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1

21 CFR 870.4220 - Cardiopulmonary bypass heart-lung machine console.  

...Cardiopulmonary bypass heart-lung machine console. 870.4220 Section 870...Cardiopulmonary bypass heart-lung machine console. (a) Identification. A cardiopulmonary bypass heart-lung machine console is a device that...

2014-04-01

2

Perfusion of isolated organs and the first heart-lung machine.  

PubMed

In 1885, Max von Frey (1852-1932), while working in Carl Ludwig's Physiological Institute in Leipzig, Germany, designed an apparatus that had criteria characteristic of a heart-lung machine. With this device, he perfused the entire lower extremity of dogs, and took measurements of oxygen consumption, and carbon dioxide and lactate production. In 1935, another type of perfusion apparatus was constructed by Charles A Lindbergh (1902-1973). This device was the result of cooperation with Alexis Carrel (1873-1944) who was a pioneer of experimental organ transplantation. Using Lindbergh's pulsating device, organs such as thyroid, ovary, suprarenal gland, spleen, heart and kidney from fowls and cats were perfused with an oxygenated medium, and were maintained under sterile conditions. Beginning in 1934, John H Gibbon (1903-1973) developed and tested a heart-lung machine to institute cardiopulmonary bypass in cats during experimental occlusion of the pulmonary artery. In 1953, he performed the first successful open-heart operation in a patient using a heart-lung machine. This included elements that were similar to those used by von Frey - ie, the oxygenator and the pumps for continuous circulation of blood. A comparison of the three experimental devices revealed the following: the application for experimental purposes preceded clinical use; the development shifted from Europe to the United States, and was achieved by people who were not specialists; and the intention to build such a device was first purely scientific interest, but later shifted to the care for and treatment of patients with heart and circulatory defects by open-heart surgery. PMID:11586387

Zimmer, H G

2001-09-01

3

Development of a miniaturized heart-lung machine for neonates with congenital heart defect.  

PubMed

Predominantly, standard adult heart lung machines are used for pediatric cardiac surgery, only with individually downsized components. Downsizing is limited, e.g., by the required gas exchange surface. To diminish complications, we developed a new miniaturized heart lung machine (MiniHLM) for neonates, with significantly reduced priming volume and blood contact surface by integration of all major system components in one single device. In particular, a rotary blood pump is centrically integrated into the oxygenator and the cardiotomy reservoir with integrated heat exchanger is directly connected. Thus, tubing is only necessary between patient and MiniHLM. A total priming volume of 102 ml could be achieved for the entire extracorporeal circuit (including arterial/venous line), in contrast to the currently smallest device on the market with 213 ml. In first animal experiments with female New Zealand rabbits, the MiniHLM guaranteed both a sufficient gas exchange and an adequate blood flow; 12 rabbits could successfully be weaned off after 1 hour of aortic clamp time. The first in vitro and in vivo tests confirm the concept of the MiniHLM. Its low priming volume and blood contact surface may significantly reduce complications during heart surgery in neonates. PMID:18812743

Arens, Jutta; Schnöring, Heike; Reisch, Fabian; Vázquez-Jiménez, Jaime F; Schmitz-Rode, Thomas; Steinseifer, Ulrich

2008-01-01

4

Heart-lung transplantation  

PubMed Central

Heart-lung transplantation itself is not a particularly difficult operation technically. It is the setting in which this procedure is performed which is difficult. The three issues of importance in a successful outcome are appropriate harvest of the heart-lung bloc from the donor, careful explant of the heart and lungs of the recipient, and finally the implant of the heart-lung bloc into the recipient. None of this requires extraordinary technical skill, but does require careful coordination and planning as well as adhering to some fundamental principles. One of the major pitfalls encountered is bleeding related to the explant procedure. Another is graft failure related to harvest and/or the implant procedure. The third is injury to either the phrenic nerve(s) or the left recurrent laryngeal nerve related to the explant procedure. Heart-lung transplantation is a major investment in resources of all sorts including financial, personnel, as well as the organs themselves. It is absolutely imperative that this procedure be performed only by experienced surgeons in centers with established expertise. PMID:25132983

Richey, Samuel R.

2014-01-01

5

76 FR 30371 - National Heart, Lung, and Blood Institute; Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Meetings...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-05-25

6

National Heart, Lung, and Blood Institute  

E-print Network

National Heart, Lung, and Blood Institute A T - A - G L A N C E : Physical Activity and Your Heart. The more active you are, the more you will benefit. Types of Physical Activity The four main types of physical activity are aero- bic, muscle-strengthening, bone strengthening, and stretching. · Aerobic

Bandettini, Peter A.

7

National Heart, Lung, and Blood Institute  

E-print Network

your response time. Studies have shown that when you lack sleep, you are more likely to make bad. People who chronically lack sleep are also more likely to become depressed. Health Sleep alsoNational Heart, Lung, and Blood Institute A T - A - G L A N C E : Healthy Sleep S leep is not just

Bandettini, Peter A.

8

Heart-Lung Interactions in Aerospace Medicine  

NASA Technical Reports Server (NTRS)

Few of the heart-lung interactions that are discussed have been studied in any detail in the aerospace environment, but is seems that many such interactions must occur in the setting of altered accelerative loadings and pressure breathing. That few investigations are in progress suggests that clinical and academic laboratory investigators and aerospace organizations are further apart than during the pioneering work on pressure breathing and acceleration tolerance in the 1940s. The purpose is to reintroduce some of the perennial problems of aviation physiology as well as some newer aerospace concerns that may be of interest. Many possible heart-lung interactions are pondered, by necessity often drawing on data from within the aviation field, collected before the modern understanding of these interactions developed, or on recent laboratory data that may not be strictly applicable. In the field of zero-gravity effects, speculation inevitably outruns the sparse available data.

Guy, Harold J. B.; Prisk, Gordon Kim

1991-01-01

9

Heart-lung transplantation for primary pulmonary hypertension  

Microsoft Academic Search

Background. The operation of choice for primary pulmonary hypertension remains controversial, as heart-lung transplantation, single-lung transplantation, and double-lung transplantation have all been advocated.Methods. We reviewed our institution’s experience with heart-lung transplantation for primary pulmonary hypertension.Results. Thirty-nine patients had heart-lung transplantation for primary pulmonary hypertension. Operative mortality rate was 18%, and actuarial survival was 72% at 1 year, 67% at 2

Richard I Whyte; Robert C Robbins; Julie Altinger; Clifford W Barlow; Ramona Doyle; James Theodore; Bruce A Reitz

1999-01-01

10

National Heart, Lung, and Blood Institute  

NSDL National Science Digital Library

The National Heart, Lung, and Blood Institute has crafted this excellent collection of materials for health care professionals. The materials are divided into a dozen sections, including Lung Information, Sleep Information, Interactive Tools and Resources, and Continuing Education Opportunities. The Interactive Tools and Resources area is a gem, as it includes applications for mobile devices such as a menu planner, a Body Mass Index (BMI) calculator, and an asthma mortality map. The Clinical Practice Guidelines area features reports crafted at professional development conferences that deal with cholesterol, obesity, and asthma. Additionally, the Continuing Education Opportunities area features guides to cultural competency and information about upcoming conferences and seminars.

11

78 FR 11657 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting  

Federal Register 2010, 2011, 2012, 2013

...Institutes of Health National Heart, Lung, and Blood Institute...Name of Committee: National Heart, Lung, and Blood Institute...Emphasis Panel; Allogeneic Transplant Recipient Research Resource...Scientific Review/DERA, National Heart, Lung, and Blood...

2013-02-19

12

78 FR 63483 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2013-10-24

13

75 FR 36427 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2010-06-25

14

76 FR 58025 - National Heart, Lung and Blood Institute Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung and Blood Institute Notice of Closed...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-09-19

15

76 FR 12744 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-03-08

16

75 FR 16152 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2010-03-31

17

76 FR 37134 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-06-24

18

76 FR 70154 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-11-10

19

78 FR 69431 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2013-11-19

20

76 FR 12123 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-03-04

21

75 FR 28260 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2010-05-20

22

76 FR 8752 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-02-15

23

78 FR 6122 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2013-01-29

24

77 FR 16843 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2012-03-22

25

76 FR 47218 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-08-04

26

77 FR 2738 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2012-01-19

27

76 FR 3641 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-01-20

28

78 FR 69431 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Office of Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2013-11-19

29

77 FR 33473 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2012-06-06

30

77 FR 76058 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2012-12-26

31

75 FR 61507 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch, DERA, National Heart, Lung, and Blood Institute, 6701...

2010-10-05

32

75 FR 21644 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2010-04-26

33

78 FR 30319 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2013-05-22

34

75 FR 80831 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2010-12-23

35

78 FR 37233 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2013-06-20

36

75 FR 5090 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2010-02-01

37

75 FR 42756 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2010-07-22

38

76 FR 68200 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-11-03

39

78 FR 29375 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2013-05-20

40

78 FR 33428 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...personal privacy. Name of Committee: Heart, Lung, and Blood Initial Review Group...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2013-06-04

41

76 FR 14674 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-03-17

42

77 FR 6571 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2012-02-08

43

77 FR 3479 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2012-01-24

44

75 FR 31796 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2010-06-04

45

75 FR 28032 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2010-05-19

46

75 FR 4092 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2010-01-26

47

76 FR 29772 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-05-23

48

76 FR 16631 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-03-24

49

77 FR 10538 - National Heart, Lung, and Blood Institute Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2012-02-22

50

75 FR 19983 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch, DERA, National Heart, Lung, and Blood Institute,...

2010-04-16

51

78 FR 12766 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National, Heart, Lung, and Blood Institute, 6701...

2013-02-25

52

77 FR 64818 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2012-10-23

53

76 FR 57062 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-09-15

54

78 FR 35637 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2013-06-13

55

76 FR 63625 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-10-13

56

76 FR 11253 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-03-01

57

76 FR 12362 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-03-07

58

77 FR 65568 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2012-10-29

59

77 FR 60705 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2012-10-04

60

78 FR 67370 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...SERVICES National Institutes of Health National Heart, Lung, and Blood Institute; Notice of Closed...invasion of personal privacy. Name of Committee: Heart, Lung, and Blood Initial Review Group; Heart, Lung, and Blood Program Project Review...

2013-11-12

61

77 FR 44640 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of Closed...Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2012-07-30

62

76 FR 37132 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute, Special...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-06-24

63

77 FR 24973 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting  

Federal Register 2010, 2011, 2012, 2013

...National Heart, Lung, and Blood Institute; Notice of Closed...National Heart, Lung, and Blood Institute Special Emphasis Panel; The Kidney in Hypertension. Date: May 17, 2012...National Heart, Lung, and Blood Institute, National...

2012-04-26

64

77 FR 43343 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel; Jackson Heart Study RFA Review. Date: August 15,...

2012-07-24

65

76 FR 25701 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...SERVICES National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...personal privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel, Heart Pumps for Clinical Trials for...

2011-05-05

66

75 FR 70273 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Antihypertensive and Lipid-Lowering to Prevent Heart Attack Trial. Date: December 1,...

2010-11-17

67

77 FR 71429 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel Jackson Heart Study Renewal. Date: December 17,...

2012-11-30

68

78 FR 57866 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...Committee: National Heart, Lung, and Blood...Myeloid Dysplasia Diseases. Date: October...Committee: National Heart, Lung, and Blood...Myeloid Dysplasia Diseases. Date: October...Research; 93.837, Heart and Vascular Diseases Research;...

2013-09-20

69

75 FR 9912 - National Heart, Lung, and Blood Institute; Notice of Meeting  

Federal Register 2010, 2011, 2012, 2013

...of Health National Heart, Lung, and Blood...of the Sickle Cell Disease Advisory Committee...Division of Blood Diseases and Resources, National Heart, Lung, and Blood...Research; 93.837, Heart and Vascular Diseases Research;...

2010-03-04

70

76 FR 57061 - National Heart, Lung, and Blood Institute; Notice of Meeting  

Federal Register 2010, 2011, 2012, 2013

...of Health National Heart, Lung, and Blood...of the Sickle Cell Disease Advisory Committee...Division of Blood Diseases and Resources, National Heart, Lung, and Blood...Research; 93.837, Heart and Vascular Diseases Research;...

2011-09-15

71

75 FR 55807 - National Heart, Lung, and Blood Institute; Notice of Meeting  

Federal Register 2010, 2011, 2012, 2013

...of Health National Heart, Lung, and Blood...of the Sickle Cell Disease Advisory Committee...Division of Blood Diseases and Resources, National Heart, Lung, and Blood...Research; 93.837, Heart and Vascular Diseases Research;...

2010-09-14

72

78 FR 31952 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...Committee: National Heart, Lung, and Blood Institute...Research Projects in Blood Diseases. Date: June 18, 2013...Branch/DERA National Heart, Lung, and Blood Institute...Research; 93.837, Heart and Vascular Diseases Research;...

2013-05-28

73

76 FR 19106 - National Heart, Lung, and Blood Institute; Notice of Meeting  

Federal Register 2010, 2011, 2012, 2013

...of Health National Heart, Lung, and Blood...of the Sickle Cell Disease Advisory Committee...Division of Blood Diseases and Resources, National Heart, Lung, and Blood...Research; 93.837, Heart and Vascular Diseases Research;...

2011-04-06

74

77 FR 13134 - National Heart, Lung, and Blood Institute: Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...Committee: National Heart, Lung, and Blood Institute...Emphasis Panel; Sickle Cell Disease Program Project Grant...Review/DERA, National Heart, Lung, and Blood Institute...Research; 93.837, Heart and Vascular Diseases Research;...

2012-03-05

75

75 FR 8085 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...Branch/DERA, National Heart, Lung, and Blood Institute...Committee: National Heart, Lung, and Blood Institute...InterVEntion before Inotropic Therapy (REVIVE-IT) Date...Branch/DERA, National Heart, Lung, and Blood Institute...Heart and Vascular Diseases Research;...

2010-02-23

76

78 FR 16860 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting  

Federal Register 2010, 2011, 2012, 2013

...Institutes of Health National Heart, Lung, and Blood Institute...Committee: National Heart, Lung, and Blood Institute...Transfusion and Cellular Therapies. Date: April 8, 2013...Review/DERA, National Heart, Lung, and Blood Institute...Heart and Vascular Diseases Research;...

2013-03-19

77

77 FR 14024 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting  

Federal Register 2010, 2011, 2012, 2013

...Institutes of Health National Heart, Lung, and Blood Institute...Name of Committee: National Heart, Lung, and Blood Institute...Emphasis Panel; Development of iPS cell lines. Date: March 26, 2012...Scientific Review/DERA, National Heart, Lung, and Blood...

2012-03-08

78

Heart-lung transplantation: pediatric indications and outcomes.  

PubMed

As indications for heart-lung transplant (HLT) have changed to some degree in the past 30 years, this treatment is being used less frequently in children due to more advanced care of severe heart and lung disease. This is fortunate as the outcomes for HLT are poor compared to other solid organ transplants and this is mainly due to the poorer outcome of the lung graft. PMID:25132980

Spahr, Jonathan E; West, Shawn C

2014-08-01

79

Heart-lung transplantation: pediatric indications and outcomes  

PubMed Central

As indications for heart-lung transplant (HLT) have changed to some degree in the past 30 years, this treatment is being used less frequently in children due to more advanced care of severe heart and lung disease. This is fortunate as the outcomes for HLT are poor compared to other solid organ transplants and this is mainly due to the poorer outcome of the lung graft. PMID:25132980

2014-01-01

80

National Heart, Lung, and Blood Institute -- Information for Researchers  

NSDL National Science Digital Library

Hosted by the National Heart, Lung, and Blood Institute (NHLBI), this website provides a plethora of helpful information and resources for researchers. The site provides abstracts for NHLBI supported research from 1972-present, which also links to the NIH CRISP Database. Online research resources include Programs for Genomic Applications, Available Epidemiology and Clinical Trials Data Sets, as well as links to the NIH Obesity Research Web Site. The site also provides links to other research resources including databases, biologic resources, and training opportunities. In addition, the site links to the NHLBI Population Studies Database, information on the Framingham Heart Study, a section on Workshop and Meeting Summaries, and much more.

81

Regional pulmonary perfusion following human heart-lung transplantation  

SciTech Connect

Ventilation and perfusion scans were obtained in six subjects who had undergone heart-lung transplantation with consequent denervation of the cardiopulmonary axis. Two of the subjects had developed obliterative bronchiolitis, which is believed to be a form of chronic rejection. Their pulmonary function tests demonstrated airflow obstruction and their scintigraphic studies were abnormal. In the remaining four subjects without obstructive airways disease, ventilation and planar perfusion scans were normal. Single photon emission computed tomography imaging of pulmonary perfusion in these patients revealed a layered distribution of blood flow indistinguishable from that of normal individuals. It is concluded that neurogenic mechanisms have little influence on the pattern of local pulmonary blood flow at rest.

Lisbona, R.; Hakim, T.S.; Dean, G.W.; Langleben, D.; Guerraty, A.; Levy, R.D. (Royal Victoria Hospital, Montreal, Quebec (Canada))

1989-08-01

82

National Heart Lung and Blood Institute: Information for Health Professionals  

NSDL National Science Digital Library

Health care professionals and educators will be delighted to learn about this site, provided that they haven't heard about it already. Created by the National Heart Lung and Blood Institute, this site brings together a number of interactive tools and online resources that will be of great use to those in these fields. The site includes such materials as asthma mortality maps of the United States, BMI calculators, and a variety of other health assessment tools, such as menu planners and a ten-year heart attack risk calculator. Additionally, the site contains slide shows and downloadable slide sets on asthma, cholesterol, and high blood pressure that can be used by health care educators.

83

75 FR 50771 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...invasion of personal privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel; NHLBI Nanotechnology Administrative Centers Contract Review. Date: August 20, 2010. Time: 1 p.m. to 2 p.m. Agenda: To review...

2010-08-17

84

78 FR 42967 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting  

Federal Register 2010, 2011, 2012, 2013

...of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel; Pediatric Pulmonary Vascular Disease Bioinformatics Clinical Coordinating Center. Date: August 29, 2013. Time: 9:30 a.m. to 12:00 p.m. Agenda: To review...

2013-07-18

85

77 FR 1703 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...gov. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel Reagents for Human Lung Cell Biology. Date: January 31, 2012. Time: 1 p.m. to 2 p.m. Agenda: To review and evaluate contract proposals....

2012-01-11

86

75 FR 156 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting  

Federal Register 2010, 2011, 2012, 2013

...Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel, Studying Community Programs to Reduce Childhood Obesity. Date: January 29, 2010. Time: 8 a.m. to 2 p.m. Agenda: To review and evaluate contract proposals....

2010-01-04

87

77 FR 54922 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting  

Federal Register 2010, 2011, 2012, 2013

...Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel; Program Project Grant in Hypoxia and Sleep Medicine. Date: September 28, 2012. Time: 8 a.m. to 12 p.m. Agenda: To review and evaluate grant...

2012-09-06

88

77 FR 50517 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting  

Federal Register 2010, 2011, 2012, 2013

...Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel; Maximizing Scientific Return on the Women's Health Initiative Biological Resource. Date: September 7, 2012. Time: 8:30 a.m. to 5:00 p.m. Agenda: To...

2012-08-21

89

76 FR 40923 - National Heart, Lung, and Blood Institute Notice of Closed Meeting  

Federal Register 2010, 2011, 2012, 2013

...Heart, Lung, and Blood Institute Special Emphasis Panel; Reducing Emergency Department Use for Recurrent Exacerbations of Asthma. Date: July 28, 2011. Time: 1 p.m. to 4 p.m. Agenda: To review and evaluate grant applications. Place:...

2011-07-12

90

77 FR 16844 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting  

Federal Register 2010, 2011, 2012, 2013

...Name of Committee: National Heart, Lung, and Blood Institute...Resource-related Application in Congenital Heart Diseases (R24). Date: April 17...Disorders Research; 93.837, Heart and Vascular Diseases Research; 93.838, Lung...

2012-03-22

91

Heart-lung transplantation for cystic fibrosis. 1: Assessment.  

PubMed Central

Forty five patients with cystic fibrosis (age 5-15 years) were assessed for heart-lung transplantation between September 1987 and March 1990. The two main conditions for acceptance were (i) life expectancy less than 2 years and (ii) a severely impaired quality of life. Patients were accepted onto an active waiting list (n = 26), a provisional waiting list (n = 15), or not accepted (n = 4). Selection was made on clinical grounds with objective measurements used as an aid in assessment. As expected, the mean values for objective measures were significantly different between patients on the active waiting list compared with the provisional waiting list/not accepted group for resting heart rate (118/minute v 101/minute), percentage of ideal weight (83.2% v 93.1%), forced expiratory volume at one second as percent of predicted normal (27.3% v 47.6%), Shwachman-Kulczycki score (33.6 v 52.5), Chrispin-Norman x ray score (25.8 v 22.1), 12 minute walk (540 m v 854 m), and minimal oxygen saturation (81.5% v 92%). Psychological evaluation demonstrated a 55% incidence of individual and a 50% incidence of family morbidity. Of the 26 patients accepted onto the active waiting list, 11 have been transplanted (mean waiting time 3.3 months), 10 have died within a mean of 3.7 months of acceptance, and five remain on the active list (mean 5.6 months). PMID:1929505

Whitehead, B; Helms, P; Goodwin, M; Martin, I; Lask, B; Serrano, E; Scott, J P; Smyth, R L; Higenbottam, T W; Wallwork, J

1991-01-01

92

78 FR 7792 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel; SBIR Contract Proposal MRI Myocardinal Biopsy Forceps. Date: February 27, 2013. Time: 4:00 p.m. to 5:30 p.m. Agenda: To review and evaluate contract...

2013-02-04

93

78 FR 7791 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel; Resource related research project on genetically modified rats. Date: February 28, 2013. Time: 9:00 a.m. to 11:00 a.m. Agenda: To review and evaluate...

2013-02-04

94

78 FR 42529 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting  

Federal Register 2010, 2011, 2012, 2013

...Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel Resource related project on genetically modified mice. Date: August 14, 2013. Time: 11:00 a.m. to 1:30 p.m. Agenda: To review and evaluate...

2013-07-16

95

77 FR 16246 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting  

Federal Register 2010, 2011, 2012, 2013

...unwarranted invasion of personal privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel; Omics and Genetic Analysis. Date: April 6, 2012. Time: 8:30 a.m. to 12 p.m. Agenda: To review and evaluate...

2012-03-20

96

78 FR 19725 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting  

Federal Register 2010, 2011, 2012, 2013

...personal privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel; Training in Lung Omics. Date: April 26, 2013. Time: 8:00 a.m. to 5:00 p.m. Agenda: To review and evaluate grant applications....

2013-04-02

97

The cough response to ultrasonically nebulized distilled water in heart-lung transplantation patients  

SciTech Connect

As a result of clinical heart-lung transplantation, the lungs are denervated below the level of the tracheal anastomosis. It has been questioned whether afferent vagal reinnervation occurs after surgery. Here we report the cough frequency, during inhalation of ultrasonically nebulized distilled water, of 15 heart-lung transplant patients studied 6 wk to 36 months after surgery. They were compared with 15 normal subjects of a similar age and sex. The distribution of the aerosol was studied in five normal subjects using /sup 99m/technetium diethylene triamine pentaacetate (/sup 99m/Tc-DTPA) in saline. In seven patients, the sensitivity of the laryngeal mucosa to instilled distilled water (0.2 ml) was tested at the time of fiberoptic bronchoscopy by recording the cough response. Ten percent of the aerosol was deposited onto the larynx and trachea, 56% on the central airways, and 34% in the periphery of the lung. The cough response to the aerosol was strikingly diminished in the patients compared with normal subjects (p less than 0.001), but all seven patients coughed when distilled water was instilled onto the larynx. As expected, the laryngeal mucosa of heart-lung transplant patients remains sensitive to distilled water. However, the diminished coughing when the distilled water is distributed by aerosol to the central airways supports the view that vagal afferent nerves do not reinnervate the lungs after heart-lung transplantation, up to 36 months after surgery.

Higenbottam, T.; Jackson, M.; Woolman, P.; Lowry, R.; Wallwork, J.

1989-07-01

98

78 FR 27411 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...National Heart, Lung, and Blood Institute Special Emphasis Panel; NHLBI Resource-Related Project for Stem Cells and Cardiomyopathy. Date: June 6, 2013. Time: 1:00 p.m. to 3:00 p.m. Agenda: To review and evaluate grant applications....

2013-05-10

99

77 FR 59935 - National Heart, Lung, And Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013

...Heart, Lung, and Blood Institute Special Emphasis Panel; NHLBI Resource-Related Research Project for Stem Cells and Cardiomyopathy. Date: October 22, 2012. Time: 1:00 p.m. to 3:00 p.m. Agenda: To review and evaluate grant...

2012-10-01

100

Computational models for the study of heart-lung interactions in mammals  

PubMed Central

[The operation and regulation of the lungs and the heart are closely related. This is evident when examining the anatomy within the thorax cavity, in the brainstem and in the aortic and carotid arteries where chemoreceptors and baroreceptors, which provide feedback affecting the regulation of both organs, are concentrated. This is also evident in phenomena such as respiratory sinus arrhythmia where the heart rate increases during inspiration and decreases during expiration, in other types of synchronization between the heart and the lungs known as cardioventilatory coupling and in the association between heart failure and sleep apnea where breathing is interrupted periodically by periods of no-breathing. The full implication and physiological significance of the cardio-respiratory coupling under normal, pathological or extreme physiological conditions are still unknown and are subject to ongoing investigation both experimentally and theoretically using mathematical models. This paper reviews mathematical models that take heart-lung interactions into account. The main ideas behind low dimensional, phenomenological models for the study of the heart-lung synchronization and sleep apnea are described first. Higher dimensions, physiology-based models are described next. These models can vary widely in detail and scope and are characterized by the way the heart-lung interaction is taken into account: via gas exchange, via the central nervous system, via the mechanical interactions and via time delays. The paper emphasizes the need for the integration of the different sources of heart-lung coupling as well as the different mathematical approaches.] PMID:22140008

Ben-Tal, Alona

2011-01-01

101

[8.5 year-follow-up of combined heart-lung transplantation in a patient].  

PubMed

To summarize the case of combined heart-lung transplantation for a patient who survived for 8.5 years. On September 20, 2003, at Second Xiangya Hospital of Central South University, homologous heartlung transplantation was performed on a male patient who was diagnosed with cardiopulmonary failure secondary to congenital ventricular septal defect with severe pulmonary hypertension. Heart-lung allograft was preserved with 1500 mL modified St.Thomas solution and 3000 mL modified LPD solution. Postoperative immunosuppressive therapies included: methylprednisolone and human anti-lymphocyte globulin protein in the induction period; and combination of ciclosporin A, CellCept and prednisolone in the stable period. In 2007, the treatment was changed to CellCept mg, twice a day+FK506 4 mg, twice a day. The patient lived 8.5 years of normal life with cardiac function of NYHA I-II. Echocardiogram showed left ventricular ejection fraction of 61% to 74%. Heart-lung transplantation proved reliable therapy modality for terminal cardiopulmonary failure. Excellent donor organ preservation and proper perioperative treatment are key factors for long-term survival after heart-lung transplantation. PMID:23456080

Shang, Baopeng; Hu, Jianguo; Zhou, Xinmin; Zhang, Wei; Liao, Xiaobo; Li, Jianming

2013-02-01

102

77 FR 24728 - National Heart, Lung, and Blood Institute Notice of Closed Meeting  

Federal Register 2010, 2011, 2012, 2013

...of personal privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel; Sudden Cardiac Death in the Young. Date: May 16, 2012. Time: 11 a.m. to 2 p.m. Agenda: To review and evaluate contract...

2012-04-25

103

A novel approach in extracorporeal circulation: individual, integrated, and interactive heart-lung assist (I3-Assist).  

PubMed

Extracorporeal life support (ECLS) is a well-established technique for the treatment of different cardiac and pulmonary diseases, e.g., congenital heart disease and acute respiratory distress syndrome. Additionally, severely ill patients who cannot be weaned from the heart-lung machine directly after surgery have to be put on ECLS for further therapy. Although both systems include identical components, a seamless transition is not possible yet. The adaption of the circuit to the patients' size and demand is limited owing to the components available. The project I³-Assist aims at a novel concept for extracorporeal circulation. To better match the patient's therapeutic demand of support, an individual number of one-size oxygenators and heat exchangers will be combined. A seamless transition between cardiopulmonary bypass and ECLS will be possible as well as the exchange of components during therapy to enhance circuit maintenance throughout long-term support. Until today, a novel oxygenator and heat exchanger along with a simplified manufacturing protocol have been established. The first layouts of the unit to allow the spill- and bubble-free connection and disconnection of modules as well as improved cannulas and a rotational pump are investigated using computational fluid dynamics. Tests were performed according to current guidelines in vitro and in vivo. The test results show the feasibility and potential of the concept. PMID:24327525

Wagner, Georg; Schlanstein, Peter; Fiehe, Sandra; Kaufmann, Tim; Kopp, Rüdger; Bensberg, Ralf; Schmitz-Rode, Thomas; Steinseifer, Ulrich; Arens, Jutta

2014-04-01

104

Prostacyclin (epoprostenol) and heart-lung transplantation as treatments for severe pulmonary hypertension  

Microsoft Academic Search

OBJECTIVE--To determine whether epoprostenol (prostacyclin, PGI2) or heart-lung transplantation (HLT), or both improves survival of patients with severe pulmonary hypertension. DESIGN--This was a prospective study where the effects of epoprostenol were compared with conventional treatment. Also, the benefits of epoprostenol and HLT were assessed by comparing survival in this group with that of 120 patients at the Mayo Clinic before

T W Higenbottam; D Spiegelhalter; J P Scott; V Fuster; A T Dinh-Xuan; N Caine; J Wallwork

1993-01-01

105

Influence of Red Blood Cells on Lung Function in an ex Vivo Rat Heart-Lung Model  

Microsoft Academic Search

Crystalloid perfusates commonly are utilized for lung preservation in extracorporeal small animal lung models. However, the function of these grafts is limited. In a new ex-vivo rat heart-lung model the role of red blood cells added to the crystalloid perfusate was investigated. Heart-lung blocks were rapidly excised (n = 9, each group) and the blocks were connected to the extracorporeal

Tatsuo Fukuse; Johannes M. Albes; Yutaka Takahashi; Harald Brandes; Bernard Hausen; Hans-Joachim Schäfers

1995-01-01

106

Elucidating Nature's Solutions to Heart, Lung, and Blood Diseases and Sleep Disorders  

PubMed Central

Evolution has provided a number of animal species with extraordinary phenotypes. Several of these phenotypes allow species to survive and thrive in environmental conditions that mimic disease states in humans. The study of evolved mechanisms that responsible for these phenotypes may provide insights into the basis of human disease and guide the design of new therapeutic approaches. Examples include species that tolerate acute or chronic hypoxemia like deep-diving mammals and high-altitude inhabitants, as well as those that hibernate and interrupt their development when exposed to adverse environments. The evolved traits exhibited by these animal species involve modifications of common biological pathways that affect metabolic regulation, organ function, antioxidant defenses, and oxygen transport. In 2006, the National Heart, Lung, and Blood Institute (NHLBI) released a funding opportunity announcement to support studies that were designed to elucidate the natural molecular and cellular mechanisms of adaptation in species that tolerate extreme environmental conditions. The rationale for this funding opportunity is detailed in this Special Article, and the specific evolved mechanisms examined in the supported research are described. Also highlighted are past medical advances achieved through the study of animal species that have evolved extraordinary phenotypes as well as the expectations for new understanding of nature’s solutions to heart, lung, blood, and sleep disorders through future research in this area. PMID:22461362

Carey, Hannah V.; Martin, Sandra L.; Horwitz, Barbara A.; Yan, Lin; Bailey, Shannon M.; Podrabsky, Jason; Storz, Jay F.; Ortiz, Rudy M.; Wong, Renee P.; Lathrop, David A.

2012-01-01

107

Hypertension as a marker for later development of end-stage renal failure after lung and heart-lung transplantation: A cohort study  

Microsoft Academic Search

BackgroundTime to renal failure after transplantation is not well known and the prognosis of lung and heart-lung transplantation with respect to end-stage renal failure and related factors has not been investigated in detail. We determined the predictors of end-stage renal failure after lung or heart-lung transplant using multivariate analysis.

H. Kunst; D. Thompson; M. Hodson

2004-01-01

108

Heart–lung and lung transplantation in grown-up congenital heart disease: long-term single centre experience  

Microsoft Academic Search

Objective: Because of considerable progress in paediatric cardiac surgery life expectancy of patients with congenital heart disease (CHD) has improved significantly over the years. There are a growing number of adults with CHD presenting with progressive decline of cardiopulmonary function and Eisenmenger's syndrome. We analysed our experience with heart–lung and lung transplantation in this patient group. Methods: Since 1988, a

Heidi Goerler; Andre Simon; Bernhard Gohrbandt; Christian Hagl; Petra Oppelt; Juergen Weidemann; Axel Haverich; Martin Strueber

2007-01-01

109

Intraoperative management of heart-lung interactions: "from hypothetical prediction to improved titration".  

PubMed

Extensive literature describes the suitability of dynamic parameters to predict responsiveness in fluid. However, based on heart-lung interactions, these parameters can have serious limitations, including the use of protective lung ventilation. Although the latter seems to be beneficial for healthy patients undergoing high-risk surgery, the intraoperative interpretation of dynamic parameters to predict fluid responsiveness can be hazardous. In this context, the attending physician could, alternatively, titrate the need of fluids with a small fluid challenge, which remains unaffected by low tidal volume, the presence of arrhythmia, or the presence of spontaneous ventilation. When intraoperative prediction of fluid responsiveness is required in mechanically ventilated patients, "improved" titration should be preferred to a hypothetical prediction. PMID:25127853

Ouattara, A; Dewitte, A; Rozé, H

2014-01-01

110

Conformal piezoelectric energy harvesting and storage from motions of the heart, lung, and diaphragm  

PubMed Central

Here, we report advanced materials and devices that enable high-efficiency mechanical-to-electrical energy conversion from the natural contractile and relaxation motions of the heart, lung, and diaphragm, demonstrated in several different animal models, each of which has organs with sizes that approach human scales. A cointegrated collection of such energy-harvesting elements with rectifiers and microbatteries provides an entire flexible system, capable of viable integration with the beating heart via medical sutures and operation with efficiencies of ?2%. Additional experiments, computational models, and results in multilayer configurations capture the key behaviors, illuminate essential design aspects, and offer sufficient power outputs for operation of pacemakers, with or without battery assist. PMID:24449853

Dagdeviren, Canan; Yang, Byung Duk; Su, Yewang; Tran, Phat L.; Joe, Pauline; Anderson, Eric; Xia, Jing; Doraiswamy, Vijay; Dehdashti, Behrooz; Feng, Xue; Lu, Bingwei; Poston, Robert; Khalpey, Zain; Ghaffari, Roozbeh; Huang, Yonggang; Slepian, Marvin J.; Rogers, John A.

2014-01-01

111

Conformal piezoelectric energy harvesting and storage from motions of the heart, lung, and diaphragm.  

PubMed

Here, we report advanced materials and devices that enable high-efficiency mechanical-to-electrical energy conversion from the natural contractile and relaxation motions of the heart, lung, and diaphragm, demonstrated in several different animal models, each of which has organs with sizes that approach human scales. A cointegrated collection of such energy-harvesting elements with rectifiers and microbatteries provides an entire flexible system, capable of viable integration with the beating heart via medical sutures and operation with efficiencies of ?2%. Additional experiments, computational models, and results in multilayer configurations capture the key behaviors, illuminate essential design aspects, and offer sufficient power outputs for operation of pacemakers, with or without battery assist. PMID:24449853

Dagdeviren, Canan; Yang, Byung Duk; Su, Yewang; Tran, Phat L; Joe, Pauline; Anderson, Eric; Xia, Jing; Doraiswamy, Vijay; Dehdashti, Behrooz; Feng, Xue; Lu, Bingwei; Poston, Robert; Khalpey, Zain; Ghaffari, Roozbeh; Huang, Yonggang; Slepian, Marvin J; Rogers, John A

2014-02-01

112

Necrotic, ulcerative bronchitis, the presenting feature of lymphoproliferative disease following heart-lung transplantation.  

PubMed Central

Following heart-lung transplantation two of 21 patients who survived more than 100 days developed post-transplant lymphoproliferative disease. Both presented with localised ulcerative bronchitis documented at flexible bronchoscopy four months after transplantation. Histological examination showed necrosis with acute inflammation and ulceration. Case 2 demonstrated lymphoproliferative disease from biopsies subsequently taken at rigid bronchoscopy. Case 1 later developed lung nodules and a monoclonal high grade B cell non-Hodgkin's lymphoma was confirmed by an open lung biopsy. The bronchoscopic features described should alert clinicians to post-transplant lymphoproliferative disease as an underlying diagnosis and suggest that bronchus associated lymphoid tissue is the initial site for clonal proliferation in the disease. Images PMID:7701465

Egan, J. J.; Hasleton, P. S.; Yonan, N.; Rahman, A. N.; Deiraniya, A. K.; Carroll, K. B.; Woodcock, A. A.

1995-01-01

113

Cardiovascular Tissue Engineering Research Support at the National Heart, Lung, and Blood Institute  

PubMed Central

Tissue engineering aims at building three-dimensional living substitutes that are equal to or better than the damaged tissue to be replaced. The development of such a tissue replacement requires a multidisciplinary approach and careful attention to the optimal cell source, the interactions of growth factors and extracellular milieu, and the scaffolding design. This article is a review of the National Heart, Lung, and Blood Institute's (NHLBI) tissue engineering programs, which support research efforts to translate novel approaches for the treatment of cardiovascular disease. Recent progress is discussed, which highlights some major questions relevant to cardiovascular tissue engineering. NHLBI has a strong interest in tissue engineering and will continue to foster the practical, clinical, and commercial development of research discoveries in this emerging field. PMID:23580772

Lundberg, Martha Shauck

2013-01-01

114

Text Categorization of Heart, Lung, and Blood Studies in the Database of Genotypes and Phenotypes (dbGaP) Utilizing n-grams and Metadata Features  

PubMed Central

The database of Genotypes and Phenotypes (dbGaP) allows researchers to understand phenotypic contribution to genetic conditions, generate new hypotheses, confirm previous study results, and identify control populations. However, effective use of the database is hindered by suboptimal study retrieval. Our objective is to evaluate text classification techniques to improve study retrieval in the context of the dbGaP database. We utilized standard machine learning algorithms (naive Bayes, support vector machines, and the C4.5 decision tree) trained on dbGaP study text and incorporated n-gram features and study metadata to identify heart, lung, and blood studies. We used the ?2 feature selection algorithm to identify features that contributed most to classification performance and experimented with dbGaP associated PubMed papers as a proxy for topicality. Classifier performance was favorable in comparison to keyword-based search results. It was determined that text categorization is a useful complement to document retrieval techniques in the dbGaP. PMID:23926434

Ross, Mindy K.; Lin, Ko-Wei; Truong, Karen; Kumar, Abhishek; Conway, Mike

2013-01-01

115

Text Categorization of Heart, Lung, and Blood Studies in the Database of Genotypes and Phenotypes (dbGaP) Utilizing n-grams and Metadata Features.  

PubMed

The database of Genotypes and Phenotypes (dbGaP) allows researchers to understand phenotypic contribution to genetic conditions, generate new hypotheses, confirm previous study results, and identify control populations. However, effective use of the database is hindered by suboptimal study retrieval. Our objective is to evaluate text classification techniques to improve study retrieval in the context of the dbGaP database. We utilized standard machine learning algorithms (naive Bayes, support vector machines, and the C4.5 decision tree) trained on dbGaP study text and incorporated n-gram features and study metadata to identify heart, lung, and blood studies. We used the ?(2) feature selection algorithm to identify features that contributed most to classification performance and experimented with dbGaP associated PubMed papers as a proxy for topicality. Classifier performance was favorable in comparison to keyword-based search results. It was determined that text categorization is a useful complement to document retrieval techniques in the dbGaP. PMID:23926434

Ross, Mindy K; Lin, Ko-Wei; Truong, Karen; Kumar, Abhishek; Conway, Mike

2013-01-01

116

Gastrointestinal complications in heart and in heart-lung transplant patients.  

PubMed

Gastrointestinal complications after heart and heart-lung transplantation are being recognized and reported more frequently in the literature as a cause of significant morbidity. Between July 1983 and December 1989, 131 consecutive patients underwent 133 heart or heart-lung transplant procedures at The Johns Hopkins Hospital. Immunosuppression consisted of either cyclosporine and prednisone or cyclosporine, prednisone, and azathioprine. Twenty-eight patients (21%) had 38 gastrointestinal complications, including visceral perforations (n = 6), gastrocutaneous fistula (n = 1), retroperitoneal abscess (n = 1), cholecystitis (n = 5), gastric atony (n = 1), perianal abscess (n = 1), gastrointestinal bleeding (n = 4), esophagitis (n = 2), pancreatitis (n = 2), pancreatic abscess (n = 2), hepatitis (n = 2), cytomegalovirus infection (n = 3), and diarrhea (n = 8). Among this group of 28 patients, 17 operative procedures were needed by 13 patients (46%), for an incidence of major abdominal procedures in the entire transplant cohort of 10% (13/131). Operations included cholecystectomy (n = 5), colon resection with colostomy (n = 3), closure of perforated gastroduodenal ulcer (n = 3) and repair of gastrocutaneous fistula (n = 1), drainage of pancreatic abscess (n = 2), pyloroplasty (n = 1) and incision and drainage of perianal abscess (n = 1). The operative mortality rate was 8% (1/13). Overall survival in patients with gastrointestinal complications was no different than that in the entire transplant population. Age, gender, race, and number of rejection episodes did not correlate with the presence of gastrointestinal complications. Patients with gastrointestinal pathologic conditions necessitating surgery often had atypical presentations, with subtle clinical findings but with common general surgical problems.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:1911797

Augustine, S M; Yeo, C J; Buchman, T G; Achuff, S C; Baumgartner, W A

1991-01-01

117

Severe asthma: lessons learned from the National Heart, Lung, and Blood Institute Severe Asthma Research Program.  

PubMed

The National Heart, Lung, and Blood Institute Severe Asthma Research Program (SARP) has characterized over the past 10 years 1,644 patients with asthma, including 583 individuals with severe asthma. SARP collaboration has led to a rapid recruitment of subjects and efficient sharing of samples among participating sites to conduct independent mechanistic investigations of severe asthma. Enrolled SARP subjects underwent detailed clinical, physiologic, genomic, and radiological evaluations. In addition, SARP investigators developed safe procedures for bronchoscopy in participants with asthma, including those with severe disease. SARP studies revealed that severe asthma is a heterogeneous disease with varying molecular, biochemical, and cellular inflammatory features and unique structure-function abnormalities. Priorities for future studies include recruitment of a larger number of subjects with severe asthma, including children, to allow further characterization of anatomic, physiologic, biochemical, and genetic factors related to severe disease in a longitudinal assessment to identify factors that modulate the natural history of severe asthma and provide mechanistic rationale for management strategies. PMID:22095547

Jarjour, Nizar N; Erzurum, Serpil C; Bleecker, Eugene R; Calhoun, William J; Castro, Mario; Comhair, Suzy A A; Chung, Kian Fan; Curran-Everett, Douglas; Dweik, Raed A; Fain, Sean B; Fitzpatrick, Anne M; Gaston, Benjamin M; Israel, Elliot; Hastie, Annette; Hoffman, Eric A; Holguin, Fernando; Levy, Bruce D; Meyers, Deborah A; Moore, Wendy C; Peters, Stephen P; Sorkness, Ronald L; Teague, W Gerald; Wenzel, Sally E; Busse, William W

2012-02-15

118

Melatonin protects the heart, lungs and kidneys from oxidative stress under intermittent hypobaric hypoxia in rats.  

PubMed

Melatonin (N-acetyl-5-methoxytryptamine) is the main secretory product of the pineal gland in all mammals including humans, but it is also produced in other organs. It has been previously demonstrated to be a powerful organ-protective substance under oxidative stress conditions. The aim of this study was to evaluate the protective effect of melatonin in several organs such as heart, lung, kidney, and of the reproductive system, such as testis and epididymis in animals exposed to intermittent hypobaric hypoxia and therefore exposed to oxidative stress and analyzed by lipid peroxidation. Ten-week-old male Wistar rats were divided into 6 groups for 96 hours during 32 days under: 1) Normobaric conditions, 2) plus physiologic solution, 3) plus melatonin, 4) intermittent hypobaric hypoxia, 5 plus physiologic solution and 6) plus melatonin. The animals were injected with melatonin (10 mg/kg body weight) at an interval of 96 hours during 32 days. Results indicated that melatonin decreased lipid peroxidation in heart, kidneys and lung under intermittent hypobaric hypoxia conditions. However, it did not exhibit any protective effect in liver, testis, epididymis and sperm count. PMID:22688988

Farías, Jorge G; Zepeda, Andrea B; Calaf, Gloria M

2012-01-01

119

[Techniques involved in the protection of the lung and heart-lung for the purpose of transplantation].  

PubMed

Impaired healing of the bronchial anastomosis and its subsequent complications has been an important problem following lung transplantation. The decrease in the dosage of steroids, the use of cyclosporine immunosuppressive therapy and the use of an omental flap to revascularize rapidly the bronchial anastomosis, have reduced considerably the incidence of these post-operative bronchial complications. We have recently demonstrated that the application of a pedicled intercostal muscle graft or peritracheal membrane adipose tissue wrap on the bronchial anastomosis improved bronchial healing by restoring a vascular flow across the anastomosis within 7 days after left lung allotransplantation. Since the introduction of heart-lung transplantation at Stanford (USA) in 1981 and Pittsburgh in 1982 for the treatment of Eisenmenger's syndrome and terminal pulmonary vascular diseases, more than 250 combined heart-lung transplantations have been carried out throughout the world. However the present intermediate and long term results obtained with this operation have not yet reached the same level of success as cardiac transplantation alone. While several factors such as selection of candidates and donors have played a role in this difference, a prominent cause has been the lack of a reliable and simple method for pulmonary protection against prolonged ischemia. Most of the techniques proposed against ischemia can be classified as normothermic or static hypothermic cardiopulmonary preservation. The utilization of the normothermic method has not always been successful. For this reason, interest has now been directed towards the potential for hypothermic preservation of the heart-lung bloc and the use of free radical scavenger therapy in the reduction of reperfusion injury. PMID:2270341

Le Gal, Y M

1990-01-01

120

Optogenetic sensors and effectors: CHROMus—the Cornell Heart Lung Blood Institute Resource for Optogenetic Mouse Signaling  

PubMed Central

Significant progress has been made in the last decade in the development of optogenetic effectors and sensors that can be deployed to understand complex biological signaling in mammals at a molecular level, without disrupting the distributed, lineage specific signaling circuits that comprise nuanced physiological responses. A major barrier to the widespread exploitation of these imaging tools, however, is the lack of readily available genetic reagents that can be easily combined to probe complex biological processes. Ideally, one could envision purpose–produced mouse lines expressing optically compatible sensors and effectors, sensor pairs in distinct lineages, or sensor pairs in discrete subcellular compartments, such that they could be crossed to enable in vivo imaging studies of unprecedented scientific power. Such lines could also be combined with mice to determine the alteration in signaling accompanying targeted gene deletion or addition. In order to address this lack, the National Heart Lung and Blood Institute has recently funded an optogenetic resource designed to create optically compatible, combinatorial mouse lines that will advance NHLBI research. Here we review recent advances in optogenetic sensor and effectors and describe the rationale and goals for the establishment of the Cornell/National Heart Lung Blood Resource for Optogenetic Mouse Signaling (CHROMus).

Shui, Bo; Lee, Jane C.; Reining, Shaun; Lee, Frank K.; Kotlikoff, Michael I.

2014-01-01

121

Changes in the practice of percutaneous coronary intervention: a comparison of enrollment waves in the national heart, lung, and blood institute (NHLBI) dynamic registry  

Microsoft Academic Search

The National Heart, Lung, and Blood Institute Dynamic Registry includes 15 clinical sites in wave 1, and 16 sites in wave 2 as well as a data-coordinating center. The first wave of enrollment began in July 1997 and was completed in February 1998. The second wave began in February 1999 and ended in June 1999. There were a total of

Warren K Laskey; David O Williams; Helen Aslanidou Vlachos; Howard Cohen; David R Holmes; Spencer B King; Sheryl F Kelsey; James Slater; David Faxon; Mahdi Al-Bassam; Elizabeth Block; Katherine M Detre

2001-01-01

122

Capacitive on-line hematocrit sensor design based on impedance spectroscopy for use in hemodialysis machines  

Microsoft Academic Search

This paper presents a new design for an on-line and in-line hematocrit (HCT) sensor. Special feature of the sensor is the capability to measure the hematocrit of a blood sample inside standard plastic tubing widely used in medical equipment. No blood sample has to be extracted out of existing extracorporeal blood circulation systems such as hemodialysis machines or heart-lung machines.

Dennis Trebbels; David Hradetzky; Roland Zengerle

2009-01-01

123

Complication Probability Models for Radiation-Induced Heart Valvular Dysfunction: Do Heart-Lung Interactions Play a Role?  

PubMed Central

Purpose The purpose of this study is to compare different normal tissue complication probability (NTCP) models for predicting heart valve dysfunction (RVD) following thoracic irradiation. Methods All patients from our institutional Hodgkin lymphoma survivors database with analyzable datasets were included (n?=?90). All patients were treated with three-dimensional conformal radiotherapy with a median total dose of 32 Gy. The cardiac toxicity profile was available for each patient. Heart and lung dose-volume histograms (DVHs) were extracted and both organs were considered for Lyman-Kutcher-Burman (LKB) and Relative Seriality (RS) NTCP model fitting using maximum likelihood estimation. Bootstrap refitting was used to test the robustness of the model fit. Model performance was estimated using the area under the receiver operating characteristic curve (AUC). Results Using only heart-DVHs, parameter estimates were, for the LKB model: D50?=?32.8 Gy, n?=?0.16 and m?=?0.67; and for the RS model: D50?=?32.4 Gy, s?=?0.99 and ??=?0.42. AUC values were 0.67 for LKB and 0.66 for RS, respectively. Similar performance was obtained for models using only lung-DVHs (LKB: D50?=?33.2 Gy, n?=?0.01, m?=?0.19, AUC?=?0.68; RS: D50?=?24.4 Gy, s?=?0.99, ??=?2.12, AUC?=?0.66). Bootstrap result showed that the parameter fits for lung-LKB were extremely robust. A combined heart-lung LKB model was also tested and showed a minor improvement (AUC?=?0.70). However, the best performance was obtained using the previously determined multivariate regression model including maximum heart dose with increasing risk for larger heart and smaller lung volumes (AUC?=?0.82). Conclusions The risk of radiation induced valvular disease cannot be modeled using NTCP models only based on heart dose-volume distribution. A predictive model with an improved performance can be obtained but requires the inclusion of heart and lung volume terms, indicating that heart-lung interactions are apparently important for this endpoint. PMID:25360627

Cella, Laura; Palma, Giuseppe; Deasy, Joseph O.; Oh, Jung Hun; Liuzzi, Raffaele; D'Avino, Vittoria; Conson, Manuel; Pugliese, Novella; Picardi, Marco; Salvatore, Marco; Pacelli, Roberto

2014-01-01

124

Ethnic differences in the presentation, treatment strategy, and outcomes of percutaneous coronary intervention (a report from the National Heart, Lung, and Blood Institute Dynamic Registry)  

Microsoft Academic Search

Information about the impact of race\\/ethnicity on adverse outcomes after percutaneous coronary intervention (PCI) in the modern era is limited. Using consecutive patients from the National Heart, Lung, and Blood Institute Dynamic Registry, this study investigated differences in clinical presentation, treatment strategy, and acute and long-term outcomes in 3,669 white, 446 black, 301 Hispanic, and 201 Asian patients who underwent

James Slater; Faith Selzer; Sharmila Dorbala; Deborah Tormey; Helen A Vlachos; Robert L Wilensky; Alice K Jacobs; Warren K Laskey; John S Douglas; David O Williams; Sheryl F Kelsey

2003-01-01

125

Funding mechanisms and program management at the National Heart, Lung, and Blood Institute: confronting new challenges and exploring new opportunities.  

PubMed

Over the past 8 years, the National Institutes of Health (NIH) budget appropriation has lost purchasing power, with erosion of the benefits of the doubling of the budget less than a decade ago. For the first time in 40 years, the NIH appropriation in fiscal year 2011 was 1% less than in the previous year. The National Heart, Lung, and Blood Institute (NHLBI) has been closely managing its funds to protect its core functions: support and conduct of research, and training of biomedical research scientists. Rigorous evaluations of funding mechanisms, management of clinical studies, set-aside programs and funding guidelines are designed to help the Institute, in consultation with its advisory council, to minimize the long-term impact of extreme resource limitations on the advance and conduct of science. This report describes some recent actions taken by the NHLBI to maximize support for investigator-initiated research, maintain a balanced portfolio, and provide as much support as possible for established and early-stage investigators. PMID:21868577

Shurin, Susan B

2011-11-17

126

Childhood overweight and cardiovascular disease risk factors: The National Heart, Lung, and Blood Institute Growth and Health Study  

PubMed Central

Objective To estimate the prevalence and incidence of overweight in black and white girls, and to examine associations between adolescent overweight and cardiovascular disease (CVD) risk factors. Study design In the National Heart, Lung, and Blood Institute Growth and Health Study (NGHS), annual measurements were obtained from girls followed longitudinally between the ages of 9 or 10 and 18; self-reported measures were obtained at ages 21-23. Participants were 1,166 white and 1,213 black girls. Childhood overweight as defined by the Centers for Disease Control and Prevention (CDC) was the independent variable of primary interest. Measured outcomes included blood pressure and lipid levels. Results Rates of overweight increased through adolescence from 7% to 10% in white girls and 17% to 24% in black girls. Incidence of overweight was greater during ages 9-12 than in later adolescence. Girls who were overweight during childhood were 11 to 30 times more likely to be obese in young adulthood. Overweight was significantly associated with increased percent body fat, sum of skinfolds and waist circumference, unhealthful systolic and diastolic blood pressure, HDL cholesterol and triglycerides. Conclusion The relationship between CVD risk factors and CDC-defined overweight is present at age 9. PMID:17188606

Thompson, Douglas R.; Obarzanek, Eva; Franko, Debra L.; Barton, Bruce A.; Morrison, John; Biro, Frank M.; Daniels, Stephen R.; Striegel-Moore, Ruth H.

2007-01-01

127

The role of the lung microbiome in health and disease. A National Heart, Lung, and Blood Institute workshop report.  

PubMed

Study of the human lung microbiome in the context of pulmonary health and disease is an area of emerging research interest that is being driven by several contributing factors. These factors include increased recognition of the diversity of human-associated microbiota, their roles in health and in diseases associated with chronic inflammation, and advancements in technologies and tools that have facilitated such discoveries about the microbiota in organ systems outside of the lung. Therefore, the overarching goals of lung microbiome research are: to identify and characterize microbial populations associated with the respiratory tract and lungs; to understand their roles in lung health and disease; and, we hope, to allow the development of improved approaches for diagnosing and treating chronic respiratory diseases in which the microbiome has a role. Recent studies of the lung microbiome have yielded a number of interesting findings but also highlighted questions and challenges for researchers and clinicians. In December 2011, the National Heart, Lung, and Blood Institute convened a workshop to identify key issues and areas for further attention or development to advance research on the lung microbiome. Current knowledge and the state of research on the lung and related areas of human microbiome investigation were reviewed and discussed. PMID:23614695

Huang, Yvonne J; Charlson, Emily S; Collman, Ronald G; Colombini-Hatch, Sandra; Martinez, Fernando D; Senior, Robert M

2013-06-15

128

Matrix biology of idiopathic pulmonary fibrosis: a workshop report of the national heart, lung, and blood institute.  

PubMed

A hallmark of idiopathic pulmonary fibrosis (IPF) is excessive and disordered deposition of extracellular matrix. Although the lung extracellular matrix normally plays an essential role in development and maintenance of lung tissue through reciprocal interactions with resident cells, the disordered matrix in the diseased lung is increasingly recognized as an active and important contributor to IPF pathogenesis. This working group summary from a recently conducted National Heart, Lung, and Blood Institute strategic planning workshop for IPF research highlights recent advances, challenges, and opportunities in the study of matrix biology in IPF. Particular attention is given to the composition and mechanical properties of the matrix in normal and diseased lungs, and the biochemical and biomechanical influences exerted by pathological matrix. Recently developed model systems are also summarized as key tools for advancing our understanding of matrix biology in IPF. Emerging approaches to therapeutically target the matrix in preclinical and clinical settings are discussed, as are important concepts, such as alterations of the matrix with aging and the potential for the resolution of fibrosis. Specific recommendations for future studies in matrix biology of IPF are also proposed. PMID:24726499

Thannickal, Victor J; Henke, Craig A; Horowitz, Jeffrey C; Noble, Paul W; Roman, Jesse; Sime, Patricia J; Zhou, Yong; Wells, Rebecca G; White, Eric S; Tschumperlin, Daniel J

2014-06-01

129

Registry of the Japanese Society of Lung and Heart-Lung Transplantation: official Japanese lung transplantation report, 2014.  

PubMed

The number of organ donations after brain death has significantly increased since the revised Japanese Organ Transplant Law took effect in July 2010. Sixty-one lung transplantations were conducted throughout Japan in 2013, including 20 living-donor lung transplantations and 41 brain-dead-donor lung transplantations (23 bilateral lungs, 17 single lungs, and 1 heart-lung transplantation). The number of lung transplant candidates newly registered at the Japan Organ Transplantation Network also increased to 126 in 2013, suggesting a severe donor shortage in Japan. More than 60 % of offered brain-dead-donor, lungs were used for transplantation, indicating the effort of Japanese lung transplant centers to overcome the challenge of donor shortage. After lung transplantation, patients generally enjoyed a good quality of life with excellent survival of 86.2 % at 1 year, 79.6 % at 3 years, and 73.7 % at 5 years post-transplantation. There was no significant difference in patient survival between living-donor and brain-dead-donor lung transplantation. Early mortality of lung transplant recipients within 90 days was attributable to graft failure followed by infection, while long-term mortality was mostly explained by chronic lung allograft dysfunction (chronic rejection), infection, and malignancy. Eight lung transplant centers are currently approved to conduct lung transplantation in Japan (Tohoku, Dokkyo, Chiba, Kyoto, Osaka, Okayama, Fukuoka, and Nagasaki Universities). These centers are expected to continue to make a special effort to save critically ill patients waiting for lung transplantation. PMID:24842125

Sato, Masaaki; Okada, Yoshinori; Oto, Takahiro; Minami, Masato; Shiraishi, Takeshi; Nagayasu, Takeshi; Yoshino, Ichiro; Chida, Masayuki; Okumura, Meinoshin; Date, Hiroshi; Miyoshi, Shinichiro; Kondo, Takashi

2014-10-01

130

Funding mechanisms and program management at the National Heart, Lung, and Blood Institute: confronting new challenges and exploring new opportunities  

PubMed Central

Over the past 8 years, the National Institutes of Health (NIH) budget appropriation has lost purchasing power, with erosion of the benefits of the doubling of the budget less than a decade ago. For the first time in 40 years, the NIH appropriation in fiscal year 2011 was 1% less than in the previous year. The National Heart, Lung, and Blood Institute (NHLBI) has been closely managing its funds to protect its core functions: support and conduct of research, and training of biomedical research scientists. Rigorous evaluations of funding mechanisms, management of clinical studies, set-aside programs and funding guidelines are designed to help the Institute, in consultation with its advisory council, to minimize the long-term impact of extreme resource limitations on the advance and conduct of science. This report describes some recent actions taken by the NHLBI to maximize support for investigator-initiated research, maintain a balanced portfolio, and provide as much support as possible for established and early-stage investigators. PMID:21868577

2011-01-01

131

Amelioratory effect of Andrographis paniculata Nees on liver, kidney, heart, lung and spleen during nicotine induced oxidative stress.  

PubMed

The ameliorative properties of bioactive compound andrographolide (ANDRO), aqueous extract of Andrographis paniculata (AE-AP) and vitamin E (vit.E) were tested against nicotine induced liver, kidney, heart, lung and spleen toxicity. A group of male Wistar rats were intraperitoneally administered vehicle, nicotine (1mg/kg body weight/day), nicotine+ANDRO (250mg/kg body weight/day), nicotine+AE-AP (250mg/kg body weight/day) and nicotine+vit.E (50mg/kg body weight/day) for the period of 7 days. The significantly increased levels of lipid peroxidation, protein oxidation and the decreased antioxidant enzyme status were noted in nicotine treated group as compared to vehicle treated group. ANDRO, AE-AP and vit.E significantly reduced the lipid peroxidation, protein oxidation and increased the antioxidant enzyme status. This indicates A. paniculata and vit.E may act as putative protective agent against nicotine induced tissue injury and may pave a new path to develop suitable drug therapy. PMID:21783869

Neogy, Sreeparna; Das, Subhasis; Mahapatra, Santanu Kar; Mandal, Nirjal; Roy, Somenath

2008-05-01

132

Chocolate Consumption is Inversely Associated with Prevalent Coronary Heart Disease: The National Heart, Lung, and Blood Institute Family Heart Study  

PubMed Central

Background and Aims Epidemiologic studies have suggested beneficial effects of flavonoids on cardiovascular disease. Cocoa and particularly dark chocolate are rich in flavonoids and recent studies have demonstrated blood pressure lowering effects of dark chocolate. However, limited data are available on the association of chocolate consumption and the risk of coronary heart disease (CHD). We sought to examine the association between chocolate consumption and prevalent CHD. Methods We studied in a cross-sectional design 4,970 participants aged 25 to 93 years who participated in the National Heart, Lung, and Blood Institute (NHLBI) Family Heart Study. Chocolate intake was assessed through a semi-quantitative food frequency questionnaire. We used generalized estimating equations to estimate adjusted odds ratios. Results Compared to subjects who did not report any chocolate intake, odds ratios (95% CI) for CHD were 1.01 (0.76-1.37), 0.74 (0.56-0.98), and 0.43 (0.28-0.67) for subjects consuming 1-3 times/month, 1-4 times/week, and 5+ times/week, respectively (p for trend <0.0001) adjusting for age, sex, family CHD risk group, energy intake, education, non-chocolate candy intake, linolenic acid intake, smoking, alcohol intake, exercise, and fruit and vegetables. Consumption of non-chocolate candy was associated with a 49% higher prevalence of CHD comparing 5+/week vs. 0/week [OR=1.49 (0.96-2.32)]. Conclusions These data suggest that consumption of chocolate is inversely related with prevalent CHD in a general population. PMID:20858571

Djousse, Luc; Hopkins, Paul N.; North, Kari E.; Pankow, James S.; Arnett, Donna K.; Ellison, R. Curtis

2010-01-01

133

Effects of N-Acetylcysteine on Nicotinamide Dinucleotide Phosphate Oxidase Activation and Antioxidant Status in Heart, Lung, Liver and Kidney in Streptozotocin-Induced Diabetic Rats  

PubMed Central

Purpose Hyperglycemia increases reactive oxygen species (ROS) and the resulting oxidative stress plays a key role in the pathogenesis of diabetic complications. Nicotinamide dinucleotide phosphate (NADPH) oxidase is one of the major sources of ROS production in diabetes. We, therefore, examined the possibility that NADPH oxidase activation is increased in various tissues, and that the antioxidant N-acetylcysteine (NAC) may have tissue specific effects on NADPH oxidase and tissue antioxidant status in diabetes. Materials and Methods Control (C) and streptozotocin-induced diabetic (D) rats were treated either with NAC (1.5 g/kg/day) orally or placebo for 4 weeks. The plasma, heart, lung, liver, kidney were harvested immediately and stored for biochemical or immunoblot analysis. Results levels of free 15-F2t-isoprostane were increased in plasma, heart, lung, liver and kidney tissues in diabetic rats, accompanied with significantly increased membrane translocation of the NADPH oxidase subunit p67phox in all tissues and increased expression of the membrane-bound subunit p22phox in heart, lung and kidney. The tissue antioxidant activity in lung, liver and kidney was decreased in diabetic rats, while it was increased in heart tissue. NAC reduced the expression of p22phox and p67phox, suppressed p67phox membrane translocation, and reduced free 15-F2t-isoprostane levels in all tissues. NAC increased antioxidant activity in liver and lung, but did not significantly affect antioxidant activity in heart and kidney. Conclusion The current study shows that NAC inhibits NADPH oxidase activation in diabetes and attenuates tissue oxidative damage in all organs, even though its effects on antioxidant activity are tissue specific. PMID:22318816

Lei, Shaoqing; Liu, Yanan; Liu, Huimin; Yu, Hong; Wang, Hui

2012-01-01

134

Future directions for cardiovascular disease comparative effectiveness research: report of a workshop sponsored by the National Heart, Lung, and Blood Institute.  

PubMed

Comparative effectiveness research (CER) aims to provide decision makers with the evidence needed to evaluate the benefits and harms of alternative clinical management strategies. CER has become a national priority, with considerable new research funding allocated. Cardiovascular disease is a priority area for CER. This workshop report provides an overview of CER methods, with an emphasis on practical clinical trials and observational treatment comparisons. The report also details recommendations to the National Heart, Lung, and Blood Institute for a new framework for evidence development to foster cardiovascular CER, and specific studies to address 8 clinical issues identified by the Institute of Medicine as high priorities for cardiovascular CER. PMID:22796257

Hlatky, Mark A; Douglas, Pamela S; Cook, Nakela L; Wells, Barbara; Benjamin, Emelia J; Dickersin, Kay; Goff, David C; Hirsch, Alan T; Hylek, Elaine M; Peterson, Eric D; Roger, Véronique L; Selby, Joseph V; Udelson, James E; Lauer, Michael S

2012-08-14

135

Are central institutional review boards the solution? The National Heart, Lung, and Blood Institute Working Group's report on optimizing the IRB process.  

PubMed

The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health convened a working group in June 2011 to examine alternative institutional review board (IRB) models. The working group was held in response to proposed changes in the regulations for government-supported research and the proliferation of multicenter clinical trials where multiple individual reviews may be inefficient. Group members included experts in heart, lung, and blood research, research oversight, bioethics, health economics, regulations, and information technology (IT). The group discussed alternative IRB models, ethical concerns, metrics for evaluating IRBs, IT needs, and economic considerations. Participants noted research gaps in IRB best practices and in metrics. The group arrived at recommendations for process changes, such as defining specific IRB performance requirements in funding announcements, requiring funded researchers to use more efficient alternative IRB models, and developing IT systems to facilitate information sharing and collaboration among IRBs. Despite the success of the National Cancer Institute's central IRB (CIRB), the working group, concerned about the creation costs and unknown cost-efficiency of a new CIRB, and about the risk of shifting the burden of dealing with multiple IRBs from sponsors to research institutions, did not recommend the creation of an NHLBI-funded CIRB. PMID:23095928

Mascette, Alice M; Bernard, Gordon R; Dimichele, Donna; Goldner, Jesse A; Harrington, Robert; Harris, Paul A; Leeds, Hilary S; Pearson, Thomas A; Ramsey, Bonnie; Wagner, Todd H

2012-12-01

136

The role of cryotherapy for airway complications after lung and heart–lung transplantation 1 Presented at the 10th Annual Meeting of the European Association for Cardiothoracic Surgery, Prague, Czech Republic, 6–9 October, 1996. 1  

Microsoft Academic Search

Objective: Although airway problems after lung and heart–lung transplantation have been greatly reduced due to changes in surgical technique, excessive granulation tissue at the anastomosis may threaten airway patency. Treatment options include electrocautery, dilation, laser coagulation and stent placement however, recurrence remains a problem. Cryotherapy, the controlled application of extreme cold, is effective at causing cell lysis in granulation tissue

M. O. Maiwand; K. J. Zehr; C. M. Dyke; M. Peralta; S. Tadjkarimi; A. Khagani; M. H. Yacoub

1997-01-01

137

The Summer Institutes for Training in Biostatistics are sponsored by the National Heart, Lung, and Blood Institute (http://www.nhlbi.nih.gov/funding/training/redbook/sibsweb.htm) and the National Center for Research Resources.  

E-print Network

The Summer Institutes for Training in Biostatistics are sponsored by the National Heart, Lung IN BIOSTATISTICS (SIBS) Attention all mathematics, statistics, and science students seeking a summer opportunity The opportunity to learn the principles of applied biostatistics from recognized experts in the field and meet

Karsai, Istvan

138

The Summer Institutes for Training in Biostatistics are sponsored by the National Heart, Lung, and Blood Institute (http://www.nhlbi.nih.gov/funding/training/redbook/sibsweb.htm) and the National Center for Research Resources.  

E-print Network

The Summer Institutes for Training in Biostatistics are sponsored by the National Heart, Lung IN BIOSTATISTICS (SIBS) Attention all mathematics, statistics, and science students seeking a summer opportunity the principles of applied biostatistics from recognized experts in the field and meet practicing biostatisticians

Wisconsin at Madison, University of

139

Comparison of in-hospital and one-year outcomes in patients with and without diabetes mellitus undergoing percutaneous catheter intervention (from the National Heart, Lung, and Blood Institute Dynamic Registry)  

Microsoft Academic Search

Extrapolation of improvements in percutaneous coronary intervention (PCI) and outcomes to patients with diabetes has not been systematically examined in clinical practice. Two waves of consecutive patients (n = 4,629) who underwent PCI from July 1997 to June 1999 enrolled in the National Heart, Lung, and Blood Institute Dynamic Registry comprise the study population. There were 1,058 patients with treated

Warren K Laskey; Faith Selzer; Helen A Vlachos; Janet Johnston; Alice Jacobs; Spencer B King; David R Holmes; John Douglas; Peter Block; Robert Wilensky; David O Williams; Katherine Detre

2002-01-01

140

Pantoea agglomerans pneumonia in a heart-lung transplant recipient: case report and a review of an emerging pathogen in immunocompromised hosts.  

PubMed

Pantoea agglomerans is a gram-negative rod that is frequently found on the exterior of many plants, fruits, vegetables, and in soil, and it is used as a biopesticide in the agriculture industry. Recent reports have implicated P. agglomerans in systemic infections of immunocompromised hosts and neonates, as well as more localized infections in healthy hosts. P. agglomerans as a cause of hospital-acquired pneumonia has not been well characterized. We report a case of P. agglomerans pneumonia in a heart-lung transplant recipient following transplantation. The organism was susceptible to multiple antimicrobial agents and treated successfully with ertapenem. We review the patient's course and the relevant literature, and discuss implications for the future. PMID:21504526

Shubov, A; Jagannathan, P; Chin-Hong, P V

2011-10-01

141

Lung and heart-lung transplantation for systemic sclerosis patients. A monocentric experience of 13 patients, review of the literature and position paper of a multidisciplinary Working Group.  

PubMed

Systemic sclerosis per se should not be considered as an a priori contraindication for a pre-transplantation assessment in patients with advanced interstitial lung disease and/or pulmonary hypertension. For lung or heart-lung transplantation, a multidisciplinary approach, adapting the pre-transplant assessment to systemic sclerosis and optimizing systemic sclerosis patient management before, during and after surgery should improved the short- and long-term prognosis. Indications and contraindications for transplantation have to be adapted to the specificities of systemic sclerosis. A special focus on the digestive tract involvement and its thorough evaluation are mandatory before transplantation in systemic sclerosis. As the esophagus is almost always involved, isolated gastro-oesophageal reflux disease, pH metry and/or manometry abnormalities should not be a systematic per se contraindication for pre-transplantation assessment. Corticosteroids may be harmful in systemic sclerosis as they are associated with acute renal crisis. A low dose corticosteroids protocol for immunosuppression is therefore advisable in systemic sclerosis. PMID:25027464

Launay, David; Savale, Laurent; Berezne, Alice; Le Pavec, Jérôme; Hachulla, Eric; Mouthon, Luc; Sitbon, Olivier; Lambert, Benoit; Gaudric, Marianne; Jais, Xavier; Stephan, Francois; Hatron, Pierre-Yves; Lamblin, Nicolas; Vignaux, Olivier; Cottin, Vincent; Farge, Dominique; Wallaert, Benoît; Guillevin, Loic; Simonneau, Gerald; Mercier, Olaf; Fadel, Elie; Dartevelle, Philippe; Humbert, Marc; Mussot, Sacha

2014-10-01

142

Kid Machine  

NSDL National Science Digital Library

This activity is on page 3 (continued on page 2) of the pdf, part of the Simple Machines Discovery Box. In this fun activity, learners "create" a complex machine by simulating the parts in action. Learners move their bodies and make sounds as if they are individual parts of a moving machine. Then learners discover what happens when part of a machine is broken and problem solve ways to fix it.

Omsi

2004-01-01

143

Quantum Machines  

E-print Network

We discuss quantum information processing machines. We start with single purpose machines that either redistribute quantum information or identify quantum states. We then move on to machines that can perform a number of functions, with the function they perform being determined by a program, which is itself a quantum state. Examples of both deterministic and probabilistic programmable machines are given, and we conclude with a discussion of the utility of quantum programs.

Mark Hillery; Vladimir Buzek

2009-03-24

144

Mining machine  

Microsoft Academic Search

A haulage system for a mining machine comprises a mining machine mounted on and\\/or guided by a conveyor and reciprocable with respect thereto, the conveyor being provided with a rack having plural rows of teeth of identical pitch, with the teeth of one row staggered with respect to an adjacent row(s), and the machine being provided with at least one

Parrott

1985-01-01

145

[Improving of muscle mass and force in rehabilitation of heart-lung patients. Aerobic interval training, resistance-exercises, excentric exercises, vibration].  

PubMed

Improvement of muscle mass and force which got depleted by inactivity or pathological processes is one of the aims and also a prerequisite of a rehabilitative intervention. Metabolically active larger and stronger muscles diminish the cardiovascular risk, permit the aerobic preventive and rehabilitative activities and enables a higher quality of life. Interval forms of aerobic exercise improves also the muscles. The resistance training plays an important part in rehabilitation. Beside the traditional dynamic strength training with weights, gym machines, body weight etc. the excentric type of muscle activity potentiates higher muscle load with lesser energy consumption, therefore it is suitable in the case of smaller performance ability. Vibration of the whole body or parts of it by machines improves the co-activity of the motor units and results in force development with small metabolic involvement. PMID:16238250

Apor, Péter; Tihanyi, József; Borka, Péter

2005-09-18

146

Kicking Machine  

NSDL National Science Digital Library

In this design challenge activity, learners build a machine that kicks a Ping-Pong ball into a cup lying on its side 12 inches away. Learners use a pendulum, a rubber band, or a combination of the two to do this and test the accuracy of their machines by shooting a Ping-Pong ball into a cup. Educators can use this activity to demonstrate simple machines and kinetic/potential energy. This activity can be followed up with "Extreme Kicking Machine" which adds an even greater challenge into the mix.

Wgbh

2010-01-01

147

: Helmholtz machine estimation .  

E-print Network

: Helmholtz machine density estimation . . : . . . (supervised learning) , (active learning) (query learning) [1, 3]. . (unsupervised learning), . , [5]. . Helmholtz machine , . Helmholtz machine : Helmholtz machine [2] . Helmholtz machine (generative network) (recognition network) . , , . Helmholtz machine (self

148

Nonplanar machines  

SciTech Connect

This talk examines methods available to minimize, but never entirely eliminate, degradation of machine performance caused by terrain following. Breaking of planar machine symmetry for engineering convenience and/or monetary savings must be balanced against small performance degradation, and can only be decided on a case-by-case basis. 5 refs.

Ritson, D. (Stanford Linear Accelerator Center, Menlo Park, CA (USA))

1989-05-01

149

Electric machine  

DOEpatents

An interior permanent magnet electric machine is disclosed. The interior permanent magnet electric machine comprises a rotor comprising a plurality of radially placed magnets each having a proximal end and a distal end, wherein each magnet comprises a plurality of magnetic segments and at least one magnetic segment towards the distal end comprises a high resistivity magnetic material.

El-Refaie, Ayman Mohamed Fawzi (Niskayuna, NY); Reddy, Patel Bhageerath (Madison, WI)

2012-07-17

150

Simple Machines  

NSDL National Science Digital Library

How do you get a glove and a ball up to your tree house? One answer is to use a pulley. A pulley is a simple machine. In this original KET interactive, children learn about the basic workings of three simple machines.

Ket

2010-11-16

151

Excavating machines  

SciTech Connect

The excavating machine has a cutter carrying boom carried by a boom support member which can be swung about an axis extending in the direction of the roadway. The machine includes a cutter unit and a stay unit each of which is releasably anchorable in the roadway and each of which can be advanced relative to the other unit.

Plummer, D.

1980-10-21

152

Scribbling Machines  

NSDL National Science Digital Library

In this activity, learners explore electronics and motion by making a Scribbling Machine, a motorized contraption that moves in unusual ways and leaves a mark to trace its path. Itâs made from simple materials and is based on the idea of motion created by an offset motor. Try using harvested motors and switches from discarded toys and electronics to make your Scribbling Machine - this not only keeps costs down, but is a playful and inventive way to explore how everyday objects work. To take the activity further, you can also incorporate PicoCrickets to make your Scribbling Machine more intelligent and to explore computers.

Exploratorium

2013-01-30

153

Machine therapy  

E-print Network

Machine Therapy is a new practice combining art, design, psychoanalysis, and engineering work in ways that access and reveal the vital, though often unnoticed, relevance of people's interactions and relationships with ...

Dobson, Kelly E. (Kelly Elizabeth), 1970-

2007-01-01

154

Math Machines  

NSDL National Science Digital Library

The mission of the Math Machines organization is to "improve the quality of mathematical education, enhance the transfer of mathematical thinking into other classes, and increase students' ability to apply rigorous mathematics outside the classroom." Their website supports a National Science Foundation ATE grant-supported project designed to improve teaching in the areas of Mathematics, Science, and Technology at the high school and college levels. This improved learning results from using math, science, and technology principles to build and control various machines such as pointers and robots or "math machines", which are simple devices that provide an immediate, physical, dynamic expression to abstract mathematical equations. The website provides information links on Educational Theory, Classroom Activities, Project Workshops, Calculators & Programs, and Machine Construction Instructions for Building: Closed Circuits, Servo Motors, Controllers, Robot Boards and more. There is also contact information, an FAQ section, as well as upcoming events.

2010-05-18

155

Monel Machining  

NASA Technical Reports Server (NTRS)

Castle Industries, Inc. is a small machine shop manufacturing replacement plumbing repair parts, such as faucet, tub and ballcock seats. Therese Castley, president of Castle decided to introduce Monel because it offered a chance to improve competitiveness and expand the product line. Before expanding, Castley sought NERAC assistance on Monel technology. NERAC (New England Research Application Center) provided an information package which proved very helpful. The NASA database was included in NERAC's search and yielded a wealth of information on machining Monel.

1983-01-01

156

Workout Machine  

NASA Technical Reports Server (NTRS)

The Orbotron is a tri-axle exercise machine patterned after a NASA training simulator for astronaut orientation in the microgravity of space. It has three orbiting rings corresponding to roll, pitch and yaw. The user is in the middle of the inner ring with the stomach remaining in the center of all axes, eliminating dizziness. Human power starts the rings spinning, unlike the NASA air-powered system. Marketed by Fantasy Factory (formerly Orbotron, Inc.), the machine can improve aerobic capacity, strength and endurance in five to seven minute workouts.

1995-01-01

157

Culture Machine  

NSDL National Science Digital Library

Culture Machine is a new, refereed, electronic journal encompassing cultural studies and cultural theory. The international editorial board of the interactive journal aims to "generat[e] research in culture and theory" by promoting and publishing "the most provocative of new work." The theme of the inaugural issue is Taking Risks with the Future. Content includes articles such as Life After Death of the Text by Johan Fornas, Cultural Studies in the Clouds: Mourning for Detail by Tadeusz Slawek, and The Future States of Politics by Kenneth Surin. Culture Machine is hosted by the University of Teesside, England.

158

Simulating Turing Machines on Maurer Machines  

E-print Network

Simulating Turing Machines on Maurer Machines J.A. Bergstra1,2 and C.A. Middelburg3 1 Programming MB Eindhoven, the Netherlands keesm@win.tue.nl Abstract. Maurer machines are much closer to real computers than Turing machines. Computer instructions play a prominent part in Mau- rer machines. We show

van der Zwaag, Mark

159

Decoding Machine  

NSDL National Science Digital Library

In this math lesson, learners explore variables and their uses. Learners pretend to be FBI agents and make a TOP SECRET tool that enables them to decode and find the values of hidden messages and words. Learners make their simple "decoding machines" out of paper and tape.

Lessonplans, Utah

2012-10-22

160

Leonardo's Machines  

NSDL National Science Digital Library

This Science NetLinks lesson will highlight some of Leonardo da Vinci's futuristic inventions, introducing the elements of machines. Through the use of student interactives, this lesson provides an interesting context in which students can begin to develop their ideas about the uniqueness of humans in the natural world.

Science Netlinks;

2003-03-05

161

Function Machine  

NSDL National Science Digital Library

This Java applet allows learners to explore simple linear functions. Students determine the algebraic form of a linear equation by entering inputs into the machine and by looking for patterns in the outputs. The function rules available are: integers from -10 to 10 are either added to, subtracted from, or multiplied by the input x to yield the output y.

2011-01-01

162

Drilling Machines: Vocational Machine Shop.  

ERIC Educational Resources Information Center

The lessons and supportive information in this field tested instructional block provide a guide for teachers in developing a machine shop course of study in drilling. The document is comprised of operation sheets, information sheets, and transparency masters for 23 lessons. Each lesson plan includes a performance objective, material and tools,…

Thomas, John C.

163

Machine Learning  

NASA Astrophysics Data System (ADS)

The purpose of this chapter is to present fundamental ideas and techniques of machine learning suitable for the field of this book, i.e., for automated scientific discovery. The chapter focuses on those symbolic machine learning methods, which produce results that are suitable to be interpreted and understood by humans. This is particularly important in the context of automated scientific discovery as the scientific theories to be produced by machines are usually meant to be interpreted by humans. This chapter contains some of the most influential ideas and concepts in machine learning research to give the reader a basic insight into the field. After the introduction in Sect. 1, general ideas of how learning problems can be framed are given in Sect. 2. The section provides useful perspectives to better understand what learning algorithms actually do. Section 3 presents the Version space model which is an early learning algorithm as well as a conceptual framework, that provides important insight into the general mechanisms behind most learning algorithms. In section 4, a family of learning algorithms, the AQ family for learning classification rules is presented. The AQ family belongs to the early approaches in machine learning. The next, Sect. 5 presents the basic principles of decision tree learners. Decision tree learners belong to the most influential class of inductive learning algorithms today. Finally, a more recent group of learning systems are presented in Sect. 6, which learn relational concepts within the framework of logic programming. This is a particularly interesting group of learning systems since the framework allows also to incorporate background knowledge which may assist in generalisation. Section 7 discusses Association Rules - a technique that comes from the related field of Data mining. Section 8 presents the basic idea of the Naive Bayesian Classifier. While this is a very popular learning technique, the learning result is not well suited for human comprehension as it is essentially a large collection of probability values. In Sect. 9, we present a generic method for improving accuracy of a given learner by generatingmultiple classifiers using variations of the training data. While this works well in most cases, the resulting classifiers have significantly increased complexity and, hence, tend to destroy the human readability of the learning result that a single learner may produce. Section 10 contains a summary, mentions briefly other techniques not discussed in this chapter and presents outlook on the potential of machine learning in the future.

Hoffmann, Achim; Mahidadia, Ashesh

164

Fullerene Machines  

NASA Technical Reports Server (NTRS)

Fullerenes possess remarkable properties and many investigators have examined the mechanical, electronic and other characteristics of carbon SP2 systems in some detail. In addition, C-60 can be functionalized with many classes of molecular fragments and we may expect the caps of carbon nanotubes to have a similar chemistry. Finally, carbon nanotubes have been attached to t he end of scanning probe microscope (Spill) tips. Spills can be manipulated with sub-angstrom accuracy. Together, these investigations suggest that complex molecular machines made of fullerenes may someday be created and manipulated with very high accuracy. We have studied some such systems computationally (primarily functionalized carbon nanotube gears and computer components). If such machines can be combined appropriately, a class of materials may be created that can sense their environment, calculate a response, and act. The implications of such hypothetical materials are substantial.

Globus, Al; Saini, Subhash (Technical Monitor)

1998-01-01

165

Fullerene Machines  

NASA Technical Reports Server (NTRS)

Recent computational efforts at NASA Ames Research Center and computation and experiment elsewhere suggest that a nanotechnology of machine phase functionalized fullerenes may be synthetically accessible and of great interest. We have computationally demonstrated that molecular gears fashioned from (14,0) single-walled carbon nanotubes and benzyne teeth should operate well at 50-100 gigahertz. Preliminary results suggest that these gears can be cooled by a helium atmosphere and a laser motor can power fullerene gears if a positive and negative charge have been added to form a dipole. In addition, we have unproven concepts based on experimental and computational evidence for support structures, computer control, a system architecture, a variety of components, and manufacture. Combining fullerene machines with the remarkable mechanical properties of carbon nanotubes, there is some reason to believe that a focused effort to develop fullerene nanotechnology could yield materials with tremendous properties.

Globus, Al; Saini, Subhash

1998-01-01

166

Simple Machines  

NSDL National Science Digital Library

Can you identify the six types of simple machines? 1. What do you know about Inclined Planes? Draw an example on your graphic organizer and state one fact.Inclined Plane 2. What do you know about levers? Draw an example on your graphic organizer and state one fact.Lever. 3. What do you know about pulleys? Draw an example on your graphic organizer and ...

Stewart, Miss

2010-03-24

167

Induction machine  

DOEpatents

A polyphase rotary induction machine for use as a motor or generator utilizing a single rotor assembly having two series connected sets of rotor windings, a first stator winding disposed around the first rotor winding and means for controlling the current induced in one set of the rotor windings compared to the current induced in the other set of the rotor windings. The rotor windings may be wound rotor windings or squirrel cage windings.

Owen, Whitney H. (Ogden, UT)

1980-01-01

168

A Generalized Deletion Machine  

E-print Network

In this work we prescribe a more generalized quantum-deleting machine (input state dependent). The fidelity of deletion is dependent on some machine parameters such that on alteration of machine parameters we get back to standard deleting machines. We also carried out a various comparative study of various kinds of quantum deleting machines. We also plotted graphs, making a comparative study of fidelity of deletion of the deletion machines, obtained as particular cases on changing the machine parameters of our machine.

Indranil Chakrabarty; Satyabrata Adhikari

2005-11-22

169

State-Machine Replication  

E-print Network

State-Machine Replication #12;The Problem Clients Server #12;The Problem Clients Server #12;The (state machine) #12;The Solution 1. Make server deterministic (state machine) State machine #12;The Solution 1. Make server deterministic (state machine) 2. Replicate server State machines #12;The Solution 1

Venkataramani, Arun

170

Machine Design  

NSDL National Science Digital Library

This website, the homepage of Machine Design.com, contains resources on a variety of information for engineers and technicians related to devices, components, design applications, products, and systems in the manufacturing technology sector. The site also features a CAD library, eBooks, audiovisual aids, webinars, whitepapers and a reference center. Some of the resources require a free login. The page offers an RSS feed to keep users up to date on new resources. A free login may be required to access some of these items.

2009-11-09

171

Function Machine  

NSDL National Science Digital Library

This Java activity for the interactive white board (free access with registration) provides learners an opportunity to explore number functions and to predict outcomes. Teachers set the desired function from the drop-down list (double it, halve it, add 1, subtract 1, add 10, or subtract 10) and choose the start number from 1-20. Students are asked to predict the outcome before asking the machine to go. There is an option to hide the function so the teacher can ask students to work out what operation is being used to get from the starting number to the number generated.

2012-07-19

172

National Heart, Lung, and Blood Institute  

E-print Network

pressure can lead to heart and kidney disease, stroke, and blindness. But high blood pressure can the brain to hemor- rhage or the kidneys to function poorly or not at all. If not controlled, high blood for at least 30 minutes on most days of the week. · If you drink alcoholic beverages, do so in moderation

Bandettini, Peter A.

173

National Heart, Lung, and Blood Institute  

E-print Network

, gallbladder disease, sleep apnea, and certain cancers. On the other hand, a healthy weight has many benefits focus on one thing: weight loss. However, if you set goals, eat healthy foods, and are physically active, then you may be more successful at losing weight. Weight Loss Goals Setting the right goals is an important

Bandettini, Peter A.

174

National Heart, Lung, and Blood Institute  

E-print Network

of death in the United States for both men and women. Carotid artery disease occurs when plaque builds up in the arteries may start in childhood. Certain traits, conditions, or habits raise your risk for atherosclerosis cholesterol levels · High blood pressure · Smoking · Insulin resistance · Diabetes · Overweight or obesity

Bandettini, Peter A.

175

National Heart, Lung, and Blood Institute  

E-print Network

heart disease (CHD), also called coronary artery disease, is the leading cause of death in the United States for both men and women. CHD occurs when plaque builds up inside the coronary arteries of plaque in the coronary arteries may start in childhood. Certain traits, conditions, or habits raise your

Bandettini, Peter A.

176

National Heart, Lung, and Blood Institute  

E-print Network

disease.) · High-densitylipoprotein(HDL,or"good") cholesterol--which helps keep cholesterol from building up in the arteries. An HDL of 60 mg/dL will help lower your risk for heart disease. (The higher your HDL cholesterol level, the lower your chance of getting heart disease.) · Triglycerides--another form

Bandettini, Peter A.

177

National Heart, Lung, and Blood Institute  

MedlinePLUS

... available. Inside NHLBI Featured Fact Sheet Green Fluorescent RNA Helps Reveal the Inner Workings of Living Cells ... called “Baby Spinach” could offer new insights in RNA’s role in cellular activity. Read full fact sheet... ...

178

Mind & Machine  

NSDL National Science Digital Library

Mind & Machine is a weekly column provided by Ashley Dunn for the New York Times Cybertimes that discusses topics related to computing, technology, and the Internet. Recent columns have addressed the topics of the development of Internet telephony, possible futures of user interfaces, the history of technology and standards, and the Internet as a vehicle for community. Articles are well written, opinionated, and thought provoking. Mr. Dunn is a free lance writer who has written for such papers as the New York Times, the Los Angeles Times, the Seattle Post-Intelligencer, and the South China Morning Post. Note that the site is available only upon registration and is free of charge only in the US.

Dunn, Ashley.

1996-01-01

179

Course info Machine Learning  

E-print Network

Course info Machine Learning Real life problems Lecture 1: Machine Learning Problem Qinfeng (Javen) Shi 28 July 2014 Intro. to Stats. Machine Learning COMP SCI 4401/7401 Qinfeng (Javen) Shi Lecture 1: Machine Learning Problem #12;Course info Machine Learning Real life problems Table of Contents I 1 Course

Shi, Qinfeng "Javen"

180

Capacitive on-line hematocrit sensor design based on impedance spectroscopy for use in hemodialysis machines.  

PubMed

This paper presents a new design for an on-line and in-line hematocrit (HCT) sensor. Special feature of the sensor is the capability to measure the hematocrit of a blood sample inside standard plastic tubing widely used in medical equipment. No blood sample has to be extracted out of existing extracorporeal blood circulation systems such as hemodialysis machines or heart-lung machines. The sensor principle is based on electrical impedance spectroscopy. Dielectric properties of the blood and the plastic tubing are measured at various frequencies. In order to optimize the sensitivity, a unique electrode configuration is developed and optimized by Finite Element Simulation. The new electrode design optimizes the overall sensitivity of the sensor towards a change in dielectric properties of the blood caused by the HCT value and therefore decreases the sensitivity to side effects caused by temperature drift and component tolerances. As a result of the optimized overall sensor performance the complexity of a sensor readout circuitry can be reduced to a minimum which leads to an unmatched price-performance ratio for a complete measurement system. PMID:19963491

Trebbels, Dennis; Hradetzky, David; Zengerle, Roland

2009-01-01

181

Socially guided machine learning  

E-print Network

Social interaction will be key to enabling robots and machines in general to learn new tasks from ordinary people (not experts in robotics or machine learning). Everyday people who need to teach their machines new things ...

Thomaz, Andrea Lockerd

2006-01-01

182

Machine musicianship  

NASA Astrophysics Data System (ADS)

The training of musicians begins by teaching basic musical concepts, a collection of knowledge commonly known as musicianship. Computer programs designed to implement musical skills (e.g., to make sense of what they hear, perform music expressively, or compose convincing pieces) can similarly benefit from access to a fundamental level of musicianship. Recent research in music cognition, artificial intelligence, and music theory has produced a repertoire of techniques that can make the behavior of computer programs more musical. Many of these were presented in a recently published book/CD-ROM entitled Machine Musicianship. For use in interactive music systems, we are interested in those which are fast enough to run in real time and that need only make reference to the material as it appears in sequence. This talk will review several applications that are able to identify the tonal center of musical material during performance. Beyond this specific task, the design of real-time algorithmic listening through the concurrent operation of several connected analyzers is examined. The presentation includes discussion of a library of C++ objects that can be combined to perform interactive listening and a demonstration of their capability.

Rowe, Robert

2002-05-01

183

Machines registres Yves Lafont  

E-print Network

Machines à registres Yves Lafont Université d'Aix-Marseille Institut de Mathématiques de Luminy) Pascal Turing Von Neumann #12;Quelle opération calcule cette machine ? Exemple 1 2 registres : (+ 1 Quelle opération calcule cette machine ? #12;Quelle propriété teste cette machine ? Exemple 3 1 seul

Lafont, Yves

184

Can Machines BeCan Machines Be Polite?Polite?  

E-print Network

Can Machines BeCan Machines Be Polite?Polite? Michael A. CovingtonMichael A. Covington Artificial Intelligence CenterArtificial Intelligence Center #12;Can machines be polite?Can machines be polite? Machines have beenMachines have been annoying peopleannoying people ever since humanever since human--machine

Covington, Michael A.

185

Hybrid Quantum Cloning Machine  

E-print Network

In this work, we introduce a special kind of quantum cloning machine called Hybrid quantum cloning machine. The introduced Hybrid quantum cloning machine or transformation is nothing but a combination of pre-existing quantum cloning transformations. In this sense it creates its own identity in the field of quantum cloners. Hybrid quantum cloning machine can be of two types: (i) State dependent and (ii) State independent or Universal. We study here the above two types of Hybrid quantum cloning machines. Later we will show that the state dependent hybrid quantum-cloning machine can be applied on only four input states. We will also find in this paper another asymmetric universal quantum cloning machine constructed from the combination of optimal universal B-H quantum cloning machine and universal anti-cloning machine. The fidelities of the two outputs are different and their values lie in the neighborhood of ${5/6} $

Satyabrata Adhikari; A. K. Pati; Indranil Chakrabarty; B. S. Choudhury

2007-05-04

186

Extreme Kicking Machine  

NSDL National Science Digital Library

In this design challenge activity follow up to "Kicking Machine", learners add a hands-free feature to their Kicking Machine. Learners modify their kicking machine to have it either release the pendulum or rubber band while standing three feet away or have it automatically feed balls into the kicking machine, one after another. They must figure out how to integrate the new feature into the existing structure and use the design process to make sure the modified kicking machine works properly. Educators can use this activity to demonstrate simple machines and kinetic/potential energy.

Wgbh

2010-01-01

187

Machine Learning for Global Optimization  

E-print Network

global optimization, machine learning, support vector machines, space trajectory design. Introduction ...... LIBSVM: a library for support vector machines. (Software ... Boston, Dordrecht, London: Kluwer Academic Publishers. Mangasarian, O. L. ...

schoen,,,

188

Interactive Gumball Machine  

NSDL National Science Digital Library

In this activity, learners review the history of gumball machines and explore potential and kinetic energy, while working in teams to build a gumball slide. Teams then design and build their own interactive gumball machine.

Ieee

2013-08-30

189

Your Sewing Machine.  

ERIC Educational Resources Information Center

The programed instruction manual is designed to aid the student in learning the parts, uses, and operation of the sewing machine. Drawings of sewing machine parts are presented, and space is provided for the student's written responses. Following an introductory section identifying sewing machine parts, the manual deals with each part and its…

Peacock, Marion E.

190

Talking Vending Machines  

E-print Network

're in the central Tokyo Station and you're thirsty so you go to the, you know, vending machine to buy a drink. Only this is not your average vending machine. Uh uh. This vending machine has opinions on what beverage you want. Sensors built into large touch panels...

Hacker, Randi

2011-02-02

191

Millikelvin Lab Machine Shop  

E-print Network

Millikelvin Lab OP105­112 Machine Shop OP132 Resistive Magnet Shop CICC Winding Area Transformers This building is home to the Millikelvin lab, the control room, the resistive magnet and machine shops, the CICC@magnet.fsu.edu (850) 644-4378 (850) 644-0534 2 MACHINE SHOP OP132 Vaughan Williams (A114*) williams

McQuade, D. Tyler

192

Cable-Twisting Machine  

NASA Technical Reports Server (NTRS)

New cable-twisting machine is smaller and faster than many production units. Is useful mainly in production of short-run special cables. Already-twisted cable can be fed along axis of machine. Faster operation than typical industrial cable-twisting machines possible by using smaller spools of wire.

Kurnett, S.

1982-01-01

193

Circular tests for HSM machine tools: Bore machining application  

Microsoft Academic Search

Today's High-Speed Machining (HSM) machine tool combines productivity and part quality. The difficulty inherent in HSM operations lies in understanding the impact of machine tool behaviour on machining time and part quality. Analysis of some of the relevant ISO standards [230. Acceptance code for machine tools. Part 4, Circular tests for numerically controlled machine-tools, April 1998, 10791. Test conditions for

Laurent Tapie; Kwamiwi Mawussi; Bernard Anselmetti

2007-01-01

194

What is Machine Learning? About the Course Example Machine Learning  

E-print Network

What is Machine Learning? About the Course Example Machine Learning DD2431 ¨Orjan Ekeberg Oct­Dec, 2008 #12;What is Machine Learning? About the Course Example 1 What is Machine Learning? Definition A Hypothetical Project #12;What is Machine Learning? About the Course Example 1 What is Machine Learning

Kjellström, Hedvig

195

What is Machine Learning? About the Course Example Machine Learning  

E-print Network

What is Machine Learning? About the Course Example Machine Learning DD2431 ¨Orjan Ekeberg Oct­Dec, 2007 What is Machine Learning? About the Course Example 1 What is Machine Learning? Definition A Hypothetical Project What is Machine Learning? About the Course Example 1 What is Machine Learning? Definition

Kjellström, Hedvig

196

What is Machine Learning? About the Course Example Machine Learning  

E-print Network

What is Machine Learning? About the Course Example Machine Learning DD2431 ¨Orjan Ekeberg Oct­Dec, 2008 What is Machine Learning? About the Course Example 1 What is Machine Learning? Definition A Hypothetical Project What is Machine Learning? About the Course Example 1 What is Machine Learning? Definition

Kjellström, Hedvig

197

What is Machine Learning? About the Course Example Machine Learning  

E-print Network

What is Machine Learning? About the Course Example Machine Learning DD2431 ¨Orjan Ekeberg Oct­Dec, 2007 #12;What is Machine Learning? About the Course Example 1 What is Machine Learning? Definition A Hypothetical Project #12;What is Machine Learning? About the Course Example 1 What is Machine Learning

Kjellström, Hedvig

198

Benchmarking the Connection Machine  

SciTech Connect

The purpose of this memo is to present the results of work done recently on the Connection Machine during a one-week visit by the authors to Thinking Machines Corporation. The main objectives of the trip were to benchmark the Connection Machine and to assess the software environment, in order to determine the suitability of the Connection Machine for solving computationally-intensive problems and to compare the Connection Machine with other highly-parallel computers. This report presents preliminary results, and describes the computer architecture.

Baillie, C.; Felten, E.; Walker, D.

1987-01-01

199

Edheads: The Compound Machine  

NSDL National Science Digital Library

This resource is a collection of interactive animations designed to help kids learn how forces and simple machines can work together to create the compound machine. Child-centered animated activities enhance understanding of how compound machines function and how they are differentiated from simple machines. Additionally the site includes a glossary of important terms, lesson plans, a teacher's guide and information about professionals who work with compound machines. This page is part of a larger collection of animated education resources for the elementary level.

2007-09-18

200

Perspex machine: VII. The universal perspex machine  

NASA Astrophysics Data System (ADS)

The perspex machine arose from the unification of projective geometry with the Turing machine. It uses a total arithmetic, called transreal arithmetic, that contains real arithmetic and allows division by zero. Transreal arithmetic is redefined here. The new arithmetic has both a positive and a negative infinity which lie at the extremes of the number line, and a number nullity that lies off the number line. We prove that nullity, 0/0, is a number. Hence a number may have one of four signs: negative, zero, positive, or nullity. It is, therefore, impossible to encode the sign of a number in one bit, as floating-point arithmetic attempts to do, resulting in the difficulty of having both positive and negative zeros and NaNs. Transrational arithmetic is consistent with Cantor arithmetic. In an extension to real arithmetic, the product of zero, an infinity, or nullity with its reciprocal is nullity, not unity. This avoids the usual contradictions that follow from allowing division by zero. Transreal arithmetic has a fixed algebraic structure and does not admit options as IEEE, floating-point arithmetic does. Most significantly, nullity has a simple semantics that is related to zero. Zero means "no value" and nullity means "no information." We argue that nullity is as useful to a manufactured computer as zero is to a human computer. The perspex machine is intended to offer one solution to the mind-body problem by showing how the computable aspects of mind and, perhaps, the whole of mind relates to the geometrical aspects of body and, perhaps, the whole of body. We review some of Turing's writings and show that he held the view that his machine has spatial properties. In particular, that it has the property of being a 7D lattice of compact spaces. Thus, we read Turing as believing that his machine relates computation to geometrical bodies. We simplify the perspex machine by substituting an augmented Euclidean geometry for projective geometry. This leads to a general-linear perspex-machine which is very much easier to program than the original perspex-machine. We then show how to map the whole of perspex space into a unit cube. This allows us to construct a fractal of perspex machines with the cardinality of a real-numbered line or space. This fractal is the universal perspex machine. It can solve, in unit time, the halting problem for itself and for all perspex machines instantiated in real-numbered space, including all Turing machines. We cite an experiment that has been proposed to test the physical reality of the perspex machine's model of time, but we make no claim that the physical universe works this way or that it has the cardinality of the perspex machine. We leave it that the perspex machine provides an upper bound on the computational properties of physical things, including manufactured computers and biological organisms, that have a cardinality no greater than the real-number line.

Anderson, James A. D. W.

2006-01-01

201

Machine Learning Group Machine Learning Group Machine Learning Group  

E-print Network

The deep Boltzmann machine is a powerful model that extracts the hierarchical structure of observed data. While inference is typically slow due to its undirected nature, we argue that the emerging feature hierarchy is still explicit enough to be traversed in a feedforward fashion. The claim is corroborated by training a set of deep neural networks on real data and measuring the evolution of the representation layer after layer. The analysis reveals that the deep Boltzmann machine produces a feed-forward hierarchy of increasingly invariant representations that clearly surpasses the layer-wise approach. 1

Grégoire Montavon; Mikio L. Braun; Klaus-robert Müller; Tu Berlin; Tu Berlin; Tu Berlin

202

The sawing machine is a machine SAWING MACHINES  

E-print Network

main parts, which are discussed below. The head is the large unit at the top of the contour machine), and the adjustable post which supports the upper saw guide. The job selector dial is also located on the head the speed in feet per minute (FPM). The butt welder is also mounted on the column. different positions

Gellman, Andrew J.

203

Machine tool locator  

DOEpatents

Machine tools can be accurately measured and positioned on manufacturing machines within very small tolerances by use of an autocollimator on a 3-axis mount on a manufacturing machine and positioned so as to focus on a reference tooling ball or a machine tool, a digital camera connected to the viewing end of the autocollimator, and a marker and measure generator for receiving digital images from the camera, then displaying or measuring distances between the projection reticle and the reference reticle on the monitoring screen, and relating the distances to the actual position of the autocollimator relative to the reference tooling ball. The images and measurements are used to set the position of the machine tool and to measure the size and shape of the machine tool tip, and examine cutting edge wear. patent

Hanlon, John A. (Los Alamos, NM); Gill, Timothy J. (Stanley, NM)

2001-01-01

204

Killer pop machines.  

PubMed

Abuse and misuse of soda vending machines has resulted in a considerable number of injuries and deaths. The machines fall forward when rocked or tilted and crush those in front. These accidents are all preventable by a simple and cheap device. There should be a law compelling safety requirements for these machines. This is a report of a recent case in which a young man was crushed to death. PMID:2329341

Spitz, D J; Spitz, W U

1990-03-01

205

Quantum Learning Machine  

E-print Network

We propose a novel notion of a quantum learning machine for automatically controlling quantum coherence and for developing quantum algorithms. A quantum learning machine can be trained to learn a certain task with no a priori knowledge on its algorithm. As an example, it is demonstrated that the quantum learning machine learns Deutsch's task and finds itself a quantum algorithm, that is different from but equivalent to the original one.

Jeongho Bang; James Lim; M. S. Kim; Jinhyoung Lee

2008-03-20

206

Parallel Kinematic Machines (PKM)  

SciTech Connect

The purpose of this 3-year cooperative research project was to develop a parallel kinematic machining (PKM) capability for complex parts that normally require expensive multiple setups on conventional orthogonal machine tools. This non-conventional, non-orthogonal machining approach is based on a 6-axis positioning system commonly referred to as a hexapod. Sandia National Laboratories/New Mexico (SNL/NM) was the lead site responsible for a multitude of projects that defined the machining parameters and detailed the metrology of the hexapod. The role of the Kansas City Plant (KCP) in this project was limited to evaluating the application of this unique technology to production applications.

Henry, R.S.

2000-03-17

207

Asymmetric universal entangling machine  

E-print Network

We give a definition of asymmetric universal entangling machine which entangles a system in an unknown state to a specially prepared ancilla. The machine produces a fixed state-independent amount of entanglement in exchange to a fixed degradation of the system state fidelity. We describe explicitly such a machine for any quantum system having $d$ levels and prove its optimality. We show that a $d^2$-dimensional ancilla is sufficient for reaching optimality. The introduced machine is a generalization to a number of widely investigated universal quantum devices such as the symmetric and asymmetric quantum cloners, the symmetric quantum entangler, the quantum information distributor and the universal-NOT gate.

Dmitri Horoshko; Mikhail Kolobov; Sergei Kilin

2004-12-23

208

What Can Turing Machines Do? How powerful are Turing machines?  

E-print Network

1 What Can Turing Machines Do? How powerful are Turing machines? Turing machines can accept any regular or context- free language. Turing machines can perform basic arithmetic computations. Sequencing can be implemented on Turing ma- chines. Subroutine calls can be implemented on Turing machines

Bylander, Tom

209

Circular tests for HSM machine tools: Bore machining application  

E-print Network

Circular tests for HSM machine tools: Bore machining application Abstract: Today's High was ultimately validated on a bore machining simulation. Keywords: circular interpolation, HSM, kinematic machine machining features can be extracted [3] [4] such as bores, holes, drillings, tapered holes and planes

Paris-Sud XI, Université de

210

Analysis of Machining Stability for a Parallel Machine Tool  

Microsoft Academic Search

Machine tool chatter is a self-excited vibration generated by chip thickness variation. It severely degrades the quality of the machined surface. The incidence of chatter is greatly affected by the dynamic characteristics of machine tool structure. This article extends chatter stability analysis to a machine tool equipped with a parallel mechanism. The vibration model of a parallel machine tool is

D. Hong; S. Kim; W. C. Choi; J.-B. Song

2003-01-01

211

Diamond machine tool face lapping machine  

DOEpatents

An apparatus for shaping, sharpening and polishing diamond-tipped single-point machine tools. The isolation of a rotating grinding wheel from its driving apparatus using an air bearing and causing the tool to be shaped, polished or sharpened to be moved across the surface of the grinding wheel so that it does not remain at one radius for more than a single rotation of the grinding wheel has been found to readily result in machine tools of a quality which can only be obtained by the most tedious and costly processing procedures, and previously unattainable by simple lapping techniques.

Yetter, H.H.

1985-05-06

212

Lecture outline Support vector machines  

E-print Network

Lecture outline · Support vector machines #12;Support Vector Machines · Find a linear hyperplane (decision boundary) that will separate the data #12;Support Vector Machines · One Possible Solution #12;Support Vector Machines · Another possible solution #12;Support Vector Machines · Other possible solutions

Terzi, Evimaria

213

Lecture outline Support vector machines  

E-print Network

Lecture outline · Support vector machines #12;Support Vector Machines · Find a linear hyperplane (decision boundary) that will separate the data #12;Support Vector Machines · One Possible Solution B1 #12;Support Vector Machines · Another possible solution B2 #12;Support Vector Machines · Other possible

Terzi, Evimaria

214

14. Interior, Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

14. Interior, Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific Railroad Carlin Shops, view to north (90mm lens). - Southern Pacific Railroad, Carlin Shops, Roundhouse Machine Shop Extension, Foot of Sixth Street, Carlin, Elko County, NV

215

Technique for Machining Glass  

NASA Technical Reports Server (NTRS)

Process for machining glass with conventional carbide tools requires a small quantity of a lubricant for aluminum applied to area of glass to be machined. A carbide tool is then placed against workpiece with light pressure. Tool is raised periodically to clear work of glass dust and particles. Additional lubricant is applied as it is displaced.

Rice, S. H.

1982-01-01

216

Imagining machines with imagination  

Microsoft Academic Search

The author reviews and comments upon George Morton's predictive paper “Machines with Imagination”. He argues that Morton's paper demonstrates a significant insight into the progress of machine intelligence, particularly because that progress was hardly accomplished in a linear progression of systematic advances. Indeed, the forecasts laid down in Morton's paper have become pertinent only after a series of relative failures

DAVID B. FOGEL

2000-01-01

217

Stirling machine operating experience  

SciTech Connect

Numerous Stirling machines have been built and operated, but the operating experience of these machines is not well known. It is important to examine this operating experience in detail, because it largely substantiates the claim that stirling machines are capable of reliable and lengthy operating lives. The amount of data that exists is impressive, considering that many of the machines that have been built are developmental machines intended to show proof of concept, and are not expected to operate for lengthy periods of time. Some Stirling machines (typically free-piston machines) achieve long life through non-contact bearings, while other Stirling machines (typically kinematic) have achieved long operating lives through regular seal and bearing replacements. In addition to engine and system testing, life testing of critical components is also considered. The record in this paper is not complete, due to the reluctance of some organizations to release operational data and because several organizations were not contacted. The authors intend to repeat this assessment in three years, hoping for even greater participation.

Ross, B. [Stirling Technology Co., Richland, WA (United States); Dudenhoefer, J.E. [Lewis Research Center, Cleveland, OH (United States)

1994-09-01

218

Simple Machines Made Simple.  

ERIC Educational Resources Information Center

Simple machines have become a lost point of study in elementary schools as teachers continue to have more material to cover. This manual provides hands-on, cooperative learning activities for grades three through eight concerning the six simple machines: wheel and axle, inclined plane, screw, pulley, wedge, and lever. Most activities can be…

St. Andre, Ralph E.

219

Cellular Multihead Turing Machine.  

National Technical Information Service (NTIS)

The Turing machine is a mathematical model for describing procedures. It can do any calculation that can be done by modern day computers. One disadvantage of the Turing machine is its very slow speed. One way to increase the speed is to increase the numbe...

L. Librizzi

1970-01-01

220

The Chemical Abstract Machine  

Microsoft Academic Search

We introduce a new kind of abstract machine based on the chemical metaphor used in the ? language of Banâtre & al. States of a machine are chemical solutions where floating molecules can interact according to reaction rules. Solutions can be stratified by encapsulating subsolutions within membranes that force reactions to occur locally. We illustrate the use of this model

Gérard Berry; Gérard Boudol

1990-01-01

221

From Reduction Machines To Narrowing Machines  

Microsoft Academic Search

Narrowing, the evaluation mechanism of functional logic languages, can be seen as a generalizationof reduction, the evaluation mechanism of purely functional languages. The unidirectionalpattern matching, which is used for parameter passing in functional languages, is simplyreplaced by the bidirectional unification known from logic programming languages. We showin this paper, how to extend a reduction machine, that has been designed for

Rita Loogen; RWTH Aachen

1991-01-01

222

On parallel machine scheduling 1  

E-print Network

On parallel machine scheduling 1 machines with setup times. The setup has to be performed by a single server. The objective is to minimize even for the case of two identical parallel machines. This paper presents a pseudopolynomial

Magdeburg, Universität

223

The Basic Anaesthesia Machine  

PubMed Central

After WTG Morton's first public demonstration in 1846 of use of ether as an anaesthetic agent, for many years anaesthesiologists did not require a machine to deliver anaesthesia to the patients. After the introduction of oxygen and nitrous oxide in the form of compressed gases in cylinders, there was a necessity for mounting these cylinders on a metal frame. This stimulated many people to attempt to construct the anaesthesia machine. HEG Boyle in the year 1917 modified the Gwathmey's machine and this became popular as Boyle anaesthesia machine. Though a lot of changes have been made for the original Boyle machine still the basic structure remains the same. All the subsequent changes which have been brought are mainly to improve the safety of the patients. Knowing the details of the basic machine will make the trainee to understand the additional improvements. It is also important for every practicing anaesthesiologist to have a thorough knowledge of the basic anaesthesia machine for safe conduct of anaesthesia. PMID:24249876

Gurudatt, CL

2013-01-01

224

DNA-Based Machines.  

PubMed

The base sequence in nucleic acids encodes substantial structural and functional information into the biopolymer. This encoded information provides the basis for the tailoring and assembly of DNA machines. A DNA machine is defined as a molecular device that exhibits the following fundamental features. (1) It performs a fuel-driven mechanical process that mimics macroscopic machines. (2) The mechanical process requires an energy input, "fuel." (3) The mechanical operation is accompanied by an energy consumption process that leads to "waste products." (4) The cyclic operation of the DNA devices, involves the use of "fuel" and "anti-fuel" ingredients. A variety of DNA-based machines are described, including the construction of "tweezers," "walkers," "robots," "cranes," "transporters," "springs," "gears," and interlocked cyclic DNA structures acting as reconfigurable catenanes, rotaxanes, and rotors. Different "fuels", such as nucleic acid strands, pH (H(+)/OH(-)), metal ions, and light, are used to trigger the mechanical functions of the DNA devices. The operation of the devices in solution and on surfaces is described, and a variety of optical, electrical, and photoelectrochemical methods to follow the operations of the DNA machines are presented. We further address the possible applications of DNA machines and the future perspectives of molecular DNA devices. These include the application of DNA machines as functional structures for the construction of logic gates and computing, for the programmed organization of metallic nanoparticle structures and the control of plasmonic properties, and for controlling chemical transformations by DNA machines. We further discuss the future applications of DNA machines for intracellular sensing, controlling intracellular metabolic pathways, and the use of the functional nanostructures for drug delivery and medical applications. PMID:24647836

Wang, Fuan; Willner, Bilha; Willner, Itamar

2014-01-01

225

Virtual Turing Machine 2  

NSDL National Science Digital Library

A Turing machine is theoretical computer consisting of a finite set of internal states, a finite alphabet that includes a blank symbol, and a finite set of instructions. It has a physical head and a physical infinitely long tape, which is divided into cells. The cell values consist of the alphabet. The tape has a finite number of non-blank cells. The head can read and write to the cells and move the tape one cell to the left and one cell to the right. The Virtual Turing Machine lets you input tape values and an instruction set to see the output of a turing machine.

Ming, Paul R.

226

Theory of Molecular Machines. I. Channel Capacity of Molecular Machines  

E-print Network

Theory of Molecular Machines. I. Channel Capacity of Molecular Machines running title: Channel Capacity of Molecular Machines Thomas D. Schneider version = 5.76 of ccmm.tex 2004 Feb 3 Version 5.67 was submitted 1990 December 5 Schneider, T. D. (1991). Theory of molecular machines. I. Channel capacity

Schneider, Thomas D.

227

Speech Recognition in Machines 785 Speech Recognition in Machines  

E-print Network

Speech Recognition in Machines 785 Speech Recognition in Machines Over the past several decades (speech recognition systems) human speech. We concentrate on speech recognition systems in this section. Speech recognition by machine refers to the capability of a machine to convert human speech to a textual

Liebling, Michael

228

16. Interior, Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

16. Interior, Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific Railroad Carlin Shops, view to south (90mm lens). Note the large segmental-arched doorway to move locomotives in and out of Machine Shop. - Southern Pacific Railroad, Carlin Shops, Roundhouse Machine Shop Extension, Foot of Sixth Street, Carlin, Elko County, NV

229

Universal Developer Platform for MachinePlatform for Machine  

E-print Network

1 Universal Developer Platform for MachinePlatform for Machine Control Applications Hansjoerg will need some things: · Senses · Means June 24-26, 2008 ETH Zurich #12;2 And for Machine Control? June 24 ETH Zurich Conclusion: big effort for things that have little to do with Machine Control Multi

230

Curious and Creative Machines  

Microsoft Academic Search

st -grade elementary school children. In the school's gymnasium hall, a few dozen 6-year-olds gathered enthusiastically around a few shiny machines with plenty of sensors and actuators, demonstrating patterns of locomotion. \\

Hod Lipson

2006-01-01

231

Design of Vitrification Machine  

E-print Network

and unreliable process. Moreover, there is a lack of standardization in the methods for preparing cells and biological material for the vitrification process. The purpose of the Vitrification Machine is to greatly simplify the process by making it faster, more...

McDonald, Todd William

2009-11-30

232

Protein Thin Film Machines  

E-print Network

We report the first example of microcantilever beams that are reversibly driven by protein thin film machines fuelled by cycling the salt concentration of the surrounding solution. We also show that upon the same salinity ...

Federici, Stefania

233

Machine For Grinding Fog  

E-print Network

Machine For Grinding Fog, an exhibition of stop motion animated films, revolves around three primary concerns: relationships, psychological or subjective reality, and relativity. Rooted within concerns of faith, personal ethics, and a re...

Ward, Nicholas Adam

2010-04-30

234

Positive Linear Function Machine  

NSDL National Science Digital Library

Students investigate linear functions with positive slopes by trying to guess the slope and intercept from inputs and outputs. Positive Linear Function Machine is one of the Interactivate assessment explorers.

235

Designing Sociable Machines  

Microsoft Academic Search

Sociable machines are a blend of art, science, and engineering. We highlight how insights from these disciplines have helped us to address a few key design issues for building expressive humanoid robots that interact with people in a social manner.

Cynthia Breazeal

236

Human-machine interactions  

SciTech Connect

Digital technology utilizing a cognitive model based on human naturalistic decision-making processes, including pattern recognition and episodic memory, can reduce the dependency of human-machine interactions on the abilities of a human user and can enable a machine to more closely emulate human-like responses. Such a cognitive model can enable digital technology to use cognitive capacities fundamental to human-like communication and cooperation to interact with humans.

Forsythe, J. Chris (Sandia Park, NM); Xavier, Patrick G. (Albuquerque, NM); Abbott, Robert G. (Albuquerque, NM); Brannon, Nathan G. (Albuquerque, NM); Bernard, Michael L. (Tijeras, NM); Speed, Ann E. (Albuquerque, NM)

2009-04-28

237

The Lisp Machine manual  

Microsoft Academic Search

This 471-page, softcover manual describes the programming language and software environment of the Lisp Machine developed at M.I.T.'s Artificial Intelligence Laboratory over the past 8 years. The Lisp Machine is the result of a successful experiment in computer science: a distributed computing system consisting of a network of powerful 32-bit personal computers, implemented with custom hardware and software as complete,

Daniel Weinreb; David Moon

1981-01-01

238

Working with simple machines  

NASA Astrophysics Data System (ADS)

A set of examples is provided that illustrate the use of work as applied to simple machines. The ramp, pulley, lever and hydraulic press are common experiences in the life of a student, and their theoretical analysis therefore makes the abstract concept of work more real. The mechanical advantage of each of these systems is also discussed so that students can evaluate their usefulness as machines.

Norbury, John W.

2006-11-01

239

Design a Flying Machine  

NSDL National Science Digital Library

The purpose of this activity is for the students to draw a design for their own flying machine. They will apply their knowledge of aircraft design and the forces acting on them. The students will start with a brainstorming activity where they come up with creative uses for every day objects. They will then use their creativity and knowledge of airplanes to design their own flying machine.

Integrated Teaching And Learning Program

240

Metalworking and machining fluids  

Microsoft Academic Search

Improved boron-based metal working and machining fluids. Boric acid and boron-based additives that, when mixed with certain carrier fluids, such as water, cellulose and\\/or cellulose derivatives, polyhydric alcohol, polyalkylene glycol, polyvinyl alcohol, starch, dextrin, in solid and\\/or solvated forms result in improved metalworking and machining of metallic work pieces. Fluids manufactured with boric acid or boron-based additives effectively reduce friction,

Ali Erdemir; Frank Sykora; Mark Dorbeck

2010-01-01

241

Weka Machine Learning Project  

NSDL National Science Digital Library

If you are inspired to try the process, the Weka Machine Learning Project from Waikato University offers open source software that can be used for data mining tasks. Visitors can also find the projects 1993 to 2006 publications, many of which are available for free in as PDFs. The "related" section offers a number of links to further information on topics such as artificial intelligence and machine learning.

2008-01-10

242

Metalworking and machining fluids  

DOEpatents

Improved boron-based metal working and machining fluids. Boric acid and boron-based additives that, when mixed with certain carrier fluids, such as water, cellulose and/or cellulose derivatives, polyhydric alcohol, polyalkylene glycol, polyvinyl alcohol, starch, dextrin, in solid and/or solvated forms result in improved metalworking and machining of metallic work pieces. Fluids manufactured with boric acid or boron-based additives effectively reduce friction, prevent galling and severe wear problems on cutting and forming tools.

Erdemir, Ali (Naperville, IL); Sykora, Frank (Caledon, ON, CA); Dorbeck, Mark (Brighton, MI)

2010-10-12

243

Driven Wave Machine Model  

NSDL National Science Digital Library

The Driven Wave Machine model simulates a wave machine driven by a sinusoidal oscillator. The machine consists of horizontal bars welded to a torsion rod that is perpendicular to the bars. The simulation allows the user to change the number of bars, the drive frequency, and the boundary conditions. The simulation also allows the user to change the lengths of the bars, thereby simulating the effect of a wave propagating in a non-uniform medium. The Driven Wave Machine model is a supplemental simulation for the article "Standing Waves in a Nonuniform Medium" by Paul Gluck in The Physics Teacher 49(2), 76-77 (2011) and has been approved by the authors and The Physics Teacher editor. The Driven Wave Machine model was created using the Easy Java Simulations (EJS) modeling tool. It is distributed as a ready-to-run (compiled) Java archive. Double clicking the ejs_mech_osc_chains_DrivenWaveMachine.jar file will run the program if Java is installed.

Christian, Wolfgang

2010-11-09

244

Wave Machine Model  

NSDL National Science Digital Library

This model simulates the wave generating machine created by John Shive at Bell Laboratories and made famous by the Similarities in Wave Behavior film. The machine consists of horizontal cross-bars welded to a central wire spine that is perpendicular to the bars. The spine was constructed so that it can freely twist, allowing the cross-bars to produce wave-like patterns. The simulation allows various pulse shapes to be sent down the machine by selecting a function for the twist of the first rod or by dragging the first rod. The far end of the wave machine can be free or fixed, which changes the nature of the reflected wave. Change the lengths of the bars to simulate the effect of a wave propagating in a non-uniform medium. The original film that introduced Dr. Shive's wave generating machine can be viewed at no cost: Film: Similarities of Wave Behavior (AT&T Archives and History Collection). The Wave Machine model was created using the Easy Java Simulations (EJS) modeling tool. It is distributed as a ready-to-run (compiled) Java archive.

Christian, Wolfgang

2014-06-13

245

The Knife Machine. Module 15.  

ERIC Educational Resources Information Center

This module on the knife machine, one in a series dealing with industrial sewing machines, their attachments, and operation, covers one topic: performing special operations on the knife machine (a single needle or multi-needle machine which sews and cuts at the same time). These components are provided: an introduction, directions, an objective,…

South Carolina State Dept. of Education, Columbia. Office of Vocational Education.

246

Applications of the Connection Machine  

Microsoft Academic Search

The Connection Machine development effort was initiated in the belief that parallel processing and artificial intelligence could together accelerate the rate of progress toward truly intelligent machines. This progress is the result of the ease with which the machine can be programmed and the dramatic increase in compute power that the machine can bring to bear. The authors have been

David L. Waltz

1987-01-01

247

Harvesting Machine Census 1999 & 2001  

E-print Network

1 Harvesting Machine Census 1999 & 2001 231 Corstorphine Road Edinburgh EH12 7AT www.forestry.gov.uk FCTN001 SUMMARY This Technical Note contains information on the 1999 and 2001 harvesting machine machines, converted forwarders, etc., account for the remaining machines. In the 2001 census, 65

248

MACHINE MONITORING USING PROBABILITY THRESHOLDS  

E-print Network

MACHINE MONITORING USING PROBABILITY THRESHOLDS AND SYSTEM OPERATING CHARACTERISTICS Stephen M a discrete-part production machine, with the objective of effectively determining when to shut the machine analysis: a) There is an underlying time interval that characterizes the operation of the machine, most

Pollock, Stephen

249

Machine Learning Thomas G. Dietterich  

E-print Network

Machine Learning Thomas G. Dietterich Department of Computer Science Oregon State University Corvallis, OR 97331 1 Introduction Machine Learning is the study of methods for programming computers a computer system. A machine learning system can study recorded data and subsequent machine failures

250

Stochastic Optimization for Machine Learning  

E-print Network

Stochastic Optimization for Machine Learning ICML 2010, Haifa, Israel Tutorial by Nati Srebro Descent: formulation, analysis and use in machine learning · Learn about extensions and generalizations, and their Machine Learning counterparts Main Goal: Machine Learning is Stochastic Optimization #12;Outline

Powell, Warren B.

251

Interactive Machine Learning Mustafa Bilgic  

E-print Network

Interactive Machine Learning Mustafa Bilgic "Who We Are" Seminars IIT 9/24/2013 #12;Bio Bachelor Komurlu 2 #12;Research Interests Machine learning Interactive machine learning Statistical relational Diagnosis Recommender Systems Search Engines 4 #12;How Does a Machine Learn? There are many approaches

Heller, Barbara

252

Non-traditional machining techniques  

SciTech Connect

During the course of machining targets for various experiments it sometimes becomes necessary to adapt fixtures or machines, which are designed for one function, to another function. When adapting a machine or fixture is not adequate, it may be necessary to acquire a machine specifically designed to produce the component required. In addition to the above scenarios, the features of a component may dictate that multi-step machining processes are necessary to produce the component. This paper discusses the machining of four components where adaptation, specialized machine design, or multi-step processes were necessary to produce the components.

Day, Robert D [Los Alamos National Laboratory; Fierro, Frank [Los Alamos National Laboratory; Garcia, Felix P [Los Alamos National Laboratory; Hatch, Douglass J [Los Alamos National Laboratory; Randolph, Randall B [Los Alamos National Laboratory; Reardon, Patrick T [Los Alamos National Laboratory; Rivera, Gerald [Los Alamos National Laboratory

2008-01-01

253

Enhanced virtual machining for sculptured surfaces by integrating machine tool error models into NC machining simulation  

Microsoft Academic Search

Sculptured surface machining is a time-consuming and costly process. It requires simultaneously controlled motion of the machine axes. However, positioning inaccuracies or errors exist in machine tools. The combination of error motions of the machine axes will result in a complicated pattern of part geometry errors. In order to quantitatively predict these part geometry errors, a new application framework ‘enhanced

Yizhen Lin; Yin-Lin Shen

2004-01-01

254

Circular tests for HSM machine tools: Bore machining application  

E-print Network

Today's High-Speed Machining (HSM) machine tool combines productivity and part quality. The difficulty inherent in HSM operations lies in understanding the impact of machine tool behaviour on machining time and part quality. Analysis of some of the relevant ISO standards (230-1998, 10791-1998) and a complementary protocol for better understanding HSM technology are presented in the first part of this paper. These ISO standards are devoted to the procedures implemented in order to study the behavior of machine tool. As these procedures do not integrate HSM technology, the need for HSM machine tool tests becomes critical to improving the trade-off between machining time and part quality. A new protocol for analysing the HSM technology impact during circular interpolation is presented in the second part of the paper. This protocol which allows evaluating kinematic machine tool behaviour during circular interpolation was designed from tests without machining. These tests are discussed and their results analysed i...

Tapie, Laurent; Anselmetti, Bernard

2009-01-01

255

The Bearingless Electrical Machine  

NASA Technical Reports Server (NTRS)

Electromagnetic bearings allow the suspension of solids. For rotary applications, the most important physical effect is the force of a magnetic circuit to a high permeable armature, called the MAXWELL force. Contrary to the commonly used MAXWELL bearings, the bearingless electrical machine will take advantage of the reaction force of a conductor carrying a current in a magnetic field. This kind of force, called Lorentz force, generates the torque in direct current, asynchronous and synchronous machines. The magnetic field, which already exists in electrical machines and helps to build up the torque, can also be used for the suspension of the rotor. Besides the normal winding of the stator, a special winding was added, which generates forces for levitation. So a radial bearing, which is integrated directly in the active part of the machine, and the motor use the laminated core simultaneously. The winding was constructed for the levitating forces in a special way so that commercially available standard ac inverters for drives can be used. Besides wholly magnetic suspended machines, there is a wide range of applications for normal drives with ball bearings. Resonances of the rotor, especially critical speeds, can be damped actively.

Bichsel, J.

1992-01-01

256

Swinging Atwood's Machine Model  

NSDL National Science Digital Library

The Swinging Atwood's Machine Model is an extension of the traditional Atwood's machine where one hanging mass is allowed to swing like a pendulum. One assumes that all motions for the swinging mass are possible including positions above the second peg which requires that the string remains rigid at all times. Unlike the traditional Atwood's machine, orbits or cycles are possible. In other words, for certain conditions, the motion of the Atwood's machine can continue indefinitely. In changing the ratio of the two masses and the initial angle of displacement, the trajectory of the swinging mass changes. The object of this simulation is to model that system and allow the user a large amount of control over initial conditions so that they may fully explore the system. The Swinging Atwood's Machine Model was created using the Easy Java Simulations (EJS) modeling tool. It is distributed as a ready-to-run (compiled) Java archive. Double clicking the ejs_comp_phys_swinging_atwoods.jar file will run the program if Java is installed.

Ruckle, Leah

2011-06-15

257

The Connection Machine  

SciTech Connect

This book describes what history may judge to be the second stage in the evolution of digital computers. Up to now, all computers have had basically the same architecture: one or a few large memory banks. Challenging that conception, the Connection Machine links together thousands or millions of extremely small processors and memories. From each moment to the next, the programs for this singularly versatile machine can refigure its architecture to suit the natural requirements of problems to be solved. The resulting configurations have already been applied to diverse data-structures required for processes involved with artificial intelligence, cellular physics, database inference, and number crunching computation.

Hillis, W.D.

1985-01-01

258

Precision Robotic Assembly Machine  

ScienceCinema

The world's largest laser system is the National Ignition Facility (NIF), located at Lawrence Livermore National Laboratory. NIF's 192 laser beams are amplified to extremely high energy, and then focused onto a tiny target about the size of a BB, containing frozen hydrogen gas. The target must be perfectly machined to incredibly demanding specifications. The Laboratory's scientists and engineers have developed a device called the "Precision Robotic Assembly Machine" for this purpose. Its unique design won a prestigious R&D-100 award from R&D Magazine.

None

2010-09-01

259

Paradigms for machine learning  

NASA Technical Reports Server (NTRS)

Five paradigms are described for machine learning: connectionist (neural network) methods, genetic algorithms and classifier systems, empirical methods for inducing rules and decision trees, analytic learning methods, and case-based approaches. Some dimensions are considered along with these paradigms vary in their approach to learning, and the basic methods are reviewed that are used within each framework, together with open research issues. It is argued that the similarities among the paradigms are more important than their differences, and that future work should attempt to bridge the existing boundaries. Finally, some recent developments in the field of machine learning are discussed, and their impact on both research and applications is examined.

Schlimmer, Jeffrey C.; Langley, Pat

1991-01-01

260

Automated fiber pigtailing machine  

DOEpatents

The Automated Fiber Pigtailing Machine (AFPM) aligns and attaches optical fibers to optoelectonic (OE) devices such as laser diodes, photodiodes, and waveguide devices without operator intervention. The so-called pigtailing process is completed with sub-micron accuracies in less than 3 minutes. The AFPM operates unattended for one hour, is modular in design and is compatible with a mass production manufacturing environment. This machine can be used to build components which are used in military aircraft navigation systems, computer systems, communications systems and in the construction of diagnostics and experimental systems.

Strand, Oliver T. (Castro Valley, CA); Lowry, Mark E. (Castro Valley, CA)

1999-01-01

261

Automated fiber pigtailing machine  

DOEpatents

The Automated Fiber Pigtailing Machine (AFPM) aligns and attaches optical fibers to optoelectronic (OE) devices such as laser diodes, photodiodes, and waveguide devices without operator intervention. The so-called pigtailing process is completed with sub-micron accuracies in less than 3 minutes. The AFPM operates unattended for one hour, is modular in design and is compatible with a mass production manufacturing environment. This machine can be used to build components which are used in military aircraft navigation systems, computer systems, communications systems and in the construction of diagnostics and experimental systems. 26 figs.

Strand, O.T.; Lowry, M.E.

1999-01-05

262

Precision Robotic Assembly Machine  

SciTech Connect

The world's largest laser system is the National Ignition Facility (NIF), located at Lawrence Livermore National Laboratory. NIF's 192 laser beams are amplified to extremely high energy, and then focused onto a tiny target about the size of a BB, containing frozen hydrogen gas. The target must be perfectly machined to incredibly demanding specifications. The Laboratory's scientists and engineers have developed a device called the "Precision Robotic Assembly Machine" for this purpose. Its unique design won a prestigious R&D-100 award from R&D Magazine.

2009-08-14

263

BRASS FOUNDRY MACHINE ROOM USED TO MACHINE CAST BRONZE PIECES ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

BRASS FOUNDRY MACHINE ROOM USED TO MACHINE CAST BRONZE PIECES FOR VALVES AND PREPARE BRONZE VALVE BODIES FOR ASSEMBLY. - Stockham Pipe & Fittings Company, Brass Foundry, 4000 Tenth Avenue North, Birmingham, Jefferson County, AL

264

42. MACHINE SHOP Machine shop area with small parts bins ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

42. MACHINE SHOP Machine shop area with small parts bins on the right and pipe storage racks on the left. Remains of the power drive system are suspended from the ceiling. - Hovden Cannery, 886 Cannery Row, Monterey, Monterey County, CA

265

Circular tests for HSM machine tools: Bore machining application  

Microsoft Academic Search

Today's High-Speed Machining (HSM) machine tool combines productivity and part quality. The difficulty inherent in HSM operations lies in understanding the impact of machine tool behaviour on machining time and part quality. Analysis of some of the relevant ISO standards (230-1998, 10791-1998) and a complementary protocol for better understanding HSM technology are presented in the first part of this paper.

Laurent Tapie; Kwamiwi Mawussi; Bernard Anselmetti

2009-01-01

266

Laser machining of explosives  

DOEpatents

The invention consists of a method for machining (cutting, drilling, sculpting) of explosives (e.g., TNT, TATB, PETN, RDX, etc.). By using pulses of a duration in the range of 5 femtoseconds to 50 picoseconds, extremely precise and rapid machining can be achieved with essentially no heat or shock affected zone. In this method, material is removed by a nonthermal mechanism. A combination of multiphoton and collisional ionization creates a critical density plasma in a time scale much shorter than electron kinetic energy is transferred to the lattice. The resulting plasma is far from thermal equilibrium. The material is in essence converted from its initial solid-state directly into a fully ionized plasma on a time scale too short for thermal equilibrium to be established with the lattice. As a result, there is negligible heat conduction beyond the region removed resulting in negligible thermal stress or shock to the material beyond a few microns from the laser machined surface. Hydrodynamic expansion of the plasma eliminates the need for any ancillary techniques to remove material and produces extremely high quality machined surfaces. There is no detonation or deflagration of the explosive in the process and the material which is removed is rendered inert.

Perry, Michael D. (Livermore, CA); Stuart, Brent C. (Fremont, CA); Banks, Paul S. (Livermore, CA); Myers, Booth R. (Livermore, CA); Sefcik, Joseph A. (Tracy, CA)

2000-01-01

267

The Art Machine.  

ERIC Educational Resources Information Center

Introduces educators to possibilities of computer graphics using an inexpensive computer system which takes advantage of existing equipment (35mm camera, super 8 movie camera, VHS video cassette recorder). The concept of the "art machine" is explained, highlighting input and output devices (X-Y plotter, graphic tablets, video digitizers). (EJS)

Vertelney, Harry; Grossberger, Lucia

1983-01-01

268

Deep Boltzmann Machines  

Microsoft Academic Search

We present a new learning algorithm for Boltz- mann machines that contain many layers of hid- den variables. Data-dependent expectations are estimated using a variational approximation that tends to focus on a single mode, and data- independent expectations are approximated us- ing persistent Markov chains. The use of two quite different techniques for estimating the two types of expectation that

Ruslan Salakhutdinov; Geoffrey E. Hinton

2009-01-01

269

Operating the Lisp Machine  

E-print Network

This document is a draft copy of a portion of the Lisp Machine window system manual. It is being published in this form now to make it available, since the complete window system manual is unlikely to be finished in the ...

Moon, David A.

270

Optimizing Embedded Virtual Machines  

Microsoft Academic Search

Virtual machines (VMs) play an important role in mainstream computing by enabling interoperability, security, and higher levels of abstraction. Their use in embedded computing systems is deterred primarily by the resource constraints of embedded microcontrollers. In this paper, we show how various optimizations can significantly decrease these overheads, making VMs viable as system software for even low-end (8- or 16-bit)

Joel Koshy; Raju Pandey; Ingwar Wirjawan

2009-01-01

271

Machine learning Julia Lasserre  

E-print Network

If a machine acts as intelligently as a human being, then it is as intelligent as a human being ­ includes in the late 80s too ambitious, resources not ready, etc... => end of AI as we dreamed it ­ the learning part codes) ­ cheques (amount) ­ websites recommendations (Google, Amazon, etc) #12;What is ML really? Arthur

Spang, Rainer

272

Lakatos and Machine Creativity  

Microsoft Academic Search

We argue that Lakatos' work on the history and philos- ophy of mathematics is of key relevance to machine creativity as it suggests ways in which to explore and transform concept spaces, re- represent knowledge and change evaluation criteria. We describe ap- proaches to implementing methods which Lakatos identifies, includ- ing our own approach, which extends Colton' s HR and

Alison Pease; Simon Colton; Alan Smaill; John Lee

2002-01-01

273

The Connection Machine  

Microsoft Academic Search

This book describes what history may judge to be the second stage in the evolution of digital computers. Up to now, all computers have had basically the same architecture: one or a few large memory banks. Challenging that conception, the Connection Machine links together thousands or millions of extremely small processors and memories. From each moment to the next, the

W. Daniel Hillis

1985-01-01

274

Automatic field machine technology  

Microsoft Academic Search

Current crop production schemes fail to offer the economic potential for reduced costs, increased yields and improved product quality, that could be derived from controlled traffic farming techniques utilizing multipurpose overhead mechanical frames. The development of new field machine technology will integrate total production under a single linear-travel system. This new technology is vital to reduce soil compaction with significantly

G. Manor

1995-01-01

275

Machine tools get smarter  

Microsoft Academic Search

This article describes how, using software, sensors, and controllers, a new generation of intelligent machine tools are optimizing grinding, milling, and molding processes. A paradox of manufacturing parts is that the faster the parts are made, the less accurate they are--and vice versa. However, a combination of software, sensors, controllers, and mechanical innovations are being used to create a new

Valenti

1995-01-01

276

8. VIEW OF THE MACHINE SHOP. BY 1966, THE MACHINE ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. VIEW OF THE MACHINE SHOP. BY 1966, THE MACHINE SHOP HANDLED PRIMARILY STAINLESS STEEL COMPONENTS, WHICH WERE SENT TO THE MACHINE SHOP TO BE FORMED INTO THEIR FINAL SHAPES. (7/24/70) - Rocky Flats Plant, General Manufacturing, Support, Records-Central Computing, Southern portion of Plant, Golden, Jefferson County, CO

277

Compiling for NUMA Parallel Machines  

E-print Network

Compiling for NUMA Parallel Machines Abstract A common feature of many scalable parallel machines is non-uniform memory access (NUMA). A parallelizing compiler for NUMA parallel ma- chines must exploit both parallelism and data locality

Zanibbi, Richard

278

Automatically-Programed Machine Tools  

NASA Technical Reports Server (NTRS)

Software produces cutter location files for numerically-controlled machine tools. APT, acronym for Automatically Programed Tools, is among most widely used software systems for computerized machine tools. APT developed for explicit purpose of providing effective software system for programing NC machine tools. APT system includes specification of APT programing language and language processor, which executes APT statements and generates NC machine-tool motions specified by APT statements.

Purves, L.; Clerman, N.

1985-01-01

279

Move it! With Simple Machines  

NSDL National Science Digital Library

In this Science NetLinks lesson, students will start by discussing a couple of the simple machines and what the purpose of them might be. Then, after reading a short page on each simple machine, they will discuss how the simple machines function. They will explore this briefly in a hands-on fashion and lead into the discussion and realization that these tools are the base for almost any machine or more complex tool that we use.

Science Netlinks;

2003-01-21

280

Soda pop vending machine injuries.  

PubMed

Fifteen male patients, 15 to 24 years of age, sustained injuries after rocking soda machines. The machines fell onto the victims, resulting in a variety of injuries. Three were killed. The remaining 12 required hospitalization for their injuries. Unless changes are made to safeguard these machines, people will continue to suffer severe and possibly fatal injuries from what are largely preventable accidents. PMID:3184337

Cosio, M Q

1988-11-11

281

Lightning Protection for Rotating Machines  

Microsoft Academic Search

The high monetary value and low insulation levels of rotating machines make it necessary to employ special protection. A rotating machine can be conceived as a transmission line with distributed constants, the essential difference being that the machine winding is wound back on itself in the form of turns, which may permit high voltage across the turn-to-turn insulation. The installation

G. D. McCann; E. Beck; L. A. Finzi

1944-01-01

282

Hydraulic Fatigue-Testing Machine  

NASA Technical Reports Server (NTRS)

Fatigue-testing machine applies fluctuating tension to number of specimens at same time. When sample breaks, machine continues to test remaining specimens. Series of tensile tests needed to determine fatigue properties of materials performed more rapidly than in conventional fatigue-testing machine.

Hodo, James D.; Moore, Dennis R.; Morris, Thomas F.; Tiller, Newton G.

1987-01-01

283

The Fusion Machine (extended abstract)  

E-print Network

The Fusion Machine (extended abstract) Philippa Gardner Cosimo Laneve Lucian Wischik March 27, 2002. In particular, we describe a dis- tributed abstract machine called the fusion machine. In it, only channels exist at runtime. It uses a form of concurrent constraints called fusions--equations on channel names

Gardner, Philippa

284

Toward Machines with Emotional Intelligence  

E-print Network

and how to display emotion in ways that enable the machine to appear empathetic or otherwise emotionally1 Toward Machines with Emotional Intelligence Rosalind W. Picard MIT Media Laboratory Abstract pets, desktop computers, and more) skills of emotional intelligence. Machines have long been able

285

The Cooling of Electric Machines  

Microsoft Academic Search

The elevation in temperature of the windings of any electric machine due to the internal heat losses is usually the dominating factor in limiting the rating of the machine. This limitation found in the heating, is primarily due to the effects of high temperatures on the various types of insulation used in such machines. The American Institute of Electrical Engineers

George E. Luke

1923-01-01

286

Toolbox Safety Talk Woodworking Machines  

E-print Network

Toolbox Safety Talk Woodworking Machines Environmental Health & Safety Facilities Safety & Health to Environmental Health & Safety for recordkeeping. Machine shops are an integral part of the Cornell University for many student courses and elective activities. Woodworking machines can pose a myriad of hazards

Pawlowski, Wojtek

287

Student Modeling and Machine Learning  

Microsoft Academic Search

After identifying essential student modeling issues and machine learning approaches, this paper examines how machine learning techniques have been used to automate the construction of student models as well as the background knowledge necessary for student modeling. In the process, the paper sheds light on the difficulty, suitability and potential of using machine learning for student modeling processes, and, to

Raymund Sison; Masamichi Shimura

288

High-performance reading machines  

Microsoft Academic Search

The architecture of a reading machine designed to achieve a high rate of correct interpretation of text as well as high speed in performing the interpretation is described. The refinement of the architecture for a specialized reading machine, to find and interpret addresses on a stream of postal letters, is also described. The addresses can be either machine-printed or handwritten.

SARGUR N. SRIHARI

1992-01-01

289

Linear-motion electrical machines  

Microsoft Academic Search

A survey of linear-motion electrical machines is presented. Although various types of dc and ac linear machines are briefly mentioned, linear induction motors are the main concern of the paper and they are discussed in considerable detail. Based on topological considerations, a classification of these machines is presented and their development through the last 70 years is reviewed. A brief

E. R. Laithwaite; S. A. Nasar

1970-01-01

290

Numerical Control of Machine Tools  

Microsoft Academic Search

Industry needs more flexible methods of programming machine cycles to achieve automatic operation of machine tools in limited-quantity production. Part of this need is met by numerical control systems which command the machine in accordance with prepared numerical instructions read from a storage medium. Such numerical instruction can be stored in binary or decimal numerical form on punched telegraph tape,

Leroy U. C. Kelling

1955-01-01

291

Machine Learning Thomas G. Dietterich  

E-print Network

Machine Learning Thomas G. Dietterich Department of Computer Science Oregon State University Corvallis, OR 97331 1 Introduction Machine Learning is the study of methods for programming computers necessary to build a computer system. A machine learning system can study recorded data and subsequent

Bylander, Tom

292

Photovoltaic Thai Silk Spinning Machine  

Microsoft Academic Search

This research presents the design and development of a photovoltaic Thai silk spinning machine for silk clothes product for One Tambol One Product (OTOP) in Thailand. This machine is based on PIC microcontroller for control speed of motor and battery charger. The results of this research, the machine helps Thai villagers for silk spinning by hand and makes little products

Denpong Sirikul; Narong Mungkung; Ratchadawan Nimnual

293

Sequence invariant state machines  

NASA Technical Reports Server (NTRS)

A synthesis method and new VLSI architecture are introduced to realize sequential circuits that have the ability to implement any state machine having N states and m inputs, regardless of the actual sequence specified in the flow table. A design method is proposed that utilizes BTS logic to implement regular and dense circuits. A given state sequence can be programmed with power supply connections or dynamically reallocated if stored in a register. Arbitrary flow table sequences can be modified or programmed to dynamically alter the function of the machine. This allows VLSI controllers to be designed with the programmability of a general purpose processor but with the compact size and performance of dedicated logic.

Whitaker, S.; Manjunath, S.

1990-01-01

294

Smart Machine Protection System  

SciTech Connect

A Machine Protection System implemented on the SLC automatically controls the beam repetition rates in the accelerator so that radiation or temperature faults slow the repetition rate to bring the fault within tolerance without shutting down the machine. This process allows the accelerator to aid in the fault diagnostic process, and the protection system automatically restores the beams back to normal rates when the fault is diagnosed and corrected. The user interface includes facilities to monitor the performance of the system, and track rate limits, faults, and recoveries. There is an edit facility to define the devices to be included in the protection system, along with their set points, limits, and trip points. This set point and limit data is downloaded into the CAMAC modules, and the configuration data is compiled into a logical decision tree for the 68030 processor. 3 figs.

Clark, S.; Nelson, D.; Grillo, A.; Spencer, N.; Hutchinson, D.; Olsen, J.; Millsom, D.; White, G.; Gromme, T.; Allison, S.; Underwood, K.; Zelazny, M.; Kang, H.

1991-11-01

295

Future of caring machines.  

PubMed

Feeling cared for has profound effects on physiology, cognition and emotional state, and has significant health ramifications whether the source of this feeling is an intimate other, friend or health provider. Unfortunately, not everyone has access to social networks populated with caring individuals or has health providers who are patient, empathic and reliably available when emotional support is needed. Over the last decade, a range of computational artifacts and technologies have been developed that could help fill this unmet need in many peoples' lives. Caring machines are technologies that interact with an individual to accomplish a goal while also behaving in ways that give the individual the feeling of being cared for. This chapter presents evidence that these machines can begin to lead to significant health benefits, such as increased adherence to prescribed health behavior change and medication regimens. PMID:16301775

Bickmore, Timothy; Picard, Rosalind W

2005-01-01

296

Special Article Elucidating Nature's Solutions to Heart, Lung, and Blood  

E-print Network

of new therapeutic approaches. Examples include species that tolerate acute or chronic hypoxemia like of animal species that have evolved extraordinary phenotypes as well as the expectations for new in biomedical research is to examine naturally occurring varia- tions in animal species that are adapted

Storz, Jay F.

297

Dynamic monocular machine vision  

Microsoft Academic Search

A new approach to real-time machine vision in dynamic scenes is presented based on special hardware and methods for feature extraction and information processing. Using integral spatio-temporal models, it by-passes the nonunique inversion of the perspective projection by applying recursive least squares filtering. By prediction error feedback methods similar to those used in modern control theory, all spatial state variables

Ernst Dieter Dickmanns; Volker Graefe

1988-01-01

298

The Variable Machine  

NSDL National Science Digital Library

This lesson from Illuminations provides an introduction to the use of variables, and develops students' algebraic thinking. Students create variable machines to discover the value of words by assigning each letter of the alphabet a unique number value. Learning objectives, a materials list, a pdf file of the student worksheet, an instructional plan, questions for the students, assessment options, extensions, and teacher reflections are provided.

2008-01-01

299

Machine Translation from Text  

NASA Astrophysics Data System (ADS)

Machine translation (MT) from text, the topic of this chapter, is perhaps the heart of the GALE project. Beyond being a well defined application that stands on its own, MT from text is the link between the automatic speech recognition component and the distillation component. The focus of MT in GALE is on translating from Arabic or Chinese to English. The three languages represent a wide range of linguistic diversity and make the GALE MT task rather challenging and exciting.

Habash, Nizar; Olive, Joseph; Christianson, Caitlin; McCary, John

300

Optimal Quantum Cloning Machines  

E-print Network

We present Quantum Cloning Machines (QCM) that transform N identical qubits into $M>N$ identical copies and we prove that the fidelity (quality) of these copies is optimal. The connection between cloning and measurement is discussed in detail. When the number of clones M tends towards infinity, the fidelity of each clone tends towards the optimal fidelity that can be obtained by a measurement on the input qubits. More generally, the QCM are universal devices to translate quantum information into classical information.

N. Gisin; S. Massar

1997-05-27

301

Instruments and Machines  

Microsoft Academic Search

\\u000a Galileo’s apprenticeship allowed him to build bridges to mathematicians, philosophers and several kinds of artist-engineers\\u000a and craftsmen, including mirror makers, military engineers, and machine builders. In the context of such a network, Galileo\\u000a cultivated and practiced all of these activities himself. He opened his own workshop in Padova, which produced mathematical\\u000a instruments for military officers; starting in 1610, upon his

Matteo Valleriani

302

Reading What Machines \\  

Microsoft Academic Search

In this paper, we want to farther advance the parallelism between models of the brain and computing machines. We want to apply\\u000a the same idea underlying neuroimaging techniques to electronic computers. Applying this parallelism, we can address these\\u000a two questions: (1) how far we can go with neuroimaging in understanding human mind? (foundational perspective); (2) can we understand what computers

Fabio Massimo Zanzotto; Danilo Croce

2009-01-01

303

Tunnel boring machine  

SciTech Connect

A tunneling machine is disclosed which includes a hollow shield, a nonrotatable outer housing mounted in the shield for longitudinal movement, and inner housing rotatably mounted within the outer housing, an excavator including a boom and bucket pivotally mounted on the forward end of the inner housing, and a boom cylinder having a forward portion pivotally engaged with the boom and a rear portion mounted at the rearward portion of the inner housing.

Dillingham, R.G.; Hamburger, H.

1982-09-14

304

PC\\/370 virtual machine  

Microsoft Academic Search

PC\\/370 Virtual Machine is a software package containing an IBM 370 cross assembler, linkage editor, and 370 emulator for use by students and programmers on any MS-DOS compatible PC such as the IBM PC, XT, or AT with 128K of memory. The software was originally developed in 1981 for CP\\/M-80 Z80 systems with 64K. (1) The cross assembler translates standard

Donald S. Higgins

1985-01-01

305

Meso-Machining Capabilities  

Microsoft Academic Search

Meso-scale manufacturing processes are bridging the gap between silicon-based MEMS processes and conventional miniature machining. These processes can fabricate two and three-dimensional parts having micron size features in traditional materials such as stainless steels, rare earth magnets, ceramics, and glass. Meso-scale processes that are currently available include, focused ion beam sputtering, micro-milling, micro-turning, excimer laser ablation, femtosecond laser ablation, and

GILBERT L. BENAVIDES; DAVID P. ADAMS; PIN YANG

2001-01-01

306

Boltzmann Machine Model  

NSDL National Science Digital Library

The Boltzmann Machine Model simulates a ping-pong ball moving around on two flat surfaces that are connected by a ramp. This ball is given occasional random "kicks" which cause the ball to move unpredictably. Remarkably, this simple system is a macroscopic example of a two-level system* that obeys the Boltzmann distribution function. The Boltzmann distribution is typically associated with a microscopic system in contact with a heat bath; but in this case, the system is macroscopic and easy to visualize, and the random kicks serve the role of the heat bath. In Ref. 1, "Squiggle Balls" were used to produce the kicks for the Boltzmann Machine experiment, whereas in this simulation we use randomly generated velocities to produce the kicks. The advantage to using this simulation (as opposed to the experiment) is that parameters can be manipulated, and results can be obtained, much more quickly and easily. The Boltzmann Machine Model was developed using the Easy Java/JavaScript Simulations (EjsS) modeling tool version 5. It is distributed as a ready-to-run (compiled) Java archive. Double clicking the ejs_fmu_BoltzmannMachine.jar file will run the program if Java is installed. You can modify this simulation if you have EJS installed by right-clicking within the map and selecting "Open Ejs Model" from the pop-up menu item. *This is a âtwo-levelâ system in the sense that there are two different values of potential energy: the value on the top surface and the value on the bottom surface. 1. J. J. Prentis, American Journal of Physics 68, 1073 (2000). This work was supported in part by NSF-TUES grant DUE-1140034.

Engelhardt, Larry; Puerto, Marie L.

2014-08-02

307

Study on a new kind of combined machining technology of ultrasonic machining and electrical discharge machining  

Microsoft Academic Search

An analysis on the mechanisms of ultrasonic machining and electrical discharge machining has been carried out, and a technology, which combines the advantages of both of them, has been proposed in this paper. It can be used to machine all conductive hard and brittle materials with high efficiency and surface integrity. The mechanism of this combined technology has been studied

Jia Zhixin; Zhang Jianhua; Ai Xing

1997-01-01

308

Computational Models -Lecture 6 Turing Machines  

E-print Network

Computational Models - Lecture 6 Turing Machines Slides modified by Benny Chor, based on original Models - Lecture 6 Turing Machines Turing Machines Slides modified by Benny Chor, based on original Models - Lecture 6 Turing Machines Turing Machines Turing Machines Slides modified by Benny Chor, based

Beimel, Amos

309

15. Interior, Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

15. Interior, Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific Railroad Carlin Shops, view to northeast (90mm lens). The arched cutouts in the bottom chords of the roof trusses were necessary to provide clearance for the smokestacks of steam locomotives, and also mark the location of the former inspection pit in the floor (now filled in and covered by a new concrete floor). - Southern Pacific Railroad, Carlin Shops, Roundhouse Machine Shop Extension, Foot of Sixth Street, Carlin, Elko County, NV

310

Linear Function Machine  

NSDL National Science Digital Library

In this activity, students plug values into a function to see what the output is for that function. Then based on that information, they have to guess the coefficient and constant for a linear function. This activity allows students to explore linear functions and what input values are useful to figuring out the linear function performed by the function machine. This activity includes supplemental materials, including background information about the topics covered, a description of how to use the application, and exploration questions for use with the java applet.

2010-01-01

311

Will machines ever think  

NASA Technical Reports Server (NTRS)

Artificial Intelligence research has come under fire for failing to fulfill its promises. A growing number of AI researchers are reexamining the bases of AI research and are challenging the assumption that intelligent behavior can be fully explained as manipulation of symbols by algorithms. Three recent books -- Mind over Machine (H. Dreyfus and S. Dreyfus), Understanding Computers and Cognition (T. Winograd and F. Flores), and Brains, Behavior, and Robots (J. Albus) -- explore alternatives and open the door to new architectures that may be able to learn skills.

Denning, P. J.

1986-01-01

312

The Partial Derivative Machine  

NSDL National Science Digital Library

Research has shown that students struggle to understand the use of partial derivatives in thermodynamics. We have designed an apparatus, which we have called a Partial Derivative Machine, that serves as a mechanical analogue of a thermodynamic system. Using this device, students have a tangible way to wrestle with issues related to partial derivatives and thermodynamics, such as which variables are held fixed, how many variables are independent, and how energy can be added to a system. In this paper, we present a description of the apparatus, an introduction to the associated activities, and an overview of how this apparatus can be connected to thermodynamic systems.

Sherer, Grant; Kustusch, Mary B.; Manogue, Corinne A.; Roundy, David J.

2014-01-31

313

Quantum adiabatic machine learning  

E-print Network

We develop an approach to machine learning and anomaly detection via quantum adiabatic evolution. In the training phase we identify an optimal set of weak classifiers, to form a single strong classifier. In the testing phase we adiabatically evolve one or more strong classifiers on a superposition of inputs in order to find certain anomalous elements in the classification space. Both the training and testing phases are executed via quantum adiabatic evolution. We apply and illustrate this approach in detail to the problem of software verification and validation.

Kristen L. Pudenz; Daniel A. Lidar

2011-09-01

314

Extremal asymmetric universal cloning machines  

E-print Network

The trade-offs among various output fidelities of asymmetric universal cloning machines are investigated. First we find out all the attainable optimal output fidelities for the 1 to 3 asymmetric universal cloning machine and it turns out that there are two kinds of extremal asymmetric cloning machines which have to cooperate in order to achieve some of the optimal output fidelities. Second we construct a family of extremal cloning machines that includes the universal symmetric cloning machine as well as an asymmetric 1 to $1+N$ cloning machine for qudits with two different output fidelities such that the optimal trade-off between the measurement disturbance and state estimation is attained in the limit of infinite $N$.

Mingming Jiang; Sixia Yu

2012-02-08

315

Extremal asymmetric universal cloning machines  

E-print Network

The trade-offs among various output fidelities of asymmetric universal cloning machines are investigated. First we find out all the attainable optimal output fidelities for the 1 to 3 asymmetric universal cloning machine and it turns out that there are two kinds of extremal asymmetric cloning machines which have to cooperate in order to achieve some of the optimal output fidelities. Second we construct a family of extremal cloning machines that includes the universal symmetric cloning machine as well as an asymmetric 1 to $1+N$ cloning machine for qudits with two different output fidelities such that the optimal trade-off between the measurement disturbance and state estimation is attained in the limit of infinite $N$.

Jiang, Mingming

2012-01-01

316

Multiple man-machine interfaces  

NASA Technical Reports Server (NTRS)

The multiple man machine interfaces inherent in military pilot training, their social implications, and the issue of possible negative feedback were explored. Modern technology has produced machines which can see, hear, and touch with greater accuracy and precision than human beings. Consequently, the military pilot is more a systems manager, often doing battle against a target he never sees. It is concluded that unquantifiable human activity requires motivation that is not intrinsic in a machine.

Stanton, L.; Cook, C. W.

1981-01-01

317

Smart Test Machines  

NASA Technical Reports Server (NTRS)

Vern Wedeven, president of Wedeven Associates, developed the WAM4, a computer-aided "smart" test machine for simulating stress on equipment, based on his bearing lubrication expertise gained while working for Lewis Research Center. During his NASA years from the 1970s into the early 1980s, Wedeven initiated an "Interdisciplinary Collaboration in Tribology," an effort that involved NASA, six universities, and several university professors. The NASA-sponsored work provided foundation for Wedeven in 1983 to form his own company. Several versions of the smart test machine, the WAM1, WAM2, and WAM3, have proceeded the current version, WAM4. This computer-controlled device can provide detailed glimpses at gear and bearing points of contact. WAM4 can yield a three-dimensional view of machinery as an operator adds "what-if" thermal and lubrication conditions, contact stress, and surface motion. Along with NASA, a number of firms, including Pratt & Whitney, Caterpillar Tractor, Exxon, and Chevron have approached Wedeven for help on resolving lubrication problems.

1997-01-01

318

Interaction with Machine Improvisation  

NASA Astrophysics Data System (ADS)

We describe two multi-agent architectures for an improvisation oriented musician-machine interaction systems that learn in real time from human performers. The improvisation kernel is based on sequence modeling and statistical learning. We present two frameworks of interaction with this kernel. In the first, the stylistic interaction is guided by a human operator in front of an interactive computer environment. In the second framework, the stylistic interaction is delegated to machine intelligence and therefore, knowledge propagation and decision are taken care of by the computer alone. The first framework involves a hybrid architecture using two popular composition/performance environments, Max and OpenMusic, that are put to work and communicate together, each one handling the process at a different time/memory scale. The second framework shares the same representational schemes with the first but uses an Active Learning architecture based on collaborative, competitive and memory-based learning to handle stylistic interactions. Both systems are capable of processing real-time audio/video as well as MIDI. After discussing the general cognitive background of improvisation practices, the statistical modelling tools and the concurrent agent architecture are presented. Then, an Active Learning scheme is described and considered in terms of using different improvisation regimes for improvisation planning. Finally, we provide more details about the different system implementations and describe several performances with the system.

Assayag, Gerard; Bloch, George; Cont, Arshia; Dubnov, Shlomo

319

Large Surface Measuring Machine  

NASA Astrophysics Data System (ADS)

A new surface measuring concept developed under government contract at Itek Optical Systems has been previously reported by Allen Greenleaf. The method uses four steerable distance-measuring interferometers at the corners of a tetrahedron to determine the posi-tions of a retroreflecting target at various locations on the surface being measured. A small wooden breadboard had been built and tested, demonstrating the feasibility of the concept. This paper reports the building of a scaled-up prototype surface measuring machine to allow the measurement of large aspheric surfaces. A major advantage of the device is that, unlike conventional interferometry, it provides surface measurement in absolute coordinates, thus allowing direct determination of radius of curvature. In addition, the device is self-calibrating. Measurements of a 24-inch mirror have been made with the new machine, giving repeatability of 4 µ m peak sag in the curvature and accuracy of 0.7 ?m rms in the surface figure at best focus. The device is currently being used in the production grinding of large aspheric mirrors at Itek. The device is potentially scalable to other industries where highly accurate measurement of unusual surfaces is required.

Egdall, Mark; Breidenthal, Robert S.

1983-09-01

320

Internet Archive Wayback Machine  

NSDL National Science Digital Library

The Internet Archive is the "parent" site for two sites previously reviewed in the Scout Report, Election 2000 (see the July 13, 2001 Scout Report) and September11.archive.org (see the October 19, 2001 Scout Report). The Archive has been cataloging Webpages since its inception in 1996, and for their fifth anniversary has opened the archive to the public by launching their "Wayback Machine." To operate the "Machine," users type a URL into the search box, which will call up dated, archived pages of the site. The Internet Archive holds ten billion Webpages, making it the largest known database. Since announcing public access to the overall database, the site has experienced a great deal of traffic. They are in the process of adding servers, but users should be warned that, in the meantime, access may be tricky. The Internet Archive is a nonprofit, which has received funding from a number of sources including the Library of Congress and the National Science Foundation.

2001-01-01

321

Zeeman Catastrophe Machine Model  

NSDL National Science Digital Library

The Zeeman Catastrophe Machine Model shows the rotational motion of wheel that is free to rotate but is connected to two elastics, one which is free to move in the xy-plane, and one that is set a fixed distance d away. The model initiates in a steady state where there is no rotational velocity and the magnitude of the tensions in the two elastics are equal. The user can drag the blue point to change the torque on the wheel, or they can enter values in the input fields on the top panel. The user can also change the angle theta, the coefficient of dampening, the spring constant, the moment of inertia. The Zeeman Catastrophe Machine Model was developed as a final project in a sophomore-level Computational Physics course (Phy 200) using the Easy Java Simulations (EJS) modeling tool. It is distributed as a ready-to-run (compiled) Java archive. Double clicking the jar file will run the program if Java is installed. You can modify this simulation if you have EJS installed by right-clicking within the map and selecting "Open Ejs Model" from the pop-up menu item.

Glasmann, Andreu

2012-06-26

322

PARALLEL DATABASE MACHINES Kjell Bratbergsengen  

E-print Network

PARALLEL DATABASE MACHINES Kjell Bratbergsengen Department of Computer Systems and Telematics in the Database Technology Group at The Department of Computer Systems and Telematics, NTH has been supported

323

Earth boring machine and method  

SciTech Connect

An earth boring machine and method are disclosed. An above-ground reference line, such as a laser beam, is established for a hole to be bored. The direction of the reference line is detected. The direction of a cutting head of the boring machine in a bore hole is detected and signals of the detected direction are transmitted to a control unit for comparison with the reference line direction. The boring machine is controlled with, for example, cam actuated adjustable peripheral cutters on the cutting head so that the direction of the boring machine can be adjusted to that of the reference line.

Sullinger, R.

1983-09-13

324

Robust Minimax Probability Machine Regression Robust Minimax Probability Machine Regression  

E-print Network

show how to compute a direct estimate of this probability for any given margin > 0. Following the idea with a known mean and covariance matrix. In other words, we maximize the minimum probability of our regressionRobust Minimax Probability Machine Regression Robust Minimax Probability Machine Regression Thomas

Mulligan, Jane

325

Machine performance assessment and enhancement for a hexapod machine  

SciTech Connect

The focus of this study is to develop a sensor fused process modeling and control methodology to model, assess, and then enhance the performance of a hexapod machine for precision product realization. Deterministic modeling technique was used to derive models for machine performance assessment and enhancement. Sensor fusion methodology was adopted to identify the parameters of the derived models. Empirical models and computational algorithms were also derived and implemented to model, assess, and then enhance the machine performance. The developed sensor fusion algorithms can be implemented on a PC-based open architecture controller to receive information from various sensors, assess the status of the process, determine the proper action, and deliver the command to actuators for task execution. This will enhance a hexapod machine`s capability to produce workpieces within the imposed dimensional tolerances.

Mou, J.I. [Arizona State Univ., Tempe, AZ (United States); King, C. [Sandia National Labs., Livermore, CA (United States). Integrated Manufacturing Systems Center

1998-03-19

326

Shortwall mining machine  

SciTech Connect

The invention provides a shortwall mining machine comprising an assembly, which preferably is articulated and has a protective canopy. The assembly is arranged parallel to a shortwall mineral face, and a cutter is hauled along a guide on the assembly to cut the face. As the face is cut the assembly is moved towards the face by use of rams connected between the assembly and stay units located in roadways adjacent the face. The cutter may be a scraper bucket or a plough, and is hauled across the face by either one motor in one of the roadways, or by two motors, one located in each roadway. The cutter may be steered by use of jacks on the assembly located in the roadways.

MacRae, R.L.

1980-04-08

327

Crystal cleaving machine  

NASA Technical Reports Server (NTRS)

A machine is disclosed for cleaving hard crystals. A typical example of which is lithium fluoride, with prcision and uniformity and includes vertical axis positioning control means for an adjustable spring tension guided hammer mechanism employed to strike an anvil. A crystal cleaving shock wave transmitted to a cleaving blade is generated having an angulated cleaving edge in contact with one corner of the crystal. Connection between the anvil and the blade is by means of a pair of vertical shafts held in substantially friction free engagement by two pairs of adjustable linear bearings. An underlying crystal holding fixture with horizontal position control means includes a zero reference stop face for the crystal and opposing spring-loaded clamping and vertical positioning elements which are precisely guided.

Hallberg, F. C.; Benedicto, J. S. J. (inventors)

1982-01-01

328

Materials for advanced electric machines: an overview  

Microsoft Academic Search

Materials behavior, along with the machine design, controls the performance of the electric machine. Advanced electric machines are placing increased demands on materials behavior especially to achieve power density, efficiency, and endurance. For the electric ship, such advanced electric machines include actuators, motors, generators, certain energy storage systems, electric clutches and brakes, and specialized machines for weaponry. Small engineering refinements

A. T. Wilder

2005-01-01

329

Machine Learning ! ! ! ! ! Srihari Ising Models, Boltzmann  

E-print Network

Machine Learning ! ! ! ! ! Srihari 1 Ising Models, Boltzmann Machines, Deep Belief Networks Sargur Srihari srihari@cedar.buffalo.edu #12;Machine Learning ! ! ! ! ! Srihari Topics · Ising Model · Boltzmann Distribution · Energy Based Model · Boltzmann Machine · Restricted Boltzmann Machine · Deep Belief Networks

330

Machining of uranium and uranium alloys  

SciTech Connect

Uranium and uranium alloys can be readily machined by conventional methods in the standard machine shop when proper safety and operating techniques are used. Material properties that affect machining processes and recommended machining parameters are discussed. Safety procedures and precautions necessary in machining uranium and uranium alloys are also covered. 30 figures.

Morris, T.O.

1981-12-14

331

Machine Learning and NLP Research Interests  

E-print Network

Machine Learning and NLP Research Interests Machine Learning for Language Learning and Processing University of Edinburgh keller@inf.ed.ac.uk October 15, 2008 Goldwater et al. Machine Learning for Language 1 #12;Machine Learning and NLP Research Interests 1 Machine Learning and NLP Latent Variables Multi

Edinburgh, University of

332

Machine Learning, Machine Vision, and the Brain Tomaso Poggio and Christian R. Shelton  

E-print Network

Machine Learning, Machine Vision, and the Brain Tomaso Poggio and Christian R. Shelton Center) which contribute to and complement each other. Keywords: Machine Learning, Regularization, Support Vector Machine, IT Cortex, Function Approximation, Object Detection #12; Learning Theory and Algorithms

Shelton, Christian R.

333

Machine Learning, Machine Vision, and the Brain Tomaso Poggio and Christian R. Shelton  

E-print Network

Machine Learning, Machine Vision, and the Brain Tomaso Poggio and Christian R. Shelton Center) which contribute to and complement each other. Keywords: Machine Learning, Regularization, Support Vector Machine, IT Cortex, Function Approximation, Object Detection #12;Learning Theory and Algorithms

Shelton, Christian R.

334

Autonomous Navigation for Forest Machines  

E-print Network

Inertial navigation system (INS) ..............................................................19 WheelAutonomous Navigation for Forest Machines a Pre-Study by Thomas Hellström Department of Computing Science Umeå University Umeå, Sweden 2002-10-18 #12;Autonomous Navigation for Forest Machines ­ a Pre

Hellström, Thomas

335

Machine Intelligence Alex S. Taylor  

E-print Network

Machine Intelligence Alex S. Taylor Microsoft Research 7 J. J. Thomson Avenue, Cambridge, CB3 0FB with computing machines as though they exhibited intelligence, at least an intelligence of sorts. Using exam ready to treat as intelligent. Broadly, it is suggested that ordinary, everyday ideas of intelligence

Hunt, Galen

336

Cleaning of Free Machining Brass  

SciTech Connect

We have investigated four brightening treatments proposed by two cleaning vendors for cleaning free machining brass. The experimental results showed that none of the proposed brightening treatments passed the swipe test. Thus, we maintain the recommendation of not using the brightening process in the cleaning of free machining brass for NIF application.

Shen, T

2005-12-29

337

Physics in Action: Fusion Machines  

NSDL National Science Digital Library

This article from Physics Central provides a description of fusion machines and plasma power. The process and challenges to producing a sustained fusion reaction that could lead to electric power generation are explained. Current research being conducted with fusion machines is also presented along with links to additional information.

2007-04-26

338

Parallelism in random access machines  

Microsoft Academic Search

A model of computation based on random access machines operating in parallel and sharing a common memory is presented. The computational power of this model is related to that of traditional models. In particular, deterministic parallel RAM's can accept in polynomial time exactly the sets accepted by polynomial tape bounded Turing machines; nondeterministic RAM's can accept in polynomial time exactly

Steven Fortune; James Wyllie

1978-01-01

339

Contraction-Only Exercise Machine  

NASA Technical Reports Server (NTRS)

Standard knee-extension machine modified so subject experiences force only when lifting leg against stack of weights. Exerts little force on leg while being lowered. Hydraulic cylinder and reservoir mounted on frame of exercise machine. Fluid flows freely from cylinder to reservoir during contraction (lifting) but in constricted fashion from reservoir to cylinder during extension (lowering).

Doerr, Donald F.; Maples, Arthur B.; Campbell, Craig M.

1992-01-01

340

Machine Trades Lab Management Guide.  

ERIC Educational Resources Information Center

This manual was developed to guide machine trades instructors and vocational supervisors in sequencing laboratory instruction and controlling the flow of work for a 2-year machine trades training program. The first part of the guide provides information on program management (program description, safety concerns, academic issues, implementation…

Ohio State Univ., Columbus. Instructional Materials Lab.

341

The Machine Intelligence Hex Project  

ERIC Educational Resources Information Center

Hex is a challenging strategy board game for two players. To enhance students' progress in acquiring understanding and practical experience with complex machine intelligence and programming concepts we developed the Machine Intelligence Hex (MIHex) project. The associated undergraduate student assignment is about designing and implementing Hex…

Chalup, Stephan K.; Mellor, Drew; Rosamond, Fran

2005-01-01

342

The Blindstitch Machine. Module 11.  

ERIC Educational Resources Information Center

This module on the purpose and use of the blindstitch machine, one in a series on clothing construction for industrial sewing machine operators designed for student self-study, contains three sections. Each section includes the following parts: an introduction, directions, an objective, learning activities, student information, student self-check,…

South Carolina State Dept. of Education, Columbia. Office of Vocational Education.

343

Machine-Assisted Election Auditing  

Microsoft Academic Search

Election audit procedures usually rely on precinct- based audits, in which workers manually review all paper ballots from selected polling places, but these audits can be expensive due to the labor required. This paper pro- poses an alternative audit strategy that allows machines to perform most of the work. Precincts are audited using auditing machines, and their output is manually

Joseph A. Calandrino; J. Alex Halderman; Edward W. Felten

2007-01-01

344

Cooling of new designed machine  

Microsoft Academic Search

This paper deals with aspiration to offer a special cooling system for enclosed induction machine which operates in explosive environment. This is particularly relevant to electric devices in power plant, or other predisposed applications, where machine arrangement complexity has to be kept to a minimum. A new design was developed to improve heat exchange with a low-pressure drop. A new

Vladimir Kindl; Roman Pechanek; Lukas Bouzek

2010-01-01

345

Anaesthesia machine: checklist, hazards, scavenging.  

PubMed

From a simple pneumatic device of the early 20(th) century, the anaesthesia machine has evolved to incorporate various mechanical, electrical and electronic components to be more appropriately called anaesthesia workstation. Modern machines have overcome many drawbacks associated with the older machines. However, addition of several mechanical, electronic and electric components has contributed to recurrence of some of the older problems such as leak or obstruction attributable to newer gadgets and development of newer problems. No single checklist can satisfactorily test the integrity and safety of all existing anaesthesia machines due to their complex nature as well as variations in design among manufacturers. Human factors have contributed to greater complications than machine faults. Therefore, better understanding of the basics of anaesthesia machine and checking each component of the machine for proper functioning prior to use is essential to minimise these hazards. Clear documentation of regular and appropriate servicing of the anaesthesia machine, its components and their satisfactory functioning following servicing and repair is also equally important. Trace anaesthetic gases polluting the theatre atmosphere can have several adverse effects on the health of theatre personnel. Therefore, safe disposal of these gases away from the workplace with efficiently functioning scavenging system is necessary. Other ways of minimising atmospheric pollution such as gas delivery equipment with negligible leaks, low flow anaesthesia, minimal leak around the airway equipment (facemask, tracheal tube, laryngeal mask airway, etc.) more than 15 air changes/hour and total intravenous anaesthesia should also be considered. PMID:24249887

Goneppanavar, Umesh; Prabhu, Manjunath

2013-09-01

346

Providing machine tractable dictionary tools  

Microsoft Academic Search

Machine readable dictionaries (Mrds) contain knowledge about language and the world essential for tasks in natural language processing (Nlp). However, this knowledge, collected and recorded by lexicographers for human readers, is not presented in a manner for Mrds to be used directly for Nlp tasks. What is badly needed are machine tractable dictionaries (Mtds): Mrds transformed into a format usable

Yorick Wilks; Dan Fass; Cheng-ming Guo; James E. Mcdonald; Tony Plate; Brian M. Slator

1990-01-01

347

TEACHING MACHINE STUDY. FINAL REPORT.  

ERIC Educational Resources Information Center

IN AN INVESTIGATION OF THE POTENTIAL OF TEACHING MACHINES IN THE JOB CORPS MATHEMATICS PROGRAM, EXISTING JOB CORPS ARITHMETIC MATERIAL WAS PREPARED FOR INSTRUCTION BY MACHINE AND PROGRAMED TEXT, AND THEN FIELD TESTED. REVISIONS WERE MADE, AND A PROGRAMED MANUAL FOR INSTRUCTORS WRITTEN, AFTER WHICH A NEW FIELD TEST WAS RUN. IN THE INITIAL FIELD…

EVCO, Albuquerque, NM.

348

Safety Features in Anaesthesia Machine  

PubMed Central

Anaesthesia is one of the few sub-specialties of medicine, which has quickly adapted technology to improve patient safety. This application of technology can be seen in patient monitoring, advances in anaesthesia machines, intubating devices, ultrasound for visualisation of nerves and vessels, etc., Anaesthesia machines have come a long way in the last 100 years, the improvements being driven both by patient safety as well as functionality and economy of use. Incorporation of safety features in anaesthesia machines and ensuring that a proper check of the machine is done before use on a patient ensures patient safety. This review will trace all the present safety features in the machine and their evolution. PMID:24249880

Subrahmanyam, M; Mohan, S

2013-01-01

349

Machinability of Stellite 6 hardfacing  

NASA Astrophysics Data System (ADS)

This paper reports some experimental findings concerning the machinability at high cutting speed of nickel-base weld-deposited hardfacings for the manufacture of hot tooling. The forging work involves extreme impacts, forces, stresses and temperatures. Thus, mould dies must be extremely resistant. The aim of the project is to create a rapid prototyping process answering to forging conditions integrating a Stellite 6 hardfacing deposed PTA process. This study talks about the dry machining of the hardfacing, using a two tips machining tool and a high speed milling machine equipped by a power consumption recorder Wattpilote. The aim is to show the machinability of the hardfacing, measuring the power and the tip wear by optical microscope and white light interferometer, using different strategies and cutting conditions.

Benghersallah, M.; Boulanouar, L.; Le Coz, G.; Devillez, A.; Dudzinski, D.

2010-06-01

350

Finite State Machines Testing problems Conformance Testing Machine Identification FSM-Based Testing  

E-print Network

Finite State Machines Testing problems Conformance Testing Machine Identification FSM-Based Testing Mousavi: FSM-Based Testing Part II #12;Finite State Machines Testing problems Conformance Testing Machine Identification Outline Finite State Machines Testing problems Conformance Testing Machine Identification Mousavi

Mousavi, Mohammad

351

A study on the machining-parameters optimization of wire electrical discharge machining  

Microsoft Academic Search

A suitable selection of machining parameters for the wire electrical discharge machining (WEDM) process relies heavily on the operators' technologies and experience because of their numerous and diverse range. Machining-parameters tables provided by the machine-tool builder can not meet the operators' requirements, since for an arbitrary desired roughness of the machining surface, they do not provide the optimal machining conditions.

Y. S. Liao; J. T. Huang; H. C. Su

1997-01-01

352

Machine Vision Preis Vielseitig, wachstumsstark und zukunftssicher  

E-print Network

Machine Vision Preis Vielseitig, wachstumsstark und zukunftssicher: Sehende Maschinen! Jetzt den richtigen Weg einschlagen, Machine Vision zu deinem Thema machen und die Chance zum Erfolg nutzen beim: Machine Vision, also sehende Systeme, die das menschliche Auge nachahmen, stellen eine moderne

Haller-Dintelmann, Robert

353

49 CFR 173.174 - Refrigerating machines.  

Code of Federal Regulations, 2012 CFR

...2012-10-01 2012-10-01 false Refrigerating machines. 173.174 Section 173.174 Transportation...Class 1 and Class 7 § 173.174 Refrigerating machines. A refrigerating machine assembled for shipment and containing 7 kg...

2012-10-01

354

48 CFR 908.7103 - Office machines.  

Code of Federal Regulations, 2013 CFR

...2013-10-01 2013-10-01 false Office machines. 908.7103 Section 908.7103 Federal...Acquisition of Special Items 908.7103 Office machines. Acquisitions of office machines by DOE offices and its authorized...

2013-10-01

355

7 CFR 58.429 - Washing machine.  

Code of Federal Regulations, 2011 CFR

...2011-01-01 2011-01-01 false Washing machine. 58.429 Section 58.429 Agriculture...Equipment and Utensils § 58.429 Washing machine. When used, the washing machine for cheese cloths and bandages shall be...

2011-01-01

356

49 CFR 173.174 - Refrigerating machines.  

Code of Federal Regulations, 2011 CFR

...2011-10-01 2011-10-01 false Refrigerating machines. 173.174 Section 173.174 Transportation...Class 1 and Class 7 § 173.174 Refrigerating machines. A refrigerating machine assembled for shipment and containing 7 kg...

2011-10-01

357

29 CFR 1917.151 - Machine guarding.  

Code of Federal Regulations, 2013 CFR

...2013-07-01 2013-07-01 false Machine guarding. 1917.151 Section 1917...Operations and Equipment § 1917.151 Machine guarding. (a) Definition...b) General. (1) Danger zones on machines and equipment used by employees...

2013-07-01

358

7 CFR 58.429 - Washing machine.  

Code of Federal Regulations, 2013 CFR

...2013-01-01 2013-01-01 false Washing machine. 58.429 Section 58.429 Agriculture...Equipment and Utensils § 58.429 Washing machine. When used, the washing machine for cheese cloths and bandages shall be...

2013-01-01

359

29 CFR 1917.151 - Machine guarding.  

Code of Federal Regulations, 2011 CFR

...2011-07-01 2011-07-01 false Machine guarding. 1917.151 Section 1917...Operations and Equipment § 1917.151 Machine guarding. (a) Definition...b) General. (1) Danger zones on machines and equipment used by employees...

2011-07-01

360

48 CFR 908.7103 - Office machines.  

Code of Federal Regulations, 2011 CFR

...2011-10-01 2011-10-01 false Office machines. 908.7103 Section 908.7103 Federal...Acquisition of Special Items 908.7103 Office machines. Acquisitions of office machines by DOE offices and its authorized...

2011-10-01

361

48 CFR 908.7103 - Office machines.  

Code of Federal Regulations, 2012 CFR

...2012-10-01 2012-10-01 false Office machines. 908.7103 Section 908.7103 Federal...Acquisition of Special Items 908.7103 Office machines. Acquisitions of office machines by DOE offices and its authorized...

2012-10-01

362

7 CFR 58.429 - Washing machine.  

...2014-01-01 2014-01-01 false Washing machine. 58.429 Section 58.429 Agriculture...Equipment and Utensils § 58.429 Washing machine. When used, the washing machine for cheese cloths and bandages shall be...

2014-01-01

363

49 CFR 173.174 - Refrigerating machines.  

Code of Federal Regulations, 2013 CFR

...2013-10-01 2013-10-01 false Refrigerating machines. 173.174 Section 173.174 Transportation...Class 1 and Class 7 § 173.174 Refrigerating machines. A refrigerating machine assembled for shipment and containing 7 kg...

2013-10-01

364

7 CFR 58.429 - Washing machine.  

Code of Federal Regulations, 2012 CFR

...2012-01-01 2012-01-01 false Washing machine. 58.429 Section 58.429 Agriculture...Equipment and Utensils § 58.429 Washing machine. When used, the washing machine for cheese cloths and bandages shall be...

2012-01-01

365

Machine Learning ! ! ! ! !Srihari Convolutional Networks and Soft-  

E-print Network

! · Convolutional Networks! · Soft-weight sharing! 2 #12;Machine Learning ! ! ! ! !Srihari Limitations of Neural #12;Machine Learning ! ! ! ! !Srihari Three Mechanisms of Convolutional Neural Networks! 1. LocalMachine Learning ! ! ! ! !Srihari Convolutional Networks and Soft- weight sharing ! Sargur Srihari

366

Machine Vision Online: Tips for Successfully Applying Machine Vision  

NSDL National Science Digital Library

This Web site provides many articles and educational resources related to machine vision. Most of the materials come from companies with significant experience with the topic, including Ford Motor Company, Adept Technology, and many others. Visitors to the site can read about the basics of machine vision and learn how to successfully implement and design a system. Inexperienced people should start with the Strategies for New Users section, which contains a glossary of terms and a couple brief introductions. The Technical Papers section has information on the various components of a machine vision system, and Applications by Industry has case studies of several different operations.

367

A Boltzmann machine for the organization of intelligent machines  

NASA Technical Reports Server (NTRS)

A three-tier structure consisting of organization, coordination, and execution levels forms the architecture of an intelligent machine using the principle of increasing precision with decreasing intelligence from a hierarchically intelligent control. This system has been formulated as a probabilistic model, where uncertainty and imprecision can be expressed in terms of entropies. The optimal strategy for decision planning and task execution can be found by minimizing the total entropy in the system. The focus is on the design of the organization level as a Boltzmann machine. Since this level is responsible for planning the actions of the machine, the Boltzmann machine is reformulated to use entropy as the cost function to be minimized. Simulated annealing, expanding subinterval random search, and the genetic algorithm are presented as search techniques to efficiently find the desired action sequence and illustrated with numerical examples.

Moed, Michael C.; Saridis, George N.

1990-01-01

368

Lubrication of Machine Elements  

NASA Technical Reports Server (NTRS)

The understanding of hydrodynamic lubrication began with the classical experiments of Tower and Petrov. Reynolds used a reduced form of the Navier-Stokes equations and the continuity equation to generate a second order differential equation for the pressure in the narrow, converging gap of a bearing contact. Such a pressure enables a load to be transmitted between the surfaces with very low friction since the surfaces are completely separated by a film of fluid. In such a situation it is the physical properties of the lubricant, notably the dynamic viscosity, that dictate the behavior of the contact. The understanding of boundary lubrication is normally attributed to Hardy and Doubleday. In boundary lubrication it is the physical and chemical properties of thin films of molecular proportions and the surfaces to which they are attached that determine contact behavior. The lubricant viscosity is not an influential parameter. Research is devoted to a better understanding and more precise definition of other lubrication regimes between these extremes. One such regime, elastohydrodynamic lubrication, occurs in nonconformal contacts, where the pressures are high and the bearing surfaces deform elastically. In this situation the viscosity of the lubricant may raise considerably, and this further assists the formation of an effective fluid film. The science of these three lubrication regimes (hydrodynamic, elastohydrodynamic, and boundary) are described and the manner in which this science is used in the design of machine elements is examined.

Hamrock, B. J.

1984-01-01

369

Frozen beverage machine  

SciTech Connect

A frozen beverage machine is described, comprising: a. a frame having an exterior, an interior, a front and a back; b. a cylinder, having an interior and an exterior as well as first and second ends and further having an opening in each of the ends, the cylinder being horizontally and fixedly positioned within the interior of the frame with the second end facing the front of the frame; c. a means, sealingly attached to the opening in the second end of the cylinder, for emptying the cylinder; d. a means, positioned within the frame and communicating with the exterior of the cylinder, for removing heat from the cylinder; e. at least one support bracket; f. a shaft, rotatably attached within the opening in the support bracket and rotatably and sealingly attached within the opening in the first end of the cylinder and extending to the interior of the cylinder; g. a motor assembly, operatively connected to a portion of the shaft exterior to the cylinder and suspended from the shaft such that the weight of the motor assembly is supported only by the shaft; h. a contact switch; and i. a resilient means, connected to the frame and the motor assembly, for maintaining the position of the motor assembly relative to the shaft until a desired threshold resistance to rotation of the shaft within the cylinder occur, and then allowing the motor assembly to rotate to a desired position relative to the shaft.

Williams, J.D.

1988-04-12

370

Size reduction machine  

SciTech Connect

The Size Reduction Machine (SRM) is a mobile platform capable of shearing various shapes and types of metal components at a variety of elevations. This shearing activity can be performed without direct physical movement and placement of the shear head by the operator. The base unit is manually moved and roughly aligned to each cut location. The base contains the electronics: hydraulic pumps, servos, and actuators needed to move the shear-positioning arm. The movable arm allows the shear head to have six axes of movement and to cut to within 4 inches of a wall surface. The unit has a slick electrostatic capture coating to assist in external decontamination. Internal contamination of the unit is controlled by a high-efficiency particulate air (HEPA) filter on the cooling inlet fan. The unit is compact enough to access areas through a 36-inch standard door opening. This paper is an Innovative Technology Summary Report designed to provide potential users with the information they need to quickly determine if a technology would apply to a particular environmental management problem. They also are designed for readers who may recommend that a technology be considered by prospective users.

Fricke, V.

1999-12-15

371

Solid waste comminution machine  

SciTech Connect

A solid waste comminution machine is described of the type having two sets of interleaving wheels, including a lower set and an upper set of wheel members. Each set includes a pair of shafts on which the wheel members are mounted, the pairs of shafts mounted on upright, mutually facing, movable arms. The improvement consists of: the upper set of wheel members having ripping and shearing tools attached to the circumferential periphery of the wheel members, the pair of shafts associated with the upper set of wheel members mounted on the movable arms, the lower set of wheel members mounted on a pair of fixed, parallel shafts, the shafts supported at one end of the arms with the lower set of wheel members interleaving in a material shearing relation. The shafts form a fixed pivot axis for the arms, the arms having fixed lengths with inward and outward ends, the outward ends extending beyond the shafts associated with the upper set of wheels thereby forming leverage regions, and hydraulic piston means having fixed ends and free ends, the free ends connected to the leverage regions for bringing the arms toward each other to a point at which the upper set of wheels mesh with sufficient force to enable ripping of material between the upper set of wheels.

Barclay, R.L.

1986-08-26

372

Video time encoding machines.  

PubMed

We investigate architectures for time encoding and time decoding of visual stimuli such as natural and synthetic video streams (movies, animation). The architecture for time encoding is akin to models of the early visual system. It consists of a bank of filters in cascade with single-input multi-output neural circuits. Neuron firing is based on either a threshold-and-fire or an integrate-and-fire spiking mechanism with feedback. We show that analog information is represented by the neural circuits as projections on a set of band-limited functions determined by the spike sequence. Under Nyquist-type and frame conditions, the encoded signal can be recovered from these projections with arbitrary precision. For the video time encoding machine architecture, we demonstrate that band-limited video streams of finite energy can be faithfully recovered from the spike trains and provide a stable algorithm for perfect recovery. The key condition for recovery calls for the number of neurons in the population to be above a threshold value. PMID:21296708

Lazar, Aurel A; Pnevmatikakis, Eftychios A

2011-03-01

373

Video Time Encoding Machines  

PubMed Central

We investigate architectures for time encoding and time decoding of visual stimuli such as natural and synthetic video streams (movies, animation). The architecture for time encoding is akin to models of the early visual system. It consists of a bank of filters in cascade with single-input multi-output neural circuits. Neuron firing is based on either a threshold-and-fire or an integrate-and-fire spiking mechanism with feedback. We show that analog information is represented by the neural circuits as projections on a set of band-limited functions determined by the spike sequence. Under Nyquist-type and frame conditions, the encoded signal can be recovered from these projections with arbitrary precision. For the video time encoding machine architecture, we demonstrate that band-limited video streams of finite energy can be faithfully recovered from the spike trains and provide a stable algorithm for perfect recovery. The key condition for recovery calls for the number of neurons in the population to be above a threshold value. PMID:21296708

Lazar, Aurel A.; Pnevmatikakis, Eftychios A.

2013-01-01

374

Slide system for machine tools  

DOEpatents

The present invention relates to a machine tool which permits the machining of nonaxisymmetric surfaces on a workpiece while rotating the workpiece about a central axis of rotation. The machine tool comprises a conventional two-slide system (X-Y) with one of these slides being provided with a relatively short travel high-speed auxiliary slide which carries the material-removing tool. The auxiliary slide is synchronized with the spindle speed and the position of the other two slides and provides a high-speed reciprocating motion required for the displacement of the cutting tool for generating a nonaxisymmetric surface at a selected location on the workpiece.

Douglass, Spivey S. (Oak Ridge, TN); Green, Walter L. (Knoxville, TN)

1982-01-01

375

Gradient boosting machines, a tutorial  

PubMed Central

Gradient boosting machines are a family of powerful machine-learning techniques that have shown considerable success in a wide range of practical applications. They are highly customizable to the particular needs of the application, like being learned with respect to different loss functions. This article gives a tutorial introduction into the methodology of gradient boosting methods with a strong focus on machine learning aspects of modeling. A theoretical information is complemented with descriptive examples and illustrations which cover all the stages of the gradient boosting model design. Considerations on handling the model complexity are discussed. Three practical examples of gradient boosting applications are presented and comprehensively analyzed. PMID:24409142

Natekin, Alexey; Knoll, Alois

2013-01-01

376

Toward Machine Therapy: Parapraxis of Machine Design and Use  

Microsoft Academic Search

Machine Therapy is a new methodology combining art, design, psychodynamics, and engineering work in ways that access and reveal\\u000a the vital relevance of subconscious elements of human-machine interactions. In this paper I present examples of empathic relationships\\u000a with domestic appliances, roles of wearable and prosthetic apparatuses, and instances of evocative visceral robots that interact\\u000a with people’s understandings of themselves and

Kelly Dobson

2007-01-01

377

INTRODUCTION TO MACHINING 1.2 MILLING MACHINE  

E-print Network

of producing flat, angled or curved surfaces (or a combination thereof), depending on the type(s) of tool(s-axis machines when the table can move in the x and y directions and the tool in the z TO MACHINING Based on Figures 1.2.1 1 and 1.2.2: Spindle and quill: the spindle holds the tool-holding device

Sun, Yu

378

Machine Learning via Mathematical Programming.  

National Technical Information Service (NTIS)

Mathematical programming approaches were applied to a variety of problems in machine learning in order to gain deeper understanding of the problems and to come up with new and more efficient computational algorithms. Theoretical and/or computational contr...

O. L. Mamgasarian

1999-01-01

379

Machine Learning Methods for Bioinformatics  

E-print Network

? Bill Gates: If you design a machine that can learn, it is worth 10 Microsoft. (e.g., Google, Apple) #12, or the president of Microsoft? · Bill Gates: I view myself a software engineer. Business is not complicated

Cheng, Jianlin Jack

380

The ideal home hemodialysis machine.  

PubMed

Daily home hemodialysis (HD) patients have a much superior survival rate than patients on regular, 3 times a week in-center HD or on peritoneal dialysis. Present-day HD machines are unsuitable for use at home by patients. We present our concept of the ideal home HD machine that allows daily short and long HD, does all the work preparing for and cleaning up after dialysis, has an intravenous infusion system controlled by the patient, needs no systemic anticoagulation, and teaches and interacts with the patient during dialysis. To fulfill these functionalities, the dialyzer and blood tubing must be integrated with the machine and replaced less often than monthly, the machine must be capable of at least 200 L/week of hemodiafiltration, prepare all fluids necessary between and during dialyses, and all the components and fluids must be much beyond ultrapure. PMID:18638239

Kjellstrand, Carl M; Kjellstrand, Per

2008-07-01

381

Time Machine at the LHC  

E-print Network

Recently, black hole and brane production at CERN's Large Hadron Collider (LHC) has been widely discussed. We suggest that there is a possibility to test causality at the LHC. We argue that if the scale of quantum gravity is of the order of few TeVs, proton-proton collisions at the LHC could lead to the formation of time machines (spacetime regions with closed timelike curves) which violate causality. One model for the time machine is a traversable wormhole. We argue that the traversable wormhole production cross section at the LHC is of the same order as the cross section for the black hole production. Traversable wormholes assume violation of the null energy condition (NEC) and an exotic matter similar to the dark energy is required. Decay of the wormholes/time machines and signatures of time machine events at the LHC are discussed.

I. Ya. Aref'eva; I. V. Volovich

2007-10-15

382

Diamond turning machine controller implementation  

SciTech Connect

The standard controller for a Pnuemo ASG 2500 Diamond Turning Machine, an Allen Bradley 8200, has been replaced with a custom high-performance design. This controller consists of four major components. Axis position feedback information is provided by a Zygo Axiom 2/20 laser interferometer with 0.1 micro-inch resolution. Hardware interface logic couples the computers digital and analog I/O channels to the diamond turning machine`s analog motor controllers, the laser interferometer, and other machine status and control information. It also provides front panel switches for operator override of the computer controller and implement the emergency stop sequence. The remaining two components, the control computer hardware and software, are discussed in detail below.

Garrard, K.P.; Taylor, L.W.; Knight, B.F.; Fornaro, R.J.

1988-12-01

383

Development of Electrochemical Micro Machining  

E-print Network

at the cathode and the burrs ............................................ 11 5 Hole drilling using ECM ............................................................................ 12 6 Shape of tool and cavity formed after machining... in the effective removal of metal ions between anode and cathode and it offers good control of the etched surface. The feedback loop is to be designed in such a way that the system detects variations in the current in machining zone and automatically compensates...

Srinivas Sundarram, Sriharsha

2008-10-10

384

Building and simulating protein machines  

NASA Astrophysics Data System (ADS)

Glycolysis is a central metabolic pathway, present in almost all organisms, that produces energy. The pathway has been extensively investigated by biochemists. There is a significant body of structural and biochemical information about this pathway. The complete pathway is a ten step process. At each step, a specific chemical reaction is catalyzed by a specific enzyme. Fructose bisphosphate aldolase (FBA) and triosephosphate isomerase (TIM) catalyze the fourth and the fifth steps on the pathway. This thesis investigates the possible substrate transfer mechanism between FBA and TIM. FBA cleaves its substrate, the six-carbon fructose-1,6-bisphosphate (FBP), into two three-carbon products -- glyceraldehydes 3-phosphate (GAP) and dihydroxy acetone phosphate (DHAP). One component of these two products, DHAP, is the substrate for TIM and the other component GAP goes directly to GAPDH, the subsequent enzyme on the pathway. TIM converts DHAP to GAP and delivers the product to GAPDH. I employ Elastic Network Models (ENM) to investigate the mechanistic and dynamic aspects of the functionality of FBA and TIM enzymes -- (1) the effects of the oligomerization of these two enzymes on their functional dynamics and the coordination of the individual protein's structural components along the functional region; and (2) the mechanistic synchrony of these two protein machines that may enable them to operate in a coordinated fashion as a conjugate machine -- transferring the product from FBA as substrate to TIM. A macromolecular machine comprised of FBA and TIM will facilitate the substrate catalysis mechanism and the product flow between FBA and TIM. Such a machine could be used as a functional unit in building a larger a machine for the structural modeling of the whole glycolysis pathway. Building such machines for the glycolysis pathway may reveal the interplay of the enzymes as a complete machine. Also the methods and insights developed from the efforts to build such large machines could be applied to build macromolecular structures for other biologically important clusters of interacting enzymes centered around individual metabolic pathways.

Katebi, Ataur Rahim

385

Gaussian processes for machine learning.  

PubMed

Gaussian processes (GPs) are natural generalisations of multivariate Gaussian random variables to infinite (countably or continuous) index sets. GPs have been applied in a large number of fields to a diverse range of ends, and very many deep theoretical analyses of various properties are available. This paper gives an introduction to Gaussian processes on a fairly elementary level with special emphasis on characteristics relevant in machine learning. It draws explicit connections to branches such as spline smoothing models and support vector machines in which similar ideas have been investigated. Gaussian process models are routinely used to solve hard machine learning problems. They are attractive because of their flexible non-parametric nature and computational simplicity. Treated within a Bayesian framework, very powerful statistical methods can be implemented which offer valid estimates of uncertainties in our predictions and generic model selection procedures cast as nonlinear optimization problems. Their main drawback of heavy computational scaling has recently been alleviated by the introduction of generic sparse approximations.13,78,31 The mathematical literature on GPs is large and often uses deep concepts which are not required to fully understand most machine learning applications. In this tutorial paper, we aim to present characteristics of GPs relevant to machine learning and to show up precise connections to other "kernel machines" popular in the community. Our focus is on a simple presentation, but references to more detailed sources are provided. PMID:15112367

Seeger, Matthias

2004-04-01

386

Risk estimation using probability machines  

PubMed Central

Background Logistic regression has been the de facto, and often the only, model used in the description and analysis of relationships between a binary outcome and observed features. It is widely used to obtain the conditional probabilities of the outcome given predictors, as well as predictor effect size estimates using conditional odds ratios. Results We show how statistical learning machines for binary outcomes, provably consistent for the nonparametric regression problem, can be used to provide both consistent conditional probability estimation and conditional effect size estimates. Effect size estimates from learning machines leverage our understanding of counterfactual arguments central to the interpretation of such estimates. We show that, if the data generating model is logistic, we can recover accurate probability predictions and effect size estimates with nearly the same efficiency as a correct logistic model, both for main effects and interactions. We also propose a method using learning machines to scan for possible interaction effects quickly and efficiently. Simulations using random forest probability machines are presented. Conclusions The models we propose make no assumptions about the data structure, and capture the patterns in the data by just specifying the predictors involved and not any particular model structure. So they do not run the same risks of model mis-specification and the resultant estimation biases as a logistic model. This methodology, which we call a “risk machine”, will share properties from the statistical machine that it is derived from. PMID:24581306

2014-01-01

387

pdf version of the entry Time Machines  

E-print Network

pdf version of the entry Time Machines http://plato.stanford.edu/archives/win2010/entries/time-machine, Stanford, CA 94305 Time Machines Copyright c 2010 by the authors John Earman and Christian W¨uthrich All rights reserved. Copyright policy: https://leibniz.stanford.edu/friends/info/copyright/ Time Machines

Wüthrich, Christian

388

Electrode Wear Process in Electrical Discharge Machinings  

Microsoft Academic Search

This paper deals with a synthetic consideration of electrode wear phenomena in electrical discharge machining. Time dependance of an electrode shape was observed through on-the-machine measurement. While the electrode wears at the edge portion in the beginning of machining, it grows at the flat portion in the longitudinal direction. In the stationary state of machining, the wear rate of an

Naotake Mohri; Masayuki Suzuki; Masanori Furuya; Nagao Saito; Akira Kobayashi

1995-01-01

389

Standard Operating Procedure (SOP) -Milling Machine  

E-print Network

Standard Operating Procedure (SOP) - Milling Machine · Keep all guards in place while operating the machine. · While operating the milling machine allow no one else to touch it. · Keep hands away from moving cutting tools. · Do not make measurements of the stock while the milling machine is powered. · Do

Veiga, Pedro Manuel Barbosa

390

Machinability of phosphorous containing sintered steels  

Microsoft Academic Search

Study of the machinability characteristics of porous sintered materials has received far less attention during the last decades, presumably due to powder metallurgy’s greatest advantage over other manufacturing methods in eliminating completely or minimising greatly machining and also perhaps due to lack of any standard test method developed for machinability studies. However, many parts because of intricate design, require machining

Mohammad Hamiuddin; Qasim Murtaza

2001-01-01

391

Modeling and Application of Virtual Machine Tool  

Microsoft Academic Search

The recent years of the 21th Century are associated with the advent of virtual reality technologies for modern industry and manufacturing engineering. Virtual Machine Tool Technology is given to design, test, control and machine parts in a virtual reality environment. This paper presents the methods to model and simulate the virtual machine tools in response to change in the machining

Weiqing Lin; Jianzhong Fu

2006-01-01

392

An introducWon to Machine Learning  

E-print Network

An introducWon to Machine Learning Pierre Geurts p.geurts@ulg.ac.be Department of EE and CS Other learning protocols/frameworks #12;3 Machine Learning: definiWon Machine Learning is concernedWon and beXer understand the system #12;4 Machine learning: when ? Learning is useful when: Human

Wehenkel, Louis

393

Autonomous agent for on-machine acceptance of machined components  

NASA Astrophysics Data System (ADS)

In recent years, manufacturers of high precision mechanical parts have been required to produce increasingly complex designs, in smaller lot sizes, with improved quality. These requirements demand lower process costs, shorter development cycles and more accurate manufacturing technologies. To meet these demands, manufacturers are attempting to both improve process quality and provide better CAD/CAM integration. The technique of on- machine acceptance provides one mechanisms for improving the part inspection and verification process. This approach allows one machine and one process capability model to be used for both fabrication and inspection, reducing capital cost and overall cycle time. However, the on-machine acceptance technique possesses greater potential than as simply an alternative mechanism for verifying part geometry. If the inspection capability information generated by on-machine acceptance processes can be made available to designers, it can be used to create a design-for-inspectability environment and help realize the benefits of concurrent engineering. This paper proposes a novel architecture which integrates on-machine acceptance with an agent-based concurrent design environment, for reducing both the cost and production time for high quality, small lot size, mechanical parts. This work has focused on the production of stainless steel pressure vessels at the Integrated Manufacturing Technology Laboratory manufacturing cell, located at Sandia National Laboratories, California.

Pancerella, Carmen M.; Hazelton, Andrew J.; Frost, H. R.

1995-11-01

394

Semi-online machine covering for two uniform machines Xingyu Chen  

E-print Network

as to maximize the completion time of the least loaded machine. We study a semi-online variant, where jobs arriveSemi-online machine covering for two uniform machines Xingyu Chen Leah Epstein Zhiyi Tan Abstract The machine covering problem deals with partitioning a sequence of jobs among a set of machines, so

Epstein, Leah

395

A new breed of electric machines - basic analysis and applications of dual mechanical port electric machines  

Microsoft Academic Search

Conceptually, mechanical port of an electric machine can be doubled and the concept of dual-mechanical-port (DMP) will then give birth to a new breed of electric machines. In this paper, the various possible structures of DMP electric machine are discussed. Basic modeling and analysis issues related to the DMP electric machine are presented. An exemplary design of DMP machine is

Longya Xu

2005-01-01

396

programme in Machine Machine Learning is an area within Computer Science where  

E-print Network

Master's programme in Machine Learning Machine Learning is an area within Computer Science where of biological systems (like humans). Recently, Machine Learning has gained great importance for the design. The focus of the Master's program in Machine Learning is on mathematical foundations and methods for Machine

Kjellström, Hedvig

397

Student Perceptions of the Shift from Soft Drink Vending Machines to Milk Vending Machines in Schools  

Microsoft Academic Search

Soft drink vending machines are available in many schools across the nation. Some schools have recently removed soft drink vending machines and replaced them with milk vending machines. The purpose of this study was to investigate high school students’ (n = 84) perceptions of the shift from soft drink vending machines to milk vending machines in schools.\\u000aStudents in this

Jillian B Trapini

2007-01-01

398

Game-powered machine learning.  

PubMed

Searching for relevant content in a massive amount of multimedia information is facilitated by accurately annotating each image, video, or song with a large number of relevant semantic keywords, or tags. We introduce game-powered machine learning, an integrated approach to annotating multimedia content that combines the effectiveness of human computation, through online games, with the scalability of machine learning. We investigate this framework for labeling music. First, a socially-oriented music annotation game called Herd It collects reliable music annotations based on the "wisdom of the crowds." Second, these annotated examples are used to train a supervised machine learning system. Third, the machine learning system actively directs the annotation games to collect new data that will most benefit future model iterations. Once trained, the system can automatically annotate a corpus of music much larger than what could be labeled using human computation alone. Automatically annotated songs can be retrieved based on their semantic relevance to text-based queries (e.g., "funky jazz with saxophone," "spooky electronica," etc.). Based on the results presented in this paper, we find that actively coupling annotation games with machine learning provides a reliable and scalable approach to making searchable massive amounts of multimedia data. PMID:22460786

Barrington, Luke; Turnbull, Douglas; Lanckriet, Gert

2012-04-24

399

Game-powered machine learning  

PubMed Central

Searching for relevant content in a massive amount of multimedia information is facilitated by accurately annotating each image, video, or song with a large number of relevant semantic keywords, or tags. We introduce game-powered machine learning, an integrated approach to annotating multimedia content that combines the effectiveness of human computation, through online games, with the scalability of machine learning. We investigate this framework for labeling music. First, a socially-oriented music annotation game called Herd It collects reliable music annotations based on the “wisdom of the crowds.” Second, these annotated examples are used to train a supervised machine learning system. Third, the machine learning system actively directs the annotation games to collect new data that will most benefit future model iterations. Once trained, the system can automatically annotate a corpus of music much larger than what could be labeled using human computation alone. Automatically annotated songs can be retrieved based on their semantic relevance to text-based queries (e.g., “funky jazz with saxophone,” “spooky electronica,” etc.). Based on the results presented in this paper, we find that actively coupling annotation games with machine learning provides a reliable and scalable approach to making searchable massive amounts of multimedia data. PMID:22460786

Barrington, Luke; Turnbull, Douglas; Lanckriet, Gert

2012-01-01

400

Minimal universal quantum heat machine  

E-print Network

In traditional thermodynamics the Carnot cycle yields the ideal performance bound of heat engines and refrigerators. We propose and analyze a minimal model of a heat machine that can play a similar role in quantum regimes. The minimal model consists of a single two-level system with periodically modulated energy splitting that is permanently, weakly, coupled to two spectrally-separated heat baths at different temperatures. The equation of motion allows to compute the stationary power and heat currents in the machine consistently with the second-law of thermodynamics. This dual-purpose machine can act as either an engine or a refrigerator (heat pump) depending on the modulation rate. In both modes of operation the maximal Carnot efficiency is reached at zero power. We study the conditions for finite-time optimal performance for several variants of the model. Possible realizations of the model are discussed.

David Gelbwaser-Klimovsky; Robert Alicki; Gershon Kurizki

2012-09-06

401

Alpha Channeling in Mirror Machines  

SciTech Connect

Because of their engineering simplicity, high-?, and steady-state operation, mirror machines and related open-trap machines such as gas dynamic traps, are an attractive concept for achieving controlled nuclear fusion. In these open-trap machines, the confinement occurs by means of magnetic mirroring, without the magnetic field lines closing upon themselves within the region of particle confinement. Unfortunately, these concepts have not achieved to date very spectacular laboratory results, and their reactor prospects are dimmed by the prospect of a low Q-factor, the ratio of fusion power produced to auxiliary power. Nonetheless, because of its engineering promise, over the years numerous improvements have been proposed to enhance the reactor prospects of mirror fusion, such as tandem designs, end-plugging, and electric potential barriers.

Fisch N.J.

2005-10-19

402

Simple Machines in the Community  

NSDL National Science Digital Library

The community can be a powerful context and mini-laboratory for cultivating students' common understandings of science and mathematics. On the island of Panay in the Philippines, the community was the starting place for a group of fifth- and sixth-grade students to explore simple machines in their daily lives. What students learned in the process became the basis for developing the set of culturally relevant lessons on simple machines described in this article. Each of the examples that follow features a simple machine found in the community, an explanation of how it works, a guiding-inquiry question, and a follow-up activity designed to foster students' exploration of this question.

Laroder, Aris; Tippens, Deborah; Meliza (Melai) Emaz; Bryan, Robert; Fox, Ryan

2008-03-01

403

Machine learning methods in chemoinformatics  

PubMed Central

Machine learning algorithms are generally developed in computer science or adjacent disciplines and find their way into chemical modeling by a process of diffusion. Though particular machine learning methods are popular in chemoinformatics and quantitative structure–activity relationships (QSAR), many others exist in the technical literature. This discussion is methods-based and focused on some algorithms that chemoinformatics researchers frequently use. It makes no claim to be exhaustive. We concentrate on methods for supervised learning, predicting the unknown property values of a test set of instances, usually molecules, based on the known values for a training set. Particularly relevant approaches include Artificial Neural Networks, Random Forest, Support Vector Machine, k-Nearest Neighbors and naïve Bayes classifiers.

Mitchell, John B. O.

2014-01-01

404

Thermoacoustic simulator for regenerative machines  

NASA Astrophysics Data System (ADS)

Linear thermoacoustic theory is a powerful tool to understand the working mechanism of many regenerative machines. Based on the theory, the authors have developed a computer code "Thermoacoustic Simulator" for analyzing and designing different regenerative cryocoolers including String refrigerators, Stirling and G-M types of pulse tube refrigerators and G-M cryocoolers. Also, standing-wave and traveling-wave thermoacoustic machines can be simulated, too. This paper will present the philosophy of the "Thermoacoustic Simulator" and some demonstrations of simulation for different types of cryocoolers and thermoacoustic engines.

Luo, E.; Wu, J.; Yang, J.; Xiao, J.

2002-05-01

405

Cooling system for rotating machine  

DOEpatents

An electrical machine comprising a rotor is presented. The electrical machine includes the rotor disposed on a rotatable shaft and defining a plurality of radial protrusions extending from the shaft up to a periphery of the rotor. The radial protrusions having cavities define a fluid path. A stationary shaft is disposed concentrically within the rotatable shaft wherein an annular space is formed between the stationary and rotatable shaft. A plurality of magnetic segments is disposed on the radial protrusions and the fluid path from within the stationary shaft into the annular space and extending through the cavities within the radial protrusions.

Gerstler, William Dwight (Niskayuna, NY); El-Refaie, Ayman Mohamed Fawzi (Niskayuna, NY); Lokhandwalla, Murtuza (Clifton Park, NY); Alexander, James Pellegrino (Ballston Lake, NY); Quirion, Owen Scott (Clifton Park, NY); Palafox, Pepe (Schenectady, NY); Shen, Xiaochun (Schenectady, NY); Salasoo, Lembit (Schenectady, NY)

2011-08-09

406

Exploring Machin's Approximation of Exploring Machin's Approximation of  

E-print Network

#12;Exploring Machin's Approximation of Precursors Method of Exhaustion `a la Archimedes Archimedes of Precursors Method of Exhaustion `a la Archimedes Archimedes of Syracuse ( 287­212 BC) approximated la Archimedes Archimedes of Syracuse ( 287­212 BC) approximated by the Method of Exhaustion: 3

Knaust, Helmut

407

The Perfect Science Machine  

NASA Astrophysics Data System (ADS)

ESO celebrates 10 years since First Light of the VLT Today marks the 10th anniversary since First Light with ESO's Very Large Telescope (VLT), the most advanced optical telescope in the world. Since then, the VLT has evolved into a unique suite of four 8.2-m Unit Telescopes (UTs) equipped with no fewer than 13 state-of-the-art instruments, and four 1.8-m moveable Auxiliary Telescopes (ATs). The telescopes can work individually, and they can also be linked together in groups of two or three to form a giant 'interferometer' (VLTI), allowing astronomers to see details corresponding to those from a much larger telescope. Green Flash at Paranal ESO PR Photo 16a/08 The VLT 10th anniversary poster "The Very Large Telescope array is a flagship facility for astronomy, a perfect science machine of which Europe can be very proud," says Tim de Zeeuw, ESO's Director General. "We have built the most advanced ground-based optical observatory in the world, thanks to the combination of a long-term adequately-funded instrument and technology development plan with an approach where most of the instruments were built in collaboration with institutions in the member states, with in-kind contributions in labour compensated by guaranteed observing time." Sitting atop the 2600m high Paranal Mountain in the Chilean Atacama Desert, the VLT's design, suite of instruments, and operating principles set the standard for ground-based astronomy. It provides the European scientific community with a telescope array with collecting power significantly greater than any other facilities available at present, offering imaging and spectroscopy capabilities at visible and infrared wavelengths. Blue Flash at Paranal ESO PR Photo 16b/08 A Universe of Discoveries The first scientifically useful images, marking the official 'First Light' of the VLT, were obtained on the night of 25 to 26 May 1998, with a test camera attached to "Antu", Unit Telescope number 1. They were officially presented to the press on the 27 May, exactly ten years ago. Since then, all four Unit Telescopes and four Auxiliary Telescopes went into routine operations and the number of instruments has continued to grow, to fill all the possible positions in the telescopes where instruments can be attached. In 2007, about 500 peer-reviewed papers using data collected with VLT and VLTI instruments at Paranal were published in scientific journals. Since the start of science operations, in April 1999, the VLT has led to the publication of more than 2200 refereed papers, an average of about one paper published every single working day. "The combination of high operational efficiency, system reliability and uptime for scientific observations results in very high scientific productivity," says Andreas Kaufer, director of the La Silla Paranal Observatory. The VLT and VLTI have contributed to all areas of astronomy, including the nature of dark matter and dark energy; the extreme physics of gamma-ray bursts and supernovae; the formation, structure and evolution of galaxies; the properties of exoplanets, Solar System objects, star clusters and stellar populations, the interstellar and intergalactic medium, and of super-massive black holes in galactic nuclei, in particular the one in the Galactic Centre; and the formation of stars and planets. The stunning scientific success of the VLT has attracted new member states to ESO. In the past decade Portugal joined (in 2001, after a ten-year associate status), followed by the United Kingdom (2002), Finland (2004), Spain (2006) and the Czech Republic (2007). Austria also announced its intent to join later this year. Another measure of success is the number of observing proposals made every year for the use of the VLT, which is now above the 1900 mark. On average, the amount of time requested to use the VLT is 6 times higher than what is available. The VLT will continue to increase in power over the next decade. The first of the second-generation VLT instruments, X-Shooter, will come online this year, with KMOS, SPHERE and MUS

2008-05-01

408

Mobile machine hazardous working zone warning system  

DOEpatents

A warning system is provided for a mobile working machine to alert an individual of a potentially dangerous condition in the event the individual strays into a hazardous working zone of the machine. The warning system includes a transmitter mounted on the machine and operable to generate a uniform magnetic field projecting beyond an outer periphery of the machine in defining a hazardous working zone around the machine during operation. A receiver, carried by the individual and activated by the magnetic field, provides an alarm signal to alert the individual when he enters the hazardous working zone of the machine. 3 figs.

Schiffbauer, W.H.; Ganoe, C.W.

1999-08-17

409

Com1005 Machines and Intelligence  

E-print Network

Com1005 Machines and Intelligence Lecturers: Dr Amanda Sharkey, Professor Phil Green Monday, 1 October 2012 #12;What is Artificial Intelligence? Monday, 1 October 2012 #12;What is Artificial Intelligence? � "Artificial Intelligence (AI) is the study of intelligent behaviour (in humans, animals

Sharkey, Amanda

410

Analytical design of intelligent machines  

NASA Technical Reports Server (NTRS)

The problem of designing 'intelligent machines' to operate in uncertain environments with minimum supervision or interaction with a human operator is examined. The structure of an 'intelligent machine' is defined to be the structure of a Hierarchically Intelligent Control System, composed of three levels hierarchically ordered according to the principle of 'increasing precision with decreasing intelligence', namely: the organizational level, performing general information processing tasks in association with a long-term memory; the coordination level, dealing with specific information processing tasks with a short-term memory; and the control level, which performs the execution of various tasks through hardware using feedback control methods. The behavior of such a machine may be managed by controls with special considerations and its 'intelligence' is directly related to the derivation of a compatible measure that associates the intelligence of the higher levels with the concept of entropy, which is a sufficient analytic measure that unifies the treatment of all the levels of an 'intelligent machine' as the mathematical problem of finding the right sequence of internal decisions and controls for a system structured in the order of intelligence and inverse order of precision such that it minimizes its total entropy. A case study on the automatic maintenance of a nuclear plant illustrates the proposed approach.

Saridis, George N.; Valavanis, Kimon P.

1987-01-01

411

Computed Tomography Measuring Inside Machines  

NASA Technical Reports Server (NTRS)

Computed tomography applied to obtain approximate measurements of radial distances from centerline of turbopump to leading edges of diffuser vanes in turbopump. Use of computed tomography has significance beyond turbopump application: example of general concept of measuring internal dimensions of assembly of parts without having to perform time-consuming task of taking assembly apart and measuring internal parts on coordinate-measuring machine.

Wozniak, James F.; Scudder, Henry J.; Anders, Jeffrey E.

1995-01-01

412

Confldence Estimation for Machine Translation  

Microsoft Academic Search

We present a detailed study of confldence esti- mation for machine translation. Various meth- odsfordeterminingwhetherMToutputiscor- rect are investigated, for both whole sentences andwords. Sincethenotionofcorrectnessisnot intuitively clear in this context, difierent ways of deflning it are proposed. We present results ondatafromtheNIST2003Chinese-to-English MT evaluation.

John Blatz; Erin Fitzgerald; George Foster; Simona Gandrabur; Alex Kulesza; Alberto Sanchis; Nicola Ue-ng; RWTH Aachen

2003-01-01

413

Anisotropy of machine building materials  

NASA Technical Reports Server (NTRS)

The results of experimental studies of the anisotropy of elastic and strength characteristics of various structural materials, including pressure worked metals and alloys, laminated fiberglass plastics, and laminated wood plastics, are correlated and classified. Strength criteria under simple and complex stresses are considered as applied to anisotropic materials. Practical application to determining the strength of machine parts and structural materials is discussed.

Ashkenazi, Y. K.

1981-01-01

414

Simple Machines Curriculum. [Teachers' Manual.  

ERIC Educational Resources Information Center

This manual provides suggestions for investigating simple machines and the teaching of certain basic concepts which pertain to them. Many of the lessons are designed to be used with the commercially available LEGO kits, in an effort to teach concepts in a way in which students must translate pictures shown in two dimension into three-dimensional…

Anoka-Hennepin Independent School District No. 11, Coon Rapids, MN.

415

Electrochemical Machining Removes Deep Obstructions  

NASA Technical Reports Server (NTRS)

Electrochemical machining (ECM) is effective way of removing obstructing material between two deep holes supposed to intersect but do not because of misalignment of drilling tools. ECM makes it possible to rework costly castings otherwise scrapped. Method fast even for tough or hard alloys and complicated three-dimensional shapes.

Catania, Mark J.

1987-01-01

416

Machine Learning srihari Gaussian Distribution  

E-print Network

maximizes entropy (for given mean and variance) ­ Sum of set of random variables becomes increasingly) Proportional to Identity matrix (concentric circles) #12;6 Machine Learning srihari Joint, Marginal densities and the two marginals are also Gaussian · Given joint Gaussian N(x|µ,) with =-1 and x = [xa

417

Machining of aerospace titanium alloys  

Microsoft Academic Search

The performance of PCBN (AMBORITE*) and PCD (SYNDITE) has been compared with that of coated tungsten carbide tool currently being used to machine titanium aerospace alloy. Tests confirm that SYNDITE gives a better surface finish, longer tool life and more manageable swarf than other tools. In addition, the “quick-stop” technique establishes that, for all three cutting tools, a layer is

Farhad Nabhani

2001-01-01

418

Machinable dissolved metal oxide superconductors  

SciTech Connect

Powders of a metal oxide superconductor are mixed with sufficient amount (10--80 mol%) of In, Sn, and/or Al, to become nonbrittle, machinable. Preferred superconductors are YBa[sub 2]Cu[sub 3]O[sub 7[minus]x] and Bi-Sr-Ca-Cu-O compounds.

Chen, Chung-Hsuan.

1991-01-01

419

Training Invariant Support Vector Machines  

Microsoft Academic Search

Practical experience has shown that in order to obtain the best possible performance, prior knowledge about invariances of a classification problem at hand ought to be incorporated into the training procedure. We describe and review all known methods for doing so in support vector machines, provide experimental results, and discuss their respective merits. One of the significant new results reported

Dennis Decoste; Bernhard Schölkopf

2002-01-01

420

Electrochemical Machining Carves out Nanostructures  

NSDL National Science Digital Library

This news article from June 20, 2003 published by Great Britain's Institute of Physics, describes an electrochemical machining process that is being used to fabricate complex nanostructures. The work, produced by German and U.S. researchers, has the potential to compete with current lithographic processes.

Kalaugher, Liz

2008-04-23

421

Electrical Discharge Machining in Gas  

Microsoft Academic Search

In this paper, we show that electrical discharge machining (EDM) can be achieved in gas. With the help of a high-pressure gas flow supplied through a thin-walled pipe electrode, the molten workpiece material can be removed and flushed out of the working gap without being reattached to the electrode surfaces. The greatest advantage of this technique is that the tool

Masanori Kunieda; Masahiro Yoshida; Norio Taniguchi

1997-01-01

422

Basic Mathematics Machine Calculator Course.  

ERIC Educational Resources Information Center

This series of four text-workbooks was designed for tenth grade mathematics students who have exhibited lack of problem-solving skills. Electric desk calculators are to be used with the text. In the first five chapters of the series, students learn how to use the machine while reviewing basic operations with whole numbers, decimals, fractions, and…

Windsor Public Schools, CT.

423

Optical-Fiber-Welding Machine  

NASA Technical Reports Server (NTRS)

Technique yields joints with average transmissivity of 91.6 percent. Electric arc passed over butted fiber ends to melt them together. Maximum optical transmissivity of joint achieved with optimum choice of discharge current, translation speed, and axial compression of fibers. Practical welding machine enables delicate and tedious joining operation performed routinely.

Goss, W. C.; Mann, W. A.; Goldstein, R.

1985-01-01

424

Magnet arrays for synchronous machines  

Microsoft Academic Search

The authors demonstrate that the Halbach array is highly applicable for magnetic excitation in synchronous machines. To this end, they present the geometry of Halbach arrays in Cartesian, polar, and cylindrical coordinates. They also present the design of a Cartesian linear motor which has been optimized for use in conjunction with a class of high-precision magnetic suspension stages for photolithography.

David L. Trumper; Mark E. Williams; Tiep H. Nguyen

1993-01-01

425

Description of the Scenario Machine  

E-print Network

We present here an updated description of the "Scenario Machine" code. This tool is used to carry out a population synthesis of binary stars. Previous version of the description can be found at http://xray.sai.msu.ru/~mystery//articles/review/contents.html

V. M. Lipunov; K. A. Postnov; M. E. Prokhorov; A. I. Bogomazov

2007-04-11

426

Polar Warnings A Lifelike Machine  

E-print Network

1663 Polar Warnings A Lifelike Machine W88 Pit Certification The Business of Radioisotopes LOS of supercomputing. In addition to those signature Los Alamos facilities, materials science and actinide chemistry laboratories, gas guns, and firing sites are making vital contributions to Stockpile Stewardship. Manufacturing

427

Simulations of Quantum Turing Machines by Quantum Multi-Stack Machines  

E-print Network

As was well known, in classical computation, Turing machines, circuits, multi-stack machines, and multi-counter machines are equivalent, that is, they can simulate each other in polynomial time. In quantum computation, Yao [11] first proved that for any quantum Turing machines $M$, there exists quantum Boolean circuit $(n,t)$-simulating $M$, where $n$ denotes the length of input strings, and $t$ is the number of move steps before machine stopping. However, the simulations of quantum Turing machines by quantum multi-stack machines and quantum multi-counter machines have not been considered, and quantum multi-stack machines have not been established, either. Though quantum counter machines were dealt with by Kravtsev [6] and Yamasaki {\\it et al.} [10], in which the machines count with $0,\\pm 1$ only, we sense that it is difficult to simulate quantum Turing machines in terms of this fashion of quantum computing devices, and we therefore prove that the quantum multi-counter machines allowed to count with $0,\\pm 1,\\pm 2,...,\\pm n$ for some $n>1$ can efficiently simulate quantum Turing machines. Therefore, our mail goals are to establish quantum multi-stack machines and quantum multi-counter machines with counts $0,\\pm 1,\\pm 2,...,\\pm n$ and $n>1$, and particularly to simulate quantum Turing machines by these quantum computing devices.

Daowen Qiu

2005-01-30

428

Design of acoustical jackets for machines  

SciTech Connect

This work was carried out in cooperation with a Swedish machine manufacturer. The aim was to give design rules for acoustic jackets, an acoustic radiation shield mounted on a machine, close to its surface.

Boden, H.; Abom, M.

1982-01-01

429

Energy Conservation Within the Paper Machine Room  

E-print Network

their startling waste of energy, the corrective measures taken to reduce this waste of energy, the potential for waste recovery and equipment available for waste heat recovery. Areas under study include the press section, paper machine dryer section, and machine...

Walker, P. J.; Erskine, K. J.

1979-01-01

430

The timely self-portrait machine  

E-print Network

This thesis explores the philosophy which underlies the Timely Self-Portrait Machine. The cultural history of the machine, the phenomenon of Television, and the personal history of this project are discussed. Technical ...

Haun, Gregory Cosmo

1992-01-01

431

Using linguistic knowledge in statistical machine translation  

E-print Network

In this thesis, we present methods for using linguistically motivated information to enhance the performance of statistical machine translation (SMT). One of the advantages of the statistical approach to machine translation ...

Zbib, Rabih M. (Rabih Mohamed), 1974-

2010-01-01

432

Just the Facts: The Dialysis Machine  

MedlinePLUS

... bath and are drained away. The dialysis machine controls the flow of the blood and the bath. The dialysis ... d n e y, and monitors for blood flow, blood pressure, and air bubbles. The dialysate delivery system of the machine ...

433

Active Research Topics in Human Machine Interfaces.  

National Technical Information Service (NTIS)

This paper identifies active research topics concerning human machine interfaces for intelligent machine systems. The paper was compiled by performing a series of literature searches and organizing the information according to the author's interest in bet...

M. J. McDonald

2000-01-01

434

Auditing technology for electronic voting machines  

E-print Network

Direct Recording Electronic (DRE) voting machine security has been a significant topic of contention ever since Diebold voting machine code turned up on a public Internet site in 2003 and computer scientists at Johns Hopkins ...

Cohen, Sharon B

2005-01-01

435

Workshop on Fielded Applications of Machine Learing.  

National Technical Information Service (NTIS)

This report summarizes the talks presented at the Workshop on Fielded Applications of Machine Learning, and draws some initial conclusions about the state of machine learning and its potential for solving real-world problems.

P. Langley

1994-01-01

436

49 CFR 236.771 - Machine, control.  

Code of Federal Regulations, 2012 CFR

...Transportation 4 2012-10-01 2012-10-01 false Machine, control. 236.771 Section 236.771 Transportation...SYSTEMS, DEVICES, AND APPLIANCES Definitions § 236.771 Machine, control. An assemblage of manually operated devices...

2012-10-01

437

49 CFR 236.771 - Machine, control.  

Code of Federal Regulations, 2013 CFR

...Transportation 4 2013-10-01 2013-10-01 false Machine, control. 236.771 Section 236.771 Transportation...SYSTEMS, DEVICES, AND APPLIANCES Definitions § 236.771 Machine, control. An assemblage of manually operated devices...

2013-10-01

438

49 CFR 236.772 - Machine, interlocking.  

Code of Federal Regulations, 2012 CFR

...Transportation 4 2012-10-01 2012-10-01 false Machine, interlocking. 236.772 Section 236.772 Transportation...SYSTEMS, DEVICES, AND APPLIANCES Definitions § 236.772 Machine, interlocking. An assemblage of manually operated...

2012-10-01

439

49 CFR 236.771 - Machine, control.  

Code of Federal Regulations, 2011 CFR

...Transportation 4 2011-10-01 2011-10-01 false Machine, control. 236.771 Section 236.771 Transportation...SYSTEMS, DEVICES, AND APPLIANCES Definitions § 236.771 Machine, control. An assemblage of manually operated devices...

2011-10-01

440

49 CFR 236.772 - Machine, interlocking.  

Code of Federal Regulations, 2013 CFR

...Transportation 4 2013-10-01 2013-10-01 false Machine, interlocking. 236.772 Section 236.772 Transportation...SYSTEMS, DEVICES, AND APPLIANCES Definitions § 236.772 Machine, interlocking. An assemblage of manually operated...

2013-10-01

441

49 CFR 236.772 - Machine, interlocking.  

Code of Federal Regulations, 2011 CFR

...Transportation 4 2011-10-01 2011-10-01 false Machine, interlocking. 236.772 Section 236.772 Transportation...SYSTEMS, DEVICES, AND APPLIANCES Definitions § 236.772 Machine, interlocking. An assemblage of manually operated...

2011-10-01

442

Aqueous cutting fluid for machining fissionable materials  

DOEpatents

The present invention is directed to a cutting fluid for machining fissionable material. The cutting fluid is formed of glycol, water and boron compound in an adequate concentration for effective neutron attenuation so as to inhibit criticality incidents during machining.

Duerksen, Walter K. (Norris, TN); Googin, John M. (Oak Ridge, TN); Napier, Jr., Bradley (Powell, TN)

1984-01-01

443

Calculating Kinetics of a Student Designed Machine  

NSDL National Science Digital Library

This activity is a project-based inquiry where students design and create a machine to complete a task. Then students will be asked to calculate velocities, kinetic energy and potential energies of various parts of their machine.

444

On human machine cooperative learning control  

Microsoft Academic Search

Human-machine cooperation and learning control have essential connections. From a basic viewpoint, they all involve the work distribution among humans and machines. Studies on both of them cover many subjects: behavior model of human, human-machine interaction, intelligent control, etc. In this paper, we present a study combining human-machine cooperation and learning control, pay attention to a wide range of problems

Miaobo Dong; Zengqi Sun

2003-01-01

445

Three Dimensional Machine Vision Using Image Defocus  

E-print Network

Three Dimensional Machine Vision Using Image Defocus A Dissertation Presented by Tse-Chung Wei-Chung Wei 1994 #12; Abstract of the Dissertation Three Dimensional Machine Vision Using Image Defocus by Tse-dimensional machine vision. Fast new methods have been developed and implemented for recovering distance and focused

Subbarao, Murali "Rao"

446

Machine Vision: Proverbs, Opinions and Folklore  

E-print Network

Machine Vision: Proverbs, Opinions and Folklore Please cite: B.G. Batchelor and P.F. Whelan (1994), "Machine vision systems: Proverbs, principles, prejudices and priorities", Proceedings of the SPIE - The International Society for Optical Engineering, Vol. 2347 - Machine Vision Applications, Architectures

Whelan, Paul F.

447

Holding Irregularly Shaped Parts For Machining  

NASA Technical Reports Server (NTRS)

Part with complicated, irregular outside contours clamped for precise machining of internal passages with aid of simple method. Exterior of part cast in Rigidex, or equivalent epoxy. Forms wall to be clamped. Interior of part machined to finish of 125 microinches or finer. When machining finished, epoxy melted away by heating part to 200 degree F.

Hilton, Burt W.; Wilson, Rick R.

1988-01-01

448

Homopolar and bipolar hybrid excitation synchronous machines  

Microsoft Academic Search

This paper presents a description and operating principle of different hybrid excitation synchronous machines. Four prototype machines of different power rating (3 kW and 15 kW) have been studied. These machines combine two flux sources: permanent magnets, located in the rotor, and field coils, located in the stator. Thanks to this particular configuration the air gap flux can be easily

L. Vido; M. Gabsi; M. Lecrivain; Y. Amara; F. Chabot

2005-01-01

449

A Deep Learning Approach to Machine Transliteration  

Microsoft Academic Search

In this paper we present a novel translit- eration technique which is based on deep belief networks. Common approaches use finite state machines or other meth- ods similar to conventional machine trans- lation. Instead of using conventional NLP techniques, the approach presented here builds on deep belief networks, a tech- nique which was shown to work well for other machine

Thomas Deselaers; Oliver Bender; Hermann Ney

2009-01-01

450

Investigating Convergence of Restricted Boltzmann Machine Learning  

E-print Network

with missing data and are used to pretrain deep learning machines. RBMs learn a generative model of the dataInvestigating Convergence of Restricted Boltzmann Machine Learning Hannes Schulz Andreas M Machines are increasingly popular tools for unsuper- vised learning. They are very general, can cope

Behnke, Sven

451

Development of Hexapod Based Machine Tool  

Microsoft Academic Search

Machine tools with parallel structures have been the subject of discussion for a while now. Users are still largely unaware of the advantages offered by these new machine structures. This paper describes the design and variants of parallel-structured machine tools. Different design variants are compared with regard to the load of the structures and the singularity. Starting out from the

Hans-Jürgen Warnecke; Reimund Neugebauer; Frank Wieland

1998-01-01

452

Active Research Topics in Human Machine Interfaces  

Microsoft Academic Search

This paper identifies active research topics concerning human machine interfaces for intelligent machine systems. The paper was compiled by performing a series of literature searches and organizing the information according to the author's interest in better directing his own Human Machine Interface (HMI) research. Introductory literature from outside the HMI communities is also referenced to provide context.

Michael J. McDonald

2000-01-01

453

Abstract AndParallel Machines Nachum Dershowitz  

E-print Network

Abstract And­Parallel Machines Nachum Dershowitz University of Illinois Urbana, IL 61801 U are introduced. The first of them, the And­ Parallel Turing Machine, can be viewed as a generalization of the deterministic Turing machine in which the infinite tape is replaced by an infinite tree­like tape on which

Dershowitz, Nachum

454

Batch Scheduling with Deadlines on Parallel Machines  

E-print Network

Batch Scheduling with Deadlines on Parallel Machines Peter Brucker Mikhail Y. Kovalyov, Yakov M of scheduling G groups of jobs on m parallel machines is considered. Each group consists of several identical) and to schedule the batches on the machines. It is possible for different batches of the same group

Magdeburg, Universität

455

Environmental performance indicators of organic spreading machines  

E-print Network

1 Environmental performance indicators of organic spreading machines M. Rousselet1 *, J. C. Roux1 to French spreading machines. The task consists in defining relevant indicators specifically for spreaders indicator before and after improvement on the machine. Keywords: Environmental Performance Indicator

Paris-Sud XI, Université de

456

BUILDING INFINITE MACHINES E.B. Davies  

E-print Network

BUILDING INFINITE MACHINES E.B. Davies an infinite computing machine within a continuous Newtonian universe. The relevance of our construction* * to do it, [6, 9]. In section 4 we discuss why our machine is not in conflict with standard impos* *si

Davies, Brian

457

Technical Report No. 2006510 ACCELERATING MACHINES \\Lambda  

E-print Network

Technical Report No. 2006­510 ACCELERATING MACHINES \\Lambda Robert Fraser and Selim G. Akl School Abstract This paper presents an overview of accelerating machines. We begin by exploring the history of the accelerating machine model and the potential power that it provides. We look at some of the problems that could

Graham, Nick

458

Getting Started with Microsoft Azure Virtual Machines  

E-print Network

Getting Started with Microsoft Azure Virtual Machines Introduction You can use a Microsoft Azure Virtual Machine when you need a scalable, cloud-based server running a Windows or Linux operating system (IaaS), you can run a virtual machine on an ongoing basis, or you can stop and restart it later

Narasayya, Vivek

459

Biologically inspired mutual synchronization of manufacturing machines  

E-print Network

Biologically inspired mutual synchronization of manufacturing machines Erjen Lefeber,a,1 , Herman machine is developed. This control system is based on a synchronization mechanism of enzymes replacing of a single turnover cycle. In manufacturing, batch machines serve several jobs simultaneously, e.g., heat

Armbruster, Dieter

460

Nano-Machines Achieve Huge Mechanical Breakthrough  

E-print Network

NANO TECH Nano-Machines Achieve Huge Mechanical Breakthrough Dublin, Ireland (SPX) Sep 08, 2005 that use molecular 'nano'-machines of this kind to help perform physical tasks. Nano-machines could also owners set to return to battered Orleans l Six dead, two missing after heavy rains hit Page 1 of 3Nano

Leigh, David A.

461

Machine vision technology for agricultural applications  

Microsoft Academic Search

Current applications of machine vision in agriculture are briefly reviewed. The requirements and recent developments of hardware and software for machine vision systems are discussed, with emphases on multispectral and hyperspectral imaging for modern food inspection. Examples of applications for detection of disease, defects, and contamination on poultry carcasses and apples are also given. Future trends of machine vision technology

Yud-Ren Chen; Kuanglin Chao; Moon S. Kim

2002-01-01

462

Computational work and time on finite machines.  

NASA Technical Reports Server (NTRS)

Measures of the computational work and computational delay required by machines to compute functions are given. Exchange inequalities are developed for random access, tape, and drum machines to show that product inequalities between storage and time, number of drum tracks and time, number of bits in an address and time, etc., must be satisfied to compute finite functions on bounded machines.

Savage, J. E.

1972-01-01

463

A review of machine learning in scheduling  

Microsoft Academic Search

This paper has two primary purposes: to motivate the need for machine learning in scheduling systems and to survey work on machine learning in scheduling. In order to motivate the need for machine learning in scheduling, we briefly motivate the need for systems employing artificial intelligence methods for scheduling. This leads to a need for incorporating adaptive methods-learning

Haldun Aytug; Siddhartha Bhattacharyya; Gary J. Koehler; Jane L. Snowdon

1994-01-01

464

20 CFR 368.3 - Vending machines.  

Code of Federal Regulations, 2011 CFR

...2011-04-01 2011-04-01 false Vending machines. 368.3 Section 368.3 Employees...CIGARETTE SALES TO MINORS § 368.3 Vending machines. The sale of tobacco products in vending machines is prohibited in or around Federal...

2011-04-01

465

15 CFR 5.5 - Vending machines.  

Code of Federal Regulations, 2011 CFR

...2011-01-01 2011-01-01 false Vending machines. 5.5 Section 5.5 Commerce and...OPERATION OF VENDING STANDS § 5.5 Vending machines. (a) The income from any vending machines which are located within reasonable...

2011-01-01

466

20 CFR 368.3 - Vending machines.  

Code of Federal Regulations, 2012 CFR

...2012-04-01 2012-04-01 false Vending machines. 368.3 Section 368.3 Employees...CIGARETTE SALES TO MINORS § 368.3 Vending machines. The sale of tobacco products in vending machines is prohibited in or around Federal...

2012-04-01

467

Photogrammetry & Machine Vision 1. Image sensors  

E-print Network

Photogrammetry & Machine Vision 1. Image sensors (a) Fundamentals of image sensors (b) CCD image'Apuzzo Photogrammetry and Machine Vision - 3 Point cloud processing, surface generation, texturing (b) Camera, noise) 2N. D'Apuzzo Photogrammetry and Machine Vision - 3 Point cloud processing, surface generation

Giger, Christine

468

20 CFR 368.3 - Vending machines.  

...2014-04-01 2012-04-01 true Vending machines. 368.3 Section 368.3 Employees...CIGARETTE SALES TO MINORS § 368.3 Vending machines. The sale of tobacco products in vending machines is prohibited in or around Federal...

2014-04-01

469

15 CFR 5.5 - Vending machines.  

Code of Federal Regulations, 2013 CFR

...2013-01-01 2013-01-01 false Vending machines. 5.5 Section 5.5 Commerce and...OPERATION OF VENDING STANDS § 5.5 Vending machines. (a) The income from any vending machines which are located within reasonable...

2013-01-01

470

Photogrammetry & Machine Vision 1. Image sensors  

E-print Network

Photogrammetry & Machine Vision 1. Image sensors (a) Fundamentals of image sensors (b) CCD image. Remondino, N. D'Apuzzo Photogrammetry and Machine Vision ­ 2. Camera calibration and orientation (b) Camera and Machine Vision ­ 2. Camera calibration and orientation (b) Calibration methods (reference object, point

Giger, Christine

471

15 CFR 5.5 - Vending machines.  

Code of Federal Regulations, 2012 CFR

...2012-01-01 2012-01-01 false Vending machines. 5.5 Section 5.5 Commerce and...OPERATION OF VENDING STANDS § 5.5 Vending machines. (a) The income from any vending machines which are located within reasonable...

2012-01-01

472

Virtual Machine Monitors 36.1 Introduction  

E-print Network

36 Virtual Machine Monitors 36.1 Introduction Years ago, IBM sold mainframes to large organizations, and a problem arose: what if the organization wanted to run different operating systems on the machine? (some yet another level of indirection in the form of a virtual machine monitor, or VMM or just monitor

Sheridan, Jennifer

473

15 CFR 5.5 - Vending machines.  

...2014-01-01 2014-01-01 false Vending machines. 5.5 Section 5.5 Commerce and...OPERATION OF VENDING STANDS § 5.5 Vending machines. (a) The income from any vending machines which are located within reasonable...

2014-01-01

474

Photogrammetry & Machine Vision 1. Image sensors  

E-print Network

Photogrammetry & Machine Vision 1. Image sensors (a) Fundamentals of image sensors (b) CCD image. Remondino, N. D'Apuzzo Photogrammetry and Machine Vision ­ 1. Measurement in images (b) Camera calibration of Photogrammetry and Machine Vision Fully understand: 1. Image based 3D and 4D measurement 2. Image based 3D

Giger, Christine

475

20 CFR 368.3 - Vending machines.  

Code of Federal Regulations, 2013 CFR

...2013-04-01 2012-04-01 true Vending machines. 368.3 Section 368.3 Employees...CIGARETTE SALES TO MINORS § 368.3 Vending machines. The sale of tobacco products in vending machines is prohibited in or around Federal...

2013-04-01

476

Generation of Reaction Layers on Machined Surfaces  

Microsoft Academic Search

Machined surfaces are influenced by the generation of reaction layers resulting from the formulation of the metalworking fluid. Coolants reduce friction at the tool\\/surface interface and significantly influence the heat dissipation in machining operations and the generation of the surface layer. Nowadays, machining processes are evaluated with respect to the forces, grinding wheel wear, surface roughness, surface integrity, residual stresses,

E. Brinksmeier; A. Walter

2000-01-01

477

Cogging Torque Reduction in Permanent Magnet Machines  

Microsoft Academic Search

This paper examines two methods - magnet shifting and optimizing the magnet pole arc - for reducing cogging torque in permanent magnet machines. The methods were applied to existing machine designs and their performance was calculated using finite-element analysis (FEA). Prototypes of the machine designs were constructed and experimental results obtained. It is shown that the FEA predicted the cogging

Luke Dosiek; Pragasen Pillay

2007-01-01

478

Method and apparatus for monitoring machine performance  

DOEpatents

Machine operating conditions can be monitored by analyzing, in either the time or frequency domain, the spectral components of the motor current. Changes in the electric background noise, induced by mechanical variations in the machine, are correlated to changes in the operating parameters of the machine.

Smith, Stephen F. (Loudon, TN); Castleberry, Kimberly N. (Harriman, TN)

1996-01-01

479

Applications of Machine Learning in Information Retrieval.  

ERIC Educational Resources Information Center

Introduces the basic ideas that underpin applications of machine learning to information retrieval. Describes applications of machine learning to text categorization. Considers how machine learning can be applied to the query-formulation process. Examines methods of document filtering, where the user specifies a query that is to be applied to an…

Cunningham, Sally Jo; Witten, Ian H.; Littin, James

1999-01-01

480

Machine Learning for Signature Verification Harish Srinivasan  

E-print Network

Machine Learning for Signature Verification Harish Srinivasan , Sargur N. Srihari and Matthew J it can be viewed as one that involves machine learning from a population of signatures. There are two and performance phases is de- scribed. Keywords: machine learning, forensic signature examination, biometrics

481

E4 --Machine Learning Pedro Domingos  

E-print Network

E4 -- Machine Learning Pedro Domingos Department of Computer Science & Engineering University-543-2969 Abstract Machine learning's focus on ill-defined problems and highly flexible methods makes it ideally suited for KDD applications. Among the ideas machine learning contributes to KDD are the importance

Anderson, Richard

482

Ph.D. Program in Machine Learning  

E-print Network

Page 1 Ph.D. Program in Machine Learning Student Handbook Revised 7/20/12 #12;Page 2 Table Machine Learning Journal Club...................................................................................................17 #12;Page 3 Introduction The field of machine learning is concerned with the question of how

483

Accelerating materials property predictions using machine learning  

E-print Network

Accelerating materials property predictions using machine learning Ghanshyam Pilania1 , Chenchen of a diverse set of properties of material systems is possible by employing machine (or statistical) learning, falls under a radically different paradigm1,2 , namely, machine (or statistical) learning--a topic

Alpay, S. Pamir

484

Multiple coupled circuit modeling of induction machines  

Microsoft Academic Search

A multiple coupled circuit model is presented for simulation of induction machines with both arbitrary winding layout and\\/or unbalanced operating conditions. The model is derived by means of winding functions. No symmetry is assumed. The parameters of the model are calculated directly from the geometry and winding layout of the machine. The behavior of an induction machine during starting is

X. Luo; Yuefeng Liao; H. Toliyat; A. El-Antably; T.A. Lipo

1993-01-01

485

Multiple coupled circuit modeling of induction machines  

Microsoft Academic Search

A new multiple coupled circuit model is presented for simulation of induction machines with both arbitrary winding layout and\\/or unbalanced operating conditions. The model is derived by means of winding functions. No symmetry is assumed. The parameters of the model are calculated directly from the geometry and winding layout of the machine. The behavior of an induction machine during starting

Xiaogang Luo; Yuefeng Liao; H. A. Toliyat; A. El-Antably; T.A. Lipo

1995-01-01

486

Signal machines : localization of isolated accumulation Signal machines : localization of isolated  

E-print Network

Signal machines : localization of isolated accumulation Signal machines : localization of isolated'Orléans, Orléans, FRANCE 6 mars 2011 Journées Calculabilités Paris 1 / 39 #12;Signal machines : localization of isolated accumulation 1 Signal machines and isolated accumulations 2 Necessary conditions

Durand-Lose, Jérôme

487

TEHNOMUS -New Technologies and Products in Machine Manufacturing Technologies (1) CMM : coordinate measuring machine  

E-print Network

TEHNOMUS - New Technologies and Products in Machine Manufacturing Technologies (1) CMM : coordinate measuring machine - 1 - COMPARISON OF A MACHINE OF MEASUREMENT WITHOUT CONTACT AND A CMM(1) : OPTIMIZATION products, the process of measurement usually proceeds on a type of machine (for example CMM

Paris-Sud XI, Université de

488

09s1: COMP9417 Machine Learning and Data Mining Introduction to Machine Learning  

E-print Network

09s1: COMP9417 Machine Learning and Data Mining Introduction to Machine Learning March 12, 2008 Acknowledgement: Material derived from slides for the book Machine Learning, Tom Mitchell, McGraw-Hill, 1997 http to describe the motivation, scope and some application areas of machine learning. Following it you should

Bain, Mike

489

09s1: COMP9417 Machine Learning and Data Mining Machine Learning for Numeric  

E-print Network

09s1: COMP9417 Machine Learning and Data Mining Machine Learning for Numeric Prediction April 1, 2009 Acknowledgement: Material derived from slides for the book Machine Learning, Tom M. Mitchell, Mc by John Wiley & Sons, Inc. Aims This lecture will enable you to describe and reproduce machine learning

Bain, Mike

490

Page 1 May 2014 Machine Learning with Knowledge Graphs, ESWC 2014 Machine Learning with  

E-print Network

Page 1 May 2014 Machine Learning with Knowledge Graphs, ESWC 2014 Machine Learning with Knowledge Learning with Knowledge Graphs, ESWC 2014 Prelude My background is in Machine Learning and I got involved Thal, Austria #12;Page 3 May 2014 Machine Learning with Knowledge Graphs, ESWC 2014 Prelude My

Tresp, Volker

491

DEEP REINFORCEMENT LEARNING Machine Intelligence Lab @ The University of Tennessee  

E-print Network

DEEP REINFORCEMENT LEARNING Machine Intelligence Lab @ The University of Tennessee http Machine Intelligence Lab http://mil.engr.utk.edu Deep Machine Learning Biologically://mil.engr.utk.edu Deep Machine Learning Basic cortical circuit Massively parallel Discovers structure based

Wang, Xiaorui "Ray"

492

29 CFR 1910.212 - General requirements for all machines.  

Code of Federal Regulations, 2013 CFR

... false General requirements for all machines. 1910.212 Section 1910.212...AND HEALTH STANDARDS Machinery and Machine Guarding § 1910.212 General requirements for all machines. (a) Machine guarding...

2013-07-01

493

29 CFR 1910.212 - General requirements for all machines.  

Code of Federal Regulations, 2012 CFR

... false General requirements for all machines. 1910.212 Section 1910.212...AND HEALTH STANDARDS Machinery and Machine Guarding § 1910.212 General requirements for all machines. (a) Machine guarding...

2012-07-01

494

29 CFR 1910.212 - General requirements for all machines.  

... false General requirements for all machines. 1910.212 Section 1910.212...AND HEALTH STANDARDS Machinery and Machine Guarding § 1910.212 General requirements for all machines. (a) Machine guarding...

2014-07-01

495

29 CFR 1910.212 - General requirements for all machines.  

Code of Federal Regulations, 2011 CFR

... false General requirements for all machines. 1910.212 Section 1910.212...AND HEALTH STANDARDS Machinery and Machine Guarding § 1910.212 General requirements for all machines. (a) Machine guarding...

2011-07-01

496

Using machine learning techniques to interpret results from discrete event  

E-print Network

Using machine learning techniques to interpret results from discrete event simulation Dunja Mladeni machine learning techniques. The results of two simulators were processed as machine learning problems discovered. Key words: discrete event simulation, machine learning, artificial intelligence 1 Introduction

Mladenic, Dunja

497

Machine Learning Algorithms for Cancer Diagnosis Abraham Karplus  

E-print Network

Machine Learning Algorithms for Cancer Diagnosis Abraham Karplus Santa Cruz County Science Fair . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 Machine Learning 5 Testing Methods. The eventual goal of machine learning in cancer diagnosis is to have a trained machine learning algorithm that

Karplus, Kevin

498

Sequence-invariant state machines  

NASA Technical Reports Server (NTRS)

A synthesis method and an MOS VLSI architecture are presented to realize sequential circuits that have the ability to implement any state machine having N states and m inputs, regardless of the actual sequence specified in the flow table. The design method utilizes binary tree structured (BTS) logic to implement regular and dense circuits. The desired state sequence can be hardwired with power supply connections or can be dynamically reallocated if stored in a register. This allows programmable VLSI controllers to be designed with a compact size and performance approaching that of dedicated logic. Results of ICV implementations are reported and an example sequence-invariant state machine is contrasted with implementations based on traditional methods.

Whitaker, Sterling R.; Manjunath, Shamanna K.; Maki, Gary K.

1991-01-01

499

A neural support vector machine.  

PubMed

Support vector machines are state-of-the-art pattern recognition algorithms that are well founded in optimization and generalization theory but not obviously applicable to the brain. This paper presents Bio-SVM, a biologically feasible support vector machine. An unstable associative memory oscillates between support vectors and interacts with a feed-forward classification pathway. Kernel neurons blend support vectors and sensory input. Downstream temporal integration generates the classification. Instant learning of surprising events and off-line tuning of support vector weights trains the system. Emotion-based learning, forgetting trivia, sleep and brain oscillations are phenomena that agree with the Bio-SVM model. A mapping to the olfactory system is suggested. PMID:20092978

Jändel, Magnus

2010-06-01

500

Predicting phospholipidosis using machine learning.  

PubMed

Phospholipidosis is an adverse effect caused by numerous cationic amphiphilic drugs and can affect many cell types. It is characterized by the excess accumulation of phospholipids and is most reliably identified by electron microscopy of cells revealing the presence of lamellar inclusion bodies. The development of phospholipidosis can cause a delay in the drug development process, and the importance of computational approaches to the problem has been well documented. Previous work on predictive methods for phospholipidosis showed that state of the art machine learning methods produced the best results. Here we extend this work by looking at a larger data set mined from the literature. We find that circular fingerprints lead to better models than either E-Dragon descriptors or a combination of the two. We also observe very similar performance in general between Random Forest and Support Vector Machine models. PMID:20799726

Lowe, Robert; Glen, Robert C; Mitchell, John B O

2010-10-01