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1

Serotonin transporter binding of [123I]ADAM in bulimic women, their healthy twin sisters, and healthy women: a SPET study  

PubMed Central

Background Bulimia Nervosa (BN) is believed to be caused by an interaction of genetic and environmental factors. Previous studies support the existence of a bulimia-related endophenotype as well as disturbances in serotonin (5-HT) transmission. We studied serotonin transporter (SERT) binding in BN, and to investigate the possibility of a SERT-related endophenotype for BN, did this in a sample of female twins. We hypothesized clearly reduced SERT binding in BN women as opposed to healthy women, and intermediate SERT binding in unaffected co-twins. Methods We studied 13 female twins with BN (9 with purging and 4 with non-purging BN) and 25 healthy women, including 6 healthy twin sisters of BN patients and 19 women from 10 healthy twin pairs. [123I]ADAM, a selective SERT radioligand for single photon emission tomography (SPET) imaging, was used to assess SERT availability in the midbrain and the thalamus. Results No differences in SERT binding were evident when comparing the BN women, their unaffected co-twins and the healthy controls (p = 0.14). The healthy sisters of the BN patients and the healthy control women had similar SERT binding in both brain regions. In a post hoc subgroup analysis, the purging bulimics had higher SERT binding than the healthy women in the midbrain (p = 0.03), but not in the thalamus. Conclusion Our finding of increased SERT binding in the midbrain in the purging BN women raises the possibility that this subgroup of bulimics might differ in serotonergic function from the non-purging ones. The similarity of the unaffected co-twins and the healthy controls doesn't support our initial assumption of a SERT-related endophenotype for BN. Due to the small sample size, our results need to be interpreted with caution and verified in a larger sample. PMID:17511889

Koskela, Anu K; Keski-Rahkonen, Anna; Sihvola, Elina; Kauppinen, Tomi; Kaprio, Jaakko; Ahonen, Aapo; Rissanen, Aila

2007-01-01

2

Non-syndromic multiple hyperdontia in monozygotic twin sisters: a report of two cases.  

PubMed

Supernumerary teeth are common in the general population, with a prevalence that varies between 0.1 percent to 3.8 percent. Multiple supernumerary teeth are associated with Gardner's syndrome, Fabry-Anderson syndrome, Ehlers-Danlos syndrome, labial palatal cleft, and cleidocranial dysplasia. Multiple hyperdontia not associated with syndromes is rare and ranges between 0.04 percent to 0.1 percent. The purpose of this report was to describe the occurrence of nonsyndromic multiple hyperdontia in monozygotic twin sisters. PMID:24709435

Ratson, Tal; Peretz, Benjamin

2014-01-01

3

Delivery of a healthy twin after intrauterine demise and expulsion of a first twin.  

PubMed

We report on a diamniotic-dichorionic twin pregnancy after in vitro fertilization. The first twin was diagnosed with Down syndrome and spontaneously aborted at 24 weeks of gestation after intrauterine death at week 18. The second healthy twin was delivered by cesarean section 11 weeks later. We discuss management aspects and review the literature. PMID:16984521

Zeck, Willibald; Bjelic, Vesna; Petru, Edgar; Lang, Uwe

2006-10-01

4

Doing me! Sisters Working Together for a Healthy Mind and Body  

E-print Network

Doing me! Sisters Working Together for a Healthy Mind and Body: Lessons Learned from a Community B dHealthy Mind and Body #12;PurposePurpose Use a community-based participatory Use a community medical and behavioral illnesses. Leaders in research and clinical practice have noted, there is still

Illinois at Chicago, University of

5

Multiple risk factors related to familial predisposition to anterior cruciate ligament injury: fraternal twin sisters with anterior cruciate ligament ruptures  

PubMed Central

Objective A multifactorial combination of predictors may increase anterior cruciate ligament (ACL) injury risk in athletes. The objective of this twin study was to examine these risk factors to identify commonalities in risk factors that predisposed female fraternal twins to ACL injury. Methods Female twins in high-risk sports were prospectively measured prior to an injury for neuromuscular control using three-dimensional motion analysis during landing, hamstrings and quadriceps muscular strength on a dynamometer and joint laxity using a modified Beighton–Horan index and a Compu-KT arthrometer. Intraoperative measures of femoral intercondylar notch width were recorded during ACL reconstruction. Results Abduction angles were increased at one knee in both of the twin sister athletes relative to uninjured controls at initial contact and at maximum displacement during landing. The twin female athletes that went on to ACL injury also demonstrated decreased peak knee flexion motion at both knees than uninjured females during landing. The twin athletes also had increased joint laxity and decreased hamstrings to quadriceps (H/Q) torque ratios compared to controls. Femoral intercondylar notch widths were also below the control mean in the twin siblings. Conclusions Prescreened mature female twins that subsequently experienced ACL injury demonstrated multiple potential risk factors including: increased knee abduction angles, decreased knee flexion angles, increased general joint laxity, decreased H/Q ratios and femoral intercondylar notch width. PMID:19158132

Hewett, T E; Lynch, T R; Myer, G D; Ford, K R; Gwin, R C; Heidt, R S

2014-01-01

6

Novel insertion in exon 5 of the TCOF1 gene in twin sisters with Treacher Collins syndrome.  

PubMed

Treacher Collins syndrome (TCS) is associated with an abnormal differentiation of the first and second pharyngeal arches during fetal development. This causes mostly craniofacial deformities, which require numerous corrective surgeries. TCS is an autosomal dominant disorder and it occurs in the general population at a frequency of 1 in 50,000 live births. The syndrome is caused by mutations in the TCOF1 gene, which encodes the serine/alanine-rich protein named Treacle. Over 120 mutations of the TCOF1 gene responsible for TCS have been described. About 70% of recognized mutations are deletions, which lead to a frame shift, formation of a termination codon, and shortening of the protein product of the gene. Herewith, a new heterozygotic insertion, c.484_668ins185bp, was described in two monozygotic twin sisters suffering from TCS. This mutation was absent in their father, brother, and uncle, indicating a de novo origin. The insertion causes a shift in the reading frame and premature termination of translation at 167 aa. The novel insertion is the longest ever found in the TCOF1 gene and the only one found among monozygotic twin sisters. PMID:22415350

Marsza?ek-Kruk, Bo?ena Anna; Wójcicki, Piotr; Smigiel, Robert; Trzeciak, Wies?aw H

2012-08-01

7

Childhood obsessive-compulsive traits in anorexia nervosa patients, their unaffected sisters and healthy controls: a retrospective study.  

PubMed

Although there is evidence that childhood perfectionistic traits predate the onset of eating disorders, few studies to date have examined the prevalence and clinical correlates of these traits in patients with anorexia nervosa (AN) and their unaffected sisters. The aim of this work was to study the prevalence of childhood obsessive-compulsive traits in patients with lifetime AN, their unaffected sisters and healthy women. A total of 116 AN patients, 32 healthy sisters and 119 controls were assessed by the EATATE Interview to assess traits such as perfectionism, inflexibility, rule-bound traits, drive for order and symmetry, and excessive doubt and cautiousness. Both self-report and maternal reports were collected. AN patients reported more childhood obsessive-compulsive traits than their healthy sisters and controls. In contrast, no differences between healthy controls and unaffected sisters emerged. In patients with AN, a dose-response relationship was found between the number of childhood obsessive-compulsive traits and psychopathology, including body image distortion, thus indicating that these traits are an important feature to be considered in assessing and treating eating disorders. PMID:24851802

Degortes, Daniela; Zanetti, Tatiana; Tenconi, Elena; Santonastaso, Paolo; Favaro, Angela

2014-07-01

8

Strain localization associated with channelized melt migration in upper mantle lithosphere: Insights from the Twin Sisters ultramafic complex, Washington, USA  

NASA Astrophysics Data System (ADS)

We present results of field, microstructural, and textural studies in the Twin Sisters ultramafic complex (Washington State) that document localized deformation associated with the formation of dunite channels in naturally deformed upper mantle. The Twin Sisters complex is a well-exposed, virtually unaltered section of upper mantle lithosphere comprised largely of dunite and harzburgite (in cm- to m-scale primary compositional layers), and variably deformed orthopyroxenite and clinopyroxenite dikes. A series of ˜N-S striking, m-scale dunite bands (typically with porphyroclastic texture) occur throughout the study area and crosscut both the primary compositional layers and older orthopyroxenite dikes. Structural relationships suggest that these dunite bands represent former zones of channelized melt migration (i.e., dunite channels), and that strain localization was associated with melt migration. Early formed orthopyroxenite dikes are either absent within cross-cutting dunite channels, or have been displaced within channels relative to their position in the adjacent host rocks. These pre-existing orthopyroxenite dikes provide strain markers illustrating that displacement was localized primarily along channel margins, which have opposite senses of shear. In all cases where offsets were noted, the center of the channel was moved southward relative to its margins. Material flow and strain was, therefore, partitioned within channels during melt migration, and dunite channels did not accommodate net shear displacement of the adjacent host peridotites. Primary compositional layers adjacent to dunite channels document opposite rotation of olivine [100] crystallographic axes on either side of channel margins, consistent with the kinematic reversal inferred from offset markers at the outcrop scale, suggesting that the formation of dunite channels also induced host rock deformation proximal to channels. Strain localization that was focused at the margin of the bands was likely facilitated by melt-induced weakening. Channelized movement within the dunite bands may have resulted from matrix compaction within channels, pressure gradients during melt migration, or a combination of these processes during coaxial deformation.

Kruckenberg, Seth C.; Tikoff, Basil; Toy, Virginia G.; Newman, Julie; Young, Laura I.

2013-05-01

9

Lung volumes, ventilatory capacity, and transfer factor in healthy British boy and girl twins  

Microsoft Academic Search

Cotes, J. E., Dabbs, J. M., Hall, A. M., Axford, A. T., and Laurence, K. M. (1973). Thorax, 28, 709-715. Lung volumes, ventilatory capacity, and transfer factor in healthy British boy and girl twins. Normal values are reported for the lung volumes, ventilatory capacity, and transfer factor of 212 healthy British twin children aged 8 to 16 years. The boys

J. E. Cotes; J. M. Dabbs; A. M. Hall; A. T. Axford; K. M. Laurence

1973-01-01

10

Testing of the "Healthy 'Little' Lives Project": A Training Program for Big Sister Mentors  

ERIC Educational Resources Information Center

Big Brothers/Big Sisters is a national program aimed at providing mentors for disadvantaged children. This study tested whether Big Sister mentors could be trained to increase communication with their Little Sisters about sexual health issues. The study tested an intervention based on social cognitive theory in which a sexual health communication…

Kaufman, Michelle R.

2010-01-01

11

Testing of the Healthy “Little” Lives Project: A Training Program for Big Sister Mentors  

Microsoft Academic Search

Big Brothers\\/Big Sisters is a national program aimed at providing mentors for disadvantaged children. This study tested whether Big Sister mentors could be trained to increase communication with their Little Sisters about sexual health issues. The study tested an intervention based on social cognitive theory in which a sexual health communication program was tested against an attention-matched control condition (bullying\\/peer

Michelle R. Kaufman

2010-01-01

12

Twins  

NSDL National Science Digital Library

This collection of Web sites about twins and twin biology starts with a short feature from The Straight Dope (1), which explains the phenomenon of superfecundation. Next is a more extensive piece from Scientific American (2), offering an interesting look at the role genetics may play in the chance of having fraternal twins. The following Web site contains a brief MSNBC story on the recent findings that fraternal, or nonidentical, twins can share the same placenta (3). The Wisconsin Twin Project at the University of Wisconsin-Madison is a long-scale psychological study focused on "the genetic and environmental influences on normal development of twins in the family context." Visitors to the project's Web site (4) will find detailed information about the ongoing research as well as FAQs for general background information. On the topic of twin studies, the next Web site contains a transcript from a recent Health Report story from the Australian Broadcasting Company's Radio National. The transcript is an interview with a researcher working with the Swedish Twin Registry (the largest twin register in the world), an important resource for studying the "relative importance of genetic and environmental influences for behavioral characteristics and diseases (5). The journal Nature offers an interesting article on how the environment in the womb can have profound effects on a child's future health without altering its DNA sequence (6). The following Web site, created by Varun Tankala, offers an excellent introduction to the phenomenon of conjoined twins (7). And with the final Web site, you need not spend another restless night wondering which Star Wars character is your cosmic twin. Not as frivolous as it might seem, this Web site, created by Jeff Potter, contains a well-accepted personality test developed by a University of California-Berkeley psychologist. Users can take the test, find their Star Wars twin, and help advance the field of psychology while you're at it (8).

13

Sister Study  

Cancer.gov

The Sister Study, conducted by the National Institute of Environmental Health Sciences (NIEHS), is prospectively examining environmental and familial risk factors for breast cancer and other outcomes in a cohort of 50,884 sisters of women who have had breast cancer. These sisters have about twice the risk of developing breast cancer due to their family history and are expected to be highly motivated to participate in a long-term study.

14

SISTER STUDY  

EPA Science Inventory

The Sister Study will investigate the role of genetic, environmental, and lifestyle factors on the risk of breast cancer and other diseases in sisters of women with breast cancer. This research study will enroll 50,000 women who live in the United States and who are the cancer-fr...

15

CEO Sister  

NSDL National Science Digital Library

Touted as the "nation's Number One destination for Minority Businesswomen," CEO Sister is designed to serve as an online community for businesswomen of color. Highlighted on the site are headlines from both the Washington Post and US News. A menu of resources is located in a blue box on the upper left corner of the site and contains information on higher education, ecommerce, and networking. Interested users may register to receive a lifetime email account with the site as well as access to chats and bulletin boards.

16

Discordance for achalasia in identical twins  

Microsoft Academic Search

Twenty-year-old twin sisters, believed monozygotic on the basis of extensive blood grouping and cytogenetic studies, are reported. One twin demonstrated classical clinical, radiologic, and manometric features of achalasia, while similar studies in her sister documented perfectly normal esophageal motor function. Genetically determined damage to the esophageal parasympathetic innervation is, therefore, not a likely cause for the esophageal motor dysfunction in

John D. Eckrich; Charles S. Winans

1979-01-01

17

Ectrodactyly in sisters and half sisters.  

PubMed Central

An extended family is described in which four sisters and half sisters presented with ectrodactyly. Two of the sisters had associated agenesis of the tibiae. The paper describes the malformations and discusses the management and possible genetic inheritance involved. An autosomal recessive gene seems likely to be the mode of inheritance. Images PMID:3585937

Mufti, M H; Wood, S K

1987-01-01

18

Does education confer a culture of healthy behavior? Smoking and drinking patterns in Danish twins.  

PubMed

More education is associated with healthier smoking and drinking behaviors. Most analyses of effects of education focus on mean levels. Few studies have compared variance in health-related behaviors at different levels of education or analyzed how education impacts underlying genetic and environmental sources of health-related behaviors. This study explored these influences. In a 2002 postal questionnaire, 21,522 members of the Danish Twin Registry, born during 1931-1982, reported smoking and drinking habits. The authors used quantitative genetic models to examine how these behaviors' genetic and environmental variances differed with level of education, adjusting for birth-year effects. As expected, more education was associated with less smoking, and average drinking levels were highest among the most educated. At 2 standard deviations above the mean educational level, variance in smoking and drinking was about one-third that among those at 2 standard deviations below, because fewer highly educated people reported high levels of smoking or drinking. Because shared environmental variance was particularly restricted, one explanation is that education created a culture that discouraged smoking and heavy drinking. Correlations between shared environmental influences on education and the health behaviors were substantial among the well-educated for smoking in both sexes and drinking in males, reinforcing this notion. PMID:21051448

Johnson, Wendy; Kyvik, Kirsten Ohm; Mortensen, Erik L; Skytthe, Axel; Batty, G David; Deary, Ian J

2011-01-01

19

Eating behaviors and weight over time in a prospective study: the Healthy Twin Study.  

PubMed

We examined the relationships of combined initial restrained and external/emotional eating with initial BMI and change in weight and these subscales over time. BMI and the Dutch Eating Behavior Questionnaire were twicemeasured in 1361 Korean twins and families (482 men, 879 women) over a period of 2.7±0.9 years. Subjects were classified by combination of initial sex-specific restrained and external (or emotional) eating tertiles. Linear mixed models were performed after adjusting for confounders at baseline (household, sibling relations, sex, age, education level, smoking, alcohol use, energy intake, physical activity, and medical history). In adjusted models, initial BMI increased with increasing tertiles of initial restrained eating across initial external/emotional eating tertiles. Weight was less likely to increase over time with increasing tertiles of initial restrained eating in the lowest external eating tertile and middle tertile of emotional eating at baseline. Subscale scores decreased over time with increasing tertiles of corresponding subscales at baseline. These findings suggest that high dietary restraint and external/emotional eating may indicate concurrent high BMI and attenuated weight gain and decreases in corresponding subscales over time. PMID:24561975

Song, Yun-Mi; Lee, Kayoung; Sung, Joohon

2014-01-01

20

Middle Sister and Hayden Glacier  

USGS Multimedia Gallery

The North face of Middle Sister and Hayden Glacier, in Three Sisters Wilderness, Deschutes National Forest, Oregon. This Picture was taken while climbing Middle Sister. Middle Sister is also known as "Hope" and is an extinct stratovolcano....

2009-12-08

21

When You Are a Twin or Triplet  

MedlinePLUS

... meaning that if your grandmother is a twin, your mom probably isn't, and you could be), but ... With Brothers and Sisters Things to Expect When Your Mom Is Pregnant Welcoming a New Baby Into Your ...

22

Dietary Restraint Is Non-Genetically Associated with Change in Body Mass Index: The Healthy Twin Study  

PubMed Central

Purpose We aimed to examine if past and more recent body mass index (BMI) changes are associated with eating behavior (EB) traits and whether these associations are due to non-genetic factors. Materials and Methods In 1321 Korean twins and family members, recent and past BMI change groups were defined using quartiles of BMI change between first and second visits over 2.4±0.9 years and BMI change between 20 years old and second visit, respectively. We applied linear mixed analysis for relationships of past or recent BMI change groups and each EB (restrained, external, and emotional EB using the Dutch Eating Behavior Questionnaire) assessed at second visit after adjusting for household effect and covariates (age, gender, education, medical history of diabetes, hypertension, and dyslipidemia, alcohol use, physical activity, smoking habit, and calorie intake). In monozygotic twin pairs, paired t-test for within-pair comparison and conditional logistic regression analysis were conducted regarding EB. Results Greater past BMI change was associated with higher restrained eating scores (P for trend=0.031), whereas greater recent BMI change was associated with higher external eating scores (P for trend=0.046). In co-twin-control analysis, twins with greater past BMI change were more likely to have higher restrained eating scores as compared with their co-twins with lower past BMI change (odds ratio 1.80; 95% confidence interval 1.13-2.87), whereas there were no associations between recent BMI change and external eating scores. Conclusion Greater BMI change since 20 years old is associated with higher dietary restraint, and non-genetic factors explain this relationship. PMID:24954348

Sung, Joohon; Song, Yun-Mi

2014-01-01

23

Genetic and Environmental Influences on the Wisconsin Card Sorting Test Performance in Healthy Adolescents: A Twin\\/Sibling Study  

Microsoft Academic Search

This study aimed to estimate the relative contributions from genetic and environmental factors to the Wisconsin Card Sorting\\u000a Test (WCST) performance, a widely used measurement for assessing frontal lobe function. Participants included 350 pairs of\\u000a twins (257 MZ and 93 DZ) and 47 same-sex sib-pairs, aged 12–16 years, systematically recruited from junior high schools in\\u000a Taipei. A computerized version of the

Lin-Na Chou; Po-Hsiu Kuo; Chaucer C. H. Lin; Wei J. Chen

2010-01-01

24

"Do you want somebody treating your sister like that?": qualitative exploration of how African American families discuss and promote healthy teen dating relationships.  

PubMed

The article discusses a study conducted between December 2007 and March 2008 that involved 19 gender-stratified focus groups with African American parents and adolescents from Allegheny County, Pennsylvania, to explore the process and content of parent-adolescent communication about sex. Discussions about intimate partner violence (IPV) and healthy relationships emerge inductively as critical topics in these conversations. The authors use a grounded theory approach to content analysis to identify and organize themes related to discussions on these topics. A total of 125 participants from 52 families are recruited for the study. Family history of child sexual abuse often motivates discussions. Mothers are described as the primary parent discussing sexual issues with children. Fathers primarily role model ideal male partnership behavior for sons and daughters. Parents seek to prevent daughters from experiencing sexual abuse or emotional manipulation by partners and focus on instilling a sense of responsibility to and respect for romantic partners in sons. Parents prioritize and express the need for tools to influence their adolescent's socialization as romantic partners. Mothers and fathers approach this process differently. Family-focused interventions to prevent unhealthy relationships can build on parent's efforts. PMID:20889536

Akers, Aletha Y; Yonas, Michael; Burke, Jessica; Chang, Judy C

2011-07-01

25

Sister Wendy's American Collection  

NSDL National Science Digital Library

In conjunction with the broadcast of "Sister Wendy's American Collection" on public television, PBS online hosts this educational Website. Sister Wendy is a Reverend Mother and scholar of English who began studying art during her stay with the Carmelite nuns of Quindenham, Norfolk. She now has a popular television and book series in which she shares her "signature blend of intellect, reverence, and admiration for great works of art." Her latest project explores American museum collections. The Website furnishes color images of the works accompanied by Sister Wendy's equally colorful commentary, background on the artists, plus a guide to the six museums featured. The diverse international selection of art and artifacts includes a Native American earthen bowl, an African drum, Egyptian statuary, as well as an array of classical to contemporary paintings and drawings.

2001-01-01

26

One Sister's Story  

MedlinePLUS

... please turn Javascript on. Tina (left) and Wanda Hall Photo courtesy of NIH/NIEHS By Tina Hall Sister Study participant One day in April, after ... and genetic issues that may contribute to the development of breast cancer. This research is only beneficial ...

27

The Prodigal Sister - Venus  

NASA Astrophysics Data System (ADS)

If you think Venus is a hellhole now, be thankful you weren't there 500 million years ago. Those were the days, many planetary scientists believe, of apocalypse on our sister world: Volcanoes wracked the land, while greenhouse gases broiled the air. Is this the Earth's fate, too?

Barlow, Nadine G.

1995-09-01

28

Sister Chromatid Cohesion  

PubMed Central

During S phase, not only does DNA have to be replicated, but also newly synthesized DNA molecules have to be connected with each other. This sister chromatid cohesion is essential for the biorientation of chromosomes on the mitotic or meiotic spindle, and is thus an essential prerequisite for chromosome segregation. Cohesion is mediated by cohesin complexes that are thought to embrace sister chromatids as large rings. Cohesin binds to DNA dynamically before DNA replication and is converted into a stably DNA-bound form during replication. This conversion requires acetylation of cohesin, which in vertebrates leads to recruitment of sororin. Sororin antagonizes Wapl, a protein that is able to release cohesin from DNA, presumably by opening the cohesin ring. Inhibition of Wapl by sororin therefore “locks” cohesin rings on DNA and allows them to maintain cohesion for long periods of time in mammalian oocytes, possibly for months or even years. PMID:23043155

Peters, Jan-Michael; Nishiyama, Tomoko

2012-01-01

29

Isolated oligodontia in monozygotic twins  

PubMed Central

This case report defines a case of isolated oligodontia of 9 and 10 permanent teeth in 9-year-old monozygotic twin sisters and gives information about the possible genetic and environmental etiology, related dental anomalies and treatment options. The twins have a negative family history of hypodontia and oligodontia in their parents, as well as their paternal and maternal grandmothers and first cousins. No other dental anomalies could be detected in either of the twins. With the occurrence of similarly located tooth agenesis, except for one tooth, in monozygotic twins, one may consider the influence of genetic and/or environmental factors in their etiology. Hereditary relationships associated with oligodontia could help the clinicians to predict the possibility of its occurrence in other family members and in the next generations. However, clinicians should consider oligodontia when it is not hereditary. PMID:24966717

Halicioglu, Koray; Sahin, Hakan; Corekci, Bayram; Irgin, Celal; Toptas, Orcun

2013-01-01

30

The sisters of mindfulness.  

PubMed

This article introduces the issue of Journal of Clinical Psychology: In Session entitled "Beyond Meditation: Mindfulness-Related Clinical Practices." In the article, I describe how the "sisters of mindfulness"-forgiveness, gratitude, loving-kindness, compassion, acceptance, and best-self visualization-are each interconnected and important forms of mindfulness as well as tenets of Buddhist psychology. Each of these practices reflect mental strengths that are being integrated into the brain's neuroplastic development as a function of modern day psychotherapy. PMID:23775372

Rosenzweig, Debra

2013-08-01

31

Sister kinetochores are mechanically fused during meiosis I in yeast.  

PubMed

Production of healthy gametes requires a reductional meiosis I division in which replicated sister chromatids comigrate, rather than separate as in mitosis or meiosis II. Fusion of sister kinetochores during meiosis I may underlie sister chromatid comigration in diverse organisms, but direct evidence for such fusion has been lacking. We used laser trapping and quantitative fluorescence microscopy to study native kinetochore particles isolated from yeast. Meiosis I kinetochores formed stronger attachments and carried more microtubule-binding elements than kinetochores isolated from cells in mitosis or meiosis II. The meiosis I-specific monopolin complex was both necessary and sufficient to drive these modifications. Thus, kinetochore fusion directs sister chromatid comigration, a conserved feature of meiosis that is fundamental to Mendelian inheritance. PMID:25213378

Sarangapani, Krishna K; Duro, Eris; Deng, Yi; Alves, Flavia de Lima; Ye, Qiaozhen; Opoku, Kwaku N; Ceto, Steven; Rappsilber, Juri; Corbett, Kevin D; Biggins, Sue; Marston, Adèle L; Asbury, Charles L

2014-10-10

32

Sister-sister incest: data from an anonymous computerized survey.  

PubMed

Retrospective data were entered anonymously by 1,521 adult women using a computer-assisted self-interview. Thirty-one participants were victims of sister-sister incest, 40 were victims of brother-sister incest, 19 were victims of father-daughter incest, 8 were victims of sexual abuse by an adult female (including one mother), and 232 were victims of sexual abuse by an adult male other than their father before reaching 18 years of age. The rest (1,203) served as controls. The victims of sister-sister incest had significantly more problematic outcomes than controls on many measures as adults. Victims of sister-sister incest were more depressed and more likely than controls to be distant from the perpetrator-sister and to have traded sex for money, experienced an unplanned pregnancy, engaged in four different types of masturbation, and engaged in 13 different same-sex behaviors. Our findings were consistent with other reports of early eroticization and persistent hypereroticization of incest victims. PMID:23924178

Stroebel, Sandra S; O'Keefe, Stephen L; Griffee, Karen; Kuo, Shih-Ya; Beard, Keith W; Kommor, Martin J

2013-01-01

33

Sister Cities International  

NSDL National Science Digital Library

People from around the world have sought to establish links with other individuals from different nations, and since 1956, cities have sought to also establish meaningful relationships with other urban areas through the Sister Cities International organization. Currently, the organization represents more than 2,500 communities in 126 countries. Visitors to the site can learn which cities are currently seeking partnerships with other cities, read about the organization's annual conference, and also read about the programs they administer. Also, its calendar of events is quite full with programs designed for the general public, such as those dealing with relationships with countries in the Middle East and the question of local government. Finally, the material on the site is available in a number of different languages, including French, German, Spanish, and Japanese.

34

A Comprehensive Neuropsychiatric Study of Elderly Twins: The Older Australian Twins Study  

Microsoft Academic Search

he Older Australian Twins Study (OATS) was recently initiated to investigate genetic and environ- mental factors and their associations and interactions in healthy brain ageing and ageing-related neurocognitive disorders. The study extends the classic MZ-DZ design to include one or two equivalently aged siblings for each twin pair and utilizes the rich resources of the Australian Twin Registry. The study

Perminder S. Sachdev; Andrea Lammel; Julian N. Trollor; Teresa Lee; Margaret J. Wright; David Ames; Wei Wen; Nicholas G. Martin; Henry Brodaty; Peter R. Schofield

2009-01-01

35

Brothers, Sisters and Aging Parents  

E-print Network

Adult children play a crucial role in helping aging parents. When relationships with siblings are poor, everyone suffers. Brothers and sisters can build strong relationships and unite in caring for elderly parents when they learn to relate to each...

Isbell, Lou

1999-09-02

36

Where are Sedna's Sisters?  

NASA Astrophysics Data System (ADS)

Simulations of the formation of the Oort cloud from the Kuiper Belt typically are presented as an animated scatter diagram. Here the orbit of each object appears as a point of perihelion distance q and semi-major axis a. (eg. Levison, Morbidelli, & Dones 2004). These plots show a conspicuous void, bounded by the inequalities: q < a, q > 50 AU, and a < 5000-10000 AU. Brown (2005) calls this void the ``Bermuda Triangle". The only present occupant is Sedna (q=76 AU, a=501 AU). Brown, Trujillo, & Rabinowitz , the discovers of Sedna, have challenged others to explain how Sedna got inside the triangle and to predict where similar objects might be found. Sedna could not have simply formed in its current orbit by the accumulation of smaller objects (Stern 2005). Several authors have suggested that a passing star scattered Sedna into the triangle shortly after the birth of the solar system. Here I offer an alternative which uses the very strong galactic tidal forces of the Sinusoidal potential (Bartlett 2001, 2004). In this potential, the numerator of Newton's law is replaced by GM cos(ko r) where ko = 2 ? / lambdao and the 'wavelength' ? o is 425 pc. The 20 radial oscillations between the sun and the center of the Galaxy give tidal forces that are 120 times as big as generally expected. I will show how this tidal force, acting over the lifetime of the solar system, could move the perihelion of Sedna from about 40 to 76 AU. Sedna's sisters are likely to have still larger q & a and to have perihelia in two specific quadrants of the ecliptic plane.

Bartlett, D. F.

2005-05-01

37

NK cells from an AML patient have recovered in remission and reached comparable cytolytic activity to that of a healthy monozygotic twin mediated by the single-chain triplebody SPM-2  

PubMed Central

Background The capacity of patient’s Natural Killer cells (NKs) to be activated for cytolysis is an important prerequisite for the success of antibody-derived agents such as single-chain triplebodies (triplebodies) in cancer therapy. NKs recovered from AML patients at diagnosis are often found to be reduced in peripheral blood titers and cytolytic activity. Here, we had the unique opportunity to compare blood titers and cytolytic function of NKs from an AML patient with those of a healthy monozygotic twin. The sibling’s NKs were compared with the patient’s drawn either at diagnosis or in remission after chemotherapy. The cytolytic activities of NKs from these different sources for the patient’s autologous AML blasts and other leukemic target cells in conjunction with triplebody SPM-2, targeting the surface antigens CD33 and CD123 on the AML cells, were compared. Methods Patient NKs drawn at diagnosis were compared to NKs drawn in remission after chemotherapy and a sibling’s NKs, all prepared from PBMCs by immunomagnetic beads (MACS). Redirected lysis (RDL) assays using SPM-2 and antibody-dependent cellular cytotoxicity (ADCC) assays using the therapeutic antibody RituximabTM were performed with the enriched NKs. In addition, MACS-sorted NKs were analyzed for NK cell activating receptors (NCRs) by flow cytometry, and the release of TNF-alpha and IFN-gamma from blood samples of both siblings after the addition of the triplebody were measured in ELISA-assays. Results Patient NKs isolated from peripheral blood drawn in remission produced comparable lysis as NKs from the healthy twin against the patient’s autologous bone marrow (BM) blasts, mediated by SPM-2. The NCR receptor expression profiles on NKs from patient and twin were similar, but NK cell titers in peripheral blood were lower for samples drawn at diagnosis than in remission. Conclusions Peripheral blood NK titers and ex vivo cytolytic activities mediated by triplebody SPM-2 were comparable for cells drawn from an AML patient in remission and a healthy twin. If these results can be generalized, then NKs from AML patients in remission are sufficient in numbers and cytolytic activity to make triplebodies promising new agents for the treatment of AML. PMID:24237598

2013-01-01

38

Healthy Foods, Healthy Lives Institute Planning Grants Awarded Spring 2013  

E-print Network

Healthy Foods, Healthy Lives Institute Planning Grants Awarded Spring 2013 "Achieving Healthy and healthy food access for low-income and communities of color in the Twin Cities. The partners will work and provide healthier menu items for its patients in hopes of producing healthy eating habits, reducing diet

Amin, S. Massoud

39

Eruptive history of South Sister, Oregon Cascades  

Microsoft Academic Search

South Sister is southernmost and highest of the Three Sisters, three geologically dissimilar stratovolcanoes that together form a spectacular 20km reach along the Cascade crest in Oregon. North Sister is a monotonously mafic edifice as old as middle Pleistocene, Middle Sister a basalt–andesite–dacite cone built between 48 and 14ka, and South Sister is a basalt-free edifice that alternated rhyolitic and

Judy Fierstein; Wes Hildreth; Andrew T. Calvert

2011-01-01

40

Fulfilling the sisters' promise. The heritage of healthcare's early days.  

PubMed

Members of religious orders--the sisters--built not just Catholic healthcare, but healthcare in America. A good 50 years before Henry and Edgar Kaiser got the idea, prepaid capitated health insurance was being offered by sisters who looked at what was needed and realized this was simply the best way to get it done. The sisters also created the integrated healthcare system at a time when the emerging medical elite wanted nothing to do with any patient who was not socially acceptable and potentially curable. They arranged a continuum of care for the aging sisters within their own communities. And they understood the concept of social medicine, of population-based healthcare, of healthy communities, long before these ideas became commonplace. But the sisters are gone, most of them. The question today is, How do we preserve the sisters' heritage and transfer it to a new millennium, a new healthcare system, and a new set of rules? First, it is important to understand that much of what we remember the sisters for--courage, compassion, vision-was not unique. They created many of the structures that today are the new models; but they were not alone. However, three aspects of how they expressed their vision and their faith were unique to the sisters and must be understood by those who wish to treat the path the sisters blazed. The purity of their commitment and its underlying philosophy--that the helpless and the sick must always be the point of the exercise--should pervade Catholic healthcare to its soul. These women, living in poverty, represented, and still represent, a singular group: a group of women who, having told the world that their only wish is to serve others, humble became CEOs of vast systems and trustees of huge enterprises, without ever abandoning that simple, original pledge. Although they bowed to the rule of obedience, and they were humble, the were fighters. They spoke out against poverty, bigotry, the shunning of those with certain diseases, lack of access to healthcare, stupidity, ignorance, and hate. PMID:10165751

Friedman, E

1997-01-01

41

A study of lactose absorption capacity in twins  

Microsoft Academic Search

Lactose absorption capacity was determined by lactose tolerance tests with breath hydrogen determination in 102 healthy, adult, Hungarian pairs of twins in order to test monogenic Mendelian inheritance of the absorptive lactase phenotypes, lactose absorber and lactose malabsorber. Of the total, 52 pairs were monozygous (MZ) and 50 dizygous (DZ) twins of indentical sex. All MZ twins were concordant with

Julia Métneki; A. Czeizel; Sibylle D. Flatz; G. Flatz

1984-01-01

42

A Tale of Two Sisters  

ERIC Educational Resources Information Center

How many children benefit in many diverse ways through art and/or design? Their personalities may draw different benefits and attributes, but that attests to its wide scope. This article relates a brief story of two sisters. The author describes how the siblings' different personalities played a role in their success.

Caouette, Ralph

2009-01-01

43

Chromosome cohesion: ring around the sisters?  

Microsoft Academic Search

Sister chromatid cohesion is a key aspect of accurate chromosome transmission during mitosis, yet little is known about the structure of cohesin, the protein complex that links the two sister chromatids. Recent studies shed light on the structure of the cohesin complex, leading to intriguing models that could explain how sister chromatids are held together.

Joseph L Campbell; Orna Cohen-Fix

2002-01-01

44

A monozygotic twin pair with highly discordant Gaucher phenotypes.  

PubMed

We describe monozygotic twin sisters, born to consanguineous Moroccan parents, who are highly discordant for the manifestations of Gaucher disease. Both carry Gaucher genotype N188S/N188S. One has severe visceral involvement, epilepsy, and a cerebellar syndrome. Her twin does not manifest any symptoms or signs of Gaucher disease but suffers from type 1 diabetes mellitus. The concurrence of a mild Gaucher mutation with a severe phenotype, as well as the occurrence of highly discordant phenotypes in a pair of monozygotic twins, is discussed. PMID:21056933

Biegstraaten, M; van Schaik, I N; Aerts, J M F G; Langeveld, M; Mannens, M M A M; Bour, L J; Sidransky, E; Tayebi, N; Fitzgibbon, E; Hollak, C E M

2011-01-15

45

A monozygotic twin pair with highly discordant Gaucher phenotypes  

PubMed Central

We describe monozygotic twin sisters, born to consanguineous Moroccan parents, who are highly discordant for the manifestations of Gaucher disease. Both carry Gaucher genotype N188S/N188S. One has severe visceral involvement, epilepsy, and a cerebellar syndrome. Her twin does not manifest any symptoms or signs of Gaucher disease but suffers from type 1 diabetes mellitus. The concurrence of a mild Gaucher mutation with a severe phenotype, as well as the occurrence of highly discordant phenotypes in a pair of monozygotic twins, is discussed. PMID:21056933

Biegstraaten, M.; van Schaik, I.N.; Aerts, J.M.F.G.; Langeveld, M.; Mannens, M.M.A.M.; Bour, L.J.; Sidransky, E.; Tayebi, N.; Fitzgibbon, E.; Hollak, C.E.M.

2012-01-01

46

NOVA Online: Titanic's Lost Sister  

NSDL National Science Digital Library

Companion site to an original broadcast on January 28, 1997. When Titanic sank, construction on her sister ship, Britannic, was interrupted so she could be overhauled with new regulations. Britannic sank in 1916 in less than an hour. Includes interview with Robert Ballard, who found the sunken Titanic, an interactive search, and salvage activity. Others resources available: written transcript, teacher's guide, students activities, and links to additional resources.

47

Pregnancy and lactation have no long-term deleterious effect on measures of bone mineral in healthy women: a twin study1-3  

Microsoft Academic Search

Background: The long-term effects of pregnancy and lactation on measures of bone mineral in women remain unclear. Objective: We studied whether pregnancy or lactation has dele- terious long-term effects on bone mineral in healthy women. Design: We measured bone mineral density (BMD; g\\/cm2) in women aged ? 18 y. Analyses were performed on 3 data sets: study 1, 83 female

Lynda M Paton; Jo L Alexander; Caryl A Nowson; Claire Margerison; Mandy G Frame; Bahtiyar Kaymakci; John D Wark

48

Monozygotic twins concordant and discordant for DCD: two sides to the story.  

PubMed

Being an identical twin does not necessarily mean having identical perceptions of family functioning, nor of the twin relationship. Using the co-twin control design, the aim of this study was to explore perceptions of family dynamics and the twin relationship in monozygotic (MZ) twins discordant and concordant for Developmental Coordination Disorder (DCD). It was hypothesized that, as has been found in twins discordant for cerebral palsy, twins without DCD would perceive family functioning as less healthy than would their co-twins with DCD. It was also hypothesized that the twin relationship would be regarded generally as mutually supportive. Questionnaire data on 866 sets of MZ twins aged 6 to 17 years were used to identify seven sets discordant, and two sets concordant for DCD. Quantitative (General Functioning Scale of the Family Assessment Device - FAD), and qualitative (semi-structured interview) measures were used to assess family dynamics and the twin relationship. In discordant sets, six of seven twins without DCD rated family functioning at a less healthy level than did their co-twins with DCD. All twins in the DCD concordant sets rated their family functioning at a healthy level. From the semi-structured interviews, emergent themes included friendship, support, minimal sibling rivalry, and minor difficulties. It was concluded that, overall, the twin relationship was regarded as close and mutually supportive, with an ambivalent polarity between the best and most difficult aspects of being an identical twin. Implications for research, policy and clinical practice are discussed. PMID:21314259

Pearsall-Jones, Jillian G; Piek, Jan P; Steed, Lyndall; McDougall, Megan R; Levy, Florence

2011-02-01

49

Utilizing Twins as Controls for Non-Twin Case-Materials in Genome Wide Association Studies  

PubMed Central

Twin registries around the globe have collected DNA samples from large numbers of monozygotic and dizygotic twins. The twin sample collections are frequently used as controls in disease-specific studies together with non-twins. This approach is unbiased under the hypothesis that twins and singletons are comparable in terms of allele frequencies; i.e. there are no genetic variants associated with being a twin per se. To test this hypothesis we performed a genome-wide association study comparing the allele frequency of 572,352 single nucleotide polymorphisms (SNPs) in 1,413 monozygotic (MZ) and 5,451 dizygotic (DZ) twins with 3,720 healthy singletons. Twins and singletons have been genotyped using the same platform. SNPs showing association with being a twin at P-value < 1 × 10-5 were selected for replication analysis in 1,492 twins (463 MZ and 1,029 DZ) and 1,880 singletons from Finland. No SNPs reached genome-wide significance (P-value < 5 × 10-8) in the main analysis combining MZ and DZ twins. In a secondary analysis including only DZ twins two SNPs (rs2033541 close to ADAMTSL1 and rs4149283 close to ABCA1) were genome-wide significant after meta-analysis with the Finnish population. The estimated proportion of variance on the liability scale explained by all SNPs was 0.08 (P-value=0.003) when MZ and DZ were considered together and smaller for MZ (0.06, P-value=0.10) compared to DZ (0.09, P-value=0.003) when analyzed separately. In conclusion, twins and singletons can be used in genetic studies together with general population samples without introducing large bias. Further research is needed to explore genetic variances associated with DZ twinning. PMID:24340086

Ganna, Andrea; Ortega-Alonso, Alfredo; Havulinna, Aki; Salomaa, Veikko; Kaprio, Jaakko; Pedersen, Nancy L.; Sullivan, Patrick F.; Ingelsson, Erik; Hultman, Christina M.; Magnusson, Patrik K. E.

2013-01-01

50

The sister bonding of duplicated chromosomes  

PubMed Central

Sister chromatid cohesion and separation are two fundamental chromosome dynamics that are essential to equal chromosome segregation during cell proliferation. In this review, I will discuss the major steps that regulate these dynamics during mitosis, with an emphasis on vertebrate cells. The implications of these machineries outside of sister chromatid cohesion and separation are also discussed. PMID:21497666

Zou, Hui

2011-01-01

51

Phocomelia and additional anomalies in two sisters  

Microsoft Academic Search

Two daughters of non consanguineous normal parents had phocomelia of both lower extremities with 4 toed feet. The older sister also had phocomelia of the left upper extremity with 5 finger rays; she died immediately after birth. Autopsy disclosed a congenital diaphragmatic hernia, common mesentery and agenesis of the gallbladder, and normal female genitalia. In addition, the younger sister showed

A. Schinzel

1990-01-01

52

Cohesin: functions beyond sister chromatid cohesion.  

PubMed

Faithful segregation of chromosomes during mitosis and meiosis is the cornerstone process of life. Cohesin, a multi-protein complex conserved from yeast to human, plays a crucial role in this process by keeping the sister chromatids together from S-phase to anaphase onset during mitosis and meiosis. Technological advancements have discovered myriad functions of cohesin beyond its role in sister chromatid cohesion (SCC), such as transcription regulation, DNA repair, chromosome condensation, homolog pairing, monoorientation of sister kinetochore, etc. Here, we have focused on such functions of cohesin that are either independent of or dependent on its canonical role of sister chromatid cohesion. At the end, human diseases associated with malfunctioning of cohesin, albeit with mostly unperturbed sister chromatid cohesion, have been discussed. PMID:23831059

Mehta, Gunjan D; Kumar, Ravinder; Srivastava, Sanjeeva; Ghosh, Santanu Kumar

2013-08-01

53

Monozygotic twins discordant for constitutive BRCA1 promoter methylation, childhood cancer and secondary cancer  

PubMed Central

We describe monozygotic twins discordant for childhood leukemia and secondary thyroid carcinoma. We used bisulfite pyrosequencing to compare the constitutive promoter methylation of BRCA1 and several other tumor suppressor genes in primary fibroblasts. The affected twin displayed an increased BRCA1 methylation (12%), compared with her sister (3%). Subsequent bisulfite plasmid sequencing demonstrated that 13% (6 of 47) BRCA1 alleles were fully methylated in the affected twin, whereas her sister displayed only single CpG errors without functional implications. This between-twin methylation difference was also found in irradiated fibroblasts and untreated saliva cells. The BRCA1 epimutation may have originated by an early somatic event in the affected twin: approximately 25% of her body cells derived from different embryonic cell lineages carry one epigenetically inactivated BRCA1 allele. This epimutation was associated with reduced basal protein levels and a higher induction of BRCA1 after DNA damage. In addition, we performed a genome-wide microarray analysis of both sisters and found several copy number variations, i.e., heterozygous deletion and reduced expression of the RSPO3 gene in the affected twin. This monozygotic twin pair represents an impressive example of epigenetic somatic mosaicism, suggesting a role for constitutive epimutations, maybe along with de novo genetic alterations in recurrent tumor development. PMID:22207351

Galetzka, Danuta; Hansmann, Tamara; El Hajj, Nady; Weis, Eva; Irmscher, Benjamin; Ludwig, Marco; Schneider-Ratzke, Brigitte; Kohlschmidt, Nicolai; Beyer, Vera; Bartsch, Oliver; Zechner, Ulrich; Spix, Claudia; Haaf, Thomas

2012-01-01

54

Twin Jet  

NASA Technical Reports Server (NTRS)

Many subsonic and supersonic vehicles in the current fleet have multiple engines mounted near one another. Some future vehicle concepts may use innovative propulsion systems such as distributed propulsion which will result in multiple jets mounted in close proximity. Engine configurations with multiple jets have the ability to exploit jet-by-jet shielding which may significantly reduce noise. Jet-by-jet shielding is the ability of one jet to shield noise that is emitted by another jet. The sensitivity of jet-by-jet shielding to jet spacing and simulated flight stream Mach number are not well understood. The current experiment investigates the impact of jet spacing, jet operating condition, and flight stream Mach number on the noise radiated from subsonic and supersonic twin jets.

Henderson, Brenda; Bozak, Rick

2010-01-01

55

All in the Family: The Sister Study  

MedlinePLUS

Skip Navigation Bar Home Current Issue Past Issues All in the Family: The Sister Study Past Issues / ... that may ultimately eliminate this dreaded disease. We all know that breast cancer does not discriminate. Whether ...

56

SCE (SISTER CHROMATID EXCHANGES) ANALYSIS IN LYMPHOCYTES  

EPA Science Inventory

Expectations are high that sister chromatid exchange analyses in lymphocytes removed from individuals in various occupational settings may serve as monitors of preventable hazardous chemical exposures in much the same way that chromosome aberration analyses have been useful for d...

57

Eruptive history of South Sister, Oregon Cascades  

NASA Astrophysics Data System (ADS)

South Sister is southernmost and highest of the Three Sisters, three geologically dissimilar stratovolcanoes that together form a spectacular 20 km reach along the Cascade crest in Oregon. North Sister is a monotonously mafic edifice as old as middle Pleistocene, Middle Sister a basalt-andesite-dacite cone built between 48 and 14 ka, and South Sister is a basalt-free edifice that alternated rhyolitic and intermediate modes from 50 ka to 2 ka (largely contemporaneous with Middle Sister). Detailed mapping, 330 chemical analyses, and 42 radioisotopic ages show that the oldest exposed South Sister lavas were initially rhyolitic ~ 50 ka. By ~ 37 ka, rhyolitic lava flows and domes (72-74% SiO 2) began alternating with radially emplaced dacite (63-68% SiO 2) and andesite (59-63% SiO 2) lava flows. Construction of a broad cone of silicic andesite-dacite (61-64% SiO 2) culminated ~ 30 ka in a dominantly explosive sequence that began with crater-forming andesitic eruptions that left fragmental deposits at least 200 m thick. This was followed at ~ 27 ka by growth of a steeply dipping summit cone of agglutinate-dominated andesite (56-60.5% SiO 2) and formation of a summit crater ~ 800 m wide. This crater was soon filled and overtopped by a thick dacite lava flow and then by > 150 m of dacitic pyroclastic ejecta. Small-volume dacite lavas (63-67% SiO 2) locally cap the pyroclastic pile. A final sheet of mafic agglutinate (54-56% SiO 2) - the most mafic product of South Sister - erupted from and drapes the small (300-m-wide) present-day summit crater, ending a summit-building sequence that lasted until ~ 22 ka. A 20 kyr-long-hiatus was broken by rhyolite eruptions that produced (1) the Rock Mesa coulee, tephra, and satellite domelets (73.5% SiO 2) and (2) the Devils Chain of ~ 20 domes and short coulees (72.3-72.8% SiO 2) from N-S vent alignments on South Sister's flanks. The compositional reversal from mafic summit agglutinate to recent rhyolites epitomizes the frequently changing compositional modes of the South Sister locus throughout its lifetime. South Sister is part of a reach of the Cascades unusually active in the last 50 kyr, characterized by high vent density, N-S vent alignments, and numerous eruptive units of true rhyolite (? 72% SiO 2) that distinguishes it from much of the Quaternary Cascade arc; these are eruptive expressions of the complex confluence of arc and intraplate magmatic-tectonic regimes.

Fierstein, Judy; Hildreth, Wes; Calvert, Andrew T.

2011-10-01

58

Eruptive history of South Sister, Oregon Cascades  

USGS Publications Warehouse

South Sister is southernmost and highest of the Three Sisters, three geologically dissimilar stratovolcanoes that together form a spectacular 20km reach along the Cascade crest in Oregon. North Sister is a monotonously mafic edifice as old as middle Pleistocene, Middle Sister a basalt-andesite-dacite cone built between 48 and 14ka, and South Sister is a basalt-free edifice that alternated rhyolitic and intermediate modes from 50ka to 2ka (largely contemporaneous with Middle Sister). Detailed mapping, 330 chemical analyses, and 42 radioisotopic ages show that the oldest exposed South Sister lavas were initially rhyolitic ~50ka. By ~37ka, rhyolitic lava flows and domes (72-74% SiO2) began alternating with radially emplaced dacite (63-68% SiO2) and andesite (59-63% SiO2) lava flows. Construction of a broad cone of silicic andesite-dacite (61-64% SiO2) culminated ~30ka in a dominantly explosive sequence that began with crater-forming andesitic eruptions that left fragmental deposits at least 200m thick. This was followed at ~27ka by growth of a steeply dipping summit cone of agglutinate-dominated andesite (56-60.5% SiO2) and formation of a summit crater ~800m wide. This crater was soon filled and overtopped by a thick dacite lava flow and then by >150m of dacitic pyroclastic ejecta. Small-volume dacite lavas (63-67% SiO2) locally cap the pyroclastic pile. A final sheet of mafic agglutinate (54-56% SiO2) - the most mafic product of South Sister - erupted from and drapes the small (300-m-wide) present-day summit crater, ending a summit-building sequence that lasted until ~22ka. A 20kyr-long-hiatus was broken by rhyolite eruptions that produced (1) the Rock Mesa coulee, tephra, and satellite domelets (73.5% SiO2) and (2) the Devils Chain of ~20 domes and short coulees (72.3-72.8% SiO2) from N-S vent alignments on South Sister's flanks. The compositional reversal from mafic summit agglutinate to recent rhyolites epitomizes the frequently changing compositional modes of the South Sister locus throughout its lifetime. South Sister is part of a reach of the Cascades unusually active in the last 50kyr, characterized by high vent density, N-S vent alignments, and numerous eruptive units of true rhyolite (? 72% SiO2) that distinguishes it from much of the Quaternary Cascade arc; these are eruptive expressions of the complex confluence of arc and intraplate magmatic-tectonic regimes.

Fierstein, J.; Hildreth, W.; Calvert, A.T.

2011-01-01

59

The Amoeba Sisters YouTube Videos  

NSDL National Science Digital Library

The Amoeba Sisters strive to facilitate curiosity and engagement by making biology both humorous and meaningful. The videos use real world examples and silly cartoons to demystify difficult biology concepts, such as cell anatomy, homeostasis, enzymes, and biomolecules. A new video is released weekly. The creators are sisters who both work in education. One is a high school biology teacher who found these videos made biology more approachable and easier to comprehend.

Sisters, The A.

2014-04-04

60

Having Twins? How to Stay Healthy  

MedlinePLUS

... stomach at all times can help take the edge off of the nausea. Low-fat yogurt, fruit, smoothies, crackers, and protein shakes are all good snack options. In addition to the extra calories, it is important to sip on water throughout the day. Keeping well hydrated may drive ...

61

Twin Prime Sieve  

E-print Network

A sieve is constructed for ordinary twin primes of the form 6m+/-1 that are characterized by their twin rank m. It has no parity problem. Non-rank numbers are identified and counted using odd primes p>=5. Twin- and non-ranks make up the set of positive integers. Regularities of non-ranks allow gathering information on them to obtain a Legendre-type formula for the number of twin-ranks near primorial arguments.

H. J. Weber

2012-03-23

62

[Interlocking of twins].  

PubMed

We report about a very rare case of locked twins in cephalic presentations. A difficult forceps was necessary. In spite of cleidotomy and pushing the other twin out of the pelvis the fetus was in a deep distress and the resuscitation was unsuccessful. The second twin followed spontaneously, alive and well. PMID:2618205

Unzeitig, V; Uher, M

1989-01-01

63

Phocomelia and additional anomalies in two sisters.  

PubMed

Two daughters of non-consanguineous normal parents had phocomelia of both lower extremities with 4-toed feet. The older sister also had phocomelia of the left upper extremity with 5 finger rays; she died immediately after birth. Autopsy disclosed a congenital diaphragmatic hernia, common mesentery and agenesis of the gallbladder, and normal female genitalia. In addition, the younger sister showed a bony skull defect, diastasis recti, agenesis of the uterus and agenesis or atresia of the vagina, hypoplasia of the sacrum and hypo/dysplasia of the pelvic bones. Her growth and mental development were normal. The patterns of anomalies of the two sisters do not fit into any of the syndromes featuring phocomelia; there was no prenatal exposure to thalidomide or any other possible teratogen. PMID:2338339

Schinzel, A

1990-05-01

64

Twin Paradox Program  

NSDL National Science Digital Library

The Twin Paradox program displays the effect of time dilation on a moving twin as seen from a stationary twin. In the default scenario the light signals sent from the moving twin are depicted using a spacetime diagram and are shown as seen in the stationary twinâs reference frame (the Home Frame). The sliders can be used to change the twinâs trip distance and her trip speed relative to the stationary twin. Twin Paradox is an Open Source Physics program written for the teaching of special relativity. It is distributed as a ready-to-run (compiled) Java archive. Double clicking the sr_twin.jar file will run the program if Java is installed. Other special relativity programs are also available. They can be found by searching ComPADRE for Open Source Physics, OSP, or Relativity.

Simov, Kiril; Christian, Wolfgang

2008-05-30

65

Genomics of ageing in twins.  

PubMed

Ageing is a complex multifactorial process, reflecting the progression of all degenerative pathways within an organism. Due to the increase of life expectancy, in recent years, there is a pressing need to identify early-life events and risk factors that determine health outcomes in later life. So far, genetic variation only explains ~20-25 % of the variability of human survival to age 80+. This clearly implies that other factors (environmental, epigenetic and lifestyle) contribute to lifespan and the rate of healthy ageing within an individual. Twin studies in the past two decades proved to be a very powerful tool to discriminate the genetic from the environmental component. The aim of this review is to describe the basic concepts of the twin study design and to report some of the latest studies in which high-throughput technologies (e.g. genome/epigenome-wide assay, next generation sequencing, MS metabolic profiling) combined with the classical twin design have been applied to the analysis of novel 'omics' to further understand the molecular mechanisms of human ageing. PMID:24984159

Mangino, Massimo

2014-11-01

66

Complete mole coexistent with a twin fetus  

Microsoft Academic Search

Introduction  Complete hydatiforme mole with coexisting live fetus (CMCF) is a rare entity. Management for this rare twin pregnancy still\\u000a remains undetermined. We report the delivery of a healthy baby coexisting with complete mole as twins. There was no other\\u000a complication during or after the pregnancy.\\u000a \\u000a \\u000a \\u000a Case report  A 30-year-old multiparous woman was first time assessed in the antenatal outpatient department of

Mehmet Albayrak; Alev Özer; Ömer Faruk Demir; Serdar Özer; Salim Erkaya

2010-01-01

67

Long term outcome of twin-twin transfusion syndrome  

Microsoft Academic Search

AIMSTo compare the perinatal mortality and morbidity of infants with twin-twin transfusion syndrome (TTTS) with those of gestation matched twin controls and to assess the neurodevelopmental outcome of surviving twins with TTTS.METHODSA cohort of 17 consecutive pregnancies with TTTS was enrolled over three years together with gestation matched twin pregnancies unaffected by TTTS. Serial amnioreduction for the TTTS pregnancies was

R B Cincotta; P H Gray; G Phythian; Y M Rogers; F Y Chan

2000-01-01

68

SISTER CHROMATID EXCHANGES IN MAMMALIAN MEIOTIC CHROMOSOMES  

EPA Science Inventory

Very little is known about sister chromatid exchanges (SCEs) in meiotic cells--only that they occur (1) and reveal frequency and distribution patterns apparently unaffected by cross-over (CO) exchange conditions in those cells; (2) unfortunately, the number of studies from which ...

69

Sister chromatid cohesion control and aneuploidy.  

PubMed

Apart from a personal tragedy, could Down syndrome, cancer and infertility possibly have something in common? Are there links between a syndrome with physical and mental problems, a tumor growing out of control and the incapability to reproduce? These questions can be answered if we look at the biological functions of a protein complex, named cohesin, which is the main protagonist in the regulation of sister chromatid cohesion during chromosome segregation in cell division. The establishment, maintenance and removal of sister chromatid cohesion is one of the most fascinating and dangerous processes in the life of a cell. Errors in the control of sister chromatid cohesion frequently lead to cell death or aneuploidy. Recent results showed that cohesins also have important functions in non-dividing cells, revealing new, unexplored roles for these proteins in human syndromes, currently known as cohesinopathies. In the last 10 years, we have improved our understanding of the molecular mechanisms of the cohesin and cohesin-interacting proteins regulating the different events of sister chromatid cohesion during cell division in mitosis and meiosis. PMID:21252490

Barbero, J L

2011-01-01

70

Delayed interval delivery after intrauterine infection and immature birth of twin 1 — a case report and literature review  

Microsoft Academic Search

We report a case of delayed interval delivery in a twin pregnancy complicated by rupture of membranes, intrauterine infection and birth of one twin at 21 weeks gestation. Tocolysis combined with antibiotics and corticosteroids successfully prolonged pregnancy for 73 days, allowing the second twin to mature and reach viability. At 31.5 weeks gestation, a 1890 g healthy male neonate was

Marieke W. de Jong; Ingrid M. Pinas; Jim van Eijck

1995-01-01

71

Twins discordant for myositis and systemic lupus erythematosus show markedly enriched autoantibodies in the affected twin supporting environmental influences in pathogenesis  

PubMed Central

Background Studies of twin pairs discordant for autoimmune conditions provide a unique opportunity to explore contributing factors triggered by complex gene-environment interactions. Methods In this cross-sectional study, thirty-one monozygotic or dizygotic twin pairs discordant for myositis or systemic lupus erythematosus (SLE), along with matched healthy controls were evaluated for antibodies against a panel of 21 autoantigens. Results Autoantibody profiling revealed that 42% of the affected twins showed significant seropositivity against autoantigens in the panel. In many of these affected twins, but none of healthy controls, there were high levels of autoantibodies detected against two or more autoantigens commonly seen in systemic autoimmune diseases including Ro52, Ro60, RNP-70 K and/or RNP-A. In contrast, only 10% (3/31) of the unaffected twins showed seropositivity and these immunoreactivities were against single autoantigens not seen in systemic autoimmune diseases. While no significant differences in autoantibodies were detected between the affected or unaffected twins against thyroid peroxidase, transglutaminase and several cytokines, 23% of the affected twins with myositis showed autoantibodies against the gastric ATPase. Analysis of the monozygotic twins separately also revealed a higher frequencies of autoantibodies in the affected twins compared to the unaffected twins (P?=?0.046). Lastly, clinical analysis of both the affected monozygotic and dizygotic twins revealed that the autoantibody seropositive affected twins had a greater global disease activity score compared to seronegative affected twins (P?=?0.019). Conclusion The findings of significantly more autoantibodies in the affected twins with myositis and SLE compared to the unaffected twins are consistent with potential non-genetic factors playing a role in autoantibody production and pathogenesis of these autoimmune disorders. PMID:24602337

2014-01-01

72

Malaysian Twin Registry.  

PubMed

The National Malaysian Twin Registry was established in Royal College of Medicine, Perak, University Kuala Lumpur (UniKL) in June 2008 through a grant provided by UniKL. The general objective is to facilitate scientific research involving participation of twins and their family members in order to answer questions of health and wellbeing relevant to Malaysians. Recruitment is done via mass media, poster, and pamphlets. We now have 266 adult and 204 children twins registered. Several research projects including reproductive health study of twins and the role of co-bedding on growth and development of children are carried out. Registry holds annual activities for twins and seeks to provide health-related information for twins. We seek international collaboration. PMID:23110917

Jahanfar, Shayesteh; Jaffar, Sharifah Halimah

2013-02-01

73

Crocodile Talk: Attributions of Incestuously Abused and Nonabused Sisters.  

ERIC Educational Resources Information Center

This qualitative study analyzed the retrospective attributions of adult sisters (five abused sister dyads, and five abused and nonabused sister dyads) who grew up in incestuous families. It examined the attributions of subjects regarding the general sibling group; victim selection and nonselection; and attributions regarding jealousy, protection,…

Monahan, Kathleen

1997-01-01

74

The Hungarian Twin Registry.  

PubMed

The first Hungarian Twin Registry was established in Budapest in 1970 through the mandatory reporting of multiple-births. In the 1980s a second, volunteer adult registry was also founded. Unfortunately, both registries ceased to exist in the 1990s. Efforts started in 2006 to revive a Hungarian twin registry. The team spearheading this effort reports here on this progress. Currently, the voluntary Hungarian Twin Registry consists of 310 adult twin pairs and multiplets. Current research focuses on cardiovascular and respiratory health and yielded multiple awards and publications. Efforts are on the way to expand into social, psychological, and obesity studies. PMID:23084033

Littvay, Levente; Métneki, Julia; Tárnoki, Adám D; Tárnoki, Dávid L

2013-02-01

75

Healthy Water, Healthy People.  

ERIC Educational Resources Information Center

Describes a hands-on activity, Hitting the Mark, which is found in the "Healthy Water, Healthy People Water Quality Educators Guide" in terms of its objectives, materials, background, procedures, activities, and assessment. (KHR)

Etgen, John

2002-01-01

76

Basal Twinning of Hematite  

NASA Astrophysics Data System (ADS)

When two crystals share a plane, there is a twinning composition plane. The result is an intergrowth of two separate crystals in a symmetrical manner. Crystallographers classify twinned crystals by a number of twin laws. These twin laws are specific to the crystal system. The type of twinning can be a diagnostic tool in mineral identification and characterization. Many twin laws cannot be recognized in ordinary optical analysis. So, the advent of diffraction techniques to describe punctual crystallographic orientation facilitated the identification of many twinned crystals in rocks. Samples containing hematite of the Quadrilátero Ferrífero, Minas Gerais, Brazil, were analyzed by EBSD technique. Crystallographic orientation data were obtained from automatically indexed EBSD patterns collected on a JEOL JSM-5510. EBSD analysis was carried out on thin sections cut perpendicular to the foliation (XZ plane) and parallel to the stretching lineation (X-direction). Thin sections were polished before EBSD analysis. EBSD patterns were indexed using CHANNEL 5 software from HKL Technology, Oxford Instruments. The resulting data are presented in form of pole figures (upper hemisphere, equal angle, stereographic projection) and of colour-coded maps using Coincidence Site Lattice (? 3) and Twin Boundaries Components. Through electron backscatter diffraction analysis of hematite grains was possible to detect twin boundaries similar to Dauphiné twinning in quartz that is not described for hematite. Dauphiné twinning in trigonal ?-quartz consists of a 60° rotation around the c-axis resulting in a reversal of the crystallographic positive and negative forms (Frondel 1962). As both minerals show similar symmetry, the same mechanism can be described for hematite in this analysis. The basal twinning of hematite developed pervasively during the incipient stage of deformation. This paper investigates the relationships between this kind of twinning, deformation conditions and microstructural modifications in hematite grains. The results show that the presence of twins exerts an important role in the distribution of the intracrystalline plastic deformation in hematite, as well as in the activation of different sets of slip systems. We estimate that basal twin bands can be preferred sites for dynamic recrystallization.

Gonçalves, Fábio; Lagoeiro, Leonardo; Barbosa, Paola

2013-04-01

77

Effect of borax on immune cell proliferation and sister chromatid exchange in human chromosomes  

PubMed Central

Background Borax is used as a food additive. It becomes toxic when accumulated in the body. It causes vomiting, fatigue and renal failure. Methods The heparinized blood samples from 40 healthy men were studied for the impact of borax toxicity on immune cell proliferation (lymphocyte proliferation) and sister chromatid exchange in human chromosomes. The MTT assay and Sister Chromatid Exchange (SCE) technic were used in this experiment with the borax concentrations of 0.1, 0.15, 0.2, 0.3 and 0.6 mg/ml. Results It showed that the immune cell proliferation (lymphocyte proliferation) was decreased when the concentrations of borax increased. The borax concentration of 0.6 mg/ml had the most effectiveness to the lymphocyte proliferation and had the highest cytotoxicity index (CI). The borax concentrations of 0.15, 0.2, 0.3 and 0.6 mg/ml significantly induced sister chromatid exchange in human chromosomes (P < 0.05). Conclusion Borax had effects on immune cell proliferation (lymphocyte proliferation) and induced sister chromatid exchange in human chromosomes. Toxicity of borax may lead to cellular toxicity and genetic defect in human. PMID:19878537

Pongsavee, Malinee

2009-01-01

78

Gestational age in twins  

Microsoft Academic Search

Dubowitz et al. have offered a scoring system for estimating the gestational age of newborn babies. If the system is applied to twin pairs, the heavier twin is generally estimated to have a greater gestational age than the lighter one. Previously this has been interpreted as a flaw in the scoring system. However, it may well be that in some

W H James

1980-01-01

79

Rotational Twin Paradox  

NASA Astrophysics Data System (ADS)

Two twins settle on a massive spherical planet at a train station S. Let's consider that each twin has an accompanying clock, and the two clocks are synchronized. One twin T1 remains in the train station, while the other twin T2 travels at a uniform high speed with the train around the planet (on the big circle of the planet) until he gets back to the same train station S. Assume the planet is not rotating. Since the planet is massive, we can consider that on a very small part on its surface the train rail road is linear, so the train is in a linear uniform motion. The larger is the planet's radius the more the rail road approaches a linear trajectory. Because the GPS clocks are alleged to be built on the Theory of Relativity, one can consider the twin T2 train's circular trajectory alike the satellite's orbit. In addition, the gravitation is the same for the reference frames of T1 and T2. Each twin sees the other twin as traveling, therefore each twin finds the other one has aged slower than him. Thus herein we have a relativistic symmetry. When T2 returns to train station S, he finds out that he is younger than T1 (therefore asymmetry). Thus, one gets a contradiction between symmetry and asymmetry.

Smarandache, Florentin

2012-10-01

80

Papillary thyroid cancer in identical adolescent twins with osteogenesis imperfecta and Hashimoto's thyroiditis: is there a genetic link?  

PubMed

The relationship between Hashimoto's thyroiditis (HT) and papillary thyroid cancer (PTC) remains controversial. Researchers have identified multiple genes that could put patients with HT at risk for PTC. None are related to osteogenesis imperfecta (OI). We present identical twin sisters with OI who developed PTC in the setting HT. PMID:25197868

Diegidio, Paul; Kolok, Damon; Brown, Whitney; Camps, Juan I

2014-09-01

81

An Investigation of Exceptional Twins.  

ERIC Educational Resources Information Center

The author, herself a mother of twins, reviews research on exceptional twins. She considers reasons for fascination with twins and comments upon important advances in technology. Current research in Indianapolis to measure cognitive, perceptual, personality, and chromosome patterns of twins is described. Differences in the makeup of identical and…

Crismore, Avon

82

TwinDocs  

NSDL National Science Digital Library

TwinDocs is a novel way to upload documents to a personal storage device quickly. Visitors need to sign up for a free account and then they can get started. The TwinDocs application gives users the ability to access any document remotely from technology such as an iPhone, iPad, or Android device. The free version of TwinDocs gives users 1GB of storage and the ability to store 25 documents a month. This version is compatible with all operating systems.

2013-02-15

83

Sister Mary Emil Penet, I.H.M.: Founder of the Sister Formation Conference  

ERIC Educational Resources Information Center

Mary Emil Penet, I.H.M., (1916-2001) used her talents and charisma to shape the first national organization of American women religious, the Sister Formation Conference (SFC; 1954-1964), facilitating the integrated intellectual, spiritual, psychological, and professional development of vowed women religious. In the decade preceding Vatican II, her…

Glisky, Joan

2006-01-01

84

Differential giemsa staining of sister chromatids and the study of sister chromatid exchanges without autoradiography  

Microsoft Academic Search

Chinese hamster ovary cells grown for two rounds of DNA replication in the presence of BrdUrd contain sister chromatids that fluoresce differentially when stained with Hoechst 33258. If such fluorescent treatments are followed by incubation in 2 X SSC or water at 62° C and staining in 3% Giemsa, the chromosomes now contain one dark (unifilarly substituted) chromatid and one

Sheldon Wolff; Paul Perry

1974-01-01

85

Progeria in twins  

Microsoft Academic Search

A pair of male monozygotic twins, both affected by progeria is described. The concordance in this manifestation suggests a genetic aetiology and other evidence indicates the implication of autosomal recessive factors; the chromosomes of these patients show no detectable abnormalities.

Judith Viégas; P. L. R. Souza; F. M. Salzano

1974-01-01

86

The Fetal Heart in Twin-to-Twin Transfusion Syndrome.  

PubMed

Twin-to-twin transfusion syndrome is a severe complication occurring in 10% of monochorionic twin pregnancies. The disease is usually explained as due to an intrauterine imbalance in intertwin blood exchange, which leads to a volume depleted-donor twin and an overfilled recipient twin. The recipient has signs of cardiac dysfunction, which can be measured using echocardiography or blood and amniotic fluid derived biomarkers. Whereas cardiac dysfunction typically progresses in pregnancies treated with amniodrainage, it usually disappears within a few weeks after fetoscopic laser coagulation of the connecting intertwin anastomoses. Nevertheless, recipients remain at a increased risk of pulmonary stenosis. In this paper, we summarize the cardiac alterations in twin-to-twin transfusion syndrome, describe the changes seen after fetal therapy, list the newly proposed staging systems based on fetal cardiac function, and make recommendations about the use of fetal echocardiography in the evaluation and followup of pregnancies complicated by twin-to-twin transfusion syndrome. PMID:20811613

Van Mieghem, Tim; Lewi, Liesbeth; Gucciardo, Léonardo; Dekoninck, Philip; Van Schoubroeck, Dominique; Devlieger, Roland; Deprest, Jan

2010-01-01

87

Twin Studies of Behavior  

Microsoft Academic Search

In the age of molecular genetics some commentators have questioned whether twin studies will continue to be a useful tool\\u000a for studying genetic influences on behavior. Many of us think the answer is yes (Bouchard & Propping, 1993). Work with monozygotic\\u000a twins reared apart provides an imperfect, but nevertheless powerful window on the direct influence of genes on whole organisms.

Thomas J. Bouchard

88

Dogs discriminate identical twins.  

PubMed

Earlier studies have shown variation among experimental attempts to establish whether human monozygotic twins that are genetically identical also have identical individual scents. In none of the cases were the dogs able to distinguish all the individual scents of monozygotic twins living in the same environment if the scents were presented to them separately. Ten specially trained police German Shepherd dogs of three Czech Republic Police Regional Headquarters were used for scent identification in our study. The dogs were supposed to match scents of two monozygotic pairs (5 and 7 years old) and two dizygotic twin pairs (8 and 13 years old). Scents were collected on cotton squares stored in glass jars. Dog handlers were blind to the experiment details. In each trial (line-up), one scent was used as a starting scent and the dog was then sent to determine if any of the 7 presented glass jars contained a matching scent. Scents of children of similar ages were used as distractors. In the matching procedure, the dogs matched correctly the scent of one twin with the other, as well as two scents collected from every single identical and non-identical twin to prove their efficacy and likewise, the presence of the matching twin scent in any given glass jar. All dogs in all trials distinguished correctly the scents of identical as well as non-identical twins. All dogs similarly matched positively two scents collected from the same individuals. Our findings indicated that specially trained German Shepherd dogs are able to distinguish individual scents of identical twins despite the fact that they live in the same environment, eat the same food and even if the scents are not presented to them simultaneously. PMID:21698282

Pinc, Ludvík; Bartoš, Lud?k; Reslová, Alice; Kotrba, Radim

2011-01-01

89

The Lehman Sisters Hypothesis: an exploration of literature and bankers.  

E-print Network

??abstractThis article tests the Lehman Sisters Hypothesis in two complementary, although incomplete ways. It reviews the diverse empirical literature in behavioural, experimental, and neuroeconomics as… (more)

I.P. van Staveren (Irene)

2012-01-01

90

Twin relationships: A comparison across monozygotic twins, dizygotic twins, and nontwin siblings in early childhood  

Microsoft Academic Search

Twin relationships remain understudied despite the increasing prevalence of twinning and the unique influence it entails for individual development and family functioning. The current study assessed closeness, conflict, dependence, and rivalry within 1281 pairs of 3-year-old twins via maternal reports. Relationship quality was compared based on the twins' zygosity and dyadic sex-composition. As expected, monozygotic (genetically identical) twins were perceived

Keren Fortuna; Ira Goldner; Ariel Knafo

2010-01-01

91

Intravenous iron administration together with parenteral nutrition to very preterm Jehovah's Witness twins.  

PubMed

Preterm twin sisters (monozygotic) were born at gestational age 27?weeks and 5?days with birth weights of 935 and 735?g. They were admitted to our neonatal intensive care unit for a period of 1?month. Their parents were Jehovah's Witnesses and refused blood transfusion for their preterm daughters. Subcutaneous erythropoietin and intravenous iron were given as a prophylactic to avoid anaemia. PMID:24891477

Poorisrisak, Porntiva; Schroeder, Allan Mikael; Greisen, Gorm; Zachariassen, Gitte

2014-01-01

92

Fetal Limb Ischaemia in Twin-to-Twin Transfusion Syndrome  

PubMed Central

Objective. To describe the rare association between prenatal vascular limb occlusion and twin-to-twin transfusion syndrome. The Case. A woman with severe twin-to-twin transfusion syndrome was treated with fetoscopic laser ablation at 19-week gestation. At 27 weeks, the twins were delivered by an emergency caesarean section. The right arm of twin 1, the recipient twin, was noted to be “ischaemic” and was later amputated. Conclusion. This case is unusual in that it affected the upper limb and there was no evidence of polycythaemia, which is a suggested pathological mechanism. It was initially thought that the limb damage was due to the laser ablation, but after discussion with the fetal medicine team vascular limb occlusion in association with twin-to-twin transfusion syndrome was considered. Limb ischaemia is a serious complication of twin-to-twin transfusion syndrome and is unrelated to any form of fetal therapy. Implications. Neonatologists and paediatricians need to be aware of this association as it has medicolegal implications and parents should be counselled as to the possible, albeit rare, occurrence, especially when twin-to-twin transfusion syndrome is of advanced stage at presentation. PMID:24386580

Kilby, Mark

2013-01-01

93

Gestational age in twins.  

PubMed

Dubowitz et al. have offered a scoring system for estimating the gestational age of newborn babies. If the system is applied to twin pairs, the heavier twin is generally estimated to have a greater gestational age than the lighter one. Previously this has been interpreted as a flaw in the scoring system. However, it may well be that in some twin pairs the gestational ages are slightly different and that therefore, the heavier twin would be expected to have a greater gestational age. Such cases would arise through superfecundation (the formation of two zygotes from different coitions). Superfecundation can be proved only in rare case (those with two fathers). It can be argued that the rarity of such cases is accounted for by the rarity with which women expose themselves to the risk of bearing such twins (and by the improbability of detection), rather than by the rarity of superfecundation. It is inferred that superfecundation by the same man is relatively common and that therefore dizygotic twins quite often have different gestational ages. The scoring system of Dubowitz can be tested for bias by submitting monozygotic pairs to it: the association between weight and estimated gestational age should be absent in such pairs. If the system proves free of such bias, then a finding first reported here will assume some interest: it is that in opposite-sexed twin pairs, the male is significantly more often assessed as having the greater gestational age. It is suggested that this finding should be provisionally accepted as evidence for the hyopthesis that male zygotes are formed earlier than females. PMID:7191240

James, W H

1980-04-01

94

Gestational age in twins.  

PubMed Central

Dubowitz et al. have offered a scoring system for estimating the gestational age of newborn babies. If the system is applied to twin pairs, the heavier twin is generally estimated to have a greater gestational age than the lighter one. Previously this has been interpreted as a flaw in the scoring system. However, it may well be that in some twin pairs the gestational ages are slightly different and that therefore, the heavier twin would be expected to have a greater gestational age. Such cases would arise through superfecundation (the formation of two zygotes from different coitions). Superfecundation can be proved only in rare case (those with two fathers). It can be argued that the rarity of such cases is accounted for by the rarity with which women expose themselves to the risk of bearing such twins (and by the improbability of detection), rather than by the rarity of superfecundation. It is inferred that superfecundation by the same man is relatively common and that therefore dizygotic twins quite often have different gestational ages. The scoring system of Dubowitz can be tested for bias by submitting monozygotic pairs to it: the association between weight and estimated gestational age should be absent in such pairs. If the system proves free of such bias, then a finding first reported here will assume some interest: it is that in opposite-sexed twin pairs, the male is significantly more often assessed as having the greater gestational age. It is suggested that this finding should be provisionally accepted as evidence for the hyopthesis that male zygotes are formed earlier than females. PMID:7191240

James, W H

1980-01-01

95

Twins: A cloning experience.  

PubMed

Drawing upon qualitative interviews with monozygotic (identical) twins sharing 100% of their genes, and with dizygotic (fraternal) twins and singletons as control groups, this paper explores what it means to be genetically identical. (The twins interviewed were from the TwinsUK register in London.) In the context of the ongoing debate on human reproductive cloning, it examines questions such as: To what extent do identical twins perceive their emotional and physical bond to be a result of their genetic makeup? What would they think if they had been deliberately created genetically identical? How would they feel about being genetically identical to a person who was born a few years earlier or later? First, our respondents ascribed no great significance to the role of genes in their understanding of what it means to be identical twins. Second, the opinion that human reproductive cloning would "interfere with nature", or "contradict God's will", was expressed by our respondents exclusively on the abstract level. The more our respondents were able to relate a particular invented cloning scenario to their own life-worlds, the lower the prevalence of the argument. Third, for all three groups of respondents, the scenario of having been born in one of the other groups was perceived as strange. Fourth, the aspect that our respondents disliked about cloning scenarios was the potential motives of the cloners. Without equating monozygotic twins directly with "clones", these results from "naturally" genetically identical individuals add a new dimension to what a future cloning situation could entail: The cloned person might possibly (a) perceive a close physical and emotional connection to the progenitor as a blessing; (b) suffer from preconceptions of people who regard physical likeness as a sign of incomplete individuality; and (c) perceive the idea of not having been born a clone of a particular person as unpleasant. PMID:16876924

Prainsack, Barbara; Spector, Tim D

2006-11-01

96

EarthLabs Meet Sister Corita Kent  

NASA Astrophysics Data System (ADS)

The EarthLabs project provides a framework to enhance high school students' climate literacy and awareness of climate change. The project provides climate science curriculum and teacher professional development, followed by research on students' learning as teachers implement EarthLabs climate modules in the classroom. The professional development targets high school teachers whose professional growth is structured around exposure to current climate science research, data observation collection and analysis. During summer workshops in Texas and Mississippi, teachers work through the laboratories, experiments, and hand-on activities developed for their students. In summer 2013, three graduate students from the University of Texas at Austin Institute for Geophysics with expertise in climate science participated in two weeklong workshops. The graduate students partnered with exemplary teacher leaders to provide scientific content and lead the EarthLabs learning activities. As an experiment, we integrated a visit to the Blanton Museum and an associated activity in order to motivate participants to think creatively, as well as analytically, about science. This exercise was inspired by the work and educational philosophy of Sister Corita Kent. During the visit to the Blanton Museum, we steered participants towards specific works of art pre-selected to emphasize aspects of the climate of Texas and to draw participants' attention to ways in which artists convey different concepts. For example, artists use of color, lines, and symbols conjure emotional responses to imagery in the viewer. The second part of the exercise asked participants to choose a climate message and to convey this through a collage. We encouraged participants to combine their experience at the museum with examples of Sister Corita Kent's artwork. We gave them simple guidelines for the project based on techniques and teaching of Sister Corita Kent. Evaluation results reveal that participants enjoyed the activity and saw its value for enhancing their own appreciation of climate science. However, participants expressed skepticism about using the exercise with their own students. Teachers' perception was that students would not make the same connections that they did. From our perspective and participants' enthusiasm we encourage collaboration between art and science teachers in joint activities that emphasize the link between art and science.

Quartini, E.; Ellins, K. K.; Cavitte, M. G.; Thirumalai, K.; Ledley, T. S.; Haddad, N.; Lynds, S. E.

2013-12-01

97

RESEARCH ARTICLE Continuing inflation at Three Sisters volcanic center,  

E-print Network

rhyolite tephra, pyroclastic flows, lava flows, and lava domes from vents on the volcano's south, southeast not culminate in eruptions. Keywords Three Sisters . South Sister. Cascade Range . Volcanology. Geodesy. Radar Cascade Range is a long-lived center of basaltic to rhyolitic volcanism that includes three large

98

Mouse satellite DNA, centromere structure, and sister chromatid pairing  

Microsoft Academic Search

The experiments described were directed toward understanding relationships between mouse satellite DNA, sister chromatid pairing, and centromere function. Electron microscopy of a large mouse L929 marker chromosome shows that each of its multiple constrictions is coincident with a site of sister chromatid contact and the presence of mouse satellite DNA. However, only one of these sites, the central one, possesses

Lorraine M. Lica; Sandya Narayanswami; Barbara A. Hamkalo

1986-01-01

99

Chronic Idiopathic Neutrophilia in Two Twins  

PubMed Central

Neutrophilia in adults refers to an alteration in the total number of blood neutrophils that is in excess of about 7500 cells/?L. This definition is restrictive in childhood as neutrophil count is age-dependent. Chronic Idiopathic Neutrophilia (CIN) refers to a condition that persists for many years in individuals who appear otherwise healthy. CIN is rarely mentioned in scientific literature and in academic books of hematology; only few words are dedicated to this topic. We report a case study of two twins with CIN followed from the first year of life to 24 years of age. To the best of our knowledge this is the first case report of two twins with CIN followed through a long period of time. We believe that our observation may contribute to better understand and characterize this hematologic abnormality.

Miniero, Roberto; Altomare, Federica; Fusaro, Carla

2014-01-01

100

Allergic colitis in monozygotic preterm twins.  

PubMed

Allergic colitis (AC) typically develops in the first weeks or months of life and is characterized by the presence of red blood in the stools of healthy breastfed or formula fed infants. In this paper, we describe a case of rectal bleeding in monozygotic preterm twins that was resolved with the introduction of a cow's milk protein-free diet (CMPFD). The occurrence of this disorder in monozygotic twins raises the question as to whether the underlying abnormality in the immune regulation, which leads to poor acquisition of tolerance to cow's milk proteins, might be inherited or environmentally acquired. The case also highlights the use of the probiotic Lactobacillus GG (LGG) in the treatment of allergic colitis. PMID:23098248

Baldassarre, Maria Elisabetta; Cappiello, Annarita; Laforgia, Nicola; Vanderhoof, Jon

2013-02-01

101

The Texas Twin Project  

PubMed Central

Socioeconomic position, racial/ethnic minority status, and other characteristics of the macro-environment may be important moderators of genetic influence on a wide array of psychosocial outcomes. Designed to maximize representation of low socioeconomic status families and racial/ethnic minorities, the Texas Twin Project is an on-going study of school-age twins (preschool through 12th grade) enrolled in public schools in the Austin, Texas and Houston, Texas metropolitan areas. School rosters are used to identify twin families from a target population with sizable populations of African-American (18%), Hispanic / Latino (48%), and non-Hispanic White (27%) children and adolescents, over half of whom meet U.S. guidelines for classification as economically disadvantaged. Initial efforts have focused on a large-scale, family-based survey study involving both parent and child reports of personality, psychopathology, physical health, academic interests, parent-child relationships, and aspects of the home environment. In addition, the Texas Twin Project is the basis for an in-laboratory study of adolescent decision-making, delinquency, and substance use. Future directions include geographic expansion of the sample to the entire state of Texas (with a population of over 25 million people) and genotyping of participating twins. PMID:23111007

Harden, K. Paige; Tucker-Drob, Elliot M.; Tackett, Jennifer L.

2013-01-01

102

Branching of twins near an austenite - twinned-martensite interface  

Microsoft Academic Search

We study the role of surface energy in determining twin width near an austenite—twinned-martensite interface. We find that there are two distinct regimes, depending on the relative values of the elastic moduli, surface energy density and grain size. In the first regime the twin width w is constant, of order L , where L is the grain size. In the

Robert V. Kohn; Stefan Müller

1992-01-01

103

A Multidimensional Twin Study of Mental Health in Women  

Microsoft Academic Search

Objective: While researchers have increasing insight into the role of genetic and envi- ronmental factors in the etiology of psychiatric and substance use disorders, they know much less about how such factors influence the dimensions of healthy psychological functioning. Method: In a population-based sample of 794 female-female twin pairs, the authors examined, by using multivariate structural equation modeling, six dimensions

Kenneth S. Kendler; John M. Myers; Michael C. Neale

2000-01-01

104

20 CFR 410.380 - Determination of dependency; parent, brother, or sister.  

Code of Federal Regulations, 2011 CFR

...Determination of dependency; parent, brother, or sister. 410...LUNG BENEFITS (1969- ) Relationship and Dependency § 410.380 Determination of dependency; parent, brother, or sister. An individual who is the miner's parent, brother, or sister...

2011-04-01

105

20 CFR 410.380 - Determination of dependency; parent, brother, or sister.  

Code of Federal Regulations, 2010 CFR

...Determination of dependency; parent, brother, or sister. 410...LUNG BENEFITS (1969- ) Relationship and Dependency § 410.380 Determination of dependency; parent, brother, or sister. An individual who is the miner's parent, brother, or sister...

2010-04-01

106

77 FR 13585 - Three Sisters Irrigation District; Notice of Application Accepted for Filing and Soliciting...  

Federal Register 2010, 2011, 2012, 2013

...Project No. 14364-000] Three Sisters Irrigation District; Notice of Application Accepted...2012. d. Applicant: Three Sisters Irrigation District. e. Name of Project: Three Sisters Irrigation District Hydroelectric Project....

2012-03-07

107

Alloparenting for chimpanzee twins  

PubMed Central

In April 2009, a female chimpanzee named Sango, living in a captive group at the Noichi Zoo, Japan, gave birth to dizygotic male-female twin chimpanzees (male: Daiya, female: Sakura). The extent to which adult group members cared for the twins was investigated using a focal animal sampling method targeting six adults (one male) when the twin chimpanzees were two years old. Data were collected for an average of 6.78?h (SD = 0.79) per focal participant. An unaffiliated female adult of Sango was engaged in parenting Sakura as much as Sango. Given that Sakura was in lesser proximity to Sango than Daiya, Sakura's departures from her mother and her ability to gesture requests might have enabled non-kin adults to provide her care. PMID:25200656

Kishimoto, Takeshi; Ando, Juko; Tatara, Seiki; Yamada, Nobuhiro; Konishi, Katsuya; Kimura, Natsuko; Fukumori, Akira; Tomonaga, Masaki

2014-01-01

108

Alloparenting for chimpanzee twins.  

PubMed

In April 2009, a female chimpanzee named Sango, living in a captive group at the Noichi Zoo, Japan, gave birth to dizygotic male-female twin chimpanzees (male: Daiya, female: Sakura). The extent to which adult group members cared for the twins was investigated using a focal animal sampling method targeting six adults (one male) when the twin chimpanzees were two years old. Data were collected for an average of 6.78?h (SD = 0.79) per focal participant. An unaffiliated female adult of Sango was engaged in parenting Sakura as much as Sango. Given that Sakura was in lesser proximity to Sango than Daiya, Sakura's departures from her mother and her ability to gesture requests might have enabled non-kin adults to provide her care. PMID:25200656

Kishimoto, Takeshi; Ando, Juko; Tatara, Seiki; Yamada, Nobuhiro; Konishi, Katsuya; Kimura, Natsuko; Fukumori, Akira; Tomonaga, Masaki

2014-01-01

109

Monozygotic Twinning and Perinatal Outcomes  

Microsoft Academic Search

\\u000a The choice made by women to delay childbearing until later in their reproductive life coupled with the more widespread use\\u000a of artificial reproductive techniques has contributed to an increasing incidence of multifetal gestations. When compared to\\u000a dichorionic twins, monochorionic twins are at an increased risk for congenital anomalies as well as unique conditions including\\u000a twin–twin transfusion syndrome (TTTS), selective intrauterine

Kenneth J. Moise Jr; Ramesh Papanna

110

Pregnant and parenting adolescents and their younger sisters: the influence of relationship qualities for younger sister outcomes.  

PubMed

On the basis of social modeling theory and a sibling interaction hypothesis, it was hypothesized that specific relationship qualities between a pregnant or parenting teen and her younger sister would be associated with permissive younger sister outcomes, such as permissive childbearing attitudes and permissive sexual behavior. Results indicated that negative relationship qualities, such as rivalry, competition, and conflict, were more closely related to younger sisters engaging in problem delinquent-like behavior and sexual behavior than were positive relationship qualities, such as warmth and closeness. Additionally, a shared friendship network with the older sister was found to be associated with extensive younger sister problem behavior and sexual behavior. Three potential explanatory processes are discussed. PMID:9113588

East, P L; Shi, C R

1997-04-01

111

University of Minnesota Twin Cities  

E-print Network

University of Minnesota Twin Cities Emergency Operations Plan © 2011 Regents of the University of Minnesota. All rights reserved. Revision 5.0, September 2011 #12;University of Minnesota - Twin Cities - Twin Cities Emergency Operations Plan Revision 5.0 TABLE OF CONTENTS Basic Plan Introduction Purpose

Amin, S. Massoud

112

Do assisted-reproduction twin pregnancies require additional antenatal care?  

PubMed

Iatrogenic twinning has become the main side-effect assisted reproduction treatment. We have evaluated the evidence for additional care that assisted-reproduction twins may require compared with spontaneous twins. Misacarriages are increased in women with tubal problems and after specific treatments. Assisted-reproduction twin pregnancies complicated by a vanishing twin after 8 weeks have an increased risk of preterm delivery and of low and very low birthweight compared with singleton assisted-reproduction pregnancies. Monozygotic twin pregnancies occur at a higher rate after assisted reproduction treatment and are associated with a higher risk of perinatal complications. The incidence of placenta praevia and vasa praevia is increased in assisted-reproduction twin pregnancies. Large cohort studies do not indicate a higher rate of fetal congenital malformations in assisted-reproduction twins. Overall, assisted-reproduction twins in healthy women <45 years of age are not associated with a notable increase in antenatal complication rates and thus do not require additional antenatal care compared with spontaneous twins. The risks of maternal and fetal morbidity and mortality associated with assisted-reproduction twins is only increased in women with a pre-existing medical condition such as hypertensive disorders and diabetes and most of these risks can be avoided with single-embryo transfer. Following the birth of the first IVF baby, rumours started to spread in both the medical literature and the media about the long-term health effects for children born following assisted reproduction treatment. However, after more than 30 years, the most common complications associated with IVF treatment remain indirect and technical such as the failure of treatment and ovarian hyperstimulation. Iatrogenic twinning has become the main side-effect of assisted reproduction treatment and the increasing number of twin pregnancies, in particular in older women, has generated numerous debates on the need for additional healthcare provision. In this review, we have evaluated the evidence for additional care that assisted-conception twin pregnancies may require compared with spontaneous twin pregnancies. Twin pregnancies are obviously at higher risk of perinatal complications than singletons due to a natural increase in the incidence of fetal anomalies, antenatal disorders and obstetric and neonatal complications associated with the development of two fetuses instead of one. Overall, our review indicates that some antenatal complications are more frequent in assisted-conception twin pregnancies than in spontaneous twin pregnancies but their prevalence is low and thus their impact on the morbidity and mortality of an individual assisted-conception twin pregnancy is limited. Assisted reproduction treatment has become available to older women with pre-existing maternal medical conditions such as chronic hypertension and diabetes. The increased obstetrical risks in this population must be considered prior to attempts at assisted conception, and the transfer of more than one embryo should be avoided in women with a pre-existing maternal medical condition. PMID:23273753

Jauniaux, E; Ben-Ami, I; Maymon, R

2013-02-01

113

Pulmonary Artery Calcification in Recipient Twins of Twin to Twin Transfusion Syndrome: A Report of Three Cases  

Microsoft Academic Search

  Twin to twin transfusion syndrome may rarely complicate monochorionic twin gestation, resulting in discordant size of the\\u000a twins. Cardiac dysfunction and various types of cardiac defects have been described in the recipient twin of this syndrome.\\u000a Pulmonary artery calcification has been described earlier in one case only. We report three recipients of twin to twin transfusion\\u000a syndrome with pulmonary artery

A. Saxena; N. R. Soni

2003-01-01

114

Healthy pets, healthy people.  

PubMed

Zoonoses, diseases that can be transmitted from animals to humans, can pose serious health risks to immunocompromised people. Although pets can carry zoonoses, owning and caring for animals can benefit human health. Information exists about preventing transmission of zoonoses, but not all physicians and veterinarians provide adequate and accurate information to immunocompromised pet owners. This disease prevention/health promotion project provides physicians and veterinarians with information, created specifically to share with patients and clients, about the health risks and benefits of pet ownership. Further, "Healthy Pets, Healthy People" encourages communication between veterinarians, physicians, clients, and patients and can serve as a model program for a nation-wide effort to aid health professionals in making recommendations about pet ownership for immunocompromised people. PMID:10434969

Wong, S K; Feinstein, L H; Heidmann, P

1999-08-01

115

Identical twin discordance for the Brachmann-de Lange syndrome revisited  

SciTech Connect

The only known twin pair evidently discordantly affected for the BDLS (Brachmann-de Lange syndrome) and who had been considered monozygotic (MZ) based on blood analysis remained a problem because biological zygosity determination needed further typing. In this report we review the clinical findings of this pair of twins at the age of 20. The use of DNA fingerprinting with three multilocus probes, F10, DNT24, and 33.6, allowed us to present evidence of monozygosity with a high degree of certainty. The significance of this confirmation of discordance in determining the cause of BDLS is discussed. Intensive comparative genomic studies of the discordant twin sisters may be useful to unravel the molecular genetics of this enigmatic pattern of malformation. 21 refs., 2 figs.

Carakushansky, G.; Goncalves, M.R.; Kahn, E. [Universidade Federal do Rio de Janeiro (Brazil)] [and others] [Universidade Federal do Rio de Janeiro (Brazil); and others

1996-06-14

116

Creating Sister Cities: An Exchange Across Hemispheres  

NASA Astrophysics Data System (ADS)

Sponsored by Associated Universities, Inc. (AUI) and the National Radio Astronomy Observatory (NRAO), this project creates a cultural and educational exchange program between communities in South and North America, linking San Pedro de Atacama in Chile and Magdalena, New Mexico in the United States. Both communities have similar demographics, are in relatively undeveloped regions of high-elevation desert, and are located near major international radio astronomy research facilities. The Atacama Large Millimeter/submillimeter Array (ALMA) is just 40 km east of San Pedro; the Very Large Array (VLA) is just 40 km west of Magdalena. In February 2007, the Mayor of San Pedro and two teachers visited Magdalena for two weeks; in July 2007 three teachers from Magdalena will visit San Pedro. These visits enable the communities to lay the foundation for a permanent, unique partnership. The teachers are sharing expertise and teaching methodologies for physics and astronomy. In addition to creating science education opportunities, this project offers students linguistic and cultural connections. The town of San Pedro, Chile, hosts nearly 100,000 tourists per year, and English language skills are highly valued by local students. Through exchanges enabled by email and distance conferencing, San Pedro and Magdalena students will improve English and Spanish language skills while teaching each other about science and their respective cultures. This poster describes the AUI/NRAO Sister Cities program, including the challenges of cross-cultural communication and the rewards of interpersonal exchanges between continents and cultures.

Adams, M. T.; Cabezon, S. A.; Hardy, E.; Harrison, R. J.

2008-06-01

117

UNDERSIDE FROM SOUTH BANKS; NOTICE NEW GLUE LAM CROSSBEAMS SISTERED ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

UNDERSIDE FROM SOUTH BANKS; NOTICE NEW GLUE LAM CROSSBEAMS SISTERED TO OLDER BEAMS, NEW STRINGERS AND COMPONENTS MAKE UP A NEARLY NEW SUPPORT SYSTEM - Short Bridge, Spanning South Santiam River at High Deck Road, Cascadia, Linn County, OR

118

STATISTICAL ANALYSIS OF 'NEANTHES ARENACEODENTATA', SISTER CHROMATID EXCHANGE DATA  

EPA Science Inventory

This paper presents a statistical evaluation of the sister chromatid exchange (SCE) assay using Neanthes arenaceodentata. Specific issues discussed are distribution of baseline SCE frequencies, transformations of SCE data, statistical sensitivity of the assay, repeatability of te...

119

Degradation of Drosophila PIM regulates sister chromatid separation during mitosis  

PubMed Central

Drosophila Pimples (PIM) and Three rows (THR) are required for sister chromatid separation in mitosis. PIM accumulates during interphase and is degraded rapidly during mitosis. This degradation is dependent on a destruction box similar to that of B-type cyclins. Nondegradable PIM with a mutant destruction box can rescue sister chromatid separation in pim mutants but only when expressed at low levels. Higher levels of nondegradable PIM, as well as overexpression of wild-type PIM, inhibit sister chromatid separation. Moreover, cells arrested in mitosis before sister chromatid separation (by colcemid or by mutations in fizzy/CDC20) fail to degrade PIM. Thus, although not related by primary sequence, PIM has intriguing functional similarities to the securin proteins of budding yeast, fission yeast, and vertebrates. Whereas these securins are known to form a complex with separins, we show that PIM associates in vivo with THR, which does not contain the conserved separin domain. PMID:10970883

Leismann, Oliver; Herzig, Alf; Heidmann, Stefan; Lehner, Christian F.

2000-01-01

120

RELIGIOUS ACTIVITIES AND HEALTH OUTCOMES: THE COLLEGE BOUND SISTERS PROGRAM  

Microsoft Academic Search

http:\\/\\/www.informaworld.com\\/smpp\\/ftinterface~content=a737728563~fulltext=713240928 ***Note: Figures may be missing from this format of the document ***Note: Footnotes and endnotes indicated with parentheses Abstract: College Bound Sisters (CBS) is a program that helps younger sisters of teenage mothers change their life trajectory by accomplishing three objectives: avoidance of pregnancy, completion of high school, and enrollment in college. Data related to religious activities and accomplishment

Lauren W. Smith; Hazel N. Brown; Lynne P. Lewallen; Judith M. Penny

2006-01-01

121

Twinning-like lattice reorientation without a crystallographic twinning plane  

NASA Astrophysics Data System (ADS)

Twinning on the plane is a common mode of plastic deformation for hexagonal-close-packed metals. Here we report, by monitoring the deformation of submicron-sized single-crystal magnesium compressed normal to its prismatic plane with transmission electron microscopy, the reorientation of the parent lattice to a ‘twin’ lattice, producing an orientational relationship akin to that of the conventional twinning, but without a crystallographic mirror plane, and giving plastic strain that is not simple shear. Aberration-corrected transmission electron microscopy observations reveal that the boundary between the parent lattice and the ‘twin’ lattice is composed predominantly of semicoherent basal/prismatic interfaces instead of the twinning plane. The migration of this boundary is dominated by the movement of these interfaces undergoing basal/prismatic transformation via local rearrangements of atoms. This newly discovered deformation mode by boundary motion mimics conventional deformation twinning but is distinct from the latter and, as such, broadens the known mechanisms of plasticity.

Liu, Bo-Yu; Wang, Jian; Li, Bin; Lu, Lu; Zhang, Xi-Yan; Shan, Zhi-Wei; Li, Ju; Jia, Chun-Lin; Sun, Jun; Ma, Evan

2014-02-01

122

Twinning-like lattice reorientation without a crystallographic twinning plane  

PubMed Central

Twinning on the plane is a common mode of plastic deformation for hexagonal-close-packed metals. Here we report, by monitoring the deformation of submicron-sized single-crystal magnesium compressed normal to its prismatic plane with transmission electron microscopy, the reorientation of the parent lattice to a ‘twin’ lattice, producing an orientational relationship akin to that of the conventional twinning, but without a crystallographic mirror plane, and giving plastic strain that is not simple shear. Aberration-corrected transmission electron microscopy observations reveal that the boundary between the parent lattice and the ‘twin’ lattice is composed predominantly of semicoherent basal/prismatic interfaces instead of the twinning plane. The migration of this boundary is dominated by the movement of these interfaces undergoing basal/prismatic transformation via local rearrangements of atoms. This newly discovered deformation mode by boundary motion mimics conventional deformation twinning but is distinct from the latter and, as such, broadens the known mechanisms of plasticity. PMID:24522756

Liu, Bo-Yu; Wang, Jian; Li, Bin; Lu, Lu; Zhang, Xi-Yan; Shan, Zhi-Wei; Li, Ju; Jia, Chun-Lin; Sun, Jun; Ma, Evan

2014-01-01

123

Concurrent evolution of ancient sister lakes and sister species: the freshwater gastropod genus Radix in lakes Ohrid and Prespa  

Microsoft Academic Search

Ancient sister lakes are considered to be ancient lakes lying in close geographic proximity, sharing a related origin and\\u000a significant time of coexistence, usually having hydrological connection as well as a balanced degree of faunal overlap and\\u000a distinctness. A paradigm for studying sister lake relationships are the ancient lakes Ohrid and Prespa in the Balkans, which\\u000a are characterized by high

Christian Albrecht; Christian Wolff; Peter Glöer; Thomas Wilke

124

Concurrent evolution of ancient sister lakes and sister species: the freshwater gastropod genus Radix in lakes Ohrid and Prespa  

Microsoft Academic Search

Ancient sister lakes are considered to be ancient lakes lying in close geographic proximity, sharing a related origin and\\u000a significant time of co-existence, usually having hydrological connection as well as a balanced degree of faunal overlap and\\u000a distinctness. A paradigm for studying sister lake relationships are the ancient lakes Ohrid and Prespa in the Balkans, which\\u000a are characterized by high

Christian Albrecht; Christian Wolff; Peter Glöer; Thomas Wilke

2008-01-01

125

Tribute to dr louis keith: twin and physician extraordinaire/twin research reports: influences on asthma severity; chimerism revisited; DNA strand break repair/media reports: twins born apart; elevated twin frequencies; celebrity father of twins; conjoined twinning.  

PubMed

The International Society for Twin Studies has lost a valued friend and colleague. Dr Louis Keith, Emeritus Professor of Obstetrics and Gynecology at Northwestern University, in Chicago, passed away on Sunday, July 6, 2014. His life and work with twins will be acknowledged at the November 2014 International Twin Congress in Budapest, Hungary. Next, twin research reports on the severity of asthma symptoms, a case of chimerism, and factors affecting DNA breakage and repair mechanisms are reviewed. Media reports cover twins born apart, elevated twin frequencies, a celebrity father of twins, and a family's decision to keep conjoined twins together. PMID:25213730

Segal, Nancy L

2014-10-01

126

A Computational Discriminability Analysis on Twin Fingerprints  

NASA Astrophysics Data System (ADS)

Sharing similar genetic traits makes the investigation of twins an important study in forensics and biometrics. Fingerprints are one of the most commonly found types of forensic evidence. The similarity between twins’ prints is critical establish to the reliability of fingerprint identification. We present a quantitative analysis of the discriminability of twin fingerprints on a new data set (227 pairs of identical twins and fraternal twins) recently collected from a twin population using both level 1 and level 2 features. Although the patterns of minutiae among twins are more similar than in the general population, the similarity of fingerprints of twins is significantly different from that between genuine prints of the same finger. Twins fingerprints are discriminable with a 1.5%~1.7% higher EER than non-twins. And identical twins can be distinguished by examine fingerprint with a slightly higher error rate than fraternal twins.

Liu, Yu; Srihari, Sargur N.

127

Healthy Snacks  

NSDL National Science Digital Library

This animated video segment adapted from the Centers for Disease Control and Prevention, featuring American Indian characters, offers suggestions of what to eat for healthy snacks and looks at why less healthy snacks should be considered sometimes foods.

Foundation, Wgbh E.

2011-07-01

128

Healthy Aging  

MedlinePLUS

Healthy Aging This category offers tips on how to stay healthy, get good health care, and manage lifestyle changes ... Problems with Smell Problems with Taste Sleep and Aging Taking Medicines Talking with Your Doctor These Age ...

129

Healthy Eating  

NSDL National Science Digital Library

Using websites and interactive games students will discover how eating healthy effects their bodies. Healthy eating is important in helping our bodies function at their best! Follow the links below and then answer the questions in our Healthy Foods project folder on our class wiki! VisitDining Decisionsand play a fun game where you will load your lunch tray with healthy choices. How do your current lunch choices ...

Smith, Mrs.

2011-12-12

130

Ex utero intrapartum treatment procedure for management of congenital high airway obstruction syndrome in a vertex/breech twin gestation.  

PubMed

Congenital high airway obstruction syndrome (CHAOS) is one indication for the ex utero intrapartum treatment (EXIT), which is used to secure the fetal airway, while fetal oxygenation is maintained by uteroplacental circulation. We report a successful EXIT procedure in a twin gestation in which one child had CHAOS while the other was a healthy child without any congenital abnormalities. After version of Twin B to allow for delivery of Twin A, Twin B underwent airway evaluation and tracheostomy for laryngeal atresia prior to delivery. PMID:23260572

Elliott, Richard; Vallera, Cristianna; Heitmiller, Eugenie S; Isaac, Gillian; Lee, Michael; Crino, Jude; Boss, Emily F; Ishman, Stacey L

2013-03-01

131

Ischemic Ileal Perforation in the Donor of Monochorionic Twins Complicated by Twin-Twin Transfusion Syndrome  

Microsoft Academic Search

Twin-twin transfusion syndrome (TTTS) carries a significant risk of perinatal morbidity and mortality. Serial amnioreduction and fetoscopic laser photocoagulation have decreased perinatal mortality, thereby shifting attention towards short-term and long-term morbidity. Most morbidity occurs within the central nervous system. Ischemic lesions, however, such as congenital skin loss and limb necrosis may occur anywhere in the vasculature of recipient twins. Ischemia

Kiyomi Tsukimori; Yasuo Yumoto; Kouji Masumoto; Tomoaki Taguchi; Haruhiko Kondo; Katsuo Sueishi; Norio Wake

2009-01-01

132

Healthy Eating  

MedlinePLUS

Healthy Eating Alzheimer’s Caregiving Tips Eating healthy foods helps everyone stay well. It’s even more important for people with Alzheimer’s disease. Here are some tips for healthy eating. Buying and Preparing Food When the person with ...

133

Volcano hazards in the Three Sisters region, Oregon  

USGS Publications Warehouse

Three Sisters is one of three potentially active volcanic centers that lie close to rapidly growing communities and resort areas in Central Oregon. Two types of volcanoes exist in the Three Sisters region and each poses distinct hazards to people and property. South Sister, Middle Sister, and Broken Top, major composite volcanoes clustered near the center of the region, have erupted repeatedly over tens of thousands of years and may erupt explosively in the future. In contrast, mafic volcanoes, which range from small cinder cones to large shield volcanoes like North Sister and Belknap Crater, are typically short-lived (weeks to centuries) and erupt less explosively than do composite volcanoes. Hundreds of mafic volcanoes scattered through the Three Sisters region are part of a much longer zone along the High Cascades of Oregon in which birth of new mafic volcanoes is possible. This report describes the types of hazardous events that can occur in the Three Sisters region and the accompanying volcano-hazard-zonation map outlines areas that could be at risk from such events. Hazardous events include landslides from the steep flanks of large volcanoes and floods, which need not be triggered by eruptions, as well as eruption-triggered events such as fallout of tephra (volcanic ash) and lava flows. A proximal hazard zone roughly 20 kilometers (12 miles) in diameter surrounding the Three Sisters and Broken Top could be affected within minutes of the onset of an eruption or large landslide. Distal hazard zones that follow river valleys downstream from the Three Sisters and Broken Top could be inundated by lahars (rapid flows of water-laden rock and mud) generated either by melting of snow and ice during eruptions or by large landslides. Slow-moving lava flows could issue from new mafic volcanoes almost anywhere within the region. Fallout of tephra from eruption clouds can affect areas hundreds of kilometers (miles) downwind, so eruptions at volcanoes elsewhere in the Cascade Range also contribute to volcano hazards in Central Oregon. This report is intended to aid scientists, government officials, and citizens as they work together to reduce the risk from volcano hazards through public education and emergency-response planning.

Scott, William E.; Iverson, R. M.; Schilling, S. P.; Fisher, B. J.

2001-01-01

134

Neonatal morbidity in twin-twin transfusion syndrome.  

PubMed

Twin-twin transfusion syndrome (TTTS) is a severe complication of monochorionic twin pregnancies associated with high perinatal mortality and morbidity rates. Management in TTTS is a major challenge for obstetricians and neonatologists. Twins which are often born prematurely and may suffer from typical conditions associated with prematurity. In addition, surviving twins with TTTS are at increased risk for other complications including neurological, cardiovascular, renal and hematologic morbidity. Rare complications such as hypoxic-ischemic lesions to limbs or intestines and amniotic band syndrome have also been reported in TTTS survivors. This review focuses on the neonatal and pediatric mortality and morbidity in TTTS survivors, with special emphasis on the long-term neurodevelopmental outcome. PMID:21784588

Lopriore, Enrico; Oepkes, Dick; Walther, Frans J

2011-09-01

135

Genetic control of adrenergic receptors on human platelets. A twin study  

Microsoft Academic Search

It was examined whether genetic factors are involved in the expression of alpha-2 adrenergic receptors on human platelets, as measured with 3H-yohimbine as ligand. The twin series comprised 17 monozygotic and 15 dizygotic adult, healthy, male, drug-free twin pairs. For control of intraindividual and interassay variation, 13 unrelated pairs of subjects were examined. Bmax values for 3H-yohimbine binding (range 91–305

P. Propping; Waltraut Friedl

1983-01-01

136

Occurrence of Different External Ear Deformities in Monozygotic Twins: Report of 2 Cases  

PubMed Central

Summary: Microtia is a spectrum of congenital deformities, which varies from barely discernable to anotia. Twinning is a well-known risk factor for congenital defects including external ear deformities. Monozygotic twins usually show identical appearances as well as congenital malformations. In special conditions as ear deformities, “mirror-image” may also occur. We report 2 cases of monozygotic twins with different ear deformities. The 8-year-old propositus with lobule type microtia and her identical female twin presented with facial symmetry. Patient A had sausage-type right microtia with absence of external auditory canal. The left external ear showed normal appearance. Patient B presented with left-sided preauricular skin tag and right-sided malformation of tragus with skin tag combined with hyperplasia of underlying cartilage. A granule-size skin tag was also noticed at crus of right helix. A 7-year-old male patient with right-sided conchal type microtia presented to an ear reconstruction center. The patient’s mother showed normal auricular appearance. Her monozygotic twin sister, whose son and daughter had normal ear appearance, was diagnosed with a leftsided lobule type microtia. PMID:25426389

Hu, Jin-Tian; Liu, Tun; Qian, Jin; Zhang, Yong-Biao; Zhou, Xu

2014-01-01

137

Size effects in twinned nanopillars  

NASA Astrophysics Data System (ADS)

Nanotwinned structures are becoming increasingly attractive owing to their potential as optimal motifs for strength, ductility, and grain stability in metals. In this work, we use nanopillar compression as a paradigmatic problem to investigate the interplay between size effects associated with the twin spacing and the finite size of the nanopillars by way of molecular dynamics simulations. Our simulations reveal that the aspect ratio plays an important role in governing the weakening or strengthening effect of coherent twin boundaries under uniaxial compression. We find that there exists an optimal aspect ratio for which the yield strength of twinned nanopillars is slightly higher than even single crystal nanopillars. In addition, we observe that twin boundaries facilitate dislocation-starvation as defects glide along twin boundaries and are eliminated at the free surface.

Hammami, Farah; Kulkarni, Yashashree

2014-07-01

138

Preparing for Twins  

MedlinePLUS

... landing page Articles News Books Understanding UV and Pollen Indexes (Audio) Sports Injuries Treatment Expect Respect: Healthy Relationships Is Your Child Ready for Sports? Toddler Speech Development (Audio) Incidence of Non-Fatal Pediatric Firearm Injuries ...

139

Uneven X inactivation in a female monozygotic twin pair with Fabry disease and discordant expression of a novel mutation in the alpha-galactosidase A gene.  

PubMed Central

We describe two female monozygotic (MZ) twins heterozygous for Fabry disease, an X linked disorder resulting from the deficient activity of alpha-galactosidase A. While one of the twins was clinically affected, the other was asymptomatic. Enzymatic assay of alpha-galactosidase in blood leucocytes, skin fibroblasts, Epstein-Barr virus transformed lymphoid cell lines, and hair follicles of the twins and their parents confirmed the heterozygous status of the twins and indicated that Fabry disease had occurred as a result of a de novo mutation. The son of the unaffected twin sister was shown to be hemizygous. Molecular analysis of the alpha-galactosidase A gene permitted the identification of an as yet undescribed point mutation at position 10182 of exon 5 which causes an Asp to Asn substitution at codon 231. Single strand conformation polymorphism (SSCP) analysis again showed the heterozygous status of the twins and a normal pattern in their parents. The basis for the discordant expression of this d novo mutation in the twins was investigated by studying their X inactivation status. Analysis of the inactive X specific methylation at the androgen receptor gene showed unbalanced inactivation in the twins' fibroblasts and in opposite directions. While the maternally derived X chromosome was preferentially active in the asymptomatic twin, the paternal X chromosome was active in the other, affected twin and was found in her hemizygotic nephew. These data suggest that the paternal X chromosome carries the de novo alpha-galactosidase A mutation and that uneven X inactivation is the underlying mechanism for disease expression in this novel female MZ twin pair. This is the first documented case of female twins discordant for Fabry disease. Images PMID:8863162

Redonnet-Vernhet, I; Ploos van Amstel, J K; Jansen, R P; Wevers, R A; Salvayre, R; Levade, T

1996-01-01

140

Catholic sister nurses in Selma, Alabama, 1940-1972.  

PubMed

This study analyzes the activities of religious sister nurses as they confronted racism in the American South from 1940 to 1972. Selma was chosen as a case study because, in the 1960s, events in that southern town marked a turning point in the civil rights movement in the United States. This is a story about the workings of gender, race, religion, and nursing. The sisters' work demonstrates how an analysis of race in nursing history is incomplete without an understanding of the roles that a number of Catholic religious women took in reaching out to African Americans in the Deep South. PMID:19218843

Wall, Barbra Mann

2009-01-01

141

Geologic map of Three Sisters volcanic cluster, Cascade Range, Oregon  

USGS Publications Warehouse

The cluster of glaciated stratovolcanoes called the Three Sisters—South Sister, Middle Sister, and North Sister—forms a spectacular 20-km-long reach along the crest of the Cascade Range in Oregon. The three eponymous stratocones, though contiguous and conventionally lumped sororally, could hardly display less family resemblance. North Sister (10,085 ft), a monotonously mafic edifice at least as old as 120 ka, is a glacially ravaged stratocone that consists of hundreds of thin rubbly lava flows and intercalated falls that dip radially and steeply; remnants of two thick lava flows cap its summit. Middle Sister (10,047 ft), an andesite-basalt-dacite cone built between 48 and 14 ka, is capped by a thick stack of radially dipping, dark-gray, thin mafic lava flows; asymmetrically glaciated, its nearly intact west flank contrasts sharply with its steep east face. Snow and ice-filled South Sister is a bimodal rhyolitic-intermediate edifice that was constructed between 50 ka and 2 ka; its crater (rim at 10,358 ft) was created between 30 and 22 ka, during the most recent of several explosive summit eruptions; the thin oxidized agglutinate that mantles its current crater rim protects a 150-m-thick pyroclastic sequence that helped fill a much larger crater. For each of the three, the eruptive volume is likely to have been in the range of 15 to 25 km³, but such estimates are fairly uncertain, owing to glacial erosion. The map area consists exclusively of Quaternary volcanic rocks and derivative surficial deposits. Although most of the area has been modified by glaciation, the volcanoes are young enough that the landforms remain largely constructional. Furthermore, twelve of the 145 eruptive units on the map are postglacial, younger than the deglaciation that was underway by about 17 ka. The most recent eruptions were of rhyolite near South Sister, about 2,000 years ago, and of mafic magma near McKenzie Pass, about 1,500 years ago. As observed by trailblazing volcanologist, Howel Williams, "For magnificence of glacial scenery, for wealth of recent lavas, and for graphic examples of dissected volcanoes, no part of this range surpasses the area embracing the Sisters and McKenzie Pass." Scientific and journalistic interest in the Three Sisters volcanic cluster was aroused a few years ago when ongoing uplift centered about 5 km west of South Sister was identified, first recognized by satellite imagery in 2001. Subsequent geodetic measurements and continuing satellite imagery analysis confirmed 3 to 4 cm/yr uplift during the interval from 1997 to 2004; the uplift has been modelled as inflation thought to be caused by an intracrustal intrusion, largely aseismic and plausibly involving mafic magma.

Hildreth, Wes; Fierstein, Judy; Calvert, Andrew T.

2012-01-01

142

Eating Healthy  

NSDL National Science Digital Library

Learn about different healthy diets and exercises that can help your body achieve mental and physical wellness. It's time to learn about what we can do to help us stay healthy and fit! Explore these following websites in order to learn more about healthy diets, good nutrition, and great exercises: Dining Decisions Nutrients Your Body Needs Pyramid Blast Off Now that you've finished exploring these resources, answer the following questions: 1. Think about you're average daily ...

Kellersberger, Ms.

2011-12-12

143

Healthy Eating  

NSDL National Science Digital Library

Learn about different healthy diets and exercises that can help your body achieve mental and physical wellness. It's time to learn about what we can do to help us stay healthy and fit! Explore these following websites in order to learn more about healthy diets, good nutrition, and great exercises: Dining Decisions Nutrients Your Body Needs Pyramid Blast Off Now that you've finished exploring these resources, answer the following questions: 1. Think about you're average daily ...

Adle, Sara

2011-08-05

144

Best Practices for Twin Placement in School  

ERIC Educational Resources Information Center

The children's book "Two Is for Twins" celebrates twins and illustrates the many "twos" in a child's world. The uniqueness of twos does not have to mean separate classrooms for twins in child development programs, preschool, or elementary school settings. With recent dramatic increases in the US twin population, how should educators address the…

Lacina, Jan

2012-01-01

145

Distinguishing identical twins by face recognition  

Microsoft Academic Search

The paper measures the ability of face recognition algorithms to distinguish between identical twin siblings. The experimental dataset consists of images taken of 126 pairs of identical twins (252 people) collected on the same day and 24 pairs of identical twins (48 people) with images collected one year apart. In terms of both the number of paris of twins and

P. Jonathon Phillips; Patrick J. Flynn; Kevin W. Bowyer; Richard W. Vorder Bruegge; Patrick J. Grother; George W. Quinn; Matthew Pruitt

2011-01-01

146

The Genetic Relationship between Indentical Twins.  

ERIC Educational Resources Information Center

Reviews current research on a woman's chances of bearing twins and the genetic relationship, prenatal competition, and personality similarities between twins. In addition, the nature/nurture controversy is discussed in terms of evidence from studies of identical twins reared apart. Future studies are suggested to discover the ways twinning might…

Herman, Rosemary

1984-01-01

147

Mechanism of slip and twinning  

NASA Technical Reports Server (NTRS)

The objectives are to: (1) demonstrate the mechanisms of deformation in body centered cubic (BCC), face centered cubic (FCC), and hexagonal close-packed (HCP)-structure metals and alloys and in some ceramics as well; (2) examine the deformed microstructures (slip lines and twin boundaries) in different grains of metallic and ceramic specimens; and (3) study visually the deformed macrostructure (slip and twin bands) of metals and alloys. Some of the topics covered include: deformation behavior of materials, mechanisms of plastic deformation, slip bands, twin bands, ductile failure, intergranular fracture, shear failure, slip planes, crystal deformation, and dislocations in ceramics.

Rastani, Mansur

1992-01-01

148

Precocious sister chromatid separation (PSCS) in Cornelia de Lange syndrome.  

PubMed

The Cornelia de Lange syndrome (CdLS) (OMIM# 122470) is a dominantly inherited multisystem developmental disorder. The phenotype consists of characteristic facial features, hirsutism, abnormalities of the upper extremities ranging from subtle changes in the phalanges and metacarpal bones to oligodactyly and phocomelia, gastroesophageal dysfunction, growth retardation, and neurodevelopmental delay. Prevalence is estimated to be as high as 1 in 10,000. Recently, mutations in NIPBL were identified in sporadic and familial CdLS cases. To date, mutations in this gene have been identified in over 45% of individuals with CdLS. NIPBL is the human homolog of the Drosophila Nipped-B gene. Although its function in mammalian systems has not yet been elucidated, sequence homologs of Nipped-B in yeast (Scc2 and Mis4) are required for sister chromatid cohesion during mitosis, and a similar role was recently demonstrated for Nipped-B in Drosophila. In order to evaluate NIPBL role in sister chromatid cohesion in humans, metaphase spreads on 90 probands (40 NIPBL mutation positive and 50 NIPBL mutation negative) with CdLS were evaluated for evidence of precocious sister chromatid separation (PSCS). We screened 50 metaphases from each proband and found evidence of PSCS in 41% (compared to 9% in control samples). These studies indicate that NIPBL may play a role in sister chromatid cohesion in humans as has been reported for its homologs in Drosophila and yeast. PMID:16100726

Kaur, Maninder; DeScipio, Cheryl; McCallum, Jennifer; Yaeger, Dinah; Devoto, Marcella; Jackson, Laird G; Spinner, Nancy B; Krantz, Ian D

2005-09-15

149

Precocious Sister Chromatid Separation (PSCS) in Cornelia de Lange Syndrome  

PubMed Central

The Cornelia de Lange syndrome (CdLS) (OMIM# 122470) is a dominantly inherited multisystem developmental disorder. The phenotype consists of characteristic facial features, hirsutism, abnormalities of the upper extremities ranging from subtle changes in the phalanges and metacarpal bones to oligodactyly and phocomelia, gastroesophageal dysfunction, growth retardation, and neurodevelopmental delay. Prevalence is estimated to be as high as 1 in 10,000. Recently, mutations in NIPBL were identified in sporadic and familial CdLS cases. To date, mutations in this gene have been identified in over 45% of individuals with CdLS. NIPBL is the human homolog of the Drosophila Nipped-B gene. Although its function in mammalian systems has not yet been elucidated, sequence homologs of Nipped-B in yeast (Scc2 and Mis4) are required for sister chromatid cohesion during mitosis, and a similar role was recently demonstrated for Nipped-B in Drosophila. In order to evaluate NIPBL role in sister chromatid cohesion in humans, metaphase spreads on 90 probands (40 NIPBL mutation positive and 50 NIPBL mutation negative) with CdLS were evaluated for evidence of precocious sister chromatid separation (PSCS). We screened 50 metaphases from each proband and found evidence of PSCS in 41% (compared to 9% in control samples). These studies indicate that NIPBL may play a role in sister chromatid cohesion in humans as has been reported for its homologs in Drosophila and yeast. PMID:16100726

Kaur, Maninder; DeScipio, Cheryl; McCallum, Jennifer; Yaeger, Dinah; Devoto, Marcella; Jackson, Laird G.; Spinner, Nancy B.; Krantz, Ian D.

2009-01-01

150

Hearing My Mother's Voice: A Study of Sisters and Mothers.  

ERIC Educational Resources Information Center

There seems to be an assumption among many people that parents can mold the later adult personality of their offspring by manipulating their childhood upbringing. To tease out the variables in childrearing and to discover some of the sources of the childbearing practices of mothers in the 1980s, a study of sisters and their mothers (N=48) in the…

Morris, Beverley

151

Sister Chromatid Cohesion and Aneuploidy Erwan Watrin* and Claude Prigent*  

E-print Network

molecules are held together from their synthesis during S-phase until their separation in mitosis during mitosis (for review, see Nasmyth, 2001). Indeed, in early mitosis, cohesion between sister required for the proper distribution of replicated genomes during mitosis, but is also essential

Paris-Sud XI, Université de

152

Identification of a Sister Gene to P-Glycoprotein1  

Microsoft Academic Search

The P-glycoproteins (Pgps) are a small family of transport proteins associated with the multidrug resistance phenotype of cell lines selected for growth in cytotoxic drugs. Utilizing low stringency screening, we have identified a novel gene closely related to the Pgps expressed in the pig and other mammalian liver which we have called Sister of P-glycoprotein (spgp ). Sequence of this

Sarah Childs; Richard Lin Yeh; Elias Georges; Victor Ling

153

Preparation and Staining of Mammal Cells to View Sister Chromatids  

NSDL National Science Digital Library

This activity was developed in the laboratory of Dr. Pablo Arenaz at the University of Texas at El Paso during a summer teacher research fellowship program sponsored by the American Society For Cell Biology. This protocol allows you to see chromatids in mammal tissue. The protocol below was used to observe sister chromatid exchanges in Chinese Hamster Ovary Cells (Cell line AA8).

Charles E. Geach (Technology & Information Systems REV)

1994-07-30

154

Clinical Design Sciences: A View from Sister Design Efforts.  

ERIC Educational Resources Information Center

Asserts that the social sciences are clinical-like endeavors, and the way that "sister" fields discover and validate their results may inform research practice in education. Describes three fields of design that confront similar societal demands for improvement (engineering product design, research on the diffusion of innovations, and management…

Zaritsky, Raul; Kelly, Anthony E.; Flowers, Woodie; Rogers, Everett; O'Neill, Patrick

2003-01-01

155

Chromosome condensation and sister chromatid pairing in budding yeast  

Microsoft Academic Search

We have developed a fluorescent in situ hy- bridization (FISH) method to examine the structure of both natural chromosomes and small artificial chromo- somes during the mitotic cycle of budding yeast. Our results suggest that the pairing of sister chromatids: (a) occurs near the centromere and at multiple places along the chromosome arm as has been observed in other eukaryotic

Vincent Guacci; Eileen Hogan; Douglas Koshland

1994-01-01

156

Pulmonary capillaritis in monozygotic twin boys.  

PubMed

Pulmonary hemorrhage can be classified as either proximal or distal (alveolar). Causes of proximal hemorrhage include infection, foreign body aspiration, pulmonary embolus, trauma, vascular malformation, and pulmonary hypertension. Causes of distal or diffuse alveolar hemorrhage are divided by the histologic presence or absence of capillaritis, which is characterized by inflammation of the alveolar interstitium and pulmonary capillary structure. Pulmonary capillaritis is a rare event in children and is associated with higher morbidity and mortality than diffuse alveolar hemorrhage without capillaritis. This is a report of 17-month-old previously healthy monozygotic twins presenting simultaneously with diffuse alveolar hemorrhage, pulmonary capillaritis, and an otherwise negative serologic workup. This suggests a role of genetic predisposition in this rare disease. PMID:24127476

Kupfer, Oren; Ridall, Leslie A; Hoffman, Lindsey M; Dishop, Megan K; Soep, Jennifer B; Wagener, Jeffrey S; Fan, Leland L

2013-11-01

157

20 CFR 410.340 - Determination of relationship; parent, brother, or sister.  

Code of Federal Regulations, 2010 CFR

...false Determination of relationship; parent, brother, or sister...340 Determination of relationship; parent, brother, or sister...individual does not bear the relationship to the miner of parent, brother, or...

2010-04-01

158

20 CFR 725.224 - Determination of relationship; parent, brother, or sister.  

Code of Federal Regulations, 2011 CFR

...2011-04-01 2011-04-01 false Determination of relationship; parent, brother, or sister. 725.224 Section 725...augmented Benefits) § 725.224 Determination of relationship; parent, brother, or sister. (a) An individual...

2011-04-01

159

20 CFR 725.224 - Determination of relationship; parent, brother, or sister.  

...2014-04-01 2014-04-01 false Determination of relationship; parent, brother, or sister. 725.224 Section 725...augmented Benefits) § 725.224 Determination of relationship; parent, brother, or sister. (a) An individual...

2014-04-01

160

20 CFR 725.224 - Determination of relationship; parent, brother, or sister.  

Code of Federal Regulations, 2010 CFR

...2010-04-01 2010-04-01 false Determination of relationship; parent, brother, or sister. 725.224 Section 725...augmented Benefits) § 725.224 Determination of relationship; parent, brother, or sister. (a) An individual...

2010-04-01

161

20 CFR 725.224 - Determination of relationship; parent, brother, or sister.  

Code of Federal Regulations, 2012 CFR

...2012-04-01 2012-04-01 false Determination of relationship; parent, brother, or sister. 725.224 Section 725...augmented Benefits) § 725.224 Determination of relationship; parent, brother, or sister. (a) An individual...

2012-04-01

162

20 CFR 725.224 - Determination of relationship; parent, brother, or sister.  

Code of Federal Regulations, 2013 CFR

...2013-04-01 2013-04-01 false Determination of relationship; parent, brother, or sister. 725.224 Section 725...augmented Benefits) § 725.224 Determination of relationship; parent, brother, or sister. (a) An individual...

2013-04-01

163

20 CFR 410.340 - Determination of relationship; parent, brother, or sister.  

Code of Federal Regulations, 2011 CFR

...false Determination of relationship; parent, brother, or sister...340 Determination of relationship; parent, brother, or sister...individual does not bear the relationship to the miner of parent, brother, or...

2011-04-01

164

Deformation twinning and twinning related fracture in coarse-grained ?-uranium  

NASA Astrophysics Data System (ADS)

An investigation of deformation twinning in coarse-grained ?-uranium was conducted within the heat-affected zone of weld specimens tested in tension. Twins and twin interactions were studied both at fracture surfaces and sub-surface, using transmission electron microscopy (TEM) and electron backscatter diffraction (EBSD). The fracture surface plane was identified using TEM of foils cut from the fracture surface using a focused ion beam. Intersecting twins found in these foils were also analyzed. EBSD was also used to analyze twins and twin interactions at and below the fracture surface. Fracture parallel to {1 7 2} twin planes and {1 7 2} twin crossings were observed, in agreement with previous optical/Laue diffraction studies. Previously unobserved crossings of {1 7 2} twins by {1 1 2} twins were also frequently observed. These twin interactions are interpreted in terms of previously established crystallographic criteria for twin crossings.

Field, R. D.; McCabe, R. J.; Alexander, D. J.; Teter, D. F.

2009-07-01

165

Monozygotic twins with Apert syndrome.  

PubMed

Apert syndrome results almost exclusively from one of two point mutations (Ser252Trp or Pro253Arg) in fibroblast growth factor receptor 2. Most patients with Apert syndrome have this as an autosomal dominant abnormality. The majority of cases are sporadic, resulting from new mutations. Although there have been some descriptions of familial Apert syndrome, we could find only one previous description in the English literature about twinning in Apert syndrome. This report demonstrates monozygotic twins affected by Apert syndrome with both boys having the Ser252Trp mutation. Although the general constellation of clinical findings was characteristic for Apert syndrome, this case report is unique since the twins had different craniofacial and hand features. One of our twins had a metopic synostosis while Apert syndrome is often characterized by the large metopic suture that closes much later when compared to normal children. PMID:18215098

Breugem, Corstiaan C; Fitzpatrick, Donald F; Verchere, Cynthia

2008-01-01

166

Twin photons and squeezed light  

Microsoft Academic Search

Squeezing in various nonlinear interactions can be theoretically evaluated using a new semi-classical method which is a linear input-output transformation for quantum fluctuations. We present experimental results concerning the generation of twin photon beams using a non degenerate Optical Parametric Oscillator and the generation of a high intensity sub-Poissonian light using an optoelectronic feedforward correction of one of these twin

A. Heidmann

1991-01-01

167

Observations of the Atomic Structure of Tensile and Compressive Twin Boundaries and Twin-Twin Interactions in Zirconium  

NASA Astrophysics Data System (ADS)

The boundary structures of twins in the hexagonal close-packed metal zirconium were studied. High-resolution transmission electron microscopy was used to characterize the boundary structure of {10bar{1}2} (T1), {bar{1}bar{1}21} (T2), and {bar{1}bar{1}22} (C1) twins on the atomic level. Basal-prismatic (B-P) plane faceting is observed along the T1 twin boundaries, matching previous observations of T1 twins in magnesium. C1 twins are observed to form basal-pyramidal (B-Py) facets along otherwise perfect twin planes. T2 twins exhibit faceting that aligns prism planes with second-order pyramidal planes across the boundary (P-Py facets). As a function of the crystallography, T2 twins appear less likely to accommodate large deviations from perfect twin planes by P-Py faceting alone, and may rely on small dislocation-accommodated facets to achieve arbitrary boundary planes. The structure of these boundaries, specifically the modes by which faceting is permitted, has a direct impact on boundary mobility. In addition, the boundary structure of two C1 twins during a twin-twin interaction event is observed, and is compared to previous observations of tensile twin-twin interactions in magnesium.

Morrow, Benjamin M.; McCabe, Rodney J.; Cerreta, Ellen K.; Tomé, Carlos N.

2014-08-01

168

“BUDDIES” OR “SLUTTIES”The Collective Sexual Reputation of Fraternity Little Sisters  

Microsoft Academic Search

Fraternity little sister organizations are a relatively unexplored aspect of the contemporary college campus culture. This article examines the construction of the collective sexual reputation of fraternity little sisters and how fraternity little sisters interpret and resist it in an effort to maintain their individual sexual reputations. Further analysis shows how fraternity men contribute to the collective sexual reputation and

MINDY STOMBLER

1994-01-01

169

Twin-to-twin transfusion syndrome: from placental anastomoses to long-term outcome  

Microsoft Academic Search

Twin-to-twin transfusion syndrome (TTTS) is a severe complication of monochorionic twin pregnancies associated with high perinatal mortality and morbidity rates. Placental vascular anastomoses, almost invariably present in monochorionic placentas, are the essential anatomical substrate for the development of TTTS. TTTS is thought to result from unbalanced inter-twin blood flow between the donor twin and the recipient twin through the vascular

Enrico Lopriore

2006-01-01

170

Conjoined hearts in thoracopagus twins.  

PubMed

This study aimed to identify the anatomic and pathologic structural cardiac abnormalities in conjoined twins and to focus on those that have prevented the successful separation of conjoined hearts. A retrospective review was undertaken to examine consecutive cases of thoracopagus conjoined twins with conjoined hearts evaluated at The Children's Hospital of Philadelphia from 1 January 1980 through 6 October 2008. The records included autopsy and surgical findings as well as clinical reports. The study group included nine sets of conjoined twins with a mean gestational age at birth of 33.8 ± 5.5 weeks. Three twin pairs were stillborn. Five twin pairs died afterward. One pair died of cardiopulmonary failure. The median age at death was 22 days (range, 0-345 days). Major congenital heart disease was present in 94.4% (17/18) of the hearts, and 72.2% (13/18) of the hearts had single-ventricle physiology. Total anomalous pulmonary venous return occurred in 39% (7/18) of the cases. The clinical outcome for thoracopagus twins with conjoined hearts remains poor because of inability to separate conjoined and single ventricles. Surgical nonintervention and palliative care should be strongly considered for these patients. PMID:22271385

Thomas Collins, R; Weinberg, Paul M; Gruber, Peter J; St John Sutton, Martin G

2012-02-01

171

A general method to determine twinning elements  

PubMed Central

The fundamental theory of crystal twinning has been long established, leading to a significant advance in understanding the nature of this physical phenomenon. However, there remains a substantial gap between the elaborate theory and the practical determination of twinning elements. This paper proposes a direct and simple method – valid for any crystal structure and based on the minimum shear criterion – to calculate various twinning elements from the experimentally determined twinning plane for Type I twins or the twinning direction for Type II twins. Without additional efforts, it is generally applicable to identify and predict possible twinning modes occurring in a variety of crystalline solids. Therefore, the present method is a promising tool to characterize twinning elements, especially for those materials with complex crystal structure. PMID:22477779

Zhang, Yudong; Li, Zongbin; Esling, Claude; Muller, Jacques; Zhao, Xiang; Zuo, Liang

2010-01-01

172

Healthy Eyes  

MedlinePLUS

... at NEI Education Programs Training and Jobs Healthy Vision Diabetes Diabetes Home How Much Do You Know? ... seeing your best. Read more. What are common vision problems? Some of the most common vision problems ...

173

Healthy Eating  

MedlinePLUS

... vegetables into the daily routine , aiming for the goal of at least five servings a day. Be ... Fresh Lunches 5 Reasons to Pack Your Lunch Smart Supermarket Shopping Your Secrets to Healthy Snacking Food ...

174

Healthy Eyes  

MedlinePLUS

... of this page please turn Javascript on. Healthy Eyes Maintaining Your Vision Click for more information Taking ... have a comprehensive dilated eye exam. Who Performs Eye Exams? An eye care professional is either an ...

175

Healthy Living  

MedlinePLUS

... active, you can be healthy and achieve your dreams. Here are five simple steps from Let’s Move! ... Office of the Inspector General Freedom of Information Act NIEHS Home NIEHS Kids' Pages are supported by ...

176

Healthy Aging  

MedlinePLUS

People in the U.S. are living longer than ever before. Many seniors live active and healthy lives. But there's no getting around one thing: as we age, our bodies and minds change. There are things ...

177

Sunset over Twin Peaks  

NASA Technical Reports Server (NTRS)

This image was taken by the Imager for Mars Pathfinder (IMP) about one minute after sunset on Mars on Sol 21. The prominent hills dubbed 'Twin Peaks' form a dark silhouette at the horizon, while the setting sun casts a pink glow over the darkening sky. The image was taken as part of a twilight study which indicates how the brightness of the sky fades with time after sunset. Scientists found that the sky stays bright for up to two hours after sunset, indicating that Martian dust extends very high into the atmosphere.

Mars Pathfinder is the second in NASA's Discovery program of low-cost spacecraft with highly focused science goals. The Jet Propulsion Laboratory, Pasadena, CA, developed and manages the Mars Pathfinder mission for NASA's Office of Space Science, Washington, D.C. JPL is an operating division of the California Institute of Technology (Caltech). The Imager for Mars Pathfinder (IMP) was developed by the University of Arizona Lunar and Planetary Laboratory under contract to JPL. Peter Smith is the Principal Investigator.

1997-01-01

178

Genomic sister-disorders of neurodevelopment: an evolutionary approach  

PubMed Central

Genomic sister-disorders are defined here as diseases mediated by duplications versus deletions of the same region. Such disorders can provide unique information concerning the genomic underpinnings of human neurodevelopment because effects of diametric variation in gene copy number on cognitive and behavioral phenotypes can be inferred. We describe evidence from the literature on deletions versus duplications for the regions underlying the best-known human neurogenetic sister-disorders, including Williams syndrome, Velocardiofacial syndrome, and Smith–Magenis syndrome, as well as the X-chromosomal conditions Klinefelter and Turner syndromes. These data suggest that diametric copy-number alterations can, like diametric alterations to imprinted genes, generate contrasting phenotypes associated with autistic-spectrum and psychotic-spectrum conditions. Genomically based perturbations to the development of the human social brain are thus apparently mediated to a notable degree by effects of variation in gene copy number. We also conducted the first analyses of positive selection for genes in the regions affected by these disorders. We found evidence consistent with adaptive evolution of protein-coding genes, or selective sweeps, for three of the four sets of sister-syndromes analyzed. These studies of selection facilitate identification of candidate genes for the phenotypes observed and lend a novel evolutionary dimension to the analysis of human cognitive architecture and neurogenetic disorders.

Crespi, Bernard; Summers, Kyle; Dorus, Steve

2009-01-01

179

Broad Phylogenomic Sampling and the Sister Lineage of Land Plants  

PubMed Central

The tremendous diversity of land plants all descended from a single charophyte green alga that colonized the land somewhere between 430 and 470 million years ago. Six orders of charophyte green algae, in addition to embryophytes, comprise the Streptophyta s.l. Previous studies have focused on reconstructing the phylogeny of organisms tied to this key colonization event, but wildly conflicting results have sparked a contentious debate over which lineage gave rise to land plants. The dominant view has been that ‘stoneworts,’ or Charales, are the sister lineage, but an alternative hypothesis supports the Zygnematales (often referred to as “pond scum”) as the sister lineage. In this paper, we provide a well-supported, 160-nuclear-gene phylogenomic analysis supporting the Zygnematales as the closest living relative to land plants. Our study makes two key contributions to the field: 1) the use of an unbiased method to collect a large set of orthologs from deeply diverging species and 2) the use of these data in determining the sister lineage to land plants. We anticipate this updated phylogeny not only will hugely impact lesson plans in introductory biology courses, but also will provide a solid phylogenetic tree for future green-lineage research, whether it be related to plants or green algae. PMID:22253761

Timme, Ruth E.; Bachvaroff, Tsvetan R.; Delwiche, Charles F.

2012-01-01

180

Calcific periarthritis as the only clinical manifestation of hypophosphatasia in middle-aged sisters.  

PubMed

Hypophosphatasia (HPP) is the inborn error of metabolism that features low serum alkaline phosphatase (ALP) activity caused by loss-of-function mutation(s) within the gene for the tissue nonspecific isoenzyme of ALP (TNSALP). In HPP, extracellular accumulation of inorganic pyrophosphate (PPi), a TNSALP substrate and inhibitor of mineralization, leads frequently to premature tooth loss and often to rickets or osteomalacia. In affected adults, the excess PPi sometimes also causes calcium pyrophosphate dihydrate (CPPD) deposition, PPi arthropathy, or pseudogout, or seemingly paradoxical deposition of hydroxyapatite crystals in ligaments or around joints when the condition is called calcific periarthritis (CP). We report three middle-aged sisters with CP as the only clinical manifestation of HPP. Each presented during early adult life with recurrent episodes of pain principally around the shoulders, elbows, wrists, hips, or Achilles tendon. Otherwise, they were in good health, including no history of unusual dental disease, fractures, or pseudofractures. Calcific deposits were identified in symptomatic areas principally by ultrasonographic assessment but also confirmed radiographically. All three sisters had low serum levels of total and bone-specific ALP, hyperphosphatemia, and increased serum concentrations of the TNSALP substrate pyridoxal 5'-phosphate together characteristic of HPP. Mutation analysis revealed that each carried a single unique 18-bp duplication within TNSALP (c.188_205dup18, p.Gly63_Thr68dup) as did two of their healthy sons and their mother, who was without signs of CPPD deposition or CP but had knee osteoarthritis. We find that CP can be the only complication of HPP in adults. Thus, multiple juxta-articular deposits of hydroxyapatite causing CP may be a useful sign of HPP, especially when the CP is familial. PMID:24123110

Guañabens, Núria; Mumm, Steven; Möller, Ingrid; González-Roca, Eva; Peris, Pilar; Demertzis, Jennifer L; Whyte, Michael P

2014-04-01

181

Twins and neural tube defects  

PubMed Central

The hypothesis that anencephalus stems from fetus-fetus interactions in dizygotic twin pairs is examined by comparing the epidemiological predictions of the hypothesis with available observations. The hypothesis itself was based upon the disease-discordance and sex-concordance characteristics of twin pairs affected with anencephalus, and upon the sex ratio of the disease itself. The testable predictions of the hypothesis are (a) that variations in the incidence of anencephalus should be related to variations in dizygotic twinning rates, and particularly that dizygotic twinning rates will set upper limits to the incidence of anencephalus, and (b) that the F/M ratio in anencephalic infants will be high in circumstances of high incidence, and specifically when the incidence is high in relation to the dizygotic twinning rate. Examples from international comparisons, secular changes, social class gradients, and variations according to maternal age confirm a consistent correspondence between observations and these predictions. In addition, the possibility was tested that some fetus-fetus interactions might be based upon sequential rather than simultaneous pairs of fetuses. This model predicted asymmetries of sex ratio in sibs immediately preceding propositi, with differences according to the sex of the affected child, and the predicted findings were confirmed. The fetus-fetus interaction hypothesis is therefore extended in the terms that about one third of occurrences are determined in a sequential manner. The success of the extended fetus-fetus interaction model in explaining a large number of otherwise unrelatable findings confirms its validity. PMID:4605406

Knox, E. G.

1974-01-01

182

150. Photocopy of drawing (taken from Twin Falls Canal Company ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

150. Photocopy of drawing (taken from Twin Falls Canal Company Surveyor's Book #363, Page 42, entitled, 'Diversion Tunnels', located in Twin Falls Canal Company office, Twin Falls, Idaho). PLAN OF DIVERSION TUNNELS, MILNER DAM. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

183

Diagnosis of twin-to-twin transfusion syndrome, selective fetal growth restriction, twin anaemia-polycythaemia sequence, and twin reversed arterial perfusion sequence.  

PubMed

Monochorionic twin pregnancies are well known to be at risk for a variety of severe complications, a true challenge for the maternal-fetal medicine specialist. With current standards of care, monochorionicity should be established in the first trimester. Subsequently, frequent monitoring using the appropriate diagnostic tools, and in-depth knowledge about the pathophysiology of all possible clinical presentations of monochorionic twin abnormalities, should lead to timely recognition, and appropriate management. Virtually all unique diseases found in monochorionic twins are directly related to placental angio-architecture. This, however, cannot be established reliably before birth. The clinician needs to be aware of the definitions and symptoms of twin-to twin transfusion syndrome, selective fetal growth restriction, twin anaemia-polycythaemia sequence, and twin reversed arterial perfusion sequence, to be able to recognise each disease and take the required action. In this chapter, we address current standards on correct and timely diagnoses of severe complications of monochorionic twin pregnancies. PMID:24433823

Sueters, Marieke; Oepkes, Dick

2014-02-01

184

Congenital tracheobronchial stenosis in monozygotic twins  

Microsoft Academic Search

  \\u000a \\u000a Conclusion This case report shows that tracheobronchial stenosis may present in monozygotic twins. The pattern of malformation in twins\\u000a differs from cases described previously.

K. S. Wong; R. Lien; T. Y. Lin

1998-01-01

185

Hartmann's vision. Identical twins and developmental organizations.  

PubMed

This paper looks back some sixty years to Hartmann's study of identical twins. Examined from the vantage point of our own contemporary investigation of twins, Hartmann's work reveals unusual vision and contains valuable hypotheses. PMID:7809302

Abrams, S; Neubauer, P B

1994-01-01

186

Cerebral palsy in the surviving twin associated with infant death of the co-twin  

Microsoft Academic Search

BACKGROUNDMonozygotic twins are at greater risk of dying and of serious morbidity than dizygotic twins, and both are at greater risk than singletons. This is only partly explained by the higher proportion of low birthweight infants among twins.AIMTo compare, in same sex and different sex twins, birth weight specific neonatal death rates and cerebral palsy prevalence rates in the surviving

P O D Pharoah

2001-01-01

187

Healthy Eating  

NSDL National Science Digital Library

This Project will help you to discover how you're eating, and how that affects your life. You will also use the tools provided to help make healthy eating choices. First, Calculate your Body Mass Index using the BMI Calculator. Then, after exploring the website, answer these questions: 1) What exactly is the BMI? 2) What are two limitations of the BMI Calculator? 3) What is a healthy BMI for YOU (age group height? 4) List 7 other risk factors that can contribute to heart ...

Brobison

2010-12-03

188

Enjoy Living Healthy Hearts, Healthy Homes  

E-print Network

Enjoy Living Smoke Free Healthy Hearts, Healthy Homes #12;Read other booklets in the Healthy Hearts-6356 June 2008 #12;2 Healthy Hearts, Healthy Homes #12;Enjoy Living Smoke Free 1 Did you know that cigarette, Healthy Homes series: Are You at Risk for Heart Disease? Do You Need To Lose Weight? Do You Know Your

Bandettini, Peter A.

189

Twin Reversed Arterial Perfusion Syndrome (TRAP or Acardiac Twin)-A Case Report  

PubMed Central

Twin reversed arterial perfusion (TRAP) syndrome is a rare condition (0.3:10,000 births) that occurs in monochorionic twin pregnancies, resulting in coexistence of a normal “pump” twin and an acardiac twin. The acardiac twin is dependent upon the normal twin to provide circulation by means of vascular anastomosis. Many of the bizarre defects are felt to be caused by low oxygen tension and this causes dramatic alteration in the twin fetal physiology and high prenatal mortality. The acardiac twin is a parasite, putting the pump fetus at risk of high output cardiac failure. Overall only 50% of pump twins survive. We present a case in a twenty year female, gravida two, para one, living one, full term normal pregnancy, ultrasound showed twin pregnancy. Following delivery, the first fetus survived only for one day and the second fetus showed features of TRAP syndrome. PMID:24596758

R., Kalyani; Bindra, Mandeep S.

2014-01-01

190

Twins reunited: scientific and personal perspectives/twin research studies: multiple birth effects on IQ and body size; life style, muscles, and metabolism; monochorionic dizygotic twin with blood chimerism; amniocentesis for twins/twins in the media: identical doctors; freedom fighter for twins; twin scholarships; Auguste and Jean-Felix Piccard; twins born apart.  

PubMed

A reunion of 38-year-old female monozygotic twins took place in Daegu, South Korea, on January 14, 2014. Scientific and personal perspectives on this extraordinary event are provided. A review of timely twin research follows, covering the effects of multiple births on IQ and body size, lifestyle and physical fitness associations, a rare case of a dizygotic twin with blood chimerism and definitional issues surrounding amniocentesis-related loss in multiple birth pregnancies. Interesting and informative mention of twins in the media includes twin doctors, a twin freedom fighter, the availability of college scholarships for twins, a new book about the Piccard family (two of whose members were twins), and co-twins born before and after the new year. A follow-up to a previous mention of identical twin biatheletes is also provided. PMID:24589452

Segal, Nancy L; Mulligan, Christy A

2014-04-01

191

34 CURA REPORTER Twin Cities Neighborhood Maps  

E-print Network

34 CURA REPORTER Twin Cities Neighborhood Maps C URA's Community Geographic Information Systems (CGIS) program has delivered training and mapping services to Twin Cities neighborhoods for more than in the National Neighborhood Indicators Partnership (NNIP).1 The September 2011 issue of Twin Cities Metro

Levinson, David M.

192

Uses and limitations of twin studies  

Microsoft Academic Search

Series of twin pairs selected because one (or both) is ill are prone to biassed ascertainment, and great care has to be taken to avoid this. Such bias is absent if the primary source is a twin registry established at birth. In general, series of twin pairs have no advantage over studies on sibs in assessing the size of genetic

Sarah Bundey

1991-01-01

193

Psychological adjustment to twins after infertility  

Microsoft Academic Search

The birth of twins and other multiples is physically and emotionally stressful. The increase in the use of the assisted reproductive technologies has lead to an exponential increase in the rates of twins and triplets in the US. Whereas the medical complications of twins and other multiples has been well studied, the psychological and social implications of these events has

Susan C. Klock

2004-01-01

194

A Twin Study of Adult Gambling Behavior  

Microsoft Academic Search

A twin study explored the possible genetic influences on gambling behavior. Male monozygotic (MZ) twins (n = 42) revealed significantly greater similarity on gambling frequency associated with “high-action” games than male dizygotic (DZ) twins (n = 50). The heritability estimates for involvement in these types of games among males were moderate and significant. All MZ versus DZ comparisons among males

Ken C. Winters; Timothy Rich

1998-01-01

195

Paternity identification in twins with different fathers.  

PubMed

If a female has sexual intercourse with two males at short intervals within the same ovulatory period, superfecundation may occur. This article reports two cases of paternity identification in twins. The results showed that each twin had come from a different father. Thus, great attention should be paid to such a situation when the twin paternity identification is asked for. PMID:8064269

Lu, H L; Wang, C X; Wu, F Q; Li, J J

1994-07-01

196

Growth of deformation twins in zinc crystals  

Microsoft Academic Search

The incorporation of slip dislocations at the coherent twin boundary has been analysed for the (112) [111] type twins in hexagonal close-packed zinc crystal by applying matrix algebra. The effects of the various dislocation incorporation processes on the growth and untwinning of the existing twin are discussed from the geometric and the energetic points of view. The results indicate that

Man Hyong Yoo; Chuan-Tseng Wei

1966-01-01

197

Twin method: Defense of a critical assumption  

Microsoft Academic Search

Since Galton's time, critics of the twin method have rejected the evidence of genetic differences in human behavior, because the twin method assumes that identical and fraternal pairs have equally similar environments. Twins whose genetic similarity is misperceived by themselves and others provide a critical test of the adequacy of this assumption. The relative effects of perceived and actual genetic

Sandra Scarr; Louise Carter-Saltzman

1979-01-01

198

On Teaching About Twins and Time  

ERIC Educational Resources Information Center

Discusses a four-step instructional presentation in which the twin on the earth is demonstrated older than the twin aboard a spaceship on the basis of the relativistic Doppler effect. Concludes that both twins can meet again at the same place in space at the expense of time. (CC)

Hewitt, Paul G.

1973-01-01

199

Mother-Infant Interactions: A Twin Perspective.  

ERIC Educational Resources Information Center

This study examined whether the differential maternal treatment of twins affected the twins' on-task behaviors in a teaching interaction. A total of 175 mothers and their same-sex 14-month-old twins were videotaped in their homes in triads. This was repeated for 170 of the families when the children were 24 months, and for 146 of the families when…

DiLalla, Lisabeth Fisher; Bishop, E. G.

200

Conjoined twins – the Cape Town experience  

Microsoft Academic Search

This paper records our experience in the management of 25 sets of conjoined twins seen over a 32 year period (1964?–?1996). The twins were classified into 14 complete and symmetrical sets and 11 incomplete or heteropagus. The 14 symmetrical sets included 9 thoracopagus, 2 ischiopagus, 1 craniopagus and 1 omphalopagus twins. In the incomplete heteropagus group there was 1 ischiopagus,

S. Cywes; A. J. W. Millar; H. Rode; R. A. Brown

1997-01-01

201

Conjoined twins — the Cape Town experience  

Microsoft Academic Search

This paper records our experience in the management of 25 sets of conjoined twins seen over a 32 year period (1964–1996). The twins were classified into 14 complete and symmetrical sets and 11 incomplete or heteropagus. The 14 symmetrical sets included 9 thoracopagus, 2 ischiopagus, I craniopagus and 1 omphalopagus twins. In the incomplete heteropagus group there was I ischiopagus,

S. Cywes; A. J. W. Millar; H. Rode; R. A. Brown

1997-01-01

202

Separated fraternal twins: Resemblance for cognitive abilities  

Microsoft Academic Search

Thirty-four pairs of Swedish fraternal twins separated in the first 10 years of life were administered 12 tests of cognitive abilities. The average age of the twins was 59 years. Nineteen pairs were separeted before the first year of life and 26 pairs (76%) were separated by the age of 5 years. Moderate positive twin correlations were found for all

N. L. Pedersen; G. E. McClearn; R. Plomin; L. Friberg

1985-01-01

203

A Powerful Twin Arrives  

NASA Astrophysics Data System (ADS)

First Images from FORS2 at VLT KUEYEN on Paranal The first, major astronomical instrument to be installed at the ESO Very Large Telescope (VLT) was FORS1 ( FO cal R educer and S pectrograph) in September 1998. Immediately after being attached to the Cassegrain focus of the first 8.2-m Unit Telescope, ANTU , it produced a series of spectacular images, cf. ESO PR 14/98. Many important observations have since been made with this outstanding facility. Now FORS2 , its powerful twin, has been installed at the second VLT Unit Telescope, KUEYEN . It is the fourth major instrument at the VLT after FORS1 , ISAAC and UVES.. The FORS2 Commissioning Team that is busy installing and testing this large and complex instrument reports that "First Light" was successfully achieved already on October 29, 1999, only two days after FORS2 was first mounted at the Cassegrain focus. Since then, various observation modes have been carefully tested, including normal and high-resolution imaging, echelle and multi-object spectroscopy, as well as fast photometry with millisecond time resolution. A number of fine images were obtained during this work, some of which are made available with the present Press Release. The FORS instruments ESO PR Photo 40a/99 ESO PR Photo 40a/99 [Preview - JPEG: 400 x 345 pix - 203k] [Normal - JPEG: 800 x 689 pix - 563kb] [Full-Res - JPEG: 1280 x 1103 pix - 666kb] Caption to PR Photo 40a/99: This digital photo shows the twin instruments, FORS2 at KUEYEN (in the foreground) and FORS1 at ANTU, seen in the background through the open ventilation doors in the two telescope enclosures. Although they look alike, the two instruments have specific functions, as described in the text. FORS1 and FORS2 are the products of one of the most thorough and advanced technological studies ever made of a ground-based astronomical instrument. They have been specifically designed to investigate the faintest and most remote objects in the universe. They are "multi-mode instruments" that may be used in several different observation modes. FORS2 is largely identical to FORS1 , but there are a number of important differences. For example, it contains a Mask Exchange Unit (MXU) for laser-cut star-plates [1] that may be inserted at the focus, allowing a large number of spectra of different objects, in practice up to about 70, to be taken simultaneously. Highly sophisticated software assigns slits to individual objects in an optimal way, ensuring a great degree of observing efficiency. Instead of the polarimetry optics found in FORS1 , FORS2 has new grisms that allow the use of higher spectral resolutions. The FORS project was carried out under ESO contract by a consortium of three German astronomical institutes, the Heidelberg State Observatory and the University Observatories of Göttingen and Munich. The participating institutes have invested a total of about 180 man-years of work in this unique programme. The photos below demonstrate some of the impressive possibilities with this new instrument. They are based on observations with the FORS2 standard resolution collimator (field size 6.8 x 6.8 armin = 2048 x 2048 pixels; 1 pixel = 0.20 arcsec). In addition, observations of the Crab pulsar demonstrate a new observing mode, high-speed photometry. Protostar HH-34 in Orion ESO PR Photo 40b/99 ESO PR Photo 40b/99 [Preview - JPEG: 400 x 444 pix - 220kb] [Normal - JPEG: 800 x 887 pix - 806kb] [Full-Res - JPEG: 2000 x 2217 pix - 3.6Mb] The Area around HH-34 in Orion ESO PR Photo 40c/99 ESO PR Photo 40c/99 [Preview - JPEG: 400 x 494 pix - 262kb] [Full-Res - JPEG: 802 x 991 pix - 760 kb] The HH-34 Superjet in Orion (centre) PR Photo 40b/99 shows a three-colour composite of the young object Herbig-Haro 34 (HH-34) , now in the protostar stage of evolution. It is based on CCD frames obtained with the FORS2 instrument in imaging mode, on November 2 and 6, 1999. This object has a remarkable, very complicated appearance that includes two opposite jets that ram into the surrounding interstellar matter. This structure is produced by a machine-gu

1999-11-01

204

NOTE: Increasing cardiac output and decreasing oxygenation sequence in pump twins of acardiac twin pregnancies  

NASA Astrophysics Data System (ADS)

An acardiac twin pregnancy is a rare but serious complication of monochorionic twinning and consists of an acardiac twin and a pump twin. The acardiac twin is a severely malformed fetus that lacks most organs, particularly a heart, but grows during pregnancy because it is perfused by the developmentally normal pump twin via a set of arterioarterial and venovenous placental anastomoses. Pump twins die intrauterine or neonatally in about 50% of the cases. Because the effects of an acardiac mass on the pump twin's development are incompletely known, methods for outcome prognosis are currently not available. We sought to derive simple relations for the pump twin's excess cardiac output and decreased oxygenation and to use available clinical cases for a preliminary test of the model. As a method, we used a theoretical flow model to represent the fetoplacental circulation of an acardiac twin pregnancy and estimated blood deoxygenation and reoxygenation following perfusion of the two bodies and placentas, respectively. The results show the pump twin's excess cardiac output and decrease of venous oxygen saturation to depend on the ratio of pump twin to acardiac twin umbilical blood flow, whose ratio can be measured by ultrasonography. The clinical cases show a decreasing umbilical flow ratio with gestation. In conclusion, prospective serial study is necessary to test whether measurement of umbilical flow ratios allows monitoring the pump twin's pathophysiologic development, possibly resulting in a guideline for prognosis of pump twin survival.

van Gemert, Martin J. C.; Umur, Asli; van den Wijngaard, Jeroen P. H. M.; Van Bavel, Ed; Vandenbussche, Frank P. H. A.; Nikkels, Peter G. J.

2005-02-01

205

Twin tower gas fractionation apparatus  

Microsoft Academic Search

An apparatus for adsorptive fractionation of a gaseous mixture. The apparatus is a twin tower fractionator or dryer including a pair of sorbent beds. A filter and valve assembly directs a flow of the gaseous mixture from a source thereof to one of the beds for removing a gaseous component of said mixture while simultaneously directing a flow of purge

R. A. Null; L. C. laughlin; M. L. Goldberg

1985-01-01

206

Twin Peaks (B/W)  

NASA Technical Reports Server (NTRS)

The Twin Peaks are modest-size hills to the southwest of the Mars Pathfinder landing site. They were discovered on the first panoramas taken by the IMP camera on the 4th of July, 1997, and subsequently identified in Viking Orbiter images taken over 20 years ago. The peaks are approximately 30-35 meters (-100 feet) tall. North Twin is approximately 860 meters (2800 feet) from the lander, and South Twin is about a kilometer away (3300 feet). The scene includes bouldery ridges and swales or 'hummocks' of flood debris that range from a few tens of meters away from the lander to the distance of the South Twin Peak. The large rock at the right edge of the scene is nicknamed 'Hippo'. This rock is about a meter (3 feet) across and 25 meters (80 feet) distant.

Mars Pathfinder is the second in NASA's Discovery program of low-cost spacecraft with highly focused science goals. The Jet Propulsion Laboratory, Pasadena, CA, developed and manages the Mars Pathfinder mission for NASA's Office of Space Science, Washington, D.C. JPL is a division of the California Institute of Technology (Caltech). The IMP was developed by the University of Arizona Lunar and Planetary Laboratory under contract to JPL. Peter Smith is the Principal Investigator.

1997-01-01

207

fMRI and corpus callosum relationships in monozygotic twins discordant for handedness.  

PubMed

To further investigate brain structure and function in 26 handedness discordant monozygotic twin pairs (MzHd), MRI and behavioural assessments were carried out. These showed significant correlation between language-specific functional laterality in inferior and middle frontal gyri, and anterior corpus callosum. Previous studies of handedness discordant monozygotic twins failed to resolve the issue concerning handedness and hemispheric laterality for language due to methodological disparities. The results would be relevant to genetic theories as well as to brain structure:function explanations. MzHd twins underwent MRI and fMRI scanning as well as behavioural assessment of motor performance and cognition. There were significant differences on MRI and fMRI laterality measures, as well as a significant correlation between anterior callosal widths and functional laterality. LH twins showed higher frequencies of atypical functional laterality. There was no significant within-twin pair correlation on fMRI verbal laterality, nor did results show within-twin pair differences on verbal fluency or IQ. Implications for the field of laterality research pertain to frontal hemispheric equipotentiality for verbal processes in healthy individuals. In particular, there can be an apparent lack of cognitive 'cost' to atypical laterality. An fMRI verbal laterality index correlated significantly with corpus callosum widths near Broca's area. PMID:22527119

Gurd, J M; Cowell, P E; Lux, S; Rezai, R; Cherkas, L; Ebers, G C

2013-03-01

208

Healthy Eating  

NSDL National Science Digital Library

Studenst will understand how a healthy diet and exercise can increase the likelihood of physical and mental wellness Read and discover what your body needs to function with the first two websites: Body Needs and Dining Decisions, Feel free to explore, discover how many servings you need of each food group and how to read nutrition labels. After you feel comfortable with the subject, go to the final ...

Ford, Ms.

2011-12-11

209

The Role of Sisters in Body Image Dissatisfaction and Disordered Eating  

Microsoft Academic Search

The Tripartite Influence Model (TIM) argues sociocultural agents affect body image dissatisfaction (BID) via the mediators\\u000a of social comparison and internalization. BID subsequently influences disordered eating. Forty-seven Australian sister pairs\\u000a (18–25 years) provided self-reports of perceived familial modeling and pressure by the sociocultural agents of mother, father\\u000a and sister, social comparison, internalization, BID, bulimic behaviors, and dietary restriction. Sisters were correlated

Kerri Coomber; Ross M. King

2008-01-01

210

Transient early preeclampsia in twin pregnancy with a triploid fetus: a case report  

PubMed Central

Introduction Triploid pregnancies have an increased risk of early preeclampsia. Twin pregnancies consisting of one healthy fetus and one complete or partial molar, with or without a triploid fetus, are rare and management is complex. Case presentation A 33-year-old Caucasian woman presented with a dichorionic diamniotic twin pregnancy. One fetus showed early growth restriction resulting in fetal death at 20 weeks. The placenta was enlarged with some cysts. Chorionic villus biopsy confirmed triploidy. At 21 weeks, the patient developed preeclampsia with a blood pressure of 154/98 mmHg and proteinuria (24 hour protein excretion of 2.5 g/L), for which she was hospitalized. Without pharmacological interventions, the blood pressure normalized and proteinuria disappeared. At 35 weeks, she again developed preeclampsia. A cesarean section was performed at 38 weeks and a healthy child was born. Conclusions Survival of the healthy fetus is possible in a twin pregnancy with a triploid fetus complicated by early preeclampsia. The pregnancy should not be terminated if the triploid twin has died and as long as conservative management is safe. PMID:19830177

2009-01-01

211

Narcolepsy with Cataplexy Mimicry: The Strange Case of Two Sisters  

PubMed Central

We report on two sisters, 17 and 12 years of age, with clinical features suggesting narcolepsy with cataplexy (NC): daytime sleepiness, spontaneous and emotionally triggered sudden falls to the ground, and overweight/obesity. MSLT showed borderline sleep latency, with 1 and 0 sleep onset REM periods. HLA typing disclosed the DQB1*0602 allele. Video-polygraphy of the spells ruled out NC diagnosis by demonstrating their easy elicitation by suggestion, with wake EEG, electromyo-graphic persistence of muscle tone, and stable presence of tendon reflexes (i.e., pseudo-cataplexy), together with normal cerebrospinal hypocretin-1 levels. Our cases emphasize the need of a clear depiction of cataplexy pattern at the different ages, the usefulness of examining ictal neurophysiology, and collecting all available disease markers in ambiguous cases. Citation: Pizza F; Vandi S; Poli F; Moghadam KK; Fran-ceschini C; Bellucci C; Cipolli C; Ingravallo F; Natalini G; Mignot E; Plazzi G. Narcolepsy with cataplexy mimicry: the strange case of two sisters. J Clin Sleep Med 2013;9(6):611-612. PMID:23772196

Pizza, Fabio; Vandi, Stefano; Poli, Francesca; Moghadam, Keivan Kaveh; Franceschini, Christian; Bellucci, Claudia; Cipolli, Carlo; Ingravallo, Francesca; Natalini, Giuliana; Mignot, Emmanuel; Plazzi, Giuseppe

2013-01-01

212

Sister chromosome pairing maintains heterozygosity in parthenogenetic lizards.  

PubMed

Although bisexual reproduction has proven to be highly successful, parthenogenetic all-female populations occur frequently in certain taxa, including the whiptail lizards of the genus Aspidoscelis. Allozyme analysis revealed a high degree of fixed heterozygosity in these parthenogenetic species, supporting the view that they originated from hybridization events between related sexual species. It has remained unclear how the meiotic program is altered to produce diploid eggs while maintaining heterozygosity. Here we show that meiosis commences with twice the number of chromosomes in parthenogenetic versus sexual species, a mechanism that provides the basis for generating gametes with unreduced chromosome content without fundamental deviation from the classic meiotic program. Our observation of synaptonemal complexes and chiasmata demonstrate that a typical meiotic program occurs and that heterozygosity is not maintained by bypassing recombination. Instead, fluorescent in situ hybridization probes that distinguish between homologues reveal that bivalents form between sister chromosomes, the genetically identical products of the first of two premeiotic replication cycles. Sister chromosome pairing provides a mechanism for the maintenance of heterozygosity, which is critical for offsetting the reduced fitness associated with the lack of genetic diversity in parthenogenetic species. PMID:20173738

Lutes, Aracely A; Neaves, William B; Baumann, Diana P; Wiegraebe, Winfried; Baumann, Peter

2010-03-11

213

Why atmospheres of two sister planets are so different?  

NASA Astrophysics Data System (ADS)

Earth and Venus are nick-named as sister planets because they have close by sizes, masses, compositions, solar distances. However, their rotation parameters and atmospheres are drastically different. This difference is so much that the planets should be rather named a brother and a sister. And who is who ? The wave planetology [1] in its third theorem ("Celestial bodies are granular") states that parameters of warping any celestial body inertia-gravity waves producing their structures are in inverse relation with their orbital frequencies: higher frequencies smaller waves and formed by their interference tectonic granulas. The Earth/Venus orbital periods are 1/0.62, The Earth/Venus tectonic granula sizes are as R:4/ R:6 (R-a body radius). Thus Venus is tectonically finer-grained than Earth. Earth is coarser, then it is a "brother" and Venus is a "sister". To put it more clearly show their position in a row of the inner planets. Mercury R/16 - afanitic structure, Venus R/6 - fine-grained, Earth R/4 - medium-grained, Mars R/2 - coarse- grained, asteroids R/1 - pegmatoid. Both secondary atmospheres of Earth and Venus one considers as a result of degassing planetary interiors. This degassing is more thorough at Venus as it is indicated by a high content in the massive venusian atmosphere of Ar-36 and nitrogen. Degassing is more intensive in finer structurized by warping waves body with more frequent oscillations. The Earth globe contains 4/3R3 : 4/3(R/8)3 =16.5 tectonic granulas. The Venus globe contains 4/3R3 : 4/3(R/12)3 = 55.7 tectonic granulas. Thus, Venus is 55.7 : 16.5= 3.38 times finer- grained. To the Earth granula making wavelength 10000 km correspond oscillations 0.03 khz, to the Venus granula making wavelength 6000 km - 0.07 khz. Thus , Venus is 0.07 : 0.03 =2.33 times more frequently shaked. Assuming that degassing is proportional to square of the production of granulation and oscillation one gets that Venus is (3.38 x 2.33)2 = 62.1 times more degassed than Earth. This is not far from the 90 times more massive venusian atmosphere. Provided all uncertainties in respect of loosing atmospheres in cosmos and burying gases in lithospheres one may conclude that the obtained results are promising. Assuming that degassing is proportional to cube of the above production (a volume, not just an area restricting gas outcome, contribute to gas leaching) one gets that Venus should be 489 times more degassed. If a true figure lies somewhere in between (62 + 489 = 551; 551: 2 = 275) and a half of the terrestrial atmosphere is buried, then 275 : 2 = 137. This also is not far from the figure 90. In any case, the understanding that Earth and Venus are not sisters but a brother and a sister may help to explain their atmospheric differencies. Ref.: [1] Kochemasov G. (1999) Geoph. Res. Abstr., V.1, #3, 700.

Kochemasov, G.

214

Dauphiné twins or not, that's the question  

NASA Astrophysics Data System (ADS)

Dauphiné twinning in trigonal low-quartz is defined by a two-fold axis (180° rotation) about the crystallographic c-axis [0001]. Dauphiné twinning has thus no effect on the orientation of the crystallographic axes of quartz, but transposes the positive and negative rhombs. Therefore, Dauphiné twinning remain undetectable by standard optical microscopy. Dauphiné twins were first resolved in euhedral quartz crystals by natural or artificial etching. In texture analysis, the different orientation distribution of the positive and negative rhombs indicates that Dauphiné twinning has likely been active within many polycrystalline quartz aggregates. Since the introduction of EBSD-OIM (SEM) Dauphiné twin boundaries can effectively be mapped in polycrystalline quartz aggregates. Dauphiné twins in quartz can be a primary microstructure, formed during crystal growth, or a secondary microstructure, resulting from transformational or mechanical twinning. Transformational Dauphiné twinning, occurring at the polymorphic transition of hexagonal high-quartz to trigonal low-quartz (573°C at atmospheric conditions), causes a variant selection through slight atomic displacements arising from internal thermal vibrations. Mechanical Dauphiné twinning in low-quartz, on the other hand, is stress-induced. It acts to align the direction of greatest elastic compliance, orthogonal to the positive rhombs, with the compressive principal stress direction. Dauphiné twin boundaries separate the two variant domains within the quartz grain. The question, though, is which of the variant domains is the 'twin' and which is the 'host'. In previous work on mechanical Dauphiné twinning in naturally deformed quartz-bearing rocks, the distinction between 'host' and 'twin' has been made mostly arbitrarily, guided by an observations bias (e.g. smallest fraction in grain represents the 'twin') or an interpretational bias (e.g. twins develop at grain boundaries). However, with respect to grains that are (nearly) free of Dauphiné twin boundaries, it is impossible to unequivocally conclude whether the grain has been (nearly) completely twinned (and should be labeled 'twin') or has remained (nearly) completely untwinned (and should be labeled 'host'). Whether or not Dauphiné twinning initiated or went to completion, largely depends on the crystallographic orientation of the quartz grain with respect to the principal stresses that have triggered mechanical Dauphiné twinning in the polycrystalline quartz aggregate. Only by means of a procedure, in which the orientation distribution of the rhombs in the individual variant domains of individual quartz grains is related to the compressive principal stresses, an attempt can be made to correctly label the different variant domains within an individual quartz grain as 'r-domains' or 'z-domains', rather than 'twin' and 'host' respectively (cf. 'r-twin' and 'z-twin' of Menegon et al., 2011). This procedure is based on the assumption that grains (nearly) free of Dauphiné twin boundaries are, on the one hand, favorably oriented with respect to the principal stresses so that twinning could easily go to completion, or, on the other hand, have a 'stable' crystallographic orientation with respect to the principal stresses, so that they remained untwinned. In both cases, these grains can be labeled as 'single r-domain grains'. We will illustrate this procedure for a sample taken from a massive quartz vein that precipitated and deformed in low-grade metamorphic conditions during the late stages of orogeny. References Menegon et al. 2011. Contribution to Mineralogy and Petrology 161, 635-652.

Sintubin, Manuel; Wenk, Hans-Rudolf

2014-05-01

215

Molecular analysis of the gut microbiota of identical twins with Crohn's disease  

SciTech Connect

Increasing evidence suggests that a combination of host genetics and the composition of the gut microbiota are important for development of Crohn's disease (CD). Our aim was to study identical twins with CD to determine microbial factors independently of host genetics. Fecal samples were studied from 10 monozygotic twin pairs with CD (discordant n=6, concordant n=4) and 8 healthy twin pairs. DNA was extracted, 16S rRNA genes were PCR amplified and T-RFLP fingerprints generated using general bacterial and Bacteroides group specific primers. The microbial communities were also profiled based on their % G+C contents. Bacteroides 16S rRNA genes were cloned and sequenced from a subset of the samples. The bacterial diversity in each sample and similarity indices between samples were estimated based on the T-RFLP data using a combination of statistical approaches. Healthy individuals had a significantly higher bacterial diversity compared to individuals with CD. The fecal microbial communities were more similar between healthy twins than between twins with CD, especially when these were discordant for the disease. The microbial community profiles of individuals with ileal CD were significantly different from healthy individuals and those with colonic CD. Also, CD individuals had a lower relative abundance of B. uniformis and higher relative abundances of B. ovatus and B. vulgatus. Our results suggest that genetics and/or environmental exposure during childhood in part determine the gut microbial composition. However, CD is associated with dramatic changes in the gut microbiota and this was particularly evident for individuals with ileal CD.

Jansson, Janet; Dicksved, Johan; Halfvarson, Jonas; Rosenquist, Magnus; Jarnerot, Gunnar; Tysk, Curt; Apajalahti, Juha; Engstrand, Lars; Jansson, Janet K.

2008-03-14

216

Healthy Eating  

NSDL National Science Digital Library

It's important to eat the right things to keep our bodies happy and healthy. As you explore these sites, look for ways you can better give your body what it needs. There's still an hour until lunch, and you're hungry. You do have a candy bar that you got for your birthday. It looks really tasty, but is that really what your body needs. Your mom always says they're bad for you, and they'll make you sick. Is that ...

Thorpe, Mr.

2012-04-30

217

Why the healing gods are twins.  

PubMed

The association of twins with health-giving powers is widespread in mythology, folklore, and religion. The Ashvins of the Rig-Veda, the classical Dioscuri, and the early Christian saints Cosmos and Damian are among the many examples of twins divinely empowered in the area of health and fertility. A characteristic set of attributes of twins recurs in different mythologies of wide distribution. In addition to healing, divine twins are often empowered with the ability to revive the dead, increase the fertility of man, animals, and crops, influence the weather, predict the future, and insure victory in battle. In some traditional societies these special attributes are thought to extend to all of the twins and their parents in the tribe.Ancient and primitive societies supposed that the birth of twins was associated with divine influence, the mother having been visited or otherwise affected by supernatural powers. A frequent explanation was that twins were the result of superfetation, a divine impregnation occurring along with that by the lawful husband. The specific powers of divine twins appear to be a reflection of the particular form of origin of twins through divine interference with the fertilization process. The twins thus share some of the powers of the divine parent, particularly those pertaining to fertility. Their dual paternity and its inherent competition is related to their martial interests as well as their ability to resolve ambivalent or ambiguous situations and predict outcomes. PMID:560764

Hankoff, L D

1977-01-01

218

Why the Healing Gods Are Twins  

PubMed Central

The association of twins with health-giving powers is widespread in mythology, folklore, and religion. The Ashvins of the Rig-Veda, the classical Dioscuri, and the early Christian saints Cosmos and Damian are among the many examples of twins divinely empowered in the area of health and fertility. A characteristic set of attributes of twins recurs in different mythologies of wide distribution. In addition to healing, divine twins are often empowered with the ability to revive the dead, increase the fertility of man, animals, and crops, influence the weather, predict the future, and insure victory in battle. In some traditional societies these special attributes are thought to extend to all of the twins and their parents in the tribe. Ancient and primitive societies supposed that the birth of twins was associated with divine influence, the mother having been visited or otherwise affected by supernatural powers. A frequent explanation was that twins were the result of superfetation, a divine impregnation occurring along with that by the lawful husband. The specific powers of divine twins appear to be a reflection of the particular form of origin of twins through divine interference with the fertilization process. The twins thus share some of the powers of the divine parent, particularly those pertaining to fertility. Their dual paternity and its inherent competition is related to their martial interests as well as their ability to resolve ambivalent or ambiguous situations and predict outcomes. PMID:560764

Hankoff, Leon D.

1977-01-01

219

Cyclic twinning in fatigued close-packed hexagonal metals  

Microsoft Academic Search

A study has been made of the behaviour of {1012} ?011? type deformation twins in fatigued cadmium, zinc, magnesium and titanium. Plastic deformation is accentuated at twin interfaces, which subsequently become serrated : the serrations are accommodated by closely spaced kink boundaries. Pre-existing twins are broken up into smaller irregularly shaped twin fragments and cracks are present at twin fragment

P. G. Partridge

1965-01-01

220

1. GENERAL VIEW OF THE LOWER END OF TWIN LAKES ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. GENERAL VIEW OF THE LOWER END OF TWIN LAKES SHOWING THE HISTORIC OUTLET WORKS AT THE EDGE OF THE WATER NEAR CENTER OF THE PHOTO WITH THE NEW TWIN LAKES DAM JUST BEHIND. VIEW LOOKING SOUTHEAST. - Twin Lakes Dam & Outlet Works, Beneath Twin Lakes Reservoir, T11S, R80W, S22, Twin Lakes, Lake County, CO

221

158. Photocopy of transit book (taken from Twin Falls Canal ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

158. Photocopy of transit book (taken from Twin Falls Canal Company Transit Book #404T, Page 3, #46, Division One). START OF MAIN CANAL SURVEY, TWIN FALLS COUNTY, MILNER, IDAHO. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

222

154. Photocopy of transit book (taken from Twin Falls Canal ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

154. Photocopy of transit book (taken from Twin Falls Canal Company Surveyor's Transit Book #405T, Page 2, #46 Division One). STATEMENT OF SIGHT-SETTING FOR 1903 SURVEY TO ALIGN SOUTH SIDE CANAL, TWIN FALLS COUNTY, MILNER, IDAHO. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

223

155. Photocopy of transit book (taken from Twin Falls Canal ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

155. Photocopy of transit book (taken from Twin Falls Canal Company Surveyor's Transit Book #405T, Page 1, #46 Division One). STATEMENT RE: SURVEY ALIGNMENT 3/03, TWIN FALLS COUNTY, MILNER, IDAHO. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

224

151. Photocopy of drawing (taken from Twin Falls Canal Company ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

151. Photocopy of drawing (taken from Twin Falls Canal Company Surveyor's Transit Book #363, Page 20). SURVEY PRINT SHOWING POINT SPILLWAY AND FIELD NOTES, TWIN FALLS COUNTY NORTHWEST OF MURTAUGH, IDAHO. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

225

152. Photocopy of drawing (taken from Twin Falls Canal Company ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

152. Photocopy of drawing (taken from Twin Falls Canal Company Surveyor's Transit Book #363, Page 1). 1912 CONDITION REPORT OF MILNER DAM AREA, TWIN FALLS COUNTY, MILNER, IDAHO. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

226

153. Photocopy of drawing (taken from Twin Falls Canal Company ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

153. Photocopy of drawing (taken from Twin Falls Canal Company Field Book #360, Page 74, entitled, 'Clay-Seam Cut-Off.' Cross-Reference: ID-15-157). MILNER DAM SURVEY, TWIN FALLS COUNTY, MILNER, IDAHO. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

227

Multiple Pregnancy Vanishing Twin Syndrome  

Microsoft Academic Search

\\u000a The vanishing twin syndrome is a relatively frequent finding, especially since the widespread use of assisted reproductive\\u000a technology (ART). Both an earlier follow-up of pregnancy and the use of transvaginal ultrasound, providing a better ultrasound\\u000a resolution, have brought us closer to the real incidence of this phenomenon, which was underestimated prior to the introduction\\u000a of these techniques. Thanks to this,

Gabriel de la Fuente; Jose Manuel Puente; Juan A. García-Velasco; Antonio Pellicer

228

Psychiatric resilience: longitudinal twin study  

PubMed Central

Objective There is great variability in response to stressful life events (SLEs), with some individuals demonstrating substantial psychiatric symptoms while others remain largely asymptomatic. The source of this variability is poorly understood. The present study aimed to examine the genetic and environmental underpinning of resilience, defined as the difference between the twins’ total score on a broad measure of internalizing symptoms and their predicted score based on their cumulative exposure to SLEs. Method SLE exposure and internalizing symptoms were assessed at two time points in 7,500 adult twins. Using the residual between actual and predicted internalizing symptom total score, twin modeling was conducted for each wave separately, as well as longitudinally. Quantitative and qualitative sex effects were also tested. Results Resilience was found to have a mild to moderate genetic heritability at each individual wave (~31%). Additionally, qualitative sex effects were found. Incorporating error of measurement into the model increased the estimated heritability for the latent construct of resilience (~50%). Unconfounded by measurement error and occasion specific effects, environmental influences contributed roughly equally to determining the individual level of resilience. Conclusions Genetic factors influence the level of psychiatric resilience, and are largely stable over time. The genes that impact on resilience are not entirely the same in males and females, although the degree of heritability is equal across the sexes. Environmental influences can also have an enduring effect on resilience. The present findings of the genetic and environmental influences on adaptation to SLEs clarify the sources of individual variation to environmental stressors. PMID:24723629

Amstadter, Ananda B.; Myers, John M.; Kendler, Kenneth S.

2014-01-01

229

Psychiatric resilience: longitudinal twin study.  

PubMed

Background The source of variability in people's response to stressful life events is poorly understood. Aims We examine the genetic and environmental underpinning of resilience (i.e. the difference between the twins' internalising symptoms and their predicted symptoms based on cumulative stressful life events). Method Stressful life event exposure and internalising symptoms were assessed at two time points in 7500 adult twins. Using the residual between actual and predicted internalising symptom total score, twin modelling was conducted for each wave separately and longitudinally. Results Resilience was found to have a moderate genetic heritability at each wave (?31%). Qualitative gender effects were found. Incorporating error of measurement into the model increased the estimated heritability for the latent construct of resilience (?50%). When measurement error and occasion-specific effects were removed, environmental influences contributed roughly equally to level of resilience. Conclusions Both genes and environment influence level of psychiatric resilience, and are largely stable over time. Environmental influences can have an enduring effect on resilience. PMID:24723629

Amstadter, Ananda B; Myers, John M; Kendler, Kenneth S

2014-10-01

230

A Novel, Homozygous c.1502T>G (p.Val501Gly) Mutation in the Thyroid peroxidase Gene in Malaysian Sisters with Congenital Hypothyroidism and Multinodular Goiter  

PubMed Central

Congenital hypothyroidism (CH) with multinodular goiter (MNG) is uncommonly seen in children. However, CH associated with goiter is often caused by defective Thyroid peroxidase (TPO) gene. In this study, we screened for mutation(s) in the TPO gene in two siblings with CH and MNG and their healthy family members. The two sisters, born to consanguineous parents, were diagnosed with CH during infancy and received treatment since then. They developed MNG during childhood despite adequate L-thyroxine replacement and negative thyroid antibody screening. PCR-amplification of all exons using flanking primers followed by DNA sequencing revealed that the two sisters were homozygous for a novel c.1502T>G mutation. The mutation is predicted to substitute valine for glycine at a highly conserved amino acid residue 501 (p.Val501Gly). Other healthy family members were either heterozygotes or mutation-free. The mutation was not detected in 50 healthy unrelated individuals. In silico analyses using PolyPhen-2 and SIFT predicted that the p.Val501Gly mutation is functionally “damaging.” Tertiary modeling showed structural alterations in the active site of the mutant TPO. In conclusion, a novel mutation, p.Val501Gly, in the TPO gene was detected expanding the mutation spectrum of TPO associated with CH and MNG. PMID:23737781

Lee, Ching Chin; Harun, Fatimah; Jalaludin, Muhammad Yazid; Heh, Choon Han; Othman, Rozana; Mat Junit, Sarni

2013-01-01

231

The effect of known cardiovascular risk factors on carotid-femoral pulse wave velocity in school-aged children: a population based twin study.  

PubMed

Childhood cardiovascular risk factors affect vascular function long before overt cardiovascular disease. Twin studies provide a unique opportunity to examine the influence of shared genetic and environmental influences on childhood cardiovascular function. We examined the relationship between birth parameters, markers of adiposity, insulin resistance, lipid profile and blood pressure and carotid-femoral pulse wave velocity (PWV), a validated non-invasive measure of arterial stiffness in a healthy cohort of school-aged twin children. PWV was performed on a population-based birth cohort of 147 twin pairs aged 7-11 years. Fasting blood samples, blood pressure and adiposity measures were collected concurrently. Mixed linear regression models were used to account for twin clustering, within- and between-twin pair associations. There were positive associations between both markers of higher adiposity, insulin resistance, elevated triglycerides and PWV, which remained significant after accounting for twin birth-set clustering. There was a positive association between both diastolic and mean arterial blood pressure and PWV in within-pair analysis in dizygotic, but not monozygotic twins, indicating genetic differences evident in dizygotic not monozygotic twins may affect these associations. Increased blood pressure, triglycerides and other metabolic markers are associated with increased PWV in school-aged twins. These results support both the genetic and environmental contribution to higher PWV, as a marker of arterial stiffness, and reiterate the importance of preventing metabolic syndrome from childhood. PMID:24965137

McCloskey, K; Sun, C; Pezic, A; Cochrane, J; Morley, R; Vuillermin, P; Burgner, D; Dwyer, T; Ponsonby, A-L

2014-08-01

232

Sister chromatid exchange test detection of toxin-induced damage in cultured fish  

E-print Network

Sister chromatid exchange test detection of toxin-induced damage in cultured fish J Lobillo JV Animals; Toulouse-Auzeville, 10-13 July 1990) sister chromatid exchange (SCE) / genotoxicity / fish the effects of these wastes on the autochthonous cultured and wild fish species of the Southern Atlantic off

Paris-Sud XI, Université de

233

SYSTEMATICS The Field Cricket Gryllus assimilis and Two New Sister Species  

E-print Network

SYSTEMATICS The Field Cricket Gryllus assimilis and Two New Sister Species (Orthoptera: Gryllidae. assimilis. KEY WORDS Gryllus, cryptic species, introduced species, sister species Gryllus Ã?eld crickets have U.S. Ã?eld crickets, whose taxonomy was settled by 1974 (Alexander 1957, Alexander and Bigelow 1960

Gray, David A.

234

The younger sisters of childbearing adolescents: their attitudes, expectations, and behaviors.  

PubMed

To examine the precursors of the disproportionately high rates of early childbearing among the younger sisters of adolescent mothers, this study compared the attitudes, expectations, and behaviors of early adolescent girls (M age = 12.93) who had an adolescent childbearing sister (n = 75) to those of early adolescent girls who had only adolescent nonchildbearing sisters (n = 348). Results indicated that the younger sisters of childbearing adolescents were consistently different from the younger sisters of nonchildbearing adolescents on key characteristics known to be correlated with early sexual activity and adolescent childbearing: that is, they were more accepting of nonmarital adolescent childbearing, perceived younger ages for typical life-course transitions (best age to get married, have first child), had more pessimistic school and career expectations, and were more likely to have engaged in problem behaviors (smoke cigarettes, skip school). These younger sister characteristics were associated with a nonvirgin sexual status in the current sample and with high closeness and high rivalry with the childbearing sister but could not be accounted for by such within-family experiences as subjects' mothers' permissiveness or lack of mother-daughter communication. Findings suggest the mechanisms by which the younger sisters of childbearing teens themselves become vulnerable to early parenthood. PMID:8625714

East, P L

1996-04-01

235

Youths' Caretaking of Their Adolescent Sisters' Children: Results from Two Longitudinal Studies  

ERIC Educational Resources Information Center

The extent and experiences of youths' caretaking of their adolescent sisters' children have been assessed in two longitudinal studies. The first study examines the caretaking patterns of 132 Latino and African American youth during middle and late adolescence. The second study involves 110 Latino youth whose teenage sister has recently given…

East, Patricia L.; Weisner, Thomas S.; Slonim, Ashley

2009-01-01

236

Brothers and Sisters of Adults with Mental Retardation: Gendered Nature of the Sibling Relationship.  

ERIC Educational Resources Information Center

Differences and similarities between 245 brothers and sisters of adults with mental retardation in the sibling relationship were examined. Sisters scored higher in the caregiving, companionship, and positive affect aspects of the sibling relationship. Sibling involvement increased over time, but was dependent upon changes in maternal health.…

Orsmond, Gael I.; Seltzer, Marsha Mailick

2000-01-01

237

Australian Twin Registry: 30 years of progress.  

PubMed

The Australian Twin Registry (ATR) is a national volunteer resource of twin pairs and higher-order multiples willing to consider participating in health, medical, and scientific research. The vision of the ATR is 'to realize the full potential of research involving twins to improve the health and well-being of all Australians'. The ATR has been funded continuously by the National Health and Medical Council for more than 30 years. Its core functions entail the recruitment and retention of twin members, the maintenance of an up-to-date database containing members' contact details and baseline information, and the promotion and provision of open access to researchers from all institutes in Australia, and their collaborators, in a fair and equitable manner. The ATR is administered by The University of Melbourne, which acts as custodian. Since the late 1970s the ATR has enrolled more than 40,000 twin pairs of all zygosities and facilitated more than 500 studies that have produced at least 700 peer-reviewed publications from classical twin studies, co-twin control studies, within-pair comparisons, twin family studies, longitudinal twin studies, randomized controlled trials, and epigenetics studies, as well as studies of issues specific to twins. New initiatives include: a Health and Life Style Questionnaire; data collection, management, and archiving using a secure online software program (The Ark); and the International Network of Twin Registries. The ATR's expertise and 30 years of experience in providing services to national and international twin studies has made it an important resource for research across a broad range of disciplines. PMID:23200298

Hopper, John L; Foley, Debra L; White, Paul A; Pollaers, Vincent

2013-02-01

238

Sisters in Science: Confronting Equity in Science and Mathematics Education  

NASA Astrophysics Data System (ADS)

The Sisters in Science (SIS) program seeks to increase elementary school girls' interest and achievement in science and mathematics, create a more positive learning climate for minority school girls and their families on academic and community/social levels, and increase the knowledge base and understanding of parents with respect to their influence in promoting girls' interest and achievement in science and mathematics. This article reports on how 577 fourth grade girls changed their interest and achievement in science and mathematics during their involvement in year 1 of the program. Findings show that the girls started the program with positive attitudes and perceptions of science and about science career possibilities. The girls significantly (p < 0.001) increased their science and mathematics skill levels after having participated in the program. It could be stated that the girls' achievement scores on the skills test increased significantly because the girls' attitudes and perceptions were positive before program implementation.

Hammrich, Penny L.; Richardson, Greer M.; Livingston, Beverly D.

239

Sororin mediates sister chromatid cohesion by antagonizing Wapl.  

PubMed

Sister chromatid cohesion is essential for chromosome segregation and is mediated by cohesin bound to DNA. Cohesin-DNA interactions can be reversed by the cohesion-associated protein Wapl, whereas a stably DNA-bound form of cohesin is thought to mediate cohesion. In vertebrates, Sororin is essential for cohesion and stable cohesin-DNA interactions, but how Sororin performs these functions is unknown. We show that DNA replication and cohesin acetylation promote binding of Sororin to cohesin, and that Sororin displaces Wapl from its binding partner Pds5. In the absence of Wapl, Sororin becomes dispensable for cohesion. We propose that Sororin maintains cohesion by inhibiting Wapl's ability to dissociate cohesin from DNA. Sororin has only been identified in vertebrates, but we show that many invertebrate species contain Sororin-related proteins, and that one of these, Dalmatian, is essential for cohesion in Drosophila. The mechanism we describe here may therefore be widely conserved among different species. PMID:21111234

Nishiyama, Tomoko; Ladurner, Rene; Schmitz, Julia; Kreidl, Emanuel; Schleiffer, Alexander; Bhaskara, Venugopal; Bando, Masashige; Shirahige, Katsuhiko; Hyman, Anthony A; Mechtler, Karl; Peters, Jan-Michael

2010-11-24

240

Telomere sister chromatid exchange in telomerase deficient murine cells  

SciTech Connect

We have recently demonstrated that several types of genomic rearrangements (i.e., telomere sister chromatid exchange (T-SCE), genomic-SCE, or end-to-end fusions) were more often detected in long-term cultured murine telomerase deficient embryonic stem (ES) cells than in freshly prepared murine splenocytes, even through they possessed similar frequencies of critically short telomeres. The high rate of genomic rearrangements in telomerase deficient ES cells, when compared to murine splenocytes, may reflect the cultured cells' gained ability to protect chromosome ends with eroded telomeres allowing them to escape 'end crisis'. However, the possibility that ES cells were more permissive to genomic rearrangements than other cell types or that differences in the microenvironment or genetic background of the animals might consequentially determine the rate of T-SCEs or other genomic rearrangements at critically short telomeres could not be ruled out.

Wang, Yisong [ORNL; Giannone, Richard J [ORNL; Liu, Yie [ORNL

2005-01-01

241

Bold vision: Catholic sisters and the creation of American hospitals.  

PubMed

American hospitals were started by religious, ethnic and community groups to serve local health care needs. Immigration into the eastern cities and the constant movement west of the frontier required the creation of educational and service facilities to serve these populations and localities. In the nineteenth century, Catholic sisters went all across the country establishing schools and hospitals. They were motivated to care for the sick, establish charitable institutions and spread their religious beliefs. Their impact on the development of the American health system was enormous. They also supported the importance of nursing for the provision of scientifically based medical care and created schools of nursing. Their historical record as founders, builders, financiers and managers of hospitals is unmatched by any other group between 1850 and 1950. And, this was accomplished at a time when women played no similar leadership and institutional ownership role elsewhere in society. PMID:21452027

Levin, Peter J

2011-06-01

242

Increased sister chromatid exchange associated with smoking and coffee consumption.  

PubMed

Sister chromatid exchange (SCE) is a very sensitive cytogenetic assay for detecting exposure to chemical mutagens and carcinogens. One application of SCE is the monitoring of populations believed to be exposed to such agents. We have, however, relatively little knowledge about common lifestyle factors that may influence SCE and therefore complicate any study designed to examine the effects of exposure to genotoxins. In this study, we assessed the effect of cigarette smoking and coffee consumption on SCE. Smoking was associated with an increase of approximately 2 SCEs per cell and a decrease in cell proliferation. A positive linear relationship between SCE and coffee consumption was also observed. This effect was similar for smokers and nonsmokers. Additionally, the folic acid content of cell culture medium seemed to affect neither SCE nor cell proliferation. PMID:3169009

Reidy, J A; Annest, J L; Chen, A T; Welty, T K

1988-01-01

243

Healthy Water Healthy People Field Monitoring Guide  

ERIC Educational Resources Information Center

This 100-page manual serves as a technical reference for the "Healthy Water, Healthy People Water Quality Educators Guide" and the "Healthy Water Healthy People Testing Kits". Yielding in-depth information about ten water quality parameters, it answers questions about water quality testing using technical overviews, data interpretation guidelines,…

Project WET Foundation, 2003

2003-01-01

244

Atomistic deformation mechanisms in twinned copper nanospheres  

PubMed Central

In the present study, we perform molecular dynamic simulations to investigate the compression response and atomistic deformation mechanisms of twinned nanospheres. The relationship between load and compression depth is calculated for various twin spacing and loading directions. Then, the overall elastic properties and the underlying plastic deformation mechanisms are illuminated. Twin boundaries (TBs) act as obstacles to dislocation motion and lead to strengthening. As the loading direction varies, the plastic deformation transfers from dislocations intersecting with TBs, slipping parallel to TBs, and then to being restrained by TBs. The strengthening of TBs depends strongly on the twin spacing. PMID:25024693

2014-01-01

245

Self-replicating twins in nanowires.  

PubMed

Based on molecular-dynamics simulations validated with quantum-mechanical calculations, we predict that (111) twin planes in a [111]-oriented GaAs nanowire attain attractive interactions mediated by surface strain. This gives rise to a self-replication mechanism that continuously generates a twin superlattice in a nanowire during growth. We demonstrate significant implications of the twin-twin interaction for the electronic, mechanical, and chemical properties of nanowires. These unique properties suggest potential applications such as catalysts for solar fuel production and nanoscale mechanical dampers. PMID:24073636

Yuan, Zaoshi; Nakano, Aiichiro

2013-10-01

246

Psychosexual study of communist era Hungarian twins.  

PubMed

Our aim in this study is to describe the characteristics of sexual development in twins and estimate the role of heritability and environmental factors as causes of certain sexual disorders. Two hundred and ten adult same-sex twin pairs (92 monozygotic [MZ] female, 41 MZ male, 55 dizygotic [DZ] female and 22 DZ male pairs) were involved in the study. Data were collected in 1982 by self-administered questionnaires that included items on sexual maturation, sexual life, contraception, mutual sexual activity within twin pairs and alcohol use. The ratio of married to unmarried twins was nearly the same in MZs and DZs, with the exception that the divorce rate was higher in MZ female twins (14%), and DZ and male twins were slightly more likely to be single. Menarche was later in twins compared to non-twin Hungarian women. 57% of MZs experienced menarche within 3 months of each other, 77% within 6 months while it occurred for 30% and 43% respectively in DZs. The first seminal emission indicated some delay in male twins compared with the Hungarian general population sample. MZ first kisses occurred later than DZ's first kisses. The same was true for the first petting, masturbation and first sexual intercourse. Anorgasmy is 27% heritable but the estimate is not statistically significant. Concordance rate for premature ejaculation in MZs was greater than in DZs but the structural equation model showed significant misfit. Age at menarche appeared to be strongly heritable. PMID:21425896

Metneki, Julia; Tarnoki, Adam Domonkos; Tarnoki, David Laszlo; Littvay, Levente; Czeizel, Andrew

2011-04-01

247

The nanostructured origin of deformation twinning.  

PubMed

We have revealed the fundamental embryonic structure of deformation twins using in situ mechanical testing of magnesium single crystals in a transmission electron microscope. This structure consists of an array of twin-related laths on the scale of several nanometers. A computational model demonstrates that this structure should be a generic feature at the incipient stage of deformation twinning when there are correlated nucleation events. Our results shed light on the origin of twinning-induced plasticity and transformation toughening, critical to the development of advanced structural alloys with high strength, ductility, and toughness. PMID:22239446

Yu, Qian; Qi, Liang; Chen, Kai; Mishra, Raja K; Li, Ju; Minor, Andrew M

2012-02-01

248

Common plankton of Twin Lakes, Colorado  

SciTech Connect

A series of studies is being performed to evaluate the effects of the Mt. Elbert Pumped-Storage Powerplant on the ecology of Twin Lakes. Twin Lakes are a pair of connected dimictic lakes, formed as the result of glacial action on alluvial deposits. This report presents a taxonomic species study of the common plankton collected since 1974 from Twin Lakes. A total of 11 zooplankters and 14 phytoplankters were identified from the limnetic zone of Twin Lakes and the associated Mt. Elbert Forebay. The four divisions of zooplankton included four species of Rotifera (rotifer), three species of Copepoda (copepod), three species of Cladocera (cladoceran), and one species of Mysidacea (opossum shrimp).

Lieberman, D.M.

1983-02-01

249

Twin-Twin Transfusion Syndrome The Influence of Intrauterine Laser Photocoagulation on Arterial Distensibility in Childhood  

Microsoft Academic Search

Background—In twin-twin transfusion syndrome (TTTS), the donor and recipient fetus are exposed to differing volume loads and show discordant intertwin vascular compliance in childhood despite identical genotype. We hypothesized that discordance is prevented by intrauterine endoscopic laser ablation of placental anastomoses, which abolishes intertwin transfusion. We tested this by examining pulse wave velocity (PWV) in brachial arteries of twin survivors

Helena M. Gardiner; Myles J. O. Taylor; Ageliki Karatza; Tina Vanderheyden; Agnes Huber; Stephen E. Greenwald; Nicholas M. Fisk; Kurt Hecher

250

Renal failure in the surviving monochorionic twin after death of the co-twin in utero  

Microsoft Academic Search

Renal failure in the newborn infant is mainly determined by vascular causes. In this report we describe a patient with a particular vascular cause of renal failure. The patients was the product of a twin pregnancy in which the twin partner died in utero. In retrospect, the twins appeared to be monozygotic. As the pregnancy was studied carefully prenatally by

Arno F. J. van Heijstl; Jan G. Nijhuis; Peter Bult; Christina A. Hulsbergen-van de Kaa; Leo A. H. Monnens; Ben A. Semmekrot

1996-01-01

251

The geography and ecology of plant speciation: range overlap and niche divergence in sister species.  

PubMed

A goal of evolutionary biology is to understand the roles of geography and ecology in speciation. The recent shared ancestry of sister species can leave a major imprint on their geographical and ecological attributes, possibly revealing processes involved in speciation. We examined how ecological similarity, range overlap and range asymmetry are related to time since divergence of 71 sister species pairs in the California Floristic Province (CFP). We found that plants exhibit strikingly different age-range correlation patterns from those found for animals; the latter broadly support allopatric speciation as the primary mode of speciation. By contrast, plant sisters in the CFP were sympatric in 80% of cases and range sizes of sisters differed by a mean of 10-fold. Range overlap and range asymmetry were greatest in younger sisters. These results suggest that speciation mechanisms broadly grouped under 'budding' speciation, in which a larger ranged progenitor gives rise to a smaller ranged derivative species, are probably common. The ecological and reproductive similarity of sisters was significantly greater than that of sister-non-sister congeners for every trait assessed. However, shifts in at least one trait were present in 93% of the sister pairs; habitat and soil shifts were especially common. Ecological divergence did not increase with range overlap contrary to expectations under character displacement in sympatry. Our results suggest that vicariant speciation is more ubiquitous in animals than plants, perhaps owing to the sensitivity of plants to fine-scale environmental heterogeneity. Despite high levels of range overlap, ecological shifts in the process of budding speciation may result in low rates of fine-scale spatial co-occurrence. These results have implications for ecological studies of trait evolution and community assembly; despite high levels of sympatry, sister taxa and potentially other close relatives, may be missing from local communities. PMID:24452025

Anacker, Brian L; Strauss, Sharon Y

2014-03-01

252

Sisters Together: Move More, Eat Better Energize Yourself  

E-print Network

and eat better?............................................ 2 How much physical activity do I need? ................................. 3 How can I handle barriers to becoming more physically active know? Eating healthy foods and staying physically active can help you keep up with the demands of your

Rau, Don C.

253

Growth of deformation twins in tantalum via coherent twin boundary migration  

NASA Astrophysics Data System (ADS)

In order to investigate the process of twinning growth, the nucleation of twinning dislocation loops on the coherent boundary of a Tantalum twin superlattice is studied via a molecular dynamics approach. We get homogeneous nucleation rates by means of a stationarity test and the mean first-passage method. We study their dependence on driving force and temperature in a framework given by the Kolgomorov-Johnson-Mehl-Avrami theory. Correspondingly, the contribution to the twinning growth dictated by this nucleation mechanism, as compared to the pole mechanism, is discussed. The homogeneous loop nucleation and growth mechanism can be relevant to twinning in high strain-rate experiments as in shock waves.

Sandoval, Luis A.; Surh, Michael P.; Chernov, Alexander A.; Richards, David F.

2013-09-01

254

Twin-Foucault imaging method  

NASA Astrophysics Data System (ADS)

A method of Lorentz electron microscopy, which enables observation two Foucault images simultaneously by using an electron biprism instead of an objective aperture, was developed. The electron biprism is installed between two electron beams deflected by 180° magnetic domains. Potential applied to the biprism deflects the two electron beams further, and two Foucault images with reversed contrast are then obtained in one visual field. The twin Foucault images are able to extract the magnetic domain structures and to reconstruct an ordinary electron micrograph. The developed Foucault method was demonstrated with a 180° domain structure of manganite La0.825Sr0.175MnO3.

Harada, Ken

2012-02-01

255

Simultaneous subependymomas in monozygotic female twins: further evidence for a common genetic or developmental disorder background.  

PubMed

In this paper, a rare case of subependymoma of the fourth ventricle in identical female twins is reported. Magnetic resonance imaging and CT showed nearly identical locations of the tumors in the fourth ventricle and similar growth patterns of the tumors in both sisters. Likewise, postoperative histopathological analysis of both tumors revealed the typical histological appearance of subependymomas. Subependymoma is a rare, low-grade glioma of the CNS, slowly growing and usually asymptomatic. If symptomatic, a subependymoma can in some cases lead to sudden death caused by pressure on the brainstem or decompensated secondary hydrocephalus. This case demonstrates the importance of detecting tumors early and thereby preventing symptoms arising from increasing intracranial pressure, and optimizing therapy options. PMID:24655099

Noell, Susan; Beschorner, Rudi; Bisdas, Sotirios; Beyer, Ulrike; Weber, Ruthild G; Fallier-Becker, Petra; Ritz, Rainer

2014-09-01

256

Clinical and echographic features of in utero cardiac dysfunction in the recipient twin in twin-twin transfusion syndrome.  

PubMed Central

OBJECTIVE--Fetal twin-twin transfusion syndrome (TTTS) presenting in the second trimester has been associated with almost no perinatal survival until recently, when serial drainage of amniotic fluid has improved the prognosis to 70%-80%. Most recipient twins now survive but develop cardiac dysfunction. The study was undertaken to evaluate the abnormal echocardiographic features and clinical complications of cardiac disease in the recipient twin of TTTS. DESIGN--Antenatal and postnatal echocardiographic and clinical observational study. SETTING--Antenatal studies in a tertiary referral centre. Postnatal management and follow up were performed by the same paediatric cardiologist, either at the obstetric hospital or at the regional referral centre. PATIENTS--Twin pregnancies complicated by TTTS with severe polyhydramnios diagnosed earlier than 25 weeks that proceeded until viability (n = 5). INTERVENTION--Serial fetal echocardiography with colour Doppler. Postnatal echocardiography in the first week and between two and seven months. Serial amnioreduction was performed in all pregnancies. Digoxin treatment, pericardiocentesis, paracentesis, or laser ablation of placental anastomoses was undertaken when there was hydrops. RESULTS--Increased cardiothoracic ratio and tricuspid regurgitation were seen in all recipient twins. High pulmonary artery velocities developed in three. One recipient twin died a week after delivery of endocardial fibroelastosis and infundibular pulmonary stenosis. Two other had balloon dilatation for pulmonary stenosis, one shortly after birth and one at four months. A further twin has apical thickening of the right ventricle at six months. The remaining recipient twin had normal echocardiographic findings at follow up. CONCLUSION--This report characterises for the first time a cardiac disease acquired in utero in the recipient twin in pregnancies complicated by TTTS. Clinical manifestations in utero range from mild to critical pulmonary stenosis or lethal cardiomyopathy. Although perinatal prognosis seems to be related to the severity of dysfunction when first diagnosed in utero, follow up in infancy is recommended in view of the possibility of progressive pulmonary stenosis. Images PMID:8068474

Zosmer, N; Bajoria, R; Weiner, E; Rigby, M; Vaughan, J; Fisk, N M

1994-01-01

257

NOTE: Haemodynamic resistance model of monochorionic twin pregnancies complicated by acardiac twinning  

NASA Astrophysics Data System (ADS)

An acardiac twin is a severely malformed monochorionic twin fetus that lacks most organs, particularly a heart. It grows during pregnancy, because it is perfused by its developmentally normal co-twin (called the pump twin) via a set of placental arterioarterial and venovenous anastomoses. The pump twin dies intrauterine or neonatally in about 50% of the cases due to congestive heart failure, polyhydramnios and prematurity. Because the pathophysiology of this pregnancy is currently incompletely understood, we modified our previous haemodynamic model of monochorionic twins connected by placental vascular anastomoses to include the analysis of acardiac twin pregnancies. We incorporated the fetoplacental circulation as a resistance circuit and used the fetal umbilical flow that perfuses the body to define fetal growth, rather than the placental flow as done previously. Using this modified model, we predicted that the pump twin has excess blood volume and increased mean arterial blood pressure compared to those in the acardiac twin. Placental perfusion of the acardiac twin is significantly reduced compared to normal, as a consequence of an increased venous pressure, possibly implying reduced acardiac placental growth. In conclusion, the haemodynamic analysis may contribute to an increased knowledge of the pathophysiologic consequences of an acardiac body mass for the pump twin.

Umur, Asli; van Gemert, Martin J. C.; van den Wijngaard, Jeroen P. H. M.; Ross, Michael G.; Nikkels, Peter G. J.

2004-07-01

258

Attractiveness Differences Between Twins Predicts Evaluations of Self and Co-Twin  

PubMed Central

One of the most consistent findings in psychology shows that people prefer and make positive attributions about attractive compared with unattractive people. The goal of the current study was to determine the power of attractiveness effects by testing whether these social judgments are made where attractiveness differences are smallest: between twins. Differences in facial attractiveness predicted twins’ evaluations of self and their co-twin (n = 158; 54 male). In twin pairs, the more attractive twin judged their less attractive sibling as less physically attractive, athletic, socially competent, and emotionally stable. The less attractive twin did the reverse. Given that even negligible differences in facial attractiveness predicted self and co-twin attitudes, these results provide the strongest test yet of appearance-based stereotypes. PMID:23467329

Principe, Connor P.; Rosen, Lisa H.; Taylor-Partridge, Teresa; Langlois, Judith H.

2012-01-01

259

Not really identical: epigenetic differences in monozygotic twins and implications for twin studies in psychiatry.  

PubMed

Classical twin studies in the field of psychiatry generally fall into one of two categories: (1) those designed to identify environmental risk factors causing discordance in monozygotic (MZ) twins and (2) those geared towards identifying genetic risk factors. However, neither environment nor differences in DNA sequence can fully account for phenotypic discordance among MZ twins. The field of epigenetics--DNA modifications that can affect gene expression--offers new models to understand discordance in MZ twins. In the past, MZ twins were regarded as genetically-identical controls for differing environmental conditions. In contrast, the evolving current concept is that epigenetic differences between MZ twins may modulate differences in diverse phenotype, from disease to personality. In this article, we review some twin studies, and discuss the dynamic interactions between stochastic, environmental, and epigenetic variables that influence neurobiological phenotypes. PMID:19378334

Haque, F Nipa; Gottesman, Irving I; Wong, Albert H C

2009-05-15

260

49 CFR 372.221 - Twin Cities.  

Code of Federal Regulations, 2011 CFR

...2011-10-01 2011-10-01 false Twin Cities. 372.221 Section 372.221 Transportation... Commercial Zones § 372.221 Twin Cities. For the purpose of determining...each of the following combinations of cities shall be considered as a single...

2011-10-01

261

49 CFR 372.221 - Twin Cities.  

Code of Federal Regulations, 2013 CFR

...2013-10-01 2013-10-01 false Twin Cities. 372.221 Section 372.221 Transportation... Commercial Zones § 372.221 Twin Cities. For the purpose of determining...each of the following combinations of cities shall be considered as a single...

2013-10-01

262

49 CFR 372.221 - Twin Cities.  

Code of Federal Regulations, 2012 CFR

...2012-10-01 2012-10-01 false Twin Cities. 372.221 Section 372.221 Transportation... Commercial Zones § 372.221 Twin Cities. For the purpose of determining...each of the following combinations of cities shall be considered as a single...

2012-10-01

263

49 CFR 372.221 - Twin Cities.  

Code of Federal Regulations, 2010 CFR

...2010-10-01 2010-10-01 false Twin Cities. 372.221 Section 372.221 Transportation... Commercial Zones § 372.221 Twin Cities. For the purpose of determining...each of the following combinations of cities shall be considered as a single...

2010-10-01

264

Transabdominal ultrasonography diagnosis of ectopic twin gestation  

Microsoft Academic Search

The coexistence of ectopic and intrauterine pregnancy is rare; presence of ectopic twin is even less frequent. We report a rare case of live ectopic tubal twin gestation, which detected preoperatively at 11 weeks of gestation by transabdominal sonography, when patient experienced severe lower abdominal pain.

Gamanagatti Shivanand; Deep Narayana Srivastava; Hiralal; S. Subramanian

2004-01-01

265

"The Bell Curve" on Separated Twins.  

ERIC Educational Resources Information Center

"The Bell Curve" declares that studies of separated identical twins--the "purest" of "direct" methods for estimating IQ heritability--indicate a value of +.75-+.80. But, the main study cited suggests a heritability of "two-thirds" for the middle class, and Herrnstein and Murray neglect to mention numerous complicating factors in twin studies that…

Fancher, Raymond E.

1995-01-01

266

Mental and motor development in infant twins  

Microsoft Academic Search

Used the Bayley Scales of Infant Development to evaluate the mental and motor development of 261 pairs of twins at 3, 6, 9, 12, 18 and 24 mo. of age. Results show that with a small allowance for prematurity, the twins displayed essentially the same rate of progression in development as singletons. The correlations between developmental scores obtained at successive

Ronald S. Wilson; Eileen B. Harpring

1972-01-01

267

TWINS Observations of Oxygen ENA Flux  

Microsoft Academic Search

As part of the science objectives of the TWINS (Two Wide-angle Imaging Neutral-atom Spectrometers) mission, we aim to enhance the knowledge of the workings of our magnetosphere by contributing compositional information of the observed energetic neutral atom (ENA) flux from the two TWINS instruments. We will present images of oxygen (O) ENA flux varying over time and space. Results from

J. C. Alquiza; J. Goldstein; M. Gruntman; D. J. McComas; J. Redfern; P. W. Valek

2009-01-01

268

Colorado Longitudinal Twin Study of Reading Disability  

ERIC Educational Resources Information Center

The primary objectives of the present study are to introduce the Colorado Longitudinal Twin Study of Reading Disability, the first longitudinal twin study in which subjects have been specifically selected for having a history of reading difficulties, and to present some initial assessments of the stability of reading performance and cognitive…

Wadsworth, Sally J.; DeFries, John C.; Olson, Richard K.; Willcutt, Erik G.

2007-01-01

269

GLOBALIZATION AND THE TWIN PROTECTIONS Juillet 2007  

E-print Network

GLOBALIZATION AND THE TWIN PROTECTIONS N° 2007-21 Juillet 2007 Collection OFCE/ANR n°1 JEAN-PAUL FITOUSSI #12;Globalization and the Twin Protections Jean-Paul Fitoussi* Summary The aim of this short paper is to devise policies to avoid that the present course of globalization becomes so unstable that it would lead

Paris-Sud XI, Université de

270

Chromosome orientation fluorescence in situ hybridization (CO-FISH) to study sister chromatid segregation in vivo  

PubMed Central

Previously, assays for sister chromatid segregation patterns relied on incorporation of BrdU and indirect methods to infer segregation patterns after two cell divisions. Here we describe a method to differentially label sister chromatids of murine cells and directly assay sister chromatid segregation patterns following one cell division in vitro and in vivo by adaptation of the well-established CO-FISH (chromosome orientation fluorescent in situ hybridization) technique. 5-bromo-2?-deoxyuridine (BrdU) is incorporated into newly-formed DNA strands, followed by photolysis and exonuclease digestion to create single-stranded sister chromatids containing parental template DNA only. Such single-stranded sister chromatids are differentially labeled using unidirectional probes to major satellite sequences coupled to fluorescent markers. Differentially-labeled sister chromatids in post-mitotic cells are visualized using fluorescence microscopy and sister chromatid segregation patterns can be directly assayed after one cell division. This procedure requires four days for in vivo mouse tissues, and two days for in vitro cultured cells. PMID:20595964

Falconer, Ester; Chavez, Elizabeth; Henderson, Alexander; Lansdorp, Peter M.

2013-01-01

271

Anisotropy in twinned terfenol-D crystals  

NASA Astrophysics Data System (ADS)

The highly magnetostrictive cubic compound Terfenol-D (Tb0.3Dy0.7Fe2) solidifies via a (211) dendritic growth front when growth by a free-standing zone technique. The resulting material is usually composed of dendritic plates often containing crystallographic twins, the predominant plate and twin plane being the (1-11) orthogonal to the (-2-11) growth plane. Results of room temperature magnetic torque analysis from (011) disk specimens, having differing twin densities, are presented which yield both the magnetic anisotropy constants, K(sub 1) = -1.6 x 10(exp 5) J/cu m and K(sub 2) = -0.16 x 10(exp 5) J/cu m, and the relative parent/twin volume. Magnetic susceptibility data both parallel and transverse to the applied field are presented which, in conjunction with the anisotropy results, emphasize the importance of twin density on magnetoelastic response for typical application geometries.

Lord, D. G.; Harvey, D.

1994-11-01

272

Niobium and tantalum: indispensable twins  

USGS Publications Warehouse

Niobium and tantalum are transition metals almost always paired together in nature. These “twins” are difficult to separate because of their shared physical and chemical properties. In 1801, English chemist Charles Hatchett uncovered an unknown element in a mineral sample of columbite; John Winthrop found the sample in a Massachusetts mine and sent it to the British Museum in London in 1734. The name columbium, which Hatchet named the new element, came from the poetic name for North America—Columbia—and was used interchangeably for niobium until 1949, when the name niobium became official. Swedish scientist Anders Ekberg discovered tantalum in 1802, but it was confused with niobium, because of their twinned properties, until 1864, when it was recognized as a separate element. Niobium is a lustrous, gray, ductile metal with a high melting point, relatively low density, and superconductor properties. Tantalum is a dark blue-gray, dense, ductile, very hard, and easily fabricated metal. It is highly conductive to heat and electricity and renowned for its resistance to acidic corrosion. These special properties determine their primary uses and make niobium and tantalum indispensable.

Schulz, Klaus; Papp, John

2014-01-01

273

Two sisters in the same dress: Heliconius cryptic species  

PubMed Central

Background Sister species divergence and reproductive isolation commonly results from ecological adaptation. In mimetic Heliconius butterflies, shifts in colour pattern contribute to pre- and post-mating reproductive isolation and are commonly correlated with speciation. Closely related mimetic species are therefore not expected, as they should lack several important sources of reproductive isolation. Results Here we present phenotypic, behavioral and genetic evidence for the coexistence of two sympatric 'cryptic' species near Florencia in the eastern Andes of Colombia that share the same orange rayed colour pattern. These represent H. melpomene malleti and a novel taxon in the H. cydno group, here designated as novel race of Heliconius timareta, Heliconius timareta florencia. No-choice mating experiments show that these sympatric forms have strong assortative mating (?96%) despite great similarity in colour pattern, implying enhanced divergence in pheromonal signals. Conclusion We hypothesize that these species might have resulted from recent convergence in colour pattern, perhaps facilitated by hybrid introgression of wing pattern genes. PMID:19040737

2008-01-01

274

Newly discovered sister lineage sheds light on early ant evolution  

PubMed Central

Ants are the world's most conspicuous and important eusocial insects and their diversity, abundance, and extreme behavioral specializations make them a model system for several disciplines within the biological sciences. Here, we report the discovery of a new ant that appears to represent the sister lineage to all extant ants (Hymenoptera: Formicidae). The phylogenetic position of this cryptic predator from the soils of the Amazon rainforest was inferred from several nuclear genes, sequenced from a single leg. Martialis heureka (gen. et sp. nov.) also constitutes the sole representative of a new, morphologically distinct subfamily of ants, the Martialinae (subfam. nov.). Our analyses have reduced the likelihood of long-branch attraction artifacts that have troubled previous phylogenetic studies of early-diverging ants and therefore solidify the emerging view that the most basal extant ant lineages are cryptic, hypogaeic foragers. On the basis of morphological and phylogenetic evidence we suggest that these specialized subterranean predators are the sole surviving representatives of a highly divergent lineage that arose near the dawn of ant diversification and have persisted in ecologically stable environments like tropical soils over great spans of time. PMID:18794530

Rabeling, Christian; Brown, Jeremy M.; Verhaagh, Manfred

2008-01-01

275

FANCC suppresses short telomere-initiated telomere sister chromatid exchange.  

PubMed

Telomere shortening has been linked to rare human disorders that present with bone marrow failure including Fanconi anemia (FA). FANCC is one of the most commonly mutated FA genes in FA patients and the FANCC subtype tends to have a relatively early onset of bone marrow failure and hematologic malignancies. Here, we studied the role of Fancc in telomere length regulation in mice. Deletion of Fancc (Fancc(-/-)) did not affect telomerase activity, telomere length or telomeric end-capping in a mouse strain possessing intrinsically long telomeres. However, ablation of Fancc did exacerbate telomere attrition when murine bone marrow cells experienced high cell turnover after serial transplantation. When Fancc(-/-) mice were crossed into a telomerase reverse transcriptase heterozygous or null background (Tert(+/-) or Tert(-/-)) with short telomeres, Fancc deficiency led to an increase in the incidence of telomere sister chromatid exchange. In contrast, these phenotypes were not observed in Tert mutant mice with long telomeres. Our data indicate that Fancc deficiency accelerates telomere shortening during high turnover of hematopoietic cells and promotes telomere recombination initiated by short telomeres. PMID:20022886

Rhee, David B; Wang, Yisong; Mizesko, Melissa; Zhou, Fang; Haneline, Laura; Liu, Yie

2010-03-01

276

Ecologically distinct dinosaurian sister group shows early diversification of Ornithodira.  

PubMed

The early evolutionary history of Ornithodira (avian-line archosaurs) has hitherto been documented by incomplete (Lagerpeton) or unusually specialized forms (pterosaurs and Silesaurus). Recently, a variety of Silesaurus-like taxa have been reported from the Triassic period of both Gondwana and Laurasia, but their relationships to each other and to dinosaurs remain a subject of debate. Here we report on a new avian-line archosaur from the early Middle Triassic (Anisian) of Tanzania. Phylogenetic analysis places Asilisaurus kongwe gen. et sp. nov. as an avian-line archosaur and a member of the Silesauridae, which is here considered the sister taxon to Dinosauria. Silesaurids were diverse and had a wide distribution by the Late Triassic, with a novel ornithodiran bauplan including leaf-shaped teeth, a beak-like lower jaw, long, gracile limbs, and a quadrupedal stance. Our analysis suggests that the dentition and diet of silesaurids, ornithischians and sauropodomorphs evolved independently from a plesiomorphic carnivorous form. As the oldest avian-line archosaur, Asilisaurus demonstrates the antiquity of both Ornithodira and the dinosaurian lineage. The initial diversification of Archosauria, previously documented by crocodilian-line archosaurs in the Anisian, can now be shown to include a contemporaneous avian-line radiation. The unparalleled taxonomic diversity of the Manda archosaur assemblage indicates that archosaur diversification was well underway by the Middle Triassic or earlier. PMID:20203608

Nesbitt, Sterling J; Sidor, Christian A; Irmis, Randall B; Angielczyk, Kenneth D; Smith, Roger M H; Tsuji, Linda A

2010-03-01

277

Detection of sister chromatid exchanges induced by volatile genotoxicants  

SciTech Connect

To test the recently developed method of exposing cells to volatile compounds, phytohemagglutinin-stimulated human peripheral lymphocyte cultures were exposed to gaseous methyl bromide, ethylene oxide, and propylene oxide, as well as diesel exhaust. The cultures were placed in sterile dialysis tubing and inserted into enclosed flasks containing additional culture medium. The test compounds (in gaseous state) were diluted with air and bubbled through the flasks for various lengths of time. The cells were then washed and incubated for a total of 75 h. The harvest was performed according to established procedures, and second-division cells were scored for induction of sister chromatid exchanges (SCEs). The SCE frequency was more than doubled in the cultures treated with ethylene oxide and propylene oxide; methyl bromide also induced SCEs. Cultures treated with diesel exhaust showed an increase in the SCE frequency in cells from two of four donors tested. These results further substantiate the use of this method for detecting the induction of SCEs by airborne genotoxins.

Tucker, J.D.; Xu, J.; Stewart, J.; Baciu, P.C.; Ong, T.M.

1986-01-01

278

NOTE: Modelling the influence of amnionicity on the severity of twin twin transfusion syndrome in monochorionic twin pregnancies  

NASA Astrophysics Data System (ADS)

Clinical treatment for diamniotic monochorionic twin twin transfusion syndrome (TTTS) may include conversion of diamniotic pregnancies to a monoamniotic monochorionic state by disrupting the amnion septum. We sought to test the underlying hypothesis, i.e. that a monoamniotic state reduces the severity of TTTS. With use of our previously developed mathematical model of two equal fetoplacental circulatory units connected by various sizes and types of placental anastomoses, we compared the haemodynamic and amniotic fluid dynamics of monoamniotic and diamniotic twins that develop TTTS. We used three anastomotic patterns that produce severe, moderate or mild forms of TTTS, respectively, in our diamniotic monochorionic twin model. Monoamnionicity was modelled by adding the two amniotic fluid volumes and using the volume-averaged amniotic fluid osmolality. The results were as follows: for severe TTTS, small differences develop between diamniotic and monoamniotic donor twins in fetal urine production, swallowed volume, blood volume, blood pressures, net fetofetal transfusion, and blood and amniotic fluid osmolality. However, the circulatory imbalance between the monoamniotic twins deteriorates similar to that of diamniotic twins. The pathophysiological differences tend to disappear for milder TTTS. In conclusion, our model suggests that the uncommon finding of TTTS in monoamniotic twins is not due to the presence of a single amniotic sac. Rather, clinically significant differences in anastomotic patterns and the delayed or lack of identification of manifestations in monoamniotic twins account for the reduced rate of TTTS diagnosis. Based on these results we expect the clinical disruption of the amnion septum in diamniotic monochorionic TTTS pregnancies to have only minimal benefits.

van den Wijngaard, Jeroen P. H. M.; Umur, Asli; Ross, Michael G.; van Gemert, Martin J. C.

2004-03-01

279

NOTE: Thrombosis of anastomoses may affect the staging sequence of twin twin transfusion syndrome  

NASA Astrophysics Data System (ADS)

Twin-twin transfusion syndrome (TTTS) is a severe complication of monozygotic (identical) twins, which share one single monochorionic placenta. It is caused by placental anastomoses which link the two fetoplacental circulations of the twins and allow a chronic net inter-twin transfusion to develop between the fetuses. Clinical presentation of TTTS manifestations has been classified into five different stages. In this paper, we used our computational model of TTTS and examined the possible differences between chronic and rapidly increasing inter-twin transfusion in the simulated TTTS staging sequence. Our results suggest that rapid alterations in the net inter-twin transfusion, e.g. due to thrombosis of placental anastomoses, may produce a different staging sequence than in TTTS caused by chronic inter-twin transfusion. These results may aid an improved knowledge of TTTS pathophysiology under conditions of a rapidly changing cardiovascular function, and contribute to the planning of optimal intervention under such circumstances. Supported in part by the European Community Euro-twin-2-twin project (JPHMvdW) and by the National Institutes of Health, grant HL40899 (MGR).

van den Wijngaard, Jeroen P. H. M.; Ross, Michael G.; van Gemert, Martin J. C.

2008-03-01

280

Keeping Your Voice Healthy  

MedlinePLUS

Keeping Your Voice Healthy Keeping Your Voice Healthy Patient Health Information News media interested in covering the latest from AAO-HNS/ ... heavily voice-related. Key Steps for Keeping Your Voice Healthy Drink plenty of water. Moisture is good ...

281

Healthy Eating for Preschoolers  

MedlinePLUS

Healthy Eating Get your child on the path to healthy eating. Focus on the meal and each other. Your ... child’s throat—about the size of a nickel. Healthy Eating There are many ways to divide the Daily ...

282

Eating Healthy Ethnic Food  

MedlinePLUS

... Parents/Families ( We Can! ) Health Professional Resources Tipsheet: Eating Healthy Ethnic Food Trying different ethnic cuisines to ... Aim for a Healthy Weight Pocket Guide to Eating Healthy on the Go features tips on ordering ...

283

Maintaining a Healthy Weight  

MedlinePLUS

... and drink Other ways to maintian a healthy weight? Limit portion size to control calorie intake. Add ... Go4Life Maintaining a Healthy Weight Maintaining a healthy weight is important for overall health and well-being. ...

284

Increased UV-induced sister-chromatid exchange in cultured fibroblasts of first-degree relatives of melanoma patients  

SciTech Connect

Cultured fibroblasts of 17 first-degree relatives of familial melanoma patients and six first-degree relatives of cutaneous melanoma (CMM) patients with multiple CMM primaries were tested for in vitro sensitivity to UV light. Fibroblasts of nine familial CMM patients with a known UV-sensitivity and 19 healthy probands served as a control. Sister chromatid exchange (SCE) was used as a parameter to detect UV-induced genotoxic damage. The authors found significantly (p less than 0.001) increased UV-induced SCE levels in familial melanoma patients, as well as in first-degree relatives of familial melanoma patients (p less than 0.001) after UV-A,B irradiation (375 J/m2), compared to the healthy probands without a family history of CMM. A significant (p less than 0.001) increase of UV-induced SCE was also observed in the relatives of CMM patients with multiple CMM primaries. In addition, the spontaneous SCE were significantly increased (p less than 0.05) in familial CMM patients. This study shows that increased UV sensitivity is a familial phenomenon. It is consistent with the concept of a genetic predisposition to CMM, which is based on increased UV sensitivity and may help to define groups with an elevated risk of developing cutaneous malignant melanoma.

Knees-Matzen, S.; Roser, M.; Reimers, U.; Ehlert, U.; Weichenthal, M.; Breitbart, E.W.; Ruediger, H.W. (Department of Occupational Medicine, University of Hamburg (Germany))

1991-06-01

285

Structural interpretation of the nucleation and growth of deformation twins in Zr and Ti--2: TEM study of twin morphology and defect reactions during twinning  

SciTech Connect

A TEM study of mechanical twinning in Ti and Zr was performed. A large number of [0001]-dislocations which are rarely seen in the matrix, and a new type of stacking fault were found within deformation twins in both materials. Matrix dislocations were observed to actively interact with the tips of twin embryos and step ledges of growing twin lamellae. Twin embryos bounded by straight coherent and inclined semi-coherent boundaries were observed. These results as well as the morphological variation of twin lamellae during deformation do not agree with twinning dislocation theories but support a step-wise nucleation and growth mechanism proposed for deformation twinning in h.c.p. structures. Extended discussions are provided to address unanswered questions in the literature concerning deformation twinning.

Song, S.G.; Gray, G.T. III [Los Alamos National Lab., NM (United States)] [Los Alamos National Lab., NM (United States)

1995-06-01

286

The Sri Lankan Twin Registry: 2012 update.  

PubMed

The Sri Lankan Twin Registry (SLTR), established in 1997, is a unique resource for twin and genetic research in a low- and middle-income country (LMIC). It comprises of a volunteer cohort of 14,120 twins (7,060 pairs) and 119 sets of triplets, and a population-based cohort of 19,040 (9,520 pairs) twins and 89 sets of triplets. Several studies have been conducted using this registry, including the Colombo Twin and Singleton Study (CoTaSS 1; 4,387 twins, 2,311 singletons), which have explored the prevalence and heritability of a range of psychiatric disorders as well as gene-environmental interplay. Currently, a follow-up study (CoTaSS 2) of the same cohort is underway, looking at the prevalence and interrelationship of key cardiovascular and metabolic risk markers (e.g., metabolic syndrome). A significant feature of CoTaSS 2 is the establishment of a biobank. Current SLTR work is extending beyond mental health and the interface between mental and physical health to new horizons, extending collaborations with the wider global twin research community. Ethics and governance have been given special emphasis in the initiative. Capacity building and public engagement are two crucial components. Establishment of a state-of-the-art genetic laboratory was a major accomplishment. SLTR is a classic showcase of successful North-South partnership in building a progressive research infrastructure in a LMIC. PMID:23302519

Sumathipala, Athula; Siribaddana, Sisira; Hotopf, Mathew; McGuffin, Peter; Glozier, Nick; Ball, Harriet; Kovas, Yulia; Rijsdijk, Fruhling; Yatawara, Lalani; Pariante, Carmine; Zavos, Helena; Siriwardhana, Chesmal; Pannala, Gayani; Jayaweera, Kaushalya; Adikari, Anushka; Gunewardane, Dinesha

2013-02-01

287

Monoamniotic Monochorionic Twins Discordant for Noncompaction Cardiomyopathy  

PubMed Central

Occasionally “identical twins” are phenotypically different, raising the question of zygosity and the issue of genetic versus environmental influences during development. We recently noted monochorionic-monoamniotic twins, one of which had an isolated cardiac abnormality, noncompaction cardiomyopathy, a condition characterized by cardiac ventricular hypertrabeculation. We examined the prenatal course and subsequent pathologic correlation since ventricular morphogenesis may depend on early muscular contraction and blood flow. The monochorionic-monoamniotic female twin pair was initially identified since one fetus presented with increased nuchal translucency. Complete heart block was later identified in the fetus with nuchal translucency who did not survive after delivery. In contrast, the unaffected twin had normal cardiac studies both prenatally and postnatally. Pathologic analysis of the affected twin demonstrated noncompaction of the left ventricle with dysplasia of the aortic and pulmonary valves. Dissection of the cardiac conduction system disclosed atrioventricular bundle fibrosis. Maternal lupus studies, amniocentesis with karyotype, and studies for 22q11.2 were normal. To test for zygosity, we performed multiple STR marker analysis and found that all markers were shared even using non-blood tissues from the affected twin. These studies demonstrate that monozygotic twins that are monochorionic monoamniotic can be discordant for cardiac noncompaction. The results suggest further investigation into the potential roles of pathologic fibrosis, contractility, and blood flow in cardiac ventricle development. PMID:23636980

Ng, Dianna; Bouhlal, Yosr; Ursell, Philip C.; Shieh, Joseph T.C.

2013-01-01

288

Indisputable double paternity in dizygous twins  

E-print Network

Setting: University paternity laboratory. Patient(s): Father, mother, and a set of twins. Intervention(s): Blood typing conventional markers, as well as polymerase chain reaction loci and restriction fragment length polymorphism loci of DNA. Main Outcome Measure(s): Heteropaternal superfecundation was demonstrated after paternity investigation. Result(s): The probability of paternity for twin 1 was 99.9999998%, whereas that for twin 2 was excluded on the basis of the following tests: Fy, Pi, human leukocyte antigen (HLA)-DQAl, DlS80, D17S.5, HBGG, D5S110, D2S44, and DlOS28. Conclusion(s): Dizygous twins can have different biologic fathers, as demonstrated in this case. According to published data, the frequency of twins with different fathers is probably underestimated, at least in small selected populations such as those of paternity suits. (Fertil Steril @ 1997;67:1159-61. 0 1997 by American Society for Reproductive Medicine.) Key Words: Paternity, superfecundation, superfetation, DNA, twins Twins may originate from a single fertilized egg

Eloy Girela; M. D. Maria; D. Rodrigo; Jose A. Lorente; M. D. Miguel Lorente; J. Carlos Alvarez; M. S. Enrique Villanueva

289

134. FORKS DIVERSION, HIGH LINE AND LOW LINE CANALS, TWIN ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

134. FORKS DIVERSION, HIGH LINE AND LOW LINE CANALS, TWIN FALLS COUNTY, SOUTH OF HANSEN, IDAHO; VIEW OF LOW LINE AND POWER GATES, WEST VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

290

131. FORKS DIVERSION, HIGH LINE AND LOW LINE CANALS, TWIN ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

131. FORKS DIVERSION, HIGH LINE AND LOW LINE CANALS, TWIN FALLS COUNTY, SOUTH OF HANSEN, IDAHO; INLET SIDE OF LOW LINE CANAL, WEST VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

291

136. FORKS DIVERSION, HIGH LINE AND LOW LINE CANALS, TWIN ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

136. FORKS DIVERSION, HIGH LINE AND LOW LINE CANALS, TWIN FALLS COUNTY, SOUTH OF HANSEN, IDAHO; HIGH LINE GATES FROM THE CANAL SIDE. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

292

132. FORKS DIVERSION, HIGH LINE AND LOW LINE CANALS, TWIN ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

132. FORKS DIVERSION, HIGH LINE AND LOW LINE CANALS, TWIN FALLS COUNTY, SOUTH OF HANSEN, IDAHO; POWER GATES FOR HYDRO-ELECTRIC. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

293

133. FORKS DIVERSION, HIGH LINE AND LOW LINE CANALS, TWIN ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

133. FORKS DIVERSION, HIGH LINE AND LOW LINE CANALS, TWIN FALLS COUNTY, SOUTH OF HANSEN, IDAHO; VIEW OF OUTLET SIDE OF LOW LINE GATES. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

294

130. FORKS DIVERSION, HIGH LINE AND LOW LINE CANALS, TWIN ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

130. FORKS DIVERSION, HIGH LINE AND LOW LINE CANALS, TWIN FALLS COUNTY, SOUTH OF HANSEN, IDAHO; OUTLET SIDE OF THE HIGH LINE GATES, NORTH VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

295

197. Photocopy of drawing, Twin Falls, Canal Company, date unknown. ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

197. Photocopy of drawing, Twin Falls, Canal Company, date unknown. GATE STEMS AND LIFTING DEVICES, NO COUNTY; BLUEPRINT SKETCHES. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

296

156. Photocopy of written record (taken from Twin Falls Canal ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

156. Photocopy of written record (taken from Twin Falls Canal Company, Low Line Book #1, pp.2,3). LOW LINE CONTRACTORS AND BORROW RECORD. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

297

Radiologic findings of Patterson-Lowry rhizomelic dysplasia in two sisters.  

PubMed

We report two sisters who have a rare skeletal abnormality termed Patterson-Lowry rhizomelic dysplasia. The typical findings of these cases on bone survey are isolated shortening and proximal metaphyseal enlargement and cupping of the bilateral humeri. The elder sister also has coxa vara deformity and dysplastic proximal femoral epiphyses on both sides. The younger sister has normal hip joint bones bilaterally, but her proximal femoral epiphyses are smaller than normal. All other bones of the sisters are of normal size and configuration. Our patients are two siblings, and their parents are first degree relatives, suggesting autosomal-recessive (AR) inheritance. The present patients help us to understand the genetic relationships and skeletal variabilities of this rare entity. PMID:25037730

Damar, Ça?r?; Boyuna?a, Öznur; Derinkuyu, Betül Emine; Battalo?lu, Nergiz; Ezgü, Fatih Süheyl

2014-11-01

298

40 CFR 79.65 - In vivo sister chromatid exchange assay.  

Code of Federal Regulations, 2013 CFR

...two sister chromatids of a duplicating chromosome. The most commonly used assays employ...the two chromatid arms within a single chromosome. This exchange is visualized during...harvested, fixed, and stained and their chromosomes are scored for SCEs. (3)...

2013-07-01

299

40 CFR 79.65 - In vivo sister chromatid exchange assay.  

Code of Federal Regulations, 2012 CFR

...two sister chromatids of a duplicating chromosome. The most commonly used assays employ...the two chromatid arms within a single chromosome. This exchange is visualized during...harvested, fixed, and stained and their chromosomes are scored for SCEs. (3)...

2012-07-01

300

40 CFR 79.65 - In vivo sister chromatid exchange assay.  

Code of Federal Regulations, 2010 CFR

...two sister chromatids of a duplicating chromosome. The most commonly used assays employ...the two chromatid arms within a single chromosome. This exchange is visualized during...harvested, fixed, and stained and their chromosomes are scored for SCEs. (3)...

2010-07-01

301

40 CFR 79.65 - In vivo sister chromatid exchange assay.  

Code of Federal Regulations, 2011 CFR

...two sister chromatids of a duplicating chromosome. The most commonly used assays employ...the two chromatid arms within a single chromosome. This exchange is visualized during...harvested, fixed, and stained and their chromosomes are scored for SCEs. (3)...

2011-07-01

302

Sister Circles as a Culturally Relevant Intervention for Anxious African American Women.  

PubMed

Research on anxiety treatment with African American women reveals a need to develop interventions that address factors relevant to their lives. Such factors include feelings of isolation, multiple roles undertaken by Black women, and faith. A recurrent theme across treatment studies is the importance of having support from other Black women. Sister circles are support groups that build upon existing friendships, fictive kin networks, and the sense of community found among African Americans females. Sister circles appear to offer many of the components Black women desire in an anxiety intervention. In this article, we explore sister circles as an intervention for anxious African American women. Culturally-infused aspects from our sister circle work with middle-class African American women are presented. Further research is needed. PMID:22081747

Neal-Barnett, Angela; Stadulis, Robert; Murray, Marsheena; Payne, Margaret Ralston; Thomas, Anisha; Salley, Bernadette B

2011-09-01

303

Sister Circles as a Culturally Relevant Intervention for Anxious African American Women  

PubMed Central

Research on anxiety treatment with African American women reveals a need to develop interventions that address factors relevant to their lives. Such factors include feelings of isolation, multiple roles undertaken by Black women, and faith. A recurrent theme across treatment studies is the importance of having support from other Black women. Sister circles are support groups that build upon existing friendships, fictive kin networks, and the sense of community found among African Americans females. Sister circles appear to offer many of the components Black women desire in an anxiety intervention. In this article, we explore sister circles as an intervention for anxious African American women. Culturally-infused aspects from our sister circle work with middle-class African American women are presented. Further research is needed. PMID:22081747

Neal-Barnett, Angela; Stadulis, Robert; Murray, Marsheena; Payne, Margaret Ralston; Thomas, Anisha; Salley, Bernadette B.

2011-01-01

304

When Your Brother or Sister Has Cancer: A Guide for Teens  

Cancer.gov

Tips on what to say to your friends, how to deal with stress, and where to find support – as well as information about cancer and cancer treatments, for young people who have a brother or sister with cancer.

305

Catholic nursing sisters and brothers and racial justice in mid-20th-century America.  

PubMed

This historical article considers nursing's work for social justice in the 1960s civil rights movement through the lens of religious sisters and brothers who advocated for racial equality. The article examines Catholic nurses' work with African Americans in the mid-20th century that took place amid the prevailing social conditions of poverty and racial disempowerment, conditions that were linked to serious health consequences. Historical methodology is used within the framework of "bearing witness," a term often used in relation to the civil rights movement and one the sisters themselves employed. Two situations involving nurses in the mid-20th century are examined: the civil rights movement in Selma, Alabama, and the actions for racial justice in Chicago, Illinois. The thoughts and actions of Catholic sister and brother nurses in the mid-20th century are chronicled, including those few sister nurses who stepped outside their ordinary roles in an attempt to change an unjust system entirely. PMID:19461224

Wall, Barbra Mann

2009-01-01

306

Psychopathology, childhood trauma, and personality traits in patients with borderline personality disorder and their sisters.  

PubMed

The aim of this study was to document and compare adverse childhood experiences, and personality profiles in women with borderline personality disorder (BPD) and their sisters, and to determine how these factors impact current psychopathology. Fifty-six patients with BPD and their sisters were compared on measures assessing psychopathology, personality traits, and childhood adversities. Most sisters showed little evidence of psychopathology. Both groups reported dysfunctional parent-child relationships and a high prevalence of childhood trauma. Subjects with BPD reported experiencing more emotional abuse and intrafamilial sexual abuse, but more similarities than differences between probands and sisters were found. In multilevel analyses, personality traits of affective instability and impulsivity predicted DIB-R scores and SCL-90-R scores, above and beyond trauma. There were few relationships between childhood adversities and other measures of psychopathology. Sensitivity to adverse experiences, as reflected in the development of psychopathology, appears to be influenced by personality trait profiles. PMID:21838561

Laporte, Lise; Paris, Joel; Guttman, Herta; Russell, Jennifer

2011-08-01

307

Shady Ladies: Sister Acts, Popular Performance, and the Subversion of American Identity  

E-print Network

"Shady Ladies: Sister Acts, Popular Performance, and the Subversion of American Identity" is a project with two major components. First, it is a historical project based on original archival research conducted at the ...

Buckner, Jocelyn Louise

2010-04-27

308

Teaching about twins: college courses and public lectures.  

PubMed

The present article describes teaching experiences and observations in college courses and public lectures on twins. It is concluded that much more information about twins, at both research and practical levels, requires general dissemination. This discussion is followed by reviews of recent twin research on the topics of obesity control, post-zygotic mutation, in vitro fertilization, and schisis-associated defects. Media reports of twins accused of rape, infant Chinese twins sold separately for profit, a twin CEO, and twins pursuing the same career are presented. PMID:24229489

Segal, Nancy L

2013-12-01

309

Cohesin gene defects may impair sister chromatid alignment and genome stability in Arabidopsis thaliana  

Microsoft Academic Search

In contrast to yeast, plant interphase nuclei often display incomplete alignment (cohesion) along sister chromatid arms. Sister\\u000a chromatid cohesion mediated by the multi-subunit cohesin complex is essential for correct chromosome segregation during nuclear\\u000a divisions and for DNA recombination repair. The cohesin complex consists of the conserved proteins SMC1, SMC3, SCC3, and an\\u000a ?-kleisin subunit. Viable homozygous mutants could be selected

Veit Schubert; Andrea Weißleder; Hoda Ali; Jörg Fuchs; Inna Lermontova; Armin Meister; Ingo Schubert

2009-01-01

310

The Boston University Twin Project (BUTP)  

PubMed Central

The Boston University Twin Project (BUTP) is a multimetthod, multi-situation, longitudinal study of early child temperament and related behaviors. The first phase of this project focused on primarily on activity level and comprised over 300 twin pairs assessed in the home and lab at ages 2 and 3. Subject recruitment, sample characteristics and study procedures are described. A second phase broadens our focus to the development of multiple temperament dimensions and developmental outcomes in a new cohort of 300 twin pairs to be assessed at 3, 4 and 5 years of age. Recruitment is currently underway. PMID:23046533

Saudino, Kimberly J; Asherson, Philip

2013-01-01

311

On Radar Time and the Twin `Paradox'  

E-print Network

In this paper we apply the concept of radar time (popularised by Bondi in his work on k-calculus) to the well-known relativistic twin `paradox'. Radar time is used to define hypersurfaces of simultaneity for a class of travelling twins, from the `Immediate Turn-around' case, through the `Gradual Turn-around' case, to the `Uniformly Accelerating' case. We show that this definition of simultaneity is independent of choice of coordinates, and assigns a unique time to any event (with which the travelling twin can send and receive signals), resolving some common misconceptions.

Carl E. Dolby; Stephen F. Gull

2001-04-24

312

Venus, Earth's structural sister: Investigations using radar imagery  

NSDL National Science Digital Library

Students construct a geologic map of a region of Venus' surface using NASA Magellan synthetic aperture radar(SAR) data (provided) and/or synthetic stereo data (provided, and constructed using Magellan SAR and altimetry data)- 3D anaglyph viewed through red-blue glasses. Mapping can be done digitally using Adobe Illustrator (or a similar graphic program) or using hard copy images and overhead transparencies for mapping. Students construct a complete geologic map, determine a geologic history for the area, and propose hypotheses for the evolution of a large quasi-circular geomorphic/geologic feature that occurs within the map area. Students also propose tests of their hypotheses (whether such tests can be accomplished through further mapping, future missions, experiments, theoretical arguments, calculations, etc.). Students must clearly identify assumptions they make in their hypotheses/models. Individual, or small group, write-ups and completed geologic maps summarize student analysis. This activity connects structural geology to other fields, and provides the students with an opportunity to experience geologic investigation in which there is no single right answer, but there are "wrong" or unlikely hypotheses. This exercise helps students think outside the box with little fear given that they are dealing with - literally - an extraterrestrial world in which very little is known - and yet, we assume that chemistry and physics, as we know them, likely operated on Earth's sister planet. Students are given a short introductory presentation about the environmental conditions of Venus (which could have been different in the past), and an introduction to radar data before they begin.

Hansen, Vicki

313

The second twin: inter-twin delivery time, umbilical arterial PH and apgar scores  

Microsoft Academic Search

Background and aimsAdverse outcomes have been associated with a prolonged inter-twin delivery time. The aim of the present study was to analyse the effects of inter-twin delivery time on umbilical artery pH and Apgar scores with a view to establish a time at which there is an increased risk of fetal acidosis.MethodA retrospective study of twin births delivered at Jessops

S R Stenton; D O C Anumba

2011-01-01

314

Postnatal respiratory distress in a dichorial twin with congenital thoracic neuroblastoma after assisted reproduction by intracytoplasmatic sperm injection.  

PubMed

We report on the case of a female twin with congenital thoracic neuroblastoma after conception via intracytoplasmatic sperm injection (ICSI). Birth occurred at 37 + 1-week gestation per primary sectio caesarea. Acute respiratory distress necessitated intubation and mechanical ventilation. Ultrasound and magnetic resonance imaging (MRI) showed a mass in the right upper thorax compressing the trachea. The tumor was subtotally excised and histological analysis revealed neuroblastoma. No further treatment was given. The residual primary tumor regressed spontaneously. Four years after diagnosis, both twins are healthy and normally developed. PMID:16807915

Langer, Thorsten; Deeg, Karl-Heinz; Hümmer, Peter; Paulides, Marios; Beck, Jörn-Dirk; Klinge, Jens

2007-03-01

315

Meconium peritonitis in both fetuses with early twin-to-twin transfusion syndrome.  

PubMed

Twin-to-twin transfusion syndrome (TTTS) is due to unbalanced inter-twin bloodflow through placental vascular anastomoses. We present a TTTS case treated with fetoscopic laser photocoagulation (FLP) that was complicated by perinatal meconium peritonitis in both twins. Ten weeks following laser treatment, the two fetuses showed intra-abdominal hyperechogenicity and ascites. After birth, the two newborns were surgically managed for peritonitis. We discuss the pathogenesis of this double insult. The present case highlights the role of end-circulation bowel thrombi as the potential cause of subsequent intestinal perforation. PMID:22853881

Marcellin, Louis; Quintana, Andrea; Essaoui, Mohamed; Anselem, Olivia; Beaudoin, Sylvie; El Ayoubi, Mayas; Boujenah, Laurence; Salhi, Houria; Tsatsaris, Vassili

2012-08-01

316

Twin–twin transfusion syndrome: cerebral ischemia is not the only fetal MR imaging finding  

Microsoft Academic Search

Background  Twin–twin transfusion syndrome (TTTS) is a complication of monochorionic\\/diamniotic twin pregnancies. An imbalance of blood\\u000a flow occurs through placental anastomoses, causing potentially significant morbidity and mortality in both twins. Although\\u000a the sonographic findings of TTTS are well documented, we believe that MR imaging is a valuable adjunct.\\u000a \\u000a \\u000a \\u000a Objective  We describe the fetal MR imaging findings associated with TTTS.\\u000a \\u000a \\u000a \\u000a Materials and methods  From

Beth M. Kline-Fath; Maria A. Calvo-Garcia; Sara M. O’Hara; Timothy M. Crombleholme; Judy M. Racadio

2007-01-01

317

Comparison of Naturally Conceived and IVF-DZ Twins in the Netherlands Twin Registry: A Developmental Study  

PubMed Central

In a large set of twin pairs, we compared twins born after IVF to naturally conceived twins with respect to birth characteristics, growth, attainment of motor milestones, and emotional and behavioral problems. Twin families were registered with the Netherlands Twin Register. We included 1534 dizygotic (DZ) twins born after IVF, 5315 naturally conceived (NC) DZ twins, and 1504 control NC DZ twins who were matched to the IVF twins based on maternal age, maternal educational level, smoking during pregnancy, gestational age, and offspring sex. Data were obtained by longitudinal surveys sent to fathers, mothers, and teachers at ages 1, 2, 3, 7, 10, and 12 years. Results showed no differences in growth, in attainment of motor milestones, and in behavioral development between IVF and matched NC twins. It can be concluded that for nearly all aspects, development in IVF and NC children is similar. PMID:22132337

van Beijsterveldt, Catharina E. M.; Bartels, Meike; Boomsma, Dorret I.

2011-01-01

318

Shock Driven Twinning in Tantalum Single Crystals  

SciTech Connect

Recovery based observations of high pressure material behavior generated under high explosively driven flyer based loading conditions are reported. Two shock pressures, 25, and 55 GPa and four orientations {l_brace}(100), (110), (111), (123){r_brace} were considered. Recovered material was characterized using electron backscatter diffraction along with a limited amount of transmission electron microscopy to assess the occurrence of twinning under each test condition. Material recovered from 25 GPa had a very small fraction of twinning for the (100), (110), and (111) oriented crystals while a more noticeable fraction of the (123) oriented crystal was twinned. Material recovered from 55 GPa showed little twinning for (100) orientation slightly more for the (111) orientation and a large area fraction for the (123) orientation. The EBSD and TEM observations of the underlying deformation substructure are rationalized by comparing with previous static and dynamic results.

McNaney, J M; HSUING, L M; Barton, N R; Kumar, M

2009-07-20

319

Coupling of twin rectangular supersonic jets  

E-print Network

Twin jet plumes on aircraft can couple, producing dynamic pressures significant enough to cause structural fatigue. For closely spaced jets with a moderate aspect ratio (e.g. 5), previous work has established that two coupling modes (antisymmetric...

Raman, G.; Taghavi, Ray

1998-01-01

320

The South Korean Twin Registry: an update.  

PubMed

The South Korean Twin Registry (SKTR) is an ongoing nation-wide volunteer registry of South Korean twins and their families, which was established in the year 2001 to understand genetic and environmental etiologies of psychological and physical traits among South Koreans. Recently, the SKTR sampling has been extended in two important ways. First, we began to recruit twins from lower socio-economic families to study interaction effects of gene by environmental context. Second, as a parallel study of the SKTR, the Nigerian Twin and Sibling Registry was developed to understand the origin of the population group differences/similarities in psychological traits between South Koreans and Nigerians. This article summarizes the main findings (based on the SKTR sample to date), recruitment procedures, zygosity assessment, measures, and future plans for the SKTR. PMID:23194648

Hur, Yoon-Mi; Jeong, Hoe-Uk; Chung, Kee Wha; Shin, Joong Sik; Song, Tae-Bok

2013-02-01

321

Monozygotic twins concordant for autism and hyperlexia.  

PubMed

The authors describe male monozygotic twins, Jon and Jay, who are concordant for autism and hyperlexia. Autism and mental retardation were diagnosed at the age of 2 years 5 months. Jay was the more advanced twin in motor co-ordination, attention span and receptive abilities, but had frequent tantrums. When psychologically assessed at 7 years 2 months, Jon showed borderline/severe mental retardation on the measure of non-verbal intelligence and Jay was moderately retarded. Their receptive language age was greater than their expressive language age: Jon's speech was less mature but more communicative and Jay's was perseverative and ritualistic. Even though Jon was the more mentally retarded twin, Jay was the more autistic in some behavioral aspects. These twins highlight the relationship between autism and hyperlexia. PMID:3169393

Smith, I M; Bryson, S E

1988-08-01

322

Severe Anisometropic Myopia in Identical Twins  

PubMed Central

High anisometropic myopia is a rare condition in twins. Genetic factors have been implicated in its development and there may be an association with vision-threatening complications. A pair of 11-year-old twins presented with poor distance vision in both eyes. Detailed ocular examination was performed including slit lamp examination, dilated funduscopy, cycloplegic refraction, keratometry and axial length measurement. The objective refraction was -6.50DS -2.00DC × 180 (right eye), -1.00DS (left eye) for the first twin; -13.75DS -2.25DC × 180 (right eye), -0.50DS -0.75DC × 04 (left eye) for the second twin. This case suggests an underlying genetic defect in the development of myopia. PMID:25100917

Adenuga, Olukorede O.

2014-01-01

323

Nanoscale Growth Twins in Sputtered Copper Films  

E-print Network

copper films are synthesized on HF etched Si (110) substrates. These films show high hardness (~ 2.8 GPa) due to high density of coherent twin boundaries (CTBs) which effectively block the motion of dislocations similar to grain boundaries (GBs...

Anderoglu, Osman

2011-08-08

324

Indisputable double paternity in dizygous twins  

Microsoft Academic Search

Objective: To report a case of heteropaternal superfecundation.Design: Case report.Setting: University paternity laboratory.Patient(s): Father, mother, and a set of twins.Intervention(s): Blood typing conventional markers, as well as polymerase chain reaction loci and restriction fragment length polymorphism loci of DNA.Main Outcome Measure(s): Heteropaternal superfecundation was demonstrated after paternity investigation.Result(s): The probability of paternity for twin 1 was 99.9999998%, whereas that for

Eloy Girela; Jose A. Lorente; J. Carlos Alvarez; Maria D. Rodrigo; Miguel Lorente; Enrique Villanueva

1997-01-01

325

Imperfect twinning: a clinical and ethical dilemma  

PubMed Central

OBJECTIVE To review the history, epidemiology, etiology, gestational aspects, diagnosis and prognosis of imperfect twinning. DATA SOURCES Scientific articles were searched in PubMed, SciELO and Lilacs databases, using the descriptors "conjoined twins", "multiple pregnancy", "ultrasound", "magnetic resonance imaging" and "prognosis". The research was not delimited to a specific period of time and was supplemented with bibliographic data from books. DATA SYNTHESIS: The description of conjoined twins is legendary. The estimated frequency is 1/45,000-200,000 births. These twins are monozygotic, monochorionic and usually monoamniotic. They can be classified by the most prominent fusion site, by the symmetry between the conjoined twins or by the sharing structure. The diagnosis can be performed in the prenatal period or after birth by different techniques, such as ultrasound, magnetic resonance imaging and echocardiography. These tests are of paramount importance for understanding the anatomy of both fetuses/children, as well as for prognosis and surgical plan determination. CONCLUSIONS Although imperfect twinning is a rare condition, the prenatal diagnosis is very important in order to evaluate the fusion site and its complexity. Hence, the evaluation of these children should be multidisciplinary, involving mainly obstetricians, pediatricians and pediatric surgeons. However, some decisions may constitute real ethical dilemmas, in which different points should be discussed and analyzed with the health team and the family. PMID:24142323

Denardin, Daniela; Telles, Jorge Alberto B.; Betat, Rosilene da Silveira; Fell, Paulo Renato K.; da Cunha, Andre Campos; Targa, Luciano Vieira; Zen, Paulo Ricardo G.; Rosa, Rafael Fabiano M.

2013-01-01

326

Silicic Eruptions of the Past 50 kyr at the Three Sisters Volcanic Cluster  

NASA Astrophysics Data System (ADS)

The Three Sisters volcanic cluster in the central Oregon Cascades consists of mafic to intermediate stratovolcanoes surrounded by mafic and silicic flows and domes. The bulk of South and Middle Sister are late Pleistocene while North Sister is middle Pleistocene (Schmidt and Grunder, 2003 GSA abs.). Thick rhyolite and dacite lava flows and domes are rich in potassium, and young glaciation exposes holocrystalline groundmass textures ideal for argon geochronology. Several of these silicic flows bracket stratovolcano growth, and precise geochronology illuminates a rich basalt to rhyolite history in the cluster over the past 50 kyr. Careful step-heating 40Ar/39Ar experiments yield excellent plateau ages with radiogenic yields often above 5% on rocks as young as 20 ka. Most samples have well-determined isochrons with atmospheric (40/36 = 295.5) intercepts, although several have intercepts as low as 286. South Sister is a composite cone with an andesite/dacite base (Hodge Crest) and a young andesite summit sequence. The basal flow of the 300m-thick, youngest conformable stack of andesite lavas at the summit is 27+/-3 ka. Unconformably underlying portions date back to at least 50 ka based on ages of overlapping silicic flows. The base of Middle Sister is andesite overlain by ˜300m of olivine basalt. Some Middle Sister andesites and all basalts overlie a distinctive dacite agglutinate (20+/-2 ka) in the South/Middle Sister saddle. All Middle Sister lavas underlie a thick dacite flow (14+/-3 ka) that vented at 8500 ft (2600m) on its S flank. Dacite lava flows erupted from the Middle/North Sister saddle at 27+/-2 and 18+/-2 ka. Additionally, several >100m-thick rhyolite and dacite lavas vented low on the flanks of the cluster. Obsidian Cliff rhyolite (37.8+/-1.8 ka) and Lane Plateau dacite (21.4+/-1.9 ka) erupted W of Middle Sister, the Dew Lake dacite (32.3+/-1.8 ka) located near the locus of the INSAR anomaly W of South Sister flowed around a 148+/-4 ka (knob 6482) basalt and near the 149+/-5 ka (The Husband), 159+/-10 ka (Upper Mesa Creek) and 279+/-6 ka (The Sphinx) basalts. The south flank of South Sister is dominated by the late Holocene rhyolites of Rock Mesa and the Devil's Hill chain and about ten 24-50 ka rhyolite and dacite domes and flows. A 100m-thick 35+/-2 ka rhyolite lava also extends NE from South Sister into Squaw Creek. In sum, South and Middle Sisters are mafic to intermediate and their youngest activity is coeval. Silicic flows on and around the volcanic cluster are voluminous, abundant and young.

Calvert, A. T.; Hildreth, W.; Fierstein, J.

2003-12-01

327

Development of the Preterm Gut Microbiome in Twins at Risk of Necrotising Enterocolitis and Sepsis  

PubMed Central

The preterm gut microbiome is a complex dynamic community influenced by genetic and environmental factors and is implicated in the pathogenesis of necrotising enterocolitis (NEC) and sepsis. We aimed to explore the longitudinal development of the gut microbiome in preterm twins to determine how shared environmental and genetic factors may influence temporal changes and compared this to the expressed breast milk (EBM) microbiome. Stool samples (n = 173) from 27 infants (12 twin pairs and 1 triplet set) and EBM (n = 18) from 4 mothers were collected longitudinally. All samples underwent PCR-DGGE (denaturing gradient gel electrophoresis) analysis and a selected subset underwent 454 pyrosequencing. Stool and EBM shared a core microbiome dominated by Enterobacteriaceae, Enterococcaceae, and Staphylococcaceae. The gut microbiome showed greater similarity between siblings compared to unrelated individuals. Pyrosequencing revealed a reduction in diversity and increasing dominance of Escherichia sp. preceding NEC that was not observed in the healthy twin. Antibiotic treatment had a substantial effect on the gut microbiome, reducing Escherichia sp. and increasing other Enterobacteriaceae. This study demonstrates related preterm twins share similar gut microbiome development, even within the complex environment of neonatal intensive care. This is likely a result of shared genetic and immunomodulatory factors as well as exposure to the same maternal microbiome during birth, skin contact and exposure to EBM. Environmental factors including antibiotic exposure and feeding are additional significant determinants of community structure, regardless of host genetics. PMID:24023682

Stewart, Christopher J.; Marrs, Emma C. L.; Nelson, Andrew; Lanyon, Clare; Perry, John D.; Embleton, Nicholas D.; Cummings, Stephen P.; Berrington, Janet E.

2013-01-01

328

Plagioclase twin laws in lunar highland rocks - Possible petrogenetic significance  

NASA Technical Reports Server (NTRS)

Plagioclases in different types of lunar highland rocks (all highly feldspathic) are twinned according to different laws and in different styles. Carlsbad and Carlsbad-albite twins, presumed to be growth twins, occur mainly in rocks which show igneous texture, and which have not been severely brecciated. These two twin laws appear to be absent from cataclastic rocks, including cataclastic anorthosite, possibly because the original twins were preferentially broken up in cataclasis (the composition plane being a plane of weakness). Pericline and lamellar albite twins, presumed to be deformation twins (except for some albite growth twins) occur in all types of rocks, and obvious deformation features, such as bending of lamellae, are well shown in many cataclastic rocks. Surprisingly, some Carlsbad and Carlsbad-albite twins are found in rocks with granoblastic texture, which presumably recrystallized in the solid state.

Dowty, E.; Keil, K.; Prinz, M.

1974-01-01

329

Normal personality characteristics in identical twins discordant for schizophrenia.  

PubMed

The authors examined normal personality characteristics of monozygotic (MZ) twins discordant for schizophrenia. Twenty pairs of discordant twins were analyzed; 11 pairs of MZ twins concordant for schizophrenia served as a comparison group. Personality was assessed using the Multidimensional Personality Questionnaire (MPQ; A. Tellegen, 1995). Among discordant twin pairs, twins with schizophrenia were more deviant than normal co-twins on all but 4 of the MPQ's scales. Analysis of MZ twin correlations among the discordant twin pairs revealed substantial erosion of personality similarity as compared to normal individuals, although a cluster of scales related to Constraint/Psychoticism showed significant correlations. The results highlight striking personality divergence related to nonshared environmental influences. It is not possible to determine the point at which the twins diverged, although previous findings from this sample suggest that the observed personality differences may reflect effects of schizophrenia on normal personality. PMID:7673572

DiLalla, D L; Gottesman, I I

1995-08-01

330

Reversed Twin-to-Twin Transfusion Syndrome following Successful Laser Therapy  

Microsoft Academic Search

We report a case of severe twin-to-twin transfusion syndrome (TTTS) in which fetoscopic laser ablation was successfully performed at 21 weeks’ gestation. Despite successful resolution of signs on ultrasound examination after a period of 7 weeks, the donor developed polyhydramnios whereas the ‘initial’ recipient maintained normal liquor volume, features suggestive of ‘reversed TTTS’. Two live babies were delivered at 31

Caroline E. Fox; Ben C. Chan; Phillip Cox; Adam Gornall; Mark D. Kilby

2009-01-01

331

Langevin's `Twin Paradox' paper revisited  

E-print Network

An in-depth and mathematically-detailed analysis of Langevin's popular 1911 article on the special theory of relativity is presented. For the reader's convenience, English translations of large parts of the original French text are given. The self-contradictory nature of many of Langevin's assertions is pointed out. Of special interest is the analysis of the exchange of light signals between the travelling and stay-at-home twins in Langevin's thought experiment, in which antinomies are found in the conventional relativistic treatment. Their resolution shows that the physical basis of the differential aging effect in the experiment is not `length contraction', as in the conventional interpretation, but instead the application of the correct relative velocity transformation formula. The spurious nature of the correlated `length contraction' and `relativity of simultaneity' effects of conventional special relativity is also demonstrated. In consequence, an argument given, claiming to demonstrate that an upper limit of $c$ on the speed of any physical signal is required by causality, is invalid. Its conclusion is also in contradiction with astronomical observations and the results of a recent experiment.

J. H. Field

2008-11-21

332

Aeroacoustic Experiments with Twin Jets  

NASA Technical Reports Server (NTRS)

While the noise produced by a single jet is azimuthally symmetric, multiple jets produce azimuthally varying far-field noise. The ability of one jet to shield another reduces the noise radiated in the plane of the jets, while often increasing the noise radiated out of the plane containing the jets. The present study investigates the shielding potential of twin jet configurations over subsonic and over-expanded supersonic jet conditions with simulated forward flight. The experiments were conducted with 2 in. throat diameter nozzles at four jet spacings from 2.6d to 5.5d in center-to-center distance, where d is the nozzle throat diameter. The current study found a maximum of 3 dB reduction in overall sound pressure level relative to two incoherent jets in the peak jet noise direction in the plane containing the jets. However, an increase of 3 dB was found perpendicular to the plane containing the jets. In the sideline direction, shielding is observed for all jet spacings in this study.

Bozak, Richard F.; Henderson, Brenda S.

2012-01-01

333

Digital Data for Volcano Hazards of the Three Sisters Region, Oregon  

USGS Publications Warehouse

Three Sisters is one of three active volcanic centers that lie close to rapidly growing communities and resort areas in Central Oregon. The major composite volcanoes of this area are clustered near the center of the region and include South Sister, Middle Sister, and Broken Top. Additionally, hundreds of mafic volcanoes are scattered throughout the Three Sisters area. These range from small cinder cones to large shield volcanoes like North Sister and Belknap Crater. Hazardous events include landslides from the steep flanks of large volcanoes and floods, which need not be triggered by eruptions, as well as eruption-triggered events such as fallout of tephra (volcanic ash) and lava flows. A proximal hazard zone roughly 20 kilometers (12 miles) in diameter surrounding the Three Sisters and Broken Top could be affected within minutes of the onset of an eruption or large landslide. Distal hazard zones that follow river valleys downstream from the Three Sisters and Broken Top could be inundated by lahars (rapid flows of water-laden rock and mud) generated either by melting of snow and ice during eruptions or by large landslides. Slow-moving lava flows could issue from new mafic volcanoes almost anywhere within the region. Fallout of tephra from eruption clouds can affect areas hundreds of kilometers (miles) downwind, so eruptions at volcanoes elsewhere in the Cascade Range also contribute to volcano hazards in Central Oregon. Scientists at the Cascades Volcano Observatory created a geographic information system (GIS) data set which depicts proximal and distal lahar hazard zones as well as a regional lava flow hazard zone for Three Sisters (USGS Open-File Report 99-437, Scott and others, 1999). The various distal lahar zones were constructed from LaharZ software using 20, 100, and 500 million cubic meter input flow volumes. Additionally, scientists used the depositional history of past events in the Three Sisters Region as well as experience and judgment derived from the study of volcanoes to help construct the regional hazard zone.

Schilling, S. P.; Doelger, S.; Scott, W. E.; Iverson, R. M.

2008-01-01

334

Deformation twinning mechanisms in FCC and HCP metals  

SciTech Connect

We report the recent work on twinning and detwinning in fcc and hcp metals based on the in situ and ex situ TEM observations and molecular dynamics simulations. Three aspects are discussed in this paper. (1) Detwinning in single-phase Cu with respect to growth twins, (2) deformation twinning in Ag-Cu composites, and (3) deformation twinning mechanisms in hcp metals. The main conclusion is that atomic structures of interfaces (twin boundaries, two-phases interface, and grain boundaries) play a crucial role in nucleating and propagating of deformation twins.

Wang, Jian [Los Alamos National Laboratory; Tome, Carlos N [Los Alamos National Laboratory; Beyerlein, Irene J [Los Alamos National Laboratory; Misra, Amit [Los Alamos National Laboratory; Mara, N [Los Alamos National Laboratory

2011-01-31

335

Sisters Unbound Is Required for Meiotic Centromeric Cohesion in Drosophila melanogaster.  

PubMed

Regular meiotic chromosome segregation requires sister centromeres to mono-orient (orient to the same pole) during the first meiotic division (meiosis I) when homologous chromosomes segregate, and to bi-orient (orient to opposite poles) during the second meiotic division (meiosis II) when sister chromatids segregate. Both orientation patterns require cohesion between sister centromeres, which is established during meiotic DNA replication and persists until anaphase of meiosis II. Meiotic cohesion is mediated by a conserved four-protein complex called cohesin that includes two structural maintenance of chromosomes (SMC) subunits (SMC1 and SMC3) and two non-SMC subunits. In Drosophila melanogaster, however, the meiotic cohesion apparatus has not been fully characterized and the non-SMC subunits have not been identified. We have identified a novel Drosophila gene called sisters unbound (sunn), which is required for stable sister chromatid cohesion throughout meiosis. sunn mutations disrupt centromere cohesion during prophase I and cause high frequencies of non-disjunction (NDJ) at both meiotic divisions in both sexes. SUNN co-localizes at centromeres with the cohesion proteins SMC1 and SOLO in both sexes and is necessary for the recruitment of both proteins to centromeres. Although SUNN lacks sequence homology to cohesins, bioinformatic analysis indicates that SUNN may be a structural homolog of the non-SMC cohesin subunit stromalin (SA), suggesting that SUNN may serve as a meiosis-specific cohesin subunit. In conclusion, our data show that SUNN is an essential meiosis-specific Drosophila cohesion protein. PMID:25194162

Krishnan, Badri; Thomas, Sharon E; Yan, Rihui; Yamada, Hirotsugu; Zhulin, Igor B; McKee, Bruce D

2014-11-01

336

Drosophila Separase is required for sister chromatid separation and binds to PIM and THR  

PubMed Central

Drosophila PIM and THR are required for sister chromatid separation in mitosis and associate in vivo. Neither of these two proteins shares significant sequence similarity with known proteins. However, PIM has functional similarities with securin proteins. Like securin, PIM is degraded at the metaphase-to-anaphase transition and this degradation is required for sister chromatid separation. Securin binds and inhibits separase, a conserved cysteine endoprotease. Proteolysis of securin at the metaphase-to-anaphase transition activates separase, which degrades a conserved cohesin subunit, thereby allowing sister chromatid separation. To address whether PIM regulates separase activity or functions with THR in a distinct pathway, we have characterized a Drosophila separase homolog (SSE). SSE is an unusual member of the separase family. SSE is only about one-third the size of other separases and has a diverged endoprotease domain. However, our genetic analyses show that SSE is essential and required for sister chromatid separation during mitosis. Moreover, we show that SSE associates with both PIM and THR. Although our work shows that separase is required for sister chromatid separation in higher eukaryotes, in addition, it also indicates that the regulatory proteins have diverged to a surprising degree, particularly in Drosophila. PMID:11581162

Jager, Hubert; Herzig, Alf; Lehner, Christian F.; Heidmann, Stefan

2001-01-01

337

Mechanics of Sister Chromatids studied with a Polymer Model English</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p class="result-summary"><span class="hlt">Sister</span> chromatid cohesion denotes the phenomenon that <span class="hlt">sister</span> chromatids are initially attached to each other in mitosis to guarantee the error-free distribution into the daughter cells. Cohesion is mediated by binding proteins and only resolved after mitotic chromosome condensation is completed. However, the amount of attachement points required to maintain <span class="hlt">sister</span> chromatid cohesion while still allowing proper chromosome condensation is not known yet. Additionally the impact of cohesion on the mechanical properties of chromosomes also poses an interesting problem. In this work we study the conformational and mechanical properties of <span class="hlt">sister</span> chromatids by means of computer simulations. We model both protein-mediated cohesion between <span class="hlt">sister</span> chromatids and chromosome condensation with a dynamic binding mechanisms. We show in a phase diagram that only specific link concentrations lead to connected and fully condensed chromatids that do not intermingle with each other nor separate due to entropic forces. Furthermore we show that dynamic bonding between chromatids decrease the Young's modulus compared to non-bonded chromatids.</p> <div class="credits"> <p class="dwt_author">Zhang, Yang; Isbaner, Sebastian; Heermann, Dieter</p> <p class="dwt_publisher"></p> <p class="publishDate">2013-10-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">338</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.osti.gov/scitech/biblio/478890"> <span id="translatedtitle">Neuropsychological profiles of three <span class="hlt">sisters</span> homozygous for the fragile X premutation</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p class="result-summary">Fragile X syndrome (fraX) is associated with an amplification of a CGG repeat within the fraX mental retardation (FMR-1) gene. We describe an exceptional family in which 3 adult <span class="hlt">sisters</span> are homozygous for the FMR-1 premutation. Each <span class="hlt">sister</span> inherited 2 premutation alleles (ca. 80 CGG repeats) from their biologically unrelated parents. The 3 <span class="hlt">sisters</span> were administered measures of executive function, visual spatial, memory, and verbal skills. Deficiencies in the first 2 of these domains have been reported among females with the full mutation. The <span class="hlt">sisters</span>` performances were compared with available normative data and with published group means for females affected by fraX. These women did not appear to have verbal or memory difficulties. None of the women demonstrated a global executive function deficit, and none had global deficits in spatial ability. The profiles of these <span class="hlt">sisters</span> are consistent with reports that the fragile X premutation does not affect cognitive performance. 31 refs., 1 fig., 4 tabs.</p> <div class="credits"> <p class="dwt_author">Mazzocco, M.M.M. [Johns Hopkins School of Medicine, Baltimore, MD (United States)] [Johns Hopkins School of Medicine, Baltimore, MD (United States); Holden, J.J.A. [Ongwanada Resource Centre, Kingston, Ontario (Canada)] [Ongwanada Resource Centre, Kingston, Ontario (Canada)</p> <p class="dwt_publisher"></p> <p class="publishDate">1996-08-09</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">339</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4110534"> <span id="translatedtitle">Two <span class="hlt">sisters</span> reveal autosomal recessive inheritance of epidermodysplasia verruciformis: a case report</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p class="result-summary">Background Epidermodysplasia verruciformis is a rare genodermatosis characterized by a unique susceptibility to cutaneous human papillomaviruses infection. Most patients show autosomal recessive patterns of inheritance. Case presentation We report a case of two <span class="hlt">sisters</span> with clinically epidermodysplasia verruciformis specific lesions on the face, neck, trunk, and extremities. PCR analysis indicated the presence of human papillomavirus type 5 in the lesions. Electron microscopic examination showed viral-like particles in keratinocyte nuclei and the stratum corneum of the epidermodysplasia verruciformis lesions. In addition, we examined the EVER1 and EVER2 genes using eight different primer pairs without finding any nonsense or frameshift mutations in the gDNA from lymphocytes of the elder <span class="hlt">sister</span>. Conclusions In this report, the patient’s parents did not have epidermodysplasia verruciformis lesions or a consanguineous marriage. EV did not develop in the elder <span class="hlt">sister</span> until five years of age, so the parents did not perceive EV as an inherited disease. The probability that EV developed in both <span class="hlt">sisters</span> was only 6.25%. Thus, it is rare for both <span class="hlt">sisters</span> to develop epidermodysplasia verruciformis lesions considering that the parents were presumed to be carriers and the disease reveal an autosomal recessive pattern of inheritance. PMID:25048734</p> <div class="credits"> <p class="dwt_author"></p> <p class="dwt_publisher"></p> <p class="publishDate">2014-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">340</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.ncbi.nlm.nih.gov/pubmed/23394192"> <span id="translatedtitle">Two cohort and three independent anonymous <span class="hlt">twin</span> projects at the Keio <span class="hlt">Twin</span> Research Center (KoTReC).</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p class="result-summary">The Keio <span class="hlt">Twin</span> Research Center has conducted two longitudinal <span class="hlt">twin</span> cohort projects and has collected three independent and anonymous <span class="hlt">twin</span> data sets for studies of phenotypes related to psychological, socio-economic, and mental health factors. The Keio <span class="hlt">Twin</span> Study has examined adolescent and adult cohorts, with a total of over 2,400 pairs of <span class="hlt">twins</span> and their parents. DNA samples are available for approximately 600 of these <span class="hlt">twin</span> pairs. The Tokyo <span class="hlt">Twin</span> Cohort Project has followed a total of 1,600 <span class="hlt">twin</span> pairs from infancy to early childhood. The large-scale cross-sectional <span class="hlt">twin</span> study (CROSS) has collected data from over 4,000 <span class="hlt">twin</span> pairs, from 3 to 26 years of age, and from two high school <span class="hlt">twin</span> cohorts containing a total of 1,000 pairs of <span class="hlt">twins</span>. These data sets of anonymous <span class="hlt">twin</span> studies have mainly targeted academic performance, attitude, and social environment. The present article introduces the research designs and major findings of our center, such as genetic structures of cognitive abilities, personality traits, and academic performances, developmental effects of genes and environment on attitude, socio-cognitive ability and parenting, genes x environment interaction on attitude and conduct problem, and statistical methodological challenges and so on. We discuss the challenges in conducting <span class="hlt">twin</span> research in Japan. PMID:23394192</p> <div class="credits"> <p class="dwt_author">Ando, Juko; Fujisawa, Keiko K; Shikishima, Chizuru; Hiraishi, Kai; Nozaki, Mari; Yamagata, Shinji; Takahashi, Yusuke; Ozaki, Koken; Suzuki, Kunitake; Deno, Minako; Sasaki, Shoko; Toda, Tatsushi; Kobayashi, Kazuhiro; Sugimoto, Yutaro; Okada, Mitsuhiro; Kijima, Nobuhiko; Ono, Yutaka; Yoshimura, Kimio; Kakihana, Shinichiro; Maekawa, Hiroko; Kamakura, Toshimitsu; Nonaka, Koichi; Kato, Noriko; Ooki, Syuichi</p> <p class="dwt_publisher"></p> <p class="publishDate">2013-02-01</p> </div> </div> </div> </div> <div id="filter_results_form" class="filter_results_form floatContainer" style="visibility: visible;"> <div style="width:100%" id="PaginatedNavigation" class="paginatedNavigationElement"> <a id="FirstPageLink" onclick='return showDiv("page_1");' href="#" title="First Page"> <img id="FirstPageLinkImage" class="Icon" src="http://www.science.gov/scigov/images/icon.first.18x20.png" alt="First Page" /></a> <a id="PreviousPageLink" 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href="#">3</a> <a onClick='return showDiv("page_4");' href="#">4</a> <a onClick='return showDiv("page_5");' href="#">5</a> <a onClick='return showDiv("page_6");' href="#">6</a> <a onClick='return showDiv("page_7");' href="#">7</a> <a onClick='return showDiv("page_8");' href="#">8</a> <a onClick='return showDiv("page_9");' href="#">9</a> <a onClick='return showDiv("page_10");' href="#">10</a> <a onClick='return showDiv("page_11");' href="#">11</a> <a onClick='return showDiv("page_12");' href="#">12</a> <a onClick='return showDiv("page_13");' href="#">13</a> <a onClick='return showDiv("page_14");' href="#">14</a> <a onClick='return showDiv("page_15");' href="#">15</a> <a onClick='return showDiv("page_16");' href="#">16</a> <a onClick='return showDiv("page_17");' href="#">17</a> <a style="font-weight: bold;">18</a> <a onClick='return showDiv("page_19");' href="#">19</a> <a onClick='return showDiv("page_20");' href="#">20</a> <a onClick='return showDiv("page_21");' href="#">21</a> <a onClick='return showDiv("page_22");' href="#">22</a> <a onClick='return showDiv("page_23");' href="#">23</a> <a onClick='return showDiv("page_24");' href="#">24</a> <a onClick='return showDiv("page_25");' href="#">25</a> </span> </span> <a id="NextPageLink" onclick='return showDiv("page_19");' href="#" title="Next Page"> <img id="NextPageLinkImage" class="Icon" src="http://www.science.gov/scigov/images/icon.next.18x20.png" alt="Next Page" /></a> <a id="LastPageLink" onclick='return showDiv("page_25.0");' href="#" title="Last Page"> <img id="LastPageLinkImage" class="Icon" src="http://www.science.gov/scigov/images/icon.last.18x20.png" alt="Last Page" /></a> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">341</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.ncbi.nlm.nih.gov/pubmed/11144312"> <span id="translatedtitle">Outcome of 306 <span class="hlt">twin</span> deliveries according to first <span class="hlt">twin</span> presentation and method of delivery.</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p class="result-summary">The objective of this manuscript is to examine the effect of presentation of the first <span class="hlt">twin</span> and mode of delivery on perintal outcome in <span class="hlt">twin</span> deliveries. We reviewed all records of <span class="hlt">twin</span> deliveries at a gestational age of 32 weeks and more from January 1, 1989 to December 31, 1995. Study cases were divided according to the first <span class="hlt">twin</span> presentation (vertex = group A, nonvertex = group B) and then subdivided according to the planned mode of delivery, vaginal trial of labor (VTOL), and cesarean section (CS). The protocol for group A facilitated an attempt at vaginal delivery and for group B, vaginal delivery was considered as for a singleton fetus in breech presentation. Of 306 pairs of <span class="hlt">twins</span>, 235 were in group A and 71 in group B. In group A, 219 women (93.2%) were eligible for VTOL, and the remaining 16 underwent CS. Thirty-three group B women were eligible for VTOL (46.5%; p<0.001) and 38 had CS. In group A, of the 219 candidates for VTOL, 199 (90.9%) delivered vaginally and 20 underwent a CS. In group B, of the 33 VTOL candidates 18 (54.5%) delivered vaginally and 15 underwent CS. Neonatal outcome did not differ in relation to the presentation of the first <span class="hlt">twin</span> or the planned/actual mode of delivery. There were no cases of birth trauma, neurological complications, or perinatal mortality. Trial of vaginal labor is safe in <span class="hlt">twin</span> deliveries with the first <span class="hlt">twin</span> in vertex presentation. Provided criteria for vaginal breech delivery are adhered to, this also appears to be a reasonable option in <span class="hlt">twin</span> deliveries with the first <span class="hlt">twin</span> in nonvertex presentation. PMID:11144312</p> <div class="credits"> <p class="dwt_author">Grisaru, D; Fuchs, S; Kupferminc, M J; Har-Toov, J; Niv, J; Lessing, J B</p> <p class="dwt_publisher"></p> <p class="publishDate">2000-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">342</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.ncbi.nlm.nih.gov/pubmed/10091627"> <span id="translatedtitle">Differential clinical and motor control function in a pair of monozygotic <span class="hlt">twins</span> with Huntington's disease.</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p class="result-summary">We report a pair of monozygotic Huntington's disease (HD) <span class="hlt">twins</span> who, although sharing identical CAG repeat lengths, not only present with marked differences in clinical symptoms but also behavioral abilities as measured by our experimental procedures. Both HD <span class="hlt">twins</span> and two <span class="hlt">healthy</span> control subjects were tested twice over 2 years. Patient A was generally more impaired at a motor level, whereas Patient B showed greater attentional impairment; Patient B, however, showed more progressive deterioration. The control subjects' performance remained consistent over the 2-year interval. Patient A clinically had the more hyperkinetic hypotonic variant of the disease, whereas Patient B, who was the more impaired, presented with a more hypokinetic hypertonic (rigid) variant. The influences of epigenetic pre- and postnatal environmental factors should not be ignored. PMID:10091627</p> <div class="credits"> <p class="dwt_author">Georgiou, N; Bradshaw, J L; Chiu, E; Tudor, A; O'Gorman, L; Phillips, J G</p> <p class="dwt_publisher"></p> <p class="publishDate">1999-03-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">343</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.ncbi.nlm.nih.gov/pubmed/11931691"> <span id="translatedtitle">Yoruba customs and beliefs pertaining to <span class="hlt">twins</span>.</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p class="result-summary">The Yoruba are an important ethnic group mainly occupying Southwestern Nigeria. Mainly for genetic reasons, this very large tribe happens to present the highest dizygotic <span class="hlt">twinning</span> rate in the world (4.4 % of all maternities). The high perinatal mortality rate associated with such pregnancies has contributed to the integration of a special <span class="hlt">twin</span> belief system within the African traditional religion of this tribe. The latter is based on the concept of a supreme deity called Olodumare or Olorun, assisted by a series of secondary gods (Orisha) while Yoruba religion also involves immortality and reincarnation of the soul based on the animistic cult of ancestors. <span class="hlt">Twins</span> are therefore given special names and believed to detain special preternatural powers. In keeping with their refined artistic tradition, the Yoruba have produced numerous wooden statuettes called Ibejis that represent the souls of deceased newborn <span class="hlt">twins</span> and are involved in elaborate rituals. Among Yoruba traditional beliefs and lore some <span class="hlt">twin</span>-related themes are represented which are also found in other parts of the world. Basic features of the original Yoruba beliefs have found their way into the religious traditions of descendants of African slaves imported in the West Indies and in South America. PMID:11931691</p> <div class="credits"> <p class="dwt_author">Leroy, Fernand; Olaleye-Oruene, Taiwo; Koeppen-Schomerus, Gesina; Bryan, Elizabeth</p> <p class="dwt_publisher"></p> <p class="publishDate">2002-04-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">344</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://ntrs.nasa.gov/search.jsp?R=19910019855&hterms=otter+speed&qs=N%3D0%26Ntk%3DAll%26Ntx%3Dmode%2Bmatchall%26Ntt%3Dotter%2527s%2Bspeed"> <span id="translatedtitle">NAE <span class="hlt">Twin</span> Otter operations in FIFE 1989</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p class="result-summary">During the summer of 1989, the National Aeronautical Establishment (Canada) <span class="hlt">Twin</span> Otter Atmospheric Research Aircraft was flow in support of the NASA sponsored First ISLSCP (International Satellite Land Surface Climatology Project) Field Experiment called FIFE-89. Airborne measurements of the fluxes of heat, momentum, water vapor and carbon dioxide were made during 16 flow-altitude flights over the FIFE project area in central Kansas. The <span class="hlt">Twin</span> Otter operations in FIFE are documented and details are included on the instrumentation, software, flight procedures, atmospheric conditions and analysis methods. Comparisons of <span class="hlt">Twin</span> Otter measured fluxes are made with those determined at several surface sites and with those made by other instrumented aircraft in the FIFE-87 measurements. Airborne flux measurements are related to run length, altitude, and environmental parameters such as vegetation type, temperature, and wind speed. One night flight was run in an attempt to measure the respiration component of the CO2 flux. The use of aircraft was studied for regional observations of fluxes and to relate these to satellite radiance measurements. Run average data are presented for all 285 flux runs flown by the <span class="hlt">Twin</span> Otter in FIFE-89. This should serve as as a working reference for scientists utilizing <span class="hlt">Twin</span> Otter data either directly of through the FIFE data archive.</p> <div class="credits"> <p class="dwt_author">Macpherson, J. I.</p> <p class="dwt_publisher"></p> <p class="publishDate">1990-01-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">345</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1493656"> <span id="translatedtitle">Surgical experience with thirteen conjoined <span class="hlt">twins</span>.</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p class="result-summary">Conjoined <span class="hlt">twins</span> occur in approximately one in 50,000 or so births, and most do not survive. The authors report herein their experience with 13 conjoined <span class="hlt">twins</span> over the last 30 years, involving those of the following forms: thoracopagus (4 cases), omphalopagus (1 case), ischiopagus (4 cases), pygopagus (1 case), craniopagus (1 case), and incomplete or parasitic varieties (2 cases). The various diagnostic and imaging studies used are described in detail for each form of <span class="hlt">twinning</span>. Separation is best delayed until such infants are relatively mature (i.e., 6-12 months of age). Operative survival was 50% in those operated on in the neonatal period, but 90% in those over 4 months of age. Ten separations were attempted in 13 sets of <span class="hlt">twins</span>, with 16 operative survivors. Significantly, up to 10 years after surgery, there were six late deaths due to serious associated congenital anomalies, predominantly cardiac. Improved recent survival is probably the result of the availability of more accurate imaging studies and better anesthetic and operative techniques, with great emphasis on performing immediate reconstruction whenever possible. Use of skin expanders and prosthetic mesh has facilitated wound closure. In the future, ex vivo cardiac reconstruction and autotransplantation may permit separation of <span class="hlt">twins</span> with complicated conjoined hearts. Images Fig. 1. Fig. 2. Fig. 3. Fig. 4. Fig. 5. Fig. 6. PMID:3421755</p> <div class="credits"> <p class="dwt_author">O'Neill, J A; Holcomb, G W; Schnaufer, L; Templeton, J M; Bishop, H C; Ross, A J; Duckett, J W; Norwood, W I; Ziegler, M M; Koop, C E</p> <p class="dwt_publisher"></p> <p class="publishDate">1988-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">346</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.ncbi.nlm.nih.gov/pubmed/16162644"> <span id="translatedtitle">Body odor similarity in noncohabiting <span class="hlt">twins</span>.</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p class="result-summary">There is currently considerable interest in biometric approaches using human odor as a marker of disease or genetic individuality. Body odor is also thought to be used during mate choice to select genetically compatible mates. The idea that body odor reveals information about both genetic identity and genetic similarity is most readily tested by examining odor in <span class="hlt">twin</span> pairs. However, although this idea can be traced back 130 years to Francis Galton in 1875, most studies using dogs fail to control for shared environmental effects associated with cohabitation. Here we show that odors of identical <span class="hlt">twins</span> (but not dizygotic <span class="hlt">twins</span>) can be matched by human sniffers at rates better than chance, even when the <span class="hlt">twins</span> are living apart. In addition, matching frequencies for identical <span class="hlt">twin</span> odors were not significantly different from those for duplicate odors from the same individual. These results indicate an important genetic influence on body odor and the potential for developing technologies for human odor printing in relation to underlying genotype. PMID:16162644</p> <div class="credits"> <p class="dwt_author">Roberts, S Craig; Gosling, L Morris; Spector, Tim D; Miller, Paul; Penn, Dustin J; Petrie, Marion</p> <p class="dwt_publisher"></p> <p class="publishDate">2005-10-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">347</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://adsabs.harvard.edu/abs/2008A%26A...489..677P"> <span id="translatedtitle">Solar <span class="hlt">twins</span> in M 67</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p class="result-summary">Context: The discovery of true solar analogs is fundamental to a better understanding of the Sun and of the solar system. Despite a number of efforts, this search has brought only limited results for field stars. The open cluster M 67 offers a unique opportunity to search for solar analogs, because its chemical composition and age are very similar to those of the Sun. Aims: We analyse FLAMES spectra of a large number of M 67 main sequence stars to identify solar analogs in this cluster. Methods: We first determined cluster members that are not likely binaries, by combining proper motions and radial velocity measurements. We concentrate our analysis on determining stellar effective temperature, using analyses of line-depth ratios and H? wing and making a direct comparison to the solar spectrum obtained with the same instrument. We also computed the lithium abundance for all the stars. Results: Ten stars have the temperature derived both by line-depth ratios and by the H? wings within 100 K from the Sun. From these stars we derive, assuming a cluster reddening E(B-V)=0.041, the solar color (B-V)_?=0.649±0.016 and a cluster distance modulus of 9.63. Five stars are most similar (within 60 K) to the Sun and candidates to be true solar <span class="hlt">twins</span>. These stars also have a low Li content, comparable to the photospheric abundance of the Sun, likely indicating a similar mixing evolution. Conclusions: We find several candidates for the best solar analogs ever. These stars are amenable to further spectroscopic investigations and planet searches. The solar colors are determined with fairly high accuracy with an independent method, as is the cluster distance modulus. Based on observations collected at the ESO VLT, Paranal Observatory, Chile, program 278.D-5027(A). Appendix ;A is only available in electronic form at http://www.aanda.org</p> <div class="credits"> <p class="dwt_author">Pasquini, L.; Biazzo, K.; Bonifacio, P.; Randich, S.; Bedin, L. R.</p> <p class="dwt_publisher"></p> <p class="publishDate">2008-10-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">348</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://arxiv.org/pdf/0807.0092v1"> <span id="translatedtitle">Solar <span class="hlt">twins</span> in M67</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.osti.gov/epsearch/">E-print Network</a></p> <p class="result-summary">The discovery of true solar analogues is fundamental for a better understanding of the Sun and of the solar system. The open cluster M67 offers a unique opportunity to search for solar analogues because its chemical composition and age are very similar to those of the Sun. We analyze FLAMES spectra of a large number of M67 main sequence stars to identify solar analogues in this cluster.We first determine cluster members which are likely not binaries, by combining proper motions and radial velocity measurements. We concentrate our analysis on the determination of stellar effective temperature, using analyses of line-depth ratios and H$\\alpha$ wings, making a direct comparison with the solar spectrum obtained with the same instrument. We also compute the lithium abundance for all the stars.Ten stars have both the temperature derived by line-depth ratios and H$\\alpha$ wings within 100 K from the Sun. From these stars we derive, assuming a cluster reddening $E(B-V)=0.041$, the solar colour $(B-V)_\\odot=0.649\\pm0.016$ and a cluster distance modulus of 9.63. Five stars are most similar (within 60 K) to the Sun and candidates to be true solar <span class="hlt">twins</span>. These stars have also a low Li content, comparable to the photospheric abundance of the Sun, likely indicating a similar mixing evolution. We find several candidates for the best solar analogues ever. These stars are amenable to further spectroscopic investigations and planet search. The solar colours are determined with rather high accuracy with an independent method, as well as the cluster distance modulus.</p> <div class="credits"> <p class="dwt_author">L. Pasquini; K. Biazzo; P. Bonifacio; S. Randich; L. Bedin</p> <p class="dwt_publisher"></p> <p class="publishDate">2008-07-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">349</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.entnet.org/content/tips-healthy-voices"> <span id="translatedtitle">Tips for <span class="hlt">Healthy</span> Voices</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://medlineplus.gov/">MedlinePLUS</a></p> <p class="result-summary">Tips for <span class="hlt">Healthy</span> Voices Tips for <span class="hlt">Healthy</span> Voices Patient Health Information News media interested in covering the latest from AAO-HNS/F can find information on embargoes, Annual Meeting press registration ...</p> <div class="credits"> <p class="dwt_author"></p> <p class="dwt_publisher"></p> <p class="publishDate"></p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">350</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://genepi.qimr.edu.au/general/daleN/papers/Souter2006HumGenet.pdf"> <span id="translatedtitle">A case of true hermaphroditism reveals an unusual mechanism of <span class="hlt">twinning</span></span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://academic.research.microsoft.com/">Microsoft Academic Search </a></p> <p class="result-summary">Traditionally <span class="hlt">twins</span> are classified as dizygous or fraternal and monozygous or identical (Hall <span class="hlt">Twinning</span>, 362, 2003 and 735–743). We report a rare case of 46,XX\\/46,XY <span class="hlt">twins</span>: <span class="hlt">Twin</span> A presented with ambiguous genitalia and <span class="hlt">Twin</span> B was a phenotypically\\u000a normal male. These <span class="hlt">twins</span> demonstrate a third, previously unreported mechanism for <span class="hlt">twinning</span>. The <span class="hlt">twins</span> underwent initial investigation\\u000a with 17-hydroxyprogesterone and testosterone levels,</p> <div class="credits"> <p class="dwt_author">Vivienne L. Souter; Melissa A. Parisi; Dale R. Nyholt; Raj P. Kapur; Anjali K. Henders; Kent E. Opheim; Daniel F. Gunther; Michael E. Mitchell; Ian A. Glass; Grant W. Montgomery</p> <p class="dwt_publisher"></p> <p class="publishDate">2007-01-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">351</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2279116"> <span id="translatedtitle">Single mitochondrial gene barcodes reliably identify <span class="hlt">sister</span>-species in diverse clades of birds</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p class="result-summary">Background DNA barcoding of life using a standardized COI sequence was proposed as a species identification system, and as a method for detecting putative new species. Previous tests in birds showed that individuals can be correctly assigned to species in ~94% of the cases and suggested a threshold of 10× mean intraspecific difference to detect potential new species. However, these tests were criticized because they were based on a single maternally inherited gene rather than multiple nuclear genes, did not compare phylogenetically identified <span class="hlt">sister</span> species, and thus likely overestimated the efficacy of DNA barcodes in identifying species. Results To test the efficacy of DNA barcodes we compared ~650 bp of COI in 60 <span class="hlt">sister</span>-species pairs identified in multigene phylogenies from 10 orders of birds. In all pairs, individuals of each species were monophyletic in a neighbor-joining (NJ) tree, and each species possessed fixed mutational differences distinguishing them from their <span class="hlt">sister</span> species. Consequently, individuals were correctly assigned to species using a statistical coalescent framework. A coalescent test of taxonomic distinctiveness based on chance occurrence of reciprocal monophyly in two lineages was verified in known <span class="hlt">sister</span> species, and used to identify recently separated lineages that represent putative species. This approach avoids the use of a universal distance cutoff which is invalidated by variation in times to common ancestry of <span class="hlt">sister</span> species and in rates of evolution. Conclusion Closely related <span class="hlt">sister</span> species of birds can be identified reliably by barcodes of fixed diagnostic substitutions in COI sequences, verifying coalescent-based statistical tests of reciprocal monophyly for taxonomic distinctiveness. Contrary to recent criticisms, a single DNA barcode is a rapid way to discover monophyletic lineages within a metapopulation that might represent undiscovered cryptic species, as envisaged in the unified species concept. This identifies a smaller set of lineages that can also be tested independently for species status with multiple nuclear gene approaches and other phenotypic characters. PMID:18328107</p> <div class="credits"> <p class="dwt_author"></p> <p class="dwt_publisher"></p> <p class="publishDate">2008-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">352</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3749309"> <span id="translatedtitle">A <span class="hlt">Twin</span> Study of Alcohol Dependence, Binge Eating, and Compensatory Behaviors</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p class="result-summary">Objective: Rates of alcohol dependence are elevated in women with eating disorders who engage in binge eating or compensatory behaviors compared with women with eating disorders who do not report binge eating or compensatory behaviors and with <span class="hlt">healthy</span> controls. Alcohol dependence, binge eating, and compensatory behaviors are heritable; however, it is unclear whether a shared genetic liability contributes to the phenotypic association among these traits, and little information exists regarding this shared liability in men. We investigated genetic and environmental correlations among alcohol dependence, binge eating, and compensatory behaviors in male and female <span class="hlt">twins</span>. Method: Participants included 5,993 same- and opposite-sex <span class="hlt">twins</span> from the Australian <span class="hlt">Twin</span> Registry who completed a modified version of the Semi-Structured Assessment for the Genetics of Alcoholism that assessed lifetime alcohol dependence and binge eating as defined in the Diagnostic and Statistical Manual of Mental Disorders, Third Edition, Revised. Compensatory behaviors were assessed via a general health questionnaire in women only. Biometrical <span class="hlt">twin</span> models estimated genetic and environmental influences on alcohol dependence, binge eating, and compensatory behaviors. Results: In women, the multivariate <span class="hlt">twin</span> model suggested that additive genetic and nonshared environmental effects influenced alcohol dependence, binge eating, and compensatory behaviors, with heritability estimates ranging from 38% to 53%. The best-fitting sex-limitation model was a common effects model that equated all genetic and nonshared environmental influences in men and women. The heritability estimates were 50% and 38% for alcohol dependence and binge eating, respectively. Overall, there were significant genetic correlations between alcohol dependence and binge eating, alcohol dependence and compensatory behaviors, and binge eating and compensatory behaviors. Conclusions: These findings indicate that common genetic factors may underlie the vulnerability to alcohol dependence and the liability to binge eating and compensatory behaviors. PMID:23948525</p> <div class="credits"> <p class="dwt_author">Munn-Chernoff, Melissa A.; Duncan, Alexis E.; Grant, Julia D.; Wade, Tracey D.; Agrawal, Arpana; Bucholz, Kathleen K.; Madden, Pamela A. F.; Martin, Nicholas G.; Heath, Andrew C.</p> <p class="dwt_publisher"></p> <p class="publishDate">2013-01-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">353</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3635202"> <span id="translatedtitle">Bellagio Report on <span class="hlt">Healthy</span> Agriculture, <span class="hlt">Healthy</span> Nutrition, <span class="hlt">Healthy</span> People</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p class="result-summary">The Bellagio Report on <span class="hlt">Healthy</span> Agriculture, <span class="hlt">Healthy</span> Nutrition, <span class="hlt">Healthy</span> People is the result of the meeting held at the Rockefeller Foundation Bellagio Center in Lake Como, Italy, 29 October–2 November 2012. The meeting was science-based but policy-oriented. The role and amount of <span class="hlt">healthy</span> and unhealthy fats, with attention to the relative content of omega-3 and omega-6 fatty acids, sugar, and particularly fructose in foods that may underlie the epidemics of non-communicable diseases (NCD’s) worldwide were extensively discussed. The report concludes that sugar consumption, especially in the form of high energy fructose in soft drinks, poses a major and insidious health threat, especially in children, and most diets, although with regional differences, are deficient in omega-3 fatty acids and too high in omega-6 fatty acids. Gene-nutrient interactions in growth and development and in disease prevention are fundamental to health, therefore regional Centers on Genetics, Nutrition and Fitness for Health should be established worldwide. Heads of state and government must elevate, as a matter of urgency, Nutrition as a national priority, that access to a <span class="hlt">healthy</span> diet should be considered a human right and that the lead responsibility for Nutrition should be placed in Ministries of Health rather than agriculture so that the health requirements drive agricultural priorities, not vice versa. Nutritional security should be given the same priority as food security. PMID:23385371</p> <div class="credits"> <p class="dwt_author">Simopoulos, Artemis P.; Bourne, Peter G.; Faergeman, Ole</p> <p class="dwt_publisher"></p> <p class="publishDate">2013-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">354</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://adsabs.harvard.edu/abs/1993IJBm...37..145N"> <span id="translatedtitle">Low <span class="hlt">twinning</span> rate and seasonal effects on <span class="hlt">twinning</span> in a fertile population, the Hutterites</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p class="result-summary">This paper analyzes from the mid 18th century to 1987 the birth records of the “Dariusleut,” one of the three subgroups of the Hutterite population. The aim of this study is to describe several aspects of the <span class="hlt">twinning</span> rate in a fertile population. The overall rate of <span class="hlt">twinning</span> was 0.90%:103 <span class="hlt">twins</span> among all 11492 maternities. The rate peaked at the 7th birth order and at the maternal age of 40 years and over. Until the mid 19th century when the Hutterites lived in Russia, the <span class="hlt">twinning</span> rate was higher (1.5%), and it decreased during the migration period in the second half of the 19th century (0.7%). After the group had settled in the USA and Canada, the population maintained a <span class="hlt">twinning</span> rate of 1.0% until 1965. After 1965 the rate decreased to 0.7%, partly due to a decline in fertility among women aged 30 years and over. There was a significant seasonal variation: the <span class="hlt">twinning</span> rate decreased to 0.5% in May July compared to 1.2% for the other three seasons during the years up to 1965 ( P<0.01), while more recent mothers did not show such a seasonal variation. The incidence of <span class="hlt">twin</span> births in this population seems to have been influenced by environmental factors, which would change their effect seasonally and secularly.</p> <div class="credits"> <p class="dwt_author">Nonaka, K.; Miura, T.; Peter, K.</p> <p class="dwt_publisher"></p> <p class="publishDate">1993-09-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">355</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.ncbi.nlm.nih.gov/pubmed/25077476"> <span id="translatedtitle">Role of adjunctive medical therapy in the fetoscopic surgical treatment of <span class="hlt">twin-twin</span> transfusion syndrome.</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p class="result-summary">The underlying etiology of <span class="hlt">twin-twin</span> transfusion syndrome (TTTS) is unknown, but our growing understanding of the cardiovascular features of TTTS suggests this may be a disease that could respond to transplacental medical therapy. Adjunctive medical therapy in TTTS with the calcium channel blocker nifedipine has been shown to improve recipient survival while having no effect on the donor. There is no significant difference in recipient survival from postoperative day 5 to birth suggesting that the survival benefit is confined to the effects of nifedipine in the perioperative period. Also, there is no significant effect of nifedipine on gestational age at delivery suggesting the survival benefit was unrelated to the tocolytic effects of nifedipine and more likely a result of hemodynamic effects in the recipient <span class="hlt">twins</span>' cardiovascular system during the perioperative period. TTTS remains poorly understood but there appears to be good evidence suggesting <span class="hlt">twin-twin</span> hypertensive cardiomyopathy is a large component of the pathophysiology in recipient <span class="hlt">twins</span>. The initial findings of nifedipine's effectiveness as a targeted medical therapy to address TTTS cardiomyopathy and improve survival of recipient <span class="hlt">twins</span> opens the door for further research for adjunctive medical therapies in TTTS. PMID:25077476</p> <div class="credits"> <p class="dwt_author">Zaretsky, Michael V; Somme, Stig; Crombleholme, Timothy M</p> <p class="dwt_publisher"></p> <p class="publishDate">2014-09-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">356</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.loc.gov/pictures/collection/hh/item/ut0346.photos.159541p/"> <span id="translatedtitle">3. OVERALL VIEW OF <span class="hlt">TWIN</span> POTS RESERVOIR, LOOKING SOUTHEAST ...</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.loc.gov/pictures/collection/hh/">Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey</a></p> <p class="result-summary">3. OVERALL VIEW OF <span class="hlt">TWIN</span> POTS RESERVOIR, LOOKING SOUTHEAST - High Mountain Dams in Upalco Unit, <span class="hlt">Twin</span> Pots Dam, Ashley National Forest, 10.1 miles North of Mountain Home, Mountain Home, Duchesne County, UT</p> <div class="credits"> <p class="dwt_author"></p> <p class="dwt_publisher"></p> <p class="publishDate"></p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">357</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.ncbi.nlm.nih.gov/pubmed/11684762"> <span id="translatedtitle">[Human clone or a delayed <span class="hlt">twin</span>?].</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p class="result-summary">Cloning is a natural mode of asexual reproduction for many organisms, which results in nearly identical copies of cells or organisms. In animals, including humans, identical <span class="hlt">twins</span> are an example of natural cloning. In the case of sheep, scientists succeeded to produce the "delayed" identical <span class="hlt">twin</span>. Dolly, of a mature animal by a rather complex and inefficient procedure. However, if this procedure is perfected, it will be useful to clone beloved pets and important laboratory animals. It will be much less suited for making (cloning) "delayed <span class="hlt">twin</span>" of mature persons because of high costs together with present experimental uncertainties. The only required regulation for human cloning is that somebody must be legally, including financially, responsible for the results of such novel reproductive technique. PMID:11684762</p> <div class="credits"> <p class="dwt_author">Szybalski, W</p> <p class="dwt_publisher"></p> <p class="publishDate">2001-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">358</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.eatright.org/Public/content.aspx?id=10934"> <span id="translatedtitle"><span class="hlt">Healthy</span> Weights for <span class="hlt">Healthy</span> Older Adults</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://medlineplus.gov/">MedlinePLUS</a></p> <p class="result-summary">... Intolerances Autism Cancer Celiac Disease Diabetes Digestive Health Eating Disorders Fertility and Reproductive Health Heart and Cardiovascular HIV/ ... range of topics including careers in dietetics, <span class="hlt">healthy</span> eating, the Academy ... benefits, media interviewing skills and the professional role of the ...</p> <div class="credits"> <p class="dwt_author"></p> <p class="dwt_publisher"></p> <p class="publishDate"></p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">359</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.ncbi.nlm.nih.gov/pubmed/2335017"> <span id="translatedtitle">The incidence of <span class="hlt">twins</span> in care.</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p class="result-summary">The birth of <span class="hlt">twins</span>, triplets or more is usually a reason for great celebration. Evidence suggests, however, that in some circumstances a multiple birth creates serious difficulties for parents and may cause enormous stress within a family. One crude indicator of family breakdown is the reception of children into Local Authority care: during 1988, the author attempted to establish the incidence of <span class="hlt">twins</span> in care (or on social workers' caseloads where preventive work was being done) by gathering figures from Directors of Social Services in Local Authorities in England, Wales and Northern Ireland. Whilst analysis of the figures at first suggests that there is no over-representation of 'multiples' in Local Authority care, it is suggested that the results of the first survey should be treated with caution. The majority of Local Authorities have not so far identified <span class="hlt">twins</span>, etc., on their records (nor, indeed, has the Department of Social Services) and so identification had to be done on a 'common surname and date of birth' basis, where that was possible. Many single <span class="hlt">twins</span> would thus be missed. Only 36% of Local Authorities were able to provide complete figures for sets of <span class="hlt">twins</span> in care. Reliable data for the incidence of <span class="hlt">twins</span> on social workers' caseloads (children not in care) proved impossible to collect. Information about multiples should be much easier to obtain in the future. Many Local Authorities are now installing or operating computer systems. Over half of those Directors who could not provide figures at the moment indicated that they would be able to do so on a future occasion. PMID:2335017</p> <div class="credits"> <p class="dwt_author">Broadbent, B A</p> <p class="dwt_publisher"></p> <p class="publishDate">1990-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">360</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1721704"> <span id="translatedtitle">Preterm <span class="hlt">twin</span> gestation and cystic periventricular leucomalacia</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p class="result-summary">Objective: To identify risk factors for the development of cystic periventricular leucomalacia (PVL) in <span class="hlt">twin</span> gestation. Design: Retrospective case-control study. Setting: Tertiary care university hospital, Department of Paediatrics, Division of Neonatology, Graz, Austria. Patients: Preterm <span class="hlt">twin</span> gestations with one sibling having developed cystic PVL, diagnosed by ultrasound scans, compared with their co-<span class="hlt">twins</span> without PVL, in hospital between 1988 and 2000. Main outcome measures: Perinatal and postnatal risk factors for the development of PVL. Results: Eighteen preterm <span class="hlt">twin</span> gestations were included. Monochorionicity was evident in 47% of the pregnancies, and <span class="hlt">twin</span> to <span class="hlt">twin</span> transfusion syndrome occurred in two cases (11%). Fetal distress correlated inversely with PVL (15% v 53%, p  =  0.019, relative risk (RR)  =  2.057, 95% confidence interval (CI)  =  1.067 to 3.968). Hypocarbia with PCO2 levels below 30 mm Hg (4 kPa) was diagnosed in 29% of the cases compared with 6% of the controls (p  =  0.038, RR  =  1.944, 95% CI  =  1.113 to 3.396). There were no significant differences between groups with regard to premature rupture of the membranes, early onset infection, respiratory distress syndrome, mechanical ventilation, arterial hypotension, persistent ductus arteriosus, and hyperbilirubinaemia. Asphyxia was only evident in three controls. Three infants died and another three were lost to follow up. None of the cases compared with 62% of the controls were diagnosed as having developed normally (p < 0.001), and 14 cases (82%) compared with two controls (15%) developed cerebral palsy (p < 0.001). Conclusion: Hypocarbia was the only risk factor strongly associated with cystic PVL. The general outcome of the infants was poor. PMID:15210663</p> <div class="credits"> <p class="dwt_author">Resch, B; Jammernegg, A; Vollaard, E; Maurer, U; Mueller, W; Pertl, B</p> <p class="dwt_publisher"></p> <p class="publishDate">2004-01-01</p> </div> </div> </div> </div> <div id="filter_results_form" class="filter_results_form floatContainer" style="visibility: visible;"> <div style="width:100%" id="PaginatedNavigation" class="paginatedNavigationElement"> <a id="FirstPageLink" onclick='return showDiv("page_1");' href="#" title="First Page"> <img id="FirstPageLinkImage" class="Icon" src="http://www.science.gov/scigov/images/icon.first.18x20.png" alt="First Page" /></a> <a id="PreviousPageLink" onclick='return showDiv("page_17");' href="#" title="Previous Page"> <img id="PreviousPageLinkImage" class="Icon" src="http://www.science.gov/scigov/images/icon.previous.18x20.png" alt="Previous Page" /></a> <span id="PageLinks" class="pageLinks"> <span> <a onClick='return showDiv("page_1");' href="#">1</a> <a onClick='return 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class="paginatedNavigationElement"> <a id="FirstPageLink" onclick='return showDiv("page_1");' href="#" title="First Page"> <img id="FirstPageLinkImage" class="Icon" src="http://www.science.gov/scigov/images/icon.first.18x20.png" alt="First Page" /></a> <a id="PreviousPageLink" onclick='return showDiv("page_18");' href="#" title="Previous Page"> <img id="PreviousPageLinkImage" class="Icon" src="http://www.science.gov/scigov/images/icon.previous.18x20.png" alt="Previous Page" /></a> <span id="PageLinks" class="pageLinks"> <span> <a onClick='return showDiv("page_1");' href="#">1</a> <a onClick='return showDiv("page_2");' href="#">2</a> <a onClick='return showDiv("page_3");' href="#">3</a> <a onClick='return showDiv("page_4");' href="#">4</a> <a onClick='return showDiv("page_5");' href="#">5</a> <a onClick='return showDiv("page_6");' href="#">6</a> <a onClick='return showDiv("page_7");' href="#">7</a> <a onClick='return showDiv("page_8");' href="#">8</a> <a onClick='return 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title="Next Page"> <img id="NextPageLinkImage" class="Icon" src="http://www.science.gov/scigov/images/icon.next.18x20.png" alt="Next Page" /></a> <a id="LastPageLink" onclick='return showDiv("page_25.0");' href="#" title="Last Page"> <img id="LastPageLinkImage" class="Icon" src="http://www.science.gov/scigov/images/icon.last.18x20.png" alt="Last Page" /></a> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">361</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://cdsweb.cern.ch/record/1753986"> <span id="translatedtitle">The <span class="hlt">twin</span> paradox in the presence of gravity</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.osti.gov/epsearch/">E-print Network</a></p> <p class="result-summary">Conventional wisdom, based on kinematic (flat-space) intuition, tell us that a static <span class="hlt">twin</span> is aging faster than his traveling <span class="hlt">twin</span> brother. However, such a situation could be exactly inverted if the two <span class="hlt">twins</span> are embedded in an external gravitational field, and if the (dynamical) distortion of the space-time geometry, due to gravity, is strong enough to compensate the kinematic effect of the relative <span class="hlt">twin</span> motion.</p> <div class="credits"> <p class="dwt_author">Gasperini, M</p> <p class="dwt_publisher"></p> <p class="publishDate">2014-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">362</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://arxiv.org/pdf/1409.1818v1"> <span id="translatedtitle">The <span class="hlt">twin</span> paradox in the presence of gravity</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.osti.gov/epsearch/">E-print Network</a></p> <p class="result-summary">Conventional wisdom, based on kinematic (flat-space) intuition, tell us that a static <span class="hlt">twin</span> is aging faster than his traveling <span class="hlt">twin</span> brother. However, such a situation could be exactly inverted if the two <span class="hlt">twins</span> are embedded in an external gravitational field, and if the (dynamical) distortion of the space-time geometry, due to gravity, is strong enough to compensate the kinematic effect of the relative <span class="hlt">twin</span> motion.</p> <div class="credits"> <p class="dwt_author">M. Gasperini</p> <p class="dwt_publisher"></p> <p class="publishDate">2014-09-05</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">363</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.ncbi.nlm.nih.gov/pubmed/19956938"> <span id="translatedtitle">Fetal MRI of conjoined <span class="hlt">twins</span> who switched their relative positions.</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p class="result-summary">Conjoined <span class="hlt">twinning</span> is a very rare occurrence with no genetic predisposition. Twisting of conjoined <span class="hlt">twins</span> around the axis of their connecting tissue bridge, close to the third trimester, has not been previously reported. We describe a unique case of in utero twisting of conjoined omphalopagus <span class="hlt">twins</span> who survived without any adverse effects. Fetal US and fetal MRI played a vital role in the diagnosis and perinatal management of these <span class="hlt">twins</span>. PMID:19956938</p> <div class="credits"> <p class="dwt_author">Huisman, Thierry A G M; Arulrajah, Sahayini; Meuli, Martin; Brehmer, Ulrike; Beinder, Ernst</p> <p class="dwt_publisher"></p> <p class="publishDate">2010-03-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">364</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://ia.usu.edu/viewproject.php?project=ia:17032"> <span id="translatedtitle"><span class="hlt">Healthy</span> Foods for a <span class="hlt">Healthy</span> Body</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://nsdl.org/nsdl_dds/services/ddsws1-1/service_explorer.jsp">NSDL National Science Digital Library</a></p> <p class="result-summary">During this activity we will be learning about <span class="hlt">healthy</span> foods and why they are important to our bodies and minds. First thing is first, let's learn about what foods are <span class="hlt">healthy</span> and then move on to why we need them. Follow the link bellow and play the blast off game, enter in the foods closest to what you actually eat and the activities that you like and do. Blast Off Game After you ...</p> <div class="credits"> <p class="dwt_author">Mansfield, Miss</p> <p class="dwt_publisher"></p> <p class="publishDate">2011-08-05</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">365</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://pubs.er.usgs.gov/publication/70020853"> <span id="translatedtitle">Needle <span class="hlt">twins</span> and right-angled <span class="hlt">twins</span> in minerals: comparison between experiment and theory</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p class="result-summary">Transformation <span class="hlt">twinning</span> in minerals forms isolated <span class="hlt">twin</span> walls, intesecting walls with corner junctions, and wedge-shaped <span class="hlt">twins</span> as elements of hierarchical patterns. When cut perpendicular to the <span class="hlt">twin</span> walls, the <span class="hlt">twins</span> have characteristic shapes, right-angled and needle-shaped wall traces, which can be observed by transmission electron microscopy or by optical microscopy. Theoretical geometries of wall shapes recently derived for strain-related systems should hold for most displacive and order-disorder type phase transitions: 1) right-angled <span class="hlt">twins</span> show curved junctions; 2) needle-shaped <span class="hlt">twins</span> contain flat wall segments near the needle tip if the elastic behaviour of the mineral is dominated by its anisotroyp; 3) additional bending forces and pinning effects lead to curved walls near the junction that make the needle tip appear more blunt. Bent right-angled <span class="hlt">twins</span> were analyzed in Gd2(MoO4)3. Linear needle tips were found in WO3, [N(CH3)4]2.ZnBr4 CrAl, BiVO4, GdBa2Cu3O7, and PbZrO. Parabolic tips occur in K2Ba(NO2)4, and GeTe whereas exponential curvatures appear in BaTiO3, KSCN, Pb3(PO4)2, CaTiO3, alkali feldspars, YBa2Cu3O7, and MnAl. The size and shape of the <span class="hlt">twin</span> microstructure relates to its formation during the phase transition and the subsequent annealing history. The mobility of the <span class="hlt">twin</span> walls after formation depends not only on the thermal activation but also on the structure of the wall, which may be pinned to impurities on a favorable structural site. Depinnign energies are often large compared with thermal energies for diffusion. This leads to kinetic time scales for <span class="hlt">twin</span> coarsening that are comparable to geological time scales. Therefore, transformation <span class="hlt">twins</span> that exhibit needle domains not only indicate that the mineral underwent a structural phase transition but also contain information about its subsequent geological history.</p> <div class="credits"> <p class="dwt_author">Salje, E.K.H.; Buckley, A.; Van Tendeloo, G.; Ishibashi, Y.; Nord, G.L., Jr.</p> <p class="dwt_publisher"></p> <p class="publishDate">1998-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">366</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://arxiv.org/pdf/1408.6407v1"> <span id="translatedtitle">Low-noise macroscopic <span class="hlt">twin</span> beams</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.osti.gov/epsearch/">E-print Network</a></p> <p class="result-summary">Applying a multiphoton-subtraction technique to two-color macroscopic squeezed vacuum state of light generated via high-gain parametric down conversion we conditionally prepare a new state of light: bright multi-mode low-noise <span class="hlt">twin</span> beams. The obtained results demonstrate up to 8-fold suppression of noise in each beam while preserving and even moderately improving the nonclassical photon number correlations between the beams. The prepared low-noise macroscopic state, containing up to 2000 photons per mode, is not among the states achievable through nonlinear optical processes. The proposed technique substantially improves the usefulness of <span class="hlt">twin</span> beams for quantum technologies.</p> <div class="credits"> <p class="dwt_author">Timur Sh. Iskhakov; Vladyslav C. Usenko; Radim Filip; Maria V. Chekhova; Gerd Leuchs</p> <p class="dwt_publisher"></p> <p class="publishDate">2014-08-27</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">367</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.osti.gov/scitech/biblio/22051183"> <span id="translatedtitle">Role of <span class="hlt">twinning</span> in plastic deformation</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p class="result-summary">A new concept of the structure of yttrium-aluminum garnet (Y{sub 3}Al{sub 5}O{sub 12}) has demonstrated the possibility of forming inversion <span class="hlt">twins</span> in the (111) plane. The <span class="hlt">twinning</span> processes are shown to be responsible for stress relaxation during the growth and plastic deformation of Y{sub 3}Al{sub 5}O{sub 12} single crystals. This way of stress relaxation can be used to describe the plastic deformation of other crystals, at least cubic ones.</p> <div class="credits"> <p class="dwt_author">Akchurin, M. Sh., E-mail: akchurin@ns.crys.ras.ru; Zakalyukin, R. M.; Kaminsky, A. A.; Kupenko, I. I. [Russian Academy of Sciences, Shubnikov Institute of Crystallography (Russian Federation)</p> <p class="dwt_publisher"></p> <p class="publishDate">2010-07-15</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">368</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://adsabs.harvard.edu/abs/2002EJPh...23..277U"> <span id="translatedtitle">The <span class="hlt">twin</span> paradox and space topology</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p class="result-summary">If space is compact, then a traveller <span class="hlt">twin</span> can leave Earth, travel back home without changing direction and find her sedentary <span class="hlt">twin</span> older than herself. We show that the asymmetry between their spacetime trajectories lies in a topological invariant of their spatial geodesics, namely the homotopy class. This illustrates how the spacetime symmetry invariance group, although valid locally, is broken down globally as soon as some points of space are identified. As a consequence, any non-trivial space topology defines preferred inertial frames along which the proper time is longer than along any other one.</p> <div class="credits"> <p class="dwt_author">Uzan, Jean-Philippe; Luminet, Jean-Pierre; Lehoucq, Roland; Peter, Patrick</p> <p class="dwt_publisher"></p> <p class="publishDate">2002-05-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">369</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://cdsweb.cern.ch/record/1282747"> <span id="translatedtitle">The Myth of the <span class="hlt">Twin</span> Paradox</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.osti.gov/epsearch/">E-print Network</a></p> <p class="result-summary">One of the most discussed peculiarities of Einstein's theory of relativity is the <span class="hlt">twin</span> paradox, the fact that the time between two events in space-time appears to depend on the path between these events. We show that this time discrepancy results only from faulty assumptions in the transition from one reference system to another. The <span class="hlt">twin</span> paradox does not exist. But the Lorentz invariance of the theory has strong consequences, if we assume that it is valid not only locally, but also on cosmic scale.</p> <div class="credits"> <p class="dwt_author">Fischer, E</p> <p class="dwt_publisher"></p> <p class="publishDate">2010-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">370</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://arxiv.org/pdf/1008.0174v1"> <span id="translatedtitle">The Myth of the <span class="hlt">Twin</span> Paradox</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.osti.gov/epsearch/">E-print Network</a></p> <p class="result-summary">One of the most discussed peculiarities of Einstein's theory of relativity is the <span class="hlt">twin</span> paradox, the fact that the time between two events in space-time appears to depend on the path between these events. We show that this time discrepancy results only from faulty assumptions in the transition from one reference system to another. The <span class="hlt">twin</span> paradox does not exist. But the Lorentz invariance of the theory has strong consequences, if we assume that it is valid not only locally, but also on cosmic scale.</p> <div class="credits"> <p class="dwt_author">E. Fischer</p> <p class="dwt_publisher"></p> <p class="publishDate">2010-08-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">371</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://ruccs.rutgers.edu/~karin/StromRifkin_1996.pdf"> <span id="translatedtitle">Stromswold & Rifkin, Language Acquisition by MZ & DZ SLI <span class="hlt">Twins</span> (SRCLD, 1996) 1 Language Acquisition by Identical vs. Fraternal SLI <span class="hlt">Twins</span>*</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.osti.gov/epsearch/">E-print Network</a></p> <p class="result-summary">by Identical vs. Fraternal SLI <span class="hlt">Twins</span>* Karin Stromswold & Jay I. Rifkin Dept. of Psychology & Ctr. for Cognitive acquisition by sets of identical (monozygotic, MZ) and fraternal (dizygotic, DZ) <span class="hlt">twins</span> with specific language</p> <div class="credits"> <p class="dwt_author">Stromswold, Karin</p> <p class="dwt_publisher"></p> <p class="publishDate"></p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">372</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://admissions.tc.umn.edu/PDFs/transfer_credit.pdf"> <span id="translatedtitle">University of Minnesota-<span class="hlt">Twin</span> Cities Transfer Credit Resources</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.osti.gov/epsearch/">E-print Network</a></p> <p class="result-summary">University of Minnesota-<span class="hlt">Twin</span> Cities Transfer Credit Resources We recommend three online transfer-<span class="hlt">Twin</span> Cities has evaluated to satisfy our specific Liberal Education requirements. This guide is useful and Engineering (CSE) Transfer Plans and Equivalencies #12;University of Minnesota-<span class="hlt">Twin</span> Cities Transfer Credit</p> <div class="credits"> <p class="dwt_author">Amin, S. Massoud</p> <p class="dwt_publisher"></p> <p class="publishDate"></p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">373</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://genepi.qimr.edu.au/contents/p/staff/CV266.pdf"> <span id="translatedtitle">Genetic influences on premature parturition in an Australian <span class="hlt">twin</span> sample</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://academic.research.microsoft.com/">Microsoft Academic Search </a></p> <p class="result-summary">We investigated possible genetic influences on women's liability to preterm birth, using data from a large sample of Australian female <span class="hlt">twin</span> pairs. In a 1988-90 questionnaire survey, both members of 905 parous <span class="hlt">twin</span> pairs (579 monozygotic and 326 dizygotic) reported on whether deliveries had been more than two weeks preterm. Tetrachoric <span class="hlt">twin</span> pair correlations for first birth were rMZ =</p> <div class="credits"> <p class="dwt_author">Susan A Treloar; George A Macones; Laura E Mitchell; Nicholas G Martin</p> <p class="dwt_publisher"></p> <p class="publishDate">2000-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">374</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://eric.ed.gov/?q=genetic&pg=2&id=EJ1008327"> <span id="translatedtitle">A Multivariate <span class="hlt">Twin</span> Study of Early Literacy in Japanese "Kana"</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p class="result-summary">This first Japanese <span class="hlt">twin</span> study of early literacy development investigated the extent to which genetic and environmental factors influence individual differences in prereading skills in 238 pairs of <span class="hlt">twins</span> at 42 months of age. <span class="hlt">Twin</span> pairs were individually tested on measures of phonological awareness, "kana" letter name/sound knowledge, receptive…</p> <div class="credits"> <p class="dwt_author">Fujisawa, Keiko K.; Wadsworth, Sally J.; Kakihana, Shinichiro; Olson, Richard K.; DeFries, John C.; Byrne, Brian; Ando, Juko</p> <p class="dwt_publisher"></p> <p class="publishDate">2013-01-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">375</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.wellcome.ac.uk/stellent/groups/corporatesite/@policy_communications/documents/web_document/wtvm050959.pdf"> <span id="translatedtitle">CONSULTATION RESPONSE Wellcome Trust response to `<span class="hlt">Healthy</span> Lives, <span class="hlt">Healthy</span> People'</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.osti.gov/epsearch/">E-print Network</a></p> <p class="result-summary">CONSULTATION RESPONSE Wellcome Trust response to `<span class="hlt">Healthy</span> Lives, <span class="hlt">Healthy</span> People' March 2011 Page 1 of 4 Department of Health: <span class="hlt">Healthy</span> Lives, <span class="hlt">Healthy</span> People: Our Strategy for Public Health in England to `<span class="hlt">Healthy</span> Lives, <span class="hlt">Healthy</span> People' March 2011 Page 2 of 4 · research plays a vital role in informing</p> <div class="credits"> <p class="dwt_author">Rambaut, Andrew</p> <p class="dwt_publisher"></p> <p class="publishDate"></p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">376</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.osti.gov/scitech/biblio/22163174"> <span id="translatedtitle"><span class="hlt">Twin</span> nucleation and migration in FeCr single crystals</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p class="result-summary">Tension and compression experiments were conducted on body-centered cubic Fe -47.8 at pct. Cr single crystals. The critical resolved shear stress (CRSS) magnitudes for slip nucleation, <span class="hlt">twin</span> nucleation and <span class="hlt">twin</span> migration were established. We show that the nucleation of slip occurs at a CRSS of about 88 MPa, while <span class="hlt">twinning</span> nucleates at a CRSS of about 191 MPa with an associated load drop. Following <span class="hlt">twin</span> nucleation, <span class="hlt">twin</span> migration proceeds at a CRSS that is lower than the initiation stress ( Almost-Equal-To 114-153 MPa). The experimental results of the nucleation stresses indicate that the Schmid law holds to a first approximation for the slip and <span class="hlt">twin</span> nucleation cases, but to a lesser extent for <span class="hlt">twin</span> migration particularly when considerable slip strains preceded <span class="hlt">twinning</span>. The CRSSs were determined experimentally using digital image correlation (DIC) in conjunction with electron back scattering diffraction (EBSD). The DIC measurements enabled pinpointing the precise stress on the stress-strain curves where <span class="hlt">twins</span> or slip were activated. The crystal orientations were obtained using EBSD and used to determine the activated <span class="hlt">twin</span> and slip systems through trace analysis. - Highlights: Black-Right-Pointing-Pointer Digital image correlation allows to capture slip/<span class="hlt">twin</span> initiation for bcc FeCr. Black-Right-Pointing-Pointer Crystal orientations from EBSD allow slip/<span class="hlt">twin</span> system indexing. Black-Right-Pointing-Pointer Nucleation of slip always precedes <span class="hlt">twinning</span>. Black-Right-Pointing-Pointer <span class="hlt">Twin</span> growth is sustained with a lower stress than required for nucleation. Black-Right-Pointing-Pointer <span class="hlt">Twin</span>-slip interactions provide high hardening at the onset of plasticity.</p> <div class="credits"> <p class="dwt_author">Patriarca, L. [Politecnico di Milano, Department of Mechanical Engineering, Via La Masa 34, I-20156 Milano (Italy)] [Politecnico di Milano, Department of Mechanical Engineering, Via La Masa 34, I-20156 Milano (Italy); Abuzaid, Wael [Department of Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, 1206 W. Green St., Urbana, IL 61801 (United States)] [Department of Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, 1206 W. Green St., Urbana, IL 61801 (United States); Sehitoglu, Huseyin, E-mail: huseyin@illinois.edu [Department of Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, 1206 W. Green St., Urbana, IL 61801 (United States)] [Department of Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, 1206 W. Green St., Urbana, IL 61801 (United States); Maier, Hans J. [Lehrstuhl fuer Werkstoffkunde (Materials Science), University of Paderborn, 33095 Paderborn (Germany)] [Lehrstuhl fuer Werkstoffkunde (Materials Science), University of Paderborn, 33095 Paderborn (Germany); Chumlyakov, Y. [Physics of Plasticity and Strength of Materials Laboratory, Siberian Physical and Technical Institute, 634050 Tomsk (Russian Federation)] [Physics of Plasticity and Strength of Materials Laboratory, Siberian Physical and Technical Institute, 634050 Tomsk (Russian Federation)</p> <p class="dwt_publisher"></p> <p class="publishDate">2013-01-15</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">377</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://oaspub.epa.gov/eims/eimsapi.dispdetail?deid=43487"> <span id="translatedtitle">EVIDENCE FOR THE CHROMOSOMAL REPLICONS AS UNITS OF <span class="hlt">SISTER</span> CHROMATID EXCHANGES</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://oaspub.epa.gov/eims/query.page">EPA Science Inventory</a></p> <p class="result-summary">Current hypotheses of <span class="hlt">sister</span> chromatid exchange (SCE) formation postulate that sites of SCE induction are associated with active replicons or replicon clusters. We have applied the FCC-SCD technique to in vivo studies of mouse bone marrow cells that have been treated with cycloph...</p> <div class="credits"> <p class="dwt_author"></p> <p class="dwt_publisher"></p> <p class="publishDate"></p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">378</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://eric.ed.gov/?q=smb&id=ED503245"> <span id="translatedtitle">Making a Difference in Schools: The Big Brothers Big <span class="hlt">Sisters</span> School-Based Mentoring Impact Study</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p class="result-summary">School-based mentoring is one of the fastest growing forms of mentoring in the US today; yet, few studies have rigorously examined its impacts. This landmark random assignment impact study of Big Brothers Big <span class="hlt">Sisters</span> School-Based Mentoring is the first national study of this program model. It involves 10 agencies, 71 schools and 1,139 9- to…</p> <div class="credits"> <p class="dwt_author">Herrera, Carla; Grossman, Jean Baldwin; Kauh, Tina J.; Feldman, Amy F.; McMaken, Jennifer</p> <p class="dwt_publisher"></p> <p class="publishDate">2007-01-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">379</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://academic.research.microsoft.com/Publication/35774561"> <span id="translatedtitle">Vicia root-mirconucleus and <span class="hlt">sister</span> chromatid exchange assays on the genotoxicity of selenium compounds</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://academic.research.microsoft.com/">Microsoft Academic Search </a></p> <p class="result-summary">Selenium (Se) is an important metalloid with industrial, environmental, biological and toxicological significance. Excessive selenium in soil and water may contribute to environmental selenium pollution, and affect plant growth and human health. By using Vicia faba micronucleus (MN) and <span class="hlt">sister</span> chromatid exchange (SCE) tests, possible genotoxicity of sodium selenite and sodium biselenite was evaluated in this study. The results showed</p> <div class="credits"> <p class="dwt_author">Huilan Yi; Liangyan Si</p> <p class="dwt_publisher"></p> <p class="publishDate">2007-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">380</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://eric.ed.gov/?q=herrera&pg=7&id=EJ927867"> <span id="translatedtitle">Mentoring in Schools: An Impact Study of Big Brothers Big <span class="hlt">Sisters</span> School-Based Mentoring</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p class="result-summary">This random assignment impact study of Big Brothers Big <span class="hlt">Sisters</span> School-Based Mentoring involved 1,139 9- to 16-year-old students in 10 cities nationwide. Youth were randomly assigned to either a treatment group (receiving mentoring) or a control group (receiving no mentoring) and were followed for 1.5 school years. At the end of the first school…</p> <div class="credits"> <p class="dwt_author">Herrera, Carla; Grossman, Jean Baldwin; Kauh, Tina J.; McMaken, Jennifer</p> <p class="dwt_publisher"></p> <p class="publishDate">2011-01-01</p> </div> </div> </div> </div> <div id="filter_results_form" class="filter_results_form floatContainer" style="visibility: visible;"> <div style="width:100%" id="PaginatedNavigation" class="paginatedNavigationElement"> <a id="FirstPageLink" onclick='return showDiv("page_1");' href="#" title="First Page"> <img id="FirstPageLinkImage" class="Icon" src="http://www.science.gov/scigov/images/icon.first.18x20.png" alt="First Page" /></a> <a id="PreviousPageLink" onclick='return showDiv("page_18");' href="#" title="Previous Page"> <img id="PreviousPageLinkImage" class="Icon" src="http://www.science.gov/scigov/images/icon.previous.18x20.png" alt="Previous Page" /></a> <span id="PageLinks" class="pageLinks"> <span> <a onClick='return showDiv("page_1");' href="#">1</a> <a 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title="Next Page"> <img id="NextPageLinkImage" class="Icon" src="http://www.science.gov/scigov/images/icon.next.18x20.png" alt="Next Page" /></a> <a id="LastPageLink" onclick='return showDiv("page_25.0");' href="#" title="Last Page"> <img id="LastPageLinkImage" class="Icon" src="http://www.science.gov/scigov/images/icon.last.18x20.png" alt="Last Page" /></a> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">381</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://academic.research.microsoft.com/Publication/57880971"> <span id="translatedtitle">Black Women Writers and the Trouble with Ethos: Harriet Jacobs, Billie Holiday, and <span class="hlt">Sister</span> Souljah</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://academic.research.microsoft.com/">Microsoft Academic Search </a></p> <p class="result-summary">The assumption that black women lack a positive and respectable ethos is a historical and contemporary problem. To address the problem with ethos, I turn to Aristotle's Rhetoric to foreground an analysis of ethos. Then I examine Harriet Jacobs's slave narrative and the autobiography of Billie Holiday and <span class="hlt">Sister</span> Souljah, respectively, to illustrate the difficulty they faced as they attempted</p> <div class="credits"> <p class="dwt_author">Coretta Pittman</p> <p class="dwt_publisher"></p> <p class="publishDate">2006-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">382</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://volcanoes.usgs.gov/insar/public_files/AGU_2004_Sisters/Three_Sisters_Fall_2004_AGU7.pdf"> <span id="translatedtitle">An Ongoing Episode of Magmatic Inflation at the Three <span class="hlt">Sisters</span> Volcanic Center,</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.osti.gov/epsearch/">E-print Network</a></p> <p class="result-summary">, and Mount Bachelor At South <span class="hlt">Sister</span>, two eruptive sequences about 2200 and 2000 years ago produced rhyolite tephra, pyroclastic flows, lava flows, and lava domes Nearby, dominantly effusive eruptions of basaltic production rate in the entire Cascade arc Tens of vents spread over 400-km2 area have erupted in past 4000</p> <div class="credits"> <p class="dwt_author"></p> <p class="dwt_publisher"></p> <p class="publishDate"></p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">383</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://academic.research.microsoft.com/Publication/30589201"> <span id="translatedtitle">Macrocephaly, epilepsy, autism, dysmorphic features, and mental retardation in two <span class="hlt">sisters</span>: a new autosomal recessive syndrome?</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://academic.research.microsoft.com/">Microsoft Academic Search </a></p> <p class="result-summary">We report two <span class="hlt">sisters</span> with macrocephaly, epilepsy, and severe mental retardation. The first child was a 14 year old girl born at term after a normal pregnancy, with birth weight 3600 g and occipitofrontal circumference (OFC) 36 cm (75th centile). Her head size increased markedly during the first six months of life, and was later stable at 2-3 cm above</p> <div class="credits"> <p class="dwt_author">K H Orstavik; P Strømme; J Ek; A Torvik; O H Skjeldal</p> <p class="dwt_publisher"></p> <p class="publishDate">1997-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">384</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.ncbi.nlm.nih.gov/pubmed/9350820"> <span id="translatedtitle">Macrocephaly, epilepsy, autism, dysmorphic features, and mental retardation in two <span class="hlt">sisters</span>: a new autosomal recessive syndrome?</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p class="result-summary">We report two <span class="hlt">sisters</span> with macrocephaly, epilepsy, and severe mental retardation. The first child was a 14 year old girl born at term after a normal pregnancy, with birth weight 3600 g and occipitofrontal circumference (OFC) 36 cm (75th centile). Her head size increased markedly during the first six months of life, and was later stable at 2-3 cm above the 97.5th centile. Her development was characterised by psychomotor delay, epilepsy, and autistic features. Her face appeared mildly dysmorphic with a large forehead, short philtrum, and bushy eyebrows. Her younger <span class="hlt">sister</span> was also born at term with birth weight 2600 g and OFC 34 cm (25th centile). She also developed postnatal macrocephaly with OFC 2 cm above the 97.5th centile and the same mild dysmorphic facial features as her <span class="hlt">sister</span>. Her development was also characterised by psychomotor delay, autistic features, and epilepsy. In addition, she suffered from coeliac disease. She died unexpectedly at the age of 5 years, probably from an epileptic attack. Necropsy confirmed megalencephaly but no other pathological changes were found. The clinical features in these two <span class="hlt">sisters</span> do not fit with any known syndrome and may represent a previously unrecognised autosomal recessive disorder. PMID:9350820</p> <div class="credits"> <p class="dwt_author">Orstavik, K H; Strømme, P; Ek, J; Torvik, A; Skjeldal, O H</p> <p class="dwt_publisher"></p> <p class="publishDate">1997-10-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">385</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://eric.ed.gov/?q=islam+AND+in+AND+america&pg=3&id=EJ449479"> <span id="translatedtitle">The <span class="hlt">Sister</span> Clara Muhammad Schools: Pioneers in the Development of Islamic Education in America.</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p class="result-summary">Traces the history of <span class="hlt">Sister</span> Clara Muhammad schools from their beginnings in the early 1930s through their transformation into an orthodox Islamic educational system, and reviews the movement's role in the Council of Islamic Schools of North America. Muslim African Americans are increasingly identifying with the worldwide Islamic movement. (SLD)</p> <div class="credits"> <p class="dwt_author">Rashid, Hakim M.; Muhammad, Zakiyyah</p> <p class="dwt_publisher"></p> <p class="publishDate">1992-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">386</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://academic.research.microsoft.com/Publication/30536226"> <span id="translatedtitle">Retinitis pigmentosa, metaphyseal chondrodysplasia, and brachydactyly: an affected brother and <span class="hlt">sister</span></span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://academic.research.microsoft.com/">Microsoft Academic Search </a></p> <p class="result-summary">A brother and <span class="hlt">sister</span>, children of normal parents are described. They had retinitis pigmentosa, causing near-blindness as a result of very narrow fields of vision, associated with metaphyseal chondrodysplasia and marked shortening of the metacarpals and terminal phalanges. Autosomal recessive inheritance is suggested with a common biochemical cause for all these defects. This apparently new association of retinitis pigmentosa with</p> <div class="credits"> <p class="dwt_author">C I Phillips; R Wynne-Davies; N L Stokoe; M Newton</p> <p class="dwt_publisher"></p> <p class="publishDate">1981-01-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">387</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.aip.de/groups/sternphysik/stp/PDFFILES/2000/gaia_paper.pdf"> <span id="translatedtitle">Determination of Habitable Zones in Extrasolar Planetary Systems: Where are Gaia's <span class="hlt">Sisters</span>?</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.osti.gov/epsearch/">E-print Network</a></p> <p class="result-summary">).In other words, the search might have tracked down a <span class="hlt">sister</span> of "Gaia", i.e., a planet which sup- ports life scheme for assessing the suitability for life of extrasolar planets is pre- sented. The scheme focuses, biogeochemical, and geodynamic processes involved in the generation of photosynthesis-driven life conditions</p> <div class="credits"> <p class="dwt_author"></p> <p class="dwt_publisher"></p> <p class="publishDate"></p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">388</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://eric.ed.gov/?q=teenage+AND+pregnancy&pg=4&id=EJ965819"> <span id="translatedtitle">Youths' Caretaking of Their Adolescent <span class="hlt">Sisters</span>' Children: Its Costs and Benefits for Youths' Development</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p class="result-summary">This study examined how time spent caring for a teenage <span class="hlt">sister</span>'s child and experiences in providing care related to youths' young adult outcomes. Latino and African American youths (N = 108) were studied during middle and late adolescence. Results indicated that youths who provided many hours of child care were more stressed and had lower school…</p> <div class="credits"> <p class="dwt_author">East, Patricia L.; Weisner, Thomas S.; Reyes, Barbara T.</p> <p class="dwt_publisher"></p> <p class="publishDate">2006-01-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">389</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1050774"> <span id="translatedtitle">Two <span class="hlt">sisters</span> with a syndrome of ocular, skeletal, and abdominal abnormalities (OSA syndrome).</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p class="result-summary">Two adult <span class="hlt">sisters</span> are described who had a unique association of facial, ocular, and skeletal defects, and abdominal muscle hypoplasia, indicating autosomal recessive inheritance. Many of these features overlap those previously found in other malformation syndromes. However, the constellation of defects observed in these patients appears to represent a previously unreported syndrome and autosomal recessive inheritance is likely. Images PMID:8933348</p> <div class="credits"> <p class="dwt_author">Mingarelli, R; Castriota Scanderbeg, A; Dallapiccola, B</p> <p class="dwt_publisher"></p> <p class="publishDate">1996-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">390</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://eric.ed.gov/?q=incest&id=EJ1011495"> <span id="translatedtitle">Brother-<span class="hlt">Sister</span> Incest: Data from Anonymous Computer-Assisted Self Interviews</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p class="result-summary">Retrospective data were entered anonymously by 1,521 adult women using computer-assisted self interview. Forty were classified as victims of brother-<span class="hlt">sister</span> incest, 19 were classified as victims of father-daughter incest, and 232 were classified as victims of sexual abuse by an adult other than their father before reaching 18 years of age. The…</p> <div class="credits"> <p class="dwt_author">Stroebel, Sandra S.; O'Keefe, Stephen L.; Beard, Keith W.; Kuo, Shih-Ya; Swindell, Samuel; Stroupe, Walter</p> <p class="dwt_publisher"></p> <p class="publishDate">2013-01-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">391</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://files.eric.ed.gov/fulltext/EJ1006061.pdf"> <span id="translatedtitle">Catherine Spalding: Co-Foundress of the <span class="hlt">Sisters</span> of Charity of Nazareth</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p class="result-summary">The <span class="hlt">Sisters</span> of Charity of Nazareth (SCN) maintain a vibrant presence in ministry in the US. This article presents an overview of their co-foundress, Catherine Spalding, and shows Mother Catherine to be the creative, mission-driven, and articulate leader that is still very much in need in today's society.</p> <div class="credits"> <p class="dwt_author">Shaughnessy, Mary Angela</p> <p class="dwt_publisher"></p> <p class="publishDate">2006-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">392</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4066400"> <span id="translatedtitle">Tension-dependent removal of pericentromeric shugoshin is an indicator of <span class="hlt">sister</span> chromosome biorientation</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p class="result-summary">During mitosis and meiosis, <span class="hlt">sister</span> chromatid cohesion resists the pulling forces of microtubules, enabling the generation of tension at kinetochores upon chromosome biorientation. How tension is read to signal the bioriented state remains unclear. Shugoshins form a pericentromeric platform that integrates multiple functions to ensure proper chromosome biorientation. Here we show that budding yeast shugoshin Sgo1 dissociates from the pericentromere reversibly in response to tension. The antagonistic activities of the kinetochore-associated Bub1 kinase and the Sgo1-bound phosphatase protein phosphatase 2A (PP2A)-Rts1 underlie a tension-dependent circuitry that enables Sgo1 removal upon <span class="hlt">sister</span> kinetochore biorientation. Sgo1 dissociation from the pericentromere triggers dissociation of condensin and Aurora B from the centromere, thereby stabilizing the bioriented state. Conversely, forcing <span class="hlt">sister</span> kinetochores to be under tension during meiosis I leads to premature Sgo1 removal and precocious loss of pericentromeric cohesion. Overall, we show that the pivotal role of shugoshin is to build a platform at the pericentromere that attracts activities that respond to the absence of tension between <span class="hlt">sister</span> kinetochores. Disassembly of this platform in response to intersister kinetochore tension signals the bioriented state. Therefore, tension sensing by shugoshin is a central mechanism by which the bioriented state is read. PMID:24939933</p> <div class="credits"> <p class="dwt_author">Nerusheva, Olga O.; Galander, Stefan; Fernius, Josefin; Kelly, David; Marston, Adele L.</p> <p class="dwt_publisher"></p> <p class="publishDate">2014-01-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">393</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://eric.ed.gov/?q=sibling+AND+relationships&pg=3&id=EJ818749"> <span id="translatedtitle">Improving Emotion Regulation and Sibling Relationship Quality: The More Fun with <span class="hlt">Sisters</span> and Brothers Program</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p class="result-summary">We examined the role of emotion regulation (ER) in improving sibling relationship quality (SRQ) by evaluating the More Fun With <span class="hlt">Sisters</span> and Brothers Program where 4- to 8-year-old siblings from 95 families were taught emotional and social competencies. Parents reported on SRQ and ER, and sibling interactions were observed in homes. SRQ and ER…</p> <div class="credits"> <p class="dwt_author">Kennedy, Denise E.; Kramer, Laurie</p> <p class="dwt_publisher"></p> <p class="publishDate">2008-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">394</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.sfu.ca/biology/faculty/crespi/pdfs/118-CrespiSummersDorus2009inpress.pdf"> <span id="translatedtitle">Evolutionary Applications (in press, December 2008) Genomic <span class="hlt">Sister</span>-Disorders of Neurodevelopment</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.osti.gov/epsearch/">E-print Network</a></p> <p class="result-summary">-Magenis syndrome, as well as the X-chromosomal conditions Klinefelter and Turner syndromes. These data suggest of protein-coding genes, or selective sweeps, for three of the four sets of <span class="hlt">sister</span>-syndromes analyzed. Keywords: gene copy-number variation, schizophrenia, autism, evolution, positive Darwinian selection #12</p> <div class="credits"> <p class="dwt_author">Crespi, Bernard J.</p> <p class="dwt_publisher"></p> <p class="publishDate"></p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">395</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://academic.research.microsoft.com/Publication/44602346"> <span id="translatedtitle">Moms, <span class="hlt">Sisters</span>, and LadiesWomen Student Trainers in Men's Intercollegiate Sport</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://academic.research.microsoft.com/">Microsoft Academic Search </a></p> <p class="result-summary">This study presents accounts of nine women student athletic trainers (SATs) working as interns in an athletic program at a large university. The presence of women within a historically closed masculine sport environment was resolved by viewing the women within the traditionally feminine roles of “mom,”“<span class="hlt">sister</span>,” and “lady.” Subject to overt and subtle discrimination, sexist and misogynist behavior, as well</p> <div class="credits"> <p class="dwt_author">STEPHAN R. Walk</p> <p class="dwt_publisher"></p> <p class="publishDate">1999-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">396</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.gpo.gov:80/fdsys/pkg/CFR-2014-title40-vol17/pdf/CFR-2014-title40-vol17-sec79-65.pdf"> <span id="translatedtitle">40 CFR 79.65 - In vivo <span class="hlt">sister</span> chromatid exchange assay.</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href=""></a></p> <p class="result-summary">...of a chemical to enhance the exchange of DNA between two <span class="hlt">sister</span> chromatids of a duplicating...translocation and ligation of at least two DNA helices. (c) Test method —(1...considered not to induce rearrangements of DNA segments in this system. (iii)...</p> <div class="credits"> <p class="dwt_author"></p> <p class="dwt_publisher"></p> <p class="publishDate">2014-07-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">397</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://academic.research.microsoft.com/Publication/16533261"> <span id="translatedtitle">Comparison of <span class="hlt">sister</span> chromatid exchange frequency in peripheral lymphocytes in lung cancer cases and controls</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://academic.research.microsoft.com/">Microsoft Academic Search </a></p> <p class="result-summary">Cytogenetic alterations have been associated with the occurrence of many cancers. However, limited data exist to address whether increased chromosomal changes in surrogate normal tissue are similarly associated with malignancy. As part of an ongoing case-control study of lung cancer, we have studied the factors that affect <span class="hlt">sister</span> chromatid exchange (SCE) frequency in lymphocytes from lung cancer patients. Further, we</p> <div class="credits"> <p class="dwt_author">Tsun-Jen Cheng; David C. Christiani; John K. Wiencke; John C. WainXiping Xu; Karl T. Kelsey</p> <p class="dwt_publisher"></p> <p class="publishDate">1995-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">398</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://files.eric.ed.gov/fulltext/ED205747.pdf"> <span id="translatedtitle">Variations in the Educational and Career Development Paths of Brothers and <span class="hlt">Sisters</span>.</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p class="result-summary">A study examined the extent to which socioeconomic and internal characteristics of families differentially affect ability of matched pairs of brothers and <span class="hlt">sisters</span> to progress through the educational system. The data sets used were the National Longitudinal Surveys of Work Experience of Young Men and Women who were originally interviewed in 1966…</p> <div class="credits"> <p class="dwt_author">Mott, Frank L.; Haurin, R. Jean</p> <p class="dwt_publisher"></p> <p class="publishDate"></p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">399</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://academic.research.microsoft.com/Publication/39173610"> <span id="translatedtitle"><span class="hlt">Sister</span> Joseph's nodule in a liver transplant recipient: Case report and mini-review of literature</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://academic.research.microsoft.com/">Microsoft Academic Search </a></p> <p class="result-summary">BACKGROUND: Umbilical metastasis is one of the main characteristic signs of extensive neoplastic disease and is universally referred to as <span class="hlt">Sister</span> Mary Joseph's nodule. CASE PRESENTATION: A 59-years-old Caucasian female underwent liver transplant for end stage liver disease due to hepatitis C with whole graft from cadaveric donor in 2003. After transplantation the patient developed multiple subcutaneous nodules in the</p> <div class="credits"> <p class="dwt_author">Fabrizio Panaro; Enzo Andorno; Stefano Di Domenico; Nicola Morelli; Giuliano Bottino; Rosalia Mondello; Marco Miggino; Tomasz M Jarzembowski; Ferruccio Ravazzoni; Marco Casaccia; Umberto Valente</p> <p class="dwt_publisher"></p> <p class="publishDate">2005-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">400</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://academic.research.microsoft.com/Publication/14806139"> <span id="translatedtitle">Cytological detection of mutagen-carcinogen exposure by <span class="hlt">sister</span> chromatid exchange</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://academic.research.microsoft.com/">Microsoft Academic Search </a></p> <p class="result-summary">A staining technique that detects <span class="hlt">sister</span> chromatid exchanges (SCEs) has been used to examine the response of chromosomes in cultured Chinese hamster cells to a wide variety of mutagens-carcinogens. The test gives a very sensitive and rapid method for detecting chromosome mutagenicity of chemical agents and provides a powerful new method for detecting environmental mutagens.</p> <div class="credits"> <p class="dwt_author">P. Perry; H. J. Evans</p> <p class="dwt_publisher"></p> <p class="publishDate">1975-01-01</p> </div> </div> </div> </div> <div id="filter_results_form" class="filter_results_form floatContainer" style="visibility: visible;"> <div style="width:100%" id="PaginatedNavigation" class="paginatedNavigationElement"> <a id="FirstPageLink" onclick='return showDiv("page_1");' href="#" title="First Page"> <img id="FirstPageLinkImage" class="Icon" src="http://www.science.gov/scigov/images/icon.first.18x20.png" alt="First Page" /></a> <a id="PreviousPageLink" onclick='return showDiv("page_19");' href="#" title="Previous Page"> <img id="PreviousPageLinkImage" class="Icon" src="http://www.science.gov/scigov/images/icon.previous.18x20.png" alt="Previous Page" /></a> <span id="PageLinks" class="pageLinks"> <span> <a onClick='return showDiv("page_1");' href="#">1</a> <a onClick='return showDiv("page_2");' href="#">2</a> <a onClick='return showDiv("page_3");' href="#">3</a> <a onClick='return showDiv("page_4");' 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onclick='return showDiv("page_25.0");' href="#" title="Last Page"> <img id="LastPageLinkImage" class="Icon" src="http://www.science.gov/scigov/images/icon.last.18x20.png" alt="Last Page" /></a> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">401</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://eric.ed.gov/?q=aesthetic&id=EJ1003992"> <span id="translatedtitle">Empirical Psycho-Aesthetics and Her <span class="hlt">Sisters</span>: Substantive and Methodological Issues--Part II</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p class="result-summary">Empirical psycho-aesthetics is approached in this two-part article from two directions. Part I, which appeared in the Winter 2012 issue of "JAE," addressed definitional and organizational issues, including the field's origins, its relation to "<span class="hlt">sister</span>" disciplines (experimental philosophy, cognitive neuroscience of art, and neuroaesthetics), and…</p> <div class="credits"> <p class="dwt_author">Konecni, Vladimir J.</p> <p class="dwt_publisher"></p> <p class="publishDate">2013-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">402</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.plantcell.org/cgi/rapidpdf/tpc.106.041111v1.pdf"> <span id="translatedtitle">Independent Ancient Polyploidy Events in the <span class="hlt">Sister</span> Families Brassicaceae and Cleomaceae</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://academic.research.microsoft.com/">Microsoft Academic Search </a></p> <p class="result-summary">Recent studies have elucidated the ancient polyploid history of the Arabidopsis thaliana (Brassicaceae) genome. The studies concur that there was at least one polyploidy event occurring some 14.5 to 86 million years ago (Mya), possibly near the divergence of the Brassicaceae from its <span class="hlt">sister</span> family, Cleomaceae. Using a comparative genomics approach, we asked whether this polyploidy event was unique to</p> <div class="credits"> <p class="dwt_author">M. Eric Schranz; Thomas Mitchell-Olds</p> <p class="dwt_publisher"></p> <p class="publishDate"></p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">403</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://eric.ed.gov/?q=%22moral+enhancement%22&id=EJ755531"> <span id="translatedtitle">Meanings of Sisterhood and Developmental Disability: Narratives from White Nondisabled <span class="hlt">Sisters</span></span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p class="result-summary">Integrating thought from critical feminist and disability theorists via a strategic social constructionist perspective, the authors analyzed 10 in-depth qualitative interviews to begin to understand the dialogue between (a) how nondisabled <span class="hlt">sisters</span> understand themselves and their siblings with developmental disabilities and (b) wider systems of…</p> <div class="credits"> <p class="dwt_author">McGraw, Lori A.; Walker, Alexis J.</p> <p class="dwt_publisher"></p> <p class="publishDate">2007-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">404</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://eric.ed.gov/?q=treatment+AND+for+AND+alcoholism&pg=2&id=EJ406575"> <span id="translatedtitle">Characteristics of Alcoholism among Catholic <span class="hlt">Sisters</span>: Results of a National Survey.</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p class="result-summary">Obtained information on addiction history, intervention and treatment, and family and community patterns from 221 Catholic <span class="hlt">Sisters</span> in residential treatment for alcoholism. Findings suggest that, although respondents were similar to other women in their vulnerability to addiction, they carried added burdens because of societal expectations of…</p> <div class="credits"> <p class="dwt_author">Spiegel, Virginia M.</p> <p class="dwt_publisher"></p> <p class="publishDate">1989-01-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">405</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://eric.ed.gov/?q=ideology&pg=3&id=EJ997719"> <span id="translatedtitle">A Tale of Three <span class="hlt">Sisters</span>: Language Ideologies, Identities, and Negotiations in a Bilingual, Transnational Family</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p class="result-summary">This longitudinal case study investigated how linguistic identity was constructed, constrained, and performed by three <span class="hlt">sisters</span>, aged 1, 12, and 17, within one bilingual, transnational Ecuadorian-U.S. family. Data were collected over 14 months through weekly home visits that included participant observation, informal interviews, and…</p> <div class="credits"> <p class="dwt_author">King, Kendall A.</p> <p class="dwt_publisher"></p> <p class="publishDate">2013-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">406</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://academic.research.microsoft.com/Publication/10279430"> <span id="translatedtitle"><span class="hlt">Twinning</span> and detwinning of ?0?1?1? type II <span class="hlt">twin</span> in shape memory alloy</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://academic.research.microsoft.com/">Microsoft Academic Search </a></p> <p class="result-summary">?0?1?1? type II <span class="hlt">twin</span> is a major <span class="hlt">twinning</span> mode frequently observed in NiTi shape memory alloy. Its response to applied stresses is responsible for various inelastic deformation processes. In order to predict the shape recovery characteristic under various conditions, it is of primary importance to predict the martensite detwinning characteristic prior to the reverse transformation. However, due to its irrational</p> <div class="credits"> <p class="dwt_author">Yong Liu; Z. L. Xie</p> <p class="dwt_publisher"></p> <p class="publishDate">2003-01-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">407</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.springerlink.com/index/v1407016814207p4.pdf"> <span id="translatedtitle">Prognosis and long-term neurodevelopmental outcome in conservatively treated <span class="hlt">twin-to-twin</span> transfusion syndrome</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://academic.research.microsoft.com/">Microsoft Academic Search </a></p> <p class="result-summary">Background  Amnioreduction remains a treatment option for pregnancies with <span class="hlt">twin-to-twin</span> transfusion syndrome (TTTS) not meeting criteria\\u000a for laser surgery or those in which it is not feasible. Amnioreduction is a relatively simple treatment which does not require\\u000a sophisticated technical equipment. Previous reports of conservative management have indicated that major neurodevelopmental\\u000a impairment occurs in 14.3-26% of survivors. The purpose of this study</p> <div class="credits"> <p class="dwt_author">Xiangqun Li; Seiichi Morokuma; Kotaro Fukushima; Yuka Otera; Yasuo Yumoto; Kiyomi Tsukimori; Masayuki Ochiai; Toshiro Hara; Norio Wake</p> <p class="dwt_publisher"></p> <p class="publishDate">2011-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">408</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://eric.ed.gov/?q=flight&pg=7&id=EJ963861"> <span id="translatedtitle"><span class="hlt">Twin</span> Paradox in de Sitter Spacetime</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p class="result-summary">The "<span class="hlt">twin</span> paradox" of special relativity offers the possibility of making interstellar flights within a lifetime. For very long journeys with velocities close to the speed of light, however, we have to take into account the expansion of the universe. Inspired by the work of Rindler on hyperbolic motion in curved spacetime, we study the worldline…</p> <div class="credits"> <p class="dwt_author">Boblest, Sebastian; Muller, Thomas; Wunner, Gunter</p> <p class="dwt_publisher"></p> <p class="publishDate">2011-01-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">409</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://files.eric.ed.gov/fulltext/ED299653.pdf"> <span id="translatedtitle">Referential Communication Skills in <span class="hlt">Twin</span> Children.</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p class="result-summary">Some researchers have stressed the negative effects of the peculiar interactive situation of <span class="hlt">twins</span> on the development of communicative competence; other researchers have shown early positive effects. Referential communication--one of the most evolved, intellectualized, and decentered functions of language that consists of transmitting information…</p> <div class="credits"> <p class="dwt_author">Carelli, Maria Grazia; Benelli, B.</p> <p class="dwt_publisher"></p> <p class="publishDate"></p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">410</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://ntrs.nasa.gov/search.jsp?R=19840010805&hterms=frog&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D80%26Ntt%3Dfrog"> <span id="translatedtitle"><span class="hlt">Twinning</span> of amphibian embryos by centrifugation</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p class="result-summary">In the frog Xenopus laevis, the dorsal structures of the embryonic body axis normally derive from the side of the egg opposite the side of sperm entry. However, if the uncleaved egg is inclined at lg or centrifuged in an inclined position, this topographic relationship is overridden: the egg makes its dorsal axial structures according to its orientation in the gravitational/centrifugal field, irrespective of the position of sperm entry. Certain conditions of centrifugation cause eggs to develop into conjoined <span class="hlt">twins</span> with two sets of axial structures. A detailed analysis of <span class="hlt">twinning</span> provided some insight into experimental axis orientation. First, as with single-axis embryos, both axes in <span class="hlt">twins</span> are oriented according to the direction of centrifugation. One axis forms at the centripetal side of the egg and the other forms at the centrifugal side, even when the side of sperm entry is normal to the centrifugal force vector. Second, if eggs are centrifuged to give <span class="hlt">twins</span>, but are inclined at lg to prevent post-centrifugation endoplasmic redistributions, only single-axis embryos develop. Thus, a second redistribution is required for high-frequency secondary axis formation. This can be accomplished by lg (as in the single centrifugations) or by a second centrifugation directed along the egg's animal-vegetal axis.</p> <div class="credits"> <p class="dwt_author">Black, S. D.</p> <p class="dwt_publisher"></p> <p class="publishDate">1984-01-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">411</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.catalogs.umn.edu/download/TCgrad/GradEdCat-Fall2012-CSOM.pdf"> <span id="translatedtitle"><span class="hlt">Twin</span> Cities Campus Accountancy M.Acc.</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.osti.gov/epsearch/">E-print Network</a></p> <p class="result-summary">· · · · · · <span class="hlt">Twin</span> Cities Campus Accountancy M.Acc. Accounting Curtis L. Carlson School of Management that apply to all major fields. The M.Acc. program offers students a one-year program with a broad selection and developed by Carlson School faculty with extensive input and ongoing consultation with executives from</p> <div class="credits"> <p class="dwt_author">Blanchette, Robert A.</p> <p class="dwt_publisher"></p> <p class="publishDate"></p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">412</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.catalogs.umn.edu/download/TCgrad/GradEdCat-Fall2012-CCE.pdf"> <span id="translatedtitle"><span class="hlt">Twin</span> Cities Campus Addiction Studies Postbaccalaureate Certificate</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.osti.gov/epsearch/">E-print Network</a></p> <p class="result-summary">· · · · · · · <span class="hlt">Twin</span> Cities Campus Addiction Studies Postbaccalaureate Certificate CCE Addiction: Addiction Studies, Degree and Certificate Programs, 20 Ruttan Hall, 1994 Buford Avenue, St. Paul, MN 55108 (612-624-4000; fax: 612- 625-1511) Email: cceinfo@umn.edu Website: http://www.cce.umn.edu/Addiction</p> <div class="credits"> <p class="dwt_author">Blanchette, Robert A.</p> <p class="dwt_publisher"></p> <p class="publishDate"></p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">413</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://academic.research.microsoft.com/Publication/28631266"> <span id="translatedtitle">Case report: a black and white <span class="hlt">twin</span></span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://academic.research.microsoft.com/">Microsoft Academic Search </a></p> <p class="result-summary">Albinism is an autosomal recessive disorder that is caused by a defective synthesis of melanin, resulting in a generalized reduction of pigmentation in the skin, hair and eyes, and leading to an increased risk of skin cancer and vision problems. We report a case of a 22-year-old primigravida of Negroid origin who delivered dichorial diamniotic <span class="hlt">twins</span>: two daughters were born</p> <div class="credits"> <p class="dwt_author">M J Claas; A Timmermans; H W Bruinse</p> <p class="dwt_publisher"></p> <p class="publishDate">2010-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">414</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.ncbi.nlm.nih.gov/pubmed/17635691"> <span id="translatedtitle"><span class="hlt">Twin</span> troubles--rickets causing myelofibrosis.</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p class="result-summary">Myelofibrosis is an uncommon condition that causes anaemia, failure to thrive and massive splenomegaly. This case report describes migrant Sudanese <span class="hlt">twins</span> who developed myelofibrosis secondary to severe rickets from a combination of poor diet, inadequate sun exposure, and a breastfeeding mother who wore hijab and was also vitamin D deficient. PMID:17635691</p> <div class="credits"> <p class="dwt_author">Kamien, Benjamin; Harris, Linda</p> <p class="dwt_publisher"></p> <p class="publishDate">2007-01-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">415</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.cdc.gov/nceh/ehs/Docs/APC/APC_Food_Safety_Self_Inspection_Checklist.pdf"> <span id="translatedtitle"><span class="hlt">Twin</span> Cities Metro Advanced Practice Center</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.osti.gov/epsearch/">E-print Network</a></p> <p class="result-summary">contact with ready-to-eat and ready-to­serve foods. 8. Supply adequate hand-washing facilities and hand contamination. 14. Cleaned & sanitize all food preparation areas. 15. Segregate or discard damaged food<span class="hlt">Twin</span> Cities Metro Advanced Practice Center Food Safety Self Inspection Checklist #12;Table</p> <div class="credits"> <p class="dwt_author"></p> <p class="dwt_publisher"></p> <p class="publishDate"></p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">416</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://eric.ed.gov/?q=brain+AND+hemisphere+AND+sex&pg=3&id=EJ950022"> <span id="translatedtitle">A Pediatric <span class="hlt">Twin</span> Study of Brain Morphometry</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p class="result-summary">Background: Longitudinal pediatric neuroimaging studies have demonstrated increasing volumes of white matter and regionally-specific inverted U shaped developmental trajectories of gray matter volumes during childhood and adolescence. Studies of monozygotic and dyzygotic <span class="hlt">twins</span> during this developmental period allow exploration of genetic and…</p> <div class="credits"> <p class="dwt_author">Wallace, Gregory L.; Schmitt, J. Eric; Lenroot, Rhoshel; Viding, Essi; Ordaz, Sarah; Rosenthal, Michael A.; Molloy, Elizabeth A.; Clasen, Liv S.; Kendler, Kenneth S.; Neale, Michael C.; Giedd, Jay N.</p> <p class="dwt_publisher"></p> <p class="publishDate">2006-01-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">417</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://academic.research.microsoft.com/Publication/36923588"> <span id="translatedtitle"><span class="hlt">Twin</span> Similarity in Cardiovascular Stress Response</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://academic.research.microsoft.com/">Microsoft Academic Search </a></p> <p class="result-summary">Cardiovascular (CV) responses to laboratory stressors were measured in 12 pairs of identical and 21 pairs of fraternal adult male <span class="hlt">twins</span>. For this study, blood pressure and heart rate were measured during a mental arithmetic task and the Cold Pressor Test. The analyses of cardiovascular responses to these stressors were designed to test for the presence of a genetic component</p> <div class="credits"> <p class="dwt_author">Dorit Carmelli; Margaret A. Chesney; Marcia M. Ward; Ray H. Rosenman</p> <p class="dwt_publisher"></p> <p class="publishDate">1985-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">418</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.springerlink.com/index/k407322417234432.pdf"> <span id="translatedtitle">Nanoparticle Charging in a <span class="hlt">Twin</span> Hewitt Charger</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://academic.research.microsoft.com/">Microsoft Academic Search </a></p> <p class="result-summary">A new unipolar charger for aerosol nanoparticles has been developed. In this <span class="hlt">twin</span> Hewitt charger two corona discharge zones are connected by a charging zone where the nanoparticle aerosol flows. Ions move into the charging zone alternating from each corona discharging zone by means of a square-wave voltage. The operation parameters of the device have been experimentally investigated at standard</p> <div class="credits"> <p class="dwt_author">F. E. Kruis; H. Fissan</p> <p class="dwt_publisher"></p> <p class="publishDate">2001-01-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">419</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3900763"> <span id="translatedtitle">An overview of human handedness in <span class="hlt">twins</span></span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p class="result-summary">There has been a long-standing debate on the complex correlation between the development of human hand preference and brain lateralization. Handedness, used as a proxy for cerebral lateralization, is a topic of considerable importance because of its potential to reveal the mechanisms of the underlying pathophysiology of problems related to brain development or cognitive systems. <span class="hlt">Twin</span> studies, which represent an important method of research in human genetics, would provide valuable suggestions to the studies on the relationship between lateralization and cognitive systems. Many studies have been performed using <span class="hlt">twin</span> subjects; however, the results are inconsistent, partly because of sample size, background assumptions, data limits or inaccuracies, incorrect zygosity classification, and/or lack of birth histories. In summary, within the long history and large number of <span class="hlt">twin</span> studies performed on handedness, a surprisingly large number of controversial findings have been reported, suggesting the complicated nature of this phenotype. In this mini review, the wide variety of <span class="hlt">twin</span> studies on human handedness performed to date are introduced. PMID:24478742</p> <div class="credits"> <p class="dwt_author">Ooki, Syuichi</p> <p class="dwt_publisher"></p> <p class="publishDate">2014-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">420</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://academic.research.microsoft.com/Publication/30210944"> <span id="translatedtitle">Munchausen syndrome by proxy in <span class="hlt">twins</span></span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://academic.research.microsoft.com/">Microsoft Academic Search </a></p> <p class="result-summary">A family is described in which <span class="hlt">twin</span> infants had repeated admissions for apparent haemoptysis. It was proved that the mother was simulating these episodes and she eventually injured one of the children with a pin. The mother has subsequently shown some evidence of a Munchausen tendency in herself.</p> <div class="credits"> <p class="dwt_author">D A Lee</p> <p class="dwt_publisher"></p> <p class="publishDate">1979-01-01</p> </div> </div> </div> </div> <div id="filter_results_form" class="filter_results_form floatContainer" style="visibility: visible;"> <div style="width:100%" id="PaginatedNavigation" class="paginatedNavigationElement"> <a id="FirstPageLink" onclick='return showDiv("page_1");' href="#" title="First Page"> <img id="FirstPageLinkImage" class="Icon" src="http://www.science.gov/scigov/images/icon.first.18x20.png" alt="First Page" /></a> <a id="PreviousPageLink" onclick='return showDiv("page_20");' href="#" title="Previous Page"> <img id="PreviousPageLinkImage" class="Icon" src="http://www.science.gov/scigov/images/icon.previous.18x20.png" alt="Previous Page" /></a> <span id="PageLinks" class="pageLinks"> <span> <a onClick='return showDiv("page_1");' href="#">1</a> <a onClick='return 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title="Next Page"> <img id="NextPageLinkImage" class="Icon" src="http://www.science.gov/scigov/images/icon.next.18x20.png" alt="Next Page" /></a> <a id="LastPageLink" onclick='return showDiv("page_25.0");' href="#" title="Last Page"> <img id="LastPageLinkImage" class="Icon" src="http://www.science.gov/scigov/images/icon.last.18x20.png" alt="Last Page" /></a> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">421</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.springerlink.com/index/p7313418u5320360.pdf"> <span id="translatedtitle">Creative abilities in identical and fraternal <span class="hlt">twins</span></span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://academic.research.microsoft.com/">Microsoft Academic Search </a></p> <p class="result-summary">The present research set out to investigate the possibility of a genetic component in creative ability The pool of subjects for this study consisted of 117 pairs of <span class="hlt">twins</span>, 13–19 years of age, divided into 28 pairs of identical males, 19 pairs of fraternal males, 35 pairs of identical females, and 35 pairs of fraternal females. A battery of ten</p> <div class="credits"> <p class="dwt_author">Marvin Reznikoff; George Domino; Carolyn Bridges; Merton Honeyman</p> <p class="dwt_publisher"></p> <p class="publishDate">1973-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">422</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://adsabs.harvard.edu/abs/2014JAP...116q4303X"> <span id="translatedtitle"><span class="hlt">Twinning</span> effect on photoluminescence spectra of ZnSe nanowires</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p class="result-summary">Bandgap engineering in a single material along the axial length of nanowires may be realized by arranging periodic <span class="hlt">twinning</span>, whose <span class="hlt">twin</span> plane is vertical to the axial length of nanowires. In this paper, we report the effect of <span class="hlt">twin</span> on photoluminescence of ZnSe nanowires, which refers to the bandgap of it. The exciton-related emission peaks of transverse <span class="hlt">twinning</span> ZnSe nanowires manifest a 10-meV-blue-shift in comparison with those of longitudinal <span class="hlt">twinning</span> ZnSe nanowires. The blue-shift is attributed to quantum confinement effect, which is influenced severely by the proportion of wurtzite ZnSe layers in ZnSe nanowires.</p> <div class="credits"> <p class="dwt_author">Xu, Jing; Wang, Chunrui; Wu, Binhe; Xu, Xiaofeng; Chen, Xiaoshuang; Oh, Hongseok; Baek, Hyeonjun; Yi, Gyu-Chul</p> <p class="dwt_publisher"></p> <p class="publishDate">2014-11-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">423</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://ntrs.nasa.gov/search.jsp?R=PIA06322&hterms=discovered+molecules&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D40%26Ntt%3Ddiscovered%2Bmolecules"> <span id="translatedtitle">Morphology of Our Galaxy's '<span class="hlt">Twin</span>'</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p class="result-summary"><p/> NASA's Spitzer Space Telescope has captured these infrared images of a nearby spiral galaxy that resembles our own Milky Way. The targeted galaxy, known as NGC 7331 and sometimes referred to as our galaxy's <span class="hlt">twin</span>, is found in the constellation Pegasus at a distance of 50 million light-years. This inclined galaxy was discovered in 1784 by William Herschel, who also discovered infrared light. <p/> The evolution of this galaxy is a story that depends significantly on the amount and distribution of gas and dust, the locations and rates of star formation, and on how the energy from star formation is recycled by the local environment. The new Spitzer images are allowing astronomers to 'read' this story by dissecting the galaxy into its separate components. <p/> The image, measuring 12.6 by 8.2 arcminutes, was obtained by Spitzer's infrared array camera. It is a four-color composite of invisible light, showing emissions from wavelengths of 3.6 microns (blue), 4.5 microns (green), 5.8 microns (yellow) and 8.0 microns (red). These wavelengths are roughly 10 times longer than those seen by the human eye. <p/> The infrared light seen in this image originates from two very different sources. At shorter wavelengths (3.6 to 4.5 microns), the light comes mainly from stars, particularly ones that are older and cooler than our Sun. This starlight fades at longer wavelengths (5.8 to 8.0 microns), where instead we see the glow from clouds of interstellar dust. This dust consists mainly of a variety of carbon-based organic molecules known collectively as polycyclic aromatic hydrocarbons. Wherever these compounds are found, there will also be dust granules and gas, which provide a reservoir of raw materials for future star formation. <p/> One feature that stands out in the Spitzer image is the ring of actively forming stars that surrounds the galaxy center (yellow). This ring, with a radius of nearly 20,000 light-years, is invisible at shorter wavelengths, yet has been detected at sub-millimeter and radio wavelengths. It is made up in large part of polycyclic aromatic hydrocarbons. Spitzer measurements suggest that the ring contains enough gas to produce four billion stars like the Sun. <p/> Three other galaxies are seen below NGC 7331, all about 10 times farther away. From left to right are NGC 7336, NGC 7335 and NGC 7337. The blue dots scattered throughout the images are foreground stars in the Milky Way; the red ones are galaxies that are even more distant. <p/> The Spitzer observations of NGC 7331 are part of a large 500-hour science project, known as the Spitzer Infrared Nearby Galaxy Survey, which will comprehensively study 75 nearby galaxies with infrared imaging and spectroscopy. <p/></p> <div class="credits"> <p class="dwt_author"></p> <p class="dwt_publisher"></p> <p class="publishDate">2004-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">424</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://adsabs.harvard.edu/abs/2013APS..MARM46006L"> <span id="translatedtitle">Reflectance spectrometry of placental vessels in cases of <span class="hlt">twin-twin</span> transfusion syndrome: experiments and modeling</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p class="result-summary">A stochastic photon transport model in multilayer skin tissue combined with reflectance spectroscopy measurements is used to study placental vessels in cases of <span class="hlt">twin-twin</span> transfusion syndrome (TTTS). TTTS occurs in about 12% of monozygotic (identical) <span class="hlt">twin</span> pregnancies wherein flow within placental vessels linking the <span class="hlt">twins</span> together becomes unbalanced, leading to dual mortality. Endoscopic laser ablation can halt the syndrome by occluding the anastomoses connecting the two fetuses. The objective of this study is to develop a technique to determine hemoglobin (Hb) content through spectral analysis of diffuse reflectance spectra of placental vessels to aid in identification of the anastomoses. Previous work by researchers at Brown University has shown that the reflectance spectra of the donor <span class="hlt">twin</span> and recipient <span class="hlt">twin</span> are considerably different in the wavelengths for Hb absorbance. This presentation will give preliminary results for a Monte Carlo model adapted to fit the physiology of the placenta that can be used to quantitative determine the Hb levels. The reflectance spectra of the vessels are simulated for different values of Hb as well oxygenation and water concentration with the vessel and placental mass. The preliminary results will be shown to be in good approximation with the prior experimental data. The combination of modeling with spectroscopic measurement will provide a new tool for detailed prenatal study.</p> <div class="credits"> <p class="dwt_author">Lines, Collin; Kim, Oleg; McMurdy, John; Luks, Francois; Alber, Mark; Crawford, Greg</p> <p class="dwt_publisher"></p> <p class="publishDate">2013-03-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">425</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.ncbi.nlm.nih.gov/pubmed/24210176"> <span id="translatedtitle">Are there <span class="hlt">healthy</span> obese?</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p class="result-summary">It is currently postulated that not all obese individuals have to be considered as pathological subjects. From 10% to 20% of obese people studied do not show the metabolic changes common in obese patients. The term "<span class="hlt">healthy</span> obese" has been coined to refer to these patients and differentiate them from the larger and more common group of pathological obese subjects. However, the definition of "<span class="hlt">healthy</span> obese" is not clear. Use of "<span class="hlt">healthy</span> obese" as a synonym for obese without metabolic complications is risky. Clinical markers such as insulin resistance are used to identify this pathology. It is not clear that <span class="hlt">healthy</span> obese subjects have lower morbidity and mortality than pathologically obese patients. According to some authors, <span class="hlt">healthy</span> obese would represent an early stage in evolution towards pathological obesity. There is no agreement as to the need to treat <span class="hlt">healthy</span> obese subjects. PMID:24210176</p> <div class="credits"> <p class="dwt_author">Griera Borrás, José Luis; Contreras Gilbert, José</p> <p class="dwt_publisher"></p> <p class="publishDate">2014-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">426</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.sfu.ca/content/dam/sfu/students/health/pdf/HealthyEating_Cheap%20and%20Easy.pdf"> <span id="translatedtitle"><span class="hlt">healthy</span> eating CHEAP AND EASY</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.osti.gov/epsearch/">E-print Network</a></p> <p class="result-summary">for <span class="hlt">healthy</span> meals. <span class="hlt">healthy</span> eating CHEAP AND EASY For more information on <span class="hlt">healthy</span> eating, call 1-800-667-DIET example eating <span class="hlt">healthy</span> foods more often offering meals and snacks at regular times, and giving your kids a variety of foods at meals and snacks. children NEED <span class="hlt">HEALTHY</span> FOOD <span class="hlt">healthy</span> eating doesn't mean forcing kids</p> <div class="credits"> <p class="dwt_author"></p> <p class="dwt_publisher"></p> <p class="publishDate"></p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">427</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.ncbi.nlm.nih.gov/pubmed/11258227"> <span id="translatedtitle">Separated <span class="hlt">twins</span> and the genetics of personality differences: a critique.</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p class="result-summary">This article discusses studies of separated <span class="hlt">twins</span>, with special emphasis on the Minnesota Study of <span class="hlt">Twins</span> Reared Apart (MISTRA), to determine whether they support the existence of an important genetic component in behavioral and personality differences. The methods and conclusions of the MISTRA team are discussed in the context of earlier studies of separated identical <span class="hlt">twins</span>. I argue that volunteer-based studies are biased toward greater <span class="hlt">twin</span> similarity. In addition, the MISTRA research team did not publish or share raw data and case history information. Reared-together and reared-apart monozygotic <span class="hlt">twins</span> share important environmental similarities not controlled for by comparing personality correlations. I propose an alternative control group consisting of biologically unrelated pairs of strangers matched on all environmental factors common to pairs of separated monozygotic <span class="hlt">twins</span>. I conclude that the evidence from studies of <span class="hlt">twins</span> reared apart does not support the role of genetic factors in personality and behavioral differences. PMID:11258227</p> <div class="credits"> <p class="dwt_author">Joseph, J</p> <p class="dwt_publisher"></p> <p class="publishDate">2001-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">428</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.ncbi.nlm.nih.gov/pubmed/25116815"> <span id="translatedtitle">Neuropathic pain in two-generation <span class="hlt">twins</span> carrying the sodium channel Nav1.7 functional variant R1150W.</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p class="result-summary">We present clinical, neuropathological, and molecular genetic findings of a family with a new pain phenotype of the sodium channel gene SCN9A polymorphism R1150W. A 46-year-old woman presented with a 5-year history of episodic temperature- and exercise-dependent burning pain of the feet and lower legs associated with numbness of the distal upper and lower limbs. Her monozygotic <span class="hlt">twin</span> <span class="hlt">sister</span> and their mother and her <span class="hlt">twin</span> presented similar symptoms. Clinical evaluation was normal except for a mild distal sensory deficit in fingers and feet. Electrophysiological testing was unremarkable, as were serum and cerebrospinal fluid laboratory findings. Skin biopsies of the distal lower limbs revealed an epidermal nerve fiber density at the lower limit of normal. Myelinated dermal nerve fibers showed elongated nodes of Ranvier, but normal distribution of nodal and paranodal proteins. Genetic testing for ion channel-associated pain disorders revealed an amino acid R1150W substitution of the Nav1.7 sodium channel. The combination of a Nav1.7 polymorphism with dysmyelinating features in small-caliber peripheral nerves has not been described before and may suggest an explanation for the clinical syndrome in our patients. Treatment with the sodium channel blocker lamotrigine provided some relief, consistent with a role of sodium channel dysfunction in the pain syndrome of this family. PMID:25116815</p> <div class="credits"> <p class="dwt_author">Harrer, Judith U; Uçeyler, Nurcan; Doppler, Kathrin; Fischer, Tanya Z; Dib-Hajj, Sulayman D; Waxman, Stephen G; Sommer, Claudia</p> <p class="dwt_publisher"></p> <p class="publishDate">2014-10-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">429</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.ncbi.nlm.nih.gov/pubmed/23398750"> <span id="translatedtitle">Maternal age at first birth and offspring criminality: using the children of <span class="hlt">twins</span> design to test causal hypotheses.</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p class="result-summary">Teenage childbirth is a risk factor for poor offspring outcomes, particularly offspring antisocial behavior. It is not clear, however, if maternal age at first birth (MAFB) is causally associated with offspring antisocial behavior or if this association is due to selection factors that influence both the likelihood that a young woman gives birth early and that her offspring engage in antisocial behavior. The current study addresses the limitations of previous research by using longitudinal data from Swedish national registries and children of siblings and children of <span class="hlt">twins</span> comparisons to identify the extent to which the association between MAFB and offspring criminal convictions is consistent with a causal influence and confounded by genetic or environmental factors that make cousins similar. We found offspring born to mothers who began childbearing earlier were more likely to be convicted of a crime than offspring born to mothers who delayed childbearing. The results from comparisons of differentially exposed cousins, especially born to discordant monozygotic <span class="hlt">twin</span> <span class="hlt">sisters</span>, provide support for a causal association between MAFB and offspring criminal convictions. The analyses also found little evidence for genetic confounding due to passive gene-environment correlation. Future studies are needed to replicate these findings and to identify environmental risk factors that mediate this causal association. PMID:23398750</p> <div class="credits"> <p class="dwt_author">Coyne, Claire A; Långström, Niklas; Rickert, Martin E; Lichtenstein, Paul; D'Onofrio, Brian M</p> <p class="dwt_publisher"></p> <p class="publishDate">2013-02-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">430</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3671761"> <span id="translatedtitle">Maternal age at first birth and offspring criminality: Using the children-of-<span class="hlt">twins</span> design to test causal hypotheses</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p class="result-summary">Teenage childbirth is a risk factor for poor offspring outcomes, particularly offspring antisocial behaviour. It is not clear if maternal age at first birth (MAFB) is causally associated with offspring antisocial behavior or if this association is due to selection factors that influence both the likelihood that a young woman gives birth early and that her offspring engage in antisocial behavior. The current study addresses the limitations of previous research by using longitudinal data from Swedish national registries and children-of-siblings and children-of-<span class="hlt">twins</span> comparisons to identify the extent to which the association between MAFB and offspring criminal convictions is consistent with a causal influence and confounded by genetic or environmental factors that make cousins similar. We found offspring born to mothers who began childbearing earlier were more likely to be convicted of a crime than offspring born to mothers who delayed childbearing. The results from comparisons of differentially exposed cousins, especially born to discordant MZ <span class="hlt">twin</span> <span class="hlt">sisters</span>, provide support for a causal association between MAFB and offspring criminal convictions. The analyses also found little evidence for genetic confounding due to passive gene-environment correlation. Future studies are needed to replicate these findings and to identify environmental risk factors that mediate this causal association. PMID:23398750</p> <div class="credits"> <p class="dwt_author">Coyne, Claire A; Langstrom, Niklas; Rickert, Martin E; Lichtenstein, Paul; D'Onofrio, Brian M</p> <p class="dwt_publisher"></p> <p class="publishDate">2013-01-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">431</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.usfca.edu/fac-staff/dever/StayHealthy.pdf"> <span id="translatedtitle">Staying <span class="hlt">Healthy</span> I. What is <span class="hlt">healthy</span>?</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.osti.gov/epsearch/">E-print Network</a></p> <p class="result-summary">fruits, vegetables, whole grains, and fat-free or low-fat milk and milk products in saturated fats, trans fats, cholesterol, salt (sodium), and added sugars. C. How of fat = 9 calories Obesity related health problems: B. Key to a <span class="hlt">healthy</span> diet: Ã?</p> <div class="credits"> <p class="dwt_author">Dever, Jennifer A.</p> <p class="dwt_publisher"></p> <p class="publishDate"></p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">432</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.ncbi.nlm.nih.gov/pubmed/18251684"> <span id="translatedtitle">Personality and birth order in monozygotic <span class="hlt">twins</span> adopted apart: a test of Sulloway's theory; Research Reviews: <span class="hlt">twin</span> births and cancer risk in mothers, male sexual dysfunction, <span class="hlt">twin</span> study of ultimatum game behavior; Human Interest: 'The Land of <span class="hlt">Twins</span>', <span class="hlt">twin</span>-like reunion-I, <span class="hlt">twin</span>-like reunion-II.</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p class="result-summary">A brief overview of Sulloway's (1996) theory of birth order and personality is presented. A reared apart <span class="hlt">twin</span> approach for testing his personality findings regarding openness to experience and conscientiousness in first borns and later borns is described. This is followed by summaries of three recent <span class="hlt">twin</span> studies. The topics include cancer risk in mother of <span class="hlt">twins</span>, sexual dysfunction in males and responder behavior during ultimatum games. This article concludes with a discussion of <span class="hlt">twinning</span> rates and rituals among the Yoruba of western Nigeria, and descriptions of two unusual reunions between siblings and <span class="hlt">twins</span>. PMID:18251684</p> <div class="credits"> <p class="dwt_author">Segal, Nancy L</p> <p class="dwt_publisher"></p> <p class="publishDate">2008-02-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">433</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://eric.ed.gov/?q=promoting+AND+healthy+AND+eating&pg=6&id=ED416966"> <span id="translatedtitle">Promoting <span class="hlt">Healthy</span> Dietary Behaviors.</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p class="result-summary">This chapter reviews the research on promoting <span class="hlt">healthy</span> dietary behaviors in all youth, not just those who exhibit problems such as obesity or eating disorders. The first section of this chapter presents a rationale for addressing <span class="hlt">healthy</span> dietary behavior with children and adolescents, on the basis of the impact of these behaviors on short- and…</p> <div class="credits"> <p class="dwt_author">Perry, Cheryl L.; Story, Mary; Lytle, Leslie A.</p> <p class="dwt_publisher"></p> <p class="publishDate"></p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">434</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://eric.ed.gov/?q=healthy+AND+life&id=EJ896774"> <span id="translatedtitle">"<span class="hlt">Healthy</span>" Human Development Indices</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p class="result-summary">In the Human Development Index (HDI), life expectancy is the only indicator used in modeling the dimension "a long and <span class="hlt">healthy</span> life". Whereas life expectancy is a direct measure of quantity of life, it is only an indirect measure of <span class="hlt">healthy</span> years lived. In this paper we attempt to remedy this omission by introducing into the HDI the morbidity…</p> <div class="credits"> <p class="dwt_author">Engineer, Merwan; Roy, Nilanjana; Fink, Sari</p> <p class="dwt_publisher"></p> <p class="publishDate">2010-01-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">435</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://eric.ed.gov/?q=consumer+AND+environment&pg=2&id=EJ1042704"> <span id="translatedtitle"><span class="hlt">Healthy</span> Homes Tools</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p class="result-summary">Extension is focusing on <span class="hlt">healthy</span> homes programming. Extension educators are not qualified to diagnose consumers' medical problems as they relate to housing. We cannot give medical advice. Instead, we can help educate consumers about home conditions that may affect their well-being. Extension educators need appropriate <span class="hlt">healthy</span> homes tools to…</p> <div class="credits"> <p class="dwt_author">Peek, Gina; Lyon, Melinda; Russ, Randall</p> <p class="dwt_publisher"></p> <p class="publishDate">2012-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">436</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.ncbi.nlm.nih.gov/pubmed/16008789"> <span id="translatedtitle">Mate choice and friendship in <span class="hlt">twins</span>: evidence for genetic similarity.</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p class="result-summary">This study examined the genetic and environmental contribution to people's preference for spouses and friends to be similar to themselves. In their responses to 130 personality, attitude, and demographic questions, 174 pairs of monozygotic (MZ) <span class="hlt">twins</span> resembled each other (r= .53) more than did 148 pairs of dizygotic (DZ) <span class="hlt">twins</span> (r= .32), 322 pairs of spouses (r= .32), and 563 pairs of best friends (r= .20). It was not previously recognized that spouses and friends are as similar as DZ <span class="hlt">twins</span>. MZ <span class="hlt">twins</span> also chose spouses and best friends more similar to their co-<span class="hlt">twins</span>' friends and spouses than did DZ <span class="hlt">twins</span> (mean rs = .22 vs. .14). The <span class="hlt">twins</span>' preference for spouses and friends similar to themselves was about 34% due to the <span class="hlt">twins</span>' genes, 12% due to the <span class="hlt">twins</span>' common environment, and 54% due to the <span class="hlt">twins</span>' unique (nonshared) environment. Similarity to partners was more pronounced on the more heritable items than the less heritable items. It is concluded that people are genetically inclined to choose as social partners those who resemble themselves at a genetic level. PMID:16008789</p> <div class="credits"> <p class="dwt_author">Rushton, J Philippe; Bons, Trudy Ann</p> <p class="dwt_publisher"></p> <p class="publishDate">2005-07-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">437</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1060943"> <span id="translatedtitle">A study of the fertility of mothers of <span class="hlt">twins</span>.</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p class="result-summary">Data on all births to Birmingham residents during a ten-year period were used to compare the reproductive history of mothers immediately before and after a <span class="hlt">twin</span> maternity with that of mothers of similar age and parity before and after a single birth. It was found that mothers of <span class="hlt">twins</span> were less likely than mothers of singletons to have a subsequent birth if both <span class="hlt">twins</span> survived, but if only one survived there was little difference between the two groups. If both <span class="hlt">twins</span> died, however, the likelihood of a later birth was increased. The interval before the next birth was longer than expected when both <span class="hlt">twins</span> survived and much shorter when both died. The sex of the <span class="hlt">twins</span> appeared to have little influence on subsequent reproduction, in spite of the fact that for singleton-containing fraternities a further pregnancy was more likely if the first two children were of the same sex than if they were of opposite sexes. The mean interval preceding a <span class="hlt">twin</span> maternity was almost the same as that preceding a single birth when both <span class="hlt">twins</span> survived, but it was shorter when one <span class="hlt">twin</span> died (being similar to that preceding the birth of a singleton who died) and it was much shorter when both <span class="hlt">twins</span> died. PMID:711977</p> <div class="credits"> <p class="dwt_author">Record, R G; Armstrong, E; Lancashire, R J</p> <p class="dwt_publisher"></p> <p class="publishDate">1978-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">438</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.ncbi.nlm.nih.gov/pubmed/711977"> <span id="translatedtitle">A study of the fertility of mothers of <span class="hlt">twins</span>.</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p class="result-summary">Data on all births to Birmingham residents during a ten-year period were used to compare the reproductive history of mothers immediately before and after a <span class="hlt">twin</span> maternity with that of mothers of similar age and parity before and after a single birth. It was found that mothers of <span class="hlt">twins</span> were less likely than mothers of singletons to have a subsequent birth if both <span class="hlt">twins</span> survived, but if only one survived there was little difference between the two groups. If both <span class="hlt">twins</span> died, however, the likelihood of a later birth was increased. The interval before the next birth was longer than expected when both <span class="hlt">twins</span> survived and much shorter when both died. The sex of the <span class="hlt">twins</span> appeared to have little influence on subsequent reproduction, in spite of the fact that for singleton-containing fraternities a further pregnancy was more likely if the first two children were of the same sex than if they were of opposite sexes. The mean interval preceding a <span class="hlt">twin</span> maternity was almost the same as that preceding a single birth when both <span class="hlt">twins</span> survived, but it was shorter when one <span class="hlt">twin</span> died (being similar to that preceding the birth of a singleton who died) and it was much shorter when both <span class="hlt">twins</span> died. PMID:711977</p> <div class="credits"> <p class="dwt_author">Record, R G; Armstrong, E; Lancashire, R J</p> <p class="dwt_publisher"></p> <p class="publishDate">1978-09-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">439</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://affordability.ku.edu/sites/affordability.ku.edu/files/docs/Heartland%20Health%20Lowell%20Kruse%202014%20application.pdf"> <span id="translatedtitle">LOWELL C. KRUSE <span class="hlt">HEALTHY</span> CHOICES. <span class="hlt">HEALTHY</span> LIVES. SCHOLARSHIP</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.osti.gov/epsearch/">E-print Network</a></p> <p class="result-summary">LOWELL C. KRUSE <span class="hlt">HEALTHY</span> CHOICES. <span class="hlt">HEALTHY</span> LIVES. SCHOLARSHIP Honoring the Legacy of Lowell C. Kruse CHOICES. <span class="hlt">HEALTHY</span> LIVES. SCHOLARSHIP Submission Deadline: June 16 PURPOSE The Lowell C. Kruse <span class="hlt">Healthy</span> Choices. <span class="hlt">Healthy</span> Lives. Scholarship was established in 2009 to provide financial assistance annually</p> <div class="credits"> <p class="dwt_author"></p> <p class="dwt_publisher"></p> <p class="publishDate"></p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">440</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2276995"> <span id="translatedtitle">Regulation of skeletal muscle PPAR? mRNA expression in <span class="hlt">twins</span></span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p class="result-summary">Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors regulating the expression of genes involved in lipid and glucose metabolism in a complex and to some extent unknown manner. Our aim was to study the impact of different factors on PPAR? mRNA expression in human skeletal muscle on one side, and the impact of PPAR? mRNA expression on these factors, including glucose and lipid metabolism, aerobic capacity, fibre type composition and lipid profile, on the other side. PPAR? mRNA levels were quantified by real-time PCR in muscle biopsies from 176 young and elderly monozygotic and dizygotic <span class="hlt">twins</span>. Young <span class="hlt">twins</span> had significantly increased PPAR? mRNA levels compared with elderly <span class="hlt">twins</span>. A 2 h hyperinsulinaemic euglycaemic clamp had no significant effect on PPAR? mRNA levels. Biometric models were calculated for basal PPAR? mRNA expression to estimate the degree of genetic versus environmental influence. In both young and elderly <span class="hlt">twins</span> there was a substantial genetic component influencing basal PPAR? mRNA levels. In a regression model, the muscle PPAR? mRNA expression was correlated to birth weight, central adiposity and age. The level of PPAR? mRNA was also positively correlated with markers for oxidative muscle fibres. However, in this apparently <span class="hlt">healthy</span> study population, we found no correlations between PPAR? mRNA expression and aerobic capacity, lipid profile or glucose and lipid metabolism. In conclusion, we provide evidence that mRNA expression of PPAR? in human skeletal muscle is under genetic control but also influenced by factors such as age, birth weight and central adiposity. PMID:17855759</p> <div class="credits"> <p class="dwt_author">Nilsson, Emma; Poulsen, Pernille; Sjogren, Marketa; Ling, Charlotte; Ridderstrale, Martin; Groop, Leif; Vaag, Allan</p> <p class="dwt_publisher"></p> <p class="publishDate">2007-01-01</p> </div> </div> </div> </div> <div id="filter_results_form" class="filter_results_form floatContainer" style="visibility: visible;"> <div style="width:100%" id="PaginatedNavigation" class="paginatedNavigationElement"> <a id="FirstPageLink" onclick='return showDiv("page_1");' href="#" title="First Page"> <img id="FirstPageLinkImage" class="Icon" src="http://www.science.gov/scigov/images/icon.first.18x20.png" alt="First Page" /></a> <a id="PreviousPageLink" onclick='return showDiv("page_21");' href="#" title="Previous Page"> <img id="PreviousPageLinkImage" class="Icon" src="http://www.science.gov/scigov/images/icon.previous.18x20.png" alt="Previous Page" /></a> <span id="PageLinks" class="pageLinks"> <span> <a onClick='return 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href="#">8</a> <a onClick='return showDiv("page_9");' href="#">9</a> <a onClick='return showDiv("page_10");' href="#">10</a> <a onClick='return showDiv("page_11");' href="#">11</a> <a onClick='return showDiv("page_12");' href="#">12</a> <a onClick='return showDiv("page_13");' href="#">13</a> <a onClick='return showDiv("page_14");' href="#">14</a> <a onClick='return showDiv("page_15");' href="#">15</a> <a onClick='return showDiv("page_16");' href="#">16</a> <a onClick='return showDiv("page_17");' href="#">17</a> <a onClick='return showDiv("page_18");' href="#">18</a> <a onClick='return showDiv("page_19");' href="#">19</a> <a onClick='return showDiv("page_20");' href="#">20</a> <a onClick='return showDiv("page_21");' href="#">21</a> <a onClick='return showDiv("page_22");' href="#">22</a> <a style="font-weight: bold;">23</a> <a onClick='return showDiv("page_24");' href="#">24</a> <a onClick='return showDiv("page_25");' href="#">25</a> </span> </span> <a id="NextPageLink" onclick='return showDiv("page_24");' href="#" title="Next Page"> <img id="NextPageLinkImage" class="Icon" src="http://www.science.gov/scigov/images/icon.next.18x20.png" alt="Next Page" /></a> <a id="LastPageLink" onclick='return showDiv("page_25.0");' href="#" title="Last Page"> <img id="LastPageLinkImage" class="Icon" src="http://www.science.gov/scigov/images/icon.last.18x20.png" alt="Last Page" /></a> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">441</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.osti.gov/scitech/servlets/purl/15011615"> <span id="translatedtitle">Nucleation and Propagation of Deformation <span class="hlt">Twin</span> in Polysynthetically <span class="hlt">Twinned</span> TiAl</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p class="result-summary">Using molecular dynamics simulations, we have studied the deformation of polysynthetically <span class="hlt">twinned</span> (PST) TiAl at room temperature with a bicrystal model. The simulation cell was pre-strained and thermodynamically relaxed to a criterion that all stress components of the simulation cell have gone to zeros; in this way no dislocations were pre-existed in {gamma}-{alpha}{sub 2} interfaces. A uniaxial compression was then applied along one 1/6<112] direction in the surface. The results show that under the compression, the interfacial dislocation pairs were prolifically generated due to the structural transformation of {alpha}{sub 2}-lamella. The gliding and agglomerating of these dislocations would finally cause the nucleation of deformation <span class="hlt">twins</span> from the interface. This is suggested to be a new possible <span class="hlt">twinning</span> mechanism in the dual phase TiAl alloy. The propagation of this deformation <span class="hlt">twin</span>, or specifically, its interaction with {gamma}-{gamma} and {gamma}-{alpha}{sub 2} interfaces has been discussed. It shows that the {alpha}{sub 2}-lamella is intent to block the propagation of the deformation <span class="hlt">twin</span>.</p> <div class="credits"> <p class="dwt_author">Zhou, L G; Hsiung, L M; Huang, H</p> <p class="dwt_publisher"></p> <p class="publishDate">2004-11-16</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">442</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.ncbi.nlm.nih.gov/pubmed/24224154"> <span id="translatedtitle">Congenital chloride diarrhea in dizygotic <span class="hlt">twins</span>.</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p class="result-summary">Congenital chloride diarrhea (CLD) is a rare inherited autosomal recessive disorder. Mutations of the solute carrier family 26 member 3 gene cause profuse, chloride ion rich diarrhea, which results in hypochloremia, hyponatremia and metabolic alkalosis with dehydration. If a fetal ultrasound shows bowel dilatation suggestive of bowel obstruction, or if a neonate shows persistent diarrhea and metabolic alkalosis, CLD should be considered in the differential diagnosis. The severity of CLD varies, but early detection and early therapy can prevent complications including growth failure. We report a case of dizygotic <span class="hlt">twins</span> affected by CLD who had been born to non-consanguineous parents. Both of them showed growth failure, but one of the <span class="hlt">twins</span> experienced worse clinical course. He showed developmental delay, along with dehydration and severe electrolyte imbalance. He was diagnosed with CLD first at 6-month age, and then the other one was also diagnosed with CLD. PMID:24224154</p> <div class="credits"> <p class="dwt_author">Seo, Kyung Ah; Lee, Na Mi; Kim, Gwang Jun; Yun, Sin Weon; Chae, Soo Ahn; Lim, In Seok; Choi, Eung Sang; Yoo, Byoung Hoon</p> <p class="dwt_publisher"></p> <p class="publishDate">2013-09-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">443</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.ncbi.nlm.nih.gov/pubmed/20508632"> <span id="translatedtitle">Case report: a black and white <span class="hlt">twin</span>.</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p class="result-summary">Albinism is an autosomal recessive disorder that is caused by a defective synthesis of melanin, resulting in a generalized reduction of pigmentation in the skin, hair and eyes, and leading to an increased risk of skin cancer and vision problems. We report a case of a 22-year-old primigravida of Negroid origin who delivered dichorial diamniotic <span class="hlt">twins</span>: two daughters were born with a totally different appearance. The first child had a light brown skin, black curly hair and brown eyes, whereas the second had a striking white skin, red-blond curly hair and blue eyes. Oculocutaneous albinism (OCA) and heteropaternal superfecundation were considered in the differential diagnosis. Genetic testing confirmed the diagnosis of OCA type 2 in the second child. The diagnosis of albinism has clinical implications and must be considered when a black and white <span class="hlt">twin</span> is born. PMID:20508632</p> <div class="credits"> <p class="dwt_author">Claas, M J; Timmermans, A; Bruinse, H W</p> <p class="dwt_publisher"></p> <p class="publishDate">2010-06-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">444</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.ncbi.nlm.nih.gov/pubmed/17219814"> <span id="translatedtitle">[Superfecundation in etiology of <span class="hlt">twin</span> pregnancy].</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p class="result-summary">Superfecundation is the fertilisation of two or more ova from the same cycle by sperm from separate acts of sexual intercourse. The term is also sometimes used to refer to the instances of two different males fathering fraternal <span class="hlt">twins</span>, though this is more accurately known as heteropaternal superfecundation. This therefore leads to the possibility of <span class="hlt">twins</span> also being half-siblings. This way of formation of multiply pregnancy aroused and it arouses still among doctors on whole world. This problem aroused large interest also among Polish doctors. For example, we found mention of superfecundation in first Polish medical journal, in Primitiae physico-medicae..., given in Leszno in years 1750-1753. Authors introduced relate opinion of superfecundation in aetiology of multiple pregnancies in historical aspect, as early as from Old Testament to present times as well as current state of medical knowledge of such a situation. PMID:17219814</p> <div class="credits"> <p class="dwt_author">Malinowski, Witold; Waszy?ski, Edmund</p> <p class="dwt_publisher"></p> <p class="publishDate">2006-10-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">445</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.ncbi.nlm.nih.gov/pubmed/21220281"> <span id="translatedtitle">Exoplanets: the quest for Earth <span class="hlt">twins</span>.</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p class="result-summary">Today, more than 400 extra-solar planets have been discovered. They provide strong constraints on the structure and formation mechanisms of planetary systems. Despite this huge amount of data, we still have little information concerning the constraints for extra-terrestrial life, i.e. the frequency of Earth <span class="hlt">twins</span> in the habitable zone and the distribution of their orbital eccentricities. On the other hand, these latter questions strongly excite general interest and trigger future searches for life in the Universe. The status of the extra-solar planets field--in particular with respect to very-low-mass planets--will be discussed and an outlook on the search for Earth <span class="hlt">twins</span> will be given in this paper. PMID:21220281</p> <div class="credits"> <p class="dwt_author">Mayor, Michel; Udry, Stephane; Pepe, Francesco; Lovis, Christophe</p> <p class="dwt_publisher"></p> <p class="publishDate">2011-02-13</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">446</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://adsabs.harvard.edu/abs/1985STIN...8617666W"> <span id="translatedtitle">Hot Gas Laboratory <span class="hlt">twin</span> nozzle calibration</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p class="result-summary">The quality of a <span class="hlt">twin</span> nozzle flow is investigated. The assembly was manufactured to produce high temperature jet related data relevant to VSTOL aircraft when adapted to a wind tunnel hot gas facility. The <span class="hlt">twin</span> nozzles are of an Ni-resistant flake cast iron construction whereas the standard 120 mm diameter single nozzle is a stainless steel, water-cooled fabrication. A calibration rake was used to acquire pressure and temperature data over an array of data points. The tests show that the construction method is satisfactory. The total pressure quality in the exit plane is good. A negative temperature gradient is found along the y axis. The nozzle reference pressure is a good indication of the average total pressure in the exit plane.</p> <div class="credits"> <p class="dwt_author">Winstanley, A. P.</p> <p class="dwt_publisher"></p> <p class="publishDate">1985-07-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">447</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://academic.research.microsoft.com/Publication/32593317"> <span id="translatedtitle">Morbidity and mortality of discordant <span class="hlt">twins</span> up to 34 weeks of gestational age</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://academic.research.microsoft.com/">Microsoft Academic Search </a></p> <p class="result-summary">The combination of weight discordance and prematurity implies a high perinatal morbidity and mortality for the affected <span class="hlt">twins</span>. Several pathomechanisms may be responsible for the weight difference in <span class="hlt">twins</span> including a different genetic growth potential in dizygotic <span class="hlt">twins</span>, placenta insufficiency in one <span class="hlt">twin</span>, and chronic feto-fetal transfusion (CFFT). Little is known about neonatal morbidity and mortality of discordant <span class="hlt">twins</span>. Therefore,</p> <div class="credits"> <p class="dwt_author">H. Schröder; J. Sonntag; S. Waltz; T. Schollmeyer; U. Schüppler; D. Weisner</p> <p class="dwt_publisher"></p> <p class="publishDate">1996-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">448</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.springerlink.com/index/e8g8771g40102604.pdf"> <span id="translatedtitle">Fanconi’s anemia in monozygotic <span class="hlt">twins</span></span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://academic.research.microsoft.com/">Microsoft Academic Search </a></p> <p class="result-summary">Fanconi’s anemia is one of the inherited causes of bone marrow failure. It is inherited in autosomal recessive fashion. It\\u000a presents as aplastic anemia usually at the age of 7–8 yr. Leukemias and solid tumours are complications in those who manage\\u000a to survive beyond two decades. Though it has been seen in siblings, reports in monozygotic <span class="hlt">twins</span> have been very</p> <div class="credits"> <p class="dwt_author">Fulton D’souza; M. K. Usha; S. D. Subba Rao</p> <p class="dwt_publisher"></p> <p class="publishDate">2007-01-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">449</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://academic.research.microsoft.com/Publication/36757333"> <span id="translatedtitle">A <span class="hlt">Twin</span> Study of Intracerebral Volumetric Relationships</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://academic.research.microsoft.com/">Microsoft Academic Search </a></p> <p class="result-summary">Using high resolution magnetic resonance imaging data, we examined the interrelationships between eight cerebral lobar volumetric\\u000a measures via both exploratory and confirmatory factor analyses in a large sample (N = 484) of pediatric <span class="hlt">twins</span> and singletons. These analyses suggest the presence of strong genetic correlations between cerebral\\u000a structures, particularly between regions of like tissue type or in spatial proximity. Structural modeling estimated</p> <div class="credits"> <p class="dwt_author">J. Eric Schmitt; Gregory L. Wallace; Rhoshel K. Lenroot; Sarah E. Ordaz; Dede Greenstein; Liv Clasen; Kenneth S. Kendler; Michael C. Neale; Jay N. Giedd</p> <p class="dwt_publisher"></p> <p class="publishDate">2010-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">450</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.ncbi.nlm.nih.gov/pubmed/25129257"> <span id="translatedtitle">A novel frameshift mutation in BLM gene associated with high <span class="hlt">sister</span> chromatid exchanges (SCE) in heterozygous family members.</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p class="result-summary">The Bloom syndrome (BS) is an autosomic recessive disorder comprising a wide range of abnormalities, including stunted growth, immunodeficiency, sun sensitivity and increased frequency of various types of cancer. Bloom syndrome cells display a high level of genetic instability, including a 10-fold increase in the <span class="hlt">sister</span> chromatid exchanges (SCE) level. Bloom syndrome arises through mutations in both alleles of the BLM gene, which was identified as a member of the RecQ helicase family. In this study, we screened a Tunisian family with three BS patients. Cytogenetic analysis showed several chromosomal aberrations, and an approximately 14-fold elevated SCE frequency in BS cells. A significant increase in SCE frequency was observed in some family members but not reaching the BS patients values, leading to suggest that this could be due to the heterozygous profile. Microsatellite genotyping using four fluorescent dye-labeled microsatellite markers revealed evidence of linkage to BLM locus and the <span class="hlt">healthy</span> members, sharing higher SCE frequency, showed heterozygous haplotypes as expected. Additionally, the direct BLM gene sequencing identified a novel homozygous frameshift mutation c.3617-3619delAA (p.K1207fsX9) in BS patients and a heterozygous BLM mutation in the family members with higher SCE frequency. Our findings suggest that this latter mutation likely leads to a reduced BLM activity explaining the homologous recombination repair defect and, therefore, the increase in SCE. Based on the present data, the screening of this mutation could contribute to the rapid diagnosis of BS. The genetic confirmation of the mutation in BLM gene provides crucial information for genetic counseling and prenatal diagnosis. PMID:25129257</p> <div class="credits"> <p class="dwt_author">Ben Salah, Ghada; Hadj Salem, Ikhlas; Masmoudi, Abderrahmen; Kallabi, Fakhri; Turki, Hamida; Fakhfakh, Faiza; Ayadi, Hamadi; Kamoun, Hassen</p> <p class="dwt_publisher"></p> <p class="publishDate">2014-11-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">451</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.ncbi.nlm.nih.gov/pubmed/25149956"> <span id="translatedtitle">Fraternal <span class="hlt">twins</span> with autism, severe cognitive deficit, and epilepsy: diagnostic role of chromosomal microarray analysis.</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p class="result-summary">A 7-year-old child presented with atypical absence epilepsy. He also had autism and severe cognitive deficit. As part of his diagnostic workup, a chromosomal microarray analysis was performed, which showed novel biallelic deletions in the neurexin 1 gene (NRXN1). His fraternal <span class="hlt">twin</span> <span class="hlt">sister</span>, who also had autism and cognitive impairment, was subsequently found to have the same biallelic deletions. Deletions included a 272-282kb loss at band 2p16.3 in one allele and a smaller 135-174-kb loss on the second allele. Neurexin 1 (NRXN1) is a cell adhesion protein, forming a synaptic complex with neuroligin. This signals a pathway that is critical for activity-dependent synaptic transmission. Mutations in this gene have been associated with autism and neurodevelopmental delay. Although there are many reports of heterozygous mutations with variable expressivity, only 3 cases with biallelic NRXN1 mutations have been previously reported, all of which have a more severe phenotype. We report 2 siblings with biallelic deletions, both of which affect the promoter region and exons 1-5 in the ?-NRXN1 isoform, which has a role in the Ca(2+)-dependent release of neurotransmitters in the central nervous system. Our cases expand the phenotype of biallelic ? NRXN 1 mutations and emphasize the important role of NRXN1 in autism and intellectual disability. Chromosomal microarray analysis should be the clinical standard in all specialties for first-tier genetic testing in autistic spectrum disorders. PMID:25149956</p> <div class="credits"> <p class="dwt_author">Imitola, Jaime; Walleigh, Diana; Anderson, Carol E; Jethva, Reena; Carvalho, Karen S; Legido, Agustin; Khurana, Divya S</p> <p class="dwt_publisher"></p> <p class="publishDate">2014-06-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">452</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3429432"> <span id="translatedtitle">The First Record of a Trans-Oceanic <span class="hlt">Sister</span>-Group Relationship between Obligate Vertebrate Troglobites</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p class="result-summary">We show using the most complete phylogeny of one of the most species-rich orders of vertebrates (Gobiiformes), and calibrations from the rich fossil record of teleost fishes, that the genus Typhleotris, endemic to subterranean karst habitats in southwestern Madagascar, is the <span class="hlt">sister</span> group to Milyeringa, endemic to similar subterranean systems in northwestern Australia. Both groups are eyeless, and our phylogenetic and biogeographic results show that these obligate cave fishes now found on opposite ends of the Indian Ocean (separated by nearly 7,000 km) are each others closest relatives and owe their origins to the break up of the southern supercontinent, Gondwana, at the end of the Cretaceous period. Trans-oceanic <span class="hlt">sister</span>-group relationships are otherwise unknown between blind, cave-adapted vertebrates and our results provide an extraordinary case of Gondwanan vicariance. PMID:22937155</p> <div class="credits"> <p class="dwt_author">Chakrabarty, Prosanta; Davis, Matthew P.; Sparks, John S.</p> <p class="dwt_publisher"></p> <p class="publishDate">2012-01-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">453</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.osti.gov/scitech/biblio/6052504"> <span id="translatedtitle">Frequency of <span class="hlt">sister</span> chromatid exchange in peripheral lymphocytes of male pesticide applicators</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p class="result-summary">In the present study 61 male pesticide applicators who worked in cotton fields and regularly sprayed pesticides such as DDT, BHC, endosulfan, malathion, methyl parathion, phosphamidon, dimethoate, monocrotophos, quinalphos fenvelrate, and cypermethrin were analyzed for <span class="hlt">sister</span> chromatid exchanges, mitotic index, and cell cycle kinetics in peripheral lymphocytes. Subjects who handled pesticides were non-smokers and teetotalers and the data were compared with the matched control group. Statistical analysis revealed that the frequency of <span class="hlt">sister</span> chromatid exchanges was significantly higher among the pesticide applicators at all the durations of exposure when compared to controls. Subjects exposed to pesticides also showed cell cycle delay and decrease in mitotic index when compared to the control group.</p> <div class="credits"> <p class="dwt_author">Rupa, D.S. (Univ. of California, Riverside (United States)); Reddy, P.P. (Inst. of Genetics, Hyderabad (India)); Sreemannarayana, K. (Sree Venkateswara Eye Clinic, Ongole (India)); Reddi, O.S. (Inst. of Molecular Immunology and Biotechnology, Hyderabad (India))</p> <p class="dwt_publisher"></p> <p class="publishDate">1991-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">454</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://adsabs.harvard.edu/abs/2009AGUSMSM73A..06K"> <span id="translatedtitle">First Ion Temperature Images From <span class="hlt">TWINS</span> Data</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p class="result-summary">Ion heating has been correlated with several magnetospheric phenomena, including magnetic reconnection, instabilities, and convection of plasma through different regions of the magnetosphere. Thus, it important to be able to measure ion temperatures throughout the magnetosphere to better understand the physics of these phenomena. Effective ion temperatures based on the charge-exchange cross section-corrected energetic neutral atom (ENA) flux versus energy spectrum can be calculated from <span class="hlt">TWINS</span> data. Effective ion temperatures calculated from the Medium Energy Neutral Atom (MENA) imager on the IMAGE spacecraft using this technique were shown to have excellent (within ~30%) agreement with in-situ measurements from MPA instruments on LANL geosynchronous spacecraft and GEOTAIL. In order to achieve adequate statistics for reliable ion temperature calculations, we can use either data with significant ENA flux rates, such as during geomagnetic storms, or superpositions of multiple data sets. We present ion temperature images from the few small storms that have occurred so far in the <span class="hlt">TWINS</span> mission. We will present both 'skymap' images as well as 2-D maps created using an algorithm to project the data along each pixel's line-of-sight to the equatorial plane of the Geocentric Solar Magnetospheric (GSM) coordinate system. During intervals for which data is available from both <span class="hlt">TWINS</span> I and II, we will compare the locations of interesting features as seen by the two satellites.</p> <div class="credits"> <p class="dwt_author">Keesee, A. M.; Scime, E.</p> <p class="dwt_publisher"></p> <p class="publishDate">2009-05-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">455</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://adsabs.harvard.edu/abs/2007PCM....34..529F"> <span id="translatedtitle">Cross-<span class="hlt">twinning</span> in a natural spinel from Sri Lanka</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p class="result-summary">A modified cross-<span class="hlt">twinning</span> growth mechanism is put forward to explain the anomalous morphology of a spinel multiple-<span class="hlt">twin</span> from Sri Lanka, flattened crosswise the <span class="hlt">twin</span> planes. Cross-<span class="hlt">twinning</span> in spinel was found also in other specimens from Pegu (Myanmar), and the results were published in a previous paper. This particular type of <span class="hlt">twinning</span> is derived from the combination of cyclic <span class="hlt">twinning</span> with lamellar <span class="hlt">twinning</span>, so that these samples may be thought of as partial fivelings (cubic cyclic {111} <span class="hlt">twins</span> with five components sharing a common <110> pseudo-fivefold axis). In the present paper, the sample from Sri Lanka has been suitably cut with the aim of focusing the study on the cross-<span class="hlt">twinning</span> region. The transformation matrices that link the orientation states of each couple of <span class="hlt">twin</span> components have been determined by means of White Beam Synchrotron Radiation Topography. They showed that the specimen is made up of four <span class="hlt">twin</span> components (A, B, C and D), with three <span class="hlt">twin</span> planes: (bar{1}11)_A/B, (1bar{1}bar{1})_B/C and (bar{1}bar{1}bar{1})_AC/D. They also showed that the cross-<span class="hlt">twinned</span> individuals (B and D) actually are not <span class="hlt">twinned</span> to each other, and that a simple crystallographic relationship holds between them. X-ray diffraction topography by conventional source allowed to image the crossing-region and to determine that the cross-<span class="hlt">twinned</span> individuals are in contact through a semi-coherent boundary, with <span class="hlt">twinning</span> dislocations contributing to relieve the coherency strains. Electron probe microanalyses with wave dispersive spectroscopy showed that the chemical composition is almost homogeneous, at least within the spatial resolution limit of this technique. The similar growth features observed in the spinel sample from Sri Lanka and in those from Myanmar are interpreted as growth marks, indicators of a similar origin: in both cases they are found in impure dolomitic marbles. In particular, the specimen from Sri Lanka results from the interaction of thermal and metasomatic effects due to contact metamorphism. An unusual stepped morphology of the (1bar{1}0)_C face close to the (bar{1}bar{1}bar{1})_C/D <span class="hlt">twin</span> boundary, possibly due to corrosion and re-growth processes acted preferentially at a re-entrant corner by metasomatic fluids, is interpreted as indicator of a metasomatic event that succeeded to the crystal growth, the latter occurred by thermal effect.</p> <div class="credits"> <p class="dwt_author">Fregola, Rosa Anna; Scandale, Eugenio</p> <p class="dwt_publisher"></p> <p class="publishDate">2007-10-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">456</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.springerlink.com/index/33112186130828l8.pdf"> <span id="translatedtitle">The effects of boric acid on <span class="hlt">sister</span> chromatid exchanges and chromosome aberrations in cultured human lymphocytes</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://academic.research.microsoft.com/">Microsoft Academic Search </a></p> <p class="result-summary">The aim of this study was to determine the possible genotoxic effects of boric acid (BA) (E284), which is used as an antimicrobial\\u000a agent in food, by using <span class="hlt">sister</span> chromatid exchange (SCEs) and chromosome aberration (CAs) tests in human peripheral lymphocytes.\\u000a The human lymphocytes were treated with 400, 600, 800, and 1000 ?g\\/mL concentrations of BA dissolved in dimethyl sulfoxide</p> <div class="credits"> <p class="dwt_author">Mehmet Arslan; Mehmet Topaktas; Eyyüp Rencuzogullari</p> <p class="dwt_publisher"></p> <p class="publishDate">2008-01-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">457</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1001901"> <span id="translatedtitle"><span class="hlt">Sister</span> chromatid exchange frequencies in patients with scleroderma and their relatives.</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p class="result-summary"><span class="hlt">Sister</span> chromatid exchange (SCE) analysis is a sensitive measure of chromosome damage induced by many agents which damage DNA. These agents have been reported to be present in the serum of patients with scleroderma. Chromosome aberrations are thought to be more common in cells of these patients and their relatives than in cells of controls. We have observed that the SCE frequencies in blood lymphocytes of patients with scleroderma and their relatives do not differ from those of controls. Images PMID:3718015</p> <div class="credits"> <p class="dwt_author">Palmer, R G; Pereira, R S; Dore, C J; Denman, A M</p> <p class="dwt_publisher"></p> <p class="publishDate">1986-01-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">458</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://kuscholarworks.ku.edu/handle/1808/12948"> <span id="translatedtitle">A Seamless Garment of Eco-Justice: Green <span class="hlt">Sisters</span> in Kansas</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.osti.gov/epsearch/">E-print Network</a></p> <p class="result-summary">religious adjusting collectively and individually to the changes of Vatican II grew into a strong network of activists tackling social justice issues ranging from human trafficking, domestic violence, child abuse, and elder care to radical peace movements... that addresses far-reaching social justice issues, ranging from human trafficking to fracking. The intention is to educate <span class="hlt">sisters</span>, primarily, on the complicated, interconnected issues of social justice. However, even a cursory glance at the Resolutions...</p> <div class="credits"> <p class="dwt_author">Myslivy, Rachel Ann Boeckman</p> <p class="dwt_publisher"></p> <p class="publishDate">2013-12-31</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">459</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.osti.gov/scitech/biblio/6885703"> <span id="translatedtitle"><span class="hlt">Sister</span> chromatid exchange analysis to monitor genotoxic chemicals. (Latest citations from Pollution Abstracts). Published Search</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p class="result-summary">The bibliography contains citations concerning the use of the <span class="hlt">sister</span> chromatid exchange (SCE) analysis for toxicological studies. SCE analysis are very sensitive measures of genotoxic damage to chromosomes. SCE toxicological studies analyzing ionizing radiation, chromium compounds, styrene, paint thinner, mercury, cigarette smoke, coal dust, fuel oil, insecticides, ethylene oxide, diesel exhaust, and polychlorinated biphenyls are discussed. SCE studies using both human and animal tissue cultures are described. (Contains a minimum of 191 citations and includes a subject term index and title list.)</p> <div class="credits"> <p class="dwt_author">Not Available</p> <p class="dwt_publisher"></p> <p class="publishDate">1993-03-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">460</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://academic.research.microsoft.com/Publication/31330482"> <span id="translatedtitle">Familial colloid cyst of the third ventricle in non-<span class="hlt">twin</span> <span class="hlt">sisters</span>: Case report, review of the literature, controversies, and screening strategies</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://academic.research.microsoft.com/">Microsoft Academic Search </a></p> <p class="result-summary">Colloid cyst of the third ventricle is a known primary brain tumor. The familial occurrence of this cyst and associated conditions has been rarely discussed in the literature. To our knowledge only 10 affected families have been previously reported in the literature. We report the 11th family with this potentially life-threatening tumor and discuss the associated conditions and, existing controversies</p> <div class="credits"> <p class="dwt_author">Moslem Shakeri Bavil; Payman Vahedi</p> <p class="dwt_publisher"></p> <p class="publishDate">2007-01-01</p> </div> </div> </div> </div> <div id="filter_results_form" class="filter_results_form floatContainer" style="visibility: visible;"> <div style="width:100%" id="PaginatedNavigation" class="paginatedNavigationElement"> <a id="FirstPageLink" onclick='return showDiv("page_1");' href="#" title="First Page"> <img id="FirstPageLinkImage" class="Icon" src="http://www.science.gov/scigov/images/icon.first.18x20.png" alt="First Page" /></a> <a id="PreviousPageLink" onclick='return showDiv("page_22");' href="#" title="Previous Page"> <img id="PreviousPageLinkImage" class="Icon" src="http://www.science.gov/scigov/images/icon.previous.18x20.png" alt="Previous Page" /></a> <span id="PageLinks" class="pageLinks"> 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showDiv("page_25");' href="#" title="Next Page"> <img id="NextPageLinkImage" class="Icon" src="http://www.science.gov/scigov/images/icon.next.18x20.png" alt="Next Page" /></a> <a id="LastPageLink" onclick='return showDiv("page_25.0");' href="#" title="Last Page"> <img id="LastPageLinkImage" class="Icon" src="http://www.science.gov/scigov/images/icon.last.18x20.png" alt="Last Page" /></a> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">461</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.ncbi.nlm.nih.gov/pubmed/8990532"> <span id="translatedtitle">Differential maternal treatment of infant <span class="hlt">twins</span>: effects of infant behaviors.</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p class="result-summary">This project utilized <span class="hlt">twins</span> to study differential mother-sibling interactions. The use of <span class="hlt">twins</span> circumvented the traditional confounds of studying siblings of different ages or at two points in time. When the <span class="hlt">twins</span> were 7 and 9 months of age, mothers spent 2.5 min alone with each infant in an attempt to elicit child vocalizations. The mother and infant behaviors were coded both microanalytically and globally. The infant attention behaviors were influenced primarily by unique environment, whereas the temperament behaviors were influenced by both unique environmental and genetic effects. Mothers tended to treat both children similarly, regardless of zygosity, suggesting that maternal characteristics drove the mother-infant interactions. Thus, even though identical <span class="hlt">twins</span> were more similar on some measures than fraternal <span class="hlt">twins</span>, mothers tended to treat both types of <span class="hlt">twins</span> comparably regardless of infant characteristics or behaviors. PMID:8990532</p> <div class="credits"> <p class="dwt_author">DiLalla, L F; Bishop, E G</p> <p class="dwt_publisher"></p> <p class="publishDate">1996-11-01</p> </div> </div> </div> </div> <div class="floatContainer result " lang="en"> <div class="resultNumber element">462</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.ncbi.nlm.nih.gov/pubmed/23811664"> <span id="translatedtitle">Heritability of thirty cephalometric parameters on monozygotic and dizygotic <span class="hlt">twins</span>: <span class="hlt">twin</span> study method.</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p class="result-summary">Genetic mechanisms are already predominant during embryonic craniofacial morphogenesis, but environment is also thought to influence dentofacial morphology postnatally, particularly during facial growth. A better understanding of the relative effects of genes and environment on dentofacial and occlusal parameters should improve our knowledge on the etiology of orthodontic disorders and therefore also on the possibilities and limitations of the orthodontic treatment and treatment planning. The aim of the present study is to explore the genetic and environmental influence on craniofacial dimensions in a group of 19 pairs of <span class="hlt">twins</span> using the <span class="hlt">twin</span> study method. The <span class="hlt">twin</span> study carried out here clearly indicates that craniofacial matrix is under substantial genetic control and the redirection of a basic growth pattern may be modified only within biological limits which are harmonious for the patient. PMID:23811664</p> <div class="credits"> <p class="dwt_author">Sreedevi, Gojja; Srinivas, Baratam; Reddy, T Praveen Kumar; Prasad, C M S Krishna; Kumar, B Sunil; Satish, R</p> <p class="dwt_publisher"></p> <p class="publishDate">2013-01-01</p> </div> </div> </div> </div> <div class="floatContainer result odd" lang="en"> <div class="resultNumber element">463</div> <div class="resultBody element"> <p class="result-title"><a target="resultTitleLink" href="http://science.gov/scigov/link.html?type=RESULT&redirectUrl=http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3135288"> <span id="translatedtitle">Roles of Vertebrate Smc5 in <span class="hlt">Sister</span> Chromatid Cohesion and Homologous Recombinational Repair ?</span></a>  </p> <div class="result-meta"> <p class="source"><a target="_blank" id="logoLink" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p class="result-summary">The structural maintenance of chromosomes (Smc) family members Smc5 and Smc6 are both essential in budding and fission yeasts. Yeast smc5/6 mutants are hypersensitive to DNA damage, and Smc5/6 is recruited to HO-induced double-strand breaks (DSBs), facilitating intersister chromatid recombinational repair. To determine the role of the vertebrate Smc5/6 complex during the normal cell cycle, we generated an Smc5-deficient chicken DT40 cell line using gene targeting. Surprisingly, Smc5? cells were viable, although they proliferated more slowly than controls and showed mitotic abnormalities. Smc5-deficient cells were sensitive to methyl methanesulfonate and ionizing radiation (IR) and showed increased chromosome aberration levels upon irradiation. Formation and resolution of Rad51 and gamma-H2AX