Sample records for heart-lung machine

  1. Perfusion of isolated organs and the first heart-lung machine.

    PubMed

    Zimmer, H G

    2001-09-01

    In 1885, Max von Frey (1852-1932), while working in Carl Ludwig's Physiological Institute in Leipzig, Germany, designed an apparatus that had criteria characteristic of a heart-lung machine. With this device, he perfused the entire lower extremity of dogs, and took measurements of oxygen consumption, and carbon dioxide and lactate production. In 1935, another type of perfusion apparatus was constructed by Charles A Lindbergh (1902-1973). This device was the result of cooperation with Alexis Carrel (1873-1944) who was a pioneer of experimental organ transplantation. Using Lindbergh's pulsating device, organs such as thyroid, ovary, suprarenal gland, spleen, heart and kidney from fowls and cats were perfused with an oxygenated medium, and were maintained under sterile conditions. Beginning in 1934, John H Gibbon (1903-1973) developed and tested a heart-lung machine to institute cardiopulmonary bypass in cats during experimental occlusion of the pulmonary artery. In 1953, he performed the first successful open-heart operation in a patient using a heart-lung machine. This included elements that were similar to those used by von Frey - ie, the oxygenator and the pumps for continuous circulation of blood. A comparison of the three experimental devices revealed the following: the application for experimental purposes preceded clinical use; the development shifted from Europe to the United States, and was achieved by people who were not specialists; and the intention to build such a device was first purely scientific interest, but later shifted to the care for and treatment of patients with heart and circulatory defects by open-heart surgery. PMID:11586387

  2. John Heysham Gibbon and the 60th anniversary of the first successful heart-lung machine: brief notes about the development of cardiac surgery in Europe and Slovakia.

    PubMed

    Silvay, G; Castillo, J G

    2013-01-01

    The development of the heart-lung machine and its first successful clinical application in 1953 was the culmination of Dr. Gibbon's lifetime research project. Despite many technical obstacles, financial problems, and discouragement from colleagues, his goal was achieved after twenty tedious years of tireless work. Posteriorly, his academic contribution established him as a leader and pioneer in the field of cardiac surgery. Parallel to his achievement and Dr. Kirklin's surgical experience, several authors around the world attempted open-heart surgery with the heart-lung machine, particularly in Europe. In Eastern Europe and particularly in the former Czechoslovakia, the lack of access to foreign medical literature forced a group of emerging young physicians from the Second Department of Surgery at Comenius University to furtively collect data on the topic. After building the Simkovic-Bolf heart-lung machine, the first successful open-heart surgery with the new device was performed only 5 years after Dr. Gibbons' experience (Tab. 1, Fig. 4, Ref. 22). PMID:23611045

  3. Heart-lung transplant - series (image)

    MedlinePLUS

    Heart-lung transplant operations have been performed since 1980 in the United States. The donated heart and lungs come from a human who has been declared brain-dead but remains on a life-support machine. A single recipient may receive one or both donor lungs. ...

  4. 76 FR 30371 - National Heart, Lung, and Blood Institute; Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-25

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Meetings...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  5. 76 FR 21387 - National Heart, Lung, and Blood Institute;

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-15

    ...Name of Committee: National Heart, Lung, and Blood Institute Special...Scientific Review/DERA, National Heart, Lung, and Blood Institute...Disorders Research; 93.837, Heart and Vascular Diseases Research; 93.838, Lung...

  6. National Heart, Lung, and Blood Institute

    NSDL National Science Digital Library

    The National Heart, Lung, and Blood Institute has crafted this excellent collection of materials for health care professionals. The materials are divided into a dozen sections, including Lung Information, Sleep Information, Interactive Tools and Resources, and Continuing Education Opportunities. The Interactive Tools and Resources area is a gem, as it includes applications for mobile devices such as a menu planner, a Body Mass Index (BMI) calculator, and an asthma mortality map. The Clinical Practice Guidelines area features reports crafted at professional development conferences that deal with cholesterol, obesity, and asthma. Additionally, the Continuing Education Opportunities area features guides to cultural competency and information about upcoming conferences and seminars.

  7. 70 FR 3715 - National Heart, Lung, and Blood Institute (NHLBI); Opportunity for a Cooperative Research and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2005-01-26

    ...National Institutes of Health National Heart, Lung, and Blood Institute (NHLBI...SUMMARY: The National Heart, Lung, and Blood Institute (NHLBI...Technology Transfer Specialist, National Heart, Lung, and Blood Institute...

  8. 61 FR 67842 - National Heart, Lung, and Blood Institute (NHLBI); Request for Capability Statements From Parties...

    Federal Register 2010, 2011, 2012, 2013, 2014

    1996-12-24

    ...DEPARTMENT OF HEALTH AND HUMAN SERVICES National Heart, Lung, and Blood Institute (NHLBI...SUMMARY: The National Heart, Lung, and Blood Institute (NHLBI...Technology Development Coordinator, National Heart, Lung, and Blood Institute,...

  9. 69 FR 1590 - National Heart, Lung, and Blood Institute (NHLBI): Opportunity for Cooperative Research and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2004-01-09

    ...National Institutes of Health National Heart, Lung, and Blood Institute (NHLBI...SUMMARY: The National Heart, Lung and Blood Institute (NHLBI) of...Technology Transfer and Development, National Heart, Lung, and Blood Institute,...

  10. 66 FR 31679 - National Heart, Lung, and Blood Institute; Proposed Collection; Comment Request The Framingham Study

    Federal Register 2010, 2011, 2012, 2013, 2014

    2001-06-12

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Proposed...Paperwork Reduction Act of 1995, the National Heart, Lung, and Blood Institute (NHLBI...Epidemiology and Clinical Applications, National Heart, Lung and Blood Institute, 6701...

  11. 62 FR 14157 - National Heart, Lung, and Blood Institute; Submission for OMB Review; Comment Request; The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    1997-03-25

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Submission...Paperwork Reduction Act of 1995, the National Heart, Lung, and Blood Institute (NHLBI...Project Clearance Liaison, National Heart, Lung, and Blood Institute, NIH,...

  12. 69 FR 32031 - National Heart, Lung, and Blood Institute (NHLBI); Opportunity for a Cooperative Research and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2004-06-08

    ...National Institutes of Health National Heart, Lung, and Blood Institute (NHLBI...Medicine Branch (P-CCMB) in National Heart, Lung, and Blood Institute (NHLBI...Technology Transfer Specialist, National Heart, Lung, and Blood Institute...

  13. 68 FR 68088 - National Heart, Lung, and Blood Institute (NHLBI): Opportunity for Cooperative Research and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2003-12-05

    ...National Institutes of Health National Heart, Lung, and Blood Institute (NHLBI...SUMMARY: The National Heart, Lung, and Blood Institute (NHLBI...Technology Transfer and Development, National Heart, Lung, and Blood Institute,...

  14. 65 FR 25338 - National Heart, Lung, and Blood Institute; Submission for OMB Review; Comment Request: The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2000-05-01

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Submission...Paperwork Reduction Act of 1995, the National Heart, Lung, and Blood Institute (NHLBI...Epidemiology and Clinical Applications, National Heart, Lung, and Blood Institute. [FR...

  15. 68 FR 48393 - National Heart, Lung, and Blood Institute: Licensing Opportunity and Cooperative Research and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2003-08-13

    ...National Institutes of Health National Heart, Lung, and Blood Institute: Licensing...Named ``SPOC'' Cells AGENCY: National Heart, Lung, and Blood Institute. ACTION...SUMMARY: The National Heart Lung and Blood Institute is seeking...

  16. 59 FR- National Heart, Lung and Blood Institute; Opportunity for a Cooperative Research and Development...

    Federal Register 2010, 2011, 2012, 2013, 2014

    1994-05-17

    ...National Institutes of Health National Heart, Lung and Blood Institute; Opportunity...SUMMARY: The National Heart, Lung and Blood Institute (NHLBI) of...National Institutes of Health, National Heart, Lung and Blood Institute, 9000...

  17. 65 FR 78177 - National Heart, Lung, and Blood Institute, Submission for OMB Review; Comment Request; The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2000-12-14

    ...National Institutes of Health National Heart, Lung, and Blood Institute, Submission...Paperwork Reduction Act of 1995, the National Heart, Lung, and Blood Institute (NHLBI...Epidemiology and Clinical Applications, National Heart, Lung, and Blood Institute. [FR...

  18. 69 FR 9830 - National Heart, Lung, and Blood Institute (NHLBI); Opportunity for a Cooperative Research and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2004-03-02

    ...National Institutes of Health National Heart, Lung, and Blood Institute (NHLBI...Medicine Branch (P-CCMB) in National Heart, Lung, and Blood Institute (NHLBI...Technology Transfer Specialist, National Heart, Lung, and Blood Institute...

  19. 61 FR 5564 - National Heart, Lung, and Blood Institute; Opportunity for a Cooperative Research and Development...

    Federal Register 2010, 2011, 2012, 2013, 2014

    1996-02-13

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Opportunity...SUMMARY: The National Heart, Lung, and Blood Institute (NHLBI...system. This project is with the National Heart, Lung, and Blood Institute,...

  20. 66 FR 20820 - National Heart, Lung, and Blood Institute; Proposed Collection; Comment Request; Multi-Ethnic...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2001-04-25

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Proposed...data collection projects, the National Heart, Lung, and Blood Institute (NHLBI...Epidemiology and Clinical Applications, National Heart, Lung, and Blood Institute. [FR...

  1. 65 FR 50999 - National Heart, Lung, and Blood Institute; Proposed Collection; Comment Request; The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2000-08-22

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Proposed...data collection projects, the National Heart, Lung, and Blood Institute (NHLBI...Epidemiology and Clinical Applications, National Heart, Lung, and Blood Institute. [FR...

  2. 78 FR 66031 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-04

    ...Institutes of Health National Heart, Lung, and Blood Institute...Committee: National Heart, Lung, and Blood Institute...Panel; Novel Tools to Prevent Sickle Cell Disease Complications. Date...Review/DERA, National Heart, Lung, and Blood...

  3. 77 FR 38849 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-29

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of Closed...Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  4. 77 FR 28612 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-15

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of Closed...privacy. Name of Committee National Heart, Lung, and Blood Institute Special Emphasis...Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  5. 77 FR 44640 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-30

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of Closed...Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  6. 76 FR 71580 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-18

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of Closed...Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  7. 77 FR 16246 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-20

    ...National Heart, Lung, and Blood Institute; Notice of Closed...National Heart, Lung, and Blood Institute Special Emphasis Panel; Omics and Genetic Analysis. Date: April 6, 2012...National Heart, Lung, and Blood Institute, 6701...

  8. 77 FR 6809 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-09

    ...National Heart, Lung, and Blood Institute; Notice of Closed...National Heart, Lung, and Blood Institute Special Emphasis Panel...for Lipoprotein Subfraction Analyses. Date: March 2, 2012. Time...National Heart, Lung, and Blood Institute, 6701 Rockledge...

  9. 78 FR 11657 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-19

    ...Institutes of Health National Heart, Lung, and Blood Institute...Name of Committee: National Heart, Lung, and Blood Institute...Emphasis Panel; Allogeneic Transplant Recipient Research Resource...Scientific Review/DERA, National Heart, Lung, and Blood...

  10. 78 FR 33428 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-04

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...personal privacy. Name of Committee: Heart, Lung, and Blood Initial Review Group...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  11. 78 FR 7792 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-04

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  12. 76 FR 12362 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-07

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  13. 75 FR 16152 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-31

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

  14. 77 FR 2738 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-19

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  15. 76 FR 58025 - National Heart, Lung and Blood Institute Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-19

    ...National Institutes of Health National Heart, Lung and Blood Institute Notice of Closed...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  16. 78 FR 29375 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-20

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  17. 76 FR 61722 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-05

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch, DERA, National Heart, Lung, and Blood Institute, 6701...

  18. 78 FR 30319 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-22

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  19. 77 FR 60705 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-04

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  20. 75 FR 80831 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-23

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  1. 76 FR 14674 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-17

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  2. 75 FR 50771 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-17

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

  3. 75 FR 9907 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-04

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

  4. 76 FR 63625 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-13

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  5. 75 FR 36427 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-25

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

  6. 76 FR 68200 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-03

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  7. 77 FR 76058 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-26

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  8. 75 FR 28260 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-20

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

  9. 77 FR 59935 - National Heart, Lung, And Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-01

    ...National Institutes of Health National Heart, Lung, And Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  10. 77 FR 3479 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-24

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  11. 76 FR 37134 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-24

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  12. 76 FR 11253 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-01

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  13. 77 FR 10538 - National Heart, Lung, and Blood Institute Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-22

    ...National Institutes of Health National Heart, Lung, and Blood Institute Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  14. 75 FR 52957 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-30

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

  15. 77 FR 33473 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-06

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  16. 78 FR 6122 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-29

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  17. 76 FR 47218 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-04

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  18. 75 FR 61507 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-05

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch, DERA, National Heart, Lung, and Blood Institute, 6701...

  19. 78 FR 67370 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-12

    ...SERVICES National Institutes of Health National Heart, Lung, and Blood Institute; Notice of Closed...invasion of personal privacy. Name of Committee: Heart, Lung, and Blood Initial Review Group; Heart, Lung, and Blood Program Project Review...

  20. 76 FR 57062 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-15

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  1. 77 FR 64818 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-23

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  2. 76 FR 12123 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-04

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

  3. 78 FR 12766 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-25

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National, Heart, Lung, and Blood Institute, 6701...

  4. 78 FR 63483 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-24

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  5. 76 FR 16631 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-24

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

  6. 78 FR 37233 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-20

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  7. 77 FR 6571 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-08

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  8. 77 FR 16843 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-22

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  9. 76 FR 12744 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-08

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

  10. 76 FR 70154 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-10

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  11. 78 FR 69431 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-19

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Office of Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

  12. 75 FR 4092 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-26

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

  13. 78 FR 69431 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-19

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  14. 76 FR 3641 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-20

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  15. 75 FR 31796 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-04

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

  16. 75 FR 42756 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-22

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

  17. 76 FR 29772 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-23

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

  18. 78 FR 35637 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-13

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  19. 75 FR 5090 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-01

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

  20. 75 FR 28032 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-19

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

  1. 77 FR 65568 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-29

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

  2. 73 FR 64340 - Memorandum of Understanding With the National Heart, Lung, and Blood Institute, a Part of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2008-10-29

    ...Memorandum of Understanding With the National Heart, Lung, and Blood Institute, a Part of...and Research (CBER) and the National Heart, Lung, and Blood Institute (NHLBI...Blood Diseases and Resources, National Heart, Lung, and Blood Institute MSC...

  3. Heart-lung transplantation: adult indications and outcomes

    PubMed Central

    Toyoda, Yasuhiro

    2014-01-01

    Combined heart-lung transplantation remains the only definitive therapy for patients who have both end-stage heart failure and end-stage lung failure. The most common indication is congenital heart disease (CHD) and the proportion is increasing for acquired heart disease concomitant with pulmonary hypertension and/or intrinsic lung diseases. Previously, idiopathic pulmonary hypertension was the most common indication. However, it has been shown that right ventricular failure can be reversed after double lung transplantation. Therefore, patients with idiopathic pulmonary arterial hypertension (IPAH) should not undergo combined heart-lung transplantation unless left ventricular dysfunction co-exists. The ISHLT registry data shows survival after heart-lung transplantation is improving, but still its survival rates are 71% at 3 months, 63% at 1 year, 44% at 5 years and 31% at 10 years. With appropriate patient selection and surgical expertise, these outcomes should improve further. PMID:25132981

  4. 64 FR 48661 - National Heart, Lung, and Blood Institute; Proposed Collection; Comment Request; Women's Health...

    Federal Register 2010, 2011, 2012, 2013, 2014

    1999-09-07

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Proposed...Office of the Director, the National Heart, Lung, and Blood Institute (NHLBI...postmenopausal women, namely, coronary heart disease, breast and colorectal...

  5. 63 FR 14722 - National Heart, Lung, and Blood Institute; Submission for OMB Review; Comment Request, the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    1998-03-26

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Submission...Paperwork Reduction Act of 1995, the National Heart, Lung, and Blood Institute, the National...hypothetical risk factors and coronary heart disease and stroke in people age 65...

  6. 65 FR 69031 - National Heart, Lung, and Blood Institute; Proposed Collection; Comment Request, The Jackson...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2000-11-15

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Proposed Collection; Comment Request, The Jackson Heart Study, Annual Follow-Up Component...data collection projects, the National Heart, Lung, and Blood Institute...

  7. 66 FR 14393 - National Heart, Lung and Blood Institute; Submission for OMB Review; Comment Request; The...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2001-03-12

    ...National Institutes of Health National Heart, Lung and Blood Institute; Submission...Paperwork Reduction Act of 1995, the National Heart, Lung, and Blood Institute (NHLBI...hypothetical risk factors and coronary heart disease [[Page 14394

  8. 63 FR 42864 - National Heart, Lung, and Blood Institute Proposed Collection; Comment Request Jackson Heart...

    Federal Register 2010, 2011, 2012, 2013, 2014

    1998-08-11

    ...National Institutes of Health National Heart, Lung, and Blood Institute Proposed Collection; Comment Request Jackson Heart Study Participant Recruitment Survey...data collection projects, the National Heart, Lung, and Blood Institute...

  9. 64 FR 63325 - National Heart, Lung, and Blood Institute Proposed Collection; Comment Request The Jackson Heart...

    Federal Register 2010, 2011, 2012, 2013, 2014

    1999-11-19

    ...National Institutes of Health National Heart, Lung, and Blood Institute Proposed Collection; Comment Request The Jackson Heart Study, Full Scale Exam I--Phase III...data collection projects, the National Heart, Lung, and Blood Institute...

  10. 65 FR 17513 - National Heart, Lung, and Blood Institute Submission for OMB Review; Comment Request Women's...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2000-04-03

    ...National Institutes of Health National Heart, Lung, and Blood Institute Submission...the Office of the Director, the National Heart, Lung, and Blood Institute (NHLBI...postmenopausal women, namely, coronary heart disease, breast and colorectal...

  11. 68 FR 14669 - National Heart, Lung, and Blood Institute; Submission for OMB Review; Comment Request, Women's...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2003-03-26

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Submission...the Office of the Director, the National Heart, Lung, and Blood Institute (NHLBI...postmenopausal women, namely, coronary heart disease, breast and colorectal...

  12. 67 FR 59294 - National Heart, Lung, and Blood Institute; Proposed Collection; Comment Request; Women's Health...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2002-09-20

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Proposed...Office of the Director, the National Heart, Lung, and Blood Institute (NHLBI...postmenopausal women, namely, coronary heart disease, breast and colorectal...

  13. 77 FR 67827 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-14

    ...Name of Committee: National Heart, Lung, and Blood Institute Special...Scientific Review/DERA, National Heart, Lung, and Blood Institute...Disorders Research; 93.837, Heart and Vascular Diseases Research; 93.838, Lung...

  14. 77 FR 1702 - National Heart, Lung, and Blood Institute; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-11

    ...Name of Committee: National Heart, Lung, and Blood Advisory Council...Research Activities, National Heart, Lung, and Blood Institute...Disorders Research; 93.837, Heart and Vascular Diseases Research; 93.838, Lung...

  15. 77 FR 43099 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-23

    ...Name of Committee: National Heart, Lung, and Blood Institute Special...Scientific Review/DERA, National Heart, Lung, and Blood Institute...Disorders Research; 93.837, Heart and Vascular Diseases Research; 93.838, Lung...

  16. 77 FR 59200 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-26

    ...Name of Committee: National Heart, Lung, and Blood Institute Special...Review Branch/DERA, National Heart, Lung, and Blood Institute...Disorders Research; 93.837, Heart and Vascular Diseases Research; 93.838, Lung...

  17. 77 FR 22580 - National Heart, Lung, and Blood Institute; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-16

    ...Name of Committee: National Heart, Lung, and Blood Advisory Council...Research Activities, National Heart, Lung, and Blood Institute...Disorders Research; 93.837, Heart and Vascular Diseases Research; 93.838, Lung...

  18. 75 FR 9912 - National Heart, Lung, and Blood Institute; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-04

    ...of Health National Heart, Lung, and Blood...of the Sickle Cell Disease Advisory Committee...Division of Blood Diseases and Resources, National Heart, Lung, and Blood...Research; 93.837, Heart and Vascular Diseases Research;...

  19. 77 FR 69870 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-21

    ...personal privacy. Name of Committee: Heart, Lung, and Blood Initial Review...Scientific Review/DERA, National Heart, Lung, and Blood Institute...Disorders Research; 93.837, Heart and Vascular Diseases Research; 93.838, Lung...

  20. 76 FR 70462 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-14

    ...and Blood Initial Review Group; Heart, Lung, and Blood Program Project...Scientific Review/DERA, National Heart, Lung, and Blood Institute...Disorders Research; 93.837, Heart and Vascular Diseases Research; 93.838, Lung...

  1. 76 FR 5596 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-01

    ...personal privacy. Name of Committee: Heart, Lung, and Blood Initial Review...Review Branch/DERA, National Heart, Lung, and Blood Institute...Disorders Research; 93.837, Heart and Vascular Diseases Research; 93.838, Lung...

  2. 78 FR 77477 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-23

    ...Name of Committee: National Heart, Lung, and Blood Institute Special...Scientific Review/DERA, National Heart, Lung, and Blood Institute...Disorders Research; 93.837, Heart and Vascular Diseases Research; 93.838, Lung...

  3. 75 FR 48979 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-12

    ...Name of Committee: National Heart, Lung, and Blood Institute Special...Review Branch/DERA, National Heart, Lung, and Blood Institute...Disorders Research; 93.837, Heart and Vascular Diseases Research; 93.838, Lung...

  4. 75 FR 29356 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-25

    ...and Blood Initial Review Group; Heart, Lung, and Blood Program Project...Review Branch/DERA, National Heart, Lung, and Blood Institute...Disorders Research; 93.837, Heart and Vascular Diseases Research; 93.838, Lung...

  5. 76 FR 28996 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-19

    ...and Blood Initial Review Group, Heart, Lung, and Blood Program Project...Scientific Review/DERA, National Heart, Lung, and Blood Institute...Disorders Research; 93.837, Heart and Vascular Diseases Research; 93.838, Lung...

  6. 77 FR 55853 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-11

    ...Name of Committee: National Heart, Lung, and Blood Institute Special...Scientific Review/DERA, National, Heart, Lung, and Blood Institute...Disorders Research; 93.837, Heart and Vascular Diseases Research; 93.838, Lung...

  7. 76 FR 40923 - National Heart, Lung, and Blood Institute Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-12

    ...National Institutes of Health National Heart, Lung, and Blood Institute Notice...Name of Committee: National Heart, Lung, and Blood Institute Special...Disorders Research; 93.837, Heart and Vascular Diseases Research; 93.838, Lung...

  8. 75 FR 66771 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-29

    ...Scientific Review, National Heart, Lung, and Blood Institute, 6701 Rockledge...Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Common Pathogenetic Mechanisms of Lung Cancer and COPD. Date: November 19,...

  9. 75 FR 71450 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-23

    ...Review Officer, Office of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701 Rockledge Drive, Room 7176, Bethesda, MD 20892-7924. 301-435-0310. whiterl@nhlbi.nih.gov. Name of Committee: National Heart, Lung,...

  10. 77 FR 71429 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-30

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel Jackson Heart Study Renewal. Date: December 17,...

  11. 75 FR 70273 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-17

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Antihypertensive and Lipid-Lowering to Prevent Heart Attack Trial. Date: December 1,...

  12. 77 FR 43343 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-24

    ...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel; Jackson Heart Study RFA Review. Date: August 15,...

  13. 76 FR 25701 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-05

    ...SERVICES National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...personal privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel, Heart Pumps for Clinical Trials for...

  14. 77 FR 13134 - National Heart, Lung, and Blood Institute: Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-05

    ...Committee: National Heart, Lung, and Blood Institute...Emphasis Panel; Sickle Cell Disease Program Project Grant...Review/DERA, National Heart, Lung, and Blood Institute...Research; 93.837, Heart and Vascular Diseases Research;...

  15. 75 FR 59276 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-27

    ...Committee: National Heart, Lung, and Blood Institute...Translational Programs in Lung Diseases. Date: October 14-15...Branch/DERA, National Heart, Lung, and Blood Institute...Research; 93.837, Heart and Vascular Diseases Research;...

  16. 77 FR 66855 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-07

    ...Committee: National Heart, Lung, and Blood Institute...Translational Programs in Lung Diseases. Date: November 27...Review/DERA, National Heart, Lung, and Blood Institute...Research; 93.837, Heart and Vascular Diseases Research;...

  17. 78 FR 57866 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-20

    ...Committee: National Heart, Lung, and Blood...Myeloid Dysplasia Diseases. Date: October...Committee: National Heart, Lung, and Blood...Myeloid Dysplasia Diseases. Date: October...Research; 93.837, Heart and Vascular Diseases Research;...

  18. 76 FR 58285 - National Heart, Lung, and Blood Institute Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-20

    ...Committee: National Heart, Lung, and Blood...in Cardiovascular Disease. Date: October...Committee: National Heart, Lung, and Blood...Trials for Lung Diseases (UM1). Date...Research; 93.837, Heart and Vascular Diseases Research;...

  19. 78 FR 12767 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-25

    ...Committee: National Heart, Lung, and Blood Institute...Translational Programs in Lung Diseases. Date: March 13, 2013...Review/DERA, National Heart, Lung, and Blood Institute...Research; 93.837, Heart and Vascular Diseases Research;...

  20. 77 FR 5261 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-02

    ...Review/DERA, National Heart, Lung, and Blood Institute...Committee: National Heart, Lung, and Blood Institute...Haptoglobin for Sickle Cell Disease. Date: February 24...Research; 93.837, Heart and Vascular Diseases Research;...

  1. 78 FR 31952 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-28

    ...Committee: National Heart, Lung, and Blood Institute...Research Projects in Blood Diseases. Date: June 18, 2013...Branch/DERA National Heart, Lung, and Blood Institute...Research; 93.837, Heart and Vascular Diseases Research;...

  2. 77 FR 14533 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-12

    ...Committee: National Heart, Lung, and Blood Institute...Calcific Aortic Valve Disease. Date: April 4, 2012...Review/DERA, National Heart, Lung, and Blood Institute...Research; 93.837, Heart and Vascular Diseases Research;...

  3. Temporary ECMO support following lung and heart-lung transplantation

    Microsoft Academic Search

    Duc Q Nguyen; David M Kulick; R. M Bolman; Jordan M Dunitz; Marshall I Hertz; Soon J Park

    2000-01-01

    Following lung and heart-lung transplantation, pulmonary graft failure unresponsive to aggressive conventional therapy may be fatal. Fourteen transplant recipients were placed on extracorporeal membrane oxygenation (ECMO) for pulmonary graft dysfunction. Nine patients had early (? 24 hours) graft failure while 5 had late (> 7 days) failure. Seven (78%) patients in the early group were weaned off ECMO and 5

  4. Cardiopulmonary bypass: development of John Gibbon's heart-lung machine

    PubMed Central

    Passaroni, Andréia Cristina; Silva, Marcos Augusto de Moraes; Yoshida, Winston Bonetti

    2015-01-01

    Objective To provide a brief review of the development of cardiopulmonary bypass. Methods A review of the literature on the development of extracorporeal circulation techniques, their essential role in cardiovascular surgery, and the complications associated with their use, including hemolysis and inflammation. Results The advancement of extracorporeal circulation techniques has played an essential role in minimizing the complications of cardiopulmonary bypass, which can range from various degrees of tissue injury to multiple organ dysfunction syndrome. Investigators have long researched the ways in which cardiopulmonary bypass may insult the human body. Potential solutions arose and laid the groundwork for development of safer postoperative care strategies. Conclusion Steady progress has been made in cardiopulmonary bypass in the decades since it was first conceived of by Gibbon. Despite the constant evolution of cardiopulmonary bypass techniques and attempts to minimize their complications, it is still essential that clinicians respect the particularities of each patient's physiological function.

  5. Heart-lung, single and double lung transplantation

    Microsoft Academic Search

    S. W. H. Kendall; F. C. Ciulli; C. M. J. Dennis; P. A. Mullins; J. Parameshwar; J. P. McGoldrick; S. R. Large; F. C. Wells; J. Wallwork

    1994-01-01

    Background: Lung and heart-lung transplantation (HLT) are now established treatments for end-stage pulmonary vascular disease and chronic\\u000a lung disease. The biggest limitation to lung transplantation (LT) is the limitation of suitable donor organs and will probably\\u000a never meet the demand required.\\u000a \\u000a \\u000a Methods: A review of publications from different centres shows that recipient selection, surgical techniques and post-operative care\\u000a are becoming

  6. 59 FR- National Heart, Lung, and Blood Institute Grants for Prevention and Control Projects

    Federal Register 2010, 2011, 2012, 2013, 2014

    1994-11-17

    ...42 CFR Part 52e RIN 0905-AE25 National Heart, Lung, and Blood Institute Grants for...governing grants awarded by the National Heart, Lung, and Blood Institute (NHLBI...those segments of the public afflicted by heart, blood vessel, lung, and blood...

  7. 69 FR 5553 - National Heart, Lung, and Blood Institute Proposed Collection; Comment Request Exam 2-The Jackson...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2004-02-05

    ...National Institutes of Health National Heart, Lung, and Blood Institute Proposed Collection...Comment Request Exam 2--The Jackson Heart Study, Annual Follow-Up Component Summary...Paperwork Reduction Act of 1995, the National Heart, Lung, and Blood Institute...

  8. 68 FR 53177 - National Heart, Lung, and Blood Institute Proposed Collection; Comment Request Exam 2-The Jackson...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2003-09-09

    ...National Institutes of Health National Heart, Lung, and Blood Institute Proposed Collection...Comment Request Exam 2--The Jackson Heart Study, Annual Follow-Up Component SUMMARY...data collection projects, the National Heart, Lung, and Blood Institute...

  9. 75 FR 18849 - Food and Drug Administration/National Heart Lung and Blood Institute/National Science Foundation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-13

    ...FDA-2010-N-0001] Food and Drug Administration/National Heart Lung and Blood Institute/National Science Foundation Workshop...Session.'' FDA is cosponsoring the workshop with the National Heart Lung and Blood Institute of the National Institutes of...

  10. National Heart Lung and Blood Institute: Information for Health Professionals

    NSDL National Science Digital Library

    Health care professionals and educators will be delighted to learn about this site, provided that they haven't heard about it already. Created by the National Heart Lung and Blood Institute, this site brings together a number of interactive tools and online resources that will be of great use to those in these fields. The site includes such materials as asthma mortality maps of the United States, BMI calculators, and a variety of other health assessment tools, such as menu planners and a ten-year heart attack risk calculator. Additionally, the site contains slide shows and downloadable slide sets on asthma, cholesterol, and high blood pressure that can be used by health care educators.

  11. Regional pulmonary perfusion following human heart-lung transplantation

    SciTech Connect

    Lisbona, R.; Hakim, T.S.; Dean, G.W.; Langleben, D.; Guerraty, A.; Levy, R.D. (Royal Victoria Hospital, Montreal, Quebec (Canada))

    1989-08-01

    Ventilation and perfusion scans were obtained in six subjects who had undergone heart-lung transplantation with consequent denervation of the cardiopulmonary axis. Two of the subjects had developed obliterative bronchiolitis, which is believed to be a form of chronic rejection. Their pulmonary function tests demonstrated airflow obstruction and their scintigraphic studies were abnormal. In the remaining four subjects without obstructive airways disease, ventilation and planar perfusion scans were normal. Single photon emission computed tomography imaging of pulmonary perfusion in these patients revealed a layered distribution of blood flow indistinguishable from that of normal individuals. It is concluded that neurogenic mechanisms have little influence on the pattern of local pulmonary blood flow at rest.

  12. 75 FR 33626 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-14

    ...Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel Comparative Effectiveness Research in Clinical Hypertension Management. Date: June 24, 2010. Time: 12 p.m. to 3 p.m. Agenda: To review and evaluate grant...

  13. Lung Graft Dysfunction in the Early Postoperative Period After Lung and Heart Lung Transplantation

    Microsoft Academic Search

    R. Vicente Guillén; F. Ramos Briones; P. Morales Mar??n; A. Solé Jover; J. M. Loro Represa; A. Pastor Colom

    2005-01-01

    BackgroundWe present a retrospective study of 9 years of experience in the management of graft dysfunction in the early postoperative period after lung transplantation (LT) and heart lung transplantation (HLT).

  14. 77 FR 54922 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-06

    ...Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel; Program Project Grant in Hypoxia and Sleep Medicine. Date: September 28, 2012. Time: 8 a.m. to 12 p.m. Agenda: To review and evaluate grant...

  15. 76 FR 1186 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-07

    ...Review Officer, Office of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701 Rockledge Drive, Room 7176, Bethesda, MD 20892-7924, 301-435-0310. whiterl@nhlbi.nih.gov. (Catalogue of Federal Domestic Assistance...

  16. 77 FR 50517 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-21

    ...Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel; Maximizing Scientific Return on the Women's Health Initiative Biological Resource. Date: September 7, 2012. Time: 8:30 a.m. to 5:00 p.m. Agenda: To...

  17. 77 FR 16844 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-22

    ...Name of Committee: National Heart, Lung, and Blood Institute...Resource-related Application in Congenital Heart Diseases (R24). Date: April 17...Disorders Research; 93.837, Heart and Vascular Diseases Research; 93.838, Lung...

  18. 78 FR 48880 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-12

    ...Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel; Randomized Trial on Medication Adherence Intervention in Primary Care. Date: September 9, 2013. Time: 10:00 a.m. to 11:30 a.m. Agenda:...

  19. 76 FR 78285 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-16

    ...Heart, Lung, and Blood Institute Special Emphasis Panel, Program Project Grant Review in Vascular Medicine and Atherosclerosis. Date: January 10, 2012. Time: 1 p.m. to 4 p.m. Agenda: To review and evaluate grant...

  20. The incidence of renal failure in one hundred consecutive heart-lung transplant recipients

    Microsoft Academic Search

    James M. Pattison; Jeffrey Petersen; Paul Kuo; Vincent Valantine; Robert C. Robbins; James Theodore

    1995-01-01

    Between March 1981 and November 1992, 100 heart-lung transplantations were performed at our institution. We report on the renal function in the 67 patients who survived a minimum of 6 months posttransplantation, and who were aged more than 10 years at the time of transplant. Renal function was determined by serial measurement of serum creatinine. Mean serum creatinine increased from

  1. 76 FR 61720 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-05

    ...National Heart, Lung, and Blood Institute Special Emphasis Panel, Genomic Research in AAT-Deficiency and Sarcoidosis--Genomics and Informatics Center. Date: October 27, 2011. Time: 9:30 a.m. to 1 p.m. Agenda: To review and evaluate...

  2. The Role of School Health Education in Preventing Heart, Lung, and Blood Diseases.

    ERIC Educational Resources Information Center

    Kolbe, Lloyd J.; Newman, Ian M.

    1984-01-01

    This article reviews the scope and dynamics of heart, lung, and blood diseases and explains the need for research on primary prevention programs for children. Suggestions for school health education programs that contribute to disease prevention are delineated. (Author/DF)

  3. 77 FR 48526 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-14

    ...invasion of personal privacy. Name of Committee: National Heart, Lung, and Blood Institute, Special Emphasis Panel, Biostatistics Training Summer Program (T15). Date: September 6, 2012. Time: 8:00 a.m. to 5:00 p.m. Agenda: To...

  4. 68 FR 24489 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2003-05-07

    ...National Heart, Lung, and Blood Institute Special Emphasis Panel, Role of Sleep and Sleep-Disordered Breathing in Metabolic Syndrome. Date: June 24, 2003. Time: 8 a.m. to 5p.m. Agenda: To review and evaluate grant applications....

  5. 78 FR 63995 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-25

    ...invasion of personal privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel Intermittent Hypoxia Review. Date: November 5, 2013. Time: 12:00 p.m. to 5:00 p.m. Agenda: To review and evaluate grant...

  6. 78 FR 20670 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-05

    ...unwarranted invasion of personal privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel; Hypoxia and Respiration. Date: April 30, 2013. Time: 9:00 a.m. to 11:30 a.m. Agenda: To review and evaluate grant...

  7. ABNORMAL FUNCTIONAL DEVELOPMENT OF THE HEART, LUNGS, AND KIDNEYS: APPROACHES TO FUNCTIONAL TERATOLOGY

    EPA Science Inventory

    Presentations given at the Conference on Abnormal Functional Development of the Heart, Lungs, and Kidneys are documented in this publication. The meeting was sponsored by the U.S. Environmental Protection Agency and was held in Asheville, NC, May 11-13, 1983. In an attempt to car...

  8. 75 FR 21644 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-26

    ...yoh@mail.nih.gov. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel, Women's Health Initiative Field. Date: May 19, 2010. Time: 8 a.m. to 3 p.m. Agenda: To review and evaluate contract...

  9. Conformal piezoelectric energy harvesting and storage from motions of the heart, lung, and diaphragm

    E-print Network

    Rogers, John A.

    Conformal piezoelectric energy harvesting and storage from motions of the heart, lung collection of such energy-harvesting elements with rectifiers and microbatteries provides an entire flexible, or to extend their lifetimes in a significant way. Investigations into energy-harvesting strategies to replace

  10. 78 FR 60299 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-01

    ...Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel, NHLBI Program Project for Atherosclerosis. Date: October 29, 2013. Time: 8:00 a.m. to 1:00 p.m. Agenda: To review and evaluate grant...

  11. Morphological changes in the heart, lungs and brain after experimental cavopulmonary anastomosis

    Microsoft Academic Search

    T. M. Darbinyan; L. D. Krymskii

    1959-01-01

    The authors studied the morphological changes occurring in the heart, lungs and brain after placing the cavopulmonary anastomosis. Experiments performed on 21 dogs established that prolonged occlusion of the superior vena cava during placing the cavopulmonary anastomosis may cause the development of diapedetic hemorrhages in the brain substance. The placing of cavopulmonary anastomosis may cause the development of fibrinous pleurisy

  12. Dr. Sonia Skarlatos and the National Heart, Lung, and Blood Institute Translational Research and Resource Programs

    PubMed Central

    2013-01-01

    Abstract Sonia I. Skarlatos, PhD (September 28, 1953–August 6, 2013), was the deputy director of the Division of Cardiovascular Sciences at the National Heart, Lung, and Blood Institute (NHLBI). This article reviews her work in establishing, leading, or facilitating extramural translational research programs supported by the NHLBI, specifically focusing on her work as a consistent advocate for the advancement of gene and cell therapies. PMID:24164237

  13. The role of cardiopulmonary exercise testing in lung and heart-lung transplantation.

    PubMed

    Howard, D K; Iademarco, E J; Trulock, E P

    1994-06-01

    Cardiopulmonary exercise testing in recipients of lung and heart-lung transplants demonstrates significant restoration of exercise tolerance to individuals severely disabled by their underlying cardiopulmonary disease. Recipients can perform moderate levels of activity compatible with a normal lifestyle. Considerable exercise limitation, however, remains in most recipients as measured by maximum oxygen uptake and work rate, despite substantial improvement and often normalization in resting cardiopulmonary function. The amount of exercise limitation observed in recipients of single-lung, bilateral-lung, and heart-lung transplants is interestingly similar, and the pattern of limitation is somewhat stereotyped. Ventilatory abnormalities are never limiting. Gas exchange abnormalities are sometimes seen (especially in single-lung transplant recipients) but generally are not limiting. Cardiac dysfunction is sometimes seen (particularly in heart-lung transplant recipients) but also does not appear to be limiting. Peripheral factors limiting exercise (which may include abnormalities in the peripheral circulation and peripheral neuromuscular structure and function) are almost universally seen and are probably the primary determinant of exercise limitation in these patients. At present, the relative contributions of various peripheral factors to exercise limitation are unclear. Further study may help elucidate these issues. PMID:8088101

  14. Heart-lung transplantation in situs inversus. A case report in a patient with Kartagener's syndrome.

    PubMed

    Miralles, A; Muneretto, C; Gandjbakhch, I; Lecompte, Y; Pavie, A; Rabago, G; Bracamonte, L; Desruennes, M; Cabrol, A; Cabrol, C

    1992-02-01

    After a long history of recurrent chronic pulmonary infections in a 25-year-old woman with Kartagener's syndrome, a heart-lung transplantation was performed. A modified surgical procedure was needed to perform transplantation because of the presence of a situs inversus, which is usually associated with bronchiectasis and sinusitis in this congenital syndrome. A large single atrium was created with both the right and left recipient atria used to facilitate anastomosis with the donor's right atrium. The patient was discharged after resolution of early ventilatory complications and is in good condition 8 months after transplantation. PMID:1735997

  15. Elucidating Nature’s Solutions to Heart, Lung, and Blood Diseases and Sleep Disorders

    PubMed Central

    Carey, Hannah V.; Martin, Sandra L.; Horwitz, Barbara A.; Yan, Lin; Bailey, Shannon M.; Podrabsky, Jason; Storz, Jay F.; Ortiz, Rudy M.; Wong, Renee P.; Lathrop, David A.

    2012-01-01

    Evolution has provided a number of animal species with extraordinary phenotypes. Several of these phenotypes allow species to survive and thrive in environmental conditions that mimic disease states in humans. The study of evolved mechanisms that responsible for these phenotypes may provide insights into the basis of human disease and guide the design of new therapeutic approaches. Examples include species that tolerate acute or chronic hypoxemia like deep-diving mammals and high-altitude inhabitants, as well as those that hibernate and interrupt their development when exposed to adverse environments. The evolved traits exhibited by these animal species involve modifications of common biological pathways that affect metabolic regulation, organ function, antioxidant defenses, and oxygen transport. In 2006, the National Heart, Lung, and Blood Institute (NHLBI) released a funding opportunity announcement to support studies that were designed to elucidate the natural molecular and cellular mechanisms of adaptation in species that tolerate extreme environmental conditions. The rationale for this funding opportunity is detailed in this Special Article, and the specific evolved mechanisms examined in the supported research are described. Also highlighted are past medical advances achieved through the study of animal species that have evolved extraordinary phenotypes as well as the expectations for new understanding of nature’s solutions to heart, lung, blood, and sleep disorders through future research in this area. PMID:22461362

  16. Super liquid-repellent gas membranes for carbon dioxide capture and heart–lung machines

    PubMed Central

    Paven, Maxime; Papadopoulos, Periklis; Schöttler, Susanne; Deng, Xu; Mailänder, Volker; Vollmer, Doris; Butt, Hans-Jürgen

    2013-01-01

    In a gas membrane, gas is transferred between a liquid and a gas through a microporous membrane. The main challenge is to achieve a high gas transfer while preventing wetting and clogging. With respect to the oxygenation of blood, haemocompatibility is also required. Here we coat macroporous meshes with a superamphiphobic—or liquid repellent—layer to meet this challenge. The superamphiphobic layer consists of a fractal-like network of fluorinated silicon oxide nanospheres; gas trapped between the nanospheres keeps the liquid from contacting the wall of the membrane. We demonstrate the capabilities of the membrane by capturing carbon dioxide gas into a basic aqueous solution and in addition use it to oxygenate blood. Usually, blood tends to clog membranes because of the abundance of blood cells, platelets, proteins and lipids. We show that human blood stored in a superamphiphobic well for 24?h can be poured off without leaving cells or adsorbed protein behind. PMID:24065073

  17. Assessment and treatment of depression in patients with cardiovascular disease: National heart, lung, and blood institute working group report

    Microsoft Academic Search

    Karina W. Davidson; David J. Kupfer; J. Thomas Bigger; Robert M. Califf; Robert M. Carney; James C. Coyne; Susan M. Czajkowski; Ellen Frank; Nancy Frasure-Smith; Kenneth E. Freedland; Erika S. Froelicher; Alexander H. Glassman; Wayne J. Katon; Peter G. Kaufmann; Ronald C. Kessler; Helena C. Kraemer; K. Ranga R. Krishnan; François Lespérance; Nina Rieckmann; David S. Sheps; Jerry M. Suls

    2006-01-01

    Objective: The National Heart, Lung, and Blood Institute convened an interdisciplinary working group of experts to develop recommendations for the assessment and treatment of depression in patients with coronary heart disease (CHD). Method: Consensus of experts. Results: Our current recommendations are that the Beck Depression Inventory-I be employed for epidemiological studies of depression and CHD, that the Patient Health Questionnaire

  18. The Relationship between National Heart, Lung, and Blood Institute Weight Guidelines and Concurrent Medical Costs in a Manufacturing Population.

    ERIC Educational Resources Information Center

    Wang, Feifei; Schultz, Alyssa B.; Musich, Shirley; McDonald, Tim; Hirschland, David; Edington, Dee W.

    2003-01-01

    Explored the relationship between the 1998 National Heart, Lung, and Blood Institute (NHLBI) weight guidelines and concurrent medical costs among 177,971 employees, retirees, and adult dependents from a nationwide manufacturing corporation. Results indicated that the six weight groups defined by the NHLBI guidelines were consistent with concurrent…

  19. Conformal piezoelectric energy harvesting and storage from motions of the heart, lung, and diaphragm

    PubMed Central

    Dagdeviren, Canan; Yang, Byung Duk; Su, Yewang; Tran, Phat L.; Joe, Pauline; Anderson, Eric; Xia, Jing; Doraiswamy, Vijay; Dehdashti, Behrooz; Feng, Xue; Lu, Bingwei; Poston, Robert; Khalpey, Zain; Ghaffari, Roozbeh; Huang, Yonggang; Slepian, Marvin J.; Rogers, John A.

    2014-01-01

    Here, we report advanced materials and devices that enable high-efficiency mechanical-to-electrical energy conversion from the natural contractile and relaxation motions of the heart, lung, and diaphragm, demonstrated in several different animal models, each of which has organs with sizes that approach human scales. A cointegrated collection of such energy-harvesting elements with rectifiers and microbatteries provides an entire flexible system, capable of viable integration with the beating heart via medical sutures and operation with efficiencies of ?2%. Additional experiments, computational models, and results in multilayer configurations capture the key behaviors, illuminate essential design aspects, and offer sufficient power outputs for operation of pacemakers, with or without battery assist. PMID:24449853

  20. Optogenetic sensors and effectors: CHROMus—the Cornell Heart Lung Blood Institute Resource for Optogenetic Mouse Signaling

    PubMed Central

    Shui, Bo; Lee, Jane C.; Reining, Shaun; Lee, Frank K.; Kotlikoff, Michael I.

    2014-01-01

    Significant progress has been made in the last decade in the development of optogenetic effectors and sensors that can be deployed to understand complex biological signaling in mammals at a molecular level, without disrupting the distributed, lineage specific signaling circuits that comprise nuanced physiological responses. A major barrier to the widespread exploitation of these imaging tools, however, is the lack of readily available genetic reagents that can be easily combined to probe complex biological processes. Ideally, one could envision purpose–produced mouse lines expressing optically compatible sensors and effectors, sensor pairs in distinct lineages, or sensor pairs in discrete subcellular compartments, such that they could be crossed to enable in vivo imaging studies of unprecedented scientific power. Such lines could also be combined with mice to determine the alteration in signaling accompanying targeted gene deletion or addition. In order to address this lack, the National Heart Lung and Blood Institute has recently funded an optogenetic resource designed to create optically compatible, combinatorial mouse lines that will advance NHLBI research. Here we review recent advances in optogenetic sensor and effectors and describe the rationale and goals for the establishment of the Cornell/National Heart Lung Blood Resource for Optogenetic Mouse Signaling (CHROMus). PMID:25414670

  1. Strategic transformation of population studies: recommendations of the working group on epidemiology and population sciences from the National Heart, Lung, and Blood Advisory Council and Board of External Experts.

    PubMed

    Roger, Véronique L; Boerwinkle, Eric; Crapo, James D; Douglas, Pamela S; Epstein, Jonathan A; Granger, Christopher B; Greenland, Philip; Kohane, Isaac; Psaty, Bruce M

    2015-03-15

    In 2013, the National Heart, Lung, and Blood Institute assembled a working group on epidemiology and population sciences from its Advisory Council and Board of External Experts. The working group was charged with making recommendations to the National Heart, Lung, and Blood Advisory Council about how the National Heart, Lung, and Blood Institute could take advantage of new scientific opportunities and delineate future directions for the epidemiology of heart, lung, blood, and sleep diseases. Seven actionable recommendations were proposed for consideration. The themes included 1) defining the compelling scientific questions and challenges in population sciences and epidemiology of heart, lung, blood, and sleep diseases; 2) developing methods and training mechanisms to integrate "big data" science into the practice of epidemiology; 3) creating a cohort consortium and inventory of major studies to optimize the efficient use of data and specimens; and 4) fostering a more open, competitive approach to evaluating large-scale longitudinal epidemiology and population studies. By building on the track record of success of the heart, lung, blood, and sleep cohorts to leverage new data science opportunities and encourage broad research and training partnerships, these recommendations lay a strong foundation for the transformation of heart, lung, blood, and sleep epidemiology. PMID:25743324

  2. beta-Adrenoceptor regulation in rat heart, lung and skin after chronic treatment with (--)-tertatolol or (--)-propranolol.

    PubMed

    Tan, Y Y; Summers, R J

    1995-12-01

    1. The effect of long-term treatment with the beta-adrenoceptor antagonists (--)-tertatolol and (--)-propranolol was studied. Sprague-Dawley rats were treated with either (--)-tertatolol (50 micrograms kg-1 hr-1), (--)-propranolol (250 micrograms kg-1 hr-1) or vehicle (1 mM HCl) for 14 days with osmotic minipumps implanted subcutaneously. 2. The mean daily systolic blood pressure and heart rate of rats treated with either (--)-tertatolol (108 +/- 1 mmHg/330 +/- 3 bpm) or (--)-propranolol (103 +/- 1 mmHg/330 +/- 2 bpm) were lower than in the control (126 +/- 1 mmHg/405 +/- 3 bpm, P < 0.001, n = 8-10) indicating the effectiveness of drug delivery. 3. Autoradiographic studies in areas of heart, lung and skin showed that beta-adrenoceptor populations were not significantly affected by the drug treatment (all regions P > 0.05). Nevertheless, the receptor population in the homogenates of (--)-tertatolol treated lung were halved (194 +/- 28 fmol mg protein-1 compared with a control value of 388 +/- 54 fmol mg protein-1, P < 0.01, n = 6). 4. In the presence of CGP 20712A, the left atrial inotropic and right atrial chronotropic responsiveness to (--)-isoprenaline were hypersensitive in both (--)-tertatolol and (--)-propranolol-treated groups (P < 0.005, ANCOVA). 5. (--)-Propranolol treated left ventricular free wall had lower basal [3H]-forskolin binding to adenylate cyclase (14.45 +/- 1.20 fmol mg protein-1 compared with a control value of 18.91 +/- 0.78 fmol mg protein-1, P = 0.01, n = 6). (--)-Tertatolol treatment had no effect on the basal binding. In the presence of the G-protein activators NaF and Gpp(NH)p, the enhancement of [3H]-forskolin binding did not differ between control and the drug treated groups. 6. Chronic (--)-tertatolol or (--)-propranolol treatment therefore did not produce an increase in receptors in heart, lung or skin but the beta-adrenoceptor-mediated responses were enhanced. In addition, [3H]-forskolin binding did not increase suggesting that the hypersensitivity was not due to changes in the number of receptors or adenylate cyclase. Hypersensitivity following beta-adrenoreceptor antagonist administration may therefore involve enhanced coupling of receptors to G-proteins. PMID:8920159

  3. Complication Probability Models for Radiation-Induced Heart Valvular Dysfunction: Do Heart-Lung Interactions Play a Role?

    PubMed Central

    Cella, Laura; Palma, Giuseppe; Deasy, Joseph O.; Oh, Jung Hun; Liuzzi, Raffaele; D’Avino, Vittoria; Conson, Manuel; Pugliese, Novella; Picardi, Marco; Salvatore, Marco; Pacelli, Roberto

    2014-01-01

    Purpose The purpose of this study is to compare different normal tissue complication probability (NTCP) models for predicting heart valve dysfunction (RVD) following thoracic irradiation. Methods All patients from our institutional Hodgkin lymphoma survivors database with analyzable datasets were included (n?=?90). All patients were treated with three-dimensional conformal radiotherapy with a median total dose of 32 Gy. The cardiac toxicity profile was available for each patient. Heart and lung dose-volume histograms (DVHs) were extracted and both organs were considered for Lyman-Kutcher-Burman (LKB) and Relative Seriality (RS) NTCP model fitting using maximum likelihood estimation. Bootstrap refitting was used to test the robustness of the model fit. Model performance was estimated using the area under the receiver operating characteristic curve (AUC). Results Using only heart-DVHs, parameter estimates were, for the LKB model: D50?=?32.8 Gy, n?=?0.16 and m?=?0.67; and for the RS model: D50?=?32.4 Gy, s?=?0.99 and ??=?0.42. AUC values were 0.67 for LKB and 0.66 for RS, respectively. Similar performance was obtained for models using only lung-DVHs (LKB: D50?=?33.2 Gy, n?=?0.01, m?=?0.19, AUC?=?0.68; RS: D50?=?24.4 Gy, s?=?0.99, ??=?2.12, AUC?=?0.66). Bootstrap result showed that the parameter fits for lung-LKB were extremely robust. A combined heart-lung LKB model was also tested and showed a minor improvement (AUC?=?0.70). However, the best performance was obtained using the previously determined multivariate regression model including maximum heart dose with increasing risk for larger heart and smaller lung volumes (AUC?=?0.82). Conclusions The risk of radiation induced valvular disease cannot be modeled using NTCP models only based on heart dose-volume distribution. A predictive model with an improved performance can be obtained but requires the inclusion of heart and lung volume terms, indicating that heart-lung interactions are apparently important for this endpoint. PMID:25360627

  4. Lung and Heart-Lung Transplantation: A Review of Progress and Current Status based on the Registry of the International Society for Heart and Lung Transplantation

    Microsoft Academic Search

    G. B. Haasler; J. D. Hosenpud

    The past decade has witnessed the rise of lung transplantation (LTx) as a viable clinical entity, and has seen substantial\\u000a revisions in the concepts underlying the techniques and indications for LTx and heart-lung transplantation (HLTx). From rather\\u000a inauspicious beginnings in the late 1960s and 1970s, LTx has emerged as a modality useful for treating both end-stage primary\\u000a lung disease in

  5. Report of the National Heart, Lung, and Blood Institute Working Group on research in adult congenital heart disease.

    PubMed

    Williams, Roberta G; Pearson, Gail D; Barst, Robyn J; Child, John S; del Nido, Pedro; Gersony, Welton M; Kuehl, Karen S; Landzberg, Michael J; Myerson, Merle; Neish, Steven R; Sahn, David J; Verstappen, Amy; Warnes, Carole A; Webb, Catherine L

    2006-02-21

    The Working Group on research in adult congenital heart disease (ACHD) was convened in September 2004 under the sponsorship of National Heart, Lung, and Blood Institute (NHLBI) and the Office of Rare Diseases, National Institutes of Health, Department of Health and Human Services, to make recommendations on research needs. The purpose of the Working Group was to advise the NHLBI on the current state of the science in ACHD and barriers to optimal clinical care, and to make specific recommendations for overcoming those barriers. The members of the Working Group were chosen to provide expert input on a broad range of research issues from both scientific and lay perspectives. The Working Group reviewed data on the epidemiology of ACHD, long-term outcomes of complex cardiovascular malformations, issues in assessing morphology and function with current imaging techniques, surgical and catheter-based interventions, management of related conditions including pregnancy and arrhythmias, quality of life, and informatics. After research and training barriers were discussed, the Working Group recommended outreach and educational programs for adults with congenital heart disease, a network of specialized adult congenital heart disease regional centers, technology development to support advances in imaging and modeling of abnormal structure and function, and a consensus on appropriate training for physicians to provide care for adults with congenital heart disease. PMID:16487831

  6. Registry of the Japanese Society of Lung and Heart-Lung Transplantation: official Japanese lung transplantation report, 2014.

    PubMed

    Sato, Masaaki; Okada, Yoshinori; Oto, Takahiro; Minami, Masato; Shiraishi, Takeshi; Nagayasu, Takeshi; Yoshino, Ichiro; Chida, Masayuki; Okumura, Meinoshin; Date, Hiroshi; Miyoshi, Shinichiro; Kondo, Takashi

    2014-10-01

    The number of organ donations after brain death has significantly increased since the revised Japanese Organ Transplant Law took effect in July 2010. Sixty-one lung transplantations were conducted throughout Japan in 2013, including 20 living-donor lung transplantations and 41 brain-dead-donor lung transplantations (23 bilateral lungs, 17 single lungs, and 1 heart-lung transplantation). The number of lung transplant candidates newly registered at the Japan Organ Transplantation Network also increased to 126 in 2013, suggesting a severe donor shortage in Japan. More than 60 % of offered brain-dead-donor, lungs were used for transplantation, indicating the effort of Japanese lung transplant centers to overcome the challenge of donor shortage. After lung transplantation, patients generally enjoyed a good quality of life with excellent survival of 86.2 % at 1 year, 79.6 % at 3 years, and 73.7 % at 5 years post-transplantation. There was no significant difference in patient survival between living-donor and brain-dead-donor lung transplantation. Early mortality of lung transplant recipients within 90 days was attributable to graft failure followed by infection, while long-term mortality was mostly explained by chronic lung allograft dysfunction (chronic rejection), infection, and malignancy. Eight lung transplant centers are currently approved to conduct lung transplantation in Japan (Tohoku, Dokkyo, Chiba, Kyoto, Osaka, Okayama, Fukuoka, and Nagasaki Universities). These centers are expected to continue to make a special effort to save critically ill patients waiting for lung transplantation. PMID:24842125

  7. Matrix biology of idiopathic pulmonary fibrosis: a workshop report of the national heart, lung, and blood institute.

    PubMed

    Thannickal, Victor J; Henke, Craig A; Horowitz, Jeffrey C; Noble, Paul W; Roman, Jesse; Sime, Patricia J; Zhou, Yong; Wells, Rebecca G; White, Eric S; Tschumperlin, Daniel J

    2014-06-01

    A hallmark of idiopathic pulmonary fibrosis (IPF) is excessive and disordered deposition of extracellular matrix. Although the lung extracellular matrix normally plays an essential role in development and maintenance of lung tissue through reciprocal interactions with resident cells, the disordered matrix in the diseased lung is increasingly recognized as an active and important contributor to IPF pathogenesis. This working group summary from a recently conducted National Heart, Lung, and Blood Institute strategic planning workshop for IPF research highlights recent advances, challenges, and opportunities in the study of matrix biology in IPF. Particular attention is given to the composition and mechanical properties of the matrix in normal and diseased lungs, and the biochemical and biomechanical influences exerted by pathological matrix. Recently developed model systems are also summarized as key tools for advancing our understanding of matrix biology in IPF. Emerging approaches to therapeutically target the matrix in preclinical and clinical settings are discussed, as are important concepts, such as alterations of the matrix with aging and the potential for the resolution of fibrosis. Specific recommendations for future studies in matrix biology of IPF are also proposed. PMID:24726499

  8. The role of cryotherapy for airway complications after lung and heart–lung transplantation 1 Presented at the 10th Annual Meeting of the European Association for Cardiothoracic Surgery, Prague, Czech Republic, 6–9 October, 1996. 1

    Microsoft Academic Search

    M. O. Maiwand; K. J. Zehr; C. M. Dyke; M. Peralta; S. Tadjkarimi; A. Khagani; M. H. Yacoub

    1997-01-01

    Objective: Although airway problems after lung and heart–lung transplantation have been greatly reduced due to changes in surgical technique, excessive granulation tissue at the anastomosis may threaten airway patency. Treatment options include electrocautery, dilation, laser coagulation and stent placement however, recurrence remains a problem. Cryotherapy, the controlled application of extreme cold, is effective at causing cell lysis in granulation tissue

  9. The Summer Institutes for Training in Biostatistics are sponsored by the National Heart, Lung, and Blood Institute (http://www.nhlbi.nih.gov/funding/training/redbook/sibsweb.htm) and the National Center for Research Resources.

    E-print Network

    Wisconsin at Madison, University of

    The Summer Institutes for Training in Biostatistics are sponsored by the National Heart, Lung IN BIOSTATISTICS (SIBS) Attention all mathematics, statistics, and science students seeking a summer opportunity the principles of applied biostatistics from recognized experts in the field and meet practicing biostatisticians

  10. The Summer Institutes for Training in Biostatistics are sponsored by the National Heart, Lung, and Blood Institute (http://www.nhlbi.nih.gov/funding/training/redbook/sibsweb.htm) and the National Center for Research Resources.

    E-print Network

    Karsai, Istvan

    The Summer Institutes for Training in Biostatistics are sponsored by the National Heart, Lung IN BIOSTATISTICS (SIBS) Attention all mathematics, statistics, and science students seeking a summer opportunity The opportunity to learn the principles of applied biostatistics from recognized experts in the field and meet

  11. Designing clinical trials to address the needs of childhood and adult asthma: the National Heart, Lung, and Blood Institute's AsthmaNet.

    PubMed

    Sutherland, E Rand; Busse, William W

    2014-01-01

    In 2008, the National Heart, Lung, and Blood Institute announced its intent to support a new asthma network known as AsthmaNet. This clinical trials consortium, now in its fifth year, has been charged with developing and executing clinical trials to address the most important asthma management questions and identify new treatment approaches in pediatric and adult patients. This review will discuss the organization of AsthmaNet and the scientific context in which the network was developed and began its work, report the results of an internal priority-setting exercise designed to guide the network's scientific strategy, and highlight the portfolio of clinical trials, proof-of-concept studies, and mechanistic studies planned for the 7-year period of the network to update the global asthma community regarding the progress and processes of the network. PMID:24369797

  12. Ethical and practical guidelines for reporting genetic research results to study participants: updated guidelines from a National Heart, Lung, and Blood Institute working group.

    PubMed

    Fabsitz, Richard R; McGuire, Amy; Sharp, Richard R; Puggal, Mona; Beskow, Laura M; Biesecker, Leslie G; Bookman, Ebony; Burke, Wylie; Burchard, Esteban Gonzalez; Church, George; Clayton, Ellen Wright; Eckfeldt, John H; Fernandez, Conrad V; Fisher, Rebecca; Fullerton, Stephanie M; Gabriel, Stacey; Gachupin, Francine; James, Cynthia; Jarvik, Gail P; Kittles, Rick; Leib, Jennifer R; O'Donnell, Christopher; O'Rourke, P Pearl; Rodriguez, Laura Lyman; Schully, Sheri D; Shuldiner, Alan R; Sze, Rebecca K F; Thakuria, Joseph V; Wolf, Susan M; Burke, Gregory L

    2010-12-01

    In January 2009, the National Heart, Lung, and Blood Institute convened a 28-member multidisciplinary Working Group to update the recommendations of a 2004 National Heart, Lung, and Blood Institute Working Group focused on Guidelines to the Return of Genetic Research Results. Changes in the genetic and societal landscape over the intervening 5 years raise multiple questions and challenges. The group noted the complex issues arising from the fact that technological and bioinformatic progress has made it possible to obtain considerable information on individuals that would not have been possible a decade ago. Although unable to reach consensus on a number of issues, the working group produced 5 recommendations. The working group offers 2 recommendations addressing the criteria necessary to determine when genetic results should and may be returned to study participants, respectively. In addition, it suggests that a time limit be established to limit the duration of obligation of investigators to return genetic research results. The group recommends the creation of a central body, or bodies, to provide guidance on when genetic research results are associated with sufficient risk and have established clinical utility to justify their return to study participants. The final recommendation urges investigators to engage the broader community when dealing with identifiable communities to advise them on the return of aggregate and individual research results. Creation of an entity charged to provide guidance to institutional review boards, investigators, research institutions, and research sponsors would provide rigorous review of available data, promote standardization of study policies regarding return of genetic research results, and enable investigators and study participants to clarify and share expectations for the handling of this increasingly valuable information with appropriate respect for the rights and needs of participants. PMID:21156933

  13. Report of a National Heart, Lung, And Blood Institute Workshop: heterogeneity in cardiometabolic risk in Asian Americans In the U.S. Opportunities for research.

    PubMed

    Narayan, K M Venkat; Aviles-Santa, Larissa; Oza-Frank, Reena; Pandey, Mona; Curb, J David; McNeely, Marguerite; Araneta, Maria Rosario G; Palaniappan, Latha; Rajpathak, Swapnil; Barrett-Connor, Elizabeth

    2010-03-01

    The Asian and Pacific Islander population (Asian Americans) in the U.S. has increased dramatically in the last few decades. Yet, data on cardiovascular disease (CVD) in this population are scarce. The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health conducted an Expert Workshop to: 1) assess the importance of studying CVD in Asian Americans in the U.S.; and 2) consider strategic options for further investigations of CVD in this population. There is considerable geographical, ethnic, cultural, and genetic diversity within this population. Limited data also suggest striking differences in the risk of CVD, obesity, type 2 diabetes mellitus, and other CVD risk factors across the Asian-American population. The Asian-American population is a new diverse pool with less contemporary genetic and cultural admixture relative to groups that have lived in the U.S. for generations, plus it is diverse in lifestyle including culture, diet, and family structure. This diversity provides a window of opportunity for research on genes and gene-environment interactions and also to investigate how acculturation/assimilation to U.S. lifestyles affects health and CVD risk among relatively homogenous groups of recent immigrants. Given the heterogeneity in body weight, body size, and CVD risk, the Asian-American population in the U.S. offers a unique model to study the interaction and relationships between visceral adiposity and adipose tissue distribution and beta cell function, insulin resistance, and atherosclerosis. PMID:20202512

  14. An Update from the United States National Heart, Lung, and Blood Institute-funded Production Assistance for Cellular Therapies (PACT) Program: A Decade of Cell Therapy

    PubMed Central

    Wood, D; Wesselschmidt, R; Hematti, P; Gee, AP; Rooney, C; Silberstein, L; Armant, M; Couture, L; Wagner, J; McKenna, D; Hei, D; Heath Mondoro, T; Welniak, L; Lindblad, R

    2014-01-01

    Recognizing the challenges faced by researchers and clinicians working in the field of cellular therapy, the National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health, established the Production Assistance for Cellular Therapies (PACT) program in 2003 and expanded it in 2010. The PACT program provides both clinical product manufacturing support that furthers the mission of NHLBI in the areas of cardiac, lung, and blood diseases and broad support of translational development across all disease areas to serve the entire cell therapy community. The program also provides access to expertise in project management, regulatory affairs, and quality assurance and control. Education initiatives include webinars, cell processing facility-hosted workshops, national workshops, and active participation and leadership within the cell therapy community through collaboration with other cell therapy organizations and academia. So far, over 650 PACT-manufactured cell therapy products have been administered in 32 clinical trials for a range of illnesses and diseases such as acute myocardial infarction, sickle cell disease, and graft-versus-host disease. PMID:24655892

  15. Comparison of bare-metal stents and drug-eluting stents in coronary ostial lesions (from the National Heart, Lung, and Blood Institute Dynamic Registry).

    PubMed

    Vasaiwala, Samip; Vlachos, Helen; Selzer, Faith; Marroquin, Oscar; Mulukutla, Suresh; Abbott, J Dawn; Williams, David O

    2012-10-15

    We compared the effectiveness of drug-eluting stents (DESs) to bare-metal stents (BMSs) in ostial lesions from an unrestricted patient cohort with 3-year follow-up. DESs have proved more effective at decreasing repeat revascularization rates compared to BMSs in patients with uncomplicated coronary artery disease. Whether DESs provide similar benefits in ostial lesions is not clearly defined. We analyzed data from 775 patients in the National, Heart, Lung, and Blood Institute Dynamic Registry undergoing stenting of ostial lesions with DESs or BMSs. Patients were followed for 3 years for the occurrence of myocardial infarction (MI), repeat revascularization (coronary bypass surgery/repeat percutaneous coronary intervention), and death. In total 439 patients had 464 ostial lesions treated with BMSs and 336 patients had 351 ostial lesions treated with DESs. Adjusted DES versus BMS 3-year hazard ratios were 1.03 (95% confidence interval 0.60 to 1.78, p = 0.90) for death, 1.40 (0.83 to 2.37, p = 0.21) for MI, and 0.81 (0.59 to 1.11, p = 0.19) for repeat revascularization. In patients undergoing percutaneous coronary intervention for aorto-ostial disease (n = 200), death and repeat revascularization did not differ between stent types, but DES-treated patients had more MI during follow-up. For coronary ostial disease (n = 574), 3-year observed rates of death or MI did not differ; however, repeat revascularization was more common in the BMS group. In conclusion, use of DESs for ostial lesions was associated with no difference in the hazard of death, MI, or overall rates of repeat revascularization compared to BMS use. PMID:22762712

  16. Focused sonographic examination of the heart, lungs and deep veins in an unselected population of acute admitted patients with respiratory symptoms: a protocol for a prospective, blinded, randomised controlled trial

    PubMed Central

    Sloth, Erik; Lassen, Annmarie Touborg; Christensen, René dePont; Lambrechtsen, Jess; Madsen, Poul Henning; Henriksen, Daniel Pilsgaard; Davidsen, Jesper Rømhild; Rasmussen, Finn

    2012-01-01

    Introduction Patients admitted to hospital with acute respiratory symptoms remain a diagnostic challenge for the emergency physician. The use of focused sonography may improve the initial diagnostics, as most of the diseases, commonly seen and misdiagnosed in patients with acute respiratory symptoms, can be diagnosed with sonography. The protocol describes a prospective, blinded, randomised controlled trial that aims to assess the diagnostic impact of a pragmatic implementation of focused sonography of the heart, lungs and deep veins as a diagnostic modality in acute admitted patients with respiratory symptoms. Methods and analysis The primary outcome of the study is the number of patients with a correct presumptive diagnosis within 4?h of admission to the emergency department. The patient is randomised to either an intervention or a control group. In the intervention group, the usual initial diagnostic work up is supplemented by focused sonographic examination of the heart, lungs and deep veins of the legs. In the control group, usual diagnostic work up is performed. The ?2 test, alternatively the Fischer exact test will be used, to establish whether there is a difference in the distribution of the total number of patients with a correct/incorrect ‘4?h’ presumptive diagnosis in the control group and in the intervention group. Ethics and dissemination This clinical trial is performed according to the Declaration of Helsinki and has been approved by the Regional Scientific Ethical Committee for Southern Denmark and the Danish Data Protection Agency. The results of the trial will be published according to the CONSORT statement with the extension for pragmatic trials. The results of the trial will be published in a peer-reviewed scientific journal regardless of the outcome. Trial registration number This study is registered at http://clinicaltrials.gov, registration number NCT01486394. PMID:22649177

  17. Simple Machines

    NSDL National Science Digital Library

    Mr. Oldroyd

    2007-09-26

    Online Simple Machines Assignment OBJECTIVES: Student\\'s will be able to name and describe all seven simple machines. Students will be able to identify simple machines that they use everyday. Example: Clock = Gear INSTRUCTIONS: 1. Click on the Simple Machines Glossary page and familiarize yourself with the seven simple machines. Simple Machines Glossary Page 2. Students are to click on ...

  18. Simple Machines

    NSDL National Science Digital Library

    AWOL

    2006-11-15

    This activity is designed to learn about simple machines and to have fun doing so! First, use this website to learn backround information on the basics of simple machines. Try the quiz! Simple Machines Learning Site Next, play a game that tests your ability to identify simple machines.... Edheads: Simple Machines Finally, view this video to see how students your age used applied simple machines to do a cool task... Building Simple Machines: A Glass of Milk, Please ...

  19. Production Assistance for Cellular Therapies (PACT): five-year experience from the United States National Heart, Lung, and Blood Institute (NHLBI) contract research program in cell and tissue therapies

    PubMed Central

    Reed, William; Noga, Stephen J.; Gee, Adrian P.; Rooney, Cliona M.; Wagner, John E.; McCullough, Jeffrey; McKenna, David H.; Whiteside, Theresa L.; Donnenberg, Albert D.; Baker, Acacia K.; Lindblad, Robert W.; Wagner, Elizabeth L.; Mondoro, Traci Heath

    2014-01-01

    BACKGROUND In 2002, the US National Heart, Lung, and Blood Institute (NHLBI) conducted a workshop to determine needs of the cell therapy community. A consensus emerged that improved access to cGMP facilities, regulatory assistance, and training would foster the advancement of cellular therapy. STUDY DESIGN AND METHODS A 2003 NHLBI request for proposals resulted in four contracts being awarded to three cell-manufacturing facilities (Baylor College of Medicine, University of Minnesota, and University of Pittsburgh) and one administrative center (The EMMES Corporation). As a result, Production Assistance for Cellular Therapies (PACT) was formed. RESULTS As of October 1, 2008, PACT has received 65 preliminary applications of which 45 have been approved for product manufacture. A variety of cell therapies are represented including T-regulatory cells, natural killer cells, adipose-derived stem cells, cardiac progenitor cells for cardiac disease, hematopoietic progenitor cells (HPCs) for central nervous system applications, cytotoxic T lymphocytes, and dendritic cells. A total of 169 products have been administered under 12 applications and 2 reagents were manufactured and delivered. Fourteen peer-reviewed publications and 15 abstracts have resulted from the PACT project to date. A cell therapy textbook is nearly complete. PACT technical projects have addressed assay development, rapid endotoxin testing, shipping of cell products, and CD34+ HPC isolation from low-volume marrow. Educational Web seminars and onsite training through workshops have been conducted. CONCLUSIONS PACT is an active and successful cell therapy manufacturing resource in the United States, addressing research and training while forging relationships among academia, industry, and participating institutions. PMID:19170985

  20. Machine Learning

    Microsoft Academic Search

    Xin Yao; Yong Liu

    Machine learning is a very active sub-field of artificial intelligence concerned with the development of computational models\\u000a of learning. Machine learning is inspired by the work in several disciplines: cognitive sciences, computer science, statistics,\\u000a computational complexity, information theory, control theory, philosophy, and biology. Simply speaking, machine learning is\\u000a learning by machine. From a computational point of view, machine learning refers

  1. The vascular surgeon-scientist: a 15-year report of the Society for Vascular Surgery Foundation/National Heart, Lung, and Blood Institute-mentored Career Development Award Program.

    PubMed

    Kibbe, Melina R; Dardik, Alan; Velazquez, Omaida C; Conte, Michael S

    2015-04-01

    The Society for Vascular Surgery (SVS) Foundation partnered with the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH) in 1999 to initiate a competitive career development program that provides a financial supplement to surgeon-scientists receiving NIH K08 or K23 career development awards. Because the program has been in existence for 15 years, a review of the program's success has been performed. Between 1999 and 2013, 41 faculty members applied to the SVS Foundation program, and 29 from 21 different institutions were selected as awardees, resulting in a 71% success rate. Three women (10%) were among the 29 awardees. Nine awardees (31%) were supported by prior NIH F32 or T32 training grants. Awardees received their K award at an average of 3.5 years from the start of their faculty position, at the average age of 39.8 years. Thirteen awardees (45%) have subsequently received NIH R01 awards and five (17%) have received Veterans Affairs Merit Awards. Awardees received their first R01 at an average of 5.8 years after the start of their K award at the average age of 45.2 years. The SVS Foundation committed $9,350,000 to the Career Development Award Program. Awardees subsequently secured $45,108,174 in NIH and Veterans Affairs funds, resulting in a 4.8-fold financial return on investment for the SVS Foundation program. Overall, 23 awardees (79%) were promoted from assistant to associate professor in an average of 5.9 years, and 10 (34%) were promoted from associate professor to professor in an average of 5.2 years. Six awardees (21%) hold endowed professorships and four (14%) have secured tenure. Many of the awardees hold positions of leadership, including 12 (41%) as division chief and two (7%) as vice chair within a department of surgery. Eight (28%) awardees have served as president of a regional or national society. Lastly, 47 postdoctoral trainees have been mentored by recipients of the SVS Foundation Career Development Program on training grants or postdoctoral research fellowships. The SVS Foundation Career Development Program has been an effective vehicle to promote the development and independence of vascular surgeon-scientists in the field of academic vascular surgery. PMID:25814368

  2. Simple Machines

    NSDL National Science Digital Library

    At this website, EdHeads, a nonprofit, offers five interactive, animated modules to educate second- through sixth-graders about simple machines. By identifying the many machines located throughout a house, students can learn about fulcrums, wheel and axles, levers, pulleys, inclined planes, and much more. The website is equipped with simple animations to help children understand how the machines work. After students have a handle on simple machines, they can begin to see how they work together to create compound machines. The website also provides a brief glossary summarizing nine types of simple machines. This site is also reviewed in the February 18, 2005_NSDL Physical Sciences Report_.

  3. National Heart, Lung, and Blood Institute

    MedlinePLUS

    ... neighborhood’s resources and obesity rates. Learn more . Image: Women’s Health Initiative Description: NHLBI salutes the heroines who made the Women’s Health Initiative possible. Meet some of the women who ...

  4. National Heart, Lung, and Blood Institute

    E-print Network

    Bandettini, Peter A.

    focus on one thing: weight loss. However, if you set goals, eat healthy foods, and are physically active, then you may be more successful at losing weight. Weight Loss Goals Setting the right goals is an important is a reasonable and safe weight loss. · Maintaining a modest weight loss over a longer period of time is better

  5. SIMPLE MACHINES

    NSDL National Science Digital Library

    Mrs. MacHose

    2007-03-10

    You will be learning about several types of simple machines. Have fun!! Review the first website (which is right here!! Simple machines) . It has information about simple machines. DON\\"T click until you read all directions!!! Prepare to discuss each type in class. You will need to take some basic notes about each machine, using a bubble-map format. Don\\'t forget ...

  6. Sewing Machines!!

    NSDL National Science Digital Library

    Miss. Walker

    2008-10-20

    Learn the Parts of a Sewing Machine This should help you understand the history of sewing machines and how they work. For this assignment, answer these questions on a sheet of paper and bring it to class. Click on this link to go to a site which will briefly explain the history of the sewing machine: wikipedia Was ...

  7. Simple Machines

    NSDL National Science Digital Library

    This is a lesson about simple machines and how they relate to robots. Learners will gain an understanding of simple machines and how they may be used in our everyday lives. Students will also have an opportunity to design a Rube Goldberg Machine of their own. This is lesson 10 of 16 in the MarsBots learning module.

  8. Electrostatic Machines

    NSDL National Science Digital Library

    De Queiroz, Antonio Carlos M.

    This website from Antonio Carlos M. De Queiroz, an associate professor at the Federal University of Rio de Janeiro, illustrates a number of different electrostatic machines. The site includes details and images of machines built by the professor as well as many other historical machines of this type. Some information is also available in Portugese.

  9. Machine Learning

    Microsoft Academic Search

    Crina Grosan; Ajith Abraham

    \\u000a Machine Learning[6][8][12] is concerned with the study of building computer programs that automatically improve and\\/or adapt\\u000a their performance through experience. Machine learning can be thought of as “programming by example” [11]. Machine learning\\u000a has many common things with other domains such as statistics and probability theory (understanding the phenomena that have\\u000a generated the data), data mining (finding patterns in the

  10. Precision Machining

    NSDL National Science Digital Library

    Leske, Cavin.

    Basic machining processes are introduced on a Web site that is devoted to engineering fundamentals (1). Descriptions and illustrations of drilling, turning, grinding, and other common processes are provided for people with little to no prior machining knowledge. A waterjet is a non-traditional machining technology that uses high pressure streams of water with abrasive additives rather than solid cutting instruments to slice through metal and other materials. An in-depth discussion of waterjet operation and applications is available from Southern Methodist University (2). Waterjets are often cited as being much more precise than traditional machining techniques. The Waterjet Video Vault (3) contains clips of waterjet machines in action. The video of the foam cutting procedure is especially interesting, as it shows how quick and accurate the machining process can be. An online guide to cross process machining, which incorporates elements from various conventional and unconventional techniques, is provided by the Mechanical Engineering Department at Columbia University (4). Some remarkable and innovative techniques that have surfaced over the past few years are outlined, including underwater laser machining and plasma-assisted machining. Entirely different and exotic machining techniques are required for creating microelectromechanical systems (MEMS) and other extremely small devices. The Caltech Micromachining Laboratory (5) maintains an archive of research highlights and papers on its homepage, including a paper on a MEMS-driven flapping wing for a palm-sized aerial vehicle. An online article from Modern Machine Shop (6) outlines some new technologies and research in the area of high speed machining. A particularly interesting section of the article describes a system developed at the University of Florida that aims to enable micromachining to achieve rotational speeds of standard machining processes, specifically up to a half million rotations per minute. Cutting edge waterjet innovations are the subject of a February 2003 feature from a publication of the Society of Manufacturing Engineers (7). Extremely high pressure nozzles are being developed to improve cutting speed, and enhanced software for controlling machine movements is also a focus of study. This news article (8) from June 20, 2003 describes an electrochemical machining process that is being used to fabricate complex nanostructures. The work, produced by German and U.S. researchers, has the potential to compete with current lithographic processes.

  11. Simple Machines

    NSDL National Science Digital Library

    KET

    2010-11-16

    How do you get a glove and a ball up to your tree house? One answer is to use a pulley. A pulley is a simple machine. In this original KET interactive, children learn about the basic workings of three simple machines.

  12. Excavating machines

    SciTech Connect

    Plummer, D.

    1980-10-21

    The excavating machine has a cutter carrying boom carried by a boom support member which can be swung about an axis extending in the direction of the roadway. The machine includes a cutter unit and a stay unit each of which is releasably anchorable in the roadway and each of which can be advanced relative to the other unit.

  13. Machine therapy

    E-print Network

    Dobson, Kelly E. (Kelly Elizabeth), 1970-

    2007-01-01

    Machine Therapy is a new practice combining art, design, psychoanalysis, and engineering work in ways that access and reveal the vital, though often unnoticed, relevance of people's interactions and relationships with ...

  14. Math Machines

    NSDL National Science Digital Library

    The mission of the Math Machines organization is to "improve the quality of mathematical education, enhance the transfer of mathematical thinking into other classes, and increase students' ability to apply rigorous mathematics outside the classroom." Their website supports a National Science Foundation ATE grant-supported project designed to improve teaching in the areas of Mathematics, Science, and Technology at the high school and college levels. This improved learning results from using math, science, and technology principles to build and control various machines such as pointers and robots or "math machines", which are simple devices that provide an immediate, physical, dynamic expression to abstract mathematical equations. The website provides information links on Educational Theory, Classroom Activities, Project Workshops, Calculators & Programs, and Machine Construction Instructions for Building: Closed Circuits, Servo Motors, Controllers, Robot Boards and more. There is also contact information, an FAQ section, as well as upcoming events.

  15. Simple Machines

    NSDL National Science Digital Library

    This series of three interactive, multimedia activities introduce and demonstrate the properties of six simple machines. Specifically, the lessons show how levers, pulleys, inclined planes, screws, wheels and axles, and wedges can reduce the amount of work done by humans. After learning about the characteristics of each classification, users can try to find the simple machines that make up a lawn mower. By inspecting the mower from different angles, several simple machines are revealed and must be identified. The final activity lets users test their knowledge of the mechanics of simple machines. Following a builder through each stage of constructing a tree house, users can apply equations to determine the mechanical advantage supplied by using the tools.

  16. Monel Machining

    NASA Technical Reports Server (NTRS)

    1983-01-01

    Castle Industries, Inc. is a small machine shop manufacturing replacement plumbing repair parts, such as faucet, tub and ballcock seats. Therese Castley, president of Castle decided to introduce Monel because it offered a chance to improve competitiveness and expand the product line. Before expanding, Castley sought NERAC assistance on Monel technology. NERAC (New England Research Application Center) provided an information package which proved very helpful. The NASA database was included in NERAC's search and yielded a wealth of information on machining Monel.

  17. Workout Machine

    NASA Technical Reports Server (NTRS)

    1995-01-01

    The Orbotron is a tri-axle exercise machine patterned after a NASA training simulator for astronaut orientation in the microgravity of space. It has three orbiting rings corresponding to roll, pitch and yaw. The user is in the middle of the inner ring with the stomach remaining in the center of all axes, eliminating dizziness. Human power starts the rings spinning, unlike the NASA air-powered system. Marketed by Fantasy Factory (formerly Orbotron, Inc.), the machine can improve aerobic capacity, strength and endurance in five to seven minute workouts.

  18. Function Machine

    NSDL National Science Digital Library

    2011-01-01

    This Java applet allows learners to explore simple linear functions. Students determine the algebraic form of a linear equation by entering inputs into the machine and by looking for patterns in the outputs. The function rules available are: integers from -10 to 10 are either added to, subtracted from, or multiplied by the input x to yield the output y.

  19. Decoding Machine

    NSDL National Science Digital Library

    2012-10-22

    In this math lesson, learners explore variables and their uses. Learners pretend to be FBI agents and make a TOP SECRET tool that enables them to decode and find the values of hidden messages and words. Learners make their simple "decoding machines" out of paper and tape.

  20. Machine Learning

    NASA Astrophysics Data System (ADS)

    Hoffmann, Achim; Mahidadia, Ashesh

    The purpose of this chapter is to present fundamental ideas and techniques of machine learning suitable for the field of this book, i.e., for automated scientific discovery. The chapter focuses on those symbolic machine learning methods, which produce results that are suitable to be interpreted and understood by humans. This is particularly important in the context of automated scientific discovery as the scientific theories to be produced by machines are usually meant to be interpreted by humans. This chapter contains some of the most influential ideas and concepts in machine learning research to give the reader a basic insight into the field. After the introduction in Sect. 1, general ideas of how learning problems can be framed are given in Sect. 2. The section provides useful perspectives to better understand what learning algorithms actually do. Section 3 presents the Version space model which is an early learning algorithm as well as a conceptual framework, that provides important insight into the general mechanisms behind most learning algorithms. In section 4, a family of learning algorithms, the AQ family for learning classification rules is presented. The AQ family belongs to the early approaches in machine learning. The next, Sect. 5 presents the basic principles of decision tree learners. Decision tree learners belong to the most influential class of inductive learning algorithms today. Finally, a more recent group of learning systems are presented in Sect. 6, which learn relational concepts within the framework of logic programming. This is a particularly interesting group of learning systems since the framework allows also to incorporate background knowledge which may assist in generalisation. Section 7 discusses Association Rules - a technique that comes from the related field of Data mining. Section 8 presents the basic idea of the Naive Bayesian Classifier. While this is a very popular learning technique, the learning result is not well suited for human comprehension as it is essentially a large collection of probability values. In Sect. 9, we present a generic method for improving accuracy of a given learner by generatingmultiple classifiers using variations of the training data. While this works well in most cases, the resulting classifiers have significantly increased complexity and, hence, tend to destroy the human readability of the learning result that a single learner may produce. Section 10 contains a summary, mentions briefly other techniques not discussed in this chapter and presents outlook on the potential of machine learning in the future.

  1. Simple Machines

    NSDL National Science Digital Library

    Wakild, Terri

    The goals for this introduction activity to Simple Machines are.: - Generate scientific questions about the world based on observation - Design and conduct scientific investigations - Use tools and equipment appropriate to scientific investigations - Use sources of information in support of scientific investigation - Write and follow procedures in the form of step-by-step instructions, formulas, flow diagram, and sketches - Show how common themes of science, mathematics, and technology apply in real-world contexts - Recognize the contributions made in science by cultures and individuals of diverse backgrounds - Design strategies for moving objects by application of forces, including the use of simple machines MERC Online Reviewer Comments: Good computer activities for under-represented students who want to pursue manufacturing education. Distance Learning is a plus.

  2. Simple Machines

    NSDL National Science Digital Library

    Miss Stewart

    2010-03-24

    Can you identify the six types of simple machines? 1. What do you know about Inclined Planes? Draw an example on your graphic organizer and state one fact.Inclined Plane 2. What do you know about levers? Draw an example on your graphic organizer and state one fact.Lever. 3. What do you know about pulleys? Draw an example on your graphic organizer and ...

  3. Mining machine

    SciTech Connect

    Mendola, C.F.

    1981-11-03

    A mining machine is disclosed in which a cutting drum undercuts a vein of coal and side relief cutters make vertical kerfs in the vein upwardly from the undercut. A chisel plate is forced into the coal vein and breaks loose the material above the undercut and between the side relief cuts. The coal falls into conveyors and is loaded into mine shuttle cars for removal from the mine. The side relief cutters and chisel assembly are progressively raised to extract higher levels of coal from the vein until the desired roof height has been reached. The tramming track assembly, which propels the machine, may be rotated 90/sup 0/ to permit extraction from the vein immediately adjacent the initial extraction. All power supplied near the working face of the vein is hydraulic to minimize the risk of fire or explosion, and a water spray system minimizes dust circulation. Hydraulic roof and floor jacks are provided to increase the stability of the mining machine when exceptionally hard material is encountered in the coal vein.

  4. Learning about Simple Machines

    NSDL National Science Digital Library

    Mrs. Keller

    2010-01-17

    This activity is designed to learn about simple machines and to have fun doing so! First, use this website to learn backround information on the basics of simple machines. Try the quiz! Simple Machines Learning Site Next, play a game that tests your ability to identify simple machines.... Edheads: Simple Machines Finally, view this video to see how students your age used applied simple machines to do a cool task... Building Simple Machines: A Glass of Milk, Please ...

  5. Machine Design

    NSDL National Science Digital Library

    This website, the homepage of Machine Design.com, contains resources on a variety of information for engineers and technicians related to devices, components, design applications, products, and systems in the manufacturing technology sector. The site also features a CAD library, eBooks, audiovisual aids, webinars, whitepapers and a reference center. Some of the resources require a free login. The page offers an RSS feed to keep users up to date on new resources. A free login may be required to access some of these items.

  6. Course info Machine Learning

    E-print Network

    Shi, Qinfeng "Javen"

    Course info Machine Learning Real life problems Lecture 1: Machine Learning Problem Qinfeng (Javen) Shi 28 July 2014 Intro. to Stats. Machine Learning COMP SCI 4401/7401 Qinfeng (Javen) Shi Lecture 1: Machine Learning Problem #12;Course info Machine Learning Real life problems Table of Contents I 1 Course

  7. 2002 SPS MACHINE STATISTICS

    E-print Network

    Desforges, B; CERN. Geneva. SPS and LHC Division

    2002-01-01

    2002 SPS MACHINE STATISTICS Fixed Target Periods with Protons (comments on machine operation, tables and diagrams, comparative tables and diagrams) Fixed Target Periods with Ions (comments on machine operation, tables and diagrams, comparative tables and diagrams)

  8. Mind & Machine

    NSDL National Science Digital Library

    Dunn, Ashley.

    Mind & Machine is a weekly column provided by Ashley Dunn for the New York Times Cybertimes that discusses topics related to computing, technology, and the Internet. Recent columns have addressed the topics of the development of Internet telephony, possible futures of user interfaces, the history of technology and standards, and the Internet as a vehicle for community. Articles are well written, opinionated, and thought provoking. Mr. Dunn is a free lance writer who has written for such papers as the New York Times, the Los Angeles Times, the Seattle Post-Intelligencer, and the South China Morning Post. Note that the site is available only upon registration and is free of charge only in the US.

  9. Machine musicianship

    NASA Astrophysics Data System (ADS)

    Rowe, Robert

    2002-05-01

    The training of musicians begins by teaching basic musical concepts, a collection of knowledge commonly known as musicianship. Computer programs designed to implement musical skills (e.g., to make sense of what they hear, perform music expressively, or compose convincing pieces) can similarly benefit from access to a fundamental level of musicianship. Recent research in music cognition, artificial intelligence, and music theory has produced a repertoire of techniques that can make the behavior of computer programs more musical. Many of these were presented in a recently published book/CD-ROM entitled Machine Musicianship. For use in interactive music systems, we are interested in those which are fast enough to run in real time and that need only make reference to the material as it appears in sequence. This talk will review several applications that are able to identify the tonal center of musical material during performance. Beyond this specific task, the design of real-time algorithmic listening through the concurrent operation of several connected analyzers is examined. The presentation includes discussion of a library of C++ objects that can be combined to perform interactive listening and a demonstration of their capability.

  10. Machine Shop Lathes.

    ERIC Educational Resources Information Center

    Dunn, James

    This guide, the second in a series of five machine shop curriculum manuals, was designed for use in machine shop courses in Oklahoma. The purpose of the manual is to equip students with basic knowledge and skills that will enable them to enter the machine trade at the machine-operator level. The curriculum is designed so that it can be used in…

  11. Hybrid Quantum Cloning Machine

    E-print Network

    Satyabrata Adhikari; A. K. Pati; Indranil Chakrabarty; B. S. Choudhury

    2007-06-14

    In this work, we introduce a special kind of quantum cloning machine called Hybrid quantum cloning machine. The introduced Hybrid quantum cloning machine or transformation is nothing but a combination of pre-existing quantum cloning transformations. In this sense it creates its own identity in the field of quantum cloners. Hybrid quantum cloning machine can be of two types: (i) State dependent and (ii) State independent or Universal. We study here the above two types of Hybrid quantum cloning machines. Later we will show that the state dependent hybrid quantum-cloning machine can be applied on only four input states. We will also find in this paper another asymmetric universal quantum cloning machine constructed from the combination of optimal universal B-H quantum cloning machine and universal anti-cloning machine. The fidelities of the two outputs are different and their values lie in the neighborhood of ${5/6} $

  12. LISP Machine Progress Report

    E-print Network

    Bawden, Alan

    1977-08-01

    This informal paper introduces the LISP Machine, describes the goals and current status of the project, and explicates some of the key ideas. It covers the LISP machine implementation, LISP as a system language, ...

  13. Infinite Time Turing Machines

    Microsoft Academic Search

    Joel David Hamkins

    2002-01-01

    Infinite time Turing machines extend the operation of ordinary Turing machines into transfinite ordinal time. By doing so, they provide a natural model of infinitary computability, a theoretical setting for the analysis of the power and limitations of supertask algorithms.

  14. What is Machine Learning? About the Course Example Machine Learning

    E-print Network

    Kjellström, Hedvig

    What is Machine Learning? About the Course Example Machine Learning DD2431 ¨Orjan Ekeberg Oct­Dec, 2007 #12;What is Machine Learning? About the Course Example 1 What is Machine Learning? Definition A Hypothetical Project #12;What is Machine Learning? About the Course Example 1 What is Machine Learning

  15. What is Machine Learning? About the Course Example Machine Learning

    E-print Network

    Kjellström, Hedvig

    What is Machine Learning? About the Course Example Machine Learning DD2431 ¨Orjan Ekeberg Oct­Dec, 2008 What is Machine Learning? About the Course Example 1 What is Machine Learning? Definition A Hypothetical Project What is Machine Learning? About the Course Example 1 What is Machine Learning? Definition

  16. What is Machine Learning? About the Course Example Machine Learning

    E-print Network

    Kjellström, Hedvig

    What is Machine Learning? About the Course Example Machine Learning DD2431 ¨Orjan Ekeberg Oct­Dec, 2008 #12;What is Machine Learning? About the Course Example 1 What is Machine Learning? Definition A Hypothetical Project #12;What is Machine Learning? About the Course Example 1 What is Machine Learning

  17. What is Machine Learning? About the Course Example Machine Learning

    E-print Network

    Kjellström, Hedvig

    What is Machine Learning? About the Course Example Machine Learning DD2431 ¨Orjan Ekeberg Oct­Dec, 2007 What is Machine Learning? About the Course Example 1 What is Machine Learning? Definition A Hypothetical Project What is Machine Learning? About the Course Example 1 What is Machine Learning? Definition

  18. Primary Masters in Machine Learning

    E-print Network

    Primary Masters in Machine Learning Student Handbook #12;#12;Page 1 Masters in Machine Learning:.......................................................................................8 Machine Learning Journal Club ..................................................................12 #12;Page 3 Introduction The field of machine learning is concerned with the question of how

  19. Stochastic Optimization for Machine Learning

    E-print Network

    Powell, Warren B.

    Stochastic Optimization for Machine Learning ICML 2010, Haifa, Israel Tutorial by Nati Srebro Descent: formulation, analysis and use in machine learning · Learn about extensions and generalizations, and their Machine Learning counterparts Main Goal: Machine Learning is Stochastic Optimization #12;Outline

  20. Covering selfish machines

    Microsoft Academic Search

    Leah Epstein; Rob Van Stee

    2006-01-01

    We consider the machine covering problem for selfish related machines. For a constant number of machines, m, we show a monotone polynomial time approximation scheme (PTAS) with running time that is linear in the number of jobs. It uses a new technique for reducing the number of jobs while remaining close to the optimal solution. We also present an FPTAS

  1. Automated Slide Staining Machine

    PubMed Central

    Drew, W. Lawrence; Pedersen, Anders N.; Roy, Jacques J.

    1972-01-01

    A machine is described which can perform the Gram stain. Comparison of slides stained by machine versus hand revealed no difference in reproducibility or accuracy. In addition to providing clean, dry, uniformly stained slides, the machine saves 24 sec per slide when compared with a hand staining technique. Images PMID:4110426

  2. Review on ultrasonic machining

    Microsoft Academic Search

    T. B. Thoe; D. K. Aspinwall; M. L. H. Wise

    1998-01-01

    Ultrasonic machining is of particular interest for the cutting of non-conductive, brittle workpiece materials such as engineering ceramics. Unlike other non-traditional processes such as laser beam, and electrical discharge machining, etc., ultrasonic machining does not thermally damage the workpiece or appear to introduce significant levels of residual stress, which is important for the survival of brittle materials in service. The

  3. Find the Simple Machines

    NSDL National Science Digital Library

    2012-07-17

    This is a web activity about simple machines. Learners will explore a lawn mower and identify six different simple machines which work together to help make our lives easier. This is an excellent activity for exploring how simple machines, and science in general, apply to learners' everyday lives.

  4. Machine tool locator

    DOEpatents

    Hanlon, John A. (Los Alamos, NM); Gill, Timothy J. (Stanley, NM)

    2001-01-01

    Machine tools can be accurately measured and positioned on manufacturing machines within very small tolerances by use of an autocollimator on a 3-axis mount on a manufacturing machine and positioned so as to focus on a reference tooling ball or a machine tool, a digital camera connected to the viewing end of the autocollimator, and a marker and measure generator for receiving digital images from the camera, then displaying or measuring distances between the projection reticle and the reference reticle on the monitoring screen, and relating the distances to the actual position of the autocollimator relative to the reference tooling ball. The images and measurements are used to set the position of the machine tool and to measure the size and shape of the machine tool tip, and examine cutting edge wear. patent

  5. Fault Tolerant State Machines

    NASA Technical Reports Server (NTRS)

    Burke, Gary R.; Taft, Stephanie

    2004-01-01

    State machines are commonly used to control sequential logic in FPGAs and ASKS. An errant state machine can cause considerable damage to the device it is controlling. For example in space applications, the FPGA might be controlling Pyros, which when fired at the wrong time will cause a mission failure. Even a well designed state machine can be subject to random errors us a result of SEUs from the radiation environment in space. There are various ways to encode the states of a state machine, and the type of encoding makes a large difference in the susceptibility of the state machine to radiation. In this paper we compare 4 methods of state machine encoding and find which method gives the best fault tolerance, as well as determining the resources needed for each method.

  6. Quantum Learning Machine

    E-print Network

    Jeongho Bang; James Lim; M. S. Kim; Jinhyoung Lee

    2008-03-31

    We propose a novel notion of a quantum learning machine for automatically controlling quantum coherence and for developing quantum algorithms. A quantum learning machine can be trained to learn a certain task with no a priori knowledge on its algorithm. As an example, it is demonstrated that the quantum learning machine learns Deutsch's task and finds itself a quantum algorithm, that is different from but equivalent to the original one.

  7. Bike machine energy education

    Microsoft Academic Search

    Sanford Jay Rotter; James Lee Ravenscroft; Raul Gonzalez

    2010-01-01

    A bike-powered machine offers physical kinesthetic learning and play. This is equivalent to past generation's playing with Erector Sets to building Heathkits [1], [2]. The excitement of riding a bike machine offers a different path to learning that turns a short-term memory into a long-term memory. Bike machines provide energy education to the public in order for them to understand

  8. Machine Learning and Agents

    Microsoft Academic Search

    Piotr J?drzejowicz

    \\u000a The paper reviews current research results integrating machine learning and agent technologies. Although complementary solutions\\u000a from both fields are discussed the focus is on using agent technology in the field of machine learning with a particular interest\\u000a on applying agent-based solutions to supervised learning. The paper contains a short review of applications, in which machine\\u000a learning methods have been used

  9. Perspex machine II: visualization

    NASA Astrophysics Data System (ADS)

    Anderson, James A. D. W.

    2004-12-01

    We review the perspex machine and improve it by reducing its halting conditions to one condition. We also introduce a data structure, called the "access column," that can accelerate a wide class of perspex programs. We show how the perspex can be visualised as a tetrahedron, artificial neuron, computer program, and as a geometrical transformation. We discuss the temporal properties of the perspex machine, dissolve the famous time travel paradox, and present a hypothetical time machine. Finally, we discuss some mental properties and show how the perspex machine solves the mind-body problem and, specifically, how it provides one physical explanation for the occurrence of paradigm shifts.

  10. Perspex machine II: visualization

    NASA Astrophysics Data System (ADS)

    Anderson, James A. D. W.

    2005-01-01

    We review the perspex machine and improve it by reducing its halting conditions to one condition. We also introduce a data structure, called the "access column," that can accelerate a wide class of perspex programs. We show how the perspex can be visualised as a tetrahedron, artificial neuron, computer program, and as a geometrical transformation. We discuss the temporal properties of the perspex machine, dissolve the famous time travel paradox, and present a hypothetical time machine. Finally, we discuss some mental properties and show how the perspex machine solves the mind-body problem and, specifically, how it provides one physical explanation for the occurrence of paradigm shifts.

  11. Chaotic Boltzmann machines.

    PubMed

    Suzuki, Hideyuki; Imura, Jun-ichi; Horio, Yoshihiko; Aihara, Kazuyuki

    2013-01-01

    The chaotic Boltzmann machine proposed in this paper is a chaotic pseudo-billiard system that works as a Boltzmann machine. Chaotic Boltzmann machines are shown numerically to have computing abilities comparable to conventional (stochastic) Boltzmann machines. Since no randomness is required, efficient hardware implementation is expected. Moreover, the ferromagnetic phase transition of the Ising model is shown to be characterised by the largest Lyapunov exponent of the proposed system. In general, a method to relate probabilistic models to nonlinear dynamics by derandomising Gibbs sampling is presented. PMID:23558425

  12. Parallel Kinematic Machines (PKM)

    SciTech Connect

    Henry, R.S.

    2000-03-17

    The purpose of this 3-year cooperative research project was to develop a parallel kinematic machining (PKM) capability for complex parts that normally require expensive multiple setups on conventional orthogonal machine tools. This non-conventional, non-orthogonal machining approach is based on a 6-axis positioning system commonly referred to as a hexapod. Sandia National Laboratories/New Mexico (SNL/NM) was the lead site responsible for a multitude of projects that defined the machining parameters and detailed the metrology of the hexapod. The role of the Kansas City Plant (KCP) in this project was limited to evaluating the application of this unique technology to production applications.

  13. On-Machine Acceptance

    SciTech Connect

    Arnold, K.F.

    2000-02-14

    Probing processes are used intermittently and not effectively as an on-line measurement device. This project was needed to evolve machine probing from merely a setup aid to an on-the-machine inspection system. Use of probing for on-machine inspection would significantly decrease cycle time by elimination of the need for first-piece inspection (at a remote location). Federal Manufacturing and Technologies (FM and T) had the manufacturing facility and the ability to integrate the system into production. The Contractor had a system that could optimize the machine tool to compensate for thermal growth and related error.

  14. Hybrid machining of Inconel 718

    Microsoft Academic Search

    Z. Y Wang; K. P Rajurkar; J Fan; S Lei; Y. C Shin; G Petrescu

    2003-01-01

    A new approach for machining of Inconel 718 is presented in this paper. It combines traditional turning with cryogenically enhanced machining and plasma enhanced machining. Cryogenically enhanced machining is used to reduce the temperatures in the cutting tool, and thus reduces temperature-dependent tool wear to prolong tool life, whereas plasma enhanced machining is used to increase the temperatures in the

  15. 14. Interior, Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Interior, Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific Railroad Carlin Shops, view to north (90mm lens). - Southern Pacific Railroad, Carlin Shops, Roundhouse Machine Shop Extension, Foot of Sixth Street, Carlin, Elko County, NV

  16. BRITISH MOLDING MACHINE, PBQ AUTOMATIC COPE AND DRAG MOLDING MACHINE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    BRITISH MOLDING MACHINE, PBQ AUTOMATIC COPE AND DRAG MOLDING MACHINE MAKES BOTH MOLD HALVES INDIVIDUALLY WHICH ARE LATER ROTATED, ASSEMBLED, AND LOWERED TO POURING CONVEYORS BY ASSISTING MACHINES. - Southern Ductile Casting Company, Casting, 2217 Carolina Avenue, Bessemer, Jefferson County, AL

  17. Drum cutter mining machine

    SciTech Connect

    Oberste-beulmann, K.; Schupphaus, H.

    1980-02-19

    A drum cutter mining machine includes a machine frame with a winch having a drive wheel to engage a rack or chain which extends along the path of travel by the mining machine to propel the machine along a mine face. The mining machine is made up of discrete units which include a machine body and machine housings joined to opposite sides of the machine body. The winch is either coupled through a drive train with a feed drive motor or coupled to the drive motor for cutter drums. The machine housings each support a pivot shaft coupled by an arm to a drum cutter. One of these housings includes a removable end cover and a recess adapted to receive a support housing for a spur gear system used to transmit torque from a feed drive motor to a reduction gear system which is, in turn, coupled to the drive wheel of the winch. In one embodiment, a removable end cover on the machine housing provides access to the feed drive motor. The feed drive motor is arranged so that the rotational axis of its drive output shaft extends transversely to the stow side of the machine frame. In another embodiment, the reduction gear system is arranged at one side of the pivot shaft for the cutter drum while the drive motor therefor is arranged at the other side of the pivot shaft and coupled thereto through the spur gear system. In a further embodiment, the reduction gear system is disposed between the feed motor and the pivot shaft.

  18. Diamond machine tool face lapping machine

    DOEpatents

    Yetter, H.H.

    1985-05-06

    An apparatus for shaping, sharpening and polishing diamond-tipped single-point machine tools. The isolation of a rotating grinding wheel from its driving apparatus using an air bearing and causing the tool to be shaped, polished or sharpened to be moved across the surface of the grinding wheel so that it does not remain at one radius for more than a single rotation of the grinding wheel has been found to readily result in machine tools of a quality which can only be obtained by the most tedious and costly processing procedures, and previously unattainable by simple lapping techniques.

  19. Millikelvin Lab Machine Shop

    E-print Network

    McQuade, D. Tyler

    Millikelvin Lab OP105­112 Machine Shop OP132 Resistive Magnet Shop CICC Winding Area Transformers Transformers Part Shop OP128 Dock Control Room 45 T Physical Plant Helium Recovery System MagnetCells Shipping This building is home to the Millikelvin lab, the control room, the resistive magnet and machine shops, the CICC

  20. Precision laser machining program

    Microsoft Academic Search

    L. N. Durvasula

    2001-01-01

    High brightness, diode pumped solid state laser technology has now progressed to a point that it is envisioned as the next-generation industrial laser. In response, the Precision Laser Machining (PLM) Consortium was formed as part of the US Defense Advanced Research Project Agency (DARPA) Technology Reinvestment Project. The goal of PLM is to develop a new generation of laser machine

  1. Knowledge Based Machine Translation

    Microsoft Academic Search

    Ghulam Rasool Tahir; Sohail Asghar; Nayyer Masood

    2010-01-01

    Machine translation, a part of computational Linguistics, belongs to Natural Language Processing (NLP) and is a hot issue in the computational society. Gap between the linguist and the computer programmer, gives birth to so many problems like lexical ambiguity, syntactic and structural ambiguity, polysemy, induction, discourses, anaphoric ambiguity and different shade of meanings. Mostly English-to-Urdu machine translation systems were developed

  2. Machine Translation Project

    NASA Technical Reports Server (NTRS)

    Bajis, Katie

    1993-01-01

    The characteristics and capabilities of existing machine translation systems were examined and procurement recommendations were developed. Four systems, SYSTRAN, GLOBALINK, PC TRANSLATOR, and STYLUS, were determined to meet the NASA requirements for a machine translation system. Initially, four language pairs were selected for implementation. These are Russian-English, French-English, German-English, and Japanese-English.

  3. The Set Covering Machine

    Microsoft Academic Search

    Mario Marchand; John Shawe-taylor

    2002-01-01

    We extend the classical algorithms of Valiant and Haussler for learning compact conjunc- tions and disjunctions of Boolean attributes to allow features that are constructed from the data and to allow a trade-off between accuracy and complexity. The result is a general- purpose learning machine, suitable for practical learning tasks, that we call the set covering machine. We present a

  4. Infinite Time Turing Machines

    Microsoft Academic Search

    Joel David Hamkins; Andy Lewis

    2000-01-01

    We extend in a natural way the operation of Turing machines to infinite ordinal time, and investigate the resulting supertask theory of computability and decidability on the reals. Every ?11 set, for example, is decidable by such machines, and the semi-decidable sets form a portion of the ?12 sets. Our oracle concept leads to a notion of relative computability for

  5. Secondary Masters in Machine Learning

    E-print Network

    Page 1 Secondary Masters in Machine Learning Student Handbook Revised 8/20/14 #12;Page 2 Table:.......................................................................................8 Machine Learning Journal Club.........................................................................................................11 #12;Page 3 Introduction The field of machine learning is concerned with the question of how

  6. The KANTOO Machine Translation Environment

    E-print Network

    Shamos, Michael I.

    machine translation system. 1 Introduction KANTOO is a knowledge­based, interlingual machine translation Server Knowledge Bases Lexical Maintenance Tool Language Translation Database Oracle DB Oracle DB KANTOOThe KANTOO Machine Translation Environment Eric Nyberg and Teruko Mitamura Language Technologies

  7. Introduction to machine learning.

    PubMed

    Ba?tanlar, Yalin; Ozuysal, Mustafa

    2014-01-01

    The machine learning field, which can be briefly defined as enabling computers make successful predictions using past experiences, has exhibited an impressive development recently with the help of the rapid increase in the storage capacity and processing power of computers. Together with many other disciplines, machine learning methods have been widely employed in bioinformatics. The difficulties and cost of biological analyses have led to the development of sophisticated machine learning approaches for this application area. In this chapter, we first review the fundamental concepts of machine learning such as feature assessment, unsupervised versus supervised learning and types of classification. Then, we point out the main issues of designing machine learning experiments and their performance evaluation. Finally, we introduce some supervised learning methods. PMID:24272434

  8. Machine LearningMachine Learning Stephen Scott

    E-print Network

    Scott, Stephen D.

    that automatically learn from experience ­ Important research goal of artificial intelligence (Very) small sampling vs. non-trucks Examples are described by features ­ E.g. number-of-wheels (integer), relative-height (height divided by width), hauls-cargo (yes/no) A machine learning algorithm uses these examples to create

  9. Machine Learning and Radiology

    PubMed Central

    Wang, Shijun; Summers, Ronald M.

    2012-01-01

    In this paper, we give a short introduction to machine learning and survey its applications in radiology. We focused on six categories of applications in radiology: medical image segmentation, registration, computer aided detection and diagnosis, brain function or activity analysis and neurological disease diagnosis from fMR images, content-based image retrieval systems for CT or MRI images, and text analysis of radiology reports using natural language processing (NLP) and natural language understanding (NLU). This survey shows that machine learning plays a key role in many radiology applications. Machine learning identifies complex patterns automatically and helps radiologists make intelligent decisions on radiology data such as conventional radiographs, CT, MRI, and PET images and radiology reports. In many applications, the performance of machine learning-based automatic detection and diagnosis systems has shown to be comparable to that of a well-trained and experienced radiologist. Technology development in machine learning and radiology will benefit from each other in the long run. Key contributions and common characteristics of machine learning techniques in radiology are discussed. We also discuss the problem of translating machine learning applications to the radiology clinical setting, including advantages and potential barriers. PMID:22465077

  10. Machine Tool Software

    NASA Technical Reports Server (NTRS)

    1988-01-01

    A NASA-developed software package has played a part in technical education of students who major in Mechanical Engineering Technology at William Rainey Harper College. Professor Hack has been using (APT) Automatically Programmed Tool Software since 1969 in his CAD/CAM Computer Aided Design and Manufacturing curriculum. Professor Hack teaches the use of APT programming languages for control of metal cutting machines. Machine tool instructions are geometry definitions written in APT Language to constitute a "part program." The part program is processed by the machine tool. CAD/CAM students go from writing a program to cutting steel in the course of a semester.

  11. Virtual Turing Machine 2

    NSDL National Science Digital Library

    Paul R. C. Ming

    A Turing machine is theoretical computer consisting of a finite set of internal states, a finite alphabet that includes a blank symbol, and a finite set of instructions. It has a physical head and a physical infinitely long tape, which is divided into cells. The cell values consist of the alphabet. The tape has a finite number of non-blank cells. The head can read and write to the cells and move the tape one cell to the left and one cell to the right. The Virtual Turing Machine lets you input tape values and an instruction set to see the output of a turing machine.

  12. 16. Interior, Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. Interior, Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific Railroad Carlin Shops, view to south (90mm lens). Note the large segmental-arched doorway to move locomotives in and out of Machine Shop. - Southern Pacific Railroad, Carlin Shops, Roundhouse Machine Shop Extension, Foot of Sixth Street, Carlin, Elko County, NV

  13. Speech Recognition in Machines 785 Speech Recognition in Machines

    E-print Network

    Liebling, Michael

    Speech Recognition in Machines 785 Speech Recognition in Machines Over the past several decades (speech recognition systems) human speech. We concentrate on speech recognition systems in this section. Speech recognition by machine refers to the capability of a machine to convert human speech to a textual

  14. Why Machine Learning and Games? Machine Learning in Video Games

    E-print Network

    Hunt, Galen

    #12;Why Machine Learning and Games? Machine Learning in Video Games DrivatarsTM Reinforcement Learning Machine Learning in Online Games TrueSkillTM Halo 3 The Path of Go Conclusions #12;Test Beds for Machine Learning · Perfect instrumentation and measurements · Perfect control and manipulation · Reduced

  15. Positive Linear Function Machine

    NSDL National Science Digital Library

    Students investigate linear functions with positive slopes by trying to guess the slope and intercept from inputs and outputs. Positive Linear Function Machine is one of the Interactivate assessment explorers.

  16. Machine Translation for Twitter 

    E-print Network

    Jehl, Laura Elisabeth

    2010-11-24

    We carried out a study in which we explored the feasibility of machine translation for Twitter for the language pair English and German. As a first step we created a small bilingual corpus of 1,000 tweets. Using this ...

  17. Microcircuit-cleaning machine

    NASA Technical Reports Server (NTRS)

    Robinson, W. W.; Williamson, J. C.

    1978-01-01

    Circuit shaker removes loose particles from hybrid microcircuit packages. Machine can reduce rejections from particle impact noise determination (PIND) tests to less than 7 percent. Shaker is easily constructed and could be manufactured for distribution as kit.

  18. Molecular Machines: Nanoscale gadgets

    NASA Astrophysics Data System (ADS)

    Garcia-Garibay, Miguel A.

    2008-06-01

    Meeting their biological counterparts halfway, artificial molecular machines embedded in liquid crystals, crystalline solids and mesoporous materials are poised to meet the demands of the next generation of functional materials.

  19. Protein Thin Film Machines

    E-print Network

    Federici, Stefania

    We report the first example of microcantilever beams that are reversibly driven by protein thin film machines fuelled by cycling the salt concentration of the surrounding solution. We also show that upon the same salinity ...

  20. Metalworking and machining fluids

    DOEpatents

    Erdemir, Ali (Naperville, IL); Sykora, Frank (Caledon, ON, CA); Dorbeck, Mark (Brighton, MI)

    2010-10-12

    Improved boron-based metal working and machining fluids. Boric acid and boron-based additives that, when mixed with certain carrier fluids, such as water, cellulose and/or cellulose derivatives, polyhydric alcohol, polyalkylene glycol, polyvinyl alcohol, starch, dextrin, in solid and/or solvated forms result in improved metalworking and machining of metallic work pieces. Fluids manufactured with boric acid or boron-based additives effectively reduce friction, prevent galling and severe wear problems on cutting and forming tools.

  1. The Lisp Machine manual

    Microsoft Academic Search

    Daniel Weinreb; David Moon

    1981-01-01

    This 471-page, softcover manual describes the programming language and software environment of the Lisp Machine developed at M.I.T.'s Artificial Intelligence Laboratory over the past 8 years. The Lisp Machine is the result of a successful experiment in computer science: a distributed computing system consisting of a network of powerful 32-bit personal computers, implemented with custom hardware and software as complete,

  2. A Function Machine

    ERIC Educational Resources Information Center

    Hewitt, Dave

    2008-01-01

    In this article, the author describes a lesson he observed involving a function machine. This function machine was a box with a slot at the top of one side and a large cut-out hole at the bottom of the opposite side. A card with a number written on it (the input) was pushed into the slot and the teacher put their hand through the hole of the other…

  3. Human-machine interactions

    DOEpatents

    Forsythe, J. Chris (Sandia Park, NM); Xavier, Patrick G. (Albuquerque, NM); Abbott, Robert G. (Albuquerque, NM); Brannon, Nathan G. (Albuquerque, NM); Bernard, Michael L. (Tijeras, NM); Speed, Ann E. (Albuquerque, NM)

    2009-04-28

    Digital technology utilizing a cognitive model based on human naturalistic decision-making processes, including pattern recognition and episodic memory, can reduce the dependency of human-machine interactions on the abilities of a human user and can enable a machine to more closely emulate human-like responses. Such a cognitive model can enable digital technology to use cognitive capacities fundamental to human-like communication and cooperation to interact with humans.

  4. Machine Instruction Count Program

    Microsoft Academic Search

    John E. Gaffney Jr.

    1982-01-01

    The Machine Instruction Count Program (MIC Program) was originally developed in 1978 to produce 'operator' and 'operand' counts of object programs written for the AN\\/UYK-7 military computer. In 1981, its capability was expanded so that it could apply to the AN\\/UYS-1 (or “Advanced Signal Processor”) military computer. The former machine, made by UNIVAC, hosts the IBM-developed software for the sonar

  5. Pavement Recycling Machine 

    E-print Network

    Raiford Stripling Associates, Inc.; Stripling, Raiford L.

    2011-08-29

    APPLICATIONS OF ALGEBRA TO THE STRUCTURE THEORY OP SEQUENTIAL MACHINES A Thesis by OSCAR GUNNAR BARRIENTOS ENRIQUEZ Submitted to the Graduate College of Texas A&M University in partial fulfillment of the requirement for the degree of MASTER... OF SCIENCE May 1975 Major Subject: Mathematics APPLICATIONS OF ALGEBRA TO THE STRUCTURE THEORY OF SEQUENTIAL MACHINES A Thesis by OSCAR GUNNAR BARRIENTOS ENRIQUEZ Approved as to style and content by: (Chairman o Committee) (Head of Department...

  6. Machine Learning Thomas G. Dietterich

    E-print Network

    Machine Learning Thomas G. Dietterich Department of Computer Science Oregon State University Corvallis, OR 97331 1 Introduction Machine Learning is the study of methods for programming computers a computer system. A machine learning system can study recorded data and subsequent machine failures

  7. Interactive Machine Learning Mustafa Bilgic

    E-print Network

    Heller, Barbara

    Interactive Machine Learning Mustafa Bilgic "Who We Are" Seminars IIT 9/24/2013 #12;Bio Bachelor Komurlu 2 #12;Research Interests Machine learning Interactive machine learning Statistical relational Diagnosis Recommender Systems Search Engines 4 #12;How Does a Machine Learn? There are many approaches

  8. Machining strategy choice: performance VIEWER

    Microsoft Academic Search

    Laurent Tapie; Kwamivi Bernardin Mawussi; Bernard Anselmetti

    2009-01-01

    Nowadays high speed machining (HSM) machine tool combines productivity and part quality. So mould and die maker invested in HSM. Die and mould features are more and more complex shaped. Thus, it is difficult to choose the best machining strategy according to part shape. Geometrical analysis of machining features is not sufficient to make an optimal choice. Some research show

  9. Enhanced virtual machining for sculptured surfaces by integrating machine tool error models into NC machining simulation

    Microsoft Academic Search

    Yizhen Lin; Yin-Lin Shen

    2004-01-01

    Sculptured surface machining is a time-consuming and costly process. It requires simultaneously controlled motion of the machine axes. However, positioning inaccuracies or errors exist in machine tools. The combination of error motions of the machine axes will result in a complicated pattern of part geometry errors. In order to quantitatively predict these part geometry errors, a new application framework ‘enhanced

  10. The Bearingless Electrical Machine

    NASA Technical Reports Server (NTRS)

    Bichsel, J.

    1992-01-01

    Electromagnetic bearings allow the suspension of solids. For rotary applications, the most important physical effect is the force of a magnetic circuit to a high permeable armature, called the MAXWELL force. Contrary to the commonly used MAXWELL bearings, the bearingless electrical machine will take advantage of the reaction force of a conductor carrying a current in a magnetic field. This kind of force, called Lorentz force, generates the torque in direct current, asynchronous and synchronous machines. The magnetic field, which already exists in electrical machines and helps to build up the torque, can also be used for the suspension of the rotor. Besides the normal winding of the stator, a special winding was added, which generates forces for levitation. So a radial bearing, which is integrated directly in the active part of the machine, and the motor use the laminated core simultaneously. The winding was constructed for the levitating forces in a special way so that commercially available standard ac inverters for drives can be used. Besides wholly magnetic suspended machines, there is a wide range of applications for normal drives with ball bearings. Resonances of the rotor, especially critical speeds, can be damped actively.

  11. Micro-machined resonator

    DOEpatents

    Godshall, N.A.; Koehler, D.R.; Liang, A.Y.; Smith, B.K.

    1993-03-30

    A micro-machined resonator, typically quartz, with upper and lower micro-machinable support members, or covers, having etched wells which may be lined with conductive electrode material, between the support members is a quartz resonator having an energy trapping quartz mesa capacitively coupled to the electrode through a diaphragm; the quartz resonator is supported by either micro-machined cantilever springs or by thin layers extending over the surfaces of the support. If the diaphragm is rigid, clock applications are available, and if the diaphragm is resilient, then transducer applications can be achieved. Either the thin support layers or the conductive electrode material can be integral with the diaphragm. In any event, the covers are bonded to form a hermetic seal and the interior volume may be filled with a gas or may be evacuated. In addition, one or both of the covers may include oscillator and interface circuitry for the resonator.

  12. Constructing Time Machines

    E-print Network

    G. M. Shore

    2002-10-15

    The existence of time machines, understood as spacetime constructions exhibiting physically realised closed timelike curves (CTCs), would raise fundamental problems with causality and challenge our current understanding of classical and quantum theories of gravity. In this paper, we investigate three proposals for time machines which share some common features: cosmic strings in relative motion, where the conical spacetime appears to allow CTCs; colliding gravitational shock waves, which in Aichelburg-Sexl coordinates imply discontinuous geodesics; and the superluminal propagation of light in gravitational radiation metrics in a modified electrodynamics featuring violations of the strong equivalence principle. While we show that ultimately none of these constructions creates a working time machine, their study illustrates the subtle levels at which causal self-consistency imposes itself, and we consider what intuition can be drawn from these examples for future theories.

  13. Precision Robotic Assembly Machine

    ScienceCinema

    None

    2010-09-01

    The world's largest laser system is the National Ignition Facility (NIF), located at Lawrence Livermore National Laboratory. NIF's 192 laser beams are amplified to extremely high energy, and then focused onto a tiny target about the size of a BB, containing frozen hydrogen gas. The target must be perfectly machined to incredibly demanding specifications. The Laboratory's scientists and engineers have developed a device called the "Precision Robotic Assembly Machine" for this purpose. Its unique design won a prestigious R&D-100 award from R&D Magazine.

  14. Man - Machine Communication

    E-print Network

    Petersen, Peter; Nielsen, Henning

    1984-01-01

    This report describes a Man-to-Machine Communication module which together with a STAC can take care of all operator inputs from the touch-screen, tracker balls and mechanical buttons. The MMC module can also contain a G64 card which could be a GPIB driver but many other G64 cards could be used. The soft-ware services the input devices and makes the results accessible from the CAMAC bus. NODAL functions for the Man Machine Communication is implemented in the STAC and in the ICC.

  15. Refrigerating machine oil

    SciTech Connect

    Nozawa, K.

    1981-03-17

    Refrigerating machine oil to be filled in a sealed motorcompressor unit constituting a refrigerating cycle system including an electric refrigerator, an electric cold-storage box, a small-scaled electric refrigerating show-case, a small-scaled electric cold-storage show-case and the like, is arranged to have a specifically enhanced property, in which smaller initial driving power consumption of the sealed motor-compressor and easier supply of the predetermined amount of the refrigerating machine oil to the refrigerating system are both guaranteed even in a rather low environmental temperature condition.

  16. 14. Machine in north 1922 section of Building 59. Machine ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Machine in north 1922 section of Building 59. Machine is 24' Jointer made by Oliver Machinery Co. Camera pointed E. - Puget Sound Naval Shipyard, Pattern Shop, Farragut Avenue, Bremerton, Kitsap County, WA

  17. Tool allocation and machining conditions optimization for CNC machines

    Microsoft Academic Search

    M. Selim Akturk; Selcuk Avci

    1996-01-01

    In the literature, there exist many variations of machining economics problem in terms of modelling approaches and solution methodologies. However most of the existing studies focus on the single machining operation which is seldom in practice. On the other hand, tool management approaches at the system level fail to relate the tooling issues to the machining conditions, and ignore the

  18. Portable Fatigue-Testing Machine

    NASA Technical Reports Server (NTRS)

    Lewis, J.; Daugherty, C.

    1984-01-01

    Portable machine constructed for fatigue testing of structural materials or machinery parts subjected to fatigue loads. Piezoelectric crystal stack adds oscillatory force to constant force. Machine tests wider variety of objects than with usual rotating-beam fatigue tests.

  19. Development of Electrochemical Micro Machining 

    E-print Network

    Srinivas Sundarram, Sriharsha

    2008-10-10

    in demanding applications like aerospace and biomedical industries. Micro electrochemical machining (?ECM) removes material while holding micron tolerances and ?ECM can machine hard metals and alloys. This study aims at developing a novel ?ECM utilizing high...

  20. Support vector machines

    NASA Technical Reports Server (NTRS)

    Garay, Michael J.; Mazzoni, Dominic; Davies, Roger; Wagstaff, Kiri

    2004-01-01

    Support Vector Machines (SVMs) are a type of supervised learning algorith,, other examples of which are Artificial Neural Networks (ANNs), Decision Trees, and Naive Bayesian Classifiers. Supervised learning algorithms are used to classify objects labled by a 'supervisor' - typically a human 'expert.'.

  1. Machine-Aided Indexing.

    ERIC Educational Resources Information Center

    Jacobs, Charles R.

    Progress is reported at the 1,000,000 word level on the development of a partial syntatic analysis technique for indexing text. A new indexing subroutine for hyphens is provided. New grammars written and programmed for Machine Aided Indexing (MAI) are discussed. (ED 069 290 is a related document) (Author)

  2. The Variable Machine

    NSDL National Science Digital Library

    National Council of Teachers of Mathematics

    2008-01-01

    This math lesson provides an introduction to the use of variables, and develops learners' algebraic thinking. Learners create "variable machines" out of paper to discover the "value" of words like their first and last names. Learners explore which words have even or odd values and which words have the largest value. This lesson guide includes questions for learners, extensions, and reflection questions.

  3. Lecture 13: Kernel Machines

    E-print Network

    Roweis, Sam

    (x1, x2) called a kernel. · This has a very deep interpretation as mapping the data into a much higherLecture 13: Kernel Machines Sam Roweis December 2, 2003 Algorithms Based on Vector Data · Recall our normal approach to many classification, regression, and unsupervised learning problems: Embed

  4. Deep Boltzmann Machines

    Microsoft Academic Search

    Ruslan Salakhutdinov; Geoffrey E. Hinton

    2009-01-01

    We present a new learning algorithm for Boltz- mann machines that contain many layers of hid- den variables. Data-dependent expectations are estimated using a variational approximation that tends to focus on a single mode, and data- independent expectations are approximated us- ing persistent Markov chains. The use of two quite different techniques for estimating the two types of expectation that

  5. Operating the Lisp Machine

    E-print Network

    Moon, David A.

    This document is a draft copy of a portion of the Lisp Machine window system manual. It is being published in this form now to make it available, since the complete window system manual is unlikely to be finished in the ...

  6. Optimizing Embedded Virtual Machines

    Microsoft Academic Search

    Joel Koshy; Raju Pandey; Ingwar Wirjawan

    2009-01-01

    Virtual machines (VMs) play an important role in mainstream computing by enabling interoperability, security, and higher levels of abstraction. Their use in embedded computing systems is deterred primarily by the resource constraints of embedded microcontrollers. In this paper, we show how various optimizations can significantly decrease these overheads, making VMs viable as system software for even low-end (8- or 16-bit)

  7. Machine Parts as Metaphor.

    ERIC Educational Resources Information Center

    Porter, Gerald

    The connection between Language for Specific Purposes (LSP) and literature is discussed with examples of technical vocabulary drawn from a variety of writers, with particular attention to a sketch by the British dramatist Harold Pinter, "Trouble in the Works," which makes extensive use of the terminology of machine parts. It is noted that within…

  8. The Art Machine.

    ERIC Educational Resources Information Center

    Vertelney, Harry; Grossberger, Lucia

    1983-01-01

    Introduces educators to possibilities of computer graphics using an inexpensive computer system which takes advantage of existing equipment (35mm camera, super 8 movie camera, VHS video cassette recorder). The concept of the "art machine" is explained, highlighting input and output devices (X-Y plotter, graphic tablets, video digitizers). (EJS)

  9. Machine Checked Conditional Information

    E-print Network

    Singh, Jaswinder Pal

    1 Machine Checked Conditional Information Flow Joey Dodds, Andrew Appel (Advisor) Collaborators State University) To appear in POST 2012 #12;2 Outline 1.What is Information flow? 2.SPARK programming 1.What is Information flow? 2.SPARK programming language 3.Agreement Logic 4.SIFL Static Analyzer 5

  10. The virtual time machine

    Microsoft Academic Search

    Richard M. Fujimoto

    1989-01-01

    A parallel computer architecture is proposed that is based on an optimistic style of execution. Specifically, the Virtual Time Machine (VTM) detects violations of data depen- dence constraints at runtime, and automatically recovers from them. In order to efficiently implement this mecha- nism, a sophisticated, two-dimensional memory system is proposed that is addressed using both a spatial and a tern.

  11. Sculptured Surface Machining University of New Hampshire

    E-print Network

    New Hampshire, University of

    Sculptured Surface Machining University of New Hampshire · Personnel ­ Robert B. Jerard & Barry K) Fast Verification #12;University of New Hampshire - Sculptured Surface Machining Surface "Fairness;University of New Hampshire - Sculptured Surface Machining "Virtual Machining" Realistic simulations show

  12. The Fusion Machine (extended abstract)

    E-print Network

    Gardner, Philippa

    The Fusion Machine (extended abstract) Philippa Gardner Cosimo Laneve Lucian Wischik March 27, 2002. In particular, we describe a dis- tributed abstract machine called the fusion machine. In it, only channels exist at runtime. It uses a form of concurrent constraints called fusions--equations on channel names

  13. Machine Learning Thomas G. Dietterich

    E-print Network

    Bylander, Tom

    Machine Learning Thomas G. Dietterich Department of Computer Science Oregon State University Corvallis, OR 97331 1 Introduction Machine Learning is the study of methods for programming computers necessary to build a computer system. A machine learning system can study recorded data and subsequent

  14. Audio-Visual Teaching Machines.

    ERIC Educational Resources Information Center

    Dorsett, Loyd G.

    An audiovisual teaching machine (AVTM) presents programed audio and visual material simultaneously to a student and accepts his response. If his response is correct, the machine proceeds with the lesson; if it is incorrect, the machine so indicates and permits another choice (linear) or automatically presents supplementary material (branching).…

  15. Toward Machines with Emotional Intelligence

    E-print Network

    1 Toward Machines with Emotional Intelligence Rosalind W. Picard MIT Media Laboratory Abstract pets, desktop computers, and more) skills of emotional intelligence. Machines have long been able intelligent. Machines are now being given the ability to sense and recognize expressions of human emotion

  16. Machine Learning: CS 6375 Introduction

    E-print Network

    Gogate, Vibhav

    rankings today are mostly a matter of machine learning" (Prabhakar Raghavan, Dir. Research, YahooMachine Learning: CS 6375 Introduction Instructor: Vibhav Gogate The University of Texas at Dallas (75 to 79), B- (70 to 74), Fail (69 and below). #12;Source Materials · T. Mitchell, Machine Learning

  17. Hanghang Tong Machine Learning Department

    E-print Network

    Hanghang Tong Machine Learning Department School of Computer Science Carnegie Mellon University@cs.cmu.edu Homepage: www.cs.cmu.edu/~htong Education 9/2008-11/2009 Ph.D in Machine Learning Department, School. in Machine Learning Department, School of Computer Science, Carnegie Mellon University (Advisor: Prof

  18. Hydraulic Fatigue-Testing Machine

    NASA Technical Reports Server (NTRS)

    Hodo, James D.; Moore, Dennis R.; Morris, Thomas F.; Tiller, Newton G.

    1987-01-01

    Fatigue-testing machine applies fluctuating tension to number of specimens at same time. When sample breaks, machine continues to test remaining specimens. Series of tensile tests needed to determine fatigue properties of materials performed more rapidly than in conventional fatigue-testing machine.

  19. TIME COMPLEXITY OF TURING MACHINES

    E-print Network

    Grigoriev, Dima

    TIME COMPLEXITY OF TURING MACHINES D. Yu. Grigor'ev MULTIDIMENSIONAL UDC 510.52 It is proved that the work of an indeterminate m-dimensional Turing machine with time com- plexity t can be simulated on an indeterminate k-dimensional (k -machine with time complexity t 1-(~/m)+(l/k)+e ffor any e > 0

  20. Lightning Protection for Rotating Machines

    Microsoft Academic Search

    G. D. McCann; E. Beck; L. A. Finzi

    1944-01-01

    The high monetary value and low insulation levels of rotating machines make it necessary to employ special protection. A rotating machine can be conceived as a transmission line with distributed constants, the essential difference being that the machine winding is wound back on itself in the form of turns, which may permit high voltage across the turn-to-turn insulation. The installation

  1. Simple Machines/Forces and Motion

    NSDL National Science Digital Library

    Miss B

    2011-11-04

    These are a list of links and activities about simple machines and forces and motion. To get the username and password for Pioneer Library talk to your local librarian. SIMPLE MACHINES ACTIVITIES Simple Machines (BrainPopJr)- This has a video about simple machines and activities as well. For some interactive activities about simple machines I really like these sites Simple Machines and Compound Machines (EdHeads), Simple Machines (MSI), and Learning Games for Kids. When you combine two or more simple machines you get compound machines, to look more into those go to The Compound Machine (EdHeads). To ...

  2. A Boltzmann machine for the organization of intelligent machines

    NASA Technical Reports Server (NTRS)

    Moed, Michael C.; Saridis, George N.

    1989-01-01

    In the present technological society, there is a major need to build machines that would execute intelligent tasks operating in uncertain environments with minimum interaction with a human operator. Although some designers have built smart robots, utilizing heuristic ideas, there is no systematic approach to design such machines in an engineering manner. Recently, cross-disciplinary research from the fields of computers, systems AI and information theory has served to set the foundations of the emerging area of the design of intelligent machines. Since 1977 Saridis has been developing an approach, defined as Hierarchical Intelligent Control, designed to organize, coordinate and execute anthropomorphic tasks by a machine with minimum interaction with a human operator. This approach utilizes analytical (probabilistic) models to describe and control the various functions of the intelligent machine structured by the intuitively defined principle of Increasing Precision with Decreasing Intelligence (IPDI) (Saridis 1979). This principle, even though resembles the managerial structure of organizational systems (Levis 1988), has been derived on an analytic basis by Saridis (1988). The purpose is to derive analytically a Boltzmann machine suitable for optimal connection of nodes in a neural net (Fahlman, Hinton, Sejnowski, 1985). Then this machine will serve to search for the optimal design of the organization level of an intelligent machine. In order to accomplish this, some mathematical theory of the intelligent machines will be first outlined. Then some definitions of the variables associated with the principle, like machine intelligence, machine knowledge, and precision will be made (Saridis, Valavanis 1988). Then a procedure to establish the Boltzmann machine on an analytic basis will be presented and illustrated by an example in designing the organization level of an Intelligent Machine. A new search technique, the Modified Genetic Algorithm, is presented and proved to converge to the minimum of a cost function. Finally, simulations will show the effectiveness of a variety of search techniques for the intelligent machine.

  3. CNC electrical discharge machining centers

    SciTech Connect

    Jaggars, S.R.

    1991-10-01

    Computer numerical control (CNC) electrical discharge machining (EDM) centers were investigated to evaluate the application and cost effectiveness of establishing this capability at Allied-Signal Inc., Kansas City Division (KCD). In line with this investigation, metal samples were designed, prepared, and machined on an existing 15-year-old EDM machine and on two current technology CNC EDM machining centers at outside vendors. The results were recorded and evaluated. The study revealed that CNC EDM centers are a capability that should be established at KCD. From the information gained, a machine specification was written and a shop was purchased and installed in the Engineering Shop. The older machine was exchanged for a new model. Additional machines were installed in the Tool Design and Fabrication and Precision Microfinishing departments. The Engineering Shop machine will be principally used for the following purposes: producing deep cavities in small corner radii, machining simulated casting models, machining difficult-to-machine materials, and polishing difficult-to-hand polish mold cavities. 2 refs., 18 figs., 3 tabs.

  4. Ecosystems, Organisms, and Machines

    NSDL National Science Digital Library

    EVELYN FOX KELLER (; )

    2005-12-01

    This peer reviewed article from Bioscience is about is the concept, and the term, "self-organization." The history of this term, originally introduced by Immanuel Kant to characterize the unique properties of living organisms, is inseparable from the history of biology. Only in the second half of the 20th century does it begin to acquire the promise of a physicalistic understanding. This it does with two critical transformations in the meaning of the term: first, with the advent of cybernetics and its dissolution of the boundary between organisms and machines, and second, with the mathematical triumphs of nonlinear dynamical systems theory and accompanying claims to having dissolved the boundary between organisms and such physical phenomena as thunderstorms. How do these transformations affect the applicability of self-organization to the ecosystem--that provocatively hybrid entity that is part organism, part machine, and perhaps even part thunderstorm?

  5. Checking the anaesthetic machine.

    PubMed

    Wicker, Paul; Smith, Brian

    2006-12-01

    Making sure that anaesthetic equipment is working correctly is an essential part of the anaesthetic practitioner's role. During induction of anaesthesia the patient is at one of the most vulnerable points in his or her perioperative care. This is the point at which equipment error may put the patient at high risk of harm, for example, through compromising the airway, causing circulatory problems, preventing satisfactory oxygenation or even causing death. Many writers have drawn comparisons between anaesthesia and aviation, with the suggestion that practitioners should check the anaesthetic machines using a 'cockpit drill' (Ranasinghe 2000). The purpose of this detailed check is to ensure the machine is safe to use. The careful attention to the check is a reflection of good practice which the practitioner's codes of professional practice demand (HPC 2004, NMC 2004). This article discusses the importance of following the anaesthetic checklist to the recommended standards for both the practitioner and the patient. PMID:17193997

  6. Checking anaesthetic machine.

    PubMed

    Wicker, Paul; Smith, Brian

    2008-08-01

    Making sure that anaesthetic equipment is working correctly is an essential part of the anaesthetic practitioner's role. During induction of anaesthesia the patient is at one of the most vulnerable points in his or her perioperative journey. This is the point at which equipment error may put the patient at high risk of harm, for example, through compromising the airway, causing circulatory problems, preventing satisfactory oxygenation or even causing death. Many writers have drawn comparisons between anaesthesia and aviation, with the suggestion that practitioners should check the anaesthetic machines using a 'cockpit drill' (Ranasinghe 2000). The purpose of this detailed check is to ensure the machine is safe to use. The careful attention to the check is a reflection of good practice which the practitioner's codes of professional practice demand (HPC 2004, NMC 2004). This article discusses the importance of following the anaesthetic checklist to the recommended standards for both the practitioner and the patient. PMID:18751494

  7. Laser tile machining process

    Microsoft Academic Search

    Lisa Bird

    1991-01-01

    A three-dimensional laser machining process is being developed to cut replacement tiles for the Space Shuttle. The process involves a carbon dioxide laser and a computer-controlled five-axis positioner. To date, successful straight-through cuts, curved-through cuts, and partial cuts have been made by the laser. Felt reusable surface insulation, another component of the Shuttle's thermal protection system, has also been successfully

  8. Bayes Point Machines

    Microsoft Academic Search

    Ralf Herbrich; Thore Graepel; Colin Campbell

    2001-01-01

    Kernel-classifiers comprise a powerful class of non-linear decision functions for binary classification. The support vector machine is an example of a learning algorithm for kernel classifiers that singles out the consistent classifier with the largest margin, i.e. minimal real-valued output on the training sample, within the set of consistent hypotheses, the so-called measure and leads to a steady decrease in

  9. Copying Machine Improvement

    NASA Technical Reports Server (NTRS)

    1981-01-01

    Manufacturer of the Model 2210 copying machine was looking for a plastic valve bushing material that could be produced by a low-cost injection molding process to replace the unsuitable valve bushing they were using. NERAC conducted a computer search of the NASA database and was able to supply Nashua Corporation with several technical reports in their area of interest. Information aided the company's development of a urethane valve bushing which solved the problem and created a dramatic reduction in unit cost.

  10. Development of reconfigurable machines

    Microsoft Academic Search

    Z. M. Bi; Sherman Y. T. Lang; M. Verner; P. Orban

    2008-01-01

    This paper summarizes our survey on the development of reconfigurable machines (RMs). The goals of this survey were to (i)\\u000a clarify the needs and drivers to develop the RMs, (ii) define the academic and practical issues involved in the development\\u000a of RMs, (iii) learn the state of the art of the R&D on design methodologies of the RMs, and (iv)

  11. Recurrent Support Vector Machines

    Microsoft Academic Search

    Matteo Gagliolo; Daan Wierstra; Faustino Gomez; IDSIA Galleria

    Abstract Existing Support Vector Machines (SVMs) need pre-wired finite time windo ws to predict and classify time series. They do not have an internal state necessary to deal with sequences involving arbitrary long-term dependencies. Here we introduce the first recurrent, truly s equential SVM-like devices with internal adaptive states, trained by a novel method called EVOlution of systems with KErnel-based

  12. Making molecular machines work.

    PubMed

    Browne, Wesley R; Feringa, Ben L

    2006-10-01

    In this review we chart recent advances in what is at once an old and very new field of endeavour--the achievement of control of motion at the molecular level including solid-state and surface-mounted rotors, and its natural progression to the development of synthetic molecular machines. Besides a discussion of design principles used to control linear and rotary motion in such molecular systems, this review will address the advances towards the construction of synthetic machines that can perform useful functions. Approaches taken by several research groups to construct wholly synthetic molecular machines and devices are compared. This will be illustrated with molecular rotors, elevators, valves, transporters, muscles and other motor functions used to develop smart materials. The demonstration of molecular machinery is highlighted through recent examples of systems capable of effecting macroscopic movement through concerted molecular motion. Several approaches to illustrate how molecular motor systems have been used to accomplish work are discussed. We will conclude with prospects for future developments in this exciting field of nanotechnology. PMID:18654138

  13. Superconducting and conventional machines

    NASA Astrophysics Data System (ADS)

    Campbell, A. M.

    2014-12-01

    A general comparison is made between conventional and superconducting machines using simple semi-quantitative arguments. A basic conventional machine with sinusoidal currents round rotor and stator is analysed analytically and expressions for the power per unit volume found. Typically about 50 MW per cubic metre of rotor can be obtained and the ratio of power to loss is approximatelythe square of the ratio of the diameter to the skin depth of copper. For a superconducting rotor the power depends on BJc which for YBCO is a maximum at 2 T. If this field could be achieved by the stator a superconducting rotor could be several orders of magnitude smaller than a conventional one. However this is very difficult to achieve. At 50 Hz AC losses are a major problem. Hysteresis losses depend on the ratio of the conductor thickness to the rotor radius so striating the conductor is desirable but low coupling losses requires a twist pitch significantly smaller than the penetration depth. The maximum power is proportional to the product of the rotor and stator currents and the main advantage of superconductors is their very high current density. Therefore the ultimate goal is to have both superconducting, but AC losses in the stator make this difficult. However replacing just the rotor conductors in a synchronous machine gives significant reductions in size and weight for a given power by increasing the electric loading.

  14. Architectures for intelligent machines

    NASA Technical Reports Server (NTRS)

    Saridis, George N.

    1991-01-01

    The theory of intelligent machines has been recently reformulated to incorporate new architectures that are using neural and Petri nets. The analytic functions of an intelligent machine are implemented by intelligent controls, using entropy as a measure. The resulting hierarchical control structure is based on the principle of increasing precision with decreasing intelligence. Each of the three levels of the intelligent control is using different architectures, in order to satisfy the requirements of the principle: the organization level is moduled after a Boltzmann machine for abstract reasoning, task planning and decision making; the coordination level is composed of a number of Petri net transducers supervised, for command exchange, by a dispatcher, which also serves as an interface to the organization level; the execution level, include the sensory, planning for navigation and control hardware which interacts one-to-one with the appropriate coordinators, while a VME bus provides a channel for database exchange among the several devices. This system is currently implemented on a robotic transporter, designed for space construction at the CIRSSE laboratories at the Rensselaer Polytechnic Institute. The progress of its development is reported.

  15. Making molecular machines work

    NASA Astrophysics Data System (ADS)

    Browne, Wesley R.; Feringa, Ben L.

    2006-10-01

    In this review we chart recent advances in what is at once an old and very new field of endeavour - the achievement of control of motion at the molecular level including solid-state and surface-mounted rotors, and its natural progression to the development of synthetic molecular machines. Besides a discussion of design principles used to control linear and rotary motion in such molecular systems, this review will address the advances towards the construction of synthetic machines that can perform useful functions. Approaches taken by several research groups to construct wholly synthetic molecular machines and devices are compared. This will be illustrated with molecular rotors, elevators, valves, transporters, muscles and other motor functions used to develop smart materials. The demonstration of molecular machinery is highlighted through recent examples of systems capable of effecting macroscopic movement through concerted molecular motion. Several approaches to illustrate how molecular motor systems have been used to accomplish work are discussed. We will conclude with prospects for future developments in this exciting field of nanotechnology.

  16. 15. Interior, Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. Interior, Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific Railroad Carlin Shops, view to northeast (90mm lens). The arched cutouts in the bottom chords of the roof trusses were necessary to provide clearance for the smokestacks of steam locomotives, and also mark the location of the former inspection pit in the floor (now filled in and covered by a new concrete floor). - Southern Pacific Railroad, Carlin Shops, Roundhouse Machine Shop Extension, Foot of Sixth Street, Carlin, Elko County, NV

  17. A high speed machining algorithm for CNC machine tools

    Microsoft Academic Search

    Guk-Chan Han; Dong-II Kim; Hyo-Gyu Kim; Kibeohn Nam; Byeong-Kap Choi; Sung-Kwun Kim

    1999-01-01

    This paper introduces a high speed machining algorithm based on a look-ahead interpolation technique for the machining of 3D surface obtained by a CAD\\/CAM system. Generally, specification of CNC system for high speed machining requires an additional hardware and it burdens end users with additional cost. The purpose of this research is to develop the low cost CNC controller having

  18. Extremal asymmetric universal cloning machines

    E-print Network

    Mingming Jiang; Sixia Yu

    2012-02-08

    The trade-offs among various output fidelities of asymmetric universal cloning machines are investigated. First we find out all the attainable optimal output fidelities for the 1 to 3 asymmetric universal cloning machine and it turns out that there are two kinds of extremal asymmetric cloning machines which have to cooperate in order to achieve some of the optimal output fidelities. Second we construct a family of extremal cloning machines that includes the universal symmetric cloning machine as well as an asymmetric 1 to $1+N$ cloning machine for qudits with two different output fidelities such that the optimal trade-off between the measurement disturbance and state estimation is attained in the limit of infinite $N$.

  19. Extremal asymmetric universal cloning machines

    E-print Network

    Jiang, Mingming

    2012-01-01

    The trade-offs among various output fidelities of asymmetric universal cloning machines are investigated. First we find out all the attainable optimal output fidelities for the 1 to 3 asymmetric universal cloning machine and it turns out that there are two kinds of extremal asymmetric cloning machines which have to cooperate in order to achieve some of the optimal output fidelities. Second we construct a family of extremal cloning machines that includes the universal symmetric cloning machine as well as an asymmetric 1 to $1+N$ cloning machine for qudits with two different output fidelities such that the optimal trade-off between the measurement disturbance and state estimation is attained in the limit of infinite $N$.

  20. Quantum adiabatic machine learning

    E-print Network

    Kristen L. Pudenz; Daniel A. Lidar

    2011-09-01

    We develop an approach to machine learning and anomaly detection via quantum adiabatic evolution. In the training phase we identify an optimal set of weak classifiers, to form a single strong classifier. In the testing phase we adiabatically evolve one or more strong classifiers on a superposition of inputs in order to find certain anomalous elements in the classification space. Both the training and testing phases are executed via quantum adiabatic evolution. We apply and illustrate this approach in detail to the problem of software verification and validation.

  1. Diamond Measuring Machine

    SciTech Connect

    Krstulic, J.F.

    2000-01-27

    The fundamental goal of this project was to develop additional capabilities to the diamond measuring prototype, work out technical difficulties associated with the original device, and perform automated measurements which are accurate and repeatable. For this project, FM and T was responsible for the overall system design, edge extraction, and defect extraction and identification. AccuGem provided a lab and computer equipment in Lawrence, 3D modeling, industry expertise, and sets of diamonds for testing. The system executive software which controls stone positioning, lighting, focusing, report generation, and data acquisition was written in Microsoft Visual Basic 6, while data analysis and modeling were compiled in C/C++ DLLs. All scanning parameters and extracted data are stored in a central database and available for automated analysis and reporting. The Phase 1 study showed that data can be extracted and measured from diamond scans, but most of the information had to be manually extracted. In this Phase 2 project, all data required for geometric modeling and defect identification were automatically extracted and passed to a 3D modeling module for analysis. Algorithms were developed which automatically adjusted both light levels and stone focus positioning for each diamond-under-test. After a diamond is analyzed and measurements are completed, a report is printed for the customer which shows carat weight, summarizes stone geometry information, lists defects and their size, displays a picture of the diamond, and shows a plot of defects on a top view drawing of the stone. Initial emphasis of defect extraction was on identification of feathers, pinpoints, and crystals. Defects were plotted color-coded by industry standards for inclusions (red), blemishes (green), and unknown defects (blue). Diamonds with a wide variety of cut quality, size, and number of defects were tested in the machine. Edge extraction, defect extraction, and modeling code were tested for multiple runs of each stone. Although there were problems with a few stones, the machine automatically completed measurements on a majority of the stones tested. A demo was performed in Lawrence for AccuGem stockholders and potential investors. The demo successfully demonstrated our technology on a random stone brought by an attendee. In conclusion, the project was successful in development of the basic technology required for a diamond measuring machine. Continued improvements in lighting control, edge and defect extraction, and an increased image depth-of-field will increase the reliability and consistency of measurements. Although additional work is needed to make the machine a commercial product, there are no foreseeable technical roadblocks in that process.

  2. Photogrammetric machine vision

    NASA Astrophysics Data System (ADS)

    Haggrén, Henrik

    Photogrammetry is the art, science and technology of obtaining reliable three-dimensional information about physical objects and the environment through processes of recording, measuring, and interpreting photographic images and patterns of electromagnetic radiant energy and other phenomena. In real-time photogrammetry, and specifically when applied to machine vision, the solid state video cameras act as dynamic two-dimensional records of scences containing all the actual information for continuous gathering of three-dimensional object space data. Both passive and active real-time photogrammetric systems are discussed.

  3. Quantum time machine

    E-print Network

    Pedro F. Gonzalez-Diaz

    1997-12-06

    The continuation of Misner space into the Euclidean region is seen to imply the topological restriction that the period of the closed spatial direction becomes time-dependent. This restriction results in a modified Lorentzian Misner space in which the renormalized stress-energy tensor for quantized complex massless scalar fields becomes regular everywhere, even on the chronology horizon. A quantum-mechanically stable time machine with just the sub-microscopic size may then be constructed out of the modified Misner space, for which the semiclassical Hawking's chronology protection conjecture is no longer an obstruction.

  4. The Intimate Machine

    NSDL National Science Digital Library

    2002-01-01

    This episode of the PBS television show Scientific American Frontiers, entitled "The Intimate Machine," aired on October 22, 2002. The show is divided into four segments. Interactive, animated computer characters created at the MIT Media Lab are the focus of the first part. The second shows a virtual dog that, just like a real pet, can be trained. Advanced monitoring devices that recognize human emotions are examined in the third segment, while the final part demonstrates a furry robot that emulates human emotions. In addition to being able to view the hour-long episode in streaming video on this site, users can also browse certain Web features.

  5. Signal machines : localization of isolated accumulation Signal machines : localization of isolated

    E-print Network

    Durand-Lose, Jérôme

    Signal machines : localization of isolated accumulation Signal machines : localization of isolated'Orléans, Orléans, FRANCE 6 mars 2011 Journées Calculabilités Paris 1 / 39 #12;Signal machines : localization of isolated accumulation 1 Signal machines and isolated accumulations 2 Necessary conditions

  6. Machine Learning, Machine Vision, and the Brain Tomaso Poggio and Christian R. Shelton

    E-print Network

    Shelton, Christian R.

    Machine Learning, Machine Vision, and the Brain Tomaso Poggio and Christian R. Shelton Center) which contribute to and complement each other. Keywords: Machine Learning, Regularization, Support Vector Machine, IT Cortex, Function Approximation, Object Detection #12; Learning Theory and Algorithms

  7. Machine Learning, Machine Vision, and the Brain Tomaso Poggio and Christian R. Shelton

    E-print Network

    Shelton, Christian R.

    Machine Learning, Machine Vision, and the Brain Tomaso Poggio and Christian R. Shelton Center) which contribute to and complement each other. Keywords: Machine Learning, Regularization, Support Vector Machine, IT Cortex, Function Approximation, Object Detection #12;Learning Theory and Algorithms

  8. Stacked Extreme Learning Machines.

    PubMed

    Zhou, Hongming; Huang, Guang-Bin; Lin, Zhiping; Wang, Han; Soh, Yeng Chai

    2014-10-28

    Extreme learning machine (ELM) has recently attracted many researchers' interest due to its very fast learning speed, good generalization ability, and ease of implementation. It provides a unified solution that can be used directly to solve regression, binary, and multiclass classification problems. In this paper, we propose a stacked ELMs (S-ELMs) that is specially designed for solving large and complex data problems. The S-ELMs divides a single large ELM network into multiple stacked small ELMs which are serially connected. The S-ELMs can approximate a very large ELM network with small memory requirement. To further improve the testing accuracy on big data problems, the ELM autoencoder can be implemented during each iteration of the S-ELMs algorithm. The simulation results show that the S-ELMs even with random hidden nodes can achieve similar testing accuracy to support vector machine (SVM) while having low memory requirements. With the help of ELM autoencoder, the S-ELMs can achieve much better testing accuracy than SVM and slightly better accuracy than deep belief network (DBN) with much faster training speed. PMID:25361517

  9. Interaction with Machine Improvisation

    NASA Astrophysics Data System (ADS)

    Assayag, Gerard; Bloch, George; Cont, Arshia; Dubnov, Shlomo

    We describe two multi-agent architectures for an improvisation oriented musician-machine interaction systems that learn in real time from human performers. The improvisation kernel is based on sequence modeling and statistical learning. We present two frameworks of interaction with this kernel. In the first, the stylistic interaction is guided by a human operator in front of an interactive computer environment. In the second framework, the stylistic interaction is delegated to machine intelligence and therefore, knowledge propagation and decision are taken care of by the computer alone. The first framework involves a hybrid architecture using two popular composition/performance environments, Max and OpenMusic, that are put to work and communicate together, each one handling the process at a different time/memory scale. The second framework shares the same representational schemes with the first but uses an Active Learning architecture based on collaborative, competitive and memory-based learning to handle stylistic interactions. Both systems are capable of processing real-time audio/video as well as MIDI. After discussing the general cognitive background of improvisation practices, the statistical modelling tools and the concurrent agent architecture are presented. Then, an Active Learning scheme is described and considered in terms of using different improvisation regimes for improvisation planning. Finally, we provide more details about the different system implementations and describe several performances with the system.

  10. 3D simulation of tool machining

    Microsoft Academic Search

    Anna Puig; Llu??s Perez-Vidal; Dani Tost

    2003-01-01

    This paper describes a 3D tool machining simulation system. The initial tool and the grinding wheels are integrated with the machine tool. The application reads and interprets the CNC program code that controls the machine, it computes the positions and the motion of components and it translates the sequence of machining operations into Boolean operations. The machining is computed for

  11. Automated machinability checking for CAD\\/CAM

    Microsoft Academic Search

    Chuan-Jun Su; Amitabha Mukerjee

    1991-01-01

    The authors present a method to determine whether or not a part is machinable on a three-axis milling machine by consideration of tool motion. The method focuses on determining sets of candidate machining directions, called the basis set, and testing if the process plan generated from any particular set of machining directions succeeds in machining all of the part features.

  12. Computational Complexity of Probabilistic Turing Machines

    Microsoft Academic Search

    John T. Gill III

    1974-01-01

    Probabilistic Turing machines are Turing machines with the ability to flip coins in order to make random decisions. We allow probabilistic Turing machines small but nonzero error probability in computing number-theoretic functions. An example is given of a function computable more quickly by probabilistic Turing machines than by deterministic Turing machines. It is shown how probabilistic linear-bounded automata can simulate

  13. Lowering the barrier to applying machine learning

    Microsoft Academic Search

    Kayur Patel

    2010-01-01

    Machine learning algorithms are key components in many cutting edge applications of computation. However, the full potential of machine learning has not been realized because using machine learning is hard, even for otherwise tech-savvy developers. This is because developing with machine learning is different than normal programming. My thesis is that developers applying machine learning need new general-purpose tools that

  14. Time (hole?) machines John Byron Manchak

    E-print Network

    Manchak, John

    Time (hole?) machines John Byron Manchak Department of Philosophy, University of Washington, Box machines Hole machines Time travel General relativity a b s t r a c t Within the context of general relativity, we consider a type of "time machine" and introduce the related "hole machine". We review what

  15. Can Machines BeCan Machines Be Polite?Polite?

    E-print Network

    Covington, Michael A.

    's why some peopleThat's why some people hate computers.hate computers. #12;PreliminariesPreliminaries Seeing the computer asSeeing the computer as consciousconscious (verbal) is what triggers the hate.(verbal) is what triggers the hate. The more humanlike a machine is,The more humanlike a machine is, the ruder

  16. Standardized Curriculum for Machine Tool Operation/Machine Shop.

    ERIC Educational Resources Information Center

    Mississippi State Dept. of Education, Jackson. Office of Vocational, Technical and Adult Education.

    Standardized vocational education course titles and core contents for two courses in Mississippi are provided: machine tool operation/machine shop I and II. The first course contains the following units: (1) orientation; (2) shop safety; (3) shop math; (4) measuring tools and instruments; (5) hand and bench tools; (6) blueprint reading; (7)…

  17. Parallel machine scheduling with release time and machine eligibility restrictions

    Microsoft Academic Search

    Grisselle Centeno; Robert L. Armacost

    1997-01-01

    We present an algorithm for the problem of minimizing maximum lateness in a parallel machine environment with release dates and machine eligibility restrictions (Pm | rj, Mj | Lmax) for the special case where due dates are equal to release dates plus a constant. No preemption of jobs is allowed. The algorithm has been evaluated using real data from an

  18. Machine performance assessment and enhancement for a hexapod machine

    SciTech Connect

    Mou, J.I. [Arizona State Univ., Tempe, AZ (United States); King, C. [Sandia National Labs., Livermore, CA (United States). Integrated Manufacturing Systems Center

    1998-03-19

    The focus of this study is to develop a sensor fused process modeling and control methodology to model, assess, and then enhance the performance of a hexapod machine for precision product realization. Deterministic modeling technique was used to derive models for machine performance assessment and enhancement. Sensor fusion methodology was adopted to identify the parameters of the derived models. Empirical models and computational algorithms were also derived and implemented to model, assess, and then enhance the machine performance. The developed sensor fusion algorithms can be implemented on a PC-based open architecture controller to receive information from various sensors, assess the status of the process, determine the proper action, and deliver the command to actuators for task execution. This will enhance a hexapod machine`s capability to produce workpieces within the imposed dimensional tolerances.

  19. The Bioengineering Program Bioengineers (also called biomedical or biomechanical

    E-print Network

    Lu, Yi

    systems, dialysis and heart-lung machines, and surgery- assisting robotic devices. The Bioengineering- or Micro-economics ................. 3 Two courses in the humanities area, from specific choices 6 Two

  20. A machining potential field approach to tool path generation for multi-axis sculptured surface machining

    Microsoft Academic Search

    Chuang-jang Chiou; Yuan-shin Lee

    2002-01-01

    This paper presents a machining potential field (MPF) method to generate tool paths for multi-axis sculptured surface machining. A machining potential field is constructed by considering both the part geometry and the cutter geometry to represent the machining-oriented information on the part surface for machining planning. The largest feasible machining strip width and the optimal cutting direction at a surface

  1. Preemptive Scheduling on Selfish Machines

    Microsoft Academic Search

    Leah Epstein; Rob Van Stee

    2007-01-01

    We consider the problem of scheduling on parallel uniformly related machines, where preemptions are allowed and the machines are controlled by selfish agents. Our goal is to minimize the makespan, whereas the goal of the agents is to maximize their profit. We show that a known algorithm is monotone and can therefore be used to create a truthful mechanism for

  2. CRYOGENIC MACHINING OF KEVLAR COMPOSITES

    Microsoft Academic Search

    D. Bhattacharyya; M. N. Allen; S. J. Mander

    1993-01-01

    Previous attempts to machine Kevlar aramid fibre reinforced plastics (KFRP) with conventional cutting tools have proven to be extremely difficult. This has somewhat restricted the material's usage, often negating the advantages of its high strength to weight ratio and fatigue tolerance. The present paper describes a novel technique of machining KFRP under cryogenic conditions with remarkable results compared to those

  3. Machine Accounting. An Instructor's Guide.

    ERIC Educational Resources Information Center

    Gould, E. Noah, Ed.

    Designed to prepare students to operate the types of accounting machines used in many medium-sized businesses, this instructor's guide presents a full-year high school course in machine accounting covering 120 hours of instruction. An introduction for the instructor suggests how to adapt the guide to present a 60-hour module which would be…

  4. Machine Intelligence Alex S. Taylor

    E-print Network

    Hunt, Galen

    Machine Intelligence Alex S. Taylor Microsoft Research 7 J. J. Thomson Avenue, Cambridge, CB3 0FB with computing machines as though they exhibited intelligence, at least an intelligence of sorts. Using exam ready to treat as intelligent. Broadly, it is suggested that ordinary, everyday ideas of intelligence

  5. Knowledge-based machine translation

    Microsoft Academic Search

    Sergei Nirenburg

    1989-01-01

    This paper provides an overview of the KBMT-89 project at Carmegie Mellon University's Center for Machine Translation, as well therefore of the special number of this journal, which reports on the project. The knowledge-based approach to machine translation is presented and defended in a historical context. Various components of the system, key parts of which are described in subsequent papers

  6. Distilling Abstract Machines Beniamino Accattoli

    E-print Network

    Mazza, Damiano

    Distilling Abstract Machines Beniamino Accattoli Carnegie Mellon University & Universit`a di rather distills them: some transitions are simulated while others vanish, as they map to a notion of structural congruence. The distillation process unveils that abstract machines in fact implement weak linear

  7. Machine Shop: Scope and Sequence.

    ERIC Educational Resources Information Center

    Nashville - Davidson County Metropolitan Public Schools, TN.

    Intended for use by all machine shop instructors in the Metropolitan Nashville Public Schools, this guide provides a sequential listing of course content and scope. A course description provides a brief overview of the content of the courses offered in the machine shop program. General course objectives are then listed. Outlines of the course…

  8. Machine Trades Lab Management Guide.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Instructional Materials Lab.

    This manual was developed to guide machine trades instructors and vocational supervisors in sequencing laboratory instruction and controlling the flow of work for a 2-year machine trades training program. The first part of the guide provides information on program management (program description, safety concerns, academic issues, implementation…

  9. Parallelism in random access machines

    Microsoft Academic Search

    Steven Fortune; James Wyllie

    1978-01-01

    A model of computation based on random access machines operating in parallel and sharing a common memory is presented. The computational power of this model is related to that of traditional models. In particular, deterministic parallel RAM's can accept in polynomial time exactly the sets accepted by polynomial tape bounded Turing machines; nondeterministic RAM's can accept in polynomial time exactly

  10. Discrete Simulation of NC Machining

    Microsoft Academic Search

    Robert B. Jerard; Barry Schaudt; Ken Hauck

    1989-01-01

    We describe a method for simulating and verifying the correctness of Numerical Control (NC) programs. NC programs contain the sequence of cutting tool movements which machine raw stock into a finished object. Our method is based on a discrete approximation of the object by a set of points. A vector is passed through each of the points and machining is

  11. Sparsity in Machine Learning Sparsifiers

    E-print Network

    Magdon-Ismail, Malik

    Sparsity in Machine Learning Sparsifiers SVD Linear Regression K-means M. Magdon-Ismail Rensselaer-of-Sample Prediction f = -1 f = +1 f = ? · A pattern exists (f) · We don't know it · We have data to learn it (D) c Magdon-Ismail. Sparsity in Machine Learning: Slide 2 /23 #12;Data ndatapoints -- xt 1 -- -- xt 2

  12. Machine Learning for Intelligent Systems

    Microsoft Academic Search

    Pat Langley

    1997-01-01

    Recent research in machine learning has focused on su- pervised induction for simple classification and rein- forcement learning for simple reactive behaviors. In the process, the field has become disconnected from AI's original goal of creating complete intelligent agents. In this paper, I review recent work on machine learning for planning, language, vision, and other topics that runs counter to

  13. The machinability of inconel 718

    Microsoft Academic Search

    M. Rahman; W. K. H. Seah; T. T. Teo

    1997-01-01

    Inconel 718, a high strength, thermal resistant Nickel-based alloy, is mainly used in the aircraft industries. Due to the extreme toughness and work hardening characteristics of the alloy, the problem of machining Inconel 718 is one of ever-increasing magnitude, This paper discusses the effect of cutting conditions on the machinability of Inconel 718. Flank wear of the inserts, workpiece surface

  14. The Machine Scoring of Writing

    ERIC Educational Resources Information Center

    McCurry, Doug

    2010-01-01

    This article provides an introduction to the kind of computer software that is used to score student writing in some high stakes testing programs, and that is being promoted as a teaching and learning tool to schools. It sketches the state of play with machines for the scoring of writing, and describes how these machines work and what they do.…

  15. Anaesthesia machine: checklist, hazards, scavenging.

    PubMed

    Goneppanavar, Umesh; Prabhu, Manjunath

    2013-09-01

    From a simple pneumatic device of the early 20(th) century, the anaesthesia machine has evolved to incorporate various mechanical, electrical and electronic components to be more appropriately called anaesthesia workstation. Modern machines have overcome many drawbacks associated with the older machines. However, addition of several mechanical, electronic and electric components has contributed to recurrence of some of the older problems such as leak or obstruction attributable to newer gadgets and development of newer problems. No single checklist can satisfactorily test the integrity and safety of all existing anaesthesia machines due to their complex nature as well as variations in design among manufacturers. Human factors have contributed to greater complications than machine faults. Therefore, better understanding of the basics of anaesthesia machine and checking each component of the machine for proper functioning prior to use is essential to minimise these hazards. Clear documentation of regular and appropriate servicing of the anaesthesia machine, its components and their satisfactory functioning following servicing and repair is also equally important. Trace anaesthetic gases polluting the theatre atmosphere can have several adverse effects on the health of theatre personnel. Therefore, safe disposal of these gases away from the workplace with efficiently functioning scavenging system is necessary. Other ways of minimising atmospheric pollution such as gas delivery equipment with negligible leaks, low flow anaesthesia, minimal leak around the airway equipment (facemask, tracheal tube, laryngeal mask airway, etc.) more than 15 air changes/hour and total intravenous anaesthesia should also be considered. PMID:24249887

  16. 7 CFR 58.429 - Washing machine.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...2011-01-01 2011-01-01 false Washing machine. 58.429 Section 58.429 Agriculture...Equipment and Utensils § 58.429 Washing machine. When used, the washing machine for cheese cloths and bandages shall be...

  17. 7 CFR 58.429 - Washing machine.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...2010-01-01 2010-01-01 false Washing machine. 58.429 Section 58.429 Agriculture...Equipment and Utensils § 58.429 Washing machine. When used, the washing machine for cheese cloths and bandages shall be...

  18. 49 CFR 173.174 - Refrigerating machines.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...2010-10-01 2010-10-01 false Refrigerating machines. 173.174 Section 173.174 Transportation...Class 1 and Class 7 § 173.174 Refrigerating machines. A refrigerating machine assembled for shipment and containing 7 kg...

  19. 48 CFR 908.7103 - Office machines.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...2010-10-01 2010-10-01 false Office machines. 908.7103 Section 908.7103 Federal...Acquisition of Special Items 908.7103 Office machines. Acquisitions of office machines by DOE offices and its authorized...

  20. 48 CFR 908.7103 - Office machines.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...2011-10-01 2011-10-01 false Office machines. 908.7103 Section 908.7103 Federal...Acquisition of Special Items 908.7103 Office machines. Acquisitions of office machines by DOE offices and its authorized...

  1. 49 CFR 173.174 - Refrigerating machines.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...2011-10-01 2011-10-01 false Refrigerating machines. 173.174 Section 173.174 Transportation...Class 1 and Class 7 § 173.174 Refrigerating machines. A refrigerating machine assembled for shipment and containing 7 kg...

  2. Extremal quantum cloning machines

    SciTech Connect

    Chiribella, G.; D'Ariano, G. M.; Perinotti, P.; Cerf, N.J. [QUIT Quantum Information Theory Group of the INFM, Unita di Pavia and Dipartimento di Fisica 'A. Volta', via Bassi 6, I-27100 Pavia (Italy); QUIC, Ecole Polytechnique, Universite Libre de Bruxelles, 1050 Brussels (Belgium)

    2005-10-15

    We investigate the problem of cloning a set of states that is invariant under the action of an irreducible group representation. We then characterize the cloners that are extremal in the convex set of group covariant cloning machines, among which one can restrict the search for optimal cloners. For a set of states that is invariant under the discrete Weyl-Heisenberg group, we show that all extremal cloners can be unitarily realized using the so-called double-Bell states, whence providing a general proof of the popular ansatz used in the literature for finding optimal cloners in a variety of settings. Our result can also be generalized to continuous-variable optimal cloning in infinite dimensions, where the covariance group is the customary Weyl-Heisenberg group of displacement000.

  3. An Experimental LISP Machine

    NASA Astrophysics Data System (ADS)

    Lun, Wang

    1987-04-01

    This paper presents a multi-microprocessor LISP machine whose goal is to exploit the inherent parallelism in the LISP programs fully. The base architecture is a MIMD architecture based on a hybrid model for combinating data driven, demand driven and VoN Neumann process schemes. The basic evaluation strategy is data driven. Lazy evaluation mechanism is introduced to avoid unnecessary and unsafe computations. An experimental system with the four processor elements has been built in HIT, China. The system consists of a Z80 microcomputer and three TP8O1s interconnected through three buses. Each processor evaluates a part of programs asynchronously. The shared memory is divided into two parts: list cell area and enviroment area, each of which has the indepen-dent common bus to avoid the bus bottleneck.

  4. Applications of the connection machine

    SciTech Connect

    Waltz, D.L.

    1987-01-01

    The Connection Machine development effort was initiated in the belief that parallel processing and artificial intelligence could together accelerate the rate of progress toward truly intelligent machines. This progress is the result of the ease with which the machine can be programmed and the dramatic increase in compute power that the machine can bring to bear. The authors have been able to run many trials of experiments in instances where previously, running just one would have been considered an achievement and no further experimentation would have been done. This has enabled exploring a great many more hypotheses and to work on much larger problems that had been possible on previous-generation artificial intelligence workstations. The ease of programming is in part the result of a decision to use existing serial machines (the Symbolics 3600 or Digital Equipment Corporation VAX), thus leaving unchanged the operating systems, editors, file systems, debuggers, network communications systems, and so on, so as to provide familiar programming environments. The Connection Machine is programmed in conservative extensions of Common Lisp and C. Users familiar with these languages and with front-end computer systems have been able to produce results on the Connection Machine on the first day that they use it.

  5. A Boltzmann machine for the organization of intelligent machines

    NASA Technical Reports Server (NTRS)

    Moed, Michael C.; Saridis, George N.

    1990-01-01

    A three-tier structure consisting of organization, coordination, and execution levels forms the architecture of an intelligent machine using the principle of increasing precision with decreasing intelligence from a hierarchically intelligent control. This system has been formulated as a probabilistic model, where uncertainty and imprecision can be expressed in terms of entropies. The optimal strategy for decision planning and task execution can be found by minimizing the total entropy in the system. The focus is on the design of the organization level as a Boltzmann machine. Since this level is responsible for planning the actions of the machine, the Boltzmann machine is reformulated to use entropy as the cost function to be minimized. Simulated annealing, expanding subinterval random search, and the genetic algorithm are presented as search techniques to efficiently find the desired action sequence and illustrated with numerical examples.

  6. Universal Developer Platform for MachinePlatform for Machine

    E-print Network

    be found in any software (office, development, control etc.) Handling of sensors, construction plans, busVerse of the ViVids Control and Guidance applications Automation of any kind of machines Robotics June 24-26, 2008

  7. Intelligible machine learning with malibu.

    PubMed

    Langlois, Robert E; Lu, Hui

    2008-01-01

    malibu is an open-source machine learning work-bench developed in C/C++ for high-performance real-world applications, namely bioinformatics and medical informatics. It leverages third-party machine learning implementations for more robust bug-free software. This workbench handles several well-studied supervised machine learning problems including classification, regression, importance-weighted classification and multiple-instance learning. The malibu interface was designed to create reproducible experiments ideally run in a remote and/or command line environment. The software can be found at: http://proteomics.bioengr. uic.edu/malibu/index.html. PMID:19163538

  8. Slide system for machine tools

    DOEpatents

    Douglass, Spivey S. (Oak Ridge, TN); Green, Walter L. (Knoxville, TN)

    1982-01-01

    The present invention relates to a machine tool which permits the machining of nonaxisymmetric surfaces on a workpiece while rotating the workpiece about a central axis of rotation. The machine tool comprises a conventional two-slide system (X-Y) with one of these slides being provided with a relatively short travel high-speed auxiliary slide which carries the material-removing tool. The auxiliary slide is synchronized with the spindle speed and the position of the other two slides and provides a high-speed reciprocating motion required for the displacement of the cutting tool for generating a nonaxisymmetric surface at a selected location on the workpiece.

  9. Slide system for machine tools

    DOEpatents

    Douglass, S.S.; Green, W.L.

    1980-06-12

    The present invention relates to a machine tool which permits the machining of nonaxisymmetric surfaces on a workpiece while rotating the workpiece about a central axis of rotation. The machine tool comprises a conventional two-slide system (X-Y) with one of these slides being provided with a relatively short travel high-speed auxiliary slide which carries the material-removing tool. The auxiliary slide is synchronized with the spindle speed and the position of the other two slides and provides a high-speed reciprocating motion required for the displacement of the cutting tool for generating a nonaxisymmetric surface at a selected location on the workpiece.

  10. HUMAN MACHINE COOPERATIVE TELEROBOTICS

    SciTech Connect

    William R. Hamel; Spivey Douglass; Sewoong Kim; Pamela Murray; Yang Shou; Sriram Sridharan; Ge Zhang; Scott Thayer; Rajiv V. Dubey

    2003-06-30

    The remediation and deactivation and decommissioning (D&D) of nuclear waste storage tanks using telerobotics is one of the most challenging tasks faced in environmental cleanup. Since a number of tanks have reached the end of their design life and some of them have leaks, the unstructured, uncertain and radioactive environment makes the work inefficient and expensive. However, the execution time of teleoperation consumes ten to hundred times that of direct contact with an associated loss in quality. Thus, a considerable effort has been expended to improve the quality and efficiency of telerobotics by incorporating into teleoperation and robotic control functions such as planning, trajectory generation, vision, and 3-D modeling. One example is the Robot Task Space Analyzer (RTSA), which has been developed at the Robotics and Electromechanical Systems Laboratory (REMSL) at the University of Tennessee in support of the D&D robotic work at the Oak Ridge National Laboratory and the National Energy Technology Laboratory. This system builds 3-D models of the area of interest in task space through automatic image processing and/or human interactive manual modeling. The RTSA generates a task plan file, which describes the execution of a task including manipulator and tooling motions. The high level controller of the manipulator interprets the task plan file and executes the task automatically. Thus, if the environment is not highly unstructured, a tooling task, which interacts with environment, will be executed in the autonomous mode. Therefore, the RTSA not only increases the system efficiency, but also improves the system reliability because the operator will act as backstop for safe operation after the 3-D models and task plan files are generated. However, unstructured conditions of environment and tasks necessitate that the telerobot operates in the teleoperation mode for successful execution of task. The inefficiency in the teleoperation mode led to the research described as Human Machine Cooperative Telerobotics (HMCTR). The HMCTR combines the telerobot with robotic control techniques to improve the system efficiency and reliability in teleoperation mode. In this topical report, the control strategy, configuration and experimental results of Human Machines Cooperative Telerobotics (HMCTR), which modifies and limits the commands of human operator to follow the predefined constraints in the teleoperation mode, is described. The current implementation is a laboratory-scale system that will be incorporated into an engineering-scale system at the Oak Ridge National Laboratory in the future.

  11. Ubiquitous-based mobile control and monitoring of CNC machines for development of u-machine

    Microsoft Academic Search

    Dong-Hoon Kim; Jun-Yeob Song

    2006-01-01

    This study was an attempt to control and monitor Computerized Numerical Controller (CNC) machines anywhere and anytime for\\u000a the development of a ubiquitous machine (u-machine). With a Personal Digital Assistant (PDA) phone, the machine status and\\u000a machining data of CNC machines can be monitored in wired and wireless environments, including the environments of IMT2000\\u000a and Wireless LAN. Moreover, CNC machines

  12. Virtual machine performance benchmarking.

    PubMed

    Langer, Steve G; French, Todd

    2011-10-01

    The attractions of virtual computing are many: reduced costs, reduced resources and simplified maintenance. Any one of these would be compelling for a medical imaging professional attempting to support a complex practice on limited resources in an era of ever tightened reimbursement. In particular, the ability to run multiple operating systems optimized for different tasks (computational image processing on Linux versus office tasks on Microsoft operating systems) on a single physical machine is compelling. However, there are also potential drawbacks. High performance requirements need to be carefully considered if they are to be executed in an environment where the running software has to execute through multiple layers of device drivers before reaching the real disk or network interface. Our lab has attempted to gain insight into the impact of virtualization on performance by benchmarking the following metrics on both physical and virtual platforms: local memory and disk bandwidth, network bandwidth, and integer and floating point performance. The virtual performance metrics are compared to baseline performance on "bare metal." The results are complex, and indeed somewhat surprising. PMID:21207096

  13. Semismooth support vector machines.

    SciTech Connect

    Ferris, M. C.; Munson, T. S.; Mathematics and Computer Science; Univ. of Wisconsin

    2004-09-01

    The linear support vector machine can be posed as a quadratic program in a variety of ways. In this paper, we look at a formulation using the two-norm for the misclassification error that leads to a positive definite quadratic program with a single equality constraint when the Wolfe dual is taken. The quadratic term is a small rank update to a positive definite matrix. We reformulate the optimality conditions as a semismooth system of equations using the Fischer-Burmeister function and apply a damped Newton method to solve the resulting problem. The algorithm is shown to converge from any starting point with a Q-quadratic rate of convergence. At each iteration, we use the Sherman-Morrison-Woodbury update formula to solve a single linear system of equations. Significant computational savings are realized as the inactive variables are identified and exploited during the solution process. Results for a 60 million variable problem are presented, demonstrating the effectiveness of the proposed method on a personal computer.

  14. Creating living machines

    PubMed Central

    Kamm, Roger D.; Bashir, Rashid

    2015-01-01

    Development of increasingly complex integrated cellular systems will be a major challenge for the next decade and beyond, as we apply the knowledge gained from the sub-disciplines of tissue engineering, synthetic biology, micro-fabrication and nanotechnology, systems biology, and developmental biology. In this prospective, we describe the current state-of-the-art in the context of differentiating source cells from more primitive, pluripotent cells, and organizing these cells into populations of a single cell type to produce the components or building blocks of higher order systems and finally, combining multiple cell types, possibly in combination with scaffolds possessing specific physical or chemical properties, to produce greater functionality. As these “living machines” increase in capabilities, exhibit emergent behavior and potentially reveal the ability for self-assembly, self-repair, and even self-replication, questions arise regarding the ethical implications of this work. Future prospects as well as ways of addressing these complex ethical questions will be addressed. PMID:24006130

  15. Video time encoding machines.

    PubMed

    Lazar, Aurel A; Pnevmatikakis, Eftychios A

    2011-03-01

    We investigate architectures for time encoding and time decoding of visual stimuli such as natural and synthetic video streams (movies, animation). The architecture for time encoding is akin to models of the early visual system. It consists of a bank of filters in cascade with single-input multi-output neural circuits. Neuron firing is based on either a threshold-and-fire or an integrate-and-fire spiking mechanism with feedback. We show that analog information is represented by the neural circuits as projections on a set of band-limited functions determined by the spike sequence. Under Nyquist-type and frame conditions, the encoded signal can be recovered from these projections with arbitrary precision. For the video time encoding machine architecture, we demonstrate that band-limited video streams of finite energy can be faithfully recovered from the spike trains and provide a stable algorithm for perfect recovery. The key condition for recovery calls for the number of neurons in the population to be above a threshold value. PMID:21296708

  16. Language Resources and Machine Learning

    E-print Network

    Erjavec, Toma?

    Language Resources and Machine Learning Saso Dzeroski Department of Knowledge Technologies Institut technologies and linguistics · Language resources · The Multext-East resources ­ Learning morphological analysis/synthesis ­ Learning PoS tagging ­ Lemmatization · The Prague Dependency Treebank ­ Learning

  17. Machine Learning for Global Optimization

    E-print Network

    schoen,,,

    approach for global optimization in which machine learning is used to predict ..... graphs of Schwefel function for n = 1 or n = 2 reveals that this problem has a ...... can we prune the solution space when considering deep space manoeuvres?

  18. Position monitor for mining machines

    NASA Technical Reports Server (NTRS)

    Lubich, J.

    1980-01-01

    Circuit at output of incremental transducer records progress of longwall shearer. In contrast to mechanical shaft encoders, electronic circuit can be easily packaged to withstand shock and vibration of mining machine as it cuts across coal seam.

  19. Z Machine at Sandia Labs

    SciTech Connect

    2007-10-17

    Sandia Labs' Z machine is the largest laboratory source of x-rays in the world. For the few nanoseconds of a Z Machine test, its electrical output equals the output of 50x the electrical generating stations of all the power plants on earth. The Z Machine complex encompasses an area roughly the size of a major college basketball arena. Originally created to validate nuclear weapons models, the Z Machine is also considered a "dark horse" in the race for viable fusion energy production. After the famous "arcs and sparks" photo of Z (a photo no longer possible after its refurbishment), this is a fast-motion video of workers completing Z's recent refurbishment.

  20. Machine Translation: Learning without Word

    E-print Network

    Smith, David A.

    Machine Translation: Learning without Word Alignments Introduction to Natural Language Processing - Models will automatically learn entries in probabilistic translation dictionaries, for instance p lookup in existing dictionary 8 #12;Learning Word Translation Dictionaries Using Minimal Resources 9 #12

  1. Diamond turning machine controller implementation

    SciTech Connect

    Garrard, K.P.; Taylor, L.W.; Knight, B.F.; Fornaro, R.J.

    1988-12-01

    The standard controller for a Pnuemo ASG 2500 Diamond Turning Machine, an Allen Bradley 8200, has been replaced with a custom high-performance design. This controller consists of four major components. Axis position feedback information is provided by a Zygo Axiom 2/20 laser interferometer with 0.1 micro-inch resolution. Hardware interface logic couples the computers digital and analog I/O channels to the diamond turning machine`s analog motor controllers, the laser interferometer, and other machine status and control information. It also provides front panel switches for operator override of the computer controller and implement the emergency stop sequence. The remaining two components, the control computer hardware and software, are discussed in detail below.

  2. Cooling Towers, Energy Conservation Machines 

    E-print Network

    Burger, R.

    1980-01-01

    ------------~'l:~' COOLING TOWERS, ENERGY CONSERVATION MACHINES 1980 CONFERENCE ON INDUSTRIAL ENERGY CONSERVATION TECHNOLOGY Robert Burger B~rger Associates Dallas, Texas ABSTRACT Cooling towers, in all too many industrial plants, are often...

  3. Machine Code Programming and Logic

    Microsoft Academic Search

    Mark Priestley

    \\u000a The task of programming an automatic calculator or computer, usually referred to as ’coding’, was understood to be that of\\u000a specifying the sequence of operations that the machine would carry out in the course of a computation. Many different order\\u000a codes were possible for stored-program machines, and it was only through practical experience that the features of a successful\\u000a code

  4. Building and simulating protein machines

    NASA Astrophysics Data System (ADS)

    Katebi, Ataur Rahim

    Glycolysis is a central metabolic pathway, present in almost all organisms, that produces energy. The pathway has been extensively investigated by biochemists. There is a significant body of structural and biochemical information about this pathway. The complete pathway is a ten step process. At each step, a specific chemical reaction is catalyzed by a specific enzyme. Fructose bisphosphate aldolase (FBA) and triosephosphate isomerase (TIM) catalyze the fourth and the fifth steps on the pathway. This thesis investigates the possible substrate transfer mechanism between FBA and TIM. FBA cleaves its substrate, the six-carbon fructose-1,6-bisphosphate (FBP), into two three-carbon products -- glyceraldehydes 3-phosphate (GAP) and dihydroxy acetone phosphate (DHAP). One component of these two products, DHAP, is the substrate for TIM and the other component GAP goes directly to GAPDH, the subsequent enzyme on the pathway. TIM converts DHAP to GAP and delivers the product to GAPDH. I employ Elastic Network Models (ENM) to investigate the mechanistic and dynamic aspects of the functionality of FBA and TIM enzymes -- (1) the effects of the oligomerization of these two enzymes on their functional dynamics and the coordination of the individual protein's structural components along the functional region; and (2) the mechanistic synchrony of these two protein machines that may enable them to operate in a coordinated fashion as a conjugate machine -- transferring the product from FBA as substrate to TIM. A macromolecular machine comprised of FBA and TIM will facilitate the substrate catalysis mechanism and the product flow between FBA and TIM. Such a machine could be used as a functional unit in building a larger a machine for the structural modeling of the whole glycolysis pathway. Building such machines for the glycolysis pathway may reveal the interplay of the enzymes as a complete machine. Also the methods and insights developed from the efforts to build such large machines could be applied to build macromolecular structures for other biologically important clusters of interacting enzymes centered around individual metabolic pathways.

  5. Safety checking of machine code

    Microsoft Academic Search

    Zhichen Xu; Barton P. Miller; Thomas Reps

    2000-01-01

    We show how to determine statically whether it is safe for untrusted machine code to be loaded into a trusted host system.Our safety-checking technique operates directly on the untrusted machine-code program, requiring only that the initial inputs to the untrusted program be annotated with typestate information and linear constraints. This approach opens up the possibility of being able to certify

  6. The Gamma Database Machine Project

    Microsoft Academic Search

    David J. Dewitt; Shahram Ghandeharizadeh; Donovan A. Schneider; Allan Bricker; Hui-i Hsiao; Rick Rasmussen

    1990-01-01

    This paper describes the design of the Gamma database machine and the techniques employed in its implementation.Gamma is a relational database machine currently operating on an Intel iPSC\\/2 hypercube with 32 processorsand 32 disk drives. Gamma employs three key technical ideas which enable the architecture to be scaled to100s of processors. First, all relations are horizontally partitioned across multiple disk

  7. Wax Reinforces Honeycomb During Machining

    NASA Technical Reports Server (NTRS)

    Towell, Timothy W.; Fahringer, David T.; Vasquez, Peter; Scheidegger, Alan P.

    1995-01-01

    Method of machining on conventional metal lathe devised for precise cutting of axisymmetric contours on honeycomb cores made of composite (matrix/fiber) materials. Wax filling reinforces honeycomb walls against bending and tearing while honeycomb being contoured on lathe. Innovative method of machining on lathe involves preparation in which honeycomb is placed in appropriate fixture and the fixture is then filled with molten water-soluble wax. Number of different commercial waxes have been tried.

  8. Adaptive machine vision. Annual report

    SciTech Connect

    Stoner, W.W.; Brill, M.H.; Bergeron, D.W.

    1988-03-08

    The mission of the Strategic Defense Initiative is to develop defenses against threatening ballistic missiles. There are four distinct phases to the SDI defense; boost, post-boost, midcourse and terminal. In each of these phases, one or more machine-vision functions are required, such as pattern recognition, stereo image fusion, clutter rejection and discrimination. The SDI missions of coarse track, stereo track and discrimination are examined here from the point of view of a machine-vision system.

  9. COMPILER FOR TINY REGISTER MACHINE 

    E-print Network

    Wu, Sidian

    2014-09-20

    . The advent in the recent years of inexpensive development boards with sizeable and fast FPGA chips has made it possible for us to design and deploy embedded system architectures with a significant number (32 or more) of cores. Some research has gone.... 4 CHAPTER II BACKGROUND Tiny Register Machine Tiny Register Machine (TRM) is a straightforward RISC architecture implemented of a Field Programmable Gate Array (FPGA) [1] by Dr. Niklaus Wirth. TRM was initially designed for educational...

  10. Development of Electrochemical Micro Machining

    E-print Network

    Srinivas Sundarram, Sriharsha

    2008-10-10

    DEVELOPMENT OF ELECTROCHEMICAL MICRO MACHINING A Thesis by SRIHARSHA SRINIVAS SUNDARRAM Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment of the requirements for the degree of MASTER... OF SCIENCE August 2008 Major Subject: Mechanical Engineering DEVELOPMENT OF ELECTROCHEMICAL MICRO MACHINING A Thesis by SRIHARSHA SRINIVAS SUNDARRAM Submitted to the Office of Graduate Studies of Texas A&M University in partial...

  11. An introduc+on to Machine Learning

    E-print Network

    Wehenkel, Louis

    An introduc+on to Machine Learning Pierre Geurts p/frameworks #12;3 Machine Learning: defini+on l Machine Learning is concerned with the developmentUer understand the system #12;4 Machine learning: when ? l Learning is useful when: l Human

  12. An introducWon to Machine Learning

    E-print Network

    Wehenkel, Louis

    An introducWon to Machine Learning Pierre Geurts p.geurts@ulg.ac.be Department of EE and CS Other learning protocols/frameworks #12;3 Machine Learning: definiWon Machine Learning is concernedWon and beXer understand the system #12;4 Machine learning: when ? Learning is useful when: Human

  13. pdf version of the entry Time Machines

    E-print Network

    Wüthrich, Christian

    pdf version of the entry Time Machines http://plato.stanford.edu/archives/win2010/entries/time-machine, Stanford, CA 94305 Time Machines Copyright c 2010 by the authors John Earman and Christian W¨uthrich All rights reserved. Copyright policy: https://leibniz.stanford.edu/friends/info/copyright/ Time Machines

  14. Model-based machine learning.

    PubMed

    Bishop, Christopher M

    2013-02-13

    Several decades of research in the field of machine learning have resulted in a multitude of different algorithms for solving a broad range of problems. To tackle a new application, a researcher typically tries to map their problem onto one of these existing methods, often influenced by their familiarity with specific algorithms and by the availability of corresponding software implementations. In this study, we describe an alternative methodology for applying machine learning, in which a bespoke solution is formulated for each new application. The solution is expressed through a compact modelling language, and the corresponding custom machine learning code is then generated automatically. This model-based approach offers several major advantages, including the opportunity to create highly tailored models for specific scenarios, as well as rapid prototyping and comparison of a range of alternative models. Furthermore, newcomers to the field of machine learning do not have to learn about the huge range of traditional methods, but instead can focus their attention on understanding a single modelling environment. In this study, we show how probabilistic graphical models, coupled with efficient inference algorithms, provide a very flexible foundation for model-based machine learning, and we outline a large-scale commercial application of this framework involving tens of millions of users. We also describe the concept of probabilistic programming as a powerful software environment for model-based machine learning, and we discuss a specific probabilistic programming language called Infer.NET, which has been widely used in practical applications. PMID:23277612

  15. Gaussian processes for machine learning.

    PubMed

    Seeger, Matthias

    2004-04-01

    Gaussian processes (GPs) are natural generalisations of multivariate Gaussian random variables to infinite (countably or continuous) index sets. GPs have been applied in a large number of fields to a diverse range of ends, and very many deep theoretical analyses of various properties are available. This paper gives an introduction to Gaussian processes on a fairly elementary level with special emphasis on characteristics relevant in machine learning. It draws explicit connections to branches such as spline smoothing models and support vector machines in which similar ideas have been investigated. Gaussian process models are routinely used to solve hard machine learning problems. They are attractive because of their flexible non-parametric nature and computational simplicity. Treated within a Bayesian framework, very powerful statistical methods can be implemented which offer valid estimates of uncertainties in our predictions and generic model selection procedures cast as nonlinear optimization problems. Their main drawback of heavy computational scaling has recently been alleviated by the introduction of generic sparse approximations.13,78,31 The mathematical literature on GPs is large and often uses deep concepts which are not required to fully understand most machine learning applications. In this tutorial paper, we aim to present characteristics of GPs relevant to machine learning and to show up precise connections to other "kernel machines" popular in the community. Our focus is on a simple presentation, but references to more detailed sources are provided. PMID:15112367

  16. Estimation of NC machining time using NC block distribution for sculptured surface machining

    Microsoft Academic Search

    Eun-Young Heo; Dong-Won Kim; Bo-Hyun Kim; F. Frank Chen

    2006-01-01

    The estimation of NC machining time is of importance because it provides manufacturing engineers with information to accurately predict the productivity of an NC machine, as well as its production schedule. NC programs contain various machining information, such as tool positions, feed and speed rates, and other machine instructions. Nominal NC machining time can easily be obtained based on the

  17. Simulations of Electrical Machines and Drives using the Machines and the SmartElectricDrives Library

    Microsoft Academic Search

    Johannes Vinzenz Gragger; Anton Haumer; Thomas Bäuml; Hansjörg Kapeller

    2009-01-01

    The tutorial starts with an introduction to electric machines. This includes DC machines, asynchronous ma- chines and permanent magnet synchronous machines. Simple applications of starting and operating the ma- chines will be presented using the Machines package of the Modelica Standard Library. The limits of opera- tion of open loop and mains supplied machines will be discussed. For operating electric

  18. Probability Machines: Consistent Probability Estimation Using Nonparametric Learning Machines

    PubMed Central

    Malley, J. D.; Kruppa, J.; Dasgupta, A.; Malley, K. G.; Ziegler, A.

    2011-01-01

    Summary Background Most machine learning approaches only provide a classification for binary responses. However, probabilities are required for risk estimation using individual patient characteristics. It has been shown recently that every statistical learning machine known to be consistent for a nonparametric regression problem is a probability machine that is provably consistent for this estimation problem. Objectives The aim of this paper is to show how random forests and nearest neighbors can be used for consistent estimation of individual probabilities. Methods Two random forest algorithms and two nearest neighbor algorithms are described in detail for estimation of individual probabilities. We discuss the consistency of random forests, nearest neighbors and other learning machines in detail. We conduct a simulation study to illustrate the validity of the methods. We exemplify the algorithms by analyzing two well-known data sets on the diagnosis of appendicitis and the diagnosis of diabetes in Pima Indians. Results Simulations demonstrate the validity of the method. With the real data application, we show the accuracy and practicality of this approach. We provide sample code from R packages in which the probability estimation is already available. This means that all calculations can be performed using existing software. Conclusions Random forest algorithms as well as nearest neighbor approaches are valid machine learning methods for estimating individual probabilities for binary responses. Freely available implementations are available in R and may be used for applications. PMID:21915433

  19. Autonomous agent for on-machine acceptance of machined components

    NASA Astrophysics Data System (ADS)

    Pancerella, Carmen M.; Hazelton, Andrew J.; Frost, H. R.

    1995-11-01

    In recent years, manufacturers of high precision mechanical parts have been required to produce increasingly complex designs, in smaller lot sizes, with improved quality. These requirements demand lower process costs, shorter development cycles and more accurate manufacturing technologies. To meet these demands, manufacturers are attempting to both improve process quality and provide better CAD/CAM integration. The technique of on- machine acceptance provides one mechanisms for improving the part inspection and verification process. This approach allows one machine and one process capability model to be used for both fabrication and inspection, reducing capital cost and overall cycle time. However, the on-machine acceptance technique possesses greater potential than as simply an alternative mechanism for verifying part geometry. If the inspection capability information generated by on-machine acceptance processes can be made available to designers, it can be used to create a design-for-inspectability environment and help realize the benefits of concurrent engineering. This paper proposes a novel architecture which integrates on-machine acceptance with an agent-based concurrent design environment, for reducing both the cost and production time for high quality, small lot size, mechanical parts. This work has focused on the production of stainless steel pressure vessels at the Integrated Manufacturing Technology Laboratory manufacturing cell, located at Sandia National Laboratories, California.

  20. Machine vision systems using machine learning for industrial product inspection

    NASA Astrophysics Data System (ADS)

    Lu, Yi; Chen, Tie Q.; Chen, Jie; Zhang, Jian; Tisler, Anthony

    2002-02-01

    Machine vision inspection requires efficient processing time and accurate results. In this paper, we present a machine vision inspection architecture, SMV (Smart Machine Vision). SMV decomposes a machine vision inspection problem into two stages, Learning Inspection Features (LIF), and On-Line Inspection (OLI). The LIF is designed to learn visual inspection features from design data and/or from inspection products. During the OLI stage, the inspection system uses the knowledge learnt by the LIF component to inspect the visual features of products. In this paper we will present two machine vision inspection systems developed under the SMV architecture for two different types of products, Printed Circuit Board (PCB) and Vacuum Florescent Displaying (VFD) boards. In the VFD board inspection system, the LIF component learns inspection features from a VFD board and its displaying patterns. In the PCB board inspection system, the LIF learns the inspection features from the CAD file of a PCB board. In both systems, the LIF component also incorporates interactive learning to make the inspection system more powerful and efficient. The VFD system has been deployed successfully in three different manufacturing companies and the PCB inspection system is the process of being deployed in a manufacturing plant.

  1. Analysis and design of asymmetrical reluctance machine

    NASA Astrophysics Data System (ADS)

    Harianto, Cahya A.

    Over the past few decades the induction machine has been chosen for many applications due to its structural simplicity and low manufacturing cost. However, modest torque density and control challenges have motivated researchers to find alternative machines. The permanent magnet synchronous machine has been viewed as one of the alternatives because it features higher torque density for a given loss than the induction machine. However, the assembly and permanent magnet material cost, along with safety under fault conditions, have been concerns for this class of machine. An alternative machine type, namely the asymmetrical reluctance machine, is proposed in this work. Since the proposed machine is of the reluctance machine type, it possesses desirable feature, such as near absence of rotor losses, low assembly cost, low no-load rotational losses, modest torque ripple, and rather benign fault conditions. Through theoretical analysis performed herein, it is shown that this machine has a higher torque density for a given loss than typical reluctance machines, although not as high as the permanent magnet machines. Thus, the asymmetrical reluctance machine is a viable and advantageous machine alternative where the use of permanent magnet machines are undesirable.

  2. Mechanical design of walking machines.

    PubMed

    Arikawa, Keisuke; Hirose, Shigeo

    2007-01-15

    The performance of existing actuators, such as electric motors, is very limited, be it power-weight ratio or energy efficiency. In this paper, we discuss the method to design a practical walking machine under this severe constraint with focus on two concepts, the gravitationally decoupled actuation (GDA) and the coupled drive. The GDA decouples the driving system against the gravitational field to suppress generation of negative power and improve energy efficiency. On the other hand, the coupled drive couples the driving system to distribute the output power equally among actuators and maximize the utilization of installed actuator power. First, we depict the GDA and coupled drive in detail. Then, we present actual machines, TITAN-III and VIII, quadruped walking machines designed on the basis of the GDA, and NINJA-I and II, quadruped wall walking machines designed on the basis of the coupled drive. Finally, we discuss walking machines that travel on three-dimensional terrain (3D terrain), which includes the ground, walls and ceiling. Then, we demonstrate with computer simulation that we can selectively leverage GDA and coupled drive by walking posture control. PMID:17148055

  3. Dry machinability of aluminum alloys.

    SciTech Connect

    Shareef, I.; Natarajan, M.; Ajayi, O. O.; Energy Technology; Department of IMET

    2005-01-01

    Adverse effects of the use of cutting fluids and environmental concerns with regard to cutting fluid disposability is compelling industry to adopt Dry or near Dry Machining, with the aim of eliminating or significantly reducing the use of metal working fluids. Pending EPA regulations on metal cutting, dry machining is becoming a hot topic of research and investigation both in industry and federal research labs. Although the need for dry machining may be apparent, most of the manufacturers still consider dry machining to be impractical and even if possible, very expensive. This perception is mainly due to lack of appropriate cutting tools that can withstand intense heat and Built-up-Edge (BUE) formation during dry machining. The challenge of heat dissipation without coolant requires a completely different approach to tooling. Special tooling utilizing high-performance multi-layer, multi-component, heat resisting, low friction coatings could be a plausible answer to the challenge of dry machining. In pursuit of this goal Argonne National Labs has introduced Nano-crystalline near frictionless carbon (NFC) diamond like coatings (DLC), while industrial efforts have led to the introduction of composite coatings such as titanium aluminum nitride (TiAlN), tungsten carbide/carbon (WC/C) and others. Although, these coatings are considered to be very promising, they have not been tested either from tribological or from dry machining applications point of view. As such a research program in partnership with federal labs and industrial sponsors has started with the goal of exploring the feasibility of dry machining using the newly developed coatings such as Near Frictionless Carbon Coatings (NFC), Titanium Aluminum Nitride (TiAlN), and multi-layer multicomponent nano coatings such as TiAlCrYN and TiAlN/YN. Although various coatings are under investigation as part of the overall dry machinability program, this extended abstract deals with a systematic investigation of dry machinability of Aluminum 6061 and 2024 using uncoated carbide, TiN coated carbide, and TiAlN coated carbide inserts. Central Composite Design (CCD) is used to study the effect of speed, feed, depth of cut, workpiece material, and cutting tool material on the resulting forces, surface finish, temperature, chip morphology and tool wear. Each of the machining responses is measured and compared under 15 different machining conditions. Results from CCD experiments have been used to develop linear and logarithmic models for forces (Fx, Fy, Fz, & Fr) surface finish (Ra), and temperature. Furthermore, chip morphology and tool wear have also been compared. From the comparison of forces, surface finish, temperature, chip morphology, tool wear and the corresponding statistical models, it is clear that in general TiAlN results in lower forces, better surface finish, greater fragmented chips, and lesser tool wear.

  4. Minimal universal quantum heat machine.

    PubMed

    Gelbwaser-Klimovsky, D; Alicki, R; Kurizki, G

    2013-01-01

    In traditional thermodynamics the Carnot cycle yields the ideal performance bound of heat engines and refrigerators. We propose and analyze a minimal model of a heat machine that can play a similar role in quantum regimes. The minimal model consists of a single two-level system with periodically modulated energy splitting that is permanently, weakly, coupled to two spectrally separated heat baths at different temperatures. The equation of motion allows us to compute the stationary power and heat currents in the machine consistent with the second law of thermodynamics. This dual-purpose machine can act as either an engine or a refrigerator (heat pump) depending on the modulation rate. In both modes of operation, the maximal Carnot efficiency is reached at zero power. We study the conditions for finite-time optimal performance for several variants of the model. Possible realizations of the model are discussed. PMID:23410316

  5. Simple Machines in the Community

    NSDL National Science Digital Library

    Aris Laroder

    2008-03-01

    The community can be a powerful context and mini-laboratory for cultivating students' common understandings of science and mathematics. On the island of Panay in the Philippines, the community was the starting place for a group of fifth- and sixth-grade students to explore simple machines in their daily lives. What students learned in the process became the basis for developing the set of culturally relevant lessons on simple machines described in this article. Each of the examples that follow features a simple machine found in the community, an explanation of how it works, a guiding-inquiry question, and a follow-up activity designed to foster students' exploration of this question.

  6. Machine learning methods in chemoinformatics

    PubMed Central

    Mitchell, John B O

    2014-01-01

    Machine learning algorithms are generally developed in computer science or adjacent disciplines and find their way into chemical modeling by a process of diffusion. Though particular machine learning methods are popular in chemoinformatics and quantitative structure–activity relationships (QSAR), many others exist in the technical literature. This discussion is methods-based and focused on some algorithms that chemoinformatics researchers frequently use. It makes no claim to be exhaustive. We concentrate on methods for supervised learning, predicting the unknown property values of a test set of instances, usually molecules, based on the known values for a training set. Particularly relevant approaches include Artificial Neural Networks, Random Forest, Support Vector Machine, k-Nearest Neighbors and naïve Bayes classifiers. WIREs Comput Mol Sci 2014, 4:468–481. How to cite this article: WIREs Comput Mol Sci 2014, 4:468–481. doi:10.1002/wcms.1183 PMID:25285160

  7. Coordinate-measuring machine capability

    NASA Astrophysics Data System (ADS)

    Russell, R. J.

    1983-11-01

    Three-axis measuring machines have complex geometric and displacement errors. Many machine users are unaware of these systematic errors and think only in terms of the three-scale or displacement errors which may be significantly smaller in magnitude than the geometric errors. A method of estimating the columetric uncertainty of five coordinate measuring machines (CMMs) was established and the measurement uncertainty is reported for a 20 by 18 by 12 in. work zone. The Latin Square Three Dimensional Ball Plate (LS3DBP) and the Space Master Ball Plate (SMBP) were the volumetric standards selected for the evaluation. Data from each ball plate were transformed into new coordinates and compared to previous calibration or reference data. The deviation between measured and referenced values was recorded. These data were used to determine a quantitative estimate of the CMMs measurement capability in X, Y, and Z space by using the Analysis of Variance Technique (AOV).

  8. Mobile machine hazardous working zone warning system

    SciTech Connect

    Schiffbauer, W.H.; Ganoe, C.W.

    1996-12-31

    A warning system is provided for a mobile working machine to alert an individual of a potentially dangerous condition in the event the individual strays into a hazardous working zone of the machine. The warning system includes a transmitter mounted on the machine and operable to generate a uniform magnetic field projecting beyond an outer periphery of the machine in defining a hazardous working zone around the machine during operation thereof. A receiver, carried by the individual and activated by the magnetic field, provides an alarm signal to alert the individual when he enters the hazardous working zone of the machine.

  9. Machine translation project alternatives analysis

    NASA Technical Reports Server (NTRS)

    Bajis, Catherine J.; Bedford, Denise A. D.

    1993-01-01

    The Machine Translation Project consists of several components, two of which, the Project Plan and the Requirements Analysis, have already been delivered. The Project Plan details the overall rationale, objectives and time-table for the project as a whole. The Requirements Analysis compares a number of available machine translation systems, their capabilities, possible configurations, and costs. The Alternatives Analysis has resulted in a number of conclusions and recommendations to the NASA STI program concerning the acquisition of specific MT systems and related hardware and software.

  10. Exploring Machin's Approximation of Exploring Machin's Approximation of

    E-print Network

    Knaust, Helmut

    #12;Exploring Machin's Approximation of Precursors Method of Exhaustion `a la Archimedes Archimedes of Precursors Method of Exhaustion `a la Archimedes Archimedes of Syracuse ( 287­212 BC) approximated la Archimedes Archimedes of Syracuse ( 287­212 BC) approximated by the Method of Exhaustion: 3

  11. Research on machining error compensation in high-precision surface grinding machine for optical aspheric elements

    NASA Astrophysics Data System (ADS)

    Ke, Xiaolong; Guo, Yinbiao; Zhang, Shihan; Huang, Hao

    2010-10-01

    Using aspheric component in optical system can correct optical aberration, acquire high imaging quality, improve the optical characteristic, simplify system structure, and reduce system volume. Nowadays, high-precision surface grinding machine is an important approach to processing optical aspheric elements. However, because of the characteristics of optical aspheric elements, the processing method makes a higher demand to whole performance of surface grinding machine, and hardly to achieve ideal machining effect. Taking high generality and efficiency into account, this paper presents a compensation method for machining errors of high-precision surface grinding machine, which bases on optical aspheric elements, to achieve high-precision machining for all kinds of optical aspheric elements. After compensation, the machining accuracy of grinding machine could reach 2um/200×200mm. The research bases on NC surface grinding machine which is self developed. First of all, this paper introduces machining principle for optical aspheric elements on the grinding machine. And then error sources which producing errors are analyzed. By contacting and non-contacting measurement sensors, measurement software which is self designed realizes on-position measure for grinded workpiece, then fits surface precision and machining errors. Through compensation software for machining error which is self designed, compensation algorithm is designed and translated compensation data into G-code for the high-precision grinding machine to achieve compensation machining. Finally, by comparison between machining error compensation before and after processing, the experiments for this purpose are done to validate the compensation machining accuracy.

  12. Auditing technology for electronic voting machines

    E-print Network

    Cohen, Sharon B

    2005-01-01

    Direct Recording Electronic (DRE) voting machine security has been a significant topic of contention ever since Diebold voting machine code turned up on a public Internet site in 2003 and computer scientists at Johns Hopkins ...

  13. Auditing Technology for Electronic Voting Machines

    E-print Network

    Cohen, Sharon B.

    2005-05-19

    Direct Recording Electronic (DRE) voting machine security has been a significant topic of contention ever since Diebold voting machine code turned up on a public internet site in 2003 and computer scientists at Johns Hopkins ...

  14. The timely self-portrait machine

    E-print Network

    Haun, Gregory Cosmo

    1992-01-01

    This thesis explores the philosophy which underlies the Timely Self-Portrait Machine. The cultural history of the machine, the phenomenon of Television, and the personal history of this project are discussed. Technical ...

  15. Machine-Aided Indexing for NASA STI.

    ERIC Educational Resources Information Center

    Wilson, John

    1987-01-01

    Describes the use of machine aided indexing as part of NASA's information systems. The discussion covers reasons for incorporating machine aided indexing, the lexical dictionary used, subject switching, natural language processing, benefits to the system, and possible future developments. (CLB)

  16. Using linguistic knowledge in statistical machine translation

    E-print Network

    Zbib, Rabih M. (Rabih Mohamed), 1974-

    2010-01-01

    In this thesis, we present methods for using linguistically motivated information to enhance the performance of statistical machine translation (SMT). One of the advantages of the statistical approach to machine translation ...

  17. Flavors: Message Passing in the Lisp Machine

    E-print Network

    Weinreb, Daniel

    1980-11-01

    The object oriented programming style used in the Smalltalk and Actor languages is available in Lisp Machine Lisp, and used by the Lisp Machine software system. It is used to perform generic operations on objects. Part ...

  18. Low Level Languages for the PAPIA Machine

    Microsoft Academic Search

    O. Catalano; G. di Gaetano; V. di Gesù; G. Gerardi; A. Machì; D. Tegolo

    1986-01-01

    The paper presents the low-level languages implemented up to date to program the PAPIA machine. The parallel assembly-level P-MACRO package, the microcode level instruction set and a machine simulating environment are described.

  19. Human and Machine Intelligence: Comparisons and Contrasts

    ERIC Educational Resources Information Center

    Good, Irving John

    1971-01-01

    Various human mental activities are examined, a theory of brain function presented, and the possible nature of the ultra-intelligent machine" suggested. Some of the social repercussions of such machines are briefly discussed. (AL)

  20. 49 CFR 236.771 - Machine, control.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...Transportation 4 2010-10-01 2010-10-01 false Machine, control. 236.771 Section 236.771 Transportation...SYSTEMS, DEVICES, AND APPLIANCES Definitions § 236.771 Machine, control. An assemblage of manually operated devices...

  1. 49 CFR 236.772 - Machine, interlocking.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...Transportation 4 2011-10-01 2011-10-01 false Machine, interlocking. 236.772 Section 236.772 Transportation...SYSTEMS, DEVICES, AND APPLIANCES Definitions § 236.772 Machine, interlocking. An assemblage of manually operated...

  2. 49 CFR 236.772 - Machine, interlocking.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...Transportation 4 2010-10-01 2010-10-01 false Machine, interlocking. 236.772 Section 236.772 Transportation...SYSTEMS, DEVICES, AND APPLIANCES Definitions § 236.772 Machine, interlocking. An assemblage of manually operated...

  3. 49 CFR 236.771 - Machine, control.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...Transportation 4 2011-10-01 2011-10-01 false Machine, control. 236.771 Section 236.771 Transportation...SYSTEMS, DEVICES, AND APPLIANCES Definitions § 236.771 Machine, control. An assemblage of manually operated devices...

  4. Sequence-invariant state machines

    Microsoft Academic Search

    Sterling R. Whitaker; Shamanna K. Manjunath; Gary K. Maki

    1991-01-01

    A synthesis method and an MOS VLSI architecture are presented to realize sequential circuits that have the ability to implement any state machine having N states and m inputs, regardless of the actual sequence specified in the flow table. The design method utilizes binary tree structured logic to implement regular and dense circuits. The desired state sequence can be hardwired

  5. Sequence-invariant state machines

    Microsoft Academic Search

    Sterling R. Whitaker; Shamanna K. Manjunath; Gary K. Maki

    1991-01-01

    A synthesis method and an MOS VLSI architecture are presented to realize sequential circuits that have the ability to implement any state machine having N states and m inputs, regardless of the actual sequence specified in the flow table. The design method utilizes binary tree structured (BTS) logic to implement regular and dense circuits. The desired state sequence can be

  6. Far Travelers: The Exploring Machines.

    ERIC Educational Resources Information Center

    Nicks, Oran W.

    The National Aeronautics and Space Administration (NASA) program of lunar and planetary exploration produced a flood of scientific information about the moon, planets and the environment of interplanetary space. This book is an account of the people, machines, and the events of this scientific enterprise. It is a story of organizations,…

  7. Basic Machines. Navy Training Course.

    ERIC Educational Resources Information Center

    Bureau of Naval Personnel, Washington, DC.

    This document is a reference for the enlisted men in the Navy whose duties require knowledge of the fundamentals of machinery. Beginning with the simplest of machines--the lever--the book proceeds with the discussion of block and tackle, wheel and axle, inclined plane, screw and gears. It explains the concepts of work and power, and differentiates…

  8. READING MACHINES FOR THE BLIND.

    ERIC Educational Resources Information Center

    FREIBERGER, HOWARD; MURPHY, EUGENE F.

    AT A TECHNICAL SESSION, SIXTY-ONE PARTICIPANTS FROM THE FIELDS OF EDUCATION, INDUSTRY, GOVERNMENT, AND AGENCIES OF THE BLIND DISCUSSED RECENT DEVELOPMENTS IN THE PRODUCTION AND USE OF READING MACHINES WHICH PERMIT BLIND PERSONS GREATER INDEPENDENCE IN READING THE PRINTED PAGE. THEY ALSO EXPLORED PROBLEMS INHERENT IN THESE EFFORTS AND PROPOSED…

  9. Constructing support vector machine ensemble

    Microsoft Academic Search

    Hyun-chul Kim; Shaoning Pang; Hong-mo Je; Daijin Kim; Sung Yang Bang

    2003-01-01

    Even the support vector machine (SVM) has been proposed to provide a good generalization performance, the classi6cation result of the practically implemented SVM is often far from the theoretically expected level because their implementations are based on the approximated algorithms due to the high complexity of time and space. To improve the limited classi6cation performance of the real SVM, we

  10. Multilingual lexicons for machine translation

    Microsoft Academic Search

    Lim Lian Tze

    2009-01-01

    Despite the numerous bad press received by machine translation systems, they are invaluable in aiding users to quickly gather the essence of texts written in an unfamiliar language, particularly on the Web. Sufficiently accurate translation of lexical items is essential to satisfy such needs. Lexicon resources, especially a well-designed multilingual lexicon is needed to facilitate effective translation selection of lexical

  11. Underwater cold tap machine tested

    SciTech Connect

    Not Available

    1985-05-01

    Tests are complete on a strategic cold tap machine for underwater lines. The system was designed around Total's Norway-UK Frigg gas line. It provides a permanent, easily mobilized, mechanical insurance against damage to the Frigg line but also provides a proven, workable principle for the repair or modification of other lines. The design of the system is discussed.

  12. Machine translation using isomorphic UCGs

    Microsoft Academic Search

    John L. Beaven; Pete Whitelock

    1988-01-01

    This paper discusses the application of Unification Categorial Grammar (UCG) to the framework of Isomorphic Grammars for Machine Translation pioneered by Landsbergen. The Isomorphic Grammars approach to MT involves developing the grammars of the Source and Target languages in parallel, in order to ensure that SL and TL expressions which stand in the translation relation have isomorphic derivations. The principle

  13. Electrochemical Machining Carves out Nanostructures

    NSDL National Science Digital Library

    Kalaugher, Liz

    This news article from June 20, 2003 published by Great Britain's Institute of Physics, describes an electrochemical machining process that is being used to fabricate complex nanostructures. The work, produced by German and U.S. researchers, has the potential to compete with current lithographic processes.

  14. The architecture of lisp machines

    SciTech Connect

    Pleszkun, A.R.; Thazhuthaveetil, M.J.

    1987-03-01

    Lisp has been a popular programming language for well over 20 years and has become the premier language of artificial intelligence research. Recent interest in fifth generation computer systems has sparked renewed interest in systems for the efficient execution of Lisp and Lisp-like languages. There are two main reasons for Lisp's popularity: extensibility and flexibility. Lisp's extensibility derives from the capability that it provides to build powerful, friendly systems starting with just a few basic primitives and data types. Lisp is dynamically typed and ideally suited for incremental program development, making it a good choice for the fast prototyping of software systems. Several current symbolic manipulation and algebraic systems, design and graphic description systems, expert systems, and other heavily-used non-numeric systems are also based on an underlying Lisp system. Typically, these systems do not run efficiently due to the large semantic gap between list-manipulating languages like Lisp and the conventional von Neumann machine. In this survey, the authors the author discuss what takes place during typical Lisp execution. Based on this, the authors enumerate the runtime requirements of a Lisp system and identify potential obstacles to good machine performance. The authors provide a classification of the Lisp machines that they encountered during the survey, and examine the techniques employed in these machines to cater to Lisp's runtime requirements.

  15. Simple pulse asynchronous state machines

    Microsoft Academic Search

    Jeffrey Miller; Woodward Yang

    1996-01-01

    Pulse computation is a hybrid of conventional analog and digital techniques which encodes and processes information in the time domain. In this paper we present a new technique for pulse computation with simple pulse-driven, asynchronous finite state machines. Asynchronous FSMs are robust and timescale-independent, and can be used as building blocks for constructing complex pulse processors. The notion of state

  16. Machine Tool Operation, Course Description.

    ERIC Educational Resources Information Center

    Denny, Walter E.; Anderson, Floyd L.

    Prepared by an instructor and curriculum specialists, this course of study was designed to meet the individual needs of the dropout and/or hard-core unemployed youth by providing them skill training, related information, and supportive services knowledge in machine tool operation. The achievement level of each student is determined at entry, and…

  17. Precision Machining Technology. Curriculum Guide.

    ERIC Educational Resources Information Center

    Idaho State Dept. of Education, Boise. Div. of Vocational Education.

    This curriculum guide was developed from a Technical Committee Report prepared with the assistance of industry personnel and containing a Task List which is the basis of the guide. It presents competency-based program standards for courses in precision machining technology and is part of the Idaho Vocational Curriculum Guide Project, a cooperative…

  18. Machine Shop. Student Learning Guide.

    ERIC Educational Resources Information Center

    Palm Beach County Board of Public Instruction, West Palm Beach, FL.

    This student learning guide contains eight modules for completing a course in machine shop. It is designed especially for use in Palm Beach County, Florida. Each module covers one task, and consists of a purpose, performance objective, enabling objectives, learning activities and resources, information sheets, student self-check with answer key,…

  19. Anisotropy of machine building materials

    NASA Technical Reports Server (NTRS)

    Ashkenazi, Y. K.

    1981-01-01

    The results of experimental studies of the anisotropy of elastic and strength characteristics of various structural materials, including pressure worked metals and alloys, laminated fiberglass plastics, and laminated wood plastics, are correlated and classified. Strength criteria under simple and complex stresses are considered as applied to anisotropic materials. Practical application to determining the strength of machine parts and structural materials is discussed.

  20. Bias and Variance Machine Learning

    E-print Network

    Wehenkel, Louis

    Bias and Variance in Machine Learning Pierre Geurts Université de Liège Octobre 2002 #12;2 Content techniques · Decision tree induction #12;3 Content of the presentation · Bias and variance definitions · Decision tree induction #12;4 Regression problem - no input · Goal: predict as well as possible the height

  1. Miniature Gas-Circulating Machine

    NASA Technical Reports Server (NTRS)

    Swift, Walter L.; Valenzuela, Javier A.; Sixsmith, Herbert; Nutt, William E.

    1993-01-01

    Proposed gas-circulating machine consists essentially of centrifugal pump driven by induction motor. Noncontact bearings suppress wear and contamination. Used to circulate helium (or possibly hydrogen or another gas) in regeneration sorption-compressor refrigeration system aboard spacecraft. Also proves useful in terrestrial applications in which long life, reliability, and low contamination essential.

  2. Dimensioning, Tolerancing, and Machine Finishes.

    ERIC Educational Resources Information Center

    Adams, George C.

    Intended for use with the vocational education student interested in technical drawing, this guide provides answers to questions relating to dimensioning and tolerancing machine drawings. It also gives examples of standard dimensioning practices, tolerancing applications, and finish applications. The problems and examples presented are based on…

  3. Editorial: Human and Machine Learning

    Microsoft Academic Search

    Pat Langley

    1986-01-01

    Although science can be characterized in terms of search, some search methods let one explore multiple paths in parallel. We have argued that more machine learning researchers should focus their efforts on modeling human behavior, but we have not argued that the field should limit itself to this approach. For those interested in general principles, the study of nonhuman learning

  4. Eigenvalue analysis of synchronous machines

    Microsoft Academic Search

    R. J. Kuhler; V. J. Watson

    1975-01-01

    This paper presents a numerical approach useful for determining the modes of transient response of a synchronous generator. The approach is based upon the Floquet theory of periodic time-variable systems. A computer algorithm for system transition matrix eigenvalue analysis is described and applied to a three-phase synchronous machine.

  5. Computed Tomography Measuring Inside Machines

    NASA Technical Reports Server (NTRS)

    Wozniak, James F.; Scudder, Henry J.; Anders, Jeffrey E.

    1995-01-01

    Computed tomography applied to obtain approximate measurements of radial distances from centerline of turbopump to leading edges of diffuser vanes in turbopump. Use of computed tomography has significance beyond turbopump application: example of general concept of measuring internal dimensions of assembly of parts without having to perform time-consuming task of taking assembly apart and measuring internal parts on coordinate-measuring machine.

  6. Wormholes and Time-Machines

    E-print Network

    Frank Antonsen; Karsten Bormann

    1996-08-28

    It has been proposed that wormholes can be made to function as time-machines. This opens up the question of whether this can be accomodated within a self-consistent physics or not. In this contribution we present some quantum mechanical considerations in this respect.

  7. Jure Leskovec Machine Learning Department

    E-print Network

    Pratt, Vaughan

    Jure Leskovec Machine Learning Department Carnegie Mellon University Thesis defense, September 3PapadimitriouSaberi `06], Hubs and authorities [Page et al. '98, Kleinberg `99] Models: Preferential attachment [Barabasi '99], Small world [WattsStrogatz `98], Copying model [Kleinberg el al. '99], Heuristically optimized

  8. Active Support Vector Machine Classification

    Microsoft Academic Search

    Olvi L. Mangasarian; David R. Musicant

    2000-01-01

    An active set strategy is applied to the dual of a simple reformula- tion of the standard quadratic program of a linear support vector machine. This application generates a fast new dual algorithm that consists of solving a finite number of linear equations, with a typically large dimensionality equal to the number of points to be classified. However, by making

  9. Proximal support vector machine classifiers

    Microsoft Academic Search

    Glenn Fung; Olvi L. Mangasarian

    2001-01-01

    Instead of a standard support vector machine (SVM) that classifies points by assigning them to one of two disjoint half-spaces, points are classified by assigning them to the closest of two parallel planes (in input or feature space) that are pushed apart as far as possible. This formulation, which can also be interpreted as regularized least squares and considered in

  10. Com1005: Machines and Intelligence

    E-print Network

    Sharkey, Amanda

    Com1005: Machines and Intelligence Amanda Sharkey Friday, 19 October 2012 #12;Last week .... Friday' is a stack that contains two green cubes and a pyramid. Friday, 19 October 2012 #12;} But Shrdlu's knowledge' } A `steeple' is a stack that contains two green cubes and a pyramid. } I UNDERSTAND Friday, 19 October 2012

  11. Learning and Evaluating Boltzmann Machines

    Microsoft Academic Search

    Ruslan Salakhutdinov

    2008-01-01

    We provide a brief overview of the variational framework for obtaining determinis- tic approximations or upper bounds for the log-partition function. We also review some of the Monte Carlo based methods for estimating partition functions of arbi- trary Markov Random Fields. We then develop an annealed importance sampling (AIS) procedure for estimating partition functions of rest ricted Boltzmann machines (RBM's),

  12. Permutation parity machines for neural cryptography

    SciTech Connect

    Reyes, Oscar Mauricio [Institute of Computer Technology, Hamburg University of Technology, D-21071 Hamburg (Germany); Escuela de Ingenieria Electrica, Electronica y Telecomunicaciones, Universidad Industrial de Santander, Bucaramanga (Colombia); Zimmermann, Karl-Heinz [Institute of Computer Technology, Hamburg University of Technology, D-21071 Hamburg (Germany)

    2010-06-15

    Recently, synchronization was proved for permutation parity machines, multilayer feed-forward neural networks proposed as a binary variant of the tree parity machines. This ability was already used in the case of tree parity machines to introduce a key-exchange protocol. In this paper, a protocol based on permutation parity machines is proposed and its performance against common attacks (simple, geometric, majority and genetic) is studied.

  13. 09s1: COMP9417 Machine Learning and Data Mining Machine Learning for Numeric

    E-print Network

    Bain, Mike

    09s1: COMP9417 Machine Learning and Data Mining Machine Learning for Numeric Prediction April 1, 2009 Acknowledgement: Material derived from slides for the book Machine Learning, Tom M. Mitchell, Mc by John Wiley & Sons, Inc. Aims This lecture will enable you to describe and reproduce machine learning

  14. 09s1: COMP9417 Machine Learning and Data Mining Introduction to Machine Learning

    E-print Network

    Bain, Mike

    09s1: COMP9417 Machine Learning and Data Mining Introduction to Machine Learning March 12, 2008 Acknowledgement: Material derived from slides for the book Machine Learning, Tom Mitchell, McGraw-Hill, 1997 http to describe the motivation, scope and some application areas of machine learning. Following it you should

  15. Eclipse-RP: a new RP machine based on repeated deposition and machining

    E-print Network

    Kim, Jongwon

    Eclipse-RP: a new RP machine based on repeated deposition and machining J Kim*, K S Cho, J C Hwang of this machine is based on the Eclipse parallel mechanism invented by the authors. One of the advantages of the Eclipse mechanism as compared to Gough­Stewart-based parallel mechanisms and applied to machining

  16. Combining Psychological Models with Machine Learning 1 Running head: COMBINING PSYCHOLOGICAL MODELS WITH MACHINE LEARNING

    E-print Network

    Kraus, Sarit

    's behavior. At the forefront of these types of methods are various machine learning algorithms. This paperCombining Psychological Models with Machine Learning 1 Running head: COMBINING PSYCHOLOGICAL MODELS WITH MACHINE LEARNING Combining Psychological Models with Machine Learning to Better Predict People's Decisions

  17. International Conference on Machine Control & Guidance 2008 1 Use of a Machine Control & Guidance System, Deter-

    E-print Network

    1st International Conference on Machine Control & Guidance 2008 1 Use of a Machine Control and surveyors [w.a.07]. This development should be kept in mind when training students. 1.1 History complicated machine for machine control applications. Possi- bilities to improve the productivity are

  18. A virtual machine concept for real-time simulation of machine tool dynamics

    Microsoft Academic Search

    Anders Jönsson; Johan Wall; Göran Broman

    2005-01-01

    When designing CNC machine tools it is important to consider the dynamics of the control, the electrical components and the mechanical structure of the machine simultaneously. This paper describes the structure and implementation of a concept for real-time simulation of such machine tools using a water jet cutting machine as an application. The concept includes a real control system, simulation

  19. Electrical Discharge Machining (EDM) Characteristics Associated with Electrical Discharge Energy on Machining of Cemented Tungsten Carbide

    Microsoft Academic Search

    Yan-Cherng Lin; Yuan-Feng Chen; Ching-Tien Lin; Hsinn-Jyh Tzeng

    2008-01-01

    In this investigation, cemented tungsten carbides graded K10 and P10 were machined by electrical discharge machining (EDM) using an electrolytic copper electrode. The machining parameters of EDM were varied to explore the effects of electrical discharge energy on the machining characteristics, such as material removal rate (MRR), electrode wear rate (EWR), and surface roughness. Moreover, the effects of the electrical

  20. Machine Learning Algorithms for Cancer Diagnosis Abraham Karplus

    E-print Network

    Karplus, Kevin

    Machine Learning Algorithms for Cancer Diagnosis Abraham Karplus Santa Cruz County Science Fair . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 Machine Learning 5 Testing Methods. The eventual goal of machine learning in cancer diagnosis is to have a trained machine learning algorithm that

  1. Using machine learning techniques to interpret results from discrete event

    E-print Network

    Mladenic, Dunja

    Using machine learning techniques to interpret results from discrete event simulation Dunja Mladeni machine learning techniques. The results of two simulators were processed as machine learning problems discovered. Key words: discrete event simulation, machine learning, artificial intelligence 1 Introduction

  2. 29 CFR 1910.212 - General requirements for all machines.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... false General requirements for all machines. 1910.212 Section 1910.212...AND HEALTH STANDARDS Machinery and Machine Guarding § 1910.212 General requirements for all machines. (a) Machine guarding...

  3. 29 CFR 1910.212 - General requirements for all machines.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... false General requirements for all machines. 1910.212 Section 1910.212...AND HEALTH STANDARDS Machinery and Machine Guarding § 1910.212 General requirements for all machines. (a) Machine guarding...

  4. Evaluation of an improved centrifugal casting machine.

    PubMed

    Donovan, T E; White, L E

    1985-05-01

    A Type III gold alloy, a silver-palladium alloy, and a base metal alloy were cast in two different centrifugal casting machines. With the number of complete cast mesh squares as an indicator of castability, the Airspin casting machine produced superior castings with all three alloys. The base metal alloy produced the greatest number of complete squares with both casting machines. PMID:3889295

  5. Turkish To Crimean Tatar Machine Translation System

    Microsoft Academic Search

    Kemal Altintas

    2001-01-01

    TURKISH TO CRIMEAN TATAR MACHINE TRANSLATION SYSTEM Kemal Altintas MS in Computer Engineering Supervisor: Asst.Prof.Ilyas Cicekli July, 2001 Machine translation has always been interesting to people since the invention of computers. Most of the research has been conducted on western languages such as English and French, and Turkish and Turkic languages have been left out of the scene. Machine translation

  6. E4 --Machine Learning Pedro Domingos

    E-print Network

    Anderson, Richard

    E4 -- Machine Learning Pedro Domingos Department of Computer Science & Engineering University-543-2969 Abstract Machine learning's focus on ill-defined problems and highly flexible methods makes it ideally suited for KDD applications. Among the ideas machine learning contributes to KDD are the importance

  7. Machine Learning for Signature Verification Harish Srinivasan

    E-print Network

    Machine Learning for Signature Verification Harish Srinivasan , Sargur N. Srihari and Matthew J it can be viewed as one that involves machine learning from a population of signatures. There are two and performance phases is de- scribed. Keywords: machine learning, forensic signature examination, biometrics

  8. Ph.D. Program in Machine Learning

    E-print Network

    Page 1 Ph.D. Program in Machine Learning Student Handbook Revised 7/20/12 #12;Page 2 Table Machine Learning Journal Club...................................................................................................17 #12;Page 3 Introduction The field of machine learning is concerned with the question of how

  9. Learning with kernel machine architectures Theodoros Evgeniou

    E-print Network

    Poggio, Tomaso

    Learning with kernel machine architectures by Theodoros Evgeniou B.S. Massachusetts Institute by . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Arthur C. Smith Chairman, Departmental Committee on Graduate Students #12;Learning with kernel machine Abstract This thesis studies the problem of supervised learning using a family of machines, namely kernel

  10. HAPTICS-AUGMENTED SIMPLE MACHINES EDUCATIONAL TOOLS

    Microsoft Academic Search

    Robert L. Williams; Meng-Yun Chen; Jeffrey M. Seaton

    This article describes a unique project using commercial haptic interfaces to augment the teaching of simple machines in elementary school. Haptic interfaces provide the sense of touch and force to the human from a virtual model on the computer. Since force is central to the teaching of simple machines, we believe that the use of haptics in virtual simple machines

  11. Machine Aid for Switching Circuit Design

    Microsoft Academic Search

    Claude Shannon; Edward Moore

    1953-01-01

    The design of circuits composed of logical elements may be facilitated by auxiliary machines. This paper describes one such machine, made of relays, selector switches, gas diodes, and germanium diodes. This machine (called the relay circuit analyzer) has as inputs both a relay contact circuit and the specifications the circuit is expected to satisfy. The analyzer (1) verifies whether the

  12. LARGESCALE MACHINE TRANSLATION: AN INTERLINGUA APPROACH

    E-print Network

    Shamos, Michael I.

    be user information for consumer electronics. 2.1 The Knowledge Base Successful translation by machine requires the use of vari­ ous types of knowledge (hence the term ``Knowledge­Based Machine TranslationLARGE­SCALE MACHINE TRANSLATION: AN INTERLINGUA APPROACH Deryle W. Lonsdale, Alexander M. Franz

  13. Effects of machine translation on collaborative work

    Microsoft Academic Search

    Naomi Yamashita; Toru Ishida

    2006-01-01

    Even though multilingual communities that use machine translation to overcome language barriers are increasing, we still lack a complete understanding of how machine translation affects communication. In this study, eight pairs from three different language communities-China, Korea, and Japan-worked on referential tasks in their shared second language (English) and in their native languages using a machine translation embedded chat system.

  14. What is Example-Based Machine Translation?

    Microsoft Academic Search

    Davide Turcato; Fred Popowich

    2003-01-01

    We maintain that the essential feature that characterizes a Machine Translation approach and sets it apart from other approaches is the kind of knowledge it uses. From this perspective, we argue that Example-Based Machine Translation is sometimes characterized in terms of inessential features. We show that Example-Based Machine Translation, as long as it is linguistically principled, significantly overlaps with other

  15. Machine Translation Overview Language Technologies Institute

    E-print Network

    Lavie, Alon

    Machine Translation Overview Alon Lavie Language Technologies Institute Carnegie Mellon University LTI Immigration Course August 22, 2011 #12;August 22, 2011 LTI IC 2011 2 Machine Translation: History for Machine Translation" (CMT) founded · Late 1980s and early 1990s: Field dominated by rule-based approaches

  16. Conditions of proper sculptured surface machining

    Microsoft Academic Search

    Stephen P. Radzevich

    2002-01-01

    Multi-axis machining of sculptured surfaces is in wide use in Conventional and Rapid Prototyping. Topic of the paper is in the area of sculptured surface machining (SSM). The problem under consideration is: how to define and how to analytically describe a set of necessary and sufficient conditions of proper SSM. The similar problem is already solved with respect to machining

  17. Preliminary study of high-speed machining

    SciTech Connect

    Jordan, R.E.

    1980-07-01

    The feasibility of a high speed machining process has been established for application to Bendix aluminum products, based upon information gained through visits to existing high speed machining facilities and by the completion of a representative Bendix part using this process. The need for an experimental high speed machining capability at Bendix for further process evaluation is established.

  18. Application of Fractal in Machine Downtime Control

    Microsoft Academic Search

    Xuanxuan Li; Bo Li; Limei Xu; Sean Li

    2007-01-01

    Unexpected machine failures directly impact machine availability, which leads to phantom capacity, high maintenance cost, and risks to factory profitability and competitiveness. The collateral damage far exceeds the original downtime itself. This paper proposes a fractal based method for machine downtime trend analysis and performance control. AR (Auto Regression) model is applied for data pre-process, rescaled range (R\\/S) analysis and

  19. Refinement Transformation Using Abstract Parallel Machines

    E-print Network

    Goodman, Joy

    for circuit specification--- `concrete parallel machines'. #12; The ability to define Abstract ParallelRefinement Transformation Using Abstract Parallel Machines Joy Goodman 1 , John O'Donnell 1 and Gudula R¨unger 2 1 University of Glasgow 2 Universit¨at Leipzig Abstract. Abstract Parallel Machines

  20. Machining of aluminium based metal matrix composites

    Microsoft Academic Search

    S. Barnes; I. R. Pashby

    1995-01-01

    Although metal matrix composites (MMCs) are generally regarded as extremely difficult to machine, it is also acknowledged that their machining behaviour is not fully understood. The work reviewed here confirms this widely held view but also suggests that the machinability of these materials can be improved by appropriate selection of the reinforcing phase, its volume fraction, size, and morphology as

  1. PRE-MACHINING CNC CONTOUR VALIDATION

    Microsoft Academic Search

    Tony Schmitz; John Ziegert

    The current procedure followed to manufacture a new part by CNC machining is to write the part program, machine a test part and measure the test part for conformance to the required dimensions and tolerances. If the test part dimensions are not correct, the part program is modified and the process repeated until a successful part is machined. In many

  2. THE FIRST BOOK OF TEACHING MACHINES.

    ERIC Educational Resources Information Center

    EPSTEIN, SAM; EPSTEIN, BERYL

    THE FIRST TEACHING MACHINE WAS INVENTED IN THE 1920'S BY SIDNEY L. PRESSEY AND THE FIRST MODERN TEACHING MACHINE WAS DEVELOPED AND POPULARIZED IN THE EARLY 1930'S BY B.F. SKINNER. TODAY BUSINESSMEN AND INDUSTRIALISTS AS WELL AS EDUCATORS HAVE FOUND TEACHING MACHINES USEFUL. ACTUALLY, TEACHING IS ACCOMPLISHED THROUGH THE PROGRAM, A CAREFULLY…

  3. Stability Analysis of a Symmetrical Induction Machine

    Microsoft Academic Search

    ROBERT H. NELSON; THOMAS A. LIPO; PAUL C. KRAUSE

    1969-01-01

    A stability study of an induction machine is performed by applying the root-locus criterion to the equations which describe the behavior of the machine during small displacements about a steady-state operating point. This investigation reveals that a symmetrical induction machine may become unstable at low speeds (low frequencies) even though balanced, constant amplitude, sinusoidal voltages are applied to the stator

  4. Multiple coupled circuit modeling of induction machines

    Microsoft Academic Search

    Xiaogang Luo; Yuefeng Liao; H. A. Toliyat; A. El-Antably; T.A. Lipo

    1995-01-01

    A new multiple coupled circuit model is presented for simulation of induction machines with both arbitrary winding layout and\\/or unbalanced operating conditions. The model is derived by means of winding functions. No symmetry is assumed. The parameters of the model are calculated directly from the geometry and winding layout of the machine. The behavior of an induction machine during starting

  5. Teaching Machine Learning to Design Students

    Microsoft Academic Search

    Bram Van Der Vlist; Rick Van De Westelaken; Christoph Bartneck; Jun Hu; René M. C. Ahn; Emilia I. Barakova; Frank Delbressine; Loe M. G. Feijs

    2008-01-01

    Machine learning is a key technology to design and create intelligent systems, products, and related services. Like many other design departments, we are faced with the challenge to teach machine learning to design students, who often do not have an inherent affinity towards technology. We successfully used the Embodied Intelligence method to teach machine learning to our students. By embodying

  6. Machine Learning for the System Administrator

    Microsoft Academic Search

    Marc Chiarini; Alva Couch

    2007-01-01

    In this paper, we explore how some of the principal ideas in machine learning can be applied to the specic task of monitoring computer systems. We show that machine learning can be a valuable tool for accomplishing everyday administrative tasks, and a worthy addition to the arsenal of tools utilized by the system administrator. Difficulties in utilizing machine learning do

  7. Measure Transformer Semantics for Bayesian Machine Learning

    E-print Network

    Plotkin, Joshua B.

    Measure Transformer Semantics for Bayesian Machine Learning Johannes Borgstr¨om1, Andrew D. Gordon1 of Pennsylvania Abstract. The Bayesian approach to machine learning amounts to inferring pos- terior distributions distribution) and a set of observations of vari- ables. There is a trend in machine learning towards expressing

  8. Magnetic properties in double star induction machine

    Microsoft Academic Search

    H. Hammache; D. Moussaoui; K. Marouani; T. Hamdouche

    2008-01-01

    Multiphase machines are getting increasingly common in electric traction. The prediction of the losses in multiphase machine is a fundamental step for the optimization of its design. The present paper deals with an experimental study of the behavior of the losses observed in double star induction machines (DSIM). We suggest a study of the losses through the measurements of the

  9. Machining Channels on Mesoscale Ceramic Components

    Microsoft Academic Search

    H.-W. Shin; P. Kwon; C. K. Kok; E. Case

    2004-01-01

    Compaction of ceramic powder, partial sintering, machining, sintering of the ceramic compact, and finally joining are used to form functional channels on mesoscale ceramic components. This paper reports on a new simple machining technique that has been developed to introduce channels. Because no binder phase is used and the partially sintered powder is readily machinable, this technique is easier and

  10. Machine Code Programming in the Physics Laboratory.

    ERIC Educational Resources Information Center

    Wilson, R. J.

    1984-01-01

    A BASIC computer program was written for an experiment that measures the time of a fall of a ball-bearing dropped through a measured distance. However, the timing subroutine was written in machine language. The reason for using machine language, the machine language program, hardware used, and the experiment are discussed. (JN)

  11. Model checking UML state machines and collaborations

    Microsoft Academic Search

    Timm Schäfer; Alexander Knapp; Stephan Merz

    2001-01-01

    The Unified Modeling Language provides two complementary notations, state machines and collaborations, for the specification of dynamic system behavior. We describe a proto-type tool, HUGO, that is designed to automatically verify whether the interactions expressed by a collaboration can indeed be realized by a set of state machines. We compile state machines into a PROMELA model and collaborations into sets

  12. Getting Started with Microsoft Azure Virtual Machines

    E-print Network

    Narasayya, Vivek

    location to location with a tablet and then connect to a virtual machine using RDP or SSH to access yourGetting Started with Microsoft Azure Virtual Machines Introduction You can use a Microsoft Azure Virtual Machine when you need a scalable, cloud-based server running a Windows or Linux operating system

  13. Torque Angle Loop Analysis of Synchronous Machines

    Microsoft Academic Search

    A. S. Gopala Rao; D. Thukaram; B. S. Ramakrishna Iyengar

    1986-01-01

    This paper reports the dynamic stability analysis of a single machine infinite bus system through torque angle loop analysis and forms an extension of the work on Block diagrams and torque angle loop analysis of synchronous machines reported by I. Nagy [3]. It aims to incorporate in the machine model, the damper windings (one on each axis) and to compare

  14. New Measurement of Synchronous Machine Quantities

    Microsoft Academic Search

    Hiroshi Kaminosono; Kiyotaka Uyeda

    1968-01-01

    Synchronous machine quantities are used in the various studies of power system behavior under both normal and abnormal conditions. Instead of the IEEE test code 115 [1] generally employed, this paper describes two approaches to measure synchronous machine quantities of each winding with the machine at standstill, namely, the indicial response method and the low-requency response method. These quantities are

  15. Synchronous Machine Modeling 1.0 Introduction

    E-print Network

    McCalley, James D.

    in a position to understand synchronous machine modeling for power system dynamic analysis. If you take EE 457Synchronous Machine Modeling 1.0 Introduction Our motivation at this point is to put you to synchronous machine models. But I hope to improve on this with these notes. Please read both. One last comment

  16. Compiler Support for MachineIndependent

    E-print Network

    Tseng, Chau-Wen

    distributed­memory machine. Issues addressed include data decomposition analysis, guard introduc­ tion­ itives for distributed­memory machines or multidimen­ sional vector operations for synchronous dataCompiler Support for Machine­Independent Parallel Programming in Fortran D Seema Hiranandani Ken

  17. ANALYSIS OF THE INTERFERENCE SYNCHRONOUS MACHINE

    Microsoft Academic Search

    E. ANDRESEN

    1978-01-01

    Interference synchronous machines operate at different speeds of the fundamental air gap field and of the rotor, because the fundamental permeance wave is produced by interference of open stator and rotor slots the numbers of which being slightly different. In the literature different names are used for this remarkable electrical machine (“Synchronous inductor motor”, “Vernier reluctance motor”). Interference synchronous machines

  18. Machining of fiber-reinforced composite laminates

    Microsoft Academic Search

    Myong-Shik Won

    1999-01-01

    As fiber-reinforced composite laminates are becoming considerably popular in a wide range of applications, the necessity for machining such materials is increasing rapidly. Due to their microscopical inhomogeneity, anisotropy, and highly abrasive nature, composite laminates exhibit some peculiar types of machining damage. Consequently, the machining of composite laminates requires a different approach from that used for metals and offers a

  19. Automatic Data Layout Distributed Memory Machines

    E-print Network

    Kremer, Ulrich

    Automatic Data Layout for Distributed Memory Machines Ulrich Kremer CRPC­TR95­559­S October, 1995­1892 #12; RICE UNIVERSITY Automatic Data Layout for Distributed Memory Machines by Ulrich Kremer A Thesis Data Layout for Distributed Memory Machines Ulrich Kremer Abstract The goal of languages like Fortran D

  20. Infinite Time Register Machines Peter Koepke

    E-print Network

    Koepke, Peter

    Infinite Time Register Machines Peter Koepke University of Bonn Mathematisches Institut BeringstraÃ?e 1 D 53115 Bonn Germany Koepke@Math.Uni-Bonn.de Abstract. Infinite time register machines (ITRMs time Turing ma- chines (ITTMs) by letting an ordinary Turing machine run for arbitrarily many ordinal