Science.gov

Sample records for general population relation

  1. Are Autistic Traits in the General Population Related to Global and Regional Brain Differences?

    ERIC Educational Resources Information Center

    Koolschijn, P. Cédric M. P.; Geurts, Hilde M.; van der Leij, Andries R.; Scholte, H. Steven

    2015-01-01

    There is accumulating evidence that autistic-related traits in the general population lie on a continuum, with autism spectrum disorders representing the extreme end of this distribution. Here, we tested the hypothesis of a possible relationship between autistic traits and brain morphometry in the general population. Participants completed the…

  2. Age-related differences in internalizing psychopathology amongst the Australian general population.

    PubMed

    Sunderland, Matthew; Slade, Tim; Carragher, Natacha; Batterham, Philip; Buchan, Heather

    2013-11-01

    Two methodological criticisms have limited the reliability and validity of findings from previous studies that seek to examine change across the life span in levels of internalizing psychopathology using general population surveys. The first criticism involves the potential influence of cohort effects that confound true age-related changes whereas the second criticism involves the use of a single form of assessment to measure and compare levels of internalizing psychopathology. This study seeks to address these criticisms by modeling age-related change using multiple measures and multiple surveys. Data from 2 epidemiological surveys conducted 10 years apart in the Australian general population were combined and used for the current study. The latent construct of internalizing psychopathology was modeled using a combination of Diagnostic and Statistical Manual of Mental Disorders (4th ed.; DSM-IV; American Psychiatric Association, 1994) depression and anxiety diagnoses as well as items from the Kessler Psychological Distress scale (K10; Kessler et al., 2002). Confirmatory factor analysis (CFA) indicated that a single internalizing dimension provided good model fit to the data. Multigroup CFA indicated that strict measurement invariance of the model can be assumed across survey administrations and age bands, justifying comparisons of mean differences in latent trait levels. Significant changes in mean levels of latent internalizing psychopathology were evident between respondents aged 30-39 years old in 1997 and respondents aged 40-49 years old in 2007, suggesting a minor but significant increase in psychopathology across middle age. By contrast, a minor but significant decrease in psychopathology was noted when transitioning from late middle age (50-59 years old) to old age (60-69 years old). The majority of individuals in the general population will experience constant levels of internalizing psychopathology as they age, suggesting that the construct is relatively

  3. Relation between psychological strain and carotid atherosclerosis in a general population

    PubMed Central

    Wolff, B; Grabe, H J; Völzke, H; Lüdemann, J; Kessler, C; Dahm, J B; Freyberger, H J; John, U; Felix, S B

    2005-01-01

    Objective: To investigate the hypothesis that psychological strain is related to carotid atherosclerosis in a large general population sample. Methods: Intima–media thickness and the prevalence of atherosclerotic plaques in the carotid arteries were quantitatively assessed by high resolution ultrasound among 2164 participants (1112 women and 1052 men, aged 45 to 75 years) of the SHIP (study of health in Pomerania), an epidemiological survey of a random sample of the population of north eastern Germany. Psychological strain was measured by 13 items reflecting typical psychological complaints. Each item was graded by the study participants on a four point scale (from 0, absent, to 3, severe) and a psychological strain score was generated by summing these 13 items. Results: Mean psychological strain score was 10.8 (7.0) (median score 10) among women and 8.5 (6.2) (median score 8) among men. Psychological strain did not predict carotid intima–media thickness among either men or women. However, after adjustment for covariates, high psychological strain and carotid plaques were independently and linearly related, with plaque prevalence odds of 1.03 (95% confidence interval (CI) 1.01 to 1.05, p  =  0.009) per increment of the psychological strain score among women and 1.04 (95% CI 1.01 to 1.07, p  =  0.003) among men. Conclusions: This study identified a relation between general psychological strain and carotid atherosclerosis. PMID:15772199

  4. Health-related quality of life in Korean lymphoma survivors compared with the general population.

    PubMed

    Kim, Soo Hyun; Kim, Im-Ryung; Kim, So Hee; Lee, Suyeon; Ok, Onam; Kim, Won Seog; Suh, Cheolwon; Lee, Moon Hee

    2014-09-01

    The objective of this study was to evaluate the health-related quality of life (HRQOL) of lymphoma survivors, to compare it with that of the general population, and to identify its predictors in lymphoma survivors. We enrolled 837 participants (mean age, 54.6 years; mean time since diagnosis, 6.3 years) with a history of Hodgkin's lymphoma (HL) (n = 58) or non-Hodgkin's lymphoma (NHL) (n = 779) who had been treated at any of three Korean hospitals from 1989 through 2010. For controls, we selected 1,000 subjects randomly from a representative Korean population. We administered the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 and the Hospital Anxiety and Depression Scale. Overall, the HRQOL in both groups of survivors and the general population were comparable, but we observed clinically meaningful worse social functioning in NHL survivors (p < 0.001) and more severe fatigue in HL survivors (p < 0.001) than in the general population. Analysis of covariance revealed no clinically meaningful difference in HRQOL associated with age or sex. Survivors who received peripheral blood stem cell transplants showed clinically meaningful worse role (p = 0.001) and social (p < 0.001) functioning than those who were treated with first-line chemotherapy alone. In multivariate analyses, fatigue, depression, and financial difficulties emerged as the strongest predictors for almost all subscales of functioning and global quality of life. Interventions for alleviating fatigue, depression, and financial difficulties are needed to enhance the HRQOL of Korean lymphoma survivors. PMID:24947794

  5. The Relation of Moderate Alcohol Consumption to Hyperuricemia in a Rural General Population

    PubMed Central

    Li, Zhao; Guo, Xiaofan; Liu, Yamin; Chang, Ye; Sun, Yingxian; Zhu, Guangshuo; Abraham, Maria Roselle

    2016-01-01

    Background: although alcohol abuse is known to increase serum uric acid, the relation between moderate drinking and uric acid have remained poorly understood. We performed this study to evaluate whether different alcohol consumption level has different effects on the risk of hyperuricemia based on a rural general population. Method: multi-stage cluster sampling method was used to select a representative sample of individuals aged 35 years or older. Participants were asked to provide information about their alcohol consumption. Data regarding the demographic and lifestyle characteristics and the blood biochemical indexes of these participants were collected by well-trained personnel. Results: in total, 11,039 participants aged 35 years or older were included (4997 men and 6042 women). The prevalence of hyperuricemia in the different male alcohol consumption groups was 11.9% in non-drinkers, 12.6% in moderate drinkers, and 16.3% in heavy drinkers (p < 0.001). In females, the rates were 6.3% in non-drinkers, 8.1% in moderate drinkers, and 6.6% for heavy drinkers (p = 0.818). In males, multivariate logistic regression analyses shows heavy drinkers had an approximately 1.7-fold higher risk of hyperuricemia (OR: 1.657, 95% CI: 1.368 to 2.007, p < 0.001) than non-drinkers; moderate drinkers did not experience a significant increase in risk (OR: 1.232, 95% CI: 0.951 to 1.596, p = 0.114)). Multivariate logistic regression analyses of females showed that, compared with non-drinkers, neither moderate nor heavy drinkers had a significantly increased risk of hyperuricemia (OR: 1.565, 95% CI: 0.521 to 4.695, p = 0.425 for heavy drinkers; OR: 0.897, 95% CI: 0.117 to 6.855, p = 0.916 for moderate drinkers). Conclusions: heavy alcohol consumption increased the risk of hyperuricemia for males but not for females. Among both males and females, moderate alcohol consumption did not increase the risk of hyperuricemia. PMID:27447659

  6. Heart Rate Variability and Sleep-Related Breathing Disorders in the General Population.

    PubMed

    Aeschbacher, Stefanie; Bossard, Matthias; Schoen, Tobias; Schmidlin, Delia; Muff, Christoph; Maseli, Anna; Leuppi, Jörg D; Miedinger, David; Probst-Hensch, Nicole M; Schmidt-Trucksäss, Arno; Risch, Martin; Risch, Lorenz; Conen, David

    2016-09-15

    Obstructive sleep apnea seems to have an important influence on the autonomic nervous system. In this study, we assessed the relations of sleep apnea-related parameters with 24-hour heart rate variability (HRV) in a large population of young and healthy adults. Participants aged 25 to 41 years with a body mass index <35 kg/m(2) and without known obstructive sleep apnea were included in a prospective population-based cohort study. HRV was assessed using 24-hour electrocardiographic monitoring. The SD of all normal RR intervals (SDNN) was used as the main HRV variable. Apnea-Hypopnea Index (AHI) and oxygen desaturation index (ODI) were obtained from nighttime pulse oximetry with nasal airflow measurements. We defined sleep-related breathing disorders as an AHI ≥5 or an ODI ≥5. Multivariable regression models were constructed to assess the relation of HRV with either AHI or ODI. Median age of the 1,255 participants was 37 years, 47% were men, and 9.6% had an AHI ≥5. Linear inverse associations of SDNN across AHI and ODI groups were found (p for trend = 0.006 and 0.0004, respectively). The β coefficients (95% CI) for the relation between SDNN and elevated AHI were -0.20 (-0.40 to -0.11), p = 0.04 and -0.29 (-0.47 to -0.11), p = 0.002 for elevated ODI. After adjustment for 24-hour heart rate, the same β coefficients (95% CI) were -0.06 (-0.22 to 0.11), p = 0.51 and -0.14 (-0.30 to 0.01), p = 0.07, respectively. In conclusion, even early stages of sleep-related breathing disorders are inversely associated with HRV in young and healthy adults, suggesting that they are tightly linked with autonomic dysfunction. However, HRV and 24-hour heart rate seem to have common information. PMID:27553103

  7. Sleep Hygiene Pattern and Behaviors and Related Factors among General Population in West Of Iran

    PubMed Central

    Khazaie, Habibolah; Chehri, Azita; Sadeghi, Kheirollah; Heydarpour, Fatemeh; Soleimani, Akram; Rezaei, Zahra

    2016-01-01

    Introduction: Sleep hygiene was found as an important predictor for sleep quality. People’s sleep hygiene can have a major role in their daily function. The purpose of the study was to determine sleep hygiene patterns and sleep hygiene behaviors and factors affecting them in the general population of Kermanshah, Iran. Material and methods: In this cross-sectional study, 1829 men and 1262 women were selected randomly from 50 clusters of different parts of the city. The inclusion criteria were age between 12 and 65 years and living in Kermanshah. The exclusion criteria were psychiatric disorder and known general medical conditions that affecting sleep. The data collection instruments were demographic questionnaire and Sleep Hygiene Questionnaire, consisted of 13 items about biological rhythm and bed room environment and behaviors that affecting sleep. Data were analyzed by using SPSS version 16 software. Results: The highest percentage was obtained for irregular woke and went up from day to day or at weekend and holidays (74.8%). Only 213 (6.9%) participants were classified as having good sleep hygiene (score 12-14). The mean age of very poor, poor, moderate, and good sleepers was 34.8 ± 14.4, 33.7 ± 17.4, 36.5 ± 13.8, and 35 ± 13.7years, respectively. There were significant differences between the age of poor and moderate sleepers and also sleep hygiene patterns with respect to sex, education level and job. Conclusion: Poor sleep hygiene were more frequent in Iranian peoples and the major problem in sleep hygiene in our study was inappropriate sleep schedule. PMID:27045403

  8. Health-Related Quality of Life among Artisanal Fisherwomen/Shellfish Gatherers: Lower than the General Population

    PubMed Central

    Müller, Juliana dos Santos; Falcão, Ila Rocha; Couto, Maria Carolina Barreto Moreira; Viana, Wendel da Silva; Alves, Ivone Batista; Viola, Denise Nunes; Woods, Courtney Georgette; Rêgo, Rita Franco

    2016-01-01

    Quality of life is an indicator of how well one perceives that he/she is functioning physically and mentally. The aim of this paper is to determine the health-related quality of life (HRQOL) of artisanal fisherwomen/shellfish gatherers from the Saubara municipality in Bahia, Brazil in comparison to the general population. A structured questionnaire was administered to a sample of 209 artisanal fisherwomen selected at random. The HRQOL questionnaire, known as the 36-Item Short-Form Health Survey version 1 (SF-36v01), was also used, having been translated and verified cross-culturally for the Brazilian population. Sociodemographic, lifestyle and comorbidity information was also collected. Chronic diseases and indicators of musculoskeletal disorders (MSDs) were self-reported. The study population consisted primarily of individuals between 30 and 45 years of age (78%), of self-classified races black or brown (96.2%), with no more than an elementary school education (77%) and married (64.6%). In all the SF-36v01 dimensions, the values in the sample were lower than in the general population of Brazil, which was used as the reference population. In the “Physical Health” domain (Physical Functioning; Physical Role Limitations; Bodily Pain; General Health Perception) a tendency toward a lower health-related quality of life was observed among those who were older, had a lower education level, and had a prevalence of MSDs, hypertension or arthritis. The interference of health conditions linked to the fisherwomen’s work activities may contribute to lower HRQOL in all analyzed aspects, in comparison to the general population. In light of these findings, public health policies must consider these informal workers who contribute greatly to Brazil’s economy and food system. PMID:27164118

  9. Health-Related Quality of Life among Artisanal Fisherwomen/Shellfish Gatherers: Lower than the General Population.

    PubMed

    Müller, Juliana Dos Santos; Falcão, Ila Rocha; Couto, Maria Carolina Barreto Moreira; Viana, Wendel da Silva; Alves, Ivone Batista; Viola, Denise Nunes; Woods, Courtney Georgette; Rêgo, Rita Franco

    2016-01-01

    Quality of life is an indicator of how well one perceives that he/she is functioning physically and mentally. The aim of this paper is to determine the health-related quality of life (HRQOL) of artisanal fisherwomen/shellfish gatherers from the Saubara municipality in Bahia, Brazil in comparison to the general population. A structured questionnaire was administered to a sample of 209 artisanal fisherwomen selected at random. The HRQOL questionnaire, known as the 36-Item Short-Form Health Survey version 1 (SF-36v01), was also used, having been translated and verified cross-culturally for the Brazilian population. Sociodemographic, lifestyle and comorbidity information was also collected. Chronic diseases and indicators of musculoskeletal disorders (MSDs) were self-reported. The study population consisted primarily of individuals between 30 and 45 years of age (78%), of self-classified races black or brown (96.2%), with no more than an elementary school education (77%) and married (64.6%). In all the SF-36v01 dimensions, the values in the sample were lower than in the general population of Brazil, which was used as the reference population. In the "Physical Health" domain (Physical Functioning; Physical Role Limitations; Bodily Pain; General Health Perception) a tendency toward a lower health-related quality of life was observed among those who were older, had a lower education level, and had a prevalence of MSDs, hypertension or arthritis. The interference of health conditions linked to the fisherwomen's work activities may contribute to lower HRQOL in all analyzed aspects, in comparison to the general population. In light of these findings, public health policies must consider these informal workers who contribute greatly to Brazil's economy and food system. PMID:27164118

  10. Determinants of Health-Related Quality of Life in School-Aged Children: A General Population Study in the Netherlands

    PubMed Central

    Houben-van Herten, Marieke; Bai, Guannan; Hafkamp, Esther; Landgraf, Jeanne M.; Raat, Hein

    2015-01-01

    Background Health related quality of life is the functional effect of a medical condition and/or its therapy upon a patient, and as such is particularly suitable for describing the general health of children. The objective of this study was to identify and confirm potential determinants of health-related quality of life in children aged 4-11 years in the general population in the Netherlands. Understanding such determinants may provide insights into more targeted public health policy. Methods As part of a population based cross sectional study, the Child Health Questionnaire (CHQ) Parental Form 28 was used to measure health-related quality of life in school-aged children in a general population sample. Parents of 10,651 children aged 4-11 years were interviewed from January 2001 to December 2009. Results Multivariate and regression analyses demonstrated a declined CHQ Physical Summary score for children who had >1 conditions, disorders or acute health complaints and who were greater consumers of healthcare; children with a non-western immigrant background; and children whose parents did not work. Lower CHQ Psychosocial Summary score was reported for children who had >1 conditions, disorders or acute health complaints, boys, children of single parents and obese children. Conclusion The best predictors of health-related quality of life are variables that describe use of health care and the number of disorders and health complaints. Nonetheless, a number of demographic, socio-economic and family/environmental determinants contribute to a child’s health-related quality of life as well. PMID:25933361

  11. School-Related Stress, School Support, and Somatic Complaints: A General Population Study.

    ERIC Educational Resources Information Center

    Torsheim, Torbjorn; Wold, Bente

    2001-01-01

    Examined relationship between school-related stress, social support, and somatic complaints among Norwegian adolescents. Found that students with high levels of school-related stress had a higher odds ratio for weekly headache, abdominal pain, backache, dizziness, and coexisting somatic complaints. For social support, associations were weaker, but…

  12. Internet and Social Media For Health-Related Information and Communication in Health Care: Preferences of the Dutch General Population

    PubMed Central

    Engelen, Lucien JLPG; Berben, Sivera AA; Teerenstra, Steven; Samsom, Melvin; Schoonhoven, Lisette

    2013-01-01

    Background Health care is increasingly featured by the use of Web 2.0 communication and collaborative technologies that are reshaping the way patients and professionals interact. These technologies or tools can be used for a variety of purposes: to instantly debate issues, discover news, analyze research, network with peers, crowd-source information, seek support, and provide advice. Not all tools are implemented successfully; in many cases, the nonusage attrition rates are high. Little is known about the preferences of the Dutch general population regarding the use of the Internet and social media in health care. Objective To determine the preferences of the general population in the Netherlands regarding the use of the Internet and social media in health care. Methods A cross-sectional survey was disseminated via a popular Dutch online social network. Respondents were asked where they searched for health-related information, how they qualified the value of different sources, and their preferences regarding online communication with health care providers. Results were weighed for the Dutch population based on gender, age, and level of education using official statistics. Numbers and percentages or means and standard deviations were presented for different subgroups. One-way ANOVA was used to test for statistical differences. Results The survey was completed by 635 respondents. The Internet was found to be the number one source for health-related information (82.7%), closely followed by information provided by health care professionals (71.1%). Approximately one-third (32.3%) of the Dutch population search for ratings of health care providers. The most popular information topics were side effects of medication (62.5%) and symptoms (59.7%). Approximately one-quarter of the Dutch population prefer to communicate with a health care provider via social media (25.4%), and 21.2% would like to communicate via a webcam. Conclusions The Internet is the main source of health-related

  13. How Is Emotional Awareness Related to Emotion Regulation Strategies and Self-Reported Negative Affect in the General Population?

    PubMed Central

    Subic-Wrana, Claudia; Beutel, Manfred E.; Brähler, Elmar; Stöbel-Richter, Yve; Knebel, Achim; Lane, Richard D.; Wiltink, Jörg

    2014-01-01

    Objective The Levels of Emotional Awareness Scale (LEAS) as a performance task discriminates between implicit or subconscious and explicit or conscious levels of emotional awareness. An impaired awareness of one's feeling states may influence emotion regulation strategies and self-reports of negative emotions. To determine this influence, we applied the LEAS and self-report measures for emotion regulation strategies and negative affect in a representative sample of the German general population. Sample and Methods A short version of the LEAS, the Hospital Anxiety and Depression Scale (HADS) and the Emotion Regulation Questionnaire (ERQ), assessing reappraisal and suppression as emotion regulation strategies, were presented to N = 2524 participants of a representative German community study. The questionnaire data were analyzed with regard to the level of emotional awareness. Results LEAS scores were independent from depression, but related to self-reported anxiety. Although of small or medium effect size, different correlational patters between emotion regulation strategies and negative affectivity were related to implict and explict levels of emotional awareness. In participants with implicit emotional awareness, suppression was related to higher anxiety and depression, whereas in participants with explicit emotional awareness, in addition to a positive relationship of suppression and depression, we found a negative relationship of reappraisal to depression. These findings were independent of age. In women high use of suppression and little use of reappraisal were more strongly related to negative affect than in men. Discussion Our first findings suggest that conscious awareness of emotions may be a precondition for the use of reappraisal as an adaptive emotion regulation strategy. They encourage further research in the relation between subconsious and conscious emotional awareness and the prefarance of adaptive or maladaptive emotion regulation strategies The

  14. Environmental, occupational, and personal factors related to the prevalence of sick building syndrome in the general population.

    PubMed Central

    Norbäck, D; Edling, C

    1991-01-01

    Possible relations between prevalence of sick building syndrome (SBS) and environmental, occupational, and personal factors were studied in a random sample (0.1%) of the general population aged 20-65 in a three county region in middle Sweden. Childhood exposure to environmental tobacco smoke from smoking mothers and a childhood in urban areas was related to SBS symptoms. Current urban residency, fresh paint, and preschool children in the dwelling were also related to symptoms. Other residential factors such as age of building, type of building, degree of crowding, mechanical ventilation, or signs of moisture or mould growth were not related to symptoms. Other factors related to symptoms were history of atopy, allergy to nickel, proneness to infection, hyperreactivity, static electricity, work with video display units (VDU), work satisfaction, and climate of cooperation at work. Age, sex, marital state, education level, work stress, obesity, current or earlier smoking, regular physical exercise, or occupational exposure to chemicals did not correlate with symptoms. Women had a higher proportion of symptoms than men but these differences were not significant when adjusting for differences in allergy to nickel, hyperreactivity, and proneness to infection. Maternal smoking was related to a twofold increase of both atopy and allergy to nickel in the adult offspring. Eye symptoms were most common in administrative, managerial, and service work. Airway symptoms were most common in transport and communication work. Dermal symptoms were most common in professional and technical and related work. General symptoms were most common in service, health, hospital, and social work. The lowest prevalence of symptoms was found in agricultural, forestry, and sales work. Women and subjects allergic to nickel worked more often in occupations without exposure to chemicals, but no evidence was found for selection mechanisms causing sensitive persons to move from exposed to unexposed

  15. Prevalence of cold-related complaints, symptoms and injuries in the general population: the FINRISK 2002 cold substudy

    NASA Astrophysics Data System (ADS)

    Raatikka, Veli-Pekka; Rytkönen, Mika; Näyhä, Simo; Hassi, Juhani

    2007-05-01

    The prevalence of cold-related complaints and symptoms in the general population has remained unknown. As part of the nationwide FINRISK 2002 health survey performed in Finland, 8,723 people aged 25 64 years filled in a questionnaire asking about the number of hours spent weekly in cold air, their sensations during cold exposure, cold-related complaints, symptoms of diseases, and degradation of performance. Cold thermal sensations at +5°C to -5°C were reported by 35% of men and 46% of women. Almost all subjects reported at least some cold-related complaints, most commonly musculoskeletal pain (men 30%, women 27%), followed by respiratory (25% / 29%), white finger (15% / 18%) and episodic peripheral circulation symptoms (12% / 15%). Decreased mental or physical performance in cold was reported by 75% of men and 70% of women, most commonly impairing manual dexterity and tactile sense. With declining temperature, the first symptom to emerge was pain in the elbow or the forearm (at -3°C), followed by increased excretion of mucus from the lungs (-5°C), while most other symptoms appeared only at lower temperatures of -15°C to -20°C. Most symptoms showed little or no association with the weekly duration of exposure, with the exception of cold-induced pain at most sites. Although, in general, Finns are well adapted to the cold climate, the high prevalence of cold-related complaints poses a challenge to the health care system in terms of decreased performance and the possibility that such symptoms predict more serious health effects, such as increased mortality.

  16. How Providing Mentoring Relates to Career Success and Organizational Commitment: A Study in the General Managerial Population

    ERIC Educational Resources Information Center

    Bozionelos, Nikos; Bozionelos, Giorgos; Kostopoulos, Konstantinos; Polychroniou, Panagiotis

    2011-01-01

    Purpose: This study aims to investigate the relationship of mentoring provided with career success and organizational commitment in the general managerial population. Design/methodology/approach: Participants were 194 native British who were employed in a variety of jobs, professions and industries in the United Kingdom. Findings: Mentoring…

  17. Forces in General Relativity

    ERIC Educational Resources Information Center

    Ridgely, Charles T.

    2010-01-01

    Many textbooks dealing with general relativity do not demonstrate the derivation of forces in enough detail. The analyses presented herein demonstrate straightforward methods for computing forces by way of general relativity. Covariant divergence of the stress-energy-momentum tensor is used to derive a general expression of the force experienced…

  18. Experiences of possession and paranormal phenomena among women in the general population: are they related to traumatic stress and dissociation?

    PubMed

    Sar, Vedat; Alioğlu, Firdevs; Akyüz, Gamze

    2014-01-01

    This study sought to determine the prevalence of experiences of possession and paranormal phenomena (PNP) in the general population and their possible relations to each other and to traumatic stress and dissociation. The study was conducted on a representative female sample recruited from a town in central eastern Turkey. The Dissociative Disorders Interview Schedule, the posttraumatic stress disorder (PTSD) and borderline personality disorder sections of the Structured Clinical Interviews for DSM-IV Axis-I and Personality Disorders, and the Childhood Abuse and Neglect Questionnaire were administered to 628 women. Of these, 127 (20.2%) women reported at least 1 type of PNP and 13 (2.1%) women reported possession. Women with a dissociative disorder reported all types of possession and PNP (except telepathy) more frequently than those without. Whereas women with a trauma history in childhood and adulthood or PTSD reported possession more frequently than those without, PNP were associated with childhood trauma only. Factor analysis yielded 4 dimensions: possession by and/or contact with nonhuman entities, extrasensory communications, possession by a human entity, and precognition. These factors correlated with number of secondary features of dissociative identity disorder and Schneiderian symptoms. Latent class analysis identified 3 groups. The most traumatized group, with predominantly dissociative and trauma-related disorders, had the highest scores on all factors. Notwithstanding their presence in healthy individuals, possession and PNP were associated with trauma and dissociation in a subgroup of affected participants. Both types of experience seem to be normal human capacities of experiencing that may be involved in response to traumatic stress. Given the small numbers, this study should be considered preliminary. PMID:24228817

  19. General relativity and cosmology

    NASA Astrophysics Data System (ADS)

    Bucher, Martin; Ni, Wei-Tou

    2015-10-01

    This year marks the 100th anniversary of Einstein’s 1915 landmark paper “Die Feldgleichungen der Gravitation” in which the field equations of general relativity were correctly formulated for the first time, thus rendering general relativity a complete theory. Over the subsequent hundred years, physicists and astronomers have struggled with uncovering the consequences and applications of these equations. This paper, which was written as an introduction to six chapters dealing with the connection between general relativity and cosmology that will appear in the two-volume book One Hundred Years of General Relativity: From Genesis and Empirical Foundations to Gravitational Waves, Cosmology and Quantum Gravity, endeavors to provide a historical overview of the connection between general relativity and cosmology, two areas whose development has been closely intertwined.

  20. General Relativity and Energy

    ERIC Educational Resources Information Center

    Jackson, A. T.

    1973-01-01

    Reviews theoretical and experimental fundamentals of Einstein's theory of general relativity. Indicates that recent development of the theory of the continually expanding universe may lead to revision of the space-time continuum of the finite and unbounded universe. (CC)

  1. Association of Serum Ferritin and Kidney Function with Age-Related Macular Degeneration in the General Population

    PubMed Central

    Oh, Il Hwan; Choi, Eun Young; Park, Joon-Sung; Lee, Chang Hwa

    2016-01-01

    Ferritin is considered to be a marker of the body’s iron stores and has a potential relationship with the systemic manifestations of inflammatory reactions. Data on the association between increased levels of serum ferritin and ocular problems are limited, particularly in relation to age-related macular degeneration (AMD). Serum ferritin levels, as a possible clinical parameter for predicting AMD, were analyzed in anthropometric, biochemical, and ophthalmologic data from a nation-wide, population-based, case-control study (KNHNES IV and V). All native Koreans aged ≥ 20 years and who had no medical illness were eligible to participate. Among them, 2.9% had AMD, and its prevalence was found to increase in the higher ferritin quintile groups (Ptrend < 0.0001). In multiple linear regression analysis, serum ferritin level was closely related to conventional risk factors for AMD. Comparison of early AMD with a control group showed that serum ferritin levels were closely associated with AMD (OR = 1.004, 95% CI = 1.002–1.006), and further adjustment for age, gender, serum iron, and kidney function did not reduce this association (OR = 1.003, 95% CI = 1.001–1.006). Furthermore, the relationship between ferritin quintile and early AMD was dose-dependent. Thus, an increased level of serum ferritin in a healthy person may be a useful indicator of neurodegenerative change in the macula. A large population-based prospective clinical study is needed to confirm these findings. PMID:27096155

  2. Association of Serum Ferritin and Kidney Function with Age-Related Macular Degeneration in the General Population.

    PubMed

    Oh, Il Hwan; Choi, Eun Young; Park, Joon-Sung; Lee, Chang Hwa

    2016-01-01

    Ferritin is considered to be a marker of the body's iron stores and has a potential relationship with the systemic manifestations of inflammatory reactions. Data on the association between increased levels of serum ferritin and ocular problems are limited, particularly in relation to age-related macular degeneration (AMD). Serum ferritin levels, as a possible clinical parameter for predicting AMD, were analyzed in anthropometric, biochemical, and ophthalmologic data from a nation-wide, population-based, case-control study (KNHNES IV and V). All native Koreans aged ≥ 20 years and who had no medical illness were eligible to participate. Among them, 2.9% had AMD, and its prevalence was found to increase in the higher ferritin quintile groups (Ptrend < 0.0001). In multiple linear regression analysis, serum ferritin level was closely related to conventional risk factors for AMD. Comparison of early AMD with a control group showed that serum ferritin levels were closely associated with AMD (OR = 1.004, 95% CI = 1.002-1.006), and further adjustment for age, gender, serum iron, and kidney function did not reduce this association (OR = 1.003, 95% CI = 1.001-1.006). Furthermore, the relationship between ferritin quintile and early AMD was dose-dependent. Thus, an increased level of serum ferritin in a healthy person may be a useful indicator of neurodegenerative change in the macula. A large population-based prospective clinical study is needed to confirm these findings. PMID:27096155

  3. Long-Term Health-Related Quality of Life in German Patients with Juvenile Idiopathic Arthritis in Comparison to German General Population

    PubMed Central

    Barth, Swaantje; Haas, Johannes-Peter; Schlichtiger, Jenny; Molz, Johannes; Bisdorff, Betty; Michels, Hartmut; Hügle, Boris; Radon, Katja

    2016-01-01

    Objective Aims of the study were to investigate health-related quality of life (HRQOL) in adult patients with former diagnosis of Juvenile Idiopathic Arthritis (JIA), to compare their HRQOL with the general population and to identify factors related to a poor outcome. Methods In 2012, a cross-sectional survey was performed by mailing a questionnaire to a large cohort of former and current patients of the German Centre for Rheumatology in Children and Adolescents. Only adult patients (≥18 years) with a diagnosis compatible with JIA were included (n = 2592; response 66%). The questionnaire included information about HRQOL (EQ5D), disease-related questions and socio-demographics. Prevalence and 95% confidence intervals (CI) of problems with mobility, self-care, usual activities, pain and anxiety/depression were standardized to the German general population. Factors associated with low HRQOL in JIA patients were identified using logistic regression models. Results Sixty-two percent of the study population was female; age range was 18–73 years. In all dimensions, JIA patients reported statistically significantly more problems than the general population with largest differences in the pain dimension (JIA patients 56%; 95%CI 55–58%; general population 28%; 26–29%) and the anxiety/depression dimension (28%; 27–29% vs. 4%; 4–5%). Lower HRQOL in JIA patients was associated with female sex, older age, lower level of education, still being under rheumatic treatment and disability. Conclusions HRQOL in adult JIA patients is considerably lower than in the general population. As this cohort includes historic patients the new therapeutic schemes available today are expected to improve HRQOL in future. PMID:27115139

  4. Matter in general relativity

    NASA Technical Reports Server (NTRS)

    Ray, J. R.

    1982-01-01

    Two theories of matter in general relativity, the fluid theory and the kinetic theory, were studied. Results include: (1) a discussion of various methods of completing the fluid equations; (2) a method of constructing charged general relativistic solutions in kinetic theory; and (3) a proof and discussion of the incompatibility of perfect fluid solutions in anisotropic cosmologies. Interpretations of NASA gravitational experiments using the above mentioned results were started. Two papers were prepared for publications based on this work.

  5. Exposure to war-related traumatic events, prevalence of PTSD, and general psychiatric morbidity in a civilian population from Southern Lebanon.

    PubMed

    Farhood, Laila; Dimassi, Hani; Lehtinen, Tuija

    2006-10-01

    The South of Lebanon has experienced prolonged armed conflict. The current study aims to investigate the degree of exposure to traumatic events and prevalence of posttraumatic stress disorder (PTSD) and nonspecific general psychiatric morbidity in a civilian population from the South of Lebanon. The design was cross-sectional with random sampling. War-related traumatic events and symptoms of PTSD were assessed by the Harvard Trauma Questionnaire and general psychiatric morbidity by the General Health Questionnaire (GHQ-28). Almost all participants, 97.7%, had experienced, witnessed, or heard of a war-related traumatic event. Current PTSD prevalence was 29.3%. PTSD symptoms correlated highly with GHQ-28 symptoms, r = .73 (p < .0001). The present study indicates a need for psychological interventions in the population and studies to assess such interventions. PMID:16946115

  6. General Relativity Today

    NASA Astrophysics Data System (ADS)

    Blandford, Roger D.

    2016-01-01

    A hundred years after its birth, general relativity has become a highly successful theory in the sese that it has passed many experimental and observational tests and finds widespread application to diverse set of cosmic phenomena. It remains an accurate research field as more tests are deployed, epitomized by the exciting prospect of detecting gravitational radiation directly. General realtivity is the essential foundation of modern cosmology and underlies our detailed description of the black holes and neutron stars that are ultimately responsible for the most powerful and dramatic cosmic sources. The interface with physics on both the largest and the smallest scales continues to be very fertile. In this talk I will attempt to highlight some key steps along the way to general relativity today.

  7. Lead exposure in the general population of the Metropolitan Area of Barcelona: blood levels and related factors.

    PubMed

    Solé, E; Ballabriga, A; Dominguez, C

    1998-12-11

    A cross-sectional study was conducted on 254 individuals not occupationally exposed to lead to determine the degree of lead exposure in the general population of the Metropolitan Area of Barcelona. Blood lead levels (BPb) were analysed by atomic absorption spectrophotometry and zinc protoporphyrin (ZPP) by haemofluorimetry. Blood lead levels were analysed with respect to individuals' age, sex, area of residence, the season of the year the blood was drawn and ZPP. Mean blood lead in our series was 0.22 +/- 0.011 mumol/l (mean +/- S.E.); no significant differences were found with respect to area of residence, sex or season. A linear relationship was observed between BPb and individuals' age (BPb = 0.08 + 0.05 x age; r = 0.37). The prevalence of lead intoxication (BPb > 0.48 mumol/l) was 7.1%. No linear relationship was observed between BPb and ZPP. ZPP determination does not appear to be a good screening method for lead intoxication since it presents low specificity and sensitivity values with an area below the ROC curve similar to the null value line (area below the curve = 0.5052, IC 95% = 0.443-0.568). We conclude that lead exposure does not constitute a serious health problem in the area studied, since BPb levels found are far below the toxic limit and the prevalence of intoxication is similar to that reported in other studies conducted in other developed countries. PMID:9926425

  8. A general methodology for population analysis

    NASA Astrophysics Data System (ADS)

    Lazov, Petar; Lazov, Igor

    2014-12-01

    For a given population with N - current and M - maximum number of entities, modeled by a Birth-Death Process (BDP) with size M+1, we introduce utilization parameter ρ, ratio of the primary birth and death rates in that BDP, which, physically, determines (equilibrium) macrostates of the population, and information parameter ν, which has an interpretation as population information stiffness. The BDP, modeling the population, is in the state n, n=0,1,…,M, if N=n. In presence of these two key metrics, applying continuity law, equilibrium balance equations concerning the probability distribution pn, n=0,1,…,M, of the quantity N, pn=Prob{N=n}, in equilibrium, and conservation law, and relying on the fundamental concepts population information and population entropy, we develop a general methodology for population analysis; thereto, by definition, population entropy is uncertainty, related to the population. In this approach, what is its essential contribution, the population information consists of three basic parts: elastic (Hooke's) or absorption/emission part, synchronization or inelastic part and null part; the first two parts, which determine uniquely the null part (the null part connects them), are the two basic components of the Information Spectrum of the population. Population entropy, as mean value of population information, follows this division of the information. A given population can function in information elastic, antielastic and inelastic regime. In an information linear population, the synchronization part of the information and entropy is absent. The population size, M+1, is the third key metric in this methodology. Namely, right supposing a population with infinite size, the most of the key quantities and results for populations with finite size, emerged in this methodology, vanish.

  9. Social network in long-term diseases: a comparative study in relatives of persons with schizophrenia and physical illnesses versus a sample from the general population.

    PubMed

    Magliano, Lorenza; Fiorillo, Andrea; Malangone, Claudio; De Rosa, Corrado; Maj, Mario

    2006-03-01

    This study compares the social network of a sample of 709 relatives of patients with schizophrenia, 646 relatives of patients with physical diseases, and 714 lay respondents, recruited in 30 randomly selected Italian areas, stratified for geographic location and population density. Each respondent was asked to fill in the Social Network Questionnaire. The social network was less extended and supportive in relatives of patients with schizophrenia than in those of patients with physical diseases and in the general population. Multivariate analyses revealed that social contacts were similarly reduced in relatives of patients with schizophrenia and physical diseases, while social support was significantly lower in relatives of patients with schizophrenia than in the other two groups. Social resources were higher in young respondents and in those living in rural areas. These results highlight the need to provide the families of those with long-term diseases with interventions aimed at increasing their social resources. PMID:16162379

  10. Tests of General Relativity

    SciTech Connect

    Kramer, Michael

    2011-09-22

    The last years have seen continuing activities in the exploration of our understanding of gravity, motivated by results from precision cosmology and new precision astrophysical experiments. At the centre of attention lies the question as to whether general relativity is the correct theory of gravity. In answering this question, we work not only towards correctly interpreting the phenomenon of 'dark energy' but also towards the goal of achieving a quantum theory of gravity. In these efforts, the observations of pulsars, especially those in binary systems, play an important role. Pulsars do not only provide the only evidence for the existence of gravitational waves so far, but they also provide precision tests of general relativity and alternative theories of gravity. This talk summarizes the current state-of-art in these experiments and looks into the future.

  11. General Relativity and Gravitation

    NASA Astrophysics Data System (ADS)

    Ashtekar, Abhay; Berger, Beverly; Isenberg, James; MacCallum, Malcolm

    2015-07-01

    Part I. Einstein's Triumph: 1. 100 years of general relativity George F. R. Ellis; 2. Was Einstein right? Clifford M. Will; 3. Cosmology David Wands, Misao Sasaki, Eiichiro Komatsu, Roy Maartens and Malcolm A. H. MacCallum; 4. Relativistic astrophysics Peter Schneider, Ramesh Narayan, Jeffrey E. McClintock, Peter Mészáros and Martin J. Rees; Part II. New Window on the Universe: 5. Receiving gravitational waves Beverly K. Berger, Karsten Danzmann, Gabriela Gonzalez, Andrea Lommen, Guido Mueller, Albrecht Rüdiger and William Joseph Weber; 6. Sources of gravitational waves. Theory and observations Alessandra Buonanno and B. S. Sathyaprakash; Part III. Gravity is Geometry, After All: 7. Probing strong field gravity through numerical simulations Frans Pretorius, Matthew W. Choptuik and Luis Lehner; 8. The initial value problem of general relativity and its implications Gregory J. Galloway, Pengzi Miao and Richard Schoen; 9. Global behavior of solutions to Einstein's equations Stefanos Aretakis, James Isenberg, Vincent Moncrief and Igor Rodnianski; Part IV. Beyond Einstein: 10. Quantum fields in curved space-times Stefan Hollands and Robert M. Wald; 11. From general relativity to quantum gravity Abhay Ashtekar, Martin Reuter and Carlo Rovelli; 12. Quantum gravity via unification Henriette Elvang and Gary T. Horowitz.

  12. Tachyons in general relativity

    SciTech Connect

    Schwartz, Charles

    2011-05-15

    We consider the motion of tachyons (faster-than-light particles) in the framework of general relativity. An important feature is the large contribution of low energy tachyons to the energy-momentum tensor. We also calculate the gravitational field produced by tachyons in particular geometric arrangements; and it appears that there could be self-cohering bundles of such matter. This leads us to suggest that such theoretical ideas might be relevant to major problems (dark matter and dark energy) in current cosmological models.

  13. HIV-related risk behaviors among the general population: a survey using Audio Computer-Assisted Self-Interview in 3 cities in Vietnam.

    PubMed

    Vu, Lan T H; Nadol, Patrick; Le, Linh Cu

    2015-03-01

    This study used a confidential survey method-namely, Audio Computer-Assisted Self-Interview (ACASI)-to gather data about HIV-related risk knowledge/behaviors among the general population in Vietnam. The study sample included 1371 people aged 15 to 49 years in 3 cities-Hanoi, Da nang, and Can Tho. Results indicated that 7% of participants had ever had nonconsensual sex, and 3.6% of them had ever had a one-night stand. The percentage of male participants reported to ever have sex with sex workers was 9.6% and to ever inject drugs was 4.3%. The proportion of respondents who had ever tested for HIV was 17.6%. The risk factors and attitudes reported in the survey indicate the importance of analyzing risk behaviors related to HIV infection among the general population. Young people, especially men in more urbanized settings, are engaging in risky behaviors and may act as a "bridge" for the transmission of HIV from high-risk groups to the general population in Vietnam. PMID:22743864

  14. Is a history of work-related low back injury associated with prevalent low back pain and depression in the general population?

    PubMed Central

    Hincapié, Cesar A; Cassidy, J David; Côté, Pierre

    2008-01-01

    Background Little is known about the role of prior occupational low back injury in future episodes of low back pain and disability in the general population. We conducted a study to determine if a lifetime history of work-related low back injury is associated with prevalent severity-graded low back pain, depressive symptoms, or both, in the general population. Methods We used data from the Saskatchewan Health and Back Pain Survey – a population-based cross-sectional survey mailed to a random, stratified sample of 2,184 Saskatchewan adults 20 to 69 years of age in 1995. Information on the main independent variable was gathered by asking respondents whether they had ever injured their low back at work. Our outcomes, the 6-month period prevalence of severity-graded low back pain and depressive symptoms during the past week, were measured with valid and reliable questionnaires. The associations between prior work-related low back injury and our outcomes were estimated through multinomial and binary multivariable logistic regression with adjustment for age, gender, and other important covariates. Results Fifty-five percent of the eligible population participated. Of the 1,086 participants who responded to the question about the main independent variable, 38.0% reported a history of work-related low back injury. A history of work-related low back injury was positively associated with low intensity/low disability low back pain (OR, 3.66; 95%CI, 2.48–5.42), with high intensity/low disability low back pain (OR, 4.03; 95%CI, 2.41–6.76), and with high disability low back pain (OR, 6.76; 95%CI, 3.80–12.01). No association was found between a history of work-related low back injury and depression (OR, 0.85; 95%CI, 0.55–1.30). Conclusion Our analysis shows an association between past occupational low back injury and increasing severity of prevalent low back pain, but not depression. These results suggest that past work-related low back injury may be an important risk

  15. Health-related quality of life and utility scores in people with mental disorders: a comparison with the non-mentally ill general population.

    PubMed

    Prigent, Amélie; Auraaen, Ane; Kamendje-Tchokobou, Blaise; Durand-Zaleski, Isabelle; Chevreul, Karine

    2014-03-01

    There is a lack of comparable health-related quality of life (HRQoL) and utility data across all mental disorders and all inpatient and outpatient settings. Our objective was to investigate the HRQoL and utility scores of people with mental disorders in France, treated in outpatient and inpatient settings, and to identify the HRQoL and utility score losses attributable to mental disorders compared to the non-mentally ill general population. A cross-sectional survey was conducted to assess HRQoL (SF-12) and utility scores of patients with mental disorders and followed in four psychiatric sectors in France. Scores were described by demographic and clinical characteristics and were then adjusted on age and gender and compared with those of the non-mentally ill general population. Median HRQoL and utility scores were significantly lower in patients with mental disorders than in the non-mentally ill general population; median differences amounted to 5.4 for the HRQoL physical score, to 11.8 for the HRQoL mental score and to 0.125 for the utility score. Our findings underscore the negative impact of mental disorders on HRQoL in France and provide a baseline to assess the global impact of current and future organizational changes in the mental health care system. PMID:24608903

  16. Health-Related Quality of Life and Utility Scores in People with Mental Disorders: A Comparison with the Non-Mentally Ill General Population

    PubMed Central

    Prigent, Amélie; Auraaen, Ane; Kamendje-Tchokobou, Blaise; Durand-Zaleski, Isabelle; Chevreul, Karine

    2014-01-01

    There is a lack of comparable health-related quality of life (HRQoL) and utility data across all mental disorders and all inpatient and outpatient settings. Our objective was to investigate the HRQoL and utility scores of people with mental disorders in France, treated in outpatient and inpatient settings, and to identify the HRQoL and utility score losses attributable to mental disorders compared to the non-mentally ill general population. A cross-sectional survey was conducted to assess HRQoL (SF-12) and utility scores of patients with mental disorders and followed in four psychiatric sectors in France. Scores were described by demographic and clinical characteristics and were then adjusted on age and gender and compared with those of the non-mentally ill general population. Median HRQoL and utility scores were significantly lower in patients with mental disorders than in the non-mentally ill general population; median differences amounted to 5.4 for the HRQoL physical score, to 11.8 for the HRQoL mental score and to 0.125 for the utility score. Our findings underscore the negative impact of mental disorders on HRQoL in France and provide a baseline to assess the global impact of current and future organizational changes in the mental health care system. PMID:24608903

  17. Directions in General Relativity

    NASA Astrophysics Data System (ADS)

    Hu, B. L.; Ryan, M. P., Jr.; Vishveshwara, C. V.

    2005-10-01

    Preface; Dieter Brill: a spacetime perspective; 1. Thawing the frozen formalism: the difference between observables and what we observe A. Anderson; 2. Jacobi's action and the density of states J. D. Brown and J. W. York; 3. Decoherence of correlation histories E. Calzetta and B. L. Hu; 4. The initial value problem in light of Ashtekar's variables R. Capovilla, J. Dell and T. Jacobson; 5. Status report on an axiomatic basis for functional integration P. Cartier and C. DeWitt-Morette; 6. Solution of the coupled Einstein constraints on asymptotically Euclidean manifolds Y. Choquet-Bruhat; 7. Compact Cauchy horizons and Cauchy surfaces P. Chrusciel and J. Isenberg; 8. The classical electron J. M. Cohen and E. Mustafa; 9. Gauge (in)variance, mass and parity in D=3 revisited S. Deser; 10. Triality, exceptional Lie groups and Dirac operators F. Flaherty; 11. The reduction of the state vector and limitations on measurement in the quantum mechanics of closed systems J. B. Hartle; 12 Quantum linearization instabilities of de Sitter spacetime A. Higuchi; 13. What is the true description of charged black holes? G. T. Horowitz; 14. Limits on the adiabatic index in static stellar models L. Lindblom and A. K. M. Masood-ul-Alam; 15. On the relativity of rotation B. Mashhoon; 16. Recent progress and open problems in linearization stability V. E. Moncrief; 17. Brill waves N. Ó Murchadha; 18. You can't get there from here: constraints on topology change K. Schleich and D. M. Witt; 19. Time, measurement and information loss in quantum cosmology L. Smolin; 20. Impossible measurements on quantum fields R. Sorkin; 21. A new condition implying the existence of a constant mean curvature foliation F. J. Tipler; 22. Maximal slices in stationary spacetimes with ergoregions R. M. Wald; 23. (1 + 1) - Dimensional methods for general relativity J. H. Yoon; 24. Coalescence of primal gravity waves to make cosmological mass without matter D. E. Holz, W. A. Miller, M. Wakano and J. A. Wheeler.

  18. How does emotional wellbeing relate to underachievement in a general population sample of young adolescents: a neurocognitive perspective

    PubMed Central

    van Batenburg-Eddes, Tamara; Jolles, Jelle

    2013-01-01

    Underachievement in school during early adolescence predicts future economic and personal difficulties. Particular neurocognitive skills on the domain of executive functions start to mature during adolescence. This fact and the physical and psychological changes typical for the transition from childhood to adulthood make adolescents vulnerable to emotional problems. The current study investigated the relationship between mild emotional problems which are highly prevalent among adolescents and underachievement in school, and the role of neurocognitive functioning in this relation. This study was conducted in a substantial sample of typical developing young adolescents who just made the transition to secondary education. Pupils were on average 12.5 years old (standard deviation 0.5), and 45% of the included sample were girls. Emotional wellbeing was associated with underachievement [Odds ratio (OR) 5.15, 95% confidence interval (CI) 3.06–8.68] after adjusting for background variables. Self-reported neurocognitive functioning partly explained the relation between emotional wellbeing and underachievement (OR 2.22, 95% CI 1.23–3.99), yet, emotional wellbeing remained statistically associated with underachievement after correcting for additional confounders (OR 1.99, 95% CI 1.08–3.66). The observed findings suggest that emotional wellbeing plays an essential role in underachievement during the first year of secondary education. PMID:24098291

  19. Smoking and Health-Related Quality of Life in the General Population. Independent Relationships and Large Differences According to Patterns and Quantity of Smoking and to Gender

    PubMed Central

    Coste, Joël; Quinquis, Laurent; D'Almeida, Samuel; Audureau, Etienne

    2014-01-01

    Background Relationships between smoking and health-related quality of life (HRQoL) in the general population remain unclear. Objectives To quantify the independent associations between smoking patterns and HRQoL and to identify any threshold or non-linear tendencies in these associations. Methods A national representative, cross-sectional household survey of the French general non institutionalized population included 7525 men and 8486 women, aged 25–64 year in 2003. Scores on the eight subscales of the Medical Outcomes Study 36-item Short Form were the primary outcomes. Linear regression analyses were used to evaluate the associations between HRQoL and smoking history, quantity of smoking and smoking cessation while controlling for various socio-economic variables, depression, alcohol dependence and pathological conditions. Analyses were conducted in 2013. Results Independent associations between smoking and HRQoL were found, including small positive associations for occasional or light smoking (up to 5 cigarettes per day), and larger and diffuse negative associations above this threshold. Much weaker associations and higher thresholds for negative HRQoL were found for women than for men. For ex-smokers of both genders, HRQoL was found to be better between 2 and 5 years after quitting. Conclusions Smoking was independently related to HRQoL, with large differences according to the pattern and quantity of smoking, and to gender. These results may have considerable relevance both for public health action and care of smokers. PMID:24637739

  20. Nonlocal General Relativity

    NASA Astrophysics Data System (ADS)

    Mashhoon, Bahram

    2014-12-01

    A brief account of the present status of the recent nonlocal generalization of Einstein's theory of gravitation is presented. The main physical assumptions that underlie this theory are described. We clarify the physical meaning and significance of Weitzenbock's torsion and emphasize its intimate relationship with the gravitational field, characterized by the Riemannian curvature of spacetime. In this theory, nonlocality can simulate dark matter; in fact, in the Newtonian regime, we recover the phenomenological Tohline-Kuhn approach to modified gravity. To account for the observational data regarding dark matter, nonlocality is associated with a characteristic length scale of order 1 kpc. The confrontation of nonlocal gravity with observation is briefly discussed.

  1. Seeds of General Relativity.

    ERIC Educational Resources Information Center

    Stauffer, Frederic R.

    1984-01-01

    Proposes novel methods of solving mechanics and dynamics problems by changing frames of reference. Uses these ideas to pursue Einstein's notions of inertial and uniformly rotating reference frames, gravitational and inertial mass, and the gravitational bending of light in relation to the simple original problem. (JM)

  2. Current sources of lead exposure and their relative contributions to the blood lead levels in the general adult population of Northern France: The IMEPOGE Study, 2008-2010.

    PubMed

    Tagne-Fotso, Romuald; Leroyer, Ariane; Howsam, Mike; Dehon, Betty; Richeval, Camille; Nisse, Catherine

    2016-01-01

    There is justification for limiting lead (Pb) exposure as much as possible, given its impact on health at low concentrations. Consequently, the aim of this study was to measure blood lead levels (BLL) and examine exposure factors related to BLL variations in the general adult population of northern France, a current and past industrial area. Two thousand inhabitants of northern France, aged between 20 and 59 years, were recruited using the quota method with caution. Blood lead levels were quantified by inductively coupled plasma-mass spectroscopy (ICP-MS), and variation factors were studied separately in men and women using multivariate stepwise linear and logistic regression models. The geometric mean of the BLL was 18.8 μg/L (95% confidence interval [CI]: 18.3-19.3). Occupational factors affected BLL only in men and represented 14% of total explained variance of BLL. External occupational factors significantly increasing mean levels of BLL were tobacco, consumption of some beverages (wine, coffee, tea, and/or tap water), raw vegetables, housing characteristics (built prior to 1948, Pb piping in the home) and do-it-yourself or leisure activities (paint stripping or rifle shooting). Consumption habits accounted together for 25% and 18% of the total explained variance, respectively, in men and women. Industrial environment did not significantly contribute to BLL variations. Blood lead levels observed in the general population of this industrial part of France did not appear to be excessively elevated compared to values found internationally. Nonetheless, these BLL remain a public health issue in regard to nonthreshold toxicity attributed to Pb. PMID:27074096

  3. Clinical course and risk factors of hepatitis C virus related liver disease in the general population: report from the Dionysos study

    PubMed Central

    Bellentani, S; Pozzato, G; Saccoccio, G; Crovatto, M; Croce, L; Mazzoran, L; Masutti, F; Cristianini, G; Tiribelli, C

    1999-01-01

    BACKGROUND—The severity, clinical course, and risk of hepatitis C virus (HCV) related chronic liver disease are still rather poorly defined.
AIMS—To investigate the prevalence, risk factors, and severity of HCV related liver disease in the general population, and investigate whether infection with a specific genotype is associated with an increased risk of cirrhosis or hepatocellular carcinoma.
METHODS—HCV RNA determination by polymerase chain reaction (PCR) and HCV genotyping were performed in all anti-HCV positive subjects belonging to the Dionysos study (6917 subjects). Diagnosis of cirrhosis and hepatocellular carcinoma was established by liver biopsy in all cases. All the data were analysed by univariate and multivariate statistics in all the cohort. To investigate the natural history of HCV infection, anti-HCV positive subjects were followed up every six months for three years with liver function tests and ultrasonograms.
RESULTS—The overall prevalence of HCV RNA positivity was 2.3%. Positivity increased progressively with age, and was higher in women (ratio of men to women = 0.7). Genotypes 1b and 2a were the most frequent (42 and 24% of HCV RNA positive patients), with a prevalence of 1 and 0.6% respectively. Intravenous drug use, blood transfusions received before 1990, history of previous hepatitis among the cohabiting, and history of animal (mainly dogs) bites were significantly (p<0.05) associated with HCV infection, independently of age and sex. Multivariate analysis showed that, independently of age, sex, and alcohol intake, genotype 1b infection, with or without coinfection with other genotypes, is the major risk factor associated with the presence of cirrhosis and/or hepatocellular carcinoma. During the three years of follow up, 57 (35%) of the HCV RNA positive subjects had consistently normal alanine aminotransferase and γ-glutamyltransferase values. Two of the 22 HCV RNA positive cirrhotic patients, all drinking more than 90

  4. A "Suicide Pill" for Older People: Attitudes of Physicians, the General Population, and Relatives of Patients Who Died after Euthanasia or Physician-Assisted Suicide in the Netherlands

    ERIC Educational Resources Information Center

    Rurup, Mette L.; Onwuteaka-Philipsen, Bregje D.; van der Wal, Gerrit; van der Heide, Agnes; van Der Maas, Paul J.

    2005-01-01

    In the Netherlands there has been ongoing debate in the past 10 years about the availability of a hypothetical "suicide pill", with which older people could end their life in a dignified way if they so wished. Data on attitudes to the suicide pill were collected in the Netherlands from 410 physicians, 1,379 members of the general population, and…

  5. [Does population ecology have general laws?].

    PubMed

    Turchin, P V

    2002-01-01

    There is a widespread opinion among ecologists that ecology lacks general laws. In this paper the author argues that this opinion is mistaken. Taking the case of population dynamics, the author points out that there are several very general law-like propositions that provide the theoretical basis for most population dynamics models that were developed to address specific issues. Some of these foundational principles, like the law of exponential growth, are logically very similar to certain law of physics (Newton's law of intertia, for example, is almost a direct analogue of exponential growth). The author discusses two other principles (population self-limitation and resource-consumer oscillations), as well as the more elementary postulates that underlie them. None of the "laws" that the author proposes for population ecology are new. Collectively ecologists have been using these general principles in guiding development of their models and experiments since the days of Lotka, Volterra, and Gause. PMID:11881213

  6. Speed limits in general relativity

    NASA Astrophysics Data System (ADS)

    Low, Robert J.

    1999-02-01

    Some standard results on the initial value problem of general relativity in matter are reviewed. These results are applied first to show that in a well defined sense, finite perturbations in the gravitational field travel no faster than light, and second to show that it is impossible to construct a warp drive as considered by Alcubierre (1994 The warp drive: hyper-fast travel within general relativity Class. Quantum Grav. 11 L73-7) in the absence of exotic matter.

  7. The General Fishbone Like Dispersion Relation

    NASA Astrophysics Data System (ADS)

    Zonca, Fulvio

    2015-12-01

    The following sections are included: * Introduction * Motivation and outline * Fundamental equations * The collisionless gyrokinetic equation * Vorticity equation * Quasi-neutrality condition * Perpendicular Ampère's law * Studying collective modes in burning plasmas * Ideal plasma equilibrium in the low-β limit * Approximations for the energetic population * Characteristic frequencies of particle motions * Alfvén wave frequency and wavelength orderings * Applications of the general theoretical framework * The general fishbone like dispersion relation * Properties of the fishbone like dispersion relation * Derivation of the fishbone like dispersion relation * Special cases of the fishbone like dispersion relation * Toroidal Alfvén Eigenmodes (TAE) * Alfvén Cascades * Summary and discussions * Acknowledgments * References

  8. Recent advances in general relativity

    SciTech Connect

    Janis, A.I.; Porter, J.R.

    1992-01-01

    The papers included in this book arose from a Discussion Conference on Recent Advances in General Relativity, which was held at the University of Pittsburgh, May 3-5, 1990, in honor of Ted Newman on the occasion of his 60th birthday. The book opens with a contribution outlining successes and problems of general relativity. Two contributions are devoted to quantum gravity. Discussions are included about general relativistic astrophysics, mathematics, and gravitational radiation. There are also workshop reports on classical gravity and quantum gravity.

  9. Spinning fluids in general relativity

    NASA Technical Reports Server (NTRS)

    Ray, J. R.; Smalley, L. L.

    1982-01-01

    General relativity field equations are employed to examine a continuous medium with internal spin. A variational principle formerly applied in the special relativity case is extended to the general relativity case, using a tetrad to express the spin density and the four-velocity of the fluid. An energy-momentum tensor is subsequently defined for a spinning fluid. The equations of motion of the fluid are suggested to be useful in analytical studies of galaxies, for anisotropic Bianchi universes, and for turbulent eddies.

  10. Quasilocal Hamiltonians in general relativity

    SciTech Connect

    Anderson, Michael T.

    2010-10-15

    We analyze the definition of quasilocal energy in general relativity based on a Hamiltonian analysis of the Einstein-Hilbert action initiated by Brown-York. The role of the constraint equations, in particular, the Hamiltonian constraint on the timelike boundary, neglected in previous studies, is emphasized here. We argue that a consistent definition of quasilocal energy in general relativity requires, at a minimum, a framework based on the (currently unknown) geometric well-posedness of the initial boundary value problem for the Einstein equations.

  11. Dimensional Analysis and General Relativity

    ERIC Educational Resources Information Center

    Lovatt, Ian

    2009-01-01

    Newton's law of gravitation is a central topic in the first-year physics curriculum. A lecturer can go beyond the physical details and use the history of gravitation to discuss the development of scientific ideas; unfortunately, the most recent chapter in this history, general relativity, is not covered in first-year courses. This paper discusses…

  12. General Relativity: Geometry Meets Physics

    ERIC Educational Resources Information Center

    Thomsen, Dietrick E.

    1975-01-01

    Observing the relationship of general relativity and the geometry of space-time, the author questions whether the rest of physics has geometrical explanations. As a partial answer he discusses current research on subatomic particles employing geometric transformations, and cites the existence of geometrical definitions of physical quantities such…

  13. Singing proficiency in the general population.

    PubMed

    Dalla Bella, Simone; Giguère, Jean-François; Peretz, Isabelle

    2007-02-01

    Most believe that the ability to carry a tune is unevenly distributed in the general population. To test this claim, we asked occasional singers (n=62) to sing a well-known song in both the laboratory and in a natural setting (experiment 1). Sung performances were judged by peers for proficiency, analyzed for pitch and time accuracy with an acoustic-based method, and compared to professional singing. The peer ratings for the proficiency of occasional singers were normally distributed. Only a minority of the occasional singers made numerous pitch errors. The variance in singing proficiency was largely due to tempo differences. Occasional singers tended to sing at a faster tempo and with more pitch and time errors relative to professional singers. In experiment 2 15 nonmusicians from experiment 1 sang the same song at a slow tempo. In this condition, most of the occasional singers sang as accurately as the professional singers. Thus, singing appears to be a universal human trait. However, two of the occasional singers maintained a high rate of pitch errors at the slower tempo. This poor performance was not due to impaired pitch perception, thus suggesting the existence of a purely vocal form of tone deafness. PMID:17348539

  14. Characteristics of hyperacusis in the general population.

    PubMed

    Paulin, Johan; Andersson, Linus; Nordin, Steven

    2016-01-01

    There is a need for better understanding of various characteristics in hyperacusis in the general population. The objectives of the present study were to investigate individuals in the general population with hyperacusis regarding demographics, lifestyle, perceived general health and hearing ability, hyperacusis-specific characteristics and behavior, and comorbidity. Using data from a large-scale population-based questionnaire study, we investigated individuals with physician-diagnosed (n = 66) and self-reported (n = 313) hyperacusis in comparison to individuals without hyperacusis (n = 2995). High age, female sex, and high education were associated with hyperacusis, and that trying to avoid sound sources, being able to affect the sound environment, and having sough medical attention were common reactions and behaviors. Posttraumatic stress disorder, chronic fatigue syndrome, generalized anxiety disorder, depression, exhaustion, fibromyalgia, irritable bowel syndrome, migraine, hearing impairment, tinnitus, and back/joint/muscle disorders were comorbid with hyperacusis. The results provide ground for future study of these characteristic features being risk factors for development of hyperacusis and/or consequences of hyperacusis. PMID:27569405

  15. Testing general relativity on accelerators

    NASA Astrophysics Data System (ADS)

    Kalaydzhyan, Tigran

    2015-11-01

    Within the general theory of relativity, the curvature of spacetime is related to the energy and momentum of the present matter and radiation. One of the more specific predictions of general relativity is the deflection of light and particle trajectories in the gravitational field of massive objects. Bending angles for electromagnetic waves and light in particular were measured with a high precision. However, the effect of gravity on relativistic massive particles was never studied experimentally. Here we propose and analyze experiments devoted to that purpose. We demonstrate a high sensitivity of the laser Compton scattering at high energy accelerators to the effects of gravity. The main observable - maximal energy of the scattered photons - would experience a significant shift in the ambient gravitational field even for otherwise negligible violation of the equivalence principle. We confirm predictions of general relativity for ultrarelativistic electrons of energy of tens of GeV at a current level of resolution and expect our work to be a starting point of further high-precision studies on current and future accelerators, such as PETRA, European XFEL and ILC.

  16. Energy loss in general relativity

    SciTech Connect

    Cooperstock, F.I.; Lim, P.H.

    1987-07-15

    Implicit assumptions regarding continuity in energy-loss calculations in general relativity are examined. The Arnowitt-Deser-Misner energy integral is treated in a new manner as a universal vehicle for energy loss. Two explicit examples are given: the electric dipole radiation flux is computed using general relativity as well as the gravitational-radiation flux from a linear mass quadrupole oscillator. In this approach, the latter is seen as a nonlinear problem in the sense that the lower-order metric serves as a source for the required order metric as computed within the wave front. Logarithmic terms which threaten to induce divergences, as has been found in other works, are averted by functions of integration which are required to sustain the gauge conditions and finally yield the usual fluxes.

  17. General Relativity and Spacetime Relationism.

    NASA Astrophysics Data System (ADS)

    Hoefer, Carl

    1992-01-01

    This dissertation takes up the project of showing that, in the context of the general theory of relativity (GTR), spacetime relationism is not a refuted or hopeless view, as many in the recent literature have maintained (John Earman, Michael Friedman, and others). Most of the challenges to the relationist view in General Relativity can be satisfactorily answered; in addition, the opposing absolutist and substantivalist views of spacetime can be shown to be problematic. The crucial burden for relationists concerned with GTR is to show that the realistic cosmological models, i.e. those that may be roughly accurate representations of our universe, satisfy Mach's ideas about the origin of inertia. This dissertation clears the way for and begins such a demonstration. After a brief discussion of the problem of the nature of spacetime and its history in the Introduction, chapters 2 and 3 provide conceptual analysis and criticism of contemporary philosophical arguments about relationism, absolutism, and particularly substantivalism. The current best arguments in favor of substantivalism are shown to be flawed, with the exception of the argument from inertial and metrical structure; and on this issue, it is shown that both relationism and substantivalism need to argue for modifications of GTR (restriction of its models to those with certain features) in order to have a non-trivial explanation of inertial and metrical structure. For relationists, a Machian account of the origin of inertia in some models of GTR is required. Chapter 4 demonstrates that such a Machian account is equivalent to the demand for a truly general relativity of motion. Chapter 5 explores the history of Einstein's commitment to Mach's ideas in his work on GTR. Through an examination of the history of Einstein's attempts to impose Machian constraints on the models of General Relativity, further insight into the nature of this problem is obtained, as are reasons to believe that the project is by no means

  18. Discrete Hamiltonian for general relativity

    NASA Astrophysics Data System (ADS)

    Ziprick, Jonathan; Gegenberg, Jack

    2016-02-01

    Beginning from the Ashtekar formulation of general relativity, we derive a physical Hamiltonian written in terms of (classical) loop gravity variables. This is done by defining the gravitational fields within a complex of three-dimensional cells and imposing that curvature and torsion vanish within each cell. The resulting theory is holographic, with the bulk dynamics being captured completely by degrees of freedom living on cell boundaries. Quantization is readily obtainable by existing methods.

  19. Sgr A* and general relativity

    NASA Astrophysics Data System (ADS)

    Johannsen, Tim

    2016-06-01

    General relativity has been widely tested in weak gravitational fields but still stands largely untested in the strong-field regime. According to the no-hair theorem, black holes in general relativity depend only on their masses and spins and are described by the Kerr metric. Mass and spin are the first two multipole moments of the Kerr spacetime and completely determine all higher-order moments. The no-hair theorem and, hence, general relativity can be tested by measuring potential deviations from the Kerr metric affecting such higher-order moments. Sagittarius A* (Sgr A*), the supermassive black hole at the center of the Milky Way, is a prime target for precision tests of general relativity with several experiments across the electromagnetic spectrum. First, near-infrared (NIR) monitoring of stars orbiting around Sgr A* with current and new instruments is expected to resolve their orbital precessions. Second, timing observations of radio pulsars near the Galactic center may detect characteristic residuals induced by the spin and quadrupole moment of Sgr A*. Third, the event horizon telescope, a global network of mm and sub-mm telescopes, aims to study Sgr A* on horizon scales and to image the silhouette of its shadow cast against the surrounding accretion flow using very-long baseline interferometric (VLBI) techniques. Both NIR and VLBI observations may also detect quasiperiodic variability of the emission from the accretion flow of Sgr A*. In this review, I discuss our current understanding of the spacetime of Sgr A* and the prospects of NIR, timing, and VLBI observations to test its Kerr nature in the near future.

  20. Results from Numerical General Relativity

    NASA Technical Reports Server (NTRS)

    Baker, John G.

    2011-01-01

    For several years numerical simulations have been revealing the details of general relativity's predictions for the dynamical interactions of merging black holes. I will review what has been learned of the rich phenomenology of these mergers and the resulting gravitational wave signatures. These wave forms provide a potentially observable record of the powerful astronomical events, a central target of gravitational wave astronomy. Asymmetric radiation can produce a thrust on the system which may accelerate the single black hole resulting from the merger to high relative velocity.

  1. Gravitation. [Book on general relativity

    NASA Technical Reports Server (NTRS)

    Misner, C. W.; Thorne, K. S.; Wheeler, J. A.

    1973-01-01

    This textbook on gravitation physics (Einstein's general relativity or geometrodynamics) is designed for a rigorous full-year course at the graduate level. The material is presented in two parallel tracks in an attempt to divide key physical ideas from more complex enrichment material to be selected at the discretion of the reader or teacher. The full book is intended to provide competence relative to the laws of physics in flat space-time, Einstein's geometric framework for physics, applications with pulsars and neutron stars, cosmology, the Schwarzschild geometry and gravitational collapse, gravitational waves, experimental tests of Einstein's theory, and mathematical concepts of differential geometry.

  2. Exposure of the general population to gasoline.

    PubMed Central

    Akland, G G

    1993-01-01

    This paper summarizes the currently available information on gasoline exposure to the general population. In general, the largest contribution to the time weighted exposures results from exposures while indoors, which are influenced by the outside air, indoor sources, and attached garages. Personal activities, including refueling and commuting, contribute significantly higher exposures but last for only a small portion of the 24-hr time weighted average. The highest exposed group includes those individuals living near large service stations and those with contaminated water supplies. PMID:8020446

  3. Reports of work related musculoskeletal injury among home care service workers compared with nursery school workers and the general population of employed women in Sweden.

    PubMed Central

    Ono, Y; Lagerström, M; Hagberg, M; Lindén, A; Malker, B

    1995-01-01

    OBJECTIVES--To describe the nationwide occurrence of work related musculoskeletal injuries among all home care service workers in Sweden, and to identify relative risks and risk factors of the injuries. METHODS--The study was based on work related injuries reported to the Swedish occupational injury information system in 1990-1. The work related musculoskeletal injuries were divided into overexertion accidents and musculoskeletal diseases. The incidence of the injuries in female home care service workers was compared with those in nursery school workers and all other employed women in Sweden. RESULTS--In home care service workers, the annual incidence of injury from overexertion accidents and musculoskeletal diseases were 19.2 and 15.1 per 1000 workers, respectively, which was higher than those in nursery school workers and all employed women in Sweden. For five injury locations including the back, all the age standardised relative risks (SRR) of overexertion accidents exceeded 4.0, and most of those for musculoskeletal diseases were 1.5 or more in home care service workers compared with all other employed women in Sweden. Total duration of sick leave due to overexertion accidents was 7.7 times, and musculoskeletal diseases 3.5 times, longer than in nursery school workers. National loss due to sick leave resulting from only musculoskeletal injuries in home care service workers was about 8.2% of the total work related sick leave in all employed women in Sweden, although the number of home care service workers represented only some 5% of this population. Lifting other people was most frequently reported as the main risk cause of overexertion accidents in both kinds of workers. CONCLUSIONS--The results support the hypothesis that home care service workers have higher annual injury incidence of musculoskeletal injuries than nursery school workers due to physically stressful tasks that are far less common in nursery school workers. PMID:7489060

  4. Friction Forces in General Relativity

    NASA Astrophysics Data System (ADS)

    Bini, D.; Gregoris, D.; Rosquist, K.

    2015-01-01

    Friction forces play an important role in a wide class of phenomena both in the contexts of classical mechanics and general relativity. This paper discusses the Poynting-Robertson approach to the description of the motion of a massive test particle inside a perfect fluid undergoing dissipative effects in curved space. Specific cases of motions 1) inside a photon gas near a Schwarzschild black hole; 2) inside a photon gas in the Tolman metric are then discussed with applications to models of accretion disks of a black hole and to motion inside a static radiation dominated Universe.

  5. [Some general considerations concerning Cuba's population policies].

    PubMed

    Aldana Martinez, L

    1978-01-01

    The policies developed in Cuba after the revolution that influenced population were primarily intended to alter basic structures hindering social and economic development rather than to affect population growth. Fertility has declined rapidly from 35.1/1000 in 1963 to a preliminary figure of 19.8/1000 in 1977, and interprovincial differences have significantly lessened. Factors influencing the decline include the increased participation of women in economic activities, improved access to contraception, the higher cultural level of couples and especially women made possible through adult education, and increased urbanization following the agrarian reform. Infant mortality declined from about 80/1000 live births in the late 1950s to 24.6/1000 live births in 1977, while mortality for 1-4 year olds is now 1.1/1000. Maternal mortality declined from 10.7/10,000 live births in 1965 to 4.6 in 1976. Expectation of life at birth was 70 years for both sexes in 1976. The most significant factors in the mortality decline appear to have been general improvements in material standards and the disappearance of nutritional deficiencies in children and mothers, creation of the National Health System which offers free health care nationwide, and improved educational levels. By the beginning of the century 40% of the urban population resided in places with over 2000 inhabitants. In 1953 the proportion was 51.4% and Havana contained 23% of the national population. The policy of the Revolution has been to exploit the natural resources of the entire country and to reform agriculture and livestock raising. The growth rate of the urban population between 1953 and 1970 of 3.1% was only slightly higher than the growth rate of 2.19% of the entire country. Havana grew by only 2.2% during the same time, and by only 1.3% between 1971-74. Intermediate cities increased their share of the total population from 10.6% in 1958 to 17.3% in 1970. Government programs to orient migration toward

  6. A Generalized Detailed Balance Relation

    NASA Astrophysics Data System (ADS)

    Ruelle, David

    2016-06-01

    Given a system M in a thermal bath we obtain a generalized detailed balance relation for the ratio r=π _τ (K→ J)/π _τ (J→ K) of the transition probabilities M:J→ K and M:K→ J in time τ . We assume an active bath, containing solute molecules in metastable states. These molecules may react with M and the transition J→ K occurs through different channels α involving different reactions with the bath. We find that r=sum p^α r^α , where p^α is the probability that channel α occurs, and r^α depends on the amount of heat (more precisely enthalpy) released to the bath in channel α.

  7. Spacecraft Tests of General Relativity

    NASA Technical Reports Server (NTRS)

    Anderson, John D.

    1997-01-01

    Current spacecraft tests of general relativity depend on coherent radio tracking referred to atomic frequency standards at the ground stations. This paper addresses the possibility of improved tests using essentially the current system, but with the added possibility of a space-borne atomic clock. Outside of the obvious measurement of the gravitational frequency shift of the spacecraft clock, a successor to the suborbital flight of a Scout D rocket in 1976 (GP-A Project), other metric tests would benefit most directly by a possible improved sensitivity for the reduced coherent data. For purposes of illustration, two possible missions are discussed. The first is a highly eccentric Earth orbiter, and the second a solar-conjunction experiment to measure the Shapiro time delay using coherent Doppler data instead of the conventional ranging modulation.

  8. A Generalized Detailed Balance Relation

    NASA Astrophysics Data System (ADS)

    Ruelle, David

    2016-08-01

    Given a system M in a thermal bath we obtain a generalized detailed balance relation for the ratio r=π _τ (K→ J)/π _τ (J→ K) of the transition probabilities M:J→ K and M:K→ J in time τ . We assume an active bath, containing solute molecules in metastable states. These molecules may react with M and the transition J→ K occurs through different channels α involving different reactions with the bath. We find that r=sum p^α r^α , where p^α is the probability that channel α occurs, and r^α depends on the amount of heat (more precisely enthalpy) released to the bath in channel α.

  9. Oral hygiene status in a general population of Iran, 2011: a key lifestyle marker in relation to common risk factors of non-communicable diseases

    PubMed Central

    Asgari, Fereshteh; Majidi, Azam; Koohpayehzadeh, Jalil; Etemad, Koorosh; Rafei, Ali

    2015-01-01

    Background: To estimate Oral Hygiene (OH) status in the Iranian population in 2011, and to determine the influence of socio-economic characteristics on OH, and its interrelation with common risk factors of Non-Communicable Diseases (NCDs). Methods: Data including a total of 12,105 individuals aged 6-70 years were obtained from the sixth round of the surveys of NCDs risk factors in Iran. OH was recorded through a structured questionnaire measuring daily frequencies of tooth brushing and dental flossing. Descriptive analyses were performed on demographic characteristics in the complex sample survey setting. We also employed weighted binary logistic regression to compute Odds Ratio (OR) as a measure of association between the response and explanatory factors. Furthermore, to construct an asset index, we utilized Principal Component Analysis (PCA). Results: The percentage with minimum recommended daily OH practices was 3.7% among men and 7.7% among women (OR= 2.3; P< 0.001). Urban citizens were more likely to have their teeth cleaned compared to rural people (OR= 2.8; P< 0.001). For both genders, a relatively better condition was observed in the 25–34 age group (male: 5.6%; female: 10.3%). In addition, OH status improved significantly by increase in both level of education (P< 0.001) and economic status (P< 0.001). There were also apparent associations between self-care practices and specific behavioral risk factors, though the correlation with dietary habits and tobacco use could be largely explained by socio-economic factors. Conclusion: OH situation in Iran calls for urgent need to assign proper interventions and strategies toward raising public awareness and reducing disparities in access to health facilities. PMID:26029893

  10. General Relativity and Gravitation, 1989

    NASA Astrophysics Data System (ADS)

    Ashby, Neil; Bartlett, David F.; Wyss, Walker

    2005-10-01

    Part I. Classical Relativity and Gravitation Theory: 1. Global properties of exact solutions H. Friedrich; 2. Numerical relativity T. Nakamura; 3. How fast can a pulsar spin? J. L. Friedman; 4. Colliding waves in general relativity V. Ferrari; Part II. Relativistic Astrophysics, Early Universe, and Classical Cosmology: 5. Observations of cosmic microwave radiation R. B. Partridge; 6. Cosmic microwave background radiation (theory) M. Panek; 7. Inflation and quantum cosmology A. D. Linde; 8. Observations of lensing B. Fort; 9. Gravitational lenses: theory and interpretation R. Blandford; Part III. Experimental Gravitation and Gravitational Waves: 10. Solar system tests of GR: recent results and present plans I. Shapiro; 11. Laser interferometer detectors R. Weiss; 12. Resonant bar gravitational wave experiments G. Pizzella; 13. A non-inverse square law test E. Adelberger; Part IV. Quantum Gravity, Superstrings, Quantum Cosmology: 14. Cosmic strings B. Unruh; 15. String theory as a quantum theory of gravity G. Horowitz; 16. Progress in quantum cosmology J. B. Hartle; 17. Self-duality, quantum gravity, Wilson loops and all that A. V. Ashtekar; Part V. Summary Talk: 18. GR-12 Conference summary J. Ehlers II; Part VI. Reports on Workshops/Symposia: 19. Exact solutions and exact properties of Einstein equations V. Moncrieff; 20. Spinors, twistors and complex methods N. Woodhouse; 21. Alternative gravity theories M. Francaviglia; 22. Asymptotia, singularities and global structure B. G. Schmidt; 23. Radiative spacetimes and approximation methods T. Damour; 24. Algebraic computing M. MacCallum; 25. Numerical relativity J. Centrella; 26. Mathematical cosmology J. Wainwright; 27. The early universe M. Turner; 28. Relativistic astrophysics M. Abramowitz; 29. Astrophysical and observational cosmology B. Carr; 30. Solar system and pulsar tests of gravitation R. Hellings; 31. Earth-based gravitational experiments J. Faller; 32. Resonant bar and microwave gravitational wave

  11. General Relativity and Gravitation, 1989

    NASA Astrophysics Data System (ADS)

    Ashby, Neil; Bartlett, David F.; Wyss, Walker

    1990-11-01

    Part I. Classical Relativity and Gravitation Theory: 1. Global properties of exact solutions H. Friedrich; 2. Numerical relativity T. Nakamura; 3. How fast can a pulsar spin? J. L. Friedman; 4. Colliding waves in general relativity V. Ferrari; Part II. Relativistic Astrophysics, Early Universe, and Classical Cosmology: 5. Observations of cosmic microwave radiation R. B. Partridge; 6. Cosmic microwave background radiation (theory) M. Panek; 7. Inflation and quantum cosmology A. D. Linde; 8. Observations of lensing B. Fort; 9. Gravitational lenses: theory and interpretation R. Blandford; Part III. Experimental Gravitation and Gravitational Waves: 10. Solar system tests of GR: recent results and present plans I. Shapiro; 11. Laser interferometer detectors R. Weiss; 12. Resonant bar gravitational wave experiments G. Pizzella; 13. A non-inverse square law test E. Adelberger; Part IV. Quantum Gravity, Superstrings, Quantum Cosmology: 14. Cosmic strings B. Unruh; 15. String theory as a quantum theory of gravity G. Horowitz; 16. Progress in quantum cosmology J. B. Hartle; 17. Self-duality, quantum gravity, Wilson loops and all that A. V. Ashtekar; Part V. Summary Talk: 18. GR-12 Conference summary J. Ehlers II; Part VI. Reports on Workshops/Symposia: 19. Exact solutions and exact properties of Einstein equations V. Moncrieff; 20. Spinors, twistors and complex methods N. Woodhouse; 21. Alternative gravity theories M. Francaviglia; 22. Asymptotia, singularities and global structure B. G. Schmidt; 23. Radiative spacetimes and approximation methods T. Damour; 24. Algebraic computing M. MacCallum; 25. Numerical relativity J. Centrella; 26. Mathematical cosmology J. Wainwright; 27. The early universe M. Turner; 28. Relativistic astrophysics M. Abramowitz; 29. Astrophysical and observational cosmology B. Carr; 30. Solar system and pulsar tests of gravitation R. Hellings; 31. Earth-based gravitational experiments J. Faller; 32. Resonant bar and microwave gravitational wave

  12. Association between Body Mass Index and Health-Related Quality of Life: The "Obesity Paradox" in 21,218 Adults of the Chinese General Population

    PubMed Central

    Zhu, Yanbo; Wang, Qi; Pang, Guoming; Lin, Lin; Origasa, Hideki; Wang, Yangyang; Di, Jie; Shi, Mai; Fan, Chunpok; Shi, Huimei

    2015-01-01

    Background There was no consistent recognition of the association between high or low body mass index (BMI) and health related quality of life (HRQL). The aim of this research was to study the association between BMI and HRQL in Chinese adults, and to further explore the stability of that association in the subgroup analysis stratified by status of chronic conditions. Methods A total of 21,218 adults aged 18 and older were classified as underweight, normal weight, overweight, class I obese, and class II obese based on their BMI. HRQL was measured by the SF-36 Health Survey. The independent impact of each BMI category on HRQL was examined through standard least squares regression by comparing the difference of SF-36 scores and the minimum clinically important differences (MCID), which was defined as 3 points. Results Compared to the normal weight, the class I obese was significantly associated with better HRQL scores in the mental component summary (MCS) (75.1 vs. 73.4, P<0.001). The underweight had the lowest score in both the physical components summary (PCS) (75.4 vs. 77.5, P<0.001) and mental components summary (MCS) (71.8 vs. 73.4, P<0.001). For the MCID, the HRQL score was reduced by more than 3 points in the physical functioning for the class II obese (D=-3.43) and the general health for the underweight (D=-3.71). Stratified analyses showed a similar result in the health subjects and chronic conditions, and it was significant in the chronic conditions. Conclusions The class I obese showed the best HRQL, especially in the mental domain. The worst HRQL was found in the underweight. The class II obese reduced HRQL in the physical functioning only. “Obesity paradox” was more obvious in the participants with chronic conditions. PMID:26087128

  13. General relativity in Newtonian form

    NASA Astrophysics Data System (ADS)

    Gautreau, Ronald

    1990-06-01

    It is shown how the use of coordinates where time is measured with clocks moving radially in a spherically symmetric gravitational field leads to general relativistic dynamical expressions that are exactly identical to corresponding expressions in Newtonian theory. The general formalism is developed for the case where the stress-energy tensor is that of a perfect fluid. Expressions like the Newtonian inverse square gravitational law, the Newtonian equation of continuity for fluid flow, Newtonian conservation of energy, etc., follow quite naturally from the fully-fledged exact general relativistic equations. Specific examples involving cosmology and gravitational collapse are given.

  14. On superpotentials in general relativity

    NASA Astrophysics Data System (ADS)

    Stolín, Oldřich; Novotný, Jan

    2001-10-01

    It is shown that the Einstein—Freud, Landau—Lifshitz and Møller tetrad super-potentials represent special cases of a more general construction. The tetrad version of the Landau—Lifshitz superpotential is derived.

  15. Chronic Disease in a General Adult Population

    PubMed Central

    Lohr, Kathleen N.; Kamberg, Caren J.; Goldberg, George A.; Brook, Robert H.; Keeler, Emmett B.; Calabro, Thomas A.

    1986-01-01

    Using questionnaire and physical screening examination data for a general population of 4,962 adults aged 18 to 61 years enrolled in the Rand Health Insurance Experiment, we calculated the prevalence of 13 chronic illnesses and assessed disease impact. Low-income men had a significantly higher prevalence of anemia, chronic airway disease and hearing impairment than their high-income counterparts, low-income women a higher prevalence of congestive heart failure, diabetes mellitus, hypertension, hearing impairment and vision impairment. Of our sample, 30% had one chronic condition and 16% had two or more. Several significant pairs or “clusters” of chronic illnesses were found. With few exceptions (diabetes, hypertension), the use of physician care in the previous year for a specific condition tended to be low. Disease impact (worry, activity restriction) was widespread but mild. Persons with angina, congestive heart failure, mild chronic joint disorders and peptic ulcer disease reported a greater impact than persons with other illnesses. PMID:3788141

  16. Fourth order deformed general relativity

    NASA Astrophysics Data System (ADS)

    Cuttell, Peter D.; Sakellariadou, Mairi

    2014-11-01

    Whenever the condition of anomaly freedom is imposed within the framework of effective approaches to loop quantum cosmology, one seems to conclude that a deformation of general covariance is required. Here, starting from a general deformation we regain an effective gravitational Lagrangian including terms up to fourth order in extrinsic curvature. We subsequently constrain the form of the corrections for the homogeneous case, and then investigate the conditions for the occurrence of a big bounce and the realization of an inflationary era, in the presence of a perfect fluid or scalar field.

  17. Uniform acceleration in general relativity

    NASA Astrophysics Data System (ADS)

    Friedman, Yaakov; Scarr, Tzvi

    2015-10-01

    We extend de la Fuente and Romero's (Gen Relativ Gravit 47:33, 2015) defining equation for uniform acceleration in a general curved spacetime from linear acceleration to the full Lorentz covariant uniform acceleration. In a flat spacetime background, we have explicit solutions. We use generalized Fermi-Walker transport to parallel transport the Frenet basis along the trajectory. In flat spacetime, we obtain velocity and acceleration transformations from a uniformly accelerated system to an inertial system. We obtain the time dilation between accelerated clocks. We apply our acceleration transformations to the motion of a charged particle in a constant electromagnetic field and recover the Lorentz-Abraham-Dirac equation.

  18. Adalimumab improves health-related quality of life in patients with moderate to severe plaque psoriasis compared with the United States general population norms: Results from a randomized, controlled Phase III study

    PubMed Central

    Revicki, Dennis A; Menter, Alan; Feldman, Steven; Kimel, Miriam; Harnam, Neesha; Willian, Mary K

    2008-01-01

    Objective To evaluate the impact of adalimumab on health-related quality of life (HRQOL) for patients with moderate to severe plaque psoriasis. Background Psoriasis is a chronic, inflammatory, immune-mediated disease that has a significant impact on patients' HRQOL. Adalimumab is a fully human monoclonal antibody that blocks tumor necrosis factor, a pro-inflammatory cytokine, and is effective and well-tolerated for patients with moderate to severe psoriasis. Methods Data were obtained for a secondary analysis of patients in a randomized, controlled Phase III trial evaluating the effect of adalimumab in patients with psoriasis (N = 1,205). Patients with moderate to severe psoriasis were randomized in a 2:1 ratio to adalimumab 80 mg (two 40 mg injections administered subcutaneously at baseline followed by one 40 mg injection every other week from Week 1 to Week 15) or placebo. Short Form-36 (SF-36) Health Survey scores of psoriasis patients were used to assess HRQOL and were compared with United States (US) population norms at baseline and Week 16. Results Baseline Physical Component Summary (PCS) scores for the placebo and adalimumab groups were similar to the general US population. Baseline mean Mental Component Summary (MCS) scores were significantly lower for the adalimumab and placebo groups compared with the general population (47.4, 47.7, and 50.8 points, respectively; p < 0.0001). PCS scores at Week 16 for patients receiving adalimumab had improved and were significantly greater than scores for the general US population (52.7 vs 48.9; p < 0.001). Compared with the general US population, MCS scores at Week 16 were similar for patients receiving adalimumab (51.2 vs 50.8; p = 1.000) and lower for patients receiving placebo (50.8 vs 48.7; p < 0.0001). Conclusion Psoriasis has a broad impact on patient functioning and well-being. Improvement in skin lesions and joint symptoms associated with adalimumab treatment was accompanied by improvements in HRQOL to levels

  19. Action principle for the generalized harmonic formulation of general relativity

    SciTech Connect

    Brown, J. David

    2011-10-15

    An action principle for the generalized harmonic formulation of general relativity is presented. The action is a functional of the spacetime metric and the gauge source vector. An action principle for the Z4 formulation of general relativity has been proposed recently by Bona, Bona-Casas, and Palenzuela. The relationship between the generalized harmonic action and the Bona, Bona-Casas, and Palenzuela action is discussed in detail.

  20. Quantifying tone deafness in the general population.

    PubMed

    Sloboda, John A; Wise, Karen J; Peretz, Isabelle

    2005-12-01

    the general population, whose purpose is to discriminate "true" from "false" amusics. Such discrimination is essential to achieve a better understanding of the variety of causes of low musical achievement. PMID:16597772

  1. Quasilocal mass in general relativity.

    PubMed

    Wang, Mu-Tao; Yau, Shing-Tung

    2009-01-16

    There have been many attempts to define the notion of quasilocal mass for a spacelike two surface in spacetime by the Hamilton-Jacobi analysis. The essential difficulty in this approach is to identify the right choice of the background configuration to be subtracted from the physical Hamiltonian. Quasilocal mass should be non-negative for surfaces in general spacetime and zero for surfaces in flat spacetime. In this Letter, we propose a new definition of gauge-independent quasilocal mass and prove that it has the desired properties. PMID:19257261

  2. General relativity and satellite orbits

    NASA Technical Reports Server (NTRS)

    Rubincam, D. P.

    1975-01-01

    The general relativistic correction to the position of a satellite is found by retaining Newtonian physics for an observer on the satellite and introducing a potential. The potential is expanded in terms of the Keplerian elements of the orbit and substituted in Lagrange's equations. Integration of the equations shows that a typical earth satellite with small orbital eccentricity is displaced by about 17 cm. from its unperturbed position after a single orbit, while the periodic displacement over the orbit reaches a maximum of about 3 cm. The moon is displaced by about the same amounts. Application of the equations to Mercury gives a total displacement of about 58 km. after one orbit and a maximum periodic displacement of about 12 km.

  3. Screening and triage of intrauterine growth restriction (IUGR) in general population and high risk pregnancies: a systematic review with a focus on reduction of IUGR related stillbirths

    PubMed Central

    2011-01-01

    Background There is a strong association between stillbirth and fetal growth restriction. Early detection and management of IUGR can lead to reduce related morbidity and mortality. In this paper we have reviewed effectiveness of fetal movement monitoring and Doppler velocimetry for the detection and surveillance of high risk pregnancies and the effect of this on prevention of stillbirths. We have also reviewed effect of maternal body mass index (BMI) screening, symphysial-fundal height measurement and targeted ultrasound in detection and triage of IUGR in the community. Methods We systematically reviewed all published literature to identify studies related to our interventions. We searched PubMed, Cochrane Library, and all World Health Organization Regional Databases and included publications in any language. Quality of available evidence was assessed using GRADE criteria. Recommendations were made for the Lives Saved Tool (LiST) based on rules developed by the Child Health Epidemiology Group. Given the paucity of evidence related to the effect of detection and management of IUGR on stillbirths, we undertook Delphi based evaluation from experts in the field. Results There was insufficient evidence to recommend against or in favor of routine use of fetal movement monitoring for fetal well being. (1) Detection and triage of IUGR with the help of (1a) maternal BMI screening, (1b) symphysial-fundal height measurement and (1c) targeted ultrasound can be an effective method of reducing IUGR related perinatal morbidity and mortality. Pooled results from sixteen studies shows that Doppler velocimetry of umbilical and fetal arteries in ‘high risk’ pregnancies, coupled with the appropriate intervention, can reduce perinatal mortality by 29 % [RR 0.71, 95 % CI 0.52-0.98]. Pooled results for impact on stillbirth showed a reduction of 35 % [RR 0.65, 95 % CI 0.41-1.04]; however, the results did not reach the conventional limits of statistical significance. This intervention

  4. Pulsar timing and general relativity

    NASA Technical Reports Server (NTRS)

    Backer, D. C.; Hellings, R. W.

    1986-01-01

    Techniques are described for accounting for relativistic effects in the analysis of pulsar signals. Design features of instrumentation used to achieve millisecond accuracy in the signal measurements are discussed. The accuracy of the data permits modeling the pulsar physical characteristics from the natural glitches in the emissions. Relativistic corrections are defined for adjusting for differences between the pulsar motion in its spacetime coordinate system relative to the terrestrial coordinate system, the earth's motion, and the gravitational potentials of solar system bodies. Modifications of the model to allow for a binary pulsar system are outlined, including treatment of the system as a point mass. Finally, a quadrupole model is presented for gravitational radiation and techniques are defined for using pulsars in the search for gravitational waves.

  5. Age-related changes in the distributions of depressive symptom items in the general population: a cross-sectional study using the exponential distribution model

    PubMed Central

    Kawasaki, Yohei; Ide, Kazuki; Yamada, Hiroshi; Furukawa, Toshiaki A.; Ono, Yutaka

    2016-01-01

    Background. Previous research has reported inconsistent evidence of the trajectory of depressive symptoms across the adult lifespan. We investigated how the distributions of each item score change with age and determined whether the trajectory of depressive symptoms varied with the scoring methods of the questionnaire. Methods. We analyzed data collected from 21,040 subjects who participated in the national survey in Japan. Depressive symptoms were assessed using the Center for Epidemiologic Studies Depression Scale (CES-D). The CES-D has 20 items, each of which is scored in four grades of “rarely,” “some,” “much,” and “most of the time.” We used the exponential distribution model which fits the distributions of 16 negative symptom items of CES-D, with the probabilities of “some,” “much,” “most,” and “rarely” expressed as P, Pr, Pr2, and 1 − P × (r2 + r + 1). Results. The distributions of the responses to 16 negative symptom items followed the common exponential model across all age groups. The mean of the estimated parameter r of 16 negative items showed a U-shape pattern, being high during 12–29 years, remaining low during 30–50 years, and then increasing again over 60 years. The trajectory of depressive symptom scores simulating the binary method was different from that of the empirical scores using the Likert method. Conclusions. Our findings show that the increase in the depressive symptoms score during older age is based on the increase of the parameter r. The differences in the scoring method may contribute to the different age-related patterns across the adult lifespan. PMID:26788427

  6. Age-related changes in the distributions of depressive symptom items in the general population: a cross-sectional study using the exponential distribution model.

    PubMed

    Tomitaka, Shinichiro; Kawasaki, Yohei; Ide, Kazuki; Yamada, Hiroshi; Furukawa, Toshiaki A; Ono, Yutaka

    2016-01-01

    Background. Previous research has reported inconsistent evidence of the trajectory of depressive symptoms across the adult lifespan. We investigated how the distributions of each item score change with age and determined whether the trajectory of depressive symptoms varied with the scoring methods of the questionnaire. Methods. We analyzed data collected from 21,040 subjects who participated in the national survey in Japan. Depressive symptoms were assessed using the Center for Epidemiologic Studies Depression Scale (CES-D). The CES-D has 20 items, each of which is scored in four grades of "rarely," "some," "much," and "most of the time." We used the exponential distribution model which fits the distributions of 16 negative symptom items of CES-D, with the probabilities of "some," "much," "most," and "rarely" expressed as P, Pr, Pr (2), and 1 - P × (r (2) + r + 1). Results. The distributions of the responses to 16 negative symptom items followed the common exponential model across all age groups. The mean of the estimated parameter r of 16 negative items showed a U-shape pattern, being high during 12-29 years, remaining low during 30-50 years, and then increasing again over 60 years. The trajectory of depressive symptom scores simulating the binary method was different from that of the empirical scores using the Likert method. Conclusions. Our findings show that the increase in the depressive symptoms score during older age is based on the increase of the parameter r. The differences in the scoring method may contribute to the different age-related patterns across the adult lifespan. PMID:26788427

  7. In Pursuit of General Behavioral Relations.

    ERIC Educational Resources Information Center

    Mace, F. Charles

    1996-01-01

    Discusses behavioral momentum and the general behavioral relation between the persistence of behavior and the rate of reinforcement obtained in a given situation. Strategies for establishing the generality of behavioral relations are reviewed, followed by a brief summary of evidence for the generality of behavioral momentum. (Author/CR)

  8. Nightmares: Risk Factors Among the Finnish General Adult Population

    PubMed Central

    Sandman, Nils; Valli, Katja; Kronholm, Erkki; Revonsuo, Antti; Laatikainen, Tiina; Paunio, Tiina

    2015-01-01

    Study Objectives: To identify risk factors for experiencing nightmares among the Finnish general adult population. The study aimed to both test whether previously reported correlates of frequent nightmares could be reproduced in a large population sample and to explore previously unreported associations. Design: Two independent cross-sectional population surveys of the National FINRISK Study. Setting: Age- and sex-stratified random samples of the Finnish population in 2007 and 2012. Participants: A total of 13,922 participants (6,515 men and 7,407 women) aged 25–74 y. Interventions: N/A. Measurements and results: Nightmare frequency as well as several items related to socioeconomic status, sleep, mental well-being, life satisfaction, alcohol use, medication, and physical well-being were recorded with a questionnaire. In multinomial logistic regression analysis, a depression-related negative attitude toward the self (odds ratio [OR] 1.32 per 1-point increase), insomnia (OR 6.90), and exhaustion and fatigue (OR 6.86) were the strongest risk factors for experiencing frequent nightmares (P < 0.001 for all). Sex, age, a self-reported impaired ability to work, low life satisfaction, the use of antidepressants or hypnotics, and frequent heavy use of alcohol were also strongly associated with frequent nightmares (P < 0.001 for all). Conclusions: Symptoms of depression and insomnia were the strongest predictors of frequent nightmares in this dataset. Additionally, a wide variety of factors related to psychological and physical well-being were associated with nightmare frequency with modest effect sizes. Hence, nightmare frequency appears to have a strong connection with sleep and mood problems, but is also associated with a variety of measures of psychological and physical well-being. Citation: Sandman N, Valli K, Kronholm E, Revonsuo A, Laatikainen T, Paunio T. Nightmares: risk factors among the finnish general adult population. SLEEP 2015;38(4):507–514. PMID:25325474

  9. Social integration of juvenile amputees: comparison with a general population.

    PubMed

    Fernández, A; Revilla, C; Su, I-Ting; García, M

    2003-04-01

    The objective was to assess the social integration of juvenile amputees according to marital status, schooling and occupation, and to compare it with the population of Asturias, Spain. A retrospective study was carried out of the juvenile amputees registered from 1976 to 1999 at the Prosthetics Unit of the Asturias Central Hospital (n=281 amputees). The proportion of single women amongst the amputees was greater than in the population of Asturias (p<0.05). Amongst the male amputees, relative to the general population, there was a larger proportion of the group with primary studies (p<0.001) and a smaller proportion with secondary studies (p<0.001). At the higher level (university) there were no differences, either in men or in women. As regards occupation, amongst the amputees a larger number was found who were retired or unemployed (p<0.05 and p<0.001). In conclusion, juvenile amputees do not show differences compared to the general population with regard to their attendance at a higher or university level of education. However, if their social integration is considered through occupation, male amputees show a greater proportion of unemployment, which is a clear reflection of their handicap. PMID:12812323

  10. A general consumer-resource population model

    USGS Publications Warehouse

    Lafferty, Kevin D.; DeLeo, Giulio; Briggs, Cheryl J.; Dobson, Andrew P.; Gross, Thilo; Kuris, Armand M.

    2015-01-01

    Food-web dynamics arise from predator-prey, parasite-host, and herbivore-plant interactions. Models for such interactions include up to three consumer activity states (questing, attacking, consuming) and up to four resource response states (susceptible, exposed, ingested, resistant). Articulating these states into a general model allows for dissecting, comparing, and deriving consumer-resource models. We specify this general model for 11 generic consumer strategies that group mathematically into predators, parasites, and micropredators and then derive conditions for consumer success, including a universal saturating functional response. We further show how to use this framework to create simple models with a common mathematical lineage and transparent assumptions. Underlying assumptions, missing elements, and composite parameters are revealed when classic consumer-resource models are derived from the general model.

  11. General Information about AIDS-Related Lymphoma

    MedlinePlus

    ... AIDS-Related Lymphoma Treatment (PDQ®)–Patient Version General Information About AIDS-Related Lymphoma Go to Health Professional ... the PDQ Adult Treatment Editorial Board . Clinical Trial Information A clinical trial is a study to answer ...

  12. General Relativity in (1 + 1) Dimensions

    ERIC Educational Resources Information Center

    Boozer, A. D.

    2008-01-01

    We describe a theory of gravity in (1 + 1) dimensions that can be thought of as a toy model of general relativity. The theory should be a useful pedagogical tool, because it is mathematically much simpler than general relativity but shares much of the same conceptual structure; in particular, it gives a simple illustration of how gravity arises…

  13. Characteristics of the General Physics student population.

    NASA Astrophysics Data System (ADS)

    Hunt, Gary L.

    2006-12-01

    Are pre-medical students different than the other students in a General physics class? They often appear to be different, based on how often they seek help from the instructor or how nervous they are about 2 points on a lab report. But are these students different in a measurable characteristic? The purpose of this study is to better understand the characteristics of the students in the introductory physics classes. This is the first step toward improving the instruction. By better understanding the students the classroom, the organization and pedagogy can be adjusted to optimize student learning. The characteristics to be investigated during this study are: · student epistemological structure, · student attitudes, · science course preparation prior to this course, · study techniques used, · physics concepts gained during the class · performance in the class. The data will be analyzed to investigate differences between groups. The groups investigated will be major, gender, and traditional/nontraditional students.

  14. A General Framework for Relative Impact Indicators.

    ERIC Educational Resources Information Center

    Egghe, Leo; Rousseau, Ronald

    2003-01-01

    Discussion of the assessment and comparison of scientific journals, bibliometrics, and types of impact factors focuses on a general framework for the relative comparison of journal impact. Highlights include the relative impact of a journal within a set of journals, or meta-journal; and mathematical explorations of relative indicators. (Author/LRW)

  15. Recovering General Relativity from Massive Gravity

    SciTech Connect

    Babichev, E.; Deffayet, C.; Ziour, R.

    2009-11-13

    We obtain static, spherically symmetric, and asymptotically flat numerical solutions of massive gravity with a source. Those solutions show, for the first time explicitly, a recovery of the Schwarzschild solution of general relativity via the so-called Vainshtein mechanism.

  16. Einstein and General Relativity: Historical Perspectives.

    ERIC Educational Resources Information Center

    Chandrasekhar, S.

    1979-01-01

    This paper presented in the 1978 Oppenheimer Memorial Lecture at Los Alamos Scientific Laboratories on August 17, 1978, discusses Einstein's contributions to physics, in particular, his discovery of the general theory of relativity. (HM)

  17. Colorectal cancer screening of the general population in East Asia.

    PubMed

    Sano, Yasushi; Byeon, Jeong-Sik; Li, Xiao-Bo; Wong, Martin C S; Chiu, Han-Mo; Rerknimitr, Rungsun; Utsumi, Takahiro; Hattori, Santa; Sano, Wataru; Iwatate, Mineo; Chiu, Philip; Sung, Joseph

    2016-04-01

    In recent years, the incidence of colorectal cancer (CRC) has been increasing, and CRC has been becoming the major cause of cancer deaths in Asian countries. Therefore, an organized screening program to reduce CRC incidence and mortality is currently implemented in each country. In the present review, we summarize the current status and future perspectives of CRC screening of the general population in East Asian and South-East Asian countries. The fecal occult blood test is widely used for CRC screening in these countries, and its effectiveness in reducing CRC incidence and mortality has been demonstrated; however, the low participation rate in CRC screening programs is a problem to be solved in every country. Improvement in the public awareness of CRC and promotion of CRC screening by physicians will help to raise the participation rate and reduce the number of deaths caused by CRC. Regarding screening colonoscopy, several studies have recently demonstrated its effectiveness in reducing CRC incidence and mortality. However, at present, CRC screening colonoscopy is not adopted as a primary population-based screening tool because of staffing constraints in relation to large population sizes, increased medical costs, and potential adverse events (e.g. perforation and drug-induced anaphylaxis). Further study is required to consider colonoscopy as CRC screening that is established in Western countries. PMID:26595883

  18. A cross-sectional survey of experts’ opinions about the relative effectiveness of tobacco control strategies for the general population versus disadvantaged groups: what do we choose in the absence of evidence?

    PubMed Central

    2013-01-01

    Background There is a clear disparity in smoking rates according to social disadvantage. In the absence of sufficiently robust data regarding effective strategies for reducing smoking prevalence in disadvantaged populations, understanding the views of tobacco control experts can assist with funding decisions and research agendas. Methods A web-based cross-sectional survey was conducted with 192 respondents (response rate 65%) sampled from the Australian and New Zealand Tobacco Control Contacts list and a literature search. Respondents were asked to indicate whether a number of tobacco control strategies were perceived to be effective for each of: the general population; Aboriginal and Torres Strait Islander people; those with a low income; and people with a mental illness. Results A high proportion of respondents indicated that mass media and increased tobacco taxation (84% and 89% respectively) were effective for the general population. Significantly lower proportions reported these two strategies were effective for sub-populations, particularly Aboriginal and Torres Strait Islanders (58% and 63% respectively, p’s < .0001). Subsidised medication was the only strategy associated with a greater proportion of respondents perceiving it to be effective in disadvantaged sub-populations compared to the general population. Tailored quit programs and culturally relevant programs were nominated as additional effective strategies for disadvantaged populations. Conclusions Views about subsidised medications in particular, suggest the need for robust cost-effectiveness data relevant to disadvantaged groups to avoid wastage of scarce tobacco control resources. Strategies perceived to be effective for disadvantaged populations such as tailored or culturally relevant programs require rigorous evaluation so that potential adoption of these approaches is evidence-based. PMID:24314097

  19. Nonlinear SUSY General Relativity Theory and Significances

    NASA Astrophysics Data System (ADS)

    Shima, Kazunari; Tsuda, Motomu

    2012-02-01

    We show some interesting consequences of the nonliear supersymmetric general relativity theory(NLSUSYGR) on particle physics, cosmology and their relations. They may geiv new insights into the SUSY breaking mechanism, dark energy, dark matter and the low enegy superpartner particles which are compatible with the recent LHC data.

  20. Teaching General Relativity to the Layperson

    ERIC Educational Resources Information Center

    Egdall, Mark

    2009-01-01

    This paper describes a lay course on general relativity (GR) given at the Osher Lifelong Learning Institute at Florida International University. It is presented in six hour-and-a-half weekly sessions. Other courses offered by the author include special relativity (which precedes the course described here), quantum theory, and cosmology. Students…

  1. Black hole based tests of general relativity

    NASA Astrophysics Data System (ADS)

    Yagi, Kent; Stein, Leo C.

    2016-03-01

    General relativity has passed all solar system experiments and neutron star based tests, such as binary pulsar observations, with flying colors. A more exotic arena for testing general relativity is in systems that contain one or more black holes. Black holes are the most compact objects in the Universe, providing probes of the strongest-possible gravitational fields. We are motivated to study strong-field gravity since many theories give large deviations from general relativity only at large field strengths, while recovering the weak-field behavior. In this article, we review how one can probe general relativity and various alternative theories of gravity by using electromagnetic waves from a black hole with an accretion disk, and gravitational waves from black hole binaries. We first review model-independent ways of testing gravity with electromagnetic/gravitational waves from a black hole system. We then focus on selected examples of theories that extend general relativity in rather simple ways. Some important characteristics of general relativity include (but are not limited to) (i) only tensor gravitational degrees of freedom, (ii) the graviton is massless, (iii) no quadratic or higher curvatures in the action, and (iv) the theory is four-dimensional. Altering a characteristic leads to a different extension of general relativity: (i) scalar-tensor theories, (ii) massive gravity theories, (iii) quadratic gravity, and (iv) theories with large extra dimensions. Within each theory, we describe black hole solutions, their properties, and current and projected constraints on each theory using black hole based tests of gravity. We close this review by listing some of the open problems in model-independent tests and within each specific theory.

  2. General very special relativity in Finsler cosmology

    SciTech Connect

    Kouretsis, A. P.; Stathakopoulos, M.; Stavrinos, P. C.

    2009-05-15

    General very special relativity (GVSR) is the curved space-time of very special relativity (VSR) proposed by Cohen and Glashow. The geometry of general very special relativity possesses a line element of Finsler geometry introduced by Bogoslovsky. We calculate the Einstein field equations and derive a modified Friedmann-Robertson-Walker cosmology for an osculating Riemannian space. The Friedmann equation of motion leads to an explanation of the cosmological acceleration in terms of an alternative non-Lorentz invariant theory. A first order approach for a primordial-spurionic vector field introduced into the metric gives back an estimation of the energy evolution and inflation.

  3. General Relativity Theory: Recognition through Time

    NASA Astrophysics Data System (ADS)

    Alexandrov, A. N.; Vavilova, I. B.; Zhdanov, V. I.; Zhuk, A. I.; Kudrya, Yu. N.; Parnovsky, S. L.; Fedorova, E. V.; Yatskiv, Ya. S.

    2015-10-01

    The book provides an overview of the current state of the General Relativity Theory on the eve of its centennial. The authors describe briefly the basis of this theory, systematize experimental verifications and outline the main areas of its applications in astrophysics, cosmology and astrometry in the light of the last decade. For researchers and students specializing in the Relativity Theory as well as for anyone interested in Relativity Theory, relativistic astrophysics and cosmology.

  4. The detection rate of inspiral and quasi-normal modes of Population III binary black holes which can confirm or refute the general relativity in the strong gravity region

    NASA Astrophysics Data System (ADS)

    Kinugawa, Tomoya; Miyamoto, Akinobu; Kanda, Nobuyuki; Nakamura, Takashi

    2016-02-01

    Using our population synthesis code, we found that the typical chirp mass defined by (m1m2)3/5/(m1 + m2)1/5 of Population III (Pop III) binary black holes (BH-BHs) is ˜30 M⊙ with the total mass of ˜60 M⊙ so that the inspiral chirp signal as well as quasi-normal mode (QNM) of the merging black hole (BH) are interesting targets of KAGRA. The detection rate of the coalescing Pop III BH-BHs is ˜180 events yr- 1 (SFRp/(10-2.5 M⊙ yr-1 Mpc-3))([fb/(1 + fb)]/0.33)Errsys in our standard model, where SFRp, fb and Errsys are the peak value of the Pop III star formation rate, the binary fraction and the systematic error with Errsys = 1 for our standard model, respectively. To evaluate the robustness of chirp mass distribution and the range of Errsys, we examine the dependence of the results on the unknown parameters and the distribution functions in the population synthesis code. We found that the chirp mass has a peak at ˜30 M⊙ in most of parameters and distribution functions as well as Errsys ranges from 0.046 to 4. Therefore, the detection rate of the coalescing Pop III BH-BHs ranges about 8.3-720 events yr- 1(SFRp/(10- 2.5 M⊙ yr- 1 Mpc- 3))([fb/(1 + fb)]/0.33). The minimum rate corresponds to the worst model which we think unlikely so that unless (SFRp/(10- 2.5 M⊙ yr- 1 Mpc- 3))([fb/(1 + fb)]/0.33) ≪ 0.1, we expect the Pop III BH-BHs merger rate of at least one event per year by KAGRA. Nakano, Tanaka & Nakamura show that if signal-to-noise ratio (S/N) of QNM is larger than 35, we can confirm or refute the general relativity (GR) more than 5σ level. In our standard model, the detection rate of Pop III BH-BHs whose S/N is larger than 35 is 3.2 events yr- 1 (SFRp/(10- 2.5 M⊙ yr- 1 Mpc- 3))([fb/(1 + fb)]/0.33)Errsys. Thus, there is a good chance to check whether GR is correct or not in the strong gravity region.

  5. Worldwide Estimates Relative to Five Continental-Scale Populations

    PubMed Central

    Steele, Christopher D; Court, Denise Syndercombe; Balding, David J

    2014-01-01

    We estimate the population genetics parameter (also referred to as the fixation index) from short tandem repeat (STR) allele frequencies, comparing many worldwide human subpopulations at approximately the national level with continental-scale populations. is commonly used to measure population differentiation, and is important in forensic DNA analysis to account for remote shared ancestry between a suspect and an alternative source of the DNA. We estimate comparing subpopulations with a hypothetical ancestral population, which is the approach most widely used in population genetics, and also compare a subpopulation with a sampled reference population, which is more appropriate for forensic applications. Both estimation methods are likelihood-based, in which is related to the variance of the multinomial-Dirichlet distribution for allele counts. Overall, we find low values, with posterior 97.5 percentiles when comparing a subpopulation with the most appropriate population, and even for inter-population comparisons we find . These are much smaller than single nucleotide polymorphism-based inter-continental estimates, and are also about half the magnitude of STR-based estimates from population genetics surveys that focus on distinct ethnic groups rather than a general population. Our findings support the use of up to 3% in forensic calculations, which corresponds to some current practice. PMID:26460400

  6. Tests of general relativity using pulsars

    NASA Technical Reports Server (NTRS)

    Reichley, P. E.

    1971-01-01

    The arrival times of the pulses from each pulsar are measured by a cesium clock. The observations are all made at a frequency of 2388 MHz (12.5 cm wavelength) on a 26 m dish antenna. The effect of interstellar charged particles is a random one that increases the noise level on the arrival time measurements. The variation in clock rate is shown consisting of two effects: the time dilation effect of special relativity and the red shift effect of general relativity.

  7. Affine generalization of the Komar complex of general relativity

    NASA Astrophysics Data System (ADS)

    Mielke, Eckehard W.

    2001-02-01

    On the basis of the ``on shell'' Noether identities of the metric-affine gauge approach of gravity, an affine superpotential is derived which comprises the energy- and angular-momentum content of exact solutions. In the special case of general relativity (GR) or its teleparallel equivalent, the Komar or Freud complex, respectively, are recovered. Applying this to the spontaneously broken anti-de Sitter gauge model of McDowell and Mansouri with an induced Euler term automatically yields the correct mass and spin of the Kerr-AdS solution of GR with a (induced) cosmological constant without the factor two discrepancy of the Komar formula.

  8. Generating perfect fluid spheres in general relativity

    NASA Astrophysics Data System (ADS)

    Boonserm, Petarpa; Visser, Matt; Weinfurtner, Silke

    2005-06-01

    Ever since Karl Schwarzschild’s 1916 discovery of the spacetime geometry describing the interior of a particular idealized general relativistic star—a static spherically symmetric blob of fluid with position-independent density—the general relativity community has continued to devote considerable time and energy to understanding the general-relativistic static perfect fluid sphere. Over the last 90 years a tangle of specific perfect fluid spheres has been discovered, with most of these specific examples seemingly independent from each other. To bring some order to this collection, in this article we develop several new transformation theorems that map perfect fluid spheres into perfect fluid spheres. These transformation theorems sometimes lead to unexpected connections between previously known perfect fluid spheres, sometimes lead to new previously unknown perfect fluid spheres, and in general can be used to develop a systematic way of classifying the set of all perfect fluid spheres.

  9. Tests of General Relativity with GW150914.

    PubMed

    Abbott, B P; Abbott, R; Abbott, T D; Abernathy, M R; Acernese, F; Ackley, K; Adams, C; Adams, T; Addesso, P; Adhikari, R X; Adya, V B; Affeldt, C; Agathos, M; Agatsuma, K; Aggarwal, N; Aguiar, O D; Aiello, L; Ain, A; Ajith, P; Allen, B; Allocca, A; Altin, P A; Anderson, S B; Anderson, W G; Arai, K; Araya, M C; Arceneaux, C C; Areeda, J S; Arnaud, N; Arun, K G; Ascenzi, S; Ashton, G; Ast, M; Aston, S M; Astone, P; Aufmuth, P; Aulbert, C; Babak, S; Bacon, P; Bader, M K M; Baker, P T; Baldaccini, F; Ballardin, G; Ballmer, S W; Barayoga, J C; Barclay, S E; Barish, B C; Barker, D; Barone, F; Barr, B; Barsotti, L; Barsuglia, M; Barta, D; Bartlett, J; Bartos, I; Bassiri, R; Basti, A; Batch, J C; Baune, C; Bavigadda, V; Bazzan, M; Behnke, B; Bejger, M; Bell, A S; Bell, C J; Berger, B K; Bergman, J; Bergmann, G; Berry, C P L; Bersanetti, D; Bertolini, A; Betzwieser, J; Bhagwat, S; Bhandare, R; Bilenko, I A; Billingsley, G; Birch, J; Birney, R; Birnholtz, O; Biscans, S; Bisht, A; Bitossi, M; Biwer, C; Bizouard, M A; Blackburn, J K; Blair, C D; Blair, D G; Blair, R M; Bloemen, S; Bock, O; Bodiya, T P; Boer, M; Bogaert, G; Bogan, C; Bohe, A; Bojtos, P; Bond, C; Bondu, F; Bonnand, R; Boom, B A; Bork, R; Boschi, V; Bose, S; Bouffanais, Y; Bozzi, A; Bradaschia, C; Brady, P R; Braginsky, V B; Branchesi, M; Brau, J E; Briant, T; Brillet, A; Brinkmann, M; Brisson, V; Brockill, P; Brooks, A F; Brown, D A; Brown, D D; Brown, N M; Buchanan, C C; Buikema, A; Bulik, T; Bulten, H J; Buonanno, A; Buskulic, D; Buy, C; Byer, R L; Cadonati, L; Cagnoli, G; Cahillane, C; Calderón Bustillo, J; Callister, T; Calloni, E; Camp, J B; Cannon, K C; Cao, J; Capano, C D; Capocasa, E; Carbognani, F; Caride, S; Casanueva Diaz, J; Casentini, C; Caudill, S; Cavaglià, M; Cavalier, F; Cavalieri, R; Cella, G; Cepeda, C B; Cerboni Baiardi, L; Cerretani, G; Cesarini, E; Chakraborty, R; Chalermsongsak, T; Chamberlin, S J; Chan, M; Chao, S; Charlton, P; Chassande-Mottin, E; Chen, H Y; Chen, Y; Cheng, C; Chincarini, A; Chiummo, A; Cho, H S; Cho, M; Chow, J H; Christensen, N; Chu, Q; Chua, S; Chung, S; Ciani, G; Clara, F; Clark, J A; Cleva, F; Coccia, E; Cohadon, P-F; Colla, A; Collette, C G; Cominsky, L; Constancio, M; Conte, A; Conti, L; Cook, D; Corbitt, T R; Cornish, N; Corsi, A; Cortese, S; Costa, C A; Coughlin, M W; Coughlin, S B; Coulon, J-P; Countryman, S T; Couvares, P; Cowan, E E; Coward, D M; Cowart, M J; Coyne, D C; Coyne, R; Craig, K; Creighton, J D E; Cripe, J; Crowder, S G; Cumming, A; Cunningham, L; Cuoco, E; Dal Canton, T; Danilishin, S L; D'Antonio, S; Danzmann, K; Darman, N S; Dattilo, V; Dave, I; Daveloza, H P; Davier, M; Davies, G S; Daw, E J; Day, R; DeBra, D; Debreczeni, G; Degallaix, J; De Laurentis, M; Deléglise, S; Del Pozzo, W; Denker, T; Dent, T; Dereli, H; Dergachev, V; De Rosa, R; DeRosa, R T; DeSalvo, R; Dhurandhar, S; Díaz, M C; Di Fiore, L; Di Giovanni, M; Di Lieto, A; Di Pace, S; Di Palma, I; Di Virgilio, A; Dojcinoski, G; Dolique, V; Donovan, F; Dooley, K L; Doravari, S; Douglas, R; Downes, T P; Drago, M; Drever, R W P; Driggers, J C; Du, Z; Ducrot, M; Dwyer, S E; Edo, T B; Edwards, M C; Effler, A; Eggenstein, H-B; Ehrens, P; Eichholz, J; Eikenberry, S S; Engels, W; Essick, R C; Etzel, T; Evans, M; Evans, T M; Everett, R; Factourovich, M; Fafone, V; Fair, H; Fairhurst, S; Fan, X; Fang, Q; Farinon, S; Farr, B; Farr, W M; Favata, M; Fays, M; Fehrmann, H; Fejer, M M; Ferrante, I; Ferreira, E C; Ferrini, F; Fidecaro, F; Fiori, I; Fiorucci, D; Fisher, R P; Flaminio, R; Fletcher, M; Fournier, J-D; Franco, S; Frasca, S; Frasconi, F; Frei, Z; Freise, A; Frey, R; Frey, V; Fricke, T T; Fritschel, P; Frolov, V V; Fulda, P; Fyffe, M; Gabbard, H A G; Gair, J R; Gammaitoni, L; Gaonkar, S G; Garufi, F; Gatto, A; Gaur, G; Gehrels, N; Gemme, G; Gendre, B; Genin, E; Gennai, A; George, J; Gergely, L; Germain, V; Ghosh, Abhirup; Ghosh, Archisman; Ghosh, S; Giaime, J A; Giardina, K D; Giazotto, A; Gill, K; Glaefke, A; Goetz, E; Goetz, R; Gondan, L; González, G; Gonzalez Castro, J M; Gopakumar, A; Gordon, N A; Gorodetsky, M L; Gossan, S E; Gosselin, M; Gouaty, R; Graef, C; Graff, P B; Granata, M; Grant, A; Gras, S; Gray, C; Greco, G; Green, A C; Groot, P; Grote, H; Grunewald, S; Guidi, G M; Guo, X; Gupta, A; Gupta, M K; Gushwa, K E; Gustafson, E K; Gustafson, R; Hacker, J J; Hall, B R; Hall, E D; Hammond, G; Haney, M; Hanke, M M; Hanks, J; Hanna, C; Hannam, M D; Hanson, J; Hardwick, T; Harms, J; Harry, G M; Harry, I W; Hart, M J; Hartman, M T; Haster, C-J; Haughian, K; Healy, J; Heidmann, A; Heintze, M C; Heitmann, H; Hello, P; Hemming, G; Hendry, M; Heng, I S; Hennig, J; Heptonstall, A W; Heurs, M; Hild, S; Hoak, D; Hodge, K A; Hofman, D; Hollitt, S E; Holt, K; Holz, D E; Hopkins, P; Hosken, D J; Hough, J; Houston, E A; Howell, E J; Hu, Y M; Huang, S; Huerta, E A; Huet, D; Hughey, B; Husa, S; Huttner, S H; Huynh-Dinh, T; Idrisy, A; Indik, N; Ingram, D R; Inta, R; Isa, H N; Isac, J-M; Isi, M; Islas, G; Isogai, T; Iyer, B R; Izumi, K; Jacqmin, T; Jang, H; Jani, K; Jaranowski, P; Jawahar, S; Jiménez-Forteza, F; Johnson, W W; Johnson-McDaniel, N K; Jones, D I; Jones, R; Jonker, R J G; Ju, L; Haris, M K; Kalaghatgi, C V; Kalogera, V; Kandhasamy, S; Kang, G; Kanner, J B; Karki, S; Kasprzack, M; Katsavounidis, E; Katzman, W; Kaufer, S; Kaur, T; Kawabe, K; Kawazoe, F; Kéfélian, F; Kehl, M S; Keitel, D; Kelley, D B; Kells, W; Kennedy, R; Key, J S; Khalaidovski, A; Khalili, F Y; Khan, I; Khan, S; Khan, Z; Khazanov, E A; Kijbunchoo, N; Kim, C; Kim, J; Kim, K; Kim, Nam-Gyu; Kim, Namjun; Kim, Y-M; King, E J; King, P J; Kinzel, D L; Kissel, J S; Kleybolte, L; Klimenko, S; Koehlenbeck, S M; Kokeyama, K; Koley, S; Kondrashov, V; Kontos, A; Korobko, M; Korth, W Z; Kowalska, I; Kozak, D B; Kringel, V; Krishnan, B; Królak, A; Krueger, C; Kuehn, G; Kumar, P; Kuo, L; Kutynia, A; Lackey, B D; Landry, M; Lange, J; Lantz, B; Lasky, P D; Lazzarini, A; Lazzaro, C; Leaci, P; Leavey, S; Lebigot, E O; Lee, C H; Lee, H K; Lee, H M; Lee, K; Lenon, A; Leonardi, M; Leong, J R; Leroy, N; Letendre, N; Levin, Y; Levine, B M; Li, T G F; Libson, A; Littenberg, T B; Lockerbie, N A; Logue, J; Lombardi, A L; London, L T; Lord, J E; Lorenzini, M; Loriette, V; Lormand, M; Losurdo, G; Lough, J D; Lousto, C O; Lovelace, G; Lück, H; Lundgren, A P; Luo, J; Lynch, R; Ma, Y; MacDonald, T; Machenschalk, B; MacInnis, M; Macleod, D M; Magaña-Sandoval, F; Magee, R M; Mageswaran, M; Majorana, E; Maksimovic, I; Malvezzi, V; Man, N; Mandel, I; Mandic, V; Mangano, V; Mansell, G L; Manske, M; Mantovani, M; Marchesoni, F; Marion, F; Márka, S; Márka, Z; Markosyan, A S; Maros, E; Martelli, F; Martellini, L; Martin, I W; Martin, R M; Martynov, D V; Marx, J N; Mason, K; Masserot, A; Massinger, T J; Masso-Reid, M; Matichard, F; Matone, L; Mavalvala, N; Mazumder, N; Mazzolo, G; McCarthy, R; McClelland, D E; McCormick, S; McGuire, S C; McIntyre, G; McIver, J; McManus, D J; McWilliams, S T; Meacher, D; Meadors, G D; Meidam, J; Melatos, A; Mendell, G; Mendoza-Gandara, D; Mercer, R A; Merilh, E; Merzougui, M; Meshkov, S; Messenger, C; Messick, C; Meyers, P M; Mezzani, F; Miao, H; Michel, C; Middleton, H; Mikhailov, E E; Milano, L; Miller, J; Millhouse, M; Minenkov, Y; Ming, J; Mirshekari, S; Mishra, C; Mitra, S; Mitrofanov, V P; Mitselmakher, G; Mittleman, R; Moggi, A; Mohan, M; Mohapatra, S R P; Montani, M; Moore, B C; Moore, C J; Moraru, D; Moreno, G; Morriss, S R; Mossavi, K; Mours, B; Mow-Lowry, C M; Mueller, C L; Mueller, G; Muir, A W; Mukherjee, Arunava; Mukherjee, D; Mukherjee, S; Mukund, N; Mullavey, A; Munch, J; Murphy, D J; Murray, P G; Mytidis, A; Nardecchia, I; Naticchioni, L; Nayak, R K; Necula, V; Nedkova, K; Nelemans, G; Neri, M; Neunzert, A; Newton, G; Nguyen, T T; Nielsen, A B; Nissanke, S; Nitz, A; Nocera, F; Nolting, D; Normandin, M E; Nuttall, L K; Oberling, J; Ochsner, E; O'Dell, J; Oelker, E; Ogin, G H; Oh, J J; Oh, S H; Ohme, F; Oliver, M; Oppermann, P; Oram, Richard J; O'Reilly, B; O'Shaughnessy, R; Ottaway, D J; Ottens, R S; Overmier, H; Owen, B J; Pai, A; Pai, S A; Palamos, J R; Palashov, O; Palomba, C; Pal-Singh, A; Pan, H; Pan, Y; Pankow, C; Pannarale, F; Pant, B C; Paoletti, F; Paoli, A; Papa, M A; Paris, H R; Parker, W; Pascucci, D; Pasqualetti, A; Passaquieti, R; Passuello, D; Patricelli, B; Patrick, Z; Pearlstone, B L; Pedraza, M; Pedurand, R; Pekowsky, L; Pele, A; Penn, S; Perreca, A; Pfeiffer, H P; Phelps, M; Piccinni, O; Pichot, M; Piergiovanni, F; Pierro, V; Pillant, G; Pinard, L; Pinto, I M; Pitkin, M; Poggiani, R; Popolizio, P; Post, A; Powell, J; Prasad, J; Predoi, V; Premachandra, S S; Prestegard, T; Price, L R; Prijatelj, M; Principe, M; Privitera, S; Prix, R; Prodi, G A; Prokhorov, L; Puncken, O; Punturo, M; Puppo, P; Pürrer, M; Qi, H; Qin, J; Quetschke, V; Quintero, E A; Quitzow-James, R; Raab, F J; Rabeling, D S; Radkins, H; Raffai, P; Raja, S; Rakhmanov, M; Rapagnani, P; Raymond, V; Razzano, M; Re, V; Read, J; Reed, C M; Regimbau, T; Rei, L; Reid, S; Reitze, D H; Rew, H; Reyes, S D; Ricci, F; Riles, K; Robertson, N A; Robie, R; Robinet, F; Rocchi, A; Rolland, L; Rollins, J G; Roma, V J; Romano, R; Romanov, G; Romie, J H; Rosińska, D; Rowan, S; Rüdiger, A; Ruggi, P; Ryan, K; Sachdev, S; Sadecki, T; Sadeghian, L; Salconi, L; Saleem, M; Salemi, F; Samajdar, A; Sammut, L; Sanchez, E J; Sandberg, V; Sandeen, B; Sanders, J R; Sassolas, B; Sathyaprakash, B S; Saulson, P R; Sauter, O; Savage, R L; Sawadsky, A; Schale, P; Schilling, R; Schmidt, J; Schmidt, P; Schnabel, R; Schofield, R M S; Schönbeck, A; Schreiber, E; Schuette, D; Schutz, B F; Scott, J; Scott, S M; Sellers, D; Sengupta, A S; Sentenac, D; Sequino, V; Sergeev, A; Serna, G; Setyawati, Y; Sevigny, A; Shaddock, D A; Shah, S; Shahriar, M S; Shaltev, M; Shao, Z; Shapiro, B; Shawhan, P; Sheperd, A; Shoemaker, D H; Shoemaker, D M; Siellez, K; Siemens, X; Sigg, D; Silva, A D; Simakov, D; Singer, A; Singer, L P; Singh, A; Singh, R; Singhal, A; Sintes, A M; Slagmolen, B J J; Smith, J R; Smith, N D; Smith, R J E; Son, E J; Sorazu, B; Sorrentino, F; Souradeep, T; Srivastava, A K; Staley, A; Steinke, M; Steinlechner, J; Steinlechner, S; Steinmeyer, D; Stephens, B C; Stone, R; Strain, K A; Straniero, N; Stratta, G; Strauss, N A; Strigin, S; Sturani, R; Stuver, A L; Summerscales, T Z; Sun, L; Sutton, P J; Swinkels, B L; Szczepańczyk, M J; Tacca, M; Talukder, D; Tanner, D B; Tápai, M; Tarabrin, S P; Taracchini, A; Taylor, R; Theeg, T; Thirugnanasambandam, M P; Thomas, E G; Thomas, M; Thomas, P; Thorne, K A; Thorne, K S; Thrane, E; Tiwari, S; Tiwari, V; Tokmakov, K V; Tomlinson, C; Tonelli, M; Torres, C V; Torrie, C I; Töyrä, D; Travasso, F; Traylor, G; Trifirò, D; Tringali, M C; Trozzo, L; Tse, M; Turconi, M; Tuyenbayev, D; Ugolini, D; Unnikrishnan, C S; Urban, A L; Usman, S A; Vahlbruch, H; Vajente, G; Valdes, G; Vallisneri, M; van Bakel, N; van Beuzekom, M; van den Brand, J F J; Van Den Broeck, C; Vander-Hyde, D C; van der Schaaf, L; van Heijningen, J V; van Veggel, A A; Vardaro, M; Vass, S; Vasúth, M; Vaulin, R; Vecchio, A; Vedovato, G; Veitch, J; Veitch, P J; Venkateswara, K; Verkindt, D; Vetrano, F; Viceré, A; Vinciguerra, S; Vine, D J; Vinet, J-Y; Vitale, S; Vo, T; Vocca, H; Vorvick, C; Voss, D; Vousden, W D; Vyatchanin, S P; Wade, A R; Wade, L E; Wade, M; Walker, M; Wallace, L; Walsh, S; Wang, G; Wang, H; Wang, M; Wang, X; Wang, Y; Ward, R L; Warner, J; Was, M; Weaver, B; Wei, L-W; Weinert, M; Weinstein, A J; Weiss, R; Welborn, T; Wen, L; Weßels, P; Westphal, T; Wette, K; Whelan, J T; White, D J; Whiting, B F; Williams, D; Williams, R D; Williamson, A R; Willis, J L; Willke, B; Wimmer, M H; Winkler, W; Wipf, C C; Wittel, H; Woan, G; Worden, J; Wright, J L; Wu, G; Yablon, J; Yam, W; Yamamoto, H; Yancey, C C; Yap, M J; Yu, H; Yvert, M; Zadrożny, A; Zangrando, L; Zanolin, M; Zendri, J-P; Zevin, M; Zhang, F; Zhang, L; Zhang, M; Zhang, Y; Zhao, C; Zhou, M; Zhou, Z; Zhu, X J; Zucker, M E; Zuraw, S E; Zweizig, J; Boyle, M; Campanelli, M; Hemberger, D A; Kidder, L E; Ossokine, S; Scheel, M A; Szilagyi, B; Teukolsky, S; Zlochower, Y

    2016-06-01

    The LIGO detection of GW150914 provides an unprecedented opportunity to study the two-body motion of a compact-object binary in the large-velocity, highly nonlinear regime, and to witness the final merger of the binary and the excitation of uniquely relativistic modes of the gravitational field. We carry out several investigations to determine whether GW150914 is consistent with a binary black-hole merger in general relativity. We find that the final remnant's mass and spin, as determined from the low-frequency (inspiral) and high-frequency (postinspiral) phases of the signal, are mutually consistent with the binary black-hole solution in general relativity. Furthermore, the data following the peak of GW150914 are consistent with the least-damped quasinormal mode inferred from the mass and spin of the remnant black hole. By using waveform models that allow for parametrized general-relativity violations during the inspiral and merger phases, we perform quantitative tests on the gravitational-wave phase in the dynamical regime and we determine the first empirical bounds on several high-order post-Newtonian coefficients. We constrain the graviton Compton wavelength, assuming that gravitons are dispersed in vacuum in the same way as particles with mass, obtaining a 90%-confidence lower bound of 10^{13}  km. In conclusion, within our statistical uncertainties, we find no evidence for violations of general relativity in the genuinely strong-field regime of gravity. PMID:27314708

  10. General Relativity theory: tests through time

    NASA Astrophysics Data System (ADS)

    Yatskiv, Ya. S.; Alexandrov, A. N.; Vavilova, I. B.; Zhdanov, V. I.; Kudrya, Yu. N.; Parnovsky, S. L.; Fedorova, O. V.; Khmil, S. V.

    2005-09-01

    Theoretical basis of General relativity Theory, its experimental tests as well as GRT applications are briefly summarized taking into account the results of the last decade. The monograph addresses scientists, post-graduated students, and students specialized in the natural sciences as well as everyone who takes a great interest in GRT.

  11. Does Physics Need Special and General Relativity?

    NASA Astrophysics Data System (ADS)

    Dunning-Davies, Jeremy

    Here it is intended to reconsider briefly some of the objections which have arisen over the years to both the Special and General Theories of Relativity before raising the question of whether or not either of these two theories is actually required by modern physics.

  12. Tests of General Relativity with GW150914

    NASA Astrophysics Data System (ADS)

    Abbott, B. P.; Abbott, R.; Abbott, T. D.; Abernathy, M. R.; Acernese, F.; Ackley, K.; Adams, C.; Adams, T.; Addesso, P.; Adhikari, R. X.; Adya, V. B.; Affeldt, C.; Agathos, M.; Agatsuma, K.; Aggarwal, N.; Aguiar, O. D.; Aiello, L.; Ain, A.; Ajith, P.; Allen, B.; Allocca, A.; Altin, P. A.; Anderson, S. B.; Anderson, W. G.; Arai, K.; Araya, M. C.; Arceneaux, C. C.; Areeda, J. S.; Arnaud, N.; Arun, K. G.; Ascenzi, S.; Ashton, G.; Ast, M.; Aston, S. M.; Astone, P.; Aufmuth, P.; Aulbert, C.; Babak, S.; Bacon, P.; Bader, M. K. M.; Baker, P. T.; Baldaccini, F.; Ballardin, G.; Ballmer, S. W.; Barayoga, J. C.; Barclay, S. E.; Barish, B. C.; Barker, D.; Barone, F.; Barr, B.; Barsotti, L.; Barsuglia, M.; Barta, D.; Bartlett, J.; Bartos, I.; Bassiri, R.; Basti, A.; Batch, J. C.; Baune, C.; Bavigadda, V.; Bazzan, M.; Behnke, B.; Bejger, M.; Bell, A. S.; Bell, C. J.; Berger, B. K.; Bergman, J.; Bergmann, G.; Berry, C. P. L.; Bersanetti, D.; Bertolini, A.; Betzwieser, J.; Bhagwat, S.; Bhandare, R.; Bilenko, I. A.; Billingsley, G.; Birch, J.; Birney, R.; Birnholtz, O.; Biscans, S.; Bisht, A.; Bitossi, M.; Biwer, C.; Bizouard, M. A.; Blackburn, J. K.; Blair, C. D.; Blair, D. G.; Blair, R. M.; Bloemen, S.; Bock, O.; Bodiya, T. P.; Boer, M.; Bogaert, G.; Bogan, C.; Bohe, A.; Bojtos, P.; Bond, C.; Bondu, F.; Bonnand, R.; Boom, B. A.; Bork, R.; Boschi, V.; Bose, S.; Bouffanais, Y.; Bozzi, A.; Bradaschia, C.; Brady, P. R.; Braginsky, V. B.; Branchesi, M.; Brau, J. E.; Briant, T.; Brillet, A.; Brinkmann, M.; Brisson, V.; Brockill, P.; Brooks, A. F.; Brown, D. A.; Brown, D. D.; Brown, N. M.; Buchanan, C. C.; Buikema, A.; Bulik, T.; Bulten, H. J.; Buonanno, A.; Buskulic, D.; Buy, C.; Byer, R. L.; Cadonati, L.; Cagnoli, G.; Cahillane, C.; Calderón Bustillo, J.; Callister, T.; Calloni, E.; Camp, J. B.; Cannon, K. C.; Cao, J.; Capano, C. D.; Capocasa, E.; Carbognani, F.; Caride, S.; Casanueva Diaz, J.; Casentini, C.; Caudill, S.; Cavaglià, M.; Cavalier, F.; Cavalieri, R.; Cella, G.; Cepeda, C. B.; Cerboni Baiardi, L.; Cerretani, G.; Cesarini, E.; Chakraborty, R.; Chalermsongsak, T.; Chamberlin, S. J.; Chan, M.; Chao, S.; Charlton, P.; Chassande-Mottin, E.; Chen, H. Y.; Chen, Y.; Cheng, C.; Chincarini, A.; Chiummo, A.; Cho, H. S.; Cho, M.; Chow, J. H.; Christensen, N.; Chu, Q.; Chua, S.; Chung, S.; Ciani, G.; Clara, F.; Clark, J. A.; Cleva, F.; Coccia, E.; Cohadon, P.-F.; Colla, A.; Collette, C. G.; Cominsky, L.; Constancio, M.; Conte, A.; Conti, L.; Cook, D.; Corbitt, T. R.; Cornish, N.; Corsi, A.; Cortese, S.; Costa, C. A.; Coughlin, M. W.; Coughlin, S. B.; Coulon, J.-P.; Countryman, S. T.; Couvares, P.; Cowan, E. E.; Coward, D. M.; Cowart, M. J.; Coyne, D. C.; Coyne, R.; Craig, K.; Creighton, J. D. E.; Cripe, J.; Crowder, S. G.; Cumming, A.; Cunningham, L.; Cuoco, E.; Dal Canton, T.; Danilishin, S. L.; D'Antonio, S.; Danzmann, K.; Darman, N. S.; Dattilo, V.; Dave, I.; Daveloza, H. P.; Davier, M.; Davies, G. S.; Daw, E. J.; Day, R.; DeBra, D.; Debreczeni, G.; Degallaix, J.; De Laurentis, M.; Deléglise, S.; Del Pozzo, W.; Denker, T.; Dent, T.; Dereli, H.; Dergachev, V.; De Rosa, R.; DeRosa, R. T.; DeSalvo, R.; Dhurandhar, S.; Díaz, M. C.; Di Fiore, L.; Di Giovanni, M.; Di Lieto, A.; Di Pace, S.; Di Palma, I.; Di Virgilio, A.; Dojcinoski, G.; Dolique, V.; Donovan, F.; Dooley, K. L.; Doravari, S.; Douglas, R.; Downes, T. P.; Drago, M.; Drever, R. W. P.; Driggers, J. C.; Du, Z.; Ducrot, M.; Dwyer, S. E.; Edo, T. B.; Edwards, M. C.; Effler, A.; Eggenstein, H.-B.; Ehrens, P.; Eichholz, J.; Eikenberry, S. S.; Engels, W.; Essick, R. C.; Etzel, T.; Evans, M.; Evans, T. M.; Everett, R.; Factourovich, M.; Fafone, V.; Fair, H.; Fairhurst, S.; Fan, X.; Fang, Q.; Farinon, S.; Farr, B.; Farr, W. M.; Favata, M.; Fays, M.; Fehrmann, H.; Fejer, M. M.; Ferrante, I.; Ferreira, E. C.; Ferrini, F.; Fidecaro, F.; Fiori, I.; Fiorucci, D.; Fisher, R. P.; Flaminio, R.; Fletcher, M.; Fournier, J.-D.; Franco, S.; Frasca, S.; Frasconi, F.; Frei, Z.; Freise, A.; Frey, R.; Frey, V.; Fricke, T. T.; Fritschel, P.; Frolov, V. V.; Fulda, P.; Fyffe, M.; Gabbard, H. A. G.; Gair, J. R.; Gammaitoni, L.; Gaonkar, S. G.; Garufi, F.; Gatto, A.; Gaur, G.; Gehrels, N.; Gemme, G.; Gendre, B.; Genin, E.; Gennai, A.; George, J.; Gergely, L.; Germain, V.; Ghosh, Abhirup; Ghosh, Archisman; Ghosh, S.; Giaime, J. A.; Giardina, K. D.; Giazotto, A.; Gill, K.; Glaefke, A.; Goetz, E.; Goetz, R.; Gondan, L.; González, G.; Gonzalez Castro, J. M.; Gopakumar, A.; Gordon, N. A.; Gorodetsky, M. L.; Gossan, S. E.; Gosselin, M.; Gouaty, R.; Graef, C.; Graff, P. B.; Granata, M.; Grant, A.; Gras, S.; Gray, C.; Greco, G.; Green, A. C.; Groot, P.; Grote, H.; Grunewald, S.; Guidi, G. M.; Guo, X.; Gupta, A.; Gupta, M. K.; Gushwa, K. E.; Gustafson, E. K.; Gustafson, R.; Hacker, J. J.; Hall, B. R.; Hall, E. D.; Hammond, G.; Haney, M.; Hanke, M. M.; Hanks, J.; Hanna, C.; Hannam, M. D.; Hanson, J.; Hardwick, T.; Harms, J.; Harry, G. M.; Harry, I. W.; Hart, M. J.; Hartman, M. T.; Haster, C.-J.; Haughian, K.; Healy, J.; Heidmann, A.; Heintze, M. C.; Heitmann, H.; Hello, P.; Hemming, G.; Hendry, M.; Heng, I. S.; Hennig, J.; Heptonstall, A. W.; Heurs, M.; Hild, S.; Hoak, D.; Hodge, K. A.; Hofman, D.; Hollitt, S. E.; Holt, K.; Holz, D. E.; Hopkins, P.; Hosken, D. J.; Hough, J.; Houston, E. A.; Howell, E. J.; Hu, Y. M.; Huang, S.; Huerta, E. A.; Huet, D.; Hughey, B.; Husa, S.; Huttner, S. H.; Huynh-Dinh, T.; Idrisy, A.; Indik, N.; Ingram, D. R.; Inta, R.; Isa, H. N.; Isac, J.-M.; Isi, M.; Islas, G.; Isogai, T.; Iyer, B. R.; Izumi, K.; Jacqmin, T.; Jang, H.; Jani, K.; Jaranowski, P.; Jawahar, S.; Jiménez-Forteza, F.; Johnson, W. W.; Johnson-McDaniel, N. K.; Jones, D. I.; Jones, R.; Jonker, R. J. G.; Ju, L.; Haris, M. K.; Kalaghatgi, C. V.; Kalogera, V.; Kandhasamy, S.; Kang, G.; Kanner, J. B.; Karki, S.; Kasprzack, M.; Katsavounidis, E.; Katzman, W.; Kaufer, S.; Kaur, T.; Kawabe, K.; Kawazoe, F.; Kéfélian, F.; Kehl, M. S.; Keitel, D.; Kelley, D. B.; Kells, W.; Kennedy, R.; Key, J. S.; Khalaidovski, A.; Khalili, F. Y.; Khan, I.; Khan, S.; Khan, Z.; Khazanov, E. A.; Kijbunchoo, N.; Kim, C.; Kim, J.; Kim, K.; Kim, Nam-Gyu; Kim, Namjun; Kim, Y.-M.; King, E. J.; King, P. J.; Kinzel, D. L.; Kissel, J. S.; Kleybolte, L.; Klimenko, S.; Koehlenbeck, S. M.; Kokeyama, K.; Koley, S.; Kondrashov, V.; Kontos, A.; Korobko, M.; Korth, W. Z.; Kowalska, I.; Kozak, D. B.; Kringel, V.; Krishnan, B.; Królak, A.; Krueger, C.; Kuehn, G.; Kumar, P.; Kuo, L.; Kutynia, A.; Lackey, B. D.; Landry, M.; Lange, J.; Lantz, B.; Lasky, P. D.; Lazzarini, A.; Lazzaro, C.; Leaci, P.; Leavey, S.; Lebigot, E. O.; Lee, C. H.; Lee, H. K.; Lee, H. M.; Lee, K.; Lenon, A.; Leonardi, M.; Leong, J. R.; Leroy, N.; Letendre, N.; Levin, Y.; Levine, B. M.; Li, T. G. F.; Libson, A.; Littenberg, T. B.; Lockerbie, N. A.; Logue, J.; Lombardi, A. L.; London, L. T.; Lord, J. E.; Lorenzini, M.; Loriette, V.; Lormand, M.; Losurdo, G.; Lough, J. D.; Lousto, C. O.; Lovelace, G.; Lück, H.; Lundgren, A. P.; Luo, J.; Lynch, R.; Ma, Y.; MacDonald, T.; Machenschalk, B.; MacInnis, M.; Macleod, D. M.; Magaña-Sandoval, F.; Magee, R. M.; Mageswaran, M.; Majorana, E.; Maksimovic, I.; Malvezzi, V.; Man, N.; Mandel, I.; Mandic, V.; Mangano, V.; Mansell, G. L.; Manske, M.; Mantovani, M.; Marchesoni, F.; Marion, F.; Márka, S.; Márka, Z.; Markosyan, A. S.; Maros, E.; Martelli, F.; Martellini, L.; Martin, I. W.; Martin, R. M.; Martynov, D. V.; Marx, J. N.; Mason, K.; Masserot, A.; Massinger, T. J.; Masso-Reid, M.; Matichard, F.; Matone, L.; Mavalvala, N.; Mazumder, N.; Mazzolo, G.; McCarthy, R.; McClelland, D. E.; McCormick, S.; McGuire, S. C.; McIntyre, G.; McIver, J.; McManus, D. J.; McWilliams, S. T.; Meacher, D.; Meadors, G. D.; Meidam, J.; Melatos, A.; Mendell, G.; Mendoza-Gandara, D.; Mercer, R. A.; Merilh, E.; Merzougui, M.; Meshkov, S.; Messenger, C.; Messick, C.; Meyers, P. M.; Mezzani, F.; Miao, H.; Michel, C.; Middleton, H.; Mikhailov, E. E.; Milano, L.; Miller, J.; Millhouse, M.; Minenkov, Y.; Ming, J.; Mirshekari, S.; Mishra, C.; Mitra, S.; Mitrofanov, V. P.; Mitselmakher, G.; Mittleman, R.; Moggi, A.; Mohan, M.; Mohapatra, S. R. P.; Montani, M.; Moore, B. C.; Moore, C. J.; Moraru, D.; Moreno, G.; Morriss, S. R.; Mossavi, K.; Mours, B.; Mow-Lowry, C. M.; Mueller, C. L.; Mueller, G.; Muir, A. W.; Mukherjee, Arunava; Mukherjee, D.; Mukherjee, S.; Mukund, N.; Mullavey, A.; Munch, J.; Murphy, D. J.; Murray, P. G.; Mytidis, A.; Nardecchia, I.; Naticchioni, L.; Nayak, R. K.; Necula, V.; Nedkova, K.; Nelemans, G.; Neri, M.; Neunzert, A.; Newton, G.; Nguyen, T. T.; Nielsen, A. B.; Nissanke, S.; Nitz, A.; Nocera, F.; Nolting, D.; Normandin, M. E.; Nuttall, L. K.; Oberling, J.; Ochsner, E.; O'Dell, J.; Oelker, E.; Ogin, G. H.; Oh, J. J.; Oh, S. H.; Ohme, F.; Oliver, M.; Oppermann, P.; Oram, Richard J.; O'Reilly, B.; O'Shaughnessy, R.; Ottaway, D. J.; Ottens, R. S.; Overmier, H.; Owen, B. J.; Pai, A.; Pai, S. A.; Palamos, J. R.; Palashov, O.; Palomba, C.; Pal-Singh, A.; Pan, H.; Pan, Y.; Pankow, C.; Pannarale, F.; Pant, B. C.; Paoletti, F.; Paoli, A.; Papa, M. A.; Paris, H. R.; Parker, W.; Pascucci, D.; Pasqualetti, A.; Passaquieti, R.; Passuello, D.; Patricelli, B.; Patrick, Z.; Pearlstone, B. L.; Pedraza, M.; Pedurand, R.; Pekowsky, L.; Pele, A.; Penn, S.; Perreca, A.; Pfeiffer, H. P.; Phelps, M.; Piccinni, O.; Pichot, M.; Piergiovanni, F.; Pierro, V.; Pillant, G.; Pinard, L.; Pinto, I. M.; Pitkin, M.; Poggiani, R.; Popolizio, P.; Post, A.; Powell, J.; Prasad, J.; Predoi, V.; Premachandra, S. S.; Prestegard, T.; Price, L. R.; Prijatelj, M.; Principe, M.; Privitera, S.; Prix, R.; Prodi, G. A.; Prokhorov, L.; Puncken, O.; Punturo, M.; Puppo, P.; Pürrer, M.; Qi, H.; Qin, J.; Quetschke, V.; Quintero, E. A.; Quitzow-James, R.; Raab, F. J.; Rabeling, D. S.; Radkins, H.; Raffai, P.; Raja, S.; Rakhmanov, M.; Rapagnani, P.; Raymond, V.; Razzano, M.; Re, V.; Read, J.; Reed, C. M.; Regimbau, T.; Rei, L.; Reid, S.; Reitze, D. H.; Rew, H.; Reyes, S. D.; Ricci, F.; Riles, K.; Robertson, N. A.; Robie, R.; Robinet, F.; Rocchi, A.; Rolland, L.; Rollins, J. G.; Roma, V. J.; Romano, R.; Romanov, G.; Romie, J. H.; Rosińska, D.; Rowan, S.; Rüdiger, A.; Ruggi, P.; Ryan, K.; Sachdev, S.; Sadecki, T.; Sadeghian, L.; Salconi, L.; Saleem, M.; Salemi, F.; Samajdar, A.; Sammut, L.; Sanchez, E. J.; Sandberg, V.; Sandeen, B.; Sanders, J. R.; Sassolas, B.; Sathyaprakash, B. S.; Saulson, P. R.; Sauter, O.; Savage, R. L.; Sawadsky, A.; Schale, P.; Schilling, R.; Schmidt, J.; Schmidt, P.; Schnabel, R.; Schofield, R. M. S.; Schönbeck, A.; Schreiber, E.; Schuette, D.; Schutz, B. F.; Scott, J.; Scott, S. M.; Sellers, D.; Sengupta, A. S.; Sentenac, D.; Sequino, V.; Sergeev, A.; Serna, G.; Setyawati, Y.; Sevigny, A.; Shaddock, D. A.; Shah, S.; Shahriar, M. S.; Shaltev, M.; Shao, Z.; Shapiro, B.; Shawhan, P.; Sheperd, A.; Shoemaker, D. H.; Shoemaker, D. M.; Siellez, K.; Siemens, X.; Sigg, D.; Silva, A. D.; Simakov, D.; Singer, A.; Singer, L. P.; Singh, A.; Singh, R.; Singhal, A.; Sintes, A. M.; Slagmolen, B. J. J.; Smith, J. R.; Smith, N. D.; Smith, R. J. E.; Son, E. J.; Sorazu, B.; Sorrentino, F.; Souradeep, T.; Srivastava, A. K.; Staley, A.; Steinke, M.; Steinlechner, J.; Steinlechner, S.; Steinmeyer, D.; Stephens, B. C.; Stone, R.; Strain, K. A.; Straniero, N.; Stratta, G.; Strauss, N. A.; Strigin, S.; Sturani, R.; Stuver, A. L.; Summerscales, T. Z.; Sun, L.; Sutton, P. J.; Swinkels, B. L.; Szczepańczyk, M. J.; Tacca, M.; Talukder, D.; Tanner, D. B.; Tápai, M.; Tarabrin, S. P.; Taracchini, A.; Taylor, R.; Theeg, T.; Thirugnanasambandam, M. P.; Thomas, E. G.; Thomas, M.; Thomas, P.; Thorne, K. A.; Thorne, K. S.; Thrane, E.; Tiwari, S.; Tiwari, V.; Tokmakov, K. V.; Tomlinson, C.; Tonelli, M.; Torres, C. V.; Torrie, C. I.; Töyrä, D.; Travasso, F.; Traylor, G.; Trifirò, D.; Tringali, M. C.; Trozzo, L.; Tse, M.; Turconi, M.; Tuyenbayev, D.; Ugolini, D.; Unnikrishnan, C. S.; Urban, A. L.; Usman, S. A.; Vahlbruch, H.; Vajente, G.; Valdes, G.; Vallisneri, M.; van Bakel, N.; van Beuzekom, M.; van den Brand, J. F. J.; Van Den Broeck, C.; Vander-Hyde, D. C.; van der Schaaf, L.; van Heijningen, J. V.; van Veggel, A. A.; Vardaro, M.; Vass, S.; Vasúth, M.; Vaulin, R.; Vecchio, A.; Vedovato, G.; Veitch, J.; Veitch, P. J.; Venkateswara, K.; Verkindt, D.; Vetrano, F.; Viceré, A.; Vinciguerra, S.; Vine, D. J.; Vinet, J.-Y.; Vitale, S.; Vo, T.; Vocca, H.; Vorvick, C.; Voss, D.; Vousden, W. D.; Vyatchanin, S. P.; Wade, A. R.; Wade, L. E.; Wade, M.; Walker, M.; Wallace, L.; Walsh, S.; Wang, G.; Wang, H.; Wang, M.; Wang, X.; Wang, Y.; Ward, R. L.; Warner, J.; Was, M.; Weaver, B.; Wei, L.-W.; Weinert, M.; Weinstein, A. J.; Weiss, R.; Welborn, T.; Wen, L.; Weßels, P.; Westphal, T.; Wette, K.; Whelan, J. T.; White, D. J.; Whiting, B. F.; Williams, D.; Williams, R. D.; Williamson, A. R.; Willis, J. L.; Willke, B.; Wimmer, M. H.; Winkler, W.; Wipf, C. C.; Wittel, H.; Woan, G.; Worden, J.; Wright, J. L.; Wu, G.; Yablon, J.; Yam, W.; Yamamoto, H.; Yancey, C. C.; Yap, M. J.; Yu, H.; Yvert, M.; ZadroŻny, A.; Zangrando, L.; Zanolin, M.; Zendri, J.-P.; Zevin, M.; Zhang, F.; Zhang, L.; Zhang, M.; Zhang, Y.; Zhao, C.; Zhou, M.; Zhou, Z.; Zhu, X. J.; Zucker, M. E.; Zuraw, S. E.; Zweizig, J.; Boyle, M.; Campanelli, M.; Hemberger, D. A.; Kidder, L. E.; Ossokine, S.; Scheel, M. A.; Szilagyi, B.; Teukolsky, S.; Zlochower, Y.; LIGO Scientific; Virgo Collaborations

    2016-06-01

    The LIGO detection of GW150914 provides an unprecedented opportunity to study the two-body motion of a compact-object binary in the large-velocity, highly nonlinear regime, and to witness the final merger of the binary and the excitation of uniquely relativistic modes of the gravitational field. We carry out several investigations to determine whether GW150914 is consistent with a binary black-hole merger in general relativity. We find that the final remnant's mass and spin, as determined from the low-frequency (inspiral) and high-frequency (postinspiral) phases of the signal, are mutually consistent with the binary black-hole solution in general relativity. Furthermore, the data following the peak of GW150914 are consistent with the least-damped quasinormal mode inferred from the mass and spin of the remnant black hole. By using waveform models that allow for parametrized general-relativity violations during the inspiral and merger phases, we perform quantitative tests on the gravitational-wave phase in the dynamical regime and we determine the first empirical bounds on several high-order post-Newtonian coefficients. We constrain the graviton Compton wavelength, assuming that gravitons are dispersed in vacuum in the same way as particles with mass, obtaining a 90%-confidence lower bound of 1013 km . In conclusion, within our statistical uncertainties, we find no evidence for violations of general relativity in the genuinely strong-field regime of gravity.

  13. Incidence of facial pain in the general population.

    PubMed

    Koopman, Joseph S H A; Dieleman, Jeanne P; Huygen, Frank J; de Mos, Marissa; Martin, Carola G M; Sturkenboom, Miriam C J M

    2009-12-15

    Facial pain has a considerable impact on quality of life. Accurate incidence estimates in the general population are scant. The aim was therefore to estimate the incidence rate (IR) of trigeminal neuralgia (TGN), postherpetic neuralgia (PHN), cluster headache (CH), occipital neuralgia (ON), local neuralgia (LoN), atypical facial pain (AFP), glossopharyngeal neuralgia (GPN) and paroxysmal hemicrania (PH) in the Netherlands. In the population-based Integrated Primary Care Information (IPCI) medical record database potential facial pain cases were identified from codes and narratives. Two medical doctors reviewed medical records, questionnaires from general practitioners and specialist letters using criteria of the International Association for the Study of Pain. A pain specialist arbitrated if necessary and a random sample of all cases was evaluated by a neurologist. The date of onset was defined as date of first specific symptoms. The IR was calculated per 100,000PY. Three hundred and sixty-two incident cases were ascertained. The overall IR [95% confidence interval] was 38.7 [34.9-42.9]. It was more common among women compared to men. Trigeminal neuralgia and cluster headache were the most common forms among the studied diseases. Paroxysmal hemicrania and glossopharyngeal neuralgia were among the rarer syndromes. The IR increased with age for all diseases except CH and ON, peaking in the 4th and 7th decade, respectively. Postherpetic neuralgia, CH and LoN were more common in men than women. From this we can conclude that facial pain is relatively rare, although more common than estimated previously based on hospital data. PMID:19783099

  14. General Relativity in the Undergraduate Physics Curriculum

    NASA Astrophysics Data System (ADS)

    Hartle, James

    2005-04-01

    Einstein's theory of gravitation --- general relativity--- will shortly be a century old. At is core is one of the most beautiful and revolutionary conceptions of modern science --- the idea that gravity is the geometry of four-dimensional curved spacetime. Together with quantum theory, general relativity is one of the two most profound developments of twentieth century physics. General relativity underlies our understanding of the universe on the largest distance scales, and is central to the the explanation of such frontier astrophysical phenomena gravitational collapse,black holes, X-ray sources, neutron stars, active galactic nuclei, gravitational waves, and the big bang. General relativity is the intellectual origin of many ideas in contemporary elementary particle physics such as string theory. This talk will make the case that an introduction to general relativity is naturally a part education of every undergraduate physics major, and describe a `physics first' approach to teaching at that level. The simplest physically relevant solutions of the Einstein equation, such as those representing black holes, simple cosmologies, and gravitational waves, are presented first without derivation. Their observational consequences are explored by the study of the motion of test particles and light rays in them.This brings the student to the physical phenomena as quickly aspossible. It is the part of the subject most directly connectedto classical mechanics, and requires the minimum of new mathematical ideas. The Einstein equation is introduced later to show where these geometries originate. A course for junior or senior level physics students based on theseprinciples has been part of the undergraduate curriculum at the University of California, Santa Barbara for several decades. It works.

  15. Modeling the brain morphology distribution in the general aging population

    NASA Astrophysics Data System (ADS)

    Huizinga, W.; Poot, D. H. J.; Roshchupkin, G.; Bron, E. E.; Ikram, M. A.; Vernooij, M. W.; Rueckert, D.; Niessen, W. J.; Klein, S.

    2016-03-01

    Both normal aging and neurodegenerative diseases such as Alzheimer's disease cause morphological changes of the brain. To better distinguish between normal and abnormal cases, it is necessary to model changes in brain morphology owing to normal aging. To this end, we developed a method for analyzing and visualizing these changes for the entire brain morphology distribution in the general aging population. The method is applied to 1000 subjects from a large population imaging study in the elderly, from which 900 were used to train the model and 100 were used for testing. The results of the 100 test subjects show that the model generalizes to subjects outside the model population. Smooth percentile curves showing the brain morphology changes as a function of age and spatiotemporal atlases derived from the model population are publicly available via an interactive web application at agingbrain.bigr.nl.

  16. Generalized population models and the nature of genetic drift.

    PubMed

    Der, Ricky; Epstein, Charles L; Plotkin, Joshua B

    2011-09-01

    The Wright-Fisher model of allele dynamics forms the basis for most theoretical and applied research in population genetics. Our understanding of genetic drift, and its role in suppressing the deterministic forces of Darwinian selection has relied on the specific form of sampling inherent to the Wright-Fisher model and its diffusion limit. Here we introduce and analyze a broad class of forward-time population models that share the same mean and variance as the Wright-Fisher model, but may otherwise differ. The proposed class unifies and further generalizes a number of population-genetic processes of recent interest, including the Λ and Cannings processes. Even though these models all have the same variance effective population size, they encode a rich diversity of alternative forms of genetic drift, with significant consequences for allele dynamics. We characterize in detail the behavior of standard population-genetic quantities across this family of generalized models. Some quantities, such as heterozygosity, remain unchanged; but others, such as neutral absorption times and fixation probabilities under selection, deviate by orders of magnitude from the Wright-Fisher model. We show that generalized population models can produce startling phenomena that differ qualitatively from classical behavior - such as assured fixation of a new mutant despite the presence of genetic drift. We derive the forward-time continuum limits of the generalized processes, analogous to Kimura's diffusion limit of the Wright-Fisher process, and we discuss their relationships to the Kingman and non-Kingman coalescents. Finally, we demonstrate that some non-diffusive, generalized models are more likely, in certain respects, than the Wright-Fisher model itself, given empirical data from Drosophila populations. PMID:21718713

  17. A general method for modeling population dynamics and its applications.

    PubMed

    Shestopaloff, Yuri K

    2013-12-01

    Studying populations, be it a microbe colony or mankind, is important for understanding how complex systems evolve and exist. Such knowledge also often provides insights into evolution, history and different aspects of human life. By and large, populations' prosperity and decline is about transformation of certain resources into quantity and other characteristics of populations through growth, replication, expansion and acquisition of resources. We introduce a general model of population change, applicable to different types of populations, which interconnects numerous factors influencing population dynamics, such as nutrient influx and nutrient consumption, reproduction period, reproduction rate, etc. It is also possible to take into account specific growth features of individual organisms. We considered two recently discovered distinct growth scenarios: first, when organisms do not change their grown mass regardless of nutrients availability, and the second when organisms can reduce their grown mass by several times in a nutritionally poor environment. We found that nutrient supply and reproduction period are two major factors influencing the shape of population growth curves. There is also a difference in population dynamics between these two groups. Organisms belonging to the second group are significantly more adaptive to reduction of nutrients and far more resistant to extinction. Also, such organisms have substantially more frequent and lesser in amplitude fluctuations of population quantity for the same periodic nutrient supply (compared to the first group). Proposed model allows adequately describing virtually any possible growth scenario, including complex ones with periodic and irregular nutrient supply and other changing parameters, which present approaches cannot do. PMID:24057917

  18. Evolutionary dynamics of general group interactions in structured populations.

    PubMed

    Li, Aming; Broom, Mark; Du, Jinming; Wang, Long

    2016-02-01

    The evolution of populations is influenced by many factors, and the simple classical models have been developed in a number of important ways. Both population structure and multiplayer interactions have been shown to significantly affect the evolution of important properties, such as the level of cooperation or of aggressive behavior. Here we combine these two key factors and develop the evolutionary dynamics of general group interactions in structured populations represented by regular graphs. The traditional linear and threshold public goods games are adopted as models to address the dynamics. We show that for linear group interactions, population structure can favor the evolution of cooperation compared to the well-mixed case, and we see that the more neighbors there are, the harder it is for cooperators to persist in structured populations. We further show that threshold group interactions could lead to the emergence of cooperation even in well-mixed populations. Here population structure sometimes inhibits cooperation for the threshold public goods game, where depending on the benefit to cost ratio, the outcomes are bistability or a monomorphic population of defectors or cooperators. Our results suggest, counterintuitively, that structured populations are not always beneficial for the evolution of cooperation for nonlinear group interactions. PMID:26986362

  19. Evolutionary dynamics of general group interactions in structured populations

    NASA Astrophysics Data System (ADS)

    Li, Aming; Broom, Mark; Du, Jinming; Wang, Long

    2016-02-01

    The evolution of populations is influenced by many factors, and the simple classical models have been developed in a number of important ways. Both population structure and multiplayer interactions have been shown to significantly affect the evolution of important properties, such as the level of cooperation or of aggressive behavior. Here we combine these two key factors and develop the evolutionary dynamics of general group interactions in structured populations represented by regular graphs. The traditional linear and threshold public goods games are adopted as models to address the dynamics. We show that for linear group interactions, population structure can favor the evolution of cooperation compared to the well-mixed case, and we see that the more neighbors there are, the harder it is for cooperators to persist in structured populations. We further show that threshold group interactions could lead to the emergence of cooperation even in well-mixed populations. Here population structure sometimes inhibits cooperation for the threshold public goods game, where depending on the benefit to cost ratio, the outcomes are bistability or a monomorphic population of defectors or cooperators. Our results suggest, counterintuitively, that structured populations are not always beneficial for the evolution of cooperation for nonlinear group interactions.

  20. Geoids in general relativity: geoid quasilocal frames

    NASA Astrophysics Data System (ADS)

    Oltean, Marius; Epp, Richard J.; McGrath, Paul L.; Mann, Robert B.

    2016-05-01

    We develop, in the context of general relativity, the notion of a geoid—a surface of constant ‘gravitational potential’. In particular, we show how this idea naturally emerges as a specific choice of a previously proposed, more general and operationally useful construction called a quasilocal frame—that is, a choice of a two-parameter family of timelike worldlines comprising the worldtube boundary of the history of a finite spatial volume. We study the geometric properties of these geoid quasilocal frames, and construct solutions for them in some simple spacetimes. We then compare these results—focusing on the computationally tractable scenario of a non-rotating body with a quadrupole perturbation—against their counterparts in Newtonian gravity (the setting for current applications of the geoid), and we compute general-relativistic corrections to some measurable geometric quantities.

  1. Confronting general relativity with further cosmological data

    SciTech Connect

    Daniel, Scott F.; Linder, Eric V.

    2010-11-15

    Deviations from general relativity in order to explain cosmic acceleration generically have both time and scale-dependent signatures in cosmological data. We extend our previous work by investigating model-independent gravitational deviations in bins of redshift and length scale, by incorporating further cosmological probes such as temperature-galaxy and galaxy-galaxy cross-correlations, and by examining correlations between deviations. Markov Chain Monte Carlo likelihood analysis of the model-independent parameters fitting current data indicates that at low redshift general relativity deviates from the best fit at the 99% confidence level. We trace this to two different properties of the CFHTLS weak lensing data set and demonstrate that COSMOS weak lensing data does not show such deviation. Upcoming galaxy survey data will greatly improve the ability to test time and scale-dependent extensions to gravity and we calculate the constraints that the BigBOSS galaxy redshift survey could enable.

  2. Probing the Higgs vacuum with general relativity

    NASA Technical Reports Server (NTRS)

    Mannheim, Philip D.; Kazanas, Demosthenes

    1991-01-01

    It is shown that the structure of the Higgs vacuum can be revealed in gravitational experiments which probe the Schwarzschild geometry to only one order in MG/r beyond that needed for the classical tests of general relativity. The possibility that deviations from the conventional geometry are at least theoretically conceivable is explored. The deviations obtained provide a diagnostic test for searching for the existence of macroscopic scalar fields and open up the possiblity for further exploring the Higgs mechanism.

  3. Teaching General Relativity to the Layperson

    NASA Astrophysics Data System (ADS)

    Egdall, Mark

    2009-11-01

    This paper describes a lay course on general relativity (GR) given at the Osher Lifelong Learning Institute at Florida International University. It is presented in six hour-and-a-half weekly sessions. Other courses offered by the author include special relativity (which precedes the course described here), quantum theory, and cosmology. Students are people 50 and older, mostly retired or semi-retired like me. They come from all walks of life, including medical doctors, ballet directors, educators, cruise line executives, and poets. Most are college educated, but with little or no formal physics education. A few have technical backgrounds, e.g., chemistry or physics.

  4. Tests of General Theory of Relativity

    NASA Astrophysics Data System (ADS)

    Brynjolfsson, Ari

    2002-04-01

    Einstein’s theory of general relativity and experiments proving it are all in the domain of classical physics. These include experiments by Pound, Rebka, and Snider of the gravitational redshift of 14.4 keV photons; the rocket experiments by Vessot et al.; the Galileo redshift experiments by Krisher et al.; the gravitational deflection of light experiments by Riveros and Vucetich; and delay of echoes of radar signals passing close to Sun as observed by Shapiro et al. Bohr’s correspondence principle assures that the quantum mechanical theory of general relativity agrees with Einstein’s classical theory when frequency and gravitational field gradient approach zero, or when photons cannot interact with the gravitational field. Quantum theory invalidates some of the assumption made by Einstein. His argument that equally many crests of waves must arrive on Earth as leave Sun is correct in classical physics, but impermissible in quantum mechanics. We will show that solar redshift experiments contradict the classical theory and support a quantum mechanically modified theory of general relativity. This changes drastically the entire theory, including the equivalence principle.

  5. Impact of obesity-related genes in Spanish population

    PubMed Central

    2013-01-01

    Background The objective was to investigate the association between BMI and single nucleotide polymorphisms previously identified of obesity-related genes in two Spanish populations. Forty SNPs in 23 obesity-related genes were evaluated in a rural population characterized by a high prevalence of obesity (869 subjects, mean age 46 yr, 62% women, 36% obese) and in an urban population (1425 subjects, mean age 54 yr, 50% women, 19% obese). Genotyping was assessed by using SNPlex and PLINK for the association analysis. Results Polymorphisms of the FTO were significantly associated with BMI, in the rural population (beta 0.87, p-value <0.001). None of the other SNPs showed significant association after Bonferroni correction in the two populations or in the pooled analysis. A weighted genetic risk score (wGRS) was constructed using the risk alleles of the Tag-SNPs with a positive Beta parameter in both populations. From the first to the fifth quintile of the score, the BMI increased 0.45 kg/m2 in Hortega and 2.0 kg/m2 in Pizarra. Overall, the obesity predictive value was low (less than 1%). Conclusion The risk associated with polymorphisms is low and the overall effect on BMI or obesity prediction is minimal. A weighted genetic risk score based on genes mainly acting through central nervous system mechanisms was associated with BMI but it yields minimal clinical prediction for the obesity risk in the general population. PMID:24267414

  6. Alcohol Drinking Pattern: A Comparison between HIV-Infected Patients and Individuals from the General Population

    PubMed Central

    Ikeda, Maria Leticia R.; Barcellos, Nemora T.; Alencastro, Paulo R.; Wolff, Fernando H.; Moreira, Leila B.; Gus, Miguel; Brandão, Ajacio B. M.; Fuchs, Flavio D.; Fuchs, Sandra C.

    2016-01-01

    Background Alcohol consumption is highly prevalent in the general population and among HIV-infected population. This study aimed to compare the pattern of alcohol consumption and to describe characteristics associated with heavy alcohol consumption in individuals from the general population with patients infected with HIV. Methods Participants for this analysis came from a population-based cross-sectional study and from a consecutive sampling of patients infected with HIV. Participants aged 18 years or older were interviewed using similar questionnaires with questions pertaining to socio-demographic characteristics, alcohol consumption, smoking, physical activity, and HIV-related characteristics, among others. Blood pressure and anthropometric measures were measured using standardized procedures. Results Weekly alcohol consumption was more prevalent among individuals from the general population than HIV-infected patients: 57.0 vs. 31.1%, P<0.001. The prevalence of heavy episodic drinking was higher in the population sample as well: 46.1 vs. 17.0%, P<0.001. In the general population, heavy alcohol consumption was more prevalent in men. Cigarette smoking was independently associated with heavy alcohol consumption among HIV infected (Prevalence Ratio; PR = 5.9; 95%CI 2.6–13.9; P<0,001) and general population (PR = 2.6; 95%CI 1.9–3.0; P<0.001). Years at school were inversely associated with heavy alcohol consumption among HIV-infected patients and directly associated among participants from the general population, even after controlling for sex, age, skin color, and smoking. Conclusions Heavy alcohol consumption is more prevalent in the general population than among HIV-infected patients. Individuals aware about their disease may reduce the amount of alcoholic beverages consumption comparatively to healthy individuals from the general population. PMID:27362541

  7. Generalizing in Interaction: Middle School Mathematics Students Making Mathematical Generalizations in a Population-Modeling Project

    ERIC Educational Resources Information Center

    Jurow, A. Susan

    2004-01-01

    Generalizing or making claims that extend beyond particular situations is a central mathematical practice and a focus of classroom mathematics instruction. This study examines how aspects of generality are produced through the situated activities of a group of middle school mathematics students working on an 8-week population-modeling project. The…

  8. General relativity and cosmic structure formation

    NASA Astrophysics Data System (ADS)

    Adamek, Julian; Daverio, David; Durrer, Ruth; Kunz, Martin

    2016-04-01

    Numerical simulations are a versatile tool for providing insight into the complicated process of structure formation in cosmology. This process is mainly governed by gravity, which is the dominant force on large scales. At present, a century after the formulation of general relativity, numerical codes for structure formation still employ Newton’s law of gravitation. This approximation relies on the two assumptions that gravitational fields are weak and that they originate from non-relativistic matter. Whereas the former seems well justified on cosmological scales, the latter imposes restrictions on the nature of the `dark’ components of the Universe (dark matter and dark energy), which are, however, poorly understood. Here we present the first simulations of cosmic structure formation using equations consistently derived from general relativity. We study in detail the small relativistic effects for a standard lambda cold dark matter cosmology that cannot be obtained within a purely Newtonian framework. Our particle-mesh N-body code computes all six degrees of freedom of the metric and consistently solves the geodesic equation for particles, taking into account the relativistic potentials and the frame-dragging force. This conceptually clean approach is very general and can be applied to various settings where the Newtonian approximation fails or becomes inaccurate, ranging from simulations of models with dynamical dark energy or warm/hot dark matter to core collapse supernova explosions.

  9. Drug test feasibility in a general population household survey.

    PubMed

    Fendrich, Michael; Johnson, Timothy P; Wislar, Joseph S; Hubbell, Amy

    2004-03-01

    Drug testing was used as an adjunct to a general population household drug use survey administered via audio computer assisted self-interview. Participants, ages 18-40 years residing in Chicago, were recruited to participate in three different biological tests (hair, oral fluid, and urine) presented in random order subsequent to completing an interview. Subjects had the option of participating in zero to three different tests. We examined participation/refusal in tests, reaction to testing requests, as well as variables associated with participation and reaction. Subjects were randomly assigned to a low (US$ 10 per test) or high (US$ 20 per test) incentive condition. Over 90% of the sample participated in at least one test, usually the oral fluid test. Associations between refusal status and two variables, socioeconomic status (SES) and presence of children in the household, provided partial support for the notion that drug test participation parallels the survey response process in general. Incentive level did not directly increase drug test participation. Reporting of recent illicit drug use was associated with participation in only one procedure, hair testing. Type of test offered and individual differences in willingness to be drug tested were important predictors of drug test refusal and subject reaction to testing requests. Compared with urine and hair testing, oral fluid testing had lower refusal rates and was generally more acceptable to respondents in a general population survey. The findings support the feasibility of incorporating multiple drug tests with modest incentives into general population household surveys on drug abuse. PMID:15036546

  10. Testing General Relativity with Atom Interferometry

    SciTech Connect

    Dimopoulos, Savas; Graham, Peter W.; Hogan, Jason M.; Kasevich, Mark A.

    2007-03-16

    The unprecedented precision of atom interferometry will soon lead to laboratory tests of general relativity to levels that will rival or exceed those reached by astrophysical observations. We propose such an experiment that will initially test the equivalence principle to 1 part in 10{sup 15} (300 times better than the current limit), and 1 part in 10{sup 17} in the future. It will also probe general relativistic effects--such as the nonlinear three-graviton coupling, the gravity of an atom's kinetic energy, and the falling of light--to several decimals. In contrast with astrophysical observations, laboratory tests can isolate these effects via their different functional dependence on experimental variables.

  11. Testing general relativity with atom interferometry.

    PubMed

    Dimopoulos, Savas; Graham, Peter W; Hogan, Jason M; Kasevich, Mark A

    2007-03-16

    The unprecedented precision of atom interferometry will soon lead to laboratory tests of general relativity to levels that will rival or exceed those reached by astrophysical observations. We propose such an experiment that will initially test the equivalence principle to 1 part in 10(15) (300 times better than the current limit), and 1 part in 10(17) in the future. It will also probe general relativistic effects - such as the nonlinear three-graviton coupling, the gravity of an atom's kinetic energy, and the falling of light - to several decimals. In contrast with astrophysical observations, laboratory tests can isolate these effects via their different functional dependence on experimental variables. PMID:17501039

  12. Weakly coupled gravity beyond general relativity

    NASA Astrophysics Data System (ADS)

    Camanho, Xián O.; Edelstein, José D.; Zhiboedov, Alexander

    2015-11-01

    We explore four-dimensional (4D) weakly coupled gravity beyond general relativity in an on-shell language, focusing on the graviton three-point vertex. This admits a novel structure which can be attributed to a term cubic in the Riemann tensor. We consider a generalization of the Shapiro time delay experiment that involves polarized gravitons and show that the new vertex leads to causality violation. Fixing the problem demands the inclusion of an infinite tower of massive higher spin states. Perturbative string theory provides an example of this phenomenon, the only known so far. Interestingly enough, the same argument being applied to inflation suggests that stringy signatures may be hidden in the non-Gaussianities of the primordial gravity wave spectrum.

  13. General Relativity Theory: Tests through Time

    NASA Astrophysics Data System (ADS)

    Yatskiv, Ya. S.; Alexandrov, A. N.; Vavilova, I. B.; Zhdanov, V. I.; Kudrya, Yu. N.; Parnovsky, S. L.; Fedorova, E.V .; Khmil, S. V.

    2006-08-01

    Theoretical basis of the General Relativity theory (GR), its experimental tests as well as GR applications were briefly summarized in the new textbook devoted to the World Year of Physics-2005 (authors - Yatskiv Ya.S., Alexandrov A.N., Vavilova I.B., Zhdanov V.I., Kudrya Yu.N., Parnovsky S.L., Fedorova E.V., Khmil S.V., Kyiv:Akademperiodika, 2005, 288 p.). The monograph addresses scientists, post-graduate students, and students specialized in the natural sciences as well as everyone who takes a great interest in GR. Special attention is paid on Relativistic Reference Systems, as an attachment to this book, including attachment to this book where the Resolution of the XXIV IAU General Assembly is given (in Ukrainian).

  14. On the Geodesic Hypothesis in General Relativity

    NASA Astrophysics Data System (ADS)

    Yang, Shiwu

    2014-02-01

    In this paper, we give a rigorous derivation of Einstein's geodesic hypothesis in general relativity. We use small material bodies governed by the nonlinear Klein-Gordon equations to approximate the test particle. Given a vacuum spacetime , we consider the initial value problem for the Einstein-scalar field system. For all sufficiently small ɛ and δ ≤ ɛ q , q > 1, where δ, ɛ are the amplitude and size of the particle, we show the existence of the solution to the Einstein-scalar field system with the property that the energy of the particle is concentrated along a timelike geodesic. Moreover, the gravitational field produced by is negligibly small in C 1, that is, the spacetime metric g is C 1 close to the given vacuum metric h. These results generalize those obtained by Stuart in (Ann Sci École Norm Sup (4) 37(2):312-362, 2004, J Math Pures Appl (9) 83(5):541-587, 2004).

  15. Generally Covariant Hamiltonian Approach to the Generalized Harmonic Formulation of General Relativity

    NASA Astrophysics Data System (ADS)

    Cao, Meng

    The goal of this dissertation is to develop a generally covariant Hamiltonian approach to the generalized harmonic formulation of general relativity. As en route investigations, an important class of coordinate transformations in the context of the 3 + 1 decomposition, foliation preserving transformations, is defined; transformation rules of various 3 + 1 decomposition variables under this change of coordinates are investigated; the notion of covariant time derivative under foliation preserving transformations is defined; gauge conditions of various numerical relativity formulations are rewritten in generally covariant form. The Hamiltonian formulation of the generalized harmonic system is defined in the latter part of this dissertation. With the knowledge of covariant time derivative, the Hamiltonian formulation is extended to achieve general covariance. The Hamiltonian formulation is further proved to be symmetric hyperbolic.

  16. New Area Law in General Relativity.

    PubMed

    Bousso, Raphael; Engelhardt, Netta

    2015-08-21

    We report a new area law in general relativity. A future holographic screen is a hypersurface foliated by marginally trapped surfaces. We show that their area increases monotonically along the foliation. Future holographic screens can easily be found in collapsing stars and near a big crunch. Past holographic screens exist in any expanding universe and obey a similar theorem, yielding the first rigorous area law in big bang cosmology. Unlike event horizons, these objects can be identified at finite time and without reference to an asymptotic boundary. The Bousso bound is not used, but it naturally suggests a thermodynamic interpretation of our result. PMID:26340179

  17. New Area Law in General Relativity

    NASA Astrophysics Data System (ADS)

    Bousso, Raphael; Engelhardt, Netta

    2015-08-01

    We report a new area law in general relativity. A future holographic screen is a hypersurface foliated by marginally trapped surfaces. We show that their area increases monotonically along the foliation. Future holographic screens can easily be found in collapsing stars and near a big crunch. Past holographic screens exist in any expanding universe and obey a similar theorem, yielding the first rigorous area law in big bang cosmology. Unlike event horizons, these objects can be identified at finite time and without reference to an asymptotic boundary. The Bousso bound is not used, but it naturally suggests a thermodynamic interpretation of our result.

  18. Mesh and measure in early general relativity

    NASA Astrophysics Data System (ADS)

    Darrigol, Olivier

    2015-11-01

    In the early days of general relativity, several of Einstein's readers misunderstood the role of coordinates or "mesh-system" in ways that threatened the basic predictions of the theory. This confusion largely derived from intrinsic defects of Einstein's first systematic exposition of his theory. A few of Einstein's followers, including Arthur Eddington, Hermann Weyl, and Max von Laue, identified the interpretive difficulties and solved them by combining a deeply geometrical understanding of the theory with detailed attention to the concrete conditions of measurement.

  19. Epicycles and Poincare resonances in general relativity

    SciTech Connect

    Koekoek, G.; Holten, J. W. van

    2011-03-15

    The method of geodesic deviations provides analytic approximations to geodesics in arbitrary background space-times. As such the method is a useful tool in many practical situations. In this paper we construct an improved parametrized version of the method, and discuss some subtleties in its application related to secular motions in first as well as in higher-order. In particular we work out the general second-order contribution to bound orbits in Schwarzschild space-time and show that it provides very good analytical results all the way up to the innermost stable circular orbit.

  20. Generalized nonholonomic mechanics, servomechanisms and related brackets

    NASA Astrophysics Data System (ADS)

    Cendra, H.; Grillo, S.

    2006-02-01

    It is well known that nonholonomic systems obeying D'Alembert's principle are described on the Hamiltonian side, after using the Legendre transformation, by the so-called almost-Poisson brackets. In this paper we define the Lagrangian and Hamiltonian sides of a class of generalized nonholonomic systems (GNHS), obeying a generalized version of D'Alembert's principle, such as rubber wheels (like some simplified models of pneumatic tires) and certain servomechanisms (like the controlled inverted pendulum), and show that corresponding equations of motion can also be described in terms of a bracket. We present essentially all possible brackets in terms of which the mentioned equations can be written down, which include the brackets that appear in the literature, and point out those (if any) that are naturally related to each system. In particular, we show there always exists a Leibniz bracket related to a GNHS, and conversely, that every Leibniz system is a GNHS. The control of the inverted pendulum on a cart is studied as an illustrative example.

  1. Genetic Determinants of Pubertal Timing in the General Population

    PubMed Central

    Gajdos, Zofia K.Z.; Henderson, Katherine D.; Hirschhorn, Joel N.

    2010-01-01

    Puberty is an important developmental stage during which reproductive capacity is attained. The timing of puberty varies greatly among healthy individuals in the general population and is influenced by both genetic and environmental factors. Although genetic variation is known to influence the normal spectrum of pubertal timing, the specific genes involved remain largely unknown. Genetic analyses have identified a number of genes responsible for rare disorders of pubertal timing such as hypogonadotropic hypogonadism and Kallmann syndrome. Recently, the first loci with common variation reproducibly associated with population variation in the timing of puberty were identified at 6q21 in or near LIN28B and at 9q31.2. However, these two loci explain only a small fraction of the genetic contribution to population variation in pubertal timing, suggesting the need to continue to consider other loci and other types of variants. Here we provide an update of the genes implicated in disorders of puberty, discuss genes and pathways that may be involved in the timing of normal puberty, and suggest additional avenues of investigation to identify genetic regulators of puberty in the general population. PMID:20144687

  2. Predictors for mortality from respiratory failure in a general population

    PubMed Central

    Kobayashi, Maki; Shibata, Yoko; Inoue, Sumito; Igarashi, Akira; Sato, Kento; Sato, Masamichi; Nemoto, Takako; Abe, Yuki; Nunomiya, Keiko; Nishiwaki, Michiko; Tokairin, Yoshikane; Kimura, Tomomi; Daimon, Makoto; Makino, Naohiko; Watanabe, Tetsu; Konta, Tsuneo; Ueno, Yoshiyuki; Kato, Takeo; Kayama, Takamasa; Kubota, Isao

    2016-01-01

    Risk factors for death from respiratory failure in the general population are not established. The aim of this study was to determine the characteristics of individuals who die of respiratory failure in a Japanese general population. In total, 3253 adults aged 40 years or older participated in annual health check in Takahata, Yamagata, Japan from 2004 to 2006. Subject deaths through the end of 2010 were reviewed; 27 subjects died of respiratory failure (pneumonia, n = 22; COPD, n = 1; pulmonary fibrosis, n = 3; and bronchial asthma, n = 1). Cox proportional hazard analysis revealed that male sex; higher age, high levels of D-dimer and fibrinogen; lower body mass index (BMI) and total cholesterol; and history of stroke and gastric ulcer were independent risk factors for respiratory death. On analysis with C-statistics, net reclassification improvement, and integrated discrimination improvement, addition of the disease history and laboratory data significantly improved the model prediction for respiratory death using age and BMI. In conclusion, we identified risk factors for mortality from respiratory failure in a prospective cohort of a Japanese general population. Men who were older, underweight, hypocholesterolemic, hypercoagulo-fibrinolytic, and had a history of stroke or gastric ulcer had a higher risk of mortality due to respiratory failure. PMID:27180927

  3. Predictors for mortality from respiratory failure in a general population.

    PubMed

    Kobayashi, Maki; Shibata, Yoko; Inoue, Sumito; Igarashi, Akira; Sato, Kento; Sato, Masamichi; Nemoto, Takako; Abe, Yuki; Nunomiya, Keiko; Nishiwaki, Michiko; Tokairin, Yoshikane; Kimura, Tomomi; Daimon, Makoto; Makino, Naohiko; Watanabe, Tetsu; Konta, Tsuneo; Ueno, Yoshiyuki; Kato, Takeo; Kayama, Takamasa; Kubota, Isao

    2016-01-01

    Risk factors for death from respiratory failure in the general population are not established. The aim of this study was to determine the characteristics of individuals who die of respiratory failure in a Japanese general population. In total, 3253 adults aged 40 years or older participated in annual health check in Takahata, Yamagata, Japan from 2004 to 2006. Subject deaths through the end of 2010 were reviewed; 27 subjects died of respiratory failure (pneumonia, n = 22; COPD, n = 1; pulmonary fibrosis, n = 3; and bronchial asthma, n = 1). Cox proportional hazard analysis revealed that male sex; higher age, high levels of D-dimer and fibrinogen; lower body mass index (BMI) and total cholesterol; and history of stroke and gastric ulcer were independent risk factors for respiratory death. On analysis with C-statistics, net reclassification improvement, and integrated discrimination improvement, addition of the disease history and laboratory data significantly improved the model prediction for respiratory death using age and BMI. In conclusion, we identified risk factors for mortality from respiratory failure in a prospective cohort of a Japanese general population. Men who were older, underweight, hypocholesterolemic, hypercoagulo-fibrinolytic, and had a history of stroke or gastric ulcer had a higher risk of mortality due to respiratory failure. PMID:27180927

  4. General Relativity: an Einstein Centenary Survey

    NASA Astrophysics Data System (ADS)

    Hawking, Stephen; Israel, W.

    2010-03-01

    List of contributors; Preface; 1. An introductory survey S. W. Hawking and W. Israel; 2. The confrontation between gravitation theory and experiment C. M. Will; 3. Gravitational-radiation experiments D. H. Douglass and V. B. Braginsky; 4. The initial value problem and the dynamical formulation of general relativity A. E. Fischer and J. E. Marsden; 5. Global structure of spacetimes R. Geroch and G. T. Horowitz; 6. The general theory of the mechanical, electromagnetic and thermodynamic properties of black holes B. Carter; 7. An introduction to the theory of the Kerr metric and its peturbations S. Chandrasekhar; 8. Black hole astrophysics R. D. Blandford and K. S. Thorne; 9. The big bang cosmology - enigmas and nostrums R. H. Dicke and P. J. E. Peebles; 10. Cosmology and the early universe Ya B. Zel'dovitch; 11. Anisotropic and inhomogeneous relativistic cosmologies M. A. H. MacCallum; 12. Singularities and time-asymmetry R. Penrose; 13. Quantum field theory in curved spacetime G. W. Gibbons; 14. Quantum gravity: the new synthesis B. S. DeWitt; 15. The path-integral approach to quantum gravity S. W. Hawking; 16. Ultraviolet divergences in quantum theories of gravitation S. Weinberg; References; Index.

  5. Motivations for antigravity in General Relativity

    NASA Astrophysics Data System (ADS)

    Chardin, G.

    1997-08-01

    We present arguments showing that it is natural to interpret the negative mass part of the Kerr solution as representing the geometry experienced by antimatter. The C, P and T discrete transformations are considered for this geometry. The C and T properties of the proposed identification are found to be in agreement with the usual representation of antimatter. In addition, we conjecture a property of perfect stigmatism through Kerr wormholes which allows General Relativity to mimic antigravity. Kerr wormholes would then act as “supermirrors” reversing the C, P and T images of an object seen through it. This interpretation is subject to several experimental tests and able to provide an explanation, without any free parameter, of the “CP” violation observed in the neutral kaon system.

  6. On thick domain walls in general relativity

    NASA Technical Reports Server (NTRS)

    Goetz, Guenter; Noetzold, Dirk

    1989-01-01

    Planar scalar field configurations in general relativity differ considerably from those in flat space. It is shown that static domain walls of finite thickness in curved space-time do not possess a reflection symmetry. At infinity, the space-time tends to the Taub vacuum on one side of the wall and to the Minkowski vacuum (Rindler space-time) on the other. Massive test particles are always accelerated towards the Minkowski side, i.e., domain walls are attractive on the Taub side, but repulsive on the Minkowski side (Taub-vacuum cleaner). It is also proved that the pressure in all directions is always negative. Finally, a brief comment is made concerning the possibility of infinite, i.e., bigger than horizon size, domain walls in our universe. All of the results are independent of the form of the potential V(phi) greater than or equal to 0 of the scalar field phi.

  7. Rapidly rotating polytropes in general relativity

    NASA Technical Reports Server (NTRS)

    Cook, Gregory B.; Shapiro, Stuart L.; Teukolsky, Saul A.

    1994-01-01

    We construct an extensive set of equilibrium sequences of rotating polytropes in general relativity. We determine a number of important physical parameters of such stars, including maximum mass and maximum spin rate. The stability of the configurations against quasi-radial perturbations is diagnosed. Two classes of evolutionary sequences of fixed rest mass and entropy are explored: normal sequences which behave very much like Newtonian evolutionary sequences, and supramassive sequences which exist solely because of relativistic effects. Dissipation leading to loss of angular momentum causes a star to evolve in a quasi-stationary fashion along an evolutionary sequence. Supramassive sequences evolve towards eventual catastrophic collapse to a black hole. Prior to collapse, the star must spin up as it loses angular momentum, an effect which may provide an observational precursor to gravitational collapse to a black hole.

  8. The confrontation between general relativity and experiment

    NASA Technical Reports Server (NTRS)

    Will, C. M.

    1980-01-01

    Experiments that test the foundations of gravitation theory in terms of the Einstein equivalence principle are discussed along with solar system tests of general relativity at the post-Newtonian level. These include classical (light-deflection, time delay and perihelion shift) tests as well as tests of the strong equivalence principle. The binary pulsar is discussed as an extra-solar-system gravitational testing ground, and attention is given to the multipolarity of the waves and the amount of radiation damping. The mass function, periastron shift, redshift-Doppler parameter and rate of change of the orbit period (Pb) of the binary pulsar are also considered, and it is suggested that the measurement of Pb represents the first observation of the effects of gravitational radiation.

  9. Spherical shock waves in general relativity

    SciTech Connect

    Nutku, Y. )

    1991-11-15

    We present the metric appropriate to a spherical shock wave in the framework of general relativity. This is a Petrov type-{ital N} vacuum solution of the Einstein field equations where the metric is continuous across the shock and the Riemann tensor suffers a step-function discontinuity. Spherical gravitational waves are described by type-{ital N} Robinson-Trautman metrics. However, for shock waves the Robinson-Trautman solutions are unacceptable because the metric becomes discontinuous in the Robinson-Trautman coordinate system. Other coordinate systems that have so far been introduced for describing Robinson-Trautman solutions also suffer from the same defect. We shall present the {ital C}{sup 0}-form of the metric appropriate to spherical shock waves using Penrose's approach of identification with warp. Further extensions of Penrose's method yield accelerating, as well as coupled electromagnetic-gravitational shock-wave solutions.

  10. Unique Diagnostic of Magneto Optical Trap Relative Populations

    NASA Astrophysics Data System (ADS)

    Brédy, Richard; Nguyen, Hai; Camp, Howard A.; Wilson, Kyle M.; Awata, Takaaki; Depaola, Brett D.

    2003-05-01

    In the studies of population trapping, electromagnetically induced transparency, and other processes associated with coherent excitation, knowledge of excited state populations can provide greatly needed insights. However, methodologies often used to determine relative populations in laser-excited system often rely on a model-dependent measurement. Furthermore, lasers used to probe the system can modify the very system one wishes to make measurements on. An accurate, non-intrusive and perusing method has been developed to circumvent this problem. MOTRIMS (Magneto Optical Trap Recoil Ion Momentum Spectroscopy) uses charge transfer as a non-intrusive probe of temporal evolution of excited state fraction, in particular the 5p of Rb. The generalization of these measurements to more complicated systems, e.g. a Rubidium sample having mixture of 5s, 5p, 4d, and Rydberg states will be presented.

  11. General relativity from a thermodynamic perspective

    NASA Astrophysics Data System (ADS)

    Padmanabhan, T.

    2014-03-01

    I show that the gravitational dynamics in a bulk region of space can be connected to a thermodynamic description in the boundary of that region, thereby providing clear physical interpretations of several mathematical features of classical general relativity: (1) The Noether charge contained in a bulk region, associated with a specific time evolution vector field, has a direct thermodynamic interpretation as the gravitational heat content of the boundary surface. (2) This result, in turn, shows that all static spacetimes maintain holographic equipartition in the following sense: In these spacetimes, the number of degrees of freedom in the boundary is equal to the number of degrees of freedom in the bulk. (3) In a general, evolving spacetime, the rate of change of gravitational momentum is related to the difference between the number of bulk and boundary degrees of freedom. It is this departure from the holographic equipartition which drives the time evolution of the spacetime. (4) When the equations of motion hold, the (naturally defined) total energy of the gravity plus matter within a bulk region, will be equal to the boundary heat content. (5) After motivating the need for an alternate description of gravity (if we have to solve the cosmological constant problem), I describe a thermodynamic variational principle based on null surfaces to achieve this goal. The concept of gravitational heat density of the null surfaces arises naturally from the Noether charge associated with the null congruence. The variational principle, in fact, extremises the total heat content of the matter plus gravity system. Several variations on this theme and implications are described.

  12. [Representations and attitudes toward cancer in the French general population].

    PubMed

    Beck, François; Gautier, Arnaud; Guilbert, Philippe; Peretti-Watel, Patrick

    2009-05-01

    Cancer has become a major public health issue. It is thus crucial to measure the general population's behaviours, opinions and perceptions about cancer and its associated risk factors. This article describes some of the main findings of a 2005 French survey (n = 4,046). Cancer is considered by a large majority to be the most serious disease, far before HIV/AIDS and cardiovascular diseases. The carcinogenic risk that is associated to main risk factors, such as sun exposure, tobacco-smoking and alcohol use appears to be well-known. However, many people justify dangerous behaviours with strongly-anchored beliefs, which maintain dangerous behaviours for health on the long-term. What's more, the perception of risk proliferation can also generate risk denial. Because self-exempting beliefs are still widespread within the general opinion, it is essential to continue public health information campaigns dedicated to cancer prevention, so as to induce better prevention practices within the general population and to reduce stigmatisation and isolation experienced by cancer patients. If risk denial is not systematically a consequence of a lack of information, it is generally associated to a cognitive construction that gives coherence to behaviours. PMID:19480836

  13. CKD Prevalence Varies across the European General Population.

    PubMed

    Brück, Katharina; Stel, Vianda S; Gambaro, Giovanni; Hallan, Stein; Völzke, Henry; Ärnlöv, Johan; Kastarinen, Mika; Guessous, Idris; Vinhas, José; Stengel, Bénédicte; Brenner, Hermann; Chudek, Jerzy; Romundstad, Solfrid; Tomson, Charles; Gonzalez, Alfonso Otero; Bello, Aminu K; Ferrieres, Jean; Palmieri, Luigi; Browne, Gemma; Capuano, Vincenzo; Van Biesen, Wim; Zoccali, Carmine; Gansevoort, Ron; Navis, Gerjan; Rothenbacher, Dietrich; Ferraro, Pietro Manuel; Nitsch, Dorothea; Wanner, Christoph; Jager, Kitty J

    2016-07-01

    CKD prevalence estimation is central to CKD management and prevention planning at the population level. This study estimated CKD prevalence in the European adult general population and investigated international variation in CKD prevalence by age, sex, and presence of diabetes, hypertension, and obesity. We collected data from 19 general-population studies from 13 European countries. CKD stages 1-5 was defined as eGFR<60 ml/min per 1.73 m(2), as calculated by the CKD-Epidemiology Collaboration equation, or albuminuria >30 mg/g, and CKD stages 3-5 was defined as eGFR<60 ml/min per 1.73 m(2) CKD prevalence was age- and sex-standardized to the population of the 27 Member States of the European Union (EU27). We found considerable differences in both CKD stages 1-5 and CKD stages 3-5 prevalence across European study populations. The adjusted CKD stages 1-5 prevalence varied between 3.31% (95% confidence interval [95% CI], 3.30% to 3.33%) in Norway and 17.3% (95% CI, 16.5% to 18.1%) in northeast Germany. The adjusted CKD stages 3-5 prevalence varied between 1.0% (95% CI, 0.7% to 1.3%) in central Italy and 5.9% (95% CI, 5.2% to 6.6%) in northeast Germany. The variation in CKD prevalence stratified by diabetes, hypertension, and obesity status followed the same pattern as the overall prevalence. In conclusion, this large-scale attempt to carefully characterize CKD prevalence in Europe identified substantial variation in CKD prevalence that appears to be due to factors other than the prevalence of diabetes, hypertension, and obesity. PMID:26701975

  14. A general theory of quantum relativity

    NASA Astrophysics Data System (ADS)

    Minic, Djordje; Tze, Chia-Hsiung

    2004-02-01

    The geometric form of standard quantum mechanics is compatible with the two postulates: (1) the laws of physics are invariant under the choice of experimental setup and (2) every quantum observation or event is intrinsically statistical. These postulates remain compatible within a background independent extension of quantum theory with a local intrinsic time implying the relativity of the concept of a quantum event. In this extension the space of quantum events becomes dynamical and only individual quantum events make sense observationally. At the core of such a general theory of quantum relativity is the three-way interplay between the symplectic form, the dynamical metric and non-integrable almost complex structure of the space of quantum events. Such a formulation provides a missing conceptual ingredient in the search for a background independent quantum theory of gravity and matter. The crucial new technical element in our scheme derives from a set of recent mathematical results on certain infinite-dimensional almost Kahler manifolds which replace the complex projective spaces of standard quantum mechanics.

  15. An Introduction to General Relativity and Cosmology

    NASA Astrophysics Data System (ADS)

    Plebanski, Jerzy; Krasinski, Andrzej

    2006-08-01

    1. How the theory of relativity came into being (a brief historical sketch); Part I. Elements of Differential Geometry: 2. A short sketch of two-dimensional differential geometries; 3. Tensors, tensor densities; 4. Covariant derivatives; 5. Parallel transport and geodesic lines; 6. Curvature of a manifold: flat manifolds; 7. Riemannian geometry; 8. Symmetries of Rieman spaces, invariance of tensors; 9. Methods to calculate the curvature quickly - Cartan forms and algebraic computer programs; 10. The spatially homogeneous Bianchi-type spacetimes; 11. The Petrov classification by the spinor method; Part II. The Gravitation Theory: 12. The Einstein equations and the sources of a gravitational field; 13. The Maxwell and Einstein-Maxwell equations and the Kaluza-Klein theory; 14. Spherically symmetric gravitational field of isolated objects; 15. Relativistic hydrodynamics and thermodynamics; 16. Relativistic cosmology I: general geometry; 17. Relativistic cosmology II: the Robertson-Walker geometry; 18. Relativistic cosmology III: the Lemaître-Tolman geometry; 19. Relativistic cosmology IV: generalisations of L-T and related geometries; 20. The Kerr solution; 21. Subjects omitted in this book; References.

  16. An Introduction to General Relativity and Cosmology

    NASA Astrophysics Data System (ADS)

    Plebanski, Jerzy; Krasinski, Andrzej

    2012-09-01

    1. How the theory of relativity came into being (a brief historical sketch); Part I. Elements of Differential Geometry: 2. A short sketch of two-dimensional differential geometries; 3. Tensors, tensor densities; 4. Covariant derivatives; 5. Parallel transport and geodesic lines; 6. Curvature of a manifold: flat manifolds; 7. Riemannian geometry; 8. Symmetries of Rieman spaces, invariance of tensors; 9. Methods to calculate the curvature quickly - Cartan forms and algebraic computer programs; 10. The spatially homogeneous Bianchi-type spacetimes; 11. The Petrov classification by the spinor method; Part II. The Gravitation Theory: 12. The Einstein equations and the sources of a gravitational field; 13. The Maxwell and Einstein-Maxwell equations and the Kaluza-Klein theory; 14. Spherically symmetric gravitational field of isolated objects; 15. Relativistic hydrodynamics and thermodynamics; 16. Relativistic cosmology I: general geometry; 17. Relativistic cosmology II: the Robertson-Walker geometry; 18. Relativistic cosmology III: the Lemaître-Tolman geometry; 19. Relativistic cosmology IV: generalisations of L-T and related geometries; 20. The Kerr solution; 21. Subjects omitted in this book; References.

  17. BOOK REVIEW: Modern Canonical Quantum General Relativity

    NASA Astrophysics Data System (ADS)

    Kiefer, Claus

    2008-06-01

    The open problem of constructing a consistent and experimentally tested quantum theory of the gravitational field has its place at the heart of fundamental physics. The main approaches can be roughly divided into two classes: either one seeks a unified quantum framework of all interactions or one starts with a direct quantization of general relativity. In the first class, string theory (M-theory) is the only known example. In the second class, one can make an additional methodological distinction: while covariant approaches such as path-integral quantization use the four-dimensional metric as an essential ingredient of their formalism, canonical approaches start with a foliation of spacetime into spacelike hypersurfaces in order to arrive at a Hamiltonian formulation. The present book is devoted to one of the canonical approaches—loop quantum gravity. It is named modern canonical quantum general relativity by the author because it uses connections and holonomies as central variables, which are analogous to the variables used in Yang Mills theories. In fact, the canonically conjugate variables are a holonomy of a connection and the flux of a non-Abelian electric field. This has to be contrasted with the older geometrodynamical approach in which the metric of three-dimensional space and the second fundamental form are the fundamental entities, an approach which is still actively being pursued. It is the author's ambition to present loop quantum gravity in a way in which every step is formulated in a mathematically rigorous form. In his own words: 'loop quantum gravity is an attempt to construct a mathematically rigorous, background-independent, non-perturbative quantum field theory of Lorentzian general relativity and all known matter in four spacetime dimensions, not more and not less'. The formal Leitmotiv of loop quantum gravity is background independence. Non-gravitational theories are usually quantized on a given non-dynamical background. In contrast, due to

  18. Generalized Entropic Uncertainty Relations with Tsallis' Entropy

    NASA Technical Reports Server (NTRS)

    Portesi, M.; Plastino, A.

    1996-01-01

    A generalization of the entropic formulation of the Uncertainty Principle of Quantum Mechanics is considered with the introduction of the q-entropies recently proposed by Tsallis. The concomitant generalized measure is illustrated for the case of phase and number operators in quantum optics. Interesting results are obtained when making use of q-entropies as the basis for constructing generalized entropic uncertainty measures.

  19. Directions in General Relativity, Vol. 2

    NASA Astrophysics Data System (ADS)

    Hu, B. L.; Jacobson, T. A.

    2005-10-01

    Preface; Dieter Brill: a spacetime perspective; 1. Thawing the frozen formalism: the difference between observables and what we observe A. Anderson; 2. Jacobi's action and the density of states J. D. Brown and J. W. York; 3. Decoherence of correlation histories E. Calzetta and B. L. Hu; 4. The initial value problem in light of Ashtekar's variables R. Capovilla, J. Dell and T. Jacobson; 5. Status report on an axiomatic basis for functional integration P. Cartier and C. DeWitt-Morette; 6. Solution of the coupled Einstein constraints on asymptotically Euclidean manifolds Y. Choquet-Bruhat; 7. Compact Cauchy horizons and Cauchy surfaces P. Chrusciel and J. Isenberg; 8. The classical electron J. M. Cohen and E. Mustafa; 9. Gauge (in)variance, mass and parity in D=3 revisited S. Deser; 10. Triality, exceptional Lie groups and Dirac operators F. Flaherty; 11. The reduction of the state vector and limitations on measurement in the quantum mechanics of closed systems J. B. Hartle; 12 Quantum linearization instabilities of de Sitter spacetime A. Higuchi; 13. What is the true description of charged black holes? G. T. Horowitz; 14. Limits on the adiabatic index in static stellar models L. Lindblom and A. K. M. Masood-ul-Alam; 15. On the relativity of rotation B. Mashhoon; 16. Recent progress and open problems in linearization stability V. E. Moncrief; 17. Brill waves N. Murchadha; 18. You can't get there from here: constraints on topology change K. Schleich and D. M. Witt; 19. Time, measurement and information loss in quantum cosmology L. Smolin; 20. Impossible measurements on quantum fields R. Sorkin; 21. A new condition implying the existence of a constant mean curvature foliation F. J. Tipler; 22. Maximal slices in stationary spacetimes with ergoregions R. M. Wald; 23. (1 + 1) - Dimensional methods for general relativity J. H. Yoon; 24. Coalescence of primal gravity waves to make cosmological mass without matter D. E. Holz, W. A. Miller, M. Wakano and J. A. Wheeler

  20. Exotic differentiable structures and general relativity

    NASA Astrophysics Data System (ADS)

    Brans, Carl H.; Randall, Duane

    1993-02-01

    We review recent developments in differential topology with special concern for their possible significance to physical theories, especially general relativity. In particular we are concerned here with the discovery of the existence of non-standard (“fake” or “exotic”) differentiable structures on topologically simple manifolds such asS 7, ℝ4 andS 3 X ℝ1. Because of the technical difficulties involved in the smooth case, we begin with an easily understood toy example looking at the role which the choice of complex structures plays in the formulation of two-dimensional vacuum electrostatics. We then briefly review the mathematical formalisms involved with differentiable structures on topological manifolds, diffeomorphisms and their significance for physics. We summarize the important work of Milnor, Freedman, Donaldson, and others in developing exotic differentiable structures on well known topological manifolds. Finally, we discuss some of the geometric implications of these results and propose some conjectures on possible physical implications of these new manifolds which have never before been considered as physical models.

  1. Harmonizing General Relativity with Quantum Mechanics

    NASA Astrophysics Data System (ADS)

    Alfonso-Faus, Antonio

    2007-04-01

    Gravitation is the common underlying texture between General Relativity and Quantum Mechanics. We take gravitation as the link that can make possible the marriage between these two sciences. We use here the duality of Nature for gravitation: A continuous warped space, wave-like, and a discrete quantum gas, particle-like, both coexistent and producing an equilibrium state in the Universe. The result is a static, non expanding, spherical, unlimited and finite Universe, with no cosmological constant and no dark energy. Macht's Principle is reproduced here by the convergence of the two cosmological equations of Einstein. From this a Mass Boom concept is born given by M = t, M the mass of the Universe and t its age. Also a decreasing speed of light is the consequence of the Mass Boom, c = 1/t, which explains the Supernovae Type Ia observations without the need of expansion (nor, of course, accelerated expansion). Our Mass Boom model completely wipes out the problems and paradoxes built in the Big Bang model, like the horizon, monopole, entropy, flatness, fine tuning, etc. It also eliminates the need for inflation.

  2. Generalized Spearman estimators of relative dose.

    PubMed

    Morton, R

    1981-06-01

    In a biological assay the expected response may be transformed to a variable bounded between 0 and 1. If the transformed response is regarded as analogous to the tolerance distribution function, the mean of that distribution may be estimated for the standard and test preparations, and a simple estimator of the relative potency obtained. The special case where the identity transformation is used for a quantal response corresponds to Spearman's estimator, and our generalization has similar unbiasedness properties to that estimator. Asymptotic results are derived when the intervals between dose levels decrease and the sample of each dose level simultaneously increases. These results are evaluated for the case with equal sample sizes at regularly spaced values of the dose metameter. An approximate test for similarity is proposed. If the tolerance distribution is known up to a scale parameter, then the transformation may be chosen so that the estimator is asymptotically fully efficient. An application to the thermal disinfestation of wheat is given. PMID:7272411

  3. Tardive and spontaneous dyskinesia incidence in the general population

    PubMed Central

    2013-01-01

    Background To identify the incidence rate of spontaneous dyskinesia (SD) and tardive dyskinesia (TD) in a general population and to examine the association between dykinesia and potential risk factors (exposure to metoclopramide [MCP], antipsychotic drugs, and history of diabetes and psychoses). Methods A retrospective cohort study was conducted for the years 2001 through 2010, based on medical claims data from the Deseret Mutual Benefit Administrators (DMBA). Results Thirty-four cases of TD and 229 cases of SD were identified. The incidence rate of TD among persons previously prescribed an antipsychotic or metoclopramide (MCP) (per 1,000) was 4.6 (1.6-7.7) for those with antipsychotic drug use only, 8.5 (4.8-12.2) for those with MCP use only, and 15.0 (2.0-28.1) for those with both antipsychotic and MCP use. In the general population, the incidence rate (per 100,000 person-years) of TD was 4.3 and of probable SD was 28.7. The incidence rates of TD and SD increased with age and were greater for females. Those with diabetes or psychoses had almost a 3-fold greater risk of TD than those without either of these diseases. Persons with schizophrenia had 31.2 times increased risk of TD than those without the disease. Positive associations also existed between the selected diseases and the incidence rate of probable SD, with persons with schizophrenia having 4.4 times greater risk of SD than those without the disease. Conclusions SD and TD are rare in this general population. Diabetes, psychoses, and especially schizophrenia are positively associated with SD and TD. A higher proportion of those with SD present with spasm of the eyelid muscles (blepharospasm) compared more with the TD cases who present more with orofacial muscular problems. PMID:23714238

  4. The Concept of General Relativity is not Related to Reality

    NASA Astrophysics Data System (ADS)

    Kotas, Ronald

    2015-04-01

    The concept of general relativity is not related to reality. It is not real or factual Science. GR cannot account for objects falling to earth or for the weight of objects sitting on the earth. The Cavendish demonstration showing the attraction between two masses at right angles to earth's gravity, is not explained by GR. No one can prove the existence of ``space fabric.'' The concept of ``space time'' effects causing gravitational attraction between masses is wrong. Conservation law of energy - momentum does not exist in GR. LIGO fails in detecting ``gravity waves'' because there is no ``space fabric'' to transmit them. The Gravity B Probe data manipulated to show some effects, is not proof of ``space fabric.'' It is Nuclear Quantum Gravitation that provides clear definitive explanation of Gravity and Gravitation. It is harmonious with Newtonian and Quantum Mechanics, and Scientific Logic. Nuclear Quantum Gravitation has 10 clear, Scientific proofs and 21 more good indications. With this theory the Physical Forces are Unified. See: OBSCURANTISM ON EINSTEIN GRAVITATION? http://www.santilli-foundation.org/inconsistencies-gravitation.php and Einstein's Theory of Relativity versus Classical Mechanics, by Paul Marmet http://www.newtonphysics.on.ca/einstein/

  5. Diagnosis, evaluation, and treatment of lead poisoning in general population.

    PubMed

    D'souza, Herman Sunil; Dsouza, Sebestina Anita; Menezes, Geraldine; Venkatesh, Thuppil

    2011-04-01

    Among the heavy metals, lead still remains the major toxic pollutant of the environment. Human exposure to lead can occur through numerous pathways including air, food, dust, soil, and water. In the present study 14 lead poisoned patients with non-occupational lead exposure were evaluated. They were followed up and compared against the controls with no history of lead exposure. The patients had high blood lead levels and symptoms of weakness, dizziness, abdominal pain, generalized body ache, loss of appetite, and anxiety. Repeated course of chelation therapy helped to bring down their body burden of lead. Alternative sources for lead exposure can cause severe lead poisoning in general population. Screening and medical management of such individuals is very important to identify and eliminate sources of lead. The treatment and management requires a thorough medical evaluation and environmental intervention. PMID:22468050

  6. [Daytime consequences of insomnia complaints in the French general population].

    PubMed

    Ohayon, M M; Lemoine, P

    2004-01-01

    Insomnia is a frequent symptom in the general population; numerous studies have proven this. In the past years, classifications have gradually given more emphasis to daytime repercussions of insomnia and to their consequences on social and cognitive functioning. They are now integrated in the definition of insomnia and are used to quantify its severity. If the daytime consequences of insomnia are well known at the clinical level, there are few epidemiological data on this matter. The aim of this study was to assess the daytime repercussions of insomnia complaints in the general population of France. A representative sample (n=5,622) aged 15 or older was surveyed by telephone with the help of the sleep-EVAL expert system, a computer program specially designed to evaluate sleep disorders and to manage epidemiological investigations. Interviews have been completed for 80.8% of the solicited subjects (n=5,622). The variables considered comprised insomnia and its daytime repercussions on cognitive functioning, affective tone, daytime sleepiness and diurnal fatigue. Insomnia was found in 18.6% of the sample. The prevalence was higher in women (22.4%) than in men (14.5%, p<0.001) with a relative risk of 1.7 (95% confidence interval 1.5 to 2) and was twice more frequent for subjects 65 years of age or older compared to subjects younger than 45 years. Approximately 30% of subjects reporting insomnia had difficulties initiating sleep. Nearly 75% of insomnia complainers reported having a disrupted sleep or waking up too early in the morning and about 40% said they had a non-restorative sleep. Repercussions on daytime functioning were reported by most insomnia subjects (67%). Repercussions on cognitive functioning changed according age, number of insomnia symptoms and the use of a psychotropic medication. A decreased efficiency was more likely to be reported by subjects between 15 and 44 years of age (OR: 2.9), those using a psychotropic (OR: 1.5), those reporting at least

  7. Gamma and Related Functions Generalized for Sequences

    ERIC Educational Resources Information Center

    Ollerton, R. L.

    2008-01-01

    Given a sequence g[subscript k] greater than 0, the "g-factorial" product [big product][superscript k] [subscript i=1] g[subscript i] is extended from integer k to real x by generalizing properties of the gamma function [Gamma](x). The Euler-Mascheroni constant [gamma] and the beta and zeta functions are also generalized. Specific examples include…

  8. Jumping to conclusions and paranoid ideation in the general population.

    PubMed

    Freeman, Daniel; Pugh, Katherine; Garety, Philippa

    2008-07-01

    An association of a 'jumping to conclusions' (JTC) reasoning style and delusions has been repeatedly found. The data-gathering bias has been particularly implicated with higher levels of delusional conviction in schizophrenia. For the first time the symptom, psychological and social correlates of jumping to conclusions are examined in a large general population sample. This is based upon the recognition that delusional ideation in non-clinical populations is on a continuum of severity with delusions in psychosis. Two hundred individuals completed a probabilistic reasoning task and assessments of paranoid ideation, intellectual functioning, affective symptoms, anomalies of experience, cognitive flexibility, illicit drug use, social support, and trauma. The jumping to conclusions reasoning bias was found in 20% of the non-clinical sample. JTC was strongly associated with higher levels of conviction in paranoid thoughts and the occurrence of perceptual anomalies, but not with the presence of affective symptoms. The results indicate that jumping to conclusions is a reasoning bias specifically associated with levels of delusional conviction, and is not a product of generally high levels of distress and affect. The association of jumping to conclusions with the types of anomalies of experience seen in psychotic disorders is intriguing, and consistent with recent dopamine dysregulation theories and the importance of reasoning to perception. The study is a further illustration of the need to consider the dimensions of delusional experience separately. PMID:18442898

  9. High prevalence of celiac disease in Italian general population.

    PubMed

    Volta, U; Bellentani, S; Bianchi, F B; Brandi, G; De Franceschi, L; Miglioli, L; Granito, A; Balli, F; Tiribelli, C

    2001-07-01

    The worldwide increase of celiac disease prompted us to assess its prevalence in the Italian general population. The 3483 inhabitants of Campogalliano were tested for immunoglobulin A anti-endomysial antibodies. Twenty subjects showed antibody positivity and duodenal biopsy detected typical mucosal lesions of celiac disease in 17 of them; the remaining three cases had a normal villous architecture, but the finding of increased gamma/delta intraepithelial lymphocytes in all and the heterodimer DQA1*0501, DQB1*0201 in two of them was consistent with potential celiac disease. Only one patient had an overt malabsorption syndrome, characterized by diarrhea, weight loss, and severe weakness. In eight subjects atypical symptoms of celiac disease, such as dyspepsia and depression, were present, whereas the remaining subjects were silent. Celiac disease was more frequent in younger age groups. Our cross-sectional design study demonstrates that celiac disease prevalence in the Italian general population is 4.9 per 1000 (95% CI 2.8-7.8), increasing up to 5.7 per 1000 (95% CI 3.5-8.8) with the inclusion of potential cases. PMID:11478502

  10. Recruiting Gamblers from the General Population for Research Purposes: Outcomes from Two Contrasting Approaches

    ERIC Educational Resources Information Center

    Williams, Jeremy D.; Pulford, Justin; Bellringer, Maria; Abbott, Max

    2010-01-01

    Multiple means exist by which gamblers including problem gamblers may be recruited from the general population for research survey purposes. However, there appears to be limited discussion in the published literature about the relative merits of one or other approach. This paper addresses this gap, in part, by reporting the experiences of…

  11. General Population Norms about Child Abuse and Neglect and Associations with Childhood Experiences

    ERIC Educational Resources Information Center

    Bensley, L.; Ruggles, D.; Simmons, K.W.; Harris, C.; Williams, K.; Putvin, T.; Allen, M.

    2004-01-01

    Background:: A variety of definitions of child abuse and neglect exist. However, little is known about norms in the general population as to what constitutes child abuse and neglect or how perceived norms may be related to personal experiences. Methods:: We conducted a random-digit-dialed telephone survey of 504 Washington State adults.…

  12. Prevalence of Chronic Medical Conditions in Adults with Mental Retardation: Comparison with the General Population.

    ERIC Educational Resources Information Center

    Kapell, Deborah; Nightingale, Beryle; Rodriguez, Ana; Lee, Joseph H.; Zigman, Warren B.; Schupf, Nicole

    1998-01-01

    A study interviewed caregivers and reviewed medical records of 278 adults with mental retardation with and without Down syndrome. The adults with mental retardation had age-related disorders comparable to those in the general population, but there was an increased frequency of thyroid disorders, nonischemic heart disorders, and sensory impairment.…

  13. Intimate Partner Violence in the U.S. General Population: Progress and Future Directions

    ERIC Educational Resources Information Center

    Field, Craig A.; Caetano, Raul

    2005-01-01

    This article reviews survey research on intimate partner violence (IPV) in the U.S. general population. Results from survey research conducted over the past quarter century are briefly summarized. Three additional national studies related to injuries, crime victimization, and homicide among intimate partners in the United States are also…

  14. Anti-HCV prevalence in the general population of Lithuania

    PubMed Central

    Liakina, Valentina; Valantinas, Jonas

    2012-01-01

    Summary Background The aim of this study was to assess risk factors for HCV acquisition and prevalence of anti-HCV in the general population of Lithuania. Material/Methods The study enrolled 1528 randomly selected adults from the 5 biggest cities of Lithuania and its rural regions. Screening for anti-HCV was performed by analysis of peripheral capillary blood with lateral flow immunochromatography and confirmation of positive cases by peripheral venous blood testing with 2-step chemiluminescent microparticle immunoassay. Results Anti-HCV prevalence in Lithuania is 2.78% and according to the standard European population the adjusted anti-HCV rate is 2.85%. It is more prevalent among men (crude rates: 4.02% males vs. 1.49% females, p=.0030) and this does not depend on age. Vilnius and Kaunas regions have higher infection rates than smaller rural regions (2.92% and 3.01% vs. 2.24%, 0.74% and 1.35%). Nowadays among our population HCV infection spreads mainly via intravenous drug use (OR=42.5, p<.0001). HCV transmission occurs through blood transfusions (OR=6.4, p=.0002), tooth removal (OR=4.1, p=.0048), childbirth (OR=5.0, p=.0224), multiple and a long-term hospitalization (OR=3.0, p=.0064), tattooing (OR=4.4, p=.0013), open traumas (OR=3.7, p=.0009) and intrafamilially (OR=11.3, p=.0002). Conclusions 2.78% of the population is anti-HCV-positive. The anti-HCV rate is higher in Vilnius and Kaunas in comparison with other regions. HCV spreads mainly through intravenous drug use, but intrafamilial and some nosocomial routes are also important. The anti-HCV prevalence did not depend on age. Despite active prevention of nosocomial HCV transmission, the incidence of HCV infection does not decrease due to virus spread mostly in “trusted networks” of intravenous drug users. PMID:22367136

  15. General Relativity, Scalar Fields and Cosmic Strings.

    NASA Astrophysics Data System (ADS)

    Burd, Adrian Benedict

    1987-09-01

    Available from UMI in association with The British Library. This thesis is divided into three, essentially self-contained, parts. In the first part we examine the structure of classical three-dimensional space-times. Here, we review and extend what is known about the gravitational theories in these models. We investigate the non-existence of a Newtonian limit to the relativistic theories showing that in the presence of certain matter terms, Newtonian gravity can be obtained as a suitable weak-field limit. We present a number of new, exact static and non-static solutions to the equations of three-dimensional general relativity with scalar field and perfect fluid sources. We comment on the relationship between the stiff perfect fluid and the scalar field. Motivated by the Kaluza-Klein procedure of dimensional reduction we find some exact scalar field solutions which have analogues in four-dimensions. We also present classification schemes based on the group of motions of homogeneous space-times and on the Cotton -York tensor. The description of the general cosmological solution in the vicinity of the singularity is given in terms of the number of arbitrary spatial functions independently specified on a space-like hypersurface. We also study a series approximation to the space-time in the vicinity of the cosmological singularity. Some conjectures are made concerning the space-time singularities. We present two exact cosmological solutions containing self-interacting scalar fields. The models exhibit an inflationary behaviour. We also present an anisotropic cosmological model. The second part of the thesis contains a study of certain cosmological models which have self-interacting scalar fields obeying an exponential potential. We use the techniques of phase portrait analysis to study the N-dimensional cosmological models as well as certain anisotropic models. The latter involves the analysis of a three-dimensional system of equations and we review the relevant theory

  16. Standardization of a screening instrument (PHQ-15) for somatization syndromes in the general population

    PubMed Central

    2013-01-01

    Background The PHQ-15 is widely used as an open access screening instrument for somatization syndromes in different health care settings, thus far, normative data from the general population are not available. The objectives of the study were to generate normative data and to further investigate the construct validity of the PHQ-15 in the general population. Methods Nationally representative face-to face household surveys were conducted in Germany between 2003 and 2008 (n=5,031). The survey questionnaires included, the 15-item somatization module from the Patient Health Questionnaire (PHQ-15), the 9-item depression module (PHQ-9), the Satisfaction With Life Scale (SWLS), the SF-12 for the measurement of health related quality of life, and demographic characteristics. Results Normative data for the PHQ-15 were generated for both genders and different age levels including 5031 subjects (53.6% female) with a mean age (SD) of 48.9 (18.1) years. Somatization syndromes occured in 9.3% of the general population. Women had significantly higher mean (SD) scores compared with men [4.3 (4.1) vs. 3.4 (4.0)]. Intercorrelations with somatization were highest with depression, followed by the physical component summary scale of health related quality of life. Conclusions The normative data provide a framework for the interpretation and comparisons of somatization syndromes with other populations. Evidence supports reliability and validity of the PHQ-15 as a measure of somatization syndromes in the general population. PMID:23514436

  17. The value of a college degree for foster care alumni: comparisons with general population samples.

    PubMed

    Salazar, Amy M

    2013-04-01

    Higher education is associated with substantial adult life benefits, including higher income and improved quality of life, among others. The current study compared adult outcomes of 250 foster care alumni college graduates with two samples of general population graduates to explore the role higher education plays in these young adults' lives. Outcomes compared include employment, income, housing, public assistance, physical and mental health, happiness, and other outcomes that are often found to be related to educational attainment. Foster care alumni college graduates were very similar to general population college graduates for individual income and rate of employment. However, foster care alumni graduates were behind general population graduates on factors such as self-reported job security, household earnings, health, mental health, financial satisfaction, home ownership, happiness, and public assistance usage. Results have implications for policy and practice regarding the most effective means of supporting postcollege stability of youths with foster care experience. PMID:23724577

  18. Reliability, Validity and Factor Structure of the 12-Item General Health Questionnaire among General Population

    PubMed Central

    Petkovska, Miodraga Stefanovska; Bojadziev, Marjan I.; Stefanovska, Vesna Velikj

    2015-01-01

    AIM: The aim of the study is to analyze the internal consistency; validity and factor structure of the twelve item General Health Questionnaire for the Macedonian general population. MATERIAL AND METHODS: Data came from nationally representative sample of 1603 randomly selected Macedonians all aged 18 years or older. RESULTS: The mean GHQ score in the general sample was found to be 7.9 (SD = 4.3). The results revealed a higher GHQ score among women (M = 8.91, SD = 4.5) compared to men (M = 6.89; SD = 4.2). The participants from the rural areas obtained a lower GHQ score (M = 7.55, SD = 3.8) compared to participants coming from the urban areas (M = 9.37, SD = 4.1). The principal component analysis with oblique rotation (direct oblimin) with maximum likelihood procedure solution was performed and the results yielded a three factor solution which jointly accounted for 57.17% of the total variance: Factor I named social management (items 1, 3, 4, 6, 7 and 8); Factor II stress (items 2, 5 and 9) and Factor III named self-confidence (items 10, 11 and 12). Its factor structure is in line with representative research from other population groups. CONCLUSION: The GHQ-12 can be used effectively for assessment of the overall psychological well-being and detection of non-psychotic psychiatric problems among the Macedonian population.

  19. Prevalence of Titin Truncating Variants in General Population

    PubMed Central

    Akinrinade, Oyediran; Koskenvuo, Juha W.; Alastalo, Tero-Pekka

    2015-01-01

    Background Truncating titin (TTN) mutations, especially in A-band region, represent the most common cause of dilated cardiomyopathy (DCM). Clinical interpretation of these variants can be challenging, as these variants are also present in reference populations. We carried out systematic analyses of TTN truncating variants (TTNtv) in publicly available reference populations, including, for the first time, data from Exome Aggregation Consortium (ExAC). The goal was to establish more accurate estimate of prevalence of different TTNtv to allow better clinical interpretation of these findings. Methods and Results Using data from 1000 Genomes Project, Exome Sequencing Project (ESP) and ExAC, we estimated the prevalence of TTNtv in the population. In the three population datasets, 52–54% of TTNtv were not affecting all TTN transcripts. The frequency of truncations affecting all transcripts in ExAC was 0.36% (0.32% - 0.41%, 95% CI) and 0.19% (0.16% - 0.23%, 95% CI) for those affecting the A-band. In the A-band region, the prevalences of frameshift, nonsense and essential splice site variants were 0.057%, 0.090%, and 0.047% respectively. Cga/Tga (arginine/nonsense–R/*) transitional change at CpG mutation hotspots was the most frequent type of TTN nonsense mutation accounting for 91.3% (21/23) of arginine residue nonsense mutation (R/*) at TTN A-band region. Non-essential splice-site variants had significantly lower proportion of private variants and higher proportion of low-frequency variants compared to essential splice-site variants (P = 0.01; P = 5.1 X 10−4, respectively). Conclusion A-band TTNtv are more rare in the general population than previously reported. Based on this analysis, one in 500 carries a truncation in TTN A-band suggesting the penetrance of these potentially harmful variants is still poorly understood, and some of these variants do not manifest as autosomal dominant DCM. This calls for caution when interpreting TTNtv in individuals and families

  20. Polypharmacy in older adults with human immunodeficiency virus infection compared with the general population

    PubMed Central

    Gimeno-Gracia, Mercedes; Crusells-Canales, María José; Armesto-Gómez, Francisco Javier; Compaired-Turlán, Vicente; Rabanaque-Hernández, María José

    2016-01-01

    Background The percentage of older HIV-positive patients is growing, with an increase in age-related comorbidities and concomitant medication. Objectives To quantify polypharmacy and profile types of non-antiretroviral drugs collected at community pharmacies in 2014 by HIV-positive individuals on antiretroviral therapy and to compare these findings with those of the general population. Methods HIV-positive patients (n=199) were compared with a group of patients from the general population (n=8,172), aged between 50 and 64 years. The factors compared were prevalence of polypharmacy (≥5 comedications with cumulative defined daily dose [DDD] per drug over 180), percentage of patients who collected each therapeutic class of drug, and median duration for each drug class (based on DDD). Results were stratified by sex. Results Polypharmacy was more common in HIV-positive males than in the male general population (8.9% vs 4.4%, P=0.010). Polypharmacy was also higher in HIV-positive females than in the female general population (11.3% vs 3.4%, P=0.002). Percentage of HIV-positive patients receiving analgesics, anti-infectives, gastrointestinal drugs, central nervous system (CNS) agents, and respiratory drugs was higher than in the general population, with significant differences between male populations. No differences were observed in proportion of patients receiving cardiovascular drugs. The estimated number of treatment days (median DDDs) were higher in HIV-positive males than in males from the general population for anti-infectives (32.2 vs 20.0, P<0.001) and CNS agents (238.7 vs 120.0, P=0.002). A higher percentage of HIV-positive males than males from the general population received sulfonamides (17.1% vs 1.5%, P<0.001), macrolides (37.1% vs 24.9%, P=0.020), and quinolones (34.3% vs 21.2%, P=0.009). Conclusion Polypharmacy is more common in HIV-positive older males and females than in similarly aged members of the general population. HIV-positive patients received

  1. Body image and weight consciousness among South Asian, Italian and general population women in Britain.

    PubMed

    Bush, H M; Williams, R G; Lean, M E; Anderson, A S

    2001-12-01

    Italians in Britain have low rates of coronary heart disease while South Asians have high rates, which correspond to a tendency to central abdominal fat deposition and overweight. World variations in attitudes to body size are thought to be related to economic security. This cross-sectional study employed a range of measures including photographic silhouettes of known BMI to investigate the attitudes of 259 South Asian, Italian and general population women (aged 20-42 years) towards body size. Migrants are compared with British-born minority members. Our results indicate that although migrant South Asians were less happy with their weight than migrant Italians, fewer had tried to lose weight in the past or had experienced external pressures to change their bodies. More migrant South Asians than Italians or general population women equated one of the four largest shapes (BMI 28-38) with health and successful reproduction. All groups wanted to resemble one of the two thinnest shapes, equating them with longevity, likelihood of marriage and job success. British-born South Asians generally showed a considerable degree of convergence towards general population women's negative attitudes to large body size, but British-born Italians' attitudes were significantly more negative even than general population women. The study's conclusions were that South Asian health beliefs are an important focus of resistance to slimness. The tendency of migrant South Asians to equate large size with health contrasts with the opposing views of Italian and general population women. British-born South Asians' views are modifying from those of migrants, but significant differences remain when compared with general population women and British-born Italians. Present differences in economic security offer only a partial explanation; South Asian attitudes may be explained by economic insecurity in the past. PMID:11895321

  2. An Elementary Formalism for General Relativity.

    ERIC Educational Resources Information Center

    diSessa, Andrea A.

    1981-01-01

    An elementary formalism is developed for representing curved space-time which allows transparent qualitative explanation of general relativistic effects and is used to make a conceptual analysis of Einstein's principle of equivalence. A final section outlines a number of student activities. (Author/SK)

  3. The dystrophin gene and cognitive function in the general population

    PubMed Central

    Vojinovic, Dina; Adams, Hieab HH; van der Lee, Sven J; Ibrahim-Verbaas, Carla A; Brouwer, Rutger; van den Hout, Mirjam CGN; Oole, Edwin; van Rooij, Jeroen; Uitterlinden, Andre; Hofman, Albert; van IJcken, Wilfred FJ; Aartsma-Rus, Annemieke; van Ommen, GertJan B; Ikram, M Arfan; van Duijn, Cornelia M; Amin, Najaf

    2015-01-01

    The aim of our study is to investigate whether single-nucleotide dystrophin gene (DMD) variants associate with variability in cognitive functions in healthy populations. The study included 1240 participants from the Erasmus Rucphen family (ERF) study and 1464 individuals from the Rotterdam Study (RS). The participants whose exomes were sequenced and who were assessed for various cognitive traits were included in the analysis. To determine the association between DMD variants and cognitive ability, linear (mixed) modeling with adjustment for age, sex and education was used. Moreover, Sequence Kernel Association Test (SKAT) was used to test the overall association of the rare genetic variants present in the DMD with cognitive traits. Although no DMD variant surpassed the prespecified significance threshold (P<1 × 10−4), rs147546024:A>G showed strong association (β=1.786, P-value=2.56 × 10−4) with block-design test in the ERF study, while another variant rs1800273:G>A showed suggestive association (β=−0.465, P-value=0.002) with Mini-Mental State Examination test in the RS. Both variants are highly conserved, although rs147546024:A>G is an intronic variant, whereas rs1800273:G>A is a missense variant in the DMD which has a predicted damaging effect on the protein. Further gene-based analysis of DMD revealed suggestive association (P-values=0.087 and 0.074) with general cognitive ability in both cohorts. In conclusion, both single variant and gene-based analyses suggest the existence of variants in the DMD which may affect cognitive functioning in the general populations. PMID:25227141

  4. Impulsivity in the general population: A national study

    PubMed Central

    Chamorro, Jaime; Bernardi, Silvia; Potenza, Marc N.; Grant, Jon E.; Marsh, Rachel; Wang, Shuai; Blanco, Carlos

    2013-01-01

    Objective The construct of impulsivity is an important determinant of personality differences, psychiatric disorders, and associated risk-taking behaviors. Most existing knowledge about impulsivity comes from clinical samples. To date, no study has estimated the prevalence of impulsivity and examined its correlates in the general population. Method We analyzed data from a large national sample of the United States population. Face-to-face surveys of 34 653 adults aged 18 years and older residing in households were conducted during the 2004–2005 period. Diagnoses of mood, anxiety, and drug disorders as well as personality disorders were based on the Alcohol Use Disorder and Associated Disabilities Interview Schedule—DSM-IV Version. Results Impulsivity was common (17% of the sample), particularly among males and younger individuals, and associated with a broad range of axis I and II disorders, particularly drug dependence, cluster B, dependent and schizotypal personality disorders, bipolar disorder and ADHD. It was associated with behavioral disinhibition, attention deficits, and lack of planning. Individuals with impulsivity were more likely to engage in behaviors that could be dangerous to themselves or others, including driving recklessly, starting fights, shoplifting, perpetrating domestic violence and trying to hurt or kill themselves. They were exposed to higher risk of lifetime trauma and to substantial physical and psychosocial impairment. Conclusion Given the association of impulsivity with psychiatric disorders and multiple adverse events, there is a need to target impulsivity in prevention and treatment efforts. PMID:22626529

  5. Latex allergy: a relevant issue in the general pediatric population.

    PubMed

    Lee, M H; Kim, K T

    1998-01-01

    Although latex allergy is a widely recognized problem of the pediatric myelomeningocele population and of frequent users of latex products, it is often overlooked in the general pediatric population. The prevalence of latex in common household items and in medical environments increases one's exposure and thus one's possibility of sensitization to latex. Latex allergy may range from mild local reactions such as erythema to more severe systemic reactions such as asthma or anaphylaxis. The immunoglobulin E-mediated mechanism of these reactions has been confirmed serologically by the presence of latex-specific immunoglobulin E with radioallergosorbent testing. Because avoidance of latex is currently the only way to prevent reactions, the identification of household items that contain latex is extremely important. However, because inadvertent exposure to latex is not uncommon, Medic-Alert bracelets and an Epi-Pen should be provided for children allergic to latex. Pediatric nurses should consider latex allergy as a possible diagnosis in situations of unexplained allergic or anaphylactic reactions and should be aware of optimal therapeutic interventions. PMID:9987254

  6. Nationwide HIV prevalence survey in general population in Niger.

    PubMed

    Boisier, P; Ouwe Missi Oukem-Boyer, O N; Amadou Hamidou, A; Sidikou, F; Ibrahim, M L; Elhaj Mahamane, A; Mamadou, S; Sanda Aksenenkova, T; Hama Modibo, B; Chanteau, S; Sani, A; Louboutin-Croc, J-P

    2004-11-01

    A national population-based survey was carried out in Niger in 2002 to assess HIV prevalence in the population aged 15-49 years. A two-stage cluster sampling was used and the blood specimens were collected on filter paper and tested according to an algorithm involving up to three diagnostic tests whenever appropriate. Testing was unlinked and anonymous. The refusal rate was 1.1% and 6056 blood samples were available for analysis. The adjusted prevalence of HIV was 0.87% (95% CI, 0.5-1.3%) and the 95% CI of the estimated number of infected individuals was 22 864-59 640. HIV-1 and HIV-2 represented, respectively, 95.6% and 2.9% of infections while dual infections represented 1.5%. HIV positivity rate was 1.0% in women and 0.7% in men. It was significantly higher among urban populations than among rural ones (respectively, 2.1% and 0.6%, P < 10(-6)). Using logistic regression, the variables significantly related to the risk of being tested positive for HIV were urban housing, increasing age and being either widowed or divorced. The estimate from the national survey was lower than the prevalence assessed from antenatal clinic data (2.8% in 2001). In the future, the representativeness of sentinel sites should be improved by increasing the representation of rural areas accounting for more than 80% of the population. Compared with other sub-Saharan countries, the HIV prevalence in Niger is still moderate. This situation represents a strong argument for enhancing prevention programmes and makes realistic the projects promoting an access to potent antiretroviral therapies for the majority. PMID:15548311

  7. Enterobius vermicularis infection among population of General Mansilla, Argentina

    PubMed Central

    Pezzani, Betina C; Minvielle, Marta C; de Luca, María M; Córdoba, María A; Apezteguía, María C; Basualdo, Juan A

    2004-01-01

    AIM: To evaluate the relationships between the personal, sociocultural, and environmental characteristics, and the presence or absence of symptoms with the detection of Enterobius vermicularis (E. vermicularis) in a population sample in our region (General Mansilla, Province of Buenos Aires, Argentina), by individual and familiar analyses. METHODS: E. vermicularis was diagnosed in 309 people from 70 family units residing in the urban area and the rural area of the city of General Mansilla. Each of them was surveyed so as to register personal, environmental and sociocultural data. Questions about the presence or absence of anal itch, abdominal pain and sleeping disorder were also asked. Significant associations were determined by square chi tests. Logistic regression models were adjusted by using a backward conditional stepwise method to determine the presence of this parasite in the individuals and in the families. RESULTS: The parasites were found in 29.12% (90/309) of the individuals, with a frequency of 14.28% (20/140) among the heads of the families and of 41.42% (70/169) among the children. The only variables showing a significant association were affiliation, where the risk category was "being the son/daughter of", and the symptoms were abdominal pain, sleeping disorder, and anal itch. Families with a member infected with parasite were considered Positive Families (PF) and they were 40/70 (57.14%), only 5% (2/40) of the PF had 100% of their members infected with the parasite. The logistic regression models applied showed that the risk categories were mainly affiliation (son/daughter) and housing (satisfactory) among others. CONCLUSION: The presence of E. vermicularis was proved in one third of the studied population. The frequency of families with all their members infected with the parasite was very low. Most of the studied personal, sociocultural, and environmental variables did not turn out to be significantly associated with the presence of the parasite

  8. Validation of the standardised assessment of personality – abbreviated scale in a general population sample

    PubMed Central

    Seegobin, Seth; Frissa, Souci; Hatch, Stephani L.; Hotopf, Matthew; Hayes, Richard D.; Moran, Paul

    2015-01-01

    Abstract Background Personality disorder (PD) is associated with important health outcomes in the general population. However, the length of diagnostic interviews poses a significant barrier to obtaining large scale, population‐based data on PD. A brief screen for the identification of people at high risk of PD in the general population could be extremely valuable for both clinicians and researchers. Aim We set out to validate the Standardised Assessment of Personality – Abbreviated Scale (SAPAS), in a general population sample, using the Structured Clinical Interviews for DSM‐IV Personality Disorders (SCID‐II) as a gold standard. Method One hundred and ten randomly selected, community‐dwelling adults were administered the SAPAS screening interview. The SCID‐II was subsequently administered by a clinical interviewer blind to the initial SAPAS score. Receiver operating characteristic analysis was used to assess the discriminatory performance of the SAPAS, relative to the SCID‐II. Results Area under the curve for the SAPAS was 0.70 (95% CI = 0.60 to 0.80; p < 0.001), indicating moderate overall discriminatory accuracy. A cut point score of 4 on the SAPAS correctly classified 58% of participants. At this cut point, the sensitivity and specificity were 0.69 and 0.53 respectively. Conclusion The SAPAS operates less efficiently as a screen in general population samples and is probably most usefully applied in clinical populations. © 2015 The Authors Personality and Mental Health published by John Wiley & Sons Ltd PMID:26314385

  9. Life Expectancy in Police Officers: A Comparison with the U.S. General Population

    PubMed Central

    Violanti, John M.; Hartley, Tara A.; Gu, Ja K.; Fekedulegn, Desta; Andrew, Michael E.; Burchfiel, Cecil M.

    2016-01-01

    Previous epidemiological research indicates that police officers have an elevated risk of death relative to the general population overall and for several specific causes. Despite the increased risk for mortality found in previous research, controversy still exists over the life expectancy of police officers. The goal of the present study was to compare life expectancy of male police officers from Buffalo New York with the U.S. general male population utilizing an abridged life table method. On average, the life expectancy of Buffalo police officers in our sample was significantly lower than the U.S. population (mean difference in life expectancy =21.9 years; 95% CI: 14.5-29.3; p<0.0001). Life expectancy of police officers was shorter and differences were more pronounced in younger age categories. Additionally, police officers had a significantly higher average probability of death than did males in the general population (mean difference= 0.40; 95% CI: 0.26,-0.54; p<0.0001). The years of potential life lost (YPLL) for police officers was 21 times larger than that of the general population (Buffalo male officers vs. U.S. males = 21.7, 95% CI: 5.8-37.7). Possible reasons for shorter life expectancy among police are discussed, including stress, shift work, obesity, and hazardous environmental work exposures. PMID:24707585

  10. Uncertainty relations for general phase spaces

    NASA Astrophysics Data System (ADS)

    Werner, Reinhard F.

    2016-04-01

    We describe a setup for obtaining uncertainty relations for arbitrary pairs of observables related by a Fourier transform. The physical examples discussed here are the standard position and momentum, number and angle, finite qudit systems, and strings of qubits for quantum information applications. The uncertainty relations allow for an arbitrary choice of metric for the outcome distance, and the choice of an exponent distinguishing, e.g., absolute and root mean square deviations. The emphasis of this article is on developing a unified treatment, in which one observable takes on values in an arbitrary locally compact Abelian group and the other in the dual group. In all cases, the phase space symmetry implies the equality of measurement and preparation uncertainty bounds. There is also a straightforward method for determining the optimal bounds.

  11. Gastroesophageal reflux disease symptoms in the Greek general population: prevalence and risk factors

    PubMed Central

    Spantideas, Nikolaos; Drosou, Eirini; Bougea, Anastasia; Assimakopoulos, Dimitrios

    2016-01-01

    Background and aims Population-based data regarding the prevalence of gastroesophageal reflux disease (GERD) in Greece are very poor. This study estimated the prevalence of GERD symptoms and their risk factors in the Greek adult population. Methods A self-administered questionnaire was answered by a randomly selected population of 340 subjects. The question regarding “heartburn, chest pain, indigestion, or stomach acid coming up” as included in the Reflux Symptom Index was used for prevalence assessment. Results The monthly prevalence of GERD symptoms was found to be 52.0% in the Greek general population, with no statistically significant difference between the two sexes (P>0.05). The age group of 65–79 years showed a higher prevalence rate of GERD. Symptom severity was found to be mild (59.3%) or moderate (27.1%). The number of cigarettes smoked daily (but not smoking duration) as well as the number of alcoholic drinks consumed daily (but not the duration of alcohol drinking) were found to be related to GERD symptoms. No reported concomitant disease or medication was found to be related with GERD symptoms. Conclusion The prevalence of GERD symptoms in the Greek general population was found to be 52.0%. Tobacco smoking and alcohol drinking but not concomitant disease or medications were found to be related with GERD symptoms. PMID:27382324

  12. Evaluating preference assessments for use in the general education population.

    PubMed

    Resetar, Jennifer L; Noell, George H

    2008-01-01

    This study compared the effectiveness of a multiple-stimulus-without-replacement (MSWO) preference assessment and teacher preference ranking in identifying reinforcers for use in a general education setting with typically developing elementary-school children. The mean number of digits correctly answered was greater in the MSWO-selected reward and the teacher-selected reward conditions relative to the no-reward condition for 2 of the 4 participants, but there were no differences between the MSWO-selected and teacher-selected reward conditions for any participant. PMID:18816985

  13. Evaluating Preference Assessments for Use in the General Education Population

    PubMed Central

    Resetar, Jennifer L; Noell, George H

    2008-01-01

    This study compared the effectiveness of a multiple-stimulus-without-replacement (MSWO) preference assessment and teacher preference ranking in identifying reinforcers for use in a general education setting with typically developing elementary-school children. The mean number of digits correctly answered was greater in the MSWO-selected reward and the teacher-selected reward conditions relative to the no-reward condition for 2 of the 4 participants, but there were no differences between the MSWO-selected and teacher-selected reward conditions for any participant. PMID:18816985

  14. Connection between Newtonian simulations and general relativity

    SciTech Connect

    Chisari, Nora Elisa; Zaldarriaga, Matias

    2011-06-15

    On large scales, comparable to the horizon, the observable clustering properties of galaxies are affected by various general relativistic effects. To calculate these effects one needs to consistently solve for the metric, densities, and velocities in a specific coordinate system or gauge. The method of choice for simulating large-scale structure is numerical N-body simulations which are performed in the Newtonian limit. Even though one might worry that the use of the Newtonian approximation would make it impossible to use these simulations to compute properties on very large scales, we show that the simulations are still solving the dynamics correctly even for long modes and we give formulas to obtain the position of particles in the conformal Newtonian gauge given the positions computed in the simulation. We also give formulas to convert from the output coordinates of N-body simulations to the observable coordinates of the particles.

  15. BOOK REVIEW: Advanced Mechanics and General Relativity Advanced Mechanics and General Relativity

    NASA Astrophysics Data System (ADS)

    Louko, Jorma

    2011-04-01

    Joel Franklin's textbook `Advanced Mechanics and General Relativity' comprises two partially overlapping, partially complementary introductory paths into general relativity at advanced undergraduate level. Path I starts with the Lagrangian and Hamiltonian formulations of Newtonian point particle motion, emphasising the action principle and the connection between symmetries and conservation laws. The concepts are then adapted to point particle motion in Minkowski space, introducing Lorentz transformations as symmetries of the action. There follows a focused development of tensor calculus, parallel transport and curvature, using examples from Newtonian mechanics and special relativity, culminating in the field equations of general relativity. The Schwarzschild solution is analysed, including a detailed discussion of the tidal forces on a radially infalling observer. Basics of gravitational radiation are examined, highlighting the similarities to and differences from electromagnetic radiation. The final topics in Path I are equatorial geodesics in Kerr and the motion of a relativistic string in Minkowski space. Path II starts by introducing scalar field theory on Minkowski space as a limit of point masses connected by springs, emphasising the action principle, conservation laws and the energy-momentum tensor. The action principle for electromagnetism is introduced, and the coupling of electromagnetism to a complex scalar field is developed in a detailed and pedagogical fashion. A free symmetric second-rank tensor field on Minkowski space is introduced, and the action principle of general relativity is recovered from coupling the second-rank tensor to its own energy-momentum tensor. Path II then merges with Path I and, supplanted with judicious early selections from Path I, can proceed to the Schwarzschild solution. The choice of material in each path is logical and focused. A notable example in Path I is that Lorentz transformations in Minkowki space are introduced

  16. The tau lepton in general relativity

    SciTech Connect

    Nienart, L.

    1988-01-01

    This dissertation presents the results of an investigation into trying to see how the mass of the tau lepton can arise from general Relativistic considerations. The formalism was applied earlier to electrons and predicted both the electron's mass and the muon's mass. The tau leptons mass will be found by considering the contribution of a non-zero magnetic moment to the quaternion fields and the spin affine connection fields in a Riemannian space. The exact mass operator is constructed from these fields, and is then approximated in 3 different ways in order to permit calculation. The expectation value of these approximations to the mass operator is then found, using the relativistic Coulomb wavefunctions. The choice of Coulomb states is due to the consideration that the pairs that comprise the vacuum in this field theory couple to the magnetic moment of the core electron in a manner resembling that of the electrons in the Hydrogen atom. As the coupling the author is considering in his model is that of magnetic dipole by design, an argument is presented in which the Coulombic coupling strength parameters of the Coulomb states are scaled in order to provide a suitable description of the magnetic states which the author is actually interested in. The resulting values for the mass of the tau lepton are then within half an order of magnitude of the experimental values.

  17. Action principle combining electromagnetism and general relativity

    SciTech Connect

    Moyer, H.G.

    1987-03-01

    The stationary action problem for a single, classical, point particle in external gravitational and electromagnetic fields is written in optimal control format. The relativistic interval is the independent variable and time, space, and action are the five dependent variables. A general metric is used for the space-time manifold so that the equations are manifestly covariant. The form of the system equations guarantees that the particle moves with unit speed with respect to interval. The Lagrangian is a function of the metric tensor and the electromagnetic four-potential, but not of particle parameters such as electric charge q and mass m. The Hamiltonian is not identically zero, unlike those derived in many earlier analyses. A constant of the motion is found that is identified with q/mc/sup 2/. An explanation is presented for the classical inequality mgreater than or equal to0. The trajectories can reduce to geodesics and even further to those governed by Fermat's principle of stationary time.

  18. General very special relativity is Finsler geometry

    SciTech Connect

    Gibbons, G. W.; Gomis, Joaquim; Pope, C. N.

    2007-10-15

    We ask whether Cohen and Glashow's very special relativity model for Lorentz violation might be modified, perhaps by quantum corrections, possibly producing a curved space-time with a cosmological constant. We show that its symmetry group ISIM(2) does admit a 2-parameter family of continuous deformations, but none of these give rise to noncommutative translations analogous to those of the de Sitter deformation of the Poincare group: space-time remains flat. Only a 1-parameter family DISIM{sub b}(2) of deformations of SIM(2) is physically acceptable. Since this could arise through quantum corrections, its implications for tests of Lorentz violations via the Cohen-Glashow proposal should be taken into account. The Lorentz-violating point-particle action invariant under DISIM{sub b}(2) is of Finsler type, for which the line element is homogeneous of degree 1 in displacements, but anisotropic. We derive DISIM{sub b}(2)-invariant wave equations for particles of spins 0, (1/2), and 1. The experimental bound, |b|<10{sup -26}, raises the question 'Why is the dimensionless constant b so small in very special relativity?'.

  19. Towards absorbing outer boundaries in general relativity

    NASA Astrophysics Data System (ADS)

    Buchman, Luisa T.; Sarbach, Olivier C. A.

    2006-12-01

    We construct exact solutions to the Bianchi equations on a flat spacetime background. When the constraints are satisfied, these solutions represent in- and outgoing linearized gravitational radiation. We then consider the Bianchi equations on a subset of flat spacetime of the form [0, T] × BR, where BR is a ball of radius R, and analyse different kinds of boundary conditions on ∂BR. Our main results are as follows. (i) We give an explicit analytic example showing that boundary conditions obtained from freezing the incoming characteristic fields to their initial values are not compatible with the constraints. (ii) With the help of the exact solutions constructed, we determine the amount of artificial reflection of gravitational radiation from constraint-preserving boundary conditions which freeze the Weyl scalar Ψ0 to its initial value. For monochromatic radiation with wave number k and arbitrary angular momentum number ell >= 2, the amount of reflection decays as (kR)-4 for large kR. (iii) For each L >= 2, we construct new local constraint-preserving boundary conditions which perfectly absorb linearized radiation with ell <= L. (iv) We generalize our analysis to a weakly curved background of mass M and compute first-order corrections in M/R to the reflection coefficients for quadrupolar odd-parity radiation. For our new boundary condition with L = 2, the reflection coefficient is smaller than that for the freezing Ψ0 boundary condition by a factor of M/R for kR > 1.04. Implications of these results for numerical simulations of binary black holes on finite domains are discussed.

  20. Multiple Biomarkers and Atrial Fibrillation in the General Population

    PubMed Central

    Schnabel, Renate B.; Wild, Philipp S.; Wilde, Sandra; Ojeda, Francisco M.; Schulz, Andreas; Zeller, Tanja; Sinning, Christoph R.; Kunde, Jan; Lackner, Karl J.

    2014-01-01

    Background Different biological pathways have been related to atrial fibrillation (AF). Novel biomarkers capturing inflammation, oxidative stress, and neurohumoral activation have not been investigated comprehensively in AF. Methods and Results In the population-based Gutenberg Health Study (n = 5000), mean age 56±11 years, 51% males, we measured ten biomarkers representing inflammation (C-reactive protein, fibrinogen), cardiac and vascular function (midregional pro adrenomedullin [MR-proADM], midregional pro atrial natriuretic peptide [MR-proANP], N-terminal pro-B-type natriuretic peptide [Nt-proBNP], sensitive troponin I ultra [TnI ultra], copeptin, and C-terminal pro endothelin-1), and oxidative stress (glutathioneperoxidase-1, myeloperoxidase) in relation to manifest AF (n = 161 cases). Individuals with AF were older, mean age 64.9±8.3, and more often males, 71.4%. In Bonferroni-adjusted multivariable regression analyses strongest associations per standard deviation increase in biomarker concentrations were observed for the natriuretic peptides Nt-proBNP (odds ratio [OR] 2.89, 99.5% confidence interval [CI] 2.14–3.90; P<0.0001), MR-proANP (OR 2.45, 99.5% CI 1.91–3.14; P<0.0001), the vascular function marker MR-proADM (OR 1.54, 99.5% CI 1.20–1.99; P<0.0001), TnI ultra (OR 1.50, 99.5% CI 1.19–1.90; P<0.0001) and. fibrinogen (OR 1.44, 99.5% CI 1.19–1.75; P<0.0001). Based on a model comprising known clinical risk factors for AF, all biomarkers combined resulted in a net reclassification improvement of 0.665 (99.3% CI 0.441–0.888) and an integrated discrimination improvement of >13%. Conclusions In conclusion, in our large, population-based study, we identified novel biomarkers reflecting vascular function, MR-proADM, inflammation, and myocardial damage, TnI ultra, as related to AF; the strong association of natriuretic peptides was confirmed. Prospective studies need to examine whether risk prediction of AF can be enhanced beyond clinical risk

  1. Limits of Generalizing in Education Research: Why Criteria for Research Generalization Should Include Population Heterogeneity and Uses of Knowledge Claims

    ERIC Educational Resources Information Center

    Ercikan, Kadriye; Roth, Wolff-Michael

    2014-01-01

    Context: Generalization is a critical concept in all research designed to generate knowledge that applies to all elements of a unit (population) while studying only a subset of these elements (sample). Commonly applied criteria for generalizing focus on experimental design or representativeness of samples of the population of units. The criteria…

  2. Asthma, airflow limitation, and mortality risk in the general population

    PubMed Central

    Huang, Shuang; Vasquez, Monica M; Halonen, Marilyn; Martinez, Fernando D; Guerra, Stefano

    2015-01-01

    Asthma and chronic obstructive pulmonary disease co-exist in a significant proportion of patients. Whether asthma increases mortality risk among subjects with airflow limitation remains controversial. We used data from 2121 adult participants in the population-based TESAOD cohort. At enrollment (1972–73), participants completed questionnaires and lung function tests. Participants were categorized into four groups based on the combination of airflow limitation (AL: FEV1/FVC<70%) and physician-confirmed asthma at baseline. Vital status as of January 2011 was assessed through the National Death Index. Cox proportional hazards models were used to test differences in mortality risk across the four AL/Asthma groups. In multivariate Cox models, the AL+/Asthma+ group had a 114% increased mortality risk over the follow-up as compared with the AL-/Asthma- group (adjHR: 2.14, 1.64–2.79). The corresponding Hazard Ratios were 1.09 (0.89–1.34) and 1.34 (1.14–1.57) for the AL-/Asthma+ and AL+/Asthma- groups, respectively. Among subjects with AL, asthma was associated with increased mortality risk (1.58, 1.17–2.12). However, this increased risk was substantially reduced and no longer significant after further adjustment for baseline FEV1 levels. Similar results were obtained when AL was defined as FEV1/FVCpopulation-based cohort subjects with concomitant AL and asthma had an increased risk of dying, which was mainly related to their baseline lung function deficits. PMID:25323227

  3. Derived relations and generalized alteration of preferences.

    PubMed

    Valdivia-Salas, Sonsoles; Dougher, Michael J; Luciano, Carmen

    2013-06-01

    The present study examined the role of derived relations in the generalizability of the evaluative conditioning effect. Healthy university students participated. Four geometrical shapes were first established as discriminative stimuli for the contingent presentation of pictograms (B1, B2, C1, and C2, respectively). We then assessed the reinforcing properties of B1 versus B2, and C1 versus C2 by using simultaneous discrimination tasks: at baseline (baseline assessment), after pairing B1 with aversive slides plus noise and B2 with pleasant slides (test I), and after employing equivalence training and testing to establish B1 as equivalent to C1 and B2 as equivalent to C2 (test II). Most participants (82%) in the experimental condition, as compared with the control conditions (17% and 10%), selected the discriminative shapes for B2 (test I) and C2 (test II) on most trials, replicating and extending previous findings. Subsequently, the geometrical shapes were established as equivalent to the letters X, Y, W, and Z, respectively, which then served as antecedent stimuli in simultaneous discrimination tasks as before (test III). As was expected, only participants in the experimental condition showed preference for the novel letters that were established as equivalent to B2-producing and C2-producing shapes. These findings suggest that the evaluative conditioning effect may extend far beyond the stimulus being de/valuated and narrow the behavioral repertoire. PMID:23242738

  4. BOOK REVIEW: Advanced Mechanics and General Relativity Advanced Mechanics and General Relativity

    NASA Astrophysics Data System (ADS)

    Louko, Jorma

    2011-04-01

    Joel Franklin's textbook `Advanced Mechanics and General Relativity' comprises two partially overlapping, partially complementary introductory paths into general relativity at advanced undergraduate level. Path I starts with the Lagrangian and Hamiltonian formulations of Newtonian point particle motion, emphasising the action principle and the connection between symmetries and conservation laws. The concepts are then adapted to point particle motion in Minkowski space, introducing Lorentz transformations as symmetries of the action. There follows a focused development of tensor calculus, parallel transport and curvature, using examples from Newtonian mechanics and special relativity, culminating in the field equations of general relativity. The Schwarzschild solution is analysed, including a detailed discussion of the tidal forces on a radially infalling observer. Basics of gravitational radiation are examined, highlighting the similarities to and differences from electromagnetic radiation. The final topics in Path I are equatorial geodesics in Kerr and the motion of a relativistic string in Minkowski space. Path II starts by introducing scalar field theory on Minkowski space as a limit of point masses connected by springs, emphasising the action principle, conservation laws and the energy-momentum tensor. The action principle for electromagnetism is introduced, and the coupling of electromagnetism to a complex scalar field is developed in a detailed and pedagogical fashion. A free symmetric second-rank tensor field on Minkowski space is introduced, and the action principle of general relativity is recovered from coupling the second-rank tensor to its own energy-momentum tensor. Path II then merges with Path I and, supplanted with judicious early selections from Path I, can proceed to the Schwarzschild solution. The choice of material in each path is logical and focused. A notable example in Path I is that Lorentz transformations in Minkowki space are introduced

  5. Comparison of Population Pyramid and Demographic Characteristics between People with an Intellectual Disability and the General Population

    ERIC Educational Resources Information Center

    Yen, Chia-Feng; Lin, Jin-Ding; Chiu, Tzu-Ying

    2013-01-01

    The purposes of this study were to measure disparities of age structure between people with an intellectual disability and general population, and to explore the difference of demographic characteristics between these two populations by using data from a population based register in Taiwan. Data were analyzed by SPSS 20.0 statistical software.…

  6. Directions in General Relativity, Vol. 1

    NASA Astrophysics Data System (ADS)

    Hu, B. L.; Ryan, M. P., Jr.; Vishveshwara, C. V.

    2005-10-01

    1. Remarks concerning the geometrics of gravity, gauge fields and quantum theory J. S. Anandan; 2. Gravity and the unification of fundamental interactions R. L. Arnowitt and P. Nath; 3. Minisuperspaces: symmetrics and quantization A. Ashtekar, R. S. Tate and C. Uggla; 4. Quantum cosmology B. K. Berger; 5. A pictorial history of some gravitational instanton D. Brill and K.- T. Pirk; 6. No time machines from lightlike sources in 2+1 gravity S. Deser and A. R. Steif; 7. Inhomogeneity and anisotropy genertation in FRW cosmologies G. F. R. Ellis and D. R. Matravers; 8. Misner, kinks and Black Holes D. Finkelstein; 9. The quantum mechanics of closed systems J. B. Hartle; 10. Cosmological vacuum open system W. A. Hiscock and D. A. Samuel; 11. Minisuperspace as a quantum open system B. L. Hu, J. P. Paz and S. Sinha; 12. Ricci flow on minisuperspaces and the geometry-topology problem J. Isenberg and M. Jackson; 13. Classical and quantum dynamics of Black Hole interiors W. Israel; 14. Matter time in canonical quantum gravity K. V. Kuchar; 15. The isotropy and homogeneity of the universe R. A. Matzner; 16. Recent advances in ADM reduction V. Moncrief; 17. Some progress in classical canonical gravity J. M. Nester; 18. Harmonic map formulation of colliding electrovac place waves Y. Nutku; 19. Geometry, the renormalization groups and gravity D. J. O'Connor and C. R. Stephens; 20. An example of the indeterminacy of the already-unified theory R. Penrose; 21. Nonstatic metric of Hiscock-Gott type A. K. Raychaudhuri; 22. Non-standard phase space variables, quantization and path-integrals, or little ado about much M. P. Ryan, Jr. and Sergio Hojmann; 23. The present status of the decaying neutrino theory D. W. Sciama; 24. Exploiting the computer to investigate Black Holes and cosmic censorship S. L. Shapiro and S. A. Teukolsky; 25. Misner space as a prototype for almost any pathology K. S. Thorne; 26. Relativity and rotation C. V. Vishveshwara; 27. The first law of Black Hole

  7. Schizotypy and specificity of negative emotions on an emotional Stroop paradigm in the general population.

    PubMed

    Yaffe, Beril; Walder, Deborah J

    2016-05-30

    Attentional-interference using emotional Stroop tasks (ESTs) is greater among individuals in the general population with positive (versus negative) schizotypal traits; specifically in response to negatively (versus positively) valenced words, potentially capturing threat-sensitivity. Variability in attentional-interference as a function of subcategories of negatively valenced words (and in relation to schizotypal traits) remains underexplored in EST studies. We examined attentional-interference across negative word subcategories (fear/anger/sadness/disgust), and in relation to positive schizotypy, among non-clinical individuals in the general population reporting varying degrees of schizotypal traits. As hypothesized, performance differed across word subcategories, though the pattern varied from expectation. Attentional-interference was greater for fear and sadness compared to anger; and analogous for fear, disgust, and sadness. In the high schizotypy group, positive schizotypal traits were directly associated with attentional-interference to disgust. Attentional-interference was comparable between high- and low-positive schizotypy. Results suggest negative emotion subcategories may differentially reflect threat-sensitivity. Disgust-sensitivity may be particularly salient in (non-clinical) positive schizotypy. Findings have implications for understanding negative emotion specificity and variability in stimulus presentation modality when studying threat-related attentional-interference. Finally, disgust-related attentional-interference may serve as a cognitive correlate of (non-clinical) positive schizotypy. Expanding this research to prodromal populations will help explore disgust-related attentional-interference as a potential cognitive marker of positive symptoms. PMID:27046393

  8. Prevalence and Factors Associated with Social Avoidance of Recovered SARS Patients in the Hong Kong General Population

    ERIC Educational Resources Information Center

    Lau, Joseph T. F.; Yang, Xilin; Wong, Eric; Tsui, H. Y.

    2006-01-01

    The study investigated the general population's perceived infectivity of asymptomatic and recovered severe acute respiratory syndrome (SARS) patients and factors associated with avoidance and discriminatory attitudes, including demographic background, SARS-related perceptions and emotional response to the SARS epidemic. A population-based survey…

  9. Vitamin D status and hypercholesterolemia in Spanish general population.

    PubMed

    Cutillas-Marco, Eugenia; Prosper, Amparo Fuertes; Grant, William B; Morales-Suárez-Varela, María M

    2013-06-01

    Low serum 25-hydroxyvitamin D [25(OH)D] levels have been associated with increased prevalence of cardiovascular diseases. A possible relation between lipids and 25(OH)D might explain this association. This investigation aimed to determine the association between vitamin D and cholesterol, as well as the influence of statins on this association. This was a cross-sectional population-based study with 177 subjects aged 18-84 years. We collected demographics and data on sun exposure, sun protection habits, current medication including lipid-lowering drugs, and estimated vitamin D intake. Serum measurements included levels of 25(OH)D, parathyroid hormone (PTH), calcium, phosphorus, total cholesterol, high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol, triglycerides, and fasting glucose. The mean 25(OH)D level was 24 ± 9 ng/ml. Young age (P = 0.04) and spending more than 1 h outdoors (P = 0.04) were independently associated with higher 25(OH)D levels. The 25(OH)D concentrations correlated negatively with total cholesterol (P = 0.01) and LDL cholesterol (P = 0.04) levels. The adjusted OR for total cholesterol > 200 mg/ml was 2.8 (range, 1.1-7.5). Receiving statins was associated with higher 25(OH)D levels (P = 0.04). In conclusion, this study supports an association between 25(OH)D levels and cholesterol. Further studies are required to explain this association. PMID:24516690

  10. Season of birth and population schizotypy: Results from a large sample of the adult general population.

    PubMed

    Konrath, Lisa; Beckius, Danièle; Tran, Ulrich S

    2016-08-30

    Although the last years have seen an increasing interest in schizotypy and its pathogenesis, there exist only a handful of studies examining the possible interaction between season of birth (SOB) and schizotypic personality structure. Available research used differing screening instruments, rendering comparisons between studies difficult, and sample sizes in adult populations may have been too small to detect a mild effect. The current study examined the association between SOB and psychometric schizotypy in the so far single-largest sample from the adult general population (N=8114), balanced for men and women, and utilizing a valid and reliable instrument for the assessment of schizotypy. Using the 12 most informative items of the Schizotypal Personality Questionnaire Brief, we obtained evidence of a small, but significant, effect of late winter and early spring births (February/March) on psychometric schizotypy. The effect was not constrained to women, but affected men and women alike. The observed association between SOB and schizotypy appears compatible with seasonal variations of temperature and influenza prevalence, and with recent evidence on seasonal variability in the activity of the human immune system. Our findings lend support to the continuum hypothesis of schizotypy and schizophrenia, for which SOB effects have been previously established. PMID:27310922

  11. Interpolating a consumption variable for scaling and generalizing potential population pressure on urbanizing natural areas

    USGS Publications Warehouse

    Varanka, Dalia

    2010-01-01

    Measures of population pressure, referring in general to the stress upon the environment by human consumption of resources, are imperative for environmental sustainability studies and management. Development based on resource consumption is the predominant factor of population pressure. This paper presents a spatial model of population pressure by linking consumption associated with regional urbanism and ecosystem services. Maps representing relative geographic degree and extent of natural resource consumption and degree and extent of impacts on surrounding areas are new, and this research represents the theoretical research toward this goal. With development, such maps offer a visualization tool for planners of various services, amenities for people, and conservation planning for ecologist. Urbanization is commonly generalized by census numbers or impervious surface area. The potential geographical extent of urbanism encompasses the environmental resources of the surrounding region that sustain cities. This extent is interpolated using kriging of a variable based on population wealth data from the U.S. Census Bureau. When overlayed with land-use/land-cover data, the results indicate that the greatest estimates of population pressure fall within mixed forest areas. Mixed forest areas result from the spread of cedar woods in previously disturbed areas where further disturbance is then suppressed. Low density areas, such as suburbanization and abandoned farmland are characteristic of mixed forest areas.

  12. Genetic Risk for Attention-Deficit/Hyperactivity Disorder Contributes to Neurodevelopmental Traits in the General Population

    PubMed Central

    Martin, Joanna; Hamshere, Marian L.; Stergiakouli, Evangelia; O’Donovan, Michael C.; Thapar, Anita

    2014-01-01

    Background Attention-deficit/hyperactivity disorder (ADHD) can be viewed as the extreme end of traits in the general population. Epidemiological and twin studies suggest that ADHD frequently co-occurs with and shares genetic susceptibility with autism spectrum disorder (ASD) and ASD-related traits. The aims of this study were to determine whether a composite of common molecular genetic variants, previously found to be associated with clinically diagnosed ADHD, predicts ADHD and ASD-related traits in the general population. Methods Polygenic risk scores were calculated in the Avon Longitudinal Study of Parents and Children (ALSPAC) population sample (N = 8229) based on a discovery case-control genome-wide association study of childhood ADHD. Regression analyses were used to assess whether polygenic scores predicted ADHD traits and ASD-related measures (pragmatic language abilities and social cognition) in the ALSPAC sample. Polygenic scores were also compared in boys and girls endorsing any (rating ≥1) ADHD item (n = 3623). Results Polygenic risk for ADHD showed a positive association with ADHD traits (hyperactive-impulsive, p = .0039; inattentive, p = .037). Polygenic risk for ADHD was also negatively associated with pragmatic language abilities (p = .037) but not with social cognition (p = .43). In children with a rating ≥1 for ADHD traits, girls had a higher polygenic score than boys (p = .003). Conclusions These findings provide molecular genetic evidence that risk alleles for the categorical disorder of ADHD influence hyperactive-impulsive and attentional traits in the general population. The results further suggest that common genetic variation that contributes to ADHD diagnosis may also influence ASD-related traits, which at their extreme are a characteristic feature of ASD. PMID:24673882

  13. Do Veterans Health Administration Enrollees Generalize to Other Populations?

    PubMed

    Wong, Edwin S; Wang, Virginia; Liu, Chuan-Fen; Hebert, Paul L; Maciejewski, Matthew L

    2016-08-01

    The Veterans Health Administration (VHA) has historically served a disproportionately male patient population with lower income and greater rates of mental illness than non-VHA populations. The generalizability of research based on VHA enrollees is unknown because the overlap between VHA and non-VHA populations has never been empirically examined. This study used 2013 National Health Interview Survey data to examine the extent to which VHA enrollees had similar demographic and health characteristics as individuals with Medicaid, Medicare, or private insurance coverage, based on propensity score models. A majority of male VHA enrollees were similar to Medicare beneficiaries suggesting greater generalizability of VHA studies than commonly hypothesized. Overlap declined when comparing with Medicaid enrollees or privately insured individuals, suggesting more limited generalizability of VHA studies to these populations. PMID:26589675

  14. [The HLA system in the Moroccan population: General review].

    PubMed

    Brick, C; Atouf, O; Essakalli, M

    2015-01-01

    The Moroccan population is an interesting study model of Human Leukocyte Antigen (HLA) polymorphism given its ethnic and genetic diversity. Through an analysis of the literature, this work proposes to establish a balance of knowledge for this population in the field of histocompatibility: HLA diversity, anthropology, transplantation and HLA associations and diseases. This analysis shows that the HLA system has not been fully explored within the Moroccan population. However, the results obtained allowed us to initiate a database reflecting the specific healthy Moroccan population HLA polymorphism to identify immigration flows and relationships with different people of the world and to reveal the association of certain HLA alleles with frequent pathologies. We also propose to analyze the reasons hindering the development of this activity in Morocco and we will try to identify some perspectives. PMID:26597780

  15. BOOK REVIEW: Equations of Motion in General Relativity Equations of Motion in General Relativity

    NASA Astrophysics Data System (ADS)

    Schäfer, Gerhard

    2012-03-01

    Devoted exclusively to the problem of motion in general relativity, this book by H. Asada, T. Futamase, and P. A. Hogan is highly welcome to close up a gap in the book sector presenting a concise account of theoretical developments and results on gravitational equations of motion achieved since the discovery of the binary neutron star system PSR 1913+16 in 1974. For the most part, the book is concerned with the development and application of the important post-Newtonian approximation (PNA) framework which allows for highly efficient approximate analytic solutions of the Einstein field equations for many-body systems in terms of a slow-motion and weak-field ordering parameter. That approximation scheme is shown to be applicable also to the external motion of strongly self-gravitating objects if their internal dynamics is frozen in (strong field point particle limit) and the external conditions fit. Relying on the expertise of the authors, the PNA framework is presented in a form which, at the 1PNA level, had become famous through the work by Einstein, Infeld and Hoffmann in 1938; therein, surface integrals over gravitational field expressions in the outside-body regime play a crucial role. Other approaches which also succeeded with the highest achieved PNA level so far are mentioned too, if not fully exhaustively with respect to the highest, the 3.5PNA level which contains the inverse power of the speed of light to the seventh order. Regarding the 3PNA, the reader gains a clear understanding of how the equations of motion for binary systems with compact components come about. Remarkably, no deviation from four-dimensional space-time is needed. Various explicit analytic expressions are derived for binary systems: the periastron advance and the orbital period at the 2PNA, the orbital decay through gravitational radiation reaction at the 2.5PNA, and effects of the gravitational spin-orbit and spin-spin couplings on the orbital motion. Also the propagation of light

  16. Knowledge of sexually transmissible infections: a comparison of prisoners and the general population.

    PubMed

    Malacova, E; Butler, T; Richters, J; Yap, L; Grant, L; Richards, A; Smith, A M A; Donovan, B

    2011-07-01

    The World Health Organization (WHO) has identified a failure to provide education for vulnerable populations such as prisoners as a contributing factor to the epidemic of sexually transmissible infections (STIs). Despite this recognition, little is known about prisoners' level of knowledge of STIs compared with the general population. Using computer-assisted telephone interviews, we compared a representative sample of 2289 Australian prisoners, aged 18-59 years from New South Wales and Queensland prisons with a representative community sample of 3536 participants from these two states. Prisoners had significantly better knowledge than the general community of chlamydia-related questions, while knowledge of herpes (genital and oral) was slightly better in the community sample. Prisoners who were aged over 25 years, not married, female, self-identified as either homosexual or bisexual and reported a history of STIs tended to have better STI knowledge levels. Despite their more disadvantaged backgrounds, prisoners demonstrated relatively good health literacy in relation to STIs. Ongoing education about the transmission risks of STIs for prisoners and the general community is needed. PMID:21729956

  17. Ischemic heart disease among the general Mongolian population: a review of epidemiological studies.

    PubMed

    Enkh-Oyun, Tsogzolbaatar; Kotani, Kazuhiko; Swanson, Eric

    2016-01-01

    Ischemic heart disease (IHD) is considered to be a pivotal health problem in Mongolia. To summarize the existing epidemiology of IHD in the general Mongolian population is crucial for primary prevention. The present review summarized population-based epidemiological data of IHD in Mongolia. When epidemiological studies were extracted from databases, very limited studies were available. The frequencies of IHD and IHD-attributable death rates appeared to be high and have an increased tendency in Mongolia. This could to be due to a gradually worsening state of potential IHD-related risk factors, such as smoking, hypertension, hypercholesterolemia, obesity and diabetes mellitus. This might indicate an urgent need of strategies for IHD and related risk factors. Anti-IHD strategies, such as more epidemiological studies and campaigns to increase awareness of IHD, at nationwide public health levels would be required in Mongolia for more effective prevention. PMID:26647395

  18. Stochastic resonance in a generalized Von Foerster population growth model

    SciTech Connect

    Lumi, N.; Mankin, R.

    2014-11-12

    The stochastic dynamics of a population growth model, similar to the Von Foerster model for human population, is studied. The influence of fluctuating environment on the carrying capacity is modeled as a multiplicative dichotomous noise. It is established that an interplay between nonlinearity and environmental fluctuations can cause single unidirectional discontinuous transitions of the mean population size versus the noise amplitude, i.e., an increase of noise amplitude can induce a jump from a state with a moderate number of individuals to that with a very large number, while by decreasing the noise amplitude an opposite transition cannot be effected. An analytical expression of the mean escape time for such transitions is found. Particularly, it is shown that the mean transition time exhibits a strong minimum at intermediate values of noise correlation time, i.e., the phenomenon of stochastic resonance occurs. Applications of the results in ecology are also discussed.

  19. Stochastic resonance in a generalized Von Foerster population growth model

    NASA Astrophysics Data System (ADS)

    Lumi, N.; Mankin, R.

    2014-11-01

    The stochastic dynamics of a population growth model, similar to the Von Foerster model for human population, is studied. The influence of fluctuating environment on the carrying capacity is modeled as a multiplicative dichotomous noise. It is established that an interplay between nonlinearity and environmental fluctuations can cause single unidirectional discontinuous transitions of the mean population size versus the noise amplitude, i.e., an increase of noise amplitude can induce a jump from a state with a moderate number of individuals to that with a very large number, while by decreasing the noise amplitude an opposite transition cannot be effected. An analytical expression of the mean escape time for such transitions is found. Particularly, it is shown that the mean transition time exhibits a strong minimum at intermediate values of noise correlation time, i.e., the phenomenon of stochastic resonance occurs. Applications of the results in ecology are also discussed.

  20. Modelo de Alfabetizacion: A Poblacion Urbana y Rural. Documento General (Literacy Model: Urban and Rural Populations. General Document).

    ERIC Educational Resources Information Center

    Instituto Nacional para la Educacion de los Adultos, Mexico City (Mexico).

    This document describes literacy models for urban and rural populations in Mexico. It contains four sections. The first two sections (generalizations about the population and considerations about the teaching of adults) discuss the environment that creates illiterate adults and also describe some of the conditions under which learning takes place…

  1. A dangerous cocktail: Alcohol consumption increases suicidal ideations among problem gamblers in the general population.

    PubMed

    Kim, Hyoun S; Salmon, Melissa; Wohl, Michael J A; Young, Matthew

    2016-04-01

    The current research examined whether alcohol consumption exacerbates suicidal ideations among gamblers in the general population. While prior research suggests problem gambling severity and excessive alcohol consumption are unique predictors of suicidal behaviors, the extant literature as almost exclusively focused on gamblers in treatment. This represents a significant gap in the literature as less than 10% of gamblers seek treatment. Furthermore, gamblers in treatment are not representative of gamblers in the general population, precluding a simple generalization of research findings. We address this gap using data obtained from the Canadian Community Health Survey (Cycle 4.1)--a cross-sectional national survey that assesses health-related information among the Canadian population. To this end, we conducted a moderation analysis with problem gambling severity as the independent variable, weekly alcohol consumption as the moderator variable and suicidal ideations (in the past 12 months) as the dependent variable. The results found that alcohol consumption alone did not reliably predict suicidal ideation among gamblers who did not gamble problematically. However, as predicted, the odds of suicidal ideation were greatest among problem gamblers who frequently consumed alcohol. Thus, it may behoove policy makers to re-visit the availability of alcohol in gambling venues. Moreover, responsible gambling-oriented education initiatives may be advanced by informing gamblers about the increased risk of suicidal ideations when problematic gambling is combined with frequent alcohol consumption. PMID:26790140

  2. Long-term survival following intensive care: subgroup analysis and comparison with the general population.

    PubMed

    Wright, J C; Plenderleith, L; Ridley, S A

    2003-07-01

    This study aimed to compare the very long-term survival of critically ill patients with that of the general population, and examine the association among age, sex, admission diagnosis, APACHE II score and mortality. In a retrospective observational cohort study of prospectively gathered data, 2104 adult patients admitted to the intensive care unit (ICU) of a teaching hospital in Glasgow from 1985 to 1992, were followed until 1997. Vital status at five years was compared with that of an age- and sex-matched Scottish population. Five-year mortality for the ICU patients was 47.1%, 3.4 times higher than that of the general population. For those surviving intensive care the five-year mortality was 33.4%. Mortality was greater than that of the general population for four years following intensive care unit admission (95% confidence interval included 1.0 at four years). Multivariate analysis showed that risk factors for mortality in those admitted to ICU were age, APACHE II score on admission and diagnostic category. Mortality was higher for those admitted with haematological (87.5%) and neurological diseases (61.7%) and septic shock (62.9%). A risk score was produced: Risk Score = 10 (age hazard ratio + APACHE II hazard ratio + diagnosis hazard ratio). None of the patients with a risk score > 100 survived more than five years and for those who survived to five years the mean risk score was 57. Long-term survival following intensive care is not only related to age and severity of illness but also diagnostic category. The risk of mortality in survivors of critical illness matches that of the normal population after four years. Age, severity of illness and diagnosis can be combined to provide an estimate of five-year survival. PMID:12790812

  3. Environmental Pollution Control: Two Views from the General Population

    ERIC Educational Resources Information Center

    Althoff, Phillip; Greig, William H.

    1977-01-01

    Citizens exhibitied concern about pollution, a low level of trust in governmental and industrial efforts, and a low level of dedication to environmental protection. Demands to clean up the environment came from one segment of the population while demands to solve the energy crisis came from other segments. (AJ)

  4. Assessing Methods for Generalizing Experimental Impact Estimates to Target Populations

    ERIC Educational Resources Information Center

    Kern, Holger L.; Stuart, Elizabeth A.; Hill, Jennifer; Green, Donald P.

    2016-01-01

    Randomized experiments are considered the gold standard for causal inference because they can provide unbiased estimates of treatment effects for the experimental participants. However, researchers and policymakers are often interested in using a specific experiment to inform decisions about other target populations. In education research,…

  5. Emergent General Relativity and Local Translation Symmetry in Tensor Model

    NASA Astrophysics Data System (ADS)

    Sasakura, Naoki

    2009-12-01

    The tensor model is discussed as theory of dynamical fuzzy spaces and as a way to formulate gravity on fuzzy spaces. From numerical analyses, it is shown that the low-lying long-wavelength fluctuation spectra around Gaussian background solutions in the tensor model are in agreement with the geometric fluctuations on flat spaces in the general relativity. It is also shown that part of the orthogonal symmetry of the tensor model spontaneously broken by the backgrounds correspond to the local translation symmetry of the general relativity. Thus the tensor model can provide an interesting model of simultaneous emergence of space and the general relativity including the local translation symmetry.

  6. General Relativity Theory - Well Proven and Also Incomplete: Further Arguments

    NASA Astrophysics Data System (ADS)

    Brandes, Jürgen

    In the former article "General Relativity Theory - well proven and also incomplete?" with a few arguments it was proven that general relativity (GRT) makes contradictory predictions about the total energy of a particle resting in the gravitational field. With a few further arguments it was proven that this contradiction is resolved by expanding general relativity. General relativity is contradictious in energy questions since on one side the total energy of a particle resting in the gravitational field is lower than its rest mass (there is energy needed to pull out the particle from the gravitational field) while on the other side it is equal to its rest mass (this is a consequence of the equivalence principle). In the following article these considerations are generalized to a moving particle. A particle moving in the gravitational field has a total energy less than its rest mass times the relativistic γ-factor since there is energy needed to pull the particle out without changing its velocity. On the other side total energy of a moving particle is equal to its rest mass times the relativistic γ-factor (this is a consequence of the equivalence principle, too). This contradiction is resolved by expanding general relativity in the same manner as above. The other fact: Though it is not the aim of the author to reject general relativity but to expand it, he is treated as some uncritical anti-relativist - since the start of his considerations and meanwhile for more than 20 years.

  7. ECOLOGICAL THEORY. A general consumer-resource population model.

    PubMed

    Lafferty, Kevin D; DeLeo, Giulio; Briggs, Cheryl J; Dobson, Andrew P; Gross, Thilo; Kuris, Armand M

    2015-08-21

    Food-web dynamics arise from predator-prey, parasite-host, and herbivore-plant interactions. Models for such interactions include up to three consumer activity states (questing, attacking, consuming) and up to four resource response states (susceptible, exposed, ingested, resistant). Articulating these states into a general model allows for dissecting, comparing, and deriving consumer-resource models. We specify this general model for 11 generic consumer strategies that group mathematically into predators, parasites, and micropredators and then derive conditions for consumer success, including a universal saturating functional response. We further show how to use this framework to create simple models with a common mathematical lineage and transparent assumptions. Underlying assumptions, missing elements, and composite parameters are revealed when classic consumer-resource models are derived from the general model. PMID:26293960

  8. Evaluating Preference Assessments for Use in the General Education Population

    ERIC Educational Resources Information Center

    Resetar, Jennifer L.; Noell, George H.

    2008-01-01

    This study compared the effectiveness of a multiple-stimulus-without-replacement (MSWO) preference assessment and teacher preference ranking in identifying reinforcers for use in a general education setting with typically developing elementary-school children. The mean number of digits correctly answered was greater in the MSWO-selected reward and…

  9. From massive gravity to modified general relativity II

    NASA Astrophysics Data System (ADS)

    Grigore, D. R.; Scharf, G.

    2011-05-01

    We continue our investigation of massive gravity in the massless limit of vanishing graviton mass. From gauge invariance we derive the most general coupling between scalar matter and gravity. We get further couplings beside the standard coupling to the energy-momentum tensor. On the classical level this leads to a further modification of general relativity.

  10. 2. GENERAL VIEW SHOWING RELATION OF BRIDGE TO THE TOPOGRAPHY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. GENERAL VIEW SHOWING RELATION OF BRIDGE TO THE TOPOGRAPHY OF THE APPROACH ROAD. - Speicher Bridge, Church Road over Tulpehocken Creek between Penn & North Heidelberg Townships, Bernville, Berks County, PA

  11. Galileons as the scalar analogue of general relativity

    NASA Astrophysics Data System (ADS)

    Klein, Remko; Ozkan, Mehmet; Roest, Diederik

    2016-02-01

    We establish a correspondence between general relativity with diffeomorphism invariance and scalar field theories with Galilean invariance: notions such as the Levi-Civita connection and the Riemann tensor have a Galilean counterpart. This suggests Galilean theories as the unique nontrivial alternative to gauge theories (including general relativity). Moreover, it is shown that the requirement of first-order Palatini formalism uniquely determines the Galileon models with second-order field equations, similar to the Lovelock gravity theories. Possible extensions are discussed.

  12. Generalized Uncertainty Relations in the Non-commutative Plane

    NASA Astrophysics Data System (ADS)

    Chung, Won Sang

    2015-09-01

    In this paper we study two-dimensional noncommutative quantum mechanics (NCQM) with the generalized uncertainty relations . We find the new NCQM algebra from the generalized uncertainty relations. We construct a operator commuting with and discuss two possibilities; One is the case that also commutes with and another is the case that does not commute with . For both case we consider a motion of a charged particle in a magnetic field with a harmonic oscillator potential in the noncommutative plane.

  13. Pressure to change drinking behavior: An exploratory analysis of US general population subgroups

    PubMed Central

    Polcin, Douglas L.; Greenfield, Thomas K.; Kerr, William C.; Bond, Jason

    2014-01-01

    Background General population studies have shown that pressure from others to change drinking can come from different sources. Receipt of informal pressure (IP) and formal pressure (FP) is known to vary by quantity and consequences of drinking, but less is known about how pressure varies among subgroups of the population. Method This exploratory study utilizes data from the National Alcohol Surveys from 1995–2010 (N=26,311) and examines associations between receipt of pressure and subgroups of drinkers. Results Increased relative risk of receiving IP and FP were observed for individuals reporting an arrest for driving after drinking and illicit drug use while poverty and lack of private health insurance increased risk of receipt of formal pressures. Regular marijuana use increased IP. Conclusion The subgroups that were studied received increased pressures to change drinking behavior, though disentangling the societal role of pressure and how it may assist with interventions, help seeking, and natural recovery is needed. PMID:25346550

  14. Helicobacter pylori Infection in the general population: A Middle Eastern perspective

    PubMed Central

    Khedmat, Hossein; Karbasi-Afshar, Reza; Agah, Shahram; Taheri, Saeed

    2013-01-01

    Helicobacter pylori (H.pylori) infection is probably the most important factor that has been associated with the development of gastric cancers in human populations. However, there are no reliable data on the prevalence of this infection in the Middle East. In this article, based on a comprehensive literature review, we aimed to evaluate the situation in this region. The literature has been searched for the incidence and prevalence of H.pylori infection by Pubmed and Google Scholar. Search was repeated for each of the Middle Eastern countries, and to empower the method, citations of each found article were searched for the related studies. Seventy seven reports from the countries of the Middle East region had been reviewed and they all indicated a high rate of infection either in the general population or in the dyspeptic patients, the rate seemed to be higher in patients with dyspepsia, in patients with histologically confirmed gastritis and in patients of older age groups. PMID:24294467

  15. The Relationship between General Population Suicide Rates and the Internet: A Cross-National Study

    ERIC Educational Resources Information Center

    Shah, Ajit

    2010-01-01

    Internet Web sites and chat rooms have been reported both to promote suicides and have a positive beneficial effect on suicidal individuals. There is a paucity of studies examining the role of the Internet in general population suicide rates. The relationship between general population suicide rates and the prevalence of Internet users was…

  16. Intimate Partner Violence among General and Urban Poor Populations in Kathmandu, Nepal

    ERIC Educational Resources Information Center

    Oshiro, Azusa; Poudyal, Amod K.; Poudel, Krishna C.; Jimba, Masamine; Hokama, Tomiko

    2011-01-01

    Comparative studies are lacking on intimate partner violence (IPV) between urban poor and general populations. The objective of this study is to identify the prevalence and risk factors of physical IPV among the general and poor populations in urban Nepal. A cross-sectional study was conducted by structured questionnaire interview. Participants…

  17. Suicidal Behaviors among Clients at an Outpatient Psychology Clinic versus the General Population.

    ERIC Educational Resources Information Center

    Linehan, Marsha M.; Laffaw, Julie A.

    1982-01-01

    Compared suicidal behaviors among two populations in the same geographical area: clients at a psychology clinic versus individuals from the general population. In both samples, 10 percent of the individuals reported prior parasuicidal behavior; the two populations were also quite similar on reports of prior suicidal ideation. (JAC)

  18. Correlates of Peripheral Blood Mitochondrial DNA Content in a General Population

    PubMed Central

    Knez, Judita; Winckelmans, Ellen; Plusquin, Michelle; Thijs, Lutgarde; Cauwenberghs, Nicholas; Gu, Yumei; Staessen, Jan A.; Nawrot, Tim S.; Kuznetsova, Tatiana

    2016-01-01

    Accumulation of mitochondrial DNA (mtDNA) mutations leads to alterations of mitochondrial biogenesis and function that might produce a decrease in mtDNA content within cells. This implies that mtDNA content might be a potential biomarker associated with oxidative stress and inflammation. However, data on correlates of mtDNA content in a general population are sparse. Our goal in the present study was to describe in a randomly recruited population sample the distribution and determinants of peripheral blood mtDNA content. From 2009 to 2013, we examined 689 persons (50.4% women; mean age = 54.4 years) randomly selected from a Flemish population (Flemish Study on Environment, Genes, and Health Outcomes). Relative mtDNA copy number as compared with nuclear DNA was measured by quantitative real-time polymerase chain reaction in peripheral blood. There was a curvilinear relationship between relative mtDNA copy number and age. mtDNA content slightly increased until the fifth decade of life and declined in older subjects (Page2 = 0.0002). mtDNA content was significantly higher in women (P = 0.007) and increased with platelet count (P < 0.0001), whereas it was inversely associated with white blood cell count (P < 0.0001). We also observed lower mtDNA content in women using estroprogestogens (P = 0.044). This study demonstrated in a general population that peripheral blood mtDNA content is significantly associated with sex and age. Blood mtDNA content is also influenced by platelet and white blood cell counts and estroprogestogen intake. Further studies are required to clarify the impact of chronic inflammation and hormone therapy on mitochondrial function. PMID:26702630

  19. Course and Prognostic Factors for Neck Pain in the General Population

    PubMed Central

    Hogg-Johnson, Sheilah; van der Velde, Gabrielle; Haldeman, Scott; Holm, Lena W.; Carragee, Eugene J.; Hurwitz, Eric L.; Côté, Pierre; Nordin, Margareta; Peloso, Paul M.; Guzman, Jaime; Cassidy, J. David

    2008-01-01

    Study Design Best evidence synthesis. Objective To undertake a best evidence synthesis on course and prognosis of neck pain and its associated disorders in the general population. Summary of Background Data Knowing the course of neck pain guides expectations for recovery. Identifying prognostic factors assists in planning public policies, formulating interventions, and promoting lifestyle changes to decrease the burden of neck pain. Methods The Bone and Joint Decade 2000 –2010 Task Force on Neck Pain and its Associated Disorders (Neck Pain Task Force) conducted a critical review of literature published between 1980 and 2006 to assemble the best evidence on neck pain. Findings fromstudiesmeeting criteria for scientific validity were abstracted into evidence tables and included in a best evidence synthesis. Results We found 226 articles on the course and prognostic factors in neck pain and its associated disorders. After critical review, 70 (31) of these were accepted on scientific merit. Six studies related to course and 7 to prognostic factors in the general population. Between half and three quarters of persons in these populations with current neck pain will report neck pain again 1 to 5 years later. Younger age predicted better outcome. General exercise was unassociated with outcome, although regular bicycling predicted poor outcome in 1 study. Psychosocial factors, including psychologic health, coping patterns, and need to socialize, were the strongest prognostic factors. Several potential prognostic factors have not been well studied, including degenerative changes, genetic factors, and compensation policies. Conclusion The Neck Pain Task Force undertook a best evidence synthesis to establish a baseline of the current best evidence on the course and prognosis for this symptom. General exercise was not prognostic of better outcome; however, several psychosocial factors were prognostic of outcome.

  20. Celebrity Suicides and Their Differential Influence on Suicides in the General Population: A National Population-Based Study in Korea

    PubMed Central

    Myung, Woojae; Won, Hong-Hee; Fava, Maurizio; Mischoulon, David; Yeung, Albert; Lee, Dongsoo; Kim, Doh Kwan

    2015-01-01

    Objective Although evidence suggests that there is an increase in suicide rates in the general population following celebrity suicide, the rates are heterogeneous across celebrities and countries. It is unclear which is the more vulnerable population according to the effect sizes of celebrity suicides to general population. Methods All suicide victims in the general population verified by the Korea National Statistical Office and suicides of celebrity in South Korea were included for 7 years from 2005 to 2011. Effect sizes were estimated by comparing rates of suicide in the population one month before and after each celebrity suicide. The associations between suicide victims and celebrities were examined. Results Among 94,845 suicide victims, 17,209 completed suicide within one month after 13 celebrity suicides. Multivariate logistic regression analyses revealed that suicide victims who died after celebrity suicide were significantly likely to be of age 20-39, female, and to die by hanging. These qualities were more strongly associated among those who followed celebrity suicide with intermediate and high effect sizes than lower. Younger suicide victims were significantly associated with higher effect size, female gender, white collar employment, unmarried status, higher education, death by hanging, and night-time death. Characteristics of celebrities were significantly associated with those of general population in hanging method and gender. Conclusion Individuals who commit suicide after a celebrity suicide are likely to be younger, female, and prefer hanging as method of suicide, which are more strongly associated in higher effect sizes of celebrity suicide. PMID:25866521

  1. Introduction to General Relativity and John Archibald Wheeler

    NASA Astrophysics Data System (ADS)

    Ciufolini, Ignazio; Matzner, Richard

    John Archibald Wheeler was born on July 9, 1911, in Jacksonville, Florida, and passed away on April 13, 2008, in Hightstown, New Jersey; his influence on gravitational physics and science in general will remain forever. Among his many and important contributions to physics, he was one of the fathers of the renaissance of General Relativity. After a golden starting age of General Relativity, a few years after the Einstein's papers of 1915-1916, Einstein's gravitational theory was for many years, to quote the preface of a 1960 book of General Relativity [1], confined to "an ivory tower…and no doubt many a relativist looks forward to the day when the governments will seek his opinion on important questions".

  2. On Clifford Space Relativity, Black Hole Entropy, Rainbow Metrics, Generalized Dispersion and Uncertainty Relations

    NASA Astrophysics Data System (ADS)

    Castro, Carlos

    2014-08-01

    An analysis of some of the applications of Clifford space relativity to the physics behind the modified black hole entropy-area relations, rainbow metrics, generalized dispersion and minimal length stringy uncertainty relations is presented.

  3. On Clifford Space Relativity, Black Hole Entropy, Rainbow Metrics, Generalized Dispersion and Uncertainty Relations

    NASA Astrophysics Data System (ADS)

    Castro, Carlos

    2014-09-01

    An analysis of some of the applications of Clifford space relativity to the physics behind the modified black hole entropy-area relations, rainbow metrics, generalized dispersion and minimal length stringy uncertainty relations is presented.

  4. [Population problems in the areas where the relatives of overseas Chinese reside].

    PubMed

    Lan, Y

    1983-11-29

    In the areas where relatives of overseas Chinese (huaqiao) reside, the population density is normally high. For example, in Jinjiang county of Fujian Province, where there is such population, the population density is six times that of Fujian Province in general. The main reason for this situation is that the local economy has improved greatly since 1949 and the living standard in the local area has been elevated as a result of improved medical care and a sharply reduced death rate. Financial resources sent back by the overseas Chinese to their relatives at home have also contributed to the local economic development. The traditional belief favoring more children to carry on the family line is still popular among the general public. All these factors have contributed to a rapid population growth, and the problem of over-population is becoming increasingly serious. At the present time, an understanding has to be reached that population control is in the best interest of both the local people and their relatives overseas. In addition to a control of the population growth, the quality of the population should also be improved. Some advantageous conditions in the areas inhabited by the relatives of overseas Chinese are helpful to reach the goal of family planning: (1) More advanced development in business and industry, (2) more schools established with financial support sent in from overseas, and (3) a general higher cultural and educational level of the local people. Because of these conditions, population control should be achieved more easily than in other places. PMID:12159377

  5. Generalized Uncertainty Relation in the Non-commutative Quantum Mechanics

    NASA Astrophysics Data System (ADS)

    Chung, Won Sang

    2016-06-01

    In this paper the non-commutative quantum mechanics (NCQM) with the generalized uncertainty relations {Δ } x1 {Δ } x2 ≥ {θ}/{2}, {Δ} p1 {Δ } p2 ≥ {bar{θ}}/{2}, {Δ } xi {Δ } pi ≥ {hbar _{eff}}/{2} is discussed. Four each uncertainty relation, wave functions saturating each uncertainty relation are explicitly constructed. The unitary operators relating the non-commutative position and momentum operators to the commutative position and momentum operators are also investigated. We also discuss the uncertainty relation related to the harmonic oscillator.

  6. Predicting acute maxillary sinusitis in a general practice population.

    PubMed Central

    Hansen, J. G.; Schmidt, H.; Rosborg, J.; Lund, E.

    1995-01-01

    OBJECTIVE--To evaluate the diagnostic value of symptoms, signs, erythrocyte sedimentation rate, and C reactive protein for acute maxillary sinusitis. DESIGN--Prospective cohort study. SETTING--Danish general practice in cooperation with the otorhinolaryngology and neuroradiology department at Aalborg County Hospital. SUBJECTS--174 patients aged 18-65 years who were suspected by the general practitioner of having acute maxillary sinusitis. MAIN OUTCOME MEASURE--The independent association of symptoms, signs, erythrocyte sedimentation rate, and concentration of C reactive protein in patients with acute maxillary sinusitis defined as purulent or mucopurulent antral aspirate. RESULTS--Only raised erythrocyte sedimentation rate (P = 0.01) and raised C reactive protein (P = 0.007) were found to be independently associated with a diagnosis of acute maxillary sinusitis. The combination of the two variables had a sensitivity of 0.82 and a specificity of 0.57. CONCLUSION--Erythrocyte sedimentation rate and C reactive protein are useful diagnostic criteria for acute maxillary sinusitis. PMID:7627042

  7. A General Population Genetic Framework for Antagonistic Selection That Accounts for Demography and Recurrent Mutation

    PubMed Central

    Connallon, Tim; Clark, Andrew G.

    2012-01-01

    Antagonistic selection—where alleles at a locus have opposing effects on male and female fitness (“sexual antagonism”) or between components of fitness (“antagonistic pleiotropy”)—might play an important role in maintaining population genetic variation and in driving phylogenetic and genomic patterns of sexual dimorphism and life-history evolution. While prior theory has thoroughly characterized the conditions necessary for antagonistic balancing selection to operate, we currently know little about the evolutionary interactions between antagonistic selection, recurrent mutation, and genetic drift, which should collectively shape empirical patterns of genetic variation. To fill this void, we developed and analyzed a series of population genetic models that simultaneously incorporate these processes. Our models identify two general properties of antagonistically selected loci. First, antagonistic selection inflates heterozygosity and fitness variance across a broad parameter range—a result that applies to alleles maintained by balancing selection and by recurrent mutation. Second, effective population size and genetic drift profoundly affect the statistical frequency distributions of antagonistically selected alleles. The “efficacy” of antagonistic selection (i.e., its tendency to dominate over genetic drift) is extremely weak relative to classical models, such as directional selection and overdominance. Alleles meeting traditional criteria for strong selection (Nes >> 1, where Ne is the effective population size, and s is a selection coefficient for a given sex or fitness component) may nevertheless evolve as if neutral. The effects of mutation and demography may generate population differences in overall levels of antagonistic fitness variation, as well as molecular population genetic signatures of balancing selection. PMID:22298707

  8. A general population genetic framework for antagonistic selection that accounts for demography and recurrent mutation.

    PubMed

    Connallon, Tim; Clark, Andrew G

    2012-04-01

    Antagonistic selection--where alleles at a locus have opposing effects on male and female fitness ("sexual antagonism") or between components of fitness ("antagonistic pleiotropy")--might play an important role in maintaining population genetic variation and in driving phylogenetic and genomic patterns of sexual dimorphism and life-history evolution. While prior theory has thoroughly characterized the conditions necessary for antagonistic balancing selection to operate, we currently know little about the evolutionary interactions between antagonistic selection, recurrent mutation, and genetic drift, which should collectively shape empirical patterns of genetic variation. To fill this void, we developed and analyzed a series of population genetic models that simultaneously incorporate these processes. Our models identify two general properties of antagonistically selected loci. First, antagonistic selection inflates heterozygosity and fitness variance across a broad parameter range--a result that applies to alleles maintained by balancing selection and by recurrent mutation. Second, effective population size and genetic drift profoundly affect the statistical frequency distributions of antagonistically selected alleles. The "efficacy" of antagonistic selection (i.e., its tendency to dominate over genetic drift) is extremely weak relative to classical models, such as directional selection and overdominance. Alleles meeting traditional criteria for strong selection (N(e)s > 1, where N(e) is the effective population size, and s is a selection coefficient for a given sex or fitness component) may nevertheless evolve as if neutral. The effects of mutation and demography may generate population differences in overall levels of antagonistic fitness variation, as well as molecular population genetic signatures of balancing selection. PMID:22298707

  9. The general class of the vacuum spherically symmetric equations of the general relativity theory

    SciTech Connect

    Karbanovski, V. V. Sorokin, O. M.; Nesterova, M. I.; Bolotnyaya, V. A.; Markov, V. N. Kairov, T. V.; Lyash, A. A.; Tarasyuk, O. R.

    2012-08-15

    The system of the spherical-symmetric vacuum equations of the General Relativity Theory is considered. The general solution to a problem representing two classes of line elements with arbitrary functions g{sub 00} and g{sub 22} is obtained. The properties of the found solutions are analyzed.

  10. Clarifying possible misconceptions in the foundations of general relativity

    NASA Astrophysics Data System (ADS)

    Brown, Harvey R.; Read, James

    2016-05-01

    We discuss what we take to be three possible misconceptions in the foundations of general relativity, relating to: (a) the interpretation of the weak equivalence principle and the relationship between gravity and inertia; (b) the connection between gravitational redshift results and spacetime curvature; and (c) the Einstein equivalence principle and the ability to "transform away" gravity in local inertial coordinate systems.

  11. [The female role as assessment of mental health of women within the general population of Cantabria].

    PubMed

    de Santiago Díaz, A; Vázquez Barquero, J L; Díez Manrique, J F

    1994-01-01

    This paper tries to analyse the relationship between traditional feminine role (marriage, motherhood and housing) and mental health in spanish women. The General Health Questionnaire 60-items (GHQ-60) was used to define "cases" in a random sample of the general population of Cantabria consisting of 630 women aged 17 and over. The rate of probable prevalence of psychiatric disorders was 26.4%. In contrast to previous studies, motherhood and traditional feminine role correlated with the lowest GHQ-60 mean scores. Occupational status was not related to mental health. Women living with husband, children, parents and/or parents-in-law scored lower on GHQ-60 than those living with husband and children. These results are discussed in the light of previous findings in the literature. At least, they reconfirm the importance of socio-cultural factors in community psychiatric disorder. PMID:7817849

  12. The Role of Self-Compassion in Buffering Symptoms of Depression in the General Population

    PubMed Central

    Körner, Annett; Coroiu, Adina; Copeland, Laura; Gomez-Garibello, Carlos; Albani, Cornelia; Zenger, Markus; Brähler, Elmar

    2015-01-01

    Self-compassion, typically operationalized as the total score of the Self-Compassion Scale (SCS; Neff, 2003b), has been shown to be related to increased psychological well-being and lower depression in students of the social sciences, users of psychology websites and psychotherapy patients. The current study builds on the existing literature by examining the link between self-compassion and depressive symptomatology in a sample representative of the German general population (n = 2,404). The SCS subscales of self-judgment, isolation, and over-identification, and the “self-coldness”, composite score, which encompass these three negative subscales, consistently differed between subsamples of individuals without any depressive symptoms, with any depressive syndromes, and with major depressive disorder. The contribution of the positive SCS subscales of self-kindness, common humanity, and mindfulness to the variance in depressive symptomatology was almost negligible. However, when combined to a “self-compassion composite”, the positive SCS subscales significantly moderated the relationship between “self-coldness” and depressive symptoms in the general population. This speaks for self-compassion having the potential to buffer self-coldness related to depression—providing an argument for interventions that foster self-caring, kind, and forgiving attitudes towards oneself. PMID:26430893

  13. Gender Differences in Depressive Symptom Profile: Results from Nationwide General Population Surveys in Korea

    PubMed Central

    Kim, Ji-Hyun; Cho, Maeng Je; Hong, Jin Pyo; Bae, Jae Nam; Cho, Seong-Jin; Hahm, Bong-Jin; Lee, Dong-Woo; Park, Jong-Ik; Lee, Jun-Young; Jeon, Hong Jin

    2015-01-01

    This study investigated gender differences in symptom profiles of major depressive disorder (MDD) in the Korean general population. Data were pooled from the series of nationwide Korean Epidemiologic Catchment Area surveys conducted in 2001, 2006 and 2011, respectively. Of the 18,807 participants, 507 (397 women and 110 men) were diagnosed with MDD within the prior 12 months. In agreement with previous studies, women with MDD appeared to be more vulnerable to experiencing atypical depressive episodes defined as depression with two or more symptoms of fatigue, increased appetite and hypersomnia (P < 0.001). In terms of individual symptoms, female gender was significantly related with higher prevalence of fatigue (P = 0.008), hypersomnia (P = 0.001), noticeable psychomotor retardation (P = 0.029) and suicidal attempts (P = 0.016) with adjustment for birth cohort effect, partner status, and employment status. In the same analysis, men with MDD appeared more vulnerable to decreased libido than women (P = 0.009). This is the first report to demonstrate gender differences in symptomatology of MDD in the general Korean population, and the results are comparable to previous investigations from western societies. Assumingly, the intercultural similarity in female preponderance to atypical depression might reflect the common biological construct underlying the gender difference in mechanism of MDD. In clinical settings, gender differences of MDD should be carefully considered, because these features could be related with treatment response and drug side effects. PMID:26539012

  14. Gender Differences in Depressive Symptom Profile: Results from Nationwide General Population Surveys in Korea.

    PubMed

    Kim, Ji-Hyun; Cho, Maeng Je; Hong, Jin Pyo; Bae, Jae Nam; Cho, Seong-Jin; Hahm, Bong-Jin; Lee, Dong-Woo; Park, Jong-Ik; Lee, Jun-Young; Jeon, Hong Jin; Chang, Sung Man

    2015-11-01

    This study investigated gender differences in symptom profiles of major depressive disorder (MDD) in the Korean general population. Data were pooled from the series of nationwide Korean Epidemiologic Catchment Area surveys conducted in 2001, 2006 and 2011, respectively. Of the 18,807 participants, 507 (397 women and 110 men) were diagnosed with MDD within the prior 12 months. In agreement with previous studies, women with MDD appeared to be more vulnerable to experiencing atypical depressive episodes defined as depression with two or more symptoms of fatigue, increased appetite and hypersomnia (P < 0.001). In terms of individual symptoms, female gender was significantly related with higher prevalence of fatigue (P = 0.008), hypersomnia (P = 0.001), noticeable psychomotor retardation (P = 0.029) and suicidal attempts (P = 0.016) with adjustment for birth cohort effect, partner status, and employment status. In the same analysis, men with MDD appeared more vulnerable to decreased libido than women (P = 0.009). This is the first report to demonstrate gender differences in symptomatology of MDD in the general Korean population, and the results are comparable to previous investigations from western societies. Assumingly, the intercultural similarity in female preponderance to atypical depression might reflect the common biological construct underlying the gender difference in mechanism of MDD. In clinical settings, gender differences of MDD should be carefully considered, because these features could be related with treatment response and drug side effects. PMID:26539012

  15. The Role of Self-Compassion in Buffering Symptoms of Depression in the General Population.

    PubMed

    Körner, Annett; Coroiu, Adina; Copeland, Laura; Gomez-Garibello, Carlos; Albani, Cornelia; Zenger, Markus; Brähler, Elmar

    2015-01-01

    Self-compassion, typically operationalized as the total score of the Self-Compassion Scale (SCS; Neff, 2003b), has been shown to be related to increased psychological well-being and lower depression in students of the social sciences, users of psychology websites and psychotherapy patients. The current study builds on the existing literature by examining the link between self-compassion and depressive symptomatology in a sample representative of the German general population (n = 2,404). The SCS subscales of self-judgment, isolation, and over-identification, and the "self-coldness", composite score, which encompass these three negative subscales, consistently differed between subsamples of individuals without any depressive symptoms, with any depressive syndromes, and with major depressive disorder. The contribution of the positive SCS subscales of self-kindness, common humanity, and mindfulness to the variance in depressive symptomatology was almost negligible. However, when combined to a "self-compassion composite", the positive SCS subscales significantly moderated the relationship between "self-coldness" and depressive symptoms in the general population. This speaks for self-compassion having the potential to buffer self-coldness related to depression--providing an argument for interventions that foster self-caring, kind, and forgiving attitudes towards oneself. PMID:26430893

  16. Revictimization of Violence Suffered by Those Diagnosed with Alcohol Dependence in the General Population

    PubMed Central

    Quintana, M. I.; Bressan, R. A.; Mello, M. F.; Andreoli, S. B.

    2015-01-01

    Objective. To verify the association between violence and alcohol dependence syndrome in sample populations. Method. Population-wide survey with multistage probabilistic sample. 3,744 individuals of both genders, aged from 15 to 75 years, were interviewed from the cities of São Paulo and Rio de Janeiro using the Composite International Diagnostic Interview (CIDI 2.1). Results. In both cities, alcohol dependence was associated with the male gender, having suffered violence related to criminality, and having suffered familial violence. In both cities, urban violence, in more than 50% of cases, and familial violence, in more than 90% of cases, preceded alcohol dependence. The reoccurrence of traumatic events occurred in more than half of individuals dependent on alcohol. In São Paulo, having been diagnosed with PTSD is associated with violence revictimization (P = 0.014; Odds = 3.33). Conclusion. Alcohol dependence syndrome is complexly related to urban and familial violence in the general population. Violence frequently precedes alcoholism, but this relationship is dependent on residence and traumatic events. This vicious cycle contributes to perpetuating the high rates of alcoholism and violence in the cities. Politicians ordering the reduction of violence in the large metropolises can, potentially, reduce alcoholism and contribute to the break of this cycle. PMID:26000304

  17. Global population trajectories of tunas and their relatives.

    PubMed

    Juan-Jordá, Maria José; Mosqueira, Iago; Cooper, Andrew B; Freire, Juan; Dulvy, Nicholas K

    2011-12-20

    Tunas and their relatives dominate the world's largest ecosystems and sustain some of the most valuable fisheries. The impacts of fishing on these species have been debated intensively over the past decade, giving rise to divergent views on the scale and extent of the impacts of fisheries on pelagic ecosystems. We use all available age-structured stock assessments to evaluate the adult biomass trajectories and exploitation status of 26 populations of tunas and their relatives (17 tunas, 5 mackerels, and 4 Spanish mackerels) from 1954 to 2006. Overall, populations have declined, on average, by 60% over the past half century, but the decline in the total adult biomass is lower (52%), driven by a few abundant populations. The trajectories of individual populations depend on the interaction between life histories, ecology, and fishing pressure. The steepest declines are exhibited by two distinct groups: the largest, longest lived, highest value temperate tunas and the smaller, short-lived mackerels, both with most of their populations being overexploited. The remaining populations, mostly tropical tunas, have been fished down to approximately maximum sustainable yield levels, preventing further expansion of catches in these fisheries. Fishing mortality has increased steadily to the point where around 12.5% of the tunas and their relatives are caught each year globally. Overcapacity of these fisheries is jeopardizing their long-term sustainability. To guarantee higher catches, stabilize profits, and reduce collateral impacts on marine ecosystems requires the rebuilding of overexploited populations and stricter management measures to reduce overcapacity and regulate threatening trade. PMID:22143785

  18. Global population trajectories of tunas and their relatives

    PubMed Central

    Juan-Jordá, Maria José; Mosqueira, Iago; Cooper, Andrew B.; Freire, Juan; Dulvy, Nicholas K.

    2011-01-01

    Tunas and their relatives dominate the world's largest ecosystems and sustain some of the most valuable fisheries. The impacts of fishing on these species have been debated intensively over the past decade, giving rise to divergent views on the scale and extent of the impacts of fisheries on pelagic ecosystems. We use all available age-structured stock assessments to evaluate the adult biomass trajectories and exploitation status of 26 populations of tunas and their relatives (17 tunas, 5 mackerels, and 4 Spanish mackerels) from 1954 to 2006. Overall, populations have declined, on average, by 60% over the past half century, but the decline in the total adult biomass is lower (52%), driven by a few abundant populations. The trajectories of individual populations depend on the interaction between life histories, ecology, and fishing pressure. The steepest declines are exhibited by two distinct groups: the largest, longest lived, highest value temperate tunas and the smaller, short-lived mackerels, both with most of their populations being overexploited. The remaining populations, mostly tropical tunas, have been fished down to approximately maximum sustainable yield levels, preventing further expansion of catches in these fisheries. Fishing mortality has increased steadily to the point where around 12.5% of the tunas and their relatives are caught each year globally. Overcapacity of these fisheries is jeopardizing their long-term sustainability. To guarantee higher catches, stabilize profits, and reduce collateral impacts on marine ecosystems requires the rebuilding of overexploited populations and stricter management measures to reduce overcapacity and regulate threatening trade. PMID:22143785

  19. Simulations of accretion disks in pseudo-complex General Relativity

    NASA Astrophysics Data System (ADS)

    Hess, P. O.; Algalán B., M.; Schönenbach, T.; Greiner, W.

    2015-11-01

    After a summary on pseudo-complex General Relativity (pc-GR), circular orbits and stable orbits in general are discussed, including predictions compared to observations. Using a modified version of a model for accretions disks, presented by Page and Thorne in 1974, we apply the raytracing technique in order to simulate the appearance of an accretion disk as it should be observed in a detector. In pc-GR we predict a dark ring near a very massive, rapidly rotating object.

  20. Comparison of General Population, Patient, and Carer Utility Values for Dementia Health States

    PubMed Central

    Mulhern, Brendan; Banerjee, Sube; Tait, Rhian; Watchurst, Caroline; Smith, Sarah C.; Young, Tracey A.; Knapp, Martin; Brazier, John E.

    2015-01-01

    Utility values to estimate quality-adjusted life years (QALYs) for use in cost-utility analyses are usually elicited from members of the general population. Public attitudes and understanding of dementia in particular may mean that values elicited from the general population may differ from patients and carers for dementia health states. This study examines how the population impacts utility values elicited for dementia health states using interviewer-administered time tradeoff valuation of health states defined by the dementia-specific preference-based measures DEMQOL-U (patient-report) and DEMQOL-Proxy-U (carer-report). Eight DEMQOL-U states were valued by 78 members of the UK general population and 71 patients with dementia of mild severity. Eight DEMQOL-Proxy-U states were valued by 77 members of the UK general population and 71 carers of patients with dementia of mild severity. Random-effects generalized least squares regression estimated the impact of population, dementia health state, and respondent sociodemographic characteristics on elicited values, finding that values for dementia health states differed by population and that the difference varied across dementia health states. Patients with dementia and carers of patients with dementia gave systematically lower values than members of the general population that were not due to differences in the sociodemographic characteristics of the populations. Our results suggest that the population used to produce dementia health state values could impact the results of cost-utility analyses and potentially affect resource allocation decisions; yet, currently, only general population values are available for usage. PMID:25385749

  1. Quaternionic quantization principle in general relativity and supergravity

    NASA Astrophysics Data System (ADS)

    Kober, Martin

    2016-01-01

    A generalized quantization principle is considered, which incorporates nontrivial commutation relations of the components of the variables of the quantized theory with the components of the corresponding canonical conjugated momenta referring to other space-time directions. The corresponding commutation relations are formulated by using quaternions. At the beginning, this extended quantization concept is applied to the variables of quantum mechanics. The resulting Dirac equation and the corresponding generalized expression for plane waves are formulated and some consequences for quantum field theory are considered. Later, the quaternionic quantization principle is transferred to canonical quantum gravity. Within quantum geometrodynamics as well as the Ashtekar formalism, the generalized algebraic properties of the operators describing the gravitational observables and the corresponding quantum constraints implied by the generalized representations of these operators are determined. The generalized algebra also induces commutation relations of the several components of the quantized variables with each other. Finally, the quaternionic quantization procedure is also transferred to 𝒩 = 1 supergravity. Accordingly, the quantization principle has to be generalized to be compatible with Dirac brackets, which appear in canonical quantum supergravity.

  2. Canonical quantization of general relativity in discrete space-times.

    PubMed

    Gambini, Rodolfo; Pullin, Jorge

    2003-01-17

    It has long been recognized that lattice gauge theory formulations, when applied to general relativity, conflict with the invariance of the theory under diffeomorphisms. We analyze discrete lattice general relativity and develop a canonical formalism that allows one to treat constrained theories in Lorentzian signature space-times. The presence of the lattice introduces a "dynamical gauge" fixing that makes the quantization of the theories conceptually clear, albeit computationally involved. The problem of a consistent algebra of constraints is automatically solved in our approach. The approach works successfully in other field theories as well, including topological theories. A simple cosmological application exhibits quantum elimination of the singularity at the big bang. PMID:12570532

  3. Dispersal patterns of red foxes relative to population density

    USGS Publications Warehouse

    Allen, S.H.; Sargeant, A.B.

    1993-01-01

    Factors affecting red fox (Vulpes vulpes) dispersal patterns are poorly understood but warranted investigation because of the role of dispersal in rebuilding depleted populations and transmission of diseases. We examined dispersal patterns of red foxes in North Dakota based on recoveries of 363 of 854 foxes tagged as pups and relative to fox density. Foxes were recovered up to 8.6 years after tagging; 79% were trapped or shot. Straight-line distances between tagging and recovery locations ranged from 0 to 302 km. Mean recovery distances increased with age and were greater for males than females, but longest individual recovery distances were by females. Dispersal distances were not related to population density for males (P = 0.36) or females (P = 0.96). The proportion of males recovered that dispersed was inversely related to population density (r = -0.94; n = 5; P = 0.02), but not the proportion of females (r = -0.49; n = 5; P = 0.40). Dispersal directions were not uniform for either males (P = 0.003) or females (P = 0.006); littermates tended to disperse in similar directions (P = 0.09). A 4-lane interstate highway altered dispersal directions (P = 0.001). Dispersal is a strong innate behavior of red foxes (especially males) that results in many individuals of both sexes traveling far from natal areas. Because dispersal distance was unaffected by fox density, populations can be rebuilt and diseases transmitted long distances regardless of fox abundance.

  4. Worldwide F(ST) estimates relative to five continental-scale populations.

    PubMed

    Steele, Christopher D; Court, Denise Syndercombe; Balding, David J

    2014-11-01

    We estimate the population genetics parameter FST (also referred to as the fixation index) from short tandem repeat (STR) allele frequencies, comparing many worldwide human subpopulations at approximately the national level with continental-scale populations. FST is commonly used to measure population differentiation, and is important in forensic DNA analysis to account for remote shared ancestry between a suspect and an alternative source of the DNA. We estimate FST comparing subpopulations with a hypothetical ancestral population, which is the approach most widely used in population genetics, and also compare a subpopulation with a sampled reference population, which is more appropriate for forensic applications. Both estimation methods are likelihood-based, in which FST is related to the variance of the multinomial-Dirichlet distribution for allele counts. Overall, we find low FST values, with posterior 97.5 percentiles < 3% when comparing a subpopulation with the most appropriate population, and even for inter-population comparisons we find FST < 5%. These are much smaller than single nucleotide polymorphism-based inter-continental FST estimates, and are also about half the magnitude of STR-based estimates from population genetics surveys that focus on distinct ethnic groups rather than a general population. Our findings support the use of FST up to 3% in forensic calculations, which corresponds to some current practice. PMID:26460400

  5. A general temporal data model and the structured population event history register

    PubMed Central

    Clark, Samuel J.

    2010-01-01

    At this time there are 37 demographic surveillance system sites active in sub-Saharan Africa, Asia and Central America, and this number is growing continuously. These sites and other longitudinal population and health research projects generate large quantities of complex temporal data in order to describe, explain and investigate the event histories of individuals and the populations they constitute. This article presents possible solutions to some of the key data management challenges associated with those data. The fundamental components of a temporal system are identified and both they and their relationships to each other are given simple, standardized definitions. Further, a metadata framework is proposed to endow this abstract generalization with specific meaning and to bind the definitions of the data to the data themselves. The result is a temporal data model that is generalized, conceptually tractable, and inherently contains a full description of the primary data it organizes. Individual databases utilizing this temporal data model can be customized to suit the needs of their operators without modifying the underlying design of the database or sacrificing the potential to transparently share compatible subsets of their data with other similar databases. A practical working relational database design based on this general temporal data model is presented and demonstrated. This work has arisen out of experience with demographic surveillance in the developing world, and although the challenges and their solutions are more general, the discussion is organized around applications in demographic surveillance. An appendix contains detailed examples and working prototype databases that implement the examples discussed in the text. PMID:20396614

  6. Doppler frequency in interplanetary radar and general relativity

    NASA Technical Reports Server (NTRS)

    Mcvittie, G. C.

    1972-01-01

    The change of frequency of an interplanetary radar signal sent from the earth to another planet or to a space probe is worked out according to general relativity. The Schwarzschild spacetime is employed and its null geodesics control the motion of the signals. Exact Doppler frequency formulas are derived for one-way and two-way radar in terms of an arbitrary Schwarzschild radial coordinate. A reduction to the special relativity case is used to interpret the formulas in terms of the relative radial velocity of emitter and target. The general relativity corrections are worked out approximately for each of three possible Schwarzschild radial coordinates, and a numerical example is given. The amount of the correction is different according as one or the other of the Schwarzschild coordinates is identified with the radius vector deduced from classical celestial mechanics. The identification problem is discussed.

  7. High rates of sexual behavior in the general population: correlates and predictors.

    PubMed

    Långström, Niklas; Hanson, R Karl

    2006-02-01

    We studied 2450, 18-60-year-old men and women from a 1996 national survey of sexuality and health in Sweden to identify risk factors and correlates of elevated rates of sexual behavior (hypersexuality) in a representative, non-clinical population. Interviews and questionnaires measured various sexual behaviors, developmental risk factors, behavioral problems, and health indicators. The results suggested that correlates of high rates of intercourse were mostly positive, whereas the correlates of high rates of masturbation and impersonal sex were typically undesirable. For both men and women, high rates of impersonal sex were related to separation from parents during childhood, relationship instability, sexually transmitted disease, tobacco smoking, substance abuse, and dissatisfaction with life in general. The association between hypersexuality and paraphilic sexual interests (exhibitionism, voyeurism, masochism/sadism) was particularly and equally strong for both genders (odds ratios of 4.6-25.6). The results held, with a few exceptions, when controlling for age, being in a stable relationship, living in a major city, and same-sex sexual orientation. We conclude that elevated rates of impersonal sex are associated with a range of negative health indicators in the general population. PMID:16502152

  8. Non-inertial Frames in Special and General Relativity

    NASA Astrophysics Data System (ADS)

    Lusanna, Luca

    A theory of global non-inertial frames in special relativity is developed by taking into account relativistic metrology and by avoiding the coordinate singularities of the rotating disk and of Fermi coordinates. Then this theory is used in general relativity for the treatment of globally hyperbolic, asymptotically Minkowskian space-times solution of Einstein's equations. Also some comments on the problem of dark matter, connecting it to the relativistic metrology used in astrophysics, are made.

  9. Testing the Foundations of the Foundations of General Relativity

    NASA Astrophysics Data System (ADS)

    Lämmerzahl, Claus

    2010-07-01

    General Relativity is based on the Einstein Equivalence Principle consisting of the Universality of Free Fall, the Universality of the Gravitational Redshift and Local Lorentz Invariance. Stating these principles already employs some further underlying assumptions. These assumptions are related to the famous Newton's axioms. Accordingly, the existence of inertial systems, the form of the equation of motion and of the law of reciprocal action will be discussed in this article. Conditions are given which allow to test these underlying assumptions.

  10. Unimodular metagravity vs. general relativity with a scalar field

    SciTech Connect

    Pirogov, Yu. F.

    2010-01-15

    The unimodular metagravity, with the graviscalar as a dark matter, is compared with General Relativity (GR) in the presence of a scalar field. The effect of the graviscalar on the static spherically symmetric metric is studied. An exact limit solution representing a new cosmic object, the (harmonic) graviscalar black hole, is given. The relation with the black hole in the environment of a scalar field in GR is discussed.

  11. Age related flow rate nomograms in a normal pediatric population.

    PubMed

    Gaum, L D; Wese, F X; Liu, T P; Wong, A K; Hardy, B E; Churchill, B M

    1989-01-01

    Uroflow studies in a normal pediatric population were analysed statistically. Single studies for 511 subjects (272 boys and 239 girls) were reviewed. Nomograms relating peak flow to volume voided and age were established. An acceptable lower limit for peak flow was obtained from the data and a volume voided range was calculated so that both criteria could be used with 90% probability to define the normal voiding situation. The mean values of peak flow rate increased with volume voided in both sexes and also with age in the male population. Different sets of nomograms, which are necessary for daily clinical evaluation, are given. They define the normal values in the normal population. PMID:2763925

  12. Generalized entropies and logarithms and their duality relations

    PubMed Central

    Hanel, Rudolf; Thurner, Stefan; Gell-Mann, Murray

    2012-01-01

    For statistical systems that violate one of the four Shannon–Khinchin axioms, entropy takes a more general form than the Boltzmann–Gibbs entropy. The framework of superstatistics allows one to formulate a maximum entropy principle with these generalized entropies, making them useful for understanding distribution functions of non-Markovian or nonergodic complex systems. For such systems where the composability axiom is violated there exist only two ways to implement the maximum entropy principle, one using escort probabilities, the other not. The two ways are connected through a duality. Here we show that this duality fixes a unique escort probability, which allows us to derive a complete theory of the generalized logarithms that naturally arise from the violation of this axiom. We then show how the functional forms of these generalized logarithms are related to the asymptotic scaling behavior of the entropy. PMID:23129618

  13. Related General-Vocabulary Knowledge Transfers to Learning Technical Terms

    ERIC Educational Resources Information Center

    Balch, William R.

    2015-01-01

    In a classroom experiment during the first week of an introductory psychology course, randomly assigned students received a pretest and then a brief training on the definitions of general-vocabulary words either related (e.g., "facilitation") or unrelated (e.g., "rendition") to 16 technical terms (e.g., "social…

  14. Generalization of Moll Ross relations for heterojunction bipolar transistors

    NASA Astrophysics Data System (ADS)

    Mohammad, S. Noor

    2002-04-01

    Moll-Ross relations for the current flow through the base region of a bipolar transistor, and for the base transit time, have been generalized for heterojunction bipolar transistors with a nonuniform energy bandgap in the base region. The effect of both heavy doping and carrier degeneracy has been taken into account.

  15. Factors Affecting the Relative Efficiency of General Acid Catalysis

    ERIC Educational Resources Information Center

    Kwan, Eugene E.

    2005-01-01

    A simple framework for evaluating experimental kinetic data to provide support for Specific Acid Catalysis (SAC) and General Acid Catalysis (GAC) is described based on the factors affecting their relative efficiency. Observations reveal that increasing the SAC-to-GAC rate constant ratio reduces the effective pH range for GAC.

  16. Spinning fluids in general relativity. II - Self-consistent formulation

    NASA Technical Reports Server (NTRS)

    Ray, John R.; Smalley, Larry, L.; Krisch, Jean P.

    1987-01-01

    Methods used earlier to derive the equations of motion for a spinning fluid in the Einstein-Cartan theory are specialized to the case of general relativity. The main idea is to include the spin as a thermodynamic variable in the theory.

  17. Probing Students' Understanding of Some Conceptual Themes in General Relativity

    ERIC Educational Resources Information Center

    Bandyopadhyay, Atanu; Kumar, Arvind

    2010-01-01

    This work is an attempt to see how physics undergraduates view the basic ideas of general relativity when they are exposed to the topic in a standard introductory course. Since the subject is conceptually and technically difficult, we adopted a "case studies" approach, focusing in depth on about six students who had just finished a one semester…

  18. Stationarity of extremum entropy fluid bodies in general relativity

    NASA Astrophysics Data System (ADS)

    Schiffrin, Joshua Seth

    We consider perfect fluid bodies ("stars'') in general relativity that are axisymmetric, asymptotically flat, and that admit a maximal hypersurface. We show that configurations that extremize the total entropy at fixed ADM mass, ADM angular momentum, and total particle number are stationary with circular flow. For such stars, this establishes that thermodynamic equilibrium implies dynamic equilibrium.

  19. Stationarity of extremum entropy fluid bodies in general relativity

    NASA Astrophysics Data System (ADS)

    Schiffrin, Joshua S.

    2015-09-01

    We consider perfect fluid bodies (‘stars’) in general relativity that are axisymmetric, asymptotically flat, and that admit a maximal hypersurface. We show that configurations that extremize the total entropy at fixed ADM mass, ADM angular momentum, and total particle number are stationary with circular flow. For such stars, this establishes that thermodynamic equilibrium implies dynamic equilibrium.

  20. Chern-Simons modified general relativity: Conserved charges

    SciTech Connect

    Tekin, Bayram

    2008-01-15

    We construct the conserved charges (mass and angular momentum) of the Chern-Simons modified general relativity in asymptotically flat and anti-de Sitter (AdS) spacetimes. Our definition is based on background Killing symmetries and reduces to the known expressions in the proper limits.

  1. Evidence for a General ADHD Factor from a Longitudinal General School Population Study

    ERIC Educational Resources Information Center

    Normand, Sebastien; Flora, David B.; Toplak, Maggie E.; Tannock, Rosemary

    2012-01-01

    Recent factor analytic studies in Attention-Deficit/Hyperactivity Disorder (ADHD) have shown that hierarchical models provide a better fit of ADHD symptoms than correlated models. A hierarchical model includes a general ADHD factor and specific factors for inattention, and hyperactivity/impulsivity. The aim of this 12-month longitudinal study was…

  2. Sign Language Users' Education and Employment Levels: Keeping Pace with Changes in the General Australian Population?

    ERIC Educational Resources Information Center

    Willoughby, Louisa

    2011-01-01

    This article draws on data from the 2006 Australian census to explore the education and employment outcomes of sign languages users living in Victoria, Australia, and to compare them with outcomes reported in the general population. Census data have the advantage of sampling the entire population on the one night, avoiding problems of population…

  3. Assessment of occupational exposures in a general population: comparison of different methods

    PubMed Central

    Tielemans, E.; Heederik, D.; Burdorf, A.; Vermeulen, R.; Veulemans, H.; Kromhout, H.; Hartog, K.

    1999-01-01

    OBJECTIVES: To evaluate the relative merits of job specific questionnaires and various alternative assessment methods of occupational exposures often used in general population studies. METHODS: Subjects were participants in a hospital based case-control study of risk factors for male infertility. Estimates of exposure to organic solvents and chromium, based on job specific questionnaires, generic questionnaires, self reports of exposure, an external job exposure matrix (JEM), and a population specific JEM were compared with passive diffuse dosimeter results and measurements in urine. Urine samples from the end of the shift were analysed for metabolites of toluene, xylene, several glycol ethers, trichloroethylene, and chromium. Passive dosimeter date, metabolites of specific solvents, and urinary chromium concentrations were available for 89, 267, and 156 subjects, respectively. The alternative methods and measurements in urine were compared by means of the Cohen's kappa statistic and by computing the positive predictive value, sensitivity, and specificity of the alternative methods against measurements in urine. RESULTS: Passive dosimeter results indicated that exposure classifications with job specific questionnaire information could discriminate between high and low exposures. The kappa coefficients were < 0.4, so agreement between the various methods and measurements in urine was poor. Sensitivity of the methods ranged from 0.21 to 0.85, whereas specificity ranged from 0.34 to 0.94. Positive predictive values ranged from 0.19 to 0.58, with the highest values for job specific questionnaires. CONCLUSIONS: The results indicate that the implementation of job specific questionnaires in a general population study might be worth the extra expense it entails, bearing in mind the paramount importance of avoiding false positive exposure estimates when exposure prevalence is low.   PMID:10448321

  4. Genetic Determinants of Age-Related Macular Degeneration in Diverse Populations From the PAGE Study

    PubMed Central

    Restrepo, Nicole A.; Spencer, Kylee L.; Goodloe, Robert; Garrett, Tiana A.; Heiss, Gerardo; Bůžková, Petra; Jorgensen, Neal; Jensen, Richard A.; Matise, Tara C.; Hindorff, Lucia A.; Klein, Barbara E. K.; Klein, Ronald; Wong, Tien Y.; Cheng, Ching-Yu; Cornes, Belinda K.; Tai, E.-Shyong; Ritchie, Marylyn D.; Haines, Jonathan L.; Crawford, Dana C.

    2014-01-01

    Purpose. Substantial progress has been made in identifying susceptibility variants for AMD in European populations; however, few studies have been conducted to understand the role these variants play in AMD risk in diverse populations. The present study aims to examine AMD risk across diverse populations in known and suspected AMD complement factor and lipid-related loci. Methods. Targeted genotyping was performed across study sites for AMD and lipid trait-associated single nucleotide polymorphism (SNPs). Genetic association tests were performed at individual sites and then meta-analyzed using logistic regression assuming an additive genetic model stratified by self-described race/ethnicity. Participants included cases with early or late AMD and controls with no signs of AMD as determined by fundus photography. Populations included in this study were European Americans, African Americans, Mexican Americans, and Singaporeans from the Population Architecture using Genomics and Epidemiology (PAGE) study. Results. Index variants of AMD, rs1061170 (CFH) and rs10490924 (ARMS2), were associated with AMD at P = 3.05 × 10−8 and P = 6.36 × 10−6, respectively, in European Americans. In general, none of the major AMD index variants generalized to our non-European populations with the exception of rs10490924 in Mexican Americans at an uncorrected P value < 0.05. Four lipid-associated SNPS (LPL rs328, TRIB1 rs6987702, CETP rs1800775, and KCTD10/MVK rs2338104) were associated with AMD in African Americans and Mexican Americans (P < 0.05), but these associations did not survive strict corrections for multiple testing. Conclusions. While most associations did not generalize in the non-European populations, variants within lipid-related genes were found to be associated with AMD. This study highlights the need for larger well-powered studies in non-European populations. PMID:25205864

  5. An interesting consequence of the general principle of relativity

    NASA Astrophysics Data System (ADS)

    Grøn, Øyvind; Jemterud, Torkild

    2016-04-01

    We show that Einstein's general theory of relativity, together with the assumption that the principle of relativity encompasses rotational motion, predicts that in a flat Friedmann-Lemaitre-Robertson-Walker (FLRW) universe model with dust and Lorentz Invariant Vacuum Energy (LIVE), the density parameter of vacuum energy must have the value Ω_{Λ 0}=0.737. The physical mechanism connecting the relativity of rotational motion with the energy density of dark energy is the inertial dragging effect. The predicted value is necessary in order to have perfect inertial dragging, which is required for rotational motion to be relative. If one accepts that due to the impossibility of defining motion for a single particle in an otherwise empty universe, the universe must be constructed so that all types of motion are relative, then this solves the so-called cosmological constant problem.

  6. Higher mortality due to intracerebral hemorrhage in dialysis patients: a comparison with the general population in Japan.

    PubMed

    Wakasugi, Minako; Matsuo, Koji; Kazama, Junichiro James; Narita, Ichiei

    2015-02-01

    Cerebrovascular diseases, including intracerebral hemorrhage, cerebral infarction, and subarachnoid hemorrhage, remain prevalent causes of morbidity and mortality among dialysis patients. Their mortality rate for cerebrovascular diseases is roughly three times higher than that in the general population. However, whether mortality rates for all subtypes of cerebrovascular diseases are equally higher has not been evaluated. The aim of this study was to determine the mortality rate for each stroke subtype, comparing dialysis patients and the general population in Japan. We used mortality data reported by the Japanese Society for Dialysis Therapy and national Vital Statistics data between 2008 and 2009. We calculated standardized mortality ratios and compared the mortality rates for stroke subtypes including intracerebral hemorrhage, cerebral infarction, and subarachnoid hemorrhage. During the 2-year study period, 51 994 and 933 deaths from intracerebral hemorrhage, 79 124 and 511 deaths from cerebral infarction, and 24 957 and 147 deaths from subarachnoid hemorrhage were recorded per 252 million person-years and per 546 474 dialysis patient-years, respectively. Standardized mortality ratios among dialysis patients relative to the general population were 3.8 (95% confidence interval, 3.6-4.1), 1.3 (1.2-1.4), and 1.3 (1.1-1.6) for intracerebral hemorrhage, cerebral infarction, and subarachnoid hemorrhage, respectively. Intracerebral hemorrhage was the highest cause of mortality in the dialysis population, although cerebral infarction was the highest in the general population. Relative to the general population in Japan, Japanese dialysis patients had higher mortality rates, especially for intracerebral hemorrhage. PMID:25196294

  7. Natural course of 500 consecutive cases of whooping cough: a general practice population study.

    PubMed Central

    Jenkinson, D.

    1995-01-01

    OBJECTIVE--To describe the natural course of whooping cough. DESIGN--Observational study of a general practice population. SETTING--Discrete semirural East Midlands practice of 11,500 patients. SUBJECTS--500 consecutive cases of whooping cough diagnosed clinically during 1977-92. MAIN OUTCOME MEASURES--Incidence of vomiting, whooping, apnoea, admission to hospital, and complications; duration and frequency of paroxysms. Pattern of spread. RESULTS--The incidence in the practice population was 4347/100,000 population compared with a notification rate for England and Wales of 717/100,000. Most cases were relatively mild. 284 patients vomited after paroxysms, 242 whooped, and 57 had apnoea. Duration and frequency of paroxysms varied widely. Female and unimmunised patients suffered more severe disease. Bordetella was isolated from fewer immunised patients (24/96 v 63/122 unimmunised). Infection was usually spread through contacts with someone with clinical whooping cough. Five patients developed pneumonia, three of whom had been immunised. Three patients required hospital admission. CONCLUSIONS--Most cases of whooping cough are relatively mild. Such cases are difficult to diagnose without a high index of suspicion because doctors are unlikely to hear the characteristic cough, which may be the only symptom. Parents can be reassured that a serious outcome is unlikely. Adults also get whooping cough, especially from their children, and get the same symptoms as children. The difficulty of early diagnosis and probability of missed cases reinforces the need to keep the incidence low through immunisation in order to protect infants, who are the most vulnerable. PMID:7866173

  8. Periodontitis Is Associated with Endothelial Dysfunction in a General Population: A Cross-Sectional Study

    PubMed Central

    Holtfreter, Birte; Empen, Klaus; Gläser, Sven; Lorbeer, Roberto; Völzke, Henry; Ewert, Ralf; Kocher, Thomas; Dörr, Marcus

    2013-01-01

    A large body of evidence underlines an association between periodontal disease and cardiovascular disease. In contrast, data on its relation with endothelial dysfunction as a marker of early subclinical atherosclerosis is inconclusive and limited to patient-cohort studies. We therefore investigated the association between periodontal disease and flow-mediated dilation of the brachial artery (FMD) as a measure of endothelial dysfunction in a general population, and also addressed a possible mediation via inflammation. The study population comprised 1,234 subjects (50.5% men) aged 25–85 years from the 5-year follow-up of the Study of Health in Pomerania, a population-based cohort study. Clinical attachment loss (CAL) and pocket probing depth (PPD) as measures of periodontal disease were assessed half-mouth at four sites per tooth. Subjects were classified according to the periodontitis case definition proposed by Tonetti and Claffey (2005). Measurements of FMD and nitroglycerin-mediated dilation (NMD) were performed using standardized ultrasound techniques. High-sensitive C-reactive protein, fibrinogen and leukocyte count were measured. Fully adjusted multivariate linear regression analyses revealed significant associations of the percentage of sites with PPD ≥6 mm with FMD (ptrend=0.048), with subjects within the highest category having a 0.74% higher FMD compared to subjects within the lowest category (p<0.05). Consistently, FMD values increased significantly across categories of the percentage of sites with CAL ≥6 mm (ptrend=0.01) and the periodontitis case definition (ptrend=0.006). Restrictions to subjects without antihypertensive or statin medication or current non-smokers confirmed previous results. Systemic inflammation did not seem to mediate the relation. Both PPD and CAL were not consistently associated with NMD. In contrast to previous studies, high levels of periodontal disease were significantly associated with high FMD values. This association

  9. 10 CFR 61.41 - Protection of the general population from releases of radioactivity.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 2 2012-01-01 2012-01-01 false Protection of the general population from releases of radioactivity. 61.41 Section 61.41 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Performance Objectives § 61.41 Protection of the general...

  10. 10 CFR 61.41 - Protection of the general population from releases of radioactivity.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 2 2011-01-01 2011-01-01 false Protection of the general population from releases of radioactivity. 61.41 Section 61.41 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Performance Objectives § 61.41 Protection of the general...

  11. 10 CFR 61.41 - Protection of the general population from releases of radioactivity.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Protection of the general population from releases of radioactivity. 61.41 Section 61.41 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Performance Objectives § 61.41 Protection of the general...

  12. 10 CFR 61.41 - Protection of the general population from releases of radioactivity.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 2 2013-01-01 2013-01-01 false Protection of the general population from releases of radioactivity. 61.41 Section 61.41 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Performance Objectives § 61.41 Protection of the general...

  13. 10 CFR 61.41 - Protection of the general population from releases of radioactivity.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 2 2014-01-01 2014-01-01 false Protection of the general population from releases of radioactivity. 61.41 Section 61.41 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Performance Objectives § 61.41 Protection of the general...

  14. Health Benefits for Vocational Rehabilitation Consumers: Comparison of Access Rates with Workers in the General Population

    ERIC Educational Resources Information Center

    Lustig, Daniel C.; Strauser, David R.

    2010-01-01

    Access to health insurance is one of the critical aspects of securing employment for people with disabilities. This study investigated whether vocational rehabilitation consumers secured employment with an employer who offered health insurance at similar rates to workers in the general population. In general, the results show that vocational…

  15. The Factor Structure of ADHD in a General Population of Primary School Children

    ERIC Educational Resources Information Center

    Ullebo, Anne Karin; Breivik, Kyrre; Gillberg, Christopher; Lundervold, Astri J.; Posserud, Maj-Britt

    2012-01-01

    Objective: To examine whether a bifactor model with a general ADHD factor and domain specific factors of inattention, hyperactivity and impulsivity was supported in a large general population sample of children. We also explored the utility of forming subscales based on the domain-specific factors. Methods: Child mental health questionnaires were…

  16. Towards the quasi-localization of canonical general relativity

    NASA Astrophysics Data System (ADS)

    Szabados, László B.

    2009-06-01

    A general framework for a systematic quasi-localization of canonical general relativity and a new ingredient, the requirement of the gauge invariance of the boundary terms appearing in the calculation of Poisson brackets, are given. As a consequence of this it is shown, in particular, that the generator vector fields (built from the lapse and shift) of the quasi-local quantities must be divergence free with respect to a Sen-type connection, and the volume form induced from the spatial metric on the boundary surface must be fixed. Talk given at the Conference on Recent Results in Mathematical Relativity, The Erwin Schrödinger Institute, Vienna, 20-21 August 2008, and dedicated to Bobby Beig on the occasion of his 60th birthday.

  17. Testing General Relativity with the Shadow Size of Sgr A(*).

    PubMed

    Johannsen, Tim; Broderick, Avery E; Plewa, Philipp M; Chatzopoulos, Sotiris; Doeleman, Sheperd S; Eisenhauer, Frank; Fish, Vincent L; Genzel, Reinhard; Gerhard, Ortwin; Johnson, Michael D

    2016-01-22

    In general relativity, the angular radius of the shadow of a black hole is primarily determined by its mass-to-distance ratio and depends only weakly on its spin and inclination. If general relativity is violated, however, the shadow size may also depend strongly on parametric deviations from the Kerr metric. Based on a reconstructed image of Sagittarius A^{*} (Sgr A^{*}) from a simulated one-day observing run of a seven-station Event Horizon Telescope (EHT) array, we employ a Markov chain Monte Carlo algorithm to demonstrate that such an observation can measure the angular radius of the shadow of Sgr A^{*} with an uncertainty of ∼1.5  μas (6%). We show that existing mass and distance measurements can be improved significantly when combined with upcoming EHT measurements of the shadow size and that tight constraints on potential deviations from the Kerr metric can be obtained. PMID:26849580

  18. Testing General Relativity with the Shadow Size of Sgr A*

    NASA Astrophysics Data System (ADS)

    Johannsen, Tim; Broderick, Avery E.; Plewa, Philipp M.; Chatzopoulos, Sotiris; Doeleman, Sheperd S.; Eisenhauer, Frank; Fish, Vincent L.; Genzel, Reinhard; Gerhard, Ortwin; Johnson, Michael D.

    2016-01-01

    In general relativity, the angular radius of the shadow of a black hole is primarily determined by its mass-to-distance ratio and depends only weakly on its spin and inclination. If general relativity is violated, however, the shadow size may also depend strongly on parametric deviations from the Kerr metric. Based on a reconstructed image of Sagittarius A* (Sgr A* ) from a simulated one-day observing run of a seven-station Event Horizon Telescope (EHT) array, we employ a Markov chain Monte Carlo algorithm to demonstrate that such an observation can measure the angular radius of the shadow of Sgr A* with an uncertainty of ˜1.5 μ as (6%). We show that existing mass and distance measurements can be improved significantly when combined with upcoming EHT measurements of the shadow size and that tight constraints on potential deviations from the Kerr metric can be obtained.

  19. Some Links Between General Relativity and Other Parts of Physics

    NASA Astrophysics Data System (ADS)

    Gibbons, Gary W.

    Now that General Relativity has become such a central part of modern physics, its geometrical formalism being taught as part of almost all undergraduate physics courses, it is natural to ask: how can its basic concepts and techniques be used to illuminate areas of physics which have no connection with gravity? Another way of asking this question is: are the analogues situations to those occurring in General Relativity? The search for such analogues is of course an old one, but recently, because of advances in technology, these questions have become more topical. In this talk I will illustrate this theme by examples drawn from optics, acoustics, liquid crystals, graphene and the currently popular topic of cloaking.

  20. A century of general relativity: astrophysics and cosmology.

    PubMed

    Blandford, R D

    2015-03-01

    One hundred years after its birth, general relativity has become a highly successful physical theory in the sense that it has passed a large number of experimental and observational tests and finds extensive application to a wide variety of cosmic phenomena. It remains an active area of research as new tests are on the way, epitomized by the exciting prospect of detecting gravitational waves from merging black holes. General relativity is the essential foundation of the standard model of cosmology and underlies our description of the black holes and neutron stars that are ultimately responsible for the most powerful and dramatic cosmic sources. Its interface with physics on the smallest and largest scales will continue to provide fertile areas of investigation in its next century. PMID:25745165

  1. General Theory of Relativity: Will It Survive the Next Decade?

    NASA Technical Reports Server (NTRS)

    Bertolami, Orfeu; Paramos, Jorge; Turyshev, Slava G.

    2006-01-01

    The nature of gravity is fundamental to our understanding of our own solar system, the galaxy and the structure and evolution of the Universe. Einstein's general theory of relativity is the standard model that is used for almost ninety years to describe gravitational phenomena on these various scales. We review the foundations of general relativity, discuss the recent progress in the tests of relativistic gravity, and present motivations for high-accuracy gravitational experiments in space. We also summarize the science objectives and technology needs for the laboratory experiments in space with laboratory being the entire solar system. We discuss the advances in our understanding of fundamental physics anticipated in the near future and evaluate discovery potential for the recently proposed gravitational experiments.

  2. A century of general relativity: Astrophysics and cosmology

    NASA Astrophysics Data System (ADS)

    Blandford, R. D.

    2015-03-01

    One hundred years after its birth, general relativity has become a highly successful physical theory in the sense that it has passed a large number of experimental and observational tests and finds extensive application to a wide variety of cosmic phenomena. It remains an active area of research as new tests are on the way, epitomized by the exciting prospect of detecting gravitational waves from merging black holes. General relativity is the essential foundation of the standard model of cosmology and underlies our description of the black holes and neutron stars that are ultimately responsible for the most powerful and dramatic cosmic sources. Its interface with physics on the smallest and largest scales will continue to provide fertile areas of investigation in its next century.

  3. Macrostate equivalence of two general ensembles and specific relative entropies

    NASA Astrophysics Data System (ADS)

    Mori, Takashi

    2016-08-01

    The two criteria of ensemble equivalence, i.e., macrostate equivalence and measure equivalence, are investigated for a general pair of states. Macrostate equivalence implies the two ensembles are indistinguishable by the measurement of macroscopic quantities obeying the large-deviation principle, and measure equivalence means that the specific relative entropy of these two states vanishes in the thermodynamic limit. It is shown that measure equivalence implies a macrostate equivalence for a general pair of states by deriving an inequality connecting the large-deviation rate functions to the specific relative Renyi entropies. The result is applicable to both quantum and classical systems. As applications, a sufficient condition for thermalization, the time scale of quantum dynamics of macrovariables, and the second law with strict irreversibility in a quantum quench are discussed.

  4. Sensor failure detection using generalized parity relations for flexible structures

    NASA Technical Reports Server (NTRS)

    Mercadal, Mathieu

    1989-01-01

    Analytical redundancy may be preferable to hardware redundancy in failure detection/isolation tasks for such large-scale systems as space structures. Generalized single-sensor parity relations are presently applied to this problem; they are noted to yield a very simple isolation logic, and their generation is found to be extremely rapid, even in the case of extremely complex systems, provided only that the eigenstructure of the system be known. Their implementation is, however, extremely sensitive to modeling errors and noise.

  5. GENERAL RELATIVITY DERIVATION OF BEAM REST-FRAME HAMILTONIAN.

    SciTech Connect

    WEI,J.

    2001-06-18

    Analysis of particle interaction in the laboratory frame of storage rings is often complicated by the fact that particle motion is relativistic, and that reference particle trajectory is curved. Rest frame of the reference particle is a convenient coordinate system to work with, within which particle motion is non-relativistic. We have derived the equations of motion in the beam rest frame from the general relativity formalism, and have successfully applied them to the analysis of crystalline beams [1].

  6. Exploring the transition from special to general relativity

    NASA Astrophysics Data System (ADS)

    Semon, Mark D.; Malin, Shimon; Wortel, Stephanie

    2009-05-01

    In a previous paper we discussed two examples of circular motion which are especially useful in relativity courses because they lead to predictions verified by experiments with macroscopic objects. We analyzed these examples by considering motion around an N-gon and then taking the limit as N →∞ and the N-gon becomes a circle. In this paper we use the same approach to illustrate how generalizing special relativity to a theory that includes non-inertial frames can lead to a non-Euclidean geometry. We also derive two properties of clocks at rest in a reference frame traveling on a circular path.

  7. The effects of general relativity on near-earth satellites

    NASA Technical Reports Server (NTRS)

    Ries, J. C.; Watkins, M. M.; Tapley, B. D.; Huang, C.

    1990-01-01

    Whether one uses a solar system barycentric frame or a geocentric frame when including the general theory of relativity in orbit determination for near-earth satellites, the results should be equivalent to some limiting accuracy. The purpose of this paper is to clarify the effects of relativity in each frame and to demonstrate their equivalence through the analysis of three years of laser tracking data taken on the Lageos satellite. It is demonstrated that the simpler formulation in the geocentric frame is adequate for the purpose of near-earth satellite orbit determination. A correction to the conventional barycentric equations of motion is shown to be required.

  8. Language Generativity, Response Generalization, and Derived Relational Responding

    PubMed Central

    Stewart, Ian; McElwee, John; Ming, Siri

    2013-01-01

    Language generativity can be described as the ability to produce sentences never before said, and to understand sentences never before heard. One process often cited as underlying language generativity is response generalization. However, though the latter seems to promise a technical understanding of the former at a process level, an investigation of definitions and approaches to the term “response generalization” that appear in the literature suggests that it does not do so. We argue that a more promising candidate for the role of key process underlying language generativity is derived relational responding. We introduce the latter concept and describe empirical research showing its connection with language. We subsequently present a relational frame theory (RFT) conceptualization of derived relations as contextually controlled generalized relational responding. We then review a series of recent studies on derived manding in developmentally delayed children and adults that arguably demonstrate the applied utility of a derived relations-based approach with respect to the phenomenon of generative language. PMID:23814374

  9. Tests of general relativity from timing the double pulsar.

    PubMed

    Kramer, M; Stairs, I H; Manchester, R N; McLaughlin, M A; Lyne, A G; Ferdman, R D; Burgay, M; Lorimer, D R; Possenti, A; D'Amico, N; Sarkissian, J M; Hobbs, G B; Reynolds, J E; Freire, P C C; Camilo, F

    2006-10-01

    The double pulsar system PSR J0737-3039A/B is unique in that both neutron stars are detectable as radio pulsars. They are also known to have much higher mean orbital velocities and accelerations than those of other binary pulsars. The system is therefore a good candidate for testing Einstein's theory of general relativity and alternative theories of gravity in the strong-field regime. We report on precision timing observations taken over the 2.5 years since its discovery and present four independent strong-field tests of general relativity. These tests use the theory-independent mass ratio of the two stars. By measuring relativistic corrections to the Keplerian description of the orbital motion, we find that the "post-Keplerian" parameter s agrees with the value predicted by general relativity within an uncertainty of 0.05%, the most precise test yet obtained. We also show that the transverse velocity of the system's center of mass is extremely small. Combined with the system's location near the Sun, this result suggests that future tests of gravitational theories with the double pulsar will supersede the best current solar system tests. It also implies that the second-born pulsar may not have formed through the core collapse of a helium star, as is usually assumed. PMID:16973838

  10. Explanatory and illustrative visualization of special and general relativity.

    PubMed

    Weiskopf, Daniel; Borchers, Marc; Ertl, Thomas; Falk, Martin; Fechtig, Oliver; Frank, Regine; Grave, Frank; King, Andreas; Kraus, Ute; Müller, Thomas; Nollert, Hans-Peter; Rica Mendez, Isabel; Ruder, Hanns; Schafhitzel, Tobias; Schär, Sonja; Zahn, Corvin; Zatloukal, Michael

    2006-01-01

    This paper describes methods for explanatory and illustrative visualizations used to communicate aspects of Einstein's theories of special and general relativity, their geometric structure, and of the related fields of cosmology and astrophysics. Our illustrations target a general audience of laypersons interested in relativity. We discuss visualization strategies, motivated by physics education and the didactics of mathematics, and describe what kind of visualization methods have proven to be useful for different types of media, such as still images in popular science magazines, film contributions to TV shows, oral presentations, or interactive museum installations. Our primary approach is to adopt an egocentric point of view: The recipients of a visualization participate in a visually enriched thought experiment that allows them to experience or explore a relativistic scenario. In addition, we often combine egocentric visualizations with more abstract illustrations based on an outside view in order to provide several presentations of the same phenomenon. Although our visualization tools often build upon existing methods and implementations, the underlying techniques have been improved by several novel technical contributions like image-based special relativistic rendering on GPUs, special relativistic 4D ray tracing for accelerating scene objects, an extension of general relativistic ray tracing to manifolds described by multiple charts, GPU-based interactive visualization of gravitational light deflection, as well as planetary terrain rendering. The usefulness and effectiveness of our visualizations are demonstrated by reporting on experiences with, and feedback from, recipients of visualizations and collaborators. PMID:16805261

  11. Gravitation experiments at Stanford. [using general relativity theory

    NASA Technical Reports Server (NTRS)

    Lipa, J. A.

    1980-01-01

    The experimental situation in post-Newtonian gravitation is briefly reviewed in order to reexamine the extent to which experiment supports or refutes general relativity. A description is given of the equivalence principle project, the gyroscope experiment, and the search for gravity waves. It is noted that even though some doubt has been cast on the value of the perihelion advance and the gravitational redshift as precise tests of general relativity in the past few years, many competing theories have been ruled out; in particular, the results from the Viking mission significantly reduce the credibility of the Brans-Dicke theory (Brans and Dicke, 1961). The dimensionless constant omega in this theory is now forced to exceed 50, while the value originally proposed was 6 (omega being infinity in general relativity). It is noted that the gyro experiment described is capable of putting much tighter limits on this parameter, and together with the other experiments in progress will help place gravitational theory on a firmer experimental footing.

  12. Constraints on a new post-general relativity cosmological parameter

    NASA Astrophysics Data System (ADS)

    Caldwell, Robert; Cooray, Asantha; Melchiorri, Alessandro

    2007-07-01

    A new cosmological variable is introduced to characterize the degree of departure from Einstein’s general relativity with a cosmological constant. The new parameter, ϖ, is the cosmological analog of γ, the parametrized post-Newtonian variable which measures the amount of spacetime curvature per unit mass. In the cosmological context, ϖ measures the difference between the Newtonian and longitudinal potentials in response to the same matter sources, as occurs in certain scalar-tensor theories of gravity. Equivalently, ϖ measures the scalar shear fluctuation in a dark-energy component. In the context of a vanilla, cosmological constant-dominated universe, a nonzero ϖ signals a departure from general relativity or a fluctuating cosmological constant. Using a phenomenological model for the time evolution ϖ=ϖ0ρDE/ρM which depends on the ratio of energy density in the cosmological constant to the matter density at each epoch, it is shown that the observed cosmic microwave background temperature anisotropies limit the overall normalization constant to be -0.4<ϖ0<0.1 at the 95% confidence level. Existing measurements of the cross-correlations of the cosmic microwave background with large-scale structure further limit ϖ0>-0.2 at the 95% CL. In the future, integrated Sachs-Wolfe and weak lensing measurements can more tightly constrain ϖ0, providing a valuable clue to the nature of dark energy and the validity of general relativity.

  13. Flaws in Black Hole Theory and General Relativity

    NASA Astrophysics Data System (ADS)

    Crothers, Stephen J.

    2014-03-01

    Alleged black hole models pertain to a universe that is spatially infinite, is eternal, contains only one mass, is not expanding, and is asymptotically flat or asymptotically not flat. But the alleged big bang cosmology pertains to a universe that is spatially finite (one case) or spatially infinite (two different cases), is of finite age, contains radiation and many masses including multiple black holes (some of which are primordial), is expanding, and is not asymptotically anything. Thus the black hole and the big bang contradict one another - they are mutually exclusive. It is surprisingly easy to prove that neither General Relativity nor Newton's theory predicts the black hole. Despite numerous claims for discovery of black holes in their millions, nobody has ever actually found one. It is also not difficult to prove that General Relativity violates the usual conservation of energy and momentum. Fundamentally there are contradictions contained in black hole theory, big bang cosmology, and General Relativity. Numerical methods are therefore to no avail.

  14. Prevalence of STI related consultations in general practice: results from the second Dutch National Survey of General Practice

    PubMed Central

    van Bergen, Jan EAM; Kerssens, Jan J; Schellevis, Francois G; Sandfort, Theo G; Coenen, Ton J; Bindels, Patrick J

    2006-01-01

    Background The role of the GP in the care of sexually transmitted infections (STIs) is unclear. Aim We studied the prevalence of STI related consultations in Dutch general practice in order to obtain insight into the contribution of the GP in STI control. Design of study A descriptive study. Setting The study took place within the framework of the second Dutch National Survey of General Practice in 2001, a large nationally representative population-based survey. Method During 1 year, data of all patient contacts with the participating GPs were recorded in electronic medical records. Contacts for the same health problem were clustered into disease episodes and their diagnosis coded according to the International Classification of Primary Care. All STI and STI related episodes were analysed. Results In total, 1 524 470 contacts of 375 899 registered persons in 104 practices were registered during 1 year and 2460 STI related episodes were found. The prevalence rate of STI was 39 per 10 000 persons and of STI/HIV related questions 23 per 10 000. More than half of all STIs were found in highly urbanised areas and STIs were overrepresented in deprived areas. Three quarters of all STIs diagnosed in the Netherlands are made in general practice. An important number of other reproductive health visits in general practice offer opportunities for meaningful STI counselling and tailored prevention. Discussion GPs contribute significantly to STI control, see the majority of patients with STI related symptoms and questions and are an important player in STI care. In particular, GPs in urban areas and inner-city practices should be targeted for accelerated sexual health programmes. PMID:16464323

  15. Prevalence of impairments, disabilities, handicaps and quality of life in the general population: a review of recent literature.

    PubMed Central

    Barbotte, E.; Guillemin, F.; Chau, N.

    2001-01-01

    OBJECTIVE: To determine the prevalence rates of morbidity in the general population through bibliographic research. METHODS: Articles relating to impairment, disability, handicap, quality of life and their prevalence in the general population, published between January 1990 and March 1998, were selected on the MEDLINE database. FINDINGS: The 20 articles retained out of 433 used 41 different indicators. Indicators of impairment, disability, handicap and low quality of life showed prevalence rates of 0.1-92%, 3.6-66%, 0.6-56% and 1.8-26% respectively, depending on age and the accuracy of indicators. The heterogeneity of the conceptual framework and insufficient recognition of the importance of indicator accuracy, the age factor and the socioeconomic characteristics of the studied populations impede reliable international comparison. CONCLUSION: Further standardization of indicators is therefore required. The revision of the International Classification of Impairments, Disabilities and Handicaps may make it possible to resolve some of the difficulties encountered. PMID:11731812

  16. A walk-in screening of dementia in the general population in Taiwan.

    PubMed

    Chen, Chun-Hung; Wang, Ling-Chun; Ma, Tzu-Chiao; Yang, Yuan-Han

    2014-01-01

    Alzheimer's disease (AD) has increased in its prevalence due to the increasing aged population. Currently there is no updated data on the prevalence of dementia including its very mild stage in Taiwan. Under the extensive coverage of Mentality Protection Center (MPC), Fo Guang Shan, Taiwan, the volunteers of MPC have conducted the medicine-related services and the screening of dementia by AD8 (ascertainment of dementia 8) that can screen the dementia even at its very mild stage in general population in all Taiwan. From 2011 to 2013, in total, 2,171 participants, 368 in the northern, 549 in the central, 877 in the southern, and 377 in the eastern part, were recruited with the mean age being 66.9 ± 10.2 years old. The ratio of suspected dementia patients, AD8 score greater than or equal to 2, was 13.6% of all recruited participants with their mean AD8 score being 2.9 ± 1.3, mean age being 69.4 ± 10.8 years old, and female predominance being 73.0%. Although this is a screening study, it has extensive coverage of all Taiwan and the use of AD8 is capable of screening very mild dementia. A further study with a randomized sampling to examine the prevalence and incidence of dementia including its very mild stage is encouraged. PMID:24883363

  17. The Energy-Momentum Problem in General Relativity

    NASA Astrophysics Data System (ADS)

    Xulu, S. S.

    2003-08-01

    Energy-momentum is an important conserved quantity whose definition has been a focus of many investigations in general relativity. Unfortunately, there is still no generally accepted definition of energy and momentum in general relativity. Attempts aimed at finding a quantity for describing distribution of energy-momentum due to matter, non-gravitational and gravitational fields resulted in various energy-momentum complexes whose physical meaning have been questioned. The problems associated with energy-momentum complexes resulted in some researchers even abandoning the concept of energy-momentum localization in favour of the alternative concept of quasi-localization. However, quasi-local masses have their inadequacies, while the remarkable work of Virbhadra and some others, and recent results of Cooperstock and Chang et al. have revived an interest in various energy-momentum complexes. Hence in this work we use energy-momentum complexes to obtain the energy distributions in various space-times. We elaborate on the problem of energy localization in general relativity and use energy-momentum prescriptions of Einstein, Landau and Lifshitz, Papapetrou, Weinberg, and Møller to investigate energy distributions in various space-times. It is shown that several of these energy-momentum complexes give the same and acceptable results for a given space-time. This shows the importance of these energy-momentum complexes. Our results agree with Virbhadra's conclusion that the Einstein's energy-momentum complex is still the best tool for obtaining energy distribution in a given space-time. The Cooperstock hypothesis for energy localization in GR is also supported.

  18. PDRK: A General Kinetic Dispersion Relation Solver for Magnetized Plasma

    NASA Astrophysics Data System (ADS)

    Xie, Huasheng; Xiao, Yong

    2016-02-01

    A general, fast, and effective approach is developed for numerical calculation of kinetic plasma linear dispersion relations. The plasma dispersion function is approximated by J-pole expansion. Subsequently, the dispersion relation is transformed to a standard matrix eigenvalue problem of an equivalent linear system. Numerical solutions for the least damped or fastest growing modes using an 8-pole expansion are generally accurate; more strongly damped modes are less accurate, but are less likely to be of physical interest. In contrast to conventional approaches, such as Newton's iterative method, this approach can give either all the solutions in the system or a few solutions around the initial guess. It is also free from convergence problems. The approach is demonstrated for electrostatic dispersion equations with one-dimensional and two-dimensional wavevectors, and for electromagnetic kinetic magnetized plasma dispersion relation for bi-Maxwellian distribution with relative parallel velocity flows between species. supported by the National Magnetic Confinement Fusion Science Program of China (Nos. 2015GB110003, 2011GB105001, 2013GB111000), National Natural Science Foundation of China (No. 91130031), the Recruitment Program of Global Youth Experts

  19. Hamiltonian General Relativity in Finite Space and Cosmological Potential Perturbations

    NASA Astrophysics Data System (ADS)

    Barbashov, B. M.; Pervushin, V. N.; Zakharov, A. F.; Zinchuk, V. A.

    The Hamiltonian formulation of general relativity is considered in finite space-time and a specific reference frame given by the diffeo-invariant components of the Fock simplex in terms of the Dirac-ADM variables. The evolution parameter and energy invariant with respect to the time-coordinate transformations are constructed by the separation of the cosmological scale factor a(x0) and its identification with the spatial averaging of the metric determinant, so that the dimension of the kinemetric group of diffeomorphisms coincides with the dimension of a set of variables whose velocities are removed by the Gauss-type constraints in accordance with the second Nöther theorem. This coincidence allows us to solve the energy constraint, fulfil Dirac's Hamiltonian reduction, and to describe the potential perturbations in terms of the Lichnerowicz scale-invariant variables distinguished by the absence of the time derivatives of the spatial metric determinant. It was shown that the Hamiltonian version of the cosmological perturbation theory acquires attributes of the theory of superfluid liquid, and it leads to a generalization of the Schwarzschild solution. The astrophysical application of this approach to general relativity is considered under supposition that the Dirac-ADM Hamiltonian frame is identified with that of the Cosmic Microwave Background radiation distinguished by its dipole component in the frame of an Earth observer.

  20. Testing general relativity using golden black-hole binaries

    NASA Astrophysics Data System (ADS)

    Ghosh, Abhirup; Ghosh, Archisman; Johnson-McDaniel, Nathan K.; Mishra, Chandra Kant; Ajith, Parameswaran; Del Pozzo, Walter; Nichols, David A.; Chen, Yanbei; Nielsen, Alex B.; Berry, Christopher P. L.; London, Lionel

    2016-07-01

    The coalescences of stellar-mass black-hole binaries through their inspiral, merger, and ringdown are among the most promising sources for ground-based gravitational-wave (GW) detectors. If a GW signal is observed with sufficient signal-to-noise ratio, the masses and spins of the black holes can be estimated from just the inspiral part of the signal. Using these estimates of the initial parameters of the binary, the mass and spin of the final black hole can be uniquely predicted making use of general-relativistic numerical simulations. In addition, the mass and spin of the final black hole can be independently estimated from the merger-ringdown part of the signal. If the binary black-hole dynamics is correctly described by general relativity (GR), these independent estimates have to be consistent with each other. We present a Bayesian implementation of such a test of general relativity, which allows us to combine the constraints from multiple observations. Using kludge modified GR waveforms, we demonstrate that this test can detect sufficiently large deviations from GR and outline the expected constraints from upcoming GW observations using the second-generation of ground-based GW detectors.

  1. Sexually coercive behavior in male youth: population survey of general and specific risk factors.

    PubMed

    Kjellgren, Cecilia; Priebe, Gisela; Svedin, Carl Göran; Långström, Niklas

    2010-10-01

    Little is known about risk/protective factors for sexually coercive behavior in general population youth. We used a Swedish school-based population survey of sexual attitudes and experiences (response rate 77%) and investigated literature-based variables across sexually coercive (SEX), non-sexual conduct problem (CP), and normal control (NC) participants to identify general and specific risk/protective factors for sexual coercion. Among 1,933 male youth, 101 (5.2%) reported sexual coercion (ever talked or forced somebody into genital, oral, or anal sex) (SEX), 132 (6.8%) were classified as CP, and the remaining 1,700 (87.9%) as NC. Of 29 tested variables, 25 were more common in both SEX and CP compared to NC youth, including minority ethnicity, separated parents, vocational study program, risk-taking, aggressiveness, depressive symptoms, substance abuse, sexual victimization, extensive sexual experiences, and sexual preoccupation. When compared to CP youth only, SEX youth more often followed academic study programs, used less drugs and were less risk-taking. Further, SEX more frequently than CP youth reported gender stereotypic and pro-rape attitudes, sexual preoccupation, prostitution, and friends using violent porn. Finally, in a multivariate logistic regression, academic study program, pro-rape attitudes, sexual preoccupation, and less risk-taking independently remained more strongly associated with SEX compared to CP offending. In conclusion, several sociodemographic, family, and individual risk/protective factors were common to non-sexual and sexually coercive antisocial behavior in late adolescence. However, pro-rape cognitions, and sexual preoccupation, were sexuality-related, specific risk factors. The findings could inform preventive efforts and the assessment and treatment of sexually coercive male youth. PMID:19888644

  2. The Burden and Determinants of Neck Pain in the General Population

    PubMed Central

    van der Velde, Gabrielle; Carroll, Linda J.; Holm, Lena W.; Cassidy, J. David; Guzman, Jamie; Côté, Pierre; Haldeman, Scott; Ammendolia, Carlo; Carragee, Eugene; Hurwitz, Eric; Nordin, Margareta; Peloso, Paul

    2008-01-01

    Study Design Best evidence synthesis. Objective To undertake a best evidence synthesis of the published evidence on the burden and determinants of neck pain and its associated disorders in the general population. Summary of Background Data The evidence on burden and determinants of neck has not previously been summarized. Methods The Bone and Joint Decade 2000−2010 Task Force on Neck Pain and Its Associated Disorders performed a systematic search and critical review of literature published between 1980 and 2006 to assemble the best evidence on neck pain. Studies meeting criteria for scientific validity were included in a best evidence synthesis. Results We identified 469 studies on burden and determinants of neck pain, and judged 249 to be scientifically admissible; 101 articles related to the burden and determinants of neck pain in the general population. Incidence ranged from 0.055 per 1000 person years (disc herniation with radiculopathy) to 213 per 1000 persons (self-reported neck pain). Incidence of neck injuries during competitive sports ranged from 0.02 to 21 per 1000 exposures. The 12-month prevalence of pain typically ranged between 30% and 50%; the 12-month prevalence of activity-limiting pain was 1.7% to 11.5%. Neck pain was more prevalent among women and prevalence peaked in middle age. Risk factors for neck pain included genetics, poor psychological health, and exposure to tobacco. Disc degeneration was not identified as a risk factor. The use of sporting gear (helmets, face shields) to prevent other types of injury was not associated with increased neck injuries in bicycling, hockey, or skiing. Conclusion Neck pain is common. Nonmodifiable risk factors for neck pain included age, gender, and genetics. Modifiable factors included smoking, exposure to tobacco, and psychological health. Disc degeneration was not identified as a risk factor. Future research should concentrate on longitudinal designs exploring preventive strategies and modifiable risk

  3. Brominated flame retardants - Exposure and risk assessment for the general population.

    PubMed

    Fromme, H; Becher, G; Hilger, B; Völkel, W

    2016-01-01

    Brominated flame retardants (BFRs) are a large group of different substances used in numerous products to prevent fire hazards. Some of them are persistent in the environment, accumulate in the food chain and are of toxicological concern, while for others current data are limited. Meanwhile, BFRs have been found in many environmental media, foods, and biota including humans. This review presents recent findings obtained from monitoring data in environmental media relevant for human exposure, as well as dietary exposure. In this context, concentrations in indoor and ambient air and in house dust are outlined. Furthermore, we summarize human biomonitoring data on BFR levels in blood and breast milk. Current estimates of the overall exposure of the general population using different relevant subsets are also addressed. All of these data are discussed in relation to currently available toxicological reference values used for risk assessment purposes. Obviously, the exposure of the general population varies considerably in different parts of the world and even within countries. Polybrominated diphenyl ethers (PBDEs) and hexabromocyclododecane (HBCD) show the highest intake during infancy. While the highest intake for BDE 47 for all groups was observed in the US, the total BDE 209 and HBCD intake was highest in the UK. For HBCD and all PBDEs except BDE 209, diet accounts for a large proportion of the total intake during infancy in all countries. With regard to toddlers and adults, the contribution of diet to total intake is high in Germany and the UK, while in the US, the high concentrations of PBDE in dust resulted in a notably smaller proportion of the intake being attributed to diet. PMID:26412400

  4. Diagnostic health risk assessment of electronic waste on the general population in developing countries' scenarios

    SciTech Connect

    Frazzoli, Chiara; Orisakwe, Orish Ebere; Dragone, Roberto; Mantovani, Alberto

    2010-11-15

    E-waste is the generic name for technological waste. Even though aspects related to e-waste environmental pollution and human exposure are known, scientific assessments are missing so far on the actual risks for health sustainability of the general population exposed to e-waste scenarios, such as illicit dumping, crude recycling and improper treatment and disposal. In fact, further to occupational and direct local exposure, e-waste scenarios may impact on the environment-to-food chain, thus eliciting a widespread and repeated exposure of the general population to mixtures of toxicants, mainly toxic chemical elements, polycyclic aromatic hydrocarbons and persistent organic pollutants. In the absence of any clear policy on e-waste flow management, the situation in the e-waste receiver countries may become quite scary; accordingly, here we address a diagnostic risk assessment of health issues potentially elicited by e-waste related mixtures of toxicants. Scientific evidence available so far (mainly from China) is discussed with special attention to the concept of health sustainability, i.e. the poor health burden heritage perpetuated through the mother-to-child dyad. Endocrine disruption and neurotoxicity are specifically considered as examples of main health burden issues relevant to perpetuation through life cycle and across generations; toxicological information are considered along with available data on environmental and food contamination and human internal exposure. The risk from exposure to e-waste related mixtures of toxicants of vulnerable subpopulation like breast-fed infants is given special attention. The diagnostic risk assessment demonstrates how e-waste exposure poses an actual public health emergency, as it may entrain significant health risks also for generations to come. Exposure scenarios as well as specific chemicals of major concern may vary in different contexts; for instance, only limited information is available on e-waste related exposures in

  5. Hyperbolicity of physical theories with application to general relativity

    NASA Astrophysics Data System (ADS)

    Hilditch, David; Richter, Ronny

    2016-08-01

    We consider gauge theories from the free evolution point of view, in which initial data satisfying constraints of a theory are given, and because the constraints satisfy a closed evolution system, they remain so. We study a model constrained Hamiltonian theory and identify a particular structure in the equations of motion which we call the standard gauge freedom. The pure gauge subsystem of this model theory is identified, and the manner in which the gauge variables couple to the field equations is presented. We demonstrate that the set of gauge choices that can be coupled to the field equations to obtain a strongly hyperbolic formulation is exactly the set of strongly hyperbolic pure gauges. Consequently we analyze a parametrized family of formulations of general relativity. The generalization of the harmonic gauge formulation to a five parameter family of gauge conditions is obtained.

  6. Structures of general relativity in dilaton-Maxwell electrodynamics

    NASA Astrophysics Data System (ADS)

    Kechkin, O. V.; Mosharev, P. A.

    2016-08-01

    It is shown that electro (magneto) static sector of Maxwell’s electrodynamics coupled to the dilaton field in a string theory form possesses the symmetry group of the stationary General Relativity in vacuum. Performing the Ernst formalism, we develope a technique for generation of exact solutions in this modified electrodynamics on the base of the normalized Ehlers symmetry transformation. In the electrostatic case, we construct and study a general class of spherically symmetric solutions that describes a pointlike source of the Coulomb type. It is demonstrated that this source is characterized by finite and singularity-free interaction at short distances. Also it is established that the total electrostatic energy of this source is finite and inversely proportional to the dilaton-Maxwell coupling constant.

  7. Guidelines for composite materials research related to general aviation aircraft

    NASA Technical Reports Server (NTRS)

    Dow, N. F.; Humphreys, E. A.; Rosen, B. W.

    1983-01-01

    Guidelines for research on composite materials directed toward the improvement of all aspects of their applicability for general aviation aircraft were developed from extensive studies of their performance, manufacturability, and cost effectiveness. Specific areas for research and for manufacturing development were identified and evaluated. Inputs developed from visits to manufacturers were used in part to guide these evaluations, particularly in the area of cost effectiveness. Throughout the emphasis was to direct the research toward the requirements of general aviation aircraft, for which relatively low load intensities are encountered, economy of production is a prime requirement, and yet performance still commands a premium. A number of implications regarding further directions for developments in composites to meet these requirements also emerged from the studies. Chief among these is the need for an integrated (computer program) aerodynamic/structures approach to aircraft design.

  8. A Generalized Relational Schema for an Integrated Clinical Patient Database

    PubMed Central

    Friedman, Carol; Hripcsak, George; Johnson, Stephen B.; Cimino, James J.; Clayton, Paul D.

    1990-01-01

    Patient data is central to a Clinical Information System (CIS). The organization of the data in a patient database is essential to the functioning of the system. If the CIS contains a medical decision support component, further requirements are imposed on the database. It must be capable of accurately representing a broad range of clinical information in coded form, and be organized for efficient retrievals by patient, time, and type of clinical term. This paper presents a generalized schema for a clinical patient database within the relational database model. The general design makes it possible to represent diverse clinical data in a standard structure and to organize the data so that it is densely clustered by patient and time.

  9. Psychometric properties of a Spanish version of the Beck Anxiety Inventory (BAI) in general population.

    PubMed

    Magán, Inés; Sanz, Jesús; García-Vera, María Paz

    2008-11-01

    This is the first study that provides normative, reliability, factor validity and discriminant validity data of the Beck Anxiety Inventory (BAI; Beck, Epstein, Brown, & Steer, 1988) in the Spanish general population, Sanz and Navarro's (2003) Spanish version of the BAI was administered to 249 adults. Factor analyses suggested that the BAI taps a general anxiety dimension comprising two related factors (somatic and affective-cognitive symptoms), but these factors hardly explained any additional variance and, therefore, little information is lost in considering only full-scale scores. Internal consistency estimate for the BAI was high (alpha = .93). The BAI was correlated .63 with the BDI-II and .32 with the Trait-Anger scale of the STAXI 2, but a factor analysis of their items revealed three factors, suggesting that the correlations between the instruments may be better accounted for by relationships between anxiety, depression, and anger, than by problems of discriminant validity. The mean BAI total score and the distribution of BAI scores were similar to those found in other countries. BAI norm scores for the community sample were provided from the total sample and from the male and female subsamples, as females scored higher than males. The utility of these scores for assessing clinical significance of treatment outcomes for anxiety is discussed. PMID:18988448

  10. Quality of life after surgery for rectal cancer: a systematic review of comparisons with the general population.

    PubMed

    Giandomenico, Francesca; Gavaruzzi, Teresa; Lotto, Lorella; Del Bianco, Paola; Barina, Andrea; Perin, Alessandro; Pucciarelli, Salvatore

    2015-01-01

    Rectal cancer treatments may impact negatively on patients' bowel and sexual functions and, in turn, on health-related quality of life. Information on the likely effects of treatment is essential in order to facilitate the care process and the adaptation of patients to their condition. Studies that report on the comparison between rectal cancer patients and the general population are a useful source of this evidence, providing elements to aid in answering questions such as 'is my life going to be the same as before?' In this article, the authors have systematically reviewed articles published in the last 6 years that report on the comparison between rectal patients' and the general population's health-related quality of life. Sixteen out of 645 articles were included. The results are summarized and critically discussed. PMID:26197061

  11. Traffic-related air pollution and risk for leukaemia of an adult population.

    PubMed

    Raaschou-Nielsen, Ole; Ketzel, Matthias; Harbo Poulsen, Aslak; Sørensen, Mette

    2016-03-01

    Air pollution causes lung cancer, but associations with other cancers have not been established. We investigated whether long-term exposure to traffic-related air pollution is associated with the risk of the general population for leukaemia. We identified 1,967 people in whom leukaemia was diagnosed in 1992-2010 from a nation-wide cancer registry and selected 3,381 control people at random, matched on sex and year of birth, from the entire Danish population. Residential addresses since 1971 were traced in a population registry, and outdoor concentrations of NOx and NO2 , as indicators of traffic-related air pollution, were calculated at each address in a dispersion model. We used conditional logistic regression to estimate the risk for leukaemia after adjustment for income, educational level, cohabitation status and co-morbidity. In linear analyses, we found odds ratios for acute myeloid leukaemia of 1.20 (95% confidence interval: 1.04-1.38) per 20 µg/m(3) increase in NOx and 1.31 (1.02-1.68) per 10 µg/m(3) increase in NO2 , calculated as time-weighted average exposure at all addresses since 1971. We found no association with chronic myeloid or lymphocytic leukaemia. This study indicates an association between long-term exposure to traffic-related air pollution and acute myeloid leukaemia in the general population, but not for other subtypes of leukaemia. PMID:26415047

  12. Testing General Relativity and gravitational physics using the LARES satellite

    NASA Astrophysics Data System (ADS)

    Ciufolini, Ignazio; Paolozzi, Antonio; Pavlis, Erricos; Ries, John; Gurzadyan, Vahe; Koenig, Rolf; Matzner, Richard; Penrose, Roger; Sindoni, Giampiero

    2012-11-01

    The discovery of the accelerating expansion of the Universe, thought to be driven by a mysterious form of "dark energy" constituting most of the Universe, has further revived the interest in testing Einstein's theory of General Relativity. At the very foundation of Einstein's theory is the geodesic motion of a small, structureless test-particle. Depending on the physical context, a star, planet or satellite can behave very nearly like a test-particle, so geodesic motion is used to calculate the advance of the perihelion of a planet's orbit, the dynamics of a binary pulsar system and of an Earth-orbiting satellite. Verifying geodesic motion is then a test of paramount importance to General Relativity and other theories of fundamental physics. On the basis of the first few months of observations of the recently launched satellite LARES, its orbit shows the best agreement of any satellite with the test-particle motion predicted by General Relativity. That is, after modelling its known non-gravitational perturbations, the LARES orbit shows the smallest deviations from geodesic motion of any artificial satellite: its residual mean acceleration away from geodesic motion is less than 0.5×10^{-12} m/s^2. LARES-type satellites can thus be used for accurate measurements and for tests of gravitational and fundamental physics. Already with only a few months of observation, LARES provides smaller scatter in the determination of several low-degree geopotential coefficients (Earth gravitational deviations from sphericity) than available from observations of any other satellite or combination of satellites.

  13. Personality comparison of airline pilot incumbents, applicants, and the general population norms on the 16PF.

    PubMed

    Wakcher, Sandra; Cross, Kara; Blackman, Melinda C

    2003-06-01

    Personality comparisons using Cattell's 16PF were made between 137 pilot incumbents, 81 pilot applicants, and the general population norms. No significant differences were found between the scores on the personality factors for the Pilot Incumbents and the Pilot Applicants. Further, the incumbents and applicants who had previous military training versus those who did not had highly similar personalities. However, on nearly every personality factor a significant difference was found between the general population norms and the sample of Pilot Incumbents and Applicants. The Pilot Incumbent/Applicant group scored significantly more intelligent, emotionally stable, and mature in comparison to the general population norms. We believe that it is the high-risk nature of this occupation that leads applicants, wishing to pursue this field, to assess very carefully their own person-job fit and self-select themselves, thus ultimately producing this very distinct "pilot personality profile" described in 1995 by Bartram. PMID:12841441

  14. FLRW non-singular cosmological model in general relativity

    NASA Astrophysics Data System (ADS)

    Jas Pacif, Shibesh Kumar; Mishra, Bivudutta

    2015-12-01

    A singularity free cosmological model is obtained in a homogeneous and isotropic background with a specific form of the Hubble parameter in the presence of an interacting dark energy represented by a time-varying cosmological constant in general relativity. Different cases that arose have been extensively studied for different values of the curvature parameter. Some interesting results have been found with this form of the Hubble parameter to meet the possible negative value of the deceleration parameter ≤ft({ - \\frac{1}{3} ≤slant q < 0} \\right) as the current observations reveal. For some particular values of these parameters, the model reduces to Berman's model.

  15. Derivation of Einstein-Cartan theory from general relativity

    NASA Astrophysics Data System (ADS)

    Petti, Richard

    2016-03-01

    This article presents a derivation of Einstein-Cartan theory from general relativity with no additional assumptions or parameters. The derivation begins with distributions of Kerr masses that converge to a continuum with constant densities of mass, momentum, and angular momentum. The limit includes torsion and the spin-torsion relationship of Einstein-Cartan theory. The construction of curvature and torsion is equivalent to definition of curvature with Cartan forms on fiber bundles. Advantages of Einstein-Cartan theory include accommodating exchange of classical intrinsic and orbital angular momentum and generation of inflation-like expansion in high density cosmological models.

  16. Vector order parameter in general relativity: Covariant equations

    SciTech Connect

    Meierovich, Boris E.

    2010-07-15

    Phase transitions with spontaneous symmetry breaking and vector order parameter are considered in multidimensional theory of general relativity. Covariant equations, describing the gravitational properties of topological defects, are derived. The topological defects are classified in accordance with the symmetry of the covariant derivative of the vector order parameter. The abilities of the derived equations are demonstrated in application to the braneworld concept. New solutions of the Einstein equations with a transverse vector order parameter are presented. In the vicinity of phase transition, the solutions are found analytically.

  17. Rotating black holes in the teleparallel equivalent of general relativity

    NASA Astrophysics Data System (ADS)

    Nashed, Gamal G. L.

    2016-05-01

    We derive set of solutions with flat transverse sections in the framework of a teleparallel equivalent of general relativity which describes rotating black holes. The singularities supported from the invariants of torsion and curvature are explained. We investigate that there appear more singularities in the torsion scalars than in the curvature ones. The conserved quantities are discussed using Einstein-Cartan geometry. The physics of the constants of integration is explained through the calculations of conserved quantities. These calculations show that there is a unique solution that may describe true physical black hole.

  18. Tests of general relativity using Starprobe radio metric tracking data

    NASA Technical Reports Server (NTRS)

    Mease, K. D.; Anderson, J. D.; Wood, L. J.; White, L. K.

    1982-01-01

    The potential of a proposed spacecraft mission, called Starprobe, for testing general relativity and providing information on the interior structure and dynamics of the sun is investigated. Parametric, gravitational perturbation terms are derived which represent relativistic effects and effects due to spatial and temporal variations in the solar potential at a given radial distance. A covariance analysis based on Kalman filtering theory predicts the accuracies with which the free parameters in the perturbation terms can be estimated with radio metric tracking data through the process of trajectory reconstruction. It is concluded that Starprobe can contribute significant information on both the nature of gravitation and the structure and dynamics of the solar interior.

  19. A superconducting gyroscope to test Einstein's general theory of relativity

    NASA Technical Reports Server (NTRS)

    Everitt, C. W. F.

    1978-01-01

    Schiff (1960) proposed a new test of general relativity based on measuring the precessions of the spin axes of gyroscopes in earth orbit. Since 1963 a Stanford research team has been developing an experiment to measure the two effects calculated by Schiff. The gyroscope consists of a uniform sphere of fused quartz 38 mm in diameter, coated with superconductor, electrically suspended and spinning at about 170 Hz in vacuum. The paper describes the proposed flight apparatus and the current state of development of the gyroscope, including techniques for manufacturing and measuring the gyro rotor and housing, generating ultralow magnetic fields, and mechanizing the readout.

  20. Testing general relativity in space-borne and astronomical laboratories

    NASA Technical Reports Server (NTRS)

    Will, Clifford M.

    1989-01-01

    The current status of space-based experiments and astronomical observations designed to test the theory of general relativity is surveyed. Consideration is given to tests of post-Newtonian gravity, searches for feeble short-range forces and gravitomagnetism, improved measurements of parameterized post-Newtonian parameter values, explorations of post-Newtonian physics, tests of the Einstein equivalence principle, observational tests of post-Newtonian orbital effects, and efforts to detect quadrupole and dipole radiation damping. Recent numerical results are presented in tables.

  1. Expanding General Relativity's Space by S-Denying

    NASA Astrophysics Data System (ADS)

    Rabounski, Dmitri; Smarandache, Florentins; Borissova, Larissa

    2016-05-01

    Applying the S-denying procedure to signature conditions in a four-dimensional pseudo-Riemannian space - i.e. changing one (or even all) of the conditions to be partially true and partially false. Obtaining five kinds of expanded space-time for General Relativity. Kind I permits the space-time to be in collapse. Kind II permits the space-time to change its own signature. Kind III has peculiarities, linked to the third signature condition. Kind IV permits regions where the metric fully degenerates: there may be non-quantum teleportation, and a home for virtual photons. Kind V is common for kinds I, II, III, and IV.

  2. Testing General Relativity with Spherical Resonant Mass Detectors

    NASA Astrophysics Data System (ADS)

    Sylvester, Alex J.

    Gravitational waves in f(R) gravity excite monopole and m = 0+/-2 quadrupole resonance modes of a spherical detector. This document reviews the basic ideas of general relativity and gravitational waves, and then applies those concepts to an f( R) gravitational wave. The acoustic response of a GW incident with a spherical detector is reviewed in detail, and the absorption cross section for an f(R) GW impinging on the spherical detector is calculated. Minimum detectable scalar wave amplitudes are explored for the Mario Schenberg detector. The mass of the scalar mode affects its detectability.

  3. Entanglement Entropy from Surface Terms in General Relativity

    NASA Astrophysics Data System (ADS)

    Bhattacharyya, Arpan; Sinha, Aninda

    2013-10-01

    Entanglement entropy in local quantum field theories is typically ultraviolet divergent due to short distance effects in the neighborhood of the entangling region. In the context of gauge/gravity duality, we show that surface terms in general relativity are able to capture this entanglement entropy. In particular, we demonstrate that for 1 + 1-dimensional (1 + 1d) conformal field theories (CFTs) at finite temperature whose gravity dual is Banados-Teitelboim-Zanelli (BTZ) black hole, the Gibbons-Hawking-York term precisely reproduces the entanglement entropy which can be computed independently in the field theory.

  4. Medically Unexplained and Explained Physical Symptoms in the General Population: Association with Prevalent and Incident Mental Disorders

    PubMed Central

    van Eck van der Sluijs, Jonna; ten Have, Margreet; Rijnders, Cees; van Marwijk, Harm; de Graaf, Ron; van der Feltz-Cornelis, Christina

    2015-01-01

    Background Clinical studies have shown that Medically Unexplained Symptoms (MUS) are related to common mental disorders. It is unknown how often common mental disorders occur in subjects who have explained physical symptoms (PHY), MUS or both, in the general population, what the incidence rates are, and whether there is a difference between PHY and MUS in this respect. Aim To study the prevalence and incidence rates of mood, anxiety and substance use disorders in groups with PHY, MUS and combined MUS and PHY compared to a no-symptoms reference group in the general population. Method Data were derived from the Netherlands Mental Health Survey and Incidence Study-2 (NEMESIS-2), a nationally representative face-to-face survey of the general population aged 18-64 years. We selected subjects with explained physical symptoms only (n=1952), with MUS only (n=177), with both MUS and PHY (n=209), and a reference group with no physical symptoms (n=4168). The assessment of common mental disorders was through the Composite International Diagnostic Interview 3.0. Multivariate logistic regression analyses were used to examine the association between group membership and the prevalence and first-incidence rates of comorbid mental disorders, adjusted for socio-demographic characteristics. Results MUS were associated with the highest prevalence rates of mood and anxiety disorders, and combined MUS and PHY with the highest prevalence rates of substance disorder. Combined MUS and PHY were associated with a higher incidence rate of mood disorder only (OR 2.9 (95%CI:1.27,6.74)). Conclusion In the general population, PHY, MUS and the combination of both are related to mood and anxiety disorder, but odds are highest for combined MUS and PHY in relation to substance use disorder. Combined MUS and PHY are related to a greater incidence of mood disorder. These findings warrant further research into possibilities to improve recognition and early intervention in subjects with combined MUS and

  5. BOOK REVIEW: A First Course in General Relativity (Second Edition) A First Course in General Relativity (Second Edition)

    NASA Astrophysics Data System (ADS)

    Poisson, Eric

    2010-05-01

    A few years ago, in my review of Sean Carroll's book in Classical and Quantum Gravity [1], I wrote that while the 1970s was the decade of Weinberg [2] and Misner, Thorne and Wheeler [3], and while the eighties was the decade of Schutz [4] and Wald [5], the 2000s was clearly the decade of Hartle [6] and Carroll [7]. In my opinion, these books continue to stand out in the surprisingly dense crowd of introductory textbooks on general relativity. At the dawn of this new decade I look forward to see what fresh pedagogical insights will be produced next, and who will be revealed as the winners of the 2010s. It is, of course, much too early to tell, but Schutz is back, and he will set the standard just as he did back in 1985. This is the long-awaited second edition of his `First Course', a short, accessible, and very successful introduction to general relativity. The changes from the first edition are modest: Schutz wisely refrained from bloating the text with new topics, and limited himself to updating his discussion of gravitational-wave sources and detectors, neutron-star and black-hole astrophysics, and suggestions for further reading. Most importantly, he completely rewrote the chapter on cosmology, a topic that has evolved enormously since the first edition. The book begins in chapter 1 with a beautiful review of special relativity that emphasizes spacetime geometry and stays away from an algebraic approach based on the Lorentz transformation, which appears only later in the chapter. This is followed up in chapters 2 and 3 with an introduction to vector and tensor analysis in flat spacetime. The point of view is modern (tensors are defined as linear mapping of vectors and one-forms into real numbers) but the presentation is very accessible and avoids an overload of mathematical fine print. In chapter 4 the book introduces the spacetime description of fluids; it is here that the energy-momentum tensor makes its first appearance. The move to curved spacetime is

  6. Some population and related problems in the Ghanaian Economy.

    PubMed

    De Graft-johnson, J C

    1971-01-01

    A detailed review of the present situation of the Ghanaian economy indicates that, in spite of a decrease in the number of people employed in the agricultural sector (which might suggest an increase in agricultural productivity according to the thesis to this effect based on experiences in developed countries), food productivity has failed to improve. This is a serious situation for a population increasing at a rate of 2.7% per year. The large percentage of school-age children (21.8% with 44.5% of the population under 15 years as of 1960) necessitating education expenditures and the heavy immigration from surrounding countries (12% of the population are immigrants and they account for 50% of the male retail traders in the country according to the 1960 census) have created 2 of the largest problems for the country's economy. In 1960, 61.8% of the adult working population was employed in agriculture and agricultural products (primarily cocoa, which accounts for over 60% of this total) yet production lagged behind demand, making Ghana a net importer of food. Future prospects for Ghana's agricultural situation indicate that increase in production (estimated in 1965 at 1.62%) is far behind the estimated necessary increase of 7.7% based on food consumption levels of 1961. Even for cocoa production which had been progressing, the prospects are discouraging due to factors such as insufficient equipment, transportation facilities and other elements related to production maintenance, as well as to a shortage of labor (caused by the Aliens Compliance Order of 1969, the government's effort to reduce the involvement of immigrants in the economy) which has yet to be filled despite high urban unemployment rates and rural underemployment. Although producer prices for cocoa increased, little evidence can be found that this provided incentive for farmers to increase production. This review indicates that the country is still waiting for the agricultural revolution to arrive which

  7. The reliability and validity of the Social Responsiveness Scale in a UK general child population.

    PubMed

    Wigham, Sarah; McConachie, Helen; Tandos, Jonathan; Le Couteur, Ann S

    2012-01-01

    This is the first UK study to report the reliability, validity, and factor structure of the Social Responsiveness Scale (SRS) in a general population sample. Parents of 500 children (aged 5-8 years) in North East England completed the SRS. Profiles of scores were similar to USA norms, and a single factor structure was identified. Good construct validity and internal consistency were found. Children with identified special needs were found to have significantly higher SRS scores than those without. The findings suggest the SRS performs in similar ways in UK and USA general population samples of children and can be used without modification in the UK. PMID:22277583

  8. Testing general relativity with Landers on the Martian satellite Phobos

    NASA Technical Reports Server (NTRS)

    Anderson, J. D.; Borderies, N. J.; Campbell, J. K.; Dunne, J. A.; Ellis, J.

    1989-01-01

    A planned experiment to obtain range and Doppler data with the Phobos 2 Lander on the surface of the Martian satellite Phobos is described. With the successful insertion on January 29, 1989 of Phobos 2 into Mars orbit, it is anticipated that the Lander will be placed on the surface of Phobos in April 1989. Depending on the longevity of the Lander, range and Doppler data for a period of from one to several years are expected. Because these data are of value in performing solar-system tests of general relativity, the current accuracy of the relevant relativity tests using Deep Space Network data from the Mariner-9 orbiter of Mars in 1971 and from the Viking Landers in 1976-1982 is reviewed. The expected improvement from data anticipated during the Phobos 2 Lander Mission is also discussed; most important will be an improved sensitivity to any time variation in the gravitational 'constant' as measured in atomic units.

  9. Correlated quadratures of resonance fluorescence and the generalized uncertainty relation

    NASA Technical Reports Server (NTRS)

    Arnoldus, Henk F.; George, Thomas F.; Gross, Rolf W. F.

    1994-01-01

    Resonance fluorescence from a two-state atom has been predicted to exhibit quadrature squeezing below the Heisenberg uncertainty limit, provided that the optical parameters (Rabi frequency, detuning, laser linewidth, etc.) are chosen carefully. When the correlation between two quadratures of the radiation field does not vanish, however, the Heisenberg limit for quantum fluctuations might be an unrealistic lower bound. A generalized uncertainty relation, due to Schroedinger, takes into account the possible correlation between the quadrature components of the radiation, and it suggests a modified definition of squeezing. We show that the coherence between the two levels of a laser-driven atom is responsible for the correlation between the quadrature components of the emitted fluorescence, and that the Schrodinger uncertainty limit increases monotonically with the coherence. On the other hand, the fluctuations in the quadrature field diminish with an increasing coherence, and can disappear completely when the coherence reaches 1/2, provided that certain phase relations hold.

  10. Cosmological Tests of General Relativity with tomographic surveys

    NASA Astrophysics Data System (ADS)

    Silvestri, Alessandra; Zhao, Gongbo; Pogosian, Levon; Zylberberg, Joel

    2010-02-01

    Future cosmological surveys, combining galaxy counts and weak lensing measurements, will map the evolution of matter perturbations and gravitational potentials from the matter dominated epoch until today. In addition to tightening the constraints on allowed expansion histories, the combination of these measurements will test the relationships between matter overdensities, local curvature, and the Newtonian potential. These relation- ships can be modi?ed in alternative theories of gravity and by exotic forms of Dark Energy. I will present a study of the potential of upcoming and future tomographic surveys, such as DES and LSST, with the aid of CMB and supernovae data, to detect departures from the growth of perturbations expected within General Relativity with a cosmological constant. )

  11. Three-state selective population of dressed states via generalized spectral phase-step modulation

    SciTech Connect

    Wollenhaupt, Matthias; Bayer, Tim; Baumert, Thomas; Vitanov, Nikolay V.

    2010-05-15

    We present a joint experimental and theoretical study of selective population of dressed states (SPODS) in a three-level system. Control is exerted by shaped intense femtosecond laser pulses generated by a generalized spectral phase-step modulation function. We show that both control parameters (i.e., the phase-step amplitude and position) can be used to switch population among each three dressed states with high selectivity. The dynamics of the system, and hence the resulting photoelectron signal is studied theoretically by analyzing the time evolution of the adiabatic dressed-state energies and populations.

  12. The Continuum of Psychotic Symptoms in the General Population: A Cross-national Study

    PubMed Central

    Nuevo, Roberto; Chatterji, Somnath; Verdes, Emese; Naidoo, Nirmala; Arango, Celso; Ayuso-Mateos, José Luis

    2012-01-01

    Objective: To identify the cross-national prevalence of psychotic symptoms in the general population and to analyze their impact on health status. Method: The sample was composed of 256 445 subjects (55.9% women), from nationally representative samples of 52 countries worldwide participating in the World Health Organization's World Health Survey. Standardized and weighted prevalence of psychotic symptoms were calculated in addition to the impact on health status as assessed by functioning in multiple domains. Results: Overall prevalences for specific symptoms ranged from 4.80% (SE = 0.14) for delusions of control to 8.37% (SE = 0.20) for delusions of reference and persecution. Prevalence figures varied greatly across countries. All symptoms of psychosis produced a significant decline in health status after controlling for potential confounders. There was a clear change in health impact between subjects not reporting any symptom and those reporting at least one symptom (effect size of 0.55). Conclusions: The prevalence of the presence of at least one psychotic symptom has a wide range worldwide varying as much as from 0.8% to 31.4%. Psychotic symptoms signal a problem of potential public health concern, independent of the presence of a full diagnosis of psychosis, as they are common and are related to a significant decrement in health status. The presence of at least one psychotic symptom is related to a significant poorer health status, with a regular linear decrement in health depending on the number of symptoms. PMID:20841326

  13. The relationship between chronotype and mood fluctuation in the general population.

    PubMed

    Jeong Jeong, Hee; Moon, Eunsoo; Min Park, Je; Dae Lee, Byung; Min Lee, Young; Choi, Yoonmi; In Chung, Young

    2015-10-30

    There is a lack of evidence for the relationship between chronotype and subthreshold mood fluctuation. The present study aims to investigate the relationship between chronotypes and mood fluctuation in the general population. Participants (n=302) who have had no experience of major mood episodes were included. The Korean version of the Composite Scale of Morningness (CSM) was used to classify participants according to three chronotypes. Mood fluctuation was measured using the Mood Disorder Questionnaire (MDQ) and the Bipolar Spectrum Diagnostic Scale (BSDS). Mean scores achieved by the three chronotype groups on the MDQ and the BSDS were compared. There were no significant differences in the frequency of positive responses on the MDQ for the three chronotype groups. However, there was a significant group difference in total BSDS scores. The eveningness group had significantly higher BSDS-D scores than did either the morningness or the intermediate group have. In addition, the eveningness group had significantly higher BSDS-M scores than the morningness group. After adjusting for age by the analysis of covariance (ANCOVA), there were still significant group differences in total BSDS scores. The present results suggest that eveningness may be more related to mood fluctuation than morningness. The eveningness may be an important factor related to soft bipolarity or mood fluctuation. PMID:26260565

  14. Integrated measures for rough sets based on general binary relations.

    PubMed

    Teng, Shuhua; Liao, Fan; He, Mi; Lu, Min; Nian, Yongjian

    2016-01-01

    Uncertainty measures are important for knowledge discovery and data mining. Rough set theory (RST) is an important tool for measuring and processing uncertain information. Although many RST-based methods for measuring system uncertainty have been investigated, the existing measures cannot adequately characterise the imprecision of a rough set. Moreover, these methods are suitable only for complete information systems, and it is difficult to generalise methods for complete information systems to incomplete information systems. To overcome these shortcomings, we present new uncertainty measures, integrated accuracy and integrated roughness, that are based on general binary relations, and we study important properties of these measures. A theoretical analysis and examples show that the proposed integrated measures are more precise than existing uncertainty measures, they are suitable for both complete and incomplete information systems, and they are logically consistent. Therefore, integrated accuracy and integrated roughness overcome the limitations of existing measures. This research not only develops the theory of uncertainty, it also expands the application domain of uncertainty measures and provides a theoretical basis for knowledge acquisition in information systems based on general binary relations. PMID:26900539

  15. A Conceptual Physics Course in General Relativity and Cosmology

    NASA Astrophysics Data System (ADS)

    Zeilik, Michael; Markus, M. Jennifer

    2005-04-01

    We have designed, implemented, assessed, and revised a new conceptual physics course at the University of New Mexico. Using the NRC/NAS report ``Connecting Quarks with the Cosmos'' (2003) as a guide, we pared down the 11 questions to six based on a student poll. The instructor (MZ) reconceptualized these six into a one- semester course focused on general relativity and cosmology, while taking into account known misconceptions research. The full implementation of an active- learning version took place in Spring 2003. The classes contained about 2/3 males and 1/3 females, about 60% ``freshmen.'' Some 50% took the course to meet a requirement. Students entered with a wide variety of math backgrounds, with the men reporting more advanced courses. We report on assessments to probe the success of the course based on our learning outcomes. In math and science aptitude, females and males ranked themselves the same at the start of the course; men felt more confident at the end. Using a conceptual diagnostic test as a pre- and post assessment, we found that males outscored the females pre- and post, but the normalized gains were the same. The normalized gains on Force Concept Inventory items was 0.2; for general relativity and cosmology ones, 0.5.

  16. Elliptical galaxies kinematics within general relativity with renormalization group effects

    SciTech Connect

    Rodrigues, Davi C.

    2012-09-01

    The renormalization group framework can be applied to Quantum Field Theory on curved space-time, but there is no proof whether the beta-function of the gravitational coupling indeed goes to zero in the far infrared or not. In a recent paper [1] we have shown that the amount of dark matter inside spiral galaxies may be negligible if a small running of the General Relativity coupling G is present (δG/G{sub 0}∼<10{sup −7} across a galaxy). Here we extend the proposed model to elliptical galaxies and present a detailed analysis on the modeling of NGC 4494 (an ordinary elliptical) and NGC 4374 (a giant elliptical). In order to compare our results to a well known alternative model to the standard dark matter picture, we also evaluate NGC 4374 with MOND. In this galaxy MOND leads to a significative discrepancy with the observed velocity dispersion curve and has a significative tendency towards tangential anisotropy. On the other hand, the approach based on the renormalization group and general relativity (RGGR) could be applied with good results to these elliptical galaxies and is compatible with lower mass-to-light ratios (of about the Kroupa IMF type)

  17. Atopic dermatitis, asthma and allergic rhinitis in general practice and the open population: a systematic review

    PubMed Central

    Pols, D. H. J.; Wartna, J. B.; Moed, H.; van Alphen, E. I.; Bohnen, A. M.; Bindels, P. J. E.

    2016-01-01

    Objective To examine whether significant differences exist between the self-reported prevalence of atopic disorders in the open population compared with physician diagnosed prevalence of atopic disorders in general practice. Methods Medline (OvidSP), PubMed Publisher, EMBASE, Google Scholar and the Cochrane Controlled Clinical Trials Register databases were systematically reviewed for articles providing data on the prevalence of asthma, allergic rhinitis and eczema in a GP setting. Studies were only included when they had a cross-sectional or cohort design and included more than 100 children (aged 0-18 years) in a general practice setting. All ISAAC studies (i.e. the open population) that geographically matched a study selected from the first search, were also included. A quality assessment was conducted. The primary outcome measures were prevalence of eczema, asthma and allergic rhinitis in children aged 0-18 years. Results The overall quality of the included studies was good. The annual and lifetime prevalences of the atopic disorders varied greatly in both general practice and the open population. On average, the prevalence of atopic disorders was higher in the open population. Conclusion There are significant differences between the self-reported prevalence of atopic disorders in the open population compared with physician diagnosed prevalence of atopic disorders in general practice. Data obtained in the open population cannot simply be extrapolated to the general practice setting. This should be taken into account when considering a research topic or requirements for policy development. GPs should be aware of the possible misclassification of allergic disorders in their practice. Key PointsEpidemiological data on atopic disorders in children can be obtained from various sources, each having its own advantages and limitations.On average, the prevalence of atopic disorders is higher in the open population.GPs should take into account the possible

  18. Altered self-perception in adult survivors treated for a CNS tumor in childhood or adolescence: population-based outcomes compared with the general population

    PubMed Central

    Hörnquist, Lina; Rickardsson, Jenny; Lannering, Birgitta; Gustafsson, Göran; Boman, Krister K.

    2015-01-01

    Background Survivors of pediatric CNS tumors are at risk for persistent tumor/treatment-related morbidity, physical disability and social consequences that may alter self-perception, vital for self-identity, mental health and quality of survival. We studied the long-term impact of childhood CNS tumors and their treatment on the self-perception of adult survivors and compared outcomes with those of the general population. Methods The cohort included 697 Swedish survivors diagnosed with a primary CNS tumor during 1982–2001. Comparison data were randomly collected from a stratified general population sample. Survivors and general population individuals were compared as regards self-perception in 5 domains: body image, sports/physical activities, peers, work, and family, and with a global self-esteem index. Within the survivor group, determinants of impact on self-perception were identified. Results The final analyzed sample included 528 survivors, 75.8% of the entire national cohort. The control sample consisted of 995, 41% of 2500 addressed. Survivors had significantly poorer self-perception outcomes in domains of peers, work, body image, and sports/physical activities, and in the global self-perception measure, compared with those of the general population (all P < .001). Within the survivor group, female gender and persistent visible physical sequelae predicted poorer outcomes in several of the studied domains. Tumor type and a history of cranial radiation therapy were associated with outcomes. Conclusion An altered self-perception is a potential late effect in adult survivors of pediatric CNS tumors. Self-perception and self-esteem are significant elements of identity, mental health and quality of survival. Therefore, care and psychosocial follow-up of survivors should include measures for identifying disturbances and for assessing the need for psychosocial intervention. PMID:25332406

  19. EQ-5D-5L in the General German Population: Comparison and Evaluation of Three Yearly Cross-Section Surveys

    PubMed Central

    Huber, Manuel B.; Reitmeir, Peter; Vogelmann, Martin; Leidl, Reiner

    2016-01-01

    Health-related quality of life (HRQoL) is a key measure for evaluating health status in populations. Using the recent EQ-5D-5L for measurement, this study analyzed quality of life results and their stability over consecutive population surveys. Three cross-section surveys for representative samples of the general German population from 2012, 2013, and 2014 were evaluated using the EQ-5D-5L descriptive system and valuation by the Visual Analog Scale (VAS). Aggregated sample size reached 6074. The dimension with the highest prevalence of problems was pain/discomfort (31.7%). Compared with 2012 (59.3%), the percentage of participants in the best health state increased slightly in 2013 (63.4%) and 2014 (62%). Over the 3-year period, diabetes and heart disease had the strongest negative influence on mean VAS result. The number of reported chronic diseases cumulatively reduced mean VAS. Extreme problems in one or more dimensions were stated by only 0.1%–0.2% of patients. Of the potential 247 health states with a problem score ≥20, only six were observed in the aggregated sample. HRQoL results were fairly stable over the 3 years, but the share of the population with no problems was not. Results from the aggregated sample may serve as updated reference values for the general German population. PMID:27007387

  20. Geospatial Modeling of Asthma Population in Relation to Air Pollution

    NASA Technical Reports Server (NTRS)

    Kethireddy, Swatantra R.; Tchounwou, Paul B.; Young, John H.; Luvall, Jeffrey C.; Alhamdan, Mohammad

    2013-01-01

    Current observations indicate that asthma is growing every year in the United States, specific reasons for this are not well understood. This study stems from an ongoing research effort to investigate the spatio-temporal behavior of asthma and its relatedness to air pollution. The association between environmental variables such as air quality and asthma related health issues over Mississippi State are investigated using Geographic Information Systems (GIS) tools and applications. Health data concerning asthma obtained from Mississippi State Department of Health (MSDH) for 9-year period of 2003-2011, and data of air pollutant concentrations (PM2.5) collected from USEPA web resources, and are analyzed geospatially to establish the impacts of air quality on human health specifically related to asthma. Disease mapping using geospatial techniques provides valuable insights into the spatial nature, variability, and association of asthma to air pollution. Asthma patient hospitalization data of Mississippi has been analyzed and mapped using quantitative Choropleth techniques in ArcGIS. Patients have been geocoded to their respective zip codes. Potential air pollutant sources of Interstate highways, Industries, and other land use data have been integrated in common geospatial platform to understand their adverse contribution on human health. Existing hospitals and emergency clinics are being injected into analysis to further understand their proximity and easy access to patient locations. At the current level of analysis and understanding, spatial distribution of Asthma is observed in the populations of Zip code regions in gulf coast, along the interstates of south, and in counties of Northeast Mississippi. It is also found that asthma is prevalent in most of the urban population. This GIS based project would be useful to make health risk assessment and provide information support to the administrators and decision makers for establishing satellite clinics in future.

  1. The Value of a College Degree for Foster Care Alumni: Comparisons with General Population Samples

    ERIC Educational Resources Information Center

    Salazar, Amy M.

    2013-01-01

    Higher education is associated with substantial adult life benefits, including higher income and improved quality of life, among others. The current study compared adult outcomes of 250 foster care alumni college graduates with two samples of general population graduates to explore the role higher education plays in these young adults' lives.…

  2. A New Screening Programme for Autism in a General Population of Swedish Toddlers

    ERIC Educational Resources Information Center

    Nygren, Gudrun; Sandberg, Eva; Gillstedt, Fredrik; Ekeroth, Gunnar; Arvidsson, Thomas; Gillberg, Christopher

    2012-01-01

    The evidence from early intervention studies of autism has emphasised the need for early diagnosis. Insight into the early presentation of autism is crucial for early recognition, and routine screening can optimise the possibility for early diagnosis. General population screening was conducted for 2.5-year-old children at child health centres in…

  3. The Relationship between General Population Suicide Rates and Educational Attainment: A Cross-National Study

    ERIC Educational Resources Information Center

    Shah, Ajit; Bhandarkar, Ritesh

    2009-01-01

    Suicides are associated with both high and low levels of intelligence and educational attainment in both individual-level and aggregate-level studies. A cross-national study examining the relationship between general population suicide rates ("y") and educational attainment ("x") was undertaken with the "a priori" hypothesis that the relationship…

  4. Comparing Psychiatric Service Use among Low-Income Women and Women in a General Household Population

    ERIC Educational Resources Information Center

    Rosen, Daniel; Warner, Lynn A.; Tolman, Richard M.

    2006-01-01

    This article examines the use of outpatient mental health services in a sample of low-income women (Mothers' Well-Being Study [MWS]) and compares the findings with a sample of similar-aged women in the general population (National Comorbidity Survey [NCS]). Overall, the prevalence of any 12-month mental health disorder was significantly greater…

  5. IDENTIFICATION OF POLYBROMINATED BIPHENYLS IN THE ADIPOSE TISSUES OF THE GENERAL POPULATION OF THE UNITED STATES

    EPA Science Inventory

    Hexabromobiphenyl has been identified by gas chromatography/mass spectrometry (GC/MS) in pooled extracts of adipose tissue samples collected from the general population of the conterminous United States. Mass spectra derived from tissue extracts subjected to gel permeation chroma...

  6. The Reliability and Validity of the Social Responsiveness Scale in a UK General Child Population

    ERIC Educational Resources Information Center

    Wigham, Sarah; McConachie, Helen; Tandos, Jonathan; Le Couteur, Ann S.

    2012-01-01

    This is the first UK study to report the reliability, validity, and factor structure of the Social Responsiveness Scale (SRS) in a general population sample. Parents of 500 children (aged 5-8 years) in North East England completed the SRS. Profiles of scores were similar to USA norms, and a single factor structure was identified. Good construct…

  7. Seroepidemiology of Toxoplasma gondii infection in general population in a Northern Mexican city

    Technology Transfer Automated Retrieval System (TEKTRAN)

    There is a lack of information about the seroepidemiology of T. gondii infection in the general population of Durango City, Mexico. Anti-T. gondii IgG and IgM antibodies were sought in 974 inhabitants in Durango City, Mexico using enzyme-linked immunoassays. In total, 59 (6.1%) of 974 participants (...

  8. Patients Taking Imatinib for CML Have Similar Risk of Death as General Population

    Cancer.gov

    In an international study, the risk of death for chronic myelogenous leukemia patients treated with imatinib (Gleevec) who had been in remission for at least 2 years was not different from that of the general population, according to an article in the March 21, 2011 issue of the Journal of the National Cancer Institute.

  9. RESIDUES AND METABOLITES OF SELECTED PERSISTENT HALOGENATED HYDROCARBONS IN BLOOD SPECIMENS FROM A GENERAL POPULATION SURVEY

    EPA Science Inventory

    The National Center for Health Statistics collaborated with the National Human Monitoring Program of the U.S. Environmental Protection Agency (EPA) in a four-year study to assess the exposure of the general population to selected pesticides through analysis of blood serum and uri...

  10. Prevalence of Contact Allergy to p-Phenylenediamine in the European General Population.

    PubMed

    Diepgen, Thomas L; Naldi, Luigi; Bruze, Magnus; Cazzaniga, Simone; Schuttelaar, Marie-Louise; Elsner, Peter; Goncalo, Margarida; Ofenloch, Robert; Svensson, Åke

    2016-02-01

    Population-based studies on contact allergy to p-phenylenediamine (PPD) are scarce. A cross-sectional study was performed to assess the prevalence of contact allergy to PPD and its risk factors in the general population of 5 European countries. A total of 10,425 subjects were interviewed, and a random sample (n = 2,739) was patch tested to PPD. Overall, 5,286 individuals (50.9%) reported having used hair colorants at least once in their lifetime (78% female, 20% male), and 35% had used hair colorants during the last 12 months. Hair colorant avoidance because of any skin problem during the lifetime was reported by 6%. Black henna tattoos had been used by 5.5% during their lifetime. The prevalence of PPD contact allergy was 0.8% (95% confidence interval 0.6-1.0%), with no statistically significant association with gender or hair dye use. The prevalence of PPD in black henna tattoo users was 3.2% versus 0.6% in nonusers (P < 0.001). A clinically relevant positive patch test reaction to PPD related to hair coloring products was found in 0.1% (95% confidence interval 0.0-0.2%). A significant association with PPD contact allergy was observed for subjects who had black henna tattoos in their lifetime, with an age- and gender-adjusted odds ratio of 9.33 (95% confidence interval 3.45-25.26, P < 0.001). Black henna tattoos are an important risk factor for PPD contact allergy. PMID:26802237

  11. A Generalized Brownian Motion Model for Turbulent Relative Particle Dispersion

    NASA Astrophysics Data System (ADS)

    Shivamoggi, Bhimsen

    2015-11-01

    A generalized Brownian motion model has been applied to the turbulent relative particle dispersion problem (Shivamoggi). The fluctuating pressure forces acting on a fluid particle are taken to follow an Uhlenbeck-Ornstein process while it appears plausible to take their correlation time to have a power-law dependence on the flow Reynolds number Re. This ansatz provides an insight into the result that the Richardson-Obukhov scaling holds only in the infinite-Re limit and disappears otherwise. It provides a determination of the Richardson-Obukhov constant g as a function of Re, with an asymptotic constant value in the infinite-Re limit. This ansatz is further shown to be in quantitative agreement, in the small-Re limit, with the Batchelor-Townsend ansatz for the rate of change of the mean square interparticle separation in 3D FDT. My thanks to The Netherlands Organization for Scientific Research for Support.

  12. CPT symmetry and antimatter gravity in general relativity

    NASA Astrophysics Data System (ADS)

    Villata, M.

    2011-04-01

    The gravitational behavior of antimatter is still unknown. While we may be confident that antimatter is self-attractive, the interaction between matter and antimatter might be either attractive or repulsive. We investigate this issue on theoretical grounds. Starting from the CPT invariance of physical laws, we transform matter into antimatter in the equations of both electrodynamics and gravitation. In the former case, the result is the well-known change of sign of the electric charge. In the latter, we find that the gravitational interaction between matter and antimatter is a mutual repulsion, i.e. antigravity appears as a prediction of general relativity when CPT is applied. This result supports cosmological models attempting to explain the Universe accelerated expansion in terms of a matter-antimatter repulsive interaction.

  13. General relativity as an attractor for scalar-torsion cosmology

    NASA Astrophysics Data System (ADS)

    Järv, Laur; Toporensky, Alexey

    2016-01-01

    We study flat Friedmann-Lemaître-Robertson-Walker cosmological models for a scalar field coupled nonminimally to teleparallel gravity with generic coupling and potential functions. The goal in this paper is to determine the conditions under which cosmological evolution tends to the limit where the variation of the gravitational "constant" ceases and the system evolves close to general relativity (GR). These conditions can be read off from the approximate analytical solutions describing the process in matter and potential domination eras. Only those models where the GR limit exists and is an attractor can be considered viable. We expect the results to hold in the original "pure tetrad" formulation as well as in the recently suggested covariant formulation of the teleparallel theory. In the former case the GR attractor simultaneously provides a mechanism for how cosmological evolution suppresses the problematic degrees of freedom stemming from the lack of local Lorentz invariance.

  14. Proper Time Dynamics in General Relativity and Conformal Unified Theory

    NASA Astrophysics Data System (ADS)

    Gyngazov, L. N.; Pawlowski, M.; Pervushin, V. N.; Smirichinski, V. I.

    1998-12-01

    The paper is devoted to the description a measurable time-interval ("proper time") in the Hamiltonian version of general relativity with the Dirac-ADM metric. To separate the dynamical parameter of evolution from the space metric we use the Lichnerowicz conformally invariant variables. In terms of these variables GR is equivalent to the conformally invariant Penrose-Chernikov-Tagirov theory of a scalar field the role of which is played by the scale factor multiplied by the Planck constant. Identification of this scalar field with the modulus of the Higgs field in the standard model of electroweak and strong interactions allows us to formulate an example of conformally invariant unified theory where the vacuum averaging of the scalar field is determined by cosmological integrals of motion of the evolution of the universe.

  15. Collapse of magnetized hypermassive neutron stars in general relativity.

    PubMed

    Duez, Matthew D; Liu, Yuk Tung; Shapiro, Stuart L; Shibata, Masaru; Stephens, Branson C

    2006-01-27

    Hypermassive neutron stars (HMNSs)--equilibrium configurations supported against collapse by rapid differential rotation--are possible transient remnants of binary neutron-star mergers. Using newly developed codes for magnetohydrodynamic simulations in dynamical spacetimes, we are able to track the evolution of a magnetized HMNS in full general relativity for the first time. We find that secular angular momentum transport due to magnetic braking and the magnetorotational instability results in the collapse of an HMNS to a rotating black hole, accompanied by a gravitational wave burst. The nascent black hole is surrounded by a hot, massive torus undergoing quasistationary accretion and a collimated magnetic field. This scenario suggests that HMNS collapse is a possible candidate for the central engine of short gamma-ray bursts. PMID:16486677

  16. The Gravity Probe B test of general relativity

    NASA Astrophysics Data System (ADS)

    Everitt, C. W. F.; Muhlfelder, B.; DeBra, D. B.; Parkinson, B. W.; Turneaure, J. P.; Silbergleit, A. S.; Acworth, E. B.; Adams, M.; Adler, R.; Bencze, W. J.; Berberian, J. E.; Bernier, R. J.; Bower, K. A.; Brumley, R. W.; Buchman, S.; Burns, K.; Clarke, B.; Conklin, J. W.; Eglington, M. L.; Green, G.; Gutt, G.; Gwo, D. H.; Hanuschak, G.; He, X.; Heifetz, M. I.; Hipkins, D. N.; Holmes, T. J.; Kahn, R. A.; Keiser, G. M.; Kozaczuk, J. A.; Langenstein, T.; Li, J.; Lipa, J. A.; Lockhart, J. M.; Luo, M.; Mandel, I.; Marcelja, F.; Mester, J. C.; Ndili, A.; Ohshima, Y.; Overduin, J.; Salomon, M.; Santiago, D. I.; Shestople, P.; Solomonik, V. G.; Stahl, K.; Taber, M.; Van Patten, R. A.; Wang, S.; Wade, J. R.; Worden, P. W., Jr.; Bartel, N.; Herman, L.; Lebach, D. E.; Ratner, M.; Ransom, R. R.; Shapiro, I. I.; Small, H.; Stroozas, B.; Geveden, R.; Goebel, J. H.; Horack, J.; Kolodziejczak, J.; Lyons, A. J.; Olivier, J.; Peters, P.; Smith, M.; Till, W.; Wooten, L.; Reeve, W.; Anderson, M.; Bennett, N. R.; Burns, K.; Dougherty, H.; Dulgov, P.; Frank, D.; Huff, L. W.; Katz, R.; Kirschenbaum, J.; Mason, G.; Murray, D.; Parmley, R.; Ratner, M. I.; Reynolds, G.; Rittmuller, P.; Schweiger, P. F.; Shehata, S.; Triebes, K.; VandenBeukel, J.; Vassar, R.; Al-Saud, T.; Al-Jadaan, A.; Al-Jibreen, H.; Al-Meshari, M.; Al-Suwaidan, B.

    2015-11-01

    The Gravity Probe B mission provided two new quantitative tests of Einstein’s theory of gravity, general relativity (GR), by cryogenic gyroscopes in Earth’s orbit. Data from four gyroscopes gave a geodetic drift-rate of -6601.8 ± 18.3 marc-s yr-1 and a frame-dragging of -37.2 ± 7.2 marc-s yr-1, to be compared with GR predictions of -6606.1 and -39.2 marc-s yr-1 (1 marc-s = 4.848 × 10-9 radians). The present paper introduces the science, engineering, data analysis, and heritage of Gravity Probe B, detailed in the accompanying 20 CQG papers.

  17. Remarks on the consistency of minimal deviations from general relativity

    SciTech Connect

    Pons, Josep M.; Talavera, Pere

    2010-08-15

    We study the consequences of some possible modifications of the phase space structure of general relativity imposed by breaking, in the simplest manner, the full diffeomorphism invariance but retaining the time foliation preserving diffeomorphisms. We examine the different sectors in phase space that satisfy the new structure of constraints. For some sectors we find an infinite tower of constraints. In spite of that, we also show that these sectors allow for solutions, among them some well-known families of black hole and cosmologies which fulfill all the constraints. We raise some physical concerns on the consequences of an absolute Galilean time, on the thermodynamical pathologies of such models, and on their unusual vacuum structure.

  18. Ambiguous tests of general relativity on cosmological scales

    SciTech Connect

    Zuntz, Joe; Baker, Tessa; Ferreira, Pedro G.; Skordis, Constantinos E-mail: tessa.baker@astro.ox.ac.uk E-mail: skordis@nottingham.ox.ac.uk

    2012-06-01

    There are a number of approaches to testing General Relativity (GR) on linear scales using parameterized frameworks for modifying cosmological perturbation theory. It is sometimes assumed that the details of any given parameterization are unimportant if one uses it as a diagnostic for deviations from GR. In this brief report we argue that this is not necessarily so. First we show that adopting alternative combinations of modifications to the field equations significantly changes the constraints that one obtains. In addition, we show that using a parameterization with insufficient freedom significantly tightens the apparent theoretical constraints. Fundamentally we argue that it is almost never appropriate to consider modifications to the perturbed Einstein equations as being constraints on the effective gravitational constant, for example, in the same sense that solar system constraints are. The only consistent modifications are either those that grant near-total freedom, as in decomposition methods, or ones which map directly to a particular part of theory space.

  19. Generalized Einstein relation in tilted periodic potential: a semiclassical approach.

    PubMed

    Shit, Anindita; Chattopadhyay, Sudip; Banik, Suman Kumar; Chaudhuri, Jyotipratim Ray

    2010-06-17

    This paper concerns the investigation of the quantum motion of a system in a dissipative Ohmic heat bath in the presence of an external field using the traditional system-reservoir model. Using physically motivated initial conditions, we then obtain the c-number of the generalized quantum Langevin equation by which we calculate the quantum correction terms using a perturbation technique. As a result of this, one can apply a classical differential equation-based approach to consider quantum diffusion in a tilted periodic potential, and thus our approach is easy to use. We use our expression to calculate the Einstein relation for the quantum Brownian particle in a ratchet-type potential in a very simple closed analytical form using a suitable and convenient approximation. It is found that the diffusion rate is independent of the detailed form of the potential both in quantum and classical regimes, which is the main essence of this work. PMID:20481540

  20. Assessing the Representativeness of Population-Sampled Health Surveys Through Linkage to Administrative Data on Alcohol-Related Outcomes

    PubMed Central

    Gorman, Emma; Leyland, Alastair H.; McCartney, Gerry; White, Ian R.; Katikireddi, Srinivasa Vittal; Rutherford, Lisa; Graham, Lesley; Gray, Linsay

    2014-01-01

    Health surveys are an important resource for monitoring population health, but selective nonresponse may impede valid inference. This study aimed to assess nonresponse bias in a population-sampled health survey in Scotland, with a focus on alcohol-related outcomes. Nonresponse bias was assessed by examining whether rates of alcohol-related harm (i.e., hospitalization or death) and all-cause mortality among respondents to the Scottish Health Surveys (from 1995 to 2010) were equivalent to those in the general population, and whether the extent of any bias varied according to sociodemographic attributes or over time. Data from consenting respondents (aged 20–64 years) to 6 Scottish Health Surveys were confidentially linked to death and hospitalization records and compared with general population counterparts. Directly age-standardized incidence rates of alcohol-related harm and all-cause mortality were lower among Scottish Health Survey respondents compared with the general population. For all years combined, the survey-to-population rate ratios were 0.69 (95% confidence interval: 0.61, 0.76) for the incidence of alcohol-related harm and 0.89 (95% confidence interval: 0.83, 0.96) for all-cause mortality. Bias was more pronounced among persons residing in more deprived areas; limited evidence was found for regional or temporal variation. This suggests that corresponding underestimation of population rates of alcohol consumption is likely to be socially patterned. PMID:25227767

  1. Fatigue in the general Korean population: application and normative data of the Brief Fatigue Inventory.

    PubMed

    Yun, Young Ho; Lee, Myung Kyung; Chun, Han Na; Lee, Young Mi; Park, Sang Min; Mendoza, Tito R; Wang, Xin Shelley; Cleeland, Charles S

    2008-09-01

    The purpose of this study was to provide normative data for the Brief Fatigue Inventory (BFI) in the general Korean population so that the results for the general population could be compared with those for patients. We constructed a questionnaire that included the BFI and items on demographic characteristics and conducted a population-based, cross-sectional survey in 1,000 individuals. We used multivariate logistic analysis to investigate factors associated with "usual" and "worst" fatigue. The internal consistency was very high (Cronbach's alpha=0.96) and construct validity was confirmed by factor analysis. All patients had a mean+/-SD BFI score of 4.33+/-2.48 for "worst" fatigue and of 4.07+/-2.27 for "usual" fatigue, and the global BFI score was 3.44+/-2.05. The prevalence of each moderate-to-severe fatigue type was similar in severity of fatigue, with 55.2% in "usual" fatigue, and 57.3% in "worst" fatigue. Among the types of fatigue, the prevalence of severe fatigue was lowest for "usual" fatigue (16.5%). In multivariate analyses, the group aged 40-59 years had greater levels of "usual" and "worst" fatigue compared with the group aged 20-29 years. Poor general health and the presence of comorbidities were also associated with increased "usual" and "worst" fatigue. Regular physical activity was associated with reduced levels of "worst" fatigue. The normal values of BFI with proper psychometric properties may help us to better understand the correlates of fatigue in the general population and patients. Our findings indicate that comorbidities should be considered when comparing fatigue data from the general population with data from patients. PMID:18411013

  2. Sexual assault while too intoxicated to resist: a general population study of Norwegian teenage girls

    PubMed Central

    2014-01-01

    Background Underage drinking is widespread, but studies on alcohol-related sexual victimization among teenage girls are almost non-existent. Research on individual correlates and risk factors of sexual victimization more generally is also meager. This study focuses on sexual assault while incapacitated due to drunkenness among 15–18 year-old girls and examines how age, drinking behavior, impulsivity and involvement in norm-violating activities are associated with such victimization experiences. Methods Data stemmed from a school survey (response rate: 85%) in 16 Norwegian municipalities. Almost all analyses were restricted to girls who had been intoxicated in the past year (n = 2701). In addition to bivariate associations, adjusted odds ratios and relative risks of incapacitated sexual assault (ISA) were estimated. Further, population-attributable fractions were calculated to explore how the prevalence of ISA victimization was likely to be affected if effective preventive measures were targeted solely at high-risk groups. Results The majority of the girls (71%) had been intoxicated in the past year, of which 7% had experienced ISA victimization in the same period. The proportion of victims decreased by age within the group that had been intoxicated, reflecting that the youngest girls were more likely to get severely drunk. Impulsivity and involvement in norm-violating behaviors were identified as potential risk factors, but the population-attributable fractions indicated that the groups with the highest risk of ISA victimization accounted for only a minority of all the cases of such victimization. Conclusion Sexual assault against teenage girls who are too drunk to resist seems to be prevalent in Norway – notably among the youngest girls who engage in heavy episodic drinking. This study also suggests that one should reconsider the notion that no individual attributes are related to females’ sexual assault victimization. It also indicates that a high risk

  3. Fluctuation Relations of Fitness and Information in Population Dynamics

    NASA Astrophysics Data System (ADS)

    Kobayashi, Tetsuya J.; Sughiyama, Yuki

    2015-12-01

    Phenotype switching with and without sensing environment is a common strategy of organisms to survive in a fluctuating environment. Understanding the evolutionary advantages of switching and sensing requires a quantitative evaluation of their fitness gain and its fluctuation together with the conditions for the switching and sensing strategies being adapted to a given environment. In this work, by using a pathwise formulation of the population dynamics, we show that the optimal switching strategy is characterized by a consistency condition for time-forward and backward path probabilities. The formulation also clarifies the underlying information-theoretic aspect of selection as a passive information compression. The loss of fitness by a suboptimal strategy is also shown to satisfy a fluctuation relation, which provides us with the information on how environmental fluctuation impacts the advantages of the optimal strategy. These results are naturally extended to the situation that organisms can use an environmental signal by actively sensing the environment. The fluctuation relations of the fitness gain by sensing are derived in which the multivariate mutual information among the phenotype, the environment, and the signal plays the role to quantify the relevant information in the signal for the fitness gain.

  4. Axis II disorders and cigarette smoking among adults from the general population.

    PubMed

    Becoña, Elisardo; Fernández del Río, Elena; López-Durán, Ana; Piñeiro, Bárbara; Martínez, Úrsula

    2013-06-01

    The present study examined whether personality disorders (PDs) are associated with cigarette smoking, and the possible influence of nicotine dependence, sociodemographic variables, and the presence of any lifetime Axis I mental disorder in these relationships. The sample was made up of 1,081 adult participants from the Spanish general population and was stratified by smoking status (519 smokers and 562 nonsmokers). PDs were assessed by means of the International Personality Disorder Examination Questionnaire, Module DSM-IV. Results indicated that participants with a paranoid, a narcissistic, a borderline, an antisocial, or an obsessive-compulsive PD had a higher probability for being smokers and for being nicotine-dependent. The only exception was the schizoid PD, because participants with this Axis II disorder had a lower probability for being nicotine-dependent smokers. The association between PDs and smoking was maintained even after adjusting for all covariates. Findings are discussed in relation to the influence of Axis II disorders on smoking cessation interventions. PMID:22928853

  5. The Youth Psychopathic Traits Inventory-Short Version in a general population sample of emerging adults.

    PubMed

    Colins, Olivier F; Andershed, Henrik

    2016-05-01

    Prior studies with children and adolescents have shown that Youth Psychopathic Traits Inventory-Short Version (YPI-S) scores are internally consistent and manifest expected relations with external variables of interest. In the present study, the factor structure and the internal consistency of YPI-S scores, and the convergent validity of the interpretation of YPI-S scores were tested in a sample of 2,500 emerging adults from the general population in Sweden (aged 20-24 years; 52.6% women). Results of exploratory and confirmatory factor analyses support a 3-factor structure among both men and women that is similar to prior YPI-S studies conducted with children and adolescents. The YPI-S total score and the 3 factor scores were internally consistent. Correlations with external variables, including aggression and delinquency, support the convergent validity of the interpretation of YPI-S scores. Finally, the strength of these zero-order and partial correlations, overall, was not significantly different across gender. In conclusion, this study provides initial evidence that the YPI-S may hold promise as a brief and time-effective self-report tool for assessing psychopathic traits in emerging adults. The present findings also suggest that the YPI-S performs in a consistent manner across gender. Recommendations for future research with the YPI-S are discussed. (PsycINFO Database Record PMID:26302107

  6. General population job exposure matrix applied to a pooled study of prevalent carpal tunnel syndrome.

    PubMed

    Dale, Ann Marie; Zeringue, Angelique; Harris-Adamson, Carisa; Rempel, David; Bao, Stephen; Thiese, Matthew S; Merlino, Linda; Burt, Susan; Kapellusch, Jay; Garg, Arun; Gerr, Fred; Hegmann, Kurt T; Eisen, Ellen A; Evanoff, Bradley

    2015-03-15

    A job exposure matrix may be useful for the study of biomechanical workplace risk factors when individual-level exposure data are unavailable. We used job title-based exposure data from a public data source to construct a job exposure matrix and test exposure-response relationships with prevalent carpal tunnel syndrome (CTS). Exposures of repetitive motion and force from the Occupational Information Network were assigned to 3,452 active workers from several industries, enrolled between 2001 and 2008 from 6 studies. Repetitive motion and force exposures were combined into high/high, high/low, and low/low exposure groupings in each of 4 multivariable logistic regression models, adjusted for personal factors. Although force measures alone were not independent predictors of CTS in these data, strong associations between combined physical exposures of force and repetition and CTS were observed in all models. Consistent with previous literature, this report shows that workers with high force/high repetition jobs had the highest prevalence of CTS (odds ratio = 2.14-2.95) followed by intermediate values (odds ratio = 1.09-2.27) in mixed exposed jobs relative to the lowest exposed workers. This study supports the use of a general population job exposure matrix to estimate workplace physical exposures in epidemiologic studies of musculoskeletal disorders when measures of individual exposures are unavailable. PMID:25700886

  7. General Population Job Exposure Matrix Applied to a Pooled Study of Prevalent Carpal Tunnel Syndrome

    PubMed Central

    Dale, Ann Marie; Zeringue, Angelique; Harris-Adamson, Carisa; Rempel, David; Bao, Stephen; Thiese, Matthew S.; Merlino, Linda; Burt, Susan; Kapellusch, Jay; Garg, Arun; Gerr, Fred; Hegmann, Kurt T.; Eisen, Ellen A.; Evanoff, Bradley

    2015-01-01

    A job exposure matrix may be useful for the study of biomechanical workplace risk factors when individual-level exposure data are unavailable. We used job title–based exposure data from a public data source to construct a job exposure matrix and test exposure-response relationships with prevalent carpal tunnel syndrome (CTS). Exposures of repetitive motion and force from the Occupational Information Network were assigned to 3,452 active workers from several industries, enrolled between 2001 and 2008 from 6 studies. Repetitive motion and force exposures were combined into high/high, high/low, and low/low exposure groupings in each of 4 multivariable logistic regression models, adjusted for personal factors. Although force measures alone were not independent predictors of CTS in these data, strong associations between combined physical exposures of force and repetition and CTS were observed in all models. Consistent with previous literature, this report shows that workers with high force/high repetition jobs had the highest prevalence of CTS (odds ratio = 2.14–2.95) followed by intermediate values (odds ratio = 1.09–2.27) in mixed exposed jobs relative to the lowest exposed workers. This study supports the use of a general population job exposure matrix to estimate workplace physical exposures in epidemiologic studies of musculoskeletal disorders when measures of individual exposures are unavailable. PMID:25700886

  8. Rates and characteristics of sleep paralysis in the general population of Denmark and Egypt.

    PubMed

    Jalal, Baland; Hinton, Devon E

    2013-09-01

    In the current research we report data from two studies that examined rates and characteristics of sleep paralysis (SP) in the general population of Denmark and Egypt. In Study I, individuals from Denmark and Egypt did not differ in age whereas there were more males in the Egyptian sample (47 vs. 64 %); in Study II, individuals from Denmark and Egypt were comparable in terms of age and gender distribution. In Study I we found that significantly fewer individuals had experienced SP in Denmark [25 % (56/223)] than in Egypt [44 % (207/470)] p < .001. In Study II we found that individuals who had experienced at least one lifetime episode of SP from Denmark (n = 58) as compared to those from Egypt (n = 143) reported significantly fewer SP episodes in a lifetime relative to SP experiencers from Egypt (M = 6.0 vs. M = 19.4, p < .001). SP in the Egyptian sample was characterized by high rates of SP (as compared to in Denmark), frequent occurrences (three times that in the Denmark sample), prolonged immobility during SP, and great fear of dying from the experience. In addition, in Egypt, believing SP to be precipitated by the supernatural was associated with fear of the experience and longer SP immobility. Findings are discussed in the context of cultural elaboration and salience theories of SP. PMID:23884906

  9. Untreated hypertension in the UK household population - Who are missed by the general health checks?

    PubMed

    Petersen, Jakob; Benzeval, Michaela

    2016-12-01

    Hypertension is an age-related, long-term condition and a leading risk factor for premature death and disability worldwide. Due to its asymptomatic nature it can often be left undiagnosed. Long-term treatment is available, but blood pressure can also be reduced through health behaviour changes in weight control, smoking cessation, higher physical activity levels, reduced salt and alcohol intake, and healthful diets if discovered early. This paper investigates the prevalence and characteristics of those with untreated (compared to treated) hypertension who did not have a history of cardiovascular disease (CVD); a group who is in effect missed by general health checks. Untreated hypertension was studied in 8933 individuals aged 40-74 years representative of the UK household population, who were interviewed and underwent a physical health examination in their home, 2010-2012. The prevalence of untreated hypertension without a history of CVD was 7% for men, 2% for women, and 5% overall. Untreated hypertension was particularly high among the 55-64 year age group. Age and sex-adjusted analyses found strong positive associations with male gender, smoking, self-reported good-excellent health, full fat dairy preference, white bread preference, higher alcohol consumption, and living alone. Strong negative associations were found for possessing 5 + prescription drugs, statins or antiplatelets, being diagnosed with diabetes or possessing antidiabetics, and long-term limiting illness status. Notably, many reported their health as good to excellent. A fact which emphasises the importance of motivating individuals to take part in the general health checks for an asymptomatic condition such as hypertension. PMID:27413665

  10. A Search for Extreme Horizontal Branch Stars in the General Field Population

    NASA Astrophysics Data System (ADS)

    Walker, Douglas; Albrow, Michael

    2014-05-01

    The study of pulsating Extreme Horizontal Branch (EHB) stars in globular clusters is a new field of stellar research. The initial discovery of three rapidly pulsating EHB stars in omega Centauri was announced at the Fourth Meeting on Hot Subdwarfs and Related Objects held in Shanghai in July 2009. A fourth sdB pulsator was discovered in the remaining photometry data soon afterwards; all discovered in data obtained by the New Technology Telescope. In March 2013, the Space Telescope Imaging Spectrograph (STIS) was utilized on five consecutive orbits to obtain far-UV imagery of NGC 2808's core revealing six sdB pulsators with periods 85 to 149 seconds and UV amplitudes from 2.0 to 6.8%. To date (April, 2014), these 10 EHB pulsators in omega Centauri and NGC 2808 form a unique class of EHB variable closely clustered around Teff ~50,000 K. Based on a lack of information, a more in-depth observational search is needed for sdB variables both in the general field population and other clusters focusing particularly on He-poor sdB stars around and above Teff ~50,000 K. This talk describes an initial candidate search for EHB rapidly pulsating sdB stars in the general galactic field population. The search was conducted with the 1-m McLellan telescope at the Mt John University Observatory (MJUO), at Lake Tekapo, New Zealand. Observations were conducted utilizing a special high speed f/8 frametransfer camera called the Puoko-nui. The candidate set of stars were taken from the Edinburgh-Cape Blue Object Survey based on the selection criteria of a (B-V) value of -0.32 to -0.36 corresponding to the desired temperature range Teff ranging from 40,000 to 64,000 K. The objective of this search was to determine whether smaller size telescopes could identify promising sets of candidate sdB pulsators which could be followed up with larger professional systems.

  11. Origins and development of the Cauchy problem in general relativity

    NASA Astrophysics Data System (ADS)

    Ringström, Hans

    2015-06-01

    The seminal work of Yvonne Choquet-Bruhat published in 1952 demonstrates that it is possible to formulate Einstein's equations as an initial value problem. The purpose of this article is to describe the background to and impact of this achievement, as well as the result itself. In some respects, the idea of viewing the field equations of general relativity as a system of evolution equations goes back to Einstein himself; in an argument justifying that gravitational waves propagate at the speed of light, Einstein used a special choice of coordinates to derive a system of wave equations for the linear perturbations on a Minkowski background. Over the following decades, Hilbert, de Donder, Lanczos, Darmois and many others worked to put Einstein's ideas on a more solid footing. In fact, the issue of local uniqueness (giving a rigorous justification for the statement that the speed of propagation of the gravitational field is bounded by that of light) was already settled in the 1930s by the work of Stellmacher. However, the first person to demonstrate both local existence and uniqueness in a setting in which the notion of finite speed of propagation makes sense was Yvonne Choquet-Bruhat. In this sense, her work lays the foundation for the formulation of Einstein's equations as an initial value problem. Following a description of the results of Choquet-Bruhat, we discuss the development of three research topics that have their origin in her work. The first one is local existence. One reason for addressing it is that it is at the heart of the original paper. Moreover, it is still an active and important research field, connected to the problem of characterizing the asymptotic behaviour of solutions that blow up in finite time. As a second topic, we turn to the questions of global uniqueness and strong cosmic censorship. These questions are of fundamental importance to anyone interested in justifying that the Cauchy problem makes sense globally. They are also closely

  12. Prevalence of insomnia-related symptoms continues to increase in the Finnish working-age population.

    PubMed

    Kronholm, Erkki; Partonen, Timo; Härmä, Mikko; Hublin, Christer; Lallukka, Tea; Peltonen, Markku; Laatikainen, Tiina

    2016-08-01

    In 2008, we published epidemiological data from 1972 to 2005 that suggested an increase in insomnia-related symptoms among the working-age population. The results were based on the National FINRISK (FR) Study samples of the Finnish adult population aged 25-64, and on the Finnish Quality of Work Life Surveys (FQWLS), carried out among Finnish salary earners. Both of these ongoing studies have since provided two new estimates of insomnia-related symptoms. Chronic insomnia-related symptoms were 9.0% (95% CI 8.3-9.7), 9.6% (95% CI 8.8-10.4) in FR 2007 and 2012, respectively; and 9.1% (95% CI 8.3-10.0), 9.2% (95% CI 8.4-10.1) in FQWLS 2008 and 2013, respectively. Occasional insomnia-related symptoms were 45.3% (95% CI 44.1-46.6), 42.5% (95% CI 41.1-43.9) in FR 2007 and 2012, respectively; and 40.3% (95% CI 38.8-41.7), 44.8% (95% CI 41.1-43.9) in FQWLS 2008 and 2013, respectively. The new estimates further strengthen the interpretation of the ongoing increase in occasional insomnia-related symptoms among the Finnish general adult population. The increase in occasional symptoms was most prominent among employees. However, chronic insomnia symptoms showed no further increase. PMID:26868677

  13. Cosmological General Relativity with Scale Factor and Dark Energy

    NASA Astrophysics Data System (ADS)

    Oliveira, Firmin J.

    2014-11-01

    In this paper the four-dimensional (4-D) space-velocity Cosmological General Relativity of Carmeli is developed by a general solution of the Einstein field equations. The Tolman metric is applied in the form where g μν is the metric tensor. We use comoving coordinates x α = ( x 0, x 1, x 2, x 3) = ( τv, r, θ, ϕ), where τ is the Hubble-Carmeli time constant, v is the universe expansion velocity and r, θ and ϕ are the spatial coordinates. We assume that μ and R are each functions of the coordinates τv and r. The vacuum mass density ρ Λ is defined in terms of a cosmological constant Λ, where the Carmeli gravitational coupling constant κ = 8 πG/ c 2 τ 2, where c is the speed of light in vacuum. This allows the definitions of the effective mass density and effective pressure where ρ is the mass density and p is the pressure. Then the energy-momentum tensor where u μ = (1,0,0,0) is the 4-velocity. The Einstein field equations are taken in the form where R μν is the Ricci tensor, κ = 8 πG/ c 2 τ 2 is Carmeli's gravitation constant, where G is Newton's constant and the trace T = g αβ T αβ . By solving the field equations (6) a space-velocity cosmology is obtained analogous to the Friedmann-Lemaître-Robertson-Walker space-time cosmology. We choose an equation of state such that with an evolving state parameter where R v = R v ( v) is the scale factor and w 0 and w a are constants. Carmeli's 4-D space-velocity cosmology is derived as a special case.

  14. Mortality Among Adults With Intellectual Disability in England: Comparisons With the General Population

    PubMed Central

    Hosking, Fay J.; Shah, Sunil M.; Harris, Tess; DeWilde, Stephen; Beighton, Carole; Cook, Derek G.

    2016-01-01

    Objectives. To describe mortality among adults with intellectual disability in England in comparison with the general population. Methods. We conducted a cohort study from 2009 to 2013 using data from 343 general practices. Adults with intellectual disability (n = 16 666; 656 deaths) were compared with age-, gender-, and practice-matched controls (n = 113 562; 1358 deaths). Results. Adults with intellectual disability had higher mortality rates than controls (hazard ratio [HR] = 3.6; 95% confidence interval [CI] = 3.3, 3.9). This risk remained high after adjustment for comorbidity, smoking, and deprivation (HR = 3.1; 95% CI = 2.7, 3.4); it was even higher among adults with intellectual disability and Down syndrome or epilepsy. A total of 37.0% of all deaths among adults with intellectual disability were classified as being amenable to health care intervention, compared with 22.5% in the general population (HR = 5.9; 95% CI = 5.1, 6.8). Conclusions. Mortality among adults with intellectual disability is markedly elevated in comparison with the general population, with more than a third of deaths potentially amenable to health care interventions. This mortality disparity suggests the need to improve access to, and quality of, health care among people with intellectual disability. PMID:27310347

  15. Sleep Difficulties and Insomnia Symptoms in Norwegian Musicians Compared to the General Population and Workforce.

    PubMed

    Vaag, Jonas; Saksvik-Lehouillier, Ingvild; Bjørngaard, Johan Håkon; Bjerkeset, Ottar

    2016-01-01

    Sleep problems are reported as common among performing artists and musicians. However, epidemiological research comparing musicians to different groups of the general population is lacking. For this study, 4,168 members of the Norwegian Musician's Union were invited to an online survey regarding work and health. Of the 2,121 (51%) respondents, 1,607 were active performing musicians. We measured prevalence of insomnia symptoms using the Bergen Insomnia Scale (BIS), and compared this sample to a representative sample of the general Norwegian population (n = 2,645). Overall, musicians had higher prevalence of insomnia symptoms compared to the general population (Prevalence Difference 6.9, 95% Confidence Interval 3.9-10.0). Item response analysis showed that this difference was mainly explained by nonrestorative sleep and dissatisfaction with sleep among musicians. An additional analysis, comparing musicians to the general Norwegian workforce (n = 8,518) on sleep difficulties, confirmed this tendency (Prevalence Difference 6.2, 95% Confidence Interval 4.3-8.1). Musicians performing classical, contemporary, rock, and country music reported the highest prevalence of insomnia, and these genres might be of special interest when developing preventative measures, treatment strategies, and further research on sleep difficulties among musicians. PMID:26337077

  16. GENERAL: A Possible Population-Driven Phase Transition in Cicada Chorus

    NASA Astrophysics Data System (ADS)

    Gu, Si-Yuan; Jin, Yu-Liang; Zhao, Xiao-Xue; Huang, Ji-Ping

    2009-06-01

    We investigate the collective synchronization of cicada chirping. Using both experimental and phenomenological numerical techniques, here we show that the onset of a periodic two-state acoustic synchronous behavior in cicada chorus depends on a critical size of population Nc = 21, above which a typical chorus state appears periodically with a 30 second-silence state in between, and further clarify its possibility concerning a new class of phase transition, which is unusually driven by population. This work has relevance to acoustic synchronization and to general physics of phase transition.

  17. Some Bianchi type generalized ghost piligrim dark energy models in general relativity

    NASA Astrophysics Data System (ADS)

    Santhi, M. Vijaya; Aditya, Y.; Rao, V. U. M.

    2016-04-01

    In this paper, we consider Bianchi type-III, V and VI0 space-times filled with generalized ghost pilgrim dark energy (GGPDE) in general relativity. Here we assume the anisotropic distribution of GGPDE by introducing skewness parameters. To get deterministic solutions, we consider the scale factor a(t)=(tnet)^{ 1/k}, so called hybrid expansion, which yields a time dependent deceleration parameter, and exhibits a transition of the Universe from early decelerated phase to the recent accelerating phase. To describe the behavior of the obtained models we construct equation of state (ω_{Λ}), squared sound speed (vs2) parameters and ω_{Λ}-dot{ω }_{Λ}, r-s planes. It is worth mentioning here that the analysis of evolution parameters supports the concept of pilgrim dark energy (PDE). Also, these models remain stable for PDE parameter β =-0.5. Moreover, the cosmological planes correspond to Λ CDM limit as well as different well-known dark energy models.

  18. [The relation between population and health in a crisis].

    PubMed

    Bronfman, M

    1989-01-01

    This work argues that the economic crisis in Latin America resulting from structural adjustment programs and recession has had deleterious effects on the relationship between demographic factors and health. 2 works presented at the 1989 International Union for the Scientific Study of Population meeting in New Delhi considered the difficulty of demonstrating unambiguously the demographic effects of the economic crisis. This work, instead of looking at overall rates which may not have been greatly affected, focuses on 3 specific areas that reflect the relationship between population and health in the context of the crisis. Although the infant mortality rate has continued to decline in almost all countries and regions of Latin America during the crisis, the decline has been unequal in different sectors. A comparison of data from the 1987 National Survey of Fertility and Health in Mexico with that of the 1982 National Demographic Survey shows that rural infant mortality declined by only 1% between the 2 surveys, while urban infant mortality declined by 21%. An indicator of available services in the household showed the same increase inequality. Disaggregation of infant mortality data for Mexico suggests that even a presumably biological determinant, maternal age, loses much of its weight when socioeconomic factors are considered. Other studies, on the impact of maternal education, similarly indicate that the relationship is different for different social sectors. The infant mortality data taken together suggest that infant mortality continues to ba a valid indicator of social inequality, and that the crisis has had the effect of increasing inequality and worsening the relative conditions of the least advantaged. In the area of fertility, data from the 1989 National Survey of Fertility and Health in Mexico are used to argue that family planning programs are integral components of an authoritarian governmental political style. The survey indicated that sterilization is

  19. Anisotropic generalization of Matese & Whitman solution for compact star models in general relativity

    NASA Astrophysics Data System (ADS)

    Dayanandan, Baiju; Maurya, S. K.; Gupta, Y. K.; Smitha, T. T.

    2016-05-01

    We present a detailed investigation of the stability of anisotropic compact star models by introducing Matese and Whitman (Phys. Rev. D 11:1270, 1980) solution in general relativity. We have particularly looked into the detailed investigation of the measurements of basic physical parameters such as radial pressure, tangential pressure, energy density, red shift, sound velocity, masses and radii are affected by unknown effects such as loss, accretion and diffusion of mass. Those give insight into the characteristics of the compact astrophysical object with anisotropic matter distribution as well as the physical reality. The results obtained for the physical feature of compact stars such as, Her. X-1, RXJ 1856-37, SAX J1808.4-3658(SS2) and SAX J1808.4-3658(SS1) are compared to the recently observed massive compact object.

  20. Contamination from endocrine disrupters of the general population at low and high concentrations.

    PubMed

    Porta, Miquel; Pumarega, José; Gasull, Magda; Lopez, Tomàs

    2014-01-01

    Analyses of the concentrations of a given environmental compound usually show that most citizens have much lower concentrations than a certain minority, whose members have high body concentrations. Surveys of human exposure to chemicals do not usually integrate the number of chemical compounds detected per person and the concentration of each compound. This leaves untested relevant exposure situations, for example, whether individuals with low concentrations of some compounds have high concentrations of the other compounds. On scientific grounds, it is puzzling that this possibility, arithmetically and conceptually rather simple, has seldom if ever been tested in studies based on a representative sample of the general population. A study based on a representative sample of the general population of Catalonia (Spain) (Porta, Pumarega, & Gasull, 2012), which integrated the number of compounds detected per person and the concentration of each compound, found that more than half of the population had concentrations in the top quartile of 1 or more of the 19 persistent toxic substances (PTS) (pesticides and polychlorinated biphenyls) analyzed. Significant subgroups of the population accumulated PTS mixtures at high concentrations. For instance, 48% of women 60-74 years had concentrations of 6 or more PTS in the top quartile; half of the entire population had levels of 1-5 PTS above 500 ng/g, and less than 4% of citizens had all PTS in the lowest quartile. Thus, PTS concentrations appear low in most of the population only when each individual compound is looked at separately. It is not accurate to state that most of the population has low concentrations of PTS. The assessment of mixture effects must address the fact that most individuals are contaminated by PTS mixtures made of compounds at both low and high concentrations. PMID:24388190

  1. Spatial distribution and general population characteristics of mysid shrimps in the Westerschelde estuary (SW Netherlands)

    NASA Astrophysics Data System (ADS)

    Rappé, Karen; Fockedey, Nancy; Van Colen, Carl; Cattrijsse, Andre; Mees, Jan; Vincx, Magda

    2011-01-01

    The distribution and general population characteristics of five mysid shrimps were investigated in the period 2003-2005 in the Westerschelde estuary, a tidal temperate estuary situated along the Dutch-Belgian border. Multivariate analyses revealed that salinity predominantly governs the spatial distribution of Neomysis integer, Gastrosaccus spinifer, Schistomysis kervillei and Schistomysis spiritus while temperature, and to a lesser extent turbidity, control the distribution of Mesopodopsis slabberi. N. integer is a resident species in the mesohaline zone of the estuary, i.e. all life stages of the species are present in the estuary throughout the year. For the first time since decades N. integer inhabits the oligohaline zone of the estuary supposedly as a consequence of improved oxygen conditions in the upstream reaches. M. slabberi, the most abundant mysid in the Westerschelde, dominates the hyperbenthos of the mesohaline zone of the estuary. The polyhaline zone of the estuary is, most abundantly inhabited by M. slabberi, G. spinifer, S. kervillei and to a lesser extent by S. spiritus. The abundance of the latter four species is low in winter, probably due to a migration towards coastal waters to avoid colder temperatures in the estuary combined with an increased mortality after breeding. The sex ratio of all the mysid populations corresponds to the expected 1:1 female:male ratio and no salinity governed segregation is found between the different life stages of each mysid population. A seasonal variation exists in brood size in the N. integer population regardless of the body size, with a larger number of broods during winter and spring compared to the summer. In the other mysid populations the brood sizes vary only with the length of the ovigerous females. Our recent observations underline some general characteristics of mysid populations in the Westerschelde and provide novel insights in their life stage and sex specific population segregation, their brood

  2. Recent Results for Solar-System Tests of General Relativity

    NASA Astrophysics Data System (ADS)

    Anderson, J. D.; Lau, E. L.; Turyshev, S.; Williams, J. G.; Nieto, M. M.

    2002-05-01

    We use the current JPL archive of planetary positional data, along with the data-analysis implementation described by Newhall, Standish, and Williams, to solve for all the conventional parameters included in the JPL planetary ephemerides, plus four more parameters specific to tests of General Relativity. Spacecraft ranging data generated by the Deep Space Network (DSN) for NASA missions, and radar ranging measurements to Mercury and Venus are of primary importance. Venus radar ranging has been calibrated for topography by means of altimetry data from the Pioneer 12 Venus orbiter. Martian ranging data consists of orbiter data from Mariner 9 (1971 to 1972) and Mars Global Surveyor (1998 to 2000), as well as lander data from Viking (1976 to 1982) and Pathfinder (1997). In fitting the data, we weight the separate data sets, except for Mars, such that the assumed standard error for each data set is equal to the RMS residual for that particular set after the fit. For Mars, we use a standard error equal to 5 times the RMS residual for each of the four data sets. This is done to compensate for the systematic error from asteroid perturbations. We interpret the resulting parameter errors after the fit as realistic errors, as opposed to formal errors that would result from setting the Mars standard errors equal to their RMS values. The new values of the PPN parameters β and γ , and the solar gravitational quadrupole moment J2, are: β - 1 = -0.0010 +/- 0.0012, γ - 1 = -0.0015 +/- 0.0021, J2 = (2.3 +/- 5.2) x 10-7. The fourth parameter represents a possible time variation ˙ {G} in the gravitational constant. It is unchanged from what we reported last year at the Pasadena meeting. We conclude that the orbits of the inner planets are consistent with the Newtonian inverse-square law of attraction and with General Relativity at the post-Newtonian order O(v2/c2). This work was sponsored by NASA's Space Astrophysics Research and Analysis (SARA) program and was performed at the

  3. Use of generalized population ratios to obtain Fe XV line intensities and linewidths at high electron densities

    NASA Technical Reports Server (NTRS)

    Kastner, S. O.; Bhatia, A. K.

    1980-01-01

    A generalized method for obtaining individual level population ratios is used to obtain relative intensities of extreme ultraviolet Fe XV emission lines in the range 284-500 A, which are density dependent for electron densities in the tokamak regime or higher. Four lines in particular are found to attain quite high intensities in the high-density limit. The same calculation provides inelastic contributions to linewidths. The method connects level populations and level widths through total probabilities t(ij), related to 'taboo' probabilities of Markov chain theory. The t(ij) are here evaluated for a real atomic system, being therefore of potential interest to random-walk theorists who have been limited to idealized systems characterized by simplified transition schemes.

  4. Quality of life impairment associated with body dissatisfaction in a general population sample of women

    PubMed Central

    2013-01-01

    Background In order to elucidate the individual and community health burden of body dissatisfaction (BD), we examined impairment in quality of life associated with BD in a large, general population sample of women. Methods Self-report measures of BD, health-related quality of life (SF-12 Physical and Mental Component Summary scales) and subjective quality of life (WHOQOL-BREF Psychological Functioning and Social Relationships subscales) were completed by 5,255 Australian women aged 18 to 42 years. Results Most participants (86.9%) reported some level of dissatisfaction with their weight or shape and more than one third (39.4%) reported moderate to marked dissatisfaction. Higher levels of BD were associated with poorer quality of life for all items of both quality of life measures, the degree of impairment being proportional to the degree of BD. Associations were strongest for items tapping mental health and psychosocial functioning, although greater BD was associated with substantially increased risk of impairment in certain aspects of physical health even when controlling for body weight. Post-hoc analysis indicated that the observed associations between BD and quality of life impairment were not accounted for by an association between BD and eating disorder symptoms. Conclusions In women, BD is associated with marked impairment in aspects of quality of life relating to mental health and psycho-social functioning and at least some aspects of physical health, independent of its association with body weight and eating disorder symptoms. Greater attention may need to be given to BD as a public health problem. The fact that BD is “normative” should not be taken to infer that it is benign. PMID:24088248

  5. How absorption selected galaxies trace the general high-redshift galaxy population

    NASA Astrophysics Data System (ADS)

    Christensen, Lise

    2015-08-01

    Strong absorption lines seen in quasar spectra arise when the lines of sight to the quasars intersect intervening galaxies. The associated metal absorption lines from the strongest absorption lines, the damped Lyman alpha absorbers (DLAs), allow us to trace the metallicity of galaxies back to redshifts z>5. Typical metallicities range from 0.1-100% solar metallicities with a huge scatter at any given redshift. Understanding the nature of galaxies that host DLAs is one strategy to probe the early phase and origin of stars in the outskirts of present-day galaxy disks.The search for emission from the elusive high-redshift DLA galaxies has reached a mature state now that we have determined how to best identify the absorbing galaxies. From a growing number of emission-line detections from DLA galaxies at redshifts ranging between 0.1 and 3, we can analyse galaxies in both absorption and emission, and probe the gas-phase metallicities in the outskirts and halos of the galaxies.By combining information for galaxies seen in emission and absorption, I will show that there is a relation between DLA metallicities and the host galaxy luminosities similar to the well-known the mass-metallicity relation for luminosity selected galaxies. This implies that DLA galaxies are drawn from the general population of low- to intermediate mass galaxies. We can determine a metallicity gradient in the extended halo of the galaxies out to ~40 kpc, and this allows us to reproduce observed galaxy correlation functions derived from conventional samples of luminosity selected galaxies.

  6. The Association between Dietary Patterns and Semen Quality in a General Asian Population of 7282 Males

    PubMed Central

    Liu, Chin-Yu; Chou, Yu-Ching; Chao, Jane C. -J.; Hsu, Chien-Yeh; Cha, Tai-Lung; Tsao, Chih-Wei

    2015-01-01

    Objective To explore the associations between different dietary patterns and semen quality in a general Asian male population. Methods Cross-sectional study. Healthy Taiwanese men aged 18 years or older who participated in a standard medical screening program from 2008-2013 run by a private firm were included in this study. Semen parameters including sperm concentration (SC), total sperm motility (TSM), progressive motility (PRM) and normal sperm morphology (NSM) were recorded. A dietary questionnaire was used to categorize the participants into 5 groups: “Healthy diet”, “Western diet”, “High-carbohydrate diet”, “High sweet snacks & sugar-sweetened drinks” and “High-sodium diet”. Results A total of 7282 men completed the questionnaire regarding dietary pattern, and examination of anthropometric indexes was performed and laboratory data were obtained. A high intake of a “Western diet” resulted in statistically linear declines of SC and NSM (P < 0.001 and P < 0.001). Similarly, a greater intake of “High sweet snacks & sugar-sweetened drinks” was associated with a lower SC (P = 0.001). Increased intake of a “High-carbohydrate diet” was related to higher prevalences of abnormal TSM and PRM (P = 0.012 and P = 0.025). Similarly, a greater intake of a “High-sodium diet” was correlated with an elevated prevalence of abnormal NSM (P = 0.035). Conclusions This study showed that a greater intake of a “Western diet” is associated with poorer SC and NSM, a “High sweet snacks and sugar-sweetened drinks” intake is correlated with a lower SC, and high-carbohydrate food is related to elevated prevalences of abnormal TSM and PRM. PMID:26218796

  7. Environmental Factors Related to Multiple Sclerosis in Indian Population

    PubMed Central

    D’Cunha, Anita; Mustafa, Sharik

    2015-01-01

    Background Multiple sclerosis (MS) is less prevalent among Indians when compared to white populations. Genetic susceptibility remaining the same it is possible that environmental associations may have a role in determining disease prevalence. Aims To determine whether childhood infections, vaccination status, past infection with Helicobacter pylori (H.pylori), diet, socioeconomic and educational status were associated with MS. Material and Methods 139 patients and 278 matched control subjects were selected. A validated environmental exposure questionnaire was administered. Estimation of serum H.pylori IgG antibody was done by ELISA. Patients and controls were genotyped for HLA-DRB1*15:01. Results In our cohort a significant association was seen with measles (p <0.007), vegetarian diet (p < 0.001, higher educational status (p <0.0001) and urban living (p <0.0001). An inverse relationship was seen with H.Pylori infection and MS (p <0.001). Measles infection (OR 6.479, CI 1.21- 34.668, p< 0.029) and high educational status (OR 3.088, CI 1.212- 7.872, p< 0.018) were significant risk factors associated with MS. H.pylori infection was inversely related to MS (OR 0. 319, CI 0.144- 0.706, p <0.005). Conclusions Environmental influences may be important in determining MS prevalence. PMID:25902359

  8. A Sex-Specific Comparison of Major Depressive Disorder Symptomatology in the Canadian Forces and the General Population

    PubMed Central

    Erickson, Julie; Kinley, D Jolene; Bolton, James M; Zamorski, Mark A; Enns, Murray W; Sareen, Jitender

    2014-01-01

    Objective: To compare major depressive disorder (MDD) symptomatology within men and women in a large, representative sample of Canadian military personnel and civilians. Method: We used the Canadian Community Health Survey: Mental Health and Well-Being (Cycle 1.2 and Canadian Forces Supplement) (n = 36 984 and n = 8441, respectively) to compare past-year MDD symptomatology among military and civilian women, and military and civilian men. Logistic regression models were used to determine differences in the types of depressive symptoms endorsed in each group. Results: Men in the military with MDD were at lower odds than men in the general population to endorse numerous symptoms of depression, such as hopelessness (adjusted odds ratio [AOR] 0.44; 99% CI 0.23 to 0.83) and inability to cope (AOR 0.53; 99% CI 0.31 to 0.92). Military women with MDD were at lower odds of thinking about their death (AOR 0.52; 99% CI 0.32 to 0.86), relative to women with MDD in the general population. Conclusion: Different MDD symptomatology among males and females in the military, compared with those in the general population, may reflect selection effects (for example, personality characteristics and patterns of comorbidity) or occupational experiences unique to military personnel. Future research examining the mechanisms behind MDD symptomatology in military personnel and civilians is required. PMID:25007423

  9. OPTIS A Satellite test of Special and General Relativity

    NASA Astrophysics Data System (ADS)

    Dittus, H.; Lämmerzahl, C.; Peters, A.; Schiller, S.

    OPTIS has been proposed as a small satellite platform in a high elliptical orbit (apogee 40,000 km, perigee 10,000 km) and is designed for high precision tests of foundations of Special and General Relativity. The experimental set-up consists of two ultrastable Nd:YAG lasers, three crossed optical resonators (monolithic cavities), an ensemble of atomic clocks, an optical comb generator, laser tracking devices and a drag-free control system. OPTIS enables improved tests of (1) the isotropy and (2) constancy of the speed of light, (3) special relativistic time dilation, (4) the universality of the gravitational redshift by comparison of various clocks, can measure (5) the absolute value of the gravitational redshift, (6) the Lense-Thirring effect and (7) the perigee advance and (8) can make a test of a hypothetical Yukawa part in the gravitational potential. To avoid any influence from atmospheric drag, solar radiation, or Earth albedo, the satellite needs drag-free control to depress the residual acceleration down to 10 -14 m/s 2 in the frequency range between 10 -2 and 10 -3 Hz. Precise thermal control must be used to stabilize the cavity temperature to within one part in 10 7 at time scales of 100 s and to one part in 10 5 on the orbit time scale.

  10. Cosmology in time asymmetric extensions of general relativity

    NASA Astrophysics Data System (ADS)

    Leon, Genly; Saridakis, Emmanuel N.

    2015-11-01

    We investigate the cosmological behavior in a universe governed by time asymmetric extensions of general relativity, which is a novel modified gravity based on the addition of new, time-asymmetric, terms on the Hamiltonian framework, in a way that the algebra of constraints and local physics remain unchanged. Nevertheless, at cosmological scales these new terms can have significant effects that can alter the universe evolution, both at early and late times, and the freedom in the choice of the involved modification function makes the scenario able to produce a huge class of cosmological behaviors. For basic ansatzes of modification, we perform a detailed dynamical analysis, extracting the stable late-time solutions. Amongst others, we find that the universe can result in dark-energy dominated, accelerating solutions, even in the absence of an explicit cosmological constant, in which the dark energy can be quintessence-like, phantom-like, or behave as an effective cosmological constant. Moreover, it can result to matter-domination, or to a Big Rip, or experience the sequence from matter to dark energy domination. Additionally, in the case of closed curvature, the universe may experience a cosmological bounce or turnaround, or even cyclic behavior. Finally, these scenarios can easily satisfy the observational and phenomenological requirements. Hence, time asymmetric cosmology can be a good candidate for the description of the universe.

  11. Classical tests of General Relativity in thick branes

    NASA Astrophysics Data System (ADS)

    Dahia, F.; de Albuquerque Silva, Alex

    2015-02-01

    Classical tests of General Relativity in braneworld scenarios have been investigated recently with the purpose of posing observational constraints on the parameters of some models of infinitely thin brane. Here we consider the motion of test particles in a thick brane scenario that corresponds to a regularized version of the Garriga-Tanaka solution, which describes a black hole solution in RSII model, in the weak field regime. By adapting a mechanism previously formulated in order to describe the confinement of massive tests particles in a domain wall (which simulates classically the trapping of the Dirac field in a domain wall), we study the influence of the brane thickness on the four-dimensional (4D) path of massless particles. Although the geometry is not warped and, therefore, the bound motion in the transverse direction is not decoupled from the movement in the 4D-world, we can find an explicit solution for the light deflection and the time delay, if the motion in the fifth direction is a high frequency oscillation. We verify that, owing to the transverse motion, the light deflection and the time delay depend on the energy of the light rays. This feature may lead to the phenomenon of gravitational rainbow. We also consider the problem from a semi-classical perspective, investigating the effects of the brane thickness on the motion of the zero-mode in the 4D-world.

  12. Testing general relativity with present and future astrophysical observations

    NASA Astrophysics Data System (ADS)

    Berti, Emanuele; Barausse, Enrico; Cardoso, Vitor; Gualtieri, Leonardo; Pani, Paolo; Sperhake, Ulrich; Stein, Leo C.; Wex, Norbert; Yagi, Kent; Baker, Tessa; Burgess, C. P.; Coelho, Flávio S.; Doneva, Daniela; De Felice, Antonio; Ferreira, Pedro G.; Freire, Paulo C. C.; Healy, James; Herdeiro, Carlos; Horbatsch, Michael; Kleihaus, Burkhard; Klein, Antoine; Kokkotas, Kostas; Kunz, Jutta; Laguna, Pablo; Lang, Ryan N.; Li, Tjonnie G. F.; Littenberg, Tyson; Matas, Andrew; Mirshekari, Saeed; Okawa, Hirotada; Radu, Eugen; O'Shaughnessy, Richard; Sathyaprakash, Bangalore S.; Van Den Broeck, Chris; Winther, Hans A.; Witek, Helvi; Emad Aghili, Mir; Alsing, Justin; Bolen, Brett; Bombelli, Luca; Caudill, Sarah; Chen, Liang; Degollado, Juan Carlos; Fujita, Ryuichi; Gao, Caixia; Gerosa, Davide; Kamali, Saeed; Silva, Hector O.; Rosa, João G.; Sadeghian, Laleh; Sampaio, Marco; Sotani, Hajime; Zilhao, Miguel

    2015-12-01

    One century after its formulation, Einstein's general relativity (GR) has made remarkable predictions and turned out to be compatible with all experimental tests. Most of these tests probe the theory in the weak-field regime, and there are theoretical and experimental reasons to believe that GR should be modified when gravitational fields are strong and spacetime curvature is large. The best astrophysical laboratories to probe strong-field gravity are black holes and neutron stars, whether isolated or in binary systems. We review the motivations to consider extensions of GR. We present a (necessarily incomplete) catalog of modified theories of gravity for which strong-field predictions have been computed and contrasted to Einstein's theory, and we summarize our current understanding of the structure and dynamics of compact objects in these theories. We discuss current bounds on modified gravity from binary pulsar and cosmological observations, and we highlight the potential of future gravitational wave measurements to inform us on the behavior of gravity in the strong-field regime.

  13. The Cavenish Experiment, General Relativity, Nuclear Quantum Gravitation

    NASA Astrophysics Data System (ADS)

    Kotas, Ronald R.

    2008-04-01

    The Cavendish Experiment - Demonstration clearly shows the Gravitational attraction between two masses, which is a force proportional to the Newtonian mechanics. General Relativity fails the Cavendish Experiment because there is no force between two gravitating masses but instead pictures a fallacious time-space concept. GR has no definitive proofs. The very hot corona and not GR cause the bending of light near and about the Sun The Perihelion of Mercury, the 43 arc seconds is 3.8 x 10-12 of the total and is not a proof of GR. This Perihelion rotation is nothing more than another mode of Newtonian mechanics explained by Newtonian mechanics. Each orbit is an ellipse, a Newtonian function that adds together because of Newtonian functions and accounts for any movement and advancement of Mercury. Because of gravity and speed changes, clocks change, time does not change. Other proofs are not valid because they are Quantum effects or plainly Newtonian refractions. Nuclear Quantum Gravitation clearly explains the gravitational force between two gravitating masses because of alternating electromagnetic functions in nuclei of matter. Some 20 proofs and indications prove this, plainly and clearly. Any gravity theory that does not conform to the Cavendish demonstration is not a viable theory of gravity. With Nuclear Quantum Gravitation, the Forces are plainly and coherently unified.

  14. Testing General Relativity with the Event Horizon Telescope

    NASA Astrophysics Data System (ADS)

    Benkevitch, Leonid; Fish, V. L.; Johannsen, T.; Akiyama, K.; Broderick, A. E.; Psaltis, D.; Doeleman, S.; Monnier, J. D.; Baron, F.

    2013-01-01

    Strong gravitational lensing of light near black holes is one of the effects predicted by general relativity (GR). Emission close to a black hole will typically be lensed to illuminate the last photon orbit, creating a feature known as the black hole 'shadow' or 'silhouette'. The precise size and shape of the shadow is dependent on black hole mass, spin, and the space-time metric. The Event Horizon Telescope (EHT) is a (sub)mm VLBI network that can achieve Schwarzschild Radius scale resolution on SgrA*, the 4 million solar mass black hole at the Galactic Center. Here we present initial studies of how recent and future EHT observations of SgrA* can be used to test the No-Hair theorem by searching for deviations from the expected shadow morphology. We have developed a pipeline for producing synthetic EHT data sets from black hole emission models using perturbed space-time metrics that violate the No-Hair theorem. Employing imaging and modelfitting algorithms tailored for EHT data, we extract parameters of the black hole shadow. Preliminary results indicate that the EHT can provide a new way to test GR in the strong gravity regime that is complementary to techniques in other fields.

  15. Scale-invariant alternatives to general relativity. II. Dilaton properties

    NASA Astrophysics Data System (ADS)

    Karananas, Georgios K.; Shaposhnikov, Mikhail

    2016-04-01

    In the present paper, we revisit gravitational theories which are invariant under TDiffs—transverse (volume-preserving) diffeomorphisms and global scale transformations. It is known that these theories can be rewritten in an equivalent diffeomorphism-invariant form with an action including an integration constant (cosmological constant for the particular case of non-scale-invariant unimodular gravity). The presence of this integration constant, in general, breaks explicitly scale invariance and induces a runaway potential for the (otherwise massless) dilaton, associated with the determinant of the metric tensor. We show, however, that if the metric carries mass dimension [GeV] -2 , the scale invariance of the system is preserved, unlike the situation in theories in which the metric has mass dimension different from -2 . The dilaton remains massless and couples to other fields only through derivatives, without any conflict with observations. We observe that one can define a specific limit for fields and their derivatives (in particular, the dilaton goes to zero, potentially related to the small distance domain of the theory) in which the only singular terms in the action correspond to the Higgs mass and the cosmological constant. We speculate that the self-consistency of the theory may require the regularity of the action, leading to the absence of the bare Higgs mass and cosmological constant, whereas their small finite values may be generated by nonperturbative effects.

  16. Cosmological nonlinear structure formation in full general relativity

    NASA Astrophysics Data System (ADS)

    Torres, José M.; Alcubierre, Miguel; Diez-Tejedor, Alberto; Núñez, Darío

    2014-12-01

    We perform numerical evolutions of cosmological scenarios using a standard general relativistic code in spherical symmetry. We concentrate on two different situations: initial matter distributions that are homogeneous and isotropic, and perturbations to those that respect the spherical symmetry. As matter models we consider the case of a pressureless perfect fluid, i.e. dust, and the case of a real massive scalar field oscillating around the minimum of the potential. Both types of matter have been considered as possible dark matter candidates in the cosmology literature, dust being closely related to the standard cold dark matter paradigm. We confirm that in the linear regime the perturbations associated with these types of matter grow in essentially the same way, the main difference being that in the case of a scalar field the dynamics introduce a cutoff in the power spectrum of the density perturbations at scales comparable with the Compton wavelength of the field. We also follow the evolutions well beyond the linear regime showing that both models are able to form structure. In particular we find that, once in the nonlinear regime, perturbations collapse faster in a universe dominated by dust. This is expected to delay the formation of the first structures in the scalar field dark matter scenario with respect to the standard cold dark matter one.

  17. A Time Domain Waveform for Testing General Relativity

    NASA Astrophysics Data System (ADS)

    Huwyler, Cédric; Porter, Edward K.; Jetzer, Philippe

    2015-05-01

    Gravitational-wave parameter estimation is only as good as the theory the waveform generation models are based upon. It is therefore crucial to test General Relativity (GR) once data becomes available. Many previous works, such as studies connected with the ppE framework by Yunes and Pretorius, rely on the stationary phase approximation (SPA) to model deviations from GR in the frequency domain. As Fast Fourier Transform algorithms have become considerably faster and in order to circumvent possible problems with the SPA, we test GR with corrected time domain waveforms instead of SPA waveforms. Since a considerable amount of work has been done already in the field using SPA waveforms, we establish a connection between leading-order-corrected waveforms in time and frequency domain, concentrating on phase-only corrected terms. In a Markov Chain Monte Carlo study, whose results are preliminary and will only be available later, we will assess the ability of the eLISA detector to measure deviations from GR for signals coming from supermassive black hole inspirals using these corrected waveforms.

  18. Bose gas with generalized dispersion relation plus an energy gap

    NASA Astrophysics Data System (ADS)

    Solis, M. A.; Martinez, J. G.; Garcia, J.

    We report the critical temperature, the condensed fraction, the internal energy and the specific heat for a d-dimensional Bose gas with a generalized dispersion relation plus an energy gap, i.e., ɛ =ɛ0 for k = 0 and ɛ =ɛ0 + Δ +csks , for k > 0 , where ℏk is the particle momentum, ɛ0 the lowest particle energy, cs a constant with dimension of energy multiplied by a length to the power s > 0 . When Δ > 0 , a Bose-Einstein critical temperature Tc ≠ 0 exists for any d / s >= 0 at which the internal energy shows a peak and the specific heat shows a jump. The critical temperature and the specific heat jump increase as functions of the gap but they decrease as functions of d / s . Thermodynamic properties are ɛ0 independent since this is just a reference energy. For Δ = 0 we recover the results reported in Ref. [1]. V. C. Aguilera-Navarro, M. de Llano y M. A. Solís, Eur. J. Phys. 20, 177 (1999). We acknowledge partial support from Grants PAPIIT IN111613 and CONACyT 221030.

  19. An Economic Analysis of Cell-Free DNA Non-Invasive Prenatal Testing in the US General Pregnancy Population

    PubMed Central

    Benn, Peter; Curnow, Kirsten J.; Chapman, Steven; Michalopoulos, Steven N.; Hornberger, John; Rabinowitz, Matthew

    2015-01-01

    Objective Analyze the economic value of replacing conventional fetal aneuploidy screening approaches with non-invasive prenatal testing (NIPT) in the general pregnancy population. Methods Using decision-analysis modeling, we compared conventional screening to NIPT with cell-free DNA (cfDNA) analysis in the annual US pregnancy population. Sensitivity and specificity for fetal aneuploidies, trisomy 21, trisomy 18, trisomy 13, and monosomy X, were estimated using published data and modeling of both first- and second trimester screening. Costs were assigned for each prenatal test component and for an affected birth. The overall cost to the healthcare system considered screening costs, the number of aneuploid cases detected, invasive procedures performed, procedure-related euploid losses, and affected pregnancies averted. Sensitivity analyses evaluated the effect of variation in parameters. Costs were reported in 2014 US Dollars. Results Replacing conventional screening with NIPT would reduce healthcare costs if it can be provided for $744 or less in the general pregnancy population. The most influential variables were timing of screening entry, screening costs, and pregnancy termination rates. Of the 13,176 affected pregnancies undergoing screening, NIPT detected 96.5% (12,717/13,176) of cases, compared with 85.9% (11,314/13,176) by conventional approaches. NIPT reduced invasive procedures by 60.0%, with NIPT and conventional methods resulting in 24,596 and 61,430 invasive procedures, respectively. The number of procedure-related euploid fetal losses was reduced by 73.5% (194/264) in the general screening population. Conclusion Based on our analysis, universal application of NIPT would increase fetal aneuploidy detection rates and can be economically justified. Offering this testing to all pregnant women is associated with substantial prenatal healthcare benefits. PMID:26158465

  20. A Deflection test of General Relativity Using the FAME Data

    NASA Astrophysics Data System (ADS)

    Reasenberg, R. D.

    2000-05-01

    The deflection of light by the Sun provides one of the classical tests of general relativity. The deflection is closely related to the Shapiro time delay and, in the context of the PPN formalism, each has an overall coefficient of (1 + γ ) / 2. The current published set of strong determinations of the PPN parameter γ are based on Viking radio delay (Reasenberg et al., 1979, ApJL: 1.000 +- 0.002), VLBI data intended for geodesy (Robertson et al., 1991, Nature: 1.0002 +- 0.002), VLBI data for relativity (Lebach et al., 1995, Phys. Rev. Lett: 0.9996 +- 0.0016), and Hipparcos (Froeschle et al., 1997, ESA SP-402: 0.997 +- 0.003). FAME will observe 40 million stars about 1000 times each during a 2.5 year mission, and a 2.5 year extended mission is planned. For V-mag = 9, its nominal measurement accuracy is 1.1 mas along the great circle defined by the spin direction, which remains about 45 deg from the Sun direction as it precesses around the Sun. Although FAME observations are made as close as 45 deg from the Sun, those have zero sensitivity because they are made in the wrong direction. At 90 deg from the Sun, the deflection seen from Earth is 4.1 mas, which would yield a SNR of 3.7 for FAME, were it not for the ``cosine term." The most sensitive measurements are made when the spacecraft has rotated the view port 45 deg from the observations closest to the Sun -- Sun-star angle of 60 deg -- yielding a single-measurement SNR of 4. A preliminary propagation-of-error analysis shows that a 2.5 year FAME mission has the sensitivity to measure γ with an uncertainty of 3.4 10-5, using all stars from V-mag 5 to 15. However, as was the case for Hipparcos, correlations and systematic errors will result in a larger uncertainty, perhaps 3 to 10 fold larger. This work has been supported by the Smithsonian Astrophysical Observatory. FAME is a NASA MIDEX mission with the PI at the U.S. Naval Observatory.

  1. The new cell culture smallpox vaccine should not be offered to the general population.

    PubMed

    Mortimer, Philip P

    2003-01-01

    Cell based smallpox vaccines are to be welcomed, but any decision to vaccinate whole populations must await firstly better intelligence about the gravity of the threat from bioterrorists, including their ability to release smallpox in such a way that wide dissemination could take place; secondly evidence that vaccines grown in cell culture are protective and safe; and thirdly that the vaccines would be generally acceptable and their introduction would not compromise the rest of national immunisation programmes. Smallpox vaccination should not be offered to the general population until these uncertainties have been resolved, by which time bioterrorism might possibly have been overcome or the development of antiviral treatment might have made renewed smallpox vaccination unnecessary. Meanwhile, preparations for rapid deployment of the historically well-tried containment measures at the epicentres of any smallpox release should proceed, their effectiveness should be tested, and their adequacy kept under review. PMID:12516059

  2. [Population Education: Its Goals, Related Guidelines, and Considerations for Curriculum.

    ERIC Educational Resources Information Center

    Jayasuriya, J. E.

    Many countries today recognize the need to initiate a population education program within the school curriculum at all levels. In developing countries, many changes have been brought about by population increases. Enormous needs have been created for housing, schools, medical care, food, and employment. These needs, however, are not being met…

  3. Age-dependence of lipid parameters in the general population and vegetarians.

    PubMed

    Richter, V; Rassoul, F; Hentschel, B; Kothe, K; Krobara, M; Unger, R; Purschwitz, K; Rotzsch, W; Thiery, J; Muradian, K

    2004-06-01

    Age-dependent changes of lipid metabolism may arise both as a result of mechanisms of biological ageing and factors influencing age-dependent changes. To study possible influences of nutrition and life-style of vegetarians on age-dependence of lipid parameters, subjects of general population were compared with vegetarians. In the frame of population-based lipid screening projects in the city of Leipzig/Germany (Lipid Study Leipzig, LSL) 10 550 subjects (3,816 men and 6,734 women, age 18-99 years) of general population were compared with 417 vegetarians (vegans, lacto-vegetarians, lacto-ovo-vegetarians, 148 men and 269 women, age 18-93 years). Most of the vegetarians included in the study were members of the German Society of Vegetarians. The study program included capillary blood cholesterol measurements and the determination of high-density lipoprotein (HDL)-cholesterol, the measurement of other cardiovascular risk factors and the evaluation of dietary and life-style factors. Evaluation of cardiovascular risk profile within LSL was connected with individual consultation. The mean total cholesterol and non-HDL-cholesterol level and the total: HDL-cholesterol ratio showed the expected age-dependence, with maximum values within the decade 60-70 years. Vegetarians showed lower total and non-HDL-cholesterol levels in comparison with the general population. Furthermore, the age-dependent increase of these parameters is less pronounced under the conditions of vegetarian nutrition and life-style. Especially in young adulthood a significant difference is observed. Thus, the results of the present study reveal the role of nutritional and life-style factors that determine the lipid profile on a population basis and suggest that the known age-dependent rise of the level of atherogenic plasma lipoproteins is partly preventable. PMID:15224241

  4. Negative relationships between population density and metabolic rates are not general.

    PubMed

    Yashchenko, Varvara; Fossen, Erlend Ignacio; Kielland, Øystein Nordeide; Einum, Sigurd

    2016-07-01

    Population density has recently been suggested to be an important factor influencing metabolic rates and to represent an important 'third axis' explaining variation beyond that explained by body mass and temperature. In situations where population density influences food consumption, the immediate effect on metabolism acting through specific dynamic action (SDA), and downregulation due to fasting over longer periods, is well understood. However, according to a recent review, previous studies suggest a more general effect of population density per se, even in the absence of such effects. It has been hypothesized that this results from animals performing anticipatory responses (i.e. reduced activity) to expected declines in food availability. Here, we test the generality of this finding by measuring density effects on metabolic rates in 10 clones from two different species of the zooplankton Daphnia (Daphnia pulex Leydig and D. magna Straus). Using fluorescence-based respirometry, we obtain high-precision measures of metabolism. We also identify additional studies on this topic that were not included in the previous review, compare the results and evaluate the potential for measurement bias in all previous studies. We demonstrate significant variation in mass-specific metabolism among clones within both species. However, we find no evidence for a negative relationship between population density and mass-specific metabolism. The previously reported pattern also disappeared when we extended the set of studies analysed. We discuss potential reasons for the discrepancy among studies, including two main sources of potential bias (microbial respiration and declining oxygen consumption due to reduced oxygen availability). Only one of the previous studies gives sufficient information to conclude the absence of such biases, and consistent with our results, no effect of density on metabolism was found. We conclude that population density per se does not have a general effect

  5. Cause-specific excess mortality among dialysis patients: comparison with the general population in Japan.

    PubMed

    Wakasugi, Minako; Kazama, Junichiro James; Yamamoto, Suguru; Kawamura, Kazuko; Narita, Ichiei

    2013-06-01

    Despite significant therapeutic advances, mortality of dialysis patients remains unacceptably high. The aim of this study is to compare mortality and its causes in dialysis patients with those in the general Japanese population. We used data for 2008 and 2009 from the Japanese Society for Dialysis Therapy registry and a national Vital Statistics survey. Cardiovascular mortality was defined as death attributed to heart failure, cerebrovascular disorders, myocardial infarction, hyperkalemia/sudden death, and pulmonary thromboembolism. Non-cardiovascular mortality was defined as death attributed to infection, malignancies, cachexia/uremia, chronic hepatitis/cirrhosis, ileus, bleeding, suicide/refusal of treatment, and miscellaneous. We calculated standardized mortality ratios and age-adjusted mortality differences between dialysis patients and the general population for all-cause, cardiovascular versus non-cardiovascular, and cause-specific mortality. During the 2-year study period, there were 2,284,272 and 51,432 deaths out of 126 million people and 273,237 dialysis patients, respectively. The standardized mortality ratio for all-cause mortality was 4.6 (95% confidence interval, 4.6-4.7) for the dialysis patients compared to the general population. Age-adjusted mortality differences for cardiovascular and non-cardiovascular disease were 33.1 and 30.0 per 1000 person-years, respectively. The standardized mortality rate ratios were significant for all cause-specific mortality rates except accidental death. Our study revealed that excess mortality in dialysis patients compared to the general population in Japan is large, and differs according to age and cause of death. Cause-specific mortality studies should be planned to improve life expectancies of dialysis patients. PMID:23735145

  6. Comparison of Abnormal Cervical Cytology from HIV Positive Women, Female Sex Workers and General Population

    PubMed Central

    Vafaei, Homeira; Asadi, Nasrin; Foroughinia, Leila; Salehi, Alireza; Kuhnavard, Safieh; Akbarzadeh, Mojgan; Ravanbod, Hamid Reza; Mohamadalian, Ferdos; Kasraeian, Maryam

    2015-01-01

    Background Sex workers and HIV seropositive women are at high risk of abnormal cervical cytology. The objective of this study was to compare the cervical cytology among three groups of women: active sex workers, HIV-infected women, and general population in Iran. Methods This was a cross-sectional study performed in Hazrat Zeinab, Lavan clinics and drop in center (DIC) in Shiraz, Iran. This study was performed from October 2009 to October 2011. A total of 266 patients were assigned into three groups: sex-workers (85), HIV positive patients (100), and general population (81). Pap smear was performed for all participants from the exocervix and endocervix, using a plastic Ayres’s spatula and cytobrush. The samples were sent to a pathology center, using a liquid-based media.  Results The risk of cervical infection in sex workers and HIV positive women was greater than the general population (OR=5.47, 95% confidence interval [CI]:2.24, 13.40), (OR=3.71, 95% CI:1.52, 9.09), respectively. The frequency of abnormal cervical cytology in the HIV positive and sex worker groups was higher than the general population (OR=6. 76, 95% CI:2.25, 20.32), (OR=3. 80, 95% CI:1.19, 12.07), respectively. Low-grade squamous intraepithelial lesion (LSIL) and high-grade squamous intraepithelial lesion (HSIL) were associated with CD4 cell count<200Í106/L, P=0.021 and P<0.001, respectively. Conclusion Vaginal infections were seen more often in the sex worker group, and abnormal cervical cytology was greater in the HIV positive group. PMID:26005687

  7. Trends in the treatment of alcohol problems in the US general population, 1979 through 1990.

    PubMed Central

    Weisner, C; Greenfield, T; Room, R

    1995-01-01

    OBJECTIVES. The purpose of this study was to conduct a comprehensive analysis of alcohol-treatment service utilization trends in the general population during the 1980s. METHODS. Three national surveys of the US household population (1979, 1984, and 1990) were used for trend analysis of treatment utilization. Trends in demographic characteristics of persons with lifetime treatment rates and particular types of treatment were examined by means of logistic regression analysis, controlling for alcohol problem severity and other variables. RESULTS. Substantial increases in the numbers reporting treatment were found. In all surveys, Alcoholics Anonymous was the treatment used most frequently and its use increased most, especially for women. Men were more likely than women (odds ratio [OR] = 2.01, 95% confidence interval [CI] = 1.20, 5.39) and unmarried persons were twice as likely as married persons to have been treated [corrected]. Social consequences carried more predictive power than dependence symptoms. CONCLUSIONS. From a general population perspective, while overall treatment capacity has increased, the structural changes in the public/private balance of services have not positively affected the representation of women or other characteristics of the treatment population. PMID:7832262

  8. Awareness to sun exposure and use of sunscreen by the general population.

    PubMed

    Al Robaee, Ahmad A

    2010-11-01

    Sun exposure has a pathogenic effect on the development of skin cancer, whose prevalence increases worldwide. Educational programs are carried out to change high risk sun exposure behaviours. The aim of this study was to evaluate the knowledge of Saudi population regarding sun exposure and the risk of skin cancers, as well as to study their sun-protective attitudes and practices. A cross-sectional population-based survey using specially devised questionnaire on a stratified random sample of general population in Qassim Province between January and March 2010. One thousand three hundred and seventy six persons participated in the study. A high sun exposure of more than 10 hours per week was reported by 661 persons (48%). Fifty six percent of respondents were aware of the association between sun exposure and skin cancer but the rate of sun screen use was only 8.3%. Socio-demographic factors more likely to be associated with sunscreen use were: females, higher social class, higher levels of education, type 4 skin and married individuals. This study has indicated a low rate of sunscreen use by our population despite reasonably good knowledge about the hazards of sun exposure. This necessitates the need for health education program. We hope that the results of our study will be used for setting up a sun policy for Saudi general public. PMID:21108614

  9. Usage patterns of aromatherapy among the French general population: A descriptive study focusing on dermal exposure.

    PubMed

    Dornic, N; Ficheux, A S; Roudot, A C; Saboureau, D; Ezzedine, K

    2016-04-01

    Although likely benefits of aromatherapy are well documented, little is known about essential oils consumption and exposure to molecules present in the oils. The aim of our study was to determine usage patterns of 12 types of essential oils among a quite large panel, sorted per sex and quintile of age from birth to 70. A survey was conducted in September 2014 among 1507 French individuals, selected to build a representative panel of the general population. The key point of our study, apart from the fact that it has never been done among general population, was the focus on dermal exposure. Information about types of essential oils used, skin areas exposed, frequencies and quantities were collected. Our work revealed that some sub-populations could be significantly exposed to molecules of toxicological concern, especially in terms of skin sensitization. This work is the first step to assess human exposure to these molecules, and will help safety authorities and risk managers to protect the population. PMID:26826550

  10. Prevalence, survival analysis and multimorbidity of chronic diseases in the general veterinarian-attended horse population of the UK.

    PubMed

    Welsh, Claire E; Duz, Marco; Parkin, Timothy D H; Marshall, John F

    2016-09-01

    The average age of the global human population is increasing, leading to increased interest in the effects of chronic disease and multimorbidity on health resources and patient welfare. It has been posited that the average age of the general veterinarian-attended horse population of the UK is also increasing, and therefore it could be assumed that chronic diseases and multimorbidity would pose an increasing risk here also. However, evidence for this trend in ageing is very limited, and the current prevalence of many chronic diseases, and of multimorbidity, is unknown. Using text mining of first-opinion electronic medical records from seven veterinary practices around the UK, Kaplan-Meier and Cox proportional hazard modelling, we were able to estimate the apparent prevalence among veterinarian-attended horses of nine chronic diseases, and to assess their relative effects on median life expectancy following diagnosis. With these methods we found evidence of increasing population age. Multimorbidity affected 1.2% of the study population, and had a significant effect upon survival times, with co-occurrence of two diseases, and three or more diseases, leading to 6.6 and 21.3 times the hazard ratio compared to no chronic disease, respectively. Laminitis was involved in 74% of cases of multimorbidity. The population of horses attended by UK veterinarians appears to be aging, and chronic diseases and their co-occurrence are common features, and as such warrant further investigation. PMID:27544263

  11. Smoking Initiation, Tobacco Product Use, and Secondhand Smoke Exposure Among General Population and Sexual Minority Youth, Missouri, 2011–2012

    PubMed Central

    McElroy, Jane A.; Everett, Kevin D.

    2014-01-01

    Introduction Research indicates disparities in risky health behaviors between heterosexual and sexual minority (referred to as LGBQ; also known as lesbian, gay, bisexual, queer, and questioning) youth. Limited data are available for tobacco-use–related behaviors beyond smoking status. We compared data on tobacco age of initiation, product use, and secondhand smoke exposure between general population and LGBQ youth. Methods Data for general population youth were from the statewide, representative 2011 Missouri Youth Tobacco Survey, and data for LGBQ youth were from the 2012 Out, Proud and Healthy survey (collected at Missouri Pride Festivals). Age-adjusted Cochran-Mantel-Haenszel tests were used to examine differences between general population (N = 1,547) and LGBQ (N = 410) youth, aged 14 to 18 years. Logistic regression models identified variables associated with current smoking. Results The 2 groups differed significantly on many tobacco-use–related factors. General population youth initiated smoking at a younger age, and LGBQ youth did not catch up in smoking initiation until age 15 or 16. LGBQ youth (41.0%) soon surpassed general population youth (11.2%) in initiation and proportion of current smokers. LGBQ youth were more likely to use cigars/cigarillos, be poly-tobacco users, and be exposed to secondhand smoke (SHS) in a vehicle (for never smokers). Older age (odds ratio [OR] = 1.39, 95% confidence interval [95% CI] = 1.18–1.62), female sex (OR = 1.64, 95% CI = 1.13–2.37), LGBQ identity (OR = 3.86, 95% CI = 2.50–5.94), other tobacco product use (OR = 8.67, 95% CI = 6.01–12.51), and SHS exposure in a vehicle (OR = 5.97, 95% CI = 3.83–9.31) all significantly increased the odds of being a current smoker. Conclusion This study highlights a need for the collection of data on sexual orientation on youth tobacco surveys to address health disparities among LGBQ youth. PMID:24995655

  12. Body mass index and blood glucose in psychiatric and general practice populations.

    PubMed

    McAvoy, Sarah; Cordiner, Matthew; Kelly, Jackie; Chiwanda, Laura; Jefferies, Christine; Miller, Kirsteen; Shajahan, Polash

    2016-06-01

    Aims and method Using a retrospective observational approach, we aimed to discern whether there was a difference in metabolic parameters between psychiatric and general practice populations in the same locality. Second, we aimed to establish differences in metabolic parameters of patients taking olanzapine, clozapine or aripiprazole. Results Patients with psychiatric illness had a body mass index (BMI) comparable to that of the general practice population (28.7 v. 29.7 kg/m(2)), but blood glucose was significantly lower in the general practice population (4.8 v. 6.1 mmol/L). Olanzapine was associated with the lowest BMI (26.1 kg/m(2)) and aripiprazole the highest (32.2 kg/m(2)), with no difference in blood glucose between antipsychotics. Clinical implications Awareness of environmental factors and how they affect individuals is important and medications are not the only cause of metabolic effects. There may be a channelling bias present, meaning practitioners are cognisant of potential metabolic effects prior to prescribing. Overall monitoring of physical health is important regardless of potential cause. PMID:27280032

  13. Body mass index and blood glucose in psychiatric and general practice populations

    PubMed Central

    McAvoy, Sarah; Cordiner, Matthew; Kelly, Jackie; Chiwanda, Laura; Jefferies, Christine; Miller, Kirsteen; Shajahan, Polash

    2016-01-01

    Aims and method Using a retrospective observational approach, we aimed to discern whether there was a difference in metabolic parameters between psychiatric and general practice populations in the same locality. Second, we aimed to establish differences in metabolic parameters of patients taking olanzapine, clozapine or aripiprazole. Results Patients with psychiatric illness had a body mass index (BMI) comparable to that of the general practice population (28.7 v. 29.7 kg/m2), but blood glucose was significantly lower in the general practice population (4.8 v. 6.1 mmol/L). Olanzapine was associated with the lowest BMI (26.1 kg/m2) and aripiprazole the highest (32.2 kg/m2), with no difference in blood glucose between antipsychotics. Clinical implications Awareness of environmental factors and how they affect individuals is important and medications are not the only cause of metabolic effects. There may be a channelling bias present, meaning practitioners are cognisant of potential metabolic effects prior to prescribing. Overall monitoring of physical health is important regardless of potential cause. PMID:27280032

  14. A novel biomarker panel for irritable bowel syndrome and the application in the general population.

    PubMed

    Mujagic, Zlatan; Tigchelaar, Ettje F; Zhernakova, Alexandra; Ludwig, Thomas; Ramiro-Garcia, Javier; Baranska, Agnieszka; Swertz, Morris A; Masclee, Ad A M; Wijmenga, Cisca; van Schooten, Frederik J; Smolinska, Agnieszka; Jonkers, Daisy M A E

    2016-01-01

    Biological markers that measure gut health and diagnose functional gastro-intestinal (GI) disorders, such as irritable bowel syndrome (IBS), are lacking. The objective was to identify and validate a biomarker panel associated with the pathophysiology of IBS that discriminates IBS from healthy controls (HC), and correlates with GI symptom severity. In a case-control design, various plasma and fecal markers were measured in a cohort of 196 clinical IBS patients and 160 HC without GI symptoms. A combination of biomarkers, which best discriminates between IBS and HC was identified and validated in an independent internal validation set and by permutation testing. The correlation between the biomarker panel and GI symptom severity was tested in IBS patients and in a general population cohort of 958 subjects. A set of 8 biomarker panel was identified to discriminate IBS from HC with high sensitivity (88.1%) and specificity (86.5%). The results for the IBS subtypes were comparable. Moreover, a moderate correlation was found between the biomarker panel and GI symptom scores in the IBS (r = 0.59, p < 0.001) and the general population cohorts (r = 0.51, p = 0.003). A novel multi-domain biomarker panel has been identified and validated, which correlated moderately to GI symptom severity in IBS and general population subjects. PMID:27263852

  15. A novel biomarker panel for irritable bowel syndrome and the application in the general population

    PubMed Central

    Mujagic, Zlatan; Tigchelaar, Ettje F.; Zhernakova, Alexandra; Ludwig, Thomas; Ramiro-Garcia, Javier; Baranska, Agnieszka; Swertz, Morris A.; Masclee, Ad A. M.; Wijmenga, Cisca; van Schooten, Frederik J.; Smolinska, Agnieszka; Jonkers, Daisy M. A. E.

    2016-01-01

    Biological markers that measure gut health and diagnose functional gastro-intestinal (GI) disorders, such as irritable bowel syndrome (IBS), are lacking. The objective was to identify and validate a biomarker panel associated with the pathophysiology of IBS that discriminates IBS from healthy controls (HC), and correlates with GI symptom severity. In a case-control design, various plasma and fecal markers were measured in a cohort of 196 clinical IBS patients and 160 HC without GI symptoms. A combination of biomarkers, which best discriminates between IBS and HC was identified and validated in an independent internal validation set and by permutation testing. The correlation between the biomarker panel and GI symptom severity was tested in IBS patients and in a general population cohort of 958 subjects. A set of 8 biomarker panel was identified to discriminate IBS from HC with high sensitivity (88.1%) and specificity (86.5%). The results for the IBS subtypes were comparable. Moreover, a moderate correlation was found between the biomarker panel and GI symptom scores in the IBS (r = 0.59, p < 0.001) and the general population cohorts (r = 0.51, p = 0.003). A novel multi-domain biomarker panel has been identified and validated, which correlated moderately to GI symptom severity in IBS and general population subjects. PMID:27263852

  16. Explanations of sleep paralysis among Egyptian college students and the general population in Egypt and Denmark.

    PubMed

    Jalal, Baland; Simons-Rudolph, Joseph; Jalal, Bamo; Hinton, Devon E

    2014-04-01

    This cross-cultural study compared explanations of sleep paralysis (SP) in two countries and two groups with different levels of education in one country. Comparisons were made between individuals having experienced SP at least once in a lifetime from Cairo, Egypt (n = 89), Copenhagen, Denmark (n = 59), and the American University in Cairo, Egypt (n = 44). As hypothesized, participants from the general Egyptian population were more likely to endorse supernatural causal explanation of their SP compared to participants from Denmark; participants from the American University in Cairo were less likely to endorse supernatural causes of their SP compared to participants from the general Egyptian population. Moreover, participants from the American University in Cairo were marginally significantly more likely to endorse supernatural causes of their SP compared to participants from Denmark. Additionally, we explored which culturally bound explanations and beliefs about SP existed in Egypt and Denmark. We found that nearly half (48%) of the participants from the general Egyptian population believed their SP to be caused by the Jinn, a spirit-like creature with roots in Islamic tradition, which constitutes a culturally bound interpretation of the phenomenology of SP in this region of the world. Case studies are presented to illustrate these findings. PMID:24084761

  17. Sustainable leprosy related disability care within integrated general health services: findings from Salem District, India.

    PubMed

    Madhavan, K; Vijayakumaran, P; Ramachandran, L; Manickam, C; Rajmohan, R; Mathew, Jacob; Krishnamurthy, P

    2007-12-01

    The main focus of leprosy control has been case detection and treatment delivery with relative neglect of prevention of disability. Absence of reliable data and lack of research have added to the problem. This raised concerns about the capacity of the general health system to address the needs of people living with leprosy-related disabilities. In this prospective study appropriate services for people living with leprosy-related disabilities were introduced in the form of self-care training, guidance and monitoring by the general health staff facilitated by a non-governmental organisation leprosy centre in a district in south India with a population of 3.1 million (estimated in 2005). The staff identified 1232 people with leprosy-related disabilities and trained them in self-care. Follow-up assessments indicated that 86% were found to be practising self-care regularly and all the 239 general health workers were found to be actively involved. The most heartening outcome was the healing of plantar ulcers in 70% of people at the 1-year follow up. This intervention is sustainable because of the simplicity of the procedures and the involvement of all health staff including supervisors. PMID:18309709

  18. Probing General Relativity and New Physics with Lunar Laser Ranging

    NASA Astrophysics Data System (ADS)

    Dell'Agnello, S.; Maiello, M.; Currie, D. G.; Boni, A.; Berardi, S.; Cantone, C.; Delle Monache, G. O.; Intaglietta, N.; Lops, C.; Garattini, M.; Martini, M.; Patrizi, G.; Porcelli, L.; Tibuzzi, M.; Vittori, R.; Bianco, G.; Coradini, A.; Dionisio, C.; March, R.; Bellettini, G.; Tauraso, R.; Chandler, J.

    2012-11-01

    Over the past 40 years, Lunar Laser Ranging (LLR, developed by the Univ. of Maryland (PI) and INFN-LNF (Co-PI)) to the Apollo Cube Corner Retroreflector (CCR) arrays have supplied almost all the significant tests of General Relativity (Currie et al., 2009 [12]). LLR can evaluate the PPN (Post Newtonian Parameters), addressing this way both the possible changes in the gravitational constant and the self-energy properties of the gravitational field. In addition, the LLR has provided significant information on the composition and origin of the Moon. This is the only Apollo experiment that is still in operation. Initially the Apollo LLR arrays contributed a negligible fraction of the ranging error budget. Over the decades, the ranging capabilities of the ground stations have improved by more than two orders of magnitude. Now, because of the lunar librations, the existing Apollo retroreflector arrays contribute a significant fraction of the limiting errors in the range measurements. We built a new experimental apparatus (the ‘Satellite/Lunar Laser Ranging Characterization Facility', SCF) and created a new test procedure (the SCF-Test) to characterize and model the detailed thermal behavior and the optical performance of cube corner laser retroreflectors in space for industrial and scientific applications (Dell'Agnello et al., 2011 [13]). Our key experimental innovation is the concurrent measurement and modeling of the optical Far Field Diffraction Pattern (FFDP) and the temperature distribution of the SLR retroreflector payload under thermal conditions produced with a close-match solar simulator. The apparatus includes infrared cameras for non-invasive thermometry, thermal control and real-time movement of the payload to experimentally simulate satellite orientation on orbit with respect to both solar illumination and laser interrogation beams. These unique capabilities provide experimental validation of the space segment for SLR and Lunar Laser Ranging (LLR). The

  19. Probing modifications of general relativity using current cosmological observations

    SciTech Connect

    Zhao Gongbo; Bacon, David J.; Koyama, Kazuya; Nichol, Robert C.; Song, Yong-Seon; Giannantonio, Tommaso; Pogosian, Levon; Silvestri, Alessandra

    2010-05-15

    We test general relativity (GR) using current cosmological data: the CMB from WMAP5 [E. Komatsu et al. (WMAP Collaboration), Astrophys. J. Suppl. Ser. 180, 330 (2009)], the integrated Sachs-Wolfe (ISW) effect from the cross correlation of the CMB with six galaxy catalogs [T. Giannantonio et al., Phys. Rev. D 77, 123520 (2008)], a compilation of supernovae (SNe) type Ia including the latest Sloan Digital Sky Survey SNe [R. Kessler et al., Astrophys. J. Suppl. Ser. 185, 32 (2009).], and part of the weak lensing (WL) data from the Canada-Franco-Hawaii Telescope Legacy Survey [L. Fu et al., Astron. Astrophys. 479, 9 (2008); M. Kilbinger et al., Astron. Astrophys. 497, 677 (2009).] that probe linear and mildly nonlinear scales. We first test a model in which the effective Newtonian constant {mu} and the ratio of the two gravitational potentials, {eta}, transit from the GR value to another constant at late times; in this case, we find that GR is fully consistent with the combined data. The strongest constraint comes from the ISW effect which would arise from this gravitational transition; the observed ISW signal imposes a tight constraint on a combination of {mu} and {eta} that characterizes the lensing potential. Next, we consider four pixels in time and space for each function {mu} and {eta}, and perform a principal component analysis, finding that seven of the resulting eight eigenmodes are consistent with GR within the errors. Only one eigenmode shows a 2{sigma} deviation from the GR prediction, which is likely to be due to a systematic effect. However, the detection of such a deviation demonstrates the power of our time- and scale-dependent principal component analysis methodology when combining observations of structure formation and expansion history to test GR.

  20. Disseminating General Relativity for 21st century astronomy

    NASA Astrophysics Data System (ADS)

    Crosta, Mariateresa

    2015-08-01

    The talk aims to present two outreach projects - initially developed for the ESA Gaia satellite, a multidisciplinary mission launched on December 19, 2013 - available to the OAD community: NeST and "The Meaning of Light".NeST is an interactive educational tool, that displays how the theory of GR rules the Universe, it creates a performance physically "belonging" to the exhibition space and moving through it, materializing what J.A. Wheeler said "mass tells space-time how to curve, and space-time tells mass how to move"."The Meaning of Light" is a short motion comics, part of an extensive outreach program called "The History of Photons" whose main theme is the story of a beam of stellar photons that, after leaving the progenitor star, propagates through the Universe and, once intercepted come into contact with a team of scientists: here begins their adventure to be taken "back" home and in doing so the scientists, and the spectators, are driven to discover the wonders of which the light are the bearers.The description of the journey of the photons becomes, therefore, an opportunity to easily tell the fascinating topics of Astrophysics and General Relativity, i.e. the complexity and the infinite beauty of the Universe in which we live.For this movie a new theme song was produced, "Singing the Stars", whose refrain (Oh Be A Fine Girl / Guy Kiss Me Little Thing, Yeah) adds to the famous mnemonic for stellar classification (OBAFGKM) the new stellar types LTY discovered in recent years.

  1. A generalized Brownian motion model for turbulent relative particle dispersion

    NASA Astrophysics Data System (ADS)

    Shivamoggi, B. K.

    2016-08-01

    There is speculation that the difficulty in obtaining an extended range with Richardson-Obukhov scaling in both laboratory experiments and numerical simulations is due to the finiteness of the flow Reynolds number Re in these situations. In this paper, a generalized Brownian motion model has been applied to describe the relative particle dispersion problem in more realistic turbulent flows and to shed some light on this issue. The fluctuating pressure forces acting on a fluid particle are taken to be a colored noise and follow a stationary process and are described by the Uhlenbeck-Ornstein model while it appears plausible to take their correlation time to have a power-law dependence on Re, thus introducing a bridge between the Lagrangian quantities and the Eulerian parameters for this problem. This ansatz is in qualitative agreement with the possibility of a connection speculated earlier by Corrsin [26] between the white-noise representation for the fluctuating pressure forces and the large-Re assumption in the Kolmogorov [4] theory for the 3D fully developed turbulence (FDT) as well as a similar argument of Monin and Yaglom [23] and a similar result of Sawford [13] and Borgas and Sawford [24]. It also provides an insight into the result that the Richardson-Obukhov scaling holds only in the infinite-Re limit and disappears otherwise. This ansatz further provides a determination of the Richardson-Obukhov constant g as a function of Re, with an asymptotic constant value in the infinite-Re limit. It is shown to lead to full agreement, in the small-Re limit as well, with the Batchelor-Townsend [27] scaling for the rate of change of the mean square interparticle separation in 3D FDT, hence validating its soundness further.

  2. Radiation reaction in binary systems in general relativity

    NASA Astrophysics Data System (ADS)

    Kennefick, Daniel John

    1997-09-01

    This thesis is concerned with current problems in, and historical aspects of, the problem of radiation reaction in stellar binary systems in general relativity. Part I addresses current issues in the orbital evolution due to gravitational radiation damping of compact binaries. A particular focus is on the inspiral of small bodies orbiting large black holes, employing a perturbation formalism. In addition, the merger, at the end of the insprial, of comparable mass compact binaries, such as neutron star binaries is also discussed. The emphasis of Part I is on providing detailed descriptions of sources and signals with a view to optimising signal analysis in gravitational wave detectors, whether ground- or space- based interferometers, or resonant mass detectors. Part II of the thesis examines the historical controversies surrounding the problem of gravitational waves, and gravitational radiation damping in stellar binaries. In particular, it focuses on debates in the mid 20th-century on whether binary star systems would really exhibit this type of damping and emit gravitational waves, and on the 'quadrupole formula controversy' of the 1970s and 1980s, on the question whether the standard formular describing energy loss due to emission of gravitational waves was correctly derived for such systems. The study shed light on the role of analogy in science, especially where its use is controversial, on the importance of style in physics and on the problem of identity in science, as the use of history as a rhetorical device in controversial debate is examined. The concept of the Theoretician's Regress is introduced to explain the difficulty encountered by relativists in closing debate in this controversy, which persisted in one forms or another for several decades.

  3. HIV in Children in a General Population Sample in East Zimbabwe: Prevalence, Causes and Effects

    PubMed Central

    Pufall, Erica L.; Nyamukapa, Constance; Eaton, Jeffrey W.; Mutsindiri, Reggie; Chawira, Godwin; Munyati, Shungu; Robertson, Laura; Gregson, Simon

    2014-01-01

    Background There are an estimated half-million children living with HIV in sub-Saharan Africa. The predominant source of infection is presumed to be perinatal mother-to-child transmission, but general population data about paediatric HIV are sparse. We characterise the epidemiology of HIV in children in sub-Saharan Africa by describing the prevalence, possible source of infection, and effects of paediatric HIV in a southern African population. Methods From 2009 to 2011, we conducted a household-based survey of 3389 children (aged 2–14 years) in Manicaland, eastern Zimbabwe (response rate: 73.5%). Data about socio-demographic correlates of HIV, risk factors for infection, and effects on child health were analysed using multi-variable logistic regression. To assess the plausibility of mother-to-child transmission, child HIV infection was linked to maternal survival and HIV status using data from a 12-year adult HIV cohort. Results HIV prevalence was (2.2%, 95% CI: 1.6–2.8%) and did not differ significantly by sex, socio-economic status, location, religion, or child age. Infected children were more likely to be underweight (19.6% versus 10.0%, p = 0.03) or stunted (39.1% versus 30.6%, p = 0.04) but did not report poorer physical or psychological ill-health. Where maternal data were available, reported mothers of 61/62 HIV-positive children were deceased or HIV-positive. Risk factors for other sources of infection were not associated with child HIV infection, including blood transfusion, vaccinations, caring for a sick relative, and sexual abuse. The observed flat age-pattern of HIV prevalence was consistent with UNAIDS estimates which assumes perinatal mother-to-child transmission, although modelled prevalence was higher than observed prevalence. Only 19/73 HIV-positive children (26.0%) were diagnosed, but, of these, 17 were on antiretroviral therapy. Conclusions Childhood HIV infection likely arises predominantly from mother-to-child transmission and is

  4. Patterns of Hamstring Muscle Tears in the General Population: A Systematic Review

    PubMed Central

    Kuske, Barbara; Hamilton, David F.; Pattle, Sam B.; Simpson, A. Hamish R. W.

    2016-01-01

    Background Hamstring tears are well recognised in the sporting population. Little is known about these injuries in the general population. Purpose Evaluating the rates, patterns and risk factors of non-sporting hamstring tears, compared to sporting related hamstring tears. Data Sources MEDLINE, EMBASE, CINAHL, and the Cochrane Central Register of Controlled Trials (1989–2015). Study Selection Studies reporting patients with a grade 2 or 3 hamstring muscle tear, identified clinically, confirmed by MRI imaging or direct visualisation during surgical exploration. Data Synthesis 144 sets of linked data were extracted for analysis. Most injuries were in males (81.3%), where mean age at injury was lower (30.2, 95% CI 29.1–31.3) than in females (35.4, 95% CI 32.4–38.4) p = 0.06. Key differences were found in the proportion of non-sporting injuries in patients under and over the age 40 (p = 0.001). The proportion of non-sporting injuries was significantly higher in females compared to males (25.9% female non-sporting injuries, versus 8.5% male; p = 0.02). Avulsions were more frequently reported in non-sporting activities (70.5%). The proportion of such injuries was notably higher in females, though this failed to meet significance (p = 0.124). Grouped by age category a bimodal distribution was noted, with the proportion of avulsions greater in younger (age <15) and older patients (age > 40) (p = 0.008). 86.8% of patients returned to pre-injury activity levels with a similar frequency across all study variables; age, activity (sporting vs non-sporting) and injury type (avulsion vs tear). Conclusion This review highlights a proportion of adults suffering grade 2 or 3 hamstring injuries from activities other than the classic sports trauma. The majority of these non-sporting injuries were avulsion injuries that clustered in older female and skeletally immature patients suggesting a potential link to bone mineral density. PMID:27144648

  5. Desphospho-uncarboxylated matrix Gla protein is associated with increased aortic stiffness in a general population.

    PubMed

    Mayer, O; Seidlerová, J; Wohlfahrt, P; Filipovský, J; Vaněk, J; Cífková, R; Windrichová, J; Topolčan, O; Knapen, M H J; Drummen, N E A; Vermeer, C

    2016-07-01

    Matrix Gla protein (MGP), a natural inhibitor of calcification, strongly correlates with the extent of coronary calcification. Vitamin K is the essential cofactor for the activation of MGP. The nonphosphorylated-uncarboxylated isoform of MGP (dp-ucMGP) reflects the status of this vitamin. We investigated whether there is an association between dp-ucMGP and stiffness of elastic and muscular-type large arteries in a random sample from the general population. In a cross-sectional design, we analyzed 1087 subjects from the Czech post-MONICA study. Aortic and femoro-popliteal pulse wave velocities (PWVs) were measured using a Sphygmocor device. Dp-ucMGP concentrations were assessed in freshly frozen samples by enzyme-linked immunosorbent assay methods using the InaKtif MGP iSYS pre-commercial kit developed by IDS and VitaK. Aortic PWV significantly (P<0.0001) increased across the dp-ucMGP quartiles. After adjustment for all potential confounders, aortic PWV independently correlated with dp-ucMGP (with beta coefficient (s.d.) 11.61 (5.38) and P-value=0.031). In a categorized manner, subjects in the top quartile of dp-ucMGP (⩾ 671 pmol l(-1)) had a higher risk of elevated aortic PWV, with corresponding adjusted odds ratio (95% confidence interval) 1.73 (1.17-2.5). In contrast, no relation between dp-ucMGP and femoro-popliteal PWV was found. In conclusion, increased dp-ucMGP, which is a circulating biomarker of vitamin K status and vascular calcification, is independently associated with aortic stiffness, but not with stiffness of distal muscular-type arteries. PMID:26016598

  6. A Search for Extreme Horizontal Branch Stars in the General Field Population (Abstract)

    NASA Astrophysics Data System (ADS)

    Walker, D.; Albrow, M.

    2014-12-01

    (Abstract only) The study of pulsating Extreme Horizontal Branch (EHB) stars in globular clusters is a new field of stellar research. The initial discovery of three rapidly pulsating EHB stars in w Centauri was announced at the Fourth Meeting on Hot Subdwarfs and Related Objects held in Shanghai in July 2009. A fourth sdB pulsator was discovered in the remaining photometry data soon afterwards; all were discovered in data obtained by the New Techology Telescope. In March 2013, the Space Telescope Imaging Spectrograph (STIS) was utilized on five consecutive orbits to obtain far-UV imagery of NGC 2808’s core, revealing six sdB pulsators with periods 85 to 149 seconds and UV amplitudes from 2.0 to 6.8%. To date (April 2014), these ten EHB pulsators in w Centauri and NGC 2808 form a unique class of EHB variable closely clustered around Teff ~ 50,000 K. This talk describes an initial candidate search for EHB rapidly pulsating sdB stars in the general galactic field population. The search was conducted with the 1-m McLellan telescope at the Mt. John University Observatory (MJUO) at Lake Tekapo, New Zealand. Observations were conducted utilizing a special high speed f/8 frame-transfer camera called the Puoko-nui. The candidate set of stars was taken from the Edinburgh-Cape Blue Object Survey based on the selection criteria of a (B-V) value of -0.32 to -0.36, corresponding to the desired temperature range Teff ranging from 40,000 to 64,000 K. The objective of this search was to determine whether smaller size telescopes could identify promising sets of candidate sdB pulsators which could be followed up with larger professional systems.

  7. Association between processing speed and subclinical psychotic symptoms in the general population: focusing on sex differences.

    PubMed

    Rössler, Wulf; Ajdacic-Gross, Vladeta; Müller, Mario; Rodgers, Stephanie; Kawohl, Wolfram; Haker, Helene; Hengartner, Michael P

    2015-08-01

    Evidence is growing that persons along the schizophrenia spectrum, i.e., those who also display subclinical psychotic symptoms, exhibit deficits across a broad range of neuropsychological domains. Because sex differences in the association between cognitive deficits and psychosis have thus far been mostly neglected, we believe that ours is the first study specifically focused upon those differences when examining the relationship between subclinical psychosis and processing speed. Using a sample of 213 persons from the general population from Zurich, Switzerland, psychotic symptoms were assessed with three different questionnaires including the Schizotypal Personality Questionnaire, an adaptation of the Structured Interview for Assessing Perceptual Anomalies, and the Paranoia Checklist. Processing speed was assessed with the WAIS digit-symbol coding test. Two higher-order psychosis domains were factor-analytically derived from the various psychosis subscales and then subjected to a series of linear regression analyses. The results demonstrate that in both men and women associations between subclinical psychosis domains and processing speed were weak to moderate (β ranging from -0.18 to -0.27; all p<0.05). However, we found no sex-differences in the interrelation of subclinical psychosis and processing speed (ΔR(2)<0.005; p>0.30). In conclusion, it appears that sex differences in psychosis manifest themselves only at the high end of the continuum (full-blown schizophrenia) and not across the sub-threshold range. The small magnitude of the effects reported herein conforms to the etiopathology of the disorder. Since schizophrenia and related disorders from the spectrum are assumed to be multifactorial diseases, it follows that many etiological components of small effect are involved. PMID:26070411

  8. Association between dietary factors and plasma fetuin-A concentrations in the general population.

    PubMed

    Nimptsch, Katharina; Janke, Jürgen; Pischon, Tobias; Linseisen, Jakob

    2015-10-28

    Circulating fetuin-A, a novel marker for hepatic fat accumulation, has been related to a higher risk of type 2 diabetes and cardiovascular diseases in a growing number of prospective studies. However, little is known about dietary determinants of fetuin-A concentrations in the general population. Therefore, we aimed to investigate the association between dietary intake of energy, energy-providing nutrients, alcohol and major food groups and plasma fetuin-A concentrations in the Bavarian Food Consumption Survey II. Dietary intake was assessed by three 24-h dietary recalls, and plasma concentrations of fetuin-A were measured in 558 adults (18-81 years). After multivariable adjustment for lifestyle factors and body fatness, higher energy intake was nonsignificantly associated with higher fetuin-A concentrations (per 2092 kJ/d (500 kcal/d) 3·7 µg/ml, 95 % CI -0·5, 7·8 µg/ml). There was no clear association between energy-providing nutrients and fetuin-A concentrations. Higher alcohol intake was associated with lower fetuin-A concentrations (P trend 0·003): mean fetuin-A concentrations were 324 (95 % CI 313, 335) µg/ml in non-drinkers, and with 293 (95 % CI 281, 306) µg/ml significantly lower in participants who drank ≥30 g alcohol per d. Mean fetuin-A concentrations decreased across quintiles of milk and dairy product intake (lowest quintile 319 (95 % CI 309, 330) µg/ml; highest quintile 304 (95 % CI 293, 314) µg/ml; P trend 0·03), and each 150-g increment in milk/dairy products per d was associated with 5·6 (95 % CI -9·6, -1·5) µg/ml lower fetuin-A. Dietary intakes of vegetables, meat or fish were not associated with fetuin-A concentrations. Because of the preventive potential of our findings, further exploration is warranted. PMID:26316198

  9. Prevalence and Risk Factors of Tinea Unguium and Tinea Pedis in the General Population in Spain

    PubMed Central

    Perea, Sofia; Ramos, Maria Jose; Garau, Margarita; Gonzalez, Alba; Noriega, Antonio R.; del Palacio, Amalia

    2000-01-01

    This study prospectively evaluated the prevalence and risk factors of tinea unguium and tinea pedis in the general adult population in Madrid, Spain. One thousand subjects were clinically examined, and samples of nails and scales from the interdigital spaces of the feet were taken from those patients presenting with signs or symptoms of onychomycosis and/or tinea pedis, respectively. In addition, a sample from the fourth interdigital space of both feet was collected from all individuals with a piece of sterilized wool carpet. Tinea unguium was defined as a positive direct examination with potassium hydroxide and culture of the etiological agent from subjects with clinically abnormal nails. Patients with positive dermatophyte cultures of foot specimens were considered to have tinea pedis. The prevalence of tinea unguium was 2.8% (4.0% for men and 1.7% for women), and the prevalence of tinea pedis was 2.9% (4.2% for men and 1.7% for women). The etiological agents of tinea unguium were identified as Trichopyton rubrum (82.1%), followed by Trichopyton mentagrophytes var. interdigitale (14.3%) and Trichopyton tonsurans (3.5%). Trichophyton rubrum (44.8%) and Trichophyton mentagrophytes (44.8%), followed by Epidermophyton floccosum (7%) and T. tonsurans (3.4%), were the organisms isolated from patients with tinea pedis. The percentage of subjects who suffered simultaneously from both diseases was 1.1% (1.7% for men and 0.6% for women). In a multivariate logistic regression analysis, age (relative risk [RR], 1.03) and gender (RR, 2.50) were independent risk factors for tinea unguium, while only gender (RR, 2.65) was predictive for the occurrence of tinea pedis. In both analyses, the presence of one of the two conditions was associated with a higher risk for the appearance of the other disease (RR, >25). PMID:10970362

  10. Cadmium exposure and risk of prostate cancer: a meta-analysis of cohort and case-control studies among the general and occupational populations

    PubMed Central

    Chen, Cheng; Xun, Pengcheng; Nishijo, Muneko; Carter, Sue; He, Ka

    2016-01-01

    We aimed to evaluate the association of cadmium exposure with the risk of prostate cancer in both the general and occupational populations. Online database searches were performed for studies of prostate cancer risk and cadmium exposure. Twelve cohort studies (5 in the general, 7 in occupational populations) and 9 case-control studies (3 in the general, 6 in occupational populations) were identified. Five/seven cohort studies in the general and occupational populations consist of 78,263/13, 434 participants with a mean follow-up of 12.1/43.0 years, respectively. Case-control studies include 334 cases/670 controls in the general population, and 1,315 cases/4,477 controls in occupational populations. Comparing the highest to the lowest category of cadmium exposure in the general population, the weighted relative risk of prostate cancer incidence and mortality among cohort studies, and the weighted odds ratio in case-control studies were 1.05 (95%CI [0.91, 1.22]), 0.83 (95%CI [0.35, 1.98]), and 1.27 (95%CI [0.58,2.78]), respectively. For occupational populations, the weighted OR in case-control studies was 1.17 (95%CI [0.85, 1.62]), and the weighted standardized mortality ratio in cohort studies was 98 (95%CI [75, 126]). Accumulated epidemiological evidence does not support the hypothesis that cadmium exposure may increase the risk of prostate cancer in either the general or occupational populations. PMID:27174617

  11. Testing for Ancient Admixture between Closely Related Populations

    PubMed Central

    Durand, Eric Y.; Patterson, Nick; Reich, David; Slatkin, Montgomery

    2011-01-01

    One enduring question in evolutionary biology is the extent of archaic admixture in the genomes of present-day populations. In this paper, we present a test for ancient admixture that exploits the asymmetry in the frequencies of the two nonconcordant gene trees in a three-population tree. This test was first applied to detect interbreeding between Neandertals and modern humans. We derive the analytic expectation of a test statistic, called the D statistic, which is sensitive to asymmetry under alternative demographic scenarios. We show that the D statistic is insensitive to some demographic assumptions such as ancestral population sizes and requires only the assumption that the ancestral populations were randomly mating. An important aspect of D statistics is that they can be used to detect archaic admixture even when no archaic sample is available. We explore the effect of sequencing error on the false-positive rate of the test for admixture, and we show how to estimate the proportion of archaic ancestry in the genomes of present-day populations. We also investigate a model of subdivision in ancestral populations that can result in D statistics that indicate recent admixture. PMID:21325092

  12. Provocation of nonepileptic seizures by suggestion in a general seizure population.

    PubMed

    Bazil, C W; Kothari, M; Luciano, D; Moroney, J; Song, S; Vasquez, B; Weinreb, H J; Devinsky, O

    1994-01-01

    Nonepileptic seizures (NES) are common and are often diagnosed at epilepsy centers by video-EEG recording of both spontaneous and suggestion-induced episodes, but no study has evaluated provocative testing in a general seizure population. We studied consecutive patients with a tentative diagnosis of epilepsy using saline provocation during video-EEG recording, suggesting that this could produce a typical seizure. Of 52 patients, 40% had no response, 23% had responses unlike their seizures, and 37% had typical episodes (positive test). Patients whose usual episodes resembled complex partial seizures (CPS) were more likely to have NES than were patients with a history of generalized tonic-clonic seizures (GTC). Of patients with positive provocations, the primary physician predicted NES in 68% of cases. This preliminary study suggests that NES are frequent in a general neurology setting, and that saline provocation is a sensitive method of identifying NES. PMID:8082620

  13. Physical activity in adolescents with psychiatric disorders and in the general population

    PubMed Central

    2014-01-01

    Background Adults who suffer from psychiatric disorders report low levels of physical activity and the activity levels differ between disorders. Less is known regarding physical activity across psychiatric disorders in adolescence. We investigate the frequency and type of physical activity in adolescent psychiatric patients, compared with adolescents in the general population. Methods A total of 566 adolescent psychiatric patients aged 13–18 years who participated in the CAP survey, Norway, were compared to 8173 adolescents aged 13–19 years who participated in the Nord-Trøndelag Health Study, Young-HUNT 3, Norway. All adolescents completed a questionnaire, including questions about physical activity and participation in team and individual sports. Results Approximately 50% of adolescents with psychiatric disorders and 25% of the population sample reported low levels of physical activity. Within the clinical sample, those with mood disorders (62%) and autism spectrum disorders (56%) were the most inactive and those with eating disorders (36%) the most active. This pattern was the same in individual and team sports. After multivariable adjustment, adolescents with a psychiatric disorder had a three-fold increased risk of lower levels of physical activity, and a corresponding risk of not participating in team and individual sports compared with adolescents in the general population. Conclusions Levels of physical activity were low in adolescent psychiatric patients compared with the general population, yet activity levels differed considerably between various disorders. The findings underscore the importance of assessing physical activity in adolescents with psychiatric disorders and providing early intervention to promote mental as well as physical health in this early stage of life. PMID:24450542

  14. Some Effects of Spacetime Curvature in General Relativity

    NASA Astrophysics Data System (ADS)

    McClune, James Cephas

    clearer physical interpretation and further extends the interpretation of the Bel-Robinson tensor by identifying other elements of this tensor as the gravitational analog of Maxwell stresses. I have calculated the Bel-Robinson tensor for a class of gravitational wave spacetimes using GRTensorII in Maple. In this way, I have identified the Poynting vector and the pressure of this radiation field. The Bel-Robinson tensor is a curvature-squared object, the further study of which may give insight into how energy is transferred by curved spacetime. done previously by B. Mashhoon and H. Quevedo, who invented RGWs as extensions of Beck-Einstein-Rosen waves. I have contributed to this work by generating numerical solutions to certain field equations in a search for further analytic solutions, and I have also used Computer Algebra Systems for the analytic calculation of various objects related to the RGW metric. The computer work has led us to believe that the single analytic solution presented by B. Mashhoon and H. Quevedo is the only pure gravitational wave solution which exists within this class of RGW metrics. I have calculated the Bel-Robinson tensor for this metric in the coordinate basis used by Mashhoon and Quevedo. Furthermore, I have calculated certain components of the stress-energy tensor for the general rotating gravitational wave solution in a tetrad basis, since, in the light of the above new derivation, the Bel-Robinson tensor is best interpreted in terms of an orthonormal tetrad frame.

  15. The self-reported health of U.S. flight attendants compared to the general population

    PubMed Central

    2014-01-01

    Background Few studies have examined the broad health effects of occupational exposures in flight attendants apart from disease-specific morbidity and mortality studies. We describe the health status of flight attendants and compare it to the U.S. population. In addition, we explore whether the prevalence of major health conditions in flight attendants is associated with length of exposure to the aircraft environment using job tenure as a proxy. Methods We surveyed flight attendants from two domestic U.S. airlines in 2007 and compared the prevalence of their health conditions to contemporaneous cohorts in the National Health and Nutrition Survey (NHANES), 2005-2006 and 2007-2008. We weighted the prevalence of flight attendant conditions to match the age distribution in the NHANES and compared the two populations stratified by gender using the Standardized Prevalence Ratio (SPR). For leading health conditions in flight attendants, we analyzed the association between job tenure and health outcomes in logistic regression models. Results Compared to the NHANES population (n =5,713), flight attendants (n = 4,011) had about a 3-fold increase in the age-adjusted prevalence of chronic bronchitis despite considerably lower levels of smoking. In addition, the prevalence of cardiac disease in female flight attendants was 3.5 times greater than the general population while their prevalence of hypertension and being overweight was significantly lower. Flight attendants reported 2 to 5.7 times more sleep disorders, depression, and fatigue, than the general population. Female flight attendants reported 34% more reproductive cancers. Health conditions that increased with longer job tenure as a flight attendant were chronic bronchitis, heart disease in females, skin cancer, hearing loss, depression and anxiety, even after adjusting for age, gender, body mass index (BMI), education, and smoking. Conclusions This study found higher rates of specific diseases in flight attendants

  16. BOOK REVIEW: A First Course in General Relativity (Second Edition) A First Course in General Relativity (Second Edition)

    NASA Astrophysics Data System (ADS)

    Poisson, Eric

    2010-05-01

    A few years ago, in my review of Sean Carroll's book in Classical and Quantum Gravity [1], I wrote that while the 1970s was the decade of Weinberg [2] and Misner, Thorne and Wheeler [3], and while the eighties was the decade of Schutz [4] and Wald [5], the 2000s was clearly the decade of Hartle [6] and Carroll [7]. In my opinion, these books continue to stand out in the surprisingly dense crowd of introductory textbooks on general relativity. At the dawn of this new decade I look forward to see what fresh pedagogical insights will be produced next, and who will be revealed as the winners of the 2010s. It is, of course, much too early to tell, but Schutz is back, and he will set the standard just as he did back in 1985. This is the long-awaited second edition of his `First Course', a short, accessible, and very successful introduction to general relativity. The changes from the first edition are modest: Schutz wisely refrained from bloating the text with new topics, and limited himself to updating his discussion of gravitational-wave sources and detectors, neutron-star and black-hole astrophysics, and suggestions for further reading. Most importantly, he completely rewrote the chapter on cosmology, a topic that has evolved enormously since the first edition. The book begins in chapter 1 with a beautiful review of special relativity that emphasizes spacetime geometry and stays away from an algebraic approach based on the Lorentz transformation, which appears only later in the chapter. This is followed up in chapters 2 and 3 with an introduction to vector and tensor analysis in flat spacetime. The point of view is modern (tensors are defined as linear mapping of vectors and one-forms into real numbers) but the presentation is very accessible and avoids an overload of mathematical fine print. In chapter 4 the book introduces the spacetime description of fluids; it is here that the energy-momentum tensor makes its first appearance. The move to curved spacetime is

  17. Plasma vitamins A, C and E in the general population of Singapore, 1993 to 1995.

    PubMed

    Hughes, K; New, A L; Lee, B L; Ong, C N

    1998-03-01

    The National University of Singapore Heart Study measured cardiovascular risk factors, including selected plasma vitamins, on a random sample of the general population aged 30 to 69 years. Plasma vitamins A and E were normal and similar by ethnic group. Mean plasma vitamin A levels were: Chinese (males 0.68 and females 0.52 mg/L), Malays (males 0.67 and females 0.54 mg/L), and Indians (males 0.66 and females 0.51 mg/L). Mean plasma vitamin E levels were: Chinese (males 12.6 and females 12.6 mg/L), Malays (males 13.6 and females 13.3 mg/L), and Indians (males 12.9 and females 12.8 mg/L). No person had plasma vitamin A deficiency (< 0.01 mg/L) and only 0.1% had vitamin E deficiency (< 5.0 mg/L). In contrast, plasma vitamin C was on the low side and higher in Chinese than Malays and Indians. Mean plasma vitamin C levels were: Chinese (males 6.3 and females 8.4 mg/L), Malays (males 5.1 and females 6.4 mg/L), and Indians (males 5.7 and females 6.9 mg/L). Likewise, the proportions with plasma vitamin C deficiency (< 2.0 mg/L) were lower in Chinese (males 14.4 and females 0.7%), than Malays (males 19.7 and females 7.2%), and Indians (males 17.8 and females 11.0%). Relatively low levels of plasma vitamin C may contribute to the high rates of coronary heart disease and cancer in Singapore. In particular, lower plasma vitamin C in Malays and Indians than Chinese may contribute to their higher rates of coronary heart disease. However, plasma vitamin C does not seem to be involved in the higher rates of cancer in Chinese than Malays and Indians. The findings suggest a relatively low intake of fresh fruits and a higher intake is recommended. Also, food sources of vitamin C may be destroyed by the high cooking temperatures of local cuisines, especially the Malay and Indian ones. PMID:9663300

  18. Metabolome in schizophrenia and other psychotic disorders: a general population-based study

    PubMed Central

    2011-01-01

    Background Persons with schizophrenia and other psychotic disorders have a high prevalence of obesity, impaired glucose tolerance, and lipid abnormalities, particularly hypertriglyceridemia and low high-density lipoprotein. More detailed molecular information on the metabolic abnormalities may reveal clues about the pathophysiology of these changes, as well as about disease specificity. Methods We applied comprehensive metabolomics in serum samples from a general population-based study in Finland. The study included all persons with DSM-IV primary psychotic disorder (schizophrenia, n = 45; other non-affective psychosis (ONAP), n = 57; affective psychosis, n = 37) and controls matched by age, sex, and region of residence. Two analytical platforms for metabolomics were applied to all serum samples: a global lipidomics platform based on ultra-performance liquid chromatography coupled to mass spectrometry, which covers molecular lipids such as phospholipids and neutral lipids; and a platform for small polar metabolites based on two-dimensional gas chromatography coupled to time-of-flight mass spectrometry (GC × GC-TOFMS). Results Compared with their matched controls, persons with schizophrenia had significantly higher metabolite levels in six lipid clusters containing mainly saturated triglycerides, and in two small-molecule clusters containing, among other metabolites, (1) branched chain amino acids, phenylalanine and tyrosine, and (2) proline, glutamic, lactic and pyruvic acids. Among these, serum glutamic acid was elevated in all psychoses (P = 0.0020) compared to controls, while proline upregulation (P = 0.000023) was specific to schizophrenia. After adjusting for medication and metabolic comorbidity in linear mixed models, schizophrenia remained independently associated with higher levels in seven of these eight clusters (P < 0.05 in each cluster). The metabolic abnormalities were less pronounced in persons with ONAP or affective psychosis. Conclusions Our

  19. Consumption in relation to population, environment and development.

    PubMed

    Myers, N

    1997-01-01

    Consumption is defined as the total spending on goods, investments, and services that changes materials and energy and reduces availability of natural resources for the future. The rich consume on a grand scale, but marginal consumption by large numbers of poor people can also deplete nonrenewable resources. This article discusses the complex relationships between consumption and population and between these two factors and environment and development. Consumption of natural resources since the mid-1900s has surpassed consumption prior to that time. The richest 20% of the global population have doubled their per capita consumption of energy, meat, timber, steel, and copper and have quadrupled the number of cars owned since 1950. The poorest 20% barely increased their per capita consumption. 40% of the total world population accounts for 6.5% of the world's income. The US, with under 5% of world population, consumes about 30% of the resources. The US standard of consumption is the desired ideal in many countries, but this standard is not justified. A low projected global population of 6 billion population would increase consumption by 8.4 times. Food and energy examples are used to illustrate the resource impact. Policy must move toward sustainable consumption and meet needs differently, develop environmentally friendly goods and services, and change the nature and extent of consumption. Policy must internalize externalities, eliminate perverse subsidies, calculate the ecological impact, promote efficiency and sufficiency, mobilize the media, and set "best practices" examples. Science also has responsibilities. The future rests with decisions about how to design a better system or a default option until failures in ecological and social systems appear. Life styles should emphasize nonmaterial satisfactions. The ratio of poor to rich is 60:1, which is unacceptable. Rich citizens will eventually need to pay the price of a change in their philosophies. PMID:12321341

  20. A Student's Manual for A First Course in General Relativity

    NASA Astrophysics Data System (ADS)

    Scott, Robert B.

    2016-01-01

    Preface; 1. Special relativity; 2. Vector analysis in special relativity; 3. Tensor analysis in special relativity; 4. Perfect fluids in special relativity; 5. Preface to curvature; 6. Curved manifolds; 7. Physics in curved spacetime; 8. The Einstein field equations; 9. Gravitational radiation; 10. Spherical solutions for stars; 11. Schwarzschild geometry and black holes; 12. Cosmology; Appendix A. Acronyms and definitions; Appendix B. Useful results; References; Index.

  1. Regional block versus general anaesthesia for caesarean section and neonatal outcomes: a population-based study

    PubMed Central

    Algert, Charles S; Bowen, Jennifer R; Giles, Warwick B; Knoblanche, Greg E; Lain, Samantha J; Roberts, Christine L

    2009-01-01

    Background Anaesthesia guidelines recommend regional anaesthesia for most caesarean sections due to the risk of failed intubation and aspiration with general anaesthesia. However, general anaesthesia is considered to be safe for the foetus, based on limited evidence, and is still used for caesarean sections. Methods Cohorts of caesarean sections by indication (that is, planned repeat caesarean section, failure to progress, foetal distress) were selected from the period 1998 to 2004 (N = 50,806). Deliveries performed under general anaesthesia were compared with those performed under spinal or epidural, for the outcomes of neonatal intubation and 5-minute Apgar (Apgar5) <7. Results The risk of adverse outcomes was increased for caesarean sections under general anaesthesia for all three indications and across all levels of hospital. The relative risks were largest for low-risk planned repeat caesarean deliveries: resuscitation with intubation relative risk was 12.8 (95% confidence interval 7.6, 21.7), and Apgar5 <7 relative risk was 13.4 (95% confidence interval 9.2, 19.4). The largest absolute increase in risk was for unplanned caesareans due to foetal distress: there were five extra intubations per 100 deliveries and six extra Apgar5 <7 per 100 deliveries. Conclusion The infants most affected by general anaesthesia were those already compromised in utero, as evidenced by foetal distress. The increased rate of adverse neonatal outcomes should be weighed up when general anaesthesia is under consideration. PMID:19402884

  2. BOOK REVIEW Exact Space-Times in Einstein's General Relativity Exact Space-Times in Einstein's General Relativity

    NASA Astrophysics Data System (ADS)

    Lake, Kayll

    2010-12-01

    , Hoenselaers C and Herlt E 2003 Exact Solutions of Einstein's Field Equations (Second Edition) (Cambridge: Cambridge University Press) [2] Pretorius F and Israel W 1998 Class. Quantum Grav.15 2289 [3] Wiltshire D, Visser M and Scott S (ed) 2008 The Kerr Spacetime: Rotating Black Holes in General Relativity (Cambridge: Cambridge University Press) [4] Coley A, Hervik S and Pelavas N 2009 Class. Quantum Grav. 26 025013 [5] Plebański J and Krasiński A 2006 An Introduction to General Relativity and Cosmology (Cambridge: Cambridge University Press)

  3. A Generalized Approach for Estimating Effective Population Size from Temporal Changes in Allele Frequency

    PubMed Central

    Waples, R. S.

    1989-01-01

    The temporal method for estimating effective population size (N(e)) from the standardized variance in allele frequency change (F) is presented in a generalized form. Whereas previous treatments of this method have adopted rather limiting assumptions, the present analysis shows that the temporal method is generally applicable to a wide variety of organisms. Use of a revised model of gene sampling permits a more generalized interpretation of N(e) than that used by some other authors studying this method. It is shown that two sampling plans (individuals for genetic analysis taken before or after reproduction) whose differences have been stressed by previous authors can be treated in a uniform way. Computer simulations using a wide variety of initial conditions show that different formulas for computing F have much less effect on N(e) than do sample size (S), number of generations between samples (t), or the number of loci studied (L). Simulation results also indicate that (1) bias of F is small unless alleles with very low frequency are used; (2) precision is typically increased by about the same amount with a doubling of S, t, or L; (3) confidence intervals for N(e) computed using a χ(2) approximation are accurate and unbiased under most conditions; (4) the temporal method is best suited for use with organisms having high juvenile mortality and, perhaps, a limited effective population size. PMID:2731727

  4. Incidence of symptomatic femoroacetabular impingement in the general population: a prospective registration study

    PubMed Central

    Röling, Maarten A.; Mathijssen, Nina M.C.; Bloem, Rolf M.

    2016-01-01

    Groin pain is a frequent cause of discomfort in patients and highly prevalent in active patients. One of the diagnoses causing groin pain is femoroacetabular impingement (FAI). However, the incidence of FAI in the general population is unknown. This study aimed to identify the incidence of groin pain suggestive of FAI in a cohort of 31 451 patients in the Netherlands during 1 year. A cooperation of 16 general practitioners (GPs) participated in this prospective registry. All GPs were educated in the clinical manifestation of FAI and the physical examination for FAI. Patients of all ages were registered when presenting with ‘groin pain’. Between July 2013 and July 2014, 84 patients aged between 15 and 60 years of age presented with groin pain, reflecting an incidence of 0.44%. Of these patients, 17% (14 patients) were radiologically diagnosed with FAI. Another 30% of these patients had a high clinical suspicion for FAI. This is the first report on the incidence of groin pain suggestive of FAI in a general population diagnosed by GPs. Of all 84 patients presenting with groin pain, 17% were diagnosed with FAI. Creating awareness of FAI in GPs helps identifying patients that might benefit from FAI treatment. PMID:27583159

  5. Clustering of health behaviours in adult survivors of childhood cancer and the general population

    PubMed Central

    Rebholz, C E; Rueegg, C S; Michel, G; Ammann, R A; von der Weid, N X; Kuehni, C E; Spycher, B D

    2012-01-01

    Background: Little is known about engagement in multiple health behaviours in childhood cancer survivors. Methods: Using latent class analysis, we identified health behaviour patterns in 835 adult survivors of childhood cancer (age 20–35 years) and 1670 age- and sex-matched controls from the general population. Behaviour groups were determined from replies to questions on smoking, drinking, cannabis use, sporting activities, diet, sun protection and skin examination. Results: The model identified four health behaviour patterns: ‘risk-avoidance', with a generally healthy behaviour; ‘moderate drinking', with higher levels of sporting activities, but moderate alcohol-consumption; ‘risk-taking', engaging in several risk behaviours; and ‘smoking', smoking but not drinking. Similar proportions of survivors and controls fell into the ‘risk-avoiding' (42% vs 44%) and the ‘risk-taking' cluster (14% vs 12%), but more survivors were in the ‘moderate drinking' (39% vs 28%) and fewer in the ‘smoking' cluster (5% vs 16%). Determinants of health behaviour clusters were gender, migration background, income and therapy. Conclusion: A comparable proportion of childhood cancer survivors as in the general population engage in multiple health-compromising behaviours. Because of increased vulnerability of survivors, multiple risk behaviours should be addressed in targeted health interventions. PMID:22722311

  6. Incidence of symptomatic femoroacetabular impingement in the general population: a prospective registration study.

    PubMed

    Röling, Maarten A; Mathijssen, Nina M C; Bloem, Rolf M

    2016-08-01

    Groin pain is a frequent cause of discomfort in patients and highly prevalent in active patients. One of the diagnoses causing groin pain is femoroacetabular impingement (FAI). However, the incidence of FAI in the general population is unknown. This study aimed to identify the incidence of groin pain suggestive of FAI in a cohort of 31 451 patients in the Netherlands during 1 year. A cooperation of 16 general practitioners (GPs) participated in this prospective registry. All GPs were educated in the clinical manifestation of FAI and the physical examination for FAI. Patients of all ages were registered when presenting with 'groin pain'. Between July 2013 and July 2014, 84 patients aged between 15 and 60 years of age presented with groin pain, reflecting an incidence of 0.44%. Of these patients, 17% (14 patients) were radiologically diagnosed with FAI. Another 30% of these patients had a high clinical suspicion for FAI. This is the first report on the incidence of groin pain suggestive of FAI in a general population diagnosed by GPs. Of all 84 patients presenting with groin pain, 17% were diagnosed with FAI. Creating awareness of FAI in GPs helps identifying patients that might benefit from FAI treatment. PMID:27583159

  7. The Epidemiology of Major Depressive Episode in the Iraqi General Population

    PubMed Central

    Al-Hamzawi, Ali Obaid; Bruffaerts, Ronny; Bromet, Evelyn J.; AlKhafaji, Abdulzahra Mohammed; Kessler, Ronald C.

    2015-01-01

    Objective To assess the prevalence, symptom severity, functional impairment, and treatment of major depressive episode (MDE) in the Iraqi general population. Methods The Iraq Mental Health Survey is a nationally representative face-to-face survey of 4,332 non-institutionalized adults aged 18+ interviewed in 2006–2007 as part of the WHO World Mental Health Surveys. Prevalence and correlates of DSM-IV MDE were determined with the WHO Composite International Diagnostic Interview (CIDI). Findings Lifetime and 12-month prevalence of MDE were 7.4% and 4.0%, respectively. Close to half (46%) of the 12-month MDE cases were severe/very severe. MDE was more common among women and those previously married. Median age of onset was 25.2. Only one-seventh of 12-month MDE cases received treatment despite being associated with very substantial role impairment (on average 70 days out of role in the past year). Conclusions MDE is a commonly occurring disorder in the Iraqi general population and is associated with considerable disability and low treatment. Efforts are needed to decrease the barriers to treatment and to educate general medical providers in Iraq about the recognition and treatment of depression. PMID:26230265

  8. The physics of anisotropic spheres in general relativity

    NASA Astrophysics Data System (ADS)

    Dev, Krsna

    2001-11-01

    We study the effects of anisotropic pressure on the properties of spherically symmetric, gravitationally bound spheres. We consider the full general-relativistic and Newtonian treatment of this problem and obtain exact solutions for various forms of the equation of state connecting the radial and tangential pressures. It is shown that pressure anisotropy can have significant effects on the structure and properties of both Newtonian and general relativistic spheres. We show that it is possible for Newtonian spheres to have an infinite core pressure without requiring the radius to be infinite and that there exists stable anisotropic spheres with adiabatic exponents less than 4/3. For general relativistic spheres we demonstrate that the maximum value of 2M/R can approach unity (2M/R < 8/9 for isotropic spheres) and the surface redshift can be arbitrarily large.

  9. Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population.

    PubMed

    Robinson, Elise B; St Pourcain, Beate; Anttila, Verneri; Kosmicki, Jack A; Bulik-Sullivan, Brendan; Grove, Jakob; Maller, Julian; Samocha, Kaitlin E; Sanders, Stephan J; Ripke, Stephan; Martin, Joanna; Hollegaard, Mads V; Werge, Thomas; Hougaard, David M; Neale, Benjamin M; Evans, David M; Skuse, David; Mortensen, Preben Bo; Børglum, Anders D; Ronald, Angelica; Smith, George Davey; Daly, Mark J

    2016-05-01

    Almost all genetic risk factors for autism spectrum disorders (ASDs) can be found in the general population, but the effects of this risk are unclear in people not ascertained for neuropsychiatric symptoms. Using several large ASD consortium and population-based resources (total n > 38,000), we find genome-wide genetic links between ASDs and typical variation in social behavior and adaptive functioning. This finding is evidenced through both LD score correlation and de novo variant analysis, indicating that multiple types of genetic risk for ASDs influence a continuum of behavioral and developmental traits, the severe tail of which can result in diagnosis with an ASD or other neuropsychiatric disorder. A continuum model should inform the design and interpretation of studies of neuropsychiatric disease biology. PMID:26998691

  10. Prevention of Recurrent Thrombosis in Antiphospholipid Syndrome: Different from the General Population?

    PubMed

    Legault, Kimberly Janet; Ugarte, Amaia; Crowther, Mark Andrew; Ruiz-Irastorza, Guillermo

    2016-05-01

    Antiphospholipid syndrome (APS) is characterized by arterial and/or venous thrombosis with or without pregnancy morbidity in the presence of autoantibodies targeting proteins that associate with membrane phospholipids, termed "antiphospholipid antibodies" (aPL). Management of arterial and venous thromboses shares some similarities with management of arterial and venous thromboses in the general population; however, there are key differences. The majority of studies addressing management of thrombotic APS focus on secondary prevention. Vitamin K antagonists (VKA) are typically used for secondary prevention of venous thromboembolism in APS. Optimal management of isolated arterial thrombosis, in particular ischemic stroke, in patients with APS is controversial, and proposed therapeutic options have included antiplatelet agents and VKA. Primary prophylaxis in aPL-positive patients should be an individualized decision taking into account patient-specific risks. There may be a role for adjuvant therapies such as hydroxychloroquine, vitamin D, statins, or novel therapeutics in specific patient populations. PMID:27032789

  11. [Anxiety and depression in the general population: normal values in the Hospital Anxiety and Depression Scale].

    PubMed

    Hinz, A; Schwarz, R

    2001-05-01

    For the Hospital Anxiety and Depression Scale (HADS) psychometric properties were tested and standardised values were calculated on the basis of a representative sample of the German adult population with 2037 persons. The main result was the evidence of age and gender differences for anxiety and depression. Females were more anxious than males. For both dimensions of the HADS a nearly linear age dependency was found which was more pronounced for depression (r = 0.36) than for anxiety (r = 0.14). Standardised values are given for different age and gender groups, and the results of regression analyses are presented. The psychometric properties were satisfying or good, the two-dimensional factorial structure could be replicated. By means of the standardised values and regression coefficients it is now possible to compare patient groups of different age and gender distributions with the general population. PMID:11417357

  12. Population genetics related to adaptation in elite oat germplasm

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Six hundred thirty five oat lines and 2,635 SNP loci were used to evaluate population structure, linkage disequilibrium (LD) and genotype-phenotype association with heading date. The first five principal components (PC) accounted for 25.3% of genetic variation. Neither the eigenvalues of the first 2...

  13. Incidence of Bicycle-Related Injuries in a Defined Population.

    ERIC Educational Resources Information Center

    Thompson, Diane C.; And Others

    1990-01-01

    Analysis of head injuries and total injuries resulting from bicycle crashes among members of a health maintenance organization. Injuries per 100,000 population, per 100 miles ridden, and according to season and day of the week are reported. Individuals between 5 and 14 are at highest risk. The data can be used in community bicycle helmet campaigns…

  14. Impact of occupational carcinogens on lung cancer risk in a general population

    PubMed Central

    De Matteis, Sara; Consonni, Dario; Lubin, Jay H; Tucker, Margaret; Peters, Susan; Vermeulen, Roel CH; Kromhout, Hans; Bertazzi, Pier Alberto; Caporaso, Neil E; Pesatori, Angela C; Wacholder, Sholom; Landi, Maria Teresa

    2012-01-01

    Background Exposure to occupational carcinogens is an important preventable cause of lung cancer. Most of the previous studies were in highly exposed industrial cohorts. Our aim was to quantify lung cancer burden attributable to occupational carcinogens in a general population. Methods We applied a new job–exposure matrix (JEM) to translate lifetime work histories, collected by personal interview and coded into standard job titles, into never, low and high exposure levels for six known/suspected occupational lung carcinogens in the Environment and Genetics in Lung cancer Etiology (EAGLE) population-based case–control study, conducted in Lombardy region, Italy, in 2002–05. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated in men (1537 cases and 1617 controls), by logistic regression adjusted for potential confounders, including smoking and co-exposure to JEM carcinogens. The population attributable fraction (PAF) was estimated as impact measure. Results Men showed an increased lung cancer risk even at low exposure to asbestos (OR: 1.76; 95% CI: 1.42–2.18), crystalline silica (OR: 1.31; 95% CI: 1.00–1.71) and nickel–chromium (OR: 1.18; 95% CI: 0.90–1.53); risk increased with exposure level. For polycyclic aromatic hydrocarbons, an increased risk (OR: 1.64; 95% CI: 0.99–2.70) was found only for high exposures. The PAFs for any exposure to asbestos, silica and nickel–chromium were 18.1, 5.7 and 7.0%, respectively, equivalent to an overall PAF of 22.5% (95% CI: 14.1–30.0). This corresponds to about 1016 (95% CI: 637–1355) male lung cancer cases/year in Lombardy. Conclusions These findings support the substantial role of selected occupational carcinogens on lung cancer burden, even at low exposures, in a general population. PMID:22467291

  15. Nightmares: Prevalence among the Finnish General Adult Population and War Veterans during 1972-2007

    PubMed Central

    Sandman, Nils; Valli, Katja; Kronholm, Erkki; Ollila, Hanna M.; Revonsuo, Antti; Laatikainen, Tiina; Paunio, Tiina

    2013-01-01

    Study Objectives: To investigate the prevalence of nightmares among the Finnish general adult population during 1972-2007 and the association between nightmare prevalence and symptoms of insomnia, depression, and anxiety in World War II veterans. Design: Eight independent cross-sectional population surveys of the National FINRISK Study conducted in Finland in 1972, 1977, 1982, 1987, 1992, 1997, 2002, and 2007. Setting: Epidemiologic. Participants: A total of 69,813 people (33,811 men and 36,002 women) age 25-74 years. Interventions: N/A. Measurements and Results: The investigation of nightmare prevalence and insomnia, depression, and anxiety symptoms was based on questionnaires completed by the participants. Among the whole sample, 3.5% of the men and 4.8% of the women reported frequent nightmares (P < 0.0001 for sex difference), but the prevalence was affected by the age of participants and the year of the survey. Nightmare prevalence increased with age, particularly among the men. The number of people reporting occasional nightmares increased roughly by 20% for both sexes from 1972 to 2007 (P < 0.0001). Participants with war experiences reported more frequent nightmares and symptoms of insomnia, depression, and anxiety than participants without such experiences (P < 0.0001). Conclusions: Prevalence of nightmares was affected by the sex and age of the participants, and occasional nightmares have become more common in Finland. Exposure to war elevates nightmare prevalence as well as insomnia, depression, and anxiety symptoms even decades after the war; large numbers of war veterans can affect nightmare prevalence on population level. Citation: Sandman N; Valli K; Kronholm E; Ollila HM; Revonsuo A; Laatikainen T; Paunio T. Nightmares: prevalence among the Finnish general adult population and war veterans during 1972-2007. SLEEP 2013;36(7):1041-1050. PMID:23814341

  16. Urinary excretion and daily intake rates of diethyl phthalate in the general Canadian population.

    PubMed

    Saravanabhavan, Gurusankar; Walker, Mike; Guay, Mireille; Aylward, Lesa

    2014-12-01

    We have analyzed the trends in the body-weight-adjusted urinary monoethyl phthalate (MEP) concentrations and the diethyl ethyl phthalate (DEP) daily intake estimates in the general Canadian population (aged 6-49 years) using the Canadian Health Measures Survey 2007-2009 dataset. The creatinine correction approach, as well as the urine volume approach in a simple one compartment model were used to calculate the daily urinary MEP excretion rates and DEP intake rates in individual survey participants. Using multiple regression models, we have estimated least square geometric means (LSGMs) of body-weight-adjusted MEP concentration, daily excretion and intake rates among different age groups and sex. We observed that body weight affects the trends in the MEP concentrations significantly among children (aged 6-11 years), adolescents (aged 12-19 years) and adults (aged 20-49 years). The body-weight-adjusted MEP concentrations in children were significantly higher than those in adults. On the other hand the DEP daily intakes in children were significantly lower than those in adults. We did not observe any differences in the DEP daily intake rates between males and females. Although the urinary MEP concentrations are correlated well with DEP daily intake estimates in the overall population, one should be cautious when directly using the urinary concentrations to compare the intake trends in the sub-populations (e.g. children vs. adults) as these trends are governed by additional physiological factors. The DEP daily intake calculated using the creatinine approach and that using the urine volume approach were similar to each other. The estimated geometric mean and 95th percentile of DEP daily intake in the general Canadian population are 2 and 20 μg/kg-bw/day, respectively. These daily intake estimates are significantly lower than the US Environmental Protection Agency's oral reference dose of 800 μg/kg-bw/day. PMID:25217994

  17. [The feminine role as a determinant of mental health among the women of the general population of Cantabria].

    PubMed

    de Santiago, A; Vázquez, J L; Díez, J F

    1993-01-01

    This paper tries to analyse the relationship between traditional feminine role (marriage, motherhood and housing) and mental health in spanish women. The General Health Questionnaire 60-items (GHQ-60) was used to define "cases" in a random sample of the general population of Cantabria consisting of 630 women aged 17 and over. The rate of probable prevalence of psychiatric disorders was 26.4%. In contrast to previous studies, motherhood and traditional feminine role correlated with the lowest GHQ-60 mean scores. Occupational status was not related to mental health. Women living with husband, children, parents and/or parents-in-law scored lower on GHQ-60 than those living with husband and children. These results are discussed in the light of previous findings in the literature. At least, they reconfirm the importance of socio-cultural factors in community psychiatric disorder. PMID:8135150

  18. Prediction models for cardiovascular disease risk in the general population: systematic review

    PubMed Central

    Hooft, Lotty; Schuit, Ewoud; Debray, Thomas P A; Collins, Gary S; Tzoulaki, Ioanna; Lassale, Camille M; Siontis, George C M; Chiocchia, Virginia; Roberts, Corran; Schlüssel, Michael Maia; Gerry, Stephen; Black, James A; Heus, Pauline; van der Schouw, Yvonne T; Peelen, Linda M; Moons, Karel G M

    2016-01-01

    Objective To provide an overview of prediction models for risk of cardiovascular disease (CVD) in the general population. Design Systematic review. Data sources Medline and Embase until June 2013. Eligibility criteria for study selection Studies describing the development or external validation of a multivariable model for predicting CVD risk in the general population. Results 9965 references were screened, of which 212 articles were included in the review, describing the development of 363 prediction models and 473 external validations. Most models were developed in Europe (n=167, 46%), predicted risk of fatal or non-fatal coronary heart disease (n=118, 33%) over a 10 year period (n=209, 58%). The most common predictors were smoking (n=325, 90%) and age (n=321, 88%), and most models were sex specific (n=250, 69%). Substantial heterogeneity in predictor and outcome definitions was observed between models, and important clinical and methodological information were often missing. The prediction horizon was not specified for 49 models (13%), and for 92 (25%) crucial information was missing to enable the model to be used for individual risk prediction. Only 132 developed models (36%) were externally validated and only 70 (19%) by independent investigators. Model performance was heterogeneous and measures such as discrimination and calibration were reported for only 65% and 58% of the external validations, respectively. Conclusions There is an excess of models predicting incident CVD in the general population. The usefulness of most of the models remains unclear owing to methodological shortcomings, incomplete presentation, and lack of external validation and model impact studies. Rather than developing yet another similar CVD risk prediction model, in this era of large datasets, future research should focus on externally validating and comparing head-to-head promising CVD risk models that already exist, on tailoring or even combining these models to local

  19. Descriptive epidemiology of stigma against depression in a general population sample in Alberta

    PubMed Central

    2010-01-01

    Background Mental health illnesses, such as depression, are responsible for a growing disease burden worldwide. Unfortunately, effective treatment is often impeded by stigmatizing attitudes of other individuals, which have been found to lead to a number of negative consequences including reduced help-seeking behavior and increased social distance. Despite the high prevalence of depression in Canada, little research has been conducted to examine stigma against depression in the Canadian general population. Such information is crucial to understanding the current state of stigmatizing attitudes in the Canadian communities, and framing future stigma reduction initiatives. The objectives of this study were to estimate the percentages of various stigmatizing attitudes toward depression in a general population sample and to compare the percentages by demographics and socioeconomic characteristics. Methods We conducted a cross-sectional telephone survey in Alberta, Canada, between February and June 2006. Random digit dialing was used to recruit participants who were aged 18-74 years old (n = 3047). Participants were presented a case vignette describing a depressed individual, and responded to a 9-item Personal Stigma questionnaire. The percentages of stigmatizing attitudes were estimated and compared by demographic and socioeconomic variables. Results Among the participants, 45.9% endorsed that depressed individuals were unpredictable and 21.9% held the view that people with depression were dangerous. Significant differences in stigmatizing attitudes were found by gender, age, education, and immigration status. A greater proportion of men than women held stigmatizing views on each stigma item. No consistent trend emerged by age in stigma against depression. Participants with higher levels of education reported less stigmatizing attitudes than those with less education. Participants who were not born in Canada were more likely to hold stigmatizing attitudes than those who

  20. Proton Pump Inhibitor Usage and the Risk of Myocardial Infarction in the General Population

    PubMed Central

    Bauer-Mehren, Anna; Ghebremariam, Yohannes T.; Iyer, Srinivasan V.; Marcus, Jake; Nead, Kevin T.; Cooke, John P.; Leeper, Nicholas J.

    2015-01-01

    Background and Aims Proton pump inhibitors (PPIs) have been associated with adverse clinical outcomes amongst clopidogrel users after an acute coronary syndrome. Recent pre-clinical results suggest that this risk might extend to subjects without any prior history of cardiovascular disease. We explore this potential risk in the general population via data-mining approaches. Methods Using a novel approach for mining clinical data for pharmacovigilance, we queried over 16 million clinical documents on 2.9 million individuals to examine whether PPI usage was associated with cardiovascular risk in the general population. Results In multiple data sources, we found gastroesophageal reflux disease (GERD) patients exposed to PPIs to have a 1.16 fold increased association (95% CI 1.09–1.24) with myocardial infarction (MI). Survival analysis in a prospective cohort found a two-fold (HR = 2.00; 95% CI 1.07–3.78; P = 0.031) increase in association with cardiovascular mortality. We found that this association exists regardless of clopidogrel use. We also found that H2 blockers, an alternate treatment for GERD, were not associated with increased cardiovascular risk; had they been in place, such pharmacovigilance algorithms could have flagged this risk as early as the year 2000. Conclusions Consistent with our pre-clinical findings that PPIs may adversely impact vascular function, our data-mining study supports the association of PPI exposure with risk for MI in the general population. These data provide an example of how a combination of experimental studies and data-mining approaches can be applied to prioritize drug safety signals for further investigation. PMID:26061035

  1. Can screening and brief intervention lead to population-level reductions in alcohol-related harm?

    PubMed

    Heather, Nick

    2012-01-01

    A distinction is made between the clinical and public health justifications for screening and brief intervention (SBI) against hazardous and harmful alcohol consumption. Early claims for a public health benefit of SBI derived from research on general medical practitioners' (GPs') advice on smoking cessation, but these claims have not been realized, mainly because GPs have not incorporated SBI into their routine practice. A recent modeling exercise estimated that, if all GPs in England screened every patient at their next consultation, 96% of the general population would be screened over 10 years, with 70-79% of excessive drinkers receiving brief interventions (BI); assuming a 10% success rate, this would probably amount to a population-level effect of SBI. Thus, a public health benefit for SBI presupposes widespread screening; but recent government policy in England favors targeted versus universal screening, and in Scotland screening is based on new registrations and clinical presentation. A recent proposal for a national screening program was rejected by the UK National Health Service's National Screening Committee because 1) there was no good evidence that SBI led to reductions in mortality or morbidity, and 2) a safe, simple, precise, and validated screening test was not available. Even in countries like Sweden and Finland, where expensive national programs to disseminate SBI have been implemented, only a minority of the population has been asked about drinking during health-care visits, and a minority of excessive drinkers has been advised to cut down. Although there has been research on the relationship between treatment for alcohol problems and population-level effects, there has been no such research for SBI, nor have there been experimental investigations of its relationship with population-level measures of alcohol-related harm. These are strongly recommended. In this article, conditions that would allow a population-level effect of SBI to occur are

  2. Can screening and brief intervention lead to population-level reductions in alcohol-related harm?

    PubMed Central

    2012-01-01

    A distinction is made between the clinical and public health justifications for screening and brief intervention (SBI) against hazardous and harmful alcohol consumption. Early claims for a public health benefit of SBI derived from research on general medical practitioners’ (GPs’) advice on smoking cessation, but these claims have not been realized, mainly because GPs have not incorporated SBI into their routine practice. A recent modeling exercise estimated that, if all GPs in England screened every patient at their next consultation, 96% of the general population would be screened over 10 years, with 70-79% of excessive drinkers receiving brief interventions (BI); assuming a 10% success rate, this would probably amount to a population-level effect of SBI. Thus, a public health benefit for SBI presupposes widespread screening; but recent government policy in England favors targeted versus universal screening, and in Scotland screening is based on new registrations and clinical presentation. A recent proposal for a national screening program was rejected by the UK National Health Service’s National Screening Committee because 1) there was no good evidence that SBI led to reductions in mortality or morbidity, and 2) a safe, simple, precise, and validated screening test was not available. Even in countries like Sweden and Finland, where expensive national programs to disseminate SBI have been implemented, only a minority of the population has been asked about drinking during health-care visits, and a minority of excessive drinkers has been advised to cut down. Although there has been research on the relationship between treatment for alcohol problems and population-level effects, there has been no such research for SBI, nor have there been experimental investigations of its relationship with population-level measures of alcohol-related harm. These are strongly recommended. In this article, conditions that would allow a population-level effect of SBI to occur are

  3. Disformal transformations, veiled General Relativity and Mimetic Gravity

    SciTech Connect

    Deruelle, Nathalie; Rua, Josephine E-mail: rua@cbpf.br

    2014-09-01

    In this Note we show that Einstein's equations for gravity are generically invariant under ''disformations''. We also show that the particular subclass when this is not true yields the equations of motion of ''Mimetic Gravity''. Finally we give the ''mimetic'' generalization of the Schwarzschild solution.

  4. Career Related Math Units for General Math 9.

    ERIC Educational Resources Information Center

    Grotenhuis, Paul; Purcell, Carol

    In this collection of four career-oriented units designed to enhance a ninth grade general math curriculum, the objectives listed are (1) to provide a job oriented environment in which students are encouraged to develop responsible attitudes toward employer and self and to find interest areas to use as the basis for career choices, (2) to provide…

  5. Language Generativity, Response Generalization, and Derived Relational Responding

    ERIC Educational Resources Information Center

    Stewart, Ian; McElwee, John; Ming, Siri

    2013-01-01

    Language generativity can be described as the ability to produce sentences never before said, and to understand sentences never before heard. One process often cited as underlying language generativity is response generalization. However, though the latter seems to promise a technical understanding of the former at a process level, an…

  6. Charged Analogues of Henning Knutsen Type Solutions in General Relativity

    NASA Astrophysics Data System (ADS)

    Gupta, Y. K.; Kumar, Sachin; Pratibha

    2011-11-01

    In the present article, we have found charged analogues of Henning Knutsen's interior solutions which join smoothly to the Reissner-Nordstrom metric at the pressure free interface. The solutions are singularity free and analyzed numerically with respect to pressure, energy-density and charge-density in details. The solutions so obtained also present the generalization of A.L. Mehra's solutions.

  7. Cooperative Work Education in Diversified Occupations. General Related Curriculum Guide.

    ERIC Educational Resources Information Center

    Brysgel, David

    This guide is intended as a working document for coordinators of cooperative work education in diversified occupations. It contains materials for use in providing students with general classroom instruction concurrent with on-the-job training. The following topics are covered in the individual units in the first-year curriculum: the cooperative…

  8. Collaboration between General Education Teachers and Related Service Providers

    ERIC Educational Resources Information Center

    Blask, Fallon

    2011-01-01

    Inclusion for students with disabilities into the general education classroom has grown exponentially over the last decade. With legislation, such as, No Child Left Behind (NCLB) and The Individuals with Disabilities Educational Improvement Act (IDEA) of 2004 schools are moving towards integrating their classrooms more than they ever have in the…

  9. Industrial Cooperative Training II. Curriculum Guide. General Related Study Units.

    ERIC Educational Resources Information Center

    Virginia Polytechnic Inst. and State Univ., Blacksburg. Div. of Vocational-Technical Education.

    Basic guidelines are offered for the teacher or coordinator who is working with second year Industrial Cooperative Training students (generally students at the twelfth grade level). The contents are organized into 12 units, with each unit including two to five lesson plans, transparencies (coded "T"), handouts (coded "H"), and a bibliography…

  10. Personality Factors Related to Career Satisfaction among General Practitioners.

    ERIC Educational Resources Information Center

    Schwartz, Robert H.; Shenoy, Sunil

    1994-01-01

    A survey of 150 general practice dentists examined the relationship between 6 career interests (scientific, artistic, social, enterprising, conventional, technical) and career satisfaction. Results are presented and compared with findings of other studies of dental students and practitioners. Results suggest that satisfied dentists tended to like…

  11. Generalizing the Nomological Network of Psychopathy across Populations Differing on Race and Conviction Status

    PubMed Central

    Vachon, David D.; Lynam, Donald R.; Loeber, Rolf; Stouthamer-Loeber, Magda

    2012-01-01

    Psychopathy has shown good construct validity in samples of Caucasian inmates. However, little is known about how well the nomological network surrounding psychopathy generalizes to non-Caucasian and non-incarcerated populations. Using longitudinal and concurrent data from the middle sample of the Pittsburgh Youth Study, this study demonstrates that the validity of total-and facet-level psychopathy is preserved in African American and non-incarcerated samples. Specifically, similar patterns of association were obtained for child variables (child psychopathy, SES, risk status, parenting, delinquency, peer delinquency, and impulsivity) and adult variables (children, education, incarceration, unemployment, personality, substance use, and APD) across ethnicity and arrest status. PMID:21842962

  12. Bedtime procrastination: A self-regulation perspective on sleep insufficiency in the general population.

    PubMed

    Kroese, Floor M; Evers, Catharine; Adriaanse, Marieke A; de Ridder, Denise Td

    2016-05-01

    Getting insufficient sleep has serious consequences in terms of mental and physical health. The current study is the first to approach insufficient sleep from a self-regulation perspective by investigating the phenomenon of bedtime procrastination: going to bed later than intended, without having external reasons for doing so. Data from a representative sample of Dutch adults (N = 2431) revealed that a large proportion of the general population experiences getting insufficient sleep and regularly goes to bed later than they would like to. Most importantly, a relationship between self-regulation and experienced insufficient sleep was found, which was mediated by bedtime procrastination. PMID:24997168

  13. Learning to pass: sex offenders' strategies for establishing a viable identity in the prison general population.

    PubMed

    Schwaebe, Charles

    2005-12-01

    This article endeavors to illustrate the realities of prison life for sex offenders and the means by which they attempt to establish viable identities and acquire a survivable niche in the prison general population, particularly when established identities and protective niches are put at risk by entry into a sex offender treatment program. Qualitative data was collected by repeatedly interviewing a cohort of sex offenders for 6 months as they completed a basic sex offender treatment program. The findings indicate a need to include consideration of treatment context in understanding the limits of treatment gain in prison-based programs. PMID:16249394

  14. Bird populations in relation to changes in land use

    USGS Publications Warehouse

    Warbach, O.

    1958-01-01

    Changes in breeding-bird populations on a 210-acre farm area were observed from 1947 to 1952. During this period, clearing, drainage, and planting changed the area from a partially abandoned farm with only 34 acres in cultivation to a modem conservation farm. Number of bird species nesting in the area was about 10 per cent lower in the last three years than in the first three years; number of nesting pairs declined about 40 per cent. The greatest decline was in species characteristic of brushy habitat; these were the most abundant birds on the area at the start of the study. For these species, approximately eight acres of planted hedges and field borders did not serve as an adequate substitute for 63 acres of brushy fields. Other birds were so limited in number during the breeding season that it is unsafe to conclude what effect agricultural practices had on their populations.

  15. Momentum in general relativity: local versus quasilocal conservation laws

    NASA Astrophysics Data System (ADS)

    Epp, Richard J.; McGrath, Paul L.; Mann, Robert B.

    2013-10-01

    We construct a general relativistic conservation law for linear and angular momentum for matter and gravitational fields in a finite volume of space that does not rely on any spacetime symmetries. This work builds on our previous construction of a general relativistic energy conservation law with the same features (McGrath et al 2012 Class. Quantum Grav. 29 215012). Our approach uses the Brown and York (1993 Phys. Rev. D 47 1407-19) quasilocal stress-energy-momentum tensor for matter and gravitational fields, plus the concept of a rigid quasilocal frame (RQF) introduced in (Epp et al 2009 Class. Quantum Grav. 26 035015; 2012 Classical and Quantum Gravity: Theory, Analysis, and Applications (Nova Science)). The RQF approach allows us to construct, in a generic spacetime, frames of reference whose boundaries are rigid (their shape and size do not change with time), and that have precisely the same six arbitrary time-dependent degrees of freedom as the accelerating and tumbling rigid frames we are familiar with in Newtonian mechanics. These RQFs, in turn, give rise to a completely general conservation law for the six components of momentum (three linear and three angular) of a finite system of matter and gravitational fields. We compare in detail this quasilocal RQF approach to constructing conservation laws with the usual local one based on spacetime symmetries, and discuss the shortcomings of the latter. These RQF conservation laws lead to a deeper understanding of physics in the form of simple, exact, operational definitions of gravitational energy and momentum fluxes, which in turn reveal, for the first time, the exact, detailed mechanisms of gravitational energy and momentum transfer taking place in a wide variety of physical phenomena, including a simple falling apple. As a concrete example, we derive a general relativistic version of Archimedes’ law that we apply to understand electrostatic weight and buoyant force in the context of a Reissner

  16. Asbestos Lung Burden in Necroscopic Samples from the General Population of Milan, Italy.

    PubMed

    Casali, Michelangelo; Carugno, Michele; Cattaneo, Andrea; Consonni, Dario; Mensi, Carolina; Genovese, Umberto; Cavallo, Domenico Maria; Somigliana, Anna; Pesatori, Angela Cecilia

    2015-08-01

    The present study analysed the asbestos lung burden in necroscopic samples from 55 subjects free from asbestos-related diseases, collected between 2009 and 2011 in Milan, Italy. Multiple lung samples were analysed by light microscopy (asbestos bodies, AB) and EDXA-scanning electron microscopy (asbestos fibres and other inorganic fibres). Asbestos fibres were detected in 35 (63.6%) subjects, with a higher frequency for amphiboles than for chrysotile. Commercial (CA) and non-commercial amphiboles (NCA) were found in roughly similar frequencies. The estimated median value was 0.11 million fibres per gram of dry lung tissue (mf g(-1)) for all asbestos, 0.09 mf g(-1) for amphiboles. In 44 (80.0%) subjects no chrysotile fibres were detected. A negative relationship between asbestos mass-weighted fibre count and year of birth (and a corresponding positive increase with age) was observed for amphiboles [-4.15%, 95% confidence interval (CI) = -5.89 to -2.37], talc (-2.12%, 95% CI = -3.94 to -0.28), and Ti-rich fibres (-3.10%, 95% CI = -5.54 to -0.60), but not for chrysotile (-2.84%, 95% CI = -7.69 to 2.27). Residential district, birthplace, and smoking habit did not affect the lung burden of asbestos or inorganic fibres. Females showed higher burden only for amphiboles (0.12 versus 0.03 mf g(-1) in males, P = 0.07) and talc fibres (0.14 versus 0 mf g(-1) in males, P = 0.03). Chrysotile fibres were shorter and thinner than amphibole fibres and NCA fibres were thicker than CA ones. The AB prevalence was 16.4% (nine subjects) with concentrations ranging from 10 to 110 AB g(-1) dry, well below the 1000 AB g(-1) threshold for establishing occupational exposure. No AB were found in subjects younger than 30 years. Our study demonstrated detectable levels of asbestos fibres in a sample taken from the general population. The significant increase with age confirmed that amphibole fibres are the most representative of cumulative exposure. PMID:25878166

  17. Generalized monogamy relations of concurrence for N -qubit systems

    NASA Astrophysics Data System (ADS)

    Zhu, Xue-Na; Fei, Shao-Ming

    2015-12-01

    We present a different kind of monogamous relations based on concurrence and concurrence of assistance. For N -qubit systems A B C1...CN -2 , the monogamy relations satisfied by the concurrence of N -qubit pure states under the partition A B and C1...CN -2 , as well as under the partition A B C1 and C2...CN -2 , are established, which gives rise to a kind of restrictions on the entanglement distribution and trade off among the subsystems.

  18. Preoperative ejection fraction as a predictor of survival after coronary artery bypass grafting: comparison with a matched general population

    PubMed Central

    2010-01-01

    Background Preoperative left ventricular dysfunction is an established risk factor for early and late mortality after revascularization. This retrospective analysis demonstrates the effects of preoperative ejection fraction on the short-term and long-term survival of patients after coronary artery bypass grafting. Methods Early and late mortality were determined retrospectively in 10 626 consecutive patients who underwent isolated coronary bypass between January 1998 and December 2007. The subjects were divided into 3 groups according to their preoperative ejection fraction. Expected survival was estimated by comparison with a general Dutch population group described in the database of the Dutch Central Bureau for Statistics. For each of our groups with a known preoperative ejection fraction, a general Dutch population group was matched for age, sex, and year of operation. Results and Discussion One hundred twenty-two patients were lost to follow-up. In 219 patients, the preoperative ejection fraction could not be retrieved. In the remaining patients (n = 10 285), the results of multivariate logistic regression and Cox regression analysis identified the ejection fraction as a predictor of early and late mortality. When we compared long-term survival and expected survival, we found a relatively poorer outcome in all subjects with an ejection fraction of < 50%. In subjects with a preoperative ejection fraction of > 50%, long-term survival exceeded expected survival. Conclusions The severity of left ventricular dysfunction was associated with poor survival. Compared with the survival of the matched general population, our coronary bypass patients had a worse outcome only if their preoperative ejection fraction was < 50%. PMID:20416050

  19. Meta-Analysis of Prognostic Implications of Exercise-Induced Ventricular Premature Complexes in the General Population.

    PubMed

    Kim, Joonseok; Kwon, Minkyung; Chang, Jinsoo; Harris, David; Gerson, Myron C; Hwang, Seung-Sik; Oh, Seung-Won

    2016-09-01

    Ventricular premature complexes (VPCs) during stress testing in the general population are commonly seen in clinical practice, but their prognostic value is not well understood. A comprehensive literature search of MEDLINE, Embase, and the Cochrane Library from January 1970 to May 2015 was conducted. Observational cohort studies on general populations evaluating the association between exercise-induced VPCs and all-cause or cardiovascular mortality were included in the analysis. Nine studies comprising 62,488 participants comparing clinical outcomes of patients with and without exercise-induced VPCs were included. The overall combined relative risks (RRs) for all-cause mortality and cardiovascular mortality in patients with exercise-induced VPCs were 1.41 (95% CI 1.23 to 1.61) and 1.86 (95% CI 1.51 to 2.30), respectively. In subgroup analysis, both frequent VPCs (RR 1.35, 95% CI 1.14 to 1.60) and infrequent VPCs (RR 1.57, 95% CI 1.13 to 2.18) were associated with an adverse outcome. VPCs during recovery were associated with an increased risk of death (RR 1.55, 95% CI 1.22 to 1.96). VPCs during exercise did not achieve statistical significance (RR 1.14, 95% CI 0.96 to 1.34), but only a few studies were included in the analysis. In conclusion, our meta-analysis suggests that exercise-induced VPCs in the general population significantly increase the risk of total mortality and cardiovascular mortality. Our study calls for further studies to assess the prognostic significance of exercise-induced VPCs and the utility of efforts to reduce the VPC burden to improve the clinical outcome. PMID:27394411

  20. Evidence of ancillary trigeminal innervation of levator palpebrae in the general population.

    PubMed

    Lehman, A M; Dong, C C; Harries, A M; Patel, A; Honey, C R; Patel, M S

    2014-02-01

    The cranial synkineses are a group of disorders encompassing a variety of involuntary co-contractions of the facial, masticatory, or extraocular muscles that occur during a particular volitional movement. The neuroanatomical pathways for synkineses largely remain undefined. Our studies explored a normal synkinesis long observed in the general population - that of jaw opening during efforts to open the eyelids widely. To document this phenomenon, we observed 186 consecutive participants inserting or removing contact lenses to identify jaw opening. Seeking electrophysiological evidence, in a second study we enrolled individuals undergoing vascular decompression for trigeminal neuralgia or hemifacial spasm, without a history of jaw-winking, ptosis, or strabismus, to record any motor responses in levator palpebrae superioris (LPS) upon stimulation of the trigeminal motor root. Stimulus was applied to the trigeminal motor root while an electrode in levator recorded the response. We found that 37 participants (20%) opened their mouth partially or fully during contact lens manipulation. In the second study, contraction of LPS with trigeminal motor stimulation was documented in two of six patients, both undergoing surgery for trigeminal neuralgia. We speculate these results might provide evidence of an endogenous synkinesis, indicating that trigeminal-derived innervation of levator could exist in a significant minority of the general population. Our observations demonstrate plasticity in the human cranial nerve innervation pattern and may have implications for treating Marcus Gunn jaw-winking. PMID:24120706