases and Virtual Microscopy.

    PubMed

    Mikula, Shawn; Stone, James M; Jones, Edward G

    2008-01-01

    BrainMaps.org is an interactive high-resolution digital brain atlas and virtual microscope that is based on over 20 million megapixels of scanned images of serial sections of both primate and non-primate brains and that is integrated with a high-speed database for querying and retrieving data about brain structure and function over the internet. Complete brain datasets for various species, including Homo sapiens, Macaca mulatta, Chlorocebus aethiops, Felis catus, Mus musculus, Rattus norvegicus, and Tyto alba, are accessible online. The methods and tools we describe are useful for both research and teaching, and can be replicated by labs seeking to increase accessibility and sharing of neuroanatomical data. These tools offer the possibility of visualizing and exploring completely digitized sections of brains at a sub-neuronal level, and can facilitate large-scale connectional tracing, histochemical and stereological analyses. PMID:19129928

  16. The Gender and Science Digital Library: Affecting Student Achievement in Science.

    ERIC Educational Resources Information Center

    Nair, Sarita

    2003-01-01

    Describes the Gender and Science Digital Library (GSDL), an online collection of high-quality, interactive science resources that are gender-fair, inclusive, and engaging to students. Considers use by teachers and school library media specialists to encourage girls to enter careers in science, technology, engineering, and math (STEM). (LRW)

  17. A Digital Atlas of the Dog Brain

    PubMed Central

    Datta, Ritobrato; Lee, Jongho; Duda, Jeffrey; Avants, Brian B.; Vite, Charles H.; Tseng, Ben; Gee, James C.; Aguirre, Gustavo D.; Aguirre, Geoffrey K.

    2012-01-01

    There is a long history and a growing interest in the canine as a subject of study in neuroscience research and in translational neurology. In the last few years, anatomical and functional magnetic resonance imaging (MRI) studies of awake and anesthetized dogs have been reported. Such efforts can be enhanced by a population atlas of canine brain anatomy to implement group analyses. Here we present a canine brain atlas derived as the diffeomorphic average of a population of fifteen mesaticephalic dogs. The atlas includes: 1) A brain template derived from in-vivo, T1-weighted imaging at 1 mm isotropic resolution at 3 Tesla (with and without the soft tissues of the head); 2) A co-registered, high-resolution (0.33 mm isotropic) template created from imaging of ex-vivo brains at 7 Tesla; 3) A surface representation of the gray matter/white matter boundary of the high-resolution atlas (including labeling of gyral and sulcal features). The properties of the atlas are considered in relation to historical nomenclature and the evolutionary taxonomy of the Canini tribe. The atlas is available for download (https://cfn.upenn.edu/aguirre/wiki/public:data_plosone_2012_datta). PMID:23284904

  18. Spatial Rotation and Recognizing Emotions: Gender Related Differences in Brain Activity

    ERIC Educational Resources Information Center

    Jausovec, Norbert; Jausovec, Ksenija

    2008-01-01

    In three experiments, gender and ability (performance and emotional intelligence) related differences in brain activity--assessed with EEG methodology--while respondents were solving a spatial rotation tasks and identifying emotions in faces were investigated. The most robust gender related difference in brain activity was observed in the lower-2…

  19. Implementation of age and gender recognition system for intelligent digital signage

    NASA Astrophysics Data System (ADS)

    Lee, Sang-Heon; Sohn, Myoung-Kyu; Kim, Hyunduk

    2015-12-01

    Intelligent digital signage systems transmit customized advertising and information by analyzing users and customers, unlike existing system that presented advertising in the form of broadcast without regard to type of customers. Currently, development of intelligent digital signage system has been pushed forward vigorously. In this study, we designed a system capable of analyzing gender and age of customers based on image obtained from camera, although there are many different methods for analyzing customers. We conducted age and gender recognition experiments using public database. The age/gender recognition experiments were performed through histogram matching method by extracting Local binary patterns (LBP) features after facial area on input image was normalized. The results of experiment showed that gender recognition rate was as high as approximately 97% on average. Age recognition was conducted based on categorization into 5 age classes. Age recognition rates for women and men were about 67% and 68%, respectively when that conducted separately for different gender.

  20. ICTs and Gender. OECD Digital Economy Papers, No. 129

    ERIC Educational Resources Information Center

    van Welsum, Desiree; Montagnier, Pierre

    2007-01-01

    This document provides an overview of the gender distribution of ICT and ICT-related employment in OECD countries, and ICT employment patterns are contrasted with overall employment to highlight differences. The authors discuss participation in ICT-related education and training, and differences in ICT access and use by gender. Overall,…

  1. A Mixed-Method Approach on Digital Educational Games for K12: Gender, Attitudes and Performance

    NASA Astrophysics Data System (ADS)

    Law, Effie Lai-Chong; Gamble, Tim; Schwarz, Daniel; Kickmeier-Rust, Michael D.; Holzinger, Andreas

    Research on the influence of gender on attitudes towards and performance in digital educational games (DEGs) has quite a long history. Generally, males tend to play such games more engagingly than females, consequently attitude and performance of males using DEGs should be presumably higher than that of females. This paper reports an investigation of a DEG, which was developed to enhance the acquisition of geographical knowledge, carried out on British, German and Austrian K12 students aged between 11 and 14. Methods include a survey on initial design concepts, user tests on the system and two single-gender focus groups. Gender and cultural differences in gameplay habit, game type preferences and game character perceptions were observed. The results showed that both genders similarly improved their geographical knowledge, although boys tended to have a higher level of positive user experience than the girls. The qualitative data from the focus groups illustrated some interesting gender differences in perceiving various aspects of the game.

  2. The Extreme Male Brain Theory and Gender Role Behaviour in Persons with an Autism Spectrum Condition

    ERIC Educational Resources Information Center

    Stauder, J. E. A.; Cornet, L. J. M.; Ponds, R. W. H. M.

    2011-01-01

    According to the Extreme Male Brain theory persons with autism possess masculinised cognitive traits. In this study masculinisation of gender role behaviour is evaluated in 25 persons with an autism spectrum condition (ASC) and matched controls with gender role behaviour as part of a shortened version of the Minnesota Multiphasic Personality…

  3. Anticipating Words and Their Gender: An Event-related Brain Potential Study of Semantic Integration, Gender Expectancy, and Gender Agreement in Spanish Sentence Reading

    PubMed Central

    Wicha, Nicole Y. Y.; Moreno, Eva M.; Kutas, Marta

    2012-01-01

    Recent studies indicate that the human brain attends to and uses grammatical gender cues during sentence comprehension. Here, we examine the nature and time course of the effect of gender on word-by-word sentence reading. Event-related brain potentials were recorded to an article and noun, while native Spanish speakers read medium- to high-constraint Spanish sentences for comprehension. The noun either fit the sentence meaning or not, and matched the preceding article in gender or not; in addition, the preceding article was either expected or unexpected based on prior sentence context. Semantically anomalous nouns elicited an N400. Gender-disagreeing nouns elicited a posterior late positivity (P600), replicating previous findings for words. Gender agreement and semantic congruity interacted in both the N400 window—with a larger negativity frontally for double violations—and the P600 window—with a larger positivity for semantic anomalies, relative to the prestimulus baseline. Finally, unexpected articles elicited an enhanced positivity (500–700 msec post onset) relative to expected articles. Overall, our data indicate that readers anticipate and attend to the gender of both articles and nouns, and use gender in real time to maintain agreement and to build sentence meaning. PMID:15453979

  4. Persistence of Gender Related-Effects on Visuo-Spatial and Verbal Working Memory in Right Brain-Damaged Patients

    PubMed Central

    Piccardi, Laura; Matano, Alessandro; D’Antuono, Giovanni; Marin, Dario; Ciurli, Paola; Incoccia, Chiara; Verde, Paola; Guariglia, Paola

    2016-01-01

    The aim of the present study was to verify if gender differences in verbal and visuo-spatial working memory would persist following right cerebral lesions. To pursue our aim we investigated a large sample (n. 346) of right brain-damaged patients and healthy participants (n. 272) for the presence of gender effects in performing Corsi and Digit Test. We also assessed a subgroup of patients (n. 109) for the nature (active vs. passive) of working memory tasks. We tested working memory (WM) administering the Corsi Test (CBT) and the Digit Span (DS) using two different versions: forward (fCBT and fDS), subjects were required to repeat stimuli in the same order that they were presented; and backward (bCBT and bDS), subjects were required to repeat stimuli in the opposite order of presentation. In this way, passive storage and active processing of working memory were assessed. Our results showed the persistence of gender-related effects in spite of the presence of right brain lesions. We found that men outperformed women both in CBT and DS, regardless of active and passive processing of verbal and visuo-spatial stimuli. The presence of visuo-spatial disorders (i.e., hemineglect) can affect the performance on Corsi Test. In our sample, men and women were equally affected by hemineglect, therefore it did not mask the gender effect. Generally speaking, the persistence of the men’s superiority in visuo-spatial tasks may be interpreted as a protective factor, at least for men, within other life factors such as level of education or kind of profession before retirement. PMID:27445734

  5. Persistence of Gender Related-Effects on Visuo-Spatial and Verbal Working Memory in Right Brain-Damaged Patients.

    PubMed

    Piccardi, Laura; Matano, Alessandro; D'Antuono, Giovanni; Marin, Dario; Ciurli, Paola; Incoccia, Chiara; Verde, Paola; Guariglia, Paola

    2016-01-01

    The aim of the present study was to verify if gender differences in verbal and visuo-spatial working memory would persist following right cerebral lesions. To pursue our aim we investigated a large sample (n. 346) of right brain-damaged patients and healthy participants (n. 272) for the presence of gender effects in performing Corsi and Digit Test. We also assessed a subgroup of patients (n. 109) for the nature (active vs. passive) of working memory tasks. We tested working memory (WM) administering the Corsi Test (CBT) and the Digit Span (DS) using two different versions: forward (fCBT and fDS), subjects were required to repeat stimuli in the same order that they were presented; and backward (bCBT and bDS), subjects were required to repeat stimuli in the opposite order of presentation. In this way, passive storage and active processing of working memory were assessed. Our results showed the persistence of gender-related effects in spite of the presence of right brain lesions. We found that men outperformed women both in CBT and DS, regardless of active and passive processing of verbal and visuo-spatial stimuli. The presence of visuo-spatial disorders (i.e., hemineglect) can affect the performance on Corsi Test. In our sample, men and women were equally affected by hemineglect, therefore it did not mask the gender effect. Generally speaking, the persistence of the men's superiority in visuo-spatial tasks may be interpreted as a protective factor, at least for men, within other life factors such as level of education or kind of profession before retirement. PMID:27445734

  6. Appropriation, Parody, Gender Play, and Self-Representation in Preadolescents' Digital Video Production

    ERIC Educational Resources Information Center

    Ivashkevich, Olga; Shoppell, Samantha

    2013-01-01

    The authors discuss their participant observation study with the 10-year-old boy and 8-year-old girl who collaborated on making digital videos at home. Major themes that emerged from this research include appropriation of popular culture texts, parody, gender play, and managing self-representations. These themes highlight the benefits of video…

  7. A three-dimensional digital atlas of the zebrafish brain.

    PubMed

    Ullmann, Jeremy F P; Cowin, Gary; Kurniawan, Nyoman D; Collin, Shaun P

    2010-05-15

    In the past three decades, the zebrafish has become a vital animal model in a range of biological sciences. To augment current neurobiological research, we have developed the first three-dimensional digital atlas of the zebrafish brain from T2-weighted magnetic resonance histology (MRH) images acquired on a 16.4-T superconducting magnet. We achieved an isotropic resolution of 10 microm, which is the highest resolution achieved in a vertebrate brain and, for the first time, is comparable in slice thickness to conventional histology. By using manual segmentation, 53 anatomical structures, including fiber tracts as small as 40 microm, were delineated. Using Amira software, structures were also individually segmented and reconstructed to create three-dimensional animations. Additional quantitative information including, volume, surface areas, and mean gray scale intensities were also determined. Finally, we established a stereotaxic coordinate system as a framework in which maps created from other modalities can be incorporated into the atlas. PMID:20139016

  8. Internet Activities and Developmental Predictors: Gender Differences among Digital Natives

    ERIC Educational Resources Information Center

    Johnson, Genevieve Marie

    2011-01-01

    Widespread adoption of the Internet during the past two decades has produced the first generation of digital natives. Ninety-five children (M[subscript age] = 10.4 years) completed a questionnaire that measured three clusters of variables: 1) Internet use at home and school, 2) peer, school, and home self-esteem, 3) and cognitive abilities…

  9. Gender differences in self reported long term outcomes following moderate to severe traumatic brain injury

    PubMed Central

    2010-01-01

    Background The majority of research on health outcomes after a traumatic brain injury is focused on male participants. Information examining gender differences in health outcomes post traumatic brain injury is limited. The purpose of this study was to investigate gender differences in symptoms reported after a traumatic brain injury and to examine the degree to which these symptoms are problematic in daily functioning. Methods This is a secondary data analysis of a retrospective cohort study of 306 individuals who sustained a moderate to severe traumatic brain injury 8 to 24 years ago. Data were collected using the Problem Checklist (PCL) from the Head Injury Family Interview (HIFI). Using Bonferroni correction, group differences between women and men were explored using Chi-square and Wilcoxon analysis. Results Chi-square analysis by gender revealed that significantly more men reported difficulty setting realistic goals and restlessness whereas significantly more women reported headaches, dizziness and loss of confidence. Wilcoxon analysis by gender revealed that men reported sensitivity to noise and sleep disturbances as significantly more problematic than women, whereas for women, lack of initiative and needing supervision were significantly more problematic in daily functioning. Conclusion This study provides insight into gender differences on outcomes after traumatic brain injury. There are significant differences between problems reported by men compared to women. This insight may facilitate health service planners and clinicians when developing programs for individuals with brain injury. PMID:21029463

  10. "Brains before "Beauty"?" High Achieving Girls, School and Gender Identities

    ERIC Educational Resources Information Center

    Skelton, Christine; Francis, Becky; Read, Barbara

    2010-01-01

    In recent years educational policy on gender and achievement has concentrated on boys' underachievement, frequently comparing it with the academic success of girls. This has encouraged a perception of girls as the "winners" of the educational stakes and assumes that they no longer experience the kinds of gender inequalities identified in earlier…

  11. Race, gender, and information technology use: the new digital divide.

    PubMed

    Jackson, Linda A; Zhao, Yong; Kolenic, Anthony; Fitzgerald, Hiram E; Harold, Rena; Von Eye, Alexander

    2008-08-01

    This research examined race and gender differences in the intensity and nature of IT use and whether IT use predicted academic performance. A sample of 515 children (172 African Americans and 343 Caucasian Americans), average age 12 years old, completed surveys as part of their participation in the Children and Technology Project. Findings indicated race and gender differences in the intensity of IT use; African American males were the least intense users of computers and the Internet, and African American females were the most intense users of the Internet. Males, regardless of race, were the most intense videogame players, and females, regardless of race, were the most intense cell phone users. IT use predicted children's academic performance. Length of time using computers and the Internet was a positive predictor of academic performance, whereas amount of time spent playing videogames was a negative predictor. Implications of the findings for bringing IT to African American males and bringing African American males to IT are discussed. PMID:18721092

  12. Gender and environmental effects on regional brain-derived neurotrophic factor expression after experimental traumatic brain injury.

    PubMed

    Chen, X; Li, Y; Kline, A E; Dixon, C E; Zafonte, R D; Wagner, A K

    2005-01-01

    Alterations in brain-derived neurotrophic factor expression have been reported in multiple brain regions acutely after traumatic brain injury, however neither injury nor post-injury environmental enrichment has been shown to affect hippocampal brain-derived neurotrophic factor gene expression in male rats chronically post-injury. Studies have demonstrated hormone-related neuroprotection for female rats after traumatic brain injury, and estrogen and exercise both influence brain-derived neurotrophic factor levels. Despite recent studies suggesting that exposure post-traumatic brain injury to environmental enrichment improves cognitive recovery in male rats, we have shown that environmental enrichment mediated improvements with spatial learning are gender specific and only positively affect males. Therefore the purpose of this study was to evaluate the effect of gender and environmental enrichment on chronic post-injury cortical and hippocampal brain-derived neurotrophic factor protein expression. Sprague-Dawley male and cycling female rats were placed into environmental enrichment or standard housing after controlled cortical impact or sham surgery. Four weeks post-surgery, hippocampal and frontal cortex brain-derived neurotrophic factor expression were examined using Western blot. Results revealed significant increases in brain-derived neurotrophic factor expression in the frontal cortex ipsilateral to injury for males (P=0.03). Environmental enrichment did not augment this effect. Neither environmental enrichment nor injury significantly affected cortical brain-derived neurotrophic factor expression for females. In the hippocampus ipsilateral to injury brain-derived neurotrophic factor expression for both males and females was half (49% and 51% respectively) of that observed in shams housed in the standard environment. For injured males, there was a trend in this region for environmental enrichment to restore brain-derived neurotrophic factor levels to sham values

  13. Male brain ages faster: the age and gender dependence of subcortical volumes.

    PubMed

    Király, András; Szabó, Nikoletta; Tóth, Eszter; Csete, Gergő; Faragó, Péter; Kocsis, Krisztián; Must, Anita; Vécsei, László; Kincses, Zsigmond Tamás

    2016-09-01

    Effects of gender on grey matter (GM) volume differences in subcortical structures of the human brain have consistently been reported. Recent research evidence suggests that both gender and brain size influences volume distribution in subcortical areas independently. The goal of this study was to determine the effects of the interplay between brain size, gender and age contributing to volume differences of subcortical GM in the human brain. High-resolution T1-weighted images were acquired from 53 healthy males and 50 age-matched healthy females. Total GM volume was determined using voxel-based morphometry. We used model-based subcortical segmentation analysis to measure the volume of subcortical nuclei. Main effects of gender, brain volume and aging on subcortical structures were examined using multivariate analysis of variance. No significant difference was found in total brain volume between the two genders after correcting for total intracranial volume. Our analysis revealed significantly larger hippocampus volume for females. Additionally, GM volumes of the caudate nucleus, putamen and thalamus displayed a significant age-related decrease in males as compared to females. In contrast to this only the thalamic volume loss proved significant for females. Strikingly, GM volume decreases faster in males than in females emphasizing the interplay between aging and gender on subcortical structures. These findings might have important implications for the interpretation of the effects of unalterable factors (i.e. gender and age) in cross-sectional structural MRI studies. Furthermore, the volume distribution and changes of subcortical structures have been consistently related to several neuropsychiatric disorders (e.g. Parkinson's disease, attention deficit hyperactivity disorder, etc.). Understanding these changes might yield further insight in the course and prognosis of these disorders. PMID:26572143

  14. Multichannel Brain-Signal-Amplifying and Digitizing System

    NASA Technical Reports Server (NTRS)

    Gevins, Alan

    2005-01-01

    An apparatus has been developed for use in acquiring multichannel electroencephalographic (EEG) data from a human subject. EEG apparatuses with many channels in use heretofore have been too heavy and bulky to be worn, and have been limited in dynamic range to no more than 18 bits. The present apparatus is small and light enough to be worn by the subject. It is capable of amplifying EEG signals and digitizing them to 22 bits in as many as 150 channels. The apparatus is controlled by software and is plugged into the USB port of a personal computer. This apparatus makes it possible, for the first time, to obtain high-resolution functional EEG images of a thinking brain in a real-life, ambulatory setting outside a research laboratory or hospital.

  15. High-resolution digital brain atlases: a Hubble telescope for the brain.

    PubMed

    Jones, Edward G; Stone, James M; Karten, Harvey J

    2011-05-01

    We describe implementation of a method for digitizing at microscopic resolution brain tissue sections containing normal and experimental data and for making the content readily accessible online. Web-accessible brain atlases and virtual microscopes for online examination can be developed using existing computer and internet technologies. Resulting databases, made up of hierarchically organized, multiresolution images, enable rapid, seamless navigation through the vast image datasets generated by high-resolution scanning. Tools for visualization and annotation of virtual microscope slides enable remote and universal data sharing. Interactive visualization of a complete series of brain sections digitized at subneuronal levels of resolution offers fine grain and large-scale localization and quantification of many aspects of neural organization and structure. The method is straightforward and replicable; it can increase accessibility and facilitate sharing of neuroanatomical data. It provides an opportunity for capturing and preserving irreplaceable, archival neurohistological collections and making them available to all scientists in perpetuity, if resources could be obtained from hitherto uninterested agencies of scientific support. PMID:21599693

  16. Cyberinfrastructure for the digital brain: spatial standards for integrating rodent brain atlases

    PubMed Central

    Zaslavsky, Ilya; Baldock, Richard A.; Boline, Jyl

    2014-01-01

    Biomedical research entails capture and analysis of massive data volumes and new discoveries arise from data-integration and mining. This is only possible if data can be mapped onto a common framework such as the genome for genomic data. In neuroscience, the framework is intrinsically spatial and based on a number of paper atlases. This cannot meet today's data-intensive analysis and integration challenges. A scalable and extensible software infrastructure that is standards based but open for novel data and resources, is required for integrating information such as signal distributions, gene-expression, neuronal connectivity, electrophysiology, anatomy, and developmental processes. Therefore, the International Neuroinformatics Coordinating Facility (INCF) initiated the development of a spatial framework for neuroscience data integration with an associated Digital Atlasing Infrastructure (DAI). A prototype implementation of this infrastructure for the rodent brain is reported here. The infrastructure is based on a collection of reference spaces to which data is mapped at the required resolution, such as the Waxholm Space (WHS), a 3D reconstruction of the brain generated using high-resolution, multi-channel microMRI. The core standards of the digital atlasing service-oriented infrastructure include Waxholm Markup Language (WaxML): XML schema expressing a uniform information model for key elements such as coordinate systems, transformations, points of interest (POI)s, labels, and annotations; and Atlas Web Services: interfaces for querying and updating atlas data. The services return WaxML-encoded documents with information about capabilities, spatial reference systems (SRSs) and structures, and execute coordinate transformations and POI-based requests. Key elements of INCF-DAI cyberinfrastructure have been prototyped for both mouse and rat brain atlas sources, including the Allen Mouse Brain Atlas, UCSD Cell-Centered Database, and Edinburgh Mouse Atlas Project. PMID

  17. The impact of aging and gender on brain viscoelasticity.

    PubMed

    Sack, Ingolf; Beierbach, Bernd; Wuerfel, Jens; Klatt, Dieter; Hamhaber, Uwe; Papazoglou, Sebastian; Martus, Peter; Braun, Jürgen

    2009-07-01

    Viscoelasticity is a sensitive measure of the microstructural constitution of soft biological tissue and is increasingly used as a diagnostic marker, e.g. in staging liver fibrosis or characterizing breast tumors. In this study, multifrequency magnetic resonance elastography was used to investigate the in vivo viscoelasticity of healthy human brain in 55 volunteers (23 females) ranging in age from 18 to 88 years. The application of four vibration frequencies in an acoustic range from 25 to 62.5 Hz revealed for the first time how physiological aging changes the global viscosity and elasticity of the brain. Using the rheological springpot model, viscosity and elasticity are combined in a parameter mu that describes the solid-fluid behavior of the tissue and a parameter alpha related to the tissue's microstructure. It is shown that the healthy adult brain undergoes steady parenchymal 'liquefaction' characterized by a continuous decline in mu of 0.8% per year (P<0.001), whereas alpha remains unchanged. Furthermore, significant sex differences were found with female brains being on average 9% more solid-like than their male counterparts rendering women more than a decade 'younger' than men with respect to brain mechanics (P=0.016). These results set the background for using cerebral multifrequency elastography in diagnosing subtle neurodegenerative processes not detectable by other diagnostic methods. PMID:19281851

  18. Gender differences in working memory networks: A BrainMap meta-analysis

    PubMed Central

    Hill, Ashley C.; Laird, Angela R.; Robinson, Jennifer L.

    2014-01-01

    Gender differences in psychological processes have been of great interest in a variety of fields. While the majority of research in this area has focused on specific differences in relation to test performance, this study sought to determine the underlying neurofunctional differences observed during working memory, a pivotal cognitive process shown to be predictive of academic achievement and intelligence. Using the BrainMap database, we performed a meta-analysis and applied activation likelihood estimation to our search set. Our results demonstrate consistent working memory networks across genders, but also provide evidence for gender-specific networks whereby females consistently activate more limbic (e.g., amygdala and hippocampus) and prefrontal structures (e.g., right inferior frontal gyrus), and males activate a distributed network inclusive of more parietal regions. These data provide a framework for future investigation using functional or effective connectivity methods to elucidate the underpinnings of gender differences in neural network recruitment during working memory tasks. PMID:25042764

  19. Perception of Suffering and Compassion Experience: Brain Gender Disparities

    ERIC Educational Resources Information Center

    Mercadillo, Roberto E.; Diaz, Jose Luis; Pasaye, Erick H.; Barrios, Fernando A.

    2011-01-01

    Compassion is considered a moral emotion related to the perception of suffering in others, and resulting in a motivation to alleviate the afflicted party. We compared brain correlates of compassion-evoking images in women and men. BOLD functional images of 24 healthy volunteers (twelve women and twelve men; age=27 [plus or minus] 2.5 y.o.) were…

  20. Prediction of age and gender using digital radiographic method: A retrospective study

    PubMed Central

    Poongodi, V.; Kanmani, R.; Anandi, M. S.; Krithika, C. L.; Kannan, A.; Raghuram, P. H.

    2015-01-01

    Aim and Objective: To investigate age, sex based on gonial angle, width and breadth of the ramus of the mandible by digital orthopantomograph. Materials and Methods: A total of 200 panoramic radiographic images were selected. The age of the individuals ranged between 4 and 75 years of both the gender - males (113) and females (87) and selected radiographic images were measured using KLONK image measurement software tool with linear, angular measurement. The investigated radiographs were collected from the records of SRM Dental College, Department of Oral Medicine and Radiology. Radiographs with any pathology, facial deformities, if no observation of mental foramen, congenital deformities, magnification, and distortion were excluded. Results: Mean, median, standard deviation, derived to check the first and third quartile, linear regression is used to check age and gender correlation with angle of mandible, height and width of the ramus of mandible. Conclusion: The radiographic method is a simpler and cost-effective method of age identification compared with histological and biochemical methods. Mandible is strongest facial bone after the skull, pelvic bone. It is validatory to predict age and gender by many previous studies. Radiographic and tomographic images have become an essential aid for human identification in forensic dentistry forensic dentists can choose the most appropriate one since the validity of age and gender estimation crucially depends on the method used and its proper application. PMID:26538907

  1. Hormones, context, and "brain gender": a review of evidence from congenital adrenal hyperplasia.

    PubMed

    Jordan-Young, Rebecca M

    2012-06-01

    Brain organization theory suggests that steroid hormones during fetal development permanently organize the brain for gender, including patterns of sexuality, cognition, temperament, and interests that differ by sex. This widely-accepted theory has important implications for health, ranging from medical management of infants with intersex conditions to suggested etiologies for sex differences in autism, depression, and other mental health problems. Studies of genetic females with congenital adrenal hyperplasia (CAH), in which high prenatal androgens have been linked to both atypical genitals and "masculine" patterns of gender and sexuality, are particularly important. Based on a comprehensive review of research on CAH, this article demonstrates that such studies have neglected four broad categories of variables that plausibly affect psychosexual development: (1) physiological effects of CAH, including complex disruption of steroid hormones from early development onwards; (2) intensive medical intervention and surveillance, which many women with CAH describe as traumatic; (3) direct effects of genital morphology on sexuality (versus indirect effects that "masculine" genitals may have on gender socialization); and (4) expectations of masculinization that likely affect both the development and evaluation of gender and sexuality in CAH. Complex and iterative interactions among postnatal biological variables, medical interventions, and social context provide a more plausible explanation for atypicalities in psychology and behavior that have been reported for genetic females with CAH than the conventional explanation that early androgens have "masculinized" their brains. PMID:21962724

  2. Brain activation in elderly people with and without dementia: Influences of gender and medication.

    PubMed

    Richter, Melany M; Herrmann, Martin J; Ehlis, Ann-Christine; Plichta, Michael M; Fallgatter, Andreas J

    2007-01-01

    Patients suffering from dementia show altered functional brain activation patterns especially in prefrontal brain regions, as research suggests. The present study follows three aims: to replicate these findings, to investigate treatment effects when administering galantamine, and to put gender differences in focus. We compared 12 patients with dementia to 12 age- and gender-matched healthy subjects regarding changes in haemoglobin concentration in brain tissue while performing a verbal fluency task (VFT). Concentration changes of oxygenated (O(2)Hb) and deoxygenated (HHb) haemoglobin were measured by multi-channel near-infrared spectroscopy (NIRS), an easily applicable and non-invasive method of optical topography. In the patient group, measurement was repeated 4 and 8 weeks after starting treatment with galantamine. The results showed a reduced increase in O(2)Hb during task performance for patients compared to healthy controls. Furthermore, female subjects showed more pronounced activation in O(2)Hb as well as HHb compared to male subjects. Regarding treatment effects, no clear results could be obtained. In HHb, evidence for an entrainment effect was found. In the light of existing literature, the present study suggests an interaction of gender and age regarding brain activation patterns which should be aimed at in future investigations. PMID:17366346

  3. EXPECTING GENDER: AN EVENT RELATED BRAIN POTENTIAL STUDY ON THE ROLE OF GRAMMATICAL GENDER IN COMPREHENDING A LINE DRAWING WITHIN A WRITTEN SENTENCE IN SPANISH

    PubMed Central

    Wicha, Nicole Y. Y.; Moreno, Eva M.; Kutas, Marta

    2012-01-01

    Event-related brain potentials (ERPs) were used to examine the role of grammatical gender in written sentence comprehension. Native Spanish speakers read sentences in which a drawing depicting a target noun was either congruent or incongruent with sentence meaning, and either agreed or disagreed in gender with that of the preceding article. The gender-agreement violation at the drawing was associated with an enhanced negativity between 500 and 700 msec post-stimulus onset. Semantically incongruent drawings elicited a larger N400 than congruent drawings regardless of gender (dis)agreement, indicating little effect of grammatical gender agreement on contextual integration of a picture into a written sentence context. We also observed an enhanced negativity for articles with unexpected relative to expected gender based on prior sentence context indicating that readers generate expectations for specific nouns and their articles. PMID:12870823

  4. Decoding gender dimorphism of the human brain using multimodal anatomical and diffusion MRI data.

    PubMed

    Feis, Delia-Lisa; Brodersen, Kay H; von Cramon, D Yves; Luders, Eileen; Tittgemeyer, Marc

    2013-04-15

    The female brain contains a larger proportion of gray matter tissue, while the male brain comprises more white matter. Findings like these have sparked increasing interest in studying dimorphism of the human brain: the general effect of gender on aspects of brain architecture. To date, the vast majority of imaging studies is based on unimodal MR images and typically limited to a small set of either gray or white matter regions-of-interest. The morphological content of magnetic resonance (MR) images, however, strongly depends on the underlying contrast mechanism. Consequently, in order to fully capture gender-specific morphological differences in distinct brain tissues, it might prove crucial to consider multiple imaging modalities simultaneously. This study introduces a novel approach to perform such multimodal classification incorporating the relative strengths of each modality-specific physical aperture to tissue properties. To illustrate our approach, we analyzed multimodal MR images (T(1)-, T(2)-, and diffusion-weighted) from 121 subjects (67 females) using a linear support vector machine with a mass-univariate feature selection procedure. We demonstrate that the combination of different imaging modalities yields a significantly higher balanced classification accuracy (96%) than any one modality by itself (83%-88%). Our results do not only confirm previous morphometric findings; crucially, they also shed new light on the most discriminative features in gray-matter volume and microstructure in cortical and subcortical areas. Specifically, we find that gender disparities are primarily distributed along brain networks thought to be involved in social cognition, reward-based learning, decision-making, and visual-spatial skills. PMID:23298750

  5. [Does the brain have a gender? A literature review in younger and older adults].

    PubMed

    Compère, Laurie; Piolino, Pascale

    2014-12-01

    There are no longer doubts about the existence of gender's differences in cognition, only their origin is still controversial. The literature provides evidence of differences in cognitive performance and brain activation patterns and links these differences in men and women with biological, social and psychological measures. To date, the favored hypothesis explaining these differences is the cognitive style hypothesis according to which women and men would favor different strategies while resolving some tasks. Some of these tasks are autobiographical memory tasks, which are also the most sensitive to the effects of age but very few studies had explored the impact of aging on the differences in cognition between men and women. We discuss the importance of such studies about the gender's differences in aging. A better understanding of gender differences in cognition in pathological aging as in health would provide the opportunity to offer a more personalized care. PMID:25515905

  6. Brain Decoding-Classification of Hand Written Digits from fMRI Data Employing Bayesian Networks.

    PubMed

    Yargholi, Elahe'; Hossein-Zadeh, Gholam-Ali

    2016-01-01

    We are frequently exposed to hand written digits 0-9 in today's modern life. Success in decoding-classification of hand written digits helps us understand the corresponding brain mechanisms and processes and assists seriously in designing more efficient brain-computer interfaces. However, all digits belong to the same semantic category and similarity in appearance of hand written digits makes this decoding-classification a challenging problem. In present study, for the first time, augmented naïve Bayes classifier is used for classification of functional Magnetic Resonance Imaging (fMRI) measurements to decode the hand written digits which took advantage of brain connectivity information in decoding-classification. fMRI was recorded from three healthy participants, with an age range of 25-30. Results in different brain lobes (frontal, occipital, parietal, and temporal) show that utilizing connectivity information significantly improves decoding-classification and capability of different brain lobes in decoding-classification of hand written digits were compared to each other. In addition, in each lobe the most contributing areas and brain connectivities were determined and connectivities with short distances between their endpoints were recognized to be more efficient. Moreover, data driven method was applied to investigate the similarity of brain areas in responding to stimuli and this revealed both similarly active areas and active mechanisms during this experiment. Interesting finding was that during the experiment of watching hand written digits, there were some active networks (visual, working memory, motor, and language processing), but the most relevant one to the task was language processing network according to the voxel selection. PMID:27468261

  7. Adolescent Binge Drinking Linked to Abnormal Spatial Working Memory Brain Activation: Differential Gender Effects

    PubMed Central

    Squeglia, Lindsay M.; Schweinsburg, Alecia Dager; Pulido, Carmen; Tapert, Susan F.

    2011-01-01

    Background Binge drinking is prevalent during adolescence, and its effect on neurocognitive development is of concern. In adult and adolescent populations, heavy substance use has been associated with decrements in cognitive functioning, particularly on tasks of spatial working memory (SWM). Characterizing the gender-specific influences of heavy episodic drinking on SWM may help elucidate the early functional consequences of drinking on adolescent brain functioning. Methods 40 binge drinkers (13 females, 27 males) and 55 controls (24 females, 31 males) ages 16 to 19, completed neuropsychological testing, substance use interviews, and a spatial working memory task (SWM) during functional magnetic resonance imaging (fMRI). Results Significant binge drinking status x gender interactions were found (p<.05) in 8 brain regions spanning bilateral frontal, anterior cingulate, temporal, and cerebellar cortices. In all regions, female binge drinkers showed less SWM activation than female controls, while male bingers exhibited greater SWM response than male controls. For female binge drinkers, less activation was associated with poorer sustained attention and working memory performances (ps<.025). For male binge drinkers, greater activation was linked to better spatial performance (p<.025). Conclusion Binge drinking during adolescence is associated with gender-specific differences in frontal, temporal, and cerebellar brain activation during a SWM task, which in turn relate to cognitive performance. Activation correlates with neuropsychological performance, strengthening the argument that BOLD activation is both affected by alcohol use and is an important indicator of behavioral functioning. Females may be more vulnerable to the neurotoxic effects of heavy alcohol use during adolescence, while males may be more resilient to the deleterious effects of binge drinking. Future longitudinal research will examine the significance of SWM brain activation as an early neurocognitive

  8. Gender Differences in Awareness and Outcomes During Acute Traumatic Brain Injury Recovery

    PubMed Central

    Perrin, Paul B.; Holcomb, Megan G.; Rolston, Cynthia D.; Artman, Laura K.; Lu, Juan; Nersessova, Karine S.

    2014-01-01

    Abstract Background: Recent literature on traumatic brain injury (TBI), though mixed when reporting outcomes, seems collectively to suggest possible gender advantage for women in postinjury recovery, especially in executive functions. Hormonal neuroprotection, through female reproductive hormones, is often proposed as an underlying factor in these results. We explored potential gender differences in an aspect of executive functions, self-awareness (SA), which is often impaired after TBI, limits patient effort in critical rehabilitation, and increases caregiver burden. Methods: Within a prospective survey, repeated-measures design, 121 patients with moderate or severe TBI undergoing acute rehabilitation in a Level 1 trauma center, a family member or caregiver informant, and a treating clinician were asked to complete the Patient Competency Rating Scale (PCRS) and the Frontal Systems Behavior Scale (FrSBe) at admission and discharge. Results: Although overall, women and men with TBI showed generally similar levels of SA, women had significantly better awareness of their injury-related deficits at acute rehabilitation discharge, even when controlling for age, education, and injury severity. Conclusions: Mixed findings in this study mirror the pattern of results that dominate the published literature on gender and TBI. Gender differences in executive dysfunction may not be as large or robust as some researchers argue. In addition, complex interplays of socialization, gender-role expectations, naturally occurring male and female ability differences, and differences in access to postinjury rehabilitation are understudied potential moderators. PMID:24932911

  9. Does Performance in Digital Reading Relate to Computer Game Playing? A Study of Factor Structure and Gender Patterns in 15-Year-Olds' Reading Literacy Performance

    ERIC Educational Resources Information Center

    Rasmusson, Maria; Åberg-Bengtsson, Lisbeth

    2015-01-01

    Data from a Swedish PISA-sample were used (1) to identify a digital reading factor, (2) to investigate gender differences in this factor (if found), and (3) to explore how computer game playing might relate to digital reading performance and gender. The analyses were conducted with structural equation modeling techniques. In addition to an overall…

  10. Brain Decoding-Classification of Hand Written Digits from fMRI Data Employing Bayesian Networks

    PubMed Central

    Yargholi, Elahe'; Hossein-Zadeh, Gholam-Ali

    2016-01-01

    We are frequently exposed to hand written digits 0–9 in today's modern life. Success in decoding-classification of hand written digits helps us understand the corresponding brain mechanisms and processes and assists seriously in designing more efficient brain–computer interfaces. However, all digits belong to the same semantic category and similarity in appearance of hand written digits makes this decoding-classification a challenging problem. In present study, for the first time, augmented naïve Bayes classifier is used for classification of functional Magnetic Resonance Imaging (fMRI) measurements to decode the hand written digits which took advantage of brain connectivity information in decoding-classification. fMRI was recorded from three healthy participants, with an age range of 25–30. Results in different brain lobes (frontal, occipital, parietal, and temporal) show that utilizing connectivity information significantly improves decoding-classification and capability of different brain lobes in decoding-classification of hand written digits were compared to each other. In addition, in each lobe the most contributing areas and brain connectivities were determined and connectivities with short distances between their endpoints were recognized to be more efficient. Moreover, data driven method was applied to investigate the similarity of brain areas in responding to stimuli and this revealed both similarly active areas and active mechanisms during this experiment. Interesting finding was that during the experiment of watching hand written digits, there were some active networks (visual, working memory, motor, and language processing), but the most relevant one to the task was language processing network according to the voxel selection. PMID:27468261

  11. Regional volumes and spatial volumetric distribution of gray matter in the gender dysphoric brain.

    PubMed

    Hoekzema, Elseline; Schagen, Sebastian E E; Kreukels, Baudewijntje P C; Veltman, Dick J; Cohen-Kettenis, Peggy T; Delemarre-van de Waal, Henriette; Bakker, Julie

    2015-05-01

    The sexual differentiation of the brain is primarily driven by gonadal hormones during fetal development. Leading theories on the etiology of gender dysphoria (GD) involve deviations herein. To examine whether there are signs of a sex-atypical brain development in GD, we quantified regional neural gray matter (GM) volumes in 55 female-to-male and 38 male-to-female adolescents, 44 boys and 52 girls without GD and applied both univariate and multivariate analyses. In girls, more GM volume was observed in the left superior medial frontal cortex, while boys had more volume in the bilateral superior posterior hemispheres of the cerebellum and the hypothalamus. Regarding the GD groups, at whole-brain level they differed only from individuals sharing their gender identity but not from their natal sex. Accordingly, using multivariate pattern recognition analyses, the GD groups could more accurately be automatically discriminated from individuals sharing their gender identity than those sharing their natal sex based on spatially distributed GM patterns. However, region of interest analyses indicated less GM volume in the right cerebellum and more volume in the medial frontal cortex in female-to-males in comparison to girls without GD, while male-to-females had less volume in the bilateral cerebellum and hypothalamus than natal boys. Deviations from the natal sex within sexually dimorphic structures were also observed in the untreated subsamples. Our findings thus indicate that GM distribution and regional volumes in GD adolescents are largely in accordance with their respective natal sex. However, there are subtle deviations from the natal sex in sexually dimorphic structures, which can represent signs of a partial sex-atypical differentiation of the brain. PMID:25720349

  12. Gender Differences in the Effect of Tobacco Use on Brain Phosphocreatine Levels in Methamphetamine Dependent Subjects

    PubMed Central

    Sung, Young-Hoon; Yurgelun-Todd, Deborah A.; Kondo, Douglas G.; Shi, Xian-Feng; Lundberg, Kelly J.; Hellem, Tracy L.; Huber, Rebekah S.; McGlade, Erin C.; Jeong, Eun-Kee; Renshaw, Perry F.

    2015-01-01

    Background A high prevalence of tobacco smoking has been observed in methamphetamine users, but there have been no in vivo brain neurochemistry studies addressing gender effects of tobacco smoking in methamphetamine users. Methamphetamine addiction is associated with increased risk of depression and anxiety in females. There is increasing evidence that selective analogues of nicotine, a principal active component of tobacco smoking, may improve depression and cognitive performance in animals and humans. Objectives To investigate the effects of tobacco smoking and gender on brain phosphocreatine (PCr) levels, a marker of brain energy metabolism reported to be reduced in methamphetamine-dependent subjects. Methods Thirty female and twenty-seven male methamphetamine-dependent subjects were evaluated with phosphorus-31 magnetic resonance spectroscopy (31P-MRS) to measure PCr levels within the pregenual anterior cingulate, which has been implicated in methamphetamine neurotoxicity. Results Analysis of covariance revealed that there were statistically significant slope (PCr versus lifetime amount of tobacco smoking) differences between female and male methamphetamine-dependent subjects (p=0.03). In females, there was also a statistically significant interaction between lifetime amounts of tobacco smoking and methamphetamine in regard to PCr levels (p=0.01), which suggests that tobacco smoking may have a more significant positive impact on brain PCr levels in heavy, as opposed to light to moderate, methamphetamine-dependent females. Conclusion These results indicate that tobacco smoking has gender-specific effects in terms of increased anterior cingulate high energy PCr levels in methamphetamine-dependent subjects. Cigarette smoking in methamphetamine-dependent women, particularly those with heavy methamphetamine use, may have a potentially protective effect upon neuronal metabolism. PMID:25871447

  13. The Influence of Gender Difference on the Information-Seeking Behaviors for the Graphical Interface of Children's Digital Library

    ERIC Educational Resources Information Center

    Hsieh, Tsia-ying; Wu, Ko-chiu

    2015-01-01

    Children conducting searches using the interfaces of library websites often encounter obstacles due to typographical errors, digital divides, or a failure to grasp keywords. Satisfaction with a given interface may also vary according to the gender of the user, making it a variable in information seeking behavior. Children benefit more from…

  14. Gender Differences in Neurological Emergencies Part II: A Consensus Summary and Research Agenda on Traumatic Brain Injury

    PubMed Central

    Wright, David W.; Espinoza, Tamara R.; Merck, Lisa H.; Ratcliff, Jonathan J.; Backster, Anika; Stein, Donald G.

    2015-01-01

    Traumatic brain injury (TBI) is a major cause of death and disability worldwide. There is strong evidence that gender and sex play an important role across the spectrum of TBI, from pathophysiology to clinical care. In May 2014, Academic Emergency Medicine held a consensus conference “Gender-Specific Research in Emergency Care: Investigate, Understand, and Translate How Gender Affects Patient Outcomes.” A TBI working group was formed to explore what was known about the influence of sex and gender on TBI and to identify gaps for future research. The findings resulted in four major recommendations to guide the TBI research agenda. PMID:25420582

  15. Gender differences in neurological emergencies part II: a consensus summary and research agenda on traumatic brain injury.

    PubMed

    Wright, David W; Espinoza, Tamara R; Merck, Lisa H; Ratcliff, Jonathan J; Backster, Anika; Stein, Donald G

    2014-12-01

    Traumatic brain injury (TBI) is a major cause of death and disability worldwide. There is strong evidence that gender and sex play an important role across the spectrum of TBI, from pathophysiology to clinical care. In May 2014, Academic Emergency Medicine held a consensus conference "Gender-Specific Research in Emergency Care: Investigate, Understand, and Translate How Gender Affects Patient Outcomes." A TBI working group was formed to explore what was known about the influence of sex and gender on TBI and to identify gaps for future research. The findings resulted in four major recommendations to guide the TBI research agenda. PMID:25420582

  16. Gender differences in brain development in Chinese children and adolescents: a structural MRI study

    NASA Astrophysics Data System (ADS)

    Guo, Xiaojuan; Jin, Zhen; Chen, Kewei; Peng, Danling; Yao, Li

    2008-03-01

    Using optimized voxel-based morphometry (VBM), this study systematically investigated gender differences in brain development through magnetic resonance imaging (MRI) data in 158 Chinese normal children and adolescents aged 7.26 to 22.80 years (mean age 15.03+/-4.70 years, 78 boys and 80 girls). Gender groups were matched for measures of age, handedness, education level. The customized brain templates, including T I-weighted image and gray matter (GM)/white matter (WM)/cerebro-spinal fluid (CSF) prior probability maps, were created from all participants. Results showed that the total intracranial volume (TIV), global absolute GM and global WM volume in girls were significantly smaller than those in boys. The hippocampus grew faster in girls than that in boys, but the amygdala grew faster in boys than that in girls. The rate of regional GM decreases with age was steeper in the left superior parietal lobule, bilateral inferior parietal lobule, left precuneus, and bilateral supramarginal gyrus in boys compared to girls, which was possibly related to better spatial processing ability in boys. Regional GM volumes were greater in bilateral superior temporal gyrus, bilateral inferior frontal gyrus and bilateral middle frontal gyrus in girls. Regional WM volumes were greater in the left temporal lobe, right inferior parietal and bilateral middle frontal gyrus in girls. The gender differences in the temporal and frontal lobe maybe be related to better language ability in girls. These findings may aid in understanding the differences in cognitive function between boys and girls.

  17. Gender-Associated Differential Expression of Cytokines in Specific Areas of the Brain During Helminth Infection

    PubMed Central

    López-Griego, Lorena; Nava-Castro, Karen Elizabeth; López-Salazar, Valeria; Hernández-Cervantes, Rosalía; Tiempos Guzmán, Nelly; Muñiz-Hernández, Saé; Hernández-Bello, Romel; Besedovsky, Hugo O.; Pavón, Lenin; Becerril Villanueva, Luis Enrique

    2015-01-01

    Intraperitoneal infection with Taenia crassiceps cysticerci in mice alters several behaviors, including sexual, aggressive, and cognitive function. Cytokines and their receptors are produced in the central nervous system (CNS) by specific neural cell lineages under physiological and pathological conditions, regulating such processes as neurotransmission. This study is aimed to determine the expression patterns of cytokines in various areas of the brain in normal and T. crassiceps-infected mice in both genders and correlate them with the pathology of the CNS and parasite counts. IL-4, IFN-γ, and TNF-α levels in the hippocampus and olfactory bulb increased significantly in infected male mice, but IL-6 was downregulated in these regions in female mice. IL-1β expression in the hippocampus was unaffected by infection in either gender. Our novel findings demonstrate a clear gender-associated pattern of cytokine expression in specific areas of the brain in mammals that parasitic infection can alter. Thus, we hypothesize that intraperitoneal infection is sensed by the CNS of the host, wherein cytokines are important messengers in the host–parasite neuroimmunoendocrine network. PMID:25495255

  18. Gender Differences of Brain Activity in the Conflicts Based on Implicit Self-Esteem

    PubMed Central

    Miyamoto, Reiko; Kikuchi, Yoshiaki

    2012-01-01

    There are gender differences in global and domain-specific self-esteem and the incidence of some psychiatric disorders related to self-esteem, suggesting that there are gender differences in the neural basis underlying one's own self-esteem. We investigated gender differences in the brain activity while subjects (14 males and 12 females) performed an implicit self-esteem task, using fMRI. While ventromedial prefrontal cortex (vmPFC) was significantly activated in females, medial and dorsomedial PFC (dmPFC) were activated in males in the incongruent condition (self = negative) compared with the congruent condition (self = positive). Additionally, scores on the explicit self-esteem test were negatively correlated with vmPFC activity in females and positively correlated with dmPFC activity in males. Furthermore, the functional relationships among the regions found by direct gender comparisons were discussed based on the somatic-marker model. These showed that, compared to males, females more firmly store even the incongruent associations as part of their schematic self-knowledge, and such associations automatically activate the neural networks for emotional response and control, in which vmPFC plays a central role. This may explain female cognitive/behavioral traits; females have more tendency to ruminate more often than males, which sometimes results in a prolonged negative affect. PMID:22666409

  19. Why mental arithmetic counts: brain activation during single digit arithmetic predicts high school math scores.

    PubMed

    Price, Gavin R; Mazzocco, Michèle M M; Ansari, Daniel

    2013-01-01

    Do individual differences in the brain mechanisms for arithmetic underlie variability in high school mathematical competence? Using functional magnetic resonance imaging, we correlated brain responses to single digit calculation with standard scores on the Preliminary Scholastic Aptitude Test (PSAT) math subtest in high school seniors. PSAT math scores, while controlling for PSAT Critical Reading scores, correlated positively with calculation activation in the left supramarginal gyrus and bilateral anterior cingulate cortex, brain regions known to be engaged during arithmetic fact retrieval. At the same time, greater activation in the right intraparietal sulcus during calculation, a region established to be involved in numerical quantity processing, was related to lower PSAT math scores. These data reveal that the relative engagement of brain mechanisms associated with procedural versus memory-based calculation of single-digit arithmetic problems is related to high school level mathematical competence, highlighting the fundamental role that mental arithmetic fluency plays in the acquisition of higher-level mathematical competence. PMID:23283330

  20. A three-dimensional digital atlas of the starling brain.

    PubMed

    De Groof, Geert; George, Isabelle; Touj, Sara; Stacho, Martin; Jonckers, Elisabeth; Cousillas, Hugo; Hausberger, Martine; Güntürkün, Onur; Van der Linden, Annemie

    2016-05-01

    Because of their sophisticated vocal behaviour, their social nature, their high plasticity and their robustness, starlings have become an important model species that is widely used in studies of neuroethology of song production and perception. Since magnetic resonance imaging (MRI) represents an increasingly relevant tool for comparative neuroscience, a 3D MRI-based atlas of the starling brain becomes essential. Using multiple imaging protocols we delineated several sensory systems as well as the song control system. This starling brain atlas can easily be used to determine the stereotactic location of identified neural structures at any angle of the head. Additionally, the atlas is useful to find the optimal angle of sectioning for slice experiments, stereotactic injections and electrophysiological recordings. The starling brain atlas is freely available for the scientific community. PMID:25690327

  1. WAIS Digit Span-Based Indicators of Malingered Neurocognitive Dysfunction: Classification Accuracy in Traumatic Brain Injury

    ERIC Educational Resources Information Center

    Heinly, Matthew T.; Greve, Kevin W.; Bianchini, Kevin J.; Love, Jeffrey M.; Brennan, Adrianne

    2005-01-01

    The present study determined specificity and sensitivity to malingered neurocognitive dysfunction (MND) in traumatic brain injury (TBI) for several Wechsler Adult Intelligence Scale (WAIS) Digit Span scores. TBI patients (n = 344) were categorized into one of five groups: no incentive, incentive only, suspect, probable MND, and definite MND.…

  2. Sex/gender differences in the brain and cognition in schizophrenia.

    PubMed

    Mendrek, Adrianna; Mancini-Marïe, Adham

    2016-08-01

    The early conceptualizations of schizophrenia have noted some sex/gender differences in epidemiology and clinical expression of the disorder. Over the past few decades, the interest in differences between male and female patients has expanded to encompass brain morphology and neurocognitive function. Despite some variability and methodological shortcomings, a few patterns emerge from the available literature. Most studies of gross neuroanatomy show more enlarged ventricles and smaller frontal lobes in men than in women with schizophrenia; finding reflecting normal sexual dimorphism. In comparison, studies of brain asymmetry and specific corticolimbic structures, suggest a disturbance in normal sexual dimorphism. The neurocognitive findings are somewhat consistent with this picture. Studies of cognitive functions mediated by the lateral frontal network tend to show sex differences in patients which are in the same direction as those observed in the general population, whereas studies of processes mediated by the corticolimbic system more frequently reveal reversal of normal sexual dimorphisms. These trends are faint and future research would need to delineate neurocognitive differences between men and women with various subtypes of schizophrenia (e.g., early versus late onset), while taking into consideration hormonal status and gender of tested participants. PMID:26743859

  3. Gender Influences on Brain Responses to Errors and Post-Error Adjustments

    PubMed Central

    Fischer, Adrian G.; Danielmeier, Claudia; Villringer, Arno; Klein, Tilmann A.; Ullsperger, Markus

    2016-01-01

    Sexual dimorphisms have been observed in many species, including humans, and extend to the prevalence and presentation of important mental disorders associated with performance monitoring malfunctions. However, precisely which underlying differences between genders contribute to the alterations observed in psychiatric diseases is unknown. Here, we compare behavioural and neural correlates of cognitive control functions in 438 female and 436 male participants performing a flanker task while EEG was recorded. We found that males showed stronger performance-monitoring-related EEG amplitude modulations which were employed to predict subjects’ genders with ~72% accuracy. Females showed more post-error slowing, but both samples did not differ in regard to response-conflict processing and coupling between the error-related negativity (ERN) and consecutive behavioural slowing. Furthermore, we found that the ERN predicted consecutive behavioural slowing within subjects, whereas its overall amplitude did not correlate with post-error slowing across participants. These findings elucidate specific gender differences in essential neurocognitive functions with implications for clinical studies. They highlight that within- and between-subject associations for brain potentials cannot be interpreted in the same way. Specifically, despite higher general amplitudes in males, it appears that the dynamics of coupling between ERN and post-error slowing between men and women is comparable. PMID:27075509

  4. Police culture influences the brain function underlying compassion: a gender study.

    PubMed

    Mercadillo, Roberto E; Alcauter, Sarael; Fernández-Ruiz, Juan; Barrios, Fernando A

    2015-04-01

    Compassion is a prototypical moral emotion supporting cooperation and involves empathic decision-making and motor processes representing the interplay of biologically evolved and cultural mechanisms. We propose a social neuroscience approach to identify gender differences and to assess biological and cultural factors shaping compassion. We consider the police force as a cultural model to study this emotion, because it comprises a mixed-gender group using specific codes for collective safety that influence empathy and cooperativeness. From a sample of Mexican police officers working in a violent environment we integrated ethnographic data categorizing compassionate elements in the officers' activities, psychometric measures evaluating empathic attitudes, and fMRI scans identifying the brain activity related to compassionate experiences and decisions. The results suggest that the police culture influences genders equally with respect to empathic behavioral expressions. Nevertheless, women showed insular and prefrontal cortical activation, suggesting a more empathic experience of compassion. Officers manifested activity in the caudate nucleus, amygdala, and cerebellum, suggesting a more a highly accurate process to infer another's suffering and a reward system motivated by the notion of service and cooperation, both of which are cultural traits represented in the police force. PMID:25372925

  5. Patterns of Behavioral Deficits in Rodents Following Brain Injury Across Species, Gender, and Experimental Model.

    PubMed

    Hartman, Richard E; Thorndyke, Earl C

    2016-01-01

    Behavioral data were collected from several hundred mice and rats using a variety of experimental models of brain injury. The use of consistent protocols allowed compilation of these data, facilitating analyses of animal behaviors across experimental models, species, and gender. Spatial learning and sensorimotor/coordination data are presented, suggesting that, in general, rats performed better than mice both in the water maze and on the rotarod. Compared with females, males performed slightly better in the water maze and slightly worse on the rotarod. However, gender by species interactions accounted for both of these differences. Male rats performed better in the water maze than female rats, male mice, and female mice, which did not differ. Male mice performed worse on the rotarod than female mice, male rats, and female rats, which performed similarly. Furthermore, animals with subcortical injury were impaired in the water maze, but performed better than animals with cortical injuries. However, only animals with cortical injuries were impaired on the rotarod. Additional covariates, such as edema and lesion size, may further clarify these phenotypes. Overall, we provide evidence that abbreviated test batteries can be specifically designed to test deficits, depending on the species, gender, and model. PMID:26463925

  6. Digital Atlas of the Zebra Finch (Taeniopygia guttata) Brain: a High Resolution Photo Atlas

    PubMed Central

    Karten, Harvey J.; Brzozowska-Prechtl, Agnieszka; Lovell, Peter V.; Tang, Daniel D.; Mello, Claudio V.; Wang, Haibin; Mitra, Partha P.

    2014-01-01

    We describe a set of new comprehensive, high-quality, high-resolution digital images of histological sections from the brain of male zebra finches (Taeniopygia guttata), and make them publicly available through an interactive website (http://zebrafinch.brainarchitecture.org/). These images provide a basis for the production of a dimensionally accurate and detailed digital non-stereotaxic atlas. Nissl- and myelin-stained brain sections are provided in the transverse, sagittal, and horizontal planes, with the transverse plane approximating the more traditional Frankfurt Plane. In addition, a separate set of brain sections in this same plane is stained for tyrosine hydroxylase, revealing the distribution of catecholaminergic neurons (dopaminergic, noradrenergic, and adrenergic) in the songbird brain. For a subset of sagittal sections we have also prepared a corresponding set of drawings, defining and annotating various nuclei, fields, and fiber tracts that are visible under Nissl and myelin staining. This atlas of the zebra finch brain is expected to become an important tool for birdsong research and comparative studies of brain organization and evolution. PMID:23896990

  7. Protein carbonylation after traumatic brain injury: cell specificity, regional susceptibility, and gender differences.

    PubMed

    Lazarus, Rachel C; Buonora, John E; Jacobowitz, David M; Mueller, Gregory P

    2015-01-01

    Protein carbonylation is a well-documented and quantifiable consequence of oxidative stress in several neuropathologies, including multiple sclerosis, Alzheimer׳s disease, and Parkinson׳s disease. Although oxidative stress is a hallmark of traumatic brain injury (TBI), little work has explored the specific neural regions and cell types in which protein carbonylation occurs. Furthermore, the effect of gender on protein carbonylation after TBI has not been studied. The present investigation was designed to determine the regional and cell specificity of TBI-induced protein carbonylation and how this response to injury is affected by gender. Immunohistochemistry was used to visualize protein carbonylation in the brains of adult male and female Sprague-Dawley rats subjected to controlled cortical impact (CCI) as an injury model of TBI. Cell-specific markers were used to colocalize the presence of carbonylated proteins in specific cell types, including astrocytes, neurons, microglia, and oligodendrocytes. Results also indicated that the injury lesion site, ventral portion of the dorsal third ventricle, and ventricular lining above the median eminence showed dramatic increases in protein carbonylation after injury. Specifically, astrocytes and limited regions of ependymal cells adjacent to the dorsal third ventricle and the median eminence were most susceptible to postinjury protein carbonylation. However, these patterns of differential susceptibility to protein carbonylation were gender dependent, with males showing significantly greater protein carbonylation at sites distant from the lesion. Proteomic analyses were also conducted and determined that the proteins most affected by carbonylation in response to TBI include glial fibrillary acidic protein, dihydropyrimidase-related protein 2, fructose-bisphosphate aldolase C, and fructose-bisphosphate aldolase A. Many other proteins, however, were not carbonylated by CCI. These findings indicate that there is both regional

  8. Effects of ractopamine feeding, gender and social rank on aggressiveness and monoamine concentrations in different brain areas of finishing pigs

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This study evaluated the effects of the feed additive ractopamine (RAC), gender and social rank on aggressiveness and brain monoamines levels of serotonin (5HT), dopamine (DA), their metabolites, norepinephrine (NE) and epinephrine (EP) in finishing pigs. Thirty-two pigs (16 barrows/16 gilts) were a...

  9. Response of face-selective brain regions to trustworthiness and gender of faces.

    PubMed

    Mattavelli, Giulia; Andrews, Timothy J; Asghar, Aziz U R; Towler, John R; Young, Andrew W

    2012-07-01

    Neuropsychological and neuroimaging studies have demonstrated a role for the amygdala in processing the perceived trustworthiness of faces, but it remains uncertain whether its responses are linear (with the greatest response to the least trustworthy-looking faces), or quadratic (with increased fMRI signal for the dimension extremes). It is also unclear whether the trustworthiness of the stimuli is crucial or if the same response pattern can be found for faces varying along other dimensions. In addition, the responses to perceived trustworthiness of face-selective regions other than the amygdala are seldom reported. The present study addressed these issues using a novel set of stimuli created through computer image-manipulation both to maximise the presence of naturally occurring cues that underpin trustworthiness judgments and to allow systematic manipulation of these cues. With a block-design fMRI paradigm, we investigated neural responses to computer-manipulated trustworthiness in the amygdala and core face-selective regions in the occipital and temporal lobes. We asked whether the activation pattern is specific for differences in trustworthiness or whether it would also track variation along an orthogonal male-female gender dimension. The main findings were quadratic responses to changes in both trustworthiness and gender in all regions. These results are consistent with the idea that face-responsive brain regions are sensitive to face distinctiveness as well as the social meaning of the face features. PMID:22659107

  10. Synchronous brain activity during cooperative exchange depends on gender of partner: A fNIRS-based hyperscanning study.

    PubMed

    Cheng, Xiaojun; Li, Xianchun; Hu, Yi

    2015-06-01

    Previous studies have shown that brain activity between partners is synchronized during cooperative exchange. Whether this neural synchronization depends on the gender of partner (i.e., opposite or same to the participant) is open to be explored. In current study, we used functional near-infrared spectroscopy (fNIRS) based hyperscanning to study cooperation in a two-person game (female-female, female-male, and male-male) while assaying brain-to-brain interactions. Cooperation was greater in male-male pairs than in female-female pairs, with intermediate cooperation levels for female-male pairs. More importantly, in dyads with partners with opposite gender (female-male pairs), we found significant task-related cross-brain coherence in frontal regions (i.e., frontopolar cortex, orbitofrontal cortex, and left dorsolateral prefrontal cortex) whereas the cooperation in same gender dyads (female-female pairs and male-male pairs) was not associated with such synchronization. Moreover, the changes of such interbrain coherence across task blocks were significantly correlated with change in degree of cooperation only in mixed-sex dyads. These findings suggested that different neural processes underlie cooperation between mixed-sex and same-sex dyadic interactions. PMID:25691124

  11. A Critical Review of the Research on the Extreme Male Brain Theory and Digit Ratio (2D:4D)

    ERIC Educational Resources Information Center

    Teatero, Missy L.; Netley, Charles

    2013-01-01

    Boys are more likely than girls to be diagnosed with an autism spectrum disorder (ASD). The extreme male brain (EMB) theory of ASD suggests that fetal testosterone (FT) exposure may underlie sex differences in autistic traits. A link between the organizational effects of FT on the brain and ASD is often drawn based on research using digit ratio…

  12. Development of a realistic, dynamic digital brain phantom for CT perfusion validation

    NASA Astrophysics Data System (ADS)

    Divel, Sarah E.; Segars, W. Paul; Christensen, Soren; Wintermark, Max; Lansberg, Maarten G.; Pelc, Norbert J.

    2016-03-01

    Physicians rely on CT Perfusion (CTP) images and quantitative image data, including cerebral blood flow, cerebral blood volume, and bolus arrival delay, to diagnose and treat stroke patients. However, the quantification of these metrics may vary depending on the computational method used. Therefore, we have developed a dynamic and realistic digital brain phantom upon which CTP scans can be simulated based on a set of ground truth scenarios. Building upon the previously developed 4D extended cardiac-torso (XCAT) phantom containing a highly detailed brain model, this work consisted of expanding the intricate vasculature by semi-automatically segmenting existing MRA data and fitting nonuniform rational B-spline surfaces to the new vessels. Using time attenuation curves input by the user as reference, the contrast enhancement in the vessels changes dynamically. At each time point, the iodine concentration in the arteries and veins is calculated from the curves and the material composition of the blood changes to reflect the expected values. CatSim, a CT system simulator, generates simulated data sets of this dynamic digital phantom which can be further analyzed to validate CTP studies and post-processing methods. The development of this dynamic and realistic digital phantom provides a valuable resource with which current uncertainties and controversies surrounding the quantitative computations generated from CTP data can be examined and resolved.

  13. Gender, intoxication and the developing brain: Problematisations of drinking among young adults in Australian alcohol policy.

    PubMed

    Manton, Elizabeth; Moore, David

    2016-05-01

    In this article, we draw on recent scholarly work in the poststructuralist analysis of policy to consider how policy itself functions as a key site in the constitution of alcohol 'problems', and the political implications of these problematisations. We do this by examining Australian alcohol policy as it relates to young adults (18-24 years old). Our critical analysis focuses on three national alcohol policies (1990, 2001 and 2006) and two Victorian state alcohol policies (2008 and 2013), which together span a 25-year period. We argue that Australian alcohol policies have conspicuously ignored young adult men, despite their ongoing over-representation in the statistical 'evidence base' on alcohol-related harm, while increasingly problematising alcohol consumption amongst other population subgroups. We also identify the development of a new problem representation in Australian alcohol policy, that of 'intoxication' as the leading cause of alcohol-related harm and rising hospital admissions, and argue that changes in the classification and diagnosis of intoxication may have contributed to its prioritisation and problematisation in alcohol policy at the expense of other forms of harm. Finally, we draw attention to how preliminary and inconclusive research on the purported association between binge drinking and brain development in those under 25 years old has been mobilised prematurely to support calls to increase the legal purchasing age from 18 to 21 years. Our critical analysis of the treatment of these three issues - gender, intoxication, and brain development - is intended to highlight the ways in which policy functions as a key site in the constitution of alcohol 'problems'. PMID:26644026

  14. Challenging the other: exploring the role of opponent gender in digital game competition for female players.

    PubMed

    Vermeulen, Lotte; Núñez Castellar, Elena; Van Looy, Jan

    2014-05-01

    Abstract The present study investigated the effect of opponent gender on the game experience of female players. Concretely, it looked into skill perception and player emotions of women in same gender and cross-gender game competition. We set up a 2×2×2 (male vs. female opponent×low vs. high competitive women×lost vs. won game) experimental design in which women were instructed to play against a proclaimed male and female competitor. Unknowingly, however, participants played against an AI, which was configured to produce a winning and a losing condition for each opponent by manipulating difficulty. Results indicated that opponent gender only had an effect on perceived stress, which was higher with male opponents. Moreover, players evaluated their own gaming skills as lower and the skills of presumed male opponents as higher when they thought they were playing against men. Importantly, our results also showed that the above described pattern for self-perceived skills and perceived opponent skills was modulated by trait competitiveness with a larger effect size for low competitive women. Overall, this study illustrates that gender dynamics affect the play experience of women in cross-gender gaming competition. Implications and suggestions for future research are discussed. PMID:24724802

  15. A Digital Divide? Class and Gender in the Computer Practices of Two Mexicano Families.

    ERIC Educational Resources Information Center

    Menard-Warwick, Julia; Dabach, Dafney Blanca

    The purpose of this paper is to critically re-examine the popular concept of a developing "digital divide." Based on qualitative studies of the computer practices of two Mexicano families resident in California, the paper argues with Warschauer (2001) that the "digital divide" should be seen as a continuum of varying degrees of engagement with…

  16. Effects of Gender Differences and Spatial Abilities within a Digital Pentominoes Game

    ERIC Educational Resources Information Center

    Yang, Jie Chi; Chen, Sherry Y.

    2010-01-01

    Spatial ability is a critical skill in geometric learning. Several studies investigate how to use digital games to improve spatial abilities. However, not every learner favors this kind of support. To this end, there is a need to examine how human factors affect learners' reactions to the use of a digital game to support geometric learning. In…

  17. NIR light propagation in a digital head model for traumatic brain injury (TBI)

    PubMed Central

    Francis, Robert; Khan, Bilal; Alexandrakis, George; Florence, James; MacFarlane, Duncan

    2015-01-01

    Near infrared spectroscopy (NIRS) is capable of detecting and monitoring acute changes in cerebral blood volume and oxygenation associated with traumatic brain injury (TBI). Wavelength selection, source-detector separation, optode density, and detector sensitivity are key design parameters that determine the imaging depth, chromophore separability, and, ultimately, clinical usefulness of a NIRS instrument. We present simulation results of NIR light propagation in a digital head model as it relates to the ability to detect intracranial hematomas and monitor the peri-hematomal tissue viability. These results inform NIRS instrument design specific to TBI diagnosis and monitoring. PMID:26417498

  18. NIR light propagation in a digital head model for traumatic brain injury (TBI).

    PubMed

    Francis, Robert; Khan, Bilal; Alexandrakis, George; Florence, James; MacFarlane, Duncan

    2015-09-01

    Near infrared spectroscopy (NIRS) is capable of detecting and monitoring acute changes in cerebral blood volume and oxygenation associated with traumatic brain injury (TBI). Wavelength selection, source-detector separation, optode density, and detector sensitivity are key design parameters that determine the imaging depth, chromophore separability, and, ultimately, clinical usefulness of a NIRS instrument. We present simulation results of NIR light propagation in a digital head model as it relates to the ability to detect intracranial hematomas and monitor the peri-hematomal tissue viability. These results inform NIRS instrument design specific to TBI diagnosis and monitoring. PMID:26417498

  19. GENDER DIFFERENCES IN BRAIN SUSCEPTIBILITY TO OXIDATIVE STRESS ARE MEDIATED BY LEVELS OF PARAOXONASE-2 (PON2) EXPRESSION

    PubMed Central

    Giordano, G.; Tait, L.; Furlong, C.E.; Cole, T.B.; Kavanagh, T.J.; Costa, L.G.

    2013-01-01

    Paraoxonase 2 (PON2), a member of a gene family that also includes PON1 and PON3, is expressed in most tissues, including the brain. In mouse brain, PON2 levels are highest in dopaminergic areas (e.g. striatum), and are higher in astrocytes than in neurons. PON2 is primarily located in mitochondria and exerts a potent antioxidant effect, protecting mouse CNS cells against oxidative stress. The aim of this study was to characterize PON2 expression and functions in the brains of male and female mice. Levels of PON2 (protein, mRNA, and lactonase activity) were higher in brain regions and cells of female mice. Astrocytes and neurons from male mice were significantly more sensitive (by 3–4-fold) to oxidative stress-induced toxicity than the same cells from female mice. Glutathione levels did not differ between genders. Importantly, no significant gender differences in susceptibility to the same oxidants were seen in cells from PON2−/− mice. Treatment with estradiol induced a time- and concentration-dependent increase in the levels of PON2 protein and mRNA in male (4.5-fold) and female (1.8-fold) astrocytes, which was dependent on activation of estrogen receptor alpha. In ovariectomized mice, PON2 protein and mRNA were decreased to male levels in brain regions and in liver. Estradiol protected astrocytes from wild-type mice against oxidative stress-induced neurotoxicity, but did not protect cells from PON2−/− mice. These results suggest that PON2 is a novel major intracellular factor that protects CNS cells against oxidative stress, and confers gender-dependent susceptibility to such stress. The lower expression of PON2 in males may have broad ramifications for susceptibility to diseases involving oxidative stress, including neurodegenerative diseases. PMID:23376469

  20. Twenty new digital brain phantoms for creation of validation image data bases.

    PubMed

    Aubert-Broche, Berengère; Griffin, Mark; Pike, G Bruce; Evans, Alan C; Collins, D Louis

    2006-11-01

    Simulations provide a way of generating data where ground truth is known, enabling quantitative testing of image processing methods. In this paper, we present the construction of 20 realistic digital brain phantoms that can be used to simulate medical imaging data. The phantoms are made from 20 normal adults to take into account intersubject anatomical variabilities. Each digital brain phantom was created by registering and averaging four T1, T2, and proton density (PD)-weighted magnetic resonance imaging (MRI) scans from each subject. A fuzzy minimum distance classification was used to classify voxel intensities from T1, T2, and PD average volumes into grey-matter, white matter, cerebro-spinal fluid, and fat. Automatically generated mask volumes were required to separate brain from nonbrain structures and ten fuzzy tissue volumes were created: grey matter, white matter, cerebro-spinal fluid, skull, marrow within the bone, dura, fat, tissue around the fat, muscles, and skin/muscles. A fuzzy vessel class was also obtained from the segmentation of the magnetic resonance angiography scan of the subject. These eleven fuzzy volumes that describe the spatial distribution of anatomical tissues define the digital phantom, where voxel intensity is proportional to the fraction of tissue within the voxel. These fuzzy volumes can be used to drive simulators for different modalities including MRI, PET, or SPECT. These phantoms were used to construct 20 simulated T1-weighted MR scans. To evaluate the realism of these simulations, we propose two approaches to compare them to real data acquired with the same acquisition parameters. The first approach consists of comparing the intensities within the segmented classes in both real and simulated data. In the second approach, a whole brain voxel-wise comparison between simulations and real T1-weighted data is performed. The first comparison underlines that segmented classes appear to properly represent the anatomy on average, and that

  1. Girl Power in a Digital World: Considering the Complexity of Gender, Literacy, and Technology

    ERIC Educational Resources Information Center

    Williams, Bronwyn T.

    2006-01-01

    The power of culture to shape gender identities becomes particularly crucial for adolescents as they make the transition from child to adult. Yet as adults we offer little coherent, direct instruction in such matters. The author advocates supporting girls as they explore complex and empowering literacy practices, particularly online.

  2. Digital Games, Gender and Learning in Engineering: Do Females Benefit as Much as Males?

    ERIC Educational Resources Information Center

    Joiner, Richard; Iacovides, Jo; Owen, Martin; Gavin, Carl; Clibbery, Stephen; Darling, Jos; Drew, Ben

    2011-01-01

    The aim of this paper was to explore whether there is a gender difference in the beneficial effects of Racing Academy, which is a video game used to support undergraduate students learning of Mechanical Engineering. One hundred and thirty-eight undergraduate students (15 females and 123 males) participated in the study. The students completed a…

  3. Refusing the Stereotype: Decoding Negative Gender Imagery through a School-Based Digital Media Literacy Program

    ERIC Educational Resources Information Center

    Berman, Naomi; White, Alexandra

    2013-01-01

    The media plays a significant role in shaping cultural norms and attitudes, concomitantly reinforcing "body" and "beauty" ideals and gender stereotypes. Unrealistic, photoshopped and stereotyped images used by the media, advertising and fashion industries influence young people's body image and impact on their feelings of body…

  4. Gender and environmental enrichment impact dopamine transporter expression after experimental traumatic brain injury.

    PubMed

    Wagner, Amy K; Chen, Xiangbai; Kline, Anthony E; Li, Youming; Zafonte, Ross D; Dixon, C Edward

    2005-10-01

    Dopamine (DA) systems are implicated in cognitive deficits following traumatic brain injury (TBI). Rodent studies have demonstrated that both environmental enrichment (EE) and sex hormones can influence DA systems. The dopamine transporter (DAT) plays a crucial role in regulating DA transmission, and previous work shows that DAT is decreased after TBI in males. Therefore, the purpose of this study was to examine the effects of gender and EE on frontal cortex and striatal DAT expression after TBI. Sprague-Dawley male (n = 24) and cycling female rats (n = 24) were placed into EE or standard housing after controlled cortical impact (2.7 mm, 4.0 m/s) injury or sham surgery (eight groups, n = 6/group). Four weeks post-surgery, bilateral frontal cortex and striatal DAT expression was examined via Western blot. Results demonstrated that there was a significant effect of injury, EE, and region on DAT expression (P < 0.05 all comparisons) on female groups. There were no significant DAT decreases in any region as a result of injury, however, EE did promote significant post-injury DAT decreases in the striatum and ipsilateral frontal cortex (P < 0.05 all comparisons) compared to female shams housed in the standard environment. For males, there was a significant effect of injury, EE, and region for male groups (P < 0.05 all comparisons). There were decreases in DAT expression in three regions studied for injured males housed in the standard environment compared to sham males in the standard environment (P < 0.05 all comparisons), however, EE did not add significantly to post-injury DAT decreases in these regions. These results suggest that CCI causes larger relative decreases in DAT expression for males compared to females and that treatment with EE has larger effects on post-injury DAT expression for females than males. These findings may have some relevance to treatment paradigms using dopaminergic neurostimulants after TBI. PMID:16023635

  5. Potato not Pope: human brain potentials to gender expectation and agreement in Spanish spoken sentences

    PubMed Central

    Wicha, Nicole Y.Y.; Bates, Elizabeth A.; Moreno, Eva M.; Kutas, Marta

    2012-01-01

    Event-related potentials were used to examine the role of grammatical gender in auditory sentence comprehension. Native Spanish speakers listened to sentence pairs in which a drawing depicting a noun was either congruent or incongruent with sentence meaning, and agreed or disagreed in gender with the immediately preceding spoken article. Semantically incongruent drawings elicited an N400 regardless of gender agreement. A similar negativity to prior articles of gender opposite to that of the contextually expected noun suggests that listeners predict specific words during comprehension. Gender disagreements at the drawing also elicited an increased negativity with a later onset and distribution distinct from the canonical N400, indicating that comprehenders attend to gender agreement, even when one of the words is only implicitly represented by a drawing. PMID:12853110

  6. Alternating gender incongruity: a new neuropsychiatric syndrome providing insight into the dynamic plasticity of brain-sex.

    PubMed

    Case, Laura K; Ramachandran, Vilayanur S

    2012-05-01

    , which we are currently exploring. Second, we base our hypotheses on ancient and modern associations between the left and right hemispheres and the male and female genders. By providing a case of sharp brain-sex shifts within individuals, we believe that the study of AGI could prove illuminating to scientific understanding of gender, body representation, and the nature of self. PMID:22364652

  7. A digital interactive human brain atlas based on Chinese visible human datasets for anatomy teaching.

    PubMed

    Li, Qiyu; Ran, Xu; Zhang, Shaoxiang; Tan, Liwen; Qiu, Mingguo

    2014-01-01

    As we know, the human brain is one of the most complicated organs in the human body, which is the key and difficult point in neuroanatomy and sectional anatomy teaching. With the rapid development and extensive application of imaging technology in clinical diagnosis, doctors are facing higher and higher requirement on their anatomy knowledge. Thus, to cultivate medical students to meet the needs of medical development today and to improve their ability to read and understand radiographic images have become urgent challenges for the medical teachers. In this context, we developed a digital interactive human brain atlas based on the Chinese visible human datasets for anatomy teaching (available for free download from http://www.chinesevisiblehuman.com/down/DHBA.rar). The atlas simultaneously provides views in all 3 primary planes of section. The main structures of the human brain have been anatomically labeled in all 3 views. It is potentially useful for anatomy browsing, user self-testing, and automatic student assessment. In a word, it is interactive, 3D, user friendly, and free of charge, which can provide a new, intuitive means for anatomy teaching. PMID:24336036

  8. Gender, Race, and Survival: A Study in Non-Small-Cell Lung Cancer Brain Metastases Patients Utilizing the Radiation Therapy Oncology Group Recursive Partitioning Analysis Classification

    SciTech Connect

    Videtic, Gregory M.M.; Reddy, Chandana A.; Chao, Samuel T.; Rice, Thomas W.; Adelstein, David J.; Barnett, Gene H.; Mekhail, Tarek M.; Vogelbaum, Michael A.; Suh, John H.

    2009-11-15

    Purpose: To explore whether gender and race influence survival in non-small-cell lung cancer (NSCLC) in patients with brain metastases, using our large single-institution brain tumor database and the Radiation Therapy Oncology Group recursive partitioning analysis (RPA) brain metastases classification. Methods and materials: A retrospective review of a single-institution brain metastasis database for the interval January 1982 to September 2004 yielded 835 NSCLC patients with brain metastases for analysis. Patient subsets based on combinations of gender, race, and RPA class were then analyzed for survival differences. Results: Median follow-up was 5.4 months (range, 0-122.9 months). There were 485 male patients (M) (58.4%) and 346 female patients (F) (41.6%). Of the 828 evaluable patients (99%), 143 (17%) were black/African American (B) and 685 (83%) were white/Caucasian (W). Median survival time (MST) from time of brain metastasis diagnosis for all patients was 5.8 months. Median survival time by gender (F vs. M) and race (W vs. B) was 6.3 months vs. 5.5 months (p = 0.013) and 6.0 months vs. 5.2 months (p = 0.08), respectively. For patients stratified by RPA class, gender, and race, MST significantly favored BFs over BMs in Class II: 11.2 months vs. 4.6 months (p = 0.021). On multivariable analysis, significant variables were gender (p = 0.041, relative risk [RR] 0.83) and RPA class (p < 0.0001, RR 0.28 for I vs. III; p < 0.0001, RR 0.51 for II vs. III) but not race. Conclusions: Gender significantly influences NSCLC brain metastasis survival. Race trended to significance in overall survival but was not significant on multivariable analysis. Multivariable analysis identified gender and RPA classification as significant variables with respect to survival.

  9. Effects of sugar rich diet on brain serotonin, hyperphagia and anxiety in animal model of both genders.

    PubMed

    Inam, Qurrat-ul-Aen; Ikram, Huma; Shireen, Erum; Haleem, Darakhshan Jabeen

    2016-05-01

    Lower levels of 5-hydroxytryptamine (5-HT; serotonin) in the brain elicit sugar craving, while ingestion of sugar rich diet improves mood and alleviates anxiety. Gender differences occur not only in brain serotonin metabolism but also in a serotonin mediated functional responses. The present study was therefore designed to investigate gender related differences on the effects of long term consumption of sugar rich diet on the metabolism of serotonin in the hypothalamus and whole brain which may be relevant with the hyperphagic and anxiety reducing effects of sugar rich diet. Male and female rats were fed freely on a sugar rich diet for five weeks. Hyperphagic effects were monitored by measuring total food intake and body weights changes during the intervention. Anxiolytic effects of sugar rich diet was monitored in light-dark transition test. The results show that ingestion of sugar rich diet decreased serotonin metabolism more in female than male rats. Anxiolytic effects were elicited only in male rats. Hyperphagia was comparable in both male and female rats. Finings would help in understanding the role of sugar rich diet-induced greater decreases of serotonin in sweet craving in women during stress. PMID:27166525

  10. Investigating Student Gender and Grade Level Differences in Digital Citizenship Behavior

    ERIC Educational Resources Information Center

    Lyons, Robert

    2012-01-01

    The rapid rise of technology, which has become embedded in all facets of 21st century society during the past decade, has fostered a corresponding rise in its misuse. Digital citizenship abuse, a relatively new phenomenon of this electronic age, is a rapidly growing global problem. Parents, schools, and society play roles in supporting appropriate…

  11. Healthy children show gender differences in correlations between nonverbal cognitive ability and brain activation during visual perception.

    PubMed

    Asano, Kohei; Taki, Yasuyuki; Hashizume, Hiroshi; Sassa, Yuko; Thyreau, Benjamin; Asano, Michiko; Takeuchi, Hikaru; Kawashima, Ryuta

    2014-08-01

    Humans perceive textual and nontextual information in visual perception, and both depend on language. In childhood education, students exhibit diverse perceptual abilities, such that some students process textual information better and some process nontextual information better. These predispositions involve many factors, including cognitive ability and learning preference. However, the relationship between verbal and nonverbal cognitive abilities and brain activation during visual perception has not yet been examined in children. We used functional magnetic resonance imaging to examine the relationship between nonverbal and verbal cognitive abilities and brain activation during nontextual visual perception in large numbers of children. A significant positive correlation was found between nonverbal cognitive abilities and brain activation in the right temporoparietal junction, which is thought to be related to attention reorienting. This significant positive correlation existed only in boys. These findings suggested that male brain activation differed from female brain activation, and that this depended on individual cognitive processes, even if there was no gender difference in behavioral performance. PMID:24937269

  12. Gender differences in platelet brain derived neurotrophic factor in patients with cardiovascular disease and depression.

    PubMed

    Williams, Marlene S; Ngongang, Chelsea K; Ouyang, Pam; Betoudji, Fabrice; Harrer, Christine; Wang, Nae-Yuh; Ziegelstein, Roy C

    2016-07-01

    Women have a higher prevalence of depression compared to men. Serum levels of Brain-derived neurotrophic factor (BDNF) are decreased in depression. BDNF may also have a protective role in the pathogenesis of coronary artery disease (CAD) or events. We examined whether there are gender differences in BDNF levels in patients with stable CAD and comorbid depression. We enrolled 37 patients (17 women) with stable CAD with and without depression from a single medical center. All patients had depression assessment with the Beck Depression Inventory-II questionnaire. Both plasma and platelet BDNF were measured in all patients using a standard ELISA method. Platelet BDNF levels were higher than plasma BDNF levels in the entire group (5903.9 ± 1915.6 vs 848.5 ± 460.5 pg/ml, p < 0.001). Women had higher platelet BDNF levels than men (6954.2 ± 1685.6 vs. 5011.2 ± 1653.5 pg/ml, p < 0.001). Women without depression (BDI-II < 5, n = 8) had higher platelet BDNF than men without depression (n = 8, 7382.8 ± 1633.1 vs 4811.7 ± 1642.3 pg/ml, p = 0.007). Women with no or minimal depression (BDI < 14, n = 14) had higher platelet BDNF levels than men with no or minimal depression (n = 18, 6900.2 ± 1486.6 vs 4972.9 ± 1568.9 pg/ml, p = 0.001). The plasma BDNF levels were similar between men and women in all categories of depression. In conclusion, women with stable CAD have increased platelet BDNF levels when compared to men with stable CAD regardless of their level of depression. Sex specific differences in BDNF could possibly indicate differences in factors linking platelet activation and depression in men and women. PMID:27082490

  13. Targeted enrichment and high-resolution digital profiling of mitochondrial DNA deletions in human brain.

    PubMed

    Taylor, Sean D; Ericson, Nolan G; Burton, Joshua N; Prolla, Tomas A; Silber, John R; Shendure, Jay; Bielas, Jason H

    2014-02-01

    Due largely to the inability to accurately quantify and characterize de novo deletion events, the mechanisms underpinning the pathogenic expansion of mtDNA deletions in aging and neuromuscular disorders remain poorly understood. Here, we outline and validate a new tool termed 'Digital Deletion Detection' (3D) that allows for high-resolution analysis of rare deletions occurring at frequencies as low as 1 × 10(-8) . 3D is a three-step process that includes targeted enrichment for deletion-bearing molecules, single-molecule partitioning of genomes into thousands of droplets for direct quantification via droplet digital PCR, and breakpoint characterization using massively parallel sequencing. Using 3D, we interrogated over 8 billion mitochondrial genomes to analyze the age-related dynamics of mtDNA deletions in human brain tissue. We demonstrate that the total deletion load increases with age, while the total number and diversity of unique deletions remain constant. Our data provide support for the hypothesis that expansion of pre-existing mutations is the primary factor contributing to age-related accumulation of mtDNA deletions. PMID:23911137

  14. Digital Games, Gender and Learning in Engineering: Do Females Benefit as Much as Males?

    NASA Astrophysics Data System (ADS)

    Joiner, Richard; Iacovides, Jo; Owen, Martin; Gavin, Carl; Clibbery, Stephen; Darling, Jos; Drew, Ben

    2011-04-01

    The aim of this paper was to explore whether there is a gender difference in the beneficial effects of Racing Academy, which is a video game used to support undergraduate students learning of Mechanical Engineering. One hundred and thirty-eight undergraduate students (15 females and 123 males) participated in the study. The students completed a pre-test a week before they started using Racing Academy. The pre-test consisted of a test of students' knowledge of engineering, and a measure of students' motivation towards studying engineering. A week after using Racing Academy the students completed a post-test which was identical to the pre-test, except it also included a measure of how frequently they used Racing Academy and how motivating the students found playing Racing Academy. We found that after playing Racing Academy the students learnt more about engineering and there was no gender difference in the beneficial effect of Racing Academy, however there is some evidence that, female students found Racing Academy more motivating than male students. The implications for the use and design of video games for supporting learning for both males and females are discussed.

  15. Patient radiation dose from computed tomography angiography and digital subtraction angiography of the brain

    NASA Astrophysics Data System (ADS)

    Netwong, Y.; Krisanachinda, A.

    2016-03-01

    The 64-row multidetector computed tomography angiography (64-MDCTA) provides vascular image quality of the brain similar to digital subtraction angiography (DSA), but the effective dose of CTA is lower than DSA studied in phantom. The purpose of this study is to evaluate the effective dose from 64-MDCTA and DSA. Effective dose (according to ICRP 103) from 64-MDCTA and DSA flat panel detector for cerebral vessels examination of the brain using standard protocols as recommended by the manufacturer was calculated for 30 cases of MDCTA (15 male and 15 female).The mean patient age was 49.5 (23-89) yrs. 30 cases of DSA (14 male and 16 female), the mean patient age was 46.8 (21-81) yrs. For CTA, the mean effective dose was 3.7 (2.82- 5.19) mSv. For DSA, the mean effective dose was 5.78 (3.3-10.06) mSv. The effective dose of CTA depends on the scanning protocol and scan length. Low tube current can reduce patient dose whereas the number of exposures and number of series in 3D rotational angiography (3D RA) resulted in increasing effective dose in DSA patients.

  16. Differential brain responses to social exclusion by one’s own versus opposite gender peers

    PubMed Central

    Bolling, Danielle Z.; Pelphrey, Kevin A.; Wyk, Brent C. Vander

    2015-01-01

    Human peer relations provide tangible benefits including food and protection, as well as emotional benefits. While social exclusion poses a threat to all of these benefits, the psychological threat is particularly susceptible to modulation by the relation of the excluders to the excluded person. The current study used functional magnetic resonance imaging to explore the effects of manipulating the gender relation of participants to their excluders during an interactive ball toss game. Ventral anterior cingulate cortex activation was higher during exclusion by same-gender peers, while right ventrolateral prefrontal cortex activation negatively correlated with self-reported distress in other-gender exclusion. Results imply that exclusion by one’s own gender is fundamentally different from exclusion by the opposite gender, and suggest a regulatory role for ventrolateral prefrontal cortex in response to out-group exclusion. Individual differences in implicit gender attitudes modulated neural responses to exclusion. The importance of these findings to investigations of social cognition is discussed. PMID:21981758

  17. Distribution of hematoporphyrin derivative in the rat 9l gliosarcoma brain tumor analyzed by digital video fluorescence microscopy.

    PubMed

    Boggan, J E; Walter, R; Edwards, M S; Borcich, J K; Davis, R L; Koonce, M; Berns, M W

    1984-12-01

    A digital video fluorescence microscopy technique was used to evaluate the distribution of hematoporphyrin derivative (HPD) in the rat intracerebral 9L gliosarcoma brain-tumor model at 4, 24, 48, and 72 hours after intravenous administration of 10 mg/kg of the drug. Compared to surrounding normal brain, there was significant preferential uptake of HPD into the tumor. In sections surveyed, fluorescence reached a maximum value by 24 hours; however, only 33% to 44% of the tumor was fluorescent. In contrast, fluorescence within the surrounding normal brain was maximum at 4 hours, but was present in less than 1% of the brain tissue evaluated. The effect of HPD sensitization to a laser light dose (633 nm) of 30 joules/sq cm delivered through the intact skull was evaluated histologically in 10 rats. A patchy coagulation necrosis, possibly corresponding to the distribution of HPD fluorescence seen within the tumor, was observed. There was evidence that photoradiation therapy (PRT) affects defective tumor vasculature and that a direct tumor cell toxicity spared normal brain tissue. Despite these findings, limited uptake of HPD in tumor and the brain adjacent to tumor may decrease the effectiveness of PRT in the 9L gliosarcoma brain-tumor model. Because of the similarity between the capillary system of the 9L tumor and human brain tumors, PRT may have a limited therapeutic effect in patients with malignant brain tumors. PMID:6239014

  18. Digit ratio (2D:4D) and gender inequalities across nations.

    PubMed

    Manning, John T; Fink, Bernhard; Trivers, Robert

    2014-01-01

    Gender inequality varies across nations, where such inequality is defined as the disproportionate representation of one sex over the other in desirable social, economic, and biological roles (typically male over female). Thus in Norway, 40% of parliamentarians are women, in the USA 17%, and in Saudi Arabia 0%. Some of this variation is associated with economic prosperity but there is evidence that this cause and effect can go in either direction. Here we show that within a population the average ratio of index (2D) to ring (4D) finger lengths (2D:4D)-a proxy measure of the relative degree to which offspring is exposed in utero to testosterone versus estrogen-is correlated with measures of gender inequality between nations. We compared male and female 2D:4D ratios to female parliamentary representation, labor force participation, female education level, maternal mortality rates, and juvenile pregnancy rates per nation in a sample of 29 countries. We found those nations who showed higher than expected female fetal exposure to testosterone (low 2D:4D) and lower than expected male exposure to fetal testosterone (high 2D:4D) had higher rates of female parliamentary representation, and higher female labor force participation. In short, the more similar the two sexes were in 2D:4D, the more equal were the two sexes in parliamentary and labor force participation. The other variables were not as strongly correlated. We suggest that higher than expected fetal testosterone in females and lower fetal testosterone in males may lead to high female representation in the national labor force and in parliament. PMID:25300052

  19. Gender-dependent behavioural impairment and brain metabolites in young adult rats after short term exposure to lead acetate.

    PubMed

    Mansouri, M T; Naghizadeh, B; López-Larrubia, P; Cauli, O

    2012-04-01

    We investigated the behavioural effects of short-term lead (Pb) exposure in adult rats producing blood Pb concentration (<10 μg/dL) below those associated with neurological impairment in occupationally exposed individuals. In order to assess gender differences, we performed parallel behavioural experiments in male and female rats. Exposure to Pb acetate (50 mg/L in drinking water) for 30-45 days induced behavioural alterations consisting in hyperactivity in a novel environment and impairment of spatial memory. These effects were observed only in male rats. Object recognition, motor coordination were unaffected by Pb exposure. Magnetic resonance spectroscopy allows in vivo assessment of main brain metabolites (glutamate/glutamine, creatine, myoinositol, N-acetylaspartate and choline) whose changes have been demonstrated in several central nervous system pathologies. Exposure to Pb did not affect metabolite profile in the striatum and increase myoinositol signal in the hippocampus of male rats. The increase in myoinositol in hippocampus suggests early Pb-induced alteration in glial metabolism in this brain region and may represent a potential marker of early brain dysfunction during Pb exposure. PMID:22285975

  20. Brain Correlates of Stuttering and Syllable Production: Gender Comparison and Replication.

    ERIC Educational Resources Information Center

    Ingham, Roger J.; Fox, Peter T.; Ingham, Janis C.; Xiong, Jinhu; Zamarripa, Frank; Hardies, L. Jean; Lancaster, Jack L.

    2004-01-01

    This article reports a gender replication study of the P. T. Fox et a. (2000) performance correlation analysis of neural systems that distinguish between normal and stuttered speech in adult males. Positron-emission tomographic (PET) images of cerebral blood flow (CBF) were correlated with speech behavior scores obtained during PET imaging for 10…

  1. Integrating histology and MRI in the first digital brain of common squirrel monkey, Saimiri sciureus

    PubMed Central

    Sun, Peizhen; Parvathaneni, Prasanna; Schilling, Kurt G.; Gao, Yurui; Janve, Vaibhav; Anderson, Adam; Landman, Bennett A.

    2015-01-01

    This effort is a continuation of development of a digital brain atlas of the common squirrel monkey, Saimiri sciureus, a New World monkey with functional and microstructural organization of central nervous system similar to that of humans. Here, we present the integration of histology with multi-modal magnetic resonance imaging (MRI) atlas constructed from the brain of an adult female squirrel monkey. The central concept of this work is to use block face photography to establish an intermediate common space in coordinate system which preserves the high resolution in-plane resolution of histology while enabling 3-D correspondence with MRI. In vivo MRI acquisitions include high resolution T2 structural imaging (300 µm isotropic) and low resolution diffusion tensor imaging (600 um isotropic). Ex vivo MRI acquisitions include high resolution T2 structural imaging and high resolution diffusion tensor imaging (both 300 µm isotropic). Cortical regions were manually annotated on the co-registered volumes based on published histological sections in-plane. We describe mapping of histology and MRI based data of the common squirrel monkey and construction of a viewing tool that enable online viewing of these datasets. The previously descried atlas MRI is used for its deformation to provide accurate conformation to the MRI, thus adding information at the histological level to the MRI volume. This paper presents the mapping of single 2D image slice in block face as a proof of concept and this can be extended to map the atlas space in 3D coordinate system as part of the future work and can be loaded to an XNAT system for further use. PMID:25914510

  2. Integrating histology and MRI in the first digital brain of common squirrel monkey, Saimiri sciureus

    NASA Astrophysics Data System (ADS)

    Sun, Peizhen; Parvathaneni, Prasanna; Schilling, Kurt G.; Gao, Yurui; Janve, Vaibhav; Anderson, Adam; Landman, Bennett A.

    2015-03-01

    This effort is a continuation of development of a digital brain atlas of the common squirrel monkey, Saimiri sciureus, a New World monkey with functional and microstructural organization of central nervous system similar to that of humans. Here, we present the integration of histology with multi-modal magnetic resonance imaging (MRI) atlas constructed from the brain of an adult female squirrel monkey. The central concept of this work is to use block face photography to establish an intermediate common space in coordinate system which preserves the high resolution in-plane resolution of histology while enabling 3-D correspondence with MRI. In vivo MRI acquisitions include high resolution T2 structural imaging (300 μm isotropic) and low resolution diffusion tensor imaging (600 um isotropic). Ex vivo MRI acquisitions include high resolution T2 structural imaging and high resolution diffusion tensor imaging (both 300 μm isotropic). Cortical regions were manually annotated on the co-registered volumes based on published histological sections in-plane. We describe mapping of histology and MRI based data of the common squirrel monkey and construction of a viewing tool that enable online viewing of these datasets. The previously descried atlas MRI is used for its deformation to provide accurate conformation to the MRI, thus adding information at the histological level to the MRI volume. This paper presents the mapping of single 2D image slice in block face as a proof of concept and this can be extended to map the atlas space in 3D coordinate system as part of the future work and can be loaded to an XNAT system for further use.

  3. In vivo imaging of scattering and absorption properties of exposed brain using a digital red-green-blue camera

    NASA Astrophysics Data System (ADS)

    Nishidate, Izumi; Yoshida, Keiichiro; Kawauchi, Satoko; Sato, Shunichi; Sato, Manabu

    2014-03-01

    We investigate a method to estimate the spectral images of reduced scattering coefficients and the absorption coefficients of in vivo exposed brain tissues in the range from visible to near-infrared wavelength (500-760 nm) based on diffuse reflectance spectroscopy using a digital RGB camera. In the proposed method, the multi-spectral reflectance images of in vivo exposed brain are reconstructed from the digital red, green blue images using the Wiener estimation algorithm. The Monte Carlo simulation-based multiple regression analysis for the absorbance spectra is then used to specify the absorption and scattering parameters of brain tissue. In this analysis, the concentration of oxygenated hemoglobin and that of deoxygenated hemoglobin are estimated as the absorption parameters whereas the scattering amplitude a and the scattering power b in the expression of μs'=aλ-b as the scattering parameters, respectively. The spectra of absorption and reduced scattering coefficients are reconstructed from the absorption and scattering parameters, and finally, the spectral images of absorption and reduced scattering coefficients are estimated. The estimated images of absorption coefficients were dominated by the spectral characteristics of hemoglobin. The estimated spectral images of reduced scattering coefficients showed a broad scattering spectrum, exhibiting larger magnitude at shorter wavelengths, corresponding to the typical spectrum of brain tissue published in the literature. In vivo experiments with exposed brain of rats during CSD confirmed the possibility of the method to evaluate both hemodynamics and changes in tissue morphology due to electrical depolarization.

  4. ADNP: A major autism mutated gene is differentially distributed (age and gender) in the songbird brain.

    PubMed

    Kleiman, Gal Hacohen; Barnea, Anat; Gozes, Illana

    2015-10-01

    ADNP is a protein necessary for brain development, important for brain plasticity, cognitive and social functioning, characteristics that are all impaired in autism and in the Adnp(+/-) mouse model, in a sex-dependent manner. ADNP was originally discovered as a protein that is secreted from glial cells in response to vasoactive intestinal peptide (VIP). VIP is a major neuroprotective peptide in the CNS and PNS and was also associated with social recognition in rodents and aggression, pair-bonding and parental behaviors in birds. Comparative sequence alignment revealed high evolutionary conservation of ADNP in Chordata. Despite its importance in brain function, ADNP has never been studied in birds. Zebra finches (Taeniopygia guttata) are highly social songbirds that have a sexually dichotomous anatomical brain structure, with males demonstrating a developed song system, presenting a model to study behavior and potential sexually dependent fundamental differences. Here, using quantitative real time polymerase chain reaction (qRT-PCR), we discovered sexually dichotomous and age related differences in ADNP mRNA expression in three different regions of the song bird brain-cerebellum, cerebrum, and brain stem. Higher levels of ADNP mRNA were specifically found in young male compared to the female cerebrum, while aging caused a significant 2 and 3-fold decrease in the female and male cerebrum, respectively. Furthermore, a comparison between the three tested brain regions revealed unique sex-dependent ADNP mRNA distribution patterns, affected by aging. Future studies are aimed at deciphering the function of ADNP in birds, toward a better molecular understanding of sexual dichotomy in singing behavior in birds. PMID:25895853

  5. Gender on the Brain: A Case Study of Science Communication in the New Media Environment

    PubMed Central

    O’Connor, Cliodhna; Joffe, Helene

    2014-01-01

    Neuroscience research on sex difference is currently a controversial field, frequently accused of purveying a ‘neurosexism’ that functions to naturalise gender inequalities. However, there has been little empirical investigation of how information about neurobiological sex difference is interpreted within wider society. This paper presents a case study that tracks the journey of one high-profile study of neurobiological sex differences from its scientific publication through various layers of the public domain. A content analysis was performed to ascertain how the study was represented in five domains of communication: the original scientific article, a press release, the traditional news media, online reader comments and blog entries. Analysis suggested that scientific research on sex difference offers an opportunity to rehearse abiding cultural understandings of gender. In both scientific and popular contexts, traditional gender stereotypes were projected onto the novel scientific information, which was harnessed to demonstrate the factual truth and normative legitimacy of these beliefs. Though strains of misogyny were evident within the readers’ comments, most discussion of the study took pains to portray the sexes’ unique abilities as equal and ‘complementary’. However, this content often resembled a form of benevolent sexism, in which praise of women’s social-emotional skills compensated for their relegation from more esteemed trait-domains, such as rationality and productivity. The paper suggests that embedding these stereotype patterns in neuroscience may intensify their rhetorical potency by lending them the epistemic authority of science. It argues that the neuroscience of sex difference does not merely reflect, but can actively shape the gender norms of contemporary society. PMID:25354280

  6. Gender on the brain: a case study of science communication in the new media environment.

    PubMed

    O'Connor, Cliodhna; Joffe, Helene

    2014-01-01

    Neuroscience research on sex difference is currently a controversial field, frequently accused of purveying a 'neurosexism' that functions to naturalise gender inequalities. However, there has been little empirical investigation of how information about neurobiological sex difference is interpreted within wider society. This paper presents a case study that tracks the journey of one high-profile study of neurobiological sex differences from its scientific publication through various layers of the public domain. A content analysis was performed to ascertain how the study was represented in five domains of communication: the original scientific article, a press release, the traditional news media, online reader comments and blog entries. Analysis suggested that scientific research on sex difference offers an opportunity to rehearse abiding cultural understandings of gender. In both scientific and popular contexts, traditional gender stereotypes were projected onto the novel scientific information, which was harnessed to demonstrate the factual truth and normative legitimacy of these beliefs. Though strains of misogyny were evident within the readers' comments, most discussion of the study took pains to portray the sexes' unique abilities as equal and 'complementary'. However, this content often resembled a form of benevolent sexism, in which praise of women's social-emotional skills compensated for their relegation from more esteemed trait-domains, such as rationality and productivity. The paper suggests that embedding these stereotype patterns in neuroscience may intensify their rhetorical potency by lending them the epistemic authority of science. It argues that the neuroscience of sex difference does not merely reflect, but can actively shape the gender norms of contemporary society. PMID:25354280

  7. Measurement Invariance of the Digital Natives Assessment Scale across Gender in a Sample of Turkish University Students

    ERIC Educational Resources Information Center

    Ursavas, Ömer Faruk; Kabakçi Yurdakul, Isil; Türk, Mesut; Mcilroy, David

    2016-01-01

    With reference to the digital natives' debate, there is a gap on digital natives' characteristics. To fill this gap, the Digital Natives Assessment Scale was developed to measure students' assessment of the degree to which they perceived themselves to possess the attributes of digital natives. The scale was developed within the Turkish language…

  8. Digital lock-in detection system based on single photon counting for near-infrared functional brain imaging

    NASA Astrophysics Data System (ADS)

    Meng, Wei; Guo, Hui; Liu, Ming; Yi, Xi; Wu, Linhui; Zhao, Huijuan; Gao, Feng

    2013-03-01

    Near infrared (NIR) diffuse optical imaging (DOI) are increasingly used to detect hemodynamic changes in the cerebral cortex induced by brain activity. For the sake of capturing the dynamic changes in real-time imaging applications, such as brain imaging, digital lock-in detection technique could be applied. Using particular modulation and sampling constraints and averaging filters, one can achieve optimal noise reduction and discrimination between sources in different modulation frequencies. In this paper, we designed and developed a compact dual-wavelength continuous wave DOI system based on the single photon counting digital lock-in detection technique. According to the frequency division multiplexing light source coding technique, sine waves with different frequencies are generated so as to amplitude-modulate two laser sources with different wavelengths. The diffuse light is detected by photomultiplier tubes (PMTs) and the data is collected by the detection channels simultaneously. A digital lock-in detection circuit for photon counting measurement module and a DDS (Direct Digital Synthesizer) signal generation module were separately implemented in two FPGA development platforms. To validate the feasibility and functionality of the developed system, a series of experimental tests were performed. Preliminary results show that the system could be used to reconstruct the absorption coefficient and could separate the response of the dual wavelength sources which were modulated by sine signals of different frequencies effectively. In addition, several imaging experiments were performed on the semi-infinite solid phantom to find the "best imaging position" for a given source-detector placement.

  9. A Digital Atlas of Middle to Large Brain Vessels and Their Relation to Cortical and Subcortical Structures

    PubMed Central

    Viviani, Roberto

    2016-01-01

    While widely distributed, the vascular supply of the brain is particularly prominent in certain anatomical structures because of the high vessel density or their large size. A digital atlas of middle to large vessels in Montreal Neurological Institute (MNI) coordinates is here presented, obtained from a sample of N = 38 healthy participants scanned with the time-of-flight (TOF) magnetic resonance technique, and normalized with procedures analogous to those commonly used in functional neuroimaging studies. Spatial colocalization of brain parenchyma and vessels is shown to affect specific structures such as the anteromedial face of the temporal lobe, the cortex surrounding the Sylvian fissure (Sy), the anterior cingular cortex, and the ventral striatum. The vascular frequency maps presented here provide objective information about the vascularization of the brain, and may assist in the interpretation of data in studies where vessels are a potential confound. PMID:26924965

  10. Age and gender effects on human brain anatomy: a voxel-based morphometric study in healthy elderly.

    PubMed

    Smith, Charles D; Chebrolu, Himachandra; Wekstein, David R; Schmitt, Frederick A; Markesbery, William R

    2007-07-01

    The adult human brain shrinks slowly with age, but the regional specificity and tissue class specificity of this loss is unclear. Subjects (n=122) were healthy aged participants in a longitudinal cohort who undergo periodic standardized cognitive and clinical examination. Multi-spectral segmentation of magnetic resonance images into grey matter (GM), white matter (WM) and CSF was performed on cross-sectional image data using a custom template and calculated prior probability maps. Global differences were evaluated by fitting a regression model for absolute and normalized subject GM, WM, and CSF values. Global and regional patterns of GM, WM and CSF differences were assessed using optimized voxel-based morphometry (VBM). GM volume decreased with age at a rate of 2.4 cm(3)/year (-0.18%/year); CSF increased by 2.5 cm(3)/year (0.20%/year). Regression analyses showed no significant decrease in WM volume, but a focal WM decrease with age was detected in the anterior corpus callosum using VBM. Diffuse reductions of GM volume were seen with age in the frontal, parietal, and temporal cortex, cerebellum and basal ganglia. Relative regional differences in cortical GM volume with age occurred in the frontal, parietal and temporal lobes, but not in medial temporal lobe or in posterior cingulate. We did not observe significant gender effects. These findings establish a baseline for comparison with pathologic changes in human brain volume between ages 58 and 95 years. PMID:16774798

  11. Gender differences in brain structure and resting-state functional connectivity related to narcissistic personality

    PubMed Central

    Yang, Wenjing; Cun, Lingli; Du, Xue; Yang, Junyi; Wang, Yanqiu; Wei, Dongtao; Zhang, Qinglin; Qiu, Jiang

    2015-01-01

    Although cognitive and personality studies have observed gender differences in narcissism, the neural bases of these differences remain unknown. The current study combined the voxel-based morphometry and resting state functional connectivity (rsFC) analyses to explore the sex-specific neural basis of narcissistic personality. The VBM results showed that the relationship between narcissistic personality and regional gray matter volume (rGMV) differed between sexes. Narcissistic scores had a significant positive correlation with the rGMV of the right SPL in females, but not in males. Further analyses were conducted to investigate the sex-specific relationship between rsFC and narcissism, using right SPL/frontal eye fields (FEF) as the seed regions (key nodes of the dorsal attention network, DAN). Interestingly, decreased anticorrelations between the right SPL/FEF and areas of the precuneus and middle frontal gyrus (key nodes of the the default mode network, DMN) were associated with higher narcissistic personality scores in males, whereas females showed the opposite tendency. The findings indicate that gender differences in narcissism may be associated with differences in the intrinsic and dynamic interplay between the internally-directed DMN and the externally-directed TPN. Morphometry and functional connectivity analyses can enhance our understanding of the neural basis of sex-specific narcissism. PMID:26109334

  12. Brain

    MedlinePlus

    ... will return after updating. Resources Archived Modules Updates Brain Cerebrum The cerebrum is the part of the ... the outside of the brain and spinal cord. Brain Stem The brain stem is the part of ...

  13. Does gender matter? Differences in social-emotional behavior among infants and toddlers before and after mild traumatic brain injury: a preliminary study.

    PubMed

    Kaldoja, Mari-Liis; Kolk, Anneli

    2015-06-01

    Traumatic brain injury is a common cause of acquired disability in childhood. While much is known about cognitive sequelae of brain trauma, gender-specific social-emotional problems in children with mild traumatic brain injury is far less understood. The aims of the study were to investigate gender differences in social-emotional behavior before and after mild traumatic brain injury. Thirty-five 3- to 65-month-old children with mild traumatic brain injury and 70 controls were assessed with Ages and Stages Questionnaires: Social-Emotional. Nine months later, 27 of 35 patients and 54 of 70 controls were reassessed. We found that before injury, boys had more self-regulation and autonomy difficulties and girls had problems with adaptive functioning. Nine months after injury, boys continued to struggle with self-regulation and autonomy and new difficulties with interaction had emerged, whereas in girls, problems in interaction had evolved. Even mild traumatic brain injury in early childhood disrupts normal social-emotional development having especially devastating influence on interaction skills. PMID:25143483

  14. A customizable 3-dimensional digital atlas of the canary brain in multiple modalities.

    PubMed

    Vellema, Michiel; Verschueren, Jacob; Van Meir, Vincent; Van der Linden, Annemie

    2011-07-15

    Songbirds are well known for their ability to learn their vocalizations by imitating conspecific adults. This uncommon skill has led to many studies examining the behavioral and neurobiological processes involved in vocal learning. Canaries display a variable, seasonally dependent, vocal behavior throughout their lives. This trait makes this bird species particularly valuable to study the functional relationship between the continued plasticity in the singing behavior and alterations in the anatomy and physiology of the brain. In order to optimally interpret these types of studies, a detailed understanding of the brain anatomy is essential. Because traditional 2-dimensional brain atlases are limited in the information they can provide about the anatomy of the brain, here we present a 3-dimensional MRI-based atlas of the canary brain. Using multiple imaging protocols we were able to maximize the number of detectable brain regions, including most of the areas involved in song perception, learning, and production. The brain atlas can readily be used to determine the stereotactic location of delineated brain areas at any desirable head angle. Alternatively the brain data can be used to determine the ideal orientation of the brain for stereotactic injections, electrophysiological recordings, and brain sectioning. The 3-dimensional canary brain atlas presented here is freely available and is easily adaptable to support many types of neurobiological studies, including anatomical, electrophysiological, histological, explant, and tracer studies. PMID:21565273

  15. The importance of combining MRI and large-scale digital histology in neuroimaging studies of brain connectivity and disease

    PubMed Central

    Annese, Jacopo

    2012-01-01

    One of the major issues hindering a comprehensive connectivity model for the human brain is the difficulty in linking Magnetic Resonance Imaging (MRI) measurements to anatomical evidence produced by histological methods. In vivo and postmortem neuroimaging methodologies are still largely incompatible in terms of sample size, scale, and resolution. To help bridge the hiatus between different approaches we have established a program that characterizes the brain of individual subjects, combining MRI with postmortem neuroanatomy. The direct correlation of MRI and histological features is possible, because registered images from different modalities represent the same regions in the same brain. Comparisons are also facilitated by large-scale, digital microscopy techniques that afford images of the whole-brain sections at cellular resolution. The goal is to create a neuroimaging catalog representative of discrete age groups and specific neurological conditions. Individually, the datasets allow for investigating the relationship between different modalities; combined, they provide sufficient predictive power to inform analyses and interpretations made in the context of non-invasive studies of brain connectivity and disease. PMID:22536182

  16. Gossamer Threads: Commentary on the Impact of Digital Technology on the Developing Brain and the Capacity for Empathy.

    PubMed

    Bjorklund, Pamela

    2016-01-01

    This essay explores the impact of digital technology on brain development and other areas of human growth including the capacity for empathy, which is fundamental to successful relationships, is an essential survival skill, and is an important source of moral knowledge. Reflections on a teenaged daughter's immersion in technology, coupled with evidence for the mixed consequences of such, weave together the gossamer threads of disparate, sometimes conflicting information about the explosion of digital technology over the past few decades, the impossibility of multitasking, the mixed effects of digital technology on brain development, and what it all might mean for human development generally and the moral capacity for empathic response in particular. While the essence of the commentary is intentionally interdisciplinary and weaves together disparate threads of multidisciplinary knowledge, it has important implications for nursing-with its relational core, unique as well as shared bodies of moral and scientific knowledge, and interprofessional health care goals to maximize human growth and well-being across the life span in both health and illness. PMID:26836995

  17. Gender difference in electrical brain activity during presentation of various film excerpts with different emotional content.

    PubMed

    Dimpfel, W; Wedekind, W; Keplinger, I

    2003-05-30

    Electrical activity of the human brain has been monitored using socalled charge mode (Laplacian estimates) during the exposure with short video film excerpts of 7 min duration. Eighty subjects (50% male and female) watched 5 different film excerpts (disney, animal, comedy, erotic and sex scenes) separated by 3 min pause. Comparison to a reference period of 7 min without video exposure revealed strong decreases in alpha and beta power starting from the electrode position T6 (right temporal) and spread to other brain areas with stronger attentional stimuli e.g. during the erotic and sex films. Highly statistically significant differences were observed between male and female in temporal areas, who in general developed stronger decreases than males. Females on the other hand produced significant increases in fronto-central delta and theta power which could be interpreted as expression of higher appreciation, whereas the decreases in alpha power in general are understood as signs of higher attention. The data are further proof that recording the computer aided quantitative EEG is a very fruitful and promising approach in psychophysiology. PMID:12844473

  18. Chronic Lead Exposure and Mixed Factors of Gender×Age×Brain Regions Interactions on Dendrite Growth, Spine Maturity and NDR Kinase

    PubMed Central

    Xue, Weizhen; Yang, Qian-Qian; Wang, Shuang; Xu, Yi; Wang, Hui-Li

    2015-01-01

    NDR1/2 kinase is essential in dendrite morphology and spine formation, which is regulated by cellular Ca2+. Lead (Pb) is a potent blocker of L-type calcium channel and our recent work showed Pb exposure impairs dendritic spine outgrowth in hippocampal neurons in rats. But the sensitivity of Pb-induced spine maturity with mixed factors (gender×age×brain regions) remains unknown. This study aimed to systematically investigate the effect of Pb exposure on spine maturity in rat brain with three factors (gender×age×brain regions), as well as the NDR1/2 kinase expression. Sprague–Dawley rats were exposed to Pb from parturition to postnatal day 30, 60, 90, respectively. Golgi-Cox staining was used to examine spine maturity. Western blot assay was applied to measure protein expression and real-time fluorescence quantitative PCR assay was used to examine mRNA levels. The results showed chronic Pb exposure significantly decreased dendritic length and impaired spine maturity in both rat hippocampus and medial prefrontal cortex. The impairment of dendritic length induced by Pb exposure tended to adolescence > adulthood, hippocampus > medial prefrontal cortex and female > male. Pb exposure induced significant damage in spine maturity during adolescence and early adult while little damage during adult in male rat brain and female medial prefrontal cortex. Besides, there was sustained impairment from adolescence to adulthood in female hippocampus. Interestingly, impairment of spine maturity followed by Pb exposure was correlated with NDR1/2 kinase. The reduction of NDR1/2 kinase protein expression after Pb exposure was similar to the result of spine maturity. In addition, NDR2 and their substrate Rabin3 mRNA levels were significantly decreased by Pb exposure in developmental rat brain. Taken together, Pb exposure impaired dendrite growth and maturity which was subject to gender×age×brain regions effects and related to NDR1/2 signal expression. PMID:26368815

  19. Age and gender based biomechanical shape and size analysis of the pediatric brain.

    PubMed

    Danelson, Kerry A; Geer, Carol P; Stitzel, Joel D; Slice, Dennis E; Takhounts, Erik G

    2008-11-01

    Injuries caused by motor vehicle crashes (MVCs) are the leading cause of head injury and death for children in the United States. This study aims to describe the shape and size (morphologic) changes of the cerebrum, cerebellum, brainstem, and ventricles of the pediatric occupant to better predict injury and assess how these changes affect finite element model (FEM) response. To quantify morphologic differences in the brain, a Generalized Procrustes Analysis (GPA) with a sliding landmark method was conducted to isolate morphologic changes using magnetic resonance images of 63 normal subjects. This type of geometric morphometric analysis was selected for its ability to identify homologous landmarks on structures with few true landmarks and isolate the shape and size of the individuals studied. From the resulting landmark coordinates, the shape and size changes were regressed against age to develop a model describing morphologic changes in the pediatric brain as a function of age. The most statistically significant shape change was in the cerebrum with p-values of 0.00346 for males and 0.00829 for females. The age-based model explains over 80% of the variation in size in the cerebrum. Using size and shape models, affine transformations were applied to the SIMon FEM to determine differences in response given differences in size and size plus shape. The geometric centroid of the elements exceeding 15% strain was calculated and compared to the geometric centroid of the entire structure. Given the same Haversine pulse, the centroid location, a metric for the spatial distribution of the elements exceeding an injury threshold, varied based on which transformation was applied to the model. To assess the overall response of the model, three injury metrics were examined to determine the magnitude of the metrics each element sustained and the overall volume of elements that experienced that value. These results suggested that the overall response of the model was driven by the

  20. Can Sex Differences in Science Be Tied to the Long Reach of Prenatal Hormones? Brain Organization Theory, Digit Ratio (2D/4D), and Sex Differences in Preferences and Cognition.

    PubMed

    Valla, Jeffrey; Ceci, Stephen J

    2011-03-01

    Brain organization theory posits a cascade of physiological and behavioral changes initiated and shaped by prenatal hormones. Recently, this theory has been associated with outcomes including gendered toy preference, 2D/4D digit ratio, personality characteristics, sexual orientation, and cognitive profile (spatial, verbal, and mathematical abilities). We examine the evidence for this claim, focusing on 2D/4D and its putative role as a biomarker for organizational features that influence cognitive abilities/interests predisposing males toward mathematically and spatially intensive careers. Although massive support exists for early brain organization theory overall, there are myriad inconsistencies, alternative explanations, and outright contradictions that must be addressed while still taking the entire theory into account. Like a fractal within the larger theory, the 2D/4D hypothesis mirrors this overall support on a smaller scale while likewise suffering from inconsistencies (positive, negative, and sex-dependent correlations), alternative explanations (2D/4D related to spatial preferences rather than abilities per se), and contradictions (feminine 2D/4D in men associated with higher spatial ability). Using the debate over brain organization theory as the theoretical stage, we focus on 2D/4D evidence as an increasingly important player on this stage, a demonstrative case in point of the evidential complexities of the broader debate, and an increasingly important topic in its own right. PMID:22164187

  1. Can Sex Differences in Science Be Tied to the Long Reach of Prenatal Hormones? Brain Organization Theory, Digit Ratio (2D/4D), and Sex Differences in Preferences and Cognition

    PubMed Central

    Valla, Jeffrey; Ceci, Stephen J.

    2011-01-01

    Brain organization theory posits a cascade of physiological and behavioral changes initiated and shaped by prenatal hormones. Recently, this theory has been associated with outcomes including gendered toy preference, 2D/4D digit ratio, personality characteristics, sexual orientation, and cognitive profile (spatial, verbal, and mathematical abilities). We examine the evidence for this claim, focusing on 2D/4D and its putative role as a biomarker for organizational features that influence cognitive abilities/interests predisposing males toward mathematically and spatially intensive careers. Although massive support exists for early brain organization theory overall, there are myriad inconsistencies, alternative explanations, and outright contradictions that must be addressed while still taking the entire theory into account. Like a fractal within the larger theory, the 2D/4D hypothesis mirrors this overall support on a smaller scale while likewise suffering from inconsistencies (positive, negative, and sex-dependent correlations), alternative explanations (2D/4D related to spatial preferences rather than abilities per se), and contradictions (feminine 2D/4D in men associated with higher spatial ability). Using the debate over brain organization theory as the theoretical stage, we focus on 2D/4D evidence as an increasingly important player on this stage, a demonstrative case in point of the evidential complexities of the broader debate, and an increasingly important topic in its own right. PMID:22164187

  2. A rat brain MRI template with digital stereotaxic atlas of fine anatomical delineations in paxinos space and its automated application in voxel-wise analysis.

    PubMed

    Nie, Binbin; Chen, Kewei; Zhao, Shujun; Liu, Junhua; Gu, Xiaochun; Yao, Qunli; Hui, Jiaojie; Zhang, Zhijun; Teng, Gaojun; Zhao, Chunjie; Shan, Baoci

    2013-06-01

    This study constructs a rat brain T2 -weighted magnetic resonance imaging template including olfactory bulb and a compatible digital atlas. The atlas contains 624 carefully delineated brain structures based on the newest (2005) edition of rat brain atlas by Paxinos and Watson. An automated procedure, as an SPM toolbox, was introduced for spatially normalizing individual rat brains, conducting statistical analysis and visually localizing the results in the Atlas coordinate space. The brain template/atlas and the procedure were evaluated using functional images between rats with the right side middle cerebral artery occlusion (MCAO) and normal controls. The result shows that the brain region with significant signal decline in the MCAO rats was consistent with the occlusion position. PMID:22287270

  3. Digital Gaming for Improving the Functioning of People With Traumatic Brain Injury: Protocol of a Feasibility Study

    PubMed Central

    Korkeila, Jyrki; Kauppi, Kaisa; Kaakinen, Johanna K; Holm, Suvi; Vahlo, Jukka; Tenovuo, Olli; Hämäläinen, Heikki; Sarajuuri, Jaana; Rantanen, Pekka; Orenius, Tage; Koponen, Aki

    2016-01-01

    Background Traumatic brain injury (TBI) is a critical public health problem. The recovery process for people with TBI is typically slow and dependent on complex and intensive assisted rehabilitation programs. Objective To evaluate the effects and feasibility of digital games for cognitive functioning and general well-being among people with traumatic brain injury. Methods This is a single-site feasibility study conducted in Finland, which uses a pragmatic, randomized controlled trial with three arms, and will recruit patients from the Turku University Hospital, Division of Clinical Neurosciences in Finland. Participants must meet the following inclusion criteria: (1) a Finnish speaking adult, aged 18-65 years; (2) diagnosed with a traumatic brain injury (diagnostic criteria ICD-10, S06.X, T90.5) in the University Hospital; (3) access to a TV, a computer, and the Internet at home; (4) not an active digital gamer (5 hours or less a week); (5) willing to participate in the study. Participants must have been discharged from the neurologic treatment period for traumatic brain injury for over 12 months before the commencement of the trial, and they may not have actively participated in cognitive rehabilitation during the 3 months prior to the trial. Written informed consent will be mandatory for acceptance into the trial. Exclusion criteria are as follows: (1) sensory, cognitive, or physical impairment (eg, severe cognitive impairment); (2) a deficiency restricting the use of computers or computer game control system unaided (eg, impairment in vision, severe astigmatism, hemiplegia, disorder in visuospatial perception, dysfunction of the central vestibular system); (3) apathy identified in previous neuropsychological evaluations; (4) diagnosed severe mental disorders (eg, schizophrenia or severe depressive disorders to be identified in medical records as the secondary diagnosis). Results The preparatory phase for the study is fulfilled. Recruitment started in June 2015

  4. Gender Modulates the APOE ε4 Effect in Healthy Older Adults: Convergent Evidence from Functional Brain Connectivity and Spinal Fluid Tau Levels

    PubMed Central

    Damoiseaux, Jessica S.; Seeley, William W.; Zhou, Juan; Shirer, William R.; Coppola, Giovanni; Karydas, Anna; Rosen, Howard J.; Miller, Bruce L.; Kramer, Joel H.; Greicius, Michael D.

    2012-01-01

    We examined whether the effect of APOE genotype on functional brain connectivity is modulated by gender in healthy older human adults. Our results confirm significantly decreased connectivity in the default mode network in healthy older APOE ε4 carriers compared to ε3 homozygotes. More importantly, further testing revealed a significant interaction between APOE genotype and gender in the precuneus, a major default mode hub. Female ε4 carriers showed significantly reduced default mode connectivity compared to either female ε3 homozygotes or male ε4 carriers, whereas male ε4 carriers differed minimally from male ε3 homozygotes. An additional analysis in an independent sample of healthy elderly using an independent marker of Alzheimer’s disease, i.e. spinal fluid levels of tau, provided corresponding evidence for this gender by APOE interaction. Taken together, these results converge with previous work showing a higher prevalence of the ε4 allele among women with Alzheimer’s disease and, critically, demonstrate that this interaction between APOE genotype and gender is detectable in the preclinical period. PMID:22699906

  5. Beyond age and gender: Relationships between cortical and subcortical brain volume and cognitive-motor abilities in school-age children

    PubMed Central

    Pangelinan, Melissa M.; Zhang, Guangyu; VanMeter, John W.; Clark, Jane E.; Hatfield, Bradley D.; Haufler, Amy J.

    2010-01-01

    There is growing evidence that cognitive and motor functions are interrelated and may rely on the development of the same cortical and subcortical neural structures. However, no study to date has examined the relationships between brain volume, cognitive ability, and motor ability in typically developing children. The NIH MRI Study of Normal Brain Development consists of a large, longitudinal database of structural MRI and performance measures from a battery of neuropsychological assessments from typically developing children. This dataset provides a unique opportunity to examine relationships between the brain and cognitive-motor abilities. A secondary analysis was conducted on data from 172 children between the ages of 6 to 13 years with up to 2 measurement occasions (initial testing and 2-year follow-up). Linear mixed effects modeling was employed to account for age and gender effects on the development of specific cortical and subcortical volumes as well as behavioral performance measures of interest. Above and beyond the effects of age and gender, significant relationships were found between general cognitive ability (IQ) and the volume of subcortical brain structures (cerebellum and caudate) as well as spatial working memory and the putamen. In addition, IQ was found to be related to global and frontal gray matter volume as well as parietal gray and white matter. At the behavioral level, general cognitive ability was also found to be related to visuomotor ability (pegboard) and executive function (spatial working memory). These results support the notion that cognition and motor skills may be fundamentally interrelated at both the levels of behavior and brain structure. PMID:21078402

  6. Automatic Testing and Assessment of Neuroanatomy Using a Digital Brain Atlas: Method and Development of Computer- and Mobile-Based Applications

    ERIC Educational Resources Information Center

    Nowinski, Wieslaw L.; Thirunavuukarasuu, Arumugam; Ananthasubramaniam, Anand; Chua, Beng Choon; Qian, Guoyu; Nowinska, Natalia G.; Marchenko, Yevgen; Volkau, Ihar

    2009-01-01

    Preparation of tests and student's assessment by the instructor are time consuming. We address these two tasks in neuroanatomy education by employing a digital media application with a three-dimensional (3D), interactive, fully segmented, and labeled brain atlas. The anatomical and vascular models in the atlas are linked to "Terminologia…

  7. Video gaming and gender differences in digital and printed reading performance among 15-year-olds students in 26 countries.

    PubMed

    Borgonovi, Francesca

    2016-04-01

    Video games are a favorite leisure-time activity among teenagers worldwide. This study examines cross-national gender differences in reading achievement and video gaming and whether video gaming explains gender differences in reading achievement and differences in performance between paper-based and computer-based reading. We use data from a representative sample of 145,953 students from 26 countries who sat the PISA 2012 assessments and provided self-reports on use of video games. Although boys tend to have poorer results in both the computer-based and the paper-based reading assessments, boys' under achievement is smaller when the assessment is delivered on computer than when it is delivered on paper. Boys underperformance compared to girls in the two reading assessments is particularly pronounced among low-achieving students. Among both boys and girls moderate use of single-player games is associated with a performance advantage. However, frequent engagement with collaborative online games is generally associated with a steep reduction in achievement, particularly in the paper-based test and particularly among low-achieving students. Excessive gaming may hinder academic achievement, but moderate gaming can promote positive student outcomes. In many countries video gaming explains the difference in the gender gap in reading between the paper-based and the computer-based assessments. PMID:26874783

  8. 3' tag digital gene expression profiling of human brain and universal reference RNA using Illumina Genome Analyzer

    PubMed Central

    2009-01-01

    Background Massive parallel sequencing has the potential to replace microarrays as the method for transcriptome profiling. Currently there are two protocols: full-length RNA sequencing (RNA-SEQ) and 3'-tag digital gene expression (DGE). In this preliminary effort, we evaluated the 3' DGE approach using two reference RNA samples from the MicroArray Quality Control Consortium (MAQC). Results Using Brain RNA sample from multiple runs, we demonstrated that the transcript profiles from 3' DGE were highly reproducible between technical and biological replicates from libraries constructed by the same lab and even by different labs, and between two generations of Illumina's Genome Analyzers. Approximately 65% of all sequence reads mapped to mitochondrial genes, ribosomal RNAs, and canonical transcripts. The expression profiles of brain RNA and universal human reference RNA were compared which demonstrated that DGE was also highly quantitative with excellent correlation of differential expression with quantitative real-time PCR. Furthermore, one lane of 3' DGE sequencing, using the current sequencing chemistry and image processing software, had wider dynamic range for transcriptome profiling and was able to detect lower expressed genes which are normally below the detection threshold of microarrays. Conclusion 3' tag DGE profiling with massive parallel sequencing achieved high sensitivity and reproducibility for transcriptome profiling. Although it lacks the ability of detecting alternative splicing events compared to RNA-SEQ, it is much more affordable and clearly out-performed microarrays (Affymetrix) in detecting lower abundant transcripts. PMID:19917133

  9. Selected Gray Matter Volumes and Gender but Not Basal Ganglia nor Cerebellum Gyri Discriminate Left Versus Right Cerebral Hemispheres: Multivariate Analyses in human Brains at 3T.

    PubMed

    Roldan-Valadez, Ernesto; Suarez-May, Marcela A; Favila, Rafael; Aguilar-Castañeda, Erika; Rios, Camilo

    2015-07-01

    Interest in the lateralization of the human brain is evident through a multidisciplinary number of scientific studies. Understanding volumetric brain asymmetries allows the distinction between normal development stages and behavior, as well as brain diseases. We aimed to evaluate volumetric asymmetries in order to select the best gyri able to classify right- versus left cerebral hemispheres. A cross-sectional study performed in 47 right-handed young-adults healthy volunteers. SPM-based software performed brain segmentation, automatic labeling and volumetric analyses for 54 regions involving the cerebral lobes, basal ganglia and cerebellum from each cerebral hemisphere. Multivariate discriminant analysis (DA) allowed the assembling of a predictive model. DA revealed one discriminant function that significantly differentiated left vs. right cerebral hemispheres: Wilks' λ = 0.008, χ(2) (9) = 238.837, P < 0.001. The model explained 99.20% of the variation in the grouping variable and depicted an overall predictive accuracy of 98.8%. With the influence of gender; the selected gyri able to discriminate between hemispheres were middle orbital frontal gyrus (g.), angular g., supramarginal g., middle cingulum g., inferior orbital frontal g., calcarine g., inferior parietal lobule and the pars triangularis inferior frontal g. Specific brain gyri are able to accurately classify left vs. right cerebral hemispheres by using a multivariate approach; the selected regions correspond to key brain areas involved in attention, internal thought, vision and language; our findings favored the concept that lateralization has been evolutionary favored by mental processes increasing cognitive efficiency and brain capacity. PMID:25902919

  10. A digital atlas of ion channel expression patterns in the two-week-old rat brain.

    PubMed

    Shcherbatyy, Volodymyr; Carson, James; Yaylaoglu, Murat; Jäckle, Katharina; Grabbe, Frauke; Brockmeyer, Maren; Yavuz, Halenur; Eichele, Gregor

    2015-01-01

    The approximately 350 ion channels encoded by the mammalian genome are a main pillar of the nervous system. We have determined the expression pattern of 320 channels in the two-week-old (P14) rat brain by means of non-radioactive robotic in situ hybridization. Optimized methods were developed and implemented to generate stringently coronal brain sections. The use of standardized methods permits a direct comparison of expression patterns across the entire ion channel expression pattern data set and facilitates recognizing ion channel co-expression. All expression data are made publically available at the Genepaint.org database. Inwardly rectifying potassium channels (Kir, encoded by the Kcnj genes) regulate a broad spectrum of physiological processes. Kcnj channel expression patterns generated in the present study were fitted with a deformable subdivision mesh atlas produced for the P14 rat brain. This co-registration, when combined with numerical quantification of expression strengths, allowed for semi-quantitative automated annotation of expression patterns as well as comparisons among and between Kcnj subfamilies. The expression patterns of Kcnj channel were also cross validated against previously published expression patterns of Kcnj channel genes. PMID:25284011

  11. Mutations in BMP4 Cause Eye, Brain, and Digit Developmental Anomalies: Overlap between the BMP4 and Hedgehog Signaling Pathways

    PubMed Central

    Bakrania, Preeti; Efthymiou, Maria; Klein, Johannes C.; Salt, Alison; Bunyan, David J.; Wyatt, Alex; Ponting, Chris P.; Martin, Angela; Williams, Steven; Lindley, Victoria; Gilmore, Joanne; Restori, Marie; Robson, Anthony G.; Neveu, Magella M.; Holder, Graham E.; Collin, J Richard O.; Robinson, David O.; Farndon, Peter; Johansen-Berg, Heidi; Gerrelli, Dianne; Ragge, Nicola K.

    2008-01-01

    Developmental ocular malformations, including anophthalmia-microphthalmia (AM), are heterogeneous disorders with frequent sporadic or non-Mendelian inheritance. Recurrent interstitial deletions of 14q22-q23 have been associated with AM, sometimes with poly/syndactyly and hypopituitarism. We identify two further cases of AM (one with associated pituitary anomalies) with a 14q22-q23 deletion. Using a positional candidate gene approach, we analyzed the BMP4 (Bone Morphogenetic Protein-4) gene and identified a frameshift mutation (c.226del2, p.S76fs104X) that segregated with AM, retinal dystrophy, myopia, brain anomalies, and polydactyly in a family and a nonconservative missense mutation (c.278A→G, p.E93G) in a highly conserved base in another family. MR imaging and tractography in the c.226del2 proband revealed a primary brain developmental disorder affecting thalamostriatal and callosal pathways, also present in the affected grandmother. Using in situ hybridization in human embryos, we demonstrate expression of BMP4 in optic vesicle, developing retina and lens, pituitary region, and digits strongly supporting BMP4 as a causative gene for AM, pituitary, and poly/syndactyly. Because BMP4 interacts with HH signaling genes in animals, we evaluated gene expression in human embryos and demonstrate cotemporal and cospatial expression of BMP4 and HH signaling genes. We also identified four cases, some of whom had retinal dystrophy, with “low-penetrant” mutations in both BMP4 and HH signaling genes: SHH (Sonic Hedgehog) or PTCH1 (Patched). We propose that BMP4 is a major gene for AM and/or retinal dystrophy and brain anomalies and may be a candidate gene for myopia and poly/syndactyly. Our finding of low-penetrant variants in BMP4 and HH signaling partners is suggestive of an interaction between the two pathways in humans. PMID:18252212

  12. Ganzfeld perceptual field and gender effects on short-term memory as a function of rate of digit presentation.

    PubMed

    Vitulli, W F; Laconsay, K L; Shepard, H A

    1996-06-01

    Efforts to enhance short term memory for digit span (in serial recall) included the Ganzfeld perceptual field and variation in the rate (interstimulus interval: 1 sec., 2 sec., 3 sec.) of 25 auditorily presented computer-generated random numbers (1 to 5). Undergraduate volunteers (52 men and 91 women) wore goggles consisting of halves of translucent ping-pong balls while viewing a red lamp and listening to 60 decibels of white noise. Control subjects wore goggles with clear plastic lenses. Participants were instructed to recall 25 random digits in the correct series (vocalized sequentially through headphones worn by the subjects) immediately after their presentations. A mixed 2 x 2 x 3 split plot analysis of variance yielded a significant effect for digit rates, and post hoc Scheffe tests of multiple comparisons showed differences in recall between interstimulus intervals of 1 and 2 sec., 1 and 3 sec., and 2 and 3 sec. Other Scheffe comparisons showed that men scored higher than women with the 3-sec. interstimulus interval and with the "clear" perceptual field. Ganzfeld may have reduced distractibility for women as compared with recall following the "clear" perceptual field. Serial-position effects favored "primacy," yet the "recency effect" was seen within the last 5 serial positions. PMID:8823899

  13. Converting laserdisc video to digital video: a demonstration project using brain animations.

    PubMed Central

    Jao, C S; Hier, D B; Brint, S U

    1995-01-01

    Interactive laserdiscs are of limited value in large group learning situations due to the expense of establishing multiple workstations. The authors implemented an alternative to laserdisc video by using indexed digital video combined with an expert system. High-quality video was captured from a laserdisc player and combined with waveform audio into an audio-video-interleave (AVI) file format in the Microsoft Video-for-Windows environment (Microsoft Corp., Seattle, WA). With the use of an expert system, a knowledge-based computer program provided random access to these indexed AVI files. The program can be played on any multimedia computer without the need for laserdiscs. This system offers a high level of interactive video without the overhead and cost of a laserdisc player. PMID:7534614

  14. An automatic fuzzy-based multi-temporal brain digital subtraction angiography image fusion algorithm using curvelet transform and content selection strategy.

    PubMed

    Momeni, Saba; Pourghassem, Hossein

    2014-08-01

    Recently image fusion has prominent role in medical image processing and is useful to diagnose and treat many diseases. Digital subtraction angiography is one of the most applicable imaging to diagnose brain vascular diseases and radiosurgery of brain. This paper proposes an automatic fuzzy-based multi-temporal fusion algorithm for 2-D digital subtraction angiography images. In this algorithm, for blood vessel map extraction, the valuable frames of brain angiography video are automatically determined to form the digital subtraction angiography images based on a novel definition of vessel dispersion generated by injected contrast material. Our proposed fusion scheme contains different fusion methods for high and low frequency contents based on the coefficient characteristic of wrapping second generation of curvelet transform and a novel content selection strategy. Our proposed content selection strategy is defined based on sample correlation of the curvelet transform coefficients. In our proposed fuzzy-based fusion scheme, the selection of curvelet coefficients are optimized by applying weighted averaging and maximum selection rules for the high frequency coefficients. For low frequency coefficients, the maximum selection rule based on local energy criterion is applied to better visual perception. Our proposed fusion algorithm is evaluated on a perfect brain angiography image dataset consisting of one hundred 2-D internal carotid rotational angiography videos. The obtained results demonstrate the effectiveness and efficiency of our proposed fusion algorithm in comparison with common and basic fusion algorithms. PMID:24957394

  15. Automated classification of brain tumor type in whole-slide digital pathology images using local representative tiles.

    PubMed

    Barker, Jocelyn; Hoogi, Assaf; Depeursinge, Adrien; Rubin, Daniel L

    2016-05-01

    Computerized analysis of digital pathology images offers the potential of improving clinical care (e.g. automated diagnosis) and catalyzing research (e.g. discovering disease subtypes). There are two key challenges thwarting computerized analysis of digital pathology images: first, whole slide pathology images are massive, making computerized analysis inefficient, and second, diverse tissue regions in whole slide images that are not directly relevant to the disease may mislead computerized diagnosis algorithms. We propose a method to overcome both of these challenges that utilizes a coarse-to-fine analysis of the localized characteristics in pathology images. An initial surveying stage analyzes the diversity of coarse regions in the whole slide image. This includes extraction of spatially localized features of shape, color and texture from tiled regions covering the slide. Dimensionality reduction of the features assesses the image diversity in the tiled regions and clustering creates representative groups. A second stage provides a detailed analysis of a single representative tile from each group. An Elastic Net classifier produces a diagnostic decision value for each representative tile. A weighted voting scheme aggregates the decision values from these tiles to obtain a diagnosis at the whole slide level. We evaluated our method by automatically classifying 302 brain cancer cases into two possible diagnoses (glioblastoma multiforme (N = 182) versus lower grade glioma (N = 120)) with an accuracy of 93.1 % (p < 0.001). We also evaluated our method in the dataset provided for the 2014 MICCAI Pathology Classification Challenge, in which our method, trained and tested using 5-fold cross validation, produced a classification accuracy of 100% (p < 0.001). Our method showed high stability and robustness to parameter variation, with accuracy varying between 95.5% and 100% when evaluated for a wide range of parameters. Our approach may be useful to automatically

  16. Navigating through digital folders uses the same brain structures as real world navigation

    PubMed Central

    Benn, Yael; Bergman, Ofer; Glazer, Liv; Arent, Paris; Wilkinson, Iain D.; Varley, Rosemary; Whittaker, Steve

    2015-01-01

    Efficient storage and retrieval of digital data is the focus of much commercial and academic attention. With personal computers, there are two main ways to retrieve files: hierarchical navigation and query-based search. In navigation, users move down their virtual folder hierarchy until they reach the folder in which the target item is stored. When searching, users first generate a query specifying some property of the target file (e.g., a word it contains), and then select the relevant file when the search engine returns a set of results. Despite advances in search technology, users prefer retrieving files using virtual folder navigation, rather than the more flexible query-based search. Using fMRI we provide an explanation for this phenomenon by demonstrating that folder navigation results in activation of the posterior limbic (including the retrosplenial cortex) and parahippocampal regions similar to that previously observed during real-world navigation in both animals and humans. In contrast, search activates the left inferior frontal gyrus, commonly observed in linguistic processing. We suggest that the preference for navigation may be due to the triggering of automatic object finding routines and lower dependence on linguistic processing. We conclude with suggestions for future computer systems design. PMID:26423226

  17. Navigating through digital folders uses the same brain structures as real world navigation.

    PubMed

    Benn, Yael; Bergman, Ofer; Glazer, Liv; Arent, Paris; Wilkinson, Iain D; Varley, Rosemary; Whittaker, Steve

    2015-01-01

    Efficient storage and retrieval of digital data is the focus of much commercial and academic attention. With personal computers, there are two main ways to retrieve files: hierarchical navigation and query-based search. In navigation, users move down their virtual folder hierarchy until they reach the folder in which the target item is stored. When searching, users first generate a query specifying some property of the target file (e.g., a word it contains), and then select the relevant file when the search engine returns a set of results. Despite advances in search technology, users prefer retrieving files using virtual folder navigation, rather than the more flexible query-based search. Using fMRI we provide an explanation for this phenomenon by demonstrating that folder navigation results in activation of the posterior limbic (including the retrosplenial cortex) and parahippocampal regions similar to that previously observed during real-world navigation in both animals and humans. In contrast, search activates the left inferior frontal gyrus, commonly observed in linguistic processing. We suggest that the preference for navigation may be due to the triggering of automatic object finding routines and lower dependence on linguistic processing. We conclude with suggestions for future computer systems design. PMID:26423226

  18. Different contributions of visual and motor brain areas during liking judgments of same- and different-gender bodies.

    PubMed

    Cazzato, V; Mele, S; Urgesi, C

    2016-09-01

    Previous neuroimaging studies have shown that body aesthetic appreciation involves the activation of both visual and motor areas, supporting a role of sensorimotor embodiment in aesthetic processing. Causative evidence, however, that neural activity in these areas is crucial for reliable aesthetic body appreciation has so far provided only for extrastriate body area (EBA), while the functional role played by premotor regions remained less clear. Here, we applied short trains of repetitive transcranial magnetic stimulation (rTMS) over bilateral dorsal premotor cortex (dPMC) and EBA during liking judgments of female and male bodies varying in weight and implied motion. We found that both dPMC and EBA are necessary for aesthetic body appreciation, but their relative contribution depends on the model's gender. While dPMC-rTMS decreased the liking judgments of same-, but not of different-gender models, EBA-rTMS increased the liking judgments of different-, but not of same-gender models. Relative contributions of motor and visual areas may reflect processing of diverse aesthetic properties, respectively implied motion vs. body form, and/or greater sensorimotor embodiment of same- vs. different-gender bodies. Results suggest that aesthetic body processing is subserved by a network of motor and visual areas, whose relative contribution may depend on the specific stimulus and task. PMID:27235869

  19. [Frequency-spatial organization of brain electrical activity in creative verbal thinking: role of the gender factor].

    PubMed

    Razumnikova, O M; Bryzgalova, A O

    2005-01-01

    Gender differences in EEG patterns associated with verbal creativity were studied by EEG mapping. The EEGs of 18 males and 21 females (right-handed university students) were recorded during a performance of Remote Associates Task (RAT) compared with the letter-fluency and simple associate's tasks. Gender differences were found in a factor structure of the indices of verbal thinking and a score of generating words was greater in women than men. No significant gender differences in originality of associations were revealed, however, gender-related differences in the EEG-patterns were found at the final and initial stages of RAT. In men, the beta2-power was increased in both hemispheres at the beginning of test. To the end of testing, the power of oscillations in the beta2 band increased only in the central part of the cortex. In women, the beta2-power was increased to a greater extent in the right than in the left hemisphere at the initial stage of task performance, whereas the final stage was characterized by a relative decrease in beta-activity in parietotemporal cortical regions and increase in the left prefrontal region. It is suggested that the verbal creative thinking in men is based mostly on "insight" strategy whereas women additionally involve the "intellectual" strategy. PMID:16217962

  20. Technical and organizational considerations for the long-term maintenance and development of digital brain atlases and web-based databases.

    PubMed

    Ito, Kei

    2010-01-01

    Digital brain atlas is a kind of image database that specifically provide information about neurons and glial cells in the brain. It has various advantages that are unmatched by conventional paper-based atlases. Such advantages, however, may become disadvantages if appropriate cares are not taken. Because digital atlases can provide unlimited amount of data, they should be designed to minimize redundancy and keep consistency of the records that may be added incrementally by different staffs. The fact that digital atlases can easily be revised necessitates a system to assure that users can access previous versions that might have been cited in papers at a particular period. To inherit our knowledge to our descendants, such databases should be maintained for a very long period, well over 100 years, like printed books and papers. Technical and organizational measures to enable long-term archive should be considered seriously. Compared to the initial development of the database, subsequent efforts to increase the quality and quantity of its contents are not regarded highly, because such tasks do not materialize in the form of publications. This fact strongly discourages continuous expansion of, and external contributions to, the digital atlases after its initial launch. To solve these problems, the role of the biocurators is vital. Appreciation of the scientific achievements of the people who do not write papers, and establishment of the secure academic career path for them, are indispensable for recruiting talents for this very important job. PMID:20661458

  1. Technical and Organizational Considerations for the Long-Term Maintenance and Development of Digital Brain Atlases and Web-Based Databases

    PubMed Central

    Ito, Kei

    2010-01-01

    Digital brain atlas is a kind of image database that specifically provide information about neurons and glial cells in the brain. It has various advantages that are unmatched by conventional paper-based atlases. Such advantages, however, may become disadvantages if appropriate cares are not taken. Because digital atlases can provide unlimited amount of data, they should be designed to minimize redundancy and keep consistency of the records that may be added incrementally by different staffs. The fact that digital atlases can easily be revised necessitates a system to assure that users can access previous versions that might have been cited in papers at a particular period. To inherit our knowledge to our descendants, such databases should be maintained for a very long period, well over 100 years, like printed books and papers. Technical and organizational measures to enable long-term archive should be considered seriously. Compared to the initial development of the database, subsequent efforts to increase the quality and quantity of its contents are not regarded highly, because such tasks do not materialize in the form of publications. This fact strongly discourages continuous expansion of, and external contributions to, the digital atlases after its initial launch. To solve these problems, the role of the biocurators is vital. Appreciation of the scientific achievements of the people who do not write papers, and establishment of the secure academic career path for them, are indispensable for recruiting talents for this very important job. PMID:20661458

  2. Gender dysphoria

    MedlinePlus

    Gender dysphoria is a condition in which there is a conflict between a person's physical gender and the ... Gender dysphoria used to be known as gender identity disorder. People with gender dysphoria may act as members ...

  3. In vivo multispectral imaging of the absorption and scattering properties of exposed brain using a digital red-green-blue camera

    NASA Astrophysics Data System (ADS)

    Yoshida, Keiichiro; Ishizuka, Tomohiro; Mizushima, Chiharu; Nishidate, Izumi; Kawauchi, Satoko; Sato, Shunichi; Sato, Manabu

    2015-04-01

    To evaluate multi-spectral images of the absorption and scattering properties in the cerebral cortex of rat brain, we investigated spectral reflectance images estimated by the Wiener estimation method using a digital red-green-blue camera. A Monte Carlo simulation-based multiple regression analysis for the corresponding spectral absorbance images at nine wavelengths (500, 520, 540, 560, 570, 580, 600, 730, and 760 nm) was then used to specify the absorption and scattering parameters. The spectral images of absorption and reduced scattering coefficients were reconstructed from the absorption and scattering parameters. We performed in vivo experiments on exposed rat brain to confirm the feasibility of this method. The estimated images of the absorption coefficients were dominated by hemoglobin spectra. The estimated images of the reduced scattering coefficients had a broad scattering spectrum, exhibiting a larger magnitude at shorter wavelengths, corresponding to the typical spectrum of brain tissue published in the literature.

  4. Gender-specific Associations of the Brain-derived Neurotrophic Factor Val66Met Polymorphism with Neurocognitive and Clinical Features in Schizophrenia

    PubMed Central

    Kim, Sung-Wan; Lee, Ju-Yeon; Kang, Hee-Ju; Kim, Seon-Young; Bae, Kyung-Yeol; Kim, Jae-Min; Shin, Il-Seon; Yoon, Jin-Sang

    2016-01-01

    Objective To explore associations of the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism with cognitive functioning and psychopathology in patients with schizophrenia. Methods We included 133 subjects meeting the DSM-IV criteria for schizophrenia who were in the post-acute stage of the disease. BDNF Val66Met genotypes were identified via polymerase chain reaction. The computerized neurocognitive function battery, Positive and Negative Syndrome Scale (PANSS), Calgary Depression Scale for Schizophrenia (CDSS), Social and Occupational Functioning Scale (SOFAS), and the Subjective Well-being under Neuroleptic Treatment (SWN-K) were administered. Gender-stratified sub-analysis was also conducted to identify gender-specific patterns in the findings. Results In male patients, no significant difference in any measure by BDNF genotype was evident. In female patients, scores on the CDSS and total PANSS and all subscales were significantly higher in valine (Val) carriers. In addition, scores on the SOFAS and SWN-K were significantly lower in Val carriers. In terms of neurocognitive measures, female patients with the Val allele had significantly poorer reaction times and fewer correct responses on the Continuous Performance Test (CPT) and the Trail Making Test (Parts A and B). After adjustment of PANSS total scores and log-transformed CDSS scores, CPT outcomes were significantly poorer in female patients with than in those without the Val allele. Conclusion Gender-specific associations of the Val allele with poor neurocognitive function and more severe psychopathology were evident. Further studies are required to explore the mechanisms of these differences and the potential utility of the BDNF genotype as a predictor of outcome in patients with schizophrenia. PMID:27489381

  5. Differential Expression of Brain Cannabinoid Receptors between Repeatedly Stressed Males and Females may Play a Role in Age and Gender-Related Difference in Traumatic Brain Injury: Implications from Animal Studies

    PubMed Central

    Xing, Guoqiang; Carlton, Janis; Jiang, Xiaolong; Wen, Jillian; Jia, Min; Li, He

    2014-01-01

    Inconsistent gender differences in the outcome of TBI have been reported. The mechanism is unknown. In a recent male animal study, repeated stress followed by TBI had synergistic effects on brain gene expression and caused greater behavioral deficits. Because females are more likely to develop anxiety after stress and because anxiety is mediated by cannabinoid receptors (CBRs) (CB1 and CB2), there is a need to compare CB1 and CB2 expression in stressed males and females. CB1 and CB2 mRNA expression was determined in the amygdala, hippocampus, prefrontal cortex (PFC), and hypothalamus of adolescent male and female rats after 3 days of repeated tail-shock stress using qPCR. PFC CB1 and CB2 protein levels were determined using Western blot techniques. Both gender and stress had significant effects on brain CB1 mRNA expression levels. Overall, females showed significantly higher CB1 and CB2 mRNA levels in all brain regions than males (p < 0.01). Repeated stress reduced CB1 mRNA levels in the amygdala, hippocampus, and PFC (p < 0.01, each). A gender × stress interaction was found in CB1 mRNA level in the hippocampus (p < 0.05), hypothalamus (p < 0.01), and PFC (p < 0.01). Within-sex one-way ANOVA analysis showed decreased CB1 mRNA in the hippocampus, hypothalamus, and PFC of stressed females (p < 0.01, each) but increased CB1 mRNA levels in the hypothalamus of stressed males (p < 01). There was a gender and stress interaction in prefrontal CB1 receptor protein levels (p < 0.05), which were decreased in stressed females only (p < 0.05). Prefrontal CB2 protein levels were decreased in both male and female animals after repeated stress (p < 0.05, each). High basal levels of CBR expression in young naïve females could protect against TBI damage whereas stress-induced CBR deficits could predict a poor outcome of TBI in repeatedly stressed females. Further animal studies could help evaluate this possibility. PMID:25221540

  6. Gender- and region-dependent changes of redox biomarkers in the brain of successfully aging LOU/C rats.

    PubMed

    Moyse, Emmanuel; Arseneault, Madeleine; Gaudreau, Pierrette; Ferland, Guylaine; Ramassamy, Charles

    2015-07-01

    The LOU/C (LOU) rat is an obesity resistant strain with higher longevity and healthspan than common rats. The management of oxidative stress being important to successful aging, we characterized this process in the aging LOU rat. Male/female LOU rats were euthanized at 4, 20, and 29 months. Macrodissected hippocampus, striatum, parietal cortex, cerebellum were assayed for tissue concentrations of glutathione (GSH), gamma-glutamyl-cysteine-synthetase (γ-GCS), total thiols, protein carbonyls, mRNAs of clusterin and the known protective enzymes thioredoxine-1 (TRX-1), glutaredoxine-1 (GLRX-1), superoxide dismutase-1 (SOD-1). Brain levels of GSH, γ-GCS, total thiols remained constant with age, except for GSH and γ-GCS which decreases in females. Clusterin, TRX-1, GLRX-1, SOD-1 mRNA levels were maintained or increased in the hippocampus with age. Age-dependency of the markers differed between sexes, with SOD-1 and TRX-1 decreases out of hippocampus in females. Since antioxidants were reported to decrease with age in the brain of Wistar rats, maintenance of GSH levels and of protective enzymes mRNA levels in the LOU rat brain could contribute to the preservation of cognitive functions in old age. Altogether, the successful aging of LOU rats may, at least in part, involve the conservation of functional antioxidant mechanisms in the brain, supporting the oxidative stress theory of aging. PMID:25956602

  7. Frequency-spatial organization of brain electrical activity in creative verbal thought: the role of the gender factor.

    PubMed

    Razumnikova, O M; Bryzgalov, A O

    2006-07-01

    Gender-related differences in the EEG correlates of creative thought were studied by mapping EEG power during performance of a Remote Associations Task as compared with verbal word-generation and simple association tasks. Right-handed students (18 male, 21 female) took part in the studies. Gender-related differences were seen in the factor structure of measures of verbal activity and in the larger number of words generated for a given letter in women than in men. In terms of the originality of the associations, men and women showed no significant difference, though the dynamics of the power of the beta-2 rhythm during creative thought differed. In males, the search for original associations was accompanied by increases in beta-2 power in both hemispheres at the initial stages of performing the task, with local increases in the beta-2 rhythm in the central parts of the cortex at the end of testing. In women, the increase in beta-2 power was initially greater in the right hemisphere than the left, while there was a relative decrease in beta activity in the parietal-temporal areas of the cortex and an increase in the left anterior frontal areas at the terminal stage of task performance. It is suggested that creative verbal thought is based mostly on an "insight" strategy in males, while women additionally use an "intellectual" strategy. PMID:16783518

  8. On the Brain Basis of Digital Daze in Millennial Minds: Rejoinder to "Digital Technology and Student Cognitive Development: The Neuroscience of the University Classroom"

    ERIC Educational Resources Information Center

    Brown, Timothy T.

    2016-01-01

    In this issue, Cavanaugh, Giapponi, and Golden (2016) have discussed the new prominent role of digital devices in the lives of students; the possible impact of these widely-used technologies on developing, learning minds; and the relevance of new cognitive neuroscience research and technologies for better understanding the potential effects of…

  9. Mutually temporally independent connectivity patterns: a new framework to study the dynamics of brain connectivity at rest with application to explain group difference based on gender.

    PubMed

    Yaesoubi, Maziar; Miller, Robyn L; Calhoun, Vince D

    2015-02-15

    Functional connectivity analysis of the human brain is an active area in fMRI research. It focuses on identifying meaningful brain networks that have coherent activity either during a task or in the resting state. These networks are generally identified either as collections of voxels whose time series correlate strongly with a pre-selected region or voxel, or using data-driven methodologies such as independent component analysis (ICA) that compute sets of maximally spatially independent voxel weightings (component spatial maps (SMs)), each associated with a single time course (TC). Studies have shown that regardless of the way these networks are defined, the activity coherence among them has a dynamic nature which is hard to estimate with global coherence analysis such as correlation or mutual information. Sliding window analyses in which functional network connectivity (FNC) is estimated separately at each time window is one of the more widely employed approaches to studying the dynamic nature of functional network connectivity (dFNC). Observed FNC patterns are summarized and replaced with a smaller set of prototype connectivity patterns ("states" or "components"), and then a dynamical analysis is applied to the resulting sequences of prototype states. In this work we are looking for a small set of connectivity patterns whose weighted contributions to the dynamically changing dFNCs are independent of each other in time. We discuss our motivation for this work and how it differs from existing approaches. Also, in a group analysis based on gender we show that males significantly differ from females by occupying significantly more combinations of these connectivity patterns over the course of the scan. PMID:25485713

  10. Revisiting Geschwind's hypothesis on brain lateralisation: a functional MRI study of digit ratio (2D:4D) and sex interaction effects on spatial working memory.

    PubMed

    Kalmady, Sunil Vasu; Agarwal, Sri Mahavir; Shivakumar, Venkataram; Jose, Dania; Venkatasubramanian, Ganesan; Reddy, Y C Janardhan

    2013-01-01

    The Geschwind-Behan-Galaburda (GBG) hypothesis links cerebral lateralisation with prenatal testosterone exposure. Digit ratio measures in adults have been established as potential markers of foetal sex hormonal milieu. The aim of the study was to evaluate the sex-dependent interaction of digit ratio measures and cerebral lateralization as well as their neurohemodynamic correlates using functional MRI (fMRI). Digit ratio measures-ratio of index finger (2D) length to ring finger (4D) length (2D:4D) and difference between 2D:4D of two hands, i.e., right minus left (DR-L)-were calculated using high resolution digital images in 70 right-handed participants (42 men) based on reliable and valid method. fMRI was acquired during the performance of a spatial working memory task in a subset of 25 individuals (14 men), and analysed using Statistical Parametric Mapping 8 (SPM8) and the Laterality Index toolbox for SPM8. Men had significantly less bilateral 2D:4D than women. There was a significant negative correlation between right 2D:4D and 2-Back task accuracy (2BACC) in women. A significant sex-by-right 2D:4D interaction was observed in left parahippocampal gyrus activation. Additionally, sex-by-DR-L interaction was observed in left IPL activation. DR-L showed a significant positive correlation with the whole brain Laterality Index (LI), and LI, in turn, demonstrated a significant negative correlation with 2BACC. Our study observations suggest several novel sex-differential relationships between 2D:4D measures and fMRI activation during spatial working memory task performance. Given the pre-existing background data supporting digit ratio measures as putative indicator of prenatal sex hormonal milieu, our study findings add support to the Geschwind-Behan-Galaburda (GBG) hypothesis. PMID:23458090

  11. Multispectral imaging of absorption and scattering properties of in vivo exposed rat brain using a digital red-green-blue camera

    NASA Astrophysics Data System (ADS)

    Yoshida, Keiichiro; Nishidate, Izumi; Ishizuka, Tomohiro; Kawauchi, Satoko; Sato, Shunichi; Sato, Manabu

    2015-05-01

    In order to estimate multispectral images of the absorption and scattering properties in the cerebral cortex of in vivo rat brain, we investigated spectral reflectance images estimated by the Wiener estimation method using a digital RGB camera. A Monte Carlo simulation-based multiple regression analysis for the corresponding spectral absorbance images at nine wavelengths (500, 520, 540, 560, 570, 580, 600, 730, and 760 nm) was then used to specify the absorption and scattering parameters of brain tissue. In this analysis, the concentrations of oxygenated hemoglobin and that of deoxygenated hemoglobin were estimated as the absorption parameters, whereas the coefficient a and the exponent b of the reduced scattering coefficient spectrum approximated by a power law function were estimated as the scattering parameters. The spectra of absorption and reduced scattering coefficients were reconstructed from the absorption and scattering parameters, and the spectral images of absorption and reduced scattering coefficients were then estimated. In order to confirm the feasibility of this method, we performed in vivo experiments on exposed rat brain. The estimated images of the absorption coefficients were dominated by the spectral characteristics of hemoglobin. The estimated spectral images of the reduced scattering coefficients had a broad scattering spectrum, exhibiting a larger magnitude at shorter wavelengths, corresponding to the typical spectrum of brain tissue published in the literature. The changes in the estimated absorption and scattering parameters during normoxia, hyperoxia, and anoxia indicate the potential applicability of the method by which to evaluate the pathophysiological conditions of in vivo brain due to the loss of tissue viability.

  12. Gender and age related expression of Oct-6--a POU III domain transcription factor, in the adult mouse brain.

    PubMed

    Ilia, Maria; Sugiyama, Yuka; Price, Jack

    2003-06-26

    Oct-6 is a POU III domain transcription factor whose primary role is thought to be developmental. It is expressed in embryonic stem cells, Schwann cells, and in neuronal subpopulations during telencephalic development. Its best characterised role is in Schwann cells where it is thought to regulate myelin specific gene expression. Expression of Oct-6 was recently discovered in neurons in post-mortem human schizophrenic specimens while being undetectable in matched controls. This study of human tissue contrasted in a number of regards with earlier studies of rodent brain, and questioned what we can consider to be normal adult expression of this gene. In this study, we have investigated Oct-6 expression via in situ hybridisation and Western blot analysis in normal adult female mice of different ages. We show that both RNA and protein levels of Oct-6 expression are highly sustained in the adult and aging cerebellum, whereas they are attenuated in the telencephalon by PW30 (postnatal week 30). These observations suggest that Oct-6 expression takes place in a sex and age dependent way. PMID:12782346

  13. Picture My Gender(s): Using Interactive Media to Engage Students in Theories of Gender Construction

    ERIC Educational Resources Information Center

    Sargent, Carey; Corse, Sarah M.

    2013-01-01

    We present an exercise on "doing gender" that uses digital media to create an opportunity for interactive learning. Students create photo essays on gender performances in everyday life and then present their photo essays to their peers. This exercise allows undergraduates to engage in "real-life" learning regarding the socially…

  14. GENDERED CHALLENGE, GENDERED RESPONSE

    PubMed Central

    KELLY, ERIN L.; AMMONS, SAMANTHA K.; CHERMACK, KELLY; MOEN, PHYLLIS

    2010-01-01

    This article integrates research on gendered organizations and the work-family interface to investigate an innovative workplace initiative, the Results-Only Work Environment (ROWE), implemented in the corporate headquarters of Best Buy, Inc. While flexible work policies common in other organizations “accommodate” individuals, this initiative attempts a broader and deeper critique of the organizational culture. We address two research questions: How does this initiative attempt to change the masculinized ideal worker norm? And what do women's and men's responses reveal about the persistent ways that gender structures work and family life? Data demonstrate the ideal worker norm is pervasive and powerful, even as employees begin critically examining expectations regarding work time that have historically privileged men. Employees' responses to ROWE are also gendered. Women (especially mothers) are more enthusiastic, while men are more cautious. Ambivalence about and resistance to change is expressed in different ways depending on gender and occupational status. PMID:20625518

  15. "Computer Games Can Get Your Brain Working": Student Experience and Perceptions of Digital Games in the Classroom

    ERIC Educational Resources Information Center

    Beavis, Catherine; Muspratt, Sandy; Thompson, Roberta

    2015-01-01

    There is considerable enthusiasm in many quarters for the incorporation of digital games into the classroom, and the capacity of games to engage and challenge players, present complex representations and experiences, foster collaborative learning, and promote deep learning. But while there is increasing research documenting the progress and…

  16. A 3-dimensional digital atlas of the ascending sensory and the descending motor systems in the pigeon brain.

    PubMed

    Güntürkün, Onur; Verhoye, Marleen; De Groof, Geert; Van der Linden, Annemie

    2013-01-01

    Pigeons are classic animal models for learning, memory, and cognition. The majority of the current understanding about avian neurobiology outside of the domain of the song system has been established using pigeons. Since MRI represents an increasingly relevant tool for comparative neuroscience, a 3-dimensional MRI-based atlas of the pigeon brain becomes essential. Using multiple imaging protocols, we delineated diverse ascending sensory and descending motor systems as well as the hippocampal formation. This pigeon brain atlas can easily be used to determine the stereotactic location of identified neural structures at any angle of the head. In addition, the atlas is useful to find the optimal angle of sectioning for slice experiments, stereotactic injections and electrophysiological recordings. This pigeon brain atlas is freely available for the scientific community. PMID:22367250

  17. Differences in Student Information and Communication Technology Literacy Based on Socio-Economic Status, Ethnicity, and Gender: Evidence of a Digital Divide in Florida Schools

    ERIC Educational Resources Information Center

    Ritzhaupt, Albert D.; Liu, Feng; Dawson, Kara; Barron, Ann E.

    2013-01-01

    This research examines student information and communication technology (ICT) literacy and its relationships to a student's socio-economic status (SES), gender, and ethnicity of middle school students. We recruited 5,990 students from 13 school districts across the state of Florida. Student participants completed the Student Tool for Technology…

  18. The Information Aged: Examination of University Students' Attitudes towards Personal Digital Assistants (PDAs) Usage in Terms of Gender, Age and School Variables

    ERIC Educational Resources Information Center

    Alzaidiyeen, Naser Jamil; Abdullah, Abdul Ghani Kanesan; Al-Shabatat, Ahmad Mohammad; Seedee, Rattana

    2011-01-01

    Recently, there has been a rabid development of new technology devices that were proved to have significant effects on education, one of which is known as Personal Digital Assistant (PDA). PDAs offer new possibilities for providing better learning experiences and more learning opportunities in the sector of higher education. A quantitative design…

  19. Postmortem examination of patient H.M.’s brain based on histological sectioning and digital 3D reconstruction

    NASA Astrophysics Data System (ADS)

    Annese, Jacopo; Schenker-Ahmed, Natalie M.; Bartsch, Hauke; Maechler, Paul; Sheh, Colleen; Thomas, Natasha; Kayano, Junya; Ghatan, Alexander; Bresler, Noah; Frosch, Matthew P.; Klaming, Ruth; Corkin, Suzanne

    2014-01-01

    Modern scientific knowledge of how memory functions are organized in the human brain originated from the case of Henry G. Molaison (H.M.), an epileptic patient whose amnesia ensued unexpectedly following a bilateral surgical ablation of medial temporal lobe structures, including the hippocampus. The neuroanatomical extent of the 1953 operation could not be assessed definitively during H.M.’s life. Here we describe the results of a procedure designed to reconstruct a microscopic anatomical model of the whole brain and conduct detailed 3D measurements in the medial temporal lobe region. This approach, combined with cellular-level imaging of stained histological slices, demonstrates a significant amount of residual hippocampal tissue with distinctive cytoarchitecture. Our study also reveals diffuse pathology in the deep white matter and a small, circumscribed lesion in the left orbitofrontal cortex. The findings constitute new evidence that may help elucidate the consequences of H.M.’s operation in the context of the brain’s overall pathology.

  20. Postmortem examination of patient H.M.’s brain based on histological sectioning and digital 3D reconstruction

    PubMed Central

    Annese, Jacopo; Schenker-Ahmed, Natalie M.; Bartsch, Hauke; Maechler, Paul; Sheh, Colleen; Thomas, Natasha; Kayano, Junya; Ghatan, Alexander; Bresler, Noah; Frosch, Matthew P.; Klaming, Ruth; Corkin, Suzanne

    2014-01-01

    Modern scientific knowledge of how memory functions are organized in the human brain originated from the case of Henry G. Molaison (H.M.), an epileptic patient whose amnesia ensued unexpectedly following a bilateral surgical ablation of medial temporal lobe structures, including the hippocampus. The neuroanatomical extent of the 1953 operation could not be assessed definitively during H.M.’s life. Here we describe the results of a procedure designed to reconstruct a microscopic anatomical model of the whole brain and conduct detailed 3D measurements in the medial temporal lobe region. This approach, combined with cellular-level imaging of stained histological slices, demonstrates a significant amount of residual hippocampal tissue with distinctive cytoarchitecture. Our study also reveals diffuse pathology in the deep white matter and a small, circumscribed lesion in the left orbitofrontal cortex. The findings constitute new evidence that may help elucidate the consequences of H.M.’s operation in the context of the brain’s overall pathology. PMID:24473151

  1. Cognitive state monitoring and the design of adaptive instruction in digital environments: lessons learned from cognitive workload assessment using a passive brain-computer interface approach.

    PubMed

    Gerjets, Peter; Walter, Carina; Rosenstiel, Wolfgang; Bogdan, Martin; Zander, Thorsten O

    2014-01-01

    According to Cognitive Load Theory (CLT), one of the crucial factors for successful learning is the type and amount of working-memory load (WML) learners experience while studying instructional materials. Optimal learning conditions are characterized by providing challenges for learners without inducing cognitive over- or underload. Thus, presenting instruction in a way that WML is constantly held within an optimal range with regard to learners' working-memory capacity might be a good method to provide these optimal conditions. The current paper elaborates how digital learning environments, which achieve this goal can be developed by combining approaches from Cognitive Psychology, Neuroscience, and Computer Science. One of the biggest obstacles that needs to be overcome is the lack of an unobtrusive method of continuously assessing learners' WML in real-time. We propose to solve this problem by applying passive Brain-Computer Interface (BCI) approaches to realistic learning scenarios in digital environments. In this paper we discuss the methodological and theoretical prospects and pitfalls of this approach based on results from the literature and from our own research. We present a strategy on how several inherent challenges of applying BCIs to WML and learning can be met by refining the psychological constructs behind WML, by exploring their neural signatures, by using these insights for sophisticated task designs, and by optimizing algorithms for analyzing electroencephalography (EEG) data. Based on this strategy we applied machine-learning algorithms for cross-task classifications of different levels of WML to tasks that involve studying realistic instructional materials. We obtained very promising results that yield several recommendations for future work. PMID:25538544

  2. Cognitive state monitoring and the design of adaptive instruction in digital environments: lessons learned from cognitive workload assessment using a passive brain-computer interface approach

    PubMed Central

    Gerjets, Peter; Walter, Carina; Rosenstiel, Wolfgang; Bogdan, Martin; Zander, Thorsten O.

    2014-01-01

    According to Cognitive Load Theory (CLT), one of the crucial factors for successful learning is the type and amount of working-memory load (WML) learners experience while studying instructional materials. Optimal learning conditions are characterized by providing challenges for learners without inducing cognitive over- or underload. Thus, presenting instruction in a way that WML is constantly held within an optimal range with regard to learners' working-memory capacity might be a good method to provide these optimal conditions. The current paper elaborates how digital learning environments, which achieve this goal can be developed by combining approaches from Cognitive Psychology, Neuroscience, and Computer Science. One of the biggest obstacles that needs to be overcome is the lack of an unobtrusive method of continuously assessing learners' WML in real-time. We propose to solve this problem by applying passive Brain-Computer Interface (BCI) approaches to realistic learning scenarios in digital environments. In this paper we discuss the methodological and theoretical prospects and pitfalls of this approach based on results from the literature and from our own research. We present a strategy on how several inherent challenges of applying BCIs to WML and learning can be met by refining the psychological constructs behind WML, by exploring their neural signatures, by using these insights for sophisticated task designs, and by optimizing algorithms for analyzing electroencephalography (EEG) data. Based on this strategy we applied machine-learning algorithms for cross-task classifications of different levels of WML to tasks that involve studying realistic instructional materials. We obtained very promising results that yield several recommendations for future work. PMID:25538544

  3. Bioethics' gender.

    PubMed

    Lindemann, Hilde

    2006-01-01

    I argue that the field of bioethics is gendered feminine, but that the methods it uses to resist this gender identity pose real harm to actual women. Starting with an explanation of what I take 'gender' to be, I enumerate four drawbacks to being gendered feminine. I then argue that bioethics suffers from three of the same four drawbacks. I show how the field escapes the fourth disadvantage by adopting a masculine persona that inflicts damage on women, and conclude by urging bioethicists to reflect on their complicity in abusive power systems such as gender, race and class. PMID:16500829

  4. Automatic testing and assessment of neuroanatomy using a digital brain atlas: method and development of computer- and mobile-based applications.

    PubMed

    Nowinski, Wieslaw L; Thirunavuukarasuu, Arumugam; Ananthasubramaniam, Anand; Chua, Beng Choon; Qian, Guoyu; Nowinska, Natalia G; Marchenko, Yevgen; Volkau, Ihar

    2009-10-01

    Preparation of tests and student's assessment by the instructor are time consuming. We address these two tasks in neuroanatomy education by employing a digital media application with a three-dimensional (3D), interactive, fully segmented, and labeled brain atlas. The anatomical and vascular models in the atlas are linked to Terminologia Anatomica. Because the cerebral models are fully segmented and labeled, our approach enables automatic and random atlas-derived generation of questions to test location and naming of cerebral structures. This is done in four steps: test individualization by the instructor, test taking by the students at their convenience, automatic student assessment by the application, and communication of the individual assessment to the instructor. A computer-based application with an interactive 3D atlas and a preliminary mobile-based application were developed to realize this approach. The application works in two test modes: instructor and student. In the instructor mode, the instructor customizes the test by setting the scope of testing and student performance criteria, which takes a few seconds. In the student mode, the student is tested and automatically assessed. Self-testing is also feasible at any time and pace. Our approach is automatic both with respect to test generation and student assessment. It is also objective, rapid, and customizable. We believe that this approach is novel from computer-based, mobile-based, and atlas-assisted standpoints. PMID:19743409

  5. The Myth of Pink and Blue Brains

    ERIC Educational Resources Information Center

    Eliot, Lise

    2010-01-01

    Eliot, a neuroscientist who has analyzed gender differences in children's brains, asserts that--contrary to the widely held idea that boys' and girls' brains are hardwired differently--few differences exist in the neural structures and neurochemistry of boys' and girls' brains. Actual ability differences between the genders are quite small as…

  6. "Girls Have More of an Educational Brain": A Qualitative Exploration of the Gender Gap in Educational Attainment among Black Bermudian Adolescents

    ERIC Educational Resources Information Center

    Jethwani, Monique M.

    2015-01-01

    Although Black boys throughout the African diaspora are dropping out of high school in alarming rates, little is known about how educational identity and attainment is shaped by the intersection of race and gender in the high school environment. Utilizing an ecological and intersectionality theoretical lens, this study draws on data gleaned from…

  7. Prosocial behavior and gender

    PubMed Central

    Espinosa, María Paz; Kovářík, Jaromír

    2015-01-01

    This study revisits different experimental data sets that explore social behavior in economic games and uncovers that many treatment effects may be gender-specific. In general, men and women do not differ in “neutral” baselines. However, we find that social framing tends to reinforce prosocial behavior in women but not men, whereas encouraging reflection decreases the prosociality of males but not females. The treatment effects are sometimes statistically different across genders and sometimes not but never go in the opposite direction. These findings suggest that (i) the social behavior of both sexes is malleable but each gender responds to different aspects of the social context; and (ii) gender differences observed in some studies might be the result of particular features of the experimental design. Our results contribute to the literature on prosocial behavior and may improve our understanding of the origins of human prosociality. We discuss the possible link between the observed differential treatment effects across genders and the differing male and female brain network connectivity, documented in recent neural studies. PMID:25926783

  8. Diversity, Disability, and Geographic Digital Divide

    ERIC Educational Resources Information Center

    Sumari, Melati; Carr, Erika; Ndebe-Ngovo, Manjerngie

    2006-01-01

    The phenomenon called digital divide was the focus of this paper. Diversity, disability, and geographical digital divide were relevant to this collaborative project. An extensive review of the literature was conducted for the completion of this project. The evidence for the digital divide in terms of race, level of education, and gender in the…

  9. Gender determination using cheiloscopy

    PubMed Central

    Padmavathi, B. N.; Makkad, Ramanpal Singh; Rajan, S. Y.; Kolli, Gopi Krishna

    2013-01-01

    Background: Although lip prints have been used as an evidence for human identification in forensic science, there exists a doubt about its role in gender determination. Aims: The present study was designed for documenting common patterns, as well as their variation in the study population, with objective of evaluating uniqueness of the lip print pattern among the study population, as well as to evaluate the possibility of gender determination. Study Design: Two hundred and thirty five lip prints were collected from volunteers among out patients of Darshan Dental College and Hospital, as well as community dental care camps of rural areas around Udaipur. Materials and Methods: Lip prints were recorded with transparent overlay and transferred on to a bond paper. It was then photographed using a Canon EOS 55OD 16 mega pixel digital camera. Software Picasa 3.6 and Microsoft Picture Manager were used to digitally enhance the quality and magnify the image bearing the groove pattern. Lip prints were later analyzed. Statistical Analysis: Pearson chi square test was adopted for statistical analysis and probability (P value) was calculated. Conclusion: In our study, none of the lip prints were identical, thus confirming the role of lip prints in individual identification. Dots, reticular and complex patterns were significant in gender determination. PMID:24255561

  10. Gender through Their Lenses: A Film of Students' Images

    ERIC Educational Resources Information Center

    Miller, Carol D.; Seitz, Mark James

    2014-01-01

    Students in a Sociology of Gender class were each required to provide five digital photos of something they have seen in their worlds that represents beliefs or behaviors related to gender. The photos were organized into themes related to assigned readings on gender and work, family, sexuality, health, education, and more. A short film using their…

  11. Gender Differences in Students' Mathematics Game Playing

    ERIC Educational Resources Information Center

    Lowrie, Tom; Jorgensen, Robyn

    2011-01-01

    The investigation monitored the digital game-playing behaviours of 428 primary-aged students (aged 10-12 years). Chi-square analysis revealed that boys tend to spend more time playing digital games than girls while boys and girls play quite different game genres. Subsequent analysis revealed statistically significant gender differences in terms of…

  12. Gender Imputation

    ERIC Educational Resources Information Center

    National Student Clearinghouse, 2013

    2013-01-01

    In late 2007, the National Student Clearinghouse (NSC) expanded its Enrollment Reporting service to include several additional data elements (commonly referred to as the "A2" or "expanded" data elements). One of these expanded data elements is student gender. Although gender is potentially important to a number of research…

  13. Gender Development

    ERIC Educational Resources Information Center

    Owen Blakemore, Judith E.; Berenbaum, Sheri A.; Liben, Lynn S.

    2008-01-01

    This new text offers a unique developmental focus on gender. Gender development is examined from infancy through adolescence, integrating biological, socialization, and cognitive perspectives. The book's current empirical focus is complemented by a lively and readable style that includes anecdotes about children's everyday experiences. The book's…

  14. Gender Advertisements.

    ERIC Educational Resources Information Center

    Goffman, Erving

    A heavily illustrated discussion of the ways in which men and women are portrayed in advertisements is presented. The three essays which precede the 56 pages of illustrations discuss gender expressions, characteristics of public and private pictures, and gender commercials. The author notes that advertisements do not depict how men and women…

  15. Gender Fictions.

    ERIC Educational Resources Information Center

    Lee, Lesley

    1992-01-01

    Reviews and compares "Gender and Mathematics" edited by Leone Burton and Valerie Walkerdine's book "Schoolgirl Fictions" on proposed truths related to gender issues in mathematics. Issues include (1) attention given to boys and girls in mathematics class; (2) the effects of noncompetitive classroom environments; and (3) sex differences in…

  16. Sex steroids and variants of gender identity.

    PubMed

    Meyer-Bahlburg, Heino F L

    2013-09-01

    This article summarizes for the practicing endocrinologist the current literature on the psychobiology of the development of gender identity and its variants in individuals with disorders of sex development (DSD) or with non-DSD transgenderism. Gender reassignment remains the treatment of choice for strong and persistent gender dysphoria in both categories, but more research is needed on the short-term and long-term effects of puberty-suppressing medications and cross-sex hormones on brain and behavior. PMID:24011879

  17. Neuroimaging studies in people with gender incongruence.

    PubMed

    Kreukels, Baudewijntje P C; Guillamon, Antonio

    2016-01-01

    The current review gives an overview of brain studies in transgender people. First, we describe studies into the aetiology of feelings of gender incongruence, primarily addressing the sexual differentiation hypothesis: does the brain of transgender individuals resemble that of their natal sex, or that of their experienced gender? Findings from neuroimaging studies focusing on brain structure suggest that the brain phenotypes of trans women (MtF) and trans men (FtM) differ in various ways from control men and women with feminine, masculine, demasculinized and defeminized features. The brain phenotypes of people with feelings of gender incongruence may help us to figure out whether sex differentiation of the brain is atypical in these individuals, and shed light on gender identity development. Task-related imaging studies may show whether brain activation and task performance in transgender people is sex-atypical. Second, we review studies that evaluate the effects of cross-sex hormone treatment on the brain. This type of research provides knowledge on how changes in sex hormone levels may affect brain structure and function. PMID:26766406

  18. Gender Segregation: Separate but Effective?

    ERIC Educational Resources Information Center

    Holthouse, David

    2010-01-01

    In 2002, only 11 public schools in the United States had gender-segregated classrooms. As of December 2009, there were more than 550. The movement is based on the hypothesis that hard-wired differences in the ways that male and female brains develop and function in childhood through adolescence require classrooms in which boys and girls are not…

  19. Users Views about the Usability of Digital Libraries

    ERIC Educational Resources Information Center

    Koohang, Alex; Ondracek, James

    2005-01-01

    This study examined users' views about the usability of digital libraries' current and perceived importance. Age, gender, prior experience with the Internet, college status, and digital library proficiency are the independent variables. Users' current views about the usability of digital libraries and users perceived importance of digital library…

  20. Gender Development.

    ERIC Educational Resources Information Center

    Golombok, Susan; Fivush, Robyn

    In spite of the loosening ties between reproductive and social roles, the worlds of men and women and boys and girls, are clearly not the same. There is much more to being female or male than the potential to mother or father a child. Gender development does not simply depend on children's relationship with their parents: it results from a complex…

  1. Brain-derived neurotrophic factor serum levels in genetically isolated populations: gender-specific association with anxiety disorder subtypes but not with anxiety levels or Val66Met polymorphism.

    PubMed

    Carlino, Davide; Francavilla, Ruggiero; Baj, Gabriele; Kulak, Karolina; d'Adamo, Pio; Ulivi, Sheila; Cappellani, Stefania; Gasparini, Paolo; Tongiorgi, Enrico

    2015-01-01

    Anxiety disorders (ADs) are disabling chronic disorders with exaggerated behavioral response to threats. This study was aimed at testing the hypothesis that ADs may be associated with reduced neurotrophic activity, particularly of Brain-derived neurotrophic factor (BDNF), and determining possible effects of genetics on serum BDNF concentrations. In 672 adult subjects from six isolated villages in North-Eastern Italy with high inbreeding, we determined serum BDNF levels and identified subjects with different ADs subtypes such as Social and Specific Phobias (PHSOC, PHSP), Generalized Anxiety Disorder (GAD), and Panic Disorder (PAD). Analysis of the population as a whole or individual village showed no significant correlation between serum BDNF levels and Val66Met polymorphism and no association with anxiety levels. Stratification of subjects highlighted a significant decrease in serum BDNF in females with GAD and males with PHSP. This study indicates low heritability and absence of any impact of the Val66Met polymorphism on circulating concentrations of BDNF. Our results show that BDNF is not a general biomarker of anxiety but serum BDNF levels correlate in a gender-specific manner with ADs subtypes. PMID:26539329

  2. Brain-derived neurotrophic factor serum levels in genetically isolated populations: gender-specific association with anxiety disorder subtypes but not with anxiety levels or Val66Met polymorphism

    PubMed Central

    Carlino, Davide; Francavilla, Ruggiero; Baj, Gabriele; Kulak, Karolina; d’Adamo, Pio; Ulivi, Sheila; Cappellani, Stefania; Gasparini, Paolo

    2015-01-01

    Anxiety disorders (ADs) are disabling chronic disorders with exaggerated behavioral response to threats. This study was aimed at testing the hypothesis that ADs may be associated with reduced neurotrophic activity, particularly of Brain-derived neurotrophic factor (BDNF), and determining possible effects of genetics on serum BDNF concentrations. In 672 adult subjects from six isolated villages in North-Eastern Italy with high inbreeding, we determined serum BDNF levels and identified subjects with different ADs subtypes such as Social and Specific Phobias (PHSOC, PHSP), Generalized Anxiety Disorder (GAD), and Panic Disorder (PAD). Analysis of the population as a whole or individual village showed no significant correlation between serum BDNF levels and Val66Met polymorphism and no association with anxiety levels. Stratification of subjects highlighted a significant decrease in serum BDNF in females with GAD and males with PHSP. This study indicates low heritability and absence of any impact of the Val66Met polymorphism on circulating concentrations of BDNF. Our results show that BDNF is not a general biomarker of anxiety but serum BDNF levels correlate in a gender-specific manner with ADs subtypes. PMID:26539329

  3. Digital Libraries.

    ERIC Educational Resources Information Center

    Fox, Edward A.; Urs, Shalini R.

    2002-01-01

    Provides an overview of digital libraries research, practice, and literature. Highlights include new technologies; redefining roles; historical background; trends; creating digital content, including conversion; metadata; organizing digital resources; services; access; information retrieval; searching; natural language processing; visualization;…

  4. The numerology of gender: gendered perceptions of even and odd numbers

    PubMed Central

    Wilkie, James E. B.; Bodenhausen, Galen V.

    2015-01-01

    Do numbers have gender? Wilkie and Bodenhausen (2012) examined this issue in a series of experiments on perceived gender. They examined the perceived gender of baby faces and foreign names. Arbitrary numbers presented with these faces and names influenced their perceived gender. Specifically, odd numbers connoted masculinity, while even numbers connoted femininity. In two new studies (total N = 315), we further examined the gendering of numbers. The first study examined explicit ratings of 1-digit numbers. We confirmed that odd numbers seemed masculine while even numbers seemed feminine. Although both men and women showed this pattern, it was more pronounced among women. We also examined whether this pattern holds for automatic as well as deliberated reactions. Results of an Implicit Association Test showed that it did, but only among the women. The implicit and explicit patterns of numerical gender ascription were moderately correlated. The second study examined explicit perceptions of 2-digit numbers. Again, women viewed odd numbers as more masculine and less feminine than even numbers. However, men viewed 2-digit numbers as relatively masculine, regardless of whether they were even or odd. These results indicate that women and men impute gender to numbers in different ways and to different extents. We discuss possible implications for understanding how people relate to and are influenced by numbers in a variety of real-life contexts. PMID:26113839

  5. The numerology of gender: gendered perceptions of even and odd numbers.

    PubMed

    Wilkie, James E B; Bodenhausen, Galen V

    2015-01-01

    Do numbers have gender? Wilkie and Bodenhausen (2012) examined this issue in a series of experiments on perceived gender. They examined the perceived gender of baby faces and foreign names. Arbitrary numbers presented with these faces and names influenced their perceived gender. Specifically, odd numbers connoted masculinity, while even numbers connoted femininity. In two new studies (total N = 315), we further examined the gendering of numbers. The first study examined explicit ratings of 1-digit numbers. We confirmed that odd numbers seemed masculine while even numbers seemed feminine. Although both men and women showed this pattern, it was more pronounced among women. We also examined whether this pattern holds for automatic as well as deliberated reactions. Results of an Implicit Association Test showed that it did, but only among the women. The implicit and explicit patterns of numerical gender ascription were moderately correlated. The second study examined explicit perceptions of 2-digit numbers. Again, women viewed odd numbers as more masculine and less feminine than even numbers. However, men viewed 2-digit numbers as relatively masculine, regardless of whether they were even or odd. These results indicate that women and men impute gender to numbers in different ways and to different extents. We discuss possible implications for understanding how people relate to and are influenced by numbers in a variety of real-life contexts. PMID:26113839

  6. Gender differences in regional cerebral blood flow

    SciTech Connect

    Gur, R.E.; Gur, R.C. )

    1990-01-01

    Gender differences have been noted in neurobehavioral studies. The 133xenon inhalation method for measuring regional cerebral blood flow (rCBF) can contribute to the understanding of the neural basis of gender differences in brain function. Few studies have examined gender differences in rCBF. In studies of normal subjects, women have higher rates of CBF than men, and this is related to age. Usually by the sixth decade men and women have similar flow rates. Fewer studies on rCBF in schizophrenia have examined sex differences. The pattern of higher flows for females maintains, but its correlates with gender differences in clinical as well as other parameters of brain function remain to be examined.

  7. Schizophrenia and the influence of male gender.

    PubMed

    Remington, G; Seeman, M V

    2015-12-01

    Adolescent boys are the demographic group most likely to receive a diagnosis of schizophrenia. Before adulthood, boys accumulate more potential brain hazards than girls, and this may predispose them to disordered neurodevelopment during adolescence. Hormonal and immune gender differences that emerge at this time likely play an additional and significant role. Very recently, gender differences can be examined even before the onset of full-blown illness, in individuals at "clinically high risk." PMID:26260896

  8. Digital Preservation.

    ERIC Educational Resources Information Center

    Yakel, Elizabeth

    2001-01-01

    Reviews research on digital preservation issues, including born-digital and digitally recreated documents. Discusses electronic records research; metadata and other standards; electronic mail; Web-based documents; moving images media; selection of materials for digitization, including primary sources; administrative issues; media stability…

  9. Determinant factors of gender identity: a commentary.

    PubMed

    Liao, Lih-Mei; Audi, Laura; Magritte, Ellie; Meyer-Bahlburg, Heino F L; Quigley, Charmian A

    2012-12-01

    Paediatric specialists involved in the care of children with disorders of sex development may be expected to provide straightforward answers to questions concerning the "true sex" of a child, reflecting common perceptions of sex/gender as an immutable binary biological reality. This article highlights how much more broad and complex the topic of gender identity and its development is. Many theories have been put forward to advance knowledge of gender identity. Against the breadth and depth of this vast topic, the current overview is inevitably incomplete. It begins by arguing for a more consistent use of 'sex' and 'gender'. It considers in turn three influential theoretical frameworks that lend themselves to empirical research. These are: 1) the role of the brain; 2) the role of socialisation; and 3) multi-dimensional gender development. The article ends by suggesting potentially fruitful questions and areas for future research. PMID:23158728

  10. Alzheimer, mitochondria and gender.

    PubMed

    Grimm, Amandine; Mensah-Nyagan, Ayikoe Guy; Eckert, Anne

    2016-08-01

    Epidemiological studies revealed that two-thirds of Alzheimer's disease (AD) patients are women and the drop of sex steroid hormones after the menopause has been proposed to be one risk factor in AD. Similarly, the decrease of circulating testosterone levels with aging may also increase the risk of AD in men. Studies attest the neuroprotective effects of sex hormones in animal models of AD, but clinical trial data remain controversial. Here, we discuss the implication of mitochondria in gender differences observed in AD patients and animal models of AD. We summarize the role of mitochondria in aging and AD, pointing to the potential correlation between the loss of sex hormones and changes in the brain redox status. We discuss the protective effects of the sex hormones, estradiol, progesterone and testosterone with a specific focus on mitochondrial dysfunction in AD. The understanding of pathological processes linking the loss of sex hormones with mitochondrial dysfunction and mechanisms that initiate the disease onset may open new avenues for the development of gender-specific therapeutic approaches. PMID:27139022

  11. Towards a comprehensive atlas of cortical connections in a primate brain: Mapping tracer injection studies of the common marmoset into a reference digital template.

    PubMed

    Majka, Piotr; Chaplin, Tristan A; Yu, Hsin-Hao; Tolpygo, Alexander; Mitra, Partha P; Wójcik, Daniel K; Rosa, Marcello G P

    2016-08-01

    The marmoset is an emerging animal model for large-scale attempts to understand primate brain connectivity, but achieving this aim requires the development and validation of procedures for normalization and integration of results from many neuroanatomical experiments. Here we describe a computational pipeline for coregistration of retrograde tracing data on connections of cortical areas into a 3D marmoset brain template, generated from Nissl-stained sections. The procedure results in a series of spatial transformations that are applied to the coordinates of labeled neurons in the different cases, bringing them into common stereotaxic space. We applied this procedure to 17 injections, placed in the frontal lobe of nine marmosets as part of earlier studies. Visualizations of cortical patterns of connections revealed by these injections are supplied as Supplementary Materials. Comparison between the results of the automated and human-based processing of these cases reveals that the centers of injection sites can be reconstructed, on average, to within 0.6 mm of coordinates estimated by an experienced neuroanatomist. Moreover, cell counts obtained in different areas by the automated approach are highly correlated (r = 0.83) with those obtained by an expert, who examined in detail histological sections for each individual. The present procedure enables comparison and visualization of large datasets, which in turn opens the way for integration and analysis of results from many animals. Its versatility, including applicability to archival materials, may reduce the number of additional experiments required to produce the first detailed cortical connectome of a primate brain. J. Comp. Neurol. 524:2161-2181, 2016. © 2016 The Authors The Journal of Comparative Neurology Published by Wiley Periodicals, Inc. PMID:27099164

  12. Digital Citizenship

    ERIC Educational Resources Information Center

    Isman, Aytekin; Canan Gungoren, Ozlem

    2014-01-01

    Era in which we live is known and referred as digital age.In this age technology is rapidly changed and developed. In light of these technological advances in 21st century, schools have the responsibility of training "digital citizen" as well as a good citizen. Digital citizens must have extensive skills, knowledge, Internet and …

  13. Can Neuroscience Construct a Literate Gendered Culture?

    ERIC Educational Resources Information Center

    Whitehead, David

    2011-01-01

    The construction of boys as a gendered culture is not usually associated with neuroscience. Exceptions are publications and presentations by consultants on boys' education who adopt a "brain-based" perspective. From a neuroscience perspective, my analysis indicates the selective use of primary neuroscience research to construct and perpetuate…

  14. Digital Natives or Digital Tribes?

    ERIC Educational Resources Information Center

    Watson, Ian Robert

    2013-01-01

    This research builds upon the discourse surrounding digital natives. A literature review into the digital native phenomena was undertaken and found that researchers are beginning to identify the digital native as not one cohesive group but of individuals influenced by other factors. Primary research by means of questionnaire survey of technologies…

  15. Brain Science, Brain Fiction.

    ERIC Educational Resources Information Center

    Bruer, John T.

    1998-01-01

    Three big ideas from brain science have arisen during the past 20 to 30 years: neural connections form rapidly early in life; critical periods occur in development; and enriched environments profoundly affect brain development during the early years. Current brain research has little to offer educational practice or policy. (10 references) (MLH)

  16. Silicon Brains

    NASA Astrophysics Data System (ADS)

    Hoefflinger, Bernd

    Beyond the digital neural networks of Chap. 16, the more radical mapping of brain-like structures and processes into VLSI substrates has been pioneered by Carver Mead more than 30 years ago [1]. The basic idea was to exploit the massive parallelism of such circuits and to create low-power and fault-tolerant information-processing systems. Neuromorphic engineering has recently seen a revival with the availability of deep-submicron CMOS technology, which allows for the construction of very-large-scale mixed-signal systems combining local analog processing in neuronal cells with binary signalling via action potentials. Modern implementations are able to reach the complexity-scale of large functional units of the human brain, and they feature the ability to learn by plasticity mechanisms found in neuroscience. Combined with high-performance programmable logic and elaborate software tools, such systems are currently evolving into user-configurable non-von-Neumann computing systems, which can be used to implement and test novel computational paradigms. The chapter introduces basic properties of biological brains with up to 200 Billion neurons and their 1014 synapses, where action on a synapse takes ˜10 ms and involves an energy of ˜10 fJ. We outline 10x programs on neuromorphic electronic systems in Europe and the USA, which are intended to integrate 108 neurons and 1012 synapses, the level of a cat's brain, in a volume of 1 L and with a power dissipation <1 kW. For a balanced view on intelligence, we references Hawkins' view to first perceive the task and then design an intelligent technical response.

  17. Nature, nurture, and core gender identity.

    PubMed

    Robbins, M

    1996-01-01

    Literature about gender differences and their possible origins, and contemporary psychoanalytic formulations of gender, is reviewed. There is a broad consensus among investigators from different fields, and among psychoanalysts of different theoretical persuasions, that the modal female personality tends to be more sociocentric, and the modal male personality more self-centric. These modal personality differences may be qualitative rather than quantitative. The concept of core gender identity, which articulates the psychological root of these differences, is reexamined in the light of contemporary research into constitutional differences in the organization and activation of the brain, and an interactional model of core gender identity as a dynamic evolving phenomenon over the course of the life cycle is proposed. PMID:9170059

  18. Gender Differences in Neurodevelopment and Epigenetics

    PubMed Central

    Chung, Wilson C.J.; Auger, Anthony P.

    2013-01-01

    Summary The concept that the brain differs in make-up between males and females is not new. For example, it is well-established that anatomists in the nineteenth century found sex differences in human brain weight. The importance of sex differences in the organization of the brain cannot be overstated as they may directly affect cognitive functions, such as verbal skills and visio-spatial tasks in a sex-dependent fashion. Moreover, the incidence of neurological and psychiatric diseases is also highly dependent on sex. These clinical observations reiterate the importance that gender must be taken into account as a relevant possible contributing factor in order to understand the pathogenesis of neurological and psychiatric disorders. Gender-dependent differentiation of the brain has been detected at every levels of organization: morphological, neurochemical, and functional, and have been shown to be primarily controlled by sex differences in gonadal steroid hormone levels during perinatal development. In this review, we discuss how the gonadal steroid hormone testosterone and its metabolites, affect downstream signaling cascades, including gonadal steroid receptor activation, and epigenetic events in order to differentiate the brain in a gender-dependent fashion. PMID:23503727

  19. Gender Differences in Learning Styles: Nurturing a Gender and Style Sensitive Computer Science Classroom

    ERIC Educational Resources Information Center

    Lau, Wilfred Wing Fat; Yuen, Allan Hoi Kau

    2010-01-01

    The gender digital divide has been widely discussed and researched over the years. Previous studies have focused on a number of factors such as computer attitude, computer anxiety, computer self-efficacy, and computer experience. This study empirically tested the sensitivity of a learning style instrument, the "Gregorc Style Delineator" (GSD), to…

  20. Implicit interactions between number and space in digit-color synesthesia.

    PubMed

    Niessen, Eva; Fink, Gereon R; Schweitzer, Lisa; Kluender, Nora; Weiss, Peter H

    2015-03-01

    In digit-color synesthesia, a variant of grapheme-color synesthesia, digits trigger an additional color percept. Recent work on number processing in synesthesia suggests that colors can implicitly elicit numerical representations in digit-color synesthetes implying that synesthesia is bidirectional. Furthermore, morphometric investigations revealed structural differences in the parietal cortex of grapheme-color synesthetes, i.e., in the brain region where interactions between number and space occur in non-synesthetic subjects. Based upon these previous findings, we here examined whether implicitly evoked numerical representations interact with spatial representations in synesthesia in such a way that even a non-numerical, visuo-spatial task (here: line bisection) is modulated, i.e., whether synesthetes exhibit a systematic bisection bias for colored lines. Thirteen digit-color synesthetes were asked to bisect two sets of lines which were colored in their individual synesthetic colors associated with a small or a large digit, respectively. For all colored line stimuli combined, digit-color synesthetes showed--like control subjects (n = 13, matched for age, gender, IQ and handedness)--a pseudo-neglect when bisecting colored lines. Measuring the color-induced change of the bisection bias (i.e., comparing the biases when bisecting lines colored according to a small number vs those lines corresponding to a large number) revealed that only digit-color synesthetes were significantly influenced by line color. The results provide further evidence for the bidirectional nature of synesthesia and support the concept of a mental number line. In addition, they extend previous reports on bidirectionality in synesthesia by showing that even non-numerical, visuo-spatial performance can be modulated by implicit bidirectional processes. PMID:25498947

  1. Queering gender: anima/animus and the paradigm of emergence.

    PubMed

    McKenzie, Susan

    2006-06-01

    An exploration into the world of the queer others of gender and sexuality moves us beyond the binary opposition of male/masculinity and female/femininity in our understanding of gender and expands the meaning of gender and sexuality for all humans. A revision of Jungian gender theory that embraces all genders and sexualities is needed not only to inform our clinical work but also to allow us to bring Jungian thought to contemporary gender theory and to cultural struggles such as gay marriage. The cognitive and developmental neurosciences are increasingly focused on the importance of body biology and embodied experience to the emergence of mind. In my exploration of gender I ask how gender comes to be experienced in a developing body and how those embodied gender feelings elaborate into a conscious category in the mind, a gender position. My understanding of emergent mind theory suggests that one's sense of gender, like other aspects of the mind, emerges very early in development from a self-organizing process involving an individual's particular body biology, the brain, and cultural environment. Gendered feeling, from this perspective, would be an emergent aspect of mind and not an archetypal inheritance, and the experiencing body would be key to gender emergence. A revised Jungian gender theory would transcend some of the limitations of Jung's anima/animus (A/A) gender thinking allowing us to contribute to contemporary gender theory in the spirit of another Jung; the Jung of the symbolic, the mythic, and the subtle body. This is the Jung who invites us to the medial place of the soul, bridging the realm of the physical body and the realm of the spirit. PMID:16712684

  2. Large scale digital atlases in neuroscience

    NASA Astrophysics Data System (ADS)

    Hawrylycz, M.; Feng, D.; Lau, C.; Kuan, C.; Miller, J.; Dang, C.; Ng, L.

    2014-03-01

    Imaging in neuroscience has revolutionized our current understanding of brain structure, architecture and increasingly its function. Many characteristics of morphology, cell type, and neuronal circuitry have been elucidated through methods of neuroimaging. Combining this data in a meaningful, standardized, and accessible manner is the scope and goal of the digital brain atlas. Digital brain atlases are used today in neuroscience to characterize the spatial organization of neuronal structures, for planning and guidance during neurosurgery, and as a reference for interpreting other data modalities such as gene expression and connectivity data. The field of digital atlases is extensive and in addition to atlases of the human includes high quality brain atlases of the mouse, rat, rhesus macaque, and other model organisms. Using techniques based on histology, structural and functional magnetic resonance imaging as well as gene expression data, modern digital atlases use probabilistic and multimodal techniques, as well as sophisticated visualization software to form an integrated product. Toward this goal, brain atlases form a common coordinate framework for summarizing, accessing, and organizing this knowledge and will undoubtedly remain a key technology in neuroscience in the future. Since the development of its flagship project of a genome wide image-based atlas of the mouse brain, the Allen Institute for Brain Science has used imaging as a primary data modality for many of its large scale atlas projects. We present an overview of Allen Institute digital atlases in neuroscience, with a focus on the challenges and opportunities for image processing and computation.

  3. Radiographic evaluation of mandibular ramus for gender estimation: Retrospective study

    PubMed Central

    Damera, Ajit; Mohanalakhsmi, Jonnala; Yellarthi, Pavan Kumar; Rezwana, Begum Mohammed

    2016-01-01

    Background and Aims: Gender estimation is a very important part of a study in the field of anthropology and forensic sciences. In the skeleton, gender estimation is the first step of the identification process as subsequent methods for age and stature estimation are sex-dependent. Skeletal components such as the pelvis and skull are investigated for gender estimation and the mandible is a practical element to analyze sexual dimorphism in fragmented bones. The aim of the present study is to measure, compare, and evaluate various measurements of the mandibular ramus, observed in digital orthopantomographs and also to assess the usefulness of the mandibular ramus as an aid in gender estimation. Materials and Methods: A radiographic retrospective study was conducted using 80 digital orthopantomographs to measure, compare, and evaluate the measurements of the mandibular ramus such as maximum ramus breadth, maximum ramus height, and coronoid heightusing Planmeca ProMax® digital machine to assess the usefulness of mandibular measurements in gender estimation. Results: Descriptive statistics of various measurements and associated univariate F ratios for both the sexes were determined. Four variables were significant predictor in classifying a given sample (P < 0.001). The F-statistic values indicated that measurements expressing the greatest sexual dimorphism were noticed in the maximum ramus height. Conclusion: Mandibular ramus can be considered as a valuable tool in gender estimation and the most reliable measurements were obtained of linear objects in the horizontal plane by digital panoramic imaging.

  4. Brain herniation

    MedlinePlus

    ... herniation; Uncal herniation; Subfalcine herniation; Tonsillar herniation; Herniation - brain ... Brain herniation occurs when something inside the skull produces pressure that moves brain tissues. This is most ...

  5. Digital metamaterials

    NASA Astrophysics Data System (ADS)

    Della Giovampaola, Cristian; Engheta, Nader

    2014-12-01

    Balancing complexity and simplicity has played an important role in the development of many fields in science and engineering. One of the well-known and powerful examples of such balance can be found in Boolean algebra and its impact on the birth of digital electronics and the digital information age. The simplicity of using only two numbers, ‘0’ and ‘1’, in a binary system for describing an arbitrary quantity made the fields of digital electronics and digital signal processing powerful and ubiquitous. Here, inspired by the binary concept, we propose to develop the notion of digital metamaterials. Specifically, we investigate how one can synthesize an electromagnetic metamaterial with a desired permittivity, using as building blocks only two elemental materials, which we call ‘metamaterial bits’, with two distinct permittivity functions. We demonstrate, analytically and numerically, how proper spatial mixtures of such metamaterial bits lead to elemental ‘metamaterial bytes’ with effective material parameters that are different from the parameters of the metamaterial bits. We then apply this methodology to several design examples of optical elements, such as digital convex lenses, flat graded-index digital lenses, digital constructs for epsilon-near-zero (ENZ) supercoupling and digital hyperlenses, thus highlighting the power and simplicity of the methodology.

  6. Digital metamaterials.

    PubMed

    Della Giovampaola, Cristian; Engheta, Nader

    2014-12-01

    Balancing complexity and simplicity has played an important role in the development of many fields in science and engineering. One of the well-known and powerful examples of such balance can be found in Boolean algebra and its impact on the birth of digital electronics and the digital information age. The simplicity of using only two numbers, '0' and '1', in a binary system for describing an arbitrary quantity made the fields of digital electronics and digital signal processing powerful and ubiquitous. Here, inspired by the binary concept, we propose to develop the notion of digital metamaterials. Specifically, we investigate how one can synthesize an electromagnetic metamaterial with a desired permittivity, using as building blocks only two elemental materials, which we call 'metamaterial bits', with two distinct permittivity functions. We demonstrate, analytically and numerically, how proper spatial mixtures of such metamaterial bits lead to elemental 'metamaterial bytes' with effective material parameters that are different from the parameters of the metamaterial bits. We then apply this methodology to several design examples of optical elements, such as digital convex lenses, flat graded-index digital lenses, digital constructs for epsilon-near-zero (ENZ) supercoupling and digital hyperlenses, thus highlighting the power and simplicity of the methodology. PMID:25218061

  7. Digital Opportunity

    ERIC Educational Resources Information Center

    Azzam, Amy M.

    2006-01-01

    This article details the content of a recently released report from the Children's Partnership titled "Measuring Digital Opportunity for America's Children: Where We Stand and Where We Go From Here". On the basis of 40 indicators, the report's Digital Opportunity Measuring Stick showed how U.S. children and young adults use information and…

  8. Digital TMI

    NASA Technical Reports Server (NTRS)

    Rios, Joseph

    2012-01-01

    Presenting the current status of the Digital TMI project to visiting members of the FAA Command Center. Digital TMI is an effort to store national-level traffic management initiatives in a standards-compliant manner. Work is funded by the FAA.

  9. Digital Discrimination

    ERIC Educational Resources Information Center

    Blansett, Jim

    2008-01-01

    In recent years, the Internet has become a digital commons of commerce and education. However, accessibility standards have often been overlooked online, and the digital equivalents to curb-cuts and other physical accommodations have only rarely been implemented to serve those with print disabilities. (A print disability can be a learning…

  10. Digital Roundup

    ERIC Educational Resources Information Center

    Horn, Michael B.

    2013-01-01

    State policy is crucial to the spread of digital-learning opportunities at the elementary and secondary level. A review of recent legislative action reveals policies that are constantly in flux and differ quite markedly from one state to another. Some have hoped for model digital-learning legislation that could handle all the various issues…

  11. Why Digitize?

    ERIC Educational Resources Information Center

    Smith, Abby

    This paper is a response to discussions of digitization at meetings of the National Humanities Alliance (NHA). NHA asked the Council on Library and Information Resources (CLIR) to evaluate the experiences of cultural institutions with digitization projects to date and to summarize what has been learned about the advantages and disadvantages of…

  12. Closing the Gender Gap: The Case for Gender-Specific Alcoholism Research

    PubMed Central

    Ruiz, Susan Mosher; Oscar-Berman, Marlene

    2016-01-01

    As the number of women who use alcohol increases, so does the number of women who engage in alcohol abuse and develop alcohol dependence. The recent increased focus on women and gender differences in alcoholism research has largely come about following recognition that the face of alcoholism is changing, with alcoholism rates among men remaining stable and rising among women, particularly in younger women. As such, the need to understand gender differences in both acute and long-term effects of alcohol abuse has never been more critical. Gender differences in the long-term effects of chronic alcoholism on the brain and other systems are currently under debate, often with a focus on proclaiming whether men or women suffer the most impact. However, the story appears to be more complex than that. The issue of how alcoholism interacts with gender is complicated, as gender differences in many factors including alcohol metabolism, alcoholism progression, problematic drinking patterns, neurobiology, hormones, and psychiatric comorbidities will contribute to the differences in structural and functional outcomes observed experimentally across domains of inquiry. While women are now much more commonly included in studies of alcohol’s effects on the brain, there remains a need for more explicit examinations of gender effects.

  13. Neural correlates of automatic beliefs about gender and race.

    PubMed

    Knutson, Kristine M; Mah, Linda; Manly, Charlotte F; Grafman, Jordan

    2007-10-01

    Functional MRI was used to identify the brain areas underlying automatic beliefs about gender and race, and suppression of those attitudes. Participants (n = 20; 7 females) were scanned at 3 tesla while performing the Implicit Association Test (IAT), an indirect measure of race and gender bias. We hypothesized that ventromedial prefrontal cortex areas (PFC) would mediate gender and racial stereotypic attitudes, and suppression of these beliefs would recruit dorsolateral prefrontal cortex (DLPFC) and the anterior cingulate cortex (ACC). Performance data on the IAT revealed gender and racial biases. Racial bias was correlated with an explicit measure of racism. Results showed activation of anteromedial PFC and rostral ACC while participants implicitly made associations consistent with gender and racial biases. In contrast, associations incongruent with stereotypes recruited DLPFC. Implicit gender bias was correlated with amygdala activation during stereotypic conditions. Results suggest there are dissociable roles for anteromedial and dorsolateral PFC circuits in the activation and inhibition of stereotypic attitudes. PMID:17133388

  14. Gender Identity and Gender Confusion in Children

    MedlinePlus

    ... games that are more active and enjoy toy soldiers, blocks, and toy trucks. What parents can do: All children need the opportunity to explore different gender roles and different styles of play. Ensure your young child's environment reflects diversity in gender roles and encourages ...

  15. Workshop I: Gender Studies

    NASA Astrophysics Data System (ADS)

    Hennessey, Eden; Kurup, Anitha; Meza-Montes, Lilia; Shastri, Prajval; Ghose, Shohini

    2015-12-01

    Participants in the Gender Studies workshop of the 5th IUPAP International Conference on Women in Physics discussed the gender question in science practice from a policy perspective, informed by investigations from the social science disciplines. The workshop's three sessions—"Equity and Education: Examining Gender Stigma in Science," "A Comparative Study of Women Scientists and Engineers: Experiences in India and the US," and "Toward Gender Equity Through Policy: Characterizing the Social Impact of Interventions—are summarized, and the resulting recommendations presented.

  16. Digital Media and "Girling" at an Elite Girls' School

    ERIC Educational Resources Information Center

    Charles, Claire

    2007-01-01

    In this article, I draw on Judith Butler's notion of performativity to investigate the role of digital technologies in processes of gendered subjectification (or "girling") in elite girls' education. Elite girls' schooling is a site where the potential of digital technologies in mediating student-led constructions and explorations of "femininity"…

  17. Gender and Adolescent Development

    ERIC Educational Resources Information Center

    Perry, David G.; Pauletti, Rachel E.

    2011-01-01

    This article summarizes and critiques recent trends in research and theory on the role of gender in adolescent development. First, gender differences in key areas of adolescent functioning are reviewed. Second, research on 3 constructs that are especially relevant to the investigation of within-gender individual differences in gender…

  18. Gender Differences in Communication.

    ERIC Educational Resources Information Center

    Diedrick, Patricia

    Gender differences in spoken and unspoken emotional expression exist and may be related to gender differences in other realms, particularly in self-esteem. This literature review investigated gender differences in communication, particularly as related to emotional expressiveness, detection of emotional responses, and self-disclosures, in relation…

  19. Gender Effects in Parenting.

    ERIC Educational Resources Information Center

    Copeland, Anne P.; Grossman, Frances K.

    The literature on how parent gender influences responses to children has grown enormously in the past decade; mothers and fathers have been found to differ on many dimensions and to be similar on just as many. Conflicting evidence also exists on how a child's gender affects parenting style. This paper reports some important gender differences in…

  20. Gender and Higher Education

    ERIC Educational Resources Information Center

    Bank, Barbara J., Ed.

    2011-01-01

    This comprehensive, encyclopedic review explores gender and its impact on American higher education across historical and cultural contexts. Challenging recent claims that gender inequities in U.S. higher education no longer exist, the contributors--leading experts in the field--reveal the many ways in which gender is embedded in the educational…

  1. The Morpheme Gender Effect

    ERIC Educational Resources Information Center

    Meunier, Fanny; Seigneuric, Alix; Spinelli, Elsa

    2008-01-01

    In three experiments we explored the mental representation of morphologically complex words in French. Subjects were asked to perform a gender decision task on morphologically complex words that were of the same gender as their base or not. We found that gender decisions were made more slowly for morphologically complex words made from a base with…

  2. The Embryology of Gender

    ERIC Educational Resources Information Center

    Jorge, Juan Carlos

    2010-01-01

    More than 50 years after the appearance of the term "gender" in the clinical setting, we have yet to uncover the mechanisms and factors that lead to gender identity formation. Based on human embryology principles, the scientific reasoning with regard to the sexual differentiation of the body is erroneously applied to gender identity formation. The…

  3. Schools Achieving Gender Equity.

    ERIC Educational Resources Information Center

    Revis, Emma

    This guide is designed to assist teachers presenting the Schools Achieving Gender Equity (SAGE) curriculum for vocational education students, which was developed to align gender equity concepts with the Kentucky Education Reform Act (KERA). Included in the guide are lesson plans for classes on the following topics: legal issues of gender equity,…

  4. Gender and Science.

    PubMed

    2016-05-10

    We are delighted to expand our Cell Metabolism "Rosie project" to highlight an upcoming LabLinks meeting, "The Gender of Science and the Science of Gender" on May 19th in Cambridge, MA. We present the viewpoints of the speakers and other leaders on the ever-fascinating topic of gender in science. PMID:27166933

  5. Beyond Gender Identity?

    ERIC Educational Resources Information Center

    Rasmussen, Mary Lou

    2009-01-01

    This paper focuses on the continuing significance of gender identity as a category of analysis within the field of gender theory and research in education. I begin by considering contemporary discussions of the limitations of research relating to gender theory and research in education. Following on from this, I explore some contemporary…

  6. Genders and sexualities in individuation: theoretical and clinical explorations.

    PubMed

    McKenzie, Susan

    2010-02-01

    Gender assignment, as a key aspect of identity and cultural position, has existed throughout recorded time and across all cultures. An individual's biological sex and particular cultural milieu has a profound effect on their sense of themselves as a gendered being. Sexuality is a more recent marker in identity formation. In the last few decades there has emerged a great deal of interest in the psychology of gender formation, in the interplay of biological sex, culture, brain development, and attachment experiences in the formation of gender identities. Queer theory in its post-modern deconstructionist thinking has suggested that gender is a socially 'constructed' concept having no biological or psychological precursors or realities. Contemporary developmental psychoanalysis is bridging the gap between concepts of gender as purely biological and gender as non-existent. In this paper I explore the emergence of same-sex desire at mid-life, presenting two case histories with extensive dream material. The impact of sexual desire on gender identities is examined through the lenses of culture, dynamic systems theory, neuroscience, and depth psychology. The use of dream analysis as a window into the body/mind movement of gender emergence reflects my sense of gender as a fluidly shifting reality of mind, neither hardwired nor fictional. PMID:20433498

  7. The Uncanny, Digital Texts and Literacy

    ERIC Educational Resources Information Center

    Carrington, Victoria

    2005-01-01

    Literacy is one of the binding threads of modern society. Print text and literacy are irretrievably intertwined with many of the core themes of industrial society: family, gender, nation state. In the shift to new digital technologies, changing sociocultural landscapes and new theoretical frames, the growing difficulty in defining and delineating…

  8. Digital clubbing

    PubMed Central

    Sarkar, Malay; Mahesh, D. M.; Madabhavi, Irappa

    2012-01-01

    Digital clubbing is an ancient and important clinical signs in medicine. Although clubbed fingers are mostly asymptomatic, it often predicts the presence of some dreaded underlying diseases. Its exact pathogenesis is not known, but platelet-derived growth factor and vascular endothelial growth factor are recently incriminated in its causation. The association of digital clubbing with various disease processes and its clinical implications are discussed in this review. PMID:23243350

  9. Digital Epidemiology

    PubMed Central

    Salathé, Marcel; Bengtsson, Linus; Bodnar, Todd J.; Brewer, Devon D.; Brownstein, John S.; Buckee, Caroline; Campbell, Ellsworth M.; Cattuto, Ciro; Khandelwal, Shashank; Mabry, Patricia L.; Vespignani, Alessandro

    2012-01-01

    Mobile, social, real-time: the ongoing revolution in the way people communicate has given rise to a new kind of epidemiology. Digital data sources, when harnessed appropriately, can provide local and timely information about disease and health dynamics in populations around the world. The rapid, unprecedented increase in the availability of relevant data from various digital sources creates considerable technical and computational challenges. PMID:22844241

  10. Gender determination in populus

    SciTech Connect

    McLetchie, D.N.; Tuskan, G.A.

    1994-12-31

    Gender, the expression of maleness or femaleness, in dioecious plants has been associated with changes in morphology, physiology, ecological position, and commercial importance of several species, including members of the Salicaceae family. Various mechanisms have been proposed to explain the expression of gender in Salicaceae, including sex chromosomes, simple Mendelian genes, quantitative genes, environment, and genotype-by-environment interactions. Published reports would favor a genetic basis for gender. The objective of this study was to identify molecular markers associated with gender in a segregating family of hybrid poplars. Bulked segregant analysis and chi-squared analysis were used to test for the occurrence of sex chromosomes, individual loci, and chromosome ratios (i.e., ploidy levels) as the mechanisms for gender determination. Examination of 2488 PCR based RAPD markers from 1219 primers revealed nine polymorphic bands between male and female bulked samples. However, linkage analysis indicated that none of these markers were significantly associated with gender. Chisquared results for difference in male-to-female ratios between diploid and triploid genotypes also revealed no significant differences. These findings suggest gender is not controlled via sex chromosomes, simple Mendelian loci or ratios of autosome to gender-determining loci. It is possible that gender is determined genetically by regions of the genome not sampled by the tested markers or by a complex of loci operating in an additive threshold manner or in an epistatic manner. It is also possible that gender is determined environmentally at an early zygote stage, canalizing gender expression.

  11. Digital photography

    PubMed Central

    Windsor, J S; Rodway, G W; Middleton, P M; McCarthy, S

    2006-01-01

    Objective The emergence of a new generation of “point‐and‐shoot” digital cameras offers doctors a compact, portable and user‐friendly solution to the recording of highly detailed digital photographs and video images. This work highlights the use of such technology, and provides information for those who wish to record, store and display their own medical images. Methods Over a 3‐month period, a digital camera was carried by a doctor in a busy, adult emergency department and used to record a range of clinical images that were subsequently transferred to a computer database. Results In total, 493 digital images were recorded, of which 428 were photographs and 65 were video clips. These were successfully used for teaching purposes, publications and patient records. Conclusions This study highlights the importance of informed consent, the selection of a suitable package of digital technology and the role of basic photographic technique in developing a successful digital database in a busy clinical environment. PMID:17068281

  12. Digital radiography.

    PubMed

    Mattoon, J S

    2006-01-01

    Digital radiography has been used in human medical imaging since the 1980s with recent and rapid acceptance into the veterinary profession. Using advanced image capture and computer technology, radiographic images are viewed on a computer monitor. This is advantageous because radiographic images can be adjusted using dedicated computer software to maximize diagnostic image quality. Digital images can be accessed at computer workstations throughout the hospital, instantly retrieved from computer archives, and transmitted via the internet for consultation or case referral. Digital radiographic data can also be incorporated into a hospital information system, making record keeping an entirely paperless process. Digital image acquisition is faster when compared to conventional screen-film radiography, improving workflow and patient throughput. Digital radiography greatly reduces the need for 'retake' radiographs because of wide latitude in exposure factors. Also eliminated are costs associated with radiographic film and x-ray film development. Computed radiography, charged coupled devices, and flat panel detectors are types of digital radiography systems currently available. PMID:16971994

  13. Gender Matters in Elementary Education: Research-Based Strategies to Meet the Distinctive Learning Needs of Boys and Girls

    ERIC Educational Resources Information Center

    Bonomo, Virginia

    2010-01-01

    Research indicates that gender influences how children learn. Those findings do not necessarily mean that boys learn one way and girls another. Still, there are significant differences with respect to gender and how our brains develop. Researchers have found that no single area of development influences those gender differences: rather, a…

  14. What Does the Brain Have to Do with Learning?

    ERIC Educational Resources Information Center

    Worden, Jennifer M.; Hinton, Christina; Fischer, Kurt W.

    2011-01-01

    There are several myths about neuroscientific findings that are widespread in education. Some of these myths are left brain/right brain, critical periods for learning, and gender differences in the brain. Belief in these "neuromyths" can negatively affect how we teach children. But ignoring important findings from neuroscience can be just as…

  15. Brain Tumors

    MedlinePlus

    A brain tumor is a growth of abnormal cells in the tissues of the brain. Brain tumors can be benign, with no cancer cells, ... cancer cells that grow quickly. Some are primary brain tumors, which start in the brain. Others are ...

  16. Digital Collections, Digital Libraries & the Digitization of Cultural Heritage Information.

    ERIC Educational Resources Information Center

    Lynch, Clifford

    2002-01-01

    Discusses digital collections and digital libraries. Topics include broadband availability; digital rights protection; content, both non-profit and commercial; digitization of cultural content; sustainability; metadata harvesting protocol; infrastructure; authorship; linking multiple resources; data mining; digitization of reference works;…

  17. Intraoperative virtual brain counseling

    NASA Astrophysics Data System (ADS)

    Jiang, Zhaowei; Grosky, William I.; Zamorano, Lucia J.; Muzik, Otto; Diaz, Fernando

    1997-06-01

    Our objective is to offer online real-tim e intelligent guidance to the neurosurgeon. Different from traditional image-guidance technologies that offer intra-operative visualization of medical images or atlas images, virtual brain counseling goes one step further. It can distinguish related brain structures and provide information about them intra-operatively. Virtual brain counseling is the foundation for surgical planing optimization and on-line surgical reference. It can provide a warning system that alerts the neurosurgeon if the chosen trajectory will pass through eloquent brain areas. In order to fulfill this objective, tracking techniques are involved for intra- operativity. Most importantly, a 3D virtual brian environment, different from traditional 3D digitized atlases, is an object-oriented model of the brain that stores information about different brain structures together with their elated information. An object-oriented hierarchical hyper-voxel space (HHVS) is introduced to integrate anatomical and functional structures. Spatial queries based on position of interest, line segment of interest, and volume of interest are introduced in this paper. The virtual brain environment is integrated with existing surgical pre-planning and intra-operative tracking systems to provide information for planning optimization and on-line surgical guidance. The neurosurgeon is alerted automatically if the planned treatment affects any critical structures. Architectures such as HHVS and algorithms, such as spatial querying, normalizing, and warping are presented in the paper. A prototype has shown that the virtual brain is intuitive in its hierarchical 3D appearance. It also showed that HHVS, as the key structure for virtual brain counseling, efficiently integrates multi-scale brain structures based on their spatial relationships.This is a promising development for optimization of treatment plans and online surgical intelligent guidance.

  18. Brain abscess

    MedlinePlus

    Brain abscesses commonly occur when bacteria or fungi infect part of the brain. As a result, swelling and irritation (inflammation) develop. Infected brain cells, white blood cells, live and dead bacteria, ...

  19. Brain Tumors

    MedlinePlus

    ... brain. Brain tumors can be benign, with no cancer cells, or malignant, with cancer cells that grow quickly. Some are primary brain ... targeted therapy. Targeted therapy uses substances that attack cancer cells without harming normal cells. Many people get ...

  20. Brain components

    MedlinePlus Videos and Cool Tools

    The brain is composed of more than a thousand billion neurons. Specific groups of them, working in concert, provide ... of information. The 3 major components of the brain are the cerebrum, cerebellum, and brain stem. The ...

  1. Brain surgery

    MedlinePlus

    Craniotomy; Surgery - brain; Neurosurgery; Craniectomy; Stereotactic craniotomy; Stereotactic brain biopsy; Endoscopic craniotomy ... cut depends on where the problem in the brain is located. The surgeon creates a hole in ...

  2. Brain Malformations

    MedlinePlus

    Most brain malformations begin long before a baby is born. Something damages the developing nervous system or causes it ... medicines, infections, or radiation during pregnancy interferes with brain development. Parts of the brain may be missing, ...

  3. Beyond Barbie[R] and Mortal Kombat: New Perspectives on Gender and Gaming

    ERIC Educational Resources Information Center

    Kafai, Yasmin B., Ed.; Heeter, Carrie, Ed.; Denner, Jill, Ed.; Sun, Jennifer Y., Ed.

    2008-01-01

    Ten years after the groundbreaking "From Barbie to Mortal Kombat" highlighted the ways gender stereotyping and related social and economic issues permeate digital game play, the number of women and girl gamers has risen considerably. Despite this, gender disparities remain in gaming. Women may be warriors in "World of Warcraft", but they are also…

  4. Does Gender Have a Role in ICT among Finnish Teachers and Students?

    ERIC Educational Resources Information Center

    Ilomaki, Liisa

    2011-01-01

    The digital divide between genders and generations in school, i.e., between teachers and secondary school students in Finland, was investigated comparing statistical data in 1999-2000 and in 2002-2004. ICT skills were intertwined with both generation and gender. Teachers were familiar with some traditional applications, students with new…

  5. From Gender Bias to Gender Awareness in Medical Education

    ERIC Educational Resources Information Center

    Verdonk, Petra; Benschop, Yvonne W. M.; de Haes, Hanneke C. J. M.; Lagro-Janssen, Toine L. M.

    2009-01-01

    Gender is an essential determinant of health and illness. Gender awareness in doctors contributes to equity and equality in health and aims towards better health for men and women. Nevertheless, gender has largely been ignored in medicine. First, it is stated that medicine was "gender blind" by not considering gender whenever relevant. Secondly,…

  6. Patterns of Gender Development

    PubMed Central

    Martin, Carol Lynn; Ruble, Diane N.

    2013-01-01

    A comprehensive theory of gender development must describe and explain long-term developmental patterning and changes and how gender is experienced in the short term. This review considers multiple views on gender patterning, illustrated with contemporary research. First, because developmental research involves understanding normative patterns of change with age, several theoretically important topics illustrate gender development: how children come to recognize gender distinctions and understand stereotypes, and the emergence of prejudice and sexism. Second, developmental researchers study the stability of individual differences over time, which elucidates developmental processes. We review stability in two domains—sex segregation and activities/interests. Finally, a new approach advances understanding of developmental patterns, based on dynamic systems theory. Dynamic systems theory is a metatheoretical framework for studying stability and change, which developed from the study of complex and nonlinear systems in physics and mathematics. Some major features and examples show how dynamic approaches have been and could be applied in studying gender development. PMID:19575615

  7. Gender similarities and differences.

    PubMed

    Hyde, Janet Shibley

    2014-01-01

    Whether men and women are fundamentally different or similar has been debated for more than a century. This review summarizes major theories designed to explain gender differences: evolutionary theories, cognitive social learning theory, sociocultural theory, and expectancy-value theory. The gender similarities hypothesis raises the possibility of theorizing gender similarities. Statistical methods for the analysis of gender differences and similarities are reviewed, including effect sizes, meta-analysis, taxometric analysis, and equivalence testing. Then, relying mainly on evidence from meta-analyses, gender differences are reviewed in cognitive performance (e.g., math performance), personality and social behaviors (e.g., temperament, emotions, aggression, and leadership), and psychological well-being. The evidence on gender differences in variance is summarized. The final sections explore applications of intersectionality and directions for future research. PMID:23808917

  8. Digital caliper

    USGS Publications Warehouse

    Cable, Louella E.

    1967-01-01

    The large number of measurements needed to describe fully the characteristics of biological specimens and other objects has always been tedious and time consuming. The work can be done much more rapidly and with greater accuracy with a digital caliper recently developed by us. The digital caliper is a new electronic instrument built to measure objects precisely throughout the range of 0.1 mm to 1.0 m. Calipers of several different discrete sizes make it possible to select the most convenient unit for the particular range of length and degree of accuracy desired.

  9. Digital Radiography

    NASA Technical Reports Server (NTRS)

    1986-01-01

    System One, a digital radiography system, incorporates a reusable image medium (RIM) which retains an image. No film is needed; the RIM is read with a laser scanner, and the information is used to produce a digital image on an image processor. The image is stored on an optical disc. System allows the radiologist to "dial away" unwanted images to compare views on three screens. It is compatible with existing equipment and cost efficient. It was commercialized by a Stanford researcher from energy selective technology developed under a NASA grant.

  10. Class and Gender

    ERIC Educational Resources Information Center

    Hart, Mechthild

    2005-01-01

    Everyone is dependent on caring labor. Because women's labor is financially beneficial to global capitalism, gender is inseparable from class, regardless of the specific national or cultural contexts.

  11. Gender-Atypical Mental Illness as Male Gender Threat.

    PubMed

    Michniewicz, Kenneth S; Bosson, Jennifer K; Lenes, Joshua G; Chen, Jason I

    2016-07-01

    The present study examined whether men view gender-atypical (i.e., feminine) psychological disorders as threats to their gender status. Men and women (N = 355) rated their expectations of gender status loss, feelings of distress, and help-seeking intentions in response to 10 different stereotypically masculine and feminine psychological disorders. Men as compared to women expected greater gender status loss for, and reported more distress to, gender-atypical versus gender-typical disorders. Expectations of gender status loss partially mediated the link between participant gender and distress at the thought of gender-atypical disorders. These findings suggest that feminine disorders pose more powerful gender status threats for men than masculine disorders do and that men's expectations of gender status loss for feminine disorders drive their negative reactions to these mental illnesses. The discussion emphasizes the importance of considering the gender-typicality of disorders, and the implications of these findings for clinical interventions. PMID:25595020

  12. Gender Differences in Processing Speed: A Review of Recent Research

    ERIC Educational Resources Information Center

    Roivainen, Eka

    2011-01-01

    A review of recent large-scale studies on gender differences in processing speed and on the cognitive factors assumed to affect processing speed was performed. It was found that females have an advantage in processing speed tasks involving digits and alphabets as well as in rapid naming tasks while males are faster on reaction time tests and…

  13. Digital Tidbits

    ERIC Educational Resources Information Center

    Kumaran, Maha; Geary, Joe

    2011-01-01

    Technology has transformed libraries. There are digital libraries, electronic collections, online databases and catalogs, ebooks, downloadable books, and much more. With free technology such as social websites, newspaper collections, downloadable online calendars, clocks and sticky notes, online scheduling, online document sharing, and online…

  14. Digital Batteries

    NASA Astrophysics Data System (ADS)

    Hubler, Alfred

    2009-03-01

    The energy density in conventional capacitors is limited by sparking. We present nano-capacitor arrays, where - like in laser diodes and quantum wells [1] - quantization prevents dielectric breakthrough. We show that the energy density and the power/weight ratio are very high, possibly larger than in hydrogen [2]. Digital batteries are a potential clean energy source for cars, laptops, and mobile devices. The technology is related to flash drives. However, because of the high energy density, safety is a concern. Digital batteries can be easily and safely charged and discharged. In the discharged state they pose no danger. Even if a charged digital battery were to explode, it would produce no radioactive waste, no long-term radiation, and probably could be designed to produce no noxious chemicals. We discuss methodologies to prevent shorts and other measures to make digital batteries safe. [1] H. Higuraskh, A. Toriumi, F. Yamaguchi, K. Kawamura, A. Hubler, Correlation Tunnel Device, U. S. Patent No. 5,679,961 (1997) [2] Alfred Hubler, http://server10.how-why.com/blog/

  15. Digital books.

    PubMed

    Wink, Diane M

    2011-01-01

    In this bimonthly series, the author examines how nurse educators can use the Internet and Web-based computer technologies such as search, communication, and collaborative writing tools; social networking and social bookmarking sites; virtual worlds; and Web-based teaching and learning programs. This article describes digital books. PMID:22024672

  16. Digital Badges

    ERIC Educational Resources Information Center

    Frederiksen, Linda

    2013-01-01

    Unlike so much of the current vocabulary in education and technology that seems to stir more confusion than clarity, most public service librarians may already have a general idea about digital badges. As visual representations of individual accomplishments, competencies or skills that are awarded by groups, institutions, or organizations, they…

  17. The "Digital Natives" Debate: An Investigation of the Digital Propensities of University Students

    ERIC Educational Resources Information Center

    Demirbilek, Muhammet

    2014-01-01

    The purpose of this research is to determine the digital propensities of post-secondary students (N=409) in various faculties/colleges at a large state university located in southwestern Turkey. It was also examined whether gender, the program attended, socioeconomic status, education type (first and second shift education), the number of family…

  18. Your Brain on Art: Emergent Cortical Dynamics During Aesthetic Experiences.

    PubMed

    Kontson, Kimberly L; Megjhani, Murad; Brantley, Justin A; Cruz-Garza, Jesus G; Nakagome, Sho; Robleto, Dario; White, Michelle; Civillico, Eugene; Contreras-Vidal, Jose L

    2015-01-01

    The brain response to conceptual art was studied with mobile electroencephalography (EEG) to examine the neural basis of aesthetic experiences. In contrast to most studies of perceptual phenomena, participants were moving and thinking freely as they viewed the exhibit The Boundary of Life is Quietly Crossed by Dario Robleto at the Menil Collection-Houston. The brain activity of over 400 subjects was recorded using dry-electrode and one reference gel-based EEG systems over a period of 3 months. Here, we report initial findings based on the reference system. EEG segments corresponding to each art piece were grouped into one of three classes (complex, moderate, and baseline) based on analysis of a digital image of each piece. Time, frequency, and wavelet features extracted from EEG were used to classify patterns associated with viewing art, and ranked based on their relevance for classification. The maximum classification accuracy was 55% (chance = 33%) with delta and gamma features the most relevant for classification. Functional analysis revealed a significant increase in connection strength in localized brain networks while subjects viewed the most aesthetically pleasing art compared to viewing a blank wall. The direction of signal flow showed early recruitment of broad posterior areas followed by focal anterior activation. Significant differences in the strength of connections were also observed across age and gender. This work provides evidence that EEG, deployed on freely behaving subjects, can detect selective signal flow in neural networks, identify significant differences between subject groups, and report with greater-than-chance accuracy the complexity of a subject's visual percept of aesthetically pleasing art. Our approach, which allows acquisition of neural activity "in action and context," could lead to understanding of how the brain integrates sensory input and its ongoing internal state to produce the phenomenon which we term aesthetic experience

  19. Your Brain on Art: Emergent Cortical Dynamics During Aesthetic Experiences

    PubMed Central

    Kontson, Kimberly L.; Megjhani, Murad; Brantley, Justin A.; Cruz-Garza, Jesus G.; Nakagome, Sho; Robleto, Dario; White, Michelle; Civillico, Eugene; Contreras-Vidal, Jose L.

    2015-01-01

    The brain response to conceptual art was studied with mobile electroencephalography (EEG) to examine the neural basis of aesthetic experiences. In contrast to most studies of perceptual phenomena, participants were moving and thinking freely as they viewed the exhibit The Boundary of Life is Quietly Crossed by Dario Robleto at the Menil Collection-Houston. The brain activity of over 400 subjects was recorded using dry-electrode and one reference gel-based EEG systems over a period of 3 months. Here, we report initial findings based on the reference system. EEG segments corresponding to each art piece were grouped into one of three classes (complex, moderate, and baseline) based on analysis of a digital image of each piece. Time, frequency, and wavelet features extracted from EEG were used to classify patterns associated with viewing art, and ranked based on their relevance for classification. The maximum classification accuracy was 55% (chance = 33%) with delta and gamma features the most relevant for classification. Functional analysis revealed a significant increase in connection strength in localized brain networks while subjects viewed the most aesthetically pleasing art compared to viewing a blank wall. The direction of signal flow showed early recruitment of broad posterior areas followed by focal anterior activation. Significant differences in the strength of connections were also observed across age and gender. This work provides evidence that EEG, deployed on freely behaving subjects, can detect selective signal flow in neural networks, identify significant differences between subject groups, and report with greater-than-chance accuracy the complexity of a subject's visual percept of aesthetically pleasing art. Our approach, which allows acquisition of neural activity “in action and context,” could lead to understanding of how the brain integrates sensory input and its ongoing internal state to produce the phenomenon which we term aesthetic experience

  20. Gender Differences in Cognitive Abilities: The Mediating Role of Health State and Health Habits

    ERIC Educational Resources Information Center

    Jorm, Anthony F.; Anstey, Kaarin J.; Christensen, Helen; Rodgers, Bryan

    2004-01-01

    Gender differences were examined in performance on the California Verbal Learning Test (immediate and delayed recall), Digit Span Backwards, Symbol-Digit Modalities Test, Spot-the-Word, and simple and choice reaction time. The data came from a community survey involving 2404 people aged 20-24 years, 2530 aged 40-44 years, and 2551 aged 60-64…

  1. Gender, Persuasion Techniques, and Collaboration.

    ERIC Educational Resources Information Center

    Raign, Kathryn Rosser; Sims, Brenda R.

    1993-01-01

    Examines preconceptions of four proposal developers about three factors: effective and ineffective collaboration; gender's effects on collaboration; and gender's effect on persuasion. Finds the discourse techniques used by men and women do not parallel a person's gender. (RS)

  2. Gender, Toys and Learning

    ERIC Educational Resources Information Center

    Francis, Becky

    2010-01-01

    In spite of continuing patterning of curriculum subject preference and choice by gender, there has been little recent attention to the argument developed in the 1970s that children play with different toys according to their gender, and that these provide girls and boys with (different) curriculum-related skills. The article describes a…

  3. Gender and Peer Response

    ERIC Educational Resources Information Center

    Tomlinson, Elizabeth

    2009-01-01

    This case study examines written peer response materials generated by small groups with varying gender compositions. Based on those observations, the author offers several pedagogical implications. She suggests that groups' gender make-up often does influence written feedback provided by group members during peer response sessions. By better…

  4. Gender Inequality at Work.

    ERIC Educational Resources Information Center

    Jacobs, Jerry A., Ed.

    These 14 papers address many dimensions of gender inequality at work. The empirical studies include examinations of original surveys, secondary analyses of large data sets, and historical reports assaying the significance of personal, family, and structural factors with regard to gender in the workplace. An introduction (Jacobs) sketches how sex…

  5. Gender Equity. IDRA Forum.

    ERIC Educational Resources Information Center

    IDRA Newsletter, 1994

    1994-01-01

    This newsletter contains six articles on issues of gender equity for Chicanas and other women. "Recognizing Chicana Contributions: Cultural History & Gender Equity on the Line" (Mikki Symonds) discusses the invisibility of Mexican Americans in general and of Chicanas in particular in U.S. history books, school curricula, and pop culture, and…

  6. Gender-Friendly Schools

    ERIC Educational Resources Information Center

    King, Kelley; Gurian, Michael; Stevens, Kathy

    2010-01-01

    The authors, who have worked with more than 2,000 schools across the United States in efforts to close gender gaps, describe how gender-related issues consistently intersect and interfere with school improvement efforts. They present statistics showing that schools are now failing boys in more areas than girls, and describe how "the structures,…

  7. Gender in Early Childhood.

    ERIC Educational Resources Information Center

    Yelland, Nicola, Ed.

    The construction of gender is a systematic process that begins at birth and is continually shaped, molded, and reshaped throughout life. This book examines practices with young children with respect to the construction of gender and the expectations of society, schools, and families. The book is organized into two parts. The first part considers…

  8. Grammatical Gender in Translation

    ERIC Educational Resources Information Center

    Bordag, Denisa; Pechmann, Thomas

    2008-01-01

    In three experiments native speakers of Czech translated bare nouns and gender-marked adjective + noun phrases into German, their second language (L2). In Experiments 1-3 we explored the so-called gender interference effect from first language (L1) as observed in previous picture naming studies (naming latencies were longer when the L1 noun and…

  9. Gender Roles and Coping.

    ERIC Educational Resources Information Center

    Patterson, Joan M.; McCubbin, Hamilton I.

    1984-01-01

    Examined the relationship of gender-role orientation and specific behavioral coping responses of wives (N=82) experiencing a long-term separation from their military spouses. Results showed that an androgynous gender-role orientation was significantly associated with four of the five coping patterns identified as helpful to wives managing a…

  10. Issues of Gender. Symposium.

    ERIC Educational Resources Information Center

    2002

    This symposium is comprised of three papers on issues of gender in human resource development (HRD). "The Impact of Awareness and Action on the Implementation of a Women's Network" (Laura L. Bierema) reports on research to examine how gender consciousness emerges through the formation of in-company networks to promote corporate women's status. It…

  11. Gender and School Education.

    ERIC Educational Resources Information Center

    Collins, Cherry; Batten, Margaret; Ainley, John; Getty, Corinne

    The Gender and School Education study was undertaken to collect baseline data against which progress in implementing the National Policy for the Education of Girls in Australian Schools can be measured. The study was designed to provide data on gender matters related to boys as well as girls. A total of 408 schools across Australia were involved:…

  12. Are Numbers Gendered?

    ERIC Educational Resources Information Center

    Wilkie, James E. B.; Bodenhausen, Galen V.

    2012-01-01

    We examined the possibility that nonsocial, highly generic concepts are gendered. Specifically, we investigated the gender connotations of Arabic numerals. Across several experiments, we show that the number 1 and other odd numbers are associated with masculinity, whereas the number 2 and other even numbers are associated with femininity, in ways…

  13. Gender dysphoria and children.

    PubMed

    Nicholson, Chance; McGuinness, Teena M

    2014-08-01

    The age at which gender dysphoria can be diagnosed with enough certainty to justify medical intervention is controversial. The aim of this article is to explore current literature as it relates to the gender reassignment process and diagnostic indicators supporting an appropriate age for intervention. The timing of diagnosis and treatment of gender dysphoria remains the center of debate between the long-term effects of early intervention versus delay of treatment. Limited research is available on gender dysphoria treatment protocols for children. However, preliminary studies suggest that early intervention improves the quality of life in individuals who are transgender. Ongoing research suggests that it may be possible to confirm gender dysphoria at an earlier age. PMID:24972388

  14. Is the gap more than gender? A longitudinal analysis of gender, gender role orientation, and earnings.

    PubMed

    Judge, Timothy A; Livingston, Beth A

    2008-09-01

    This study investigated the relationships among gender, gender role orientation (i.e., attitudes toward the gendered separation of roles at work and at home), and earnings. A multilevel model was conceptualized in which gender role orientation and earnings were within-individual variables that fluctuate over time (although predictors of between-individual differences in gender role orientation were also considered). Results indicated that whereas traditional gender role orientation was positively related to earnings, gender significantly predicted the slope of this relationship: Traditional gender role orientation was strongly positively associated with earnings for men; it was slightly negatively associated with earnings for women. Occupational segregation partly explained these gender differences. Overall, the results suggest that although gender role attitudes are becoming less traditional for men and for women, traditional gender role orientation continues to exacerbate the gender wage gap. PMID:18808221

  15. Gender and creativity: an overview of psychological and neuroscientific literature.

    PubMed

    Abraham, Anna

    2016-06-01

    The topic of gender differences in creativity is one that generates substantial scientific and public interest, but also courts considerable controversy. Owing to the heterogeneous nature of the findings associated with this line of research, the general picture often appears puzzling or obscure. This article presents a selective overview of psychological and neuroscientific literature that has a relevant bearing on the theme of gender and creativity. Topics that are explored include the definition and methods of assessing creativity, a summary of behavioral investigations on gender in relation to creativity, postulations that have been put forward to understand gender differences in creative achievement, gender-based differences in the structure and function of the brain, gender-related differences in behavioral performance on tasks of normative cognition, and neuroscientific studies of gender and creativity. The article ends with a detailed discussion of the idea that differences between men and women in creative cognition are best explained with reference to the gender-dependent adopted strategies or cognitive style when faced with generative tasks. PMID:26051636

  16. Digital psychiatry.

    PubMed

    Tang, S; Helmeste, D

    2000-02-01

    The American managed care movement has been viewed as a big experiment and is being watched closely by the rest of the world. In the meanwhile, computer-based information technology (IT) is changing the practice of medicine, much more rapidly than managed care. A New World of digitized knowledge and information has been created. Although literature on IT in psychiatry is largely absent in peer-reviewed psychiatric journals, IT is finding its way into all aspects of medicine, particularly psychiatry. Telepsychiatry programs are becoming very popular. At the same time, medical information sites are flourishing and evolving into a new health-care industry. Patient-physician information asymmetry is decreasing as patients are gaining easy access to medical information hitherto only available to professionals. Thus, psychiatry is facing another paradigm shift, at a time when most attention has been focused on managed care. In this new digital world, knowledge and information are no longer the sole property of professionals. Value will migrate from traditional in-person office-based therapy to digital clinical products, from in-person library search and classroom didactic instruction to interactive on-line searches and distance learning. In this time of value migration, psychiatrists have to determine what their 'distinctive competence' is and where best to add value in the health-care delivery value chain. The authors assess the impact of IT on clinical psychiatry and review how clinical practice, education and research in psychiatry are expected to change in this emerging digital world. PMID:15558872

  17. The influence of biological sex, sexuality and gender role on interpersonal distance.

    PubMed

    Uzzell, David; Horne, Nathalie

    2006-09-01

    This research reports on a conceptually and methodologically innovative study, which sought to measure the influence of gender on interpersonal distance. In so doing, we argue for an important distinction to be made between biological sex, gender role, and sexuality. To date, however, progress in the study of interpersonal distance (IPD) has been inhibited by poor operational definitions and inadequate measurement methodologies. For our own investigation, we innovated on methodology by devising the digital video-recording IPD method (DiVRID) that records interpersonal spatial relationships using high quality digital video equipment. The findings highlighted not only the validity of our innovative method of investigation, but also that a more sophisticated conceptualization of the impact of gender on IPD is warranted than can be accounted for by biological sex differences. In this study, we found that gender role accounts for more of the variation in IPD than the conventionally reported gender variable, sex. PMID:16984722

  18. Here, but not there: Cross-national variability of gender effects in arithmetic.

    PubMed

    Shen, Chen; Vasilyeva, Marina; Laski, Elida V

    2016-06-01

    The current study examined gender differences in arithmetic performance among first graders from the United States, Russia, and Taiwan. Children (N=250, Mage=7 years 2 months) solved simple (single-digit) and complex (mixed- and double-digit) addition problems and explained their strategies. On simple problems, there were gender differences in strategies that varied across countries but no differences in accuracy. On complex problems, there were gender differences among American and Russian students in strategy use that mediated differences in accuracy. In contrast, among Taiwanese students, there were no gender differences in strategies or accuracy. The pattern of results suggests that educational context may play a role in gender differences in mathematics. PMID:26914105

  19. Complementing Gender Analysis Methods.

    PubMed

    Kumar, Anant

    2016-01-01

    The existing gender analysis frameworks start with a premise that men and women are equal and should be treated equally. These frameworks give emphasis on equal distribution of resources between men and women and believe that this will bring equality which is not always true. Despite equal distribution of resources, women tend to suffer and experience discrimination in many areas of their lives such as the power to control resources within social relationships, and the need for emotional security and reproductive rights within interpersonal relationships. These frameworks believe that patriarchy as an institution plays an important role in women's oppression, exploitation, and it is a barrier in their empowerment and rights. Thus, some think that by ensuring equal distribution of resources and empowering women economically, institutions like patriarchy can be challenged. These frameworks are based on proposed equality principle which puts men and women in competing roles. Thus, the real equality will never be achieved. Contrary to the existing gender analysis frameworks, the Complementing Gender Analysis framework proposed by the author provides a new approach toward gender analysis which not only recognizes the role of economic empowerment and equal distribution of resources but suggests to incorporate the concept and role of social capital, equity, and doing gender in gender analysis which is based on perceived equity principle, putting men and women in complementing roles that may lead to equality. In this article the author reviews the mainstream gender theories in development from the viewpoint of the complementary roles of gender. This alternative view is argued based on existing literature and an anecdote of observations made by the author. While criticizing the equality theory, the author offers equity theory in resolving the gender conflict by using the concept of social and psychological capital. PMID:25941756

  20. Gender Attribution and Gender Agreement in French Williams Syndrome

    ERIC Educational Resources Information Center

    Boloh, Yves; Ibernon, Laure; Royer, Stephanie; Escudier, Frederique; Danillon, Aurelia

    2009-01-01

    Previous studies on grammatical gender in French individuals with Williams syndrome (WS) have led to conflicting findings and interpretations regarding keys abilities--gender attribution and gender agreement. New production data from a larger SW sample (N = 24) showed that gender attribution scores in SW participants exactly mirrored those of…

  1. Gender Differences in the Motivational Processing of Facial Beauty

    ERIC Educational Resources Information Center

    Levy, Boaz; Ariely, Dan; Mazar, Nina; Chi, Won; Lukas, Scott; Elman, Igor

    2008-01-01

    Gender may be involved in the motivational processing of facial beauty. This study applied a behavioral probe, known to activate brain motivational regions, to healthy heterosexual subjects. Matched samples of men and women were administered two tasks: (a) key pressing to change the viewing time of average or beautiful female or male facial…

  2. Gender differences in justice evaluations: Evidence from fMRI.

    PubMed

    Dulebohn, James H; Davison, Robert B; Lee, Seungcheol Austin; Conlon, Donald E; McNamara, Gerry; Sarinopoulos, Issidoros C

    2016-02-01

    Justice research examining gender differences has yielded contrasting findings. This study enlists advanced techniques in cognitive neuroscience (fMRI) to examine gender differences in brain activation patterns in response to procedural and distributive justice manipulations. We integrate social role, information processing, justice, and neuroscience literature to posit and test for gender differences in 2 neural subsystems known to be involved in the appraisal of self-relevant events. Results indicate that the relationship between justice information processing and neural activity in areas representing these subsystems is significantly influenced by gender, with greater activation for females than males during consideration of both procedural and distributive justice information. In addition, we find evidence that gender and distributive injustice interact to influence bargaining behavior, with females rejecting ultimatum game offers more frequently than males. Results also demonstrate activation in the ventromedial prefrontal cortex (vmPFC) and ventral striatum brain regions during procedural justice evaluation is associated with offer rejection in females, but not in males. Managerial implications based on the study's support for gender differences in justice perceptions are discussed. PMID:26348480

  3. Gender differences in reward-related decision processing under stress

    PubMed Central

    Sakaki, Michiko; Vasunilashorn, Sarinnapha; Nga, Lin; Somayajula, Sangeetha; Chen, Eric Y.; Samii, Nicole; Mather, Mara

    2012-01-01

    Recent research indicates gender differences in the impact of stress on decision behavior, but little is known about the brain mechanisms involved in these gender-specific stress effects. The current study used functional magnetic resonance imaging (fMRI) to determine whether induced stress resulted in gender-specific patterns of brain activation during a decision task involving monetary reward. Specifically, we manipulated physiological stress levels using a cold pressor task, prior to a risky decision making task. Healthy men (n = 24, 12 stressed) and women (n = 23, 11 stressed) completed the decision task after either cold pressor stress or a control task during the period of cortisol response to the cold pressor. Gender differences in behavior were present in stressed participants but not controls, such that stress led to greater reward collection and faster decision speed in males but less reward collection and slower decision speed in females. A gender-by-stress interaction was observed for the dorsal striatum and anterior insula. With cold stress, activation in these regions was increased in males but decreased in females. The findings of this study indicate that the impact of stress on reward-related decision processing differs depending on gender. PMID:21609968

  4. Brain abscess

    MedlinePlus

    ... with certain heart disorders, may receive antibiotics before dental or other procedures to help reduce the risk of infection. Alternative Names Abscess - brain; Cerebral abscess; CNS abscess Images Amebic brain ...

  5. Brain Diseases

    MedlinePlus

    The brain is the control center of the body. It controls thoughts, memory, speech, and movement. It regulates the function of many organs. When the brain is healthy, it works quickly and automatically. However, ...

  6. Brain surgery

    MedlinePlus

    Craniotomy; Surgery - brain; Neurosurgery; Craniectomy; Stereotactic craniotomy; Stereotactic brain biopsy; Endoscopic craniotomy ... Before surgery, the hair on part of the scalp is shaved and the area is cleaned. The doctor makes ...

  7. Brain Health

    MedlinePlus

    ... exercise, diet and nutrition, cognitive activity, and social engagement — can help keep your body and brain ... Stay Mentally Active > Mentally challenging activities and social engagement may support brain health. Learn More Plan ahead ...

  8. Gendered Language in Interactive Discourse

    ERIC Educational Resources Information Center

    Hussey, Karen A.; Katz, Albert N.; Leith, Scott A.

    2015-01-01

    Over two studies, we examined the nature of gendered language in interactive discourse. In the first study, we analyzed gendered language from a chat corpus to see whether tokens of gendered language proposed in the gender-as-culture hypothesis (Maltz and Borker in "Language and social identity." Cambridge University Press, Cambridge, pp…

  9. Gender Asymmetries in Today's Russia

    ERIC Educational Resources Information Center

    Rimashevskaia, N. M.

    2011-01-01

    There can be no doubt that gender attitudes and the gender stereotypes formed on their basis have a deep-rooted social character. This stems unequivocally from the parallels of development of social processes and gender models. The ideology of gender began to flourish in Russia along with perestroika, an ideology that in the past quarter-century…

  10. The Brain.

    ERIC Educational Resources Information Center

    Hubel, David H.

    1979-01-01

    This article on the brain is part of an entire issue about neurobiology and the question of how the human brain works. The brain as an intricate tissue composed of cells is discussed based on the current knowledge and understanding of its composition and structure. (SA)

  11. Brain Aneurysm

    MedlinePlus

    A brain aneurysm is an abnormal bulge or "ballooning" in the wall of an artery in the brain. They are sometimes called berry aneurysms because they ... often the size of a small berry. Most brain aneurysms produce no symptoms until they become large, ...

  12. Gender differences in schizophrenia.

    PubMed

    Andia, A M; Zisook, S; Heaton, R K; Hesselink, J; Jernigan, T; Kuck, J; Morganville, J; Braff, D L

    1995-08-01

    In an assessment of gender differences in schizophrenia, 85 outpatients (53 men and 32 women) with schizophrenia were evaluated for illness history, symptom severity, IQ, neurocognitive status, cerebral volume loss, and cortical asymmetry. Social functioning was assessed using marital status, independent living skills, and employment status. Significant gender differences were found, as women were on lower doses of neuroleptic medications and more frequently met criteria for paranoid and disorganized subtypes of schizophrenia than men. Women also were better educated and more often married, living independently, and employed. No gender differences were found in present age, symptom severity, neurocognitive functioning, or clinical magnetic resonance imaging scan readings. Our findings suggest that women may experience less of the adverse interpersonal psychosocial consequences of schizophrenia than men, even when symptom and neurocognitive status is equivalent between groups. However, more extensive investigations are warranted to better understand the role of pathophysiological or social mechanisms in gender differences. PMID:7643064

  13. Adolescents with gender dysphoria.

    PubMed

    Cohen-Kettenis, Peggy T; Klink, Daniel

    2015-06-01

    Young people with gender dysphoria are increasingly seen by pediatric endocrinologists. Mental health child specialists assess the adolescent and give advice about psychological or medical treatment. Provided they fulfill eligibility and readiness criteria, adolescents may receive pubertal suspension, consisting of using gonadotrophin-releasing hormone analogs, later followed by cross-sex hormones (sex steroids of the experienced gender). If they fulfill additional criteria, they may have various types of gender affirming surgery. Current issues involve safety aspects. Although generally considered safe in the short-term, the long-term effects regarding bone health and cardiovascular risks are still unknown. Therefore, vigilance is warranted during and long after completion of the last gender affirming surgeries. The timing of the various treatment steps is also under debate: instead of fixed age limits, the cognitive and emotional maturation, along with the physical development, are now often considered as more relevant. PMID:26051304

  14. Asking gender questions

    NASA Astrophysics Data System (ADS)

    Pritchard, Jonathan; Masters, Karen; Allen, James; Contenta, Filippo; Huckvale, Leo; Wilkins, Stephen; Zocchi, Alice

    2014-12-01

    Jonathan Pritchard, Karen Masters, James Allen, Filippo Contenta, Leo Huckvale, Stephen Wilkins and Alice Zocchi report on a survey of the gender of astronomers attending and asking questions at this year's UK National Astronomy Meeting.

  15. Malingering in Toxic Exposure. Classification Accuracy of Reliable Digit Span and WAIS-III Digit Span Scaled Scores

    ERIC Educational Resources Information Center

    Greve, Kevin W.; Springer, Steven; Bianchini, Kevin J.; Black, F. William; Heinly, Matthew T.; Love, Jeffrey M.; Swift, Douglas A.; Ciota, Megan A.

    2007-01-01

    This study examined the sensitivity and false-positive error rate of reliable digit span (RDS) and the WAIS-III Digit Span (DS) scaled score in persons alleging toxic exposure and determined whether error rates differed from published rates in traumatic brain injury (TBI) and chronic pain (CP). Data were obtained from the files of 123 persons…

  16. Left Brain. Right Brain. Whole Brain

    ERIC Educational Resources Information Center

    Farmer, Lesley S. J.

    2004-01-01

    As the United States student population is becoming more diverse, library media specialists need to find ways to address these distinctive needs. However, some of these differences transcend culture, touching on variations in the brain itself. Most people have a dominant side of the brain, which can affect their personality and learning style.…

  17. Gender dysphoria in childhood.

    PubMed

    Ristori, Jiska; Steensma, Thomas D

    2016-01-01

    Gender dysphoria (GD) in childhood is a complex phenomenon characterized by clinically significant distress due to the incongruence between assigned gender at birth and experienced gender. The clinical presentation of children who present with gender identity issues can be highly variable; the psychosexual development and future psychosexual outcome can be unclear, and consensus about the best clinical practice is currently under debate. In this paper a clinical picture is provided of children who are referred to gender identity clinics. The clinical criteria are described including what is known about the prevalence of childhood GD. In addition, an overview is presented of the literature on the psychological functioning of children with GD, the current knowledge on the psychosexual development and factors associated with the persistence of GD, and explanatory models for psychopathology in children with GD together with other co-existing problems that are characteristic for children referred for their gender. In light of this, currently used treatment and counselling approaches are summarized and discussed, including the integration of the literature detailed above. PMID:26754056

  18. Brain Basics: Know Your Brain

    MedlinePlus

    ... fact sheet is a basic introduction to the human brain. It may help you understand how the healthy ... largest and most highly developed part of the human brain: it consists primarily of the cerebrum ( 2 ) and ...

  19. Scanning for Digitization Projects

    ERIC Educational Resources Information Center

    Wentzel, Larry

    2007-01-01

    Librarians and archivists find themselves facing the prospect of digitization. Everyone is doing it, everyone needs it. Discussions rage nationally and internationally concerning what to digitize and the best means to present and retain digital objects. Digitization is the act of making something digital, expressing a physical object "in numerical…

  20. Is the Gap More than Gender? A Longitudinal Analysis of Gender, Gender Role Orientation, and Earnings

    ERIC Educational Resources Information Center

    Judge, Timothy A.; Livingston, Beth A.

    2008-01-01

    This study investigated the relationships among gender, gender role orientation (i.e., attitudes toward the gendered separation of roles at work and at home), and earnings. A multilevel model was conceptualized in which gender role orientation and earnings were within-individual variables that fluctuate over time (although predictors of…

  1. Brain Signature Characterizing the Body-Brain-Mind Axis of Transsexuals

    PubMed Central

    Chao, Hsiang-Tai; Tu, Pei-Chi; Li, Cheng-Ta; Cheng, Chou-Ming; Su, Tung-Ping; Lee, Ying-Chiao; Hsieh, Jen-Chuen

    2013-01-01

    Individuals with gender identity disorder (GID), who are commonly referred to as transsexuals (TXs), are afflicted by negative psychosocial stressors. Central to the psychological complex of TXs is the conviction of belonging to the opposite sex. Neuroanatomical and functional brain imaging studies have demonstrated that the GID is associated with brain alterations. In this study, we found that TXs identify, when viewing male-female couples in erotic or non-erotic (“neutral”) interactions, with the couple member of the desired gender in both situations. By means of functional magnetic resonance imaging, we found that the TXs, as opposed to controls (CONs), displayed an increased functional connectivity between the ventral tegmental area, which is associated with dimorphic genital representation, and anterior cingulate cortex subregions, which play a key role in social exclusion, conflict monitoring and punishment adjustment. The neural connectivity pattern suggests a brain signature of the psychosocial distress for the gender-sex incongruity of TXs. PMID:23923023

  2. The Brains Behind the Brain.

    ERIC Educational Resources Information Center

    D'Arcangelo, Marcia

    1998-01-01

    Interviews with five neuroscientists--Martin Diamond, Pat Wolfe, Robert Sylwester, Geoffrey Caine, and Eric Jensen--disclose brain-research findings of practical interest to educators. Topics include brain physiology, environmental enrichment, memorization, windows of learning opportunity, brain learning capacity, attention span, student interest,…

  3. Brain anatomical network and intelligence.

    PubMed

    Li, Yonghui; Liu, Yong; Li, Jun; Qin, Wen; Li, Kuncheng; Yu, Chunshui; Jiang, Tianzi

    2009-05-01

    Intuitively, higher intelligence might be assumed to correspond to more efficient information transfer in the brain, but no direct evidence has been reported from the perspective of brain networks. In this study, we performed extensive analyses to test the hypothesis that individual differences in intelligence are associated with brain structural organization, and in particular that higher scores on intelligence tests are related to greater global efficiency of the brain anatomical network. We constructed binary and weighted brain anatomical networks in each of 79 healthy young adults utilizing diffusion tensor tractography and calculated topological properties of the networks using a graph theoretical method. Based on their IQ test scores, all subjects were divided into general and high intelligence groups and significantly higher global efficiencies were found in the networks of the latter group. Moreover, we showed significant correlations between IQ scores and network properties across all subjects while controlling for age and gender. Specifically, higher intelligence scores corresponded to a shorter characteristic path length and a higher global efficiency of the networks, indicating a more efficient parallel information transfer in the brain. The results were consistently observed not only in the binary but also in the weighted networks, which together provide convergent evidence for our hypothesis. Our findings suggest that the efficiency of brain structural organization may be an important biological basis for intelligence. PMID:19492086

  4. Brain Anatomical Network and Intelligence

    PubMed Central

    Li, Jun; Qin, Wen; Li, Kuncheng; Yu, Chunshui; Jiang, Tianzi

    2009-01-01

    Intuitively, higher intelligence might be assumed to correspond to more efficient information transfer in the brain, but no direct evidence has been reported from the perspective of brain networks. In this study, we performed extensive analyses to test the hypothesis that individual differences in intelligence are associated with brain structural organization, and in particular that higher scores on intelligence tests are related to greater global efficiency of the brain anatomical network. We constructed binary and weighted brain anatomical networks in each of 79 healthy young adults utilizing diffusion tensor tractography and calculated topological properties of the networks using a graph theoretical method. Based on their IQ test scores, all subjects were divided into general and high intelligence groups and significantly higher global efficiencies were found in the networks of the latter group. Moreover, we showed significant correlations between IQ scores and network properties across all subjects while controlling for age and gender. Specifically, higher intelligence scores corresponded to a shorter characteristic path length and a higher global efficiency of the networks, indicating a more efficient parallel information transfer in the brain. The results were consistently observed not only in the binary but also in the weighted networks, which together provide convergent evidence for our hypothesis. Our findings suggest that the efficiency of brain structural organization may be an important biological basis for intelligence. PMID:19492086

  5. Gender Identity Disorder and Schizophrenia: Neurodevelopmental Disorders with Common Causal Mechanisms?

    PubMed Central

    Rajkumar, Ravi Philip

    2014-01-01

    Gender identity disorder (GID), recently renamed gender dysphoria (GD), is a rare condition characterized by an incongruity between gender identity and biological sex. Clinical evidence suggests that schizophrenia occurs in patients with GID at rates higher than in the general population and that patients with GID may have schizophrenia-like personality traits. Conversely, patients with schizophrenia may experience alterations in gender identity and gender role perception. Neurobiological research, including brain imaging and studies of finger length ratio and handedness, suggests that both these disorders are associated with altered cerebral sexual dimorphism and changes in cerebral lateralization. Various mechanisms, such as Toxoplasma infection, reduced levels of brain-derived neurotrophic factor (BDNF), early childhood adversity, and links with autism spectrum disorders, may account for some of this overlap. The implications of this association for further research are discussed. PMID:25548672

  6. Is the noun ending a cue to grammatical gender processing? An ERP study on sentences in Italian.

    PubMed

    Caffarra, Sendy; Siyanova-Chanturia, Anna; Pesciarelli, Francesca; Vespignani, Francesco; Cacciari, Cristina

    2015-08-01

    Gender-to-ending consistency has been shown to influence grammatical gender retrieval in isolated word presentation. Notwithstanding the wealth of evidence, the exact role and the time course of processing of this distributional information remain unclear. This ERP study investigated if and when the brain detects gender-to-ending consistency in sentences containing Italian determiner-noun pairs. Determiners either agreed or disagreed in gender with the nouns whose endings were reliable or misleading cues to gender (transparent and irregular nouns). Transparent nouns elicited an increased frontal negativity and a late posterior positivity compared to irregular nouns (350-950 ms), suggesting that the system is sensitive to gender-to-ending consistency from relatively early stages of processing. Gender agreement violations evoked a similar LAN-P600 pattern for both types of nouns. The present findings provide evidence for an early detection of reliable gender-related endings during sentence reading. PMID:25817315

  7. Digital demodulator

    NASA Technical Reports Server (NTRS)

    Shull, T. A. (Inventor)

    1982-01-01

    A digital demodulator for converting pulse code modulated data from phase shift key (PSK) to non return to zero (NRZ) and to biphase data is described. The demodulator is composed of standard integrated logic circuits. The key to the demodulation function is a pair of cross coupled one shot multivibrators and which with a flip-flop produce the NRZ-L is all that is required, the circuitry is greatly simplified and the 2(v) times bit rate contraint can be removed from the carrier. A flip-flop, an OR gate, and AND gate and a binary counter generate the bit rate clock (BTCK) for the NRZ-L. The remainder of the circuitry is for converting the NRZ-L and BTCK into biphase data. The device was designed for use in the space shuttle bay environment measurements.

  8. Digital Avionics

    NASA Technical Reports Server (NTRS)

    Koelbl, Terry G.; Ponchak, Denise; Lamarche, Teresa

    2002-01-01

    The field of digital avionics experienced another year of important advances in civil aviation, military systems, and space applications. As a result of the events of 9/11/2001, NASA has pursued activities to apply its aerospace technologies toward improved aviation security. Both NASA Glenn Research Center and Langley Research Center have performed flight research demonstrations using advanced datalink concepts to transmit live pictures from inside a jetliner, and to downlink the contents of the plane's 'black box' recorder in real time. The U.S. Navy and General Electric demonstrated survivable engine control (SEC) algorithms during engine ground tests at the Weapons Survivability Laboratory at China Lake. The scientists at Boeing Satellite Systems advanced the field of stellar inertial technology with the development of a new method for positioning optical star trackers on satellites.

  9. Digital Avionics

    NASA Technical Reports Server (NTRS)

    Koelbl, Terry G.; Ponchak, Denise; Lamarche, Teresa

    2003-01-01

    Digital Avionics activities played an important role in the advancements made in civil aviation, military systems, and space applications. This document profiles advances made in each of these areas by the aerospace industry, NASA centers, and the U.S. military. Emerging communication technologies covered in this document include Internet connectivity onboard aircraft, wireless broadband communication for aircraft, and a mobile router for aircraft to communicate in multiple communication networks over the course of a flight. Military technologies covered in this document include avionics for unmanned combat air vehicles and microsatellites, and head-up displays. Other technologies covered in this document include an electronic flight bag for the Boeing 777, and surveillance systems for managing airport operations.

  10. Digital structural

    USGS Publications Warehouse

    Dohm, J.M.; Anderson, R.C.; Tanaka, K.L.

    1998-01-01

    Magmatic and tectonic activity have both contributed significantly to the surface geology of Mars. Digital structural mapping techniques have now been used to classify and date centers of tectonic activity in the western equatorial region. For example, our results show a center of tectonic activity at Valles Marineris, which may be associated with uplift caused by intrusion. Such evidence may help explain, in part, the development of the large troughs and associated outflow channels and chaotic terrain. We also find a local centre of tectonic activity near the source region of Warrego Valles. Here, we suggest that the valley system may have resulted largely from intrusive-related hydrothermal activity. We hope that this work, together with the current Mars Global Surveyor mission, will lead to a better understanding of the geological processes that shaped the Martian surface.

  11. Digital communication systems

    NASA Astrophysics Data System (ADS)

    Peebles, Peyton Z., Jr.

    The fundamental principles of digital communication and the design of practical digital communication systems are explored in an introductory textbook for senior and graduate students of electrical engineering. Chapters are devoted to sampling principles, baseband digital waveforms, baseband digital systems, bandpass binary digital systems, and M-ary digital systems. Deterministic signals, networks, and random-signal theory are reviewed in extensive appendices, and graphs, flow charts, diagrams, and problems are provided.

  12. Gender equity & human development.

    PubMed

    Vepa, Swarna S

    2007-10-01

    The welfare of both women and men constitutes the human welfare. At the turn of the century amidst the glory of unprecedented growth in national income, India is experiencing the spread of rural distress. It is mainly due to the collapse of agricultural economy. Structural adjustments and competition from large-scale enterprises result in loss of rural livelihoods. Poor delivery of public services and safety nets, deepen the distress. The adverse impact is more on women than on men. This review examines the adverse impact of the events in terms of endowments, livelihood opportunities and nutritional outcomes on women in detail with the help of chosen indicators at two time-periods roughly representing mid nineties and early 2000. The gender equality index computed and the major indicators of welfare show that the gender gap is increasing in many aspects. All the aspects of livelihoods, such as literacy, unemployment and wages now have larger gender gaps than before. Survival indicators such as juvenile sex ratio, infant mortality, child labour have deteriorated for women, compared to men, though there has been a narrowing of gender gaps in life expectancy and literacy. The overall gender gap has widened due to larger gaps in some indicators, which are not compensated by the smaller narrowing in other indicators both in the rural and urban context. PMID:18032808

  13. Brain tumors.

    PubMed Central

    Black, K. L.; Mazziotta, J. C.; Becker, D. P.

    1991-01-01

    Recent advances in experimental tumor biology are being applied to critical clinical problems of primary brain tumors. The expression of peripheral benzodiazepine receptors, which are sparse in normal brain, is increased as much as 20-fold in brain tumors. Experimental studies show promise in using labeled ligands to these receptors to identify the outer margins of malignant brain tumors. Whereas positron emission tomography has improved the dynamic understanding of tumors, the labeled selective tumor receptors with positron emitters will enhance the ability to specifically diagnose and greatly aid in the pretreatment planning for tumors. Modulation of these receptors will also affect tumor growth and metabolism. Novel methods to deliver antitumor agents to the brain and new approaches using biologic response modifiers also hold promise to further improve the management of brain tumors. Images PMID:1848735

  14. Can We Teach Digital Natives Digital Literacy?

    ERIC Educational Resources Information Center

    Ng, Wan

    2012-01-01

    In recent years, there has been much debate about the concept of digital natives, in particular the differences between the digital natives' knowledge and adoption of digital technologies in informal versus formal educational contexts. This paper investigates the knowledge about educational technologies of a group of undergraduate students…

  15. Gender differences in mental health.

    PubMed

    Afifi, M

    2007-05-01

    Effective strategies for mental disorders prevention and its risk factors' reduction cannot be gender neutral, while the risks themselves are gender specific. This paper aims to discuss why gender matters in mental health, to explain the relationship of gender and health-seeking behaviour as a powerful determinant of gender differences, to examine the gender differences in common mental health disorders, namely, depressive and anxiety disorders, eating disorders, schizophrenia, and domestic violence, and finally, to raise some recommendations stemming from this review. PMID:17453094

  16. Gender Dysphoria in Adults.

    PubMed

    Zucker, Kenneth J; Lawrence, Anne A; Kreukels, Baudewijntje P C

    2016-03-28

    Gender dysphoria (GD), a term that denotes persistent discomfort with one's biologic sex or assigned gender, replaced the diagnosis of gender identity disorder in the Diagnostic and Statistical Manual of Mental Disorders in 2013. Subtypes of GD in adults, defined by sexual orientation and age of onset, have been described; these display different developmental trajectories and prognoses. Prevalence studies conclude that fewer than 1 in 10,000 adult natal males and 1 in 30,000 adult natal females experience GD, but such estimates vary widely. GD in adults is associated with an elevated prevalence of comorbid psychopathology, especially mood disorders, anxiety disorders, and suicidality. Causal mechanisms in GD are incompletely understood, but genetic, neurodevelopmental, and psychosocial factors probably all contribute. Treatment of GD in adults, although largely standardized, is likely to evolve in response to the increasing diversity of persons seeking treatment, demands for greater client autonomy, and improved understanding of the benefits and limitations of current treatment modalities. PMID:26788901

  17. Gender differences in trusting strangers: Role of the target's gender.

    PubMed

    Zhao, Na; Zhang, Jianxin

    2016-06-01

    Previous findings on gender differences in the behaviors of individuals, including trusting behaviors, are inconsistent. A criticism is that these studies neglect contextual factors. The present study aims to examine how the target's gender, as a primary context factor, influences the trusting behavior of individuals in one survey and two experimental situations. Results indicate that people tend to trust strangers of the opposite gender more than those of the same gender in mixed-gender situations. Furthermore, females trust females much more than males trust males. The results help people understand that when talking about gender differences in interpersonal situations, the gender identity of target persons should be considered. These findings are somewhat in conflict with those of previous studies conducted in Western cultures, and suggest that culture should also be explored in future studies on gender differences in interpersonal relationships. PMID:26774437

  18. Two sides of gender: ERP evidence for the presence of two routes during gender agreement processing.

    PubMed

    Caffarra, Sendy; Janssen, Niels; Barber, Horacio A

    2014-10-01

    The present ERP study aimed at providing evidence for the existence of two routes in the brain for the processing of morphosyntactic features during language comprehension; a lexical route which retrieves grammatical properties stored in the lexicon without reliance on formal cues, and a form-based route that takes advantage of sub-lexical units strongly related to a specific grammatical class. In the experiment, we investigated grammatical gender agreement processing in Spanish article-noun word pairs using a grammaticality judgment task. Article-noun pairs either agreed or did not agree in gender. Noun transparency was manipulated such that the ending could be strongly associated with a specific gender class (i.e., transparent nouns) or not (i.e., opaque nouns). A visual half-field method was employed and ERPs were recorded in response to the target nouns in order to disentangle the initial hemisphere-specific computations of gender processing. ERP results showed that, while both hemispheres compute agreement dependencies, the left hemisphere is sensitive to the presence of formal gender cues at an early stage (i.e., 350-500 ms) indicating the presence of a form-based route. The right hemisphere showed an ERP effect of transparency, but later than the left hemisphere (i.e., 500-750 ms). These findings confirm the presence of two routes to gender, which can be differently used depending on the availability of transparent endings. In addition, the results showed hemispheric differences in the time course of the form-based route. PMID:25173710

  19. [Diagnosing gender identity].

    PubMed

    Kaltiala-Heino, Riittakerttu; Mattila, Aino; Kärnä, Teemu; Joutsenneimi, Kaisla

    2015-01-01

    Transsexualism and other variations of gender identity are based on a stable sense of identity. The aetiology of this phenomenon is not fully known. Suffering caused by gender dysphoria is alleviated with sex reassignment. The psychiatric assessment of both adolescents and adults has been centralized in Finland to two university hospitals, the Helsinki University Hospital and Tampere University Hospital. In both hospitals, multidisciplinary teams aim at differential diagnosis by using well-known psychiatric and psychological instruments. Wishes for sex reassignment that are caused by a mental health disorder are excluded. Assessment in adolescence is challenging because the identity in youth is still forming. PMID:26237926

  20. Gendered Language in Interactive Discourse.

    PubMed

    Hussey, Karen A; Katz, Albert N; Leith, Scott A

    2015-08-01

    Over two studies, we examined the nature of gendered language in interactive discourse. In the first study, we analyzed gendered language from a chat corpus to see whether tokens of gendered language proposed in the gender-as-culture hypothesis (Maltz and Borker in Language and social identity. Cambridge University Press, Cambridge, pp 196-216, 1982) can be found in interactive language. Of the eight tokens examined only three were found to differ in the hypothesized direction, and these only in male-male dyads. In the second study, we trained a male and a female confederate to use either male or female gendered tokens found to be reliable in Study One in their chats with participants. Our design permits disentangling of effects due to knowledge of the gender of the interlocutors and use of specific language tokens. We find that use of language tokens by the confederate promoted use of the same token by their interlocutor, regardless of knowledge of the confederate's gender. Moreover use of tokens consistent or inconsistent with visible gender influenced how the interlocutor perceived the confederate. Taken together these data are inconsistent with either the notion that gendered language is context independent (as suggested in the gender-as-culture hypothesis) or the notion that gendered language only emerges when gender is made salient, as would, in these studies, occur in mixed-gendered groups. PMID:24664126

  1. Gender Digital Divide and Challenges in Undergraduate Computer Science Programs

    ERIC Educational Resources Information Center

    Stoilescu, Dorian; McDougall, Douglas

    2011-01-01

    Previous research revealed a reduced number of female students registered in computer science studies. In addition, the female students feel isolated, have reduced confidence, and underperform. This article explores differences between female and male students in undergraduate computer science programs in a mid-size university in Ontario. Based on…

  2. Digital photorefraction

    NASA Astrophysics Data System (ADS)

    Costa, Manuel F.; Jorge, Jorge M.

    1997-12-01

    The early evaluation of the visual status of human infants is of a critical importance. It is of utmost importance to the development of the child's visual system that she perceives clear, focused, retinal images. Furthermore if the refractive problems are not corrected in due time amblyopia may occur. Photorefraction is a non-invasive clinical tool rather convenient for application to this kind of population. A qualitative or semi-quantitative information about refractive errors, accommodation, strabismus, amblyogenic factors and some pathologies (cataracts) can the easily obtained. The photorefraction experimental setup we established using new technological breakthroughs on the fields of imaging devices, image processing and fiber optics, allows the implementation of both the isotropic and eccentric photorefraction approaches. Essentially both methods consist on delivering a light beam into the eyes. It is refracted by the ocular media, strikes the retina, focusing or not, reflects off and is collected by a camera. The system is formed by one CCD color camera and a light source. A beam splitter in front of the camera's objective allows coaxial illumination and observation. An optomechanical system also allows eccentric illumination. The light source is a flash type one and is synchronized with the camera's image acquisition. The camera's image is digitized displayed in real time. Image processing routines are applied for image's enhancement and feature extraction.

  3. Digital photorefraction

    NASA Astrophysics Data System (ADS)

    Costa, Manuel F. M.; Jorge, Jorge M.

    1998-01-01

    The early evaluation of the visual status of human infants is of a critical importance. It is of utmost importance to the development of the child's visual system that she perceives clear, focused, retinal images. Furthermore if the refractive problems are not corrected in due time amblyopia may occur. Photorefraction is a non-invasive clinical tool rather convenient for application to this kind of population. A qualitative or semi-quantitative information about refractive errors, accommodation, strabismus, amblyogenic factors and some pathologies (cataracts) can the easily obtained. The photorefraction experimental setup we established using new technological breakthroughs on the fields of imaging devices, image processing and fiber optics, allows the implementation of both the isotropic and eccentric photorefraction approaches. Essentially both methods consist on delivering a light beam into the eyes. It is refracted by the ocular media, strikes the retina, focusing or not, reflects off and is collected by a camera. The system is formed by one CCD color camera and a light source. A beam splitter in front of the camera's objective allows coaxial illumination and observation. An optomechanical system also allows eccentric illumination. The light source is a flash type one and is synchronized with the camera's image acquisition. The camera's image is digitized displayed in real time. Image processing routines are applied for image's enhancement and feature extraction.

  4. Gender, Gender Roles Affecting Mate Preferences in Turkish College Students

    ERIC Educational Resources Information Center

    Gazioglu, A. Esra Ismen

    2008-01-01

    The subject of this study is gender and gender roles affecting mate preferences. The sample of the study consists of 300 undergraduates and master students. To identify students' gender roles the Sex Role Evaluation Inventory (Bem, 1974) is used. The Question List (Bacanli 2001; Buss et. al., 1990) is applied to the sample group to determine the…

  5. Gender Equity Expert Panel: Exemplary & Promising Gender Equity Programs, 2000.

    ERIC Educational Resources Information Center

    Department of Education, Washington, DC.

    The U.S. Department of Education developed the Gender Equity Expert Panel to identify promising and exemplary programs that promote gender equity in and through education. This panel of experts reviewed self-nominated programs to determine whether they met four criteria: evidence of success/effectiveness in promoting gender equity; quality of the…

  6. Evaluating Gender Discrimination Claims: Is There a Gender Similarity Bias?

    ERIC Educational Resources Information Center

    Elkins, Teri J.; Phillips, James S.; Konopaske, Robert; Townsend, Joellyn

    2001-01-01

    Investigated the possible existence of a gender similarity bias in evaluations of gender discrimination allegations, using a laboratory experiment in which the strength of evidence against a defendant company and the gender of the plaintiff were manipulated. Participants were ethnically diverse undergraduate students. Although female mock jurors…

  7. Peculiarities of the Digital Divide in Sub-Saharan Africa

    ERIC Educational Resources Information Center

    Mutula, Stephen M.

    2005-01-01

    Purpose: Seeks to argue that the peculiarities of sub-Saharan Africa, in terms of its socio-cultural diversity, low economic development, linguistic factors, HIV/AIDS pandemic, gender discrimination, low ICT awareness and so on, demand a new model of addressing the digital divide. Design/methodology/approach: Paper largely based on literature…

  8. Dismantling the Digital Divide: A Multicultural Education Framework.

    ERIC Educational Resources Information Center

    Gorski, Paul C.

    2002-01-01

    Describes inequities in access to computers by gender and race, drawing connections between the two and discussing the use of a multicultural education approach to understanding and eliminating the digital divide. This involves such actions as critiquing technology-related inequities in the context of larger educational and social inequities,…

  9. Gender cognition in transgender children.

    PubMed

    Olson, Kristina R; Key, Aidan C; Eaton, Nicholas R

    2015-04-01

    A visible and growing cohort of transgender children in North America live according to their expressed gender rather than their natal sex, yet scientific research has largely ignored this population. In the current study, we adopted methodological advances from social-cognition research to investigate whether 5- to 12-year-old prepubescent transgender children (N = 32), who were presenting themselves according to their gender identity in everyday life, showed patterns of gender cognition more consistent with their expressed gender or their natal sex, or instead appeared to be confused about their gender identity. Using implicit and explicit measures, we found that transgender children showed a clear pattern: They viewed themselves in terms of their expressed gender and showed preferences for their expressed gender, with response patterns mirroring those of two cisgender (nontransgender) control groups. These results provide evidence that, early in development, transgender youth are statistically indistinguishable from cisgender children of the same gender identity. PMID:25749700

  10. Brain Diseases

    MedlinePlus

    ... know what causes some brain diseases, such as Alzheimer's disease. The symptoms of brain diseases vary widely depending on the specific problem. In some cases, damage is permanent. In other cases, treatments such as surgery, medicines, or physical therapy can correct the source of the problem or ...

  11. H. Sapiens Digital: From Digital Immigrants and Digital Natives to Digital Wisdom

    ERIC Educational Resources Information Center

    Prensky, Marc

    2009-01-01

    As we move further into the 21st century, the digital native/digital immigrant paradigm created by Marc Prensky in 2001 is becoming less relevant. In this article, Prensky suggests that we should focus instead on the development of what he calls "digital wisdom." Arguing that digital technology can make us not just smarter but truly wiser, Prensky…

  12. Gender Equity. IDRA Focus.

    ERIC Educational Resources Information Center

    IDRA Newsletter, 1996

    1996-01-01

    This newsletter includes five articles on gender equity and related issues in education, with particular reference to the education of Hispanic girls. "IDRA's MIJA Program Expands" (Aurora Yanez-Perez) describes a program for sixth-grade Hispanic girls that promotes awareness of science- and math-related careers, provides training in science and…

  13. Gender Object Identification Test.

    ERIC Educational Resources Information Center

    Sigmon, Scott B.

    This test was designed primarily for the purpose of assisting social psychologists in researching sex roles and/or sex differences when a nonverbal instrument is desired. The hypothesis was that some objects would be easier for members of one gender to name. The subjects were 30 female and 20 male undergraduate students. Pictures of 65 commercial…

  14. [Gender differences in depression].

    PubMed

    Karger, A

    2014-09-01

    Depression is one of the most prevalent and debilitating diseases. In recent years there has been increased awareness of sex- and gender-specific issues in depression. This narrative review presents and discusses differences in prevalence, symptom profile, age at onset and course, comorbidity, biological and psychosocial factors, the impact of sexual stereotyping, help-seeking, emotion regulation and doctor-patient communication. Typically, women are diagnosed with depression twice as often as men, and their disease follows a more chronic course. Comorbid anxiety is more prevalent in women, whereas comorbid alcohol abuse is a major concern in men. Sucide rates for men are between three and five times higher compared with women. Although there are different symptom profiles in men and women, it is difficult to define a gender-specific symptom profile. Socially mediated gender roles have a significant impact on psychosocial factors associated with risk, sickness behavior and coping strategies. In general, too little attention has been paid to the definition and handling of depression and the gender-related requirements it makes on the healthcare system. PMID:25070409

  15. Genre and Gender.

    ERIC Educational Resources Information Center

    Curti, Lidia

    This paper begins by discussing the difference between genre and gender, defining the former as the study of a systemic totality, and the latter as the split in the totality, reversal, upturning, and break-up of any systemic logic. Also discussed are (1) the difference between nature and culture, and the quarrel between essentialist and…

  16. Closing the Gender Gap.

    ERIC Educational Resources Information Center

    Sanders, Jo

    1993-01-01

    Girls' avoidance of computers seems downright mysterious. There is no Big Culprit, but teachers and administrators might ponder the effects of gender-biased classroom practices, social activities, and TV commercials and role-models. This article points out some computer-equity-program successes in several states. A sidebar describes…

  17. Education and Gender Discrimination

    ERIC Educational Resources Information Center

    Sumi, V. S.

    2012-01-01

    This paper discusses the status of women education in present education system and some measures to overcome the lags existing. Discrimination against girls and women in the developing world is a devastating reality. It results in millions of individual tragedies, which add up to lost potential for entire countries. Gender bias in education is an…

  18. Mathematics and Gender.

    ERIC Educational Resources Information Center

    Fennema, Elizabeth, Ed.; Leder, Gilah C., Ed.

    This book reports on various studies that have increased our understanding of why females and males learn different kinds and amounts of mathematics. In particular, this book explicates the Autonomous Learning Behavior model, proposed by Fennema and Peterson, which is a possible explanation of the development of gender differences in mathematics.…

  19. Gender and Bilinguals' Creativity.

    ERIC Educational Resources Information Center

    Baker, Wendy

    2001-01-01

    Using Biber's multidimensional analysis (1988) to examine a large corpus of world English literatures written in Indian, West African, Britain, Anglo-American, and Mexican American varieties of English, examines whether quantitative analyses can also be insightful and useful in the examination of the influence of gender on language and in…

  20. Gender and Job Values.

    ERIC Educational Resources Information Center

    Marini, Margaret Mooney; And Others

    1996-01-01

    Discovers distinct differences and a few similarities between men and women concerning values and expectations associated with employment. Women attach greater importance to intrinsic, altruistic, and social rewards. Earlier research suggested significant gender differences regarding extrinsic rewards; however, this category revealed no…

  1. Data on gender

    NASA Astrophysics Data System (ADS)

    Gehring, Gillian

    2012-05-01

    In her Forum article "Mending the broken pipe" (April pp16-17), Lesley Cohen showed very encouraging data on the increasing numbers of female physicists at Imperial College London, which is one of the leaders in driving gender equality among academics in the UK.

  2. Genders, Mathematics, and Feminisms.

    ERIC Educational Resources Information Center

    Damarin, Suzanne

    Historical studies reveal that mathematics has been claimed as a private domain by men, while studies of the popular press document that women and girls are considered incompetent in that field. The study of gender and mathematics as viewed through feminism can create a new reading which exposes hidden assumptions, unwarranted conclusions, and…

  3. Gender and Distance Learning.

    ERIC Educational Resources Information Center

    Brunner, Cornelia

    This article examines distance learning from a gender perspective. In any new area of enterprise, expectations have an important effect on planning, implementation, and evaluation. When it comes to distance learning, a variety of images of what this exciting new technology will look like and what it can empower us to achieve will determine how we…

  4. Gender Differences in Creativity

    ERIC Educational Resources Information Center

    Baer, John; Kaufman, James C.

    2008-01-01

    Research on gender differences in creativity, including creativity test scores, creative achievements, and self-reported creativity is reviewed, as are theories that have been offered to explain such differences and available evidence that supports or refutes such theories. This is a difficult arena in which to conduct research, but there is a…

  5. Gender and Academic Integrity.

    ERIC Educational Resources Information Center

    Hendershott, Anne; Drinan, Patrick F.; Cross, Megan

    1999-01-01

    Investigates the academic integrity climate of a mid-sized, comprehensive, private university. Seeks to assess gender differences in motivations surrounding cheating behaviors among 532 undergraduate students. Findings indicate that while both males and females are reluctant to report instances of academic dishonesty that they witness, there…

  6. Gender and Publishing.

    ERIC Educational Resources Information Center

    Enos, Theresa

    1990-01-01

    Summarizes and updates an earlier descriptive survey of male-to-female publishing ratios in rhetoric and composition journals. Expands the earlier survey to see how much collaborative work is being published and how much is male coauthored, female coauthored, or mixed gender. (RS)

  7. Gender Issues within Higher Education

    ERIC Educational Resources Information Center

    European Students' Union (NJ1), 2008

    2008-01-01

    This handbook functions as a crown on the European Students' Union's work on gender equality over the past two years. Since the establishment of the Gender Equality Committee, a lot of work has been done to improve gender equality in higher education generally, and in student unions more particularly. This handbook gathers the experiences and…

  8. Gender Constancy and Television Viewing.

    ERIC Educational Resources Information Center

    Luecke-Aleksa, Diane; And Others

    1995-01-01

    Explored gender constancy's interaction with television viewing, using videotapes of television viewing and viewing diaries for 5-year olds. Gender-constant boys focused on more male characters and watched more action and sports programs than preconstant boys. Gender-constant girls viewed more action programming than preconstant girls. Acquisition…

  9. Trends in Global Gender Inequality

    ERIC Educational Resources Information Center

    Dorius, Shawn F.; Firebaugh, Glenn

    2010-01-01

    This study investigates trends in gender inequality throughout the world. Using data encompassing a large majority of the world's population, we examine trends in recent decades for key indicators of gender inequality in education, mortality, political representation and economic activity. We find that gender inequality is declining in virtually…

  10. Troubling Gender through Mail Art

    ERIC Educational Resources Information Center

    McGregor, Catherine

    2015-01-01

    A persistent and troubling trend in teacher education programmes is how gender is constructed heteronormatively. Finding ways that challenge novice teacher thinking about gender and gender identities has proven to be difficult ([Grace, A. P., and K. Wells. 2006. "The Quest for a Queer Inclusive Cultural Ethics: Setting Directions for…

  11. Gender Discrimination in Jessica's Career.

    ERIC Educational Resources Information Center

    Cook, Ellen Piel

    1997-01-01

    Focuses on the sexual harassment and other gender-related difficulties faced by a Chinese-American woman. Profiles her encounters with gender discrimination and how it hindered career advancement and led to professional isolation. Relates how this case study can be used to sensitize workers to gender discrimination. (RJM)

  12. Bringing up Gender: Academic Abjection?

    ERIC Educational Resources Information Center

    Henderson, Emily F.

    2014-01-01

    The principal questions raised in this article are: what does it mean to bring up the topic of gender in a space where it is not known, and how can this moment of bringing up gender--or not bringing it up--be conceptualised? The article departs from the thoughts and questions that were provoked by an interview conducted with a Gender Studies…

  13. Gender Aspects of Human Security

    ERIC Educational Resources Information Center

    Moussa, Ghada

    2008-01-01

    The chapter deals with the gender dimensions in human security through focusing on the relationship between gender and human security, first manifested in international declarations and conventions, and subsequently evolving in world women conferences. It aims at analysing the various gender aspects in its relation to different human security…

  14. Gender norms affect adolescents.

    PubMed

    Barnett, B

    1997-01-01

    Gender roles of men and women are determined by the society they live in. Many organizations that work with adolescents and young adults are incorporating a gender perspective into sex education, service delivery, and provider training programs in order to improve the reproductive health of their target groups. Many societies place a higher value on males than females. In sub-Saharan African countries girls are expelled from school if they become pregnant. In Egypt 86% of 2300 women interviewed believed the beatings by husband are justified under some circumstances, and 31% reported being beaten during pregnancy. A study of 128 adolescents in Peru and 108 in Columbia found that 60% of them had been sexually abused within the previous year. Female circumcision jeopardizes reproductive health, yet some 2 million girls undergo the procedure annually. In Thailand, among more than 100 factory workers 15-24 years old, the majority of men said premarital intercourse was accepted, while young women said premarital intercourse was unacceptable. Many programs that incorporate gender have begun projects that empower girls. Better Life Options administered by the Center for Development and Population Activities (CEDPA) provides information about sexuality, reproductive health, family planning and communication skills. The Young Men's Clinic, located in New York, aims to provide reproductive health services for men while also doing screening for tuberculosis or sickle-cell anemia. A report from the United Nations Population Fund states that men's services can be provided by minor adaptations to existing facilities. In Argentina the Foundation for Study and Research on Women offers education sessions on family planning and STDs to 50-100 secondary school students. In Gujarat, India, the Center for Health Education, Training and Nutrition Awareness incorporates gender into its health education workshops for young people ages 11-18. In these programs more equality in gender roles

  15. Digital Sensor Technology

    SciTech Connect

    Ted Quinn; Jerry Mauck; Richard Bockhorst; Ken Thomas

    2013-07-01

    The nuclear industry has been slow to incorporate digital sensor technology into nuclear plant designs due to concerns with digital qualification issues. However, the benefits of digital sensor technology for nuclear plant instrumentation are substantial in terms of accuracy, reliability, availability, and maintainability. This report demonstrates these benefits in direct comparisons of digital and analog sensor applications. It also addresses the qualification issues that must be addressed in the application of digital sensor technology.

  16. Brain investigation and brain conceptualization

    PubMed Central

    Redolfi, Alberto; Bosco, Paolo; Manset, David; Frisoni, Giovanni B.

    Summary The brain of a patient with Alzheimer’s disease (AD) undergoes changes starting many years before the development of the first clinical symptoms. The recent availability of large prospective datasets makes it possible to create sophisticated brain models of healthy subjects and patients with AD, showing pathophysiological changes occurring over time. However, these models are still inadequate; representations are mainly single-scale and they do not account for the complexity and interdependence of brain changes. Brain changes in AD patients occur at different levels and for different reasons: at the molecular level, changes are due to amyloid deposition; at cellular level, to loss of neuron synapses, and at tissue level, to connectivity disruption. All cause extensive atrophy of the whole brain organ. Initiatives aiming to model the whole human brain have been launched in Europe and the US with the goal of reducing the burden of brain diseases. In this work, we describe a new approach to earlier diagnosis based on a multimodal and multiscale brain concept, built upon existing and well-characterized single modalities. PMID:24139654

  17. Audio-visual gender recognition

    NASA Astrophysics Data System (ADS)

    Liu, Ming; Xu, Xun; Huang, Thomas S.

    2007-11-01

    Combining different modalities for pattern recognition task is a very promising field. Basically, human always fuse information from different modalities to recognize object and perform inference, etc. Audio-Visual gender recognition is one of the most common task in human social communication. Human can identify the gender by facial appearance, by speech and also by body gait. Indeed, human gender recognition is a multi-modal data acquisition and processing procedure. However, computational multimodal gender recognition has not been extensively investigated in the literature. In this paper, speech and facial image are fused to perform a mutli-modal gender recognition for exploring the improvement of combining different modalities.

  18. Sex beyond the genitalia: The human brain mosaic.

    PubMed

    Joel, Daphna; Berman, Zohar; Tavor, Ido; Wexler, Nadav; Gaber, Olga; Stein, Yaniv; Shefi, Nisan; Pool, Jared; Urchs, Sebastian; Margulies, Daniel S; Liem, Franziskus; Hänggi, Jürgen; Jäncke, Lutz; Assaf, Yaniv

    2015-12-15

    Whereas a categorical difference in the genitals has always been acknowledged, the question of how far these categories extend into human biology is still not resolved. Documented sex/gender differences in the brain are often taken as support of a sexually dimorphic view of human brains ("female brain" or "male brain"). However, such a distinction would be possible only if sex/gender differences in brain features were highly dimorphic (i.e., little overlap between the forms of these features in males and females) and internally consistent (i.e., a brain has only "male" or only "female" features). Here, analysis of MRIs of more than 1,400 human brains from four datasets reveals extensive overlap between the distributions of females and males for all gray matter, white matter, and connections assessed. Moreover, analyses of internal consistency reveal that brains with features that are consistently at one end of the "maleness-femaleness" continuum are rare. Rather, most brains are comprised of unique "mosaics" of features, some more common in females compared with males, some more common in males compared with females, and some common in both females and males. Our findings are robust across sample, age, type of MRI, and method of analysis. These findings are corroborated by a similar analysis of personality traits, attitudes, interests, and behaviors of more than 5,500 individuals, which reveals that internal consistency is extremely rare. Our study demonstrates that, although there are sex/gender differences in the brain, human brains do not belong to one of two distinct categories: male brain/female brain. PMID:26621705

  19. Right Hemisphere Brain Damage

    MedlinePlus

    ... Language and Swallowing / Disorders and Diseases Right Hemisphere Brain Damage [ en Español ] What is right hemisphere brain ... right hemisphere brain damage ? What is right hemisphere brain damage? Right hemisphere brain damage (RHD) is damage ...

  20. Brain tumor - primary - adults

    MedlinePlus

    ... Vestibular schwannoma (acoustic neuroma) - adults; Meningioma - adults; Cancer - brain tumor (adults) ... Primary brain tumors include any tumor that starts in the brain. Primary brain tumors can start from brain cells, ...

  1. Brain radiation - discharge

    MedlinePlus

    Radiation - brain - discharge; Cancer-brain radiation; Lymphoma - brain radiation; Leukemia - brain radiation ... Decadron) while you are getting radiation to the brain. It may make you hungrier, cause leg swelling ...

  2. [Gender discourses and bioethics].

    PubMed

    Aparisi Miralles, Angela

    2014-01-01

    The purpose of this paper is to present some of the contributions of the gender discourse to the bioethical debate, specifically in the field of nursing. At the same time, it will explain the contribution of the different feminist theories to the recognition and respect of human dignity. Basically, it will describe the three fundamental models in the gender discourse: the egalitarian model, the difference model, and the model of reciprocity or complementarity. The starting point is that even though the first two models have made significant contributions in the field of bioethics, they have nonetheless brought with them some deficiencies and reductionisms inherent in their thinking. The complementarity model, on the contrary, when properly understood, allows for the combination of the principles of equality and difference between man and woman, which places it at a much more enriching standpoint within the bioethical debate. PMID:25329418

  3. Towards ensuring gender equity.

    PubMed

    Basu, A

    1996-01-01

    All people should participate in the development process. Many, however, remain excluded from the benefits of development. For example, women are privy to only a small share of developmental opportunities. The goals of equality, development, and peace were stated during the Fourth World Conference on Women held in Beijing in September 1995. The author considers whether women truly have equitable access to literacy, education, food, nutrition, health, employment, and the political and economic decision making process. She stresses that the goals pronounced at the Fourth World Conference on Women must be backed up with the necessary resources, including institutions established at the local, state, and national levels to ensure that the objectives are implemented and the implementation is monitored. The author further argues that in order for women to achieve equality with men, all girls must have access to primary and secondary schools; basic literacy is inadequate. Moreover, gender stereotyping must be avoided and gender sensitization ensured at all levels. PMID:12347385

  4. Brain Development

    MedlinePlus

    ... new neural connections every second. This growing brain development is influenced by many factors, including a child’s relationships, experiences and environment. Learn more about the crucial role you play ...

  5. Brain herniation

    MedlinePlus

    Ling GSF. Traumatic brain injury and spinal cord injury. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 24th ed. Philadelphia, PA: Elsevier Saunders; 2011:chap 406. Stippler M. Trauma of ...

  6. [Gender in view].

    PubMed

    1998-03-01

    A manual recently published by Mexico¿s National System for Integral Development of the Family, ¿The gender perspective: a tool for constructing equity between men and women¿, is intended to put into practice the Cairo accords. The gender perspective has been applied in recent years to interpretation of the situation of women in past and present societies. Gender is not sex; it is the manner in which societies have symbolized and understood relations between men and women. The manual concludes that the main difference between the sexes beyond the obvious genital differences is in the greater musculature and strength of males. In contemporary societies, these attributes are less needed than technical knowledge and skills, which may be obtained by either sex. Economic evolution has led increasing numbers of women to work outside their homes. The gender roles assigned for millennia, and accepted as the natural order, are no longer adequate. The power of men has been preserved by attributing the gigantic cultural differences resulting from specialization into male and female roles to the small physical differences between the sexes. Governments have slowly established legal equity, but discrimination against women has not disappeared in the workplace, public offices, or any other social sphere, and their incorporation into the work force has left them with the double workday as they continue to perform the great bulk of domestic work. It is therefore necessary to seek equity as well as equality, understood as the creation of equivalent opportunities for men and women. PMID:12349308

  7. The Two-Brains Hypothesis: Towards a guide for brain-brain and brain-machine interfaces.

    PubMed

    Goodman, G; Poznanski, R R; Cacha, L; Bercovich, D

    2015-09-01

    Great advances have been made in signaling information on brain activity in individuals, or passing between an individual and a computer or robot. These include recording of natural activity using implants under the scalp or by external means or the reverse feeding of such data into the brain. In one recent example, noninvasive transcranial magnetic stimulation (TMS) allowed feeding of digitalized information into the central nervous system (CNS). Thus, noninvasive electroencephalography (EEG) recordings of motor signals at the scalp, representing specific motor intention of hand moving in individual humans, were fed as repetitive transcranial magnetic stimulation (rTMS) at a maximum intensity of 2.0[Formula: see text]T through a circular magnetic coil placed flush on each of the heads of subjects present at a different location. The TMS was said to induce an electric current influencing axons of the motor cortex causing the intended hand movement: the first example of the transfer of motor intention and its expression, between the brains of two remote humans. However, to date the mechanisms involved, not least that relating to the participation of magnetic induction, remain unclear. In general, in animal biology, magnetic fields are usually the poor relation of neuronal current: generally "unseen" and if apparent, disregarded or just given a nod. Niels Bohr searched for a biological parallel to complementary phenomena of physics. Pertinently, the two-brains hypothesis (TBH) proposed recently that advanced animals, especially man, have two brains i.e., the animal CNS evolved as two fundamentally different though interdependent, complementary organs: one electro-ionic (tangible, known and accessible), and the other, electromagnetic (intangible and difficult to access) - a stable, structured and functional 3D compendium of variously induced interacting electro-magnetic (EM) fields. Research on the CNS in health and disease progresses including that on brain-brain

  8. Gender dysphoria in adolescence.

    PubMed

    Leibowitz, Scott; de Vries, Annelou L C

    2016-01-01

    Adolescents presenting with gender-related concerns are increasingly seeking support from providers from a variety of disciplines within health care settings across the world. For those treating young people who meet the criteria for the DSM 5 diagnosis of gender dysphoria (GD), complex decisions in clinical care are common. Defining best practice with this population with respect to interventions that span mental health, physical, and surgical domains can be challenging, given a relative dearth of empirical data available; yet practice guidelines have emerged from different professional organizations which can aid with this. For this review paper, a broad literature search was performed to identify relevant studies pertaining to the care of adolescents with GD. In addition, an overview of trends in clinical practice, including shifts in conceptualization of how clinicians and patients define care that is considered affirming when working with this population, is described. This paper explores the characteristics of referral patterns to specialized clinics, provides a brief overview of gender identity development in adolescence, and then describes the phenomenology of known aetiological factors and co-occurring psychiatric issues in adolescents with GD. Additionally, clinical management considerations that detail assessment aims and common treatment interventions across disciplines will be explored. PMID:26828376

  9. Digital image processing.

    PubMed

    Seeram, Euclid

    2004-01-01

    Digital image processing is now commonplace in radiology, nuclear medicine and sonography. This article outlines underlying principles and concepts of digital image processing. After completing this article, readers should be able to: List the limitations of film-based imaging. Identify major components of a digital imaging system. Describe the history and application areas of digital image processing. Discuss image representation and the fundamentals of digital image processing. Outline digital image processing techniques and processing operations used in selected imaging modalities. Explain the basic concepts and visualization tools used in 3-D and virtual reality imaging. Recognize medical imaging informatics as a new area of specialization for radiologic technologists. PMID:15352557

  10. Brain imaging and brain function

    SciTech Connect

    Sokoloff, L.

    1985-01-01

    This book is a survey of the applications of imaging studies of regional cerebral blood flow and metabolism to the investigation of neurological and psychiatric disorders. Contributors review imaging techniques and strategies for measuring regional cerebral blood flow and metabolism, for mapping functional neural systems, and for imaging normal brain functions. They then examine the applications of brain imaging techniques to the study of such neurological and psychiatric disorders as: cerebral ischemia; convulsive disorders; cerebral tumors; Huntington's disease; Alzheimer's disease; depression and other mood disorders. A state-of-the-art report on magnetic resonance imaging of the brain and central nervous system rounds out the book's coverage.

  11. Gender differences in human single neuron responses to male emotional faces

    PubMed Central

    Newhoff, Morgan; Treiman, David M.; Smith, Kris A.; Steinmetz, Peter N.

    2015-01-01

    Well-documented differences in the psychology and behavior of men and women have spurred extensive exploration of gender's role within the brain, particularly regarding emotional processing. While neuroanatomical studies clearly show differences between the sexes, the functional effects of these differences are less understood. Neuroimaging studies have shown inconsistent locations and magnitudes of gender differences in brain hemodynamic responses to emotion. To better understand the neurophysiology of these gender differences, we analyzed recordings of single neuron activity in the human brain as subjects of both genders viewed emotional expressions. This study included recordings of single-neuron activity of 14 (6 male) epileptic patients in four brain areas: amygdala (236 neurons), hippocampus (n = 270), anterior cingulate cortex (n = 256), and ventromedial prefrontal cortex (n = 174). Neural activity was recorded while participants viewed a series of avatar male faces portraying positive, negative or neutral expressions. Significant gender differences were found in the left amygdala, where 23% (n = 15∕66) of neurons in men were significantly affected by facial emotion, vs. 8% (n = 6∕76) of neurons in women. A Fisher's exact test comparing the two ratios found a highly significant difference between the two (p < 0.01). These results show specific differences between genders at the single-neuron level in the human amygdala. These differences may reflect gender-based distinctions in evolved capacities for emotional processing and also demonstrate the importance of including subject gender as an independent factor in future studies of emotional processing by single neurons in the human amygdala. PMID:26441597

  12. Gender incongruence/gender dysphoria and its classification history.

    PubMed

    Beek, Titia F; Cohen-Kettenis, Peggy T; Kreukels, Baudewijntje P C

    2016-01-01

    In this article we discuss the changes in the Diagnostic and Statistical Manual of Mental Disorders (DSM) classification of gender identity-related conditions over time, and indicate how these changes were associated with the changes in conceptualization. A diagnosis of 'transsexualism' appeared first in DSM-III in 1980. This version also included a childhood diagnosis: gender identity disorder of childhood. As research about gender incongruence/gender dysphoria increased, the terminology, placement and criteria were reviewed in successive versions of the DSM. Changes in various aspects of the diagnosis, however, were not only based on research. Social and political factors contributed to the conceptualization of gender incongruence/gender dysphoria as well. PMID:26782319

  13. Gender reassignment surgery: an overview.

    PubMed

    Selvaggi, Gennaro; Bellringer, James

    2011-05-01

    Gender reassignment (which includes psychotherapy, hormonal therapy and surgery) has been demonstrated as the most effective treatment for patients affected by gender dysphoria (or gender identity disorder), in which patients do not recognize their gender (sexual identity) as matching their genetic and sexual characteristics. Gender reassignment surgery is a series of complex surgical procedures (genital and nongenital) performed for the treatment of gender dysphoria. Genital procedures performed for gender dysphoria, such as vaginoplasty, clitorolabioplasty, penectomy and orchidectomy in male-to-female transsexuals, and penile and scrotal reconstruction in female-to-male transsexuals, are the core procedures in gender reassignment surgery. Nongenital procedures, such as breast enlargement, mastectomy, facial feminization surgery, voice surgery, and other masculinization and feminization procedures complete the surgical treatment available. The World Professional Association for Transgender Health currently publishes and reviews guidelines and standards of care for patients affected by gender dysphoria, such as eligibility criteria for surgery. This article presents an overview of the genital and nongenital procedures available for both male-to-female and female-to-male gender reassignment. PMID:21487386

  14. Robotics as science (re)form: Exploring power, learning and gender(ed) identity formation in a "community of practice"

    NASA Astrophysics Data System (ADS)

    Hurner, Sheryl Marie

    "Robotics as Science (re)Form" utilizes qualitative research methods to examine the career trajectories and gender identity formation of female youth participating as members of an all-girl, academic team within the male-dominated environment of the FIRST Robotics competition. Following the constant comparative approach (Glaser & Strauss, 1967), my project relies upon triangulating ethnographic data drawn from extensive field notes, semi-structured interviews, and digital and video imagery compiled over two years of participant observation. Drawing upon the sociolinguistic "community of practice" (CoP) framework (Eckert & McConnell-Ginet, 1992; Lave & Wenger, 1991; Wenger, 1998), this study maps the range of gendered "identities" available to girls involved in non-traditional academic and occupational pursuits within a local context, and reveals the nature, structure and impact of power operating within this CoP, a significantly underdeveloped construct within the language and gender literature. These research findings (1) contribute to refining theories of situated or problem based learning with a focus on female youth (Lave & Wenger, 1991; Wenger, 1998); (2) reveal affordances and barriers within the local program design that enable (and preclude) women and minority youth entering the engineering pipeline; and (3) enrich our understanding of intragroup language and gendered "practices" to counter largely essentializing generalizations based upon quantitative analysis. Keywords: Robotics, gender, identity formation, science, STEM, communities of practice

  15. Time trends (1998-2007) in brain cancer incidence rates in relation to mobile phone use in England.

    PubMed

    de Vocht, Frank; Burstyn, Igor; Cherrie, John W

    2011-07-01

    Mobile phone use in the United Kingdom and other countries has risen steeply since the early 1990's when the first digital mobile phones were introduced. There is an ongoing controversy about whether radio frequency (RF) exposure from mobile phones increases the risk of brain cancer. However, given the widespread use and nearly two decades elapsing since mobile phones were introduced, an association should have produced a noticeable increase in the incidence of brain cancer by now. Trends in rates of newly diagnosed brain cancer cases in England between 1998 and 2007 were examined. There were no time trends in overall incidence of brain cancers for either gender, or any specific age group. Systematic increases in rates for cancers of the temporal lobe in men (0.04 new cases/year) and women (0.02/year) were observed, along with decreases in the rates of cancers of the parietal lobe (-0.03/year), cerebrum (-0.02/year) and cerebellum (-0.01/year) in men only. The increased use of mobile phones between 1985 and 2003 has not led to a noticeable change in the incidence of brain cancer in England between 1998 and 2007. The observed increase in the rate of cancers in the temporal lobe, if caused by mobile phone use, would constitute <1 additional case per 100,000 people in that period. These data do not indicate a pressing need to implement a precautionary principle by means of population-wide interventions to reduce RF exposure from mobile phones. PMID:21280060

  16. Brain templates and atlases.

    PubMed

    Evans, Alan C; Janke, Andrew L; Collins, D Louis; Baillet, Sylvain

    2012-08-15

    The core concept within the field of brain mapping is the use of a standardized, or "stereotaxic", 3D coordinate frame for data analysis and reporting of findings from neuroimaging experiments. This simple construct allows brain researchers to combine data from many subjects such that group-averaged signals, be they structural or functional, can be detected above the background noise that would swamp subtle signals from any single subject. Where the signal is robust enough to be detected in individuals, it allows for the exploration of inter-individual variance in the location of that signal. From a larger perspective, it provides a powerful medium for comparison and/or combination of brain mapping findings from different imaging modalities and laboratories around the world. Finally, it provides a framework for the creation of large-scale neuroimaging databases or "atlases" that capture the population mean and variance in anatomical or physiological metrics as a function of age or disease. However, while the above benefits are not in question at first order, there are a number of conceptual and practical challenges that introduce second-order incompatibilities among experimental data. Stereotaxic mapping requires two basic components: (i) the specification of the 3D stereotaxic coordinate space, and (ii) a mapping function that transforms a 3D brain image from "native" space, i.e. the coordinate frame of the scanner at data acquisition, to that stereotaxic space. The first component is usually expressed by the choice of a representative 3D MR image that serves as target "template" or atlas. The native image is re-sampled from native to stereotaxic space under the mapping function that may have few or many degrees of freedom, depending upon the experimental design. The optimal choice of atlas template and mapping function depend upon considerations of age, gender, hemispheric asymmetry, anatomical correspondence, spatial normalization methodology and disease

  17. Gendered education in a gendered world: looking beyond cosmetic solutions to the gender gap in science

    NASA Astrophysics Data System (ADS)

    Sinnes, Astrid T.; Løken, Marianne

    2014-06-01

    Young people in countries considered to be at the forefront of gender equity still tend to choose very traditional science subjects and careers. This is particularly the case in science, technology, engineering and mathematics subjects (STEM), which are largely male dominated. This article uses feminist critiques of science and science education to explore the underlying gendered assumptions of a research project aiming to contribute to improving recruitment, retention and gender equity patterns in STEM educations and careers. Much research has been carried out to understand this gender gap phenomenon as well as to suggest measures to reduce its occurrence. A significant portion of this research has focused on detecting the typical "female" and "male" interest in science and has consequently suggested that adjustments be made to science education to cater for these interests. This article argues that adjusting science subjects to match perceived typical girls' and boys' interests risks being ineffective, as it contributes to the imposition of stereotyped gender identity formation thereby also imposing the gender differences that these adjustments were intended to overcome. This article also argues that different ways of addressing gender issues in science education themselves reflects different notions of gender and science. Thus in order to reduce gender inequities in science these implicit notions of gender and science have to be made explicit. The article begins with an overview of the current situation regarding gender equity in some so- called gender equal countries. We then present three perspectives from feminist critiques of science on how gender can be seen to impact on science and science education. Thereafter we analyze recommendations from a contemporary research project to explore which of these perspectives is most prevalent.

  18. Brain death.

    PubMed

    Wijdicks, Eelco F M

    2013-01-01

    The diagnosis of brain death should be based on a simple premise. If every possible confounder has been excluded and all possible treatments have been tried or considered, irreversible loss of brain function is clinically recognized as the absence of brainstem reflexes, verified apnea, loss of vascular tone, invariant heart rate, and, eventually, cardiac standstill. This condition cannot be reversed - not even partly - by medical or surgical intervention, and thus is final. Many countries in the world have introduced laws that acknowledge that a patient can be declared brain-dead by neurologic standards. The U.S. law differs substantially from all other brain death legislation in the world because the U.S. law does not spell out details of the neurologic examination. Evidence-based practice guidelines serve as a standard. In this chapter, I discuss the history of development of the criteria, the current clinical examination, and some of the ethical and legal issues that have emerged. Generally, the concept of brain death has been accepted by all major religions. But patients' families may have different ideas and are mostly influenced by cultural attitudes, traditional customs, and personal beliefs. Suggestions are offered to support these families. PMID:24182378

  19. Digital subtraction laryngography

    SciTech Connect

    Brown, B.W.; Enzmann, D.R.; Hopp, M.L.; Castellino, R.A.

    1983-06-01

    Digital subtraction laryngography was used to evaluate laryngeal function in 8 patients: 4 with normal larynxes and 4 with laryngeal disease. Subtracted digital images provided a dynamic display of the extent and symmetry of vocal cord excursions and pyriform sinus inflation, and the vocal cord resting position was also clearly depicted. The technical details of digital subtraction laryngography and its application are described.

  20. Bridging the Digital Divide

    ERIC Educational Resources Information Center

    Clarke, Alan; Milner, Helen; Killer, Terry; Dixon, Genny

    2008-01-01

    As the Government publishes its action plan for consultation on digital inclusion, the authors consider some of the challenges and opportunities for the delivery of digital inclusion. Clarke argues that digital inclusion requires more than access to technology or the skills to use it effectively, it demands information and media literacy. Milner…

  1. Digital Ink and Notetaking

    ERIC Educational Resources Information Center

    Colwell, Kenneth E.

    2004-01-01

    Tablet PCs and graphics tablets employ digital ink technology. In this paper the author introduces the reader to digital ink technology with the aim of promoting its use in various instructional or training settings, with the goal of improving instructor-learner dialogue and student learning. The potential of digital ink for improved instructional…

  2. Reconceptualising Critical Digital Literacy

    ERIC Educational Resources Information Center

    Pangrazio, Luciana

    2016-01-01

    While it has proved a useful concept during the past 20 years, the notion of "critical digital literacy" requires rethinking in light of the fast-changing nature of young people's digital practices. This paper contrasts long-established notions of "critical digital literacy" (based primarily around the critical consumption of…

  3. Digital Literacy. Research Brief

    ERIC Educational Resources Information Center

    Williamson, Ronald

    2011-01-01

    21st Century students need a complex set of skills to be successful in a digital environment. Digital literacy, similar to traditional definitions of literacy, is a set of skills students use to locate, organize, understand, evaluate and create information. The difference is that it occurs in an environment where a growing set of digital tools…

  4. Digital Language Death

    PubMed Central

    Kornai, András

    2013-01-01

    Of the approximately 7,000 languages spoken today, some 2,500 are generally considered endangered. Here we argue that this consensus figure vastly underestimates the danger of digital language death, in that less than 5% of all languages can still ascend to the digital realm. We present evidence of a massive die-off caused by the digital divide. PMID:24167559

  5. Mass Digitization of Books

    ERIC Educational Resources Information Center

    Coyle, Karen

    2006-01-01

    Mass digitization of the bound volumes that we generally call "books" has begun, and, thanks to the interest in Google and all that it does, it is getting widespread media attention. The Open Content Alliance (OCA), a library initiative formed after Google announced its library book digitization project, has brought library digitization projects…

  6. NEXUS: Digitizing Higher Education.

    ERIC Educational Resources Information Center

    Kirk, Camille

    2000-01-01

    Discussion of digital technology in the context of higher education planning considers how these technologies change teaching; the digital divide; the costs of information technology; hard wiring the campus; material consequences of information technology; digitally enabled crimes and misdemeanors; and libraries and scholarly publishing. Concludes…

  7. Digital language death.

    PubMed

    Kornai, András

    2013-01-01

    Of the approximately 7,000 languages spoken today, some 2,500 are generally considered endangered. Here we argue that this consensus figure vastly underestimates the danger of digital language death, in that less than 5% of all languages can still ascend to the digital realm. We present evidence of a massive die-off caused by the digital divide. PMID:24167559

  8. Antecedents and sex/gender differences in youth suicidal behavior

    PubMed Central

    Rhodes, Anne E; Boyle, Michael H; Bridge, Jeffrey A; Sinyor, Mark; Links, Paul S; Tonmyr, Lil; Skinner, Robin; Bethell, Jennifer M; Carlisle, Corine; Goodday, Sarah; Hottes, Travis Salway; Newton, Amanda; Bennett, Kathryn; Sundar, Purnima; Cheung, Amy H; Szatmari, Peter

    2014-01-01

    Suicide is the second leading cause of death in youth globally; however, there is uncertainty about how best to intervene. Suicide rates are typically higher in males than females, while the converse is true for suicide attempts. We review this “gender paradox” in youth, and in particular, the age-dependency of these sex/gender differences and the developmental mechanisms that may explain them. Epidemiologic, genetic, neurodevelopmental and psychopathological research have identified suicidal behaviour risks arising from genetic vulnerabilities and sex/gender differences in early adverse environments, neurodevelopment, mental disorder and their complex interconnections. Further, evolving sex-/gender-defined social expectations and norms have been thought to influence suicide risk. In particular, how youth perceive and cope with threats and losses (including conforming to others’ or one’s own expectations of sex/gender identity) and adapt to pain (through substance use and help-seeking behaviours). Taken together, considering brain plasticity over the lifespan, these proposed antecedents to youth suicide highlight the importance of interventions that alter early environment(s) (e.g., childhood maltreatment) and/or one’s ability to adapt to them. Further, such interventions may have more enduring protective effects, for the individual and for future generations, if implemented in youth. PMID:25540727

  9. Aggressiveness and brain amines in pigs fed the ß-adrenoreceptor agonist Ractopamine

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The objectives of this study were to evaluate the effects of the widely used feed additive Ractopamine (RAC), gender and social rank on aggressiveness and concentrations of brain amines in finishing pigs. Thirty-two barrows and 32 gilts (4 pigs/pen/gender) were fed either control or RAC (5 mg/kg/2 w...

  10. Eyeglasses and gender stereotypes.

    PubMed

    Terry, R L

    1989-10-01

    Under the guise of forming impressions of a job applicant in a hiring interview, subjects rated a videotaped male or female stimulus person (SP) on several gender stereotypical and task relevant traits. In one condition, the SP's wore eyeglasses, and in the other condition they did not. Eyeglasses, especially when worn by the stimulus male, were associated with feminine stereotypes and positive task relevant attributes. The results were interpreted to suggest that men who wear eyeglasses may be the target of some negative social judgments but also redeeming task relevant attributes, whereas women who wear eyeglasses are more likely to be the target of only negative social judgments. PMID:2587035

  11. Thermoimaging of the brain.

    PubMed

    Shevelev, I A; Tsicalov, E N; Gorbach, A M; Budko, K P; Sharaev, G A

    1993-01-01

    A new method of neuroimaging is proposed that is based on the recording of weak changes in infra-red radiation from the brain. Thermoencephaloscopy (TES) uses a combination of thermovision and digital image processing techniques and allows one to make a dynamic investigation of the thermal fields of the cerebral cortex through an unopened skull. Today the method is characterized by: (i) differential thermosensitivity of up to 0.002 degrees C; (ii) instrumental temporal resolution 40 ms (25 thermomaps/s); (iii) time of the temperature measurement in the part of an object that correspondes to one pixel on digital thermomap is equal to 2.4 microseconds; (iv) instrumental spatial resolution of up to 70 microns/pixel; and (v) the thermomap size is 10880 pixels (128 x 85). TES allows detection of an appearance and study of topography and dynamics of the small (from 140 to 300 microns) and precisely localized zones of activation or deactivation of the cerebral cortex that are modally and regionally specific with respect to stimuli modality and parameters and to the state of an animal. Up to now such studies were performed with white rats, rabbits, cats, monkeys and humans under different kinds of sensory stimulation, motor tasks, conditioning (associative learning). Fast thermowaves spreading over the brain cortex along specific trajectories were revealed under sensory stimulation. The mechanisms of the recorded phenomena are discussed: (i) joule heating produced by ion currents through membranes of activated neurones; (ii) metabolic thermoproduction; (iii) thermal convection by the local cerebral blood flow; and (iv) thermodipole formation in the cortical foci with changed lCBF. PMID:8459722

  12. Organic brain syndrome

    MedlinePlus

    OBS; Organic mental disorder (OMS); Chronic organic brain syndrome ... Listed below are disorders associated with OBS. Brain injury caused by ... the brain ( subarachnoid hemorrhage ) Blood clot inside the ...

  13. Sex beyond the genitalia: The human brain mosaic

    PubMed Central

    Joel, Daphna; Berman, Zohar; Tavor, Ido; Wexler, Nadav; Gaber, Olga; Stein, Yaniv; Shefi, Nisan; Pool, Jared; Urchs, Sebastian; Margulies, Daniel S.; Liem, Franziskus; Hänggi, Jürgen; Jäncke, Lutz; Assaf, Yaniv

    2015-01-01

    Whereas a categorical difference in the genitals has always been acknowledged, the question of how far these categories extend into human biology is still not resolved. Documented sex/gender differences in the brain are often taken as support of a sexually dimorphic view of human brains (“female brain” or “male brain”). However, such a distinction would be possible only if sex/gender differences in brain features were highly dimorphic (i.e., little overlap between the forms of these features in males and females) and internally consistent (i.e., a brain has only “male” or only “female” features). Here, analysis of MRIs of more than 1,400 human brains from four datasets reveals extensive overlap between the distributions of females and males for all gray matter, white matter, and connections assessed. Moreover, analyses of internal consistency reveal that brains with features that are consistently at one end of the “maleness-femaleness” continuum are rare. Rather, most brains are comprised of unique “mosaics” of features, some more common in females compared with males, some more common in males compared with females, and some common in both females and males. Our findings are robust across sample, age, type of MRI, and method of analysis. These findings are corroborated by a similar analysis of personality traits, attitudes, interests, and behaviors of more than 5,500 individuals, which reveals that internal consistency is extremely rare. Our study demonstrates that, although there are sex/gender differences in the brain, human brains do not belong to one of two distinct categories: male brain/female brain. PMID:26621705

  14. Digital Mammography and Digital Breast Tomosynthesis.

    PubMed

    Moseley, Tanya W

    2016-06-01

    Breast imaging technology has advanced significantly from the 1930s until the present. American women have a 1 in 8 chance of developing breast cancer. Mammography has been proven in multiple clinical trials to reduce breast cancer mortality. Although a mainstay of breast imaging and improved from film-screen mammography, digital mammography is not a perfect examination. Overlapping obscuring breast tissue limits mammographic interpretation. Breast digital tomosynthesis reduces and/or eliminates overlapping obscuring breast tissue. Although there are some disadvantages with digital breast tomosynthesis, this relatively lost-cost technology may be used effectively in the screening and diagnostic settings. PMID:27101241

  15. Gender Divide and Acceptance of Collaborative Web 2.0 Applications for Learning in Higher Education

    ERIC Educational Resources Information Center

    Huang, Wen-Hao David; Hood, Denice Ward; Yoo, Sun Joo

    2013-01-01

    Situated in the gender digital divide framework, this survey study investigated the role of computer anxiety in influencing female college students' perceptions toward Web 2.0 applications for learning. Based on 432 college students' "Web 2.0 for learning" perception ratings collected by relevant categories of "Unified Theory of Acceptance and Use…

  16. Lay Theories of Gender Identity Disorder

    PubMed Central

    Sen, Radhika

    2013-01-01

    This study examined lay theories regarding gender identity disorder (GID). Pilot interviews were completed with participants (n = 10) regarding their views on possible causes and treatments of GID. Participants (mainly young British people and students; n = 124) then completed a questionnaire that was based on the interviews and a review of the salient literature on lay theories. As hypothesized, participants believed most in biomedical causes and treatments of GID. Factor analysis (with varimax rotation) identified 4 factors in relation to causes of GID: upbringing and personal factors, pregnancy and brain abnormalities, environmental factors, and biomedical causes. Five factors that were identified in relation to the cure/treatment of GID were psychological assistance and personal factors, extreme medical and behavioral changes, alternative therapies, external factors, and medical treatments. The results indicated that participants neither agreed nor strongly disagreed about causes and cures regarding GID, but that these beliefs were logically related. Limitations, particularly of sampling, were considered. PMID:24059967

  17. Gender inequality in Russia: the perspective of participatory gender budgeting.

    PubMed

    Zakirova, Venera

    2014-11-01

    Gender-based discrimination is found in all economies in the world. Women's unpaid work accounts for about half of the world GDP, yet women remain under-valued and under-represented in national policies worldwide. The question of gender budgeting and citizens' participation in budgeting and governance processes has gained attention in recent years, but Russia is far from implementing these. Instead, blindness to gender issues dominates in national strategies and budgets. This paper explores these issues and looks in-depth at them in the decentralisation process in Bashkortostan, a central Russian republic. Civil society institutions whose role is to strengthen the links between government, civil society and the community in Bashkortostan, such as Public Chambers and Municipalities, lack the capacity to introduce participatory gender budgeting. As a result, no systematic participatory planning, let alone planning that is gender-sensitive, has taken place there. PMID:25555777

  18. Can Gender-Fair Language Reduce Gender Stereotyping and Discrimination?

    PubMed Central

    Sczesny, Sabine; Formanowicz, Magda; Moser, Franziska

    2016-01-01

    Gender-fair language (GFL) aims at reducing gender stereotyping and discrimination. Two principle strategies have been employed to make languages gender-fair and to treat women and men symmetrically: neutralization and feminization. Neutralization is achieved, for example, by replacing male-masculine forms (policeman) with gender-unmarked forms (police officer), whereas feminization relies on the use of feminine forms to make female referents visible (i.e., the applicant… he or she instead of the applicant… he). By integrating research on (1) language structures, (2) language policies, and (3) individual language behavior, we provide a critical review of how GFL contributes to the reduction of gender stereotyping and discrimination. Our review provides a basis for future research and for scientifically based policy-making. PMID:26869947

  19. Gender Equality and Violent Behavior: How Neighborhood Gender Equality Influences the Gender Gap in Violence

    PubMed Central

    Lei, Man-Kit; Simons, Ronald L.; Simons, Leslie Gordon; Edmond, Mary Bond

    2014-01-01

    Using a sample of 703 African American adolescents from the Family and Community Health Study (FACHS) along with census data from the year 2000, we examine the association between neighborhood-level gender equality and violence. We find that boys’ and girls’ violent behavior is unevenly distributed across neighborhood contexts. In particular, gender differences in violent behavior are less pronounced in gender-equalitarian neighborhoods compared to those characterized by gender inequality. We also find that the gender gap narrows in gender-equalitarian neighborhoods because boys’ rates of violence decrease whereas girls’ rates remain relatively low across neighborhoods. This is in stark contrast to the pessimistic predictions of theorists who argue that the narrowing of the gender gap in equalitarian settings is the result of an increase in girls’ violence. In addition, the relationship between neighborhood gender equality and violence is mediated by a specific articulation of masculinity characterized by toughness. Our results provide evidence for the use of gender-specific neighborhood prevention programs. PMID:24672996

  20. Gendered war and gendered peace: truth commissions and postconflict gender violence: lessons from South Africa.

    PubMed

    Borer, Tristan Anne

    2009-10-01

    That war is profoundly gendered has long been recognized by feminist international relations scholars. What is less recognized is that the postwar period is equally gendered. Currently undertheorized is how truth-seeking exercises in the aftermath of conflict should respond to this fact. What happens to women victims of war violence? The difficulties of foregrounding gendered wartime violence in truth telling are illustrated by the South African Truth and Reconciliation Commission. The article explores some consequences of the failure to uncover gendered truth, including its impact on the government's reparations policy, and continued "peacetime" violence perpetrated against women in South Africa. PMID:19706778

  1. Gender equality and violent behavior: how neighborhood gender equality influences the gender gap in violence.

    PubMed

    Lei, Man-Kit; Simons, Ronald L; Simons, Leslie Gordon; Edmond, Mary Bond

    2014-01-01

    Using a sample of 703 African American adolescents from the Family and Community Health Study (FACHS) along with census data from the year 2000, we examine the association between neighborhood-level gender equality and violence. We find that boys' and girls' violent behavior is unevenly distributed across neighborhood contexts. In particular, gender differences in violent behavior are less pronounced in gender-equalitarian neighborhoods compared to those characterized by gender inequality. We also find that the gender gap narrows in gender-equalitarian neighborhoods because boys' rates of violence decrease whereas girls' rates remain relatively low across neighborhoods. This is in stark contrast to the pessimistic predictions of theorists who argue that the narrowing of the gender gap in equalitarian settings is the result of an increase in girls' violence. In addition, the relationship between neighborhood gender equality and violence is mediated by a specific articulation of masculinity characterized by toughness. Our results provide evidence for the use of gender-specific neighborhood prevention programs. PMID:24672996

  2. Animating Brains.

    PubMed

    Borck, Cornelius

    2016-07-01

    A recent paper famously accused the rising field of social neuroscience of using faulty statistics under the catchy title 'Voodoo Correlations in Social Neuroscience'. This Special Issue invites us to take this claim as the starting point for a cross-cultural analysis: in which meaningful ways can recent research in the burgeoning field of functional imaging be described as, contrasted with, or simply compared to animistic practices? And what light does such a reading shed on the dynamics and effectiveness of a century of brain research into higher mental functions? Reviewing the heated debate from 2009 around recent trends in neuroimaging as a possible candidate for current instances of 'soul catching', the paper will then compare these forms of primarily image-based brain research with older regimes, revolving around the deciphering of the brain's electrical activity. How has the move from a decoding paradigm to a representational regime affected the conceptualisation of self, psyche, mind and soul (if there still is such an entity)? And in what ways does modern technoscience provide new tools for animating brains? PMID:27292322

  3. Smart Brains.

    ERIC Educational Resources Information Center

    Jones, Rebecca

    1995-01-01

    New techniques have opened windows to the brain. Although the biochemistry of learning remains largely a mystery, the following findings seem to have clear implications for education: (1) the importance of early-learning opportunities for the very young; (2) the connection between music and abstract reasoning; and (3) the importance of good…

  4. Vision's Brain.

    ERIC Educational Resources Information Center

    Miller, Julie Ann

    1978-01-01

    The functional architecture of the primary visual cortex has been explored by monitoring the responses of individual brain cells to visual stimuli. A combination of anatomical and physiological techniques reveals groups of functionally related cells, juxtaposed and superimposed, in a sometimes complex, but presumably efficient, structure. (BB)

  5. Digital rights management for digital cinema

    NASA Astrophysics Data System (ADS)

    Kirovski, Darko; Peinado, Marcus; Petitcolas, Fabien A. P.

    2001-12-01

    There is a wide consensus among the feature film production studios that the Internet era brings a new paradigm for film distribution to cinemas worldwide. The benefits of digital cinema to both producers and cinemas are numerous: significantly lower distribution and maintenance costs, immediate access to film libraries, higher presentation quality, and strong potential for developing new business models. Despite these advantages, the studios are still reluctant to jump into the digital age. The main showstopper for digital cinema is the danger of widespread piracy. Piracy already costs Hollywood an estimated two billion dollars annually and digital cinema without proper copyright enforcement could increase this number. In this paper, we present a copyright management system that aims at providing the set of necessary security tools: standard cryptographic primitives and copyright protection mechanisms that enable a reliable and secure feature film delivery system.

  6. Digital Collections, Digital Libraries and the Digitization of Cultural Heritage Information.

    ERIC Educational Resources Information Center

    Lynch, Clifford

    2002-01-01

    Discusses the development of digital collections and digital libraries. Topics include digitization of cultural heritage information; broadband issues; lack of compelling content; training issues; types of materials being digitized; sustainability; digital preservation; infrastructure; digital images; data mining; and future possibilities for…

  7. Is Face Distinctiveness Gender Based?

    ERIC Educational Resources Information Center

    Baudouin, Jean-Yves; Gallay, Mathieu

    2006-01-01

    Two experiments were carried out to study the role of gender category in evaluations of face distinctiveness. In Experiment 1, participants had to evaluate the distinctiveness and the femininity-masculinity of real or artificial composite faces. The composite faces were created by blending either faces of the same gender (sexed composite faces,…

  8. Sex, Gender, Genetics, and Health

    PubMed Central

    Yang, Yang Claire; Jenkins, Tania M.

    2013-01-01

    This article addresses 2 questions. First, to what extent are sex and gender incorporated into research on genetics and health? Second, how might social science understandings of sex and gender, and gender differences in health, become more integrated into scholarship in this area? We review articles on genetics and health published in selected peer-reviewed journals. Although sex is included frequently as a control or stratifying variable, few articles articulate a conceptual frame or methodological justification for conducting research in this way, and most are not motivated by sex or gender differences in health. Gender differences in health are persistent, unexplained, and shaped by multilevel social factors. Future scholarship on genetics and health needs to incorporate more systematic attention to sex and gender, gender as an environment, and the intertwining of social and biological variation over the life course. Such integration will advance understandings of gender differences in health, and may yield insight regarding the processes and circumstances that make genomic variation relevant for health and well-being. PMID:23927517

  9. Gender, Power, and Autobiographical Memory.

    ERIC Educational Resources Information Center

    Nakash-Eisikovits, Ora; Brody, Leslie R.; Sotoo, Naomi; Gonzalez, Karla

    This study explores the influence of gender and power on autobiographical memory following a brief social interaction. The hypothesis stated that gender and social role (that of leaders versus helpers) would interact in predicting the affective tone and themes (agency and communion) of an autobiographical memory for previous leadership…

  10. Why "Gender" Disappeared from the Gender Gap: (Re-)Introducing Gender Identity Theory to Educational Gender Gap Research

    ERIC Educational Resources Information Center

    Vantieghem, Wendelien; Vermeersch, Hans; Van Houtte, Mieke

    2014-01-01

    Educational gender gap research tries to explain the differential achievement of boys and girls at secondary school, which manifests in many western countries. Several explanatory frameworks are used for this purpose, such as masculinities theory. In this review article, the history of educational gender gap research in Anglo-Saxon literature and…

  11. Gender Differences in Cognitive Development

    ERIC Educational Resources Information Center

    Ardila, Alfredo; Rosselli, Monica; Matute, Esmeralda; Inozemtseva, Olga

    2011-01-01

    The potential effect of gender on intellectual abilities remains controversial. The purpose of this research was to analyze gender differences in cognitive test performance among children from continuous age groups. For this purpose, the normative data from 7 domains of the newly developed neuropsychological test battery, the Evaluacion…

  12. Gender Differences in Mathematical Trajectories.

    ERIC Educational Resources Information Center

    Leahey, Erin; Guo, Guang

    2001-01-01

    Large national data sets and curvilinear growth models were used to examine gender differences in mathematics achievement trajectories from elementary through high school. Despite relatively equal starting points and relatively equal slopes, boys had a faster rate of acceleration, resulting in a slight gender difference by 12th grade. (Contains 39…

  13. Diversity: Gender, Color, and Culture.

    ERIC Educational Resources Information Center

    Essed, Philomena

    This book serves as an introduction to issues of diversity. Each chapter addresses an issue relevant to life and work in gender-conscious and ethnically diverse environments. Taken together, the chapters challenge the reader to develop alternative views on gender, color, culture, and human relations. The first chapter introduces key notions, such…

  14. Gender, Education, Extremism and Security

    ERIC Educational Resources Information Center

    Davies, Lynn

    2008-01-01

    This paper examines the complex relationships between gender, education, extremism and security. After defining extremism and fundamentalism, it looks first at the relationship of gender to violence generally, before looking specifically at how this plays out in more extremist violence and terrorism. Religious fundamentalism is also shown to have…

  15. Gender Issues in Language Change.

    ERIC Educational Resources Information Center

    Cameron, Deborah

    2003-01-01

    Drawing on recent work in variationist sociolinguistics, sociology of language and linguistic anthropology, focuses on new approaches to explaining gender differentiated patterns of sound change and language shift, the success or failure of planned linguistic reforms, and changes in the social evaluation of gendered speech styles. (Author/VWL)

  16. Gender Differences in Mathematics Performance.

    ERIC Educational Resources Information Center

    Porter, Rhonda C.

    Since the 1960s, gender differences in mathematics performance have been a major topic in educational and mathematical research. This study entails a gender comparative analysis of students' mathematics performance as determined by the Iowa Test of Basic Skills and by the Tests of Achievement and Proficiency. In a public school system in rural…

  17. Designing Exhibits for Gender Equity

    ERIC Educational Resources Information Center

    Dancu, Toni Nicole

    2010-01-01

    Gender equity has been a national and global aim for over half a century (Ceci & Williams, 2007; National Center for Education Statistics, 2003; National Science Board, 2008). While gains have been made, one area where inequity remains is spatial reasoning ability, where a large gender gap in favor of males has persisted over the years…

  18. Gender Equality in Teacher Organisations.

    ERIC Educational Resources Information Center

    Lund, Torill Scharning

    1995-01-01

    Most senior trade union posts are held by men, even in organizations where most members are women. The paper examines how the Norwegian Union of Teachers has advanced in this area, noting the status of gender equality in Norway, Norway's work toward gender equality, and the country's focus on educational change. (SM)

  19. Gender Issues in Art Education.

    ERIC Educational Resources Information Center

    McCoubrey, Sharon, Ed.

    2000-01-01

    The expectation of educators for more than a decade has been that they would be aware of and attend to gender issues. The British Columbia Visual Arts Curricula states "Gender-equitable education will initially focus on girls in order to redress historical inequities." However, it is important to be informed about the issues that adversely affect…

  20. Children's Perceptions of Gender Discrimination

    ERIC Educational Resources Information Center

    Brown, Christia Spears; Bigler, Rebecca S.

    2004-01-01

    Children (N = 76; ages 5-10 years) participated in a study designed to examine perceptions of gender discrimination. Children were read scenarios in which a teacher determined outcomes for 2 students (1 boy and 1 girl). Contextual information (i.e., teacher's past behavior), the gender of the target of discrimination (i.e., student), and the…

  1. Investigating Gender Differences in Reading

    ERIC Educational Resources Information Center

    Logan, Sarah; Johnston, Rhona

    2010-01-01

    Girls consistently outperform boys on tests of reading comprehension, although the reason for this is not clear. In this review, differences between boys and girls in areas relating to reading will be investigated as possible explanations for consistent gender differences in reading attainment. The review will examine gender differences within the…

  2. Preservice Teacher Talk Surrounding Gender

    ERIC Educational Resources Information Center

    Engebretson, Kathryn Ellerhoff

    2012-01-01

    This dissertation examines the discourses around gender present among a cohort of preservice secondary social studies teachers (n = 25) and how gender discourses manifested throughout their preparatory year with particular interest paid to their thoughts about curricula, schools, and students. Using ethnographic study design, the author presents…

  3. Gender Mainstreaming or Promoting Women?

    ERIC Educational Resources Information Center

    Faulstich-Wieland, Hannelore

    2005-01-01

    Gender inequalities in education are very apparent. Young women are overrepresented in educational training and in the school-based training and correspondingly underrepresented in the dual training courses. Gender segmentation in professional education continues to exist. Women are overrepresented in the service sector, while men are in…

  4. Gender in physics in Denmark

    NASA Astrophysics Data System (ADS)

    Niss, Kristine; Nordström, Birgitta; Bearden, Ian; Grage, Mette M.-L.

    2013-03-01

    More women than men get a college degree in Denmark. However, Denmark still has very gender-separated labor market, and in physics only 10% of the university professors are women. Measures are needed to get a more balanced gender distribution among university physicists at all levels in Denmark.

  5. Gendered Performances during Peer Revision

    ERIC Educational Resources Information Center

    Styslinger, Mary E.

    2008-01-01

    This study explored the ways gender is accomplished in varied social contexts during the peer revision process in a secondary English classroom. Using a post-structural feminist theoretical framework, an analysis of classroom discourse provided a basis for understanding the performance of gender during peer revision, the effects of gender…

  6. Understanding Brain Tumors

    MedlinePlus

    ... to Know About Brain Tumors . What is a Brain Tumor? A brain tumor is an abnormal growth
 ... Tumors” from Frankly Speaking Frankly Speaking About Cancer: Brain Tumors Download the full book Questions to ask ...

  7. Brain Tumors (For Parents)

    MedlinePlus

    ... Story" 5 Things to Know About Zika & Pregnancy Brain Tumors KidsHealth > For Parents > Brain Tumors Print A ... radiation therapy or chemotherapy, or both. Types of Brain Tumors There are many different types of brain ...

  8. Brain tumor - children

    MedlinePlus

    ... children; Neuroglioma - children; Oligodendroglioma - children; Meningioma - children; Cancer - brain tumor (children) ... The cause of primary brain tumors is unknown. Primary brain tumors may ... (spread to nearby areas) Cancerous (malignant) Brain tumors ...

  9. Brain Tumor Diagnosis

    MedlinePlus

    ... Types of Brain Scans X-rays Laboratory Tests DNA Profiling Biopsy Procedure Malignant and Benign Brain Tumors Tumor ... Types of Brain Scans X-rays Laboratory Tests DNA Profiling Biopsy Procedure Malignant and Benign Brain Tumors Tumor ...

  10. Interactive and additive influences of Gender, BMI and Apolipoprotein 4 on cognition in children chronically exposed to high concentrations of PM2.5 and ozone. APOE 4 females are at highest risk in Mexico City.

    PubMed

    Calderón-Garcidueñas, Lilian; Jewells, Valerie; Galaz-Montoya, Carolina; van Zundert, Brigitte; Pérez-Calatayud, Angel; Ascencio-Ferrel, Eric; Valencia-Salazar, Gildardo; Sandoval-Cano, Marcela; Carlos, Esperanza; Solorio, Edelmira; Acuña-Ayala, Hilda; Torres-Jardón, Ricardo; D'Angiulli, Amedeo

    2016-10-01

    Children's air pollution exposures are associated with systemic and brain inflammation and the early hallmarks of Alzheimer's disease (AD). The Apolipoprotein E (APOE) 4 allele is the most prevalent genetic risk for AD, with higher risk for women. We assessed whether gender, BMI, APOE and metabolic variables in healthy children with high exposures to ozone and fine particulate matter (PM2.5) influence cognition. The Wechsler Intelligence Scale for Children (WISC-R) was administered to 105 Mexico City children (12.32±5.4 years, 69 APOE 3/3 and 36 APOE 3/4). APOE 4v 3 children showed decrements on attention and short-term memory subscales, and below-average scores in Verbal, Performance and Full Scale IQ. APOE 4 females had higher BMI and females with normal BMI between 75-94% percentiles had the highest deficits in Total IQ, Performance IQ, Digit Span, Picture Arrangement, Block Design and Object Assembly. Fasting glucose was significantly higher in APOE 4 children p=0.006, while Gender was the main variable accounting for the difference in insulin, HOMA-IR and leptin (p<.05). Gender, BMI and APOE influence children's cognitive responses to air pollution and glucose is likely a key player. APOE 4 heterozygous females with >75% to <94% BMI percentiles are at the highest risk of severe cognitive deficits (1.5-2SD from average IQ). Young female results highlight the urgent need for gender-targeted health programmes to improve cognitive responses. Multidisciplinary intervention strategies could provide paths for prevention or amelioration of female air pollution targeted cognitive deficits and possible long-term AD progression. PMID:27376929

  11. Threatened by Gender?

    NASA Astrophysics Data System (ADS)

    Humpherys, Candice; Pyper, Brian

    2006-10-01

    A good deal of research has been done on the issue of stereotype threat.^1, 2 This research proposes that if a person identifies with a group of people that is negatively stereotyped for performance, then they will not perform as well as someone from the same group of people who is not made aware of the negative stereotype. The research we conducted investigates the legitimacy of stereotype threat based on gender in the area of science in the BYU-Idaho student population. Our results have significance in the current national debate about the lack of women pursuing careers in scientific disciplines. ^1 Quinn, Diane M.; Spencer, Steven J.. (2001). The Interference of Stereotype Threat With Women's Generation of Mathematical Problem-Solving Strategies. Journal of Social Issues. 57(1):55-71. ^2 Schmader, Tony, & Johns, Michael. (2003). Converging Evidence That Stereotype Threat Reduces Working Memory Capacity. Journal of Personality and Social Psychology. 85(3):440-452.

  12. Threatened Because of Gender?

    NASA Astrophysics Data System (ADS)

    Humpherys, Candice; Pyper, Brian

    2006-05-01

    A good deal of research has been done on the issue of stereotype threat. [1, 2] This research proposes that if a person identifies with a group of people that is negatively stereotyped for performance, then they will not perform as well as someone from the same group of people who is not made aware of the negative stereotype. The research we conducted investigates the legitimacy of stereotype threat based on gender in the area of science in the BYU-Idaho student population. Our results have significance in the current national debate about the lack of women pursuing careers in scientific disciplines. [1] Quinn, Diane M.; Spencer, Steven J.. (2001). The Interference of Stereotype Threat With Women's Generation of Mathematical Problem-Solving Strategies. Journal of Social Issues. 57(1):55-71. [2] Schmader, Tony, & Johns, Michael. (2003). Converging Evidence That Stereotype Threat Reduces Working Memory Capacity. Journal of Personality and Social Psychology. 85(3):440-452.

  13. [Laughter: gender differences].

    PubMed

    Mora-Ripoll, R; Ubal-López, R

    2011-01-01

    Laughter is associated to many physiological and psychological benefits. Although women laugh more than men do, the daily frequency of laughter does not seem to differ. Laughter in all its forms and manifestations is an indicator of family vitality and healthy couples. Laughter is very attractive at the interpersonal level, especially for women. Men use humor much more and laughter when it comes to discussing sensitive health issues. In women, laughter would be more associated with greater social support in relationships and as a tool to cope with stress. Inviting laughter in the doctor's office may be very useful when directing certain messages on therapeutic management. Taking into account possible gender differences in the use of humor and laughter may help to improve the relationship with the patient and optimize the clinical application of laughter in health care and education setting. PMID:21489520

  14. Geography and gender.

    PubMed

    Bondi, L

    1989-05-01

    Most people in Britain today work in jobs dominated very markedly by either women or men. Sex-typing occurs in many other activities. For example, child care and domestic work, whether paid or unpaid, are generally considered to be tasks for women. However, with the exception of domestic work and child care, the allocation of activities to women or men varies between societies. For example, in much of sub-Saharan Africa, women work in fields, growing basic subsistence crops for their families, whereas in much of Latin America, women's agricultural work is confined to tending animals and food processing. Inequality arises because the role of women is generally associated with inferior status, socially, politically and/or economically. When mapping the geography of gender, an example shows that female life expectancy at birth is highest in the developed countries and lowest in the poorest countries of the Third World. Regarding the relationship between gender divisions and various aspects of spatial organization within societies most attention has focused on differences in ethnic group, social class, and stage in the life cycle. In mid-19th century Britain large-scale factory production precipitated a spatial separation between home and work and created the possibility of separate spheres of life for women and men. A particular social form, namely a nuclear family with a dependent wife, can operate as a factor contributing to changes in the spatial organization of urban areas in the form of suburban growth. After decades of outward movement by affluent social groups, a return to small pockets within inner-urban areas is now evident. This process is known as gentrification. An additional factor of significance in connection with gentrification is the increasing success of middle-class women in obtaining well-paid career jobs. PMID:12320248

  15. The Popular Profile of the Digital Learner: Technology Use Patterns and Approaches to Learning

    ERIC Educational Resources Information Center

    Thompson, Penny Marie

    2012-01-01

    The purpose of this study was to investigate the claims made in the popular press about the "digital native" generation as learners. Because students' lives today are saturated with digital media at a time when their brains are still developing, many popular press authors claim that this generation of students thinks and learns…

  16. iGeneration: The Social Cognitive Effects of Digital Technology on Teenagers

    ERIC Educational Resources Information Center

    Ives, Eugenia A.

    2012-01-01

    The purpose of this study was to examine and better understand the social cognitive effects of digital technology on teenagers' brains and their socialization processes, as well as to learn best practices with regard to digital technology consumption. An extensive literature review was conducted on the social cognitive effects of digital…

  17. The Digital Natives as Learners: Technology Use Patterns and Approaches to Learning

    ERIC Educational Resources Information Center

    Thompson, Penny

    2013-01-01

    This study investigated the claims made in the popular press about the "digital native" generation as learners. Because students' lives today are saturated with digital media at a time when their brains are still developing, many popular press authors claim that this generation of students thinks and learns differently than any generation that has…

  18. Gender Affects Semantic Competition: The Effect of Gender in a Non-Gender-Marking Language

    ERIC Educational Resources Information Center

    Fukumura, Kumiko; Hyönä, Jukka; Scholfield, Merete

    2013-01-01

    English speakers tend to produce fewer pronouns when a referential competitor has the same gender as the referent than otherwise. Traditionally, this gender congruence effect has been explained in terms of ambiguity avoidance (e.g., Arnold, Eisenband, Brown-Schmidt, & Trueswell, 2000; Fukumura, Van Gompel, & Pickering, 2010). However, an…

  19. Gender Differences in Family Stories: Moderating Influence of Parent Gender Role and Child Gender.

    ERIC Educational Resources Information Center

    Fiese, Barbara H.; Skillman, Gemma

    2000-01-01

    Examined thematic differences in family stories told by parents according to parent and child gender, noting differences according to parent gender-type and matches between story themes and personal values related to child behavior. No significant main effects or interactions for affiliation themes existed. Interaction existed between parent…

  20. Digital work-flow

    PubMed Central

    MARSANGO, V.; BOLLERO, R.; D’OVIDIO, N.; MIRANDA, M.; BOLLERO, P.; BARLATTANI, A.

    2014-01-01

    SUMMARY Objective. The project presents a clinical case in which the digital work-flow procedure was applied for a prosthetic rehabilitation in natural teeth and implants. Materials. Digital work-flow uses patient’s photo for the aesthetic’s planning, digital smile technology for the simulation of the final restoration and real time scanning to register the two arches. Than the scanning are sent to the laboratory that proceed with CAD-CAM production. Results. Digital work-flow offers the opportunities to easily speak with laboratory and patients, gives better clinical results and demonstrated to be a less invasiveness method for the patient. Conclusion. Intra-oral scanner, digital smile design, preview using digital wax-up, CAD-CAM production, are new predictable opportunities for prosthetic team. This work-flow, compared with traditional methods, is faster, more precise and predictable. PMID:25694797

  1. Digital radiography: an overview.

    PubMed

    Parks, Edwin T; Williamson, Gail F

    2002-11-15

    Since the discovery of X-rays in 1895, film has been the primary medium for capturing, displaying, and storing radiographic images. It is a technology that dental practitioners are the most familiar and comfortable with in terms of technique and interpretation. Digital radiography is the latest advancement in dental imaging and is slowly being adopted by the dental profession. Digital imaging incorporates computer technology in the capture, display, enhancement, and storage of direct radiographic images. Digital imaging offers some distinct advantages over film, but like any emerging technology, it presents new and different challenges for the practitioner to overcome. This article presents an overview of digital imaging including basic terminology and comparisons with film-based imaging. The principles of direct and indirect digital imaging modalities, intraoral and extraoral applications, image processing, and diagnostic efficacy will be discussed. In addition, the article will provide a list of questions dentists should consider prior to purchasing digital imaging systems for their practice. PMID:12444400

  2. Sexuality and Gender Role in Autism Spectrum Disorder: A Case Control Study

    PubMed Central

    Bejerot, Susanne; Eriksson, Jonna M.

    2014-01-01

    The ‘extreme male brain theory of autism’ describes an extreme male pattern of cognitive traits defined as strong systemising abilities paired with empathising weaknesses in autism spectrum disorder. However, beyond these cognitive traits, clinical observations have suggested an ambiguous gender-typed pattern regarding several sexually dimorphic traits. The aim of the present study was to investigate if patterns of non-cognitive sexually dimorphic traits differed between the autism spectrum disorder and control groups. Fifty adults with autism spectrum disorder and intelligence within the normal range, and 53 neurotypical controls responded to questions on gender role, self-perceived gender typicality and gender identity, as well as sexuality. Measures used were a Swedish modification of the Bem Sex Role Inventory and questions on sexuality and gender designed for the purpose of this study. Our results showed that one common gender role emerged in the autism spectrum disorder group. Masculinity (e.g. assertiveness, leadership and competitiveness) was weaker in the autism spectrum disorder group than in the controls, across men and women. Self-perceived gender typicality did not differ between the groups but tomboyism and bisexuality were overrepresented amongst women with autism spectrum disorder. Lower libido was reported amongst both male and female participants with autism spectrum disorder compared with controls. We conclude that the extreme male patterns of cognitive functions in the autistic brain do not seem to extend to gender role and sexuality. A gender-atypical pattern for these types of characteristics is suggested in autism spectrum disorder. PMID:24498228

  3. Martian 'Brain'

    NASA Technical Reports Server (NTRS)

    2004-01-01

    5 May 2004 Most middle-latitude craters on Mars have strange landforms on their floors. Often, the floors have pitted and convoluted features that lack simple explanation. In this case, the central part of the crater floor shown in this 2004 Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) image bears some resemblance to the folded nature of a brain. Or not. It depends upon the 'eye of the beholder,' perhaps. The light-toned 'ring' around the 'brain' feature is more easily explained--windblown ripples and dunes. The crater occurs near 33.1oS, 91.2oW, and is illuminated from the upper left. The picture covers an area about 3 km (1.9 mi) across.

  4. Effects of Single-Gender Middle School Classes on Science Achievement and Attitude

    NASA Astrophysics Data System (ADS)

    Brooks, Tanisha

    Many girls continue to achieve below their male counterparts and portray negative attitudes towards science classes. Some school districts are using single-gender education as a way to shrink the gender gap in school achievement and science related attitude. The purpose of this study was to compare achievement and science-related attitudes of 7th grade girls in single-gender education to 7th grade girls in mixed-gender education. The theoretical base for this study included knowledge from brain-based learning and assimilation, accommodation and age factors of Piaget's theory of cognitive development. The 12-week study included 48 7th grade girls, 21 in the single-gender classroom and 14 in each mixed-gender classroom. This quantitative randomized posttest only control group design utilized the TerraNova Science Assessment and the Test of Science Related Attitudes. Analysis of Variance (ANOVA) was used to determine if significant differences existed in the achievement and attitudes of girls in single and mixed-gender science classes. ANOVA analyses revealed that the girls in the single-gender classroom showed a significantly higher achievement level when compared to girls in the mixed-gender classrooms. Results showed no significant difference in attitude between the two groups. The results of this study contribute to social change by raising awareness about gender issues in science achievement and attitude, addressing a deficiency in the single-gender science education literature, and assisting educational systems in decision making to address achievement gaps while moving toward adequate yearly progress and meeting the requirements of the No Child Left Behind Act of 2001.

  5. Brain imaging

    SciTech Connect

    Bradshaw, J.R.

    1989-01-01

    This book presents a survey of the various imaging tools with examples of the different diseases shown best with each modality. It includes 100 case presentations covering the gamut of brain diseases. These examples are grouped according to the clinical presentation of the patient: headache, acute headache, sudden unilateral weakness, unilateral weakness of gradual onset, speech disorders, seizures, pituitary and parasellar lesions, sensory disorders, posterior fossa and cranial nerve disorders, dementia, and congenital lesions.

  6. Digital Sensor Technology

    SciTech Connect

    Thomas, Ken D.; Quinn, Edward L.; Mauck, Jerry L.; Bockhorst, Richard M.

    2015-02-01

    The nuclear industry has been slow to incorporate digital sensor technology into nuclear plant designs due to concerns with digital qualification issues. However, the benefits of digital sensor technology for nuclear plant instrumentation are substantial in terms of accuracy and reliability. This paper, which refers to a final report issued in 2013, demonstrates these benefits in direct comparisons of digital and analog sensor applications. Improved accuracy results from the superior operating characteristics of digital sensors. These include improvements in sensor accuracy and drift and other related parameters which reduce total loop uncertainty and thereby increase safety and operating margins. An example instrument loop uncertainty calculation for a pressure sensor application is presented to illustrate these improvements. This is a side-by-side comparison of the instrument loop uncertainty for both an analog and a digital sensor in the same pressure measurement application. Similarly, improved sensor reliability is illustrated with a sample calculation for determining the probability of failure on demand, an industry standard reliability measure. This looks at equivalent analog and digital temperature sensors to draw the comparison. The results confirm substantial reliability improvement with the digital sensor, due in large part to ability to continuously monitor the health of a digital sensor such that problems can be immediately identified and corrected. This greatly reduces the likelihood of a latent failure condition of the sensor at the time of a design basis event. Notwithstanding the benefits of digital sensors, there are certain qualification issues that are inherent with digital technology and these are described in the report. One major qualification impediment for digital sensor implementation is software common cause failure (SCCF).

  7. Digital Longitudinal Tomosynthesis

    NASA Astrophysics Data System (ADS)

    Rimkus, Daniel Steven

    1985-12-01

    The purpose of this dissertation was to investigate the clinical utility of digital longitudinal tomosynthesis in radiology. By acquiring a finite group of digital images during a longitudinal tomographic exposure, and processing these images, tomographic planes, other than the fulcrum plane, can be reconstructed. This process is now termed "tomosynthesis". A prototype system utilizing this technique was developed. Both phantom and patient studies were done with this system. The phantom studies were evaluated by subjective, visual criterion and by quantitative analysis of edge sharpness and noise in the reconstructions. Two groups of patients and one volunteer were studied. The first patient group consisted of 8 patients undergoing intravenous urography (IVU). These patients had digital tomography and film tomography of the abdomen. The second patient group consisted of 4 patients with lung cancer admitted to the hospital for laser resection of endobronchial tumor. These patients had mediastinal digital tomograms to evaluate the trachea and mainstem bronchi. The knee of one volunteer was imaged by film tomography and digital tomography. The results of the phantom studies showed that the digital reconstructions accurately produced images of the desired planes. The edge sharpness of the reconstructions approached that of the acquired images. Adequate reconstructions were achieved with as few as 5 images acquired during the exposure, with the quality of the reconstructions improving as the number of images acquired increased. The IVU patients' digital studies had less contrast and spatial resolution than the film tomograms. The single renal lesion visible on the film tomograms was also visible in the digital images. The digital mediastinal studies were felt by several radiologists to be superior to a standard chest xray in evaluating the airways. The digital images of the volunteer's knee showed many of the same anatomic features as the film tomogram, but the digital

  8. The Electrophysiological Underpinnings of Processing Gender Stereotypes in Language

    PubMed Central

    Siyanova-Chanturia, Anna; Pesciarelli, Francesca; Cacciari, Cristina

    2012-01-01

    Despite the widely documented influence of gender stereotypes on social behaviour, little is known about the electrophysiological substrates engaged in the processing of such information when conveyed by language. Using event-related brain potentials (ERPs), we examined the brain response to third-person pronouns (lei “she” and lui “he”) that were implicitly primed by definitional (passeggeraFEM “passenger”, pensionatoMASC “pensioner”), or stereotypical antecedents (insegnante “teacher”, conducente “driver”). An N400-like effect on the pronoun emerged when it was preceded by a definitionally incongruent prime (passeggeraFEM – lui; pensionatoMASC – lei), and a stereotypically incongruent prime for masculine pronouns only (insegnante – lui). In addition, a P300-like effect was found when the pronoun was preceded by definitionally incongruent primes. However, this effect was observed for female, but not male participants. Overall, these results provide further evidence for on-line effects of stereotypical gender in language comprehension. Importantly, our results also suggest a gender stereotype asymmetry in that male and female stereotypes affected the processing of pronouns differently. PMID:23226494

  9. Digital In, Digital Out: Digital Editing with Firewire.

    ERIC Educational Resources Information Center

    Doyle, Bob; Sauer, Jeff

    1997-01-01

    Reviews linear and nonlinear digital video (DV) editing equipment and software, using the IEEE 1394 (FireWire) connector. Includes a chart listing specifications and rating eight DV editing systems, reviews two DV still-photo cameras, and previews beta DV products. (PEN)

  10. Debunking the "Digital Native": Beyond Digital Apartheid, towards Digital Democracy

    ERIC Educational Resources Information Center

    Brown, C.; Czerniewicz, L.

    2010-01-01

    This paper interrogates the currently pervasive discourse of the "net generation" finding the concept of the "digital native" especially problematic, both empirically and conceptually. We draw on a research project of South African higher education students' access to and use of Information and Communication Technologies (ICTs) to show that age is…

  11. Animating Brains

    PubMed Central

    Borck, Cornelius

    2016-01-01

    A recent paper famously accused the rising field of social neuroscience of using faulty statistics under the catchy title ‘Voodoo Correlations in Social Neuroscience’. This Special Issue invites us to take this claim as the starting point for a cross-cultural analysis: in which meaningful ways can recent research in the burgeoning field of functional imaging be described as, contrasted with, or simply compared to animistic practices? And what light does such a reading shed on the dynamics and effectiveness of a century of brain research into higher mental functions? Reviewing the heated debate from 2009 around recent trends in neuroimaging as a possible candidate for current instances of ‘soul catching’, the paper will then compare these forms of primarily image-based brain research with older regimes, revolving around the deciphering of the brain’s electrical activity. How has the move from a decoding paradigm to a representational regime affected the conceptualisation of self, psyche, mind and soul (if there still is such an entity)? And in what ways does modern technoscience provide new tools for animating brains? PMID:27292322

  12. Digital security technology simplified.

    PubMed

    Scaglione, Bernard J

    2007-01-01

    Digital security technology is making great strides in replacing analog and other traditional security systems including CCTV card access, personal identification and alarm monitoring applications. Like any new technology, the author says, it is important to understand its benefits and limitations before purchasing and installing, to ensure its proper operation and effectiveness. This article is a primer for security directors on how digital technology works. It provides an understanding of the key components which make up the foundation for digital security systems, focusing on three key aspects of the digital security world: the security network, IP cameras and IP recorders. PMID:17907609

  13. Digital solar system geology

    NASA Technical Reports Server (NTRS)

    Batson, R. M.; Kozak, R. C.; Isbell, Nancy K.

    1991-01-01

    All available synoptic maps of the solid-surface bodies of the Solar System were digitized for presentation in the planned Atlas of the Solar System by Greeley and Batson. Since the last report (Batson et al., 1990), preliminary Uranian satellite maps were replaced with improved versions, Galilean satellite geology was simplified and digitized, structure was added to many maps, and the maps were converted to a standard format, with corresponding standing colors for the mapped units. Following these changes, the maps were re-reviewed by their authors and are now undergoing final editing before preparation for publication. In some cases (for Mercury, Venus, and Mars), more detailed maps were digitized and then simplified for the Atlas. Other detailed maps are planned to be digitized in the coming year for the Moon and the Galilean satellites. For most of the remaining bodies such as the Uranian satellites, the current digitized versions contain virtually all the detail that can be mapped given the available data; those versions will be unchanged for the Atlas. These digital geologic maps are archived at the digital scale of 1/16 degree/ pixel, in sinusoidal format. The availability of geology of the Solar System in a digital database will facilitate comparisons and integration with other data: digitized lunar geologic maps have already been used in a comparison with Galileo SSI observations of the Moon.

  14. Experiments in digital literacy.

    PubMed

    Eshet-Alkali, Yoram; Amichai-Hamburger, Yair

    2004-08-01

    Having digital literacy requires more than just the ability to use software or to operate a digital device; it includes a large variety of complex skills such as cognitive, motoric, sociological, and emotional that users need to have in order to use digital environments effectively. A conceptual model that was recently described by the authors suggests that digital literacy comprises five major digital skills: photo-visual skills ("reading" instructions from graphical displays), reproduction skills (utilizing digital reproduction to create new, meaningful materials from preexisting ones), branching skills (constructing knowledge from non-linear, hypertextual navigation), information skills (evaluating the quality and validity of information), and socio-emotional skills (understanding the "rules" that prevail in cyberspace and applying this understanding in online cyberspace communication). The present paper presents results from a performance-based pioneer study that investigated the application of the above digital literacy skills conceptual model among different groups of scholars. Results clearly indicate that the younger participants performed better than the older ones, with photo-visual and branching literacy tasks, whereas the older participants were found to be more literate in reproduction and information literacy tasks. Research results shed light on the cognitive skills that users utilize in performing with digital environments, and provide educators and software developers with helpful guidelines for designing better user-centered digital environments. PMID:15331029

  15. Digitization Best Practices

    SciTech Connect

    Xue, Fei; Holtkamp, Irma S.; Knudson, Frances L.

    2012-07-31

    This project involved performing tests and documenting results to determine best practices for digitizing older print documents. The digitization process is complicated, especially when original documents exhibit non-standard fonts and are faded. Tests focused on solutions to improve high quality scanning, increase OCR accuracy, and efficiently use embedded metadata. Results are summarized. From the test results on the right sides, we know that when we plan to digitize documents, we should balance Quantity and Quality based on our expectation, and then make final decision for the digitization process.

  16. Exploring digital professionalism.

    PubMed

    Ellaway, Rachel H; Coral, Janet; Topps, David; Topps, Maureen

    2015-01-01

    The widespread use of digital media (both computing devices and the services they access) has blurred the boundaries between our personal and professional lives. Contemporary students are the last to remember a time before the widespread use of the Internet and they will be the first to practice in a largely e-health environment. This article explores concepts of digital professionalism and their place in contemporary medical education, and proposes a series of principles of digital professionalism to guide teaching, learning and practice in the healthcare professions. Despite the many risks and fears surrounding their use, digital media are not an intrinsic threat to medical professionalism. Professionals should maintain the capacity for deliberate, ethical, and accountable practice when using digital media. The authors describe a digital professionalism framework structured around concepts of proficiency, reputation, and responsibility. Digital professionalism can be integrated into medical education using strategies based on awareness, alignment, assessment, and accountability. These principles of digital professionalism provide a way for medical students and medical practitioners to embrace the positive aspects of digital media use while being mindful and deliberate in its use to avoid or minimize any negative consequences. PMID:26030375

  17. Differences in Information Mapping Strategies in Left and Right Brain Learners.

    ERIC Educational Resources Information Center

    Hauck, LaVerne S., Jr.

    The Information Mapping technique was used to present a learning packet, and its usefulness in helping right-brain cerebrally dominant students to achieve the same level of subject mastery as their left-brain counterparts was examined. Reading level, grade point average, and gender were also analyzed. Torrance's "Your Style of Learning and…

  18. Implications of Brain Research for Teaching Young Adolescents. What Research Says.

    ERIC Educational Resources Information Center

    Wilson, Lucinda M.; Horch, Hadley Wilson

    2002-01-01

    Summarizes research findings related to brain maturation during the adolescent years and highlights implications for the middle level educator, focusing on the types of classroom activities most compatible with attention and memory. Examines possible gender differences in how adolescents learn, the effects of stress on the brain, and implications…

  19. Sex Differences in Brain Activity Related to General and Emotional Intelligence

    ERIC Educational Resources Information Center

    Jausovec, Norbert; Jausovec, Ksenija

    2005-01-01

    The study investigated gender differences in resting EEG (in three individually determined narrow [alpha] frequency bands) related to the level of general and emotional intelligence. Brain activity of males decreased with the level of general intelligence, whereas an opposite pattern of brain activity was observed in females. This difference was…

  20. Syrians' Acceptance of Digital Lectures: A Case Study

    ERIC Educational Resources Information Center

    Ramadan, Reem

    2016-01-01

    Technology-based learning modules are mostly challenged by their acceptance. A single-case study and mixed research method are used to explore a unique situation of applying digital lectures at the postgraduate Programmes at the Faculty of Tourism at Damascus University as a solution for brain drain in the Syrian higher education system. Results…

  1. Statistical analysis of brain sulci based on active ribbon modeling

    NASA Astrophysics Data System (ADS)

    Barillot, Christian; Le Goualher, Georges; Hellier, Pierre; Gibaud, Bernard

    1999-05-01

    This paper presents a general statistical framework for modeling deformable object. This model is devoted being used in digital brain atlases. We first present a numerical modeling of brain sulci. We present also a method to characterize the high inter-individual variability of basic cortical structures on which the description of the cerebral cortex is based. The aimed applications use numerical modeling of brain sulci to assist non-linear registration of human brains by inter-individual anatomical matching or to better compare neuro-functional recordings performed on a series of individuals. The utilization of these methods is illustrated using a few examples.

  2. Comparison of PASS Assessment Scores in Single-Gender and Heterogeneous Middle Schools in South Carolina

    ERIC Educational Resources Information Center

    Canada, Patricia Oxendine

    2012-01-01

    In response to the mandates of No Child Left Behind, (NCLB), educators across the country struggle to close the gaps between males and females. Some of the physiological differences existing between the male and female brain suggest support for single-gender instruction, which is on the rise within this country as well as other parts of the world.…

  3. Effects of Gender-Based Instruction on Fifth Graders' Attitudes toward Mathematics

    ERIC Educational Resources Information Center

    Oswald, Deborah R.

    2009-01-01

    Differences in male and female brains may impact the way girls and boys process mathematics and underscores the need for research that examines modification of mathematics instruction according to gender differences. Based in constructivist theory, this mixed-methods study investigated the effect of mathematics instruction modified according to…

  4. The recognition of gender-marked nouns and verbs in Polish-speaking aphasic patients.

    PubMed

    Perlak, Danuta; Jarema, Gonia

    2003-06-01

    In the present study, we investigated the on-line recognition of gender-marked lexical items by three aphasic patients and eighteen matched control participants, all native speakers of Polish. Polish is unique in that it allows investigating grammatical gender across the major categories of nouns and verbs. Patients and their controls were tested using a simple visual lexical decision paradigm in which gender, number and grammatical category were manipulated. Results show that, while response latencies were markedly slower for aphasic patients, gender did not yield differential results in either grammatical category, for both patients and control participants. Plural forms, on the other hand, showed significantly slower response latencies than singular forms in both brain-damaged and unimpaired participants, but only for nouns. We interpret these findings in terms of the inherent vs. contextual, i.e. underspecified, nature of gender and number in the two grammatical categories. This study suggests that while gender can be impaired in off-line performance in aphasia, on-line recognition patterns parallel the performance of non-brain-damaged individuals, confirming the preservation of access procedures in automatic word recognition. PMID:12870818

  5. The Children Should Lead Us: Diane Ehrensaft's "Gender Born, Gender Made--Raising Healthy Gender-Nonconforming Children"

    ERIC Educational Resources Information Center

    Beemyn, Genny

    2013-01-01

    This article reviews Diane Ehrensaft's "Gender Born, Gender Made: Raising Healthy Gender-Nonconforming Children", a thoughtful and practical guide that can help parents, other family members, and therapists better understand and support children and youth whom the author refers to as "gender creative." Ehrensaft's work is at the forefront of a…

  6. Human Motor Cortex Functional Changes in Acute Stroke: Gender Effects

    PubMed Central

    Di Lazzaro, Vincenzo; Pellegrino, Giovanni; Di Pino, Giovanni; Ranieri, Federico; Lotti, Fiorenza; Florio, Lucia; Capone, Fioravante

    2016-01-01

    The acute phase of stroke is accompanied by functional changes in the activity and interplay of both hemispheres. In healthy subjects, gender is known to impact the functional brain organization. We investigated whether gender influences also acute stroke functional changes. In thirty-five ischemic stroke patients, we evaluated the excitability of the affected (AH) and unaffected hemisphere (UH) by measuring resting and active motor threshold (AMT) and motor-evoked potential amplitude under baseline conditions and after intermittent theta burst stimulation (iTBS) of AH. We also computed an index of the excitability balance between the hemispheres, laterality indexes (LI), to evidence hemispheric asymmetry. AMT differed significantly between AH and UH only in the male group (p = 0.004), not in females (p > 0.200), and both LIAMT and LIRMT were significantly higher in males than in females (respectively p = 0.033 and p = 0.042). LTP-like activity induced by iTBS in AH was more frequent in females. Gender influences the functional excitability changes that take place after human stroke and the level of LTP that can be induced by repetitive stimulation. This knowledge is of high value in the attempt of individualizing to different genders any non-invasive stimulation strategy designed to foster stroke recovery. PMID:26858590

  7. Gender-related behavior in women exposed prenatally to diethylstilbestrol.

    PubMed Central

    Newbold, R R

    1993-01-01

    Accumulating evidence in experimental animals over the past three decades suggests that mammalian brain development and differentiation of the central nervous system are influenced by perinatal exposure to sex hormones. Hence, changes in human behavioral patterns may be associated with prenatal exposure to estrogenic substances such as diethylstilbestrol (DES). This paper reviews relevant studies from a series of laboratories and finds that no clear-cut differences can be demonstrated to date between unexposed and DES-exposed women in gender-related behavior, although the physical and psychological impact of the problems associated with exposure to DES are well documented. If both prenatal and postnatal influences such as social, economic, and environmental factors are taken into consideration, individual variation is more apparent than differences in gender-related behavior between unexposed and DES-exposed women. In summary, gender-related behavior is determined by a complex array of interacting factors, and prenatal influences are only one of many developmental events. More studies are needed using larger populations with carefully controlled selection criteria to suggest a direct role of prenatal DES exposure on subsequent gender-related behavior. Images p208-a PMID:8404755

  8. Digital rights language support for evolving digital cinema requirements

    NASA Astrophysics Data System (ADS)

    Orri, Xavier; Mas, Joan-Maria; Macq, Benoit M. M.

    2003-06-01

    Digital cinema can be defined as the digital electronic distribution and display of theatrical film content or live material to the theatre. However, this simple definition does not reflect the complex mesh of balanced business relationships between the different parties involved in the worldwide cinematic distribution. Its transition from an analogue to a digital business will happen progressively, starting with only content being digitally distributed and going until an all-digital business. From these facts derive strong requirements on digital rights management (DRM) systems for digital cinema and therefore on the digital rights language supporting it. This paper explores the requirements imposed by the cinematic distribution model and by its progressive transition to digital, and the impact these have on digital rights languages. We analyze the support provided by different digital rights languages, identifying weaknesses and exploring solutions in fulfilling the requirements of the digital cinema distribution model.

  9. Sex differences in the brain-an interplay of sex steroid hormones and sex chromosomes.

    PubMed

    Grgurevic, Neza; Majdic, Gregor

    2016-09-01

    Although considerable progress has been made in our understanding of brain function, many questions remain unanswered. The ultimate goal of studying the brain is to understand the connection between brain structure and function and behavioural outcomes. Since sex differences in brain morphology were first observed, subsequent studies suggest different functional organization of the male and female brains in humans. Sex and gender have been identified as being a significant factor in understanding human physiology, health and disease, and the biological differences between the sexes is not limited to the gonads and secondary sexual characteristics, but also affects the structure and, more crucially, the function of the brain and other organs. Significant variability in brain structures between individuals, in addition to between the sexes, is factor that complicates the study of sex differences in the brain. In this review, we explore the current understanding of sex differences in the brain, mostly focusing on preclinical animal studies. PMID:27433022

  10. Predictors of Neuropsychological Test Performance After Pediatric Traumatic Brain Injury

    ERIC Educational Resources Information Center

    Donders, Jacobus; Nesbit-Greene, Kelly

    2004-01-01

    The influence of neurological and demographic variables on neuropsychological test performance was examined in 100 9- to 16-year-old children with traumatic brain injury (TBI). Regression analyses were conducted to determine the relative contributions of coma, neuroimaging findings, ethnicity, socioeconomic status, and gender to variance in…

  11. Naughty or Nice?: Equity, Gender and Behavior

    ERIC Educational Resources Information Center

    Koch, Pamela Ray; Steelman, Lala Carr; Mulkey, Lynn; Catsambis, Sophia

    2008-01-01

    We review the debate over behavior, gender and classroom placement in ability groups for kindergartners. Using vignettes we vary children's gender in three ways; male, female, or unspecified gender and also describe them as behaving well, average, or misbehaving. Our aim is to probe how much gender and behavior matter with respect to mock reading…

  12. Addressing Gender Differences in Young Adolescents.

    ERIC Educational Resources Information Center

    Butler, Deborah A.; Manning, M. Lee

    The current interest in identifying gender differences in young adolescents suggests a need to focus on how gender differences affect teaching and learning situations and on how middle level school educators can address these differences. This book explains what gender differences are, how gender differences affect learning, how both girls and…

  13. Gender Role Socialization in Jewish Men.

    ERIC Educational Resources Information Center

    Lasser, Jon; Gottlieb, Michael C.

    There has been little empirical research on the gender role socialization of Jewish men. This paper explores Jewish male gender role socialization and provides a model by which gender and ethnicity may be studied. A description of the gender role socialization of Jewish men, with an emphasis on advantages and disadvantages of such socialization…

  14. Gender and Close Relationships: An Introduction.

    ERIC Educational Resources Information Center

    Winstead, Barbara A.; Derlega, Valerian J.

    1993-01-01

    Provides a brief summarization of 12 articles focusing on how gender, gender role identity, and attitudes toward gender roles may affect the nature of relationships, and how relationships may affect an individual's gender (including behaviors, attitudes, and self-perceptions). Although the focus is mainly on heterosexual relationships, lesbian/gay…

  15. Computers, Gender Bias, and Young Children.

    ERIC Educational Resources Information Center

    Bhargava, Ambika; Kirova-Petrova, Anna; McNair, Shannan

    1999-01-01

    Discusses gender discrepancy in classroom computer access and use; suggests strategies to minimize gender biases. Argues that gender differences in computer usage are due to biased classroom practices, lack of female role models, home computer gender gaps, and scarcity of bias-free software. Maintains that increased teacher/parent awareness,…

  16. Gender-based Learning Dilemmas in Organizations.

    ERIC Educational Resources Information Center

    Abrahamsson, Lena

    2001-01-01

    A study of eight Swedish companies that reverted to previous forms of work organization shows how gender influences organizational change. The learning organization concept challenges gender order, but gender segregation and stereotypic gender-coding of work are strong mechanisms for reversing change and obstructing individual and organizational…

  17. Closing the Gender Gap: Act Now

    ERIC Educational Resources Information Center

    OECD Publishing (NJ3), 2012

    2012-01-01

    Gender gaps are pervasive in all walks of economic life and imply large losses in terms of foregone productivity and living standards to the individuals concerned and the economy. This new OECD report focuses on how best to close these gender gaps under four broad headings: (1) Gender equality, social norms and public policies; and gender equality…

  18. Gender Equity for Males. WEEA Digest.

    ERIC Educational Resources Information Center

    Flood, Craig, Ed.; Bates, Percy, Ed.; Potter, Julia, Ed.

    Traditionally, the term "gender equity" is associated with equalizing the playing field for girls. However, gender equity by definition applies to both genders. This digest states that, in the best possible scenario, gender equitable education provides equal opportunities and enables each student to reach his or her potential, reducing the gender…

  19. Sex and Gender in Natural Language.

    ERIC Educational Resources Information Center

    Percival, W. Keith

    The relation between a real-world category (sex) and a linguistic category (gender) is examined. The gender system of Indo-European languages is discussed, and the way gender works in Greek, one of the older Indo-European languages, is examined at some length. The conclusion is that, but for the existence of separate gender-sensitive adjectival…

  20. Adolescent and Pediatric Brain Tumors

    MedlinePlus

    ... abta.org Donate Now Menu Adolescent & Pediatric Brain Tumors Brain Tumors In Children Pediatric Brain Tumor Diagnosis Family ... or Complete our contact form Adolescent & Pediatric Brain Tumors Brain Tumors In Children Pediatric Brain Tumor Diagnosis Family ...

  1. Children's perceptions of gender discrimination.

    PubMed

    Spears Brown, Christia; Bigler, Rebecca S

    2004-09-01

    Children (N = 76; ages 5-10 years) participated in a study designed to examine perceptions of gender discrimination. Children were read scenarios in which a teacher determined outcomes for 2 students (1 boy and 1 girl). Contextual information (i.e., teacher's past behavior), the gender of the target of discrimination (i.e., student), and the gender of the perpetrator (i.e., teacher) were manipulated. Results indicated that older children were more likely than younger children to make attributions to discrimination when contextual information suggested that it was likely. Girls (but not boys) were more likely to view girls than boys as victims of discrimination, and children with egalitarian gender attitudes were more likely to perceive discrimination than were their peers. PMID:15355161

  2. The Digital Absurd

    ERIC Educational Resources Information Center

    Hodges, Steve

    2010-01-01

    I believe that the concept of the absurd, as described in philosophy and reflected in works of drama and literature, provides an unusual and helpful perspective from which to view the emerging field of digital media. In my opinion, absurd principles can help us understand the mixed feelings we may have when engaging with digital media: joy and…

  3. Navigate the Digital Rapids

    ERIC Educational Resources Information Center

    Lindsay, Julie; Davis, Vicki

    2010-01-01

    How can teachers teach digital citizenship when the digital landscape is changing so rapidly? How can teachers teach proper online social interactions when the students are outside their classroom and thus outside their control? Will encouraging students to engage in global collaborative environments land teachers in hot water? These are the…

  4. Educating Digital Citizens

    ERIC Educational Resources Information Center

    Tan, Thomas

    2011-01-01

    Digital citizenship is how educators, citizens, and parents can teach where the lines of cyber safety and ethics are in the interconnected online world their students will inhabit. Aside from keeping technology users safe, digital citizenship also prepares students to survive and thrive in an environment embedded with information, communication,…

  5. Digital Media and Learning

    ERIC Educational Resources Information Center

    John D. and Catherine T. MacArthur Foundation, 2012

    2012-01-01

    MacArthur launched the digital media and learning initiative in 2006 to explore how digital media are changing the way young people learn, socialize, communicate, and play. Since 2006, the Foundation has awarded grants totaling more than $100 million for research, development of innovative new technologies, new learning environments for youth,…

  6. Digital automatic gain control

    NASA Technical Reports Server (NTRS)

    Uzdy, Z.

    1980-01-01

    Performance analysis, used to evaluated fitness of several circuits to digital automatic gain control (AGC), indicates that digital integrator employing coherent amplitude detector (CAD) is best device suited for application. Circuit reduces gain error to half that of conventional analog AGC while making it possible to automatically modify response of receiver to match incoming signal conditions.

  7. Digital rotation measurement unit

    DOEpatents

    Sanderson, S.N.

    1983-09-30

    A digital rotation indicator is disclosed for monitoring the position of a valve member having a movable actuator. The indicator utilizes mercury switches adapted to move in cooperation with the actuator. Each of the switches produces an output as it changes state when the actuator moves. A direction detection circuit is connected to the switches to produce a first digital signal indicative of the direction of rotation of the actuator. A count pulse generating circuit is also connected to the switches to produce a second digital pulse signal having count pulses corresponding to a change of state of any of the mercury switches. A reset pulse generating circuit is provided to generate a reset pulse each time a count pulse is generated. An up/down counter is connected to receive the first digital pulse signal and the second digital pulse signal and to count the pulses of the second digital pulse signal either up or down depending upon the instantaneous digital value of the first digital signal whereby a running count indicative of the movement of the actuator is maintained.

  8. Occupying the Digital Humanities

    ERIC Educational Resources Information Center

    Rice, Jeff

    2013-01-01

    This essay questions the digital humanities' dependence on interpretation and critique as strategies for reading and responding to texts. Instead, the essay proposes suggestion as a digital rhetorical practice, one that does not replace hermeneutics, but instead offers alternative ways to respond to texts. The essay uses the Occupy movement as an…

  9. The Digital Vaults

    ERIC Educational Resources Information Center

    Isaacs, Suzanne; Potter, Lee Ann

    2008-01-01

    This article explores the Digital Vaults and offers suggestions in introducing this site to students. The Digital Vaults, inspired by the permanent Public Vaults exhibition launched by the National Archives in 2004, is not just another website, but it designed to be an online exhibit and teaching tool, by offering both exposure to historical…

  10. Digital Pinhole Camera

    ERIC Educational Resources Information Center

    Lancor, Rachael; Lancor, Brian

    2014-01-01

    In this article we describe how the classic pinhole camera demonstration can be adapted for use with digital cameras. Students can easily explore the effects of the size of the pinhole and its distance from the sensor on exposure time, magnification, and image quality. Instructions for constructing a digital pinhole camera and our method for…

  11. Digital Collections Inventory Report.

    ERIC Educational Resources Information Center

    McClung, Patricia A.

    This report is intended to inform and stimulate discussion on digital library programs as well as the potential usefulness, scope, and desired features of future inventories of online digital collections. It describes a joint project by the Commission on Preservation and Access and the Council on Library Resources to determine the extent to which…

  12. Cresting the Digital Divide

    ERIC Educational Resources Information Center

    Gregory, Kay; Steelman, Joyce

    2008-01-01

    Catawba Valley Community College has introduced digital storytelling (DS), an innovative instructional method that has produced extraordinary results. Digital storytelling uses affordable software to craft powerful multimedia presentations of student writing. Students create 3-to-4-minute movies with images, voiceovers, and music. This project…

  13. Digital Video Editing

    ERIC Educational Resources Information Center

    McConnell, Terry

    2004-01-01

    Monica Adams, head librarian at Robinson Secondary in Fairfax country, Virginia, states that librarians should have the technical knowledge to support projects related to digital video editing. The process of digital video editing and the cables, storage issues and the computer system with software is described.

  14. Will Digital Texts Succeed?

    ERIC Educational Resources Information Center

    Acker, Stephen R.

    2008-01-01

    With faculty changing instructional practices to take advantage of customizable, focused content (and digital delivery of that content), many people assume that digital distribution is the answer to bringing the costs of course content delivery in line. But the picture just isn't that simple. A wide continuum of options is available to faculty and…

  15. Shaping Digital Library Content.

    ERIC Educational Resources Information Center

    Miller, Rush G.

    2002-01-01

    Explores issues related to the selection and purchase of digital content in academic libraries, including commercially-produced databases, electronic journals, and books and other electronic resources that are purchased from vendors; and in-house digitization projects. Considers the degree to which standard collection management principles apply.…

  16. Optimization of digital designs

    NASA Technical Reports Server (NTRS)

    Whitaker, Sterling R. (Inventor); Miles, Lowell H. (Inventor)

    2009-01-01

    An application specific integrated circuit is optimized by translating a first representation of its digital design to a second representation. The second representation includes multiple syntactic expressions that admit a representation of a higher-order function of base Boolean values. The syntactic expressions are manipulated to form a third representation of the digital design.

  17. Music Instruction Goes Digital

    ERIC Educational Resources Information Center

    Demski, Jennifer

    2011-01-01

    Faced with meager enrollment in band, orchestra, and choir programs, schools are using digital technology to excite students about creating music on today's terms. This article discusses how music educators reinvent their profession by acknowledging and incorporating the way students interact with music today--digitally. Bill Evans, a music…

  18. Digital Image Access & Retrieval.

    ERIC Educational Resources Information Center

    Heidorn, P. Bryan, Ed.; Sandore, Beth, Ed.

    Recent technological advances in computing and digital imaging technology have had immediate and permanent consequences for visual resource collections. Libraries are involved in organizing and managing large visual resource collections. The central challenges in working with digital image collections mirror those that libraries have sought to…

  19. Creating Digital Authors

    ERIC Educational Resources Information Center

    Zoch, Melody; Langston-DeMott, Brooke; Adams-Budde, Melissa

    2014-01-01

    Elementary students find themselves engaged and learning at a digital writing camp. The authors find that such elementary students usually have limited access to technology at home and school, and posit that teachers should do all they can to give them more access to and experience in digital composing. Students were motivated and learned to use…

  20. Writing and Digital Media

    ERIC Educational Resources Information Center

    van Waes, Luuk, Ed.; Leijten, Marielle, Ed.; Neuwirth, Chris, Ed.

    2006-01-01

    Digital media has become an increasingly powerful force in modern society. This volume brings together outstanding European, American and Australian research in "writing and digital media" and explores its cognitive, social and cultural implications. In addition to presenting programs of original research by internationally known scholars from a…