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1

Diet transiently improves migraine in two twin sisters: possible role of ketogenesis?  

PubMed Central

Summary The ketogenic diet is a high-fat, low-carbohydrate diet long used to treat refractory epilepsy; ketogenesis (ketone body formation) is a physiological phenomenon also observed in patients following low-carbohydrate, low-calorie diets prescribed for rapid weight loss. We report the case of a pair of twin sisters, whose high-frequency migraine improved during a ketogenic diet they followed in order to lose weight. The observed time-lock between ketogenesis and migraine improvement provides some insight into how ketones act to improve migraine. PMID:24598400

Di Lorenzo, Cherubino; Currŕ, Antonio; Sirianni, Giulio; Coppola, Gianluca; Bracaglia, Martina; Cardillo, Alessandra; De Nardis, Lorenzo; Pierelli, Francesco

2013-01-01

2

Analysis of bromodeoxyuridine-induced single and twin sister chromatid exchanges in tetraploid Chinese hamster ovary cells  

Microsoft Academic Search

Culture of cells in high exogenous levels (>10-4 M) of bromodeoxyuridine (BrdUrd) or thymidine will increase the baseline sister chromatid exchange (SCE) frequency. The effect is thought to be related to the balance of the DNA precursors thymidine and deoxycytidine. Exogenous addition of deoxycytidine will reverse this effect. Single and twin SCEs were analysed in Colcemid-induced tetraploid Chinese hamster ovary

Jeffrey L. Schwartz

1986-01-01

3

The Healthy Twin Study, Korea updates: resources for omics and genome epidemiology studies.  

PubMed

The Healthy Twin Study, Korea (HT) is an ongoing multi-center cohort study that was initiated in 2005, based on a nation-wide twin and family database. Since its inception, the HT has recruited 815 pairs of adult twins and a total of 3,690 individual twins and their families as of July 2012. Here we summarize updates since the previous report in 2006. Besides the increase in size, the HT has been enriched in several aspects: a biobank was constructed for ongoing and future omics studies; and genome-wide single nucleotide polymorphism markers (Affymetrix GeneChip version 6.0, 1 M probes) have been analyzed for 2,200 individuals, which enabled gene identification studies for measured phenotypes. In addition, longitudinal study protocols were established through the HT and a second wave survey was finished in 2010 with >70% follow-up rate. The parallel genome research projects were recently launched, which would expedite multi-omics studies maximizing the twin potentials such as metagenomics and epigenetics studies, and endow us with resources for recruiting more participants. We submit this report to share updates and research opportunities from the HT. PMID:23218411

Gombojav, Bayasgalan; Song, Yun-Mi; Lee, Kayoung; Yang, Sarah; Kho, Minjung; Hwang, Yong-Chul; Ko, Gwangpyo; Sung, Joohon

2013-02-01

4

First Language Attrition in the Speech of Dutch-English Bilinguals: The Case of Monozygotic Twin Sisters  

ERIC Educational Resources Information Center

Recent years have seen a proliferation of research on attrition in L1 speech (de Leeuw, Mennen & Scobbie, in press; de Leeuw, Schmid & Mennen, 2010; Dmitrieva, Jongman & Sereno, 2010; Mennen, 2004). Adding to this line of inquiry, the present study investigates the speech of a 62-year-old bilingual monozygotic twin who emigrated to an L2-speaking…

Mayr, Robert; Price, Sacha; Mennen, Ineke

2012-01-01

5

Twins  

NSDL National Science Digital Library

This collection of Web sites about twins and twin biology starts with a short feature from The Straight Dope (1), which explains the phenomenon of superfecundation. Next is a more extensive piece from Scientific American (2), offering an interesting look at the role genetics may play in the chance of having fraternal twins. The following Web site contains a brief MSNBC story on the recent findings that fraternal, or nonidentical, twins can share the same placenta (3). The Wisconsin Twin Project at the University of Wisconsin-Madison is a long-scale psychological study focused on "the genetic and environmental influences on normal development of twins in the family context." Visitors to the project's Web site (4) will find detailed information about the ongoing research as well as FAQs for general background information. On the topic of twin studies, the next Web site contains a transcript from a recent Health Report story from the Australian Broadcasting Company's Radio National. The transcript is an interview with a researcher working with the Swedish Twin Registry (the largest twin register in the world), an important resource for studying the "relative importance of genetic and environmental influences for behavioral characteristics and diseases (5). The journal Nature offers an interesting article on how the environment in the womb can have profound effects on a child's future health without altering its DNA sequence (6). The following Web site, created by Varun Tankala, offers an excellent introduction to the phenomenon of conjoined twins (7). And with the final Web site, you need not spend another restless night wondering which Star Wars character is your cosmic twin. Not as frivolous as it might seem, this Web site, created by Jeff Potter, contains a well-accepted personality test developed by a University of California-Berkeley psychologist. Users can take the test, find their Star Wars twin, and help advance the field of psychology while you're at it (8).

6

Sister Study  

Cancer.gov

The Sister Study, conducted by the National Institute of Environmental Health Sciences (NIEHS), is prospectively examining environmental and familial risk factors for breast cancer and other outcomes in a cohort of 50,884 sisters of women who have had breast cancer. These sisters have about twice the risk of developing breast cancer due to their family history and are expected to be highly motivated to participate in a long-term study.

7

YEAST MEIOSIS Sister kinetochores are mechanically  

E-print Network

YEAST MEIOSIS Sister kinetochores are mechanically fused during meiosis I in yeast Krishna K Production of healthy gametes requires a reductional meiosis I division in which replicated sister chromatids comigrate, rather than separate as in mitosis or meiosis II. Fusion of sister kinetochores during meiosis I

Asbury, Chip

8

Organ donation: a twin-based perspective.  

PubMed

Monozygotic cotwins are ideal organ donors for one another due to their genetic identity. The present report treats this topic differently, from the perspective of a monozygotic twin who donated her deceased twin sister's organs following her sister's untimely death. This discussion is followed by reviews of recent research concerning increased twinning rates in the United States, availability of informative kinship pedigrees, and twin discordance for physical activities. Noteworthy news items include ethical issues surrounding conjoined twin separation, a genomic discovery for diseased twins, China's One-Child Policy, a striking New Yorker Magazine cartoon, and twin delivery complications. PMID:22856360

Segal, Nancy L

2012-04-01

9

When You Are a Twin or Triplet  

MedlinePLUS

... identical twins usually look almost exactly alike and share the same genes . If you have friends who are twins ... twins often don't look alike and only share approximately half of the same genes — just like non-twin brothers and sisters ...

10

CEO Sister  

NSDL National Science Digital Library

Touted as the "nation's Number One destination for Minority Businesswomen," CEO Sister is designed to serve as an online community for businesswomen of color. Highlighted on the site are headlines from both the Washington Post and US News. A menu of resources is located in a blue box on the upper left corner of the site and contains information on higher education, ecommerce, and networking. Interested users may register to receive a lifetime email account with the site as well as access to chats and bulletin boards.

11

Alzheimer's disease in one monozygotic twin  

PubMed Central

A woman of 64 died after an illness lasting 15 years and characterized by a progressive amnesic syndrome followed by global dementia. The brain showed changes typical of Alzheimer's disease. Her monozygotic twin sister was clinically not affected and died two years later of carcinoma. This is the second report of monozygotic twin sisters apparently discordant for presenile dementia of Alzheimer type. PMID:5084139

Hunter, Richard; Dayan, A. D.; Wilson, John

1972-01-01

12

Case of early childhood-onset narcolepsy with cataplexy: comparison with a monozygotic co-twin.  

PubMed

We describe here a rare case of early childhood-onset (5 years of age) narcolepsy. This case was interesting because of the ability to compare the patient's symptoms to the condition of her healthy monozygotic co-twin sister. The only environmental difference between the co-twins was head injury, which may be associated with the presence of narcolepsy. The co-twin was extroverted, sociable, reliable, and dexterous. In contrast, the patient could be described as introverted, gentle, honest and persevering, but was weak at conversation, assessment of a situation, memory, planning, activity (she was inactive), a sense of time, understanding of an analog clock, operating efficiency, and physical education (due to obesity). The sisters showed the same degree of appetite and dexterity with their fingers. Narcolepsy is often under-recognized or underdiagnosed, especially when the onset occurs in childhood. When we observe preschoolers with excessive daytime sleepiness, we should consider the possibility of narcolepsy with cataplexy. PMID:25336002

Ito, Hiromichi; Mori, Kenji; Mori, Tatsuo; Goji, Aya; Kagami, Shoji

2014-10-01

13

Morphometric analysis of lateral ventricles in schizophrenia and healthy controls regarding  

E-print Network

(MZ) twin pairs discordant for schizophrenia (DS), healthy MZ twin pairs, healthy dizygotic twin pairs, heritability was examined by ventricle similarity between pairs of co-twins. Results show that co-twin analysis. Co-twin shape similarity of healthy MZ twins did not differ from DS MZ twins. Second, the disease

Gerig, Guido

14

A healthy delivery of twins by assisted reproduction followed by preimplantation genetic screening in a woman with X-linked dominant incontinentia pigmenti  

PubMed Central

The purpose of this study is to report a successful twin pregnancy and delivery in a female patient with X-linked dominant incontinentia pigmenti (IP) who underwent assisted reproductive technology followed by preimplantation genetic screening (PGS). A 29-year-old female with IP had a previous history of recurrent spontaneous abortion. A molecular analysis revealed the patient had a de novo mutation, 1308_1309insCCCCTTG(p.Ala438ProfsTer26), in the inhibitor of the kappa B kinase gamma gene located in the Xq28 region. IVF/ICSI and PGS was performed, in which male embryos were sexed using array-based comparative genomic hybridization (aCGH). After IVF/ICSI and PGS using aCGH on seven embryos, two euploid male blastocysts were transferred with a 50% probability of a viable male pregnancy. The dizygotic twin pregnancy was confirmed and the amniocentesis results of each twin were normal with regard to the mutation found in the mother. The patient delivered healthy twin babies during the 37th week of gestation. This case shows the beneficial role of PGS in achieving a successful pregnancy through euploid male embryo gender selection in a woman with X-linked dominant IP with a history of multiple male miscarriages. PMID:25599040

Kim, Myung Joo; Lyu, Sang Woo; Seok, Hyun Ha; Park, Ji Eun

2014-01-01

15

Middle Sister and Hayden Glacier  

USGS Multimedia Gallery

The North face of Middle Sister and Hayden Glacier, in Three Sisters Wilderness, Deschutes National Forest, Oregon. This Picture was taken while climbing Middle Sister. Middle Sister is also known as "Hope" and is an extinct stratovolcano....

2009-12-08

16

Comparison of the Gut Microbiotas of Healthy Adult Twins Living in South Korea and the United States ? †  

PubMed Central

We compared the composition of the fecal microbiotas of Korean and U.S. adult twins. Our data indicated that the gut microbiota shows some signature of biogeography, potentially mediated by differences in diet and/or other environmental factors; however, these regional differences may be masked by other phenotypic variations, such as obesity. PMID:21873488

Lee, Sunghee; Sung, Joohon; Lee, JungEun; Ko, GwangPyo

2011-01-01

17

“Do You Want Somebody Treating Your Sister Like That?”: Qualitative Exploration of How African American Families Discuss and Promote Healthy Teen Dating Relationships  

PubMed Central

The article discusses a study conducted between December 2007 and March 2008 that involved 19 gender-stratified focus groups with African American parents and adolescents from Allegheny County, Pennsylvania, to explore the process and content of parent–adolescent communication about sex. Discussions about intimate partner violence (IPV) and healthy relationships emerge inductively as critical topics in these conversations. The authors use a grounded theory approach to content analysis to identify and organize themes related to discussions on these topics. A total of 125 participants from 52 families are recruited for the study. Family history of child sexual abuse often motivates discussions. Mothers are described as the primary parent discussing sexual issues with children. Fathers primarily role model ideal male partnership behavior for sons and daughters. Parents seek to prevent daughters from experiencing sexual abuse or emotional manipulation by partners and focus on instilling a sense of responsibility to and respect for romantic partners in sons. Parents prioritize and express the need for tools to influence their adolescent’s socialization as romantic partners. Mothers and fathers approach this process differently. Family-focused interventions to prevent unhealthy relationships can build on parent’s efforts. PMID:20889536

Akers, Aletha Y.; Yonas, Michael; Burke, Jessica; Chang, Judy C.

2011-01-01

18

Sibling Conversations about Dating and Sexuality: Sisters as Confidants, Sources of Support, and Mentors.  

PubMed

Using an observational methodology to examine sibling communication, sisters (N = 28 dyads) were videotaped discussing their ideas about dating and sexuality. Social provision theory was used as a framework for the examination of roles enacted by sisters during these conversations. Inductive thematic analytic procedures were conducted and three roles were identified: sisters as confidants, sources of support, and mentors. Older and younger sisters both served as confidants and sources of support for one another, whereas, older sisters were more likely to be mentors for their younger sisters than vice versa. Findings indicate the potential importance of sisters in the formation of adolescent girls' ideas about romantic relationships and sexuality, sibling communication as a socialization mechanism of sisters' similarities in romantic experiences and sexual behaviors/attitudes, and the inclusion of older sisters in prevention intervention programs focused on reducing adolescent sexual risk behaviors and promoting healthy romantic relationships and sexuality development. PMID:24659843

Killoren, Sarah E; Roach, Andrea L

2014-04-01

19

Three Sisters, Oregon  

NSDL National Science Digital Library

Earlier this month, the US Geological Survey (USGS) released a report stating that USGS scientists have detected a slight uplift of the ground surface over a broad area centered 5 kilometers west of South Sister volcano in the Three Sisters region of the central Oregon Cascade Range. This uplift was detected using a relatively new technique, Satellite Radar Interferometry (InSAR). InSAR uses satellite data to make radar images of the Earth's surface and then compares images from the same location acquired at different times to detect minor (a few centimeters) changes in the ground elevation. This page comes from the USGS Cascades Volcano Observatory Website, and it contains links to the May 8 press release, current hazards report (spring 2001), geologic descriptions of the Three Sisters volcanoes, color interferograms, site photographs, earthquake maps, an overview of InSAR, daily seismicity measurements, and much more. The USGS's Cascade Volcano Observatory has been featured previously in our reports (see the September 23, 1994 Scout Report for Science & Engineering), but the Three Sisters research is particularly timely.

2001-01-01

20

Tough Little German Sister  

Microsoft Academic Search

Caroline Herschel, 1750-1848, was born in Germany and was the sister of Sir William Herschel, discoverer of Uranus and Astronomer Royal to England's King George III. Never married, she was her brother's assistant all her life. She is credited with the discovery of eight comets, the winner of several awards, and respected in her own right as an astronomer.

Barbara S. Ryden

2000-01-01

21

Isolated oligodontia in monozygotic twins  

PubMed Central

This case report defines a case of isolated oligodontia of 9 and 10 permanent teeth in 9-year-old monozygotic twin sisters and gives information about the possible genetic and environmental etiology, related dental anomalies and treatment options. The twins have a negative family history of hypodontia and oligodontia in their parents, as well as their paternal and maternal grandmothers and first cousins. No other dental anomalies could be detected in either of the twins. With the occurrence of similarly located tooth agenesis, except for one tooth, in monozygotic twins, one may consider the influence of genetic and/or environmental factors in their etiology. Hereditary relationships associated with oligodontia could help the clinicians to predict the possibility of its occurrence in other family members and in the next generations. However, clinicians should consider oligodontia when it is not hereditary. PMID:24966717

Halicioglu, Koray; Sahin, Hakan; Corekci, Bayram; Irgin, Celal; Toptas, Orcun

2013-01-01

22

Sister Chromatid Cohesion  

PubMed Central

During S phase, not only does DNA have to be replicated, but also newly synthesized DNA molecules have to be connected with each other. This sister chromatid cohesion is essential for the biorientation of chromosomes on the mitotic or meiotic spindle, and is thus an essential prerequisite for chromosome segregation. Cohesion is mediated by cohesin complexes that are thought to embrace sister chromatids as large rings. Cohesin binds to DNA dynamically before DNA replication and is converted into a stably DNA-bound form during replication. This conversion requires acetylation of cohesin, which in vertebrates leads to recruitment of sororin. Sororin antagonizes Wapl, a protein that is able to release cohesin from DNA, presumably by opening the cohesin ring. Inhibition of Wapl by sororin therefore “locks” cohesin rings on DNA and allows them to maintain cohesion for long periods of time in mammalian oocytes, possibly for months or even years. PMID:23043155

Peters, Jan-Michael; Nishiyama, Tomoko

2012-01-01

23

Sister kinetochores are mechanically fused during meiosis I in yeast.  

PubMed

Production of healthy gametes requires a reductional meiosis I division in which replicated sister chromatids comigrate, rather than separate as in mitosis or meiosis II. Fusion of sister kinetochores during meiosis I may underlie sister chromatid comigration in diverse organisms, but direct evidence for such fusion has been lacking. We used laser trapping and quantitative fluorescence microscopy to study native kinetochore particles isolated from yeast. Meiosis I kinetochores formed stronger attachments and carried more microtubule-binding elements than kinetochores isolated from cells in mitosis or meiosis II. The meiosis I-specific monopolin complex was both necessary and sufficient to drive these modifications. Thus, kinetochore fusion directs sister chromatid comigration, a conserved feature of meiosis that is fundamental to Mendelian inheritance. PMID:25213378

Sarangapani, Krishna K; Duro, Eris; Deng, Yi; Alves, Flavia de Lima; Ye, Qiaozhen; Opoku, Kwaku N; Ceto, Steven; Rappsilber, Juri; Corbett, Kevin D; Biggins, Sue; Marston, Adčle L; Asbury, Charles L

2014-10-10

24

Sister kinetochores are mechanically fused during meiosis I in yeast  

PubMed Central

Production of healthy gametes requires a reductional meiosis I division in which replicated sister chromatids co-migrate, rather than separating as in mitosis or meiosis II. Fusion of sister kinetochores during meiosis I may underlie sister chromatid co-migration in diverse organisms, but direct evidence for such fusion has been lacking. Here we studied native kinetochore particles isolated from yeast using laser trapping and quantitative fluorescence microscopy. Meiosis I kinetochores formed stronger attachments and carried more microtubule-binding elements than kinetochores isolated from cells in mitosis or meiosis II. The meiosis I-specific monopolin complex was both necessary and sufficient to drive these modifications. Thus, kinetochore fusion directs sister chromatid co-migration, a conserved feature of meiosis that is fundamental to Mendelian inheritance. PMID:25213378

Sarangapani, Krishna K.; Duro, Eris; Deng, Yi; Alves, Flavia de Lima; Ye, Qiaozhen; Opoku, Kwaku N.; Ceto, Steven; Rappsilber, Juri; Corbett, Kevin D.; Biggins, Sue; Marston, Adčle L.; Asbury, Charles L.

2014-01-01

25

Synaesthesia: A Case Study of Discordant Monozygotic Twins  

Microsoft Academic Search

We describe a study of 11-year-old twin sisters who are physically identical in appearance but who have considerably different conscious experiences. One twin appears to be a synaesthete in that she states that she has specific colour experiences (i.e. photisms) whenever she views, hears or thinks of digits. The other twin does not report such conscious experiences when viewing, hearing

D. Smilek; B. A. Moffatt; J. Pasternak; B. N. White; M. J. Dixon Dixon; P. M. Merikle

2002-01-01

26

Deformation twinning  

Microsoft Academic Search

The concepts of twinning shears and twinning modes are introduced. The early attempts to predict these features are presented. This is followed by a detailed discussion of the formal theories of Bilby and Crocker and Bevis and Crocker for predicting these elements. Their formalisms are applied to predict twinning modes in single lattice structures, superlattices, hexagonal close packed structure and

J. W. Christian; S. Mahajan

1995-01-01

27

[Sister Tereza Notarnicola].  

PubMed

This paper aims at identifying the motivations which moved Sister Tereza toward nursing and her insertion into Brazilian Nursing Association contributing to disseminate her history as an example of professional life and dedication to nursing. This is a social-historical study based on historical-methodological reference approach of Oral History of Life for data collection. Sister Tereza worked over 33 years for the benefit of all nurses. During this period she contributed to build up the national headquarter of the Association, in Brasilia, not only collecting resources through several raising funds campaigns, but also administering the construction itself. She also was executive secretary of the Association for many years and worked with all main nurse-leaders and pioneers of the country, organizing national congresses, conferences and other scientific events. All nurses are in debt to this notable nursing figure, who at the age of 86, continues working in a nursing home caring old people. She is a living legend and model for young nurses. PMID:17469483

Oguisso, Taka; de Freitas, Genival Fernandes

2006-01-01

28

Sister-sister incest: data from an anonymous computerized survey.  

PubMed

Retrospective data were entered anonymously by 1,521 adult women using a computer-assisted self-interview. Thirty-one participants were victims of sister-sister incest, 40 were victims of brother-sister incest, 19 were victims of father-daughter incest, 8 were victims of sexual abuse by an adult female (including one mother), and 232 were victims of sexual abuse by an adult male other than their father before reaching 18 years of age. The rest (1,203) served as controls. The victims of sister-sister incest had significantly more problematic outcomes than controls on many measures as adults. Victims of sister-sister incest were more depressed and more likely than controls to be distant from the perpetrator-sister and to have traded sex for money, experienced an unplanned pregnancy, engaged in four different types of masturbation, and engaged in 13 different same-sex behaviors. Our findings were consistent with other reports of early eroticization and persistent hypereroticization of incest victims. PMID:23924178

Stroebel, Sandra S; O'Keefe, Stephen L; Griffee, Karen; Kuo, Shih-Ya; Beard, Keith W; Kommor, Martin J

2013-01-01

29

Sister Cities International  

NSDL National Science Digital Library

People from around the world have sought to establish links with other individuals from different nations, and since 1956, cities have sought to also establish meaningful relationships with other urban areas through the Sister Cities International organization. Currently, the organization represents more than 2,500 communities in 126 countries. Visitors to the site can learn which cities are currently seeking partnerships with other cities, read about the organization's annual conference, and also read about the programs they administer. Also, its calendar of events is quite full with programs designed for the general public, such as those dealing with relationships with countries in the Middle East and the question of local government. Finally, the material on the site is available in a number of different languages, including French, German, Spanish, and Japanese.

30

The adverse prognostic hallmarks in identical twins with Langerhans cell histiocytosis: a clinical report and literature review.  

PubMed

Langerhans cell histiocytosis (LCH) is characterized by uncontrolled proliferation of Langerhans cells accompanying eosinophils. It often attacks children under 10 years of age. LCH in identical twins is very rare and its prognosis is different. Here we report identical-twin sisters with LCH. Computed tomography (CT) revealed osteolytic change in each twin's skull, and the elder exhibited poor eyesight. There were massive histiocyte-like cells surrounded by eosinophils in pathologic specimen of the abnormal lesions, which is typical pathologic finding in LCH. These pathologic cells were positive for S-100 and the cell surface protein CD1 antigen (CD1?), the known markers of LCH. After treating them with surgery, no symptoms were seen in the younger until now. While the older was found another soft mass (about 2.0 cm in diameter) in the left temporal area 18 months later. The same treatment was given to the older after admission, and she is healthy to date. To explore the relationship between hallmarks and the prognosis of identical-twin patients with LCH, we retrieved the 16 literatures (16 identical-twin pairs, 31 patients) listed in PubMed during the past 60 years. The data revealed all those patients who have disseminated to the bone marrow, spleen and liver with symptoms of fever and hepatosplenomegaly exhibited worse prognosis (9 out of the 31 patients). The other identical-twin subjects without infiltration of those organs recovered well. In conclusion, this study reveals the adverse hallmarks of prognosis in identical-twin patients with LCH by reviewing relevant literatures. PMID:23924960

Chai, Damin; Tao, Yisheng; Bao, Zhengqi; Yang, Li; Feng, Zhenzhong; Ma, Li; Liang, Limei; Zhou, Xinwen

2013-01-01

31

Twin-to-twin transfusion syndrome  

MedlinePLUS

Twin-to-twin transfusion syndrome (TTTS) is a rare condition that occurs only in identical twins while they are in the womb. ... TTTS occurs when the blood supply of one twin moves to the other the shared placenta. The ...

32

Sulcus vocalis in monozygotic twins.  

PubMed

Sulcus vocalis is the presence of a groove extending along the vibratory surface of a vocal fold and may result in dysphonia. Depending on the level of severity, this condition may require treatment involving complicated surgical techniques. Cases of sulcus vocalis are classified as physiological, vergeture, or pouch type. A clear explanation of the etiology has not been established, and the currently proposed congenital origin, as described in the literature, remains controversial. This paper presents findings from monozygotic twin sisters with bilateral sulcus vocalis; these patients had similar morphologies, vibratory characteristics, and vocal quality measurements, which support the theory of a congenital etiology. PMID:19427145

Cakir, Zeynep Alkan; Yigit, Ozgur; Kocak, Ismail; Sunter, A Volkan; Dogan, Muzeyyen

2010-04-01

33

Sister chromatid exchanges in barley  

Microsoft Academic Search

A mean frequency of 20.6 sister chromatid exchanges (SCEs) per cell has been observed in a reconstructed karyotype of Hordeum vulgare by application of the FPG technique after unifilar incorporation of BrdU into chromosomes. The involvement in SCEs of the 48 segments into which the chromosome set had been subdivided was, with a single deviation, length proportional and independent of

I. Schubert; G. Künzel; H. Bretschneider; R. Rieger; H. Nicoloff

1980-01-01

34

A Tale of Two Sisters  

ERIC Educational Resources Information Center

How many children benefit in many diverse ways through art and/or design? Their personalities may draw different benefits and attributes, but that attests to its wide scope. This article relates a brief story of two sisters. The author describes how the siblings' different personalities played a role in their success.

Caouette, Ralph

2009-01-01

35

The effects of X monosomy on brain development: monozygotic twins discordant for Turner's syndrome.  

PubMed

Monosomy for the X chromosome is the most frequent cause of Turner's syndrome, a common clinical syndrome associated with particular physical and neurobehavioral features. The results from comprehensive assessment of prepubertal monozygotic female twins discordant for X monosomy are presented. Zygosity was established with DNA Fingerprinting and no evidence of chromosomal mosaicism was seen in either child. Physical features in the affected twin were relatively mild with respect to the full spectrum of physical malformations and disabilities associated with Turner's syndrome. The neurobehavioral phenotypes of the twins were compared. Although both sisters scored in the superior range of intelligence, the affected twin's Performance IQ was 18 points less than her sister, whereas Verbal IQ showed only a 3-point difference between the sisters. Other relative differences were noted within the executive, visuospatial, and visuomotor domains of function. Behavioral evaluation indicated greater problems with attention, hyperactivity, and anxiety in the affected twin. Quantitative analysis of brain anatomy revealed evidence of both general and regional effects of X monosomy on neurodevelopment. Cerebrospinal fluid volume was increased by 25% in the affected twin compared with her sister with a corresponding decrease in gray matter volume. The right frontal, right parietal-occipital, and left parietal-perisylvian regions showed the greatest discrepancy between the sisters with respect to increased cerebrospinal fluid and decreased gray matter volumes in twin with X monosomy. Differences in the posterior fossa were also noted with a 50% relative increase in the volumes of the fourth ventricle and cisterna magna and a 10 to 15% relative reduction in size of the cerebellar vermis, pons, and medulla in the affected twin. The association between the neurobehavioral and neuroanatomical findings in the affected twin is discussed. The unique nature of the naturally occurring genetic phenomenon seen in this twin pair provides an opportunity to more fully elucidate the neurobehavioral phenotype associated with X monosomy and Turner's syndrome. PMID:8517687

Reiss, A L; Freund, L; Plotnick, L; Baumgardner, T; Green, K; Sozer, A C; Reader, M; Boehm, C; Denckla, M B

1993-07-01

36

78 FR 45061 - Safety Zone; Sister Bay Marina Fest Fireworks and Ski Show, Sister Bay, WI  

Federal Register 2010, 2011, 2012, 2013

...Zone; Sister Bay Marina Fest Fireworks and Ski Show, Sister Bay, WI AGENCY: Coast Guard...Sister Bay due to a fireworks display and ski show. This temporary safety zone is necessary...associated with the fireworks display and ski show in Sister Bay on August 31,...

2013-07-26

37

NOVA Online: Titanic's Lost Sister  

NSDL National Science Digital Library

Companion site to an original broadcast on January 28, 1997. When Titanic sank, construction on her sister ship, Britannic, was interrupted so she could be overhauled with new regulations. Britannic sank in 1916 in less than an hour. Includes interview with Robert Ballard, who found the sunken Titanic, an interactive search, and salvage activity. Others resources available: written transcript, teacher's guide, students activities, and links to additional resources.

38

Twin-to-twin transfusion syndrome  

MedlinePLUS Videos and Cool Tools

Twin to Twin Transfusion Syndrome, or TTTS, is a disease of the placenta. This condition affects twins or other multiples that share a single placenta containing blood vessels going from one baby to the other. Blood from the smaller "donor" twin is transferred to the larger " ...

39

Twin Supergravities  

E-print Network

We study the phenomenon that pairs of supergravities can have identical bosonic field content but different fermionic extensions. Such twin theories are classified and shown to originate as truncations of a common theory with more supersymmetry. Moreover, we discuss the possible gaugings and scalar potentials of twin theories. This allows to pinpoint to which extent these structures are determined by the purely bosonic structure of the underlying Kac-Moody algebras and where supersymmetry comes to plays its role. As an example, we analyze the gaugings of the six-dimensional N=(0,1) and N=(2,1) theories with identical bosonic sector and explicitly work out their scalar potentials. The discrepancy between the potentials finds a natural explanation within maximal supergravity, in which both theories may be embedded.

Diederik Roest; Henning Samtleben

2009-07-13

40

Utilizing Twins as Controls for Non-Twin Case-Materials in Genome Wide Association Studies  

PubMed Central

Twin registries around the globe have collected DNA samples from large numbers of monozygotic and dizygotic twins. The twin sample collections are frequently used as controls in disease-specific studies together with non-twins. This approach is unbiased under the hypothesis that twins and singletons are comparable in terms of allele frequencies; i.e. there are no genetic variants associated with being a twin per se. To test this hypothesis we performed a genome-wide association study comparing the allele frequency of 572,352 single nucleotide polymorphisms (SNPs) in 1,413 monozygotic (MZ) and 5,451 dizygotic (DZ) twins with 3,720 healthy singletons. Twins and singletons have been genotyped using the same platform. SNPs showing association with being a twin at P-value < 1 × 10-5 were selected for replication analysis in 1,492 twins (463 MZ and 1,029 DZ) and 1,880 singletons from Finland. No SNPs reached genome-wide significance (P-value < 5 × 10-8) in the main analysis combining MZ and DZ twins. In a secondary analysis including only DZ twins two SNPs (rs2033541 close to ADAMTSL1 and rs4149283 close to ABCA1) were genome-wide significant after meta-analysis with the Finnish population. The estimated proportion of variance on the liability scale explained by all SNPs was 0.08 (P-value=0.003) when MZ and DZ were considered together and smaller for MZ (0.06, P-value=0.10) compared to DZ (0.09, P-value=0.003) when analyzed separately. In conclusion, twins and singletons can be used in genetic studies together with general population samples without introducing large bias. Further research is needed to explore genetic variances associated with DZ twinning. PMID:24340086

Ganna, Andrea; Ortega-Alonso, Alfredo; Havulinna, Aki; Salomaa, Veikko; Kaprio, Jaakko; Pedersen, Nancy L.; Sullivan, Patrick F.; Ingelsson, Erik; Hultman, Christina M.; Magnusson, Patrik K. E.

2013-01-01

41

Brothers, Sisters and Aging Parents  

E-print Network

members are often more familiar with the unique needs of the aging parent than are those outside the family, a family member should coor- dinate the resources of family and community. Determine who the coordinator will be. Viewing caregiving as a shared... strain relationships. Questions may emerge such as ?Who will provide care?? and ?Why should I look after my mother when my sister was the favorite?? Sometimes siblings compete to do the most for the aged parent, quarrel over the best care arrange- ments...

Isbell, Lou

1999-09-02

42

Holocentric plant meiosis: first sisters, then homologues.  

PubMed

Meiosis is a crucial process of sexual reproduction by forming haploid gametes from diploid precursor cells. It involves 2 subsequent divisions (meiosis I and meiosis II) after one initial round of DNA replication. Homologous monocentric chromosomes are separated during the first and sister chromatids during the second meiotic division. The faithful segregation of monocentric chromosomes is realized by mono-orientation of fused sister kinetochores at metaphase I and by bi-orientation of sister kinetochores at metaphase II. Conventionally this depends on a 2-step loss of cohesion, along chromosome arms during meiosis I and at sister centromeres during meiosis II. PMID:25457919

Heckmann, Stefan; Schubert, Veit; Houben, Andreas

2014-12-01

43

Twin SUSY  

E-print Network

We construct an extension of the MSSM in which superpartners can naturally be heavier than the electroweak scale. This ``little hierarchy'' of scales is stable because the Higgs arises as a pseudo-Nambu-Goldstone boson in the breaking of an accidental SU(4) symmetry of the Higgs sector. Supersymmetry and the global symmetry combine to forbid logarithmically divergent one-loop contributions to the Higgs mass. The accidental symmetry follows from a simple ``twin'' parity which exchanges the SU(2) sectors in the SU(3)_C x SU(2)_L x SU(2)_R x U(1)_X gauge group.

Adam Falkowski; Stefan Pokorski; Martin Schmaltz

2006-04-22

44

Monozygotic twins discordant for constitutive BRCA1 promoter methylation, childhood cancer and secondary cancer.  

PubMed

We describe monozygotic twins discordant for childhood leukemia and secondary thyroid carcinoma. We used bisulfite pyrosequencing to compare the constitutive promoter methylation of BRCA1 and several other tumor suppressor genes in primary fibroblasts. The affected twin displayed an increased BRCA1 methylation (12%), compared with her sister (3%). Subsequent bisulfite plasmid sequencing demonstrated that 13% (6 of 47) BRCA1 alleles were fully methylated in the affected twin, whereas her sister displayed only single CpG errors without functional implications. This between-twin methylation difference was also found in irradiated fibroblasts and untreated saliva cells. The BRCA1 epimutation may have originated by an early somatic event in the affected twin: approximately 25% of her body cells derived from different embryonic cell lineages carry one epigenetically inactivated BRCA1 allele. This epimutation was associated with reduced basal protein levels and a higher induction of BRCA1 after DNA damage. In addition, we performed a genome-wide microarray analysis of both sisters and found several copy number variations, i.e., heterozygous deletion and reduced expression of the RSPO3 gene in the affected twin. This monozygotic twin pair represents an impressive example of epigenetic somatic mosaicism, suggesting a role for constitutive epimutations, maybe along with de novo genetic alterations in recurrent tumor development. PMID:22207351

Galetzka, Danuta; Hansmann, Tamara; El Hajj, Nady; Weis, Eva; Irmscher, Benjamin; Ludwig, Marco; Schneider-Rätzke, Brigitte; Kohlschmidt, Nicolai; Beyer, Vera; Bartsch, Oliver; Zechner, Ulrich; Spix, Claudia; Haaf, Thomas

2012-01-01

45

Brahmakumari Sister Shivani Rajyoga Meditation Teacher  

E-print Network

Brahmakumari Sister Shivani Rajyoga Meditation Teacher Brahmakumari Sister Shivani is a Rajyoga Meditation Teacher who has been studying spiritual knowledge and practicing the ancient technique of Rajyoga Meditation, as taught by the Prajapita Brahma Kumaris Ishwariya Vishwa Vidyalaya, Mount Abu, for the past 12

Srivastava, Kumar Vaibhav

46

Twin Jet  

NASA Technical Reports Server (NTRS)

Many subsonic and supersonic vehicles in the current fleet have multiple engines mounted near one another. Some future vehicle concepts may use innovative propulsion systems such as distributed propulsion which will result in multiple jets mounted in close proximity. Engine configurations with multiple jets have the ability to exploit jet-by-jet shielding which may significantly reduce noise. Jet-by-jet shielding is the ability of one jet to shield noise that is emitted by another jet. The sensitivity of jet-by-jet shielding to jet spacing and simulated flight stream Mach number are not well understood. The current experiment investigates the impact of jet spacing, jet operating condition, and flight stream Mach number on the noise radiated from subsonic and supersonic twin jets.

Henderson, Brenda; Bozak, Rick

2010-01-01

47

Sister to Sister: Everyone Has a Heart Foundation  

MedlinePLUS

... Numbers Blood Pressure Diabetes Physical Activity Obesity Stress Smoking Family History Age Heart Fact Sheets (English & Spanish) Healthy Living A step in the right direction - exercising for your heart health Get Screened Eat Heart ... Smoking Medications Girlfriends' Guide to Heart Health Health Tools ...

48

Biamnial alpha fetoprotein concentration in twins, one with multiple malformations.  

PubMed Central

In the 18th week of pregnancy in a 22 year old patient, twins were diagnosed by ultrasound. It was found that one twin had an abnormal skull outline and an echo-free area covered by a thin membrane in the region of the abdomen. The second embryo showed no sign of malformation. Amniocentesis was performed and the AFP in both samples of amniotic fluid were in the pathological range. Our own observations with indirect immunofluorescence confirmed that one twin with defects leading to abnormally high AFP levels can cause pathological AFP levels in the amniotic sac of a healthy twin. Images PMID:6209397

Huber, J; Wagenbichler, P; Bartsch, F

1984-01-01

49

All in the Family: The Sister Study  

MedlinePLUS

Skip Navigation Bar Home Current Issue Past Issues All in the Family: The Sister Study Past Issues / ... that may ultimately eliminate this dreaded disease. We all know that breast cancer does not discriminate. Whether ...

50

Staging of Twin-Twin Transfusion Syndrome  

Microsoft Academic Search

OBJECTIVE:The purpose of this study was to evaluate the prognostic value of sonographic and clinical parameters to develop a staging classification of twin-twin transfusion syndrome (TTTS).STUDY DESIGN:Severe TTTS was defined as the presence of polyhydramnios (maximum vertical pocket of ?8 cm) and oligohydramnios (maximum vertical pocket of ?2 cm). Nonvisualization of the bladder in the donor twin (?BDT) and absence

Rubén A Quintero; Walter J Morales; Mary H Allen; Patricia W Bornick; Patricia K Johnson; Michael Kruger

1999-01-01

51

Eruptive history of South Sister, Oregon Cascades  

USGS Publications Warehouse

South Sister is southernmost and highest of the Three Sisters, three geologically dissimilar stratovolcanoes that together form a spectacular 20km reach along the Cascade crest in Oregon. North Sister is a monotonously mafic edifice as old as middle Pleistocene, Middle Sister a basalt-andesite-dacite cone built between 48 and 14ka, and South Sister is a basalt-free edifice that alternated rhyolitic and intermediate modes from 50ka to 2ka (largely contemporaneous with Middle Sister). Detailed mapping, 330 chemical analyses, and 42 radioisotopic ages show that the oldest exposed South Sister lavas were initially rhyolitic ~50ka. By ~37ka, rhyolitic lava flows and domes (72-74% SiO2) began alternating with radially emplaced dacite (63-68% SiO2) and andesite (59-63% SiO2) lava flows. Construction of a broad cone of silicic andesite-dacite (61-64% SiO2) culminated ~30ka in a dominantly explosive sequence that began with crater-forming andesitic eruptions that left fragmental deposits at least 200m thick. This was followed at ~27ka by growth of a steeply dipping summit cone of agglutinate-dominated andesite (56-60.5% SiO2) and formation of a summit crater ~800m wide. This crater was soon filled and overtopped by a thick dacite lava flow and then by >150m of dacitic pyroclastic ejecta. Small-volume dacite lavas (63-67% SiO2) locally cap the pyroclastic pile. A final sheet of mafic agglutinate (54-56% SiO2) - the most mafic product of South Sister - erupted from and drapes the small (300-m-wide) present-day summit crater, ending a summit-building sequence that lasted until ~22ka. A 20kyr-long-hiatus was broken by rhyolite eruptions that produced (1) the Rock Mesa coulee, tephra, and satellite domelets (73.5% SiO2) and (2) the Devils Chain of ~20 domes and short coulees (72.3-72.8% SiO2) from N-S vent alignments on South Sister's flanks. The compositional reversal from mafic summit agglutinate to recent rhyolites epitomizes the frequently changing compositional modes of the South Sister locus throughout its lifetime. South Sister is part of a reach of the Cascades unusually active in the last 50kyr, characterized by high vent density, N-S vent alignments, and numerous eruptive units of true rhyolite (? 72% SiO2) that distinguishes it from much of the Quaternary Cascade arc; these are eruptive expressions of the complex confluence of arc and intraplate magmatic-tectonic regimes.

Fierstein, J.; Hildreth, W.; Calvert, A.T.

2011-01-01

52

The Amoeba Sisters YouTube Videos  

NSDL National Science Digital Library

The Amoeba Sisters strive to facilitate curiosity and engagement by making biology both humorous and meaningful. The videos use real world examples and silly cartoons to demystify difficult biology concepts, such as cell anatomy, homeostasis, enzymes, and biomolecules. A new video is released weekly. The creators are sisters who both work in education. One is a high school biology teacher who found these videos made biology more approachable and easier to comprehend.

Sisters, The A.

2014-04-04

53

Acoustic analysis of intentional vocalizations by autistic and non-autistic monozygotic twins  

E-print Network

).This study examine the cries of a young infant who is later diagnosed with autism. Her cries will be compared with those of her identical twin sister who does not later get diagnosed with autism. Trevarthen and Daniel (2005) have used home video tapes...

Scoular, Claire

2008-12-04

54

Responsiveness to exercise training in juvenile dermatomyositis: a twin case study  

Microsoft Academic Search

BACKGROUND: Patients with juvenile dermatomyositis (JDM) often present strong exercise intolerance and muscle weakness. However, the role of exercise training in this disease has not been investigated. PURPOSE: this longitudinal case study reports on the effects of exercise training on a 7-year-old patient with JDM and on her unaffected monozygotic twin sister, who served as a control. METHODS: Both the

Clarissa Omori; Danilo ML Prado; Bruno Gualano; Adriana ME Sallum; Ana L Sá-Pinto; Maria B Perondi; Clovis AA Silva

2010-01-01

55

Twin Prime Sieve  

E-print Network

A sieve is constructed for ordinary twin primes of the form 6m+/-1 that are characterized by their twin rank m. It has no parity problem. Non-rank numbers are identified and counted using odd primes p>=5. Twin- and non-ranks make up the set of positive integers. Regularities of non-ranks allow gathering information on them to obtain a Legendre-type formula for the number of twin-ranks near primorial arguments.

H. J. Weber

2012-03-23

56

Deformation twins in Hornblende  

USGS Publications Warehouse

Hornblende deformation twins with twin planes parallel to (101) are produced experimentally in single crystals by compression parallel to the c axis. Twinning occurs at confining pressures from 5 to 15 kilobars and temperatures from 400?? to 600??C (strain rate, 10-5 per second).

Rooney, T.P.; Riecker, R.E.; Ross, M.

1970-01-01

57

Severe infections in twins.  

PubMed

We describe 4 sets of twins 5 days to 10 weeks of age with a serious bacterial or viral infection. The issue of the occurrence of a simultaneous infection in twins and the clinical dilemma of the appropriate evaluation and treatment of an asymptomatic co-twin of infants with a serious infection is discussed. PMID:23376941

Erez, Daniella Levy; Grisaru-Soen, Galia; Ashkenazi-Hoffnung, Liat; Yarden-Bilavsky, Havatzelet; Amir, Jacob; Bilavsky, Efraim

2013-07-01

58

Genetics and Twins  

Microsoft Academic Search

The phenomenon of twinning has fascinated scientists and others over the centuries. A twin pregnancy has a higher risk of fetal morbidity and mortality than a singleton pregnancy depending on the zygosity and chorionicity of the fetuses. Dizygotic twins originate from two separate ova that are fertilized by two different sperm and are no more alike than any two siblings,

Cindy M. Little

2011-01-01

59

Examination of the twin placenta.  

PubMed

Twin birth rates have increased dramatically over the past three decades, and twins currently account for 3% of all pregnancies. Twin pregnancies of any type are at risk for prematurity. In addition, monochorionic twin pregnancies (25-30% of all twin pregnancies) are predisposed to a specific set of complications, including twin-to-twin transfusion syndrome (TTTS), twin reversed arterial perfusion syndrome (TRAP), malformations, and intertwin growth discordance. This article reviews the basic mechanisms underlying the twinning process, the relationship between zygosity and chorionicity, and the various types of twinning. We describe the major complications of monochorionic twinning in association with their reported placental characteristics (or lack thereof). Finally, a rational, evidence-based approach to examination of the twin placenta is presented. It is essential for the pathologist to understand the value, strengths, and limitations of examination of the twin placenta in order to provide a meaningful clinicopathological correlation in complicated (monochorionic) twin pregnancies. PMID:25455620

Paepe, Monique E De

2015-02-01

60

Twin Paradox Program  

NSDL National Science Digital Library

The Twin Paradox program displays the effect of time dilation on a moving twin as seen from a stationary twin. In the default scenario the light signals sent from the moving twin are depicted using a spacetime diagram and are shown as seen in the stationary twinâs reference frame (the Home Frame). The sliders can be used to change the twinâs trip distance and her trip speed relative to the stationary twin. Twin Paradox is an Open Source Physics program written for the teaching of special relativity. It is distributed as a ready-to-run (compiled) Java archive. Double clicking the sr_twin.jar file will run the program if Java is installed. Other special relativity programs are also available. They can be found by searching ComPADRE for Open Source Physics, OSP, or Relativity.

Simov, Kiril; Christian, Wolfgang

2008-05-30

61

QUANTITATIVE GENETIC MODELING OF LATERAL VENTRICULAR SHAPE AND VOLUME USING MULTI-ATLAS FLUID IMAGE ALIGNMENT IN TWINS  

E-print Network

ALIGNMENT IN TWINS Yi-Yu Chou1 , Natasha Leporé1 , Marina Barysheva1 , Ming-Chang Chiang1 , Katie McMahon2 Image Alignment") to fluidly propagate hand-labeled parameterized surface meshes into 116 scans of twins of MRI scans from healthy individuals with known genetic resemblance (e.g., twins). Genetic models can

Thompson, Paul

62

137. TWIN FALLS SOUTH SIDE MAIN CANAL DIVERSION HEADGATES, TWIN ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

137. TWIN FALLS SOUTH SIDE MAIN CANAL DIVERSION HEADGATES, TWIN FALLS COUNTY, MILNER, IDAHO; OVERALL VIEW OF MAIN HEADGATES, DAM IN BACKGROUND. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

63

147. TWIN FALLS MAIN CANAL DIVERSION, TWIN FALLS COUNTY, MILNER, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

147. TWIN FALLS MAIN CANAL DIVERSION, TWIN FALLS COUNTY, MILNER, IDAHO; VIEW OF MAIN HEADGATES, EAST VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

64

141. TWIN FALLS MAIN CANAL DIVERSION, TWIN FALLS COUNTY, MILNER, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

141. TWIN FALLS MAIN CANAL DIVERSION, TWIN FALLS COUNTY, MILNER, IDAHO; CLOSE-UP OF MAIN HEADGATES, RADIAL GATES INSIDE, SOUTHEAST VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

65

148. TWIN FALLS MAIN CANAL DIVERSION, TWIN FALLS COUNTY, MILNER ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

148. TWIN FALLS MAIN CANAL DIVERSION, TWIN FALLS COUNTY, MILNER DAM; HEADGATES AT INLET, SOUTHWEST VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

66

149. TWIN FALLS MAIN CANAL DIVERSION, TWIN FALLS COUNTY, MILNER ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

149. TWIN FALLS MAIN CANAL DIVERSION, TWIN FALLS COUNTY, MILNER DAM; CLOSE-UP OF MAIN CANAL GATES, SOUTH VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

67

97. POINT SPILL, TWIN FALLS MAIN CANAL, TWIN FALLS COUNTY ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

97. POINT SPILL, TWIN FALLS MAIN CANAL, TWIN FALLS COUNTY NORTHWEST OF MURTAUGH, IDAHO; OVERALL WEST VIEW FROM CANAL SIDE. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

68

98. SHOESTRING, TWIN FALLS MAIN CANAL, TWIN FALLS COUNTY NORTHWEST ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

98. SHOESTRING, TWIN FALLS MAIN CANAL, TWIN FALLS COUNTY NORTHWEST OF MURTAUGH, IDAHO; PROFILE VIEW, SOUTH. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

69

99. POINT SPILL, TWIN FALLS MAIN CANAL, TWIN FALLS COUNTY ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

99. POINT SPILL, TWIN FALLS MAIN CANAL, TWIN FALLS COUNTY NORTHWEST OF MURTAUGH, IDAHO; CLOSE-UP OF OUTLET SIDE OF GATES, SOUTH VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

70

CELL CYCLE: The Difficulty in Separating Sisters  

NSDL National Science Digital Library

Access to the article is free, however registration and sign-in are required. The separation of the tightly associated sister chromatids during the anaphase step of cell division is an intricately orchestrated event. Orr-Weaver, in her Perspective, discusses new findings by Zou et al. in this issue that reveal the underlying molecular machinery involved.

Terry L. Orr-Weaver (Whitehead Institute and the Massachusetts Institute of Technology;)

1999-07-16

71

INTRODUCTION Mitotic metaphase chromosomes show sister chromatids  

E-print Network

. Meiosis I bivalents, as mitotic chromosomes, show sister-chromatid centromere and arm cohesions cohesion during meiosis I, and then release centromere cohesion during meiosis II (for review see Moore and Orr- Weaver, 1998). Consequently, this sequential loss of cohesion during meiosis might be precisely

Villefranche sur mer

72

SISTER CHROMATID EXCHANGES IN MAMMALIAN MEIOTIC CHROMOSOMES  

EPA Science Inventory

Very little is known about sister chromatid exchanges (SCEs) in meiotic cells--only that they occur (1) and reveal frequency and distribution patterns apparently unaffected by cross-over (CO) exchange conditions in those cells; (2) unfortunately, the number of studies from which ...

73

46 CFR 116.210 - Plans for sister vessels.  

Code of Federal Regulations, 2010 CFR

...2010-10-01 false Plans for sister vessels. 116.210 Section 116.210 Shipping COAST GUARD, DEPARTMENT OF HOMELAND...PASSENGERS CONSTRUCTION AND ARRANGEMENT Plans § 116.210 Plans for sister vessels. (a) Plans...

2010-10-01

74

Splitting the Chromosome: Cutting the Ties That Bind Sister Chromatids  

NSDL National Science Digital Library

In eukaryotic cells, sister DNA molecules remain physically connected from their production at S phase until their separation during anaphase. This cohesion is essential for the separation of sister chromatids to opposite poles of the cell at mitosis. It also permits chromosome segregation to take place long after duplication has been completed. Recent work has identified a multisubunit complex called cohesin that is essential for connecting sisters. Proteolytic cleavage of one of cohesin's subunits may trigger sister separation at the onset of anaphase.

Kim Nasmyth (Research Institute of Molecular Pathology ;); Jan-Michael Peters (Research Institute of Molecular Pathology ;); Frank Uhlmann (Research Institute of Molecular Pathology ;)

2000-05-26

75

Twinning zones in crystals  

NASA Astrophysics Data System (ADS)

We have investigated the kinetics of twinning in diphenyl crystals and the external morphology of diphenyl, quartz and flourphlogopite crystals. It has been shown that under definite crystallization temperature, interval of supercooling of melts and supersaturation of vapour or solutions, a zone of faces forms on crystals. Over these faces individual crystals grow in the twinned orientation. The growth twinning is epitaxial in nature. Twinning epitaxy is a widely popular phenomena in natural and synthetic crystals. The primary inclusions are responsible for the self-reorientationof the crystals obtained by Czochralski and directional crystallization methods.

Koslova, O. G.; Dukova, E. D.; Orlova, A. O.

1983-10-01

76

Twins, Triplets, and Other Multiples  

MedlinePLUS

... two. Identical twins look almost exactly alike and share the exact same genes. Most identical twins happen by chance. Fraternal ... by two, separate sperm. Fraternal twins do not share the exact same genes — they are no more alike than they ...

77

Crocodile Talk: Attributions of Incestuously Abused and Nonabused Sisters.  

ERIC Educational Resources Information Center

This qualitative study analyzed the retrospective attributions of adult sisters (five abused sister dyads, and five abused and nonabused sister dyads) who grew up in incestuous families. It examined the attributions of subjects regarding the general sibling group; victim selection and nonselection; and attributions regarding jealousy, protection,…

Monahan, Kathleen

1997-01-01

78

X-ray- and TEM-induced mitotic recombination in Drosophila melanogaster: unequal and sister-strand recombination.  

PubMed

Twin mosaic spots of dark-apricot and light-apricot ommatidia were found in the eyes of wa/wa females, of wa males, of females homozygous for In(1)sc4, wa and of attached-X females homozygous for wa. The flies were raised from larvae which had been treated with 1630 R of X-rays at the age of 48-52 hours. An additional group of wa/wa females and wa males came from larvae that had been fed with triethylene melamine (TEM) at the age of 22-24 hours. The twin spots apparently were the result of induced unequal mitotic recombination, i.e. from unequal sister-strand recombination in the males and from unequal sister-strand recombination as well as, possibly, unequal recombination between homologous strands in the females. That is, a duplication resulted in waDp wa/wa dark-apricot ommatidia and the corresponding deficiency in an adjacent area of wa/Df wa light-apricot ommatidia. In an additional experiment sister-strand mitotic recombination in the ring-X chromosome of ring-X/rod-X females heterozygous for w and wco is believed to be the cause for X-ray induced single mosaic spots that show the phenotype of the rod-X marker. PMID:810661

Becker, H J

1975-01-01

79

Monozygotic twins discordant for trisomy 13: counselling and management issues.  

PubMed

The diagnosis and management of a heterokaryotypic monochorionic pregnancy, in which one of twins had trisomy 13, is presented. Monozygosity and discordant karyotypes were confirmed by amniocentesis of both the sacs. Radiofrequency ablation of the trisomic twin was successfully performed at 18-weeks gestation and the pregnancy ended at term with the birth of a healthy girl who remains well on follow-up at 12 months of age. We reiterate the importance of early amniocentesis of both the sacs in the presence of discordant fetal abnormalities and consideration of selective fetal termination to optimise the outcome of heterokaryotypic monochorionic twin pregnancies. PMID:22842802

Dixit, A; Tanteles, G; Ocraft, K; McEwan, A; Sarkar, A

2012-08-01

80

Monozygotic twins with 17q21.31 microdeletion syndrome.  

PubMed

Chromosome 17q21.31 microdeletion syndrome is a genomic disorder caused by a recurrent 600 kb long deletion. The deletion affects the region of a common inversion present in about 20% of Europeans. The inversion is associated with the H2 haplotype carrying additional low-copy repeats susceptible to non-allelic homologous recombination, and this haplotype is prone to deletion. No instances of 17q21.31 deletions inherited from an affected parent have been reported, and the deletions always affected a parental chromosome with the H2 haplotype. The syndrome is characterized clinically by intellectual disability, hypotonia, friendly behavior and specific facial dysmorphism with long face, large tubular or pear-shaped nose and bulbous nasal tip. We present monozygotic twin sisters showing the typical clinical picture of the syndrome. The phenotype of the sisters was very similar, with a slightly more severe presentation in Twin B. The 17q21.31 microdeletion was confirmed in both patients but in neither of their parents. Potential copy number differences between the genomes of the twins were subsequently searched using high-resolution single nucleotide polymorphism (SNP) and comparative genome hybridisation (CGH) arrays. However, these analyses identified no additional aberrations or genomic differences that could potentially be responsible for the subtle phenotypic differences. These could possibly be related to the more severe perinatal history of Twin B, or to the variable expressivity of the disorder. In accord with the expectations, one of the parents (the mother) was shown to carry the H2 haplotype, and the maternal allele of chromosome 17q21.31 was missing in the twins. PMID:24909117

Vlckova, Marketa; Hancarova, Miroslava; Drabova, Jana; Slamova, Zuzana; Koudova, Monika; Alanova, Renata; Mannik, Katrin; Kurg, Ants; Sedlacek, Zdenek

2014-10-01

81

Childbirth, hospitalisation and sickness absence: a study of female twins  

PubMed Central

Objective To investigate associations of giving birth with morbidity in terms of hospitalisation and social consequences of morbidity in terms of sickness absence (SA), while taking familial (genetics and shared environmental) factors into account. Design Prospective register-based cohort study. Estimates of risk of hospitalisation and SA were calculated as HRs with 95% CIs. Setting All female twins, that is, women with a twin sister, born in Sweden. Participants 5118 Swedish female twins (women with a twin sister), born during 1959–1990, where at least one in the twin pair had their first childbirth (T0) during 1994–2009 and none gave birth before 1994. Main outcome measures Hospitalisation and SA during year 3–5 after first delivery or equivalent. Results Preceding the first childbirth, the mean annual number of SA days increased for mothers, and then decreased again. Hospitalisation after T0 was associated with higher HRs of short-term and long-term SA (HR for short-term SA 3.0; 95% CI 2.5 to 3.6 and for long-term SA 2.3; 95% CI 1.6 to 3.2). Hospitalisation both before and after first childbirth was associated with a higher risk of future SA (HR for long-term SA 4.2; 95% CI 2.7 to 6.4). Familial factors influenced the association between hospitalisation and long-term SA, regardless of childbirth status. Conclusions Women giving birth did not have a higher risk for SA than those not giving birth and results indicate a positive health selection into giving birth. Mothers hospitalised before and/or after giving birth had higher risks for future SA, that is, there was a strong association between morbidity and future SA. PMID:25573523

Björkenstam, Emma; Alexanderson, Kristina; Narusyte, Jurgita; Kjeldgĺrd, Linnea; Ropponen, Annina; Svedberg, Pia

2015-01-01

82

Papillary thyroid cancer in identical adolescent twins with osteogenesis imperfecta and Hashimoto's thyroiditis: is there a genetic link?  

PubMed

The relationship between Hashimoto's thyroiditis (HT) and papillary thyroid cancer (PTC) remains controversial. Researchers have identified multiple genes that could put patients with HT at risk for PTC. None are related to osteogenesis imperfecta (OI). We present identical twin sisters with OI who developed PTC in the setting HT. PMID:25197868

Diegidio, Paul; Kolok, Damon; Brown, Whitney; Camps, Juan I

2014-09-01

83

Placental pathophysiology of the twin oligohydramnios-polyhydramnios sequence and the twin-twin transfusion syndrome  

Microsoft Academic Search

Currently accepted sonographic criteria for antenatal diagnosis of twin-twin transfusion (TTT) syndrome include a monochorionic placenta with same-sex twins, marked growth discordance, and oligohydramnios of the growth-retarded twin with coexistent polyhydramnios of the larger twin. Our previous report of nine women fulfilling these criteria, examined using sequential funipuncture of both fetuses, demonstrated inter-twin blood transfusion in only four cases (44

J. P. Bruner; T. L. Anderson; R. L. Rosemond

1998-01-01

84

Twins and endocrinology  

PubMed Central

Twins are two independent babies delivered during the same pregnancy and are divided as monozygotic or dizygotic based on their origin. Dizygotic twins are similar to two siblings and have different genetic information. In contrary, monozygotic twins have a similar genetic identity and provide a unique opportunity to evaluate the contribution of genetic and environmental factors of the disease. The endocrine and metabolic disorders affect a large number of the population including the twins. Diabetes, obesity, and autoimmune thyroid disease are the most common endocrine disorders in general practice. It is essential to understand the genetic basis of endocrine disorders for therapy, prognostication and risk assessment for future generations. In this article, we review the endocrine disorders in relation to their occurrence in monozygotic twins to highlight the genetic and environmental contribution.

Hari Kumar, K. V. S.; Modi, K. D.

2014-01-01

85

Coherent Twinning Phenomena: Towards Twinning Superlattices in III-V  

E-print Network

Coherent Twinning Phenomena: Towards Twinning Superlattices in III-V Semiconducting Nanowires Qihua an additional series of diffraction peaks consistent with a quasiperiodic placement of twinning boundaries along.e., the distance between twin boundaries, has been found to depend on the temperature gradient imposed

Xiong, Qihua

86

Evil twins alternate with odious twins Chris Bernhardt  

E-print Network

Evil twins alternate with odious twins Chris Bernhardt Fairfield University Fairfield, CT 06824 are odious. Next we say that if two consecutive integers are evil then this is a pair of evil twins and that if two consecutive integers are odious then this is a pair of odious twins. Returning to the integers

Bernhardt, Chris

87

PTX3 genetic variation and dizygotic twinning in the Gambia: could pleiotropy with innate immunity explain common dizygotic twinning in Africa?  

PubMed

Dizygotic (DZ) twinning has a genetic component and is common among sub-Saharan Africans; in The Gambia its frequency is up to 3% of live births. Variation in PTX3, encoding Pentraxin 3, a soluble pattern recognition receptor that plays an important role both in innate immunity and in female fertility, has been associated with resistance to Mycobacterium tuberculosis pulmonary disease and to Pseudomonas aeruginosa infection in cystic fibrosis patients. We tested whether PTX3 variants in Gambian women associate with DZ twinning, by genotyping five PTX3 single nucleotide polymorphisms (SNPs) in 130 sister pairs (96 full sibs and 34 half sibs) who had DZ twins. Two, three and five SNP haplotypes differed in frequency between twinning mothers and those without a history of twinning (from P = 0.006 to 3.03e-06 for two SNP and three SNP haplotypes, respectively). Twinning mothers and West African tuberculosis-controls from a previous study shared several frequent haplotypes. Most importantly, our data are consistent with an independently reported association of PTX3 and female fertility in a sample from Ghana. Taken together, these results indicate that selective pressure on PTX3 variants that affect the innate immune response to infectious agents, could also produce the observed high incidence of DZ twinning in Gambians. PMID:22834944

Sirugo, Giorgio; Edwards, Digna R Velez; Ryckman, Kelli K; Bisseye, Cyrille; White, Marquitta J; Kebbeh, Bunja; Morris, Gerard A J; Adegbola, Richard A; Tacconelli, Alessandra; Predazzi, Irene M; Novelli, Giuseppe; Vannberg, Fredrik O; Odunsi, Kunle; Page, Grier P; Williams, Scott M

2012-11-01

88

Road salt turning Twin Cities lakes into dead seas By JOSEPHINE MARCOTTY, Star Tribune  

E-print Network

Road salt turning Twin Cities lakes into dead seas By JOSEPHINE MARCOTTY, Star Tribune March 23 in lakes and streams around the Twin Cities -- road salt. The fish, bugs and other wildlife that live, a primary ingredient in salt, and what it will take to keep urban waters healthy. But the far more difficult

Minnesota, University of

89

Nanoscale Twins Formed by Plastic  

E-print Network

Nanoscale Twins Formed by Plastic Accommodations in Nano Bainite Hung-Wei Yen Hsiao-Tzu Chang Jer. #12;Coherent TBs Strengthening Metals · Nano Twins with coherent grain boundary has been reported). 0 20 40 60 80 100 #12;Twinning in Steels · Twinning in steels can be achieved by several different

Cambridge, University of

90

Classical twin studies and beyond  

Microsoft Academic Search

Twin studies have been a valuable source of information about the genetic basis of complex traits. To maximize the potential of twin studies, large, worldwide registers of data on twins and their relatives have been established. Here, we provide an overview of the current resources for twin research. These can be used to obtain insights into the genetic epidemiology of

Andreas Busjahn; Leena Peltonen; Dorret Boomsma

2002-01-01

91

Twin-to-Twin Transfusion Syndrome  

PubMed Central

The twin-to-twin transfusion syndrome (TTS) results from an unbalanced blood supply through placental anastomoses in monochorionic twins. It induces growth restriction, renal tubular dysgenesis, and oliguria in the donor and visceromegaly and polyuria in the recipient. A better understanding of its pathophysiology could contribute to improving the management of TTS, which still carries a high perinatal mortality in both twins. As well as several other candidates, the renin-angiotensin system might be involved in TTS. To evaluate its role in the pathogenesis of the syndrome, we studied the kidneys of 21 twin pairs who died from TTS at 19 to 30 weeks, compared with 39 individuals in a control group, using light microscopy, immunohistochemistry, and in situ hybridization. The overexpression of the renin protein and transcript with frequent evidence of renin synthesis by mesangial cells was observed in the donor kidneys, presumably as a consequence of chronic renal hypoperfusion. This upregulation of renin synthesis might be beneficial to restore euvolemia. In severe cases of TTS, however, angiotensin-II-induced vasoconstriction acts as an additional deleterious factor by further reducing the renal blood flow in donors. In recipients, renin expression was virtually absent, possibly because it was down-regulated by hypervolemia. However, in addition to congestion and hemorrhagic infarction, there were severe glomerular and arterial lesions resembling those observed in polycythemia- or hypertension-induced microangiopathy. We speculate that fetal hypertension in the recipient might be partly mediated by the transfer of circulating renin produced by the donor, through the placental vascular shunts. PMID:10666392

Mahieu-Caputo, Dominique; Dommergues, Marc; Delezoide, Anne-Lise; Lacoste, Mireille; Cai, Yi; Narcy, Françoise; Jolly, Dominique; Gonzales, Marie; Dumez, Yves; Gubler, Marie-Claire

2000-01-01

92

BRAIN MORPHOLOGY IN TWINS DISCORDANT FOR BIPOLAR DISORDER Van Erp, T.G.M., Thompson, P.M., Kiesepp, T., Tran, H.L., Correll, C.M.,  

E-print Network

BRAIN MORPHOLOGY IN TWINS DISCORDANT FOR BIPOLAR DISORDER Van Erp, T.G.M., Thompson, P.M., Kieseppä disorder, but their etiology remains unresolved. Bipolar disorder is influenced by both genetic) based study, examining 24 twins with bipolar disorder, 15 of their healthy co-twins, and 27 control

Thompson, Paul

93

Sister Mary Emil Penet, I.H.M.: Founder of the Sister Formation Conference  

ERIC Educational Resources Information Center

Mary Emil Penet, I.H.M., (1916-2001) used her talents and charisma to shape the first national organization of American women religious, the Sister Formation Conference (SFC; 1954-1964), facilitating the integrated intellectual, spiritual, psychological, and professional development of vowed women religious. In the decade preceding Vatican II, her…

Glisky, Joan

2006-01-01

94

Anthropometry, carbohydrate and lipid metabolism in the East Flanders Prospective Twin Survey: heritabilities  

Microsoft Academic Search

Aims\\/hypothesis  We determined the genetic contribution of 18 anthropometric and metabolic risk factors of type 2 diabetes using a young healthy\\u000a twin population.\\u000a \\u000a \\u000a \\u000a Methods  Traits were measured in 240 monozygotic (MZ) and 138 dizygotic (DZ) twin pairs aged 18 to 34 years. Twins were recruited from\\u000a the Belgian population-based East Flanders Prospective Twin Survey, which is characterised by its accurate zygosity determination\\u000a and

N. Y. Souren; A. D. C. Paulussen; R. J. F. Loos; M. Gielen; G. Beunen; R. Fagard; C. Derom; R. Vlietinck; M. P. Zeegers

2007-01-01

95

Specific complications of monochorionic twin pregnancies: twin-twin transfusion syndrome and twin reversed arterial perfusion sequence.  

PubMed

Monochorionic twins are subjected to specific complications which originate in either imbalance or abnormality of the single placenta serving two twins. This unequal placental sharing can cause complications including twin-twin transfusion syndrome (TTTS), twin anemia-polycythemia sequence (TAPS), selective intrauterine growth restriction or twin reversed arterial perfusion sequence (TRAP). Monochorionicity also makes the management of these specific complications as well as that of a severe malformation in one twin hazardous since the spontaneous death of one twin exposes the co-twin to a risk of exsanguination into the dead twin and its placenta. The latter is responsible for the death of the co-twin in up to 20% of the cases and in ischemic sequelae in about the same proportions in the survivors. Although the symptoms of all these complications are very different, the keystone of their management comes down to either surgical destruction of the inter-twin anastomoses on the chorionic plate when aiming at dual survival or selective and permanent occlusion of the cord of a severely affected twin aiming at protecting the normal co-twin. This can be best achieved by fetoscopic selective laser coagulation and bipolar forceps cord coagulation respectively. PMID:20855238

Chalouhi, G E; Stirnemann, J J; Salomon, L J; Essaoui, M; Quibel, T; Ville, Y

2010-12-01

96

Cerebral metabolism, anatomy, and cognition in monozygotic twins discordant for dementia of the Alzheimer type.  

PubMed Central

One pair of monozygotic twins discordant for dementia of the Alzheimer type (DAT) was studied using neuropsychological testing, quantitative x-ray computed tomography (QCT) and magnetic resonance imaging (MRI) of the brain. Cerebral glucose metabolism was measured using positron emission tomography (PET) and 2-[18-F]fluoro-2-deoxy-D-glucose (FDG). The affected twin had a seven year history of progressive cognitive impairment and was severely demented. Neuropsychological testing of the affected twin demonstrated marked deficits in all areas of cognitive function. The asymptomatic twin showed some impairment on tests of perceptual organisation and delayed recall. The affected twin had loss of gray matter and ventricular enlargement on QCT and MRI compared with healthy controls (p less than 0.05). He also had frontal and parietal lobe hypometabolism and increased asymmetry of metabolism on PET compared to both his twin and healthy age-matched controls (p less than 0.05). PET, QCT, and MRI distinguished changes in the twin with DAT compared with his brother and healthy controls. Although the subtle neuropsychological abnormalities of the asymptomatic twin may be signs of early DAT, they were not accompanied by any changes in regional cerebral metabolism or brain structure. Images PMID:3494105

Luxenberg, J S; May, C; Haxby, J V; Grady, C; Moore, A; Berg, G; White, B J; Robinette, D; Rapoport, S I

1987-01-01

97

Chronic Idiopathic Neutrophilia in Two Twins  

PubMed Central

Neutrophilia in adults refers to an alteration in the total number of blood neutrophils that is in excess of about 7500 cells/?L. This definition is restrictive in childhood as neutrophil count is age-dependent. Chronic Idiopathic Neutrophilia (CIN) refers to a condition that persists for many years in individuals who appear otherwise healthy. CIN is rarely mentioned in scientific literature and in academic books of hematology; only few words are dedicated to this topic. We report a case study of two twins with CIN followed from the first year of life to 24 years of age. To the best of our knowledge this is the first case report of two twins with CIN followed through a long period of time. We believe that our observation may contribute to better understand and characterize this hematologic abnormality. PMID:25431700

Miniero, Roberto; Altomare, Federica; Fusaro, Carla

2014-01-01

98

Serial MR imaging and 1H-MR spectroscopy in monozygotic twins with Tay-Sachs disease.  

PubMed

Four-year-old monozygotic female twins with early onset Tay-Sachs disease are described. The sisters showed similar slowly progressive clinical symptoms and deterioration, however the younger sister also demonstrated intractable myoclonus in the right leg. The serial MR images and (1)H-MR spectroscopy of the brain were obtained in both twins. MR images showed high intensity on T (2)-weighted image in the bilateral white matter, however there were no signal changes in the basal ganglia and thalamus during any of the phases. The ratio of N-acetylaspartate (NAA)/creatine (Cr) was decreased in the both white matter lesions and the corpus striatum, and that of myoinositol (mI)/Cr was increased in the damaged white matter on MR spectroscopy. The elevation of the lactate peak was clearly demonstrated in the left basal ganglia of the younger sister; however it was not shown in cerebral lesions of the elder sister. Changes in metabolites on MR spectroscopy were closely linked to the respective clinical features of each twin. Follow-up examination by (1)H-MR spectroscopy is useful for the evaluation of neuronal changes in children with Tay-Sachs disease. PMID:19294598

Imamura, A; Miyajima, H; Ito, R; Orii, K O

2008-10-01

99

Are There Differences in Brain Morphometry Between Twins and Unrelated Singletons? A Pediatric MRI Study  

PubMed Central

Twins provide a unique capacity to explore relative genetic and environmental contributions to brain development, but results are applicable to non-twin populations only to the extent that twin and singleton brains are alike. A reason to suspect differences is that as a group twins are more likely than singletons to experience adverse prenatal and perinatal events that may affect brain development. We sought to assess whether this increased risk leads to differences in child or adolescent brain anatomy in twins who do not experience behavioral or neurological sequelae during the perinatal period. Brain MRI scans of 185 healthy pediatric twins (mean age=11.0, s.d.=3.6) were compared to scans of 167 age- and sex-matched unrelated singletons on brain structures measured, which included gray and white matter lobar volumes, ventricular volume, and area of the corpus callosum. There were no significant differences between groups for any structure, despite sufficient power for low Type II (i.e. false negative) error. The implications of these results are twofold: (1) within this age range and for these measures, it is appropriate to include healthy twins in studies of typical brain development, and (2) findings regarding heritability of brain structures obtained from twin studies can be generalized to non-twin populations. PMID:20100212

Ordaz, Sarah J.; Lenroot, Rhoshel K.; Wallace, Gregory L.; Clasen, Liv S.; Blumenthal, Jonathan D.; Schmitt, J. Eric; Giedd, Jay N.

2009-01-01

100

Stage-based treatment of twin-twin transfusion syndrome  

Microsoft Academic Search

Objective: The purpose of this study was to compare the outcomes of patients with twin-twin transfusion syndrome who were treated with either serial amniocentesis or selective laser photocoagulation of communicating vessels according to disease severity (stage). Study Design: Centers that were experienced in the treatment of twin-twin transfusion syndrome were invited to share stage-based perinatal outcome data. All patients met

Rubén A. Quintero; Jan E. Dickinson; Walter J. Morales; Patricia W. Bornick; Carlos Bermúdez; Robert Cincotta; Fung Yee Chan; Mary H. Allen

2003-01-01

101

Placental types and twin-twin transfusion syndrome  

Microsoft Academic Search

Objective: The purpose of this study was to assess the value of a proposed classification of monochorionic placenta in reference to twin-twin transfusion syndrome. Study Design: The placentas from laser-treated patients with twin-twin transfusion syndrome and from uncomplicated monochorionic pregnancies that were delivered between January 1997 and December 2000 were included in the study. Placentas were classified as type A

Carlos Bermúdez; Carlos H. Becerra; Patricia W. Bornick; Mary H. Allen; Jorge Arroyo; Rubén A. Quintero

2002-01-01

102

Refinement of Twinned Structures with SHELXL97  

Microsoft Academic Search

Four examples of the refinement of twinned structures are discussed. These structures illustrate three different types of twins: twinning by merohedry, pseudo-mero- hedry and non-merohedral twins. How the twinning was detected, how the structures were solved and how they were refined are shown in this paper. The difference between a refinement as a disordered model and a twinned model is

Regine Herbst-Irmer; George M. Sheldrick

1998-01-01

103

Healthy Aging  

MedlinePLUS

Healthy Aging This category offers tips on how to stay healthy, get good health care, and manage lifestyle changes ... Problems with Smell Problems with Taste Sleep and Aging Taking Medicines Talking with Your Doctor These Age ...

104

Splitting the Chromosome: Cutting the Ties That Bind Sister Chromatids  

Microsoft Academic Search

In eukaryotic cells, sister DNA molecules remain physically connected from their production at S phase until their separation during anaphase. This cohesion is essential for the separation of sister chromatids to opposite poles of the cell at mitosis. It also permits chromosome segregation to take place long after duplication has been completed. Recent work has identified a multisubunit complex called

Kim Nasmyth; Jan-Michael Peters; Frank Uhlmann

2000-01-01

105

Fused sister kinetochores initiate the reductional division in meiosis I  

E-print Network

LETTERS Fused sister kinetochores initiate the reductional division in meiosis I Xuexian Li1 and R. Kelly Dawe1,2,3 During meiosis I the genome is reduced to the haploid content by a coordinated MIS12­NDC80 bridge between sister kinetochores at meiosis I is broken. Kinetochores separate

106

Salicylate Metabolism in Twins  

PubMed Central

To evaluate the contribution of genetic influences on the individual variation in plateau serum salicylate levels, salicylate metabolism was studied in seven pairs of identical and six pairs of fraternal twins. Under the conditions of this study, after a single i.v. dose (40 mg/kg) of sodium salicylate, the serum salicylate concentration versus time curve approximated a straight line on linear coordinates (appeared approximately zero order). The slopes of the decay curves ranged between 0.64 and 1.02. The intrapair variation for identical twin pairs was significantly less than for fraternal twin pairs (P = 0.044). Likewise pleateau serum salicylic acid concentrations (milligrams/deciliter) and total salicylic acid excretion rate after multiple doses demonstrated significantly less intrapair variation for identical twins than for fraternal twins (P = 0.043 and 0.006). Plateau salicylurate excretion (milligram/kilogram per hour) differences after multiple dosing had a P = 0.067. Michaelis-Menton constant for salicylurate formation and hours to 50% excretion after the i.v. dose were not different when comparing identical and nonidentical twins. Salicylurate formation rates were increased after 3 days of oral therapy, and this induction phenomenon may account for much of the apparent discrepancy between genetic influences on salicylurate formation rates observed after single and multiple dose salicylate administration. This study suggests that the plateau concentration of serum salicylate varies among individuals given the same weight-adjusted dose in part because of genetically determined variations in their metabolism of salicylate. PMID:559691

Furst, Daniel E.; Gupta, Niroo; Paulus, Harold E.

1977-01-01

107

77 FR 13585 - Three Sisters Irrigation District; Notice of Application Accepted for Filing and Soliciting...  

Federal Register 2010, 2011, 2012, 2013

...Project No. 14364-000] Three Sisters Irrigation District; Notice of Application Accepted...2012. d. Applicant: Three Sisters Irrigation District. e. Name of Project: Three Sisters Irrigation District Hydroelectric Project....

2012-03-07

108

Chimerism of buccal membrane cells in a monochorionic dizygotic twin.  

PubMed

No monochorionic dizygotic twins (MCDZTs) with cellular chimerism involving cells other than blood cells have been reported in the literature to date. Here we report a probable first case of MCDZTs with buccal cell chimerism. A 32-year-old woman conceived twins by in vitro fertilization by using 2 cryopreserved blastocysts that were transferred into her uterus. An ultrasound scan at 8 weeks' gestation showed signs indicative of monochorionic twins. A healthy boy and a healthy girl were born, showing no sexual ambiguity. Cytogenetic analyses and microsatellite studies demonstrated chimerism in blood cells of both twins. Notably, repeated fluorescence in situ hybridization and microsatellite studies revealed chimerism in buccal cells obtained from 1 of the twins. Although the mechanism through which buccal cell chimerism was generated remains to be elucidated, ectopic differentiation of chimeric hematopoietic cells that migrated to the buccal membrane or the cellular transfer between the 2 embryos at the early stage of development might be responsible for the phenomenon. This hypothesis raises an interesting issue regarding embryonic development and cellular differentiation into organs during fetal development. Given the possibility of cryptic chimerism in various organs including gonadal tissues in MCDZTs, close observation will be required to determine whether complications develop in the course of the patients' growth. PMID:24685957

Fumoto, Seiko; Hosoi, Kenichiro; Ohnishi, Hiroaki; Hoshina, Hiroaki; Yan, Kunimasa; Saji, Hiroh; Oka, Akira

2014-04-01

109

Twin Supergravities Diederik Roest 1  

E-print Network

UG-09-04 Twin Supergravities Diederik Roest 1 and Henning Samtleben 2 1 Centre for Theoretical of supergravities can have identical bosonic field content but different fermionic extensions. Such twin theories discuss the possible gaugings and scalar poten- tials of twin theories. This allows to pinpoint to which

Paris-Sud XI, Université de

110

The Composite Twin Higgs scenario  

E-print Network

Based on an explicit model, we propose and discuss the generic features of a possible implementation of the Twin Higgs program in the context of composite Higgs models. We find that the Twin Higgs quadratic divergence cancellation argument can be uplifted to a genuine protection of the Higgs potential, based on symmetries and selection rules, but only under certain conditions which are not fulfilled in some of the existing models. We also find that a viable scenario, not plagued by a massless Twin Photon, can be obtained by not gauging the Twin Hypercharge and taking this as the only source of Twin Symmetry breaking at a very high scale.

Barbieri, Riccardo; Rattazzi, Riccardo; Wulzer, Andrea

2015-01-01

111

The Composite Twin Higgs scenario  

E-print Network

Based on an explicit model, we propose and discuss the generic features of a possible implementation of the Twin Higgs program in the context of composite Higgs models. We find that the Twin Higgs quadratic divergence cancellation argument can be uplifted to a genuine protection of the Higgs potential, based on symmetries and selection rules, but only under certain conditions which are not fulfilled in some of the existing models. We also find that a viable scenario, not plagued by a massless Twin Photon, can be obtained by not gauging the Twin Hypercharge and taking this as the only source of Twin Symmetry breaking at a very high scale.

Riccardo Barbieri; Davide Greco; Riccardo Rattazzi; Andrea Wulzer

2015-01-30

112

Twin Paradox and Causality  

E-print Network

After pointing out the historical avatar at the origin of a would be twin or clock paradox, we argue that, at least on a local scale, the (re-qualified) paradox is but a necessary consequence of the sole principle of causality.

T. Grandou; J. L. Rubin

2007-04-20

113

Identical Twins Raised Apart  

ERIC Educational Resources Information Center

This article describes a bivariate data set that is interesting to students. Indeed, this particular data set, which involves twins and IQ, has sparked more student interest than any other set that I have presented. Specific uses of the data set are presented.

Farnsworth, David L.

2015-01-01

114

Healthy Diet  

NSDL National Science Digital Library

This project will explain the importance of a balanced diet as well as learn nutrition facts to help them apply a healthy diet in their everyday lives Eating good foods is very important to living a healthy life. Click on 'food groups' pyramid below and learn about what types of food should be in your daily diet. Food groups 1. What makes a certain food healthy? 2. Do you eat the foods from the pyramid on a regular ...

Mrs. Parker

2009-09-28

115

Creating Sister Cities: An Exchange Across Hemispheres  

NASA Astrophysics Data System (ADS)

Sponsored by Associated Universities, Inc. (AUI) and the National Radio Astronomy Observatory (NRAO), this project creates a cultural and educational exchange program between communities in South and North America, linking San Pedro de Atacama in Chile and Magdalena, New Mexico in the United States. Both communities have similar demographics, are in relatively undeveloped regions of high-elevation desert, and are located near major international radio astronomy research facilities. The Atacama Large Millimeter/submillimeter Array (ALMA) is just 40 km east of San Pedro; the Very Large Array (VLA) is just 40 km west of Magdalena. In February 2007, the Mayor of San Pedro and two teachers visited Magdalena for two weeks; in July 2007 three teachers from Magdalena will visit San Pedro. These visits enable the communities to lay the foundation for a permanent, unique partnership. The teachers are sharing expertise and teaching methodologies for physics and astronomy. In addition to creating science education opportunities, this project offers students linguistic and cultural connections. The town of San Pedro, Chile, hosts nearly 100,000 tourists per year, and English language skills are highly valued by local students. Through exchanges enabled by email and distance conferencing, San Pedro and Magdalena students will improve English and Spanish language skills while teaching each other about science and their respective cultures. This poster describes the AUI/NRAO Sister Cities program, including the challenges of cross-cultural communication and the rewards of interpersonal exchanges between continents and cultures.

Adams, M. T.; Cabezon, S. A.; Hardy, E.; Harrison, R. J.

2008-06-01

116

Twinning-like lattice reorientation without a crystallographic twinning plane  

NASA Astrophysics Data System (ADS)

Twinning on the plane is a common mode of plastic deformation for hexagonal-close-packed metals. Here we report, by monitoring the deformation of submicron-sized single-crystal magnesium compressed normal to its prismatic plane with transmission electron microscopy, the reorientation of the parent lattice to a ‘twin’ lattice, producing an orientational relationship akin to that of the conventional twinning, but without a crystallographic mirror plane, and giving plastic strain that is not simple shear. Aberration-corrected transmission electron microscopy observations reveal that the boundary between the parent lattice and the ‘twin’ lattice is composed predominantly of semicoherent basal/prismatic interfaces instead of the twinning plane. The migration of this boundary is dominated by the movement of these interfaces undergoing basal/prismatic transformation via local rearrangements of atoms. This newly discovered deformation mode by boundary motion mimics conventional deformation twinning but is distinct from the latter and, as such, broadens the known mechanisms of plasticity.

Liu, Bo-Yu; Wang, Jian; Li, Bin; Lu, Lu; Zhang, Xi-Yan; Shan, Zhi-Wei; Li, Ju; Jia, Chun-Lin; Sun, Jun; Ma, Evan

2014-02-01

117

Angioarchitecture of monochorionic placentas in relation to the twin-twin transfusion syndrome  

Microsoft Academic Search

OBJECTIVE: Twin-twin transfusion syndrome in the midtrimester is associated with a perinatal mortality rate exceeding 80%. Although attributed to intertwin transfusion along vascular anastomoses, these occur in all monochorial placentas, not just the 10% with twin-twin transfusion syndrome. We compared fetoplacental angioarchitecture in monochorionic twin placentas with and without twin-twin transfusion syndrome.STUDY DESIGN: The fetoplacental circulations of both twins in

Rekha Bajoria; Jonathan Wigglesworth; Nicholas M. Fisk

1995-01-01

118

Linking Chromosome Duplication and Segregation via Sister Chromatid Cohesion  

PubMed Central

DNA replication during S phase generates two identical copies of each chromosome. Each chromosome is destined for a daughter cell, but each daughter must receive one and only one copy of each chromosome. To ensure accurate chromosome segregation, eukaryotic cells are equipped with a mechanism to pair the chromosomes during chromosome duplication and hold the pairs until a bi-oriented mitotic spindle is formed and the pairs are pulled apart. This mechanism is known as sister chromatid cohesion, and its actions span the entire cell cycle. During G1, before DNA is copied during S phase, proteins termed cohesins are loaded onto DNA. Paired chromosomes are held together through G2 phase, and finally the cohesins are dismantled during mitosis. The processes governing sister chromatid cohesion ensure that newly replicated sisters are held together from the moment they are generated to the metaphase–anaphase transition, when sisters separate. PMID:24906310

Leman, Adam R.; Noguchi, Eishi

2014-01-01

119

38. 8 sisters and powerhouse, pulverizer building for powerhouse, coal ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

38. 8 sisters and powerhouse, pulverizer building for powerhouse, coal conveyor, blast stoves, "A" furnace, stoves, "B" furnace, stoves, "C" furnace, bottle cars. Looking south - Rouge Steel Company, 3001 Miller Road, Dearborn, Wayne County, MI

120

Mechanisms for differences in monozygous twins  

Microsoft Academic Search

Monozygous (MZ) twins are often described as being physically and genetically identical. Clinical determination of zygosity relies on the assumption that any physical differences between a pair of twins imply they are dizygous. Most twin research relies on the assumption that dizygous twins share approximately 50% of the same genes, whereas monozygous twins share 100%. There is, however, increasing evidence

Paul Gringras; Wai Chen

2001-01-01

121

Healthy Living  

MedlinePLUS

... a healthy weight Eat a variety of healthy foods, and limit calories and saturated fat Be physically active Control your blood pressure and cholesterol Don't smoke Protect yourself from too much sun Drink alcohol in moderation, or don't drink at all Agency for Healthcare Research and Quality

122

A Quantum Twin Paradox  

E-print Network

The Classical Twin Paradox is widely dealt in literature and neatly resolved. In addition, it is also well known that, when looking at two systems which are boosted relative to each other, the concept of the simultaneous effect of a quantum measurement in space-time causes some discrepancies in the cause-effect behavior. However, these discrepancies have been thought not to cause any apparent paradox except for violating the Free-Will postulate. In this paper we suggest that using the local t axis, all over space, as the axis in which the quantum measurement is thought to be simultaneous, we do reach a kind of true "Twin Paradox". The resolution of this paradox requires the introduction of a global proper time into a covariant quantum theory.

Doron ludwin

2011-02-09

123

Healthy Lifestyle  

NSDL National Science Digital Library

The Mayo Clinic has a terrific public outreach program, and this website provides a rich array of materials that deal with common and uncommon medical conditions. The Healthy Lifestyle area contains a range of tools and information for a healthy lifestyle. The sections include Healthy Lifestyle Topics, Life Stages, and Healthy Recipes. Within each section, visitors will find multimedia clips, expert answers, additional resources, and links to commonly asked questions. The Weight Loss area is particularly useful, as it contains over 25 different resources designed to help individuals address this increasingly common desire in a way that is balanced and meaningful. On a related note, the Healthy Recipes are a nice complement to these materials as they include suggestions for drinks, entrees, and side dishes.

2012-08-10

124

Tribute to dr louis keith: twin and physician extraordinaire/twin research reports: influences on asthma severity; chimerism revisited; DNA strand break repair/media reports: twins born apart; elevated twin frequencies; celebrity father of twins; conjoined twinning.  

PubMed

The International Society for Twin Studies has lost a valued friend and colleague. Dr Louis Keith, Emeritus Professor of Obstetrics and Gynecology at Northwestern University, in Chicago, passed away on Sunday, July 6, 2014. His life and work with twins will be acknowledged at the November 2014 International Twin Congress in Budapest, Hungary. Next, twin research reports on the severity of asthma symptoms, a case of chimerism, and factors affecting DNA breakage and repair mechanisms are reviewed. Media reports cover twins born apart, elevated twin frequencies, a celebrity father of twins, and a family's decision to keep conjoined twins together. PMID:25213730

Segal, Nancy L

2014-10-01

125

Twin Cities Metro Advanced Practice Center  

E-print Network

Twin Cities Metro Advanced Practice Center In An Emergency: Equipment & Supplies List for Food Vietnamese.................................12 #12;Twin Cities Metro Advanced Practice Center Funded Offsite cold storage options (contact info for truck, warehouse) #12;Twin Cities Metro Advanced Practice

126

Sister chromatid exchange induced by short-lived monoadducts produced by the bifunctional agents mitomycin C and 8-methoxypsoralen. [CHO cells  

SciTech Connect

To see if DNA crosslinks are involved in the induction of sister chromated exchange (SCE), Chinese hamster ovary cells were exposed to two bifunctional alkylating agents,mitomycin C and 8-methoxypsoralen, and their monofunctional derivatives, decarbamoyl mitomycin C and angelicin. The data indicates that monoadducts, rather than crosslinks, are responsible for SCE formation. Furthermore, all agents but angelicin produced short-lived lesions that led to SCEs in the first period of DNA replication after treatment (twin SCEs). In contrast, angelicin, like methyl methanesulfonate and N-acetoxyacetylaminofluorene, produced lesions that lasted more than one cycle, indicating that several different types of DNA lesions are capable of SCE induction.

Linnainmaa, K.; Wolff, S.

1982-01-01

127

Healthy Sexuality  

MedlinePLUS Videos and Cool Tools

... a sexual experience is safe, healthy, and enjoyable. Sexual health is a vital part of a person’s total well-being. Of course, sex is essential for reproduction, but it can also build intimacy in relationships ...

128

Healthy Eyes  

MedlinePLUS

... los Ojos Cómo hablarle a su oculista Healthy Eyes Listen Having a comprehensive dilated eye exam is ... or contact lenses. What is a comprehensive dilated eye exam? A comprehensive dilated eye exam is a ...

129

Healthy Eyes  

MedlinePLUS

... of this page please turn Javascript on. Healthy Eyes Maintaining Your Vision Click for more information Taking ... have a comprehensive dilated eye exam. Who Performs Eye Exams? An eye care professional is either an ...

130

Occurrence of Different External Ear Deformities in Monozygotic Twins: Report of 2 Cases  

PubMed Central

Summary: Microtia is a spectrum of congenital deformities, which varies from barely discernable to anotia. Twinning is a well-known risk factor for congenital defects including external ear deformities. Monozygotic twins usually show identical appearances as well as congenital malformations. In special conditions as ear deformities, “mirror-image” may also occur. We report 2 cases of monozygotic twins with different ear deformities. The 8-year-old propositus with lobule type microtia and her identical female twin presented with facial symmetry. Patient A had sausage-type right microtia with absence of external auditory canal. The left external ear showed normal appearance. Patient B presented with left-sided preauricular skin tag and right-sided malformation of tragus with skin tag combined with hyperplasia of underlying cartilage. A granule-size skin tag was also noticed at crus of right helix. A 7-year-old male patient with right-sided conchal type microtia presented to an ear reconstruction center. The patient’s mother showed normal auricular appearance. Her monozygotic twin sister, whose son and daughter had normal ear appearance, was diagnosed with a leftsided lobule type microtia. PMID:25426389

Hu, Jin-Tian; Liu, Tun; Qian, Jin; Zhang, Yong-Biao; Zhou, Xu

2014-01-01

131

Neonatal morbidity in twin-twin transfusion syndrome.  

PubMed

Twin-twin transfusion syndrome (TTTS) is a severe complication of monochorionic twin pregnancies associated with high perinatal mortality and morbidity rates. Management in TTTS is a major challenge for obstetricians and neonatologists. Twins which are often born prematurely and may suffer from typical conditions associated with prematurity. In addition, surviving twins with TTTS are at increased risk for other complications including neurological, cardiovascular, renal and hematologic morbidity. Rare complications such as hypoxic-ischemic lesions to limbs or intestines and amniotic band syndrome have also been reported in TTTS survivors. This review focuses on the neonatal and pediatric mortality and morbidity in TTTS survivors, with special emphasis on the long-term neurodevelopmental outcome. PMID:21784588

Lopriore, Enrico; Oepkes, Dick; Walther, Frans J

2011-09-01

132

Transformation: From Twin to Individual  

ERIC Educational Resources Information Center

This article explores some of the complexities of psychotherapy with an identical twin. The difficulty of developing in psychotherapy while so much of what is oneself is located in the other twin will also be explored. The use of the countertransference as a therapeutic method will be considered as the young person develops her unique, separate…

Magagna, Jeanne

2007-01-01

133

Labor patterns in twin gestations  

PubMed Central

Objective To compare labor progression in twin vs singleton gestations. Study Design Retrospective review of electronic database created by Consortium on Safe Labor, reflecting labor and delivery information from 12 clinical centers 2002-2008. Women with twin gestations, cephalic presentation of presenting twin, gestational age ?34 weeks, with ?2 cervical examinations were included. Exclusion criteria were fetal anomalies or demise. Singleton controls were selected by the same criteria. Categorical variables were analyzed by ?2; continuous by Student t test. Interval censored regression was used to determine distribution for time of cervical dilation in centimeters, or “traverse times,” and controlled for confounding factors. Repeated-measures analysis constructed mean labor curves by parity and number of fetuses. Results A total of 891 twin gestations were compared with 100,513 singleton controls. Twin gestations were more often older, white or African American, earlier gestational age, increased prepregnancy body mass index, and with lower birthweight. There was no difference in number of prior cesarean deliveries, induction, or augmentation, or epidural use. Median traverse times increased at every centimeter interval in nulliparous twins, in both unadjusted and adjusted analysis (P < .01). A similar pattern was noted for multiparas in both analyses. Labor curves demonstrated a delayed inflection point in the labor pattern for nulliparous and multiparous twin gestations. Conclusion Both nulliparous and multiparous women have slower progression of active phase labor with twins even when controlling for confounding factors. PMID:23871795

Leftwich, Heidi K.; Zaki, Mary N.; Wilkins, Isabelle; Hibbard, Judith U.

2014-01-01

134

Mapping Genetic Influences on Brain Activation during the N-Back Working Memory Task: An fMRI Study of 315 Twins  

E-print Network

of 315 Twins Gabriëlla A.M. Blokland1,2,3 , Katie L. McMahon2 , Paul M. Thompson4 , Greig I. de ZubicarayImaging, UCLA School of Medicine, Los Angeles, CA, United States Introduction: Twin studies can disentangle, using functional MRI (fMRI) during a working memory task in healthy twin pairs. Methods: BOLD fMRI data

Thompson, Paul

135

Twin Language Development: A Case Study of a Twin with a Cochlear Implant and a Twin with Typical Hearing  

ERIC Educational Resources Information Center

This study was a longitudinal examination (21 month follow-up) of language development in a pair of fraternal twins. One twin received a cochlear implant at age 20 months secondary to sensorineural hearing loss. The other twin had normal hearing. Data were obtained every 6 months following her initial cochlear implant stimulation. Both twins

Seung, HyeKyeung; Holmes, Alice; Colburn, Michelle

2005-01-01

136

Healthy Eating  

NSDL National Science Digital Library

This Project will help you to discover how you're eating, and how that affects your life. You will also use the tools provided to help make healthy eating choices. First, Calculate your Body Mass Index using the BMI Calculator. Then, after exploring the website, answer these questions: 1) What exactly is the BMI? 2) What are two limitations of the BMI Calculator? 3) What is a healthy BMI for YOU (age group height? 4) List 7 other risk factors that can contribute to heart ...

BRobison

2010-12-03

137

The Essene's sister sect in Egypt: another medical site?  

PubMed

The Essenes were, allegedly, the authors of the Dead Sea Scrolls and were settled by the Dead Sea. An ancient source locates their sister sect, The 'Therapeutae', as being by the shores of Lake Mareotis in Egypt. No scholar has previously sought to locate where exactly on Lake Mareotis they were settled. Using clues from Essene sites around the Dead Sea, an attempt is made to suggest a specific location for the Therapeutae. Since there are signs of medical activity at many of the Essene sites, a site with medical association is also sought for the location of the Essene's sister sect in Egypt. A suitable site is found at Canopus. PMID:12557736

Moss, G A

2002-12-01

138

Catholic Sister Nurses in Selma, Alabama, 1940–1972  

PubMed Central

This study analyzes the activities of religious sister nurses as they confronted racism in the American South from 1940 to 1972. Selma was chosen as a case study because, in the 1960s, events in that southern town marked a turning point in the civil rights movement in the United States. This is a story about the workings of gender, race, religion, and nursing. The sisters’ work demonstrates how an analysis of race in nursing history is incomplete without an understanding of the roles that a number of Catholic religious women took in reaching out to African Americans in the Deep South. PMID:19218843

Wall, Barbra Mann

2009-01-01

139

Male twins reduce fitness of female co-twins Virpi Lummaa*  

E-print Network

Male twins reduce fitness of female co-twins in humans Virpi Lummaa* , Jenni E. Pettay , and Andrew with a male co-twin for daughter lifetime reproductive success, and the fitness conse- quences for mothers of producing mixed-sex twins in preindustrial (1734­1888) Finns. We show that daughters born with a male co-twin

Lummaa, Virpi

140

Twins Vertices in Hypergraphs Raoul Medina1  

E-print Network

Twins Vertices in Hypergraphs Raoul Medina1 and Caroline Noyer and Olivier Raynaud2 Research Report;Abstract Twin vertices in graphs correspond to vertices sharing the same neighbor- hood. We propose an extension to hypergraphs of the concept of twin ver- tices. For this we give two characterizations of twin

Boyer, Edmond

141

Twin Estimates for Slopes Humberto Munoz  

E-print Network

Twin Estimates for Slopes by Humberto Muâ?ťnoz R. Baker Kearfott, rbk@louisiana.edu Department author's Ph.D. dissertation Interval Slopes and Twin Slope Arithmetic in Nonsmooth Optimization, University of Louisiana at Lafayette, 2001. Twin Estimates for Slopes May 25, VC02--1 #12; What is Twin

Kearfott, R. Baker

142

Best Practices for Twin Placement in School  

ERIC Educational Resources Information Center

The children's book "Two Is for Twins" celebrates twins and illustrates the many "twos" in a child's world. The uniqueness of twos does not have to mean separate classrooms for twins in child development programs, preschool, or elementary school settings. With recent dramatic increases in the US twin population, how should educators address the…

Lacina, Jan

2012-01-01

143

Epilepsy and electrophysiological findings in polish twins with glycogenosis type IIIb.  

PubMed

Glycogen storage diseases are rare genetic disorders, mostly autosomal recessively inherited. Abnormal accumulation is because of the lack of one of the enzymes involved in glycogen metabolism. Neurological manifestation of the diseases involves muscle weakness and hypoglycemia-induced seizures. In this article, we present a history of twin sisters with unusual coincidence of glycogenosis type IIIb and epilepsy. Hypoglycemic background of seizures and organic changes of the central nervous system were excluded. Since the introduction of antiepileptic treatment, the patients have been seizure-free; however, paroxysmal electroencephalographic (EEG) changes have persisted. A high-protein and low-carbohydrate diet has protected them against hypoglycemia. PMID:24357677

Kroczka, S?awomir; Biedro?, Agnieszka; Kaci?ski, Marek

2014-07-01

144

Heterogeneity of responses to orthostatic stress in homozygous twins.  

PubMed

Early analysis into the role of genetics on cardiovascular regulation has been accomplished by comparing blood pressure and heart rate in homozygous twins during unstressed, resting physiological conditions. However, many variables, including cognitive and environmental factors, contribute to the regulation of cardiovascular hemodynamics. Therefore, the purpose of this study was to determine the hemodynamic response of identical twins to an orthostatic stress, ranging from supine rest to presyncope. Heart rate, arterial blood pressure, middle cerebral artery blood velocity, an index of cerebrovascular resistance, cardiac output, total peripheral resistance, and end-tidal carbon dioxide were measured in 16 healthy monozygotic twin pairs. Five minutes of supine resting baseline data were collected, followed by 5 min of 60 degrees head-up tilt. After 5 min of head-up tilt, lower body negative pressure was applied in increments of 10 mmHg every 3 min until the onset of presyncope, at which time the subject was returned to the supine position for a 5-min recovery period. The data indicate that cardiovascular regulation under orthostatic stress demonstrates a significant degree of variance between identical twins, despite similar orthostatic tolerance. As the level of stress increases, so does the difference in the cardiovascular response within a twin pair. The elevated variance with increasing stress may be due to an increase in the role of environmental factors, as the influential role of genetics nears a functional limit. Therefore, although orthostatic tolerance times were very similar between identical twins, the mechanism involved in sustaining cardiovascular function during increasing stress was different. PMID:17008441

O'Leary, D D; Hughson, R L; Shoemaker, J K; Greaves, D K; Watenpaugh, D E; Macias, B R; Hargens, A R

2007-01-01

145

Healthy Learning.  

ERIC Educational Resources Information Center

Offers ten suggestions for schools and universities to help maintain a healthy indoor environment: proper flooring, sanitary washrooms, consistent maintenance, indoor air quality, preventing mold, daylighting, good acoustics, avoiding volatile organic compounds (VOCs), ergonomic furniture, and well-maintained roofs. (EV)

Kennedy, Mike

2003-01-01

146

Healthy Eating  

MedlinePLUS

... little later to accommodate a teen who's at sports practice. It also can mean setting aside time on the weekends when it may be more convenient to gather as a group, such as for Sunday brunch. Continue Stock Up on Healthy Foods Kids, especially younger ones, ...

147

184. Photocopy of drawing (taken from right corner of Twin ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

184. Photocopy of drawing (taken from right corner of Twin Falls Canal Company drawing #7017, located in Twin Falls Canal Company office, Twin Falls, Idaho). ORIGINAL 1900 SEGREGATION DAM PLAN, TWIN FALLS COUNTY, MILNER, IDAHO. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

148

Failure of vincristine induce twinning  

NASA Technical Reports Server (NTRS)

Mammalian ova do not contain axes of symmetry from which are derived embryonic axes of symmetry. Mammalian axis determination is an early embryologic event occurring at about the time that monozygous twinning in mice. (Kaufma MH & O'Shea KS, 1978, Nature 276:707) and an attempt was made to reproduce their work in several strains of mice. Over 3200 embryos were examined without any twins being found. To rule out the possibility that vincristine caused twinning plus some lethal malformation (with subsequent resorption of the embryo) the embryos were examined 36-60 hours after vincristine treatment.

Binder, M.

1984-01-01

149

Monozygotic Twins Exhibit Numerous Epigenetic Differences: Clues to Twin Discordance?  

Microsoft Academic Search

The goal of this pilot study was to explore the putative molecular mechanisms underlying the phenotypic discordance of monozygotic (MZ) twins. Thus, patterns of epigenetic DNA modification were investigated in the 5?-regulatory region of the dopamine D2 receptor gene (DRD2) in two pairs of monozygotic twins, one concordant and one discordant for schizophrenia. The bisulfite DNA modification-based approach was used

Arturas Petronis; Irving I. Gottesman; Peixiang Kan; James L. Kennedy; Vincenzo S. Basile; Andrew D. Paterson; Violeta Popendikyte

2003-01-01

150

Monozygotic Twins Exhibit Numerous Epigenetic Differences: Clues to Twin Discordance?  

Microsoft Academic Search

The goal of this pilot study was to explore the putative molecular mechanisms underlying the phenotypic dis- cordance of monozygotic (MZ) twins. Thus, patterns of epigenetic DNA modification were investigated in the 5-regulatory region of the dopamine D2 receptor gene (DRD2) in two pairs of monozygotic twins, one concordant and one discordant for schizophrenia. The bisulfite DNA modification-based approach was

Arturas Petronis; Irving I. Qottesman; Peixiang Kan; James L. Kennedy; Vincenzo S. Basile; Andrew D. Paterson; Violeta Popendikyte

151

Genome-Wide Analysis of DNA Methylation, Copy Number Variation, and Gene Expression in Monozygotic Twins Discordant for Primary Biliary Cirrhosis  

PubMed Central

Primary biliary cirrhosis (PBC) is an uncommon autoimmune disease with a homogeneous clinical phenotype that reflects incomplete disease concordance in monozygotic (MZ) twins. We have taken advantage of a unique collection consisting of genomic DNA and mRNA from peripheral blood cells of female MZ twins (n?=?3 sets) and sisters of similar age (n?=?8 pairs) discordant for disease. We performed a genome-wide study to investigate differences in (i) DNA methylation (using a custom tiled four-plex array containing tiled 50-mers 19,084 randomly chosen methylation sites), (ii) copy number variation (CNV) (with a chip including markers derived from the 1000 Genomes Project, all three HapMap phases, and recently published studies), and/or (iii) gene expression (by whole-genome expression arrays). Based on the results obtained from these three approaches we utilized quantitative PCR to compare the expression of candidate genes. Importantly, our data support consistent differences in discordant twins and siblings for the (i) methylation profiles of 60 gene regions, (ii) CNV of 10 genes, and (iii) the expression of 2 interferon-dependent genes. Quantitative PCR analysis showed that 17 of these genes are differentially expressed in discordant sibling pairs. In conclusion, we report that MZ twins and sisters discordant for PBC manifest particular epigenetic differences and highlight the value of the epigenetic study of twins. PMID:24734033

Selmi, Carlo; Cavaciocchi, Francesca; Lleo, Ana; Cheroni, Cristina; De Francesco, Raffaele; Lombardi, Simone A.; De Santis, Maria; Meda, Francesca; Raimondo, Maria Gabriella; Crotti, Chiara; Folci, Marco; Zammataro, Luca; Mayo, Marlyn J.; Bach, Nancy; Shimoda, Shinji; Gordon, Stuart C.; Miozzo, Monica; Invernizzi, Pietro; Podda, Mauro; Scavelli, Rossana; Martin, Michelle R.; Seldin, Michael F.; LaSalle, Janine M.; Gershwin, M. Eric

2014-01-01

152

Genome-wide analysis of DNA methylation, copy number variation, and gene expression in monozygotic twins discordant for primary biliary cirrhosis.  

PubMed

Primary biliary cirrhosis (PBC) is an uncommon autoimmune disease with a homogeneous clinical phenotype that reflects incomplete disease concordance in monozygotic (MZ) twins. We have taken advantage of a unique collection consisting of genomic DNA and mRNA from peripheral blood cells of female MZ twins (n?=?3 sets) and sisters of similar age (n?=?8 pairs) discordant for disease. We performed a genome-wide study to investigate differences in (i) DNA methylation (using a custom tiled four-plex array containing tiled 50-mers 19,084 randomly chosen methylation sites), (ii) copy number variation (CNV) (with a chip including markers derived from the 1000 Genomes Project, all three HapMap phases, and recently published studies), and/or (iii) gene expression (by whole-genome expression arrays). Based on the results obtained from these three approaches we utilized quantitative PCR to compare the expression of candidate genes. Importantly, our data support consistent differences in discordant twins and siblings for the (i) methylation profiles of 60 gene regions, (ii) CNV of 10 genes, and (iii) the expression of 2 interferon-dependent genes. Quantitative PCR analysis showed that 17 of these genes are differentially expressed in discordant sibling pairs. In conclusion, we report that MZ twins and sisters discordant for PBC manifest particular epigenetic differences and highlight the value of the epigenetic study of twins. PMID:24734033

Selmi, Carlo; Cavaciocchi, Francesca; Lleo, Ana; Cheroni, Cristina; De Francesco, Raffaele; Lombardi, Simone A; De Santis, Maria; Meda, Francesca; Raimondo, Maria Gabriella; Crotti, Chiara; Folci, Marco; Zammataro, Luca; Mayo, Marlyn J; Bach, Nancy; Shimoda, Shinji; Gordon, Stuart C; Miozzo, Monica; Invernizzi, Pietro; Podda, Mauro; Scavelli, Rossana; Martin, Michelle R; Seldin, Michael F; Lasalle, Janine M; Gershwin, M Eric

2014-01-01

153

Chromosome condensation and sister chromatid pairing in budding yeast  

Microsoft Academic Search

We have developed a fluorescent in situ hy- bridization (FISH) method to examine the structure of both natural chromosomes and small artificial chromo- somes during the mitotic cycle of budding yeast. Our results suggest that the pairing of sister chromatids: (a) occurs near the centromere and at multiple places along the chromosome arm as has been observed in other eukaryotic

Vincent Guacci; Eileen Hogan; Douglas Koshland

1994-01-01

154

Precocious Sister Chromatid Separation (PSCS) in Cornelia de Lange Syndrome  

PubMed Central

The Cornelia de Lange syndrome (CdLS) (OMIM# 122470) is a dominantly inherited multisystem developmental disorder. The phenotype consists of characteristic facial features, hirsutism, abnormalities of the upper extremities ranging from subtle changes in the phalanges and metacarpal bones to oligodactyly and phocomelia, gastroesophageal dysfunction, growth retardation, and neurodevelopmental delay. Prevalence is estimated to be as high as 1 in 10,000. Recently, mutations in NIPBL were identified in sporadic and familial CdLS cases. To date, mutations in this gene have been identified in over 45% of individuals with CdLS. NIPBL is the human homolog of the Drosophila Nipped-B gene. Although its function in mammalian systems has not yet been elucidated, sequence homologs of Nipped-B in yeast (Scc2 and Mis4) are required for sister chromatid cohesion during mitosis, and a similar role was recently demonstrated for Nipped-B in Drosophila. In order to evaluate NIPBL role in sister chromatid cohesion in humans, metaphase spreads on 90 probands (40 NIPBL mutation positive and 50 NIPBL mutation negative) with CdLS were evaluated for evidence of precocious sister chromatid separation (PSCS). We screened 50 metaphases from each proband and found evidence of PSCS in 41% (compared to 9% in control samples). These studies indicate that NIPBL may play a role in sister chromatid cohesion in humans as has been reported for its homologs in Drosophila and yeast. PMID:16100726

Kaur, Maninder; DeScipio, Cheryl; McCallum, Jennifer; Yaeger, Dinah; Devoto, Marcella; Jackson, Laird G.; Spinner, Nancy B.; Krantz, Ian D.

2009-01-01

155

Misorientation and reduced stretching of aligned sister kinetochores promote chromosome  

E-print Network

, are unusual in affecting the movement and orientation of paired sister chromatids at the metaphase plate of MTs that are guided toward the poles, so as to form stable bipolar attach- ments to the mitotic spindle (Kapoor, 2004). Following the completion of bipolar attachment by all chromatid pairs

Draviam, Viji M.

156

Sister M. Madeleva Wolff, C.S.C.  

ERIC Educational Resources Information Center

Sister M. Madeleva Wolff, C.S.C., teacher, essayist, poet, and college administrator, through her creative ability and innovative practices made possible major contributions to Catholic education in her lifetime. Without her strong personality and boundless energy, many of her dreams for an ideal college curriculum would not have come to fruition.…

Petit, M. Loretta

2006-01-01

157

Letters from a suicide: Van Gogh and his sister.  

PubMed

An analysis of trends over a 3-yr. period in the letters of Vincent Van Gogh to his sister as the time of his suicide approached identified 8 trends, including an increase in words concerned with anxiety and words concerned with the past. PMID:20524537

Lester, David

2010-04-01

158

Sibling Relationships in Classical Athens: Brother-Sister Ties  

Microsoft Academic Search

This article examines the private orations of classical Athens for evidence of the relations between brothers, brothers and sisters, and brothers-in-law. Although affection could exist between male siblings, Athenian inheritance laws, requiring equal division of the paternal estate among male heirs, stimulated conflict between brothers. Females, however, could not inherit if they had brothers, neither were their dowries equal to

Cheryl Anne Cox

1988-01-01

159

Incomplete sister chromatid separation of long chromosome arms  

Microsoft Academic Search

Chromosome segregation ensures the equal partitioning of chromosomes at mitosis. However, long chromosome arms may pose a problem for complete sister chromatid separation. In this paper we report on the analysis of cell division in primary cells from field vole Microtus agrestis, a species with 52 chromosomes including two giant sex chromosomes. Dual chromosome painting with probes specific for the

W. Rens; L. Torosantucci; F. Degrassi; M. A. Ferguson-Smith

2006-01-01

160

Clinical Design Sciences: A View from Sister Design Efforts.  

ERIC Educational Resources Information Center

Asserts that the social sciences are clinical-like endeavors, and the way that "sister" fields discover and validate their results may inform research practice in education. Describes three fields of design that confront similar societal demands for improvement (engineering product design, research on the diffusion of innovations, and management…

Zaritsky, Raul; Kelly, Anthony E.; Flowers, Woodie; Rogers, Everett; O'Neill, Patrick

2003-01-01

161

Preparation and Staining of Mammal Cells to View Sister Chromatids  

NSDL National Science Digital Library

This activity was developed in the laboratory of Dr. Pablo Arenaz at the University of Texas at El Paso during a summer teacher research fellowship program sponsored by the American Society For Cell Biology. This protocol allows you to see chromatids in mammal tissue. The protocol below was used to observe sister chromatid exchanges in Chinese Hamster Ovary Cells (Cell line AA8).

Charles E. Geach (Technology & Information Systems REV)

1994-07-30

162

Doing me! Sisters Working Together for a Healthy Mind and Body  

E-print Network

that body image, family roles spiritual and religious beliefs social-culturalroles, spiritual and religious beliefs, social cultural history, identity, and food preference are important factors to consider an enormous gap between what we know can maximize the quality of health care and what is currentlymaximize

Illinois at Chicago, University of

163

Observations of the Atomic Structure of Tensile and Compressive Twin Boundaries and Twin-Twin Interactions in Zirconium  

NASA Astrophysics Data System (ADS)

The boundary structures of twins in the hexagonal close-packed metal zirconium were studied. High-resolution transmission electron microscopy was used to characterize the boundary structure of (T1), (T2), and (C1) twins on the atomic level. Basal-prismatic (B-P) plane faceting is observed along the T1 twin boundaries, matching previous observations of T1 twins in magnesium. C1 twins are observed to form basal-pyramidal (B-Py) facets along otherwise perfect twin planes. T2 twins exhibit faceting that aligns prism planes with second-order pyramidal planes across the boundary (P-Py facets). As a function of the crystallography, T2 twins appear less likely to accommodate large deviations from perfect twin planes by P-Py faceting alone, and may rely on small dislocation-accommodated facets to achieve arbitrary boundary planes. The structure of these boundaries, specifically the modes by which faceting is permitted, has a direct impact on boundary mobility. In addition, the boundary structure of two C1 twins during a twin-twin interaction event is observed, and is compared to previous observations of tensile twin-twin interactions in magnesium.

Morrow, Benjamin M.; McCabe, Rodney J.; Cerreta, Ellen K.; Tomé, Carlos N.

2014-12-01

164

Healthy Eating  

NSDL National Science Digital Library

Studenst will understand how a healthy diet and exercise can increase the likelihood of physical and mental wellness Read and discover what your body needs to function with the first two websites: Body Needs and Dining Decisions, Feel free to explore, discover how many servings you need of each food group and how to read nutrition labels. After you feel comfortable with the subject, go to the final ...

Ms. Ford

2011-12-11

165

Successful skin homografting from an identical twin in a severely burned patient.  

PubMed

Flame burns are a serious condition and usually have high morbidity and mortality because they affect large areas of the body surface as well as the lungs. In these patients, it is especially difficult to find healthy skin for grafting if they have more than 70% third-degree burns. Repeated autografting or synthetic wound care materials are the only treatment options to cover burned areas. Partial-thickness skin grafting from the patient's identical twin sibling may be an alternative treatment option, if possible. Here, we report a patient with severe flame injury treated with skin from his identical twin. The patient had third-degree burns covering 70% of his body surface. Initial treatment consisted of fluid and electrolyte replacement, daily wound care, and surgical debridements, as well as nutritional support. After initial treatment, we performed a successful skin grafting from his identical twin. Skin grafting between identical twins might be an alternate method for severely burned patients. PMID:23811789

Turk, Emin; Karagulle, Erdal; Turan, Hale; Oguz, Hakan; Abali, Ebru Sakallioglu; Ozcay, Necdet; Moray, Gokhan; Haberal, Mehmet

2014-01-01

166

Conjoined hearts in thoracopagus twins.  

PubMed

This study aimed to identify the anatomic and pathologic structural cardiac abnormalities in conjoined twins and to focus on those that have prevented the successful separation of conjoined hearts. A retrospective review was undertaken to examine consecutive cases of thoracopagus conjoined twins with conjoined hearts evaluated at The Children's Hospital of Philadelphia from 1 January 1980 through 6 October 2008. The records included autopsy and surgical findings as well as clinical reports. The study group included nine sets of conjoined twins with a mean gestational age at birth of 33.8 ± 5.5 weeks. Three twin pairs were stillborn. Five twin pairs died afterward. One pair died of cardiopulmonary failure. The median age at death was 22 days (range, 0-345 days). Major congenital heart disease was present in 94.4% (17/18) of the hearts, and 72.2% (13/18) of the hearts had single-ventricle physiology. Total anomalous pulmonary venous return occurred in 39% (7/18) of the cases. The clinical outcome for thoracopagus twins with conjoined hearts remains poor because of inability to separate conjoined and single ventricles. Surgical nonintervention and palliative care should be strongly considered for these patients. PMID:22271385

Thomas Collins, R; Weinberg, Paul M; Gruber, Peter J; St John Sutton, Martin G

2012-02-01

167

Insulin Resistance in the Sisters of Women with Polycystic Ovary Syndrome: Association with  

E-print Network

, Pennsylvania 19104; and Department of Statistics, Harvard University (S.C.W.), Cambridge, Massachusetts 02138. The magnitude of obesity also differed significantly among the groups of sisters. The PCOS sisters were significantly more obese than all the other groups, and the HA sisters were more obese than the UA sis- ters. We

Wang, Steve C.

168

A general method to determine twinning elements  

PubMed Central

The fundamental theory of crystal twinning has been long established, leading to a significant advance in understanding the nature of this physical phenomenon. However, there remains a substantial gap between the elaborate theory and the practical determination of twinning elements. This paper proposes a direct and simple method – valid for any crystal structure and based on the minimum shear criterion – to calculate various twinning elements from the experimentally determined twinning plane for Type I twins or the twinning direction for Type II twins. Without additional efforts, it is generally applicable to identify and predict possible twinning modes occurring in a variety of crystalline solids. Therefore, the present method is a promising tool to characterize twinning elements, especially for those materials with complex crystal structure. PMID:22477779

Zhang, Yudong; Li, Zongbin; Esling, Claude; Muller, Jacques; Zhao, Xiang; Zuo, Liang

2010-01-01

169

Sunset over Twin Peaks  

NASA Technical Reports Server (NTRS)

This image was taken by the Imager for Mars Pathfinder (IMP) about one minute after sunset on Mars on Sol 21. The prominent hills dubbed 'Twin Peaks' form a dark silhouette at the horizon, while the setting sun casts a pink glow over the darkening sky. The image was taken as part of a twilight study which indicates how the brightness of the sky fades with time after sunset. Scientists found that the sky stays bright for up to two hours after sunset, indicating that Martian dust extends very high into the atmosphere.

Mars Pathfinder is the second in NASA's Discovery program of low-cost spacecraft with highly focused science goals. The Jet Propulsion Laboratory, Pasadena, CA, developed and manages the Mars Pathfinder mission for NASA's Office of Space Science, Washington, D.C. JPL is an operating division of the California Institute of Technology (Caltech). The Imager for Mars Pathfinder (IMP) was developed by the University of Arizona Lunar and Planetary Laboratory under contract to JPL. Peter Smith is the Principal Investigator.

1997-01-01

170

The Twin Jet Nebula  

NASA Technical Reports Server (NTRS)

M2-9 is a striking example of a 'butterfly' or a bipolar planetary nebula. Another more revealing name might be the 'Twin Jet Nebula.' If the nebula is sliced across the star, each side of it appears much like a pair of exhausts from jet engines. Indeed, because of the nebula's shape and the measured velocity of the gas, in excess of 200 miles per second, astronomers believe that the description as a super-super-sonic jet exhaust is quite apt. This is much the same process that takes place in a jet engine: The burning and expanding gases are deflected by the engine walls through a nozzle to form long, collimated jets of hot air at high speeds. M2-9 is 2,100 light-years away in the constellation Ophiucus. The observation was taken Aug. 2, 1997 by the Hubble telescope's Wide Field and Planetary Camera 2. In this image, neutral oxygen is shown in red, once-ionized nitrogen in green, and twice-ionized oxygen in blue.

1997-01-01

171

Researches on the Twin Prime Problem  

E-print Network

Twin prime number problem is mainly the structure of the twin prime numbers and whether there are infinitely many prime twins group. In this paper, by constructing a special cluster number set(see formula(2.3)in the paper), proves that the number of set number of the first n columns set the intersection of the minimum number of q is decision of the prime twins (q, q+2), and the minimum number of series is divergent(see Theorem 2).The main rezults are Theorem 2,Theorem 3 and Theorem 4.Prime twins so thoroughly proved there must be infinitely many groups of twin prime conjecture.

Zhang Baoshan

2014-05-13

172

32. VIEW OF TWIN FALLS MAIN CANAL FROM VICINITY OF ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

32. VIEW OF TWIN FALLS MAIN CANAL FROM VICINITY OF PROPOSED POWER CANAL, LOOKING UPSTREAM. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

173

27. VIEW OF TWIN FALLS MAIN CANAL HEADGATE WITH CANAL ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

27. VIEW OF TWIN FALLS MAIN CANAL HEADGATE WITH CANAL BRIDGE IN DISTANCE; LOOKING SOUTHWEST. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

174

26. DETAIL OF HEADGATE HOIST MACHINERY, TWIN FALLS MAIN CANAL. ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

26. DETAIL OF HEADGATE HOIST MACHINERY, TWIN FALLS MAIN CANAL. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

175

23. TWIN FALLS MAIN CANAL HEADWORKS WITH MILNER DAM IN ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

23. TWIN FALLS MAIN CANAL HEADWORKS WITH MILNER DAM IN DISTANCE; LOOKING NORTHEAST. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

176

22. TWIN FALLS MAIN CANAL HEADWORKS WITH MILNER DAM IN ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

22. TWIN FALLS MAIN CANAL HEADWORKS WITH MILNER DAM IN DISTANCE; LOOKING EAST. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

177

127. COTTONWOOD CUT AREA, TWIN FALLS COUNTY, SOUTH OF KIMBERLY, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

127. COTTONWOOD CUT AREA, TWIN FALLS COUNTY, SOUTH OF KIMBERLY, IDAHO; NORTH VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

178

128. COTTONWOOD CUT, TWIN FALLS COUNTY, SOUTH OF KIMBERLY, IDAHO; ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

128. COTTONWOOD CUT, TWIN FALLS COUNTY, SOUTH OF KIMBERLY, IDAHO; NORTH VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

179

125. COTTONWOOD CUT AREA, TWIN FALLS COUNTY, SOUTH OF KIMBERLY, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

125. COTTONWOOD CUT AREA, TWIN FALLS COUNTY, SOUTH OF KIMBERLY, IDAHO; SOUTH VIEW OF CANAL. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

180

30. VIEW OF TWIN FALLS MAIN CANAL FROM BRIDGE LOOKING ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

30. VIEW OF TWIN FALLS MAIN CANAL FROM BRIDGE LOOKING WEST DOWNSTREAM. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

181

31. VIEW OF TWIN FALLS MAIN CANAL BRIDGE FROM DOWNSTREAM ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

31. VIEW OF TWIN FALLS MAIN CANAL BRIDGE FROM DOWNSTREAM LOOKING UPSTREAM. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

182

29. VIEW OF TWIN FALLS MAIN CANAL BRIDGE FROM UPSTREAM ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

29. VIEW OF TWIN FALLS MAIN CANAL BRIDGE FROM UPSTREAM LOOKING DOWNSTREAM. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

183

24. TWIN FALLS MAIN CANAL HEADWORKS, DOWNSTREAM LOOKING TOWARD THE ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

24. TWIN FALLS MAIN CANAL HEADWORKS, DOWNSTREAM LOOKING TOWARD THE EAST. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

184

108. MURTAUGH LAKE HEADGATES, TWIN FALLS COUNTY, SOUTH OF MURTAUGH, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

108. MURTAUGH LAKE HEADGATES, TWIN FALLS COUNTY, SOUTH OF MURTAUGH, IDAHO; OVERALL VIEW SOUTH. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

185

100. MURTAUGH LAKE HEADGATES, TWIN FALLS COUNTY, SOUTH OF MURTAUGH, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

100. MURTAUGH LAKE HEADGATES, TWIN FALLS COUNTY, SOUTH OF MURTAUGH, IDAHO; SOUTH VIEW OF HEADGATES. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

186

107. MURTAUGH LAKE, TWIN FALLS COUNTY, SOUTH OF MURTAUGH, IDAHO; ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

107. MURTAUGH LAKE, TWIN FALLS COUNTY, SOUTH OF MURTAUGH, IDAHO; WEST VIEW OF LAKE. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

187

Calcific periarthritis as the only clinical manifestation of hypophosphatasia in middle-aged sisters.  

PubMed

Hypophosphatasia (HPP) is the inborn error of metabolism that features low serum alkaline phosphatase (ALP) activity caused by loss-of-function mutation(s) within the gene for the tissue nonspecific isoenzyme of ALP (TNSALP). In HPP, extracellular accumulation of inorganic pyrophosphate (PPi), a TNSALP substrate and inhibitor of mineralization, leads frequently to premature tooth loss and often to rickets or osteomalacia. In affected adults, the excess PPi sometimes also causes calcium pyrophosphate dihydrate (CPPD) deposition, PPi arthropathy, or pseudogout, or seemingly paradoxical deposition of hydroxyapatite crystals in ligaments or around joints when the condition is called calcific periarthritis (CP). We report three middle-aged sisters with CP as the only clinical manifestation of HPP. Each presented during early adult life with recurrent episodes of pain principally around the shoulders, elbows, wrists, hips, or Achilles tendon. Otherwise, they were in good health, including no history of unusual dental disease, fractures, or pseudofractures. Calcific deposits were identified in symptomatic areas principally by ultrasonographic assessment but also confirmed radiographically. All three sisters had low serum levels of total and bone-specific ALP, hyperphosphatemia, and increased serum concentrations of the TNSALP substrate pyridoxal 5'-phosphate together characteristic of HPP. Mutation analysis revealed that each carried a single unique 18-bp duplication within TNSALP (c.188_205dup18, p.Gly63_Thr68dup) as did two of their healthy sons and their mother, who was without signs of CPPD deposition or CP but had knee osteoarthritis. We find that CP can be the only complication of HPP in adults. Thus, multiple juxta-articular deposits of hydroxyapatite causing CP may be a useful sign of HPP, especially when the CP is familial. PMID:24123110

Guańabens, Núria; Mumm, Steven; Möller, Ingrid; González-Roca, Eva; Peris, Pilar; Demertzis, Jennifer L; Whyte, Michael P

2014-04-01

188

Healthy Air at School  

MedlinePLUS

... Air > At School > Healthy Air at School Healthy Air at School To grow into healthy adults, our children need ... to handle more difficult problems. How to Keep Air at School Healthy Want to get involved in protecting the ...

189

Long term outcome of twin-twin transfusion syndrome  

PubMed Central

AIMS—To compare the perinatal mortality and morbidity of infants with twin-twin transfusion syndrome (TTTS) with those of gestation matched twin controls and to assess the neurodevelopmental outcome of surviving twins with TTTS.?METHODS—A cohort of 17 consecutive pregnancies with TTTS was enrolled over three years together with gestation matched twin pregnancies unaffected by TTTS. Serial amnioreduction for the TTTS pregnancies was performed as appropriate. Perinatal death and neonatal morbidities were recorded for both the TTTS cohort and controls. The TTTS survivors had neurodevelopmental follow up to at least 2 years of age.?RESULTS—In 12 of the pregnancies, serial amniocenteses were performed, but, in five, the infants were born before intervention. The mean gestational age at delivery was 29.1 weeks (range 23-36). There were five intrauterine deaths in the TTTS cohort and six neonatal deaths (survival 68%). In the control group, there was one intrauterine death and five neonatal deaths (survival 82%). Infants in the TTTS group had a greater requirement for inotropes (p = 0.04) and a higher incidence of renal failure (p = 0.005). Periventricular leucomalacia and cerebral atrophy were seen in 17% of the TTTS group, but none of the controls (p = 0.03). The 23 surviving TTTS infants were all followed up, with 22% having significant neurological morbidity: cerebral palsy and global developmental delay.?CONCLUSIONS—Twins with TTTS have high perinatal mortality and neonatal morbidity, and long term neurodevelopmental morbidity in survivors is high. Further investigation into the pathogenesis and management of TTTS is required.?? PMID:11040163

Cincotta, R; Gray, P; Phythian, G; Rogers, Y; Chan, F

2000-01-01

190

Purine nucleoside phosphorylase deficiency with fatal course in two sisters.  

PubMed

Purine nucleoside phosphorylase (PNP) deficiency is a rare combined immunodeficiency disorder presenting with clinically recurrent infections, failure to thrive, various neurological disorders, malignancies, and autoimmune diseases. Here, we report two sisters with a fatal course of PNP deficiency due to delay in diagnosis. The first patient developed a liver abscess by Aspergillus fumigatus and the second patient developed Mycobacterium tuberculosis complex lymphadenitis and probable pulmonary tuberculosis due to disseminated BCG infection. The patients also suffered from sclerosing cholangitis. Mutation analysis of the PNP gene from both sisters revealed a homozygous mutation for a G>A at nucleotide 349 (349 G>A transition), which changes alanine 117 to theronine in exon 4 (A117T). An increased awareness of early signs, symptoms, and abnormal laboratory findings of PNP deficiency will establish the early prognosis and treatment. PMID:19657670

Aytekin, Caner; Dogu, Figen; Tanir, Gonul; Guloglu, Deniz; Santisteban, Ines; Hershfield, Michael S; Ikinciogullari, Aydan

2010-03-01

191

The template choice decision in meiosis: is the sister important?  

Microsoft Academic Search

Recombination between homologous chromosomes is crucial to ensure their proper segregation during meiosis. This is achieved\\u000a by regulating the choice of recombination template. In mitotic cells, double-strand break repair with the sister chromatid\\u000a appears to be preferred, whereas interhomolog recombination is favoured during meiosis. However, in the last year, several\\u000a studies in yeast have shown the importance of the meiotic

Mónica Pradillo; Juan L. Santos

192

8METHOXYPSORALEN AND UVA PROMOTE SISTER-CHROMATID EXCHANGES  

Microsoft Academic Search

8-Methoxypsoralen (8-MOP) and long-wave UV light (UVA, 365 nm) are now being used to treat vitiligo and psoriasis. Cultured human lymphocytes exposed to these agents in vitro show an increased infrequency of sister chromatid exchanges, related to 8-MOP-DNA photoadducts. Although these data raise questions regarding the biologic consequences of this therapeutic regimen, it is unknown whether 8-MOP and UVA cause

D. Martin Carter; Klaus Wolff; Wolfgang Schnedl

1976-01-01

193

Endocrine Disorders in Two Sisters Affected by MELAS Syndrome  

Microsoft Academic Search

A variety of endocrine and metabolic defects, including hypothalamopituitary hypofunction and diabetes mellitus, has been reported in association with mitochondrial disorders. We describe two sisters affected by mitochondrial encephalomyopathy, lactic acidosis, and strokelike episodes (MELAS) syndrome in whom DNA analysis showed an A?G transition at the 3243rd nucleotide position on the transfer RNA Leu(UUR) gene with 65% and 45% of

Paolo Balestri; Salvatore Grosso

2000-01-01

194

180. Photocopy of Photograph, Twin Falls Canal Company. E. Pettygro, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

180. Photocopy of Photograph, Twin Falls Canal Company. E. Pettygro, Photographer, date unknown. BLASTING TWIN FALLS CANAL, TWIN FALLS COUNTY; BLASTING COTTONWOOD AREA TO REPLACE FLUME BY RUNNING HIGH LINE THROUGH SOLID ROCK. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

195

150. Photocopy of drawing (taken from Twin Falls Canal Company ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

150. Photocopy of drawing (taken from Twin Falls Canal Company Surveyor's Book #363, Page 42, entitled, 'Diversion Tunnels', located in Twin Falls Canal Company office, Twin Falls, Idaho). PLAN OF DIVERSION TUNNELS, MILNER DAM. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

196

Broad phylogenomic sampling and the sister lineage of land plants.  

PubMed

The tremendous diversity of land plants all descended from a single charophyte green alga that colonized the land somewhere between 430 and 470 million years ago. Six orders of charophyte green algae, in addition to embryophytes, comprise the Streptophyta s.l. Previous studies have focused on reconstructing the phylogeny of organisms tied to this key colonization event, but wildly conflicting results have sparked a contentious debate over which lineage gave rise to land plants. The dominant view has been that 'stoneworts,' or Charales, are the sister lineage, but an alternative hypothesis supports the Zygnematales (often referred to as "pond scum") as the sister lineage. In this paper, we provide a well-supported, 160-nuclear-gene phylogenomic analysis supporting the Zygnematales as the closest living relative to land plants. Our study makes two key contributions to the field: 1) the use of an unbiased method to collect a large set of orthologs from deeply diverging species and 2) the use of these data in determining the sister lineage to land plants. We anticipate this updated phylogeny not only will hugely impact lesson plans in introductory biology courses, but also will provide a solid phylogenetic tree for future green-lineage research, whether it be related to plants or green algae. PMID:22253761

Timme, Ruth E; Bachvaroff, Tsvetan R; Delwiche, Charles F

2012-01-01

197

Southall Black Sisters. Hannana Siddiqui speaks to Rasna Warah.  

PubMed

Southall Black Sisters, an organization for Asian and Afro-Caribbean women in Great Britain, was established in 1979 at the height of anti-racist protests to address the otherwise neglected issue of women's oppression. The group has campaigned against discriminatory immigration laws, illegal virginity tests at Heathrow airport, domestic violence, and other issues of particular concern to British Asian women. Women who migrate to England for an arranged marriage must remain with their husband at least 1 year or face deportation and denial of any public assistance, placing them at risk of unreported domestic violence. Southall Black Sisters has attempted to raise the public consciousness about domestic violence as a criminal issue and garner support for Asian women who leave abusive husbands. However, no support has been forthcoming from the anti-racist movement, which fears that publicity on domestic violence will create a racist backlash against Asian men. More support has been available for the group's campaign to protect battered women who kill their husbands by removing from the law on provocation the need for an immediate response. Another campaign has involved protests against "bounty hunters" hired by Asian families to return girls who have escaped from arranged marriages in their home country or sexual abuse within their family. Southall Black Sisters attributes many of the problems faced by its clients to a rise in religious fundamentalism and Muslim attempts to reverse the gains of the feminist movement. PMID:12287625

Warah, R

1994-01-01

198

Brief Report: Autistic Traits in Twins vs. Non-Twins--A Preliminary Study  

ERIC Educational Resources Information Center

Previous studies have suggested that among affected sib pairs with autism there is an increase in the frequency of twins over what would be expected in comparison to the prevalence of twins in the general population. In this study we sought to determine whether "sub-threshold" autistic traits were more pronounced in twins than in non-twins. The…

Ho, Alexander; Todd, Richard D.; Constantino, John N.

2005-01-01

199

Impact of Twin-to-Twin Transfusion Syndrome, Preterm Birth, and Vision Loss on Development  

ERIC Educational Resources Information Center

This study compared the developmental outcomes of twin boys (one who is blind and one who is sighted) who were born prematurely and diagnosed with twin-to-twin transfusion syndrome (TTTS) at age 24 months. The results indicate a disparity in the developmental outcomes of the twins. Although the medical risk factors that are associated with TTTS…

Celeste, Marie

2005-01-01

200

49 CFR 372.221 - Twin Cities.  

Code of Federal Regulations, 2013 CFR

...Transportation 5 2013-10-01 2013-10-01 false Twin Cities. 372.221 Section 372.221 Transportation...ZONES, AND TERMINAL AREAS Commercial Zones § 372.221 Twin Cities. For the purpose of determining commercial...

2013-10-01

201

The twin paradox on the photon sphere  

E-print Network

We consider a new version of the twin paradox. The twins move along the same circular free photon path around the Schwarzschild center. In this case, despite their different velocities, all twins have the same non-zero acceleration. On the circular photon path, the symmetry between the twins situations is broken not by acceleration (as it is in the case of the classic twin paradox), but by the existence of an absolute standard of rest (timelike Killing vector). The twin with the higher velocity with respect to the standard of rest is younger on reunion. This closely resembles the case of periodic motions in compact (non-trivial topology) 3-D space recently considered in the context of the twin paradox by Barrow and Levin, except that there accelerations of all twins were equal to zero, and that in the case considered here, the 3-D space has trivial topology.

Marek A. Abramowicz; Stanislaw Bajtlik; Wlodek Kluzniak

2006-12-11

202

49 CFR 372.221 - Twin Cities.  

Code of Federal Regulations, 2012 CFR

...Transportation 5 2012-10-01 2012-10-01 false Twin Cities. 372.221 Section 372.221 Transportation...ZONES, AND TERMINAL AREAS Commercial Zones § 372.221 Twin Cities. For the purpose of determining commercial...

2012-10-01

203

49 CFR 372.221 - Twin Cities.  

...Transportation 5 2014-10-01 2014-10-01 false Twin Cities. 372.221 Section 372.221 Transportation...ZONES, AND TERMINAL AREAS Commercial Zones § 372.221 Twin Cities. For the purpose of determining commercial...

2014-10-01

204

49 CFR 372.221 - Twin Cities.  

Code of Federal Regulations, 2011 CFR

...Transportation 5 2011-10-01 2011-10-01 false Twin Cities. 372.221 Section 372.221 Transportation...ZONES, AND TERMINAL AREAS Commercial Zones § 372.221 Twin Cities. For the purpose of determining commercial...

2011-10-01

205

CONJOINED TWIN ADULT SHRIMP (DECAPODA: PENAEIDAE)  

E-print Network

NOTES CONJOINED TWIN ADULT SHRIMP (DECAPODA: PENAEIDAE) A two-headed roughback shrimp by preservation. Antennules, anten- FIGURE I.-Conjoined twin Trackype1UUi'1U1 simi/is in diagrammatic lateral view

206

Congenital tracheobronchial stenosis in monozygotic twins  

Microsoft Academic Search

  \\u000a \\u000a Conclusion This case report shows that tracheobronchial stenosis may present in monozygotic twins. The pattern of malformation in twins\\u000a differs from cases described previously.

K. S. Wong; R. Lien; T. Y. Lin

1998-01-01

207

Monozygotic twins discordant for trisomy 13.  

PubMed

Monozygotic twins with discordant karyotypes are rare. We report a case of monozygotic twins discordant for trisomy 13 by amniocyte karyotypes. Ultrasound revealed multiple congenital anomalies in Twin A (47,XY,+13), none in Twin B (46,XY), and monochorionic-diamniotic placentation. Zygosity testing performed both prenatally and after birth supported monozygosity. Twin A died in the neontal period. Twin B survived and had normal physical examination, but peripheral blood karyotype revealed 20% mosaicism for trisomy 13. Monochorionic-diamniontic placentation with vascular anastomoses was confirmed by pathological examination. In this paper, we discuss the various mechanisms by which monozygotic twins may have discordant karyotypes. The surviving twin, structurally and developmentally normal at 6 months of age, will be monitored for potential complications of uniparental disomy of chromosome 13 and trisomy 13 mosaicism. PMID:22460600

Ramsey, K Wong; Slavin, T P; Graham, G; Hirata, G I; Balaraman, V; Seaver, L H

2012-04-01

208

A Little Twin Higgs Model  

SciTech Connect

We present a twin Higgs model based on left-right symmetry with a tree level quartic. This is made possible by extending the symmetry of the model to include two Z_2 parities, each of which is sufficient to protect the Higgs from getting a quadratically divergent mass squared. Although both parities are brokenexplicitly, the symmetries that protect the Higgs from getting a quadratically divergent mass are broken only collectively. The quadratic divergences of the Higgs mass are thus still protected at one loop. We find that the fine-tuning in this model is reduced substantially compared to the original left-right twin Higgs model. This mechanism can also be applied to the mirror twin Higgs model to get a significant reduction of the fine-tuning, while keeping the mirror photon massless.

Goh, Hock-Seng; Goh, Hock-Seng; Krenke, Christopher A.

2007-07-25

209

Deformation twinning in nanocrystalline Pd  

NASA Astrophysics Data System (ADS)

Defect structures of plastically deformed nanocrystalline Pd investigated by high-resolution transmission electron microscopy are presented. Material with an average grain size of about 15 nm was prepared by inert-gas condensation, and this was plastically deformed by cold rolling up to a true strain of 0.32 at a strain rate of about 0.3 s-1. Abundant deformation twinning on {111} planes was found and Shockley partial dislocations identified. Remarkably, in each grain, twinning occurs only on a single set of parallel planes. This implies that only one out of the five independent slip systems required for the general deformation of a grain is active, a finding which suggests that grain rotation and grain-boundary sliding must be active together with twinning.

Rösner, Harald; Jürgen; Jörg

2004-05-01

210

Simulations of Stress-induced Twinning and De-twinning: a Phase-field Model  

SciTech Connect

Twinning in metals is a major plastic deformation mode. Here we present a phase-field model to describe twin formation and evolution in a polycrystalline FCC metal under loading and unloading. The model assumes that the twin nucleation, growth and de-twinning is a process of partial dislocation nucleation and slip on successive habit planes. Stacking fault energies, energy pathways ( surfaces), critical shear stresses for the formation of stacking faults, and dislocation core energies are used to construct the thermodynamic model. The simulation results demonstrate that the model is able to predict the nucleation of twins and partial dislocations as well as the morphology of the twin nuclei, and reasonably to describe twin growth and interaction. The twin microstructures at grain boundaries are in agreement with experimental observation . It is found that de-twinning occurs during unloading in performed simulations. However, strong dependence of twin structure evolution on loading history is observed.

Hu, Shenyang Y.; Henager, Charles H.; Chen , L.Q.

2010-11-01

211

Diastolic Cardiac Pathology and Clinical Twin-Twin Transfusion Syndrome in Monochorionic/Diamniotic Twins  

PubMed Central

Objective to identify differences in echocardiographic profiles of monochorionic/diamniotic pregnancies with early or mild twin-twin transfusion syndrome (TTTS), compared to monochorionic/diamniotic twins affected only by discordant growth or discordant fluid. Study Design retrospective evaluation of sonograms and echocardiograms of twin pregnancies referred for suspected TTTS. Results 112 monochorionic/diamniotic pairs were studied. 41 did not have/develop TTTS, 61 had Stage I/II TTTS. Ten developed TTTS after initially not meeting criteria. TTTS recipients had a higher rate of venous Doppler or tricuspid inflow abnormalities than purported “recipients” in non-TTTS pregnancies (86% vs. 37%, P<0.001). TTTS recipients had shorter tricuspid inflow duration/RR intervals than non-TTTS fetuses (32+/?6% versus 37+/?4%, P<0.001). Logistic regression and recursive partitioning identified shorter tricuspid inflow duration, longer isovolumic relaxation, and ductus venosus abnormality associated with TTTS. Conclusion Diastolic pathology, specifically shorter tricuspid inflow duration, may be considered a hallmark of TTTS distinguishing these pregnancies from other monochorionic/diamniotic twin complications. PMID:21909155

Moon-Grady, Anita J.; Rand, Larry; Gallardo, Salvador; Gosnell, Kristen; Lee, Hanmin; Feldstein, Vickie A.

2011-01-01

212

Phospholipids and insulin resistance in psychosis: a lipidomics study of twin pairs discordant for schizophrenia  

PubMed Central

Background Several theories have been proposed to conceptualize the pathological processes inherent to schizophrenia. The 'prostaglandin deficiency' hypothesis postulates that defective enzyme systems converting essential fatty acids to prostaglandins lead to diminished levels of prostaglandins, which in turn affect synaptic transmission. Methods Here we sought to determine the lipidomic profiles associated with schizophrenia in twin pairs discordant for schizophrenia as well as unaffected twin pairs. The study included serum samples from 19 twin pairs discordant for schizophrenia (mean age 51 ± 10 years; 7 monozygotic pairs; 13 female pairs) and 34 age and gender matched healthy twins as controls. Neurocognitive assessment data and gray matter density measurements taken from high-resolution magnetic resonance images were also obtained. A lipidomics platform using ultra performance liquid chromatography coupled to time-of-flight mass spectrometry was applied for the analysis of serum samples. Results In comparison to their healthy co-twins, the patients had elevated triglycerides and were more insulin resistant. They had diminished lysophosphatidylcholine levels, which associated with decreased cognitive speed. Conclusions Our findings may be of pathophysiological relevance since lysophosphatidylcholines, byproducts of phospholipase A2-catalyzed phospholipid hydrolysis, are preferred carriers of polyunsaturated fatty acids across the blood-brain barrier. Furthermore, diminishment of lysophosphatidylcholines suggests that subjects at risk of schizophrenia may be more susceptible to infections. Their association with cognitive speed supports the view that altered neurotransmission in schizophrenia may be in part mediated by reactive lipids such as prostaglandins. PMID:22257447

2012-01-01

213

Diagnosis of Twin Zygosity by Mailed Questionnaire  

Microsoft Academic Search

A deterministic questionnaire method for zygosity determination is developed for use in epidemiological studies of adult twins. It is based on the answers of both members of a twin pair to two questions on similarity and confusion in childhood. The algorithm of the method is used to determine the zygosity status of a twin pair at two different levels of

Seppo Sarna; Jaakko Kaprio; Pertti Sistonen; Markku Koskenvuo

1978-01-01

214

Research With Twins: The Concept of Emergenesis  

Microsoft Academic Search

Preliminaty findings from an on-going study of monozygotic twins reared apart (MZA) and data from a larger sample of twins reared together (MZT and DZT), indicate a surprisingly strong influence of genetic variation on aptitudes, psychophysiological characteristics, personality traits and even dimensions of atti- tude and interest. For some of these variables, MZT and MZA twins show high intra-class correlations

David T. Lykken

1982-01-01

215

Twin Cities Metro Advanced Practice Center  

E-print Network

Twin Cities Metro Advanced Practice Center Food Safety Self Inspection Checklist #12;Table-20 Vietnamese..............................21-22 #12;Food Safety Self Inspection Checklist Twin Cities Metro has expired. #12;Food Safety Self Inspection Checklist Twin Cities Metro Advanced Practice Center

216

On Teaching About Twins and Time  

ERIC Educational Resources Information Center

Discusses a four-step instructional presentation in which the twin on the earth is demonstrated older than the twin aboard a spaceship on the basis of the relativistic Doppler effect. Concludes that both twins can meet again at the same place in space at the expense of time. (CC)

Hewitt, Paul G.

1973-01-01

217

Monozygotic Twin Wolves with Divergent Life Histories  

Microsoft Academic Search

Genetic evidence for monozygotic (identical) twinning in mammalian species is rare in the literature. Here we report what may be the first pair of monozygotic twins identified in a wild caniform carnivore, the grey wolf (Canis lupus). One of these individuals remained in its natal population of Banks Island, Northwest Territories, Canada, while its twin migrated across the polar sea

LINDSEY CARMICHAEL; JOHN A. NAGY; CURTIS STROBECK

2008-01-01

218

Cardiac dysfunction in twin–twin transfusion syndrome: a prospective, longitudinal study  

Microsoft Academic Search

Objective: To use serial echocardiography to evaluate prospectively the cardiac dysfunction in twin–twin transfusion syndrome and determine its clinical course and outcome.Methods: Twin pregnancies presenting in the second trimester with sonographic evidence of twin–twin transfusion syndrome were managed with therapeutic reduction amniocenteses. Gestational age at diagnosis and delivery, number of amniocenteses performed, volume of amniotic fluid withdrawn, placentation, birth weight,

Lynn L Simpson; Gerald R Marx; Eman A Elkadry; Mary E D’alton

1998-01-01

219

Genetic determination of islet cell autoimmunity in monozygotic twin, dizygotic twin, and non-twin siblings of patients with type 1 diabetes: prospective twin study  

PubMed Central

Objective To test the hypothesis that non-diabetic dizygotic and monozygotic twin siblings of patients with type 1 diabetes have a similar high prevalence of islet cell autoantibodies, thus suggesting that islet cell autoimmunity is mainly environmentally determined. Design Prospective twin study. Setting Two specialist centres for diabetes in the United States. Participants Non-diabetic monozygotic twin (n=53), dizygotic twin (n=30), and non-twin (n=149) siblings of patients with type 1 diabetes; 101 controls. Main outcome measures Analysis of progression to diabetes and expression of anti-islet autoantibodies. Results Monozygotic twin siblings had a higher risk of progression to diabetes (12/53) than dizygotic twin siblings (0/30; P<0.005). At the last follow up 22 (41.5%) monozygotic twin siblings expressed autoantibodies compared with 6 (20%) dizygotic twin siblings (P<0.05), 16 (10.7%) non-twin siblings (P<0.0001), and 6 (5.9%) controls (P<0.0001). Monozygotic twin siblings expressed multiple (?2) antibodies more often than dizygotic twin siblings (10/38 v 1/23; P<0.05). By life table analysis the probability of developing positive autoantibodies was higher among the monozygotic twin siblings bearing the diabetes associated HLA DQ8/DQ2 genotype than in those without this genotype (64.2% (95% confidence interval 32.5% to 96%) v 23.5% (7% to 40%) at 10 years of discordance; P<0.05). Conclusion Monozygotic and dizygotic twins differ in progression to diabetes and expression of islet cell autoantibodies. Dizygotic twin siblings are similar to non-twin siblings. These two observations suggest that genetic factors play an important part in determination of islet cell autoimmunity, thus rejecting the hypothesis. In addition, there is a high penetrance of islet cell autoimmunity in DQ8/DQ2 monozygotic twin siblings. Key messagesMonozygotic twin siblings of patients with type 1 diabetes have a higher risk of progression to diabetes and of expressing islet cell antibodies than dizygotic twin and non-twin siblingsMonozygotic twins with the HLA genotype DQ8/DQ2 have a high risk of expression of islet cell autoimmunity and progression to diabetesIslet cell autoimmunity seems to be predominantly genetically determined PMID:10074012

Redondo, Maria J; Rewers, Marian; Yu, Liping; Garg, Satish; Pilcher, Colleen C; Elliott, Robert B; Eisenbarth, George S

1999-01-01

220

A Powerful Twin Arrives  

NASA Astrophysics Data System (ADS)

First Images from FORS2 at VLT KUEYEN on Paranal The first, major astronomical instrument to be installed at the ESO Very Large Telescope (VLT) was FORS1 ( FO cal R educer and S pectrograph) in September 1998. Immediately after being attached to the Cassegrain focus of the first 8.2-m Unit Telescope, ANTU , it produced a series of spectacular images, cf. ESO PR 14/98. Many important observations have since been made with this outstanding facility. Now FORS2 , its powerful twin, has been installed at the second VLT Unit Telescope, KUEYEN . It is the fourth major instrument at the VLT after FORS1 , ISAAC and UVES.. The FORS2 Commissioning Team that is busy installing and testing this large and complex instrument reports that "First Light" was successfully achieved already on October 29, 1999, only two days after FORS2 was first mounted at the Cassegrain focus. Since then, various observation modes have been carefully tested, including normal and high-resolution imaging, echelle and multi-object spectroscopy, as well as fast photometry with millisecond time resolution. A number of fine images were obtained during this work, some of which are made available with the present Press Release. The FORS instruments ESO PR Photo 40a/99 ESO PR Photo 40a/99 [Preview - JPEG: 400 x 345 pix - 203k] [Normal - JPEG: 800 x 689 pix - 563kb] [Full-Res - JPEG: 1280 x 1103 pix - 666kb] Caption to PR Photo 40a/99: This digital photo shows the twin instruments, FORS2 at KUEYEN (in the foreground) and FORS1 at ANTU, seen in the background through the open ventilation doors in the two telescope enclosures. Although they look alike, the two instruments have specific functions, as described in the text. FORS1 and FORS2 are the products of one of the most thorough and advanced technological studies ever made of a ground-based astronomical instrument. They have been specifically designed to investigate the faintest and most remote objects in the universe. They are "multi-mode instruments" that may be used in several different observation modes. FORS2 is largely identical to FORS1 , but there are a number of important differences. For example, it contains a Mask Exchange Unit (MXU) for laser-cut star-plates [1] that may be inserted at the focus, allowing a large number of spectra of different objects, in practice up to about 70, to be taken simultaneously. Highly sophisticated software assigns slits to individual objects in an optimal way, ensuring a great degree of observing efficiency. Instead of the polarimetry optics found in FORS1 , FORS2 has new grisms that allow the use of higher spectral resolutions. The FORS project was carried out under ESO contract by a consortium of three German astronomical institutes, the Heidelberg State Observatory and the University Observatories of Göttingen and Munich. The participating institutes have invested a total of about 180 man-years of work in this unique programme. The photos below demonstrate some of the impressive possibilities with this new instrument. They are based on observations with the FORS2 standard resolution collimator (field size 6.8 x 6.8 armin = 2048 x 2048 pixels; 1 pixel = 0.20 arcsec). In addition, observations of the Crab pulsar demonstrate a new observing mode, high-speed photometry. Protostar HH-34 in Orion ESO PR Photo 40b/99 ESO PR Photo 40b/99 [Preview - JPEG: 400 x 444 pix - 220kb] [Normal - JPEG: 800 x 887 pix - 806kb] [Full-Res - JPEG: 2000 x 2217 pix - 3.6Mb] The Area around HH-34 in Orion ESO PR Photo 40c/99 ESO PR Photo 40c/99 [Preview - JPEG: 400 x 494 pix - 262kb] [Full-Res - JPEG: 802 x 991 pix - 760 kb] The HH-34 Superjet in Orion (centre) PR Photo 40b/99 shows a three-colour composite of the young object Herbig-Haro 34 (HH-34) , now in the protostar stage of evolution. It is based on CCD frames obtained with the FORS2 instrument in imaging mode, on November 2 and 6, 1999. This object has a remarkable, very complicated appearance that includes two opposite jets that ram into the surrounding interstellar matter. This structure is produced by a machine-gu

1999-11-01

221

The Heritability of the Ring-Like Distribution of Macular Pigment Assessed in a Twin Study  

PubMed Central

Purpose. It has been suggested that ring-like patterns of macular pigment, as measured with dual wavelength autofluorescence, are observed less frequently in subjects with age-related maculopathy. We explored relative contributions of genetic and environmental factors in macular pigment optical density (MPOD) distributions using a classic twin study. Methods. As part of a previous nutritional study, 322 healthy Caucasian female twins, aged 16 to 50 (mean 40) years, underwent measurement of MPOD optical density by two-wavelength fundus autofluorescence. In the present study, the right eye MPOD profile was assessed for the presence of a ring-like pattern by two graders independently, using common criteria, with a third grader arbitrating in cases of disagreement. Concordance was calculated as 2C/(2C + D), where C is the number of twin pairs concordant, and D the number discordant, for the ring-like pattern. Also, heritability was calculated using maximum-likelihood structural equation modeling. Results. Images and zygosity data were available for 314 twins (88 monozygotic [MZ] and 69 dizygotic [DZ] pairs). The overall prevalence of the ring pattern was 25.8%. Respective concordances for MZ and DZ twins were 0.75 and 0.22. Additive genetic factors were estimated to contribute to 84.0% of the total variance (95% confidence intervals, 63.7%–94.6%). Conclusions. Concordance for MZ twins was over three times that for DZ twins, with heritability estimated at 84%, indicating that genetic factors contribute to the development of the ring structure. Studies have suggested that ring-like patterns of macular pigment can affect risk for age-related maculopathy. In a classic twin study, we found that the presence of such a pattern was highly heritable. PMID:24609627

Tariq, Ambreen; Mahroo, Omar A.; Williams, Katie M.; Liew, S. H. Melissa; Beatty, Stephen; Gilbert, Clare E.; Van Kuijk, Frederik J.; Hammond, Christopher J.

2014-01-01

222

Four twins for a paradox: On “sensitive” twins and the biological counterpart of the “twin paradox”  

Microsoft Academic Search

Monozygotic twin (MZT) epigenetic development, i.e., aging, diverges largely in time despite the initially very small genetic differences between MZTs. This fact is interpreted as a “sensitivity to initial conditions” phenomenon, a common property of either deterministic or stochastic chaotic systems. Some of the biotheoretical implications stemming from this empirical observation are briefly discussed here, while an actual measure of

Fortunato A. Ascioti

2009-01-01

223

Four twins for a paradox: On ``sensitive'' twins and the biological counterpart of the ``twin paradox''  

Microsoft Academic Search

Monozygotic twin (MZT) epigenetic development, i.e., aging, diverges largely in time despite the initially very small genetic differences between MZTs. This fact is interpreted as a ``sensitivity to initial conditions'' phenomenon, a common property of either deterministic or stochastic chaotic systems. Some of the biotheoretical implications stemming from this empirical observation are briefly discussed here, while an actual measure of

Fortunato A. Ascioti

2009-01-01

224

Healthy Family 2009: Assuring Healthy Aging  

MedlinePLUS

... Issue Past Issues Healthy Family 2009 Assuring Healthy Aging Past Issues / Winter 2009 Table of Contents For ... please turn Javascript on. 7 Smart Steps to Aging Well 1. Control Blood Pressure You can have ...

225

Pregnancy risk among the younger sisters of pregnant and childbearing adolescents.  

PubMed

There is increasing evidence that younger sisters of childbearing teenagers are at increased risk for adolescent childbearing. We critically review this research and discuss three plausible theoretical explanations (social modeling, shared parenting influences, and shared societal risk) why the younger sisters of childbearing adolescents would themselves be at risk for teenage pregnancy. Considerations for preventive interventions aimed at the younger sisters of pregnant teenagers and directions for future research are discussed. PMID:1577959

East, P L; Felice, M E

1992-04-01

226

76 FR 315 - Sisters Ranger District; Deschutes National Forest; Oregon; Popper Vegetation Management Project  

Federal Register 2010, 2011, 2012, 2013

...DEPARTMENT OF AGRICULTURE Forest Service Sisters Ranger District; Deschutes National Forest; Oregon; Popper Vegetation Management Project AGENCY: Forest Service, USDA. ACTION: Notice of intent to prepare...

2011-01-04

227

Maintaining a Healthy Weight  

MedlinePLUS

... and drink Other ways to maintian a healthy weight? Limit portion size to control calorie intake. Add ... Go4Life Maintaining a Healthy Weight Maintaining a healthy weight is important for overall health and well-being. ...

228

Sister chromatid exchange in lymphocytes from renal transplant recipients with and without cancer.  

PubMed Central

The frequency of sister chromatid exchange (SCE) was measured in peripheral blood lymphocytes from control, healthy subjects and immunosuppressed recipients of cadaveric donor kidneys with and without skin cancer. The mean SCE frequency in 43 control subjects was 9.2 per cell (range 5.4-12.3). In 30 transplant recipients with no history or evidence of cancer the mean SCE rate was 10.3 per cell (range 5.8-24.5); four (13%) of these patients had a mean SCE frequency outside the control range. In 7 transplant recipients with skin cancer, the mean SCE frequency was 14.3 per cell (range 9.1-19.9). This was significantly (P less than 0.01) higher than the mean value of control subjects. The mean SCE frequencies in 3 of these 7 patients fell within the control range and in 4 of these patients was above the control range. These results suggest that some immunosuppressed kidney transplant recipients are liable to chromosomal damage. PMID:6360193

Kelly, G. E.; Sheil, A. G.

1983-01-01

229

Why the Healing Gods Are Twins  

PubMed Central

The association of twins with health-giving powers is widespread in mythology, folklore, and religion. The Ashvins of the Rig-Veda, the classical Dioscuri, and the early Christian saints Cosmos and Damian are among the many examples of twins divinely empowered in the area of health and fertility. A characteristic set of attributes of twins recurs in different mythologies of wide distribution. In addition to healing, divine twins are often empowered with the ability to revive the dead, increase the fertility of man, animals, and crops, influence the weather, predict the future, and insure victory in battle. In some traditional societies these special attributes are thought to extend to all of the twins and their parents in the tribe. Ancient and primitive societies supposed that the birth of twins was associated with divine influence, the mother having been visited or otherwise affected by supernatural powers. A frequent explanation was that twins were the result of superfetation, a divine impregnation occurring along with that by the lawful husband. The specific powers of divine twins appear to be a reflection of the particular form of origin of twins through divine interference with the fertilization process. The twins thus share some of the powers of the divine parent, particularly those pertaining to fertility. Their dual paternity and its inherent competition is related to their martial interests as well as their ability to resolve ambivalent or ambiguous situations and predict outcomes. PMID:560764

Hankoff, Leon D.

1977-01-01

230

Fingerprint Recognition with Identical Twin Fingerprints  

PubMed Central

Fingerprint recognition with identical twins is a challenging task due to the closest genetics-based relationship existing in the identical twins. Several pioneers have analyzed the similarity between twins' fingerprints. In this work we continue to investigate the topic of the similarity of identical twin fingerprints. Our study was tested based on a large identical twin fingerprint database that contains 83 twin pairs, 4 fingers per individual and six impressions per finger: 3984 (83*2*4*6) images. Compared to the previous work, our contributions are summarized as follows: (1) Two state-of-the-art fingerprint identification methods: P071 and VeriFinger 6.1 were used, rather than one fingerprint identification method in previous studies. (2) Six impressions per finger were captured, rather than just one impression, which makes the genuine distribution of matching scores more realistic. (3) A larger sample (83 pairs) was collected. (4) A novel statistical analysis, which aims at showing the probability distribution of the fingerprint types for the corresponding fingers of identical twins which have same fingerprint type, has been conducted. (5) A novel analysis, which aims at showing which finger from identical twins has higher probability of having same fingerprint type, has been conducted. Our results showed that: (a) A state-of-the-art automatic fingerprint verification system can distinguish identical twins without drastic degradation in performance. (b) The chance that the fingerprints have the same type from identical twins is 0.7440, comparing to 0.3215 from non-identical twins. (c) For the corresponding fingers of identical twins which have same fingerprint type, the probability distribution of five major fingerprint types is similar to the probability distribution for all the fingers' fingerprint type. (d) For each of four fingers of identical twins, the probability of having same fingerprint type is similar. PMID:22558204

Yang, Xin; Tian, Jie

2012-01-01

231

Narcolepsy with Cataplexy Mimicry: The Strange Case of Two Sisters  

PubMed Central

We report on two sisters, 17 and 12 years of age, with clinical features suggesting narcolepsy with cataplexy (NC): daytime sleepiness, spontaneous and emotionally triggered sudden falls to the ground, and overweight/obesity. MSLT showed borderline sleep latency, with 1 and 0 sleep onset REM periods. HLA typing disclosed the DQB1*0602 allele. Video-polygraphy of the spells ruled out NC diagnosis by demonstrating their easy elicitation by suggestion, with wake EEG, electromyo-graphic persistence of muscle tone, and stable presence of tendon reflexes (i.e., pseudo-cataplexy), together with normal cerebrospinal hypocretin-1 levels. Our cases emphasize the need of a clear depiction of cataplexy pattern at the different ages, the usefulness of examining ictal neurophysiology, and collecting all available disease markers in ambiguous cases. Citation: Pizza F; Vandi S; Poli F; Moghadam KK; Fran-ceschini C; Bellucci C; Cipolli C; Ingravallo F; Natalini G; Mignot E; Plazzi G. Narcolepsy with cataplexy mimicry: the strange case of two sisters. J Clin Sleep Med 2013;9(6):611-612. PMID:23772196

Pizza, Fabio; Vandi, Stefano; Poli, Francesca; Moghadam, Keivan Kaveh; Franceschini, Christian; Bellucci, Claudia; Cipolli, Carlo; Ingravallo, Francesca; Natalini, Giuliana; Mignot, Emmanuel; Plazzi, Giuseppe

2013-01-01

232

Cerebral palsy in the surviving twin associated with infant death of the co-twin  

PubMed Central

BACKGROUND—Monozygotic twins are at greater risk of dying and of serious morbidity than dizygotic twins, and both are at greater risk than singletons. This is only partly explained by the higher proportion of low birthweight infants among twins.?AIM—To compare, in same sex and different sex twins, birth weight specific neonatal death rates and cerebral palsy prevalence rates in the surviving twin when the co-twin has died in infancy.?METHODS—Analysis of birth and death registration data for same sex and different sex twins for England and Wales 1993-1995 where both were live births. Death certificates of all liveborn twins who died were obtained from the Office for National Statistics. A questionnaire was sent to the general practitioners of all surviving co-twins to determine if the child had any disability.?RESULTS—The neonatal death rate in same sex twins was 25.4 and in different sex twins 18.0 per 1000 live births (death rate difference 7.4; 95% confidence interval 4.7 to 10.1; p < 0.001). The higher neonatal death rate in same sex compared with different sex twins is attributable to the higher proportion of same sex twins with low birth weight. Prevalence of cerebral palsy in the low birthweight group (< 1000 g) was marginally higher in same sex (224 per 1000) than different sex (200 per 1000) twin survivors. In the birth weight group 1000-1999 g, same sex twin survivors were at a significantly higher risk of cerebral palsy than those of different sex: 167v 21 per 1000; difference 145 (95% confidence interval 44 to 231; p < 0.01) per 1000 infant survivors.?CONCLUSION—There are two components to the cause of cerebral palsy in twins. Immaturity per se predisposes to cerebral damage. Also, same sex twins may sustain cerebral damage that is in excess of that due to immaturity.?? PMID:11207227

Pharoah, P

2001-01-01

233

Ocular manifestations of Noonan syndrome in twin siblings: A case report of keratoconus with acute corneal hydrops  

PubMed Central

Ocular manifestations of Noonan syndrome (NS) in a set of healthy 20-year-old African-American fraternal twins are reported with emphasis on a rare finding of keratoconus with acute corneal hydrops in one twin. Both the twins had learning disabilities and attended a special needs school. Evaluation included visual acuity assessment, tonometry and external eye, slit lamp and dilated fundus examinations, topography with Pentacam and external photographs. The first case was more remarkable as keratoconus with acute corneal hydrops was observed. The patient presented with severe cloudy vision that had worsened over a span of 1 month. It improved significantly on follow-up. The second case included a unique constellation of ocular pathology that highlights the diversity of NS manifestations even amongst twins. Conservative treatment of keratoconus with acute corneal hydrops in a NS patient helped largely resolve the patient's condition. We report the diverse spectrum of ocular manifestations associated with this rare congenital disorder. PMID:25579364

Lee, Anna; Sakhalkar, Monali V

2014-01-01

234

Ocular manifestations of Noonan syndrome in twin siblings: A case report of keratoconus with acute corneal hydrops.  

PubMed

Ocular manifestations of Noonan syndrome (NS) in a set of healthy 20-year-old African-American fraternal twins are reported with emphasis on a rare finding of keratoconus with acute corneal hydrops in one twin. Both the twins had learning disabilities and attended a special needs school. Evaluation included visual acuity assessment, tonometry and external eye, slit lamp and dilated fundus examinations, topography with Pentacam and external photographs. The first case was more remarkable as keratoconus with acute corneal hydrops was observed. The patient presented with severe cloudy vision that had worsened over a span of 1 month. It improved significantly on follow-up. The second case included a unique constellation of ocular pathology that highlights the diversity of NS manifestations even amongst twins. Conservative treatment of keratoconus with acute corneal hydrops in a NS patient helped largely resolve the patient's condition. We report the diverse spectrum of ocular manifestations associated with this rare congenital disorder. PMID:25579364

Lee, Anna; Sakhalkar, Monali V

2014-12-01

235

151. Photocopy of drawing (taken from Twin Falls Canal Company ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

151. Photocopy of drawing (taken from Twin Falls Canal Company Surveyor's Transit Book #363, Page 20). SURVEY PRINT SHOWING POINT SPILLWAY AND FIELD NOTES, TWIN FALLS COUNTY NORTHWEST OF MURTAUGH, IDAHO. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

236

194. Photocopy of drawing, Twin Falls Canal Company, date unknown. ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

194. Photocopy of drawing, Twin Falls Canal Company, date unknown. PROFILE AND GATE PLAN, NORTH ISLAND CROSS SECTION OF DAM, TWIN FALLS COUNTY, MILNER, IDAHO; BLUEPRINT. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

237

195. Photocopy of drawing, Twin Falls Canal Company, date unknown. ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

195. Photocopy of drawing, Twin Falls Canal Company, date unknown. PLAN OF CONSTRUCTION AREA PLANT, TWIN FALLS COUNTY, MILNER, IDAHO; BLUEPRINT. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

238

183. Photocopy of map (Twin Falls Canal Company). TOPOGRAPHICAL MAP ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

183. Photocopy of map (Twin Falls Canal Company). TOPOGRAPHICAL MAP OF MILNER DAM SITE, TWIN FALLS COUNTY, MILNER, IDAHO; MAP, LEFT SIDE ONLY. CROSS REFERENCE: ID-15-192. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

239

193. Photocopy of Photograph, Twin Falls Canal Company, date unknown. ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

193. Photocopy of Photograph, Twin Falls Canal Company, date unknown. MILNER DAM PROFILE, TWIN FALLS COUNTY, MILNER, IDAHO; BLUEPRINT. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

240

187. Photocopy of drawing, Twin Falls Canal Company, date unknown. ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

187. Photocopy of drawing, Twin Falls Canal Company, date unknown. TOPOGRAPHICAL MAP OF MILNER DAM LOCATION, TWIN FALLS COUNTY, MILNER, IDAHO; BLUEPRINT MAP. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

241

185. Photocopy of drawing, Twin Falls Canal Company, date unknown. ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

185. Photocopy of drawing, Twin Falls Canal Company, date unknown. MILNER DAM CROSS SECTION PLAN, TWIN FALLS COUNTY, MILNER, IDAHO; BLUEPRINT. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

242

157. Photocopy of drawing (taken from Twin Falls Canal Company ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

157. Photocopy of drawing (taken from Twin Falls Canal Company Field Book #360, Page 75, entitled, 'Clay-Seam Cut-Off.' Cross-Reference: ID-15-153). MILNER DAM SURVEY, TWIN FALLS COUNTY, MILNER, IDAHO. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

243

155. Photocopy of transit book (taken from Twin Falls Canal ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

155. Photocopy of transit book (taken from Twin Falls Canal Company Surveyor's Transit Book #405T, Page 1, #46 Division One). STATEMENT RE: SURVEY ALIGNMENT 3/03, TWIN FALLS COUNTY, MILNER, IDAHO. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

244

186. Photocopy of drawing, Twin Falls Canal Company, date unknown. ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

186. Photocopy of drawing, Twin Falls Canal Company, date unknown. DRY CREEK RESERVOIR, CASSIA COUNTY (NOW TWIN FALLS COUNTY); MAP. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

245

158. Photocopy of transit book (taken from Twin Falls Canal ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

158. Photocopy of transit book (taken from Twin Falls Canal Company Transit Book #404T, Page 3, #46, Division One). START OF MAIN CANAL SURVEY, TWIN FALLS COUNTY, MILNER, IDAHO. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

246

189. Photocopy of drawing, Twin Falls Canal Company, date unknown. ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

189. Photocopy of drawing, Twin Falls Canal Company, date unknown. ROCK CREEK CROSSING, LOW LINE CANAL, TWIN FALLS COUNTY, SOUTH OF KIMBERLY, IDAHO; BLUEPRINT. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

247

191. Photocopy of drawing, Twin Falls Canal Company, date unknown. ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

191. Photocopy of drawing, Twin Falls Canal Company, date unknown. SPILLWAY GATES, MILNER DAM, TWIN FALLS COUNTY, MILNER, IDAHO; BLUEPRINT. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

248

177. Photocopy of Photograph, Twin Falls Canal Company, Bisbee Photo, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

177. Photocopy of Photograph, Twin Falls Canal Company, Bisbee Photo, September, 1912. Photographer unknown. COTTONWOOD FLUME, HIGH LINE CANAL, TWIN FALLS COUNTY, SOUTH OF KIMBERLY, IDAHO; SOUTH VIEW FROM UPPER SIDE. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

249

153. Photocopy of drawing (taken from Twin Falls Canal Company ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

153. Photocopy of drawing (taken from Twin Falls Canal Company Field Book #360, Page 74, entitled, 'Clay-Seam Cut-Off.' Cross-Reference: ID-15-157). MILNER DAM SURVEY, TWIN FALLS COUNTY, MILNER, IDAHO. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

250

190. Photocopy of drawing, Twin Falls Canal Company, date unknown. ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

190. Photocopy of drawing, Twin Falls Canal Company, date unknown. GENERAL PLAN OF MILNER DAM TUNNELS, TWIN FALLS COUNTY, MILNER, IDAHO; BLUEPRINT. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

251

152. Photocopy of drawing (taken from Twin Falls Canal Company ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

152. Photocopy of drawing (taken from Twin Falls Canal Company Surveyor's Transit Book #363, Page 1). 1912 CONDITION REPORT OF MILNER DAM AREA, TWIN FALLS COUNTY, MILNER, IDAHO. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

252

178. Photocopy of Photograph, Twin Falls Canal Company. C. R. ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

178. Photocopy of Photograph, Twin Falls Canal Company. C. R. Savage, Photographer, March, 1905. FIRST FULL WATER OVER MILNER DAM, TWIN FALLS COUNTY, MILNER, IDAHO; SOUTHWEST VIEW OF SPILLWAY GATES. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

253

154. Photocopy of transit book (taken from Twin Falls Canal ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

154. Photocopy of transit book (taken from Twin Falls Canal Company Surveyor's Transit Book #405T, Page 2, #46 Division One). STATEMENT OF SIGHT-SETTING FOR 1903 SURVEY TO ALIGN SOUTH SIDE CANAL, TWIN FALLS COUNTY, MILNER, IDAHO. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

254

181. Photocopy of Photograph, Twin Falls Canal Company. Photographer and ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

181. Photocopy of Photograph, Twin Falls Canal Company. Photographer and date unknown. POINT SPILL, TWIN FALLS COUNTY; SOUTH VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

255

192. Photocopy of drawing, Twin Falls Canal Company, date unknown. ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

192. Photocopy of drawing, Twin Falls Canal Company, date unknown. TOPOGRAPHICAL MAP (DAM DRAWN IN), MILNER SITE, TWIN FALLS COUNTY, MILNER, IDAHO; RIGHT SIDE OF MAP (LEFT ON ID-15-183). - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

256

182. Photocopy of Photograph, Twin Falls Canal Company. Photographer and ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

182. Photocopy of Photograph, Twin Falls Canal Company. Photographer and date unknown. MILNER DAM TUNNELS, TWIN FALLS COUNTY, MILNER, IDAHO; APPROACH TO TUNNELS. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

257

179. Photocopy of Photograph, Twin Falls Canal Company, Bisbee Photo, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

179. Photocopy of Photograph, Twin Falls Canal Company, Bisbee Photo, September, 1912. Photographer unknown. VIEW OF LOW LINE CANAL, TWIN FALLS COUNTY; VIEW OF LOW LINE CANAL IN PETE LINK'S FIELD. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

258

1. GENERAL VIEW OF THE LOWER END OF TWIN LAKES ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. GENERAL VIEW OF THE LOWER END OF TWIN LAKES SHOWING THE HISTORIC OUTLET WORKS AT THE EDGE OF THE WATER NEAR CENTER OF THE PHOTO WITH THE NEW TWIN LAKES DAM JUST BEHIND. VIEW LOOKING SOUTHEAST. - Twin Lakes Dam & Outlet Works, Beneath Twin Lakes Reservoir, T11S, R80W, S22, Twin Lakes, Lake County, CO

259

36. Photocopy of Photograph (original print located in the Twin ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

36. Photocopy of Photograph (original print located in the Twin Falls Library, Twin Falls, Idaho). Original Photograph, Bisbee Photo, William H. Eaton, Photographer, date unknown. COTTONWOOD FLUME SOUTH OF KIMBERLY, IDAHO. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

260

Clinical and echographic features of in utero cardiac dysfunction in the recipient twin in twin-twin transfusion syndrome  

Microsoft Academic Search

OBJECTIVE--Fetal twin-twin transfusion syndrome (TTTS) presenting in the second trimester has been associated with almost no perinatal survival until recently, when serial drainage of amniotic fluid has improved the prognosis to 70%-80%. Most recipient twins now survive but develop cardiac dysfunction. The study was undertaken to evaluate the abnormal echocardiographic features and clinical complications of cardiac disease in the recipient

N Zosmer; R Bajoria; E Weiner; M Rigby; J Vaughan; N M Fisk

1994-01-01

261

[Crohn disease in univitelline twins].  

PubMed

Authors report two homozygotic twins with Crohn's disease. Symptoms appeared at the ages of 11 and 13 and consisted mainly diarrhea accompanied by general signs of disease. Contrast X-Ray studies revealed in both ileo-cecal locations. In one of the patients there was an esophageal inflammation as well. In view of the obscure origin of Crohn's disease they consider interesting to report this familial observation in order to support genetic explanation. PMID:6686421

González, C; Alonso de la Miar, P; Baniela, N; Fernández de Diego, J I; Rivela, M; Gómez, J L

1983-10-01

262

A tale of two twins  

E-print Network

The thought experiment (called the clock paradox or the twin paradox)proposed by Langevin in 1911 of two observers, one staying on Earth and the other making a trip toward a star with a velocity near the light velocity is very well known for its surprising result. When the traveler comes back, he is younger that the stay on Earth. This astonishing situation deduced from the theory of Special relativity sparked a huge amount of articles, discussions and controversies such it remains a particular phenomenon probably unique in Physics. We propose to study it. First we looked for the simplest solutions when one can observe that the published solutions correspond in fact to two different versions of the experiment. It appears that the complete and simple solution of Moller is neglected for complicated methods with dubious validity. We propose to interpret this avalanche of works by the difficulty to accept the conclusions of the Special Relativity, in particular the difference in times indicated by two clocks, one immobile and the second moving and finally stopping. We also suggest that the name "twin paradox" is maybe related to some subconscious idea concerning conflict between twins as it can be found in the Bible and in several mythologies

Lucien Benguigui

2012-12-18

263

Psychiatric resilience: longitudinal twin study  

PubMed Central

Objective There is great variability in response to stressful life events (SLEs), with some individuals demonstrating substantial psychiatric symptoms while others remain largely asymptomatic. The source of this variability is poorly understood. The present study aimed to examine the genetic and environmental underpinning of resilience, defined as the difference between the twins’ total score on a broad measure of internalizing symptoms and their predicted score based on their cumulative exposure to SLEs. Method SLE exposure and internalizing symptoms were assessed at two time points in 7,500 adult twins. Using the residual between actual and predicted internalizing symptom total score, twin modeling was conducted for each wave separately, as well as longitudinally. Quantitative and qualitative sex effects were also tested. Results Resilience was found to have a mild to moderate genetic heritability at each individual wave (~31%). Additionally, qualitative sex effects were found. Incorporating error of measurement into the model increased the estimated heritability for the latent construct of resilience (~50%). Unconfounded by measurement error and occasion specific effects, environmental influences contributed roughly equally to determining the individual level of resilience. Conclusions Genetic factors influence the level of psychiatric resilience, and are largely stable over time. The genes that impact on resilience are not entirely the same in males and females, although the degree of heritability is equal across the sexes. Environmental influences can also have an enduring effect on resilience. The present findings of the genetic and environmental influences on adaptation to SLEs clarify the sources of individual variation to environmental stressors. PMID:24723629

Amstadter, Ananda B.; Myers, John M.; Kendler, Kenneth S.

2014-01-01

264

Twins Eye Study in Tasmania (TEST): Rationale and Methodology to Recruit and Examine Twins  

PubMed Central

Visual impairment is a leading cause for morbidity and poor quality of life in our community. Unravelling the mechanisms underpinning important blinding diseases could allow for preventative or curative steps to be implemented. Twin siblings provide a unique opportunity in biology to discover genes associated with numerous eye diseases and ocular biometry. Twins are particularly useful for quantitative trait analysis through genome-wide association and linkage studies. Although many studies involving twins rely on twin registries, we present our approach to the Twins Eye Study in Tasmania to provide insight into possible recruitment strategies, expected participation rates and potential examination strategies that can be considered by other researchers for similar studies. Five separate avenues for cohort recruitment were adopted: 1) piggy-backing existing studies where twins had been recruited; 2); utilising the national twin registry; 3) word of mouth and local media publicity; 4) directly approaching schools; and finally 5) collaborating with other research groups studying twins. PMID:19803772

Mackey, David A; MacKinnon, Jane R; Brown, Shayne A; Kearns, Lisa S; Ruddle, Jonathan B; Sanfilippo, Paul G; Sun, Cong; Hammond, Christopher J; Young, Terri L; Martin, Nicholas G; Hewitt, Alex W

2013-01-01

265

The TWINS Science Data System after the launch of TWINS 1  

NASA Astrophysics Data System (ADS)

The Two Wide-angle Imaging Neutral-atom Spectrometers (TWINS) 1 satellite is in orbit and science data are expected to commence in the near future. TWINS-1 comprises half of the TWINS stereoscopic neutral atom imaging system that will advance our knowledge of the Earth's ring current. To support the expected data return, we have developed a Science Data System (SDS) for the TWINS mission. The TWINS SDS is an IDL- and Java- driven data interface that operates primarily via a web browser, and has as its spine an SQL-queryable database. Through this interface, TWINS science data will be provided to the TWINS team, the space science community, and the public. In this paper we present the current and future capabilities of the TWINS SDS, as well as how the SDS fits into virtual observatory infrastructure.

Goldstein, J.; Valek, P.; Skoug, R.; Delapp, D.; Redfern, J.; Carruth, B.; McComas, D.

2007-05-01

266

Advanced characterization of twins using automated EBSD  

SciTech Connect

This poster describes resuns obtained using an automated, crystallographically-based technique for twin identification. The technique is based on the automated EBSD. The key features of the analysis are identification of potential twin boundaries by their misorientation character, identification of the distinct boundary planes among the symmetrically equiwlent candidates. and validation of these boundaries through comparison with the boundary and twin plane traces in the sample cross section. Results on the application of this technique to deformation twins in zirconium are analyzed for the effect of twin type and amount and sense of uniaxial deformation. The accumulation of strain tends to increase the misorientation deviation at least to the degree of the trace deviation compared with recrystalllzation twins in nickel.

Wright, S. I. (Stuart I.); Bingert, J. F. (John F.); Mason, T. A. (Thomas A.); Larsen, Ryan J.

2002-01-01

267

Multiple regression analysis of twin data  

Microsoft Academic Search

A multiple regression model for the analysis of twin data is described in which a cotwin's score is predicted from a proband's score and the coefficient of relationship (R=1.0 and 0.5 for identical and fraternal twin pairs, respectively). This model is especially appropriate for the analysis of data on twins in which one member of each pair has been selected

J. C. DeFries; David W. Fulker

1985-01-01

268

Australian Twin Registry: 30 years of progress.  

PubMed

The Australian Twin Registry (ATR) is a national volunteer resource of twin pairs and higher-order multiples willing to consider participating in health, medical, and scientific research. The vision of the ATR is 'to realize the full potential of research involving twins to improve the health and well-being of all Australians'. The ATR has been funded continuously by the National Health and Medical Council for more than 30 years. Its core functions entail the recruitment and retention of twin members, the maintenance of an up-to-date database containing members' contact details and baseline information, and the promotion and provision of open access to researchers from all institutes in Australia, and their collaborators, in a fair and equitable manner. The ATR is administered by The University of Melbourne, which acts as custodian. Since the late 1970s the ATR has enrolled more than 40,000 twin pairs of all zygosities and facilitated more than 500 studies that have produced at least 700 peer-reviewed publications from classical twin studies, co-twin control studies, within-pair comparisons, twin family studies, longitudinal twin studies, randomized controlled trials, and epigenetics studies, as well as studies of issues specific to twins. New initiatives include: a Health and Life Style Questionnaire; data collection, management, and archiving using a secure online software program (The Ark); and the International Network of Twin Registries. The ATR's expertise and 30 years of experience in providing services to national and international twin studies has made it an important resource for research across a broad range of disciplines. PMID:23200298

Hopper, John L; Foley, Debra L; White, Paul A; Pollaers, Vincent

2013-02-01

269

Genetic Regulation of Acquired Immune Responses to Antigens of Mycobacterium tuberculosis: a Study of Twins in West Africa  

Microsoft Academic Search

The role of genetic factors in clinical tuberculosis is increasingly recognized; how such factors regulate the immune response to Mycobacterium tuberculosis in healthy individuals is unclear. In this study of 255 adult twin pairs residing in The Gambia, West Africa, it is apparent that memory T-cell responses to secreted mycobac- terial antigens (85-kDa antigen complex, \\

ANNETTE JEPSON; AMANDA FOWLER; WINSTON BANYA; MAHAVIR SINGH; STEVE BENNETT; HILTON WHITTLE; ADRIAN V. S. HILL

2001-01-01

270

Endoscopic Laser Surgery versus Serial Amnioreduction for Severe Twin-to-Twin Transfusion Syndrome  

Microsoft Academic Search

background Monochorionic twin pregnancies complicated by severe twin-to-twin transfusion syn- drome at midgestation can be treated by either serial amnioreduction (removal of large volumes of amniotic fluid) or selective fetoscopic laser coagulation of the communicat- ing vessels on the chorionic plate. We conducted a randomized trial to compare the effi- cacy and safety of these two treatments. methods Pregnant women

Marie-Victoire Senat; Jan Deprest; Michel Boulvain; Alain Paupe; Norbert Winer; Yves Ville

2004-01-01

271

Twin Loss: Implications for Counselors Working with Surviving Twins.(practice & Theory)  

ERIC Educational Resources Information Center

Multiple births are becoming increasingly prevalent due to the use of fertility drugs and women choosing to wait until later life to conceive. With the growth in the twin population, little research has been done to investigate the effects on the grief process when 1 twin dies. Counselors must understand the unique experience of twins to formulate…

Withrow, Rebecca; Schwiebert, Valerie L.

2005-01-01

272

INCREASED TWINNING AND COW PRODUCTIVITY IN BEEF CATTLE SELECTED FOR OVULATION AND TWINNING RATE  

Technology Transfer Automated Retrieval System (TEKTRAN)

Since 1981, cattle have been selected for fraternal twin births using estimated breeding values for twinning calculated from repeated measurements of ovulation rate in all heifer progeny starting at about 12 months of age, from twinning rate in the selected females, and from progeny testing and sub...

273

Deformation-Twin-Induced Grain Boundary Failure  

SciTech Connect

This work presents a mechanism of deformation-twin-induced grain boundary failure, and demonstrates the mechanism using molecular dynamics simulations. Deformation twinning is observed as the dominant mechanism during tensile deformation of columnar nanocrystalline body-centered cubic Mo. As a twin approaches a grain boundary, local stress concentration develops due to the incompatible plastic deformations in the two neighboring grains. The magnitude of the stress concentration increases as the twin widens, leading to grain boundary cracking by nucleation and coalescence of microcracks/voids.

Yongfeng Zhang; Paul C. MIllett; Michael Tonks; Bulent Biner

2012-01-01

274

Atomistic deformation mechanisms in twinned copper nanospheres  

PubMed Central

In the present study, we perform molecular dynamic simulations to investigate the compression response and atomistic deformation mechanisms of twinned nanospheres. The relationship between load and compression depth is calculated for various twin spacing and loading directions. Then, the overall elastic properties and the underlying plastic deformation mechanisms are illuminated. Twin boundaries (TBs) act as obstacles to dislocation motion and lead to strengthening. As the loading direction varies, the plastic deformation transfers from dislocations intersecting with TBs, slipping parallel to TBs, and then to being restrained by TBs. The strengthening of TBs depends strongly on the twin spacing. PMID:25024693

2014-01-01

275

Asymmetry between Sister Cells in a Cancer Cell Line Revealed by Chemical Cytometry  

E-print Network

valuable in quantitative studies of cells with complex proliferation kinetics (e.g., stem cells). Asymmetry for embryogenesis and tissue regeneration.1-2 Asymmetric development of sister cells is governed by the differencesAsymmetry between Sister Cells in a Cancer Cell Line Revealed by Chemical Cytometry Kang Hu

Krylov, Sergey

276

Sister chromatid exchange test detection of toxin-induced damage in cultured fish  

E-print Network

Sister chromatid exchange test detection of toxin-induced damage in cultured fish J Lobillo JV Animals; Toulouse-Auzeville, 10-13 July 1990) sister chromatid exchange (SCE) / genotoxicity / fish the effects of these wastes on the autochthonous cultured and wild fish species of the Southern Atlantic off

Paris-Sud XI, Université de

277

Evolutionary Applications (in press, December 2008) Genomic Sister-Disorders of Neurodevelopment  

E-print Network

-Magenis syndrome, as well as the X-chromosomal conditions Klinefelter and Turner syndromes. These data suggest neurogenetic sister-disorders, including Williams syndrome, Velocardiofacial syndrome, and Smith of protein-coding genes, or selective sweeps, for three of the four sets of sister-syndromes analyzed

Crespi, Bernard J.

278

20 CFR 725.224 - Determination of relationship; parent, brother, or sister.  

Code of Federal Regulations, 2011 CFR

...will be considered to be the parent, brother, or sister of a miner if the courts of the State in which the miner...225.231) at the time of death would find, under the law...individual is the miner's parent, brother, or sister....

2011-04-01

279

20 CFR 725.224 - Determination of relationship; parent, brother, or sister.  

Code of Federal Regulations, 2013 CFR

...will be considered to be the parent, brother, or sister of a miner if the courts of the State in which the miner...225.231) at the time of death would find, under the law...individual is the miner's parent, brother, or sister....

2013-04-01

280

20 CFR 725.224 - Determination of relationship; parent, brother, or sister.  

Code of Federal Regulations, 2012 CFR

...will be considered to be the parent, brother, or sister of a miner if the courts of the State in which the miner...225.231) at the time of death would find, under the law...individual is the miner's parent, brother, or sister....

2012-04-01

281

20 CFR 725.224 - Determination of relationship; parent, brother, or sister.  

Code of Federal Regulations, 2010 CFR

...will be considered to be the parent, brother, or sister of a miner if the courts of the State in which the miner...225.231) at the time of death would find, under the law...individual is the miner's parent, brother, or sister....

2010-04-01

282

20 CFR 725.224 - Determination of relationship; parent, brother, or sister.  

...will be considered to be the parent, brother, or sister of a miner if the courts of the State in which the miner...225.231) at the time of death would find, under the law...individual is the miner's parent, brother, or sister....

2014-04-01

283

Twins 3D Face Recognition Challenge Vipin Vijayan  

E-print Network

known to the authors. Recently, there have been some twin studies in biomet rics research. Phillips et-twins compared to using twins for their iris biometric system. For their fingerprint biomet ric system

Kakadiaris, Ioannis

284

78 FR 28125 - Airworthiness Directives; Twin Commander Aircraft LLC Airplanes  

Federal Register 2010, 2011, 2012, 2013

...Airworthiness Directives; Twin Commander Aircraft LLC Airplanes AGENCY: Federal Aviation...directive (AD) for certain Twin Commander Aircraft LLC Models 690, 690A, and 690B airplanes...identified in this AD, contact Twin Commander Aircraft LLC; 1176 Telecom Drive,...

2013-05-14

285

Telomere sister chromatid exchange in telomerase deficient murine cells  

SciTech Connect

We have recently demonstrated that several types of genomic rearrangements (i.e., telomere sister chromatid exchange (T-SCE), genomic-SCE, or end-to-end fusions) were more often detected in long-term cultured murine telomerase deficient embryonic stem (ES) cells than in freshly prepared murine splenocytes, even through they possessed similar frequencies of critically short telomeres. The high rate of genomic rearrangements in telomerase deficient ES cells, when compared to murine splenocytes, may reflect the cultured cells' gained ability to protect chromosome ends with eroded telomeres allowing them to escape 'end crisis'. However, the possibility that ES cells were more permissive to genomic rearrangements than other cell types or that differences in the microenvironment or genetic background of the animals might consequentially determine the rate of T-SCEs or other genomic rearrangements at critically short telomeres could not be ruled out.

Wang, Yisong [ORNL; Giannone, Richard J [ORNL; Liu, Yie [ORNL

2005-01-01

286

Narcolepsy with cataplexy mimicry: the strange case of two sisters.  

PubMed

We report on two sisters, 17 and 12 years of age, with clinical features suggesting narcolepsy with cataplexy (NC): daytime sleepiness, spontaneous and emotionally triggered sudden falls to the ground, and overweight/obesity. MSLT showed borderline sleep latency, with 1 and 0 sleep onset REM periods. HLA typing disclosed the DQB1*0602 allele. Video-polygraphy of the spells ruled out NC diagnosis by demonstrating their easy elicitation by suggestion, with wake EEG, electromyographic persistence of muscle tone, and stable presence of tendon reflexes (i.e., pseudo-cataplexy), together with normal cerebrospinal hypocretin-1 levels. Our cases emphasize the need of a clear depiction of cataplexy pattern at the different ages, the usefulness of examining ictal neurophysiology, and collecting all available disease markers in ambiguous cases. PMID:23772196

Pizza, Fabio; Vandi, Stefano; Poli, Francesca; Moghadam, Keivan Kaveh; Franceschini, Christian; Bellucci, Claudia; Cipolli, Carlo; Ingravallo, Francesca; Natalini, Giuliana; Mignot, Emmanuel; Plazzi, Giuseppe

2013-01-01

287

Interview: Tatyana Lipovskaya, Sisters Sexual Assault Recovery Centre, Moscow, Russia.  

PubMed

The Sisters' Sexual Assault Recovery Center was established in Moscow, Russia, in 1993, to address the needs of victims of sexual violence. The Center's help-line received 4029 crisis calls in 1994-97. Most clients are seeking information about medical services or legal aid. Others call about employment, HIV/AIDS, alcoholism, and drug abuse. Services are available without regard to age, sex, occupation, or sexual orientation. Program funding has come entirely from Western foundations and organizations. Although Russia has not passed a law on domestic violence, the post-Communism government is reluctantly starting to acknowledge that rape and domestic violence are serious social problems. The Center runs an educational program for law enforcement officers to increase their sensitivity and create an environment of safety for women who report sexual violence. PMID:12294414

1998-11-01

288

11. Photographic copy of copy of Twin Lakes Outlet Works ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

11. Photographic copy of copy of Twin Lakes Outlet Works construction drawing dated January 15, 1951. Drawn by W.A. Doe for the Twin Lakes Reservoir and Canal Co. (copy in possession of Bureau of Reclamation, location of original unknown) 'AS CONSTRUCTED' PLANS OF 1949-1950, REHABILITATION OF TWIN LAKES RESERVOIR OUTLET WORKS, DETAILS OF UPSTREAM WING WALLS. - Twin Lakes Dam & Outlet Works, Beneath Twin Lakes Reservoir, T11S, R80W, S22, Twin Lakes, Lake County, CO

289

12. Photographic copy of copy of Twin Lakes Outlet Works ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

12. Photographic copy of copy of Twin Lakes Outlet Works construction drawing dated January 15, 1951. Drawn by W.A. Doe for the Twin Lakes Reservoir and Canal Co. (copy in possession of Bureau of Reclamation, location of original unknown) 'AS CONSTRUCTED' PLANS OF 1949-50, REHABILITATION OF TWIN LAKES RESERVOIR OUTLET WORKS, DETAILS OF DISCHARGE BASIN. - Twin Lakes Dam & Outlet Works, Beneath Twin Lakes Reservoir, T11S, R80W, S22, Twin Lakes, Lake County, CO

290

The geography and ecology of plant speciation: range overlap and niche divergence in sister species.  

PubMed

A goal of evolutionary biology is to understand the roles of geography and ecology in speciation. The recent shared ancestry of sister species can leave a major imprint on their geographical and ecological attributes, possibly revealing processes involved in speciation. We examined how ecological similarity, range overlap and range asymmetry are related to time since divergence of 71 sister species pairs in the California Floristic Province (CFP). We found that plants exhibit strikingly different age-range correlation patterns from those found for animals; the latter broadly support allopatric speciation as the primary mode of speciation. By contrast, plant sisters in the CFP were sympatric in 80% of cases and range sizes of sisters differed by a mean of 10-fold. Range overlap and range asymmetry were greatest in younger sisters. These results suggest that speciation mechanisms broadly grouped under 'budding' speciation, in which a larger ranged progenitor gives rise to a smaller ranged derivative species, are probably common. The ecological and reproductive similarity of sisters was significantly greater than that of sister-non-sister congeners for every trait assessed. However, shifts in at least one trait were present in 93% of the sister pairs; habitat and soil shifts were especially common. Ecological divergence did not increase with range overlap contrary to expectations under character displacement in sympatry. Our results suggest that vicariant speciation is more ubiquitous in animals than plants, perhaps owing to the sensitivity of plants to fine-scale environmental heterogeneity. Despite high levels of range overlap, ecological shifts in the process of budding speciation may result in low rates of fine-scale spatial co-occurrence. These results have implications for ecological studies of trait evolution and community assembly; despite high levels of sympatry, sister taxa and potentially other close relatives, may be missing from local communities. PMID:24452025

Anacker, Brian L; Strauss, Sharon Y

2014-03-01

291

Sisters Together: Move More, Eat Better Energize Yourself  

E-print Network

and eat better?............................................ 2 How much physical activity do I need? ................................. 3 How can I handle barriers to becoming more physically active know? Eating healthy foods and staying physically active can help you keep up with the demands of your

Rau, Don C.

292

Twin-Foucault imaging method  

NASA Astrophysics Data System (ADS)

A method of Lorentz electron microscopy, which enables observation two Foucault images simultaneously by using an electron biprism instead of an objective aperture, was developed. The electron biprism is installed between two electron beams deflected by 180° magnetic domains. Potential applied to the biprism deflects the two electron beams further, and two Foucault images with reversed contrast are then obtained in one visual field. The twin Foucault images are able to extract the magnetic domain structures and to reconstruct an ordinary electron micrograph. The developed Foucault method was demonstrated with a 180° domain structure of manganite La0.825Sr0.175MnO3.

Harada, Ken

2012-02-01

293

Attractiveness Differences Between Twins Predicts Evaluations of Self and Co-Twin  

PubMed Central

One of the most consistent findings in psychology shows that people prefer and make positive attributions about attractive compared with unattractive people. The goal of the current study was to determine the power of attractiveness effects by testing whether these social judgments are made where attractiveness differences are smallest: between twins. Differences in facial attractiveness predicted twins’ evaluations of self and their co-twin (n = 158; 54 male). In twin pairs, the more attractive twin judged their less attractive sibling as less physically attractive, athletic, socially competent, and emotionally stable. The less attractive twin did the reverse. Given that even negligible differences in facial attractiveness predicted self and co-twin attitudes, these results provide the strongest test yet of appearance-based stereotypes. PMID:23467329

Principe, Connor P.; Rosen, Lisa H.; Taylor-Partridge, Teresa; Langlois, Judith H.

2012-01-01

294

The power of the classical twin study  

Microsoft Academic Search

A method based on the non-central chi-square distribution is developed for the calculation of sample sizes required to reject, with given probability, models of variation when they are “ wrong ”. The method is illustrated with reference to simple alternative models of variation in MZ and DZ twins reared together. Simulation of twin experiments finds the empirical power in good

N. G. MARTIN; L. J. EAVES; M. J. KEARSEY; P. DAVIESt

1978-01-01

295

[Hungarian twin studies: results of four decades].  

PubMed

Twin studies play a role in examining the contribution of genetic variations and environmental factors responsible for the determination of phenotypic variables and of genetic linkage between genotypes. Hungarian twin studies, supported by three twin registries (among them two twin-database), date back to 1970s. Studies mainly focused on various congenital abnormalities, the effect of contraceptive pills and folic acid on the frequency of twin pregnancies, as well as psychosexual and alcohol consumptional behaviors. Monogenic Mendelian inheritance of lactose (mal)absorption was demonstrated for the first time. Hungarian Twin Registry was founded in 2007, which contributed to the current understanding on the background of several disorders, e.g. metabolic syndrome and atherosclerosis. As part of an international twin study, among others, arterial stiffness, central blood pressure, carotid intima/media thickness, venous biomechanics, body composition, lung function and smoking characteristics were also assessed. Absence of genetic background in non-alcoholic fatty liver disease and high inheritance of carotid plaque characteristics were demonstrated for the first time. The review also aims to summarize future plans of the Hungarian Twin Registry. PMID:24077161

Tárnoki, Ádám Domonkos; Tárnoki, Dávid László; Horváth, Tamás; Métneki, Júlia; Littvay, Levente

2013-10-01

296

Niemann-Pick Type C Disease in Two Affected Sisters: Ocular Motor Recordings and BrainStem Neuropathology  

Microsoft Academic Search

Two sisters with Niemann-Pick disease type C were examined: the brain in one sister, who had died, was examined, and eye movements in the other, surviving sister were recorded. Ocular motor recordings showed marked slowing of vertical saccades with relative sparing of horizontal saccades, pursuit, and the vestibulo-ocular reflex. Neuropathological findings included glial fibrillary lesions in the area of the

David Solomon; A. Charles Winkelman; David S. Zee; Lawrence Gray; Jean Büttner-Ennever

2005-01-01

297

Highlights from the 15th International Congress of Twin Studies/Twin Research: Differentiating MZ Co-twins Via SNPs; Mistaken Infant Twin-Singleton Hospital Registration; Narcolepsy With Cataplexy; Hearing Loss and Language Learning/Media Mentions: Broadway Musical Recalls Conjoined Hilton Twins; High Fashion Pair; Twins Turn 102; Insights From a Conjoined Twin Survivor.  

PubMed

Highlights from the 15th International Congress of Twin Studies are presented. The congress was held November 16-19, 2014 in Budapest, Hungary. This report is followed by summaries of research addressing the differentiation of MZ co-twins by single nucleotide polymorphisms (SNPs), an unusual error in infant twin-singleton hospital registration, twins with childhood-onset narcolepsy with cataplexy, and the parenting effects of hearing loss in one co-twin. Media interest in twins covers a new Broadway musical based on the conjoined twins Violet and Daisy Hilton, male twins becoming famous in fashion, twins who turned 102 and unique insights from a conjoined twin survivor. This article is dedicated to the memory of Elizabeth (Liz) Hamel, DZA twin who met her co-twin for the first time at age seventy-eight years. Liz and her co-twin, Ann Hunt, are listed in the 2015 Guinness Book of Records as the longest separated twins in the world. PMID:25662422

Segal, Nancy L

2015-02-01

298

Niobium and tantalum: indispensable twins  

USGS Publications Warehouse

Niobium and tantalum are transition metals almost always paired together in nature. These “twins” are difficult to separate because of their shared physical and chemical properties. In 1801, English chemist Charles Hatchett uncovered an unknown element in a mineral sample of columbite; John Winthrop found the sample in a Massachusetts mine and sent it to the British Museum in London in 1734. The name columbium, which Hatchet named the new element, came from the poetic name for North America—Columbia—and was used interchangeably for niobium until 1949, when the name niobium became official. Swedish scientist Anders Ekberg discovered tantalum in 1802, but it was confused with niobium, because of their twinned properties, until 1864, when it was recognized as a separate element. Niobium is a lustrous, gray, ductile metal with a high melting point, relatively low density, and superconductor properties. Tantalum is a dark blue-gray, dense, ductile, very hard, and easily fabricated metal. It is highly conductive to heat and electricity and renowned for its resistance to acidic corrosion. These special properties determine their primary uses and make niobium and tantalum indispensable.

Schulz, Klaus; Papp, John

2014-01-01

299

Pregnancy and Healthy Weight  

MedlinePLUS

... Media Resources Selected Profiles & Interviews Multimedia Pregnancy & Healthy Weight Skip sharing on social media links Share this: ... Content New research shows that maintaining a healthy weight before and during pregnancy can reduce the likelihood ...

300

NOTE: Modelling the influence of amnionicity on the severity of twin twin transfusion syndrome in monochorionic twin pregnancies  

NASA Astrophysics Data System (ADS)

Clinical treatment for diamniotic monochorionic twin twin transfusion syndrome (TTTS) may include conversion of diamniotic pregnancies to a monoamniotic monochorionic state by disrupting the amnion septum. We sought to test the underlying hypothesis, i.e. that a monoamniotic state reduces the severity of TTTS. With use of our previously developed mathematical model of two equal fetoplacental circulatory units connected by various sizes and types of placental anastomoses, we compared the haemodynamic and amniotic fluid dynamics of monoamniotic and diamniotic twins that develop TTTS. We used three anastomotic patterns that produce severe, moderate or mild forms of TTTS, respectively, in our diamniotic monochorionic twin model. Monoamnionicity was modelled by adding the two amniotic fluid volumes and using the volume-averaged amniotic fluid osmolality. The results were as follows: for severe TTTS, small differences develop between diamniotic and monoamniotic donor twins in fetal urine production, swallowed volume, blood volume, blood pressures, net fetofetal transfusion, and blood and amniotic fluid osmolality. However, the circulatory imbalance between the monoamniotic twins deteriorates similar to that of diamniotic twins. The pathophysiological differences tend to disappear for milder TTTS. In conclusion, our model suggests that the uncommon finding of TTTS in monoamniotic twins is not due to the presence of a single amniotic sac. Rather, clinically significant differences in anastomotic patterns and the delayed or lack of identification of manifestations in monoamniotic twins account for the reduced rate of TTTS diagnosis. Based on these results we expect the clinical disruption of the amnion septum in diamniotic monochorionic TTTS pregnancies to have only minimal benefits.

van den Wijngaard, Jeroen P. H. M.; Umur, Asli; Ross, Michael G.; van Gemert, Martin J. C.

2004-03-01

301

Healthy Diet Weight Control  

E-print Network

· Healthy Diet · Weight Control Diet and Obesity #12;Maintaining a Healthy Diet, hypertension ­ Diabetes ­ Cancer · Low SES #12;Why Maintain a Healthy Diet? · Dietary factors contribute death, salt and HTN ­ Estimates of degree to which diet contributes to cancer range between 30

Meagher, Mary

302

Bellagio Report on Healthy Agriculture, Healthy Nutrition, Healthy People.  

PubMed

The Bellagio Report on Healthy Agriculture, Healthy Nutrition, Healthy People is the result of the meeting held at the Rockefeller Foundation Bellagio Center in Lake Como, Italy 30 October-1 November, 2012. The meeting was science-based but policy-oriented. The role and amount of healthy and unhealthy fats, with attention to the relative content of omega-3 and omega-6 fatty acids, sugar, and particularly fructose in foods that may underlie the epidemics of non-communicable diseases (NCDs) worldwide were extensively discussed. The report concludes that sugar consumption, especially in the form of high energy fructose in soft drinks, poses a major and insidious health threat, especially in children, and most diets, although with regional differences, are deficient in omega-3 fatty acids and too high in omega-6 fatty acids. Gene-nutrient interactions in growth and development and in disease prevention are fundamental to health, therefore regional Centers on Genetics, Nutrition and Fitness for Health should be established worldwide. Heads of state and government must elevate, as a matter of urgency, nutrition as a national priority, that access to a healthy diet should be considered a human right and that the lead responsibility for nutrition should be placed in Ministries of Health rather than agriculture so that the health requirements drive agricultural priorities, not vice versa. Nutritional security should be given the same priority as food security. PMID:23698143

Simopoulos, Artemis P; Bourne, Peter G; Faergeman, Ole

2013-03-01

303

Bellagio report on healthy agriculture, healthy nutrition, healthy people.  

PubMed

The Bellagio Report on Healthy Agriculture, Healthy Nutrition, Healthy People is the result of the meeting held at the Rockefeller Foundation Bellagio Center in Lake Como, Italy, 29 October-2 November 2012. The meeting was science-based but policy-oriented. The role and amount of healthy and unhealthy fats, with attention to the relative content of omega-3 and omega-6 fatty acids, sugar, and particularly fructose in foods that may underlie the epidemics of non-communicable diseases (NCD's) worldwide were extensively discussed. The report concludes that sugar consumption, especially in the form of high energy fructose in soft drinks, poses a major and insidious health threat, especially in children, and most diets, although with regional differences, are deficient in omega-3 fatty acids and too high in omega-6 fatty acids. Gene-nutrient interactions in growth and development and in disease prevention are fundamental to health, therefore regional Centers on Genetics, Nutrition and Fitness for Health should be established worldwide. Heads of state and government must elevate, as a matter of urgency, Nutrition as a national priority, that access to a healthy diet should be considered a human right and that the lead responsibility for Nutrition should be placed in Ministries of Health rather than agriculture so that the health requirements drive agricultural priorities, not vice versa. Nutritional security should be given the same priority as food security. PMID:23385371

Simopoulos, Artemis P; Bourne, Peter G; Faergeman, Ole

2013-02-01

304

[Bellagio Report on Healthy Agriculture, Healthy Nutrition, Healthy People].  

PubMed

The Bellagio Report on Healthy Agriculture, Healthy Nutrition, Healthy People is the result of the meeting held at the Rockefeller Foundation Bellagio Center in Lake Como, Italy, 29 October-2 November 2012. The meeting was science-based but policy-oriented. The role and amount of healthy and unhealthy fats, with attention to the relative content of omega-3 and omega-6 fatty acids, sugar, and particularly fructose in foods that may underlie the epidemics of non-communicable diseases (NCD's) worldwide were extensively discussed. The report concludes that sugar consumption, especially in the form of high energy fructose in soft drinks, poses a major and insidious health threat, especially in children, and most diets, although with regional differences, are deficient in omega-3 fatty acids and too high in omega-6 fatty acids. Gene-nutrient interactions in growth and development and in disease prevention are fundamental to health, therefore regional Centers on Genetics, Nutrition and Fitness for Health should be established worldwide. Heads of state and government must elevate, as a matter of urgency, Nutrition as a national priority, that access to a healthy diet should be considered a human right and that the lead responsibility for Nutrition should be placed in Ministries of Health rather than agriculture so that the health requirements drive agricultural priorities, not vice versa. Nutritional security should be given the same priority as food security. PMID:24506349

Simopoulos, Artemis P; Bourne, Peter G; Faergeman, Ole

2013-01-01

305

Bellagio Report on Healthy Agriculture, Healthy Nutrition, Healthy People  

PubMed Central

The Bellagio Report on Healthy Agriculture, Healthy Nutrition, Healthy People is the result of the meeting held at the Rockefeller Foundation Bellagio Center in Lake Como, Italy, 29 October–2 November 2012. The meeting was science-based but policy-oriented. The role and amount of healthy and unhealthy fats, with attention to the relative content of omega-3 and omega-6 fatty acids, sugar, and particularly fructose in foods that may underlie the epidemics of non-communicable diseases (NCD’s) worldwide were extensively discussed. The report concludes that sugar consumption, especially in the form of high energy fructose in soft drinks, poses a major and insidious health threat, especially in children, and most diets, although with regional differences, are deficient in omega-3 fatty acids and too high in omega-6 fatty acids. Gene-nutrient interactions in growth and development and in disease prevention are fundamental to health, therefore regional Centers on Genetics, Nutrition and Fitness for Health should be established worldwide. Heads of state and government must elevate, as a matter of urgency, Nutrition as a national priority, that access to a healthy diet should be considered a human right and that the lead responsibility for Nutrition should be placed in Ministries of Health rather than agriculture so that the health requirements drive agricultural priorities, not vice versa. Nutritional security should be given the same priority as food security. PMID:23385371

Simopoulos, Artemis P.; Bourne, Peter G.; Faergeman, Ole

2013-01-01

306

Twinning tools in PLATON Detection and Absorption Correction  

E-print Network

Twinning tools in PLATON Detection and Absorption Correction Martin Lutz, Bijvoet Center, The Netherlands. #12;Merohedral Twins · The twin element belongs to the holohedry of the lattice, but not to the point group of the crystal. · The reciprocal lattices of all twin domains superimpose exactly

Meagher, Mary

307

122. MCMULLEN CREEK, TWIN FALLS COUNTY, SOUTH OF KIMBERLY, IDAHO; ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

122. MCMULLEN CREEK, TWIN FALLS COUNTY, SOUTH OF KIMBERLY, IDAHO; INLET SIDE OF THE CREEK, ENTRANCE INTO THE HIGH LINE CANAL, SOUTH VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

308

131. FORKS DIVERSION, HIGH LINE AND LOW LINE CANALS, TWIN ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

131. FORKS DIVERSION, HIGH LINE AND LOW LINE CANALS, TWIN FALLS COUNTY, SOUTH OF HANSEN, IDAHO; INLET SIDE OF LOW LINE CANAL, WEST VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

309

25. TWIN FALLS MAIN CANAL HEADWORKS FROM UPSTREAM LOOKING TOWARD ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

25. TWIN FALLS MAIN CANAL HEADWORKS FROM UPSTREAM LOOKING TOWARD THE WEST (DAM-TENDER RICHARD CARL ADJUSTING THE GATES TO ALLOW 3400 CFS THROUGH). - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

310

130. FORKS DIVERSION, HIGH LINE AND LOW LINE CANALS, TWIN ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

130. FORKS DIVERSION, HIGH LINE AND LOW LINE CANALS, TWIN FALLS COUNTY, SOUTH OF HANSEN, IDAHO; OUTLET SIDE OF THE HIGH LINE GATES, NORTH VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

311

120. COTTONWOOD CUT AREA, TWIN FALLS COUNTY, SOUTH OF KIMBERLY, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

120. COTTONWOOD CUT AREA, TWIN FALLS COUNTY, SOUTH OF KIMBERLY, IDAHO; OVERALL VIEW OF THE COTTONWOOD CREEK DRAW, SOUTH VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

312

117. COTTONWOOD CREEK SPILL, TWIN FALLS COUNTY, SOUTH OF KIMBERLY, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

117. COTTONWOOD CREEK SPILL, TWIN FALLS COUNTY, SOUTH OF KIMBERLY, IDAHO; CLOSE-UP OF OUTLET SIDE OF SPILL, SOUTH VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

313

Twin relationships in Parsimonious Games: some results Flavio Pressaccoa  

E-print Network

Twin relationships in Parsimonious Games: some results Flavio Pressaccoa , Giacomo Plazzottab, Isbell introduced a twin relationship based on transposition properties of the incidence matrices upon of some results on twin games presented in this paper. In detail we show that a) twin games have the same

Boyer, Edmond

314

119. COTTONWOOD CREEK SIPHON, TWIN FALLS COUNTY, SOUTH OF KIMBERLY, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

119. COTTONWOOD CREEK SIPHON, TWIN FALLS COUNTY, SOUTH OF KIMBERLY, IDAHO; INLET SIDE OF COTTONWOOD CREEK, SOUTH VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

315

Twin Estimates for Slopes Humberto Mu~noz  

E-print Network

Twin Estimates for Slopes by Humberto Mu~noz R. Baker Kearfott, rbk@louisiana.edu Department author's Ph.D. dissertation Interval Slopes and Twin Slope Arithmetic in Nonsmooth Optimization, University of Louisiana at Lafayette, 2001. Twin Estimates for Slopes May 25, VC02­1 #12;What is Twin

Kearfott, R. Baker

316

129. COTTONWOOD CREEK SIPHON, TWIN FALLS COUNTY, SOUTH OF KIMBERLY, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

129. COTTONWOOD CREEK SIPHON, TWIN FALLS COUNTY, SOUTH OF KIMBERLY, IDAHO; OUTLET SIDE OF SIPHON UNDER CANAL. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

317

28. VIEW FROM IMMEDIATELY DOWNSTREAM OF TWIN FALLS MAIN CANAL ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

28. VIEW FROM IMMEDIATELY DOWNSTREAM OF TWIN FALLS MAIN CANAL HEADWORKS WITH CANAL BRIDGE IN DISTANCE. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

318

8. BRIDGEWORK PLANKING FROM EAST SIDE WITH TWIN FALLS MAIN ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. BRIDGEWORK PLANKING FROM EAST SIDE WITH TWIN FALLS MAIN CANAL HEADWORKS IN DISTANCE; LOOKING WEST. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

319

126. COTTONWOOD CREEK SIPHON, TWIN FALLS COUNTY, SOUTH OF KIMBERLY, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

126. COTTONWOOD CREEK SIPHON, TWIN FALLS COUNTY, SOUTH OF KIMBERLY, IDAHO; CLOSE-UP OF OUTLET SIDE OF SIPHON, SOUTH VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

320

Microbial communities and the structure-function twins  

E-print Network

Microbial communities and the structure-function twins Stefanie Widder Division for Computational and the structure-function twins. #12;Stefanie Widder Microbial communities and the structure-function twins. Co? #12;Stefanie Widder Microbial communities and the structure-function twins. Motivation #12;Stefanie

321

124. MCMULLEN CREEK HIGH LINE CANAL, TWIN FALLS COUNTY, SOUTH ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

124. MCMULLEN CREEK HIGH LINE CANAL, TWIN FALLS COUNTY, SOUTH OF KIMBERLY, IDAHO; OVERALL SOUTH VIEW OF DRAW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

322

TWIN BUILDING LATTICES DO NOT HAVE ASYMPTOTIC CUT-POINTS  

E-print Network

TWIN BUILDING LATTICES DO NOT HAVE ASYMPTOTIC CUT-POINTS PIERRE-EMMANUEL CAPRACE*, FRANĂ?OIS DAHMANI**, AND VINCENT GUIRARDEL** Abstract. We show that twin building lattices have linear divergence, which implies of asymptotic cones of twin building lattices. Theorem 1. The asymptotic cones of a twin building lattice do

Caprace, Pierre-Emmanuel

323

118. COTTONWOOD CREEK SPILL, TWIN FALLS COUNTY, SOUTH OF KIMBERLY, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

118. COTTONWOOD CREEK SPILL, TWIN FALLS COUNTY, SOUTH OF KIMBERLY, IDAHO; WEST VIEW OF GATES ON HIGH LINE CANAL. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

324

123. MCMULLEN CREEK, HIGH LINE CANAL, TWIN FALLS COUNTY, SOUTH ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

123. MCMULLEN CREEK, HIGH LINE CANAL, TWIN FALLS COUNTY, SOUTH OF KIMBERLY, IDAHO; SOUTH VIEW OF THE CREEK EMPTYING INTO THE HIGH LINE CANAL. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

325

121. MCMULLEN CREEK DRAW, TWIN FALLS COUNTY, SOUTH OF KIMBERLY, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

121. MCMULLEN CREEK DRAW, TWIN FALLS COUNTY, SOUTH OF KIMBERLY, IDAHO; OUTLET SIDE OF CREEK, SOUTH VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

326

111. ROCK CREEK SIPHON LOW LINE CANAL, TWIN FALLS COUNTY, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

111. ROCK CREEK SIPHON LOW LINE CANAL, TWIN FALLS COUNTY, SOUTH OF KIMBERLY IDAHO; OVERALL VIEW OF SIPHON, EAST VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

327

112. ROCK CREEK SIPHON LOW LINE CANAL, TWIN FALLS COUNTY, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

112. ROCK CREEK SIPHON LOW LINE CANAL, TWIN FALLS COUNTY, SOUTH OF KIMBERLY IDAHO; OUTLET SIDE, EAST VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

328

113. ROCK CREEK SIPHON LOW LINE CANAL, TWIN FALLS COUNTY, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

113. ROCK CREEK SIPHON LOW LINE CANAL, TWIN FALLS COUNTY, SOUTH OF KIMBERLY IDAHO; CLOSE-UP OF INLET SIDE OF SIPHON, NORTHWEST VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

329

96. CEDAR DRAW SPILL, LOW LINE CANAL, TWIN FALLS COUNTY ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

96. CEDAR DRAW SPILL, LOW LINE CANAL, TWIN FALLS COUNTY SOUTH OF FILER, IDAHO; OUTLET SIDE OF CEDAR DRAW, WEST VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

330

91. CEDAR DRAW SPILL, HIGH LINE CANAL, TWIN FALLS COUNTY, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

91. CEDAR DRAW SPILL, HIGH LINE CANAL, TWIN FALLS COUNTY, SOUTH OF FILER, IDAHO; NORTHEAST VIEW OF CANAL AND GATES. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

331

88. CEDAR DRAW SPILL, HIGH LINE CANAL, TWIN FALLS COUNTY, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

88. CEDAR DRAW SPILL, HIGH LINE CANAL, TWIN FALLS COUNTY, SOUTH OF FILER, IDAHO; WEST VIEW OF CANAL AND GATES. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

332

93. ROCK CREEK SIPHON, LOW LINE CANAL, TWIN FALLS COUNTY ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

93. ROCK CREEK SIPHON, LOW LINE CANAL, TWIN FALLS COUNTY SOUTH OF KIMBERLY, IDAHO; OVERALL NORTHEAST VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

333

102. MURTAUGH LAKE HEADGATES, TWIN FALLS COUNTY, SOUTH OF MURTAUGH, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

102. MURTAUGH LAKE HEADGATES, TWIN FALLS COUNTY, SOUTH OF MURTAUGH, IDAHO; LAKE SIDE OF HEADGATES, NORTHWEST VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

334

103. DRY CREEK SPILL, TWIN FALLS COUNTY, SOUTH OF MURTAUGH, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

103. DRY CREEK SPILL, TWIN FALLS COUNTY, SOUTH OF MURTAUGH, IDAHO; INLET SIDE TO DRY CREEK, SOUTH VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

335

106. DRY CREEK SPILL, MURTAUGH LAKE, TWIN FALLS COUNTY, SOUTH ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

106. DRY CREEK SPILL, MURTAUGH LAKE, TWIN FALLS COUNTY, SOUTH OF MURTAUGH, IDAHO; CLOSE-UP OF GATES, NORTHWEST VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

336

90. CEDAR DRAW SPILL, HIGH LINE CANAL, TWIN FALLS COUNTY, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

90. CEDAR DRAW SPILL, HIGH LINE CANAL, TWIN FALLS COUNTY, SOUTH OF FILER, IDAHO; CLOSE-UP OF GATES. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

337

104. DRY CREEK OUTLET (SPILL), TWIN FALLS COUNTY, SOUTH OF ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

104. DRY CREEK OUTLET (SPILL), TWIN FALLS COUNTY, SOUTH OF MURTAUGH, IDAHO; OUTLET FOR MURTAUGH LAKE, SOUTHEAST VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

338

110. ROCK CREEK SIPHON, LOW LINE CANAL, TWIN FALLS COUNTY, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

110. ROCK CREEK SIPHON, LOW LINE CANAL, TWIN FALLS COUNTY, SOUTH OF KIMBERLY, IDAHO; INLET SIDE WEST VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

339

95. CEDAR DRAW SPILL, LOW LINE CANAL, TWIN FALLS COUNTY ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

95. CEDAR DRAW SPILL, LOW LINE CANAL, TWIN FALLS COUNTY SOUTH OF FILER, IDAHO; OVERALL VIEW LOOKING EAST. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

340

115. ROCK CREEK SIPHON LOW LINE CANAL, TWIN FALLS COUNTY, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

115. ROCK CREEK SIPHON LOW LINE CANAL, TWIN FALLS COUNTY, SOUTH OF KIMBERLY IDAHO; WEST VIEW OF SIPHON CROSSING ROCK CREEK. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

341

116. ROCK CREEK SIPHON LOW LINE CANAL, TWIN FALLS COUNTY, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

116. ROCK CREEK SIPHON LOW LINE CANAL, TWIN FALLS COUNTY, SOUTH OF KIMBERLY IDAHO; CLOSE-UP OF OUTLET, DIVERSION SPILL IN BACKGROUND, WEST VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

342

92. CEDAR DRAW SPILL, HIGH LINE CANAL, TWIN FALLS COUNTY ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

92. CEDAR DRAW SPILL, HIGH LINE CANAL, TWIN FALLS COUNTY SOUTH OF FILER, IDAHO; CLOSE-UP OF OUTLET SIDE OF GATES, SOUTH VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

343

105. MURTAUGH LAKE, TWIN FALLS COUNTY, SOUTH OF MURTAUGH, IDAHO; ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

105. MURTAUGH LAKE, TWIN FALLS COUNTY, SOUTH OF MURTAUGH, IDAHO; NORTHWEST VIEW OF LAKE AND HEADGATES. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

344

94. CEDAR DRAW SPILL, LOW LINE CANAL, TWIN FALLS COUNTY ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

94. CEDAR DRAW SPILL, LOW LINE CANAL, TWIN FALLS COUNTY SOUTH OF FILER, IDAHO; CLOSE-UP OF GATES FROM THE CANAL SIDE. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

345

109. CEDAR DRAW SPILL, LOW LINE CANAL, TWIN FALLS COUNTY, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

109. CEDAR DRAW SPILL, LOW LINE CANAL, TWIN FALLS COUNTY, SOUTH OF FILER, IDAHO; OVERALL VIEW LOOKING WEST. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

346

114. ROCK CREEK SIPHON LOW LINE CANAL, TWIN FALLS COUNTY, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

114. ROCK CREEK SIPHON LOW LINE CANAL, TWIN FALLS COUNTY, SOUTH OF KIMBERLY IDAHO; OVERALL VIEW, WEST OF INLET SIDE. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

347

101. DRY CREEK SPILL, MURTAUGH LAKE, TWIN FALLS COUNTY, SOUTH ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

101. DRY CREEK SPILL, MURTAUGH LAKE, TWIN FALLS COUNTY, SOUTH OF MURTAUGH, IDAHO; NORTHEAST VIEW OF DRY CREEK OUTLET. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

348

89. CEDAR DRAW SPILL, HIGH LINE CANAL, TWIN FALLS COUNTY, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

89. CEDAR DRAW SPILL, HIGH LINE CANAL, TWIN FALLS COUNTY, SOUTH OF FILER, IDAHO; OUTLET SIDE OF CANAL, SOUTHWEST VIEW. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

349

132. FORKS DIVERSION, HIGH LINE AND LOW LINE CANALS, TWIN ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

132. FORKS DIVERSION, HIGH LINE AND LOW LINE CANALS, TWIN FALLS COUNTY, SOUTH OF HANSEN, IDAHO; POWER GATES FOR HYDRO-ELECTRIC. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

350

197. Photocopy of drawing, Twin Falls, Canal Company, date unknown. ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

197. Photocopy of drawing, Twin Falls, Canal Company, date unknown. GATE STEMS AND LIFTING DEVICES, NO COUNTY; BLUEPRINT SKETCHES. - Milner Dam & Main Canal: Twin Falls Canal Company, On Snake River, 11 miles West of city of Burley, Idaho, Twin Falls, Twin Falls County, ID

351

Twin and Triplet Drugs in Opioid Research  

NASA Astrophysics Data System (ADS)

Twin and triplet drugs are defined as compounds that contain respectively two and three pharmacophore components exerting pharmacological effects in a molecule. The twin drug bearing the same pharmacophores is a "symmetrical twin drug", whereas that possessing different pharmacophores is a "nonsymmetrical twin drug." In general, the symmetrical twin drug is expected to produce more potent and/or selective pharmacological effects, whereas the nonsymmetrical twin drug is anticipated to show both pharmacological activities stemming from the individual pharmacophores (dual action). On the other hand, nonsymmetrical triplet drugs, which have two of the same pharmacophores and one different moiety, are expected to elicit both increased pharmacological action and dual action. The two identical portions could bind the same receptor sites simultaneously while the third portion could bind a different receptor site or enzyme. This review will mainly focus on the twin and triplet drugs with an evaluation of their in vivo pharmacological effects, and will also include a description of their pharmacology and synthesis.

Fujii, Hideaki

352

Chloroplast Phylogenomics Indicates that Ginkgo biloba Is Sister to Cycads  

PubMed Central

Molecular phylogenetic studies have not yet reached a consensus on the placement of Ginkgoales, which is represented by the only living species, Ginkgo biloba (common name: ginkgo). At least six discrepant placements of ginkgo have been proposed. This study aimed to use the chloroplast phylogenomic approach to examine possible factors that lead to such disagreeing placements. We found the sequence types used in the analyses as the most critical factor in the conflicting placements of ginkgo. In addition, the placement of ginkgo varied in the trees inferred from nucleotide (NU) sequences, which notably depended on breadth of taxon sampling, tree-building methods, codon positions, positions of Gnetopsida (common name: gnetophytes), and including or excluding gnetophytes in data sets. In contrast, the trees inferred from amino acid (AA) sequences congruently supported the monophyly of a ginkgo and Cycadales (common name: cycads) clade, regardless of which factors were examined. Our site-stripping analysis further revealed that the high substitution saturation of NU sequences mainly derived from the third codon positions and contributed to the variable placements of ginkgo. In summary, the factors we surveyed did not affect results inferred from analyses of AA sequences. Congruent topologies in our AA trees give more confidence in supporting the ginkgo–cycad sister-group hypothesis. PMID:23315384

Wu, Chung-Shien; Chaw, Shu-Miaw; Huang, Ya-Yi

2013-01-01

353

Newly discovered sister lineage sheds light on early ant evolution  

PubMed Central

Ants are the world's most conspicuous and important eusocial insects and their diversity, abundance, and extreme behavioral specializations make them a model system for several disciplines within the biological sciences. Here, we report the discovery of a new ant that appears to represent the sister lineage to all extant ants (Hymenoptera: Formicidae). The phylogenetic position of this cryptic predator from the soils of the Amazon rainforest was inferred from several nuclear genes, sequenced from a single leg. Martialis heureka (gen. et sp. nov.) also constitutes the sole representative of a new, morphologically distinct subfamily of ants, the Martialinae (subfam. nov.). Our analyses have reduced the likelihood of long-branch attraction artifacts that have troubled previous phylogenetic studies of early-diverging ants and therefore solidify the emerging view that the most basal extant ant lineages are cryptic, hypogaeic foragers. On the basis of morphological and phylogenetic evidence we suggest that these specialized subterranean predators are the sole surviving representatives of a highly divergent lineage that arose near the dawn of ant diversification and have persisted in ecologically stable environments like tropical soils over great spans of time. PMID:18794530

Rabeling, Christian; Brown, Jeremy M.; Verhaagh, Manfred

2008-01-01

354

Two sisters in the same dress: Heliconius cryptic species  

PubMed Central

Background Sister species divergence and reproductive isolation commonly results from ecological adaptation. In mimetic Heliconius butterflies, shifts in colour pattern contribute to pre- and post-mating reproductive isolation and are commonly correlated with speciation. Closely related mimetic species are therefore not expected, as they should lack several important sources of reproductive isolation. Results Here we present phenotypic, behavioral and genetic evidence for the coexistence of two sympatric 'cryptic' species near Florencia in the eastern Andes of Colombia that share the same orange rayed colour pattern. These represent H. melpomene malleti and a novel taxon in the H. cydno group, here designated as novel race of Heliconius timareta, Heliconius timareta florencia. No-choice mating experiments show that these sympatric forms have strong assortative mating (?96%) despite great similarity in colour pattern, implying enhanced divergence in pheromonal signals. Conclusion We hypothesize that these species might have resulted from recent convergence in colour pattern, perhaps facilitated by hybrid introgression of wing pattern genes. PMID:19040737

2008-01-01

355

The bacterial nucleoid: nature, dynamics and sister segregation.  

PubMed

Recent studies reveal that the bacterial nucleoid has a defined, self-adherent shape and an underlying longitudinal organization and comprises a viscoelastic matrix. Within this shape, mobility is enhanced by ATP-dependent processes and individual loci can undergo ballistic off-equilibrium movements. In Escherichia coli, two global dynamic nucleoid behaviors emerge pointing to nucleoid-wide accumulation and relief of internal stress. Sister segregation begins with local splitting of individual loci, which is delayed at origin, terminus and specialized interstitial snap regions. Globally, as studied in several systems, segregation is a multi-step process in which internal nucleoid state plays critical roles that involve both compaction and expansion. The origin and terminus regions undergo specialized programs partially driven by complex ATP burning mechanisms such as a ParAB Brownian ratchet and a septum-associated FtsK motor. These recent findings reveal strong, direct parallels among events in different systems and between bacterial nucleoids and mammalian chromosomes with respect to physical properties, internal organization and dynamic behaviors. PMID:25460806

Kleckner, Nancy; Fisher, Jay K; Stouf, Mathieu; White, Martin A; Bates, David; Witz, Guillaume

2014-11-01

356

Ecologically distinct dinosaurian sister group shows early diversification of Ornithodira.  

PubMed

The early evolutionary history of Ornithodira (avian-line archosaurs) has hitherto been documented by incomplete (Lagerpeton) or unusually specialized forms (pterosaurs and Silesaurus). Recently, a variety of Silesaurus-like taxa have been reported from the Triassic period of both Gondwana and Laurasia, but their relationships to each other and to dinosaurs remain a subject of debate. Here we report on a new avian-line archosaur from the early Middle Triassic (Anisian) of Tanzania. Phylogenetic analysis places Asilisaurus kongwe gen. et sp. nov. as an avian-line archosaur and a member of the Silesauridae, which is here considered the sister taxon to Dinosauria. Silesaurids were diverse and had a wide distribution by the Late Triassic, with a novel ornithodiran bauplan including leaf-shaped teeth, a beak-like lower jaw, long, gracile limbs, and a quadrupedal stance. Our analysis suggests that the dentition and diet of silesaurids, ornithischians and sauropodomorphs evolved independently from a plesiomorphic carnivorous form. As the oldest avian-line archosaur, Asilisaurus demonstrates the antiquity of both Ornithodira and the dinosaurian lineage. The initial diversification of Archosauria, previously documented by crocodilian-line archosaurs in the Anisian, can now be shown to include a contemporaneous avian-line radiation. The unparalleled taxonomic diversity of the Manda archosaur assemblage indicates that archosaur diversification was well underway by the Middle Triassic or earlier. PMID:20203608

Nesbitt, Sterling J; Sidor, Christian A; Irmis, Randall B; Angielczyk, Kenneth D; Smith, Roger M H; Tsuji, Linda A

2010-03-01

357

Median mental sinus in twins.  

PubMed

Sinus on the chin can be the result of a chronic apical abscess due to pulp necrosis of a mandibular anterior tooth. The tooth is usually asymptomatic, and a dental cause is therefore not apparent to the patient or the unsuspecting clinician. Not infrequently, the patient may seek treatment from a dermatologist or general surgeon instead of a dentist. Excision and repair of the fistula may be carried out with subsequent breakdown because the dental pathology is not removed. This paper reports the presence of median mental sinus of dental origin in twins. One case healed following root canal therapy while the other required both root canal therapy and surgery to eliminate the infection. PMID:10765768

Ong, S T; Ngeow, W C

1999-05-01

358

Genomic and epigenomic analyses of monozygotic twins discordant for congenital renal agenesis.  

PubMed

Monozygotic twins have been widely studied to distinguish genetic and environmental factors in the pathogenesis of human diseases. For renal agenesis, the one-sided absence of renal tissue, the relative contributions of genetic and environmental factors to its pathogenesis are still unclear. In this study of a pair of monozygotic twins discordant for congenital renal agenesis, the genomic profile was analyzed from a set of blood samples using high-throughput exome-capture sequencing to detect single-nucleotide polymorphisms (SNPs), copy number variations (CNVs), and insertions and deletions (indels). Also, an epigenomic analysis used reduced-representation bisulfite sequencing to detect differentially methylated regions (DMRs). No discordant SNPs, CNVs, or indels were confirmed, but 514 DMRs were detected. KEGG analysis indicated the DMRs localized to 10 signaling pathways and 25 genes, including the mitogen-activated protein kinase pathway and 6 genes (FGF18, FGF12, PDGFRA, MAPK11, AMH, CTBP1) involved in organ development. Although methylation results from our adult patient and her sister may not represent the pattern that was present during kidney development, we could at least confirm a lack of obvious differences at the genome level, which suggests that nongenetic factors may be involved in the pathogenesis of renal agenesis. PMID:24583054

Jin, Meiling; Zhu, Shida; Hu, Panpan; Liu, Dongbing; Li, Qinggang; Li, Zuoxiang; Zhang, Xueguang; Xie, Yuansheng; Chen, Xiangmei

2014-07-01

359

When Your Brother or Sister Has Cancer: A Guide for Teens  

Cancer.gov

Tips on what to say to your friends, how to deal with stress, and where to find support – as well as information about cancer and cancer treatments, for young people who have a brother or sister with cancer.

360

A Seamless Garment of Eco-Justice: Green Sisters in Kansas  

E-print Network

with insufficient education and minimal supports. The stress on the communities and individuals was unsustainable. The Sister Formation Conference, precursor to the Leadership Conference of Women Religious, was formed in 1954 to address the increasing problems...

Myslivy, Rachel Ann Boeckman

2013-12-31

361

20 CFR 725.222 - Conditions of entitlement; parent, brother, or sister.  

Code of Federal Regulations, 2011 CFR

...pneumoconiosis at the time of death or to have died due to pneumoconiosis. A surviving dependent parent, brother or sister of a miner whose claim is filed...by a spouse, child, or parent at the time of such miner's...

2011-04-01

362

20 CFR 725.225 - Determination of dependency; parent, brother, or sister.  

Code of Federal Regulations, 2011 CFR

...Conditions, and Duration of Entitlement Conditions and Duration of Entitlement: Miner's Dependents...725.225 Determination of dependency; parent, brother, or sister...immediately prior to the miner's death: (a) The...

2011-04-01

363

20 CFR 725.222 - Conditions of entitlement; parent, brother, or sister.  

Code of Federal Regulations, 2010 CFR

...pneumoconiosis at the time of death or to have died due to pneumoconiosis. A surviving dependent parent, brother or sister of a miner whose claim is filed...by a spouse, child, or parent at the time of such miner's...

2010-04-01

364

20 CFR 725.222 - Conditions of entitlement; parent, brother, or sister.  

Code of Federal Regulations, 2012 CFR

...pneumoconiosis at the time of death or to have died due to pneumoconiosis. A surviving dependent parent, brother or sister of a miner whose claim is filed...by a spouse, child, or parent at the time of such miner's...

2012-04-01

365

20 CFR 725.225 - Determination of dependency; parent, brother, or sister.  

Code of Federal Regulations, 2012 CFR

...Conditions, and Duration of Entitlement Conditions and Duration of Entitlement: Miner's Dependents...725.225 Determination of dependency; parent, brother, or sister...immediately prior to the miner's death: (a) The...

2012-04-01

366

20 CFR 725.225 - Determination of dependency; parent, brother, or sister.  

...Conditions, and Duration of Entitlement Conditions and Duration of Entitlement: Miner's Dependents...725.225 Determination of dependency; parent, brother, or sister...immediately prior to the miner's death: (a) The...

2014-04-01

367

20 CFR 725.225 - Determination of dependency; parent, brother, or sister.  

Code of Federal Regulations, 2010 CFR

...Conditions, and Duration of Entitlement Conditions and Duration of Entitlement: Miner's Dependents...725.225 Determination of dependency; parent, brother, or sister...immediately prior to the miner's death: (a) The...

2010-04-01

368

20 CFR 725.225 - Determination of dependency; parent, brother, or sister.  

Code of Federal Regulations, 2013 CFR

...Conditions, and Duration of Entitlement Conditions and Duration of Entitlement: Miner's Dependents...725.225 Determination of dependency; parent, brother, or sister...immediately prior to the miner's death: (a) The...

2013-04-01

369

20 CFR 725.222 - Conditions of entitlement; parent, brother, or sister.  

Code of Federal Regulations, 2013 CFR

...pneumoconiosis at the time of death or to have died due to pneumoconiosis. A surviving dependent parent, brother or sister of a miner whose claim is filed...by a spouse, child, or parent at the time of such miner's...

2013-04-01

370

VACTERL association with a rare vertebral anomaly (butterfly vertebra) in a case of monochorionic twin.  

PubMed

The VATER/VACTERL association is typically defined by the presence of at least three of the following congenital malformations: vertebral anomalies, anal atresia, cardiac malformations, tracheo-esophageal fistula, renal anomalies, and limb abnormalities (13). We report a rare case of a monochorionic twin gestation in which one of the infants had VACTERL association. Antenatal ultrasound showed bilateral renal dysplasia and cardiac anomaly (ASD) in twin A. Twin A was noted to have the following anomalies: a single umbilical artery, limb anomaly (right hand preaxial polydactyly), vertebral anomalies (T9 and T11 butterfly vertebras, bilateral renal agenesis, bladder agenesis, anal and urethral atresia. A normal-sized stomach and normal amount of amniotic fluid were observed during the prenatal period with no other anomalies. Twin B (male) was healthy and no cardiac, renal, or congenital anomalies were demonstrated on ultrasound and physical examination. Infant A was also diagnosed as having VACTERL association because he had five of the core anomalies (V, A, C, R, L) of VACTERL association. Butterfly vertebra is an uncommon congenital spinal anomaly. To the best of our knowledge, our patient is the second case VACTERL association with butterfly vertebra in the literature. PMID:25059024

Sandal, G; Aslan, N; Duman, L; Ormeci, A R

2014-01-01

371

Prevention of preterm delivery in twin pregnancy.  

PubMed

The incidence of twin gestation has increased markedly over the past decades, mostly because of increased use of assisted reproductive technologies. Twin pregnancies are at increased risk of preterm delivery (i.e. birth before 37 weeks of gestation). Multiple gestations therefore account for 2-3% of all pregnancies but constitute at least 10% of cases of preterm delivery. Complications from preterm birth are not limited to the neonatal period, such as in retinopathy of prematurity, intraventricular haemorrhage, necrotising enterocolitis, respiratory disorder and sepsis; they can also constitute sequelae such as abnormal neurophysiological development in early childhood and underachievement in school. Several treatment modalities have been proposed in singleton high-risk pregnancies. The mechanism of initiating labour may, however, be different in singleton and twin gestations. Therefore, it is mandatory to evaluate the proposed treatments in randomised trials of multiple gestations. In this chapter, we describe the results of trials to prevent preterm delivery in twin pregnancies. PMID:24378186

Rode, Line; Tabor, Ann

2014-02-01

372

A twin paradox for 'clever' students  

E-print Network

We discuss the twin paradox or the clock paradox under the small velocity approximation of special relativity. In this paper the traveller twin of the standard twin parable sets out with a non-relativistic speed for the trip leaving behind the stay-at-home one on earth and continues up to a distance and finally returns home with the same speed when the siblings can compare their ages or their initially synchronized wrist watches. The common knowledge that at small velocities the length contraction and time dilation effects of special relativity can be ignored so that the world becomes essentially classical, tends to lead to a paradox in connection with the twin problem, which a "clever" student eventually discovers. After discussing and resolving the issue, some more related paradoxes have been presented. The resolution of all these problems provides some additional insight into the century old paradox.

S. K. Ghosal; Saroj Nepal; Debarchana Das

2005-11-23

373

Asymmetric twins in rhombohedral boron carbide  

SciTech Connect

Superhard materials consisting of light elements have recently received considerable attention because of their ultrahigh specific strength for a wide range of applications as structural and functional materials. However, the failure mechanisms of these materials subjected to high stresses and dynamic loading remain to be poorly known. We report asymmetric twins in a complex compound, boron carbide (B{sub 4}C), characterized by spherical-aberration-corrected transmission electron microscopy. The atomic structure of boron-rich icosahedra at rhombohedral vertices and cross-linked carbon-rich atomic chains can be clearly visualized, which reveals unusual asymmetric twins with detectable strains along the twin interfaces. This study offers atomic insights into the structure of twins in a complex material and has important implications in understanding the planar defect-related failure of superhard materials under high stresses and shock loading.

Fujita, Takeshi, E-mail: tfujita@wpi-aimr.tohoku.ac.jp; Guan, Pengfei; Madhav Reddy, K.; Hirata, Akihiko; Guo, Junjie [WPI Advanced Institute for Materials Research, Tohoku University, Sendai 980-8577 (Japan); Chen, Mingwei, E-mail: mwchen@wpi-aimr.tohoku.ac.jp [WPI Advanced Institute for Materials Research, Tohoku University, Sendai 980-8577 (Japan); State Key Laboratory of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai 200030 (China)

2014-01-13

374

Shock Driven Twinning in Tantalum Single Crystals  

SciTech Connect

Recovery based observations of high pressure material behavior generated under high explosively driven flyer based loading conditions are reported. Two shock pressures, 25, and 55 GPa and four orientations {l_brace}(100), (110), (111), (123){r_brace} were considered. Recovered material was characterized using electron backscatter diffraction along with a limited amount of transmission electron microscopy to assess the occurrence of twinning under each test condition. Material recovered from 25 GPa had a very small fraction of twinning for the (100), (110), and (111) oriented crystals while a more noticeable fraction of the (123) oriented crystal was twinned. Material recovered from 55 GPa showed little twinning for (100) orientation slightly more for the (111) orientation and a large area fraction for the (123) orientation. The EBSD and TEM observations of the underlying deformation substructure are rationalized by comparing with previous static and dynamic results.

McNaney, J M; HSUING, L M; Barton, N R; Kumar, M

2009-07-20

375

Spectroscopic study of solar twins and analogues  

E-print Network

Context. Many large stellar surveys have been and are still being carried out, providing huge amounts of data, for which stellar physical parameters will be derived. Solar twins and analogues provide a means to test the calibration of these stellar catalogues because the Sun is the best-studied star and provides precise fundamental parameters. Solar twins should be centred on the solar values. Aims. This spectroscopic study of solar analogues selected from the Geneva-Copenhagen Survey (GCS) at a resolution of 48,000 provides effective temperatures and metallicities for these stars. We test whether our spectroscopic parameters, as well as the previous photometric calibrations, are properly centred on the Sun. In addition, we search for more solar twins in our sample. Methods. The methods used in this work are based on literature methods for solar twin searches and on methods we developed in previous work to distinguish the metallicity-temperature degeneracies in the differential comparison of spectra of solar ...

Datson, Juliet; Portinari, Laura

2014-01-01

376

Chondrodermatitis nodularis chronica helicis in monozygotic twins.  

PubMed

Chondrodermatitis nodularis chronica helicis (CNCH) is a benign inflammatory nodule of the helix. Patients report severe tenderness upon pressure. Commonly seen in middle-aged men, there are no reports of this disease in twins. We report middle-aged male monozygotic twins who simultaneously developed CNCH. This suggests, but does not prove, the possibility of a hereditary factor in the pathogenesis of CNCH. PMID:19175786

Chan, H P; Neuhaus, I M; Maibach, H I

2009-04-01

377

Twins Among the Low Mass Spectroscopic Binaries  

E-print Network

We report an analysis of twins of spectral types F or later in the 9th Catalog of Spectroscopic Binaries (SB9). Twins, the components of binaries with mass ratio within 2% of 1.0, are found among the binaries with primaries of F and G spectral type. They are most prominent among the binaries with periods less than 43 days, a cutoff first identified by Lucy. Within the subsample of binaries with Ptwins do not differ from the other binaries in their distributions of periods (median P~7d), masses, or orbital eccentricities. Combining the mass ratio distribution in the SB9 in the mass range 0.6 to 0.85 Msun with that measured by Mazeh et al. for binaries in the Carney-Latham high proper motion survey, we estimate that the frequency of twins in a large sample of spectroscopic binaries is about 3%. Current theoretical understanding indicates that accretion of high specific angular momentum material by a protobinary tends to equalize its masses. We speculate that the excess of twins is produced in those star forming regions where the accretion processes were able to proceed to completion for a minority of protobinaries. This predicts that the components of a young twin may appear to differ in age and that, in a sample of spectroscopic binaries in a star formation region, the twins are, on average, older than the binaries with mass ratios much smaller than 1.

M. Simon; R. C. Obbie

2008-12-12

378

Imperfect twinning: a clinical and ethical dilemma  

PubMed Central

OBJECTIVE To review the history, epidemiology, etiology, gestational aspects, diagnosis and prognosis of imperfect twinning. DATA SOURCES Scientific articles were searched in PubMed, SciELO and Lilacs databases, using the descriptors "conjoined twins", "multiple pregnancy", "ultrasound", "magnetic resonance imaging" and "prognosis". The research was not delimited to a specific period of time and was supplemented with bibliographic data from books. DATA SYNTHESIS: The description of conjoined twins is legendary. The estimated frequency is 1/45,000-200,000 births. These twins are monozygotic, monochorionic and usually monoamniotic. They can be classified by the most prominent fusion site, by the symmetry between the conjoined twins or by the sharing structure. The diagnosis can be performed in the prenatal period or after birth by different techniques, such as ultrasound, magnetic resonance imaging and echocardiography. These tests are of paramount importance for understanding the anatomy of both fetuses/children, as well as for prognosis and surgical plan determination. CONCLUSIONS Although imperfect twinning is a rare condition, the prenatal diagnosis is very important in order to evaluate the fusion site and its complexity. Hence, the evaluation of these children should be multidisciplinary, involving mainly obstetricians, pediatricians and pediatric surgeons. However, some decisions may constitute real ethical dilemmas, in which different points should be discussed and analyzed with the health team and the family. PMID:24142323

Denardin, Daniela; Telles, Jorge Alberto B.; Betat, Rosilene da Silveira; Fell, Paulo Renato K.; da Cunha, André Campos; Targa, Luciano Vieira; Zen, Paulo Ricardo G.; Rosa, Rafael Fabiano M.

2013-01-01

379

The Mid-Atlantic Twin Registry, revisited.  

PubMed

The Mid-Atlantic Twin Registry (MATR) is a population-based registry of more than 56,000 twins primarily born or living in Virginia, North Carolina, and South Carolina. The MATR employs several methods of ascertaining twins, and devotes considerable resources to tracking and maintaining communication with MATR participants. Researchers may utilize the MATR for administration of research services including study recruitment, collection of DNA, archival data set creation, as well as data collection through mailed, phone, or online surveys. In addition, the MATR houses the MATR Repository, with over 1,200 blood samples available for researchers interested in DNA genotyping. For over 35 years MATR twins have participated in research studies with investigators from diverse scientific disciplines and various institutions. These studies, which have resulted in numerous publications, have covered a range of topics, including the human microbiome, developmental psychopathology, depression, anxiety, substance use, epigenetics of aging, children of twins, pre-term birth, social attitudes, seizures, eating disorders, as well as sleep homeostasis. Researchers interested in utilizing twins are encouraged to contact the MATR to discuss potential research opportunities. PMID:23218199

Lilley, Emily C H; Silberg, Judy L

2013-02-01

380

Substantial genetic link between IQ and working memory: implications for molecular genetic studies on schizophrenia. the European twin study of schizophrenia (EUTwinsS).  

PubMed

While evidence is accumulating to support specific neurocognitive deficits as putative endophenotypes for schizophrenia, the heritability of these deficits in healthy subjects and whether they share common genetic influences, is not well established. In the present study, 529 healthy adult twins from two centers within the European Twin Study Network on Schizophrenia (EUTwinsS) were assessed on two domains that are consistently found to be particularly compromised in schizophrenia. Specifically, Intellectual Quotient Score (IQ) and the Letter-Number Sequencing Test (LNS), a measure of working memory, were measured in all twins. Latent variable components were explored through structural equation modeling, and common genetic underpinnings were examined using bivariate analyses. Results showed that the phenotypic correlation between IQ and working memory was almost entirely attributed to shared genetic variance (95.5%). We discuss the potential use of a combined measure of IQ and working memory to improve the power of molecular studies in detecting the genetic mechanisms underlying schizophrenia. PMID:23650229

Goldberg, Ximena; Alemany, Silvia; Rosa, Araceli; Picchioni, Marco; Nenadic, Igor; Owens, Sheena F; Rijsdijk, Fruhling; Rebollo, Irene; Sauer, Heinrich; Murray, Robin M; Fańanás, Lourdes; Toulopoulou, Timothea

2013-06-01

381

Characterization of twinning in electrodeposited Ni-Mn alloys.  

SciTech Connect

Twinning is ubiquitous in electroplated metals. Here, we identify and discuss unique aspects of twinning found in electrodeposited Ni-Mn alloys. Previous reports concluded that the twin boundaries effectively refine the grain size, which enhances mechanical strength. Quantitative measurements from transmission electron microscopy (TEM) images show that the relative boundary length in the as-plated microstructure primarily comprises twin interfaces. Detailed TEM characterization reveals a range of length scales associated with twinning beginning with colonies ({approx}1000 nm) down to the width of individual twins, which is typically <50 nm. We also consider the connection between the crystallographic texture of the electrodeposit and the orientation of the twin planes with respect to the plating direction. The Ni-Mn alloy deposits in this work possess a 110-fiber texture. While twinning can occur on {l_brace}111{r_brace} planes either perpendicular or oblique to the plating direction in {l_brace}110{r_brace}-oriented grains, plan-view TEM images show that twins form primarily on those planes parallel to the plating direction. Therefore, grains enclosed by twins and multiply twinned particles are produced. Another important consequence of a high twin density is the formation of large numbers of twin-related junctions. We measure an area density of twin junctions that is comparable to the density of dislocations in a heavily cold-worked metal.

Yang, Nancy Y. C.; Medlin, Douglas L.; Kelly, James J.; Lucadamo, Gene Anthony; Talin, Albert Alec

2004-06-01

382

Endoscopic laser surgery versus serial amniocenteses in the treatment of severe twin-twin transfusion syndrome  

Microsoft Academic Search

Objective: Severe twin-twin transfusion can be treated by either serial amniocenteses with removal of large volumes of amniotic fluid or by endoscopic laser coagulation of the communicating vessels. We investigated the benefit of laser surgery in comparison to serial amniocenteses in terms of pregnancy outcome. Study Design: The data used in this comparative study were collected from 116 patients with

Kurt Hecher; Hanno Plath; Thomas Bregenzer; Manfred Hansmann; Bernhard J. Hackelöer

1999-01-01

383

Langevin's `Twin Paradox' paper revisited  

E-print Network

An in-depth and mathematically-detailed analysis of Langevin's popular 1911 article on the special theory of relativity is presented. For the reader's convenience, English translations of large parts of the original French text are given. The self-contradictory nature of many of Langevin's assertions is pointed out. Of special interest is the analysis of the exchange of light signals between the travelling and stay-at-home twins in Langevin's thought experiment, in which antinomies are found in the conventional relativistic treatment. Their resolution shows that the physical basis of the differential aging effect in the experiment is not `length contraction', as in the conventional interpretation, but instead the application of the correct relative velocity transformation formula. The spurious nature of the correlated `length contraction' and `relativity of simultaneity' effects of conventional special relativity is also demonstrated. In consequence, an argument given, claiming to demonstrate that an upper limit of $c$ on the speed of any physical signal is required by causality, is invalid. Its conclusion is also in contradiction with astronomical observations and the results of a recent experiment.

J. H. Field

2008-11-21

384

The Onsala Twin Telescope Project  

NASA Astrophysics Data System (ADS)

This paper described the Onsala Twin Telescope project. The project aims at the construction of two new radio telescopes at the Onsala Space Observatory, following the VLBI2010 concept. The project starts in 2013 and is expected to be finalized within 4 years. Z% O. Rydbeck. Chalmers Tekniska Högskola, Göteborg, ISBN 91-7032-621-5, 407-823, 1991. B. Petrachenko, A. Niell, D. Behrend, B. Corey, J. Böhm, P. Charlot, A. Collioud, J. Gipson, R. Haas, Th. Hobiger, Y. Koyama, D. MacMillan, Z. Malkin, T. Nilsson, A. Pany, G. Tuccari, A. Whitney, and J. Wresnik. Design Aspects of the VLBI2010 System. NASA/TM-2009-214180, 58 pp., 2009. R. Haas, G. Elgered, J. Löfgren, T. Ning, and H.-G. Scherneck. Onsala Space Observatory - IVS Network Station. In K. D. Baver and D. Behrend, editors, International VLBI Service for Geodesy and Astrometry 2011 Annual Report, NASA/TP-2012-217505, 88-91, 2012. H.-G. Scherneck, G. Elgered, J. M. Johansson, and B. O. Rönnäng. Phys. Chem. Earth, Vol. 23, No. 7-8, 811-823, 1998. A. R. Whitney. Ph.D. thesis, Dept. of Electrical engineering, MIT Cambridge, MA., 1974. B. A. Harper, J. D. Kepert, and J. D. Ginger. Guidelines for converting between various wind averaging periods in tropical cyclone conditions. WMO/TD-No. 1555, 64 pp., 2010 (available at \\url{http://www.wmo.int/pages/prog/www/tcp/documents/WMO_TD_1555_en.pdf})

Haas, R.

2013-08-01

385

A Holographic Twin Higgs Model  

E-print Network

We present a UV completion of the twin Higgs idea in the framework of holographic composite Higgs. The SM contribution to the Higgs potential is effectively cut off by the SM-singlet mirror partners at the sigma-model scale f, naturally allowing for m_{KK} beyond the LHC reach. The bulk symmetry is SU(7) X SO(8), broken on the IR brane into SU(7) X SO(7) and on the UV brane into (SU(3) X SU(2) X U(1))^{SM} X (SU(3) X SU(2) X U(1))^{mirror} X Z2. The field content on the UV brane is the SM, extended by a sector transforming under the mirror gauge group, with the Z2 exchanging the two sectors. An additional Z2 breaking term is holographically generated to reproduce the Higgs mass and VEV, with a mild O(10%) tuning. This model has no trace at the LHC, but can by probed by precision Higgs measurements at future lepton colliders, and by direct searches for KK excitations at a 100 TeV collider.

Michael Geller; Ofri Telem

2014-11-11

386

The Contribution of Diet and Genotype to Iron Status in Women: A Classical Twin Study  

PubMed Central

This is the first published report examining the combined effect of diet and genotype on body iron content using a classical twin study design. The aim of this study was to determine the relative contribution of genetic and environmental factors in determining iron status. The population was comprised of 200 BMI- and age-matched pairs of MZ and DZ healthy twins, characterised for habitual diet and 15 iron-related candidate genetic markers. Variance components analysis demonstrated that the heritability of serum ferritin (SF) and soluble transferrin receptor was 44% and 54% respectively. Measured single nucleotide polymorphisms explained 5% and selected dietary factors 6% of the variance in iron status; there was a negative association between calcium intake and body iron (p?=?0.02) and SF (p?=?0.04). PMID:24391736

Fairweather-Tait, Susan J.; Guile, Geoffrey R.; Valdes, Ana M.; Wawer, Anna A.; Hurst, Rachel; Skinner, Jane; Macgregor, Alexander J.

2013-01-01

387

Deformation twinning mechanisms in FCC and HCP metals  

SciTech Connect

We report the recent work on twinning and detwinning in fcc and hcp metals based on the in situ and ex situ TEM observations and molecular dynamics simulations. Three aspects are discussed in this paper. (1) Detwinning in single-phase Cu with respect to growth twins, (2) deformation twinning in Ag-Cu composites, and (3) deformation twinning mechanisms in hcp metals. The main conclusion is that atomic structures of interfaces (twin boundaries, two-phases interface, and grain boundaries) play a crucial role in nucleating and propagating of deformation twins.

Wang, Jian [Los Alamos National Laboratory; Tome, Carlos N [Los Alamos National Laboratory; Beyerlein, Irene J [Los Alamos National Laboratory; Misra, Amit [Los Alamos National Laboratory; Mara, N [Los Alamos National Laboratory

2011-01-31

388

Generation of Brazil and Dauphiné twins in synthetic amethysts  

NASA Astrophysics Data System (ADS)

The generation of both Brazil and Dauphiné twins is triggered by strain fields associated with the fluctuation of growth parameters when solid inclusions of goethite (?) are precipitated on to a growth surface. Brazil twins are generated either directly from solid inclusions of smaller size or dislocations originating therefrom, whereas Dauphiné twins are generated only directly from solid inclusions of larger size. Precipitation of polymerized embryonic particles of SiO2 on the surface of solid inclusions is considered to be responsible for the generation of Brazil twins, whereas for Dauphiné twins it is necessary that embryonic particles precipitated in twin orientation on the surface of solid inclusions grow beyond a critical size.

Sunagawa, Ichiro; Taijing, Lu; Balitsky, V. S.

1990-09-01

389

"Healthy" Human Development Indices  

ERIC Educational Resources Information Center

In the Human Development Index (HDI), life expectancy is the only indicator used in modeling the dimension "a long and healthy life". Whereas life expectancy is a direct measure of quantity of life, it is only an indirect measure of healthy years lived. In this paper we attempt to remedy this omission by introducing into the HDI the morbidity…

Engineer, Merwan; Roy, Nilanjana; Fink, Sari

2010-01-01

390

Healthy Homes Tools  

ERIC Educational Resources Information Center

Extension is focusing on healthy homes programming. Extension educators are not qualified to diagnose consumers' medical problems as they relate to housing. We cannot give medical advice. Instead, we can help educate consumers about home conditions that may affect their well-being. Extension educators need appropriate healthy homes tools to…

Peek, Gina; Lyon, Melinda; Russ, Randall

2012-01-01

391

Digital Data for Volcano Hazards of the Three Sisters Region, Oregon  

USGS Publications Warehouse

Three Sisters is one of three active volcanic centers that lie close to rapidly growing communities and resort areas in Central Oregon. The major composite volcanoes of this area are clustered near the center of the region and include South Sister, Middle Sister, and Broken Top. Additionally, hundreds of mafic volcanoes are scattered throughout the Three Sisters area. These range from small cinder cones to large shield volcanoes like North Sister and Belknap Crater. Hazardous events include landslides from the steep flanks of large volcanoes and floods, which need not be triggered by eruptions, as well as eruption-triggered events such as fallout of tephra (volcanic ash) and lava flows. A proximal hazard zone roughly 20 kilometers (12 miles) in diameter surrounding the Three Sisters and Broken Top could be affected within minutes of the onset of an eruption or large landslide. Distal hazard zones that follow river valleys downstream from the Three Sisters and Broken Top could be inundated by lahars (rapid flows of water-laden rock and mud) generated either by melting of snow and ice during eruptions or by large landslides. Slow-moving lava flows could issue from new mafic volcanoes almost anywhere within the region. Fallout of tephra from eruption clouds can affect areas hundreds of kilometers (miles) downwind, so eruptions at volcanoes elsewhere in the Cascade Range also contribute to volcano hazards in Central Oregon. Scientists at the Cascades Volcano Observatory created a geographic information system (GIS) data set which depicts proximal and distal lahar hazard zones as well as a regional lava flow hazard zone for Three Sisters (USGS Open-File Report 99-437, Scott and others, 1999). The various distal lahar zones were constructed from LaharZ software using 20, 100, and 500 million cubic meter input flow volumes. Additionally, scientists used the depositional history of past events in the Three Sisters Region as well as experience and judgment derived from the study of volcanoes to help construct the regional hazard zone.

Schilling, S.P.; Doelger, S.; Scott, W.E.; Iverson, R.M.

2008-01-01

392

Identifying possible sister groups of Cryptocercidae+Isoptera: A combined molecular and morphological phylogeny of Dictyoptera.  

PubMed

Termites (Isoptera) offer an alternative model for the development of eusociality which is not dependent on a high degree of relatedness as found between sisters in hymenopterans (bees, wasps, ants). Recent phylogenetic studies have established that termites belong within the cockroaches as sister to the subsocial Cryptocercidae. Cryptocercidae shares several important traits with termites, thus we need to understand the phylogenetic position of Cryptocercidae+Isoptera to determine how these traits evolved. However, placement of Cryptocercidae+Isoptera is still uncertain. We used both molecular (12S, 16S, COII, 18S, 28S, H3) and morphological characters to reconstruct the phylogeny of Dictyoptera. We included all previously suggested sister groups of Cryptocercidae+Isoptera as well as taxa which might represent additional major cockroach lineages. We used Bayes factors to test different sister groups for Cryptocercidae+Isoptera and assessed character support for the consensus tree based on morphological characters and COII amino acid data. We used the molecular data and fossil calibration to estimate divergence times. We found the most likely sister groups of Cryptocercidae+Isoptera to be Tryonicidae, Anaplecta or Tryonicidae+Anaplecta. Anaplecta has never previously been suggested as sister group or even close to Cryptocercidae+Isoptera, but was formerly placed in Blaberoidea as sister to the remaining taxa. Topological tests firmly supported our new placement of Anaplecta. We discuss the morphological characters (e.g. retractable genitalic hook) that have contributed to the previous placement of Anaplecta in Blaberoidea as well as the factors that might have contributed to a parallel development of genitalic features in Anaplecta and Blaberoidea. Cryptocercidae+Isoptera is placed in a clade with Tryonicidae, Anaplecta and possibly Lamproblattidae. Based on this, we suggest that wood-feeding, and the resultant need to conserve nitrogen, may have been an important factor in the development of termite eusociality. Nocticolidae was placed as sister group to Latindia+Paralatindia (both Corydiidae), this clade was in turn placed as sister group to the remaining Corydiidae. The Nocticolidae+Corydiidae clade is supported by both morphological and COII amino acid changes. Our divergence time estimates placed the split between Mantodea and Blattodea at 273mya (middle Permian) and the splits between the major blattodean lineages no later than 200mya (end of Triassic). PMID:25194324

Djernćs, Marie; Klass, Klaus-Dieter; Eggleton, Paul

2014-09-01

393

Metabolome and fecal microbiota in monozygotic twin pairs discordant for weight: a Big Mac challenge.  

PubMed

Postprandial responses to food are complex, involving both genetic and environmental factors. We studied postprandial responses to a Big Mac meal challenge in monozygotic co-twins highly discordant for body weight. This unique design allows assessment of the contribution of obesity, independent of genetic liability. Comprehensive metabolic profiling using 3 analytical platforms was applied to fasting and postprandial serum samples from 16 healthy monozygotic twin pairs discordant for weight (body mass index difference >3 kg/m(2)). Nine concordant monozygotic pairs were examined as control pairs. Fecal samples were analyzed to assess diversity of the major bacterial groups by using 5 different validated bacterial group specific denaturing gradient gel electrophoresis methods. No differences in fecal bacterial diversity were detected when comparing co-twins discordant for weight (ANOVA, P<0.05). We found that within-pair similarity is a dominant factor in the metabolic postprandial response, independent of acquired obesity. Branched chain amino acids were increased in heavier as compared with leaner co-twins in the fasting state, but their levels converged postprandially (paired t tests, FDR q<0.05). We also found that specific bacterial groups were associated with postprandial changes of specific metabolites. Our findings underline important roles of genetic and early life factors in the regulation of postprandial metabolite levels.-Bondia-Pons, I., Maukonen, J., Mattila, I., Rissanen, A., Saarela, M., Kaprio, J., Hakkarainen, A., Lundbom, J., Lundbom, N., Hyötyläinen, T., Pietiläinen, K. H., Oreši?, M. Metabolome and fecal microbiota in monozygotic twin pairs discordant for weight: a Big Mac challenge. PMID:24846387

Bondia-Pons, Isabel; Maukonen, Johanna; Mattila, Ismo; Rissanen, Aila; Saarela, Maria; Kaprio, Jaakko; Hakkarainen, Antti; Lundbom, Jesper; Lundbom, Nina; Hyötyläinen, Tuulia; Pietiläinen, Kirsi H; Oreši?, Matej

2014-05-20

394

A Twin Study of Alcohol Dependence, Binge Eating, and Compensatory Behaviors  

PubMed Central

Objective: Rates of alcohol dependence are elevated in women with eating disorders who engage in binge eating or compensatory behaviors compared with women with eating disorders who do not report binge eating or compensatory behaviors and with healthy controls. Alcohol dependence, binge eating, and compensatory behaviors are heritable; however, it is unclear whether a shared genetic liability contributes to the phenotypic association among these traits, and little information exists regarding this shared liability in men. We investigated genetic and environmental correlations among alcohol dependence, binge eating, and compensatory behaviors in male and female twins. Method: Participants included 5,993 same- and opposite-sex twins from the Australian Twin Registry who completed a modified version of the Semi-Structured Assessment for the Genetics of Alcoholism that assessed lifetime alcohol dependence and binge eating as defined in the Diagnostic and Statistical Manual of Mental Disorders, Third Edition, Revised. Compensatory behaviors were assessed via a general health questionnaire in women only. Biometrical twin models estimated genetic and environmental influences on alcohol dependence, binge eating, and compensatory behaviors. Results: In women, the multivariate twin model suggested that additive genetic and nonshared environmental effects influenced alcohol dependence, binge eating, and compensatory behaviors, with heritability estimates ranging from 38% to 53%. The best-fitting sex-limitation model was a common effects model that equated all genetic and nonshared environmental influences in men and women. The heritability estimates were 50% and 38% for alcohol dependence and binge eating, respectively. Overall, there were significant genetic correlations between alcohol dependence and binge eating, alcohol dependence and compensatory behaviors, and binge eating and compensatory behaviors. Conclusions: These findings indicate that common genetic factors may underlie the vulnerability to alcohol dependence and the liability to binge eating and compensatory behaviors. PMID:23948525

Munn-Chernoff, Melissa A.; Duncan, Alexis E.; Grant, Julia D.; Wade, Tracey D.; Agrawal, Arpana; Bucholz, Kathleen K.; Madden, Pamela A. F.; Martin, Nicholas G.; Heath, Andrew C.

2013-01-01

395

The interaction between slip and twinning systems and the influence of twinning on the mechanical behavior of fcc metals and alloys  

Microsoft Academic Search

The analysis of twin-slip and twin-twin interactions in fcc crystals is reviewed using the method proposed by Sleeswyk and\\u000a Verbraak for the interactions between bcc twins. Slip or twinning dislocations impinging a twin boundary can generally be\\u000a incorporated into the obstacle twin through often unfavorable dislocation reactions. Transmission electron microscopy observations\\u000a are in agreement with the predicted mechanisms of stress

L. Rémy

1981-01-01

396

Two sisters reveal autosomal recessive inheritance of epidermodysplasia verruciformis: a case report  

PubMed Central

Background Epidermodysplasia verruciformis is a rare genodermatosis characterized by a unique susceptibility to cutaneous human papillomaviruses infection. Most patients show autosomal recessive patterns of inheritance. Case presentation We report a case of two sisters with clinically epidermodysplasia verruciformis specific lesions on the face, neck, trunk, and extremities. PCR analysis indicated the presence of human papillomavirus type 5 in the lesions. Electron microscopic examination showed viral-like particles in keratinocyte nuclei and the stratum corneum of the epidermodysplasia verruciformis lesions. In addition, we examined the EVER1 and EVER2 genes using eight different primer pairs without finding any nonsense or frameshift mutations in the gDNA from lymphocytes of the elder sister. Conclusions In this report, the patient’s parents did not have epidermodysplasia verruciformis lesions or a consanguineous marriage. EV did not develop in the elder sister until five years of age, so the parents did not perceive EV as an inherited disease. The probability that EV developed in both sisters was only 6.25%. Thus, it is rare for both sisters to develop epidermodysplasia verruciformis lesions considering that the parents were presumed to be carriers and the disease reveal an autosomal recessive pattern of inheritance. PMID:25048734

2014-01-01

397

Neuropsychological profiles of three sisters homozygous for the fragile X premutation  

SciTech Connect

Fragile X syndrome (fraX) is associated with an amplification of a CGG repeat within the fraX mental retardation (FMR-1) gene. We describe an exceptional family in which 3 adult sisters are homozygous for the FMR-1 premutation. Each sister inherited 2 premutation alleles (ca. 80 CGG repeats) from their biologically unrelated parents. The 3 sisters were administered measures of executive function, visual spatial, memory, and verbal skills. Deficiencies in the first 2 of these domains have been reported among females with the full mutation. The sisters` performances were compared with available normative data and with published group means for females affected by fraX. These women did not appear to have verbal or memory difficulties. None of the women demonstrated a global executive function deficit, and none had global deficits in spatial ability. The profiles of these sisters are consistent with reports that the fragile X premutation does not affect cognitive performance. 31 refs., 1 fig., 4 tabs.

Mazzocco, M.M.M. [Johns Hopkins School of Medicine, Baltimore, MD (United States)] [Johns Hopkins School of Medicine, Baltimore, MD (United States); Holden, J.J.A. [Ongwanada Resource Centre, Kingston, Ontario (Canada)] [Ongwanada Resource Centre, Kingston, Ontario (Canada)

1996-08-09

398

Mps1 kinase promotes sister-kinetochore bi-orientation by a tension-dependent mechanism.  

PubMed

Segregation of sister chromatids to opposite spindle poles during anaphase is dependent on the prior capture of sister kinetochores by microtubules extending from opposite spindle poles (bi-orientation). If sister kinetochores attach to microtubules from the same pole (syntelic attachment), the kinetochore-spindle pole connections must be re-oriented to be converted to proper bi-orientation. This re-orientation is facilitated by Aurora B kinase (Ipl1 in budding yeast), which eliminates kinetochore-spindle pole connections that do not generate tension. Mps1 is another evolutionarily conserved protein kinase, required for spindle-assembly checkpoint and, in some organisms, for duplication of microtubule-organizing centers. Separately from these functions, however, Mps1 has an important role in chromosome segregation. Here we show that, in budding yeast, Mps1 has a crucial role in establishing sister-kinetochore bi-orientation on the mitotic spindle. Failure in bi-orientation with inactive Mps1 is not due to a lack of kinetochore-spindle pole connections by microtubules, but due to a defect in properly orienting the connections. Mps1 promotes re-orientation of kinetochore-spindle pole connections and eliminates those that do not generate tension between sister kinetochores. We did not find evidence that Ipl1 regulates Mps1 or vice versa; therefore, they play similar, but possibly independent, roles in facilitating bi-orientation. PMID:18060784

Maure, Jean-François; Kitamura, Etsushi; Tanaka, Tomoyuki U

2007-12-18

399

NAE Twin Otter operations in FIFE 1989  

NASA Technical Reports Server (NTRS)

During the summer of 1989, the National Aeronautical Establishment (Canada) Twin Otter Atmospheric Research Aircraft was flow in support of the NASA sponsored First ISLSCP (International Satellite Land Surface Climatology Project) Field Experiment called FIFE-89. Airborne measurements of the fluxes of heat, momentum, water vapor and carbon dioxide were made during 16 flow-altitude flights over the FIFE project area in central Kansas. The Twin Otter operations in FIFE are documented and details are included on the instrumentation, software, flight procedures, atmospheric conditions and analysis methods. Comparisons of Twin Otter measured fluxes are made with those determined at several surface sites and with those made by other instrumented aircraft in the FIFE-87 measurements. Airborne flux measurements are related to run length, altitude, and environmental parameters such as vegetation type, temperature, and wind speed. One night flight was run in an attempt to measure the respiration component of the CO2 flux. The use of aircraft was studied for regional observations of fluxes and to relate these to satellite radiance measurements. Run average data are presented for all 285 flux runs flown by the Twin Otter in FIFE-89. This should serve as as a working reference for scientists utilizing Twin Otter data either directly of through the FIFE data archive.

Macpherson, J. I.

1990-01-01

400

A twin study of the effects of energy density and palatability on energy intake of individual foods  

Microsoft Academic Search

The relative effects of energy density and palatability on energy intake, and whether there are familial influences on these effects, are not known. We investigated this issue in 7 pairs of healthy, male monozygotic twins (mean±SD age 26.3±8.6 years, BMI 23.7±3.2 kg\\/m2) in a clinical study involving covert ad libitum feeding of high-fat (HF, ?40%) and low-fat (LF, ?20%) diets

Megan A. McCrory; Edward Saltzman; Barbara J. Rolls; Susan B. Roberts

2006-01-01

401

Elevated sister chromatid exchange frequencies in dividing human peripheral blood lymphocytes exposed to 50 Hz magnetic fields.  

PubMed

The in vitro cytomolecular technique, sister chromatid exchange (SCE), was applied to test the clastogenic potentiality of extremely low frequency (ELF) electromagnetic fields (EMFs) on human peripheral blood lymphocytes (HPBLs). SCE frequencies were scored in dividing peripheral blood lymphocytes (PBLs) from six healthy male blood donors in two rounds of experiments, R1 and R2, to determine reproducibility. Lymphocyte cultures in the eight experiments conducted in each round were exposed to 50 Hz sinusoidal (continuous or pulsed) or square (continuous or pulsed) MFs at field strengths of 1 microT or 1 mT for 72 h. A significant increase in the number of SCEs/cell in the grouped experimental conditions compared to the controls was observed in both rounds. The highest SCE frequency in R1 was 10.03 for a square continuous field, and 10.39 for a square continuous field was the second highest frequency in R2. DNA crosslinking at the replication fork is proposed as a model which could explain the mechanistic link between ELF EMF exposure and increased SCE frequency. PMID:17080456

Wahab, M A; Podd, J V; Rapley, B I; Rowland, R E

2007-05-01

402

Twins and their boundaries during homoepitaxy on Ir(111)  

SciTech Connect

The growth and annealing behavior of strongly twinned homoepitaxial films on Ir(111) have been investigated by scanning tunneling microscopy, low-energy electron diffraction, and surface x-ray diffraction. In situ surface x-ray diffraction during and after film growth turned out to be an efficient tool for the determination of twin fractions in multilayer films and to unravel the nature of lateral twin crystallite boundaries. The annealing of the twin structures is shown to take place in a two-step process; first, the length of the lateral twin crystallite boundaries is reduced, without affecting the amount of twinned material, and then, at much higher temperatures, the twins themselves anneal. Within moderately annealed films lateral twin crystallite boundaries are visible at the film surface as fractional steps from which strain fields extend. The nature of these boundaries is discussed.

Bleikamp, Sebastian; Michely, Thomas [II Physikalisches Institut, Universitaet zu Koeln, D-50937 Koeln (Germany); Coraux, Johann [II Physikalisches Institut, Universitaet zu Koeln, D-50937 Koeln (Germany); Institut Neel, CNRS-UJF, 25 Rue des Martyrs, B.P. 166, F-38042 Grenoble Cedex 9 (France); Robach, Odile; Renaud, Gilles [Commissariat a l'Energie Atomique, Institut Nanosciences et Cryog enie, 17 Avenue des Martyrs, F-38054 Grenoble Cedex 9 (France)

2011-02-01

403

3. OVERALL VIEW OF TWIN POTS RESERVOIR, LOOKING SOUTHEAST ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. OVERALL VIEW OF TWIN POTS RESERVOIR, LOOKING SOUTHEAST - High Mountain Dams in Upalco Unit, Twin Pots Dam, Ashley National Forest, 10.1 miles North of Mountain Home, Mountain Home, Duchesne County, UT

404

Discover World Religions LOCALLYThe Twin Cities encompasses significant religious  

E-print Network

Discover World Religions LOCALLYThe Twin Cities encompasses significant religious diversity at the varieties of religious practice in the Twin Cities as a way of exploring world religions. We would look

Amin, S. Massoud

405

Genetic modelling of dizygotic twinning in pedigrees of spontaneous dizygotic twins  

SciTech Connect

The inheritance of spontaneous dizygotic (DZ) twinning was investigated in 1,422 three-generation pedigrees ascertained through mothers of spontaneous DZ proband twins. DZ twinning was modelled as a trait expressed only in women. The penetrance was modelled first as a parity independent and secondly as parity dependent. The observed frequencies of maternal and paternal grandmothers with DZ twins differed significantly from the expectations under an X-linked mode of inheritance. Complex segregation analysis showed that the parity-independent phenotype of {open_quotes}having DZ twins{close_quotes} was consistent with an autosomal monogenic dominant model, with a gene frequency of 0.035 and a female-specific lifetime penetrance of 0.10. Recessive, polygenic, and sporadic models were rejected. The autosomal dominant model revealed a strong robustness against a changing population prevalence and the loss of information due to the presence of same-sexed twin pairs of unknown zygosity. When DZ twinning was modelled as a parity dependent trait, the data were compatible with an autosomal dominant model with a gene frequency of 0.306 and a penetrance of 0.03 per birth for female gene carriers. 19 refs., 5 tabs.

Meulemans, W.J.; Derom, C.A.; Derom, R.M. [Univ. of Leuven (Belgium)] [and others] [Univ. of Leuven (Belgium); and others

1996-01-22

406

Role of adjunctive medical therapy in the fetoscopic surgical treatment of twin-twin transfusion syndrome.  

PubMed

The underlying etiology of twin-twin transfusion syndrome (TTTS) is unknown, but our growing understanding of the cardiovascular features of TTTS suggests this may be a disease that could respond to transplacental medical therapy. Adjunctive medical therapy in TTTS with the calcium channel blocker nifedipine has been shown to improve recipient survival while having no effect on the donor. There is no significant difference in recipient survival from postoperative day 5 to birth suggesting that the survival benefit is confined to the effects of nifedipine in the perioperative period. Also, there is no significant effect of nifedipine on gestational age at delivery suggesting the survival benefit was unrelated to the tocolytic effects of nifedipine and more likely a result of hemodynamic effects in the recipient twins' cardiovascular system during the perioperative period. TTTS remains poorly understood but there appears to be good evidence suggesting twin-twin hypertensive cardiomyopathy is a large component of the pathophysiology in recipient twins. The initial findings of nifedipine's effectiveness as a targeted medical therapy to address TTTS cardiomyopathy and improve survival of recipient twins opens the door for further research for adjunctive medical therapies in TTTS. PMID:25077476

Zaretsky, Michael V; Somme, Stig; Crombleholme, Timothy M

2014-09-01

407

A core gut microbiome in obese and lean twins.  

PubMed

The human distal gut harbours a vast ensemble of microbes (the microbiota) that provide important metabolic capabilities, including the ability to extract energy from otherwise indigestible dietary polysaccharides. Studies of a few unrelated, healthy adults have revealed substantial diversity in their gut communities, as measured by sequencing 16S rRNA genes, yet how this diversity relates to function and to the rest of the genes in the collective genomes of the microbiota (the gut microbiome) remains obscure. Studies of lean and obese mice suggest that the gut microbiota affects energy balance by influencing the efficiency of calorie harvest from the diet, and how this harvested energy is used and stored. Here we characterize the faecal microbial communities of adult female monozygotic and dizygotic twin pairs concordant for leanness or obesity, and their mothers, to address how host genotype, environmental exposure and host adiposity influence the gut microbiome. Analysis of 154 individuals yielded 9,920 near full-length and 1,937,461 partial bacterial 16S rRNA sequences, plus 2.14 gigabases from their microbiomes. The results reveal that the human gut microbiome is shared among family members, but that each person's gut microbial community varies in the specific bacterial lineages present, with a comparable degree of co-variation between adult monozygotic and dizygotic twin pairs. However, there was a wide array of shared microbial genes among sampled individuals, comprising an extensive, identifiable 'core microbiome' at the gene, rather than at the organismal lineage, level. Obesity is associated with phylum-level changes in the microbiota, reduced bacterial diversity and altered representation of bacterial genes and metabolic pathways. These results demonstrate that a diversity of organismal assemblages can nonetheless yield a core microbiome at a functional level, and that deviations from this core are associated with different physiological states (obese compared with lean). PMID:19043404

Turnbaugh, Peter J; Hamady, Micah; Yatsunenko, Tanya; Cantarel, Brandi L; Duncan, Alexis; Ley, Ruth E; Sogin, Mitchell L; Jones, William J; Roe, Bruce A; Affourtit, Jason P; Egholm, Michael; Henrissat, Bernard; Heath, Andrew C; Knight, Rob; Gordon, Jeffrey I

2009-01-22

408

Sororin is a master regulator of sister chromatid cohesion and separation  

PubMed Central

The maintenance of sister chromatid cohesion from S phase to the onset of anaphase relies on a small but evolutionarily conserved protein called Sororin. Sororin is a phosphoprotein and its dynamic localization and function are regulated by protein kinases, such as Cdk1/cyclin B and Erk2. The association of Sororin with chromatin requires cohesin to be preloaded to chromatin and modification of Smc3 during DNA replication. Sororin antagonizes the function of Wapl in cohesin releasing from S to G2 phase and promotes cohesin release from sister chromatid arms in prophase via interaction with Plk1. This review focuses on progress of the identification and regulation of Sororin during cell cycle; role of post-translational modification on Sororin function; role of Sororin in the maintenance and resolution of sister chromatid cohesion; and finally discusses Sororin’s emerging role in cancer and the potential issues that need be addressed in the future. PMID:22580470

Zhang, Nenggang; Pati, Debananda

2012-01-01

409

Osteological evidence for sister group relationship between pseudo-toothed birds (Aves: Odontopterygiformes) and waterfowls (Anseriformes)  

NASA Astrophysics Data System (ADS)

The phylogenetic affinities of the extinct pseudo-toothed birds have remained controversial. Some authors noted that they resemble both pelicans and allies (Pelecaniformes) and tube-nosed birds (Procellariiformes), but assigned them to a distinct taxon, the Odontopterygiformes. In most recent studies, the pseudo-toothed birds are referred to the family Pelagornithidae inside the Pelecaniformes. Here, I perform a cladistic analysis with five taxa of the pseudo-toothed birds including two undescribed new species from the Early Tertiary of Morocco. The present hypothesis strongly supports a sister group relationship of pseudo-toothed birds (Odontopterygiformes) and waterfowls (Anseriformes). The Odontoanserae (Odontopterygiformes plus Anseriformes) are the sister group of Neoaves. The placement of the landfowls (Galliformes) as the sister taxon of all other neognathous birds does not support the consensus view that the Galloanserae (Galliformes plus Anseriformes) are monophyletic.

Bourdon, Estelle

2005-12-01

410

Twin and Mirror Symmetries from Presymmetry  

E-print Network

We argue that presymmetry, a hidden predynamical electroweak quark-lepton symmetry that explains the fractional charges and triplication of families, must be extended beyond the Standard Model as to have a residual presymmetry that embraces partner particles and includes the strong sector, so accounting for the twin or mirror partners proposed to alleviate the naturalness problem of the weak scale. It leads to the full duplication of fermions and gauge bosons of the Standard Model independently of the ultraviolet completion of the theory, even if the Higgs particle is discarded by experiment, which adds robustness to twin and mirror symmetries. The established connection is so strongly motivated that the search for twin or mirror matter becomes the possible test of presymmetry. If the physics beyond the Standard Model repairs its left-right asymmetry, mirror symmetry should be the one realized in nature.

Ernesto A. Matute

2011-11-11

411

Coupling of twin rectangular supersonic jets  

E-print Network

;Y)-plane (see gure 1 for coordinates), for single and coupled twin jets. The (X;Y)-plane was located at z=h = 3. The data shown in Coupling of twin rectangular supersonic jets 133 (a) (b) (c) (d) ?10 ?5 0 5 10 8 7 6 5 4 3 z h ?10 ?5 0 5 10 8 7 6 5 4 3 ?10 ?5 0... further. The data of gures 14 and 15 will be used to examine how the jets choose the Coupling of twin rectangular supersonic jets 139 0 8 4 ?4 ?8 (a) 0 4 8 12 16 y h (c) 0481216 0 8 4 ?4 ?8 (b) 0 4 8 12 16 y h (d) 0481216 x/h x/h Figure 13. Comparison...

Raman, G.; Taghavi, Ray

1998-01-01

412

Stability of ideal fcc twin boundaries  

NASA Astrophysics Data System (ADS)

Ideas from continuum mechanics are used to derive an elastic stability inequality for a boundary between two different materials under quasi-static, homogeneous conditions. The terms in this inequality are interpreted for the case of an ideal twinning plane between two variants of a face-centered cubic material. High quality potentials for Ni and Cu are used in molecular dynamics calculations to calibrate relevant energies and displacements near the twinning plane. It is found that in comparison with direct molecular dynamics calculations the inequality predicts the critical stress that initiates movement of the twinning plane in Ni within 1.9% and within 1.3% for Cu. Although the predicted and calculated critical stresses are only upper bounds for the more realistic case of an imperfect boundary, the calculations give considerable insight into the interplay of energies that lead to boundary motion.

Wright, T. W.; Daphalapurkar, N. P.; Ramesh, K. T.

2014-12-01

413

Twin and Mirror Symmetries from Presymmetry  

NASA Astrophysics Data System (ADS)

We argue that presymmetry, a hidden predynamical electroweak quark-lepton symmetry that explains the fractional charges and triplication of families, must be extended beyond the Standard Model as to have a residual presymmetry that embraces partner particles and includes the strong sector, so accounting for the twin or mirror partners proposed to alleviate the naturalness problem of the weak scale. It leads to the full duplication of fermions and gauge bosons of the Standard Model independently of the ultraviolet completion of the theory, even if the Higgs particle is discarded by experiment, which adds robustness to twin and mirror symmetries. The established connection is so strongly motivated that the search for twin or mirror matter becomes the possible test of presymmetry. If the physics beyond the Standard Model repairs its left-right asymmetry, mirror symmetry should be the one realized in nature.

Matute, Ernesto A.

414

The twin paradox in the presence of gravity  

E-print Network

Conventional wisdom, based on kinematic (flat-space) intuition, tell us that a static twin is aging faster than his traveling twin brother. However, such a situation could be exactly inverted if the two twins are embedded in an external gravitational field, and if the (dynamical) distortion of the space-time geometry, due to gravity, is strong enough to compensate the kinematic effect of the relative twin motion.

M. Gasperini

2014-09-05

415

Generation of deformation twins in nanocrystalline metals: Theoretical model  

SciTech Connect

A theoretical model is suggested that describes the generation of deformation twins at grain boundaries in nanocrystalline metals. Within the model, a thick twin lamella in a nanoscale grain is generated due to stress-driven emission of twinning dislocations from a grain boundary. The lamella consists of overlapping stacking faults. The results account for experimental data on observation of deformation twins in nanocrystalline Al and Cu reported in the literature.

Gutkin, M. Yu.; Ovid'ko, I. A.; Skiba, N. V. [Institute of Problems of Mechanical Engineering, Russian Academy of Sciences, Bolshoj 61, Vasil. Ostrov, St. Petersburg 199178 (Russian Federation)

2006-11-01

416

Twin-roll strip casting of magnesium alloys in China  

Microsoft Academic Search

The development status of twin-roll strip casting for magnesium alloys in China was summarized as well as the new progress when several kinds of twin-roll strip casting technologies were developed and used. Horizontal twin-roll casting (HTRC) of magnesium alloys has attracted much attention and has been industrialized in China. Vertical twin roll casting (VTRC) of the magnesium alloys can reach

Pei-dao DING; Fu-sheng PAN; Bin JIANG; Jian WANG; Hua-lun LI; Jiang-cai WU; Yue-wang XU; Yu WEN

2008-01-01

417

The twin paradox in the presence of gravity  

NASA Astrophysics Data System (ADS)

Conventional wisdom, based on kinematic (flat-space) intuition, tell us that a static twin is aging faster than his traveling twin brother. However, such a situation could be exactly inverted if the two twins are embedded in an external gravitational field, and if the (dynamical) distortion of the spacetime geometry, due to gravity, is strong enough to compensate the kinematic effect of the relative twin motion.

Gasperini, M.

2014-09-01

418

RecA bundles mediate homology pairing between distant sisters during DNA break repair  

PubMed Central

DNA double-strand break (DSB) repair by homologous recombination (HR) has evolved to maintain genetic integrity in all organisms1. Although many reactions that occur during HR are known1-3, it is unclear where, when and how they occur in cells is lacking. Here, by using conventional and super-resolution microscopy we describe the progression of DSB repair in live Escherichia coli. Specifically, we investigate whether HR can occur efficiently between distant sister loci that have segregated to opposite halves of an E. coli cell. We show that a site-specific DSB in one sister can be repaired efficiently using distant sister homology. After RecBCD processing of the DSB, RecA is recruited to the cut locus, where it nucleates into a bundle that contains many more RecA molecules than can associate with the two ssDNA regions that form at the DSB. Mature bundles extend along the cell long axis in the space between the bulk nucleoid and the inner membrane. Bundle formation is followed by pairing in which the two ends of the cut locus relocate at the periphery of the nucleoid and together move rapidly towards the homology of the uncut sister. After sister locus pairing, RecA bundles disassemble and proteins that act late in HR are recruited to give viable recombinants 1-2 generation time equivalents after formation of the initial DSB. Mutated RecA proteins that do not form bundles are defective in sister pairing and in DSB-induced repair. The work reveals an unanticipated role of RecA bundles in channeling the movement of the DNA DSB ends, thereby facilitating the long-range homology search that occurs before the strand invasion and transfer reactions. PMID:24362571

Lesterlin, Christian; Ball, Graeme; Schermelleh, Lothar; Sherratt, David J.

2014-01-01

419

The twin paradox in a cosmological context  

E-print Network

Recently Abramowicz and Bajtlik [ArXiv: 0905.2428 (2009)] have studied the twin paradox in Schwarzschild spacetime. Considering circular motion they showed that the twin with a non-vanishing 4-acceleration is older than his brother at the reunion and argued that in spaces that are asymptotically Minkowskian there exists an absolute standard of rest determining which twin is oldest at the reunion. Here we show that with vertical motion in Schwarzschild spacetime the result is opposite: The twin with a non-vanishing 4-acceleration is younger. We also deduce the existence of a new relativistic time effect, that there is either a time dilation or an increased rate of time associated with a clock moving in a rotating frame. This is in fact a first order effect in the velocity of the clock, and must be taken into account if the situation presented by Abramowicz and Bajtlik is described from the rotating rest frame of one of the twins. Our analysis shows that this effect has a Machian character since the rotating state of a frame depends upon the motion of the cosmic matter due to the inertial dragging it causes. We argue that a consistent formulation and resolution of the twin paradox makes use of the general principle of relativity and requires the introduction of an extended model of the Minkowski spacetime. In the extended model Minkowski spacetime is supplied with a cosmic shell of matter with radius equal to its own Schwarzschild radius, so that there is perfect inertial dragging inside the shell.

O. Gron; S. Braeck

2011-09-20

420

Hirschsprung's disease in twin to twin transfusion syndrome: A case report.  

PubMed

Twin to twin transfusion syndrome (TTTS) is caused by aberrant vascular connections between infant twins and results in high morbidity and mortality in the perinatal period. In donor infants with TTTS and symptoms of intestinal obstruction, small-bowel lesions have been reported in most cases. We report on a 33(+6) gestational wk donor infant with TTTS who had intermittent obstructive episodes, including delayed meconium passage and colonic dilatation on abdominal X-ray. The diagnosis of Hirschsprung's disease was based on a lateral pelvic film with a reversed rectosigmoid ratio. A subsequent barium colon study and rectal suction biopsy indicated a short segment aganglionosis of the colon. PMID:25516683

Park, Hye Won; Cho, Min Jeng; Kim, Wook Youn; Kwak, Byung Ok; Kim, Min Hee

2014-12-14

421

Needle twins and right-angled twins in minerals: comparison between experiment and theory  

USGS Publications Warehouse

Transformation twinning in minerals forms isolated twin walls, intesecting walls with corner junctions, and wedge-shaped twins as elements of hierarchical patterns. When cut perpendicular to the twin walls, the twins have characteristic shapes, right-angled and needle-shaped wall traces, which can be observed by transmission electron microscopy or by optical microscopy. Theoretical geometries of wall shapes recently derived for strain-related systems should hold for most displacive and order-disorder type phase transitions: 1) right-angled twins show curved junctions; 2) needle-shaped twins contain flat wall segments near the needle tip if the elastic behaviour of the mineral is dominated by its anisotroyp; 3) additional bending forces and pinning effects lead to curved walls near the junction that make the needle tip appear more blunt. Bent right-angled twins were analyzed in Gd2(MoO4)3. Linear needle tips were found in WO3, [N(CH3)4]2.ZnBr4 CrAl, BiVO4, GdBa2Cu3O7, and PbZrO. Parabolic tips occur in K2Ba(NO2)4, and GeTe whereas exponential curvatures appear in BaTiO3, KSCN, Pb3(PO4)2, CaTiO3, alkali feldspars, YBa2Cu3O7, and MnAl. The size and shape of the twin microstructure relates to its formation during the phase transition and the subsequent annealing history. The mobility of the twin walls after formation depends not only on the thermal activation but also on the structure of the wall, which may be pinned to impurities on a favorable structural site. Depinnign energies are often large compared with thermal energies for diffusion. This leads to kinetic time scales for twin coarsening that are comparable to geological time scales. Therefore, transformation twins that exhibit needle domains not only indicate that the mineral underwent a structural phase transition but also contain information about its subsequent geological history.

Salje, E.K.H.; Buckley, A.; Van Tendeloo, G.; Ishibashi, Y.; Nord, G.L., Jr.

1998-01-01

422

Low-noise macroscopic twin beams  

E-print Network

Applying a multiphoton-subtraction technique to two-color macroscopic squeezed vacuum state of light generated via high-gain parametric down conversion we conditionally prepare a new state of light: bright multi-mode low-noise twin beams. The obtained results demonstrate up to 8-fold suppression of noise in each beam while preserving and even moderately improving the nonclassical photon number correlations between the beams. The prepared low-noise macroscopic state, containing up to 2000 photons per mode, is not among the states achievable through nonlinear optical processes. The proposed technique substantially improves the usefulness of twin beams for quantum technologies.

Timur Sh. Iskhakov; Vladyslav C. Usenko; Radim Filip; Maria V. Chekhova; Gerd Leuchs

2014-08-27

423

Twin inequality for fully contextual quantum correlations  

E-print Network

Quantum mechanics exhibits a very peculiar form of contextuality. Identifying and connecting the simplest scenarios in which more general theories can or cannot be more contextual than quantum mechanics is a fundamental step in the quest for the principle that singles out quantum contextuality. The former scenario corresponds to the Klyachko-Can-Binicioglu-Shumovsky (KCBS) inequality. Here we show that there is a simple tight inequality, twin to the KCBS, for which quantum contextuality cannot be outperformed. In a sense, this twin inequality is the simplest tool for recognizing fully contextual quantum correlations.

Adan Cabello

2013-02-15

424

Epicyclic Twin-Helix Ionization Cooling Simulations  

SciTech Connect

Parametric-resonance Ionization Cooling (PIC) is proposed as the final 6D cooling stage of a highluminosity muon collider. For the implementation of PIC, we earlier developed an epicyclic twin-helix channel with correlated behavior of the horizontal and vertical betatron motions and dispersion. We now insert absorber plates with short energy-recovering units located next to them at the appropriate locations in the twin-helix channel. We first demonstrate conventional ionization cooling in such a system with the optics uncorrelated. We then adjust the correlated optics state and induce a parametric resonance to study ionization cooling under the resonant condition.

Vasiliy Morozov, Yaroslav Derbenev, A. Afanaciev, R.P. Johnson

2011-04-01

425

Role of twinning in plastic deformation  

SciTech Connect

A new concept of the structure of yttrium-aluminum garnet (Y{sub 3}Al{sub 5}O{sub 12}) has demonstrated the possibility of forming inversion twins in the (111) plane. The twinning processes are shown to be responsible for stress relaxation during the growth and plastic deformation of Y{sub 3}Al{sub 5}O{sub 12} single crystals. This way of stress relaxation can be used to describe the plastic deformation of other crystals, at least cubic ones.

Akchurin, M. Sh., E-mail: akchurin@ns.crys.ras.ru; Zakalyukin, R. M.; Kaminsky, A. A.; Kupenko, I. I. [Russian Academy of Sciences, Shubnikov Institute of Crystallography (Russian Federation)

2010-07-15

426

Synergistic convergence and split pons in horizontal gaze palsy and progressive scoliosis in two sisters.  

PubMed

Synergistic convergence is an ocular motor anomaly where on attempted abduction or on attempted horizontal gaze, both the eyes converge. It has been related to peripheral causes such as congenital fibrosis of extraocular muscles (CFEOM), congenital cranial dysinnervation syndrome, ocular misinnervation or rarely central causes like horizontal gaze palsy with progressive scoliosis, brain stem dysplasia. We hereby report the occurrence of synergistic convergence in two sisters. Both of them also had kyphoscoliosis. Magnetic resonance imaging (MRI) brain and spine in both the patients showed signs of brain stem dysplasia (split pons sign) differing in degree (younger sister had more marked changes). PMID:21350292

Jain, Nitin R; Jethani, Jitendra; Narendran, Kalpana; Kanth, L

2011-01-01

427

Synergistic convergence and split pons in horizontal gaze palsy and progressive scoliosis in two sisters  

PubMed Central

Synergistic convergence is an ocular motor anomaly where on attempted abduction or on attempted horizontal gaze, both the eyes converge. It has been related to peripheral causes such as congenital fibrosis of extraocular muscles (CFEOM), congenital cranial dysinnervation syndrome, ocular misinnervation or rarely central causes like horizontal gaze palsy with progressive scoliosis, brain stem dysplasia. We hereby report the occurrence of synergistic convergence in two sisters. Both of them also had kyphoscoliosis. Magnetic resonance imaging (MRI) brain and spine in both the patients showed signs of brain stem dysplasia (split pons sign) differing in degree (younger sister had more marked changes). PMID:21350292

Jain, Nitin R; Jethani, Jitendra; Narendran, Kalpana; Kanth, L

2011-01-01

428

Testing structural equation models for twin data using LISREL  

Microsoft Academic Search

Simple genetic models can be fitted to twin data using software packages such as LISREL (Jöreskog and Sörbom, 1986a). After discussion of data preparation and routine checks on possible violation of assumptions of the twin method, we illustrate univariate, bivariate, and multivariate genetic models which can be tested in cross-sectional twin data using LISREL. These include models for cohort or

A. C. Heath; M. C. Neale; J. K. Hewitt; L. J. Eaves; D. W. Fulker

1989-01-01

429

Brain size, head size, and intelligence quotient in monozygotic twins  

E-print Network

Brain size, head size, and intelligence quotient in monozygotic twins M.J. Tramo, MD; W.C. Loftus-Many studies of monozygotic (MZ)twins have revealed evidence of genetic influences on intellectual functions in MZ twins and their relationship to head size and intelligence quotient (IQ).ANOVA were carried out

Gazzaniga, Michael

430

Self-Replicating Twins in Nanowires Zaoshi Yuan,  

E-print Network

Self-Replicating Twins in Nanowires Zaoshi Yuan, and Aiichiro Nakano*, Collaboratory for Advanced-dynamics simulations validated with quantum-mechanical calculations, we predict that (111) twin planes in a [111-replication mechanism that continuously generates a twin superlattice in a nanowire during growth. We demonstrate signi

Southern California, University of

431

Twins of rayless graphs Anthony Bonato Henning Bruhn Reinhard Diestel  

E-print Network

Twins of rayless graphs Anthony Bonato Henning Bruhn Reinhard Diestel Philipp Spr¨ussel Abstract Two non-isomorphic graphs are twins if each is isomorphic to a sub- graph of the other. We prove that a rayless graph has either infinitely many twins or none. 1 Introduction Up to isomorphism, the subgraph

Diestel, Reinhard

432

Twin Balance Laws for Bodies Undergoing Structured Motions  

E-print Network

Twin Balance Laws for Bodies Undergoing Structured Motions David R. Owen Department of Mathematical.2 Postulate of invariance of the power . . . . . . . . . . . . . . . . . . . . . . 15 5 Twin balance laws 15 will be called a pair of \\twin balance laws" for reasons that will become apparent in what follows. Speci#12

433

Sensitivity and Consistency of Maternal Writing Mediation to Twin Kindergartners  

ERIC Educational Resources Information Center

This study investigated whether mothers are responsive to their children's literacy level, thus employing different writing mediation styles with each twin according to the child's level, or whether they possess a consistent style employed with both twins. The sample included 28 sets of twin kindergartners (56 children, M age = 68.89 months) and…

Aram, Dorit

2007-01-01

434

Phenotypically Concordant and Discordant Monozygotic Twins Display Different  

E-print Network

to environmental factors. Examples of genetic and, more recently, epigenetic differences between MZ twins haveREPORT Phenotypically Concordant and Discordant Monozygotic Twins Display Different DNA Copy, is an understudied aspect of genome biology. Any differences in the genetic makeup between twins derived from

Crasto, Chiquito

435

Healthy Eating with Diabetes Video  

MedlinePLUS Videos and Cool Tools

... Eating with Diabetes Video Healthy Eating with Diabetes Video Making changes in the way you eat can ... Eating with Diabetes Transcript Healthy Eating with Diabetes Video (MP4) Keywords: self-management , healthy eating , National Diabetes ...

436

Conditional Probability and Independence 1. Twins make up a small fraction of the human population. Identical (monogygotic) twins make up 8%  

E-print Network

Conditional Probability and Independence Worksheet 1. Twins make up a small fraction of the human population. Identical (monogygotic) twins make up 8% of all twins. Identical twins always have the same sex. The other 92% of twins are called dizygotic or fraternal. In a family having two children who

Watkins, Joseph C.

437

Staying Healthy with Diabetes  

MedlinePLUS

... Public Health Resource Share Compartir Staying Healthy with Diabetes On this Page What routine medical examinations and ... examinations and tests are needed for people with diabetes? Your doctors should— Measure your blood pressure at ...

438

Eating Healthy Ethnic Food  

MedlinePLUS

... and terms to look for when making your selection: Chinese Zheng (steamed) Jum (poached) Kao (roasted) Shao ( ... Pocket Guide to Eating Healthy on the Go features tips on ordering at a variety of American ...

439

Tips for Healthy Living  

MedlinePLUS

... message, please visit this page: About CDC.gov . Hemochromatosis (Iron Storage Disease) National Center Homepage Share Compartir Tips for Healthy Living If you have hemochromatosis, there is much you can do to make ...

440

Healthy Living after Stroke  

MedlinePLUS

Healthy Living After Stroke Nutrition Good nutrition is one way to reduce your risk of having another stroke. Find tips for shopping, how ... you reduce your risk of stroke. Subscribe to Stroke Connection Get quarterly digital issues plus our monthly ...

441

Healthy Air Outdoors  

MedlinePLUS

... even threaten life itself. Protecting Your Health Outdoor air pollution threatens the lives and health of millions of ... complex challenges of global warming and energy use, air pollution remains a widespread problem. » More Fighting for Healthy ...

442

Healthy grocery shopping  

MedlinePLUS

... Choose healthy breads, cereals, and pasta, such as: Whole-grain breads and rolls, such as whole-wheat, pumpernickel, ... of fiber per serving. Whole-wheat or other whole-grain pasta Always buy real foods. Look for 100% ...

443

Healthy Aging -- Sexual Health  

MedlinePLUS

... Healthy Aging This information in Spanish ( en espańol ) Sexual health More information on sexual health Many older women ... Protecting yourself Return to top More information on Sexual health Read more from womenshealth.gov Sexually Transmitted Infections ...

444

Tips for Healthy Voices  

MedlinePLUS

... is essential to maintaining a healthy voice. The vocal cords vibrate extremely fast even with the most ... water consumption optimizes the throat?s mucous production, aiding vocal cord lubrication. To maintain sufficient hydration avoid or ...

445

Healthy Roads Media  

MedlinePLUS

... support for Healthy Roads Media to disseminate free multilingual resources via the web has come to an ... by NLM-SIS to address the need for multilingual health information. Please contact the NLM-SIS with ...

446

Late Language Emergence in 24-Month-Old Twins: Heritable and Increased Risk for Late Language Emergence in Twins  

ERIC Educational Resources Information Center

Purpose: This study investigated the etiology of late language emergence (LLE) in 24-month-old twins, considering possible twinning, zygosity, gender, and heritability effects for vocabulary and grammar phenotypes. Method: A population-based sample of 473 twin pairs participated. Multilevel modeling estimated means and variances of vocabulary and…

Rice, Mabel L.; Zubrick, Stephen R.; Taylor, Catherine L.; Gayán, Javier; Bontempo, Daniel E.

2014-01-01

447

194 Twin Research and Human Genetics Volume 9 Number 2 pp. 194197 Accurate determination of same-sex twin zygosity  

E-print Network

194 Twin Research and Human Genetics Volume 9 Number 2 pp. 194­197 Accurate determination of same-sex twin zygosity is important for medical, scientific and personal reasons. Determination may be based proba- bilities of correctly concluding a twin pair is monozygotic, given they share the same genotypes

Nyholt, Dale R.

448

Stromswold & Rifkin, Language Acquisition by MZ & DZ SLI Twins (SRCLD, 1996) 1 Language Acquisition by Identical vs. Fraternal SLI Twins*  

E-print Network

Stromswold & Rifkin, Language Acquisition by MZ & DZ SLI Twins (SRCLD, 1996) 1 Language Acquisition by Identical vs. Fraternal SLI Twins* Karin Stromswold & Jay I. Rifkin Dept. of Psychology & Ctr. for Cognitive acquisition by sets of identical (monozygotic, MZ) and fraternal (dizygotic, DZ) twins with specific language

Stromswold, Karin

449

Twin nucleation and migration in FeCr single crystals  

SciTech Connect

Tension and compression experiments were conducted on body-centered cubic Fe -47.8 at pct. Cr single crystals. The critical resolved shear stress (CRSS) magnitudes for slip nucleation, twin nucleation and twin migration were established. We show that the nucleation of slip occurs at a CRSS of about 88 MPa, while twinning nucleates at a CRSS of about 191 MPa with an associated load drop. Following twin nucleation, twin migration proceeds at a CRSS that is lower than the initiation stress ( Almost-Equal-To 114-153 MPa). The experimental results of the nucleation stresses indicate that the Schmid law holds to a first approximation for the slip and twin nucleation cases, but to a lesser extent for twin migration particularly when considerable slip strains preceded twinning. The CRSSs were determined experimentally using digital image correlation (DIC) in conjunction with electron back scattering diffraction (EBSD). The DIC measurements enabled pinpointing the precise stress on the stress-strain curves where twins or slip were activated. The crystal orientations were obtained using EBSD and used to determine the activated twin and slip systems through trace analysis. - Highlights: Black-Right-Pointing-Pointer Digital image correlation allows to capture slip/twin initiation for bcc FeCr. Black-Right-Pointing-Pointer Crystal orientations from EBSD allow slip/twin system indexing. Black-Right-Pointing-Pointer Nucleation of slip always precedes twinning. Black-Right-Pointing-Pointer Twin growth is sustained with a lower stress than required for nucleation. Black-Right-Pointing-Pointer Twin-slip interactions provide high hardening at the onset of plasticity.

Patriarca, L. [Politecnico di Milano, Department of Mechanical Engineering, Via La Masa 34, I-20156 Milano (Italy)] [Politecnico di Milano, Department of Mechanical Engineering, Via La Masa 34, I-20156 Milano (Italy); Abuzaid, Wael [Department of Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, 1206 W. Green St., Urbana, IL 61801 (United States)] [Department of Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, 1206 W. Green St., Urbana, IL 61801 (United States); Sehitoglu, Huseyin, E-mail: huseyin@illinois.edu [Department of Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, 1206 W. Green St., Urbana, IL 61801 (United States)] [Department of Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, 1206 W. Green St., Urbana, IL 61801 (United States); Maier, Hans J. [Lehrstuhl fuer Werkstoffkunde (Materials Science), University of Paderborn, 33095 Paderborn (Germany)] [Lehrstuhl fuer Werkstoffkunde (Materials Science), University of Paderborn, 33095 Paderborn (Germany); Chumlyakov, Y. [Physics of Plasticity and Strength of Materials Laboratory, Siberian Physical and Technical Institute, 634050 Tomsk (Russian Federation)] [Physics of Plasticity and Strength of Materials Laboratory, Siberian Physical and Technical Institute, 634050 Tomsk (Russian Federation)

2013-01-15

450

Vermian Hypoplasia and Arrested Cerebral Myelination in Two Sisters: Variant of Joubert's Syndrome or a New Syndrome?  

Microsoft Academic Search

Two adult sisters have vermian hypoplasia, ataxia, nystagmus, pontine divergence insufficiency, and mild to moderate intellectual disability, with an arrest of cerebral myelination resembling the pattern of a 4-month-old infant. Other abnormalities include high myopia, optic nerve hypoplasia, decreased bone density, hypoplasia of the secondary teeth, and amenorrhea. We did not find matching patients described in the literature. The sisters

William DeMyer; Alberto Espay; Laurence Walsh; Susan Benes; Mary Edwards-Brown

2003-01-01

451

Nanoscale twinning-induced elastic strengthening in silicon carbide nanowires  

SciTech Connect

Compressibility of periodically twinned silicon carbide nanowires is studied using in situ high pressure X-ray diffraction. Twinned SiC nanowires displayed a bulk modulus of 316 GPa, {approx}20-40% higher than previously reported values for SiC of other morphologies. This finding provides direct evidence of a significant effect of twinned structures on the elastic properties of SiC on the nano scale and supports previous molecular dynamics simulations of twin boundary/stacking fault-induced strengthening. Both experiments and simulations indicate that nanoscale twinning is an effective pathway by which to tailor the mechanical properties of nanostructures.

Lin, Z.J.; Wang, Lin; Zhang, Jianzhong; Guo, Xiang-Yun; Yang, Wenge; Mao, Ho-Kwang; Zhao, Yusheng (Inst. Coal Chem.); (CIW); (LANL)

2010-10-22

452

The continuing value of twin studies in the omics era.  

PubMed

The classical twin study has been a powerful heuristic in biomedical, psychiatric and behavioural research for decades. Twin registries worldwide have collected biological material and longitudinal phenotypic data on tens of thousands of twins, providing a valuable resource for studying complex phenotypes and their underlying biology. In this Review, we consider the continuing value of twin studies in the current era of molecular genetic studies. We conclude that classical twin methods combined with novel technologies represent a powerful approach towards identifying and understanding the molecular pathways that underlie complex traits. PMID:22847273

van Dongen, Jenny; Slagboom, P Eline; Draisma, Harmen H M; Martin, Nicholas G; Boomsma, Dorret I

2012-09-01

453

The twin paradox and Mach's principle  

E-print Network

The problem of absolute motion in the context of the twin paradox is discussed. It is shown that the various versions of the clock paradox feature some aspects which Mach might have been appreciated. However, the ultimate cause of the behavior of the clocks must be attributed to the autonomous status of spacetime, thereby proving the relational program advocated by Mach as impracticable.

Herbert I. M. Lichtenegger; Lorenzo Iorio

2011-11-23

454

Prediction of twin-arginine signal peptides  

Microsoft Academic Search

Background: Proteins carrying twin-arginine (Tat) signal peptides are exported into the periplasmic compartment or extracellular environment independently of the classical Sec- dependent translocation pathway. To complement other methods for classical signal peptide prediction we here present a publicly available method, TatP, for prediction of bacterial Tat signal peptides. Results: We have retrieved sequence data for Tat substrates in order to

Jannick Dyrlřv Bendtsen; Henrik Nielsen; David Widdick; Tracy Palmer; Sřren Brunak

2005-01-01

455

A twin approach to unraveling epigenetics  

PubMed Central

The regulation of gene expression plays a pivotal role in complex phenotypes, and epigenetic mechanisms such as DNA methylation are essential to this process. The availability of next-generation sequencing technologies allows us to study epigenetic variation at an unprecedented level of resolution. Even so, our understanding of the underlying sources of epigenetic variability remains limited. Twin studies have played an essential role in estimating phenotypic heritability, and these now offer an opportunity to study epigenetic variation as a dynamic quantitative trait. High monozygotic twin discordance rates for common diseases suggest that unexplained environmental or epigenetic factors could be involved. Recent genome-wide epigenetic studies in disease-discordant monozygotic twins emphasize the power of this design to successfully identify epigenetic changes associated with complex traits. We describe how large-scale epigenetic studies of twins can improve our understanding of how genetic, environmental and stochastic factors impact upon epigenetics, and how such studies can provide a comprehensive understanding of how epigenetic variation affects complex traits. PMID:21257220

Bell, Jordana T.; Spector, Tim D.

2011-01-01

456

Gene-Environment Interplay in Twin Models.  

PubMed

In this article, we respond to Shultziner's critique that argues that identical twins are more alike not because of genetic similarity, but because they select into more similar environments and respond to stimuli in comparable ways, and that these effects bias twin model estimates to such an extent that they are invalid. The essay further argues that the theory and methods that undergird twin models, as well as the empirical studies which rely upon them, are unaware of these potential biases. We correct this and other misunderstandings in the essay and find that gene-environment (GE) interplay is a well-articulated concept in behavior genetics and political science, operationalized as gene-environment correlation and gene-environment interaction. Both are incorporated into interpretations of the classical twin design (CTD) and estimated in numerous empirical studies through extensions of the CTD. We then conduct simulations to quantify the influence of GE interplay on estimates from the CTD. Due to the criticism's mischaracterization of the CTD and GE interplay, combined with the absence of any empirical evidence to counter what is presented in the extant literature and this article, we conclude that the critique does not enhance our understanding of the processes that drive political traits, genetic or otherwise. PMID:24808718

Verhulst, Brad; Hatemi, Peter K

2013-07-01

457

The twin spot generator for differential Drosophila  

E-print Network

on the basis of eye color, amplified them and isolated derivative lines (for available TSG lines, seeThe twin spot generator for differential Drosophila lineage analysis Ruth Griffin1, Anne Sustar2 Schubiger2, C-ting Wu3 & Norbert Perrimon3,4 In Drosophila melanogaster, widely used mitotic recombination

Higgins, Darren

458

Osteogenesis imperfecta: cesarean deliveries in identical twins.  

PubMed

Osteogenesis imperfecta is a congenital disorder resulting in multiple fractures and extremely short stature, usually necessitating cesarean delivery. Identical twins with severe osteogenesis imperfecta each of whom underwent a cesarean delivery with different anesthetic modalities are presented. A review of the literature and anesthetic options for cesarean delivery and postoperative analgesia for women with osteogenesis imperfecta are discussed. PMID:25433579

Dinges, E; Ortner, C; Bollag, L; Davies, J; Landau, R

2015-02-01

459

Twin Cities Campus Addiction Studies Postbaccalaureate Certificate  

E-print Network

· · · · · · · Twin Cities Campus Addiction Studies Postbaccalaureate Certificate CCE Addiction: Addiction Studies, Degree and Certificate Programs, 20 Ruttan Hall, 1994 Buford Avenue, St. Paul, MN 55108 (612-624-4000; fax: 612- 625-1511) Email: cceinfo@umn.edu Website: http://www.cce.umn.edu/Addiction

Blanchette, Robert A.

460

Twin troubles--rickets causing myelofibrosis.  

PubMed

Myelofibrosis is an uncommon condition that causes anaemia, failure to thrive and massive splenomegaly. This case report describes migrant Sudanese twins who developed myelofibrosis secondary to severe rickets from a combination of poor diet, inadequate sun exposure, and a breastfeeding mother who wore hijab and was also vitamin D deficient. PMID:17635691

Kamien, Benjamin; Harris, Linda

2007-01-01

461

Superior limbic keratoconjunctivitis in identical twins.  

PubMed

The first two cases of superior limbic keratoconjunctivitis occurring in identical twins are reported. In both cases the symptoms began 16 years ago and have never permanently responded to numerous topical medications or to bilateral resection of the superior bulbar conjunctiva. PMID:1587136

Darrell, R W

1992-05-01

462

Twinning of amphibian embryos by centrifugation  

NASA Technical Reports Server (NTRS)

In the frog Xenopus laevis, the dorsal structures of the embryonic body axis normally derive from the side of the egg opposite the side of sperm entry. However, if the uncleaved egg is inclined at lg or centrifuged in an inclined position, this topographic relationship is overridden: the egg makes its dorsal axial structures according to its orientation in the gravitational/centrifugal field, irrespective of the position of sperm entry. Certain conditions of centrifugation cause eggs to develop into conjoined twins with two sets of axial structures. A detailed analysis of twinning provided some insight into experimental axis orientation. First, as with single-axis embryos, both axes in twins are oriented according to the direction of centrifugation. One axis forms at the centripetal side of the egg and the other forms at the centrifugal side, even when the side of sperm entry is normal to the centrifugal force vector. Second, if eggs are centrifuged to give twins, but are inclined at lg to prevent post-centrifugation endoplasmic redistributions, only single-axis embryos develop. Thus, a second redistribution is required for high-frequency secondary axis formation. This can be accomplished by lg (as in the single centrifugations) or by a second centrifugation directed along the egg's animal-vegetal axis.

Black, S. D.

1984-01-01

463

A Pediatric Twin Study of Brain Morphometry  

ERIC Educational Resources Information Center

Background: Longitudinal pediatric neuroimaging studies have demonstrated increasing volumes of white matter and regionally-specific inverted U shaped developmental trajectories of gray matter volumes during childhood and adolescence. Studies of monozygotic and dyzygotic twins during this developmental period allow exploration of genetic and…

Wallace, Gregory L.; Schmitt, J. Eric; Lenroot, Rhoshel; Viding, Essi; Ordaz, Sarah; Rosenthal, Michael A.; Molloy, Elizabeth A.; Clasen, Liv S.; Kendler, Kenneth S.; Neale, Michael C.; Giedd, Jay N.

2006-01-01

464

Twin Paradox in de Sitter Spacetime  

ERIC Educational Resources Information Center

The "twin paradox" of special relativity offers the possibility of making interstellar flights within a lifetime. For very long journeys with velocities close to the speed of light, however, we have to take into account the expansion of the universe. Inspired by the work of Rindler on hyperbolic motion in curved spacetime, we study the worldline…

Boblest, Sebastian; Muller, Thomas; Wunner, Gunter

2011-01-01

465

A twin approach to unraveling epigenetics.  

PubMed

The regulation of gene expression plays a pivotal role in complex phenotypes, and epigenetic mechanisms such as DNA methylation are essential to this process. The availability of next-generation sequencing technologies allows us to study epigenetic variation at an unprecedented level of resolution. Even so, our understanding of the underlying sources of epigenetic variability remains limited. Twin studies have played an essential role in estimating phenotypic heritability, and these now offer an opportunity to study epigenetic variation as a dynamic quantitative trait. High monozygotic twin discordance rates for common diseases suggest that unexplained environmental or epigenetic factors could be involved. Recent genome-wide epigenetic studies in disease-discordant monozygotic twins emphasize the power of this design to successfully identify epigenetic changes associated with complex traits. We describe how large-scale epigenetic studies of twins can improve our understanding of how genetic, environmental and stochastic factors impact upon epigenetics, and how such studies can provide a comprehensive understanding of how epigenetic variation affects complex traits. PMID:21257220

Bell, Jordana T; Spector, Tim D

2011-03-01

466

Reflectance spectrometry of placental vessels in cases of twin-twin transfusion syndrome: experiments and modeling  

NASA Astrophysics Data System (ADS)

A stochastic photon transport model in multilayer skin tissue combined with reflectance spectroscopy measurements is used to study placental vessels in cases of twin-twin transfusion syndrome (TTTS). TTTS occurs in about 12% of monozygotic (identical) twin pregnancies wherein flow within placental vessels linking the twins together becomes unbalanced, leading to dual mortality. Endoscopic laser ablation can halt the syndrome by occluding the anastomoses connecting the two fetuses. The objective of this study is to develop a technique to determine hemoglobin (Hb) content through spectral analysis of diffuse reflectance spectra of placental vessels to aid in identification of the anastomoses. Previous work by researchers at Brown University has shown that the reflectance spectra of the donor twin and recipient twin are considerably different in the wavelengths for Hb absorbance. This presentation will give preliminary results for a Monte Carlo model adapted to fit the physiology of the placenta that can be used to quantitative determine the Hb levels. The reflectance spectra of the vessels are simulated for different values of Hb as well oxygenation and water concentration with the vessel and placental mass. The preliminary results will be shown to be in good approximation with the prior experimental data. The combination of modeling with spectroscopic measurement will provide a new tool for detailed prenatal study.

Lines, Collin; Kim, Oleg; McMurdy, John; Luks, Francois; Alber, Mark; Crawford, Greg

2013-03-01

467

University of Washington Twin Registry: poised for the next generation of twin research.  

PubMed

The University of Washington Twin Registry is a unique community-based registry of twin pairs who join specifically to participate in scientific research. It was founded in 2002 to serve as a resource for investigators throughout the scientific community. Current enrollment exceeds 7,200 pairs, and plans are in place to increase enrollment to 10,000 pairs by 2015. In addition to serving as a recruitment base for new research studies, the registry maintains extensive and continually expanding survey data on physical and mental health, as well as a biorepository that includes DNA from more than 8,800 individual twins. The registry is engaged in linking member data to birth records and to diagnostic and procedure variables for hospital-based care provided to members in Washington State. It also incorporates several innovative variables relevant to the built and social environments, which were created by geocoding twin addresses and linking the resulting coordinates to geospatial information systems databases. This combination of existing data and biospecimens, characterizing a group of twins who are willing to participate in research, is a valuable resource for the new wave of twin studies. These include 'omics', epigenetics, gene-by-environment interactions, and other novel methods to understand human health. PMID:23218177

Strachan, Eric; Hunt, Corinne; Afari, Niloofar; Duncan, Glen; Noonan, Carolyn; Schur, Ellen; Watson, Nathaniel; Goldberg, Jack; Buchwald, Dedra

2013-02-01

468

Tension-dependent removal of pericentromeric shugoshin is an indicator of sister chromosome biorientation.  

PubMed

During mitosis and meiosis, sister chromatid cohesion resists the pulling forces of microtubules, enabling the generation of tension at kinetochores upon chromosome biorientation. How tension is read to signal the bioriented state remains unclear. Shugoshins form a pericentromeric platform that integrates multiple functions to ensure proper chromosome biorientation. Here we show that budding yeast shugoshin Sgo1 dissociates from the pericentromere reversibly in response to tension. The antagonistic activities of the kinetochore-associated Bub1 kinase and the Sgo1-bound phosphatase protein phosphatase 2A (PP2A)-Rts1 underlie a tension-dependent circuitry that enables Sgo1 removal upon sister kinetochore biorientation. Sgo1 dissociation from the pericentromere triggers dissociation of condensin and Aurora B from the centromere, thereby stabilizing the bioriented state. Conversely, forcing sister kinetochores to be under tension during meiosis I leads to premature Sgo1 removal and precocious loss of pericentromeric cohesion. Overall, we show that the pivotal role of shugoshin is to build a platform at the pericentromere that attracts activities that respond to the absence of tension between sister kinetochores. Disassembly of this platform in response to intersister kinetochore tension signals the bioriented state. Therefore, tension sensing by shugoshin is a central mechanism by which the bioriented state is read. PMID:24939933

Nerusheva, Olga O; Galander, Stefan; Fernius, Josefin; Kelly, David; Marston, Adele L

2014-06-15

469

Stickler syndrome type 1 accompanied by membranous vitreous anomaly in two Japanese sisters.  

PubMed

We report two cases of Stickler syndrome type 1 accompanied by a membranous vitreous anomaly in two Japanese sisters. A nine-year-old girl was referred to us for a rhegmatogeneous retinal detachment in her right eye. She had moderate myopia and a membranous vitreous anomaly in both eyes. She also had micrognathia and a saddle nose, leading to a diagnosis of Stickler syndrome type 1. The retinal detachment persisted even after scleral buckling surgery; however, the retina was reattached after 25-gauge microincision vitreous surgery 11 days later. Her seven-year-old sister had been diagnosed with Pierre Robin sequence due to micrognathia, cleft palate, and saddle nose. She was myopic by about -9.0 diopters with a membranous vitreous anomaly in both eyes and circumferential perivascular retinal degeneration in the right eye. Genetic analyses showed that both sisters and their mother carried the same mutation in the COL2A1 gene. The findings in these sisters indicate that retinal detachment is associated with Stickler syndrome type 1. Micro-incison vitreous surgery might be effective for rhegmatogeneous retinal detachment with high vitreous liquefaction. PMID:24164106

Suemori, Shinsuke; Sawada, Akira; Shiraki, Ikumi; Mochizuki, Kiyofumi

2014-01-01

470

Improving Emotion Regulation and Sibling Relationship Quality: The More Fun with Sisters and Brothers Program  

ERIC Educational Resources Information Center

We examined the role of emotion regulation (ER) in improving sibling relationship quality (SRQ) by evaluating the More Fun With Sisters and Brothers Program where 4- to 8-year-old siblings from 95 families were taught emotional and social competencies. Parents reported on SRQ and ER, and sibling interactions were observed in homes. SRQ and ER…

Kennedy, Denise E.; Kramer, Laurie

2008-01-01

471

Empirical Psycho-Aesthetics and Her Sisters: Substantive and Methodological Issues--Part II  

ERIC Educational Resources Information Center

Empirical psycho-aesthetics is approached in this two-part article from two directions. Part I, which appeared in the Winter 2012 issue of "JAE," addressed definitional and organizational issues, including the field's origins, its relation to "sister" disciplines (experimental philosophy, cognitive neuroscience of art, and neuroaesthetics), and…

Konecni, Vladimir J.

2013-01-01

472

EVIDENCE FOR THE CHROMOSOMAL REPLICONS AS UNITS OF SISTER CHROMATID EXCHANGES  

EPA Science Inventory

Current hypotheses of sister chromatid exchange (SCE) formation postulate that sites of SCE induction are associated with active replicons or replicon clusters. We have applied the FCC-SCD technique to in vivo studies of mouse bone marrow cells that have been treated with cycloph...

473

Transitioning from Doctoral Study to the Academy: Theorizing "Trenzas" of Identity for Latina Sister Scholars  

ERIC Educational Resources Information Center

This article focuses on multiple truths pertaining to doctoral education as expressed by three Latina doctoral recipients. These scholars successfully navigated various educational processes with the support of one another, their families, faculty, and their chosen discipline. The authors, as sister scholars, retell their educational journeys…

Espino, Michelle M.; Munoz, Susana M.; Kiyama, Judy Marquez

2010-01-01

474

40 CFR 79.65 - In vivo sister chromatid exchange assay.  

Code of Federal Regulations, 2010 CFR

...of a chemical to enhance the exchange of DNA between two sister chromatids of a duplicating...translocation and ligation of at least two DNA helices. (c) Test method —(1...considered not to induce rearrangements of DNA segments in this system. (iii)...

2010-07-01

475

40 CFR 79.65 - In vivo sister chromatid exchange assay.  

Code of Federal Regulations, 2013 CFR

...of a chemical to enhance the exchange of DNA between two sister chromatids of a duplicating...translocation and ligation of at least two DNA helices. (c) Test method —(1...considered not to induce rearrangements of DNA segments in this system. (iii)...

2013-07-01

476

40 CFR 79.65 - In vivo sister chromatid exchange assay.  

...of a chemical to enhance the exchange of DNA between two sister chromatids of a duplicating...translocation and ligation of at least two DNA helices. (c) Test method —(1...considered not to induce rearrangements of DNA segments in this system. (iii)...

2014-07-01

477

40 CFR 79.65 - In vivo sister chromatid exchange assay.  

Code of Federal Regulations, 2011 CFR

...of a chemical to enhance the exchange of DNA between two sister chromatids of a duplicating...translocation and ligation of at least two DNA helices. (c) Test method —(1...considered not to induce rearrangements of DNA segments in this system. (iii)...

2011-07-01

478

40 CFR 79.65 - In vivo sister chromatid exchange assay.  

Code of Federal Regulations, 2012 CFR

...of a chemical to enhance the exchange of DNA between two sister chromatids of a duplicating...translocation and ligation of at least two DNA helices. (c) Test method —(1...considered not to induce rearrangements of DNA segments in this system. (iii)...

2012-07-01

479

Computerized image analysis of sister chromatid exchanges in Chinese hamster ovary cells  

Microsoft Academic Search

In this paper we show that sister chromatid exchanges (SCE) can be analysed by computer-supported determination of areas and shapes of darkly stained chromatid sections. In combination with appropriate statistical analyses, our method leads to measurements of SCE frequencies in neocarzinostatin-treated Chinese hamster ovary cells which are nearly as precise as the ones obtained by classical microscopical analyses. We discuss

C Schunck; G Obe

1997-01-01

480

Social Functioning among Girls with Fragile X or Turner Syndrome and Their Sisters.  

ERIC Educational Resources Information Center

Social behaviors among girls (ages 6-16) with fragile X (n=8) or Turner syndrome (n=9) were examined to address the role of family environment versus biological determinants of social dysfunction. Compared to their sisters, subjects had lower IQS and higher rating of social and attention problems. (Author/CR)

Mazzocco, Michele M. M.; Baumgardner, Thomas; Freund, Lisa S.; Reiss, Allan L.

1998-01-01

481

20 CFR 725.222 - Conditions of entitlement; parent, brother, or sister.  

...23, 2010. (b)(1) A parent is not entitled to benefits...spouse or child at the time of such miner's death. (2) A brother or sister...survived by a spouse, child, or parent at the time of such miner's death. [65 FR 80054,...

2014-04-01

482

Sister Mary Joseph's nodule as the first presenting sign of primary fallopian tube adenocarcinoma.  

PubMed

Umbilical metastasis (Sister Mary Joseph's nodule) is often the first sign of intraabdominal and/or pelvic carcinoma. We describe the fourth case reported in the literature of Sister Mary Joseph's nodule originating from fallopian tube carcinoma. In a 54-year-old woman, Sister Mary Joseph's nodule was unexpectedly detected during umbilical hernia repair. Subsequent laparoscopy revealed a 2-cm friable tumor located at the fimbriated end of right fallopian tube and 1-cm peritoneal implant in the pouch of Douglas. Laparoscopic bilateral adnexectomy and resection of the peritoneal implant were performed. Because frozen section examination revealed fallopian tube carcinoma, the procedure was continued with laparotomy including total abdominal hysterectomy, omentectomy, and pelvic lymph node sampling. Final diagnosis was stage IIIB fallopian tube carcinoma. The patient received postoperative adjuvant chemotherapy with single-agent carboplatin and has remained alive and with no evidence of disease. It is concluded that in cases of Sister Mary Joseph's nodule, laparoscopy can be a useful tool in the search of the primary tumor in the abdomen and/or pelvis. Laparoscopy can provide crucial information with respect to the location, size, and feasibility of optimal surgical resection of the intraabdominal and/or pelvic tumors. PMID:16698532

Kirshtein, Boris; Meirovitz, Mihai; Okon, Elimelech; Piura, Benjamin

2006-01-01

483

High-functioning autism spectrum disorder and fragile X syndrome: report of two affected sisters  

PubMed Central

Background Fragile X syndrome (FXS) is the most common inherited cause of intellectual disability (ID), as well as the most frequent monogenic cause of autism spectrum disorder (ASD). Men with FXS exhibit ID, often associated with autistics features, whereas women heterozygous for the full mutation are typically less severely affected; about half have a normal or borderline intelligence quotient (IQ). Previous findings have shown a strong association between ID and ASD in both men and women with FXS. We describe here the case of two sisters with ASD and FXS but without ID. One of the sisters presented with high-functioning autism, the other one with pervasive developmental disorder not otherwise specified and low normal IQ. Methods The methylation status of the mutated FMR1 alleles was examined by Southern blot and methylation-sensitive polymerase chain reaction. The X-chromosome inactivation was determined by analyzing the methylation status of the androgen receptor at Xq12. Results Both sisters carried a full mutation in the FMR1 gene, with complete methylation and random X chromosome inactivation. We present the phenotype of the two sisters and other family members. Conclusions These findings suggest that autistic behaviors and cognitive impairment can manifest as independent traits in FXS. Mutations in FMR1, known to cause syndromic autism, may also contribute to the etiology of high-functioning, non-syndromic ASD, particularly in women. Thus, screening for FXS in patients with ASD should not be limited to those with comorbid ID. PMID:22738402

2012-01-01

484

Characteristics of Alcoholism among Catholic Sisters: Results of a National Survey.  

ERIC Educational Resources Information Center

Obtained information on addiction history, intervention and treatment, and family and community patterns from 221 Catholic Sisters in residential treatment for alcoholism. Findings suggest that, although respondents were similar to other women in their vulnerability to addiction, they carried added burdens because of societal expectations of…

Spiegel, Virginia M.

1989-01-01

485

Induction of sister chromatid exchanges by coal dust and tobacco snuff extracts in human peripheral lymphocytes  

Microsoft Academic Search

The organic solvent extracts of sub-bituminous coal dust and tobacco snuff, both together and separately, were tested for the induction of sister chromatid exchanges (SCEs) in human peripheral lymphocytes. The results indicate that these extracts induced SCEs, and that when tested together synergistically induced SCEs in two of three donors. Studies with the organic solvent extracts of all five ranks

James D. Tucker; Tong-Man Ong

1985-01-01

486

They Came with a Purpose: Educational Journeys of Nineteenth-Century Irish Dominican Sister Teachers  

ERIC Educational Resources Information Center

Irish Catholic teaching sisters were major actors in the development of education systems in New World countries such as the United States, Canada, South Africa, Australia and New Zealand. Immigrants themselves, they faced a number of key challenges as they sought to adapt Old World cultural and educational ideas to the education of the immigrant…

Collins, Jenny

2015-01-01

487

Fathers, daughters, and spiritual sisters: Marsha Norman's 'night mother and Tennessee Williams's the Glass Menagerie  

Microsoft Academic Search

Tennessee Williams's Laura Wingfield and Marsha Norman's Jessie Cates are seen here as sisters in disguise. For both characters, their invisible fathers seem somewhat mythic and mystic figures who embody imaginative truth, leading to fulfilling liberation from a world with which each daughter is unequipped to deal. The father's function in both plays is perhaps more a function of his

Louis K. Greiff

1989-01-01

488

Meanings of Sisterhood and Developmental Disability: Narratives from White Nondisabled Sisters  

ERIC Educational Resources Information Center

Integrating thought from critical feminist and disability theorists via a strategic social constructionist perspective, the authors analyzed 10 in-depth qualitative interviews to begin to understand the dialogue between (a) how nondisabled sisters understand themselves and their siblings with developmental disabilities and (b) wider systems of…

McGraw, Lori A.; Walker, Alexis J.

2007-01-01

489

Morphology of Our Galaxy's 'Twin'  

NASA Technical Reports Server (NTRS)

NASA's Spitzer Space Telescope has captured these infrared images of a nearby spiral galaxy that resembles our own Milky Way. The targeted galaxy, known as NGC 7331 and sometimes referred to as our galaxy's twin, is found in the constellation Pegasus at a distance of 50 million light-years. This inclined galaxy was discovered in 1784 by William Herschel, who also discovered infrared light.

The evolution of this galaxy is a story that depends significantly on the amount and distribution of gas and dust, the locations and rates of star formation, and on how the energy from star formation is recycled by the local environment. The new Spitzer images are allowing astronomers to 'read' this story by dissecting the galaxy into its separate components.

The image, measuring 12.6 by 8.2 arcminutes, was obtained by Spitzer's infrared array camera. It is a four-color composite of invisible light, showing emissions from wavelengths of 3.6 microns (blue), 4.5 microns (green), 5.8 microns (yellow) and 8.0 microns (red). These wavelengths are roughly 10 times longer than those seen by the human eye.

The infrared light seen in this image originates from two very different sources. At shorter wavelengths (3.6 to 4.5 microns), the light comes mainly from stars, particularly ones that are older and cooler than our Sun. This starlight fades at longer wavelengths (5.8 to 8.0 microns), where instead we see the glow from clouds of interstellar dust. This dust consists mainly of a variety of carbon-based organic molecules known collectively as polycyclic aromatic hydrocarbons. Wherever these compounds are found, there will also be dust granules and gas, which provide a reservoir of raw materials for future star formation.

One feature that stands out in the Spitzer image is the ring of actively forming stars that surrounds the galaxy center (yellow). This ring, with a radius of nearly 20,000 light-years, is invisible at shorter wavelengths, yet has been detected at sub-millimeter and radio wavelengths. It is made up in large part of polycyclic aromatic hydrocarbons. Spitzer measurements suggest that the ring contains enough gas to produce four billion stars like the Sun.

Three other galaxies are seen below NGC 7331, all about 10 times farther away. From left to right are NGC 7336, NGC 7335 and NGC 7337. The blue dots scattered throughout the images are foreground stars in the Milky Way; the red ones are galaxies that are even more distant.

The Spitzer observations of NGC 7331 are part of a large 500-hour science project, known as the Spitzer Infrared Nearby Galaxy Survey, which will comprehensively study 75 nearby galaxies with infrared imaging and spectroscopy.

2004-01-01

490

DNA hypomethylation, transient neonatal diabetes, and prune belly sequence in one of two identical twins.  

PubMed

One known genetic mechanism for transient neonatal diabetes is loss of methylation at 6q24. The etiology of prune belly sequence is unknown but a genetic defect, affecting the mesoderm from which the triad abdominal muscle hypoplasia, urinary tract abnormalities, and cryptorchidism develop, has been suggested. We investigated a family, including one twin, with transient neonatal diabetes and prune belly sequence. Autoantibody tests excluded type 1 diabetes. Microsatellite marker analysis confirmed the twins being monozygotic. We identified no mutations in ZFP57, KCNJ11, ABCC8, GCK, HNF1A, HNF1B, HNF3B, IPF1, PAX4, or ZIC3. The proband had loss of methylation at the 6q24 locus TNDM and also at the loci IGF2R, DIRAS3, and PEG1, while the other family members, including the healthy monozygotic twin, had normal findings. The loss of methylation on chromosome 6q24 and elsewhere may indicate a generalized maternal hypomethylation syndrome, which accounts for both transient neonatal diabetes and prune belly sequence. PMID:19521719

Laborie, Lene Bjerke; Mackay, Deborah J G; Temple, I Karen; Molven, Anders; Sřvik, Oddmund; Njřlstad, Pĺl Rasmus

2010-02-01

491

Mouse RAD54 Affects DNA Double-Strand Break Repair and Sister Chromatid Exchange  

PubMed Central

Cells can achieve error-free repair of DNA double-strand breaks (DSBs) by homologous recombination through gene conversion with or without crossover. In contrast, an alternative homology-dependent DSB repair pathway, single-strand annealing (SSA), results in deletions. In this study, we analyzed the effect of mRAD54, a gene involved in homologous recombination, on the repair of a site-specific I-SceI-induced DSB located in a repeated DNA sequence in the genome of mouse embryonic stem cells. We used six isogenic cell lines differing solely in the orientation of the repeats. The combination of the three recombination-test substrates used discriminated among SSA, intrachromatid gene conversion, and sister chromatid gene conversion. DSB repair was most efficient for the substrate that allowed recovery of SSA events. Gene conversion with crossover, indistinguishable from long tract gene conversion, preferentially involved the sister chromatid rather than the repeat on the same chromatid. Comparing DSB repair in mRAD54 wild-type and knockout cells revealed direct evidence for a role of mRAD54 in DSB repair. The substrate measuring SSA showed an increased efficiency of DSB repair in the absence of mRAD54. The substrate measuring sister chromatid gene conversion showed a decrease in gene conversion with and without crossover. Consistent with this observation, DNA damage-induced sister chromatid exchange was reduced in mRAD54-deficient cells. Our results suggest that mRAD54 promotes gene conversion with predominant use of the sister chromatid as the repair template at the expense of error-prone SSA. PMID:10757799

Dronkert, Mies L. G.; Beverloo, H. Berna; Johnson, Roger D.; Hoeijmakers, Jan H. J.; Jasin, Maria; Kanaar, Roland

2000-01-01

492

Virginia Farm Healthy Farms and  

E-print Network

Virginia Farm to Table Healthy Farms and Healthy Food for the Common Wealth and Common Good A Strategic Plan for Strengthening Virginia's Food System and Economic Future CV-3 #12;Virginia Farm to Table Edited by E. Bendfeldt C. Tyler-Mackey M. Benson L. Hightower K. Niewolny Healthy Farms and Healthy Food

Liskiewicz, Maciej

493

Lifetime Socioeconomic Position and Twins' Health: An Analysis of 308 Pairs of United States Women Twins  

PubMed Central

Background Important controversies exist about the extent to which people's health status as adults is shaped by their living conditions in early life compared to adulthood. These debates have important policy implications, and one obstacle to resolving them is the relative lack of sufficient high-quality data on childhood and adult socioeconomic position and adult health status. We accordingly compared the health status among monozygotic and dizygotic women twin pairs who lived together through childhood (until at least age 14) and subsequently were discordant or concordant on adult socioeconomic position. This comparison permitted us to ascertain the additional impact of adult experiences on adult health in a population matched on early life experiences. Methods and Findings Our study employed data from a cross-sectional survey and physical examinations of twins in a population-based twin registry, the Kaiser Permanente Women Twins Study Examination II, conducted in 1989 to 1990 in Oakland, California, United States. The study population was composed of 308 women twin pairs (58% monozygotic, 42% dizygotic); data were obtained on childhood and adult socioeconomic position and on blood pressure, cholesterol, post-load glucose, body mass index, waist-to-hip ratio, physical activity, and self-rated health. Health outcomes among adult women twin pairs who lived together through childhood varied by their subsequent adult occupational class. Cardiovascular factors overall differed more among monozygotic twin pairs that were discordant compared to concordant on occupational class. Moreover, among the monozygotic twins discordant on adult occupational class, the working class twin fared worse and, compared to her professional twin, on average had significantly higher systolic blood pressure (mean matched difference = 4.54 mm Hg; 95% confidence interval [CI], 0.10–8.97), diastolic blood pressure (mean matched difference = 3.80 mm Hg; 95% CI, 0.44–7.17), and low-density lipoprotein cholesterol (mean matched difference = 7.82 mg/dl; 95% CI, 1.07–14.57). By contrast, no such differences were evident for analyses based on educational attainment, which does not capture post-education socioeconomic position. Conclusion These results provide novel evidence that lifetime socioeconomic position influences adult health and highlight the utility of studying social plus biological aspects of twinship. PMID:16033303

2005-01-01

494

A healthy outlook.  

PubMed

The sense of coherence-a healthy outlook-can be thought of as a measure of positive health, that is, a factor promoting resilience which enables an individual to remain healthy. Based on National Population Health Survey (NPHS) data, three health measures were analyzed in relation to sense of coherence. The sense of coherence accounted for a substantial proportion of the total variance for two of the three measures. Theoretically, people with a healthy outlook are more able to cope successfully with trauma and stress. According to NPHS data, on average, those who reported at least one traumatic event had a lower sense of coherence than those who did not. For people who experienced trauma during childhood and young adulthood, yet had a strong sense of coherence, the impact of that trauma on their health was diminished. PMID:8679955

Hood, S C; Beaudet, M P; Catlin, G

1996-01-01

495

Healthy People 2010  

NSDL National Science Digital Library

On September 15, Health and Human Services Secretary Donna E. Shalala released "Healthy People 2010 Objectives: Draft for Public Comment," which proposes more than 500 national objectives for improving the health of Americans by the year 2010. First began in 1979, Healthy People, a national initiative to prevent disease and foster better health, is widely used as a strategic management tool by the Federal Government, States, and local communities. This latest incarnation, which succeeds Healthy People 2000, reflects recent advances in science and medicine, as well as emerging public health challenges. The working draft has been placed online specifically to promote public comment and input. Users are encouraged to submit their comments at the site or via surface mail until December 15, 1998. The final report will be issued January 2000.

496

A Healthy Retirement?  

NSDL National Science Digital Library

Nancy has been looking forward to her retirement and a chance to entertain and travel with her husband Jim. But she hasn’t been feeling well. She’s often tired, and recently she’s been experiencing a burning sensation in her lower chest as well as nausea and difficulty breathing. This case was designed for an introductory human biology, anatomy and physiology, or health and wellness course. Its overall purpose is to identify some healthy and not-so-healthy lifestyle choices and the consequences of those choices. It also serves to demonstrate that men and women suffering from the same disease often experience different symptoms.

Henninger, Ann

2003-01-01

497

Simultaneous atelectasis in human bocavirus infected monozygotic twins: was it plastic bronchitis?  

PubMed Central

Background Plastic bronchitis is an extremely rare disease characterized by the formation of tracheobronchial airway casts, which are composed of a fibrinous exudate with rubber-like consistency and cause respiratory distress as a result of severe airflow obstruction. Bronchial casts may be associated with congenital and acquired cardiopathies, bronchopulmonary diseases leading to mucus hypersecretion, and pulmonary lymphatic abnormalities. In recent years, however, there is growing evidence that plastic bronchitis can also be triggered by common respiratory tract infections and thereby cause atelectasis even in otherwise healthy children. Case presentation We report on 22-month-old monozygotic twins presenting with atelectasis triggered by a simple respiratory tract infection. The clinical, laboratory, and radiographic findings given, bronchial cast formation was suspected in both infants but could only be confirmed after bronchoscopy in the first case. Real-time polymerase chain reaction of the removed cast as well as nasal lavage fluid of both infants demonstrated strong positivity for human bocavirus. Conclusion Our case report is the first to describe two simultaneously affected monozygotic twins and substantiates the hypothesis of a contributing genetic factor in the pathophysiology of this disease. In this second report related to human bocavirus, we show additional evidence that this condition can be triggered by a simple respiratory tract infection in previously healthy infants. PMID:24344641

2013-01-01

498

Sister chromatid-based DNA repair is mediated by RAD54, not by DMC1 or TID1.  

PubMed Central

In the mitotic cell cycle of the yeast Saccharomyces cerevisiae, the sister chromatid is preferred over the homologous chromosome (non-sister chromatid) as a substrate for DNA double-strand break repair. However, no genes have yet been shown to be preferentially involved in sister chromatid-mediated repair. We developed a novel method to identify genes that are required for repair by the sister chromatid, using a haploid strain that can embark on meiosis. We show that the recombinational repair gene RAD54 is required primarily for sister chromatid-based repair, whereas TID1, a yeast RAD54 homologue, and the meiotic gene DMC1, are dispensable for this type of repair. Our observations suggest that the sister chromatid repair pathway, which involves RAD54, and the homologous chromosome repair pathway, which involves DMC1, can substitute for one another under some circumstances. Deletion of RAD54 in S.cerevisiae results in a phenotype similar to that found in mammalian cells, namely impaired DNA repair and reduced recombination during mitotic growth, with no apparent effect on meiosis. The principal role of RAD54 in sister chromatid-based repair may also be shared by mammalian and yeast cells. PMID:10228176

Arbel, A; Zenvirth, D; Simchen, G

1999-01-01

499

Establishing a twin registry in Guinea-Bissau.  

PubMed

Twins traditionally retain a special status in many African societies. In Guinea-Bissau, twins are often well regarded yet still suffer from a very high mortality, especially in the perinatal and infant period. At the Bandim Health Project, a health and demographic surveillance site, we have recently established one of the first twin registries in Sub-Saharan Africa. Our short-term aim is to describe twin mortality and morbidity in order to design appropriate health interventions. Our long-term goal is a large-scale database to explore the pathogenesis of prevalent diseases; for example, diabetes mellitus, metabolic syndrome, and infectious diseases such as HIV, tuberculosis, and malaria. A major focus area is also the etiology of low birth weight and how epigenetic processes might modulate the consequences of low birth weight in Sub-Saharan Africa. For this, monozygotic twin studies represent a powerful tool. Though twin studies have been carried out by the Bandim Health Project for more than 30 years, the renewed registry described here was officially established in 2009 and includes both a cohort of newborn twins and a cohort of young and adult twins. Currently more than 1,500 twins are being followed in the two cohorts combined. We believe that the registry holds exciting possibilities and will encourage the establishment of further twin registries across the region. PMID:23088920

Bjerregaard-Andersen, Morten; Gomes, Margarida A; Joaquím, Luis C; Rodrigues, Amabelia; Jensen, Dorte M; Christensen, Kaare; Benn, Christine S; Aaby, Peter; Beck-Nielsen, Henning; Sodemann, Morten

2013-02-01

500

Defining the healthy \\  

Microsoft Academic Search

BACKGROUND: Most studies examining the commensal human oral microbiome are focused on disease or are limited in methodology. In order to diagnose and treat diseases at an early and reversible stage an in-depth definition of health is indispensible. The aim of this study therefore was to define the healthy oral microbiome using recent advances in sequencing technology (454 pyrosequencing). RESULTS:

Egija Zaura; Bart JF Keijser; Susan M Huse; Wim Crielaard

2009-01-01