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1

21 CFR 870.4220 - Cardiopulmonary bypass heart-lung machine console.  

Code of Federal Regulations, 2010 CFR

...2010-04-01 false Cardiopulmonary bypass heart-lung machine console. 870.4220... § 870.4220 Cardiopulmonary bypass heart-lung machine console. (a) Identification. A cardiopulmonary bypass heart-lung machine console is a device...

2010-04-01

2

21 CFR 870.4220 - Cardiopulmonary bypass heart-lung machine console.  

Code of Federal Regulations, 2011 CFR

... false Cardiopulmonary bypass heart-lung machine console. 870.4220 Section...4220 Cardiopulmonary bypass heart-lung machine console. (a) Identification. A cardiopulmonary bypass heart-lung machine console is a device that...

2011-04-01

3

21 CFR 870.4220 - Cardiopulmonary bypass heart-lung machine console.  

Code of Federal Regulations, 2014 CFR

... false Cardiopulmonary bypass heart-lung machine console. 870.4220 Section...4220 Cardiopulmonary bypass heart-lung machine console. (a) Identification. A cardiopulmonary bypass heart-lung machine console is a device that...

2014-04-01

4

21 CFR 870.4220 - Cardiopulmonary bypass heart-lung machine console.  

Code of Federal Regulations, 2013 CFR

... false Cardiopulmonary bypass heart-lung machine console. 870.4220 Section...4220 Cardiopulmonary bypass heart-lung machine console. (a) Identification. A cardiopulmonary bypass heart-lung machine console is a device that...

2013-04-01

5

21 CFR 870.4220 - Cardiopulmonary bypass heart-lung machine console.  

Code of Federal Regulations, 2012 CFR

... false Cardiopulmonary bypass heart-lung machine console. 870.4220 Section...4220 Cardiopulmonary bypass heart-lung machine console. (a) Identification. A cardiopulmonary bypass heart-lung machine console is a device that...

2012-04-01

6

Perfusion of isolated organs and the first heart-lung machine.  

PubMed

In 1885, Max von Frey (1852-1932), while working in Carl Ludwig's Physiological Institute in Leipzig, Germany, designed an apparatus that had criteria characteristic of a heart-lung machine. With this device, he perfused the entire lower extremity of dogs, and took measurements of oxygen consumption, and carbon dioxide and lactate production. In 1935, another type of perfusion apparatus was constructed by Charles A Lindbergh (1902-1973). This device was the result of cooperation with Alexis Carrel (1873-1944) who was a pioneer of experimental organ transplantation. Using Lindbergh's pulsating device, organs such as thyroid, ovary, suprarenal gland, spleen, heart and kidney from fowls and cats were perfused with an oxygenated medium, and were maintained under sterile conditions. Beginning in 1934, John H Gibbon (1903-1973) developed and tested a heart-lung machine to institute cardiopulmonary bypass in cats during experimental occlusion of the pulmonary artery. In 1953, he performed the first successful open-heart operation in a patient using a heart-lung machine. This included elements that were similar to those used by von Frey - ie, the oxygenator and the pumps for continuous circulation of blood. A comparison of the three experimental devices revealed the following: the application for experimental purposes preceded clinical use; the development shifted from Europe to the United States, and was achieved by people who were not specialists; and the intention to build such a device was first purely scientific interest, but later shifted to the care for and treatment of patients with heart and circulatory defects by open-heart surgery. PMID:11586387

Zimmer, H G

2001-09-01

7

Development of a rabbit animal model for miniaturized heart-lung machines.  

PubMed

The utilization of a heart-lung machine (HLM) for the correction of congenital heart defects can lead to various complications, which can culminate in multiorgan failure and death. To reduce the considerable risk of complications, we developed a miniaturized, highly integrated HLM (MiniHLM) for use in infants and children. For the purpose of testing the MiniHLM, we developed a new rabbit animal model. In all, surgery was performed on 32 rabbits. In the first series, 13 New Zealand white rabbits were placed on cardiopulmonary bypass (CPB) for 1 hour with the use of an initial version of the MiniHLM. In the second series, we operated on 19 Chinchilla Bastard rabbits using the further developed MiniHLM 02 or the Dideco Kids D100 system. While several adjustments had to be made to the operating protocol in the first series in order to lower the mortality rate, 15 of the 19 rabbits were successfully weaned from the HLM in the second series. Blood tests pertaining to hemolysis and the expression of inflammation were performed. In addition, tissue samples were taken from the right atrial auricle for the purpose of investigating the expression of inflammatory parameters. The newly developed MiniHLM prototype was tested successfully in an animal model in terms of technical function, hemolysis, and the expression of inflammation. On account of the comparability of their blood values, as well as their anatomy, Chinchilla Bastard rabbits serve as excellent models for the testing of CPB and support systems for infants and children that do not require the administration of foreign blood. PMID:23438778

Schnoering, Heike; Arens, Jutta; Detering, Sabine M; Stopinski, Tadek; Kuschel, Tarah J; Tolba, Rene; Steinseifer, Ulrich; Vazquez-Jimenez, Jaime F

2013-01-01

8

A newly developed miniaturized heart-lung machine--expression of inflammation in a small animal model.  

PubMed

Cardiopulmonary bypass may cause severe inflammatory reactions and multiorgan failure, especially in premature and low-weight infants. This is due in part to the large area of contact with extrinsic surfaces and the essential addition of foreign blood. Thus, we developed a new miniaturized heart-lung machine (MiniHLM) with a total static priming volume of 102mL (including arterial and venous lines) and tested it in a small animal model. Seven Chinchilla Bastard rabbits were perfused with the MiniHLM (dynamic priming volume 127mL). Seven animals serving as a control were perfused using Dideco Kids and a Stöckert roller pump (modified dynamic priming volume 149mL). The rabbits were anesthetized and sternotomized, followed by cannulation of the aorta and the right atrium. The aorta was clamped for 1h. Blood for examination of inflammation (TNF-?, IL-1?, IL-6, IL-8, and IL-10) and blood gas analysis were taken before skin incision, 5min before opening of the aorta, 15min after opening of the aorta, and 4?h after the initiation of cardiopulmonary bypass. The parameters of inflammation were expressed by means of the comparative C(T) method (??C(T) method). After gradual reduction of perfusion with the HLM, the heart was decannulated, and the sternum was closed. All rabbits were successfully weaned from cardiopulmonary bypass. Blood gas analysis was unremarkable in all cases. Foreign blood was not administered. Although statistical significance was not achieved, there was a reduced expression of inflammatory markers in the MiniHLM group. The newly developed MiniHLM prototype was tested successfully in a small animal model in terms of technical function and expression of inflammation. Upcoming tests with the industrially manufactured MiniHLM may reveal the advantages of the MiniHLM in comparison with the conventional HLM. PMID:21092034

Schnoering, Heike; Arens, Jutta; Terrada, Estella; Sachweh, Joerg S; Runge, Maximilian; Schmitz-Rode, Thomas; Steinseifer, Ulrich; Vazquez-Jimenez, Jaime F

2010-11-01

9

Penetrating nail-gun injury of the heart managed by adenosine-induced asystole in the absence of a heart-lung machine.  

PubMed

During his work, an 18-year-old carpenter-in-training overbalanced and shot himself in the left median thorax with a nail gun. The patient was delivered to our thoracic surgery unit with a tentative diagnosis of penetrating lung trauma. An emergent computed tomogram showed a heart-penetrating nail injury. The patient was taken to the operating room, where he underwent emergency surgery that included sternotomy, pericardiotomy, extraction of the nail, and trauma treatment of the heart injury. The surgery was performed in a unit without a heart-lung machine. For that reason, asystole was chemically induced by the intravenous administration of adenosine. The surgery was successful, and the patient was discharged from the hospital on the 10th postoperative day. In cases of penetrating injuries of the heart, especially those with a foreign body retained in situ, we believe that the intravenous administration of adenosine is an elegant solution for the rapid provocation of asystole. In contrast to other methods, adenosine-induced asystole enables relatively safe myocardial manipulation in the absence of a cardiac surgical unit and a heart-lung machine. PMID:25120400

Rupprecht, Holger; Ghidau, Marius

2014-08-01

10

Penetrating Nail-Gun Injury of the Heart Managed by Adenosine-Induced Asystole in the Absence of a Heart-Lung Machine  

PubMed Central

During his work, an 18-year-old carpenter-in-training overbalanced and shot himself in the left median thorax with a nail gun. The patient was delivered to our thoracic surgery unit with a tentative diagnosis of penetrating lung trauma. An emergent computed tomogram showed a heart-penetrating nail injury. The patient was taken to the operating room, where he underwent emergency surgery that included sternotomy, pericardiotomy, extraction of the nail, and trauma treatment of the heart injury. The surgery was performed in a unit without a heart-lung machine. For that reason, asystole was chemically induced by the intravenous administration of adenosine. The surgery was successful, and the patient was discharged from the hospital on the 10th postoperative day. In cases of penetrating injuries of the heart, especially those with a foreign body retained in situ, we believe that the intravenous administration of adenosine is an elegant solution for the rapid provocation of asystole. In contrast to other methods, adenosine-induced asystole enables relatively safe myocardial manipulation in the absence of a cardiac surgical unit and a heart-lung machine. PMID:25120400

Rupprecht, Holger

2014-01-01

11

Heart-lung transplantation  

PubMed Central

Heart-lung transplantation itself is not a particularly difficult operation technically. It is the setting in which this procedure is performed which is difficult. The three issues of importance in a successful outcome are appropriate harvest of the heart-lung bloc from the donor, careful explant of the heart and lungs of the recipient, and finally the implant of the heart-lung bloc into the recipient. None of this requires extraordinary technical skill, but does require careful coordination and planning as well as adhering to some fundamental principles. One of the major pitfalls encountered is bleeding related to the explant procedure. Another is graft failure related to harvest and/or the implant procedure. The third is injury to either the phrenic nerve(s) or the left recurrent laryngeal nerve related to the explant procedure. Heart-lung transplantation is a major investment in resources of all sorts including financial, personnel, as well as the organs themselves. It is absolutely imperative that this procedure be performed only by experienced surgeons in centers with established expertise. PMID:25132983

Richey, Samuel R.

2014-01-01

12

76 FR 30371 - National Heart, Lung, and Blood Institute; Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Meetings...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-05-25

13

National Heart, Lung, and Blood Institute  

E-print Network

disorder, such as insomnia, sleep apnea, rest- less legs syndrome, or narcolepsy. Learn More More information on healthy sleep and sleep disorders is available from the National Heart, Lung, and BloodNational Heart, Lung, and Blood Institute A T - A - G L A N C E : Healthy Sleep S leep is not just

Bandettini, Peter A.

14

National Heart, Lung, and Blood Institute  

E-print Network

National Heart, Lung, and Blood Institute A T - A - G L A N C E : Physical Activity and Your Heart, is that even modest amounts of physi- cal activity are good for your health, especially your heart health activity is the type of physical activity that benefits your heart the most. This type of activity moves

Bandettini, Peter A.

15

National Heart, Lung, and Blood Institute  

E-print Network

or death. Over time, CHD can weaken the heart muscle and lead to heart failure and arrhythmias. Heart failure is a condition in which your heart can't pump enough blood throughout your body. ArrhythmiasNational Heart, Lung, and Blood Institute A T - A - G L A N C E : Coronary Heart Disease C oronary

Bandettini, Peter A.

16

National Heart, Lung, and Blood Institute  

E-print Network

problems, including heart attack, stroke, or even death. Overview Atherosclerosis can affect any artery-rich blood to your heart. CHD can lead to angina (chest pain) and heart attack. CHD is the leading causeNational Heart, Lung, and Blood Institute A T - A - G L A N C E : Atherosclerosis A therosclerosis

Bandettini, Peter A.

17

National Heart, Lung, and Blood Institute  

NSDL National Science Digital Library

The National Heart, Lung, and Blood Institute has crafted this excellent collection of materials for health care professionals. The materials are divided into a dozen sections, including Lung Information, Sleep Information, Interactive Tools and Resources, and Continuing Education Opportunities. The Interactive Tools and Resources area is a gem, as it includes applications for mobile devices such as a menu planner, a Body Mass Index (BMI) calculator, and an asthma mortality map. The Clinical Practice Guidelines area features reports crafted at professional development conferences that deal with cholesterol, obesity, and asthma. Additionally, the Continuing Education Opportunities area features guides to cultural competency and information about upcoming conferences and seminars.

18

77 FR 65568 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of Closed...Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2012-10-29

19

75 FR 71450 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of Closed...Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2010-11-23

20

77 FR 1703 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of Closed...Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2012-01-11

21

75 FR 52957 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of Closed...Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2010-08-30

22

77 FR 69639 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of Closed...Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2012-11-20

23

75 FR 33626 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of Closed...Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2010-06-14

24

77 FR 38849 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...Institutes of Health National Heart, Lung, and Blood Institute...Name of Committee: National Heart, Lung, and Blood Institute...Outcomes in Acute Respiratory Failure (R24). Date: July 18, 2012...Scientific Review/DERA, National Heart, Lung, and Blood...

2012-06-29

25

76 FR 1186 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...Name of Committee: National Heart, Lung, and Blood Institute...Name of Committee: National Heart, Lung, and Blood Institute...Research Project In Organ Failure. Date: January 26, 2011...Scientific Review/DERA, National Heart, Lung, and Blood...

2011-01-07

26

77 FR 18252 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2012-03-27

27

77 FR 44640 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2012-07-30

28

77 FR 64814 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2012-10-23

29

78 FR 33852 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2013-06-05

30

77 FR 31863 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2012-05-30

31

78 FR 18995 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2013-03-28

32

77 FR 43098 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2012-07-23

33

77 FR 76056 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2012-12-26

34

75 FR 8085 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2010-02-23

35

76 FR 55077 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-09-06

36

76 FR 78285 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Review Branch, DERA, National Heart, Lung, and Blood Institute, 6701...

2011-12-16

37

76 FR 27068 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-05-10

38

77 FR 9670 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2012-02-17

39

77 FR 2738 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2012-01-19

40

76 FR 29772 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-05-23

41

75 FR 31796 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2010-06-04

42

76 FR 12362 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-03-07

43

76 FR 11253 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-03-01

44

77 FR 3479 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2012-01-24

45

77 FR 64818 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2012-10-23

46

76 FR 58025 - National Heart, Lung and Blood Institute Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung and Blood Institute Notice of Closed...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-09-19

47

78 FR 37233 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2013-06-20

48

75 FR 80831 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2010-12-23

49

78 FR 67370 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...SERVICES National Institutes of Health National Heart, Lung, and Blood Institute; Notice of Closed...invasion of personal privacy. Name of Committee: Heart, Lung, and Blood Initial Review Group; Heart, Lung, and Blood Program Project Review...

2013-11-12

50

75 FR 9907 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2010-03-04

51

76 FR 3641 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-01-20

52

78 FR 30319 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2013-05-22

53

78 FR 33428 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...personal privacy. Name of Committee: Heart, Lung, and Blood Initial Review Group...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2013-06-04

54

78 FR 7792 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2013-02-04

55

76 FR 37132 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute, Special...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-06-24

56

75 FR 61507 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch, DERA, National Heart, Lung, and Blood Institute, 6701...

2010-10-05

57

75 FR 42756 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2010-07-22

58

75 FR 50771 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2010-08-17

59

77 FR 33473 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2012-06-06

60

77 FR 59935 - National Heart, Lung, And Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, And Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2012-10-01

61

76 FR 57062 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-09-15

62

77 FR 76058 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2012-12-26

63

75 FR 28032 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2010-05-19

64

77 FR 10538 - National Heart, Lung, and Blood Institute Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2012-02-22

65

77 FR 6571 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2012-02-08

66

76 FR 70154 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-11-10

67

76 FR 8752 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-02-15

68

78 FR 29375 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2013-05-20

69

77 FR 16843 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2012-03-22

70

75 FR 16152 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2010-03-31

71

76 FR 14674 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-03-17

72

78 FR 69431 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Office of Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2013-11-19

73

75 FR 36427 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2010-06-25

74

76 FR 12744 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-03-08

75

76 FR 37134 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-06-24

76

78 FR 12766 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National, Heart, Lung, and Blood Institute, 6701...

2013-02-25

77

75 FR 4092 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2010-01-26

78

78 FR 6122 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2013-01-29

79

76 FR 16631 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-03-24

80

76 FR 47218 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-08-04

81

75 FR 28260 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2010-05-20

82

78 FR 35637 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2013-06-13

83

78 FR 63483 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2013-10-24

84

76 FR 63625 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-10-13

85

75 FR 5090 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2010-02-01

86

76 FR 68200 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-11-03

87

76 FR 12123 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2011-03-04

88

77 FR 60705 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2012-10-04

89

78 FR 69431 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701...

2013-11-19

90

65 FR 78177 - National Heart, Lung, and Blood Institute, Submission for OMB Review; Comment Request; The...  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute, Submission...Paperwork Reduction Act of 1995, the National Heart, Lung, and Blood Institute (NHLBI...Epidemiology and Clinical Applications, National Heart, Lung, and Blood Institute. [FR...

2000-12-14

91

62 FR 14157 - National Heart, Lung, and Blood Institute; Submission for OMB Review; Comment Request; The...  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Submission...Paperwork Reduction Act of 1995, the National Heart, Lung, and Blood Institute (NHLBI...Project Clearance Liaison, National Heart, Lung, and Blood Institute, NIH,...

1997-03-25

92

70 FR 3715 - National Heart, Lung, and Blood Institute (NHLBI); Opportunity for a Cooperative Research and...  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute (NHLBI...SUMMARY: The National Heart, Lung, and Blood Institute (NHLBI...Technology Transfer Specialist, National Heart, Lung, and Blood Institute...

2005-01-26

93

61 FR 43556 - National Heart, Lung, and Blood Institute; Proposed Collection; Comment Request the Framingham Study  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Proposed...data collection projects, the National Heart, Lung, and Blood Institute (NHLBI...Project Clearance Liaison, National Heart, Lung, and Blood Institute, NIH,...

1996-08-23

94

69 FR 32031 - National Heart, Lung, and Blood Institute (NHLBI); Opportunity for a Cooperative Research and...  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute (NHLBI...Medicine Branch (P-CCMB) in National Heart, Lung, and Blood Institute (NHLBI...Technology Transfer Specialist, National Heart, Lung, and Blood Institute...

2004-06-08

95

61 FR 67842 - National Heart, Lung, and Blood Institute (NHLBI); Request for Capability Statements From Parties...  

Federal Register 2010, 2011, 2012, 2013, 2014

...DEPARTMENT OF HEALTH AND HUMAN SERVICES National Heart, Lung, and Blood Institute (NHLBI...SUMMARY: The National Heart, Lung, and Blood Institute (NHLBI...Technology Development Coordinator, National Heart, Lung, and Blood Institute,...

1996-12-24

96

65 FR 25338 - National Heart, Lung, and Blood Institute; Submission for OMB Review; Comment Request: The...  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Submission...Paperwork Reduction Act of 1995, the National Heart, Lung, and Blood Institute (NHLBI...Epidemiology and Clinical Applications, National Heart, Lung, and Blood Institute. [FR...

2000-05-01

97

65 FR 50999 - National Heart, Lung, and Blood Institute; Proposed Collection; Comment Request; The...  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Proposed...data collection projects, the National Heart, Lung, and Blood Institute (NHLBI...Epidemiology and Clinical Applications, National Heart, Lung, and Blood Institute. [FR...

2000-08-22

98

61 FR 5564 - National Heart, Lung, and Blood Institute; Opportunity for a Cooperative Research and Development...  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Opportunity...SUMMARY: The National Heart, Lung, and Blood Institute (NHLBI...system. This project is with the National Heart, Lung, and Blood Institute,...

1996-02-13

99

68 FR 48393 - National Heart, Lung, and Blood Institute: Licensing Opportunity and Cooperative Research and...  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute: Licensing...Named ``SPOC'' Cells AGENCY: National Heart, Lung, and Blood Institute. ACTION...SUMMARY: The National Heart Lung and Blood Institute is seeking...

2003-08-13

100

59 FR- National Heart, Lung and Blood Institute; Opportunity for a Cooperative Research and Development...  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung and Blood Institute; Opportunity...SUMMARY: The National Heart, Lung and Blood Institute (NHLBI) of...National Institutes of Health, National Heart, Lung and Blood Institute, 9000...

1994-05-17

101

66 FR 31679 - National Heart, Lung, and Blood Institute; Proposed Collection; Comment Request The Framingham Study  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Proposed...Paperwork Reduction Act of 1995, the National Heart, Lung, and Blood Institute (NHLBI...Epidemiology and Clinical Applications, National Heart, Lung and Blood Institute, 6701...

2001-06-12

102

69 FR 1590 - National Heart, Lung, and Blood Institute (NHLBI): Opportunity for Cooperative Research and...  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute (NHLBI...SUMMARY: The National Heart, Lung and Blood Institute (NHLBI) of...Technology Transfer and Development, National Heart, Lung, and Blood Institute,...

2004-01-09

103

69 FR 9830 - National Heart, Lung, and Blood Institute (NHLBI); Opportunity for a Cooperative Research and...  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute (NHLBI...Medicine Branch (P-CCMB) in National Heart, Lung, and Blood Institute (NHLBI...Technology Transfer Specialist, National Heart, Lung, and Blood Institute...

2004-03-02

104

68 FR 68088 - National Heart, Lung, and Blood Institute (NHLBI): Opportunity for Cooperative Research and...  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute (NHLBI...SUMMARY: The National Heart, Lung, and Blood Institute (NHLBI...Technology Transfer and Development, National Heart, Lung, and Blood Institute,...

2003-12-05

105

66 FR 20820 - National Heart, Lung, and Blood Institute; Proposed Collection; Comment Request; Multi-Ethnic...  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Proposed...data collection projects, the National Heart, Lung, and Blood Institute (NHLBI...Epidemiology and Clinical Applications, National Heart, Lung, and Blood Institute. [FR...

2001-04-25

106

77 FR 57099 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Heart, Lung, and Blood Institute; Notice of Closed...National Heart, Lung, and Blood Institute Special Emphasis Panel...Project for Gene Targeted Rat Models. Date: October 10, 2012...National Heart, Lung, and Blood Institute, 6701 Rockledge...

2012-09-17

107

78 FR 66754 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Heart, Lung, and Blood Institute; Notice of Closed...National Heart, Lung, and Blood Institute Special Emphasis Panel, Cardiovascular Disease Model Resource Related Research Project...National, Heart, Lung, and Blood Institute, 6701...

2013-11-06

108

78 FR 16860 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Heart, Lung, and Blood Institute; Notice of Closed...National Heart, Lung, and Blood Institute Special Emphasis Panel; Side Effects of Transfusion and Cellular Therapies...National Heart, Lung, and Blood Institute, 6701...

2013-03-19

109

76 FR 50742 - National Heart, Lung, and Blood Institute Notice of Closed Meeting  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Heart, Lung, and Blood Institute Notice of Closed...National Heart, Lung, and Blood Institute Special Emphasis...Pediatric Respiratory, Sleep, and Transfusion Medicine. Date: September...National Heart, Lung, and Blood Institute, 6701...

2011-08-16

110

73 FR 64340 - Memorandum of Understanding With the National Heart, Lung, and Blood Institute, a Part of the...  

Federal Register 2010, 2011, 2012, 2013, 2014

...Memorandum of Understanding With the National Heart, Lung, and Blood Institute, a Part of...and Research (CBER) and the National Heart, Lung, and Blood Institute (NHLBI...Blood Diseases and Resources, National Heart, Lung, and Blood Institute MSC...

2008-10-29

111

75 FR 51828 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting  

Federal Register 2010, 2011, 2012, 2013, 2014

...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel; Heart Failure Clinical Trial. Date: September 3, 2010...Officer, Review Branch/DERA, National Heart, Lung, and Blood Institute, 6701...

2010-08-23

112

75 FR 70273 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis...Antihypertensive and Lipid-Lowering to Prevent Heart Attack Trial. Date: December 1,...

2010-11-17

113

77 FR 71429 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel Jackson Heart Study Renewal. Date: December 17,...

2012-11-30

114

76 FR 25701 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...SERVICES National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...personal privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel, Heart Pumps for Clinical Trials for...

2011-05-05

115

77 FR 43343 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Notice of...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel; Jackson Heart Study RFA Review. Date: August 15,...

2012-07-24

116

68 FR 14669 - National Heart, Lung, and Blood Institute; Submission for OMB Review; Comment Request, Women's...  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Submission...the Office of the Director, the National Heart, Lung, and Blood Institute (NHLBI...postmenopausal women, namely, coronary heart disease, breast and colorectal...

2003-03-26

117

67 FR 59294 - National Heart, Lung, and Blood Institute; Proposed Collection; Comment Request; Women's Health...  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Proposed...Office of the Director, the National Heart, Lung, and Blood Institute (NHLBI...postmenopausal women, namely, coronary heart disease, breast and colorectal...

2002-09-20

118

63 FR 42864 - National Heart, Lung, and Blood Institute Proposed Collection; Comment Request Jackson Heart...  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute Proposed Collection; Comment Request Jackson Heart Study Participant Recruitment Survey...data collection projects, the National Heart, Lung, and Blood Institute...

1998-08-11

119

65 FR 69031 - National Heart, Lung, and Blood Institute; Proposed Collection; Comment Request, The Jackson...  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Proposed Collection; Comment Request, The Jackson Heart Study, Annual Follow-Up Component...data collection projects, the National Heart, Lung, and Blood Institute...

2000-11-15

120

65 FR 17513 - National Heart, Lung, and Blood Institute Submission for OMB Review; Comment Request Women's...  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute Submission...the Office of the Director, the National Heart, Lung, and Blood Institute (NHLBI...postmenopausal women, namely, coronary heart disease, breast and colorectal...

2000-04-03

121

64 FR 63325 - National Heart, Lung, and Blood Institute Proposed Collection; Comment Request The Jackson Heart...  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute Proposed Collection; Comment Request The Jackson Heart Study, Full Scale Exam I--Phase III...data collection projects, the National Heart, Lung, and Blood Institute...

1999-11-19

122

64 FR 48661 - National Heart, Lung, and Blood Institute; Proposed Collection; Comment Request; Women's Health...  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Proposed...Office of the Director, the National Heart, Lung, and Blood Institute (NHLBI...postmenopausal women, namely, coronary heart disease, breast and colorectal...

1999-09-07

123

71 FR 67148 - National Heart, Lung, and Blood Institute: Circulating Biomarkers of Cardiovascular Risk in the...  

Federal Register 2010, 2011, 2012, 2013, 2014

...SERVICES National Institutes of Health National Heart, Lung, and Blood Institute: Circulating Biomarkers of Cardiovascular Risk in the NHLBI's Framingham Heart Study AGENCY: National Heart, Lung, and Blood Institute, NIH, HHS....

2006-11-20

124

66 FR 14393 - National Heart, Lung and Blood Institute; Submission for OMB Review; Comment Request; The...  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung and Blood Institute; Submission...Paperwork Reduction Act of 1995, the National Heart, Lung, and Blood Institute (NHLBI...hypothetical risk factors and coronary heart disease [[Page 14394

2001-03-12

125

63 FR 14722 - National Heart, Lung, and Blood Institute; Submission for OMB Review; Comment Request, the...  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute; Submission...Paperwork Reduction Act of 1995, the National Heart, Lung, and Blood Institute, the National...hypothetical risk factors and coronary heart disease and stroke in people age 65...

1998-03-26

126

76 FR 19106 - National Heart, Lung, and Blood Institute; Notice of Meeting  

Federal Register 2010, 2011, 2012, 2013, 2014

...of Health National Heart, Lung, and Blood...of the Sickle Cell Disease Advisory Committee...Division of Blood Diseases and Resources, National Heart, Lung, and Blood...Research; 93.837, Heart and Vascular Diseases Research;...

2011-04-06

127

77 FR 14533 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...Committee: National Heart, Lung, and Blood Institute...Calcific Aortic Valve Disease. Date: April 4, 2012...Review/DERA, National Heart, Lung, and Blood Institute...Research; 93.837, Heart and Vascular Diseases Research;...

2012-03-12

128

77 FR 5261 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...Review/DERA, National Heart, Lung, and Blood Institute...Committee: National Heart, Lung, and Blood Institute...Haptoglobin for Sickle Cell Disease. Date: February 24...Research; 93.837, Heart and Vascular Diseases Research;...

2012-02-02

129

78 FR 57866 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...Committee: National Heart, Lung, and Blood...Myeloid Dysplasia Diseases. Date: October...Committee: National Heart, Lung, and Blood...Myeloid Dysplasia Diseases. Date: October...Research; 93.837, Heart and Vascular Diseases Research;...

2013-09-20

130

75 FR 66771 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...Committee: National Heart, Lung, and Blood Institute...Therapeutics in Lung Diseases (CADET I). Date...Branch/DERA, National Heart, Lung, and Blood Institute...Research; 93.837, Heart and Vascular Diseases Research;...

2010-10-29

131

78 FR 31952 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...Committee: National Heart, Lung, and Blood Institute...Research Projects in Blood Diseases. Date: June 18, 2013...Branch/DERA National Heart, Lung, and Blood Institute...Research; 93.837, Heart and Vascular Diseases Research;...

2013-05-28

132

76 FR 57061 - National Heart, Lung, and Blood Institute; Notice of Meeting  

Federal Register 2010, 2011, 2012, 2013, 2014

...of Health National Heart, Lung, and Blood...of the Sickle Cell Disease Advisory Committee...Division of Blood Diseases and Resources, National Heart, Lung, and Blood...Research; 93.837, Heart and Vascular Diseases Research;...

2011-09-15

133

75 FR 55807 - National Heart, Lung, and Blood Institute; Notice of Meeting  

Federal Register 2010, 2011, 2012, 2013, 2014

...of Health National Heart, Lung, and Blood...of the Sickle Cell Disease Advisory Committee...Division of Blood Diseases and Resources, National Heart, Lung, and Blood...Research; 93.837, Heart and Vascular Diseases Research;...

2010-09-14

134

77 FR 13134 - National Heart, Lung, and Blood Institute: Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...Committee: National Heart, Lung, and Blood Institute...Emphasis Panel; Sickle Cell Disease Program Project Grant...Review/DERA, National Heart, Lung, and Blood Institute...Research; 93.837, Heart and Vascular Diseases Research;...

2012-03-05

135

77 FR 66855 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...Committee: National Heart, Lung, and Blood Institute...Translational Programs in Lung Diseases. Date: November 27...Review/DERA, National Heart, Lung, and Blood Institute...Research; 93.837, Heart and Vascular Diseases Research;...

2012-11-07

136

75 FR 59276 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...Committee: National Heart, Lung, and Blood Institute...Translational Programs in Lung Diseases. Date: October 14-15...Branch/DERA, National Heart, Lung, and Blood Institute...Research; 93.837, Heart and Vascular Diseases Research;...

2010-09-27

137

76 FR 58285 - National Heart, Lung, and Blood Institute Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...Committee: National Heart, Lung, and Blood...in Cardiovascular Disease. Date: October...Committee: National Heart, Lung, and Blood...Trials for Lung Diseases (UM1). Date...Research; 93.837, Heart and Vascular Diseases Research;...

2011-09-20

138

78 FR 12767 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...Committee: National Heart, Lung, and Blood Institute...Translational Programs in Lung Diseases. Date: March 13, 2013...Review/DERA, National Heart, Lung, and Blood Institute...Research; 93.837, Heart and Vascular Diseases Research;...

2013-02-25

139

75 FR 66772 - National Heart, Lung, and Blood Institute; Notice of Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...Research, Division of Lung Diseases, National Heart, Lung, and Blood Institute...Research, Division of Lung Diseases, National Heart, Lung, and Blood Institute...Disorders Research; 93.837, Heart and Vascular Diseases Research; 93.838,...

2010-10-29

140

National Heart, Lung, and Blood Institute -- Information for Researchers  

NSDL National Science Digital Library

Hosted by the National Heart, Lung, and Blood Institute (NHLBI), this website provides a plethora of helpful information and resources for researchers. The site provides abstracts for NHLBI supported research from 1972-present, which also links to the NIH CRISP Database. Online research resources include Programs for Genomic Applications, Available Epidemiology and Clinical Trials Data Sets, as well as links to the NIH Obesity Research Web Site. The site also provides links to other research resources including databases, biologic resources, and training opportunities. In addition, the site links to the NHLBI Population Studies Database, information on the Framingham Heart Study, a section on Workshop and Meeting Summaries, and much more.

141

Renal complications following lung and heart-lung transplantation.  

PubMed

As survival improves after lung and heart-lung transplants, the long term detrimental impact of current management on renal function becomes more apparent as the number of non-renal solid organ transplant recipients on renal transplant waiting lists increases. Progressive chronic kidney disease (CKD) is a significant cause of morbidity and mortality in the transplant population. In this review we discuss the specific problems prior to lung or heart-lung transplant that predispose to CKD, as well as potential renal complications encountered during the peri- and post-transplant period. Significant acute and chronic nephrotoxicity is caused by calcineurin inhibitors (CNI). Mechanisms to decrease CNI exposure exist but have yet to be adopted in routine clinical care. Modifiable risk factors and the current screening and management approach taken at our institution are described. Pediatric nephrologists should be involved from an early stage. Future work will need to focus on identifying more accurate measures of renal function, given the limitations of current glomerular filtration rate estimation equations in a population where nutritional status may rapidly change post transplant. Multicentre studies of CNI minimisation strategies are required to guide future therapy that aims to minimise CKD development and progression in this vulnerable population. PMID:22733223

Robinson, Paul D; Shroff, Rukshana C; Spencer, Helen

2013-03-01

142

75 FR 19983 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...Heart, Lung, and Blood Institute Special Emphasis Panel, National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC). Date: May 12, 2010. Time: 10 a.m. to 1 p.m. Agenda: To review and...gov. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel, Functional Modeling of Pediatric Upper Airway Disorders.......

2010-04-16

143

59 FR- National Heart, Lung, and Blood Institute Grants for Prevention and Control Projects  

Federal Register 2010, 2011, 2012, 2013, 2014

...42 CFR Part 52e RIN 0905-AE25 National Heart, Lung, and Blood Institute Grants for...governing grants awarded by the National Heart, Lung, and Blood Institute (NHLBI...those segments of the public afflicted by heart, blood vessel, lung, and blood...

1994-11-17

144

68 FR 53177 - National Heart, Lung, and Blood Institute Proposed Collection; Comment Request Exam 2-The Jackson...  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute Proposed Collection...Comment Request Exam 2--The Jackson Heart Study, Annual Follow-Up Component SUMMARY...data collection projects, the National Heart, Lung, and Blood Institute...

2003-09-09

145

69 FR 5553 - National Heart, Lung, and Blood Institute Proposed Collection; Comment Request Exam 2-The Jackson...  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Institutes of Health National Heart, Lung, and Blood Institute Proposed Collection...Comment Request Exam 2--The Jackson Heart Study, Annual Follow-Up Component Summary...Paperwork Reduction Act of 1995, the National Heart, Lung, and Blood Institute...

2004-02-05

146

National Heart Lung and Blood Institute: Information for Health Professionals  

NSDL National Science Digital Library

Health care professionals and educators will be delighted to learn about this site, provided that they haven't heard about it already. Created by the National Heart Lung and Blood Institute, this site brings together a number of interactive tools and online resources that will be of great use to those in these fields. The site includes such materials as asthma mortality maps of the United States, BMI calculators, and a variety of other health assessment tools, such as menu planners and a ten-year heart attack risk calculator. Additionally, the site contains slide shows and downloadable slide sets on asthma, cholesterol, and high blood pressure that can be used by health care educators.

147

77 FR 50517 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting  

Federal Register 2010, 2011, 2012, 2013, 2014

...Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel; Maximizing Scientific Return on the Women's Health Initiative Biological Resource. Date: September 7, 2012. Time: 8:30 a.m. to 5:00 p.m. Agenda: To...

2012-08-21

148

78 FR 42967 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting  

Federal Register 2010, 2011, 2012, 2013, 2014

...of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel; Pediatric Pulmonary Vascular Disease Bioinformatics Clinical Coordinating Center. Date: August 29, 2013. Time: 9:30 a.m. to 12:00 p.m. Agenda: To review...

2013-07-18

149

77 FR 28612 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...of personal privacy. Name of Committee National Heart, Lung, and Blood Institute Special Emphasis Panel; Early Cystic Fibrosis in Humans. Date: June 5, 2012. Time: 8:00 AM to 5:00 PM. Agenda: To review and evaluate grant...

2012-05-15

150

77 FR 16844 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting  

Federal Register 2010, 2011, 2012, 2013, 2014

...Name of Committee: National Heart, Lung, and Blood Institute...Resource-related Application in Congenital Heart Diseases (R24). Date: April 17...Disorders Research; 93.837, Heart and Vascular Diseases Research; 93.838, Lung...

2012-03-22

151

The Role of School Health Education in Preventing Heart, Lung, and Blood Diseases.  

ERIC Educational Resources Information Center

This article reviews the scope and dynamics of heart, lung, and blood diseases and explains the need for research on primary prevention programs for children. Suggestions for school health education programs that contribute to disease prevention are delineated. (Author/DF)

Kolbe, Lloyd J.; Newman, Ian M.

1984-01-01

152

78 FR 1864 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting  

Federal Register 2010, 2011, 2012, 2013, 2014

...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel Phase II Trials in Lung Disease. Date: February 1, 2013. Time: 8:00 a.m. to 5:00 p.m. Agenda: To review and evaluate grant...

2013-01-09

153

77 FR 37911 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting  

Federal Register 2010, 2011, 2012, 2013, 2014

...privacy. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel; Phase II Trials in Lung Disease. Date: July 12, 2012. Time: 8:30 a.m. to 5:00 p.m. Agenda: To review and evaluate grant...

2012-06-25

154

ABNORMAL FUNCTIONAL DEVELOPMENT OF THE HEART, LUNGS, AND KIDNEYS: APPROACHES TO FUNCTIONAL TERATOLOGY  

EPA Science Inventory

Presentations given at the Conference on Abnormal Functional Development of the Heart, Lungs, and Kidneys are documented in this publication. The meeting was sponsored by the U.S. Environmental Protection Agency and was held in Asheville, NC, May 11-13, 1983. In an attempt to car...

155

75 FR 21644 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...yoh@mail.nih.gov. Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel, Women's Health Initiative Field. Date: May 19, 2010. Time: 8 a.m. to 3 p.m. Agenda: To review and evaluate contract...

2010-04-26

156

76 FR 61720 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel, Genomic Research in AAT-Deficiency and Sarcoidosis--Genomics and Informatics Center. Date: October 27, 2011. Time: 9:30 a.m. to 1 p.m. Agenda: To review...

2011-10-05

157

76 FR 61722 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...Comittee: National Heart, Lung, and Blood Institute Special Emphasis Panel, Genomic Research in AAT-Deficiency and Sarcoidosis--Clinical Centers. Date: October 26-27, 2011. Time: 12:30 p.m. to 9 a.m. Agenda: To review and...

2011-10-05

158

78 FR 42529 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting  

Federal Register 2010, 2011, 2012, 2013, 2014

...Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel Resource related project on genetically modified mice. Date: August 14, 2013. Time: 11:00 a.m. to 1:30 p.m. Agenda: To review and evaluate...

2013-07-16

159

78 FR 7791 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel; Resource related research project on genetically modified rats. Date: February 28, 2013. Time: 9:00 a.m. to 11:00 a.m. Agenda: To review and evaluate...

2013-02-04

160

78 FR 27411 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings  

Federal Register 2010, 2011, 2012, 2013, 2014

...Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel; NHLBI Resource-Related Project for Stem Cells and Cardiomyopathy. Date: June 6, 2013. Time: 1:00 p.m. to 3:00 p.m. Agenda: To review and evaluate...

2013-05-10

161

78 FR 10185 - National Heart, Lung, and Blood Institute; Notice of Closed Meeting  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Heart, Lung, and Blood Institute Special Emphasis Panel; SBIR Topic 72: New Methods to Detect and Assess Myocardial Fibrosis. Date: March 6, 2013. Time: 12:30 p.m. to 4:30 p.m. Agenda: To review and evaluate contract proposals....

2013-02-13

162

Changes in endocrine control of electrolyte homeostasis and blood pressure following heart and heart-lung transplantation. A comparative study.  

PubMed

The purpose of this study was to compare the early postoperative effects of heart and heart-lung transplantation on the secretion of atrial natriuretic peptide (alpha-ANP), renin, aldosterone, and vasopressin. This was carried out from the first to the eighth postoperative day in ten heart and five heart-lung recipients. The changes in the release of these hormones were similar in both groups. Vasopressin release remained stable while that of the renin-angiotensin-aldosterone system progressively returned to more normal levels. Grafted heart tissue was capable of high alpha-ANP release early on in both heart and in heart-lung recipients. This sustained alpha-ANP release was not a function of the resulting overall atrial tissue mass. Our findings suggest that it might be the consequence of an intrinsic hypersecretion of alpha-ANP resulting from the loss of normal heart innervation occurring in both heart and heart-lung transplantation. PMID:1532548

Mertes, P M; de Talancé, N; Pinelli, G; Villemot, J P; Burlet, C; Boulangé, M

1992-04-01

163

76 FR 49775 - Food and Drug Administration/National Heart, Lung, and Blood Institute/National Science...  

Federal Register 2010, 2011, 2012, 2013, 2014

...Heart, Lung, and Blood Institute/National Science Foundation Public Workshop on Computer Methods for Medical Devices AGENCY: Food and...National Institutes of Health and the National Science Foundation (NSF). The purpose of the...

2011-08-11

164

75 FR 18849 - Food and Drug Administration/National Heart Lung and Blood Institute/National Science Foundation...  

Federal Register 2010, 2011, 2012, 2013, 2014

...National Heart Lung and Blood Institute/National Science Foundation Workshop on Computer Methods for Cardiovascular Devices: The Integration...National Institutes of Health and the National Science Foundation. The purpose of the workshop is...

2010-04-13

165

Dr. Sonia Skarlatos and the National Heart, Lung, and Blood Institute Translational Research and Resource Programs  

PubMed Central

Abstract Sonia I. Skarlatos, PhD (September 28, 1953–August 6, 2013), was the deputy director of the Division of Cardiovascular Sciences at the National Heart, Lung, and Blood Institute (NHLBI). This article reviews her work in establishing, leading, or facilitating extramural translational research programs supported by the NHLBI, specifically focusing on her work as a consistent advocate for the advancement of gene and cell therapies. PMID:24164237

2013-01-01

166

A novel approach in extracorporeal circulation: individual, integrated, and interactive heart-lung assist (I3-Assist).  

PubMed

Extracorporeal life support (ECLS) is a well-established technique for the treatment of different cardiac and pulmonary diseases, e.g., congenital heart disease and acute respiratory distress syndrome. Additionally, severely ill patients who cannot be weaned from the heart-lung machine directly after surgery have to be put on ECLS for further therapy. Although both systems include identical components, a seamless transition is not possible yet. The adaption of the circuit to the patients' size and demand is limited owing to the components available. The project I³-Assist aims at a novel concept for extracorporeal circulation. To better match the patient's therapeutic demand of support, an individual number of one-size oxygenators and heat exchangers will be combined. A seamless transition between cardiopulmonary bypass and ECLS will be possible as well as the exchange of components during therapy to enhance circuit maintenance throughout long-term support. Until today, a novel oxygenator and heat exchanger along with a simplified manufacturing protocol have been established. The first layouts of the unit to allow the spill- and bubble-free connection and disconnection of modules as well as improved cannulas and a rotational pump are investigated using computational fluid dynamics. Tests were performed according to current guidelines in vitro and in vivo. The test results show the feasibility and potential of the concept. PMID:24327525

Wagner, Georg; Schlanstein, Peter; Fiehe, Sandra; Kaufmann, Tim; Kopp, Rüdger; Bensberg, Ralf; Schmitz-Rode, Thomas; Steinseifer, Ulrich; Arens, Jutta

2014-04-01

167

Leukocyte redistribution and eicosanoid changes during the autoperfused working heart-lung preparation.  

PubMed

We studied the role of leukocyte redistribution and eicosanoid changes in the early stages of instituting 16 rabbit autoperfused working heart-lung preparations (AWHLP). Physiological changes occurring during the transition from the intact animal to the AWHLP may determine the survival and viability of the organ blocks for transplantation. White blood cell (WBC) count decreased from 5,160/microL to 1430/microL (P less than .01) at 60 min of autoperfusion. Differential WBC counts performed in ten of these AWHLP revealed a 63% decrease in lymphocyte count and an 88% decrease in the granulocyte count at 60 min. Thus, the predominant leukocyte remaining in the circulation was the lymphocyte. Blood samples were collected from the intact animal and from the AWHLP for assay of the stable metabolites of thromboxane A2 (TxA2) and prostacyclin (PGI2). Transition from the in situ heart-lung block to the in vitro AWHLP stage caused significant changes in these metabolites. The PGI2 metabolite 6-ketoprostaglandin F1a (6KPGF1a) increased from 2680 +/- 487 to 4339 +/- 478 (pg/mL), P less than .05, while the TxA2 metabolite, thromboxane B2 (TxB2) decreased from 618 +/- 105 to 289 +/- 63 (pg/mL). However, assays of 11-dehydro-TxB2 (11-DHT), a longer lived metabolite of TxA2 (n = 7) increased (668.4 +/- 84.6 to 946.4 +/- 43.7, P less than .05). The transition from the in situ heart-lung block of the intact animal to the AWHLP involves significant physiological changes. Redistribution of leukocytes occurs with a predominant decrease in the granulocyte count, while levels of bioactive lipid mediators show a distinct large rise in the PGI2 metabolites and a lesser increase in TxA2 metabolites.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:1777442

Genco, C M; Bernstein, E A; Connolly, R J; Peterson, M B; Zhang, X; Somerville, K; Cleveland, R J; Diehl, J T

1991-01-01

168

Super liquid-repellent gas membranes for carbon dioxide capture and heart–lung machines  

PubMed Central

In a gas membrane, gas is transferred between a liquid and a gas through a microporous membrane. The main challenge is to achieve a high gas transfer while preventing wetting and clogging. With respect to the oxygenation of blood, haemocompatibility is also required. Here we coat macroporous meshes with a superamphiphobic—or liquid repellent—layer to meet this challenge. The superamphiphobic layer consists of a fractal-like network of fluorinated silicon oxide nanospheres; gas trapped between the nanospheres keeps the liquid from contacting the wall of the membrane. We demonstrate the capabilities of the membrane by capturing carbon dioxide gas into a basic aqueous solution and in addition use it to oxygenate blood. Usually, blood tends to clog membranes because of the abundance of blood cells, platelets, proteins and lipids. We show that human blood stored in a superamphiphobic well for 24?h can be poured off without leaving cells or adsorbed protein behind. PMID:24065073

Paven, Maxime; Papadopoulos, Periklis; Schöttler, Susanne; Deng, Xu; Mailänder, Volker; Vollmer, Doris; Butt, Hans-Jürgen

2013-01-01

169

Elucidating Nature’s Solutions to Heart, Lung, and Blood Diseases and Sleep Disorders  

PubMed Central

Evolution has provided a number of animal species with extraordinary phenotypes. Several of these phenotypes allow species to survive and thrive in environmental conditions that mimic disease states in humans. The study of evolved mechanisms that responsible for these phenotypes may provide insights into the basis of human disease and guide the design of new therapeutic approaches. Examples include species that tolerate acute or chronic hypoxemia like deep-diving mammals and high-altitude inhabitants, as well as those that hibernate and interrupt their development when exposed to adverse environments. The evolved traits exhibited by these animal species involve modifications of common biological pathways that affect metabolic regulation, organ function, antioxidant defenses, and oxygen transport. In 2006, the National Heart, Lung, and Blood Institute (NHLBI) released a funding opportunity announcement to support studies that were designed to elucidate the natural molecular and cellular mechanisms of adaptation in species that tolerate extreme environmental conditions. The rationale for this funding opportunity is detailed in this Special Article, and the specific evolved mechanisms examined in the supported research are described. Also highlighted are past medical advances achieved through the study of animal species that have evolved extraordinary phenotypes as well as the expectations for new understanding of nature’s solutions to heart, lung, blood, and sleep disorders through future research in this area. PMID:22461362

Carey, Hannah V.; Martin, Sandra L.; Horwitz, Barbara A.; Yan, Lin; Bailey, Shannon M.; Podrabsky, Jason; Storz, Jay F.; Ortiz, Rudy M.; Wong, Renee P.; Lathrop, David A.

2012-01-01

170

National Heart, Lung, and Blood Institute and the translation of cardiovascular discoveries into therapeutic approaches.  

PubMed

The molecular causes of ?4000 medical conditions have been described, yet only 5% have associated therapies. For decades, the average time for drug development through approval has taken 10 to 20 years. In recent years, the serious challenges that confront the private sector have made it difficult to capitalize on new opportunities presented by advances in genomics and cellular therapies. Current trends are disturbing. Pharmaceutical companies are reducing their investments in research, and biotechnology companies are struggling to obtain venture funds. To support early-stage translation of the discoveries in basic science, the National Institutes of Health and the National Heart, Lung, and Blood Institute have developed new approaches to facilitating the translation of basic discoveries into clinical applications and will continue to develop a variety of programs that create teams of academic investigators and industry partners. The goal of these programs is to maximize the public benefit of investment of taxpayer dollars in biomedical research and to lessen the risk required for industry partners to make substantial investments. This article highlights several examples of National Heart, Lung, and Blood Institute-initiated translational programs and National Institutes of Health translational resources designed to catalyze and enable the earliest stages of the biomedical product development process. The translation of latest discoveries into therapeutic approaches depends on continued federal funding to enhance the early stages of the product development process and to stimulate and catalyze partnerships between academia, industry, and other sources of capital. PMID:23620235

Galis, Zorina S; Black, Jodi B; Skarlatos, Sonia I

2013-04-26

171

[Transplantation of the heart-lung complex (the first clinical experience)].  

PubMed

The article deals with experience in the first transplantation of a heart-lung complex in the USSR. The recipient was a 34-year-old male with dilation cardiomyopathy. It was decided to perform the transplantation because the terminal stage of cardiac failure and secondary pulmonary hypertension developed (cardiac index 1.3 l/m, pressure in pulmonary artery 80/50 mm Hg, resistance of pulmonary vessels 10.4 units after Wood). The heart and lung were transplanted from a 19-year-old male who died from a craniocerebral injury. Cyclosporine, metipred , imuran, dopamine in small doses, cardiotonics, and antibiotics were given in the postoperative period; the patient was kept on artificial respiration for 48 hours. For up to 10 days the patient's condition was relatively stable and his consciousness was clear. Bilateral pneumonia developed, however, from which he died on the 12th postoperative day. The article discusses organizational problems and some questions of immunosuppressive therapy, immunological monitoring, and the management of patients after transplantation of a heart-lung complex. PMID:1770747

Akchurin, R S; Mukharliamov, N M; Lepilin, M G; Brand, Ia B; Shiriaev, A A; Partigulov, S A; Vasil'ev, A V; Agapov, A A; Masenko, V P; Zhdanov, V S

1991-06-01

172

The Relationship between National Heart, Lung, and Blood Institute Weight Guidelines and Concurrent Medical Costs in a Manufacturing Population.  

ERIC Educational Resources Information Center

Explored the relationship between the 1998 National Heart, Lung, and Blood Institute (NHLBI) weight guidelines and concurrent medical costs among 177,971 employees, retirees, and adult dependents from a nationwide manufacturing corporation. Results indicated that the six weight groups defined by the NHLBI guidelines were consistent with concurrent…

Wang, Feifei; Schultz, Alyssa B.; Musich, Shirley; McDonald, Tim; Hirschland, David; Edington, Dee W.

2003-01-01

173

Increasing the Number of Competing Awards at the National Heart, Lung, and Blood Institute: Projections of a Model.  

ERIC Educational Resources Information Center

The National Heart, Lung, and Blood Institute (NHLBI) has begun funding longer research award terms, limiting the number of projects to be funded. A model was developed to assess alternative research funding policies that might allow NHLBI to support more competing awards. Findings and implications for research stability are reported. (Author/MSE)

Roth, Carl A.; Lenfant, Claude

1991-01-01

174

Heart—lung and lung transplantation in grown-up congenital heart disease: long-term single centre experience  

Microsoft Academic Search

Objective: Because of considerable progress in paediatric cardiac surgery life expectancy of patients with congenital heart disease (CHD) has improved significantly over the years. There are a growing number of adults with CHD presenting with progressive decline of cardiopulmonary function and Eisenmenger's syndrome. We analysed our experience with heart—lung and lung transplantation in this patient group. Methods: Since 1988, a

Heidi Goerler; Andre Simon; Bernhard Gohrbandt; Christian Hagl; Petra Oppelt; Juergen Weidemann; Axel Haverich; Martin Strueber

175

Heart–lung and lung transplantation in grown-up congenital heart disease: long-term single centre experience  

Microsoft Academic Search

Objective: Because of considerable progress in paediatric cardiac surgery life expectancy of patients with congenital heart disease (CHD) has improved significantly over the years. There are a growing number of adults with CHD presenting with progressive decline of cardiopulmonary function and Eisenmenger's syndrome. We analysed our experience with heart–lung and lung transplantation in this patient group. Methods: Since 1988, a

Heidi Goerler; Andre Simon; Bernhard Gohrbandt; Christian Hagl; Petra Oppelt; Juergen Weidemann; Axel Haverich; Martin Strueber

2007-01-01

176

Assessment and treatment of depression in patients with cardiovascular disease: National heart, lung, and blood institute working group report  

Microsoft Academic Search

Objective: The National Heart, Lung, and Blood Institute convened an interdisciplinary working group of experts to develop recommendations for the assessment and treatment of depression in patients with coronary heart disease (CHD). Method: Consensus of experts. Results: Our current recommendations are that the Beck Depression Inventory-I be employed for epidemiological studies of depression and CHD, that the Patient Health Questionnaire

Karina W. Davidson; David J. Kupfer; J. Thomas Bigger; Robert M. Califf; Robert M. Carney; James C. Coyne; Susan M. Czajkowski; Ellen Frank; Nancy Frasure-Smith; Kenneth E. Freedland; Erika S. Froelicher; Alexander H. Glassman; Wayne J. Katon; Peter G. Kaufmann; Ronald C. Kessler; Helena C. Kraemer; K. Ranga R. Krishnan; François Lespérance; Nina Rieckmann; David S. Sheps; Jerry M. Suls

2006-01-01

177

Conformal piezoelectric energy harvesting and storage from motions of the heart, lung, and diaphragm  

PubMed Central

Here, we report advanced materials and devices that enable high-efficiency mechanical-to-electrical energy conversion from the natural contractile and relaxation motions of the heart, lung, and diaphragm, demonstrated in several different animal models, each of which has organs with sizes that approach human scales. A cointegrated collection of such energy-harvesting elements with rectifiers and microbatteries provides an entire flexible system, capable of viable integration with the beating heart via medical sutures and operation with efficiencies of ?2%. Additional experiments, computational models, and results in multilayer configurations capture the key behaviors, illuminate essential design aspects, and offer sufficient power outputs for operation of pacemakers, with or without battery assist. PMID:24449853

Dagdeviren, Canan; Yang, Byung Duk; Su, Yewang; Tran, Phat L.; Joe, Pauline; Anderson, Eric; Xia, Jing; Doraiswamy, Vijay; Dehdashti, Behrooz; Feng, Xue; Lu, Bingwei; Poston, Robert; Khalpey, Zain; Ghaffari, Roozbeh; Huang, Yonggang; Slepian, Marvin J.; Rogers, John A.

2014-01-01

178

Optogenetic sensors and effectors: CHROMus—the Cornell Heart Lung Blood Institute Resource for Optogenetic Mouse Signaling  

PubMed Central

Significant progress has been made in the last decade in the development of optogenetic effectors and sensors that can be deployed to understand complex biological signaling in mammals at a molecular level, without disrupting the distributed, lineage specific signaling circuits that comprise nuanced physiological responses. A major barrier to the widespread exploitation of these imaging tools, however, is the lack of readily available genetic reagents that can be easily combined to probe complex biological processes. Ideally, one could envision purpose–produced mouse lines expressing optically compatible sensors and effectors, sensor pairs in distinct lineages, or sensor pairs in discrete subcellular compartments, such that they could be crossed to enable in vivo imaging studies of unprecedented scientific power. Such lines could also be combined with mice to determine the alteration in signaling accompanying targeted gene deletion or addition. In order to address this lack, the National Heart Lung and Blood Institute has recently funded an optogenetic resource designed to create optically compatible, combinatorial mouse lines that will advance NHLBI research. Here we review recent advances in optogenetic sensor and effectors and describe the rationale and goals for the establishment of the Cornell/National Heart Lung Blood Resource for Optogenetic Mouse Signaling (CHROMus). PMID:25414670

Shui, Bo; Lee, Jane C.; Reining, Shaun; Lee, Frank K.; Kotlikoff, Michael I.

2014-01-01

179

This lesson plan is part of the National Heart, Lung, and Blood Institute's (NHLBI) heart attack education campaign, Act in Time to Heart Attack Signs.  

E-print Network

#12;#12;#12;This lesson plan is part of the National Heart, Lung, and Blood Institute's (NHLBI) heart attack education campaign, Act in Time to Heart Attack Signs. It was designed to be the 10th session of an existing 9-session heart health education course for Latinos entitled Your Heart, Your Life

Bandettini, Peter A.

180

Cardiovascular Epidemiology in a Changing World—Challenges to Investigators and the National Heart, Lung, and Blood Institute  

PubMed Central

Over the past 60 years, revolutionary discoveries made by epidemiologists have contributed to marked declines in cardiovascular disease morbidity and mortality. Now, in an era of increasingly constrained resources, researchers in cardiovascular epidemiology face a number of challenges that call for novel, paradigm-shifting approaches. In this paper, the authors pose to the community 4 critical questions: 1) How can we avoid wasting resources on studies that provide little incremental knowledge? 2) How can we assure that we direct our resources as economically as possible towards innovative science? 3) How can we be nimble, responding quickly to new opportunities? 4) How can we identify prospectively the most meritorious research questions? Senior program staff at the National Heart, Lung, and Blood Institute invite the epidemiology community to join them in an ongoing Web-based blog conversation so that together we might develop novel approaches that will facilitate the next generation of high-impact discoveries. PMID:22415032

Sorlie, Paul D.; Bild, Diane E.; Lauer, Michael S.

2012-01-01

181

Strategic transformation of population studies: recommendations of the working group on epidemiology and population sciences from the national heart, lung, and blood advisory council and board of external experts.  

PubMed

In 2013, the National Heart, Lung, and Blood Institute assembled a working group on epidemiology and population sciences from its Advisory Council and Board of External Experts. The working group was charged with making recommendations to the National Heart, Lung, and Blood Advisory Council about how the National Heart, Lung, and Blood Institute could take advantage of new scientific opportunities and delineate future directions for the epidemiology of heart, lung, blood, and sleep diseases. Seven actionable recommendations were proposed for consideration. The themes included 1) defining the compelling scientific questions and challenges in population sciences and epidemiology of heart, lung, blood, and sleep diseases; 2) developing methods and training mechanisms to integrate "big data" science into the practice of epidemiology; 3) creating a cohort consortium and inventory of major studies to optimize the efficient use of data and specimens; and 4) fostering a more open, competitive approach to evaluating large-scale longitudinal epidemiology and population studies. By building on the track record of success of the heart, lung, blood, and sleep cohorts to leverage new data science opportunities and encourage broad research and training partnerships, these recommendations lay a strong foundation for the transformation of heart, lung, blood, and sleep epidemiology. PMID:25743324

Roger, Véronique L; Boerwinkle, Eric; Crapo, James D; Douglas, Pamela S; Epstein, Jonathan A; Granger, Christopher B; Greenland, Philip; Kohane, Isaac; Psaty, Bruce M

2015-03-15

182

Complication Probability Models for Radiation-Induced Heart Valvular Dysfunction: Do Heart-Lung Interactions Play a Role?  

PubMed Central

Purpose The purpose of this study is to compare different normal tissue complication probability (NTCP) models for predicting heart valve dysfunction (RVD) following thoracic irradiation. Methods All patients from our institutional Hodgkin lymphoma survivors database with analyzable datasets were included (n?=?90). All patients were treated with three-dimensional conformal radiotherapy with a median total dose of 32 Gy. The cardiac toxicity profile was available for each patient. Heart and lung dose-volume histograms (DVHs) were extracted and both organs were considered for Lyman-Kutcher-Burman (LKB) and Relative Seriality (RS) NTCP model fitting using maximum likelihood estimation. Bootstrap refitting was used to test the robustness of the model fit. Model performance was estimated using the area under the receiver operating characteristic curve (AUC). Results Using only heart-DVHs, parameter estimates were, for the LKB model: D50?=?32.8 Gy, n?=?0.16 and m?=?0.67; and for the RS model: D50?=?32.4 Gy, s?=?0.99 and ??=?0.42. AUC values were 0.67 for LKB and 0.66 for RS, respectively. Similar performance was obtained for models using only lung-DVHs (LKB: D50?=?33.2 Gy, n?=?0.01, m?=?0.19, AUC?=?0.68; RS: D50?=?24.4 Gy, s?=?0.99, ??=?2.12, AUC?=?0.66). Bootstrap result showed that the parameter fits for lung-LKB were extremely robust. A combined heart-lung LKB model was also tested and showed a minor improvement (AUC?=?0.70). However, the best performance was obtained using the previously determined multivariate regression model including maximum heart dose with increasing risk for larger heart and smaller lung volumes (AUC?=?0.82). Conclusions The risk of radiation induced valvular disease cannot be modeled using NTCP models only based on heart dose-volume distribution. A predictive model with an improved performance can be obtained but requires the inclusion of heart and lung volume terms, indicating that heart-lung interactions are apparently important for this endpoint. PMID:25360627

Cella, Laura; Palma, Giuseppe; Deasy, Joseph O.; Oh, Jung Hun; Liuzzi, Raffaele; D’Avino, Vittoria; Conson, Manuel; Pugliese, Novella; Picardi, Marco; Salvatore, Marco; Pacelli, Roberto

2014-01-01

183

A computer simulation model of the cost-effectiveness of routine Staphylococcus aureus screening and decolonization among lung and heart-lung transplant recipients.  

PubMed

Our objective was to model the cost-effectiveness and economic value of routine peri-operative Staphylococcus aureus screening and decolonization of lung and heart-lung transplant recipients from hospital and third-party payer perspectives. We used clinical data from 596 lung and heart-lung transplant recipients to develop a model in TreeAge Pro 2009 (Williamsport, MA, USA). Sensitivity analyses varied S. aureus colonization rate (5-15 %), probability of infection if colonized (10-30 %), and decolonization efficacy (25-90 %). Data were collected from the Cardiothoracic Transplant Program at the University of Pittsburgh Medical Center. Consecutive lung and heart-lung transplant recipients from January 2006 to December 2010 were enrolled retrospectively. Baseline rates of S. aureus colonization, infection and decolonization efficacy were 9.6 %, 36.7 %, and 31.9 %, respectively. Screening and decolonization was economically dominant for all scenarios tested, providing more cost savings and health benefits than no screening. Savings per case averted (2012 $US) ranged from $73,567 to $133,157 (hospital perspective) and $10,748 to $16,723 (third party payer perspective), varying with the probability of colonization, infection, and decolonization efficacy. Using our clinical data, screening and decolonization led to cost savings per case averted of $240,602 (hospital perspective) and averted 6.7?S. aureus infections (4.3 MRSA and 2.4 MSSA); 89 patients needed to be screened to prevent one S. aureus infection. Our data support routine S. aureus screening and decolonization of lung and heart-lung transplant patients. The economic value of screening and decolonization was greater than in previous models of other surgical populations. PMID:24500598

Clancy, C J; Bartsch, S M; Nguyen, M H; Stuckey, D R; Shields, R K; Lee, B Y

2014-06-01

184

Childhood overweight and cardiovascular disease risk factors: The National Heart, Lung, and Blood Institute Growth and Health Study  

PubMed Central

Objective To estimate the prevalence and incidence of overweight in black and white girls, and to examine associations between adolescent overweight and cardiovascular disease (CVD) risk factors. Study design In the National Heart, Lung, and Blood Institute Growth and Health Study (NGHS), annual measurements were obtained from girls followed longitudinally between the ages of 9 or 10 and 18; self-reported measures were obtained at ages 21-23. Participants were 1,166 white and 1,213 black girls. Childhood overweight as defined by the Centers for Disease Control and Prevention (CDC) was the independent variable of primary interest. Measured outcomes included blood pressure and lipid levels. Results Rates of overweight increased through adolescence from 7% to 10% in white girls and 17% to 24% in black girls. Incidence of overweight was greater during ages 9-12 than in later adolescence. Girls who were overweight during childhood were 11 to 30 times more likely to be obese in young adulthood. Overweight was significantly associated with increased percent body fat, sum of skinfolds and waist circumference, unhealthful systolic and diastolic blood pressure, HDL cholesterol and triglycerides. Conclusion The relationship between CVD risk factors and CDC-defined overweight is present at age 9. PMID:17188606

Thompson, Douglas R.; Obarzanek, Eva; Franko, Debra L.; Barton, Bruce A.; Morrison, John; Biro, Frank M.; Daniels, Stephen R.; Striegel-Moore, Ruth H.

2007-01-01

185

Inherited arrhythmias: a National Heart, Lung, and Blood Institute and Office of Rare Diseases workshop consensus report about the diagnosis, phenotyping, molecular mechanisms, and therapeutic approaches for primary cardiomyopathies of gene mutations affe  

Microsoft Academic Search

The National Heart, Lung, and Blood Institute and Office of Rare Diseases at the National Institutes of Health organized a workshop (September 14 to 15, 2006, in Bethesda, Md) to advise on new research directions needed for improved identification and treatment of rare inherited arrhythmias. These included the following: (1) Na+ channelopathies; (2) arrhythmias due to K+ channel mutations; and

Stephan E Lehnart; Michael J Ackerman; D Woodrow Benson; Ramon Brugada; Colleen E Clancy; J Kevin Donahue; Alfred L George; Augustus O Grant; Stephen C Groft; Craig T January; David a Lathrop; W Jonathan Lederer; Jonathan C Makielski; Peter J Mohler; Arthur Moss; Jeanne M Nerbonne; Timothy M Olson; Dennis a Przywara; Jeffrey a Towbin; Lan-Hsiang Wang; Andrew R Marks

2007-01-01

186

Design progress of the ultracompact integrated heart lung assist device--part 1: effect of vaned diffusers on gas-transfer performances.  

PubMed

The integrated heart lung assist device (IHLAD) has been developed to overcome the problems of currently available extracorporeal membrane oxygenation devices. The integrated structure of a centrifugal blood pump and cylindrical bundle of polyolefin hollow-fibers has allowed a remarkably compact size for the device. This study deals with the design change of the IHLAD that added to the vaned diffuser between the impeller of the centrifugal pump and the hollow-fiber bundle with a view to enhancing the gas-transfer performance. Ex vivo gas-transfer performance tests were carried out, as well as hydrodynamic characteristics and hemolysis test using fresh goat blood. The oxygen transfer rate was generally improved, and the carbon dioxide removal rate was slightly improved. Intolerable amount of hemolysis (index of hemolysis= 0.177) was caused by the IHLAD, which must be resolved by improving the design in the future. PMID:14616534

Tsukiya, Tomonori; Tatsumi, Eisuke; Nishinaka, Tomohiro; Katagiri, Nobumasa; Takewa, Yoshiaki; Ohnishi, Hiroyuki; Oshikawa, Mitsuo; Shioya, Kyoko; Mizuno, Toshihide; Taenaka, Yoshiyuki; Takano, Hisateru; Kitamura, Soichiro

2003-10-01

187

Ethical and practical guidelines for reporting genetic research results to study participants: updated guidelines from a National Heart, Lung, and Blood Institute working group.  

PubMed

In January 2009, the National Heart, Lung, and Blood Institute convened a 28-member multidisciplinary Working Group to update the recommendations of a 2004 National Heart, Lung, and Blood Institute Working Group focused on Guidelines to the Return of Genetic Research Results. Changes in the genetic and societal landscape over the intervening 5 years raise multiple questions and challenges. The group noted the complex issues arising from the fact that technological and bioinformatic progress has made it possible to obtain considerable information on individuals that would not have been possible a decade ago. Although unable to reach consensus on a number of issues, the working group produced 5 recommendations. The working group offers 2 recommendations addressing the criteria necessary to determine when genetic results should and may be returned to study participants, respectively. In addition, it suggests that a time limit be established to limit the duration of obligation of investigators to return genetic research results. The group recommends the creation of a central body, or bodies, to provide guidance on when genetic research results are associated with sufficient risk and have established clinical utility to justify their return to study participants. The final recommendation urges investigators to engage the broader community when dealing with identifiable communities to advise them on the return of aggregate and individual research results. Creation of an entity charged to provide guidance to institutional review boards, investigators, research institutions, and research sponsors would provide rigorous review of available data, promote standardization of study policies regarding return of genetic research results, and enable investigators and study participants to clarify and share expectations for the handling of this increasingly valuable information with appropriate respect for the rights and needs of participants. PMID:21156933

Fabsitz, Richard R; McGuire, Amy; Sharp, Richard R; Puggal, Mona; Beskow, Laura M; Biesecker, Leslie G; Bookman, Ebony; Burke, Wylie; Burchard, Esteban Gonzalez; Church, George; Clayton, Ellen Wright; Eckfeldt, John H; Fernandez, Conrad V; Fisher, Rebecca; Fullerton, Stephanie M; Gabriel, Stacey; Gachupin, Francine; James, Cynthia; Jarvik, Gail P; Kittles, Rick; Leib, Jennifer R; O'Donnell, Christopher; O'Rourke, P Pearl; Rodriguez, Laura Lyman; Schully, Sheri D; Shuldiner, Alan R; Sze, Rebecca K F; Thakuria, Joseph V; Wolf, Susan M; Burke, Gregory L

2010-12-01

188

Inhibition by thiamine tetrahydrofurfuryl disulfide (TTFD) of the arachidonic acid cascade-line activation as evidenced in the heart-lung preparation of the dog.  

PubMed

The effects of thiamine tetrahydrofurfuryl disulfide (TTFD) on the gradual increase in the coronary blood flow (CBF) inherent in the canine heart-lung preparation were studied. TTFD is a disulfide-type derivative of thiamine reported to have an antiinflammatory effect in experimental animals. Since it was found that the substance could reverse the gradual increase in CBF, the possibility that the reversal was brought about through an inhibition of activation of the arachidonic acid cascade-line was tested, examining the effects of this substance on the CBF increase produced by arachidonic acid (AA) and prostacyclin (PGI2). The vasodilator response to AA, which was barely detectable at the start of the experiment at which CBF was at a physiological low level, became potentiated as the gradual increase in CBF occurred, returning to the initial magnitude after TTFD, while the vasodilator response to PGI2 remained essentially unchanged during the entire course of the experiment. It was concluded that TTFD reversed the gradual increase in CBF in the HLP through the inhibition of the arachidonic acid cascade-line activation. PMID:3912571

Matsui, K; Nakahara, H; Watanabe, H; Tamatsu, H; Nakazawa, M; Nakagawa, Y; Matsuda, H; Imai, S

1985-11-01

189

[Development of a novel artificial heart-lung system for long-term cardiopulmonary support--experimental evaluation in goats with total cardiopulmonary bypass].  

PubMed

A novel cardiopulmonary support (CPS) system for long-term use was designed and evaluated. The CPS system consists of an air-driven ventricular assist device (VAD) and a newly developed compact membrane oxygenator (MO). The VAD had proven durable and antithrombogenic in over 200 clinical uses. The membrane oxygenator, with a membrane area of 1.2 m2 and priming volume of 140 ml, is compact and designed to be interposed in the VAD conduit. It is made with a special hollow fiber membrane, in which micropores are blind-ended so that serum leakage can be prevented during prolonged use. The blood contacting surface of the MO is heparinized with a newly developed covalent bonding technique that ensures good thrombus resistance. Chronic animal experiments of total CPS were carried out for up to 336 hr in seven goats weighing from 28 to 36 kg. Venoarterial bypass was instituted with the CPS system in which all venous blood was drawn from both the right atrium and ventricle and returned to the aorta. No systemic anticoagulant therapy was used, except for a heparin-added fluid infusion to keep the monitoring lines open. Blood flow rate ranged between 107 to 130 ml/kg/min, oxygen transfer between 142 to 174 ml/min, and carbon dioxide removal between 78 to 148 ml/min. No plasma leakage was observed at the hollow fiber membrane. Substantial changes were not found in platelet count or other coagulation factors. And no perceptible thromboembolism was found at necropsy in any case. These results indicate that the system is competent enough to be used for long-term CPS, such as a bridge to lung or heart-lung transplantation. PMID:10495854

Eya, K

1999-09-01

190

Leukocyte telomeres are longer in African Americans than in whites: the National Heart, Lung, and Blood Institute Family Heart Study and the Bogalusa Heart Study  

PubMed Central

Leukocyte telomere length (LTL) is ostensibly a bio-indicator of human aging. Here we report that African Americans have longer LTL than whites. We studied cross-sectionally 2453 individuals from the National Heart, Lung, and Blood Institute (NHLBI) Family Heart Study (age = 30–93 years) and the Bogalusa Heart Study (age = 19–37 years), comprising 1742 whites and 711 African Americans. We measured LTL by Southern blots of the terminal restriction fragments length. In 234 participants, telomere repeats were also measured by quantitative polymerase chain reaction (qPCR). Adjusted for age and body mass index (BMI), the respective leukocyte telomere lengths (mean ± SEM) were considerably longer in African Americans than in whites both in the Family Heart Study (7.004 ± 0.033 kb vs. 6.735 ± 0.024 kb, p < 0.0001) and the Bogalusa Heart Study (7.923 ± 0.063 kb vs. 7.296 ± 0.039 kb, p < 0.0001). We confirmed the racial effect on LTL by qPCR (3.038 ± 0.565 T/S units for African Americans vs. 2.714 ± 0.487 T/S units for whites, p < 0.001). Cross-sectionally, sex- and BMI-adjusted LTL became shorter with age (range 19–93 years) at a steeper slope in African Americans than in whites (0.029 kb year?1 vs. 0.020 kb year?1, respectively, p = 0.0001). We suggest that racial difference in LTL arises from a host of interacting biological factors, including replication rates of hematopoietic stem cells. PMID:18462274

Hunt, Steven C; Chen, Wei; Gardner, Jeffrey P; Kimura, Masayuki; Srinivasan, Sathanur R; Eckfeldt, John H; Berenson, Gerald S; Aviv, Abraham

2008-01-01

191

The National Heart, Lung, and Blood Institute Recipient Epidemiology and Donor Evaluation Study (REDS-III): A research program striving to improve blood donor and transfusion recipient outcomes  

PubMed Central

Background The Recipient Epidemiology and Donor Evaluation Study -III (REDS-III) is a 7-year multicenter transfusion safety research initiative launched in 2011 by the National Heart, Lung, and Blood Institute. Study design The domestic component involves 4 blood centers, 12 hospitals, a data coordinating center, and a central laboratory. The international component consists of distinct programs in Brazil, China, and South Africa which involve US and in-country investigators. Results REDS-III is using two major methods to address key research priorities in blood banking/transfusion medicine. First, there will be numerous analyses of large “core” databases; the international programs have each constructed a donor/donation database while the domestic program has established a detailed research database that links data from blood donors and their donations, the components made from these donations, and data extracts from the electronic medical records of the recipients of these components. Secondly, there are more than 25 focused research protocols involving transfusion recipients, blood donors, or both that are either in progress or scheduled to begin within the next 3 years. Areas of study include transfusion epidemiology and blood utilization; transfusion outcomes; non-infectious transfusion risks; HIV-related safety issues (particularly in the international programs); emerging infectious agents; blood component quality; donor health and safety; and other donor issues. Conclusions It is intended that REDS-III serve as an impetus for more widespread recipient and linked donor-recipient research in the US as well as to help assure a safe and available blood supply in the US and in international locations. PMID:24188564

Kleinman, Steven; Busch, Michael P; Murphy, Edward L; Shan, Hua; Ness, Paul; Glynn, Simone A.

2014-01-01

192

Mean Machines.  

ERIC Educational Resources Information Center

Suggests scales as alternative representations of numerical concepts and operations that can be used as arithmetic-mean machines, adding machines, multiplication machines, and geometric-mean machines. (ASK)

Flores, Alfinio

1998-01-01

193

Simple Machines  

NSDL National Science Digital Library

Online Simple Machines Assignment OBJECTIVES: Student\\'s will be able to name and describe all seven simple machines. Students will be able to identify simple machines that they use everyday. Example: Clock = Gear INSTRUCTIONS: 1. Click on the Simple Machines Glossary page and familiarize yourself with the seven simple machines. Simple Machines Glossary Page 2. Students are to click on ...

Mr. Oldroyd

2007-09-26

194

Simple Machines  

NSDL National Science Digital Library

This activity is designed to learn about simple machines and to have fun doing so! First, use this website to learn backround information on the basics of simple machines. Try the quiz! Simple Machines Learning Site Next, play a game that tests your ability to identify simple machines.... Edheads: Simple Machines Finally, view this video to see how students your age used applied simple machines to do a cool task... Building Simple Machines: A Glass of Milk, Please ...

AWOL

2006-11-15

195

Reviving the vascular surgeon-scientist: an interim assessment of the jointly sponsored Lifeline Foundation/National Heart, Lung, and Blood Institute William J. von Liebig Mentored Clinical Scientist Development (K08) Program.  

PubMed

The Lifeline Foundation/National Heart, Lung, and Blood Institute William J. von Liebig Mentored Clinical Scientist Development (K08) Award program was established as a unique partnership to support vascular surgeon-scientists. Between 1999 and 2005, 39 applications were submitted, and the overall funding rate was 49% (14 von Liebig K08s and 5 additional NHLBI K08s). Vascular surgeon K08 recipients (median age, 38 years) had held faculty appointments for 2.5 +/- 0.4 years, with 2.6 +/- 0.2 years of previous research experience and 28.4 +/- 6.2 publications. These individuals subsequently authored 5.1 +/- 0.8 peer-reviewed publications per recipient per year, of which 35% were research and 65% were clinical. Six of seven holding the K08 over 3 years had received academic promotion, and all five completing the 5-year award had achieved independent investigator status with National Institutes of Health support. The von Liebig K08 program has therefore been an effective vehicle to stimulate research career development in the field of vascular surgery. PMID:17544018

Thompson, Robert W; Schucker, Beth; Kent, K Craig; Clowes, Alexander W; Kraiss, Larry W; Mannick, John A; Yao, James S T

2007-06-01

196

MACHINE CONTEST MACHINE VOLUME WORKSHEET  

E-print Network

MACHINE CONTEST® MACHINE VOLUME WORKSHEET Note: Each square is 1' x 1' (0.3 m x 0.3 m) (Official the footprint of your machine NOTE: If any part of the machine falls within a square, you must count the entire: _______________ (choose one: ft2 or m2 ) STEP 3: Measure the height of your machine. NOTE: The maximum height is 8' (2.4 m

Yener, Aylin

197

Simple Machines  

NSDL National Science Digital Library

At this website, EdHeads, a nonprofit, offers five interactive, animated modules to educate second- through sixth-graders about simple machines. By identifying the many machines located throughout a house, students can learn about fulcrums, wheel and axles, levers, pulleys, inclined planes, and much more. The website is equipped with simple animations to help children understand how the machines work. After students have a handle on simple machines, they can begin to see how they work together to create compound machines. The website also provides a brief glossary summarizing nine types of simple machines. This site is also reviewed in the February 18, 2005_NSDL Physical Sciences Report_.

198

Kid Machine  

NSDL National Science Digital Library

This activity is on page 3 (continued on page 2) of the pdf, part of the Simple Machines Discovery Box. In this fun activity, learners "create" a complex machine by simulating the parts in action. Learners move their bodies and make sounds as if they are individual parts of a moving machine. Then learners discover what happens when part of a machine is broken and problem solve ways to fix it.

2012-06-26

199

SIMPLE MACHINES  

NSDL National Science Digital Library

You will be learning about several types of simple machines. Have fun!! Review the first website (which is right here!! Simple machines) . It has information about simple machines. DON\\"T click until you read all directions!!! Prepare to discuss each type in class. You will need to take some basic notes about each machine, using a bubble-map format. Don\\'t forget ...

Mrs. MacHose

2007-03-10

200

Sewing Machines!!  

NSDL National Science Digital Library

Learn the Parts of a Sewing Machine This should help you understand the history of sewing machines and how they work. For this assignment, answer these questions on a sheet of paper and bring it to class. Click on this link to go to a site which will briefly explain the history of the sewing machine: wikipedia Was ...

Miss. Walker

2008-10-20

201

Electrostatic Machines  

NSDL National Science Digital Library

This website from Antonio Carlos M. De Queiroz, an associate professor at the Federal University of Rio de Janeiro, illustrates a number of different electrostatic machines. The site includes details and images of machines built by the professor as well as many other historical machines of this type. Some information is also available in Portugese.

De Queiroz, Antonio Carlos M.

202

Simple Machines  

NSDL National Science Digital Library

This is a lesson about simple machines and how they relate to robots. Learners will gain an understanding of simple machines and how they may be used in our everyday lives. Students will also have an opportunity to design a Rube Goldberg Machine of their own. This is lesson 10 of 16 in the MarsBots learning module.

2012-08-03

203

Simple Machines  

NSDL National Science Digital Library

This is an online activity about simple machines. Learners will try their hand at putting these amazing devices to work. They will use several simple machines to help "build" a tree house. This is an excellent activity to demonstrate how science - in particular, simple machines - are at work in our everyday lives.

COSI

2000-01-01

204

Pulmonary Thromboendarterectomy  

MedlinePLUS

... The operation is done using the heart-lung machine like other "open heart" operations. It is done ... most cardiac surgical procedures. With the heart-lung machine the patient's body temperature is lowered sufficiently to ...

205

The vascular surgeon-scientist: A 15-year report of the Society for Vascular Surgery Foundation/National Heart, Lung, and Blood Institute-mentored Career Development Award Program.  

PubMed

The Society for Vascular Surgery (SVS) Foundation partnered with the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH) in 1999 to initiate a competitive career development program that provides a financial supplement to surgeon-scientists receiving NIH K08 or K23 career development awards. Because the program has been in existence for 15 years, a review of the program's success has been performed. Between 1999 and 2013, 41 faculty members applied to the SVS Foundation program, and 29 from 21 different institutions were selected as awardees, resulting in a 71% success rate. Three women (10%) were among the 29 awardees. Nine awardees (31%) were supported by prior NIH F32 or T32 training grants. Awardees received their K award at an average of 3.5 years from the start of their faculty position, at the average age of 39.8 years. Thirteen awardees (45%) have subsequently received NIH R01 awards and five (17%) have received Veterans Affairs Merit Awards. Awardees received their first R01 at an average of 5.8 years after the start of their K award at the average age of 45.2 years. The SVS Foundation committed $9,350,000 to the Career Development Award Program. Awardees subsequently secured $45,108,174 in NIH and Veterans Affairs funds, resulting in a 4.8-fold financial return on investment for the SVS Foundation program. Overall, 23 awardees (79%) were promoted from assistant to associate professor in an average of 5.9 years, and 10 (34%) were promoted from associate professor to professor in an average of 5.2 years. Six awardees (21%) hold endowed professorships and four (14%) have secured tenure. Many of the awardees hold positions of leadership, including 12 (41%) as division chief and two (7%) as vice chair within a department of surgery. Eight (28%) awardees have served as president of a regional or national society. Lastly, 47 postdoctoral trainees have been mentored by recipients of the SVS Foundation Career Development Program on training grants or postdoctoral research fellowships. The SVS Foundation Career Development Program has been an effective vehicle to promote the development and independence of vascular surgeon-scientists in the field of academic vascular surgery. PMID:25814368

Kibbe, Melina R; Dardik, Alan; Velazquez, Omaida C; Conte, Michael S

2015-04-01

206

: Helmholtz machine estimation .  

E-print Network

: Helmholtz machine density estimation . . : . . . (supervised learning) , (active learning) (query learning) [1, 3]. . (unsupervised learning), . , [5]. . Helmholtz machine , . Helmholtz machine : Helmholtz machine [2] . Helmholtz machine (generative network) (recognition network) . , , . Helmholtz machine (self

207

National Heart, Lung, and Blood Institute  

E-print Network

Panel Report 3: Guidelines for the Diagnosis and Management of Asthma Full Report 2007 #12;August......................................................................14 Pathophysiologic Mechanisms in the Development of Airway Inflammation ......................16..........................................................................................................19 Implications of Inflammation for Therapy

Levin, Judith G.

208

National Heart, Lung, and Blood Institute  

MedlinePLUS

... and research projects: Spotlight On Research Fact Sheets . Funding Opportunities NOT-OD-15-073: Correction to Application ... Results Submission under FDAAA View full list of Funding Opportunities Training & Career Development The NHLBI is committed ...

209

National Heart, Lung, and Blood Institute  

E-print Network

-like sub- stance) in your blood, it builds up in the walls of your arteries. Over time, this buildup causes--the main source of cholesterol buildup and blockage in the arteries. It is optimal to have an LDL level--Being inactive is a risk factor for heart disease. Regular physical activity can help lower LDL cholesterol

Bandettini, Peter A.

210

A total heart/lung bypass simulator.  

PubMed

The often overlooked role of device design is the need to teach the optimal use of the device. A mathematical model was used in the development of the Sarns/3M SMO oxygenator, as presented at the 1985 ASAIO meeting. This model accepts inlet saturation, hemoglobin levels, and other variables, and returns output saturation, and has been verified in over 100 clinical cases. A patient oxygen consumption model including oxygen stores was developed, using clinical data based on size, temperature, and a term called "anesthesia level." This interesting factor accounts for differences between institutions. The two models were integrated with a heat exchanger model and a patient temperature model to allow accurate predictions of cooling and heating, and a hemoconcentrator model. The combination was programmed for IBM compatible computers to create a bypass simulator. A potential user can put a patient on bypass starting with any selected patient variables, track progress on a minute by minute basis, and adjust the circuit variables as dictated by his technique. The program runs in accelerated time, and accepts defaults to continue without changes as long as desired. Such a simulator is valuable for the initial introduction of the new device to experienced perfusionists, the training of potential new perfusionists, study of unusual or complex cases, the design of new devices, and even as a "track along" system during an actual clinical case. PMID:3196593

Leonard, R J

1988-01-01

211

Heart/Lung Data Center Profile  

MedlinePLUS

... holds the Scientific Registry of Transplant Recipients contract. Organ Procurement & Transplantation Network U.S. Department of Health and Human Services Health Resources and Services Administration This is ...

212

National Heart, Lung, and Blood Institute  

E-print Network

and milk products, whole grains, fish, poultry, beans, seeds, and nuts. Compared with the typical American; and red meats. This heart healthy way of eating is also lower in saturated fat, trans fat, and cholesterol and dinner the next, and add fruit at one meal or as a snack. · Increase your use of fat-free and low

Bandettini, Peter A.

213

Precision Machining  

NSDL National Science Digital Library

Basic machining processes are introduced on a Web site that is devoted to engineering fundamentals (1). Descriptions and illustrations of drilling, turning, grinding, and other common processes are provided for people with little to no prior machining knowledge. A waterjet is a non-traditional machining technology that uses high pressure streams of water with abrasive additives rather than solid cutting instruments to slice through metal and other materials. An in-depth discussion of waterjet operation and applications is available from Southern Methodist University (2). Waterjets are often cited as being much more precise than traditional machining techniques. The Waterjet Video Vault (3) contains clips of waterjet machines in action. The video of the foam cutting procedure is especially interesting, as it shows how quick and accurate the machining process can be. An online guide to cross process machining, which incorporates elements from various conventional and unconventional techniques, is provided by the Mechanical Engineering Department at Columbia University (4). Some remarkable and innovative techniques that have surfaced over the past few years are outlined, including underwater laser machining and plasma-assisted machining. Entirely different and exotic machining techniques are required for creating microelectromechanical systems (MEMS) and other extremely small devices. The Caltech Micromachining Laboratory (5) maintains an archive of research highlights and papers on its homepage, including a paper on a MEMS-driven flapping wing for a palm-sized aerial vehicle. An online article from Modern Machine Shop (6) outlines some new technologies and research in the area of high speed machining. A particularly interesting section of the article describes a system developed at the University of Florida that aims to enable micromachining to achieve rotational speeds of standard machining processes, specifically up to a half million rotations per minute. Cutting edge waterjet innovations are the subject of a February 2003 feature from a publication of the Society of Manufacturing Engineers (7). Extremely high pressure nozzles are being developed to improve cutting speed, and enhanced software for controlling machine movements is also a focus of study. This news article (8) from June 20, 2003 describes an electrochemical machining process that is being used to fabricate complex nanostructures. The work, produced by German and U.S. researchers, has the potential to compete with current lithographic processes.

Leske, Cavin.

214

Machine intelligence  

Microsoft Academic Search

Under certain conditions, we appear willing to see and interact with computing machines as though they exhibited intelligence, at least an intelligence of sorts. Using exam- ples from AI and robotics research, as well as a selection of relevant art installations and anthropological fieldwork, this paper reflects on some of our interactions with the kinds of machines we seem ready

Alex S. Taylor

2009-01-01

215

Simple Machines  

NSDL National Science Digital Library

Through a five-lesson series with five activities, students are introduced to six simple machines—inclined plane, wedge, screw, lever, pulley, wheel-and-axle—as well as compound machines, which are combinations of two or more simple machines. Once students understand about work (work = force x distance), they become familiar with the machines' mechanical advantages, and see how they make work easier. Through an introduction to compound machines, students begin to think critically about machine inventions and their pervasive roles in our lives. After learning about Rube Goldberg contraptions—absurd inventions that complete simple tasks in complicated ways—they evaluate the importance and usefulness of the many machines around them. Through the hands-on activities, students draw designs for contraptions that could move a circus elephant into a rail car, create a construction site ramp design by measuring different inclined planes and calculating the ideal vs. actual mechanical advantage of each, compare the theoretical and actual mechanical advantages of different pulley systems conceived to save a whale, build and test grape catapults made with popsicle sticks and rubber bands, and follow the steps of the engineering design process to design and build Rube Goldberg machines.

Integrated Teaching and Learning Program,

216

Simple Machines  

NSDL National Science Digital Library

How do you get a glove and a ball up to your tree house? One answer is to use a pulley. A pulley is a simple machine. In this original KET interactive, children learn about the basic workings of three simple machines.

KET

2010-11-16

217

Electric machine  

DOEpatents

An interior permanent magnet electric machine is disclosed. The interior permanent magnet electric machine comprises a rotor comprising a plurality of radially placed magnets each having a proximal end and a distal end, wherein each magnet comprises a plurality of magnetic segments and at least one magnetic segment towards the distal end comprises a high resistivity magnetic material.

El-Refaie, Ayman Mohamed Fawzi (Niskayuna, NY); Reddy, Patel Bhageerath (Madison, WI)

2012-07-17

218

Calculating machines  

NSDL National Science Digital Library

This website created by Erez Kaplan "deals mainly with the mechanical calculating machines from a collector's point of view." Included here is an historical review of calculating machines, along with Kaplan's attempt to classify the machines, a collection of old advertisements for the machines, and a brief history of calculating. The latest feature is a Java applet that lets you operate an 1885 Felt adding machine to give you a sense of the way it was used. The photos and descriptions provide insight on other gadgets such as the Pocket Cash Registers used by "the sophisticated man or woman of 1900 who had everything." The Reference section provides some resources for further reading, including numerous other personal calculator collectors sites and museums.

219

Scribbling Machines  

NSDL National Science Digital Library

In this activity, learners explore electronics and motion by making a Scribbling Machine, a motorized contraption that moves in unusual ways and leaves a mark to trace its path. It’s made from simple materials and is based on the idea of motion created by an offset motor. Try using harvested motors and switches from discarded toys and electronics to make your Scribbling Machine - this not only keeps costs down, but is a playful and inventive way to explore how everyday objects work. To take the activity further, you can also incorporate PicoCrickets to make your Scribbling Machine more intelligent and to explore computers.

Exploratorium

2013-01-30

220

Math Machines  

NSDL National Science Digital Library

The mission of the Math Machines organization is to "improve the quality of mathematical education, enhance the transfer of mathematical thinking into other classes, and increase students' ability to apply rigorous mathematics outside the classroom." Their website supports a National Science Foundation ATE grant-supported project designed to improve teaching in the areas of Mathematics, Science, and Technology at the high school and college levels. This improved learning results from using math, science, and technology principles to build and control various machines such as pointers and robots or "math machines", which are simple devices that provide an immediate, physical, dynamic expression to abstract mathematical equations. The website provides information links on Educational Theory, Classroom Activities, Project Workshops, Calculators & Programs, and Machine Construction Instructions for Building: Closed Circuits, Servo Motors, Controllers, Robot Boards and more. There is also contact information, an FAQ section, as well as upcoming events.

221

Simple Machines  

NSDL National Science Digital Library

This series of three interactive, multimedia activities introduce and demonstrate the properties of six simple machines. Specifically, the lessons show how levers, pulleys, inclined planes, screws, wheels and axles, and wedges can reduce the amount of work done by humans. After learning about the characteristics of each classification, users can try to find the simple machines that make up a lawn mower. By inspecting the mower from different angles, several simple machines are revealed and must be identified. The final activity lets users test their knowledge of the mechanics of simple machines. Following a builder through each stage of constructing a tree house, users can apply equations to determine the mechanical advantage supplied by using the tools.

222

Machine therapy  

E-print Network

Machine Therapy is a new practice combining art, design, psychoanalysis, and engineering work in ways that access and reveal the vital, though often unnoticed, relevance of people's interactions and relationships with ...

Dobson, Kelly E. (Kelly Elizabeth), 1970-

2007-01-01

223

Machine Vision  

NSDL National Science Digital Library

An overview of a generic image-based machine vision system is provided on this Web site (1). The tutorial describes the main components of such a system, how its accuracy is measured, and what scientific and industrial applications benefit from machine vision. A more technical perspective of machine vision technology is given in an online publication of the Automated Imaging Association (2). Monthly feature articles discuss breaking issues related to machine vision, and several technical papers can be downloaded, which are sorted into categories such as three dimensional imaging and nanotechnology. Researchers from the MIT's Artificial Intelligence Laboratory (3) are investigating how to enable a computer to interpret visual and audio signals from its human user. By using machine perception systems to track the user's gaze, for example, the computer could ascertain the focus of the user's attention, thereby facilitating interaction between the human and the computer. The project's homepage includes numerous research papers, as well as video demonstrations of some of its systems. Machine vision is also finding its way into vehicles. A March 2003 news article (4) highlights a field test in Michigan of a collision avoidance system that uses, among other things, machine vision to warn drivers that they are approaching a slower or stopped object too quickly. The 3D Computer Vision Group at Carnegie Mellon University (5) is involved in several projects, including three dimensional object recognition and humanoid robot vision. Many of the group's recent publications are available for download. NASA's Mars Exploration Rovers, the second of which was launched in July 2003, have vision systems that will let them safely navigate rough terrain. These systems are described in this conference paper (6), including specifics of the stereo vision algorithm and insights into future missions. A new implementation of machine vision comes from a former researcher from Cambridge University. His shape recognition system, which is detailed in this news article (7), is reportedly much more related to human visual processes than existing techniques. For additional developments related to this evolving technology, Machine Vision News (8) has information about worldwide research and new applications of machine vision systems.

Leske, Cavin.

224

Culture Machine  

NSDL National Science Digital Library

Culture Machine is a new, refereed, electronic journal encompassing cultural studies and cultural theory. The international editorial board of the interactive journal aims to "generat[e] research in culture and theory" by promoting and publishing "the most provocative of new work." The theme of the inaugural issue is Taking Risks with the Future. Content includes articles such as Life After Death of the Text by Johan Fornas, Cultural Studies in the Clouds: Mourning for Detail by Tadeusz Slawek, and The Future States of Politics by Kenneth Surin. Culture Machine is hosted by the University of Teesside, England.

225

Workout Machine  

NASA Technical Reports Server (NTRS)

The Orbotron is a tri-axle exercise machine patterned after a NASA training simulator for astronaut orientation in the microgravity of space. It has three orbiting rings corresponding to roll, pitch and yaw. The user is in the middle of the inner ring with the stomach remaining in the center of all axes, eliminating dizziness. Human power starts the rings spinning, unlike the NASA air-powered system. Marketed by Fantasy Factory (formerly Orbotron, Inc.), the machine can improve aerobic capacity, strength and endurance in five to seven minute workouts.

1995-01-01

226

Decoding Machine  

NSDL National Science Digital Library

In this math lesson, learners explore variables and their uses. Learners pretend to be FBI agents and make a TOP SECRET tool that enables them to decode and find the values of hidden messages and words. Learners make their simple "decoding machines" out of paper and tape.

Utah LessonPlans

2012-10-22

227

Function Machine  

NSDL National Science Digital Library

This Java applet allows learners to explore simple linear functions. Students determine the algebraic form of a linear equation by entering inputs into the machine and by looking for patterns in the outputs. The function rules available are: integers from -10 to 10 are either added to, subtracted from, or multiplied by the input x to yield the output y.

2011-01-01

228

Wacky Machines  

ERIC Educational Resources Information Center

Collectors everywhere know that local antique shops and flea markets are treasure troves just waiting to be plundered. Science teachers might take a hint from these hobbyists, for the next community yard sale might be a repository of old, quirky items that are just the things to get students thinking about simple machines. By introducing some…

Fendrich, Jean

2002-01-01

229

Leonardo's Machines  

NSDL National Science Digital Library

This Science NetLinks lesson will highlight some of Leonardo da Vinci's futuristic inventions, introducing the elements of machines. Through the use of student interactives, this lesson provides an interesting context in which students can begin to develop their ideas about the uniqueness of humans in the natural world.

Science Netlinks

2003-03-05

230

A Generalized Deletion Machine  

E-print Network

In this work we prescribe a more generalized quantum-deleting machine (input state dependent). The fidelity of deletion is dependent on some machine parameters such that on alteration of machine parameters we get back to standard deleting machines. We also carried out a various comparative study of various kinds of quantum deleting machines. We also plotted graphs, making a comparative study of fidelity of deletion of the deletion machines, obtained as particular cases on changing the machine parameters of our machine.

Indranil Chakrabarty; Satyabrata Adhikari

2005-11-22

231

Drilling Machines: Vocational Machine Shop.  

ERIC Educational Resources Information Center

The lessons and supportive information in this field tested instructional block provide a guide for teachers in developing a machine shop course of study in drilling. The document is comprised of operation sheets, information sheets, and transparency masters for 23 lessons. Each lesson plan includes a performance objective, material and tools,…

Thomas, John C.

232

State-Machine Replication  

E-print Network

State-Machine Replication #12;The Problem Clients Server #12;The Problem Clients Server #12;The (state machine) #12;The Solution 1. Make server deterministic (state machine) State machine #12;The Solution 1. Make server deterministic (state machine) 2. Replicate server State machines #12;The Solution 1

Venkataramani, Arun

233

Simple Machines  

NSDL National Science Digital Library

The goals for this introduction activity to Simple Machines are.: - Generate scientific questions about the world based on observation - Design and conduct scientific investigations - Use tools and equipment appropriate to scientific investigations - Use sources of information in support of scientific investigation - Write and follow procedures in the form of step-by-step instructions, formulas, flow diagram, and sketches - Show how common themes of science, mathematics, and technology apply in real-world contexts - Recognize the contributions made in science by cultures and individuals of diverse backgrounds - Design strategies for moving objects by application of forces, including the use of simple machines MERC Online Reviewer Comments: Good computer activities for under-represented students who want to pursue manufacturing education. Distance Learning is a plus.

Wakild, Terri

234

Living Machines  

Microsoft Academic Search

\\u000a Ecological studies have revealed that nature has an in-built system to restore itself, thereby sustaining its continuity.\\u000a In other words, natural ecosystems can act as “Living Machines” in keeping the ecosystems habitable. The biological communities\\u000a – microbes, plants, and animals – serve as the driving force of several living technological innovations – constructed wetlands,\\u000a Lake Restores, Eco-Restorers, and Reedbeds. These

Yung-Tse Hung; Joseph F. Hawumba; Lawrence K. Wang

235

Learning about Simple Machines  

NSDL National Science Digital Library

This activity is designed to learn about simple machines and to have fun doing so! First, use this website to learn backround information on the basics of simple machines. Try the quiz! Simple Machines Learning Site Next, play a game that tests your ability to identify simple machines.... Edheads: Simple Machines Finally, view this video to see how students your age used applied simple machines to do a cool task... Building Simple Machines: A Glass of Milk, Please ...

Mrs. Keller

2010-01-17

236

Machine Design  

NSDL National Science Digital Library

This website, the homepage of Machine Design.com, contains resources on a variety of information for engineers and technicians related to devices, components, design applications, products, and systems in the manufacturing technology sector. The site also features a CAD library, eBooks, audiovisual aids, webinars, whitepapers and a reference center. Some of the resources require a free login. The page offers an RSS feed to keep users up to date on new resources. A free login may be required to access some of these items.

237

Function Machine  

NSDL National Science Digital Library

This Java activity for the interactive white board (free access with registration) provides learners an opportunity to explore number functions and to predict outcomes. Teachers set the desired function from the drop-down list (double it, halve it, add 1, subtract 1, add 10, or subtract 10) and choose the start number from 1-20. Students are asked to predict the outcome before asking the machine to go. There is an option to hide the function so the teacher can ask students to work out what operation is being used to get from the starting number to the number generated.

2012-07-19

238

Course info Machine Learning  

E-print Network

Course info Machine Learning Real life problems Lecture 1: Machine Learning Problem Qinfeng (Javen) Shi 28 July 2014 Intro. to Stats. Machine Learning COMP SCI 4401/7401 Qinfeng (Javen) Shi Lecture 1: Machine Learning Problem #12;Course info Machine Learning Real life problems Table of Contents I 1 Course

Shi, Qinfeng "Javen"

239

Mind & Machine  

NSDL National Science Digital Library

Mind & Machine is a weekly column provided by Ashley Dunn for the New York Times Cybertimes that discusses topics related to computing, technology, and the Internet. Recent columns have addressed the topics of the development of Internet telephony, possible futures of user interfaces, the history of technology and standards, and the Internet as a vehicle for community. Articles are well written, opinionated, and thought provoking. Mr. Dunn is a free lance writer who has written for such papers as the New York Times, the Los Angeles Times, the Seattle Post-Intelligencer, and the South China Morning Post. Note that the site is available only upon registration and is free of charge only in the US.

Dunn, Ashley.

240

Socially guided machine learning  

E-print Network

Social interaction will be key to enabling robots and machines in general to learn new tasks from ordinary people (not experts in robotics or machine learning). Everyday people who need to teach their machines new things ...

Thomaz, Andrea Lockerd

2006-01-01

241

Simple Machines - Mechanical Advantage  

NSDL National Science Digital Library

This video uses working simple machines to demonstrate how to calculate mechanical advantage. Suitable for any school program involving simple machines. Demonstrates pulley systems including a chain block.

2007-01-01

242

Parallel-machine rescheduling with machine disruptions  

Microsoft Academic Search

In this study we consider a rescheduling problem on identical parallel machines. The rescheduling is undertaken because of a period of unavailability on one of the machines. We consider the total flow time as an efficiency measure and stability is gauged in terms of the number of jobs processed on different machines in the original and new schedules. We show

Meral Azizoglu; Oguzhan Alagöz

2005-01-01

243

DC Machine  

NSDL National Science Digital Library

The effect of the commutator is to produce a fixed spatial distribution of current directions in the armature conductors (shown as blue & green circles) independent of shaft rotation. The field created by these currents (armature reaction) is vertically directed along the quadrature axis. The field established by the excitation of the stator poles is directed along the horizontal direct axis. This package presents computer models of electric machines based on the space vector formulation leading to the assessment of the dynamic performance of open- and closed-loopac and dc drive systems. The Simulink/Matlab implementation is adopted because of its inherent integration of vectorized system representations in block diagram form, of numerical analysis methods, of graphical portrayal of time evolutions of signals combined with the simple realization of the functionality of controllers and power electronic excitations. The development of Simulink models of drive assemblies is a relatively simple task consisting of combining input-output block representation of the various components making up the system; these blocks can readily be reused (utilizing standard copy-and-paste techniques) to modify the system components or the configuration of the system. This approach provides a powerful design tool because of the ease of observing the effects of parameters modifications and of differing system configurations and control strategies.

Riaz, Mahmoud

244

DRILLING MACHINES GENERAL INFORMATION  

E-print Network

or angled drilled. The base of the drilling machine supports the entire machine and when bolted to the floor parts. Follow the manufacturer's manual for proper lubrication methods. Clean each machine after useTC 9-524 Chapter 4 DRILLING MACHINES GENERAL INFORMATION PURPOSE This chapter contains basic

Gellman, Andrew J.

245

Extreme Kicking Machine  

NSDL National Science Digital Library

In this design challenge activity follow up to "Kicking Machine", learners add a hands-free feature to their Kicking Machine. Learners modify their kicking machine to have it either release the pendulum or rubber band while standing three feet away or have it automatically feed balls into the kicking machine, one after another. They must figure out how to integrate the new feature into the existing structure and use the design process to make sure the modified kicking machine works properly. Educators can use this activity to demonstrate simple machines and kinetic/potential energy.

2012-08-20

246

Stirling machine operating experience  

NASA Technical Reports Server (NTRS)

Numerous Stirling machines have been built and operated, but the operating experience of these machines is not well known. It is important to examine this operating experience in detail, because it largely substantiates the claim that Stirling machines are capable of reliable and lengthy lives. The amount of data that exists is impressive, considering that many of the machines that have been built are developmental machines intended to show proof of concept, and were not expected to operate for any lengthy period of time. Some Stirling machines (typically free-piston machines) achieve long life through non-contact bearings, while other Stirling machines (typically kinematic) have achieved long operating lives through regular seal and bearing replacements. In addition to engine and system testing, life testing of critical components is also considered.

Ross, Brad; Dudenhoefer, James E.

1991-01-01

247

Women, Men, and Machines.  

ERIC Educational Resources Information Center

Data from the first national study of technological change show that proportionately more women than men operate machines, are more exposed to machines that have alienating effects, and suffer more from the negative effects of technological change. (Author/SSH)

Form, William; McMillen, David Byron

1983-01-01

248

Machine protection systems  

E-print Network

A summary of the Machine Protection System of the LHC is given, with particular attention given to the outstanding issues to be addressed, rather than the successes of the machine protection system from the 2009 run. In particular, the issues of Safe Machine Parameter system, collimation and beam cleaning, the beam dump system and abort gap cleaning, injection and dump protection, and the overall machine protection program for the upcoming run are summarised.

Macpherson, A L

2010-01-01

249

The Advantage of Machines  

NSDL National Science Digital Library

In this lesson, students learn about work as defined by physical science and see that work is made easier through the use of simple machines. Already encountering simple machines everyday, students will be learn about their widespread uses in improving everyday life. This lesson serves as the starting point for the Simple Machines Unit.

Integrated Teaching and Learning Program,

250

Drilling mud cleaning machine  

Microsoft Academic Search

This patent describes a multiple-function cleaning, desilting and desanding machine for cleaning drilling muds which contain unwanted solid waste materials entrained during drilling processes. The machine comprises: supportive frame means adapted to be disposed upon a supportive surface for securely positioning the machine at a selected drilling site; a cyclone chamber having means for receiving dirty drilling mud from a

W. L. Spruiell; J. L. Spruiell

1987-01-01

251

Wind motor machine  

Microsoft Academic Search

An improved wind motor machine having a wind rotor rotatable about a vertical axis. The rotor core body of the machine is provided with convexly curved wind application surfaces and coacting outer wing bodies having load supporting airplane wing-shaped cross-sections. The efficiency of the machine is improved by means of stream guiding bodies disposed in the intermediate space between the

Goedecke

1984-01-01

252

Millikelvin Lab Machine Shop  

E-print Network

Millikelvin Lab OP105­112 Machine Shop OP132 Resistive Magnet Shop CICC Winding Area Transformers This building is home to the Millikelvin lab, the control room, the resistive magnet and machine shops, the CICC@magnet.fsu.edu (850) 644-4378 (850) 644-0534 2 MACHINE SHOP OP132 Vaughan Williams (A114*) williams

McQuade, D. Tyler

253

Review on ultrasonic machining  

Microsoft Academic Search

Ultrasonic machining is of particular interest for the cutting of non-conductive, brittle workpiece materials such as engineering ceramics. Unlike other non-traditional processes such as laser beam, and electrical discharge machining, etc., ultrasonic machining does not thermally damage the workpiece or appear to introduce significant levels of residual stress, which is important for the survival of brittle materials in service. The

T. B. Thoe; D. K. Aspinwall; M. L. H. Wise

1998-01-01

254

Your Sewing Machine.  

ERIC Educational Resources Information Center

The programed instruction manual is designed to aid the student in learning the parts, uses, and operation of the sewing machine. Drawings of sewing machine parts are presented, and space is provided for the student's written responses. Following an introductory section identifying sewing machine parts, the manual deals with each part and its…

Peacock, Marion E.

255

Find the Simple Machines  

NSDL National Science Digital Library

This is a web activity about simple machines. Learners will explore a lawn mower and identify six different simple machines which work together to help make our lives easier. This is an excellent activity for exploring how simple machines, and science in general, apply to learners' everyday lives.

COSI

2000-01-01

256

Apprentice Machine Theory Outline.  

ERIC Educational Resources Information Center

This volume contains outlines for 16 courses in machine theory that are designed for machine tool apprentices. Addressed in the individual course outlines are the following topics: basic concepts; lathes; milling machines; drills, saws, and shapers; heat treatment and metallurgy; grinders; quality control; hydraulics and pneumatics;…

Connecticut State Dept. of Education, Hartford. Div. of Vocational-Technical Schools.

257

Machine tool locator  

DOEpatents

Machine tools can be accurately measured and positioned on manufacturing machines within very small tolerances by use of an autocollimator on a 3-axis mount on a manufacturing machine and positioned so as to focus on a reference tooling ball or a machine tool, a digital camera connected to the viewing end of the autocollimator, and a marker and measure generator for receiving digital images from the camera, then displaying or measuring distances between the projection reticle and the reference reticle on the monitoring screen, and relating the distances to the actual position of the autocollimator relative to the reference tooling ball. The images and measurements are used to set the position of the machine tool and to measure the size and shape of the machine tool tip, and examine cutting edge wear. patent

Hanlon, John A. (Los Alamos, NM); Gill, Timothy J. (Stanley, NM)

2001-01-01

258

Machining: An Introduction  

NSDL National Science Digital Library

Basic machining processes are introduced on this site that is devoted to engineering fundamentals. Descriptions and illustrations of drilling, turning, grinding, and other common processes are provided for people with little to no prior machining knowledge. A waterjet is a non-traditional machining technology that uses high pressure streams of water with abrasive additives rather than solid cutting instruments to slice through metal and other materials.

259

Quantum Learning Machine  

E-print Network

We propose a novel notion of a quantum learning machine for automatically controlling quantum coherence and for developing quantum algorithms. A quantum learning machine can be trained to learn a certain task with no a priori knowledge on its algorithm. As an example, it is demonstrated that the quantum learning machine learns Deutsch's task and finds itself a quantum algorithm, that is different from but equivalent to the original one.

Jeongho Bang; James Lim; M. S. Kim; Jinhyoung Lee

2008-03-31

260

Chaotic Boltzmann machines  

PubMed Central

The chaotic Boltzmann machine proposed in this paper is a chaotic pseudo-billiard system that works as a Boltzmann machine. Chaotic Boltzmann machines are shown numerically to have computing abilities comparable to conventional (stochastic) Boltzmann machines. Since no randomness is required, efficient hardware implementation is expected. Moreover, the ferromagnetic phase transition of the Ising model is shown to be characterised by the largest Lyapunov exponent of the proposed system. In general, a method to relate probabilistic models to nonlinear dynamics by derandomising Gibbs sampling is presented. PMID:23558425

Suzuki, Hideyuki; Imura, Jun-ichi; Horio, Yoshihiko; Aihara, Kazuyuki

2013-01-01

261

Chaotic Boltzmann machines.  

PubMed

The chaotic Boltzmann machine proposed in this paper is a chaotic pseudo-billiard system that works as a Boltzmann machine. Chaotic Boltzmann machines are shown numerically to have computing abilities comparable to conventional (stochastic) Boltzmann machines. Since no randomness is required, efficient hardware implementation is expected. Moreover, the ferromagnetic phase transition of the Ising model is shown to be characterised by the largest Lyapunov exponent of the proposed system. In general, a method to relate probabilistic models to nonlinear dynamics by derandomising Gibbs sampling is presented. PMID:23558425

Suzuki, Hideyuki; Imura, Jun-ichi; Horio, Yoshihiko; Aihara, Kazuyuki

2013-01-01

262

Hearts, Lungs, and Children: A Physiologist Returns To Kindergarten.  

ERIC Educational Resources Information Center

Details the experiences of a physiologist introducing kindergartners to the basics of cardiorespiratory physiology including pulmonary ventilation and circulatory transport of oxygen. Describes the demonstration and how it enables children to participate in scientific inquiry. Contains 17 references. (DDR)

Curran-Everett, Douglas

1995-01-01

263

14. Interior, Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

14. Interior, Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific Railroad Carlin Shops, view to north (90mm lens). - Southern Pacific Railroad, Carlin Shops, Roundhouse Machine Shop Extension, Foot of Sixth Street, Carlin, Elko County, NV

264

BRITISH MOLDING MACHINE, PBQ AUTOMATIC COPE AND DRAG MOLDING MACHINE ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

BRITISH MOLDING MACHINE, PBQ AUTOMATIC COPE AND DRAG MOLDING MACHINE MAKES BOTH MOLD HALVES INDIVIDUALLY WHICH ARE LATER ROTATED, ASSEMBLED, AND LOWERED TO POURING CONVEYORS BY ASSISTING MACHINES. - Southern Ductile Casting Company, Casting, 2217 Carolina Avenue, Bessemer, Jefferson County, AL

265

Diamond machine tool face lapping machine  

DOEpatents

An apparatus for shaping, sharpening and polishing diamond-tipped single-point machine tools. The isolation of a rotating grinding wheel from its driving apparatus using an air bearing and causing the tool to be shaped, polished or sharpened to be moved across the surface of the grinding wheel so that it does not remain at one radius for more than a single rotation of the grinding wheel has been found to readily result in machine tools of a quality which can only be obtained by the most tedious and costly processing procedures, and previously unattainable by simple lapping techniques.

Yetter, H.H.

1985-05-06

266

Machine monitoring for turning machine. [Hemispherical workpieces  

SciTech Connect

This paper describes activities that have occurred to date on a prototype system used to monitor the status of a turning operation that provides high qualtiy hemispherical workpieces. Data are collected from a variety of sensors and used to judge part quality in real time through a comparison with historical data from an on-line computer data base. The techniques developed on this system will be implemented in a precision flexible manufacturing cell that will operate in partly untended mode. A combination of on-machine monitoring and off-machine gaging will ensure that workpieces leaving the cell have in-tolerance characteristics.

Barkman, W.E.; Wieger, G.P.; Woodard, L.M.

1984-01-10

267

Stirling machine operating experience  

SciTech Connect

Numerous Stirling machines have been built and operated, but the operating experience of these machines is not well known. It is important to examine this operating experience in detail, because it largely substantiates the claim that stirling machines are capable of reliable and lengthy operating lives. The amount of data that exists is impressive, considering that many of the machines that have been built are developmental machines intended to show proof of concept, and are not expected to operate for lengthy periods of time. Some Stirling machines (typically free-piston machines) achieve long life through non-contact bearings, while other Stirling machines (typically kinematic) have achieved long operating lives through regular seal and bearing replacements. In addition to engine and system testing, life testing of critical components is also considered. The record in this paper is not complete, due to the reluctance of some organizations to release operational data and because several organizations were not contacted. The authors intend to repeat this assessment in three years, hoping for even greater participation.

Ross, B. [Stirling Technology Co., Richland, WA (United States); Dudenhoefer, J.E. [Lewis Research Center, Cleveland, OH (United States)

1994-09-01

268

Semantics via Machine Translation  

ERIC Educational Resources Information Center

Recent experiments in machine translation have given the semantic elements of collocation in Russian more objective criteria. Soviet linguists in search of semantic relationships have attempted to devise a semantic synthesis for construction of a basic language for machine translation. One such effort is summarized. (CHK)

Culhane, P. T.

1977-01-01

269

Machine Translation Project  

NASA Technical Reports Server (NTRS)

The characteristics and capabilities of existing machine translation systems were examined and procurement recommendations were developed. Four systems, SYSTRAN, GLOBALINK, PC TRANSLATOR, and STYLUS, were determined to meet the NASA requirements for a machine translation system. Initially, four language pairs were selected for implementation. These are Russian-English, French-English, German-English, and Japanese-English.

Bajis, Katie

1993-01-01

270

Automatic soldering machine  

NASA Technical Reports Server (NTRS)

Fully-automatic tube-joint soldering machine can be used to make leakproof joints in aluminum tubes of 3/16 to 2 in. in diameter. Machine consists of temperature-control unit, heater transformer and heater head, vibrator, and associated circuitry controls, and indicators.

Stein, J. A.

1974-01-01

271

Simple Machines Made Simple.  

ERIC Educational Resources Information Center

Simple machines have become a lost point of study in elementary schools as teachers continue to have more material to cover. This manual provides hands-on, cooperative learning activities for grades three through eight concerning the six simple machines: wheel and axle, inclined plane, screw, pulley, wedge, and lever. Most activities can be…

St. Andre, Ralph E.

272

Compound taper milling machine  

NASA Technical Reports Server (NTRS)

Simple, inexpensive milling machine tapers panels from a common apex to a uniform height at panel edge regardless of the panel perimeter configuration. The machine consists of an adjustable angled beam upon which the milling tool moves back and forth above a rotatable table upon which the workpiece is held.

Campbell, N. R.

1969-01-01

273

Simple Machine Junk Cars  

ERIC Educational Resources Information Center

During the month of May, the author's eighth-grade physical science students study the six simple machines through hands-on activities, reading assignments, videos, and notes. At the end of the month, they can easily identify the six types of simple machine: inclined plane, wheel and axle, pulley, screw, wedge, and lever. To conclude this unit,…

Herald, Christine

2010-01-01

274

Dictionary machine (for VLSI)  

SciTech Connect

The authors present the design of a dictionary machine that is suitable for VLSI implementation, and discusses how to realize this implementation efficiently. The machine supports the operations of search, insert, delete, and extractment on an arbitrary ordered set. Each of these operations takes time o(logn), where n is the number of entries present when the operation is performed. Moreover, arbitrary sequences of these instructions can be pipelined through the machine at a constant rate (i.e. independent of n and the capacity of the machine). The time o(logn) is an improvement over previous VLSI designs of dictionary machines which require time o(log n) per operation, where n is the maximum number of keys that can be stored. 10 references.

Ottmann, T.A.; Rosenberg, A.L.; Stockmeyer, L.J.

1982-09-01

275

From Reduction Machines To Narrowing Machines  

Microsoft Academic Search

Narrowing, the evaluation mechanism of functional logic languages, can be seen as a generalizationof reduction, the evaluation mechanism of purely functional languages. The unidirectionalpattern matching, which is used for parameter passing in functional languages, is simplyreplaced by the bidirectional unification known from logic programming languages. We showin this paper, how to extend a reduction machine, that has been designed for

Rita Loogen; RWTH Aachen

1991-01-01

276

Machine Learning and Radiology  

PubMed Central

In this paper, we give a short introduction to machine learning and survey its applications in radiology. We focused on six categories of applications in radiology: medical image segmentation, registration, computer aided detection and diagnosis, brain function or activity analysis and neurological disease diagnosis from fMR images, content-based image retrieval systems for CT or MRI images, and text analysis of radiology reports using natural language processing (NLP) and natural language understanding (NLU). This survey shows that machine learning plays a key role in many radiology applications. Machine learning identifies complex patterns automatically and helps radiologists make intelligent decisions on radiology data such as conventional radiographs, CT, MRI, and PET images and radiology reports. In many applications, the performance of machine learning-based automatic detection and diagnosis systems has shown to be comparable to that of a well-trained and experienced radiologist. Technology development in machine learning and radiology will benefit from each other in the long run. Key contributions and common characteristics of machine learning techniques in radiology are discussed. We also discuss the problem of translating machine learning applications to the radiology clinical setting, including advantages and potential barriers. PMID:22465077

Wang, Shijun; Summers, Ronald M.

2012-01-01

277

DNA-based machines.  

PubMed

The base sequence in nucleic acids encodes substantial structural and functional information into the biopolymer. This encoded information provides the basis for the tailoring and assembly of DNA machines. A DNA machine is defined as a molecular device that exhibits the following fundamental features. (1) It performs a fuel-driven mechanical process that mimics macroscopic machines. (2) The mechanical process requires an energy input, "fuel." (3) The mechanical operation is accompanied by an energy consumption process that leads to "waste products." (4) The cyclic operation of the DNA devices, involves the use of "fuel" and "anti-fuel" ingredients. A variety of DNA-based machines are described, including the construction of "tweezers," "walkers," "robots," "cranes," "transporters," "springs," "gears," and interlocked cyclic DNA structures acting as reconfigurable catenanes, rotaxanes, and rotors. Different "fuels", such as nucleic acid strands, pH (H?/OH?), metal ions, and light, are used to trigger the mechanical functions of the DNA devices. The operation of the devices in solution and on surfaces is described, and a variety of optical, electrical, and photoelectrochemical methods to follow the operations of the DNA machines are presented. We further address the possible applications of DNA machines and the future perspectives of molecular DNA devices. These include the application of DNA machines as functional structures for the construction of logic gates and computing, for the programmed organization of metallic nanoparticle structures and the control of plasmonic properties, and for controlling chemical transformations by DNA machines. We further discuss the future applications of DNA machines for intracellular sensing, controlling intracellular metabolic pathways, and the use of the functional nanostructures for drug delivery and medical applications. PMID:24647836

Wang, Fuan; Willner, Bilha; Willner, Itamar

2014-01-01

278

Machine Tool Software  

NASA Technical Reports Server (NTRS)

A NASA-developed software package has played a part in technical education of students who major in Mechanical Engineering Technology at William Rainey Harper College. Professor Hack has been using (APT) Automatically Programmed Tool Software since 1969 in his CAD/CAM Computer Aided Design and Manufacturing curriculum. Professor Hack teaches the use of APT programming languages for control of metal cutting machines. Machine tool instructions are geometry definitions written in APT Language to constitute a "part program." The part program is processed by the machine tool. CAD/CAM students go from writing a program to cutting steel in the course of a semester.

1988-01-01

279

Virtual Turing Machine 2  

NSDL National Science Digital Library

A Turing machine is theoretical computer consisting of a finite set of internal states, a finite alphabet that includes a blank symbol, and a finite set of instructions. It has a physical head and a physical infinitely long tape, which is divided into cells. The cell values consist of the alphabet. The tape has a finite number of non-blank cells. The head can read and write to the cells and move the tape one cell to the left and one cell to the right. The Virtual Turing Machine lets you input tape values and an instruction set to see the output of a turing machine.

Paul R. C. Ming

280

Engineering: Simple Machines  

NSDL National Science Digital Library

Simple machines are devices with few or no moving parts that make work easier. Students are introduced to the six types of simple machines — the wedge, wheel and axle, lever, inclined plane, screw, and pulley — in the context of the construction of a pyramid, gaining high-level insights into tools that have been used since ancient times and are still in use today. In two hands-on activities, students begin their own pyramid design by performing materials calculations, and evaluating and selecting a construction site. The six simple machines are examined in more depth in subsequent lessons in this unit.

2014-09-18

281

16. Interior, Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

16. Interior, Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific Railroad Carlin Shops, view to south (90mm lens). Note the large segmental-arched doorway to move locomotives in and out of Machine Shop. - Southern Pacific Railroad, Carlin Shops, Roundhouse Machine Shop Extension, Foot of Sixth Street, Carlin, Elko County, NV

282

Microcircuit-cleaning machine  

NASA Technical Reports Server (NTRS)

Circuit shaker removes loose particles from hybrid microcircuit packages. Machine can reduce rejections from particle impact noise determination (PIND) tests to less than 7 percent. Shaker is easily constructed and could be manufactured for distribution as kit.

Robinson, W. W.; Williamson, J. C.

1978-01-01

283

Machine For Grinding Fog  

E-print Network

Machine For Grinding Fog, an exhibition of stop motion animated films, revolves around three primary concerns: relationships, psychological or subjective reality, and relativity. Rooted within concerns of faith, personal ethics, and a re...

Ward, Nicholas Adam

2010-04-30

284

Machine Translation for Twitter   

E-print Network

We carried out a study in which we explored the feasibility of machine translation for Twitter for the language pair English and German. As a first step we created a small bilingual corpus of 1,000 tweets. Using this ...

Jehl, Laura Elisabeth

2010-11-24

285

Machine Learning: Introduction and  

E-print Network

to Statistical Machine Learning" What is Learning? · "Learning is making useful changes in our minds" ­ Marvin Minsky · "Learning is constructing or modifying representations of what is being experienced" ­ Ryszard

Dyer, Charles R.

286

Linear Function Machine  

NSDL National Science Digital Library

This activity allows the user to explore simple linear functions. This Java applet requires a Java-capable browser. If you don't see the applet Java may not be functional in your browser or on your machine.

The Shodor Education Foundation, Inc.

2007-12-12

287

Tunnel boring machine  

SciTech Connect

A tunnel boring machine for controlled boring of a curvilinear tunnel including a rotating cutter wheel mounted on the forward end of a thrust cylinder assembly having a central longitudinal axis aligned with the cutter wheel axis of rotation; the thrust cylinder assembly comprising a cylinder barrel and an extendable and retractable thrust arm received therein. An anchoring assembly is pivotally attached to the rear end of the cylinder barrel for anchoring the machine during a cutting stroke and providing a rear end pivot axis during curved cutting strokes. A pair of laterally extending, extendable and retractable arms are fixedly mounted at a forward portion of the cylinder barrel for providing lateral displacement in a laterally curved cutting mode and for anchoring the machine between cutting strokes and during straight line boring. Forward and rear transverse displacement and support assemblies are provided to facilitate cutting in a transversely curved cutting mode and to facilitate machine movement between cutting strokes.

Snyder, L. L.

1985-07-09

288

Design of Vitrification Machine  

E-print Network

and unreliable process. Moreover, there is a lack of standardization in the methods for preparing cells and biological material for the vitrification process. The purpose of the Vitrification Machine is to greatly simplify the process by making it faster, more...

McDonald, Todd William

2009-11-30

289

Positive Linear Function Machine  

NSDL National Science Digital Library

Students investigate linear functions with positive slopes by trying to guess the slope and intercept from inputs and outputs. Positive Linear Function Machine is one of the Interactivate assessment explorers.

290

Human and Machine Intelligence  

Microsoft Academic Search

In his 1950 Mind paper, Alan Turing reframed the question of whether machines could think as an operational or behavioral question: Could a computer be built that was indistinguishable from people in playing the \\

Barbara Grosz; Edward A. Feigenbaum; Marvin Minsky; Judea Pearl; Raj Reddy

2012-01-01

291

15 CFR 700.31 - Metalworking machines.  

Code of Federal Regulations, 2013 CFR

...and tapping machines Electrical discharge, ultrasonic and chemical erosion machines Forging machinery and hammers Gear cutting...machines Manual presses Mechanical presses, power driven Milling machines Miscellaneous machine tools Miscellaneous...

2013-01-01

292

15 CFR 700.31 - Metalworking machines.  

Code of Federal Regulations, 2014 CFR

...and tapping machines Electrical discharge, ultrasonic and chemical erosion machines Forging machinery and hammers Gear cutting...machines Manual presses Mechanical presses, power driven Milling machines Miscellaneous machine tools Miscellaneous...

2014-01-01

293

15 CFR 700.31 - Metalworking machines.  

Code of Federal Regulations, 2012 CFR

...and tapping machines Electrical discharge, ultrasonic and chemical erosion machines Forging machinery and hammers Gear cutting...machines Manual presses Mechanical presses, power driven Milling machines Miscellaneous machine tools Miscellaneous...

2012-01-01

294

15 CFR 700.31 - Metalworking machines.  

Code of Federal Regulations, 2010 CFR

...and tapping machines Electrical discharge, ultrasonic and chemical erosion machines Forging machinery and hammers Gear cutting...machines Manual presses Mechanical presses, power driven Milling machines Miscellaneous machine tools Miscellaneous...

2010-01-01

295

15 CFR 700.31 - Metalworking machines.  

Code of Federal Regulations, 2011 CFR

...and tapping machines Electrical discharge, ultrasonic and chemical erosion machines Forging machinery and hammers Gear cutting...machines Manual presses Mechanical presses, power driven Milling machines Miscellaneous machine tools Miscellaneous...

2011-01-01

296

[A new machinability test machine and the machinability of composite resins for core built-up].  

PubMed

A new machinability test machine especially for dental materials was contrived. The purpose of this study was to evaluate the effects of grinding conditions on machinability of core built-up resins using this machine, and to confirm the relationship between machinability and other properties of composite resins. The experimental machinability test machine consisted of a dental air-turbine handpiece, a control weight unit, a driving unit of the stage fixing the test specimen, and so on. The machinability was evaluated as the change in volume after grinding using a diamond point. Five kinds of core built-up resins and human teeth were used in this study. The machinabilities of these composite resins increased with an increasing load during grinding, and decreased with repeated grinding. There was no obvious correlation between the machinability and Vickers' hardness; however, a negative correlation was observed between machinability and scratch width. PMID:11496409

Iwasaki, N

2001-06-01

297

Weka Machine Learning Project  

NSDL National Science Digital Library

If you are inspired to try the process, the Weka Machine Learning Project from Waikato University offers open source software that can be used for data mining tasks. Visitors can also find the projects 1993 to 2006 publications, many of which are available for free in as PDFs. The "related" section offers a number of links to further information on topics such as artificial intelligence and machine learning.

298

Pipe cleaning machine  

Microsoft Academic Search

This is a semiautomatic machine for removing rust, mud, and paraffin from the interior and exterior of well pipe or tubing to recondition it for further use. Loading, cleaning and re-racking is carried out by a single operator. The machine has a rectangular, box-like frame which consists of 3 sub-sections and includes a loading rack located on one side of

1965-01-01

299

Doubly fed induction machine  

DOEpatents

An electro-mechanical energy conversion system coupled between an energy source and an energy load including an energy converter device having a doubly fed induction machine coupled between the energy source and the energy load to convert the energy from the energy source and to transfer the converted energy to the energy load and an energy transfer multiplexer coupled to the energy converter device to control the flow of power or energy through the doubly fed induction machine.

Skeist, S. Merrill; Baker, Richard H.

2005-10-11

300

Metalworking and machining fluids  

DOEpatents

Improved boron-based metal working and machining fluids. Boric acid and boron-based additives that, when mixed with certain carrier fluids, such as water, cellulose and/or cellulose derivatives, polyhydric alcohol, polyalkylene glycol, polyvinyl alcohol, starch, dextrin, in solid and/or solvated forms result in improved metalworking and machining of metallic work pieces. Fluids manufactured with boric acid or boron-based additives effectively reduce friction, prevent galling and severe wear problems on cutting and forming tools.

Erdemir, Ali (Naperville, IL); Sykora, Frank (Caledon, ON, CA); Dorbeck, Mark (Brighton, MI)

2010-10-12

301

Human-machine interactions  

DOEpatents

Digital technology utilizing a cognitive model based on human naturalistic decision-making processes, including pattern recognition and episodic memory, can reduce the dependency of human-machine interactions on the abilities of a human user and can enable a machine to more closely emulate human-like responses. Such a cognitive model can enable digital technology to use cognitive capacities fundamental to human-like communication and cooperation to interact with humans.

Forsythe, J. Chris (Sandia Park, NM); Xavier, Patrick G. (Albuquerque, NM); Abbott, Robert G. (Albuquerque, NM); Brannon, Nathan G. (Albuquerque, NM); Bernard, Michael L. (Tijeras, NM); Speed, Ann E. (Albuquerque, NM)

2009-04-28

302

Sealing intersecting vane machines  

DOEpatents

The invention provides a toroidal intersecting vane machine incorporating intersecting rotors to form primary and secondary chambers whose porting configurations minimize friction and maximize efficiency. Specifically, it is an object of the invention to provide a toroidal intersecting vane machine that greatly reduces the frictional losses through intersecting surfaces without the need for external gearing by modifying the width of one or both tracks at the point of intermeshing. The inventions described herein relate to these improvements.

Martin, Jedd N.; Chomyszak, Stephen M.

2005-06-07

303

The Lisp Machine manual  

Microsoft Academic Search

This 471-page, softcover manual describes the programming language and software environment of the Lisp Machine developed at M.I.T.'s Artificial Intelligence Laboratory over the past 8 years. The Lisp Machine is the result of a successful experiment in computer science: a distributed computing system consisting of a network of powerful 32-bit personal computers, implemented with custom hardware and software as complete,

Daniel Weinreb; David Moon

1981-01-01

304

Sealing intersecting vane machines  

DOEpatents

The invention provides a toroidal intersecting vane machine incorporating intersecting rotors to form primary and secondary chambers whose porting configurations minimize friction and maximize efficiency. Specifically, it is an object of the invention to provide a toroidal intersecting vane machine that greatly reduces the frictional losses through intersecting surfaces without the need for external gearing by modifying the width of one or both tracks at the point of intermeshing. The inventions described herein relate to these improvements.

Martin, Jedd N. (Providence, RI); Chomyszak, Stephen M. (Attleboro, MA)

2007-06-05

305

Could a machine think  

SciTech Connect

There are many reasons for saying yes. One of the earliest and deepest reason lay in two important results in computational theory. The first was Church's thesis, which states that every effectively computable function is recursively computable. The second important result was Alan M. Turing's demonstration that any recursively computable function can be computed in finite time by a maximally simple sort of symbol-manipulating machine that has come to be called a universal Turing machine. This machine is guided by a set of recursively applicable rules that are sensitive to the identity, order and arrangement of the elementary symbols it encounters as input. The authors reject the Turing test as a sufficient condition for conscious intelligence. They base their position of the specific behavioral failures of the classical SM machines and on the specific virtues of machines with a more brain-like architecture. These contrasts show that certain computational strategies have vast and decisive advantages over others where typical cognitive tasks are concerned, advantages that are empirically inescapable. Clearly, the brain is making systematic use of these computational advantage. But it need not be the only physical system capable of doing so. Artificial intelligence, in a nonbiological but massively parallel machine, remain a compelling and discernible prospect.

Churchland, P.M.; Churchland, P.S. (Univ. of California, San Diego (USA))

1990-01-01

306

Wave Machine Model  

NSDL National Science Digital Library

This model simulates the wave generating machine created by John Shive at Bell Laboratories and made famous by the Similarities in Wave Behavior film. The machine consists of horizontal cross-bars welded to a central wire spine that is perpendicular to the bars. The spine was constructed so that it can freely twist, allowing the cross-bars to produce wave-like patterns. The simulation allows various pulse shapes to be sent down the machine by selecting a function for the twist of the first rod or by dragging the first rod. The far end of the wave machine can be free or fixed, which changes the nature of the reflected wave. Change the lengths of the bars to simulate the effect of a wave propagating in a non-uniform medium. The original film that introduced Dr. Shive's wave generating machine can be viewed at no cost: Film: Similarities of Wave Behavior (AT&T Archives and History Collection). The Wave Machine model was created using the Easy Java Simulations (EJS) modeling tool. It is distributed as a ready-to-run (compiled) Java archive.

2010-11-07

307

Harvesting Machine Census 1999 & 2001  

E-print Network

1 Harvesting Machine Census 1999 & 2001 231 Corstorphine Road Edinburgh EH12 7AT www.forestry.gov.uk FCTN001 SUMMARY This Technical Note contains information on the 1999 and 2001 harvesting machine machines, converted forwarders, etc., account for the remaining machines. In the 2001 census, 65

308

MACHINE MONITORING USING PROBABILITY THRESHOLDS  

E-print Network

MACHINE MONITORING USING PROBABILITY THRESHOLDS AND SYSTEM OPERATING CHARACTERISTICS Stephen M a discrete-part production machine, with the objective of effectively determining when to shut the machine analysis: a) There is an underlying time interval that characterizes the operation of the machine, most

Pollock, Stephen

309

The Knife Machine. Module 15.  

ERIC Educational Resources Information Center

This module on the knife machine, one in a series dealing with industrial sewing machines, their attachments, and operation, covers one topic: performing special operations on the knife machine (a single needle or multi-needle machine which sews and cuts at the same time). These components are provided: an introduction, directions, an objective,…

South Carolina State Dept. of Education, Columbia. Office of Vocational Education.

310

The Buttonhole Machine. Module 13.  

ERIC Educational Resources Information Center

This module on the bottonhole machine, one in a series dealing with industrial sewing machines, their attachments, and operation, covers two topics: performing special operations on the buttonhole machine (parts and purpose) and performing special operations on the buttonhole machine (gauged buttonholes). For each topic these components are…

South Carolina State Dept. of Education, Columbia. Office of Vocational Education.

311

Recombinations of Busy Beaver Machines  

E-print Network

Many programmers belive that Turing-based machines cannot think. We also believe in this, however it is interesting to note that the most sophisticated machines are not programmed by human beings. We have only discovered them. In this paper, using well-known Busy Beaver and Placid Platypus machines, we generate further very similar, but not exactly the same machines. We have found a recombinated BB_5 machine which can make 70.740.809 steps before halting.

Bátfai, Norbert

2009-01-01

312

Comparison of electrical machine types in hybrid drive trains: Induction machine vs. permanent magnet synchronous machine  

Microsoft Academic Search

The intention of the present paper is to draw a reasonable comparison of two different types of electrical machines for use in a parallel hybrid drive train: the induction machine with cage rotor on the one hand, the permanent magnet synchronous machine on the other hand. Both machine types have been designed for application in a mild hybrid vehicle. By

D. Bucherl; R. Nuscheler; W. Meyer; H.-G. Herzog

2008-01-01

313

The bearingless electrical machine  

NASA Astrophysics Data System (ADS)

Electromagnetic bearings allow the suspension of solids. For rotary applications, the most important physical effect is the force of a magnetic circuit to a high permeable armature, called the MAXWELL force. Contrary to the commonly used MAXWELL bearings, the bearingless electrical machine will take advantage of the reaction force of a conductor carrying a current in a magnetic field. This kind of force, called Lorentz force, generates the torque in direct current, asynchronous and synchronous machines. The magnetic field, which already exists in electrical machines and helps to build up the torque, can also be used for the suspension of the rotor. Besides the normal winding of the stator, a special winding was added, which generates forces for levitation. So a radial bearing, which is integrated directly in the active part of the machine, and the motor use the laminated core simultaneously. The winding was constructed for the levitating forces in a special way so that commercially available standard ac inverters for drives can be used. Besides wholly magnetic suspended machines, there is a wide range of applications for normal drives with ball bearings. Resonances of the rotor, especially critical speeds, can be damped actively.

Bichsel, J.

1992-05-01

314

The Bearingless Electrical Machine  

NASA Technical Reports Server (NTRS)

Electromagnetic bearings allow the suspension of solids. For rotary applications, the most important physical effect is the force of a magnetic circuit to a high permeable armature, called the MAXWELL force. Contrary to the commonly used MAXWELL bearings, the bearingless electrical machine will take advantage of the reaction force of a conductor carrying a current in a magnetic field. This kind of force, called Lorentz force, generates the torque in direct current, asynchronous and synchronous machines. The magnetic field, which already exists in electrical machines and helps to build up the torque, can also be used for the suspension of the rotor. Besides the normal winding of the stator, a special winding was added, which generates forces for levitation. So a radial bearing, which is integrated directly in the active part of the machine, and the motor use the laminated core simultaneously. The winding was constructed for the levitating forces in a special way so that commercially available standard ac inverters for drives can be used. Besides wholly magnetic suspended machines, there is a wide range of applications for normal drives with ball bearings. Resonances of the rotor, especially critical speeds, can be damped actively.

Bichsel, J.

1992-01-01

315

Extreme ultraviolet lithography machine  

DOEpatents

An extreme ultraviolet lithography (EUVL) machine or system for producing integrated circuit (IC) components, such as transistors, formed on a substrate. The EUVL machine utilizes a laser plasma point source directed via an optical arrangement onto a mask or reticle which is reflected by a multiple mirror system onto the substrate or target. The EUVL machine operates in the 10-14 nm wavelength soft x-ray photon. Basically the EUV machine includes an evacuated source chamber, an evacuated main or project chamber interconnected by a transport tube arrangement, wherein a laser beam is directed into a plasma generator which produces an illumination beam which is directed by optics from the source chamber through the connecting tube, into the projection chamber, and onto the reticle or mask, from which a patterned beam is reflected by optics in a projection optics (PO) box mounted in the main or projection chamber onto the substrate. In one embodiment of a EUVL machine, nine optical components are utilized, with four of the optical components located in the PO box. The main or projection chamber includes vibration isolators for the PO box and a vibration isolator mounting for the substrate, with the main or projection chamber being mounted on a support structure and being isolated.

Tichenor, Daniel A. (Castro Valley, CA); Kubiak, Glenn D. (Livermore, CA); Haney, Steven J. (Tracy, CA); Sweeney, Donald W. (San Ramon, CA)

2000-01-01

316

Micro-machined resonator  

DOEpatents

A micro-machined resonator, typically quartz, with upper and lower micro-machinable support members, or covers, having etched wells which may be lined with conductive electrode material, between the support members is a quartz resonator having an energy trapping quartz mesa capacitively coupled to the electrode through a diaphragm; the quartz resonator is supported by either micro-machined cantilever springs or by thin layers extending over the surfaces of the support. If the diaphragm is rigid, clock applications are available, and if the diaphragm is resilient, then transducer applications can be achieved. Either the thin support layers or the conductive electrode material can be integral with the diaphragm. In any event, the covers are bonded to form a hermetic seal and the interior volume may be filled with a gas or may be evacuated. In addition, one or both of the covers may include oscillator and interface circuitry for the resonator.

Godshall, Ned A. (Albuquerque, NM); Koehler, Dale R. (Albuquerque, NM); Liang, Alan Y. (Albuquerque, NM); Smith, Bradley K. (Albuquerque, NM)

1993-01-01

317

Micro-machined resonator  

DOEpatents

A micro-machined resonator, typically quartz, with upper and lower micro-machinable support members, or covers, having etched wells which may be lined with conductive electrode material, between the support members is a quartz resonator having an energy trapping quartz mesa capacitively coupled to the electrode through a diaphragm; the quartz resonator is supported by either micro-machined cantilever springs or by thin layers extending over the surfaces of the support. If the diaphragm is rigid, clock applications are available, and if the diaphragm is resilient, then transducer applications can be achieved. Either the thin support layers or the conductive electrode material can be integral with the diaphragm. In any event, the covers are bonded to form a hermetic seal and the interior volume may be filled with a gas or may be evacuated. In addition, one or both of the covers may include oscillator and interface circuitry for the resonator.

Godshall, N.A.; Koehler, D.R.; Liang, A.Y.; Smith, B.K.

1993-03-30

318

Precision Robotic Assembly Machine  

SciTech Connect

The world's largest laser system is the National Ignition Facility (NIF), located at Lawrence Livermore National Laboratory. NIF's 192 laser beams are amplified to extremely high energy, and then focused onto a tiny target about the size of a BB, containing frozen hydrogen gas. The target must be perfectly machined to incredibly demanding specifications. The Laboratory's scientists and engineers have developed a device called the "Precision Robotic Assembly Machine" for this purpose. Its unique design won a prestigious R&D-100 award from R&D Magazine.

2009-08-14

319

Precision Robotic Assembly Machine  

ScienceCinema

The world's largest laser system is the National Ignition Facility (NIF), located at Lawrence Livermore National Laboratory. NIF's 192 laser beams are amplified to extremely high energy, and then focused onto a tiny target about the size of a BB, containing frozen hydrogen gas. The target must be perfectly machined to incredibly demanding specifications. The Laboratory's scientists and engineers have developed a device called the "Precision Robotic Assembly Machine" for this purpose. Its unique design won a prestigious R&D-100 award from R&D Magazine.

None

2010-09-01

320

Automated fiber pigtailing machine  

DOEpatents

The Automated Fiber Pigtailing Machine (AFPM) aligns and attaches optical fibers to optoelectronic (OE) devices such as laser diodes, photodiodes, and waveguide devices without operator intervention. The so-called pigtailing process is completed with sub-micron accuracies in less than 3 minutes. The AFPM operates unattended for one hour, is modular in design and is compatible with a mass production manufacturing environment. This machine can be used to build components which are used in military aircraft navigation systems, computer systems, communications systems and in the construction of diagnostics and experimental systems. 26 figs.

Strand, O.T.; Lowry, M.E.

1999-01-05

321

Automated fiber pigtailing machine  

DOEpatents

The Automated Fiber Pigtailing Machine (AFPM) aligns and attaches optical fibers to optoelectonic (OE) devices such as laser diodes, photodiodes, and waveguide devices without operator intervention. The so-called pigtailing process is completed with sub-micron accuracies in less than 3 minutes. The AFPM operates unattended for one hour, is modular in design and is compatible with a mass production manufacturing environment. This machine can be used to build components which are used in military aircraft navigation systems, computer systems, communications systems and in the construction of diagnostics and experimental systems.

Strand, Oliver T. (Castro Valley, CA); Lowry, Mark E. (Castro Valley, CA)

1999-01-01

322

The Connection Machine  

SciTech Connect

This book describes what history may judge to be the second stage in the evolution of digital computers. Up to now, all computers have had basically the same architecture: one or a few large memory banks. Challenging that conception, the Connection Machine links together thousands or millions of extremely small processors and memories. From each moment to the next, the programs for this singularly versatile machine can refigure its architecture to suit the natural requirements of problems to be solved. The resulting configurations have already been applied to diverse data-structures required for processes involved with artificial intelligence, cellular physics, database inference, and number crunching computation.

Hillis, W.D.

1985-01-01

323

Intersecting vane machines  

DOEpatents

The invention provides a toroidal intersecting vane machine incorporating intersecting rotors to form primary and secondary chambers whose porting configurations minimize friction and maximize efficiency. Specifically, it is an object of the invention to provide a toroidal intersecting vane machine that greatly reduces the frictional losses through meshing surfaces without the need for external gearing by modifying the function of one or the other of the rotors from that of "fluid moving" to that of "valving" thereby reducing the pressure loads and associated inefficiencies at the interface of the meshing surfaces. The inventions described herein relate to these improvements.

Bailey, H. Sterling; Chomyszak, Stephen M.

2007-01-16

324

Paradigms for machine learning  

NASA Technical Reports Server (NTRS)

Five paradigms are described for machine learning: connectionist (neural network) methods, genetic algorithms and classifier systems, empirical methods for inducing rules and decision trees, analytic learning methods, and case-based approaches. Some dimensions are considered along with these paradigms vary in their approach to learning, and the basic methods are reviewed that are used within each framework, together with open research issues. It is argued that the similarities among the paradigms are more important than their differences, and that future work should attempt to bridge the existing boundaries. Finally, some recent developments in the field of machine learning are discussed, and their impact on both research and applications is examined.

Schlimmer, Jeffrey C.; Langley, Pat

1991-01-01

325

BRASS FOUNDRY MACHINE ROOM USED TO MACHINE CAST BRONZE PIECES ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

BRASS FOUNDRY MACHINE ROOM USED TO MACHINE CAST BRONZE PIECES FOR VALVES AND PREPARE BRONZE VALVE BODIES FOR ASSEMBLY. - Stockham Pipe & Fittings Company, Brass Foundry, 4000 Tenth Avenue North, Birmingham, Jefferson County, AL

326

42. MACHINE SHOP Machine shop area with small parts bins ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

42. MACHINE SHOP Machine shop area with small parts bins on the right and pipe storage racks on the left. Remains of the power drive system are suspended from the ceiling. - Hovden Cannery, 886 Cannery Row, Monterey, Monterey County, CA

327

8. VIEW OF THE MACHINE SHOP. BY 1966, THE MACHINE ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. VIEW OF THE MACHINE SHOP. BY 1966, THE MACHINE SHOP HANDLED PRIMARILY STAINLESS STEEL COMPONENTS, WHICH WERE SENT TO THE MACHINE SHOP TO BE FORMED INTO THEIR FINAL SHAPES. (7/24/70) - Rocky Flats Plant, General Manufacturing, Support, Records-Central Computing, Southern portion of Plant, Golden, Jefferson County, CO

328

Progress in Documentation: Machine Translation and Machine-Aided Translation.  

ERIC Educational Resources Information Center

Discusses the prospects for fully automatic machine translation of good quality. Sections include history and background, operational and experimental machine translation systems of recent years, descriptions of interactive systems and machine-assisted translation, and a general survey of present problems and future possibilities. (VT)

Hutchins, W. J.

1978-01-01

329

Tool allocation and machining conditions optimization for CNC machines  

Microsoft Academic Search

In the literature, there exist many variations of machining economics problem in terms of modelling approaches and solution methodologies. However most of the existing studies focus on the single machining operation which is seldom in practice. On the other hand, tool management approaches at the system level fail to relate the tooling issues to the machining conditions, and ignore the

M. Selim Akturk; Selcuk Avci

1996-01-01

330

Machine Pacing and Shiftwork  

Microsoft Academic Search

Machine-paced work and shiftwork are highly prevalent working conditions commonly believed to have adverse individual and organizational consequences. This article examines the empirical evidence for such effects, and acknowledges the conceptual and methodological problems which have clearly plagued pacing and shiftwork researchers. The literature on pacing while suggestive of overall health and performance effects indicates that the magnitude of such

Joseph J Hurrell Jr; Michael J Colligan

1987-01-01

331

The Variable Machine  

NSDL National Science Digital Library

This math lesson provides an introduction to the use of variables, and develops learners' algebraic thinking. Learners create "variable machines" out of paper to discover the "value" of words like their first and last names. Learners explore which words have even or odd values and which words have the largest value. This lesson guide includes questions for learners, extensions, and reflection questions.

2012-06-01

332

Cybernetic anthropomorphic machine systems  

NASA Technical Reports Server (NTRS)

Functional descriptions are provided for a number of cybernetic man machine systems that augment the capacity of normal human beings in the areas of strength, reach or physical size, and environmental interaction, and that are also applicable to aiding the neurologically handicapped. Teleoperators, computer control, exoskeletal devices, quadruped vehicles, space maintenance systems, and communications equipment are considered.

Gray, W. E.

1974-01-01

333

Neutron irradiation therapy machine  

Microsoft Academic Search

In a neutron irradiation therapy machine for treating patients with a beam of high energy neutrons, a gantry is provided which supports a non-superconducting cyclotron proton accelerator and target for generating a neutron beam and which permits rotation of the accelerator and neutron beam around an axis of revolution coaxial with a patient treatment zone. A counter-weight is carried from

Nunan

1978-01-01

334

The Connection Machine  

Microsoft Academic Search

This book describes what history may judge to be the second stage in the evolution of digital computers. Up to now, all computers have had basically the same architecture: one or a few large memory banks. Challenging that conception, the Connection Machine links together thousands or millions of extremely small processors and memories. From each moment to the next, the

W. Daniel Hillis

1985-01-01

335

Machine Aids to Translation.  

ERIC Educational Resources Information Center

Describes the TEAM Program System of the Siemens Language Services Department, particularly the main features of its terminology data bank. Discusses criteria to which stored terminology must conform and methods of data bank utilization. Concludes by summarizing the consequences that machine-aided translation development has had for the…

Brinkmann, Karl-Heinz

1981-01-01

336

The Answer Machine.  

ERIC Educational Resources Information Center

Discusses information retrieval systems and the need to have them adapt to user needs, integrate information in any format, reveal patterns and trends in information, and answer questions. Topics include statistics and probability; natural language processing; intelligent agents; concept mapping; machine-aided indexing; text mining; filtering;…

Feldman, Susan

2000-01-01

337

Double Function Machine  

NSDL National Science Digital Library

This Flash applet allows the user to explore the concept of a function using an input-output machine with two operations and options to set and hide or reveal all operations and numbers. A notepad is available for recording inputs and outputs, and a loop function takes the current output as the next input.

Dan Bunker

2010-01-01

338

Laser machining of explosives  

DOEpatents

The invention consists of a method for machining (cutting, drilling, sculpting) of explosives (e.g., TNT, TATB, PETN, RDX, etc.). By using pulses of a duration in the range of 5 femtoseconds to 50 picoseconds, extremely precise and rapid machining can be achieved with essentially no heat or shock affected zone. In this method, material is removed by a nonthermal mechanism. A combination of multiphoton and collisional ionization creates a critical density plasma in a time scale much shorter than electron kinetic energy is transferred to the lattice. The resulting plasma is far from thermal equilibrium. The material is in essence converted from its initial solid-state directly into a fully ionized plasma on a time scale too short for thermal equilibrium to be established with the lattice. As a result, there is negligible heat conduction beyond the region removed resulting in negligible thermal stress or shock to the material beyond a few microns from the laser machined surface. Hydrodynamic expansion of the plasma eliminates the need for any ancillary techniques to remove material and produces extremely high quality machined surfaces. There is no detonation or deflagration of the explosive in the process and the material which is removed is rendered inert.

Perry, Michael D. (Livermore, CA); Stuart, Brent C. (Fremont, CA); Banks, Paul S. (Livermore, CA); Myers, Booth R. (Livermore, CA); Sefcik, Joseph A. (Tracy, CA)

2000-01-01

339

Fuzzy support vector machines  

Microsoft Academic Search

A support vector machine (SVM) learns the decision surface from two distinct classes of the input points. In many applications, each input point may not be fully assigned to one of these two classes. In this paper, we apply a fuzzy membership to each input point and reformulate the SVMs such that different input points can make different contributions to

Chun-Fu Lin; Sheng-De Wang

2002-01-01

340

Machines That Teach.  

ERIC Educational Resources Information Center

This paper reviews efforts which have been made to improve the effectiveness of teaching through the development of principles of programed teaching and the construction of teaching machines, concluding that a combination of computer technology and programed teaching principles offers an efficient approach to improving teaching. Three different…

Sniecinski, Jozef

341

Working with Simple Machines  

ERIC Educational Resources Information Center

A set of examples is provided that illustrate the use of work as applied to simple machines. The ramp, pulley, lever and hydraulic press are common experiences in the life of a student, and their theoretical analysis therefore makes the abstract concept of work more real. The mechanical advantage of each of these systems is also discussed so that…

Norbury, John W.

2006-01-01

342

Support vector machines  

NASA Technical Reports Server (NTRS)

Support Vector Machines (SVMs) are a type of supervised learning algorith,, other examples of which are Artificial Neural Networks (ANNs), Decision Trees, and Naive Bayesian Classifiers. Supervised learning algorithms are used to classify objects labled by a 'supervisor' - typically a human 'expert.'.

Garay, Michael J.; Mazzoni, Dominic; Davies, Roger; Wagstaff, Kiri

2004-01-01

343

Electropulse chemical machining  

Microsoft Academic Search

Electropulse Chemical Machining, a new technique in chemical milling was applied to the photoforming of molybdenum. Direct current was applied in short pulses at current densities of thousands of amperes per square foot with little thermal degradation of resists or workpieces. Etch rates an order of magnitude faster than those of existing methods, with a corresponding improvement in surface finish

T. A. Allen; S. D. Rospopo

1984-01-01

344

Electrical Discharge Machining.  

ERIC Educational Resources Information Center

The manual is for use by students learning electrical discharge machining (EDM). It consists of eight units divided into several lessons, each designed to meet one of the stated objectives for the unit. The units deal with: introduction to and advantages of EDM, the EDM process, basic components of EDM, reaction between forming tool and workpiece,…

Montgomery, C. M.

345

Dynamic characterization of machining systems  

Microsoft Academic Search

In the working space model of machining, an experimental procedure is implemented to determine the elastic behaviour of the\\u000a machining system. In this paper, a dynamic characterization and vibration analysis has long been used for the detection and\\u000a identification of the machine tool condition. The natural frequencies of the lathe machining system are required (Ernault\\u000a HN400—France) according to three different

Miron Zapciu; Jean-Yves K’nevez; Alain Gérard; Olivier Cahuc; Claudiu Florinel Bisu

346

Move it! With Simple Machines  

NSDL National Science Digital Library

In this Science NetLinks lesson, students will start by discussing a couple of the simple machines and what the purpose of them might be. Then, after reading a short page on each simple machine, they will discuss how the simple machines function. They will explore this briefly in a hands-on fashion and lead into the discussion and realization that these tools are the base for almost any machine or more complex tool that we use.

Science Netlinks

2003-01-21

347

Lightning Protection for Rotating Machines  

Microsoft Academic Search

The high monetary value and low insulation levels of rotating machines make it necessary to employ special protection. A rotating machine can be conceived as a transmission line with distributed constants, the essential difference being that the machine winding is wound back on itself in the form of turns, which may permit high voltage across the turn-to-turn insulation. The installation

G. D. McCann; E. Beck; L. A. Finzi

1944-01-01

348

The Chainstitch Machine. Module 18.  

ERIC Educational Resources Information Center

This module on the chainstitch machine, one in a series dealing with industrial sewing machines, their attachments, and operation, covers one topic: performing special operations on the chainstitch machine. These components are provided: an introduction, directions, an objective, learning activities, student information, a student self-check, and…

South Carolina State Dept. of Education, Columbia. Office of Vocational Education.

349

Hydraulic Fatigue-Testing Machine  

NASA Technical Reports Server (NTRS)

Fatigue-testing machine applies fluctuating tension to number of specimens at same time. When sample breaks, machine continues to test remaining specimens. Series of tensile tests needed to determine fatigue properties of materials performed more rapidly than in conventional fatigue-testing machine.

Hodo, James D.; Moore, Dennis R.; Morris, Thomas F.; Tiller, Newton G.

1987-01-01

350

Interferometer systems in machine industry  

NASA Astrophysics Data System (ADS)

In the report the arrangements of laser interferometers for machine history are presented; the laser interferometer LSP30 for investigation of geometry of machine tools, the setup for inspection of ball screw and laser liner for CNC machine. Outstanding feature of the interferometers is the stabilization system of laser frequency using surface stabilized ferroelectric liquid cells (SSFLC).

Rzepka, Janusz; Pienkowski, Janusz; Sambor, Slawomir; Budzyn, Grzegorz

2003-10-01

351

Machine Shop Fundamentals: Part I.  

ERIC Educational Resources Information Center

These instructional materials were developed and designed for secondary and adult limited English proficient students enrolled in machine tool technology courses. Part 1 includes 24 lessons covering introduction, safety and shop rules, basic machine tools, basic machine operations, measurement, basic blueprint reading, layout, and bench tools.…

Kelly, Michael G.; And Others

352

Support Vector Machine(SVM)  

E-print Network

Support Vector Machine(SVM) Jinlong Wu Outline Some Classification Problems From The Real World Techniques Support Vector Machine(SVM) Jinlong Wu Department of Scientific and Engineering Computing, School of Mathematical Scineces, PKU 2007. 6.1 1 / 37 #12;Support Vector Machine(SVM) Jinlong Wu Outline Some

Li, Tiejun

353

Simple Machines/Forces and Motion  

NSDL National Science Digital Library

These are a list of links and activities about simple machines and forces and motion. To get the username and password for Pioneer Library talk to your local librarian. SIMPLE MACHINES ACTIVITIES Simple Machines (BrainPopJr)- This has a video about simple machines and activities as well. For some interactive activities about simple machines I really like these sites Simple Machines and Compound Machines (EdHeads), Simple Machines (MSI), and Learning Games for Kids. When you combine two or more simple machines you get compound machines, to look more into those go to The Compound Machine (EdHeads). To ...

Miss B

2011-11-04

354

A Boltzmann machine for the organization of intelligent machines  

NASA Technical Reports Server (NTRS)

In the present technological society, there is a major need to build machines that would execute intelligent tasks operating in uncertain environments with minimum interaction with a human operator. Although some designers have built smart robots, utilizing heuristic ideas, there is no systematic approach to design such machines in an engineering manner. Recently, cross-disciplinary research from the fields of computers, systems AI and information theory has served to set the foundations of the emerging area of the design of intelligent machines. Since 1977 Saridis has been developing an approach, defined as Hierarchical Intelligent Control, designed to organize, coordinate and execute anthropomorphic tasks by a machine with minimum interaction with a human operator. This approach utilizes analytical (probabilistic) models to describe and control the various functions of the intelligent machine structured by the intuitively defined principle of Increasing Precision with Decreasing Intelligence (IPDI) (Saridis 1979). This principle, even though resembles the managerial structure of organizational systems (Levis 1988), has been derived on an analytic basis by Saridis (1988). The purpose is to derive analytically a Boltzmann machine suitable for optimal connection of nodes in a neural net (Fahlman, Hinton, Sejnowski, 1985). Then this machine will serve to search for the optimal design of the organization level of an intelligent machine. In order to accomplish this, some mathematical theory of the intelligent machines will be first outlined. Then some definitions of the variables associated with the principle, like machine intelligence, machine knowledge, and precision will be made (Saridis, Valavanis 1988). Then a procedure to establish the Boltzmann machine on an analytic basis will be presented and illustrated by an example in designing the organization level of an Intelligent Machine. A new search technique, the Modified Genetic Algorithm, is presented and proved to converge to the minimum of a cost function. Finally, simulations will show the effectiveness of a variety of search techniques for the intelligent machine.

Moed, Michael C.; Saridis, George N.

1989-01-01

355

Study on a new kind of combined machining technology of ultrasonic machining and electrical discharge machining  

Microsoft Academic Search

An analysis on the mechanisms of ultrasonic machining and electrical discharge machining has been carried out, and a technology, which combines the advantages of both of them, has been proposed in this paper. It can be used to machine all conductive hard and brittle materials with high efficiency and surface integrity. The mechanism of this combined technology has been studied

Jia Zhixin; Zhang Jianhua; Ai Xing

1997-01-01

356

Some Results of Fuzzy Turing Machines  

Microsoft Academic Search

In this paper we study the variants of fuzzy Turing machines and universal fuzzy Turing machine. First we give several equivalent formulations of fuzzy Turing machines which correspond to fuzzy deterministic Turing machines (FDTMs), fuzzy nondeterministic Turing machines (FNTMs) and multitape fuzzy Turing machines. Then the notions of fuzzy recursively enumerable languages and fuzzy recursive languages are defined in terms

Yongming Li

2006-01-01

357

Ecosystems, Organisms, and Machines  

NSDL National Science Digital Library

This peer reviewed article from Bioscience is about is the concept, and the term, "self-organization." The history of this term, originally introduced by Immanuel Kant to characterize the unique properties of living organisms, is inseparable from the history of biology. Only in the second half of the 20th century does it begin to acquire the promise of a physicalistic understanding. This it does with two critical transformations in the meaning of the term: first, with the advent of cybernetics and its dissolution of the boundary between organisms and machines, and second, with the mathematical triumphs of nonlinear dynamical systems theory and accompanying claims to having dissolved the boundary between organisms and such physical phenomena as thunderstorms. How do these transformations affect the applicability of self-organization to the ecosystem--that provocatively hybrid entity that is part organism, part machine, and perhaps even part thunderstorm?

EVELYN FOX KELLER (; )

2005-12-01

358

Smart Machine Protection System  

SciTech Connect

A Machine Protection System implemented on the SLC automatically controls the beam repetition rates in the accelerator so that radiation or temperature faults slow the repetition rate to bring the fault within tolerance without shutting down the machine. This process allows the accelerator to aid in the fault diagnostic process, and the protection system automatically restores the beams back to normal rates when the fault is diagnosed and corrected. The user interface includes facilities to monitor the performance of the system, and track rate limits, faults, and recoveries. There is an edit facility to define the devices to be included in the protection system, along with their set points, limits, and trip points. This set point and limit data is downloaded into the CAMAC modules, and the configuration data is compiled into a logical decision tree for the 68030 processor. 3 figs.

Clark, S.; Nelson, D.; Grillo, A.; Spencer, N.; Hutchinson, D.; Olsen, J.; Millsom, D.; White, G.; Gromme, T.; Allison, S.; Underwood, K.; Zelazny, M.; Kang, H.

1991-11-01

359

CNC electrical discharge machining centers  

SciTech Connect

Computer numerical control (CNC) electrical discharge machining (EDM) centers were investigated to evaluate the application and cost effectiveness of establishing this capability at Allied-Signal Inc., Kansas City Division (KCD). In line with this investigation, metal samples were designed, prepared, and machined on an existing 15-year-old EDM machine and on two current technology CNC EDM machining centers at outside vendors. The results were recorded and evaluated. The study revealed that CNC EDM centers are a capability that should be established at KCD. From the information gained, a machine specification was written and a shop was purchased and installed in the Engineering Shop. The older machine was exchanged for a new model. Additional machines were installed in the Tool Design and Fabrication and Precision Microfinishing departments. The Engineering Shop machine will be principally used for the following purposes: producing deep cavities in small corner radii, machining simulated casting models, machining difficult-to-machine materials, and polishing difficult-to-hand polish mold cavities. 2 refs., 18 figs., 3 tabs.

Jaggars, S.R.

1991-10-01

360

The Variable Machine  

NSDL National Science Digital Library

This lesson from Illuminations provides an introduction to the use of variables, and develops students' algebraic thinking. Students create variable machines to discover the value of words by assigning each letter of the alphabet a unique number value. Learning objectives, a materials list, a pdf file of the student worksheet, an instructional plan, questions for the students, assessment options, extensions, and teacher reflections are provided.

2008-01-01

361

Swinging Atwood's Machine  

NASA Astrophysics Data System (ADS)

We examine the motion of an Atwood's Machine in which one of the masses is allowed to swing in a plane. Computer studies reveal a rich variety of trajectories. The orbits are classified (bounded, periodic, singular, and terminating), and formulas for the critical mass ratios are developed. Perturbative techniques yield good approximations to the computer-generated trajectories. The model constitutes a simple example of a nonlinear dynamical system with two degrees of freedom.

Tufillaro, Nicholas B.; Abbott, Tyler A.; Griffiths, David J.

1984-10-01

362

Copying Machine Improvement  

NASA Technical Reports Server (NTRS)

Manufacturer of the Model 2210 copying machine was looking for a plastic valve bushing material that could be produced by a low-cost injection molding process to replace the unsuitable valve bushing they were using. NERAC conducted a computer search of the NASA database and was able to supply Nashua Corporation with several technical reports in their area of interest. Information aided the company's development of a urethane valve bushing which solved the problem and created a dramatic reduction in unit cost.

1981-01-01

363

Dynamic monocular machine vision  

Microsoft Academic Search

A new approach to real-time machine vision in dynamic scenes is presented based on special hardware and methods for feature extraction and information processing. Using integral spatio-temporal models, it by-passes the nonunique inversion of the perspective projection by applying recursive least squares filtering. By prediction error feedback methods similar to those used in modern control theory, all spatial state variables

Ernst Dieter Dickmanns; Volker Graefe

1988-01-01

364

Bayes Point Machines  

Microsoft Academic Search

Kernel-classifiers comprise a powerful class of non-linear decision functions for binary classification. The support vector machine is an example of a learning algorithm for kernel classifiers that singles out the consistent classifier with the largest margin, i.e. minimal real-valued output on the training sample, within the set of consistent hypotheses, the so-called measure and leads to a steady decrease in

Ralf Herbrich; Thore Graepel; Colin Campbell

2001-01-01

365

Machine Translation from Text  

NASA Astrophysics Data System (ADS)

Machine translation (MT) from text, the topic of this chapter, is perhaps the heart of the GALE project. Beyond being a well defined application that stands on its own, MT from text is the link between the automatic speech recognition component and the distillation component. The focus of MT in GALE is on translating from Arabic or Chinese to English. The three languages represent a wide range of linguistic diversity and make the GALE MT task rather challenging and exciting.

Habash, Nizar; Olive, Joseph; Christianson, Caitlin; McCary, John

366

Simple Machine Science Centers  

NSDL National Science Digital Library

One solution to the common challenge of teaching physical science for teachers who are not confident with the subject matter or comfortable with the material is inquiry based science centers. Science centers can engage students; accommodate different learning styles and individual interests; help students become independent and confident learners; and encourage social skills among students. One third-grade teacher worked with students as they completed activities at learning centers during a week-long unit on simple machines.

Debby Chessin

2007-02-01

367

Development of reconfigurable machines  

Microsoft Academic Search

This paper summarizes our survey on the development of reconfigurable machines (RMs). The goals of this survey were to (i)\\u000a clarify the needs and drivers to develop the RMs, (ii) define the academic and practical issues involved in the development\\u000a of RMs, (iii) learn the state of the art of the R&D on design methodologies of the RMs, and (iv)

Z. M. Bi; Sherman Y. T. Lang; M. Verner; P. Orban

2008-01-01

368

Superconducting and conventional machines  

NASA Astrophysics Data System (ADS)

A general comparison is made between conventional and superconducting machines using simple semi-quantitative arguments. A basic conventional machine with sinusoidal currents round rotor and stator is analysed analytically and expressions for the power per unit volume found. Typically about 50 MW per cubic metre of rotor can be obtained and the ratio of power to loss is approximatelythe square of the ratio of the diameter to the skin depth of copper. For a superconducting rotor the power depends on BJc which for YBCO is a maximum at 2 T. If this field could be achieved by the stator a superconducting rotor could be several orders of magnitude smaller than a conventional one. However this is very difficult to achieve. At 50 Hz AC losses are a major problem. Hysteresis losses depend on the ratio of the conductor thickness to the rotor radius so striating the conductor is desirable but low coupling losses requires a twist pitch significantly smaller than the penetration depth. The maximum power is proportional to the product of the rotor and stator currents and the main advantage of superconductors is their very high current density. Therefore the ultimate goal is to have both superconducting, but AC losses in the stator make this difficult. However replacing just the rotor conductors in a synchronous machine gives significant reductions in size and weight for a given power by increasing the electric loading.

Campbell, A. M.

2014-12-01

369

15. Interior, Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

15. Interior, Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific Railroad Carlin Shops, view to northeast (90mm lens). The arched cutouts in the bottom chords of the roof trusses were necessary to provide clearance for the smokestacks of steam locomotives, and also mark the location of the former inspection pit in the floor (now filled in and covered by a new concrete floor). - Southern Pacific Railroad, Carlin Shops, Roundhouse Machine Shop Extension, Foot of Sixth Street, Carlin, Elko County, NV

370

A high speed machining algorithm for CNC machine tools  

Microsoft Academic Search

This paper introduces a high speed machining algorithm based on a look-ahead interpolation technique for the machining of 3D surface obtained by a CAD\\/CAM system. Generally, specification of CNC system for high speed machining requires an additional hardware and it burdens end users with additional cost. The purpose of this research is to develop the low cost CNC controller having

Guk-Chan Han; Dong-II Kim; Hyo-Gyu Kim; Kibeohn Nam; Byeong-Kap Choi; Sung-Kwun Kim

1999-01-01

371

Basics of Machine Learning by Support Vector Machines  

Microsoft Academic Search

Here, we talk about the (machine) learning from empirical data (i.e., examples, samples, measurements, records, patterns or observations) by applying support vector machines (SVMs) a.k.a. kernel machines 1. The basic aim of this chapter is to give, as far as possible, a condensed (but systematic) presentation of a novel learning paradigm embodied in SVMs. Our focus Will be on the

V. Kecman

372

Formal modeling of virtual machines  

NASA Technical Reports Server (NTRS)

Systematic software design can be based on the development of a 'hierarchy of virtual machines', each representing a 'level of abstraction' of the design process. The reported investigation presents the concept of 'data space' as a formal model for virtual machines. The presented model of a data space combines the notions of data type and mathematical machine to express the close interaction between data and control structures which takes place in a virtual machine. One of the main objectives of the investigation is to show that control-independent data type implementation is only of limited usefulness as an isolated tool of program development, and that the representation of data is generally dictated by the control context of a virtual machine. As a second objective, a better understanding is to be developed of virtual machine state structures than was heretofore provided by the view of the state space as a Cartesian product.

Cremers, A. B.; Hibbard, T. N.

1978-01-01

373

Will machines ever think  

NASA Technical Reports Server (NTRS)

Artificial Intelligence research has come under fire for failing to fulfill its promises. A growing number of AI researchers are reexamining the bases of AI research and are challenging the assumption that intelligent behavior can be fully explained as manipulation of symbols by algorithms. Three recent books -- Mind over Machine (H. Dreyfus and S. Dreyfus), Understanding Computers and Cognition (T. Winograd and F. Flores), and Brains, Behavior, and Robots (J. Albus) -- explore alternatives and open the door to new architectures that may be able to learn skills.

Denning, P. J.

1986-01-01

374

The Intimate Machine  

NSDL National Science Digital Library

This episode of the PBS television show Scientific American Frontiers, entitled "The Intimate Machine," aired on October 22, 2002. The show is divided into four segments. Interactive, animated computer characters created at the MIT Media Lab are the focus of the first part. The second shows a virtual dog that, just like a real pet, can be trained. Advanced monitoring devices that recognize human emotions are examined in the third segment, while the final part demonstrates a furry robot that emulates human emotions. In addition to being able to view the hour-long episode in streaming video on this site, users can also browse certain Web features.

2002-01-01

375

Linear Function Machine  

NSDL National Science Digital Library

In this activity, students plug values into a function to see what the output is for that function. Then based on that information, they have to guess the coefficient and constant for a linear function. This activity allows students to explore linear functions and what input values are useful to figuring out the linear function performed by the function machine. This activity includes supplemental materials, including background information about the topics covered, a description of how to use the application, and exploration questions for use with the java applet.

2010-01-01

376

NASA: Machine Learning Systems  

NSDL National Science Digital Library

The Machine Learning Systems (MLS) Group at NASA's Jet Propulsion Laboratory conducts basic and applied research with a focus on finding "software solutions to hard problems requiring data mining, knowledge discovery, pattern recognition, and automated classification and clustering." In particular, they are building systems based on learning algorithms to be applied in the analysis of scientific data generated by NASA and JPL instruments and to develop technologies relevant for adaptive systems and autonomous spacecraft. Projects on bioinformatics, multi-angle imaging, and data transmission are described here. Several research papers are also available to download.

377

Tool Condition Monitoring in Machining  

Microsoft Academic Search

Condition monitoring and diagnosis systems which are capable of identifying machining system defects and their location are\\u000a essential for unmanned machining. Unattended (or minimally manned) machining would result in increased capital equipment utilization,\\u000a thus substantially reducing manufacturing costs. A review of tool monitoring systems and techniques and their components is\\u000a presented. The proposed algorithm for MPC fuzzy neural networks is

Mo A. Elbestawi; Mihaela Dumitrescu; Eu-Gene Ng

378

Turing Automata and Graph Machines  

E-print Network

Indexed monoidal algebras are introduced as an equivalent structure for self-dual compact closed categories, and a coherence theorem is proved for the category of such algebras. Turing automata and Turing graph machines are defined by generalizing the classical Turing machine concept, so that the collection of such machines becomes an indexed monoidal algebra. On the analogy of the von Neumann data-flow computer architecture, Turing graph machines are proposed as potentially reversible low-level universal computational devices, and a truly reversible molecular size hardware model is presented as an example.

Bartha, Miklós

2010-01-01

379

Internet Archive Wayback Machine  

NSDL National Science Digital Library

The Internet Archive is the "parent" site for two sites previously reviewed in the Scout Report, Election 2000 (see the July 13, 2001 Scout Report) and September11.archive.org (see the October 19, 2001 Scout Report). The Archive has been cataloging Webpages since its inception in 1996, and for their fifth anniversary has opened the archive to the public by launching their "Wayback Machine." To operate the "Machine," users type a URL into the search box, which will call up dated, archived pages of the site. The Internet Archive holds ten billion Webpages, making it the largest known database. Since announcing public access to the overall database, the site has experienced a great deal of traffic. They are in the process of adding servers, but users should be warned that, in the meantime, access may be tricky. The Internet Archive is a nonprofit, which has received funding from a number of sources including the Library of Congress and the National Science Foundation.

380

Unsteady processes in machines.  

PubMed

Couplings in machines and mechanisms always have play and friction. While under loading, stick-slip phenomena and impact events can take place. Such processes are modeled as multibody systems whose structure is time variant or unsteady. The time-variant number of degrees of freedom is due to stick-slip contacts. The coupling characteristics become unsteady, for instance there exist jumps in the loads, if impacts occur. For establishing a uniform theory for such phenomena we use a Lagrangian approach connecting the additional constraint equations and the equations of motion by Lagrange multipliers, which are proportional to the constraint forces. Stick-slip and impact events are evaluated by indicator functions leading to special numerical algorithms for the search of switching points. Contact problems are formulated as a complementarity problem which can be solved by efficient algorithms. The theory is applied to rattling in gears, impact drilling machines, turbine blade dampers, and a woodpecker toy. In some of these applications, chaos as a result of bifurcations is possible, which results from variations in the parameters. (c) 1994 American Institute of Physics. PMID:12780146

Pfeiffer, Friedrich

1994-12-01

381

Smart Test Machines  

NASA Technical Reports Server (NTRS)

Vern Wedeven, president of Wedeven Associates, developed the WAM4, a computer-aided "smart" test machine for simulating stress on equipment, based on his bearing lubrication expertise gained while working for Lewis Research Center. During his NASA years from the 1970s into the early 1980s, Wedeven initiated an "Interdisciplinary Collaboration in Tribology," an effort that involved NASA, six universities, and several university professors. The NASA-sponsored work provided foundation for Wedeven in 1983 to form his own company. Several versions of the smart test machine, the WAM1, WAM2, and WAM3, have proceeded the current version, WAM4. This computer-controlled device can provide detailed glimpses at gear and bearing points of contact. WAM4 can yield a three-dimensional view of machinery as an operator adds "what-if" thermal and lubrication conditions, contact stress, and surface motion. Along with NASA, a number of firms, including Pratt & Whitney, Caterpillar Tractor, Exxon, and Chevron have approached Wedeven for help on resolving lubrication problems.

1997-01-01

382

Positioning cloud computing in machine to machine business models  

Microsoft Academic Search

The concept and implementation of cloud computing have attracted more and more attention from industry and research community. In this paper, we explore how the industry moves beyond the buzzword of cloud computing and put it into the actual business benefits. Machine to machine (M2M) is selected as the field of implementation as it is hailed as the next big

Arkav Juliandri; Meis Musida; Supriyadi

2012-01-01

383

Universal Developer Platform for MachinePlatform for Machine  

E-print Network

component manufacturers: Get non-embedded software development expertise Attach your product to systems systems etc. June 24-26, 2008 ETH Zurich development, control etc.) Platforms make product development1 Universal Developer Platform for MachinePlatform for Machine Control Applications Hansjoerg

384

Micro-hole machining of carbide by electric discharge machining  

Microsoft Academic Search

This paper describes the characteristics of the micro-hole of carbide by electric discharge machining with a copper tool electrode. Electric discharge machining (EDM) is a thermal process that utilizes a spark discharge to melt a conductive material, the tool electrode being almost non-unloaded, because there is no direct contact between the tool electrode and the workpiece. Therefore, the process works

B. H. Yan; F. Y. Huang; H. M. Chow; J. Y. Tsai

1999-01-01

385

Computational Complexity of Probabilistic Turing Machines  

Microsoft Academic Search

Probabilistic Turing machines are Turing machines with the ability to flip coins in order to make random decisions. We allow probabilistic Turing machines small but nonzero error probability in computing number-theoretic functions. An example is given of a function computable more quickly by probabilistic Turing machines than by deterministic Turing machines. It is shown how probabilistic linear-bounded automata can simulate

John T. Gill III

1974-01-01

386

Design of a linear switched reluctance machine  

Microsoft Academic Search

A standard design procedure for a single-sided and longitudinal flux-based linear switched reluctance machine is developed in this paper. The proposed design procedure utilizes the rotating switched reluctance machine design by converting the specifications of the linear machine into the equivalent rotary machine. The machine design is carried out in the rotary domain, which is then transformed back into the

Byeong-Seok Lee; Han-Kyung Bae; Praveen Vijayraghavan; R. Krishnan

2000-01-01

387

Design of a linear switched reluctance machine  

Microsoft Academic Search

A standard design procedure for a single sided and longitudinal flux based linear switched reluctance machine is developed in this paper. The proposed design procedure utilises the rotating switched reluctance machine design by converting the specifications of the linear machine in to the equivalent rotary machine. The machine design is carried out in the rotary domain which is then transformed

Byeong-Seok Lee; Han-Kyung Bae; Praveen Vijayraghavan; R. Krishnan

1999-01-01

388

Machine performance assessment and enhancement for a hexapod machine  

SciTech Connect

The focus of this study is to develop a sensor fused process modeling and control methodology to model, assess, and then enhance the performance of a hexapod machine for precision product realization. Deterministic modeling technique was used to derive models for machine performance assessment and enhancement. Sensor fusion methodology was adopted to identify the parameters of the derived models. Empirical models and computational algorithms were also derived and implemented to model, assess, and then enhance the machine performance. The developed sensor fusion algorithms can be implemented on a PC-based open architecture controller to receive information from various sensors, assess the status of the process, determine the proper action, and deliver the command to actuators for task execution. This will enhance a hexapod machine`s capability to produce workpieces within the imposed dimensional tolerances.

Mou, J.I. [Arizona State Univ., Tempe, AZ (United States); King, C. [Sandia National Labs., Livermore, CA (United States). Integrated Manufacturing Systems Center

1998-03-19

389

Providing machine tractable dictionary tools  

Microsoft Academic Search

Machine readable dictionaries (Mrds) contain knowledge about language and the world essential for tasks in natural language processing (Nlp). However, this knowledge, collected and recorded by lexicographers for human readers, is not presented in a manner for Mrds to be used directly for Nlp tasks. What is badly needed are machine tractable dictionaries (Mtds): Mrds transformed into a format usable

Yorick Wilks; Dan Fass; Cheng-ming Guo; James E. Mcdonald; Tony Plate; Brian M. Slator

1990-01-01

390

Autonomous Navigation for Forest Machines  

E-print Network

Inertial navigation system (INS) ..............................................................19 WheelAutonomous Navigation for Forest Machines a Pre-Study by Thomas Hellström Department of Computing Science Umeå University Umeå, Sweden 2002-10-18 #12;Autonomous Navigation for Forest Machines ­ a Pre

Hellström, Thomas

391

Machine Learning and Software Engineering  

Microsoft Academic Search

Machine learning deals with the issue of how to build programs that improve their performance at some task through experience. Machine learning algorithms have proven to be of great practical value in a variety of application domains. They are particularly useful for (a) poorly understood problem domains where little knowledge exists for the humans to develop effective algorithms; (b) domains

Du Zhang; Jeffrey J. P. Tsai

2003-01-01

392

Anaesthesia machine: checklist, hazards, scavenging.  

PubMed

From a simple pneumatic device of the early 20(th) century, the anaesthesia machine has evolved to incorporate various mechanical, electrical and electronic components to be more appropriately called anaesthesia workstation. Modern machines have overcome many drawbacks associated with the older machines. However, addition of several mechanical, electronic and electric components has contributed to recurrence of some of the older problems such as leak or obstruction attributable to newer gadgets and development of newer problems. No single checklist can satisfactorily test the integrity and safety of all existing anaesthesia machines due to their complex nature as well as variations in design among manufacturers. Human factors have contributed to greater complications than machine faults. Therefore, better understanding of the basics of anaesthesia machine and checking each component of the machine for proper functioning prior to use is essential to minimise these hazards. Clear documentation of regular and appropriate servicing of the anaesthesia machine, its components and their satisfactory functioning following servicing and repair is also equally important. Trace anaesthetic gases polluting the theatre atmosphere can have several adverse effects on the health of theatre personnel. Therefore, safe disposal of these gases away from the workplace with efficiently functioning scavenging system is necessary. Other ways of minimising atmospheric pollution such as gas delivery equipment with negligible leaks, low flow anaesthesia, minimal leak around the airway equipment (facemask, tracheal tube, laryngeal mask airway, etc.) more than 15 air changes/hour and total intravenous anaesthesia should also be considered. PMID:24249887

Goneppanavar, Umesh; Prabhu, Manjunath

2013-09-01

393

Cleaning of Free Machining Brass  

Microsoft Academic Search

We have investigated four brightening treatments proposed by two cleaning vendors for cleaning free machining brass. The experimental results showed that none of the proposed brightening treatments passed the swipe test. Thus, we maintain the recommendation of not using the brightening process in the cleaning of free machining brass for NIF application.

Shen

2005-01-01

394

Materialization of Universal Turing Machines  

E-print Network

Forum Paderborn, Germany #12;Contents Alan Turing's relation to Germany Turing Machines Hasenjaeger was -- unknowingly -- Alan Turing's one-man counterpart for the security of the ENIGMA on the German side #12;AlanMaterialization of Universal Turing Machines Rainer Glaschick supporting Heinz-Nixdorf Museums

395

Evolutionary programming of CNC machines  

Microsoft Academic Search

The paper proposes a new concept for programming of CNC machines. The concept based on genetic algorithms assures evolutionary generation and optimization of NC programs on the basis of CAD models of manufacturing environment. The structure, undergoing simulated evolution, is the population of NC programs. The NC programs control the machine which performs simple elementary motions. During the evolution the

M. Kovacic; M. Brezocnik; I. Pahole; J. Balic; B. Kecelj

2005-01-01

396

The Machine Intelligence Hex Project  

ERIC Educational Resources Information Center

Hex is a challenging strategy board game for two players. To enhance students' progress in acquiring understanding and practical experience with complex machine intelligence and programming concepts we developed the Machine Intelligence Hex (MIHex) project. The associated undergraduate student assignment is about designing and implementing Hex…

Chalup, Stephan K.; Mellor, Drew; Rosamond, Fran

2005-01-01

397

Modern Applications of Machine Learning  

Microsoft Academic Search

Machine learning is one of the older areas of artificial intelligence and concerns the study of computational methods for the discovery of new knowledge and for the management of existing knowledge. Machine learning methods have been applied to various application domains. However, in the few last years due to various technological advances and research efforts (e.g. completion of the Human

George Tzanis; Ioannis Katakis; Ioannis Partalas; Ioannis Vlahavas

2006-01-01

398

Selection of sewing machine operators  

Microsoft Academic Search

50 sewing machine operators from a glove manufacturing concern, 25 from the highest fourth in earnings (at piece rate) and 25 from the lowest fourth, were administered the MacQuarrie Test for Mechanical Ability and the Blum Sewing Machine Test, the latter a simple work-sample test. Supervisors' ratings were obtained for these 50 operators. These ratings and earnings were used as

M. L. Blum

1943-01-01

399

The Blindstitch Machine. Module 11.  

ERIC Educational Resources Information Center

This module on the purpose and use of the blindstitch machine, one in a series on clothing construction for industrial sewing machine operators designed for student self-study, contains three sections. Each section includes the following parts: an introduction, directions, an objective, learning activities, student information, student self-check,…

South Carolina State Dept. of Education, Columbia. Office of Vocational Education.

400

Machine Intelligence Alex S. Taylor  

E-print Network

Machine Intelligence Alex S. Taylor Microsoft Research 7 J. J. Thomson Avenue, Cambridge, CB3 0FB with computing machines as though they exhibited intelligence, at least an intelligence of sorts. Using exam ready to treat as intelligent. Broadly, it is suggested that ordinary, everyday ideas of intelligence

Hunt, Galen

401

CRYOGENIC MACHINING OF KEVLAR COMPOSITES  

Microsoft Academic Search

Previous attempts to machine Kevlar aramid fibre reinforced plastics (KFRP) with conventional cutting tools have proven to be extremely difficult. This has somewhat restricted the material's usage, often negating the advantages of its high strength to weight ratio and fatigue tolerance. The present paper describes a novel technique of machining KFRP under cryogenic conditions with remarkable results compared to those

D. Bhattacharyya; M. N. Allen; S. J. Mander

1993-01-01

402

Machines That Make Books Talk.  

ERIC Educational Resources Information Center

This paper describes playback equipment provided by the National Library Service for the Blind and Physically Handicapped's Talking Books program. The history of these machines is reviewed from 1933 to the present and includes activities during World War II, the introduction of flexible discs and cassettes, descriptions of a variety of machines

Fitzpatrick, Vicki, Ed.

1994-01-01

403

The Machine Scoring of Writing  

ERIC Educational Resources Information Center

This article provides an introduction to the kind of computer software that is used to score student writing in some high stakes testing programs, and that is being promoted as a teaching and learning tool to schools. It sketches the state of play with machines for the scoring of writing, and describes how these machines work and what they do.…

McCurry, Doug

2010-01-01

404

Chemical Aspects of Machining Processes  

Microsoft Academic Search

Machining processes used to create surfaces are influenced by the mechanical, thermal, and chemical loading in the contact zone. In addition, the tribo-physical and tribo-chemical interactions between the cutting tool, workpiece, metalworking fluid and surrounding medium have an influence on the properties of the resulting surface. In order to design efficient machining processes and control the chemical state of the

E. Brinksmeier; D. A. Lucca; A. Walter

2004-01-01

405

Finite State Machines Testing problems Conformance Testing Machine Identification FSM-Based Testing  

E-print Network

Finite State Machines Testing problems Conformance Testing Machine Identification FSM-Based Testing Mousavi: FSM-Based Testing Part II #12;Finite State Machines Testing problems Conformance Testing Machine Identification Outline Finite State Machines Testing problems Conformance Testing Machine Identification Mousavi

Mousavi, Mohammad

406

A study on the machining-parameters optimization of wire electrical discharge machining  

Microsoft Academic Search

A suitable selection of machining parameters for the wire electrical discharge machining (WEDM) process relies heavily on the operators' technologies and experience because of their numerous and diverse range. Machining-parameters tables provided by the machine-tool builder can not meet the operators' requirements, since for an arbitrary desired roughness of the machining surface, they do not provide the optimal machining conditions.

Y. S. Liao; J. T. Huang; H. C. Su

1997-01-01

407

Environmental constituents of Electrical Discharge Machining  

E-print Network

Electrical Discharge Machining (EDM) is a non-traditional process that uses no mechanical forces to machine metals. It is extremely useful in machining hard materials. With the advantages EDM has to offer and its presence ...

Cho, Margaret H. (Margaret Hyunjoo), 1982-

2004-01-01

408

49 CFR 173.174 - Refrigerating machines.  

Code of Federal Regulations, 2010 CFR

...2010-10-01 2010-10-01 false Refrigerating machines. 173.174 Section 173.174 Transportation...Class 1 and Class 7 § 173.174 Refrigerating machines. A refrigerating machine assembled for shipment and containing 7 kg...

2010-10-01

409

7 CFR 58.429 - Washing machine.  

Code of Federal Regulations, 2013 CFR

...2013-01-01 2013-01-01 false Washing machine. 58.429 Section 58.429 Agriculture...Equipment and Utensils § 58.429 Washing machine. When used, the washing machine for cheese cloths and bandages shall be...

2013-01-01

410

48 CFR 908.7103 - Office machines.  

Code of Federal Regulations, 2013 CFR

...2013-10-01 2013-10-01 false Office machines. 908.7103 Section 908.7103 Federal...Acquisition of Special Items 908.7103 Office machines. Acquisitions of office machines by DOE offices and its authorized...

2013-10-01

411

7 CFR 58.429 - Washing machine.  

Code of Federal Regulations, 2012 CFR

...2012-01-01 2012-01-01 false Washing machine. 58.429 Section 58.429 Agriculture...Equipment and Utensils § 58.429 Washing machine. When used, the washing machine for cheese cloths and bandages shall be...

2012-01-01

412

49 CFR 173.174 - Refrigerating machines.  

Code of Federal Regulations, 2011 CFR

...2011-10-01 2011-10-01 false Refrigerating machines. 173.174 Section 173.174 Transportation...Class 1 and Class 7 § 173.174 Refrigerating machines. A refrigerating machine assembled for shipment and containing 7 kg...

2011-10-01

413

48 CFR 908.7103 - Office machines.  

Code of Federal Regulations, 2010 CFR

...2010-10-01 2010-10-01 false Office machines. 908.7103 Section 908.7103 Federal...Acquisition of Special Items 908.7103 Office machines. Acquisitions of office machines by DOE offices and its authorized...

2010-10-01

414

48 CFR 908.7103 - Office machines.  

Code of Federal Regulations, 2011 CFR

...2011-10-01 2011-10-01 false Office machines. 908.7103 Section 908.7103 Federal...Acquisition of Special Items 908.7103 Office machines. Acquisitions of office machines by DOE offices and its authorized...

2011-10-01

415

49 CFR 173.174 - Refrigerating machines.  

Code of Federal Regulations, 2012 CFR

...2012-10-01 2012-10-01 false Refrigerating machines. 173.174 Section 173.174 Transportation...Class 1 and Class 7 § 173.174 Refrigerating machines. A refrigerating machine assembled for shipment and containing 7 kg...

2012-10-01

416

7 CFR 58.429 - Washing machine.  

Code of Federal Regulations, 2011 CFR

...2011-01-01 2011-01-01 false Washing machine. 58.429 Section 58.429 Agriculture...Equipment and Utensils § 58.429 Washing machine. When used, the washing machine for cheese cloths and bandages shall be...

2011-01-01

417

48 CFR 908.7103 - Office machines.  

Code of Federal Regulations, 2014 CFR

...2014-10-01 2014-10-01 false Office machines. 908.7103 Section 908.7103 Federal...Acquisition of Special Items 908.7103 Office machines. Acquisitions of office machines by DOE offices and its authorized...

2014-10-01

418

49 CFR 173.174 - Refrigerating machines.  

Code of Federal Regulations, 2014 CFR

...2014-10-01 2014-10-01 false Refrigerating machines. 173.174 Section 173.174 Transportation...Class 1 and Class 7 § 173.174 Refrigerating machines. A refrigerating machine assembled for shipment and containing 7 kg...

2014-10-01

419

7 CFR 58.429 - Washing machine.  

Code of Federal Regulations, 2014 CFR

...2014-01-01 2014-01-01 false Washing machine. 58.429 Section 58.429 Agriculture...Equipment and Utensils § 58.429 Washing machine. When used, the washing machine for cheese cloths and bandages shall be...

2014-01-01

420

49 CFR 173.174 - Refrigerating machines.  

Code of Federal Regulations, 2013 CFR

...2013-10-01 2013-10-01 false Refrigerating machines. 173.174 Section 173.174 Transportation...Class 1 and Class 7 § 173.174 Refrigerating machines. A refrigerating machine assembled for shipment and containing 7 kg...

2013-10-01

421

48 CFR 908.7103 - Office machines.  

Code of Federal Regulations, 2012 CFR

...2012-10-01 2012-10-01 false Office machines. 908.7103 Section 908.7103 Federal...Acquisition of Special Items 908.7103 Office machines. Acquisitions of office machines by DOE offices and its authorized...

2012-10-01

422

7 CFR 58.429 - Washing machine.  

Code of Federal Regulations, 2010 CFR

...2010-01-01 2010-01-01 false Washing machine. 58.429 Section 58.429 Agriculture...Equipment and Utensils § 58.429 Washing machine. When used, the washing machine for cheese cloths and bandages shall be...

2010-01-01

423

HUMAN MACHINE COOPERATIVE TELEROBOTICS  

SciTech Connect

The remediation and deactivation and decommissioning (D&D) of nuclear waste storage tanks using telerobotics is one of the most challenging tasks faced in environmental cleanup. Since a number of tanks have reached the end of their design life and some of them have leaks, the unstructured, uncertain and radioactive environment makes the work inefficient and expensive. However, the execution time of teleoperation consumes ten to hundred times that of direct contact with an associated loss in quality. Thus, a considerable effort has been expended to improve the quality and efficiency of telerobotics by incorporating into teleoperation and robotic control functions such as planning, trajectory generation, vision, and 3-D modeling. One example is the Robot Task Space Analyzer (RTSA), which has been developed at the Robotics and Electromechanical Systems Laboratory (REMSL) at the University of Tennessee in support of the D&D robotic work at the Oak Ridge National Laboratory and the National Energy Technology Laboratory. This system builds 3-D models of the area of interest in task space through automatic image processing and/or human interactive manual modeling. The RTSA generates a task plan file, which describes the execution of a task including manipulator and tooling motions. The high level controller of the manipulator interprets the task plan file and executes the task automatically. Thus, if the environment is not highly unstructured, a tooling task, which interacts with environment, will be executed in the autonomous mode. Therefore, the RTSA not only increases the system efficiency, but also improves the system reliability because the operator will act as backstop for safe operation after the 3-D models and task plan files are generated. However, unstructured conditions of environment and tasks necessitate that the telerobot operates in the teleoperation mode for successful execution of task. The inefficiency in the teleoperation mode led to the research described as Human Machine Cooperative Telerobotics (HMCTR). The HMCTR combines the telerobot with robotic control techniques to improve the system efficiency and reliability in teleoperation mode. In this topical report, the control strategy, configuration and experimental results of Human Machines Cooperative Telerobotics (HMCTR), which modifies and limits the commands of human operator to follow the predefined constraints in the teleoperation mode, is described. The current implementation is a laboratory-scale system that will be incorporated into an engineering-scale system at the Oak Ridge National Laboratory in the future.

William R. Hamel; Spivey Douglass; Sewoong Kim; Pamela Murray; Yang Shou; Sriram Sridharan; Ge Zhang; Scott Thayer; Rajiv V. Dubey

2003-06-30

424

Upgrading the capabilities of existing machine tools for precision machining  

SciTech Connect

A number of two-axis turning machines at the Oak Ridge Y-12 Plant have undergone upgrading as a means of meeting the needs for parts with tolerances that were more restrictive than the capability of the basic machine. The level of upgrading has ranged from changing a single machine characteristic to doing a complete overhaul of the slides, drives, spindle, and control system. The features available for the up-grading process include: tool setters, air bearing spindles and slides, pressurized oil bearing slides, electric dc torque motor drives, linear motor slide drives, eddy current spindle drives, laser feedback, vibration-isolation machine platforms, and computer numerical control (CNC) systems. Actual case histories are presented which show the levels of performance achieved with the various modifications. A discussion of the advantages and disadvantages of the various options is included.

Barkman, W.E.

1982-05-01

425

Slide system for machine tools  

DOEpatents

The present invention relates to a machine tool which permits the machining of nonaxisymmetric surfaces on a workpiece while rotating the workpiece about a central axis of rotation. The machine tool comprises a conventional two-slide system (X-Y) with one of these slides being provided with a relatively short travel high-speed auxiliary slide which carries the material-removing tool. The auxiliary slide is synchronized with the spindle speed and the position of the other two slides and provides a high-speed reciprocating motion required for the displacement of the cutting tool for generating a nonaxisymmetric surface at a selected location on the workpiece.

Douglass, Spivey S. (Oak Ridge, TN); Green, Walter L. (Knoxville, TN)

1982-01-01

426

On Parallelism in Turing Machines  

Microsoft Academic Search

A model of parallel computation based on a generalization of nondeterminism in Turing machines is introduced. Complexity classes \\/\\/T(n)-TIME, \\/\\/L(n)-SPACE, \\/\\/LOGSPACE, \\/\\/PTIME, etc. are defined for these machines in a way analogous to T(n)-TIME, L(n)-SPACE, LOGSPACE, PTIME, etc. for deterministic machines. It is shown that, given appropriate honesty conditions, L(n)-SPACE ? \\/\\/L(n)2-TIME T(n)-TIME ? \\/\\/log T(n)-SPACE \\/\\/L(n)-SPACE ? exp L(n)-TIME

Dexter Kozen

1976-01-01

427

Virtual Machine Language  

NASA Technical Reports Server (NTRS)

Virtual Machine Language (VML) is a mission-independent, reusable software system for programming for spacecraft operations. Features of VML include a rich set of data types, named functions, parameters, IF and WHILE control structures, polymorphism, and on-the-fly creation of spacecraft commands from calculated values. Spacecraft functions can be abstracted into named blocks that reside in files aboard the spacecraft. These named blocks accept parameters and execute in a repeatable fashion. The sizes of uplink products are minimized by the ability to call blocks that implement most of the command steps. This block approach also enables some autonomous operations aboard the spacecraft, such as aerobraking, telemetry conditional monitoring, and anomaly response, without developing autonomous flight software. Operators on the ground write blocks and command sequences in a concise, high-level, human-readable programming language (also called VML ). A compiler translates the human-readable blocks and command sequences into binary files (the operations products). The flight portion of VML interprets the uplinked binary files. The ground subsystem of VML also includes an interactive sequence- execution tool hosted on workstations, which runs sequences at several thousand times real-time speed, affords debugging, and generates reports. This tool enables iterative development of blocks and sequences within times of the order of seconds.

Grasso, Christopher; Page, Dennis; O'Reilly, Taifun; Fteichert, Ralph; Lock, Patricia; Lin, Imin; Naviaux, Keith; Sisino, John

2005-01-01

428

Virtual machine performance benchmarking.  

PubMed

The attractions of virtual computing are many: reduced costs, reduced resources and simplified maintenance. Any one of these would be compelling for a medical imaging professional attempting to support a complex practice on limited resources in an era of ever tightened reimbursement. In particular, the ability to run multiple operating systems optimized for different tasks (computational image processing on Linux versus office tasks on Microsoft operating systems) on a single physical machine is compelling. However, there are also potential drawbacks. High performance requirements need to be carefully considered if they are to be executed in an environment where the running software has to execute through multiple layers of device drivers before reaching the real disk or network interface. Our lab has attempted to gain insight into the impact of virtualization on performance by benchmarking the following metrics on both physical and virtual platforms: local memory and disk bandwidth, network bandwidth, and integer and floating point performance. The virtual performance metrics are compared to baseline performance on "bare metal." The results are complex, and indeed somewhat surprising. PMID:21207096

Langer, Steve G; French, Todd

2011-10-01

429

Semismooth support vector machines.  

SciTech Connect

The linear support vector machine can be posed as a quadratic program in a variety of ways. In this paper, we look at a formulation using the two-norm for the misclassification error that leads to a positive definite quadratic program with a single equality constraint when the Wolfe dual is taken. The quadratic term is a small rank update to a positive definite matrix. We reformulate the optimality conditions as a semismooth system of equations using the Fischer-Burmeister function and apply a damped Newton method to solve the resulting problem. The algorithm is shown to converge from any starting point with a Q-quadratic rate of convergence. At each iteration, we use the Sherman-Morrison-Woodbury update formula to solve a single linear system of equations. Significant computational savings are realized as the inactive variables are identified and exploited during the solution process. Results for a 60 million variable problem are presented, demonstrating the effectiveness of the proposed method on a personal computer.

Ferris, M. C.; Munson, T. S.; Mathematics and Computer Science; Univ. of Wisconsin

2004-09-01

430

Fatigue test machine  

NASA Astrophysics Data System (ADS)

This invention relates to an apparatus for testing materials under combined static and dynamic loads. Materials used in rotating components of, for example, jet engines are subjected to unusually severe environmental conditions during their operational lifetimes. Components such as disks and blades are subjected to high temperature excursions, high levels of 'steady' stress from centrifugal loads (low cycle stress), as well as high levels of high frequency 'dynamic' stress from resonant vibration response (high cycle stress). The thermal-mechanical cycling of the component material can lead to initiation and propagation of cracks at voids, defects or scratches. The crack initiation and propagation characteristics of materials used in jet engine components vary widely, according to whether the material is more or less ductile, and depend on temperature, low cycle stress, high cycle stress, frequency, dwell time, local atmospheric conditions and many other parameters. This abstract discloses fatigue testing machine for testing materials under combined static and dynamic loads. The mach ine comprises a right circular ring, a pair of specimen clamps adapted for slidably fitting into diametrically opposed openings in the ring, a support cradle for the ring and a shaker. The clamps comprises means for applying a static load to a specimen clamped therebetween.

Jones, D. I. G.

1985-12-01

431

Lubrication of Machine Elements  

NASA Technical Reports Server (NTRS)

The understanding of hydrodynamic lubrication began with the classical experiments of Tower and Petrov. Reynolds used a reduced form of the Navier-Stokes equations and the continuity equation to generate a second order differential equation for the pressure in the narrow, converging gap of a bearing contact. Such a pressure enables a load to be transmitted between the surfaces with very low friction since the surfaces are completely separated by a film of fluid. In such a situation it is the physical properties of the lubricant, notably the dynamic viscosity, that dictate the behavior of the contact. The understanding of boundary lubrication is normally attributed to Hardy and Doubleday. In boundary lubrication it is the physical and chemical properties of thin films of molecular proportions and the surfaces to which they are attached that determine contact behavior. The lubricant viscosity is not an influential parameter. Research is devoted to a better understanding and more precise definition of other lubrication regimes between these extremes. One such regime, elastohydrodynamic lubrication, occurs in nonconformal contacts, where the pressures are high and the bearing surfaces deform elastically. In this situation the viscosity of the lubricant may raise considerably, and this further assists the formation of an effective fluid film. The science of these three lubrication regimes (hydrodynamic, elastohydrodynamic, and boundary) are described and the manner in which this science is used in the design of machine elements is examined.

Hamrock, B. J.

1984-01-01

432

Size reduction machine  

SciTech Connect

The Size Reduction Machine (SRM) is a mobile platform capable of shearing various shapes and types of metal components at a variety of elevations. This shearing activity can be performed without direct physical movement and placement of the shear head by the operator. The base unit is manually moved and roughly aligned to each cut location. The base contains the electronics: hydraulic pumps, servos, and actuators needed to move the shear-positioning arm. The movable arm allows the shear head to have six axes of movement and to cut to within 4 inches of a wall surface. The unit has a slick electrostatic capture coating to assist in external decontamination. Internal contamination of the unit is controlled by a high-efficiency particulate air (HEPA) filter on the cooling inlet fan. The unit is compact enough to access areas through a 36-inch standard door opening. This paper is an Innovative Technology Summary Report designed to provide potential users with the information they need to quickly determine if a technology would apply to a particular environmental management problem. They also are designed for readers who may recommend that a technology be considered by prospective users.

Fricke, V.

1999-12-15

433

Time Machine at the LHC  

E-print Network

Recently, black hole and brane production at CERN's Large Hadron Collider (LHC) has been widely discussed. We suggest that there is a possibility to test causality at the LHC. We argue that if the scale of quantum gravity is of the order of few TeVs, proton-proton collisions at the LHC could lead to the formation of time machines (spacetime regions with closed timelike curves) which violate causality. One model for the time machine is a traversable wormhole. We argue that the traversable wormhole production cross section at the LHC is of the same order as the cross section for the black hole production. Traversable wormholes assume violation of the null energy condition (NEC) and an exotic matter similar to the dark energy is required. Decay of the wormholes/time machines and signatures of time machine events at the LHC are discussed.

I. Ya. Aref'eva; I. V. Volovich

2007-10-25

434

Diamond turning machine controller implementation  

SciTech Connect

The standard controller for a Pnuemo ASG 2500 Diamond Turning Machine, an Allen Bradley 8200, has been replaced with a custom high-performance design. This controller consists of four major components. Axis position feedback information is provided by a Zygo Axiom 2/20 laser interferometer with 0.1 micro-inch resolution. Hardware interface logic couples the computers digital and analog I/O channels to the diamond turning machine`s analog motor controllers, the laser interferometer, and other machine status and control information. It also provides front panel switches for operator override of the computer controller and implement the emergency stop sequence. The remaining two components, the control computer hardware and software, are discussed in detail below.

Garrard, K.P.; Taylor, L.W.; Knight, B.F.; Fornaro, R.J.

1988-12-01

435

Z Machine at Sandia Labs  

SciTech Connect

Sandia Labs' Z machine is the largest laboratory source of x-rays in the world. For the few nanoseconds of a Z Machine test, its electrical output equals the output of 50x the electrical generating stations of all the power plants on earth. The Z Machine complex encompasses an area roughly the size of a major college basketball arena. Originally created to validate nuclear weapons models, the Z Machine is also considered a "dark horse" in the race for viable fusion energy production. After the famous "arcs and sparks" photo of Z (a photo no longer possible after its refurbishment), this is a fast-motion video of workers completing Z's recent refurbishment.

2007-10-17

436

Building and simulating protein machines  

NASA Astrophysics Data System (ADS)

Glycolysis is a central metabolic pathway, present in almost all organisms, that produces energy. The pathway has been extensively investigated by biochemists. There is a significant body of structural and biochemical information about this pathway. The complete pathway is a ten step process. At each step, a specific chemical reaction is catalyzed by a specific enzyme. Fructose bisphosphate aldolase (FBA) and triosephosphate isomerase (TIM) catalyze the fourth and the fifth steps on the pathway. This thesis investigates the possible substrate transfer mechanism between FBA and TIM. FBA cleaves its substrate, the six-carbon fructose-1,6-bisphosphate (FBP), into two three-carbon products -- glyceraldehydes 3-phosphate (GAP) and dihydroxy acetone phosphate (DHAP). One component of these two products, DHAP, is the substrate for TIM and the other component GAP goes directly to GAPDH, the subsequent enzyme on the pathway. TIM converts DHAP to GAP and delivers the product to GAPDH. I employ Elastic Network Models (ENM) to investigate the mechanistic and dynamic aspects of the functionality of FBA and TIM enzymes -- (1) the effects of the oligomerization of these two enzymes on their functional dynamics and the coordination of the individual protein's structural components along the functional region; and (2) the mechanistic synchrony of these two protein machines that may enable them to operate in a coordinated fashion as a conjugate machine -- transferring the product from FBA as substrate to TIM. A macromolecular machine comprised of FBA and TIM will facilitate the substrate catalysis mechanism and the product flow between FBA and TIM. Such a machine could be used as a functional unit in building a larger a machine for the structural modeling of the whole glycolysis pathway. Building such machines for the glycolysis pathway may reveal the interplay of the enzymes as a complete machine. Also the methods and insights developed from the efforts to build such large machines could be applied to build macromolecular structures for other biologically important clusters of interacting enzymes centered around individual metabolic pathways.

Katebi, Ataur Rahim

437

The Gamma Database Machine Project  

Microsoft Academic Search

This paper describes the design of the Gamma database machine and the techniques employed in its implementation.Gamma is a relational database machine currently operating on an Intel iPSC\\/2 hypercube with 32 processorsand 32 disk drives. Gamma employs three key technical ideas which enable the architecture to be scaled to100s of processors. First, all relations are horizontally partitioned across multiple disk

David J. Dewitt; Shahram Ghandeharizadeh; Donovan A. Schneider; Allan Bricker; Hui-i Hsiao; Rick Rasmussen

1990-01-01

438

The gamma database machine project  

Microsoft Academic Search

ABSTRACT This paper describes the design of the Gamma,database machine,and the techniques employed,in its implementation. Gamma,is a relational database machine,currently operating on an Intel iPSC\\/2 hypercube,with 32 processors and 32 disk drives. Gamma,employs,three key technical ideas which enable the architecture to be scaled to 100s of processors. First, all relations are horizontally partitioned across multiple disk drives enabling relations to

D. Dewitt; S. Ghandeharizadeh; D. Schneider; A. Bricker; H Hsiao

1988-01-01

439

The J-Machine Network  

Microsoft Academic Search

The J-Machine network is a 3-D mesh employing worm- hole routing and virtual channels to provide two network priorities. Each network channel is 9 bits wide and oper- ates at 32MHz. Each J-Machine node contains network routers that guide messages between the six bidirectional channels incident on each node, and a network interface that handles messages originating or terminating at

Peter R. Nuth; William J. Dally

1992-01-01

440

The M-Machine multicomputer  

Microsoft Academic Search

The M–Machine is an experimental multicomputer being developed to test architectural concepts motivated by the constraints of modern semiconductor technology and the demands of programming systems. The M-Machine computing nodes are connetted with a 3-D mesh nebvork; each node is a multithreaded processor incorporating 12&nction units, on-chip cache, and local memory. The mtdtiple finction units are used to exploit both

Marco Fillo; Stephen W. Keckler; William J. Dally; Nicholas P. Carter; Andrew Chang; Yevgeny Gurevich; Whay Sing Lee

1995-01-01

441

Support Vector Machines – An Introduction  

Microsoft Academic Search

This is a book about learning from empirical data (i.e., examples, samples, measurements, records, patterns or observations) by applying support vector machines (SVMs) a.k.a. kernel machines. The basic aim of this introduction 1 is to give, as far as possible, a condensed (but systematic) presentation of a novel learning paradigm embodied in SVMs. Our focus will be on the constructive

V. Kecman

442

Glocalization pursuit support vector machine  

Microsoft Academic Search

Graph-based methods have aroused wide interest in pattern recognition and machine learning, which capture the structural information\\u000a in data into classifier design through defining a graph over the data and assuming label smoothness over the graph. Laplacian\\u000a Support Vector Machine (LapSVM) is a representative of these methods and an extension of the traditional SVM by optimizing\\u000a a new objective additionally

Hui Xue; Songcan Chen

443

Model-based machine learning  

PubMed Central

Several decades of research in the field of machine learning have resulted in a multitude of different algorithms for solving a broad range of problems. To tackle a new application, a researcher typically tries to map their problem onto one of these existing methods, often influenced by their familiarity with specific algorithms and by the availability of corresponding software implementations. In this study, we describe an alternative methodology for applying machine learning, in which a bespoke solution is formulated for each new application. The solution is expressed through a compact modelling language, and the corresponding custom machine learning code is then generated automatically. This model-based approach offers several major advantages, including the opportunity to create highly tailored models for specific scenarios, as well as rapid prototyping and comparison of a range of alternative models. Furthermore, newcomers to the field of machine learning do not have to learn about the huge range of traditional methods, but instead can focus their attention on understanding a single modelling environment. In this study, we show how probabilistic graphical models, coupled with efficient inference algorithms, provide a very flexible foundation for model-based machine learning, and we outline a large-scale commercial application of this framework involving tens of millions of users. We also describe the concept of probabilistic programming as a powerful software environment for model-based machine learning, and we discuss a specific probabilistic programming language called Infer.NET, which has been widely used in practical applications. PMID:23277612

Bishop, Christopher M.

2013-01-01

444

Nano-Machines Achieve Huge Mechanical Breakthrough  

E-print Network

NANO TECH Nano-Machines Achieve Huge Mechanical Breakthrough Dublin, Ireland (SPX) Sep 08, 2005 that use molecular 'nano'-machines of this kind to help perform physical tasks. Nano-machines could also owners set to return to battered Orleans l Six dead, two missing after heavy rains hit Page 1 of 3Nano-Machines

Leigh, David A.

445

Experimental study of machining system: dynamic characterization  

Microsoft Academic Search

In the workspace model of machining an experimental procedure is implemented to determine the elastic behaviour of the machining system. In an other work we have proposed a static characterization of the machining system. In this paper a dynamic characterization and vibration analysis have long been used for the detection and identification of machine tool condition. The natural frequencies of

Miron Zapciu; Olivier Cahuc; Claudiu-Florinel Bisu; Alain Gérard; Jean-Yves K'Nevez

2009-01-01

446

Nonlinear Feed Effect in Machining Chatter Analysis  

Microsoft Academic Search

Regenerative chatter is a major limitation to the productivity and quality of machining operations due to the excessive rate of tool wear and scrap parts which are produced. Machining chatter analysis techniques examine the stability of the closed-loop model (force process and machine tool-part structure) of the machining operation to determine the stable process parameter space. Almost all chatter analysis

Robert G. Landers; A. Galip Ulsoy

2008-01-01

447

The Emerging Web of Social Machines  

Microsoft Academic Search

We define a notion of social machine and envisage an algebra that can describe networks of such. To start with, social machines are defined as tuples of input, output, processes, constraints, state, requests and responses; apart from defining the machines themselves, we define their connectors and conditionals that can be used to describe the interactions between any number of machines

Silvio R. L. Meira; Vanilson A. A. Buregio; Leandro M. Nascimento; Elaine Figueiredo; Misael Neto; Bruno Encarnacao; Vinicius Cardoso Garcia

2011-01-01

448

Web Mining: Machine Learning for Web Applications.  

ERIC Educational Resources Information Center

Presents an overview of machine learning research and reviews methods used for evaluating machine learning systems. Ways that machine-learning algorithms were used in traditional information retrieval systems in the "pre-Web" era are described, and the field of Web mining and how machine learning has been used in different Web mining applications…

Chen, Hsinchun; Chau, Michael

2004-01-01

449

Standard Operating Procedure (SOP) -Milling Machine  

E-print Network

Standard Operating Procedure (SOP) - Milling Machine · Keep all guards in place while operating the machine. · While operating the milling machine allow no one else to touch it. · Keep hands away from moving cutting tools. · Do not make measurements of the stock while the milling machine is powered. · Do

Veiga, Pedro Manuel Barbosa

450

Virtualization in the age of heterogeneous machines  

Microsoft Academic Search

Since their invention over 40 years ago, virtual machines have been used to virtualize one or more von Neumann processors and their associated peripherals. System virtual machines provide the illusion that the user has their own instance of a physical machine with a given instruction set architecture (ISA). Process virtual machines provide the illusion of running on a synthetic architecture

David F. Bacon; Perry Cheng; Rodric Rabbah; Sunil Shukla

2011-01-01

451

Machine Learning and NLP Research Interests  

E-print Network

Machine Learning and NLP Research Interests Machine Learning for Language Learning and Processing #12;Machine Learning and NLP Research Interests 1 Machine Learning and NLP Latent Variables Multi Learning and NLP Research Interests Latent Variables Multi-class and Structured Variables Discrete, Sparse

Edinburgh, University of

452

Electrode Wear Process in Electrical Discharge Machinings  

Microsoft Academic Search

This paper deals with a synthetic consideration of electrode wear phenomena in electrical discharge machining. Time dependance of an electrode shape was observed through on-the-machine measurement. While the electrode wears at the edge portion in the beginning of machining, it grows at the flat portion in the longitudinal direction. In the stationary state of machining, the wear rate of an

Naotake Mohri; Masayuki Suzuki; Masanori Furuya; Nagao Saito; Akira Kobayashi

1995-01-01

453

Comparative analysis of Double Stator Switched Reluctance Machine and Permanent Magnet Synchronous machine  

Microsoft Academic Search

High torque density Permanent Magnet machine are widely used in practice. However, the rising cost of high energy rare earth permanent magnet material stimulates the needs for electrical machines using less or no permanent magnet. Double Stator Switched Reluctance Machine is a novel high torque density reluctance machine. This paper provides a comparison between surface mount Permanent Magnet Synchronous Machine

Wei Wang; Chenjie Lin; Babak Fahimi

2012-01-01

454

Student Perceptions of the Shift from Soft Drink Vending Machines to Milk Vending Machines in Schools  

Microsoft Academic Search

Soft drink vending machines are available in many schools across the nation. Some schools have recently removed soft drink vending machines and replaced them with milk vending machines. The purpose of this study was to investigate high school students’ (n = 84) perceptions of the shift from soft drink vending machines to milk vending machines in schools.\\u000aStudents in this

Jillian B Trapini

2007-01-01

455

Open heart surgery  

MedlinePLUS

... and a camera to perform the surgery. During robot-assisted valve surgery, the surgeon makes two to ... results than traditional surgery methods. You will not need to be on a heart-lung machine for ...

456

The Bioengineering Program Bioengineers (also called biomedical or biomechanical  

E-print Network

The Bioengineering Program Bioengineers (also called biomedical or biomechanical engineers) use that improves human health. Bioengineers design and improve hospital, medical, and surgical equipment used systems, dialysis and heart-lung machines, and surgery- assisting robotic devices. The Bioengineering

Lu, Yi

457

Game-powered machine learning.  

PubMed

Searching for relevant content in a massive amount of multimedia information is facilitated by accurately annotating each image, video, or song with a large number of relevant semantic keywords, or tags. We introduce game-powered machine learning, an integrated approach to annotating multimedia content that combines the effectiveness of human computation, through online games, with the scalability of machine learning. We investigate this framework for labeling music. First, a socially-oriented music annotation game called Herd It collects reliable music annotations based on the "wisdom of the crowds." Second, these annotated examples are used to train a supervised machine learning system. Third, the machine learning system actively directs the annotation games to collect new data that will most benefit future model iterations. Once trained, the system can automatically annotate a corpus of music much larger than what could be labeled using human computation alone. Automatically annotated songs can be retrieved based on their semantic relevance to text-based queries (e.g., "funky jazz with saxophone," "spooky electronica," etc.). Based on the results presented in this paper, we find that actively coupling annotation games with machine learning provides a reliable and scalable approach to making searchable massive amounts of multimedia data. PMID:22460786

Barrington, Luke; Turnbull, Douglas; Lanckriet, Gert

2012-04-24

458

Reusable State Machine Code Generator  

NASA Astrophysics Data System (ADS)

The State Machine model is frequently used to represent the behaviour of a system, allowing one to express and execute this behaviour in a deterministic way. A graphical representation such as a UML State Chart diagram tames the complexity of the system, thus facilitating changes to the model and communication between developers and domain experts. We present a reusable state machine code generator, developed by the Universidad Técnica Federico Santa María and the European Southern Observatory. The generator itself is based on the open source project architecture, and uses UML State Chart models as input. This allows for a modular design and a clean separation between generator and generated code. The generated state machine code has well-defined interfaces that are independent of the implementation artefacts such as the middle-ware. This allows using the generator in the substantially different observatory software of the Atacama Large Millimeter Array and the ESO Very Large Telescope. A project-specific mapping layer for event and transition notification connects the state machine code to its environment, which can be the Common Software of these projects, or any other project. This approach even allows to automatically create tests for a generated state machine, using techniques from software testing, such as path-coverage.

Hoffstadt, A. A.; Reyes, C.; Sommer, H.; Andolfato, L.

2010-12-01

459

A NEW METHOD FOR MACHINING OF ELECTRICALLY NONCONDUCTIVE WORKPIECES USING ELECTRIC DISCHARGE MACHINING TECHNIQUE  

Microsoft Academic Search

In this study, a new method for machining of nonconductive ceramic workpieces in electric discharge machining (EDM) was developed. Machining surfaces of nonconductive workpieces were coated with a conductive layer (CL) and graphite powder was added to dielectric fluid for machining. Al2O3, ZrO2, SiC, B4C and glass workpiece samples were machined by using the method. Different machining conditions were tested

Gokhan Kucukturk; Can Cogun

2010-01-01

460

A study design to assess the safety and efficacy of on-pump versus off-pump coronary bypass grafting: the ROOBY trial  

Microsoft Academic Search

Background Since the late 1960s, coronary artery bypass graft (CABG-only) procedures were traditionally performed using a heart-lung machine on an arrested heart (on-pump). Over the past decade, an increasing number CABG-only procedures were performed on a beating heart (off-pump). Advocates of the off-pump approach expect to reduce many of the adverse side effects related to using the heart-lung machine, while

Dimitri Novitzky; A Laurie Shroyer; Joseph F Collins; Gerald O McDonald; John Lucke; Brack Hattler; Elizabeth Kozora; Douglas D Bradham; Janet Baltz; Frederick L Grover

2007-01-01

461

Machine learning methods in chemoinformatics  

PubMed Central

Machine learning algorithms are generally developed in computer science or adjacent disciplines and find their way into chemical modeling by a process of diffusion. Though particular machine learning methods are popular in chemoinformatics and quantitative structure–activity relationships (QSAR), many others exist in the technical literature. This discussion is methods-based and focused on some algorithms that chemoinformatics researchers frequently use. It makes no claim to be exhaustive. We concentrate on methods for supervised learning, predicting the unknown property values of a test set of instances, usually molecules, based on the known values for a training set. Particularly relevant approaches include Artificial Neural Networks, Random Forest, Support Vector Machine, k-Nearest Neighbors and naïve Bayes classifiers. WIREs Comput Mol Sci 2014, 4:468–481. How to cite this article: WIREs Comput Mol Sci 2014, 4:468–481. doi:10.1002/wcms.1183 PMID:25285160

Mitchell, John B O

2014-01-01

462

Minimal universal quantum heat machine  

E-print Network

In traditional thermodynamics the Carnot cycle yields the ideal performance bound of heat engines and refrigerators. We propose and analyze a minimal model of a heat machine that can play a similar role in quantum regimes. The minimal model consists of a single two-level system with periodically modulated energy splitting that is permanently, weakly, coupled to two spectrally-separated heat baths at different temperatures. The equation of motion allows to compute the stationary power and heat currents in the machine consistently with the second-law of thermodynamics. This dual-purpose machine can act as either an engine or a refrigerator (heat pump) depending on the modulation rate. In both modes of operation the maximal Carnot efficiency is reached at zero power. We study the conditions for finite-time optimal performance for several variants of the model. Possible realizations of the model are discussed.

David Gelbwaser-Klimovsky; Robert Alicki; Gershon Kurizki

2013-01-29

463

Minimal universal quantum heat machine.  

PubMed

In traditional thermodynamics the Carnot cycle yields the ideal performance bound of heat engines and refrigerators. We propose and analyze a minimal model of a heat machine that can play a similar role in quantum regimes. The minimal model consists of a single two-level system with periodically modulated energy splitting that is permanently, weakly, coupled to two spectrally separated heat baths at different temperatures. The equation of motion allows us to compute the stationary power and heat currents in the machine consistent with the second law of thermodynamics. This dual-purpose machine can act as either an engine or a refrigerator (heat pump) depending on the modulation rate. In both modes of operation, the maximal Carnot efficiency is reached at zero power. We study the conditions for finite-time optimal performance for several variants of the model. Possible realizations of the model are discussed. PMID:23410316

Gelbwaser-Klimovsky, D; Alicki, R; Kurizki, G

2013-01-01

464

Machine learning methods in chemoinformatics.  

PubMed

Machine learning algorithms are generally developed in computer science or adjacent disciplines and find their way into chemical modeling by a process of diffusion. Though particular machine learning methods are popular in chemoinformatics and quantitative structure-activity relationships (QSAR), many others exist in the technical literature. This discussion is methods-based and focused on some algorithms that chemoinformatics researchers frequently use. It makes no claim to be exhaustive. We concentrate on methods for supervised learning, predicting the unknown property values of a test set of instances, usually molecules, based on the known values for a training set. Particularly relevant approaches include Artificial Neural Networks, Random Forest, Support Vector Machine, k-Nearest Neighbors and naïve Bayes classifiers. PMID:25285160

Mitchell, John B O

2014-09-01

465

Simple Machines in the Community  

NSDL National Science Digital Library

The community can be a powerful context and mini-laboratory for cultivating students' common understandings of science and mathematics. On the island of Panay in the Philippines, the community was the starting place for a group of fifth- and sixth-grade students to explore simple machines in their daily lives. What students learned in the process became the basis for developing the set of culturally relevant lessons on simple machines described in this article. Each of the examples that follow features a simple machine found in the community, an explanation of how it works, a guiding-inquiry question, and a follow-up activity designed to foster students' exploration of this question.

Aris Laroder

2008-03-01

466

Dry machinability of aluminum alloys.  

SciTech Connect

Adverse effects of the use of cutting fluids and environmental concerns with regard to cutting fluid disposability is compelling industry to adopt Dry or near Dry Machining, with the aim of eliminating or significantly reducing the use of metal working fluids. Pending EPA regulations on metal cutting, dry machining is becoming a hot topic of research and investigation both in industry and federal research labs. Although the need for dry machining may be apparent, most of the manufacturers still consider dry machining to be impractical and even if possible, very expensive. This perception is mainly due to lack of appropriate cutting tools that can withstand intense heat and Built-up-Edge (BUE) formation during dry machining. The challenge of heat dissipation without coolant requires a completely different approach to tooling. Special tooling utilizing high-performance multi-layer, multi-component, heat resisting, low friction coatings could be a plausible answer to the challenge of dry machining. In pursuit of this goal Argonne National Labs has introduced Nano-crystalline near frictionless carbon (NFC) diamond like coatings (DLC), while industrial efforts have led to the introduction of composite coatings such as titanium aluminum nitride (TiAlN), tungsten carbide/carbon (WC/C) and others. Although, these coatings are considered to be very promising, they have not been tested either from tribological or from dry machining applications point of view. As such a research program in partnership with federal labs and industrial sponsors has started with the goal of exploring the feasibility of dry machining using the newly developed coatings such as Near Frictionless Carbon Coatings (NFC), Titanium Aluminum Nitride (TiAlN), and multi-layer multicomponent nano coatings such as TiAlCrYN and TiAlN/YN. Although various coatings are under investigation as part of the overall dry machinability program, this extended abstract deals with a systematic investigation of dry machinability of Aluminum 6061 and 2024 using uncoated carbide, TiN coated carbide, and TiAlN coated carbide inserts. Central Composite Design (CCD) is used to study the effect of speed, feed, depth of cut, workpiece material, and cutting tool material on the resulting forces, surface finish, temperature, chip morphology and tool wear. Each of the machining responses is measured and compared under 15 different machining conditions. Results from CCD experiments have been used to develop linear and logarithmic models for forces (Fx, Fy, Fz, & Fr) surface finish (Ra), and temperature. Furthermore, chip morphology and tool wear have also been compared. From the comparison of forces, surface finish, temperature, chip morphology, tool wear and the corresponding statistical models, it is clear that in general TiAlN results in lower forces, better surface finish, greater fragmented chips, and lesser tool wear.

Shareef, I.; Natarajan, M.; Ajayi, O. O.; Energy Technology; Department of IMET

2005-01-01

467

Rube Goldberg and the Meaning of Machines  

NSDL National Science Digital Library

Simple and compound machines are designed to make work easier. When we encounter a machine that does not fit this understanding, the so-called machine seems absurd. Through the cartoons of Rube Goldberg, students are engaged in critical thinking about the way his inventions make simple tasks even harder to complete. As the final lesson in the simple machines unit, the study of Rube Goldberg machines can help students evaluate the importance and usefulness of the many machines in the world around them.

2014-09-18

468

Mobile machine hazardous working zone warning system  

SciTech Connect

A warning system is provided for a mobile working machine to alert an individual of a potentially dangerous condition in the event the individual strays into a hazardous working zone of the machine. The warning system includes a transmitter mounted on the machine and operable to generate a uniform magnetic field projecting beyond an outer periphery of the machine in defining a hazardous working zone around the machine during operation thereof. A receiver, carried by the individual and activated by the magnetic field, provides an alarm signal to alert the individual when he enters the hazardous working zone of the machine.

Schiffbauer, William H. (Connellsville, PA); Ganoe, Carl W. (Pittsburgh, PA)

1999-01-01

469

Mobile machine hazardous working zone warning system  

DOEpatents

A warning system is provided for a mobile working machine to alert an individual of a potentially dangerous condition in the event the individual strays into a hazardous working zone of the machine. The warning system includes a transmitter mounted on the machine and operable to generate a uniform magnetic field projecting beyond an outer periphery of the machine in defining a hazardous working zone around the machine during operation. A receiver, carried by the individual and activated by the magnetic field, provides an alarm signal to alert the individual when he enters the hazardous working zone of the machine. 3 figs.

Schiffbauer, W.H.; Ganoe, C.W.

1999-08-17

470

On Training Deep Boltzmann Machines  

E-print Network

The deep Boltzmann machine (DBM) has been an important development in the quest for powerful "deep" probabilistic models. To date, simultaneous or joint training of all layers of the DBM has been largely unsuccessful with existing training methods. We introduce a simple regularization scheme that encourages the weight vectors associated with each hidden unit to have similar norms. We demonstrate that this regularization can be easily combined with standard stochastic maximum likelihood to yield an effective training strategy for the simultaneous training of all layers of the deep Boltzmann machine.

Desjardins, Guillaume; Bengio, Yoshua

2012-01-01

471

Moving Along With Simple Machines A Lesson in Simple Machines  

NSDL National Science Digital Library

The purpose of this activity is to allow students to study simple machines, how they operate and how they differ from each other. This activity/lesson was developed by a K-12 science teacher in the American Physiological SocietyÂ?s 2010 Frontiers in Physiology Program. For more information on this program, please visit www.frontiersinphys.org.

Ms. Josefina Goodwin (Raleigh Egypt High School)

2011-04-01

472

What Can Turing Machines Do? How powerful are Turing machines?  

E-print Network

, but it is a scientific "law" akin to Peano's axioms, Newton's laws of motion, the periodic table, evolution, etc by what we intuitively consider an algorithm, that cannot be performed by a Turing machine. 3. Alternative. These laws or theories are not logically deduced, but they are plausible models that explain much of our

Bylander, Tom

473

Exploring Machin's Approximation of Exploring Machin's Approximation of  

E-print Network

#12;Exploring Machin's Approximation of Precursors Method of Exhaustion `a la Archimedes Archimedes of Precursors Method of Exhaustion `a la Archimedes Archimedes of Syracuse ( 287­212 BC) approximated la Archimedes Archimedes of Syracuse ( 287­212 BC) approximated by the Method of Exhaustion: 3

Knaust, Helmut

474

The Perfect Science Machine  

NASA Astrophysics Data System (ADS)

ESO celebrates 10 years since First Light of the VLT Today marks the 10th anniversary since First Light with ESO's Very Large Telescope (VLT), the most advanced optical telescope in the world. Since then, the VLT has evolved into a unique suite of four 8.2-m Unit Telescopes (UTs) equipped with no fewer than 13 state-of-the-art instruments, and four 1.8-m moveable Auxiliary Telescopes (ATs). The telescopes can work individually, and they can also be linked together in groups of two or three to form a giant 'interferometer' (VLTI), allowing astronomers to see details corresponding to those from a much larger telescope. Green Flash at Paranal ESO PR Photo 16a/08 The VLT 10th anniversary poster "The Very Large Telescope array is a flagship facility for astronomy, a perfect science machine of which Europe can be very proud," says Tim de Zeeuw, ESO's Director General. "We have built the most advanced ground-based optical observatory in the world, thanks to the combination of a long-term adequately-funded instrument and technology development plan with an approach where most of the instruments were built in collaboration with institutions in the member states, with in-kind contributions in labour compensated by guaranteed observing time." Sitting atop the 2600m high Paranal Mountain in the Chilean Atacama Desert, the VLT's design, suite of instruments, and operating principles set the standard for ground-based astronomy. It provides the European scientific community with a telescope array with collecting power significantly greater than any other facilities available at present, offering imaging and spectroscopy capabilities at visible and infrared wavelengths. Blue Flash at Paranal ESO PR Photo 16b/08 A Universe of Discoveries The first scientifically useful images, marking the official 'First Light' of the VLT, were obtained on the night of 25 to 26 May 1998, with a test camera attached to "Antu", Unit Telescope number 1. They were officially presented to the press on the 27 May, exactly ten years ago. Since then, all four Unit Telescopes and four Auxiliary Telescopes went into routine operations and the number of instruments has continued to grow, to fill all the possible positions in the telescopes where instruments can be attached. In 2007, about 500 peer-reviewed papers using data collected with VLT and VLTI instruments at Paranal were published in scientific journals. Since the start of science operations, in April 1999, the VLT has led to the publication of more than 2200 refereed papers, an average of about one paper published every single working day. "The combination of high operational efficiency, system reliability and uptime for scientific observations results in very high scientific productivity," says Andreas Kaufer, director of the La Silla Paranal Observatory. The VLT and VLTI have contributed to all areas of astronomy, including the nature of dark matter and dark energy; the extreme physics of gamma-ray bursts and supernovae; the formation, structure and evolution of galaxies; the properties of exoplanets, Solar System objects, star clusters and stellar populations, the interstellar and intergalactic medium, and of super-massive black holes in galactic nuclei, in particular the one in the Galactic Centre; and the formation of stars and planets. The stunning scientific success of the VLT has attracted new member states to ESO. In the past decade Portugal joined (in 2001, after a ten-year associate status), followed by the United Kingdom (2002), Finland (2004), Spain (2006) and the Czech Republic (2007). Austria also announced its intent to join later this year. Another measure of success is the number of observing proposals made every year for the use of the VLT, which is now above the 1900 mark. On average, the amount of time requested to use the VLT is 6 times higher than what is available. The VLT will continue to increase in power over the next decade. The first of the second-generation VLT instruments, X-Shooter, will come online this year, with KMOS, SPHERE and MUS

2008-05-01

475

Silicon-Web-Growing Machine  

NASA Technical Reports Server (NTRS)

Silicon replenished automatically as web is withdrawn. Semiautomatic silicon-web-growing machine set down in detailed engineering drawings. Melt level sensed with He/Ne laser beam and melt-level error signal used to control motor-driven pellet feeder, speeding up when level is low. System reduces demand upon operator's time.

Duncan, C.

1985-01-01

476

Making Machines See Roberto Cipolla  

E-print Network

Introduction #12;How to make machines that see? #12;Why not study biology? #12;Perspective #12;Transformations models #12;Multiview photometric stereo Vogiatzis, Hernandez and Cipolla 2006 and 2008 #12;Untextured;Deformable objects: Real-time photometric stereo using colour lighting Hernandez et al 2007 #12;Photometric

Cipolla, Roberto

477

The Rise of Machine Intelligence  

Microsoft Academic Search

This paper provides a brief historical introduction to the machine intelligence endeavour, and to the discipline of artificial intelligence (AI) whose techniques are employed in building intelligent software systems. It also presents some AI success stories both outside and within BT.

Hyacinth S. Nwana; Nader Azarmi; R. Smith

1997-01-01

478

Electrical discharge machining in dentistry.  

PubMed

A brief history of electrical discharge machining (EDM) is given and the process is discussed. A description of the application of EDM for fabricating precision attachment removable partial dentures, fixed-removable implant prostheses, and titanium-ceramic crowns is presented. The advantages and disadvantages of the EDM process for the dental profession are evaluated. Although expensive, the procedure has merit. PMID:1524631

Van Roekel, N B

1992-01-01

479

Training Invariant Support Vector Machines  

Microsoft Academic Search

Practical experience has shown that in order to obtain the best possible performance, prior knowledge about invariances of a classification problem at hand ought to be incorporated into the training procedure. We describe and review all known methods for doing so in support vector machines, provide experimental results, and discuss their respective merits. One of the significant new results reported

Dennis Decoste; Bernhard Schölkopf

2002-01-01

480

Hebrew to English Machine Translation  

Microsoft Academic Search

We describe a hybrid transfer-based system for Hebrew to English Machine Translation. This task is particularly challenging due to two reasons: the high lexical and morphological ambiguity of Hebrew and the dearth of available resources for the language. We have used existing, publicly available resources which we adapted for this task. The system is based on a transfer engine which

Yaniv Eytani; Alon Lavie; Erik Peterson; Kathrin Probst; Shuly Wintner

481

Nonabrasive ultrasonic machining of ceramics  

Microsoft Academic Search

The essence of the method includes heating and melting of the blank matelial in the contact zone with a tool and also removal of the machined material. The process is determined mainly by the effect of the energy of ultrasonic vibrations. Blanks of an aluminum oxide ceramic mass with binder content of 14%,* produced by the hot pressure casting method,

Yu. A. Kurdin; A. S. Smirnov; I. I. Polyakov; N. I. Vertokhvostova

1982-01-01

482

Emerging systems and machine intelligence  

SciTech Connect

A theory of mind or intelligence that derives from elements of philosophical, biological, linguistic, and psychological thought as well as of physics and information theory is presented. The hypothesis is defended that intelligence is not a thing but a composite of activities and attributes that must be described in terms of the evolution and interactions of systems, emerging into the environments in which they are embedded. It is proposed that a machine intelligence that emulates human intelligence must conform to certain restrictions that derive from accepting this hypothesis. In particular an implication is that for machine intelligence to be accepted as human-like intelligence it must be produced by a machine that functions in a manner substantially similar to a man and that interacts, grows or learns in and with an environment similar to that in which a man grows and learns. It is proposed that it should be possible to create machines and programs capable of this and that they can achieve intelligence with a large, but not arbitrarily large, degree of human-like characteristics. One system (of many possible systems), in development, based on grammars, and that satisfies some of those requirements is described. It consists of an artificial environment in which a grammar like program based on augmented transition networks, interacts with a human teacher. The purpose of KARA is to learn about the environment by being told and by imitation.

Glasgow, J.C. II.

1989-01-01

483

Description of the Scenario Machine  

E-print Network

We present here an updated description of the "Scenario Machine" code. This tool is used to carry out a population synthesis of binary stars. Previous version of the description can be found at http://xray.sai.msu.ru/~mystery//articles/review/contents.html

V. M. Lipunov; K. A. Postnov; M. E. Prokhorov; A. I. Bogomazov

2007-09-26

484

Analytical design of intelligent machines  

NASA Technical Reports Server (NTRS)

The problem of designing 'intelligent machines' to operate in uncertain environments with minimum supervision or interaction with a human operator is examined. The structure of an 'intelligent machine' is defined to be the structure of a Hierarchically Intelligent Control System, composed of three levels hierarchically ordered according to the principle of 'increasing precision with decreasing intelligence', namely: the organizational level, performing general information processing tasks in association with a long-term memory; the coordination level, dealing with specific information processing tasks with a short-term memory; and the control level, which performs the execution of various tasks through hardware using feedback control methods. The behavior of such a machine may be managed by controls with special considerations and its 'intelligence' is directly related to the derivation of a compatible measure that associates the intelligence of the higher levels with the concept of entropy, which is a sufficient analytic measure that unifies the treatment of all the levels of an 'intelligent machine' as the mathematical problem of finding the right sequence of internal decisions and controls for a system structured in the order of intelligence and inverse order of precision such that it minimizes its total entropy. A case study on the automatic maintenance of a nuclear plant illustrates the proposed approach.

Saridis, George N.; Valavanis, Kimon P.

1987-01-01

485

Optical-Fiber-Welding Machine  

NASA Technical Reports Server (NTRS)

Technique yields joints with average transmissivity of 91.6 percent. Electric arc passed over butted fiber ends to melt them together. Maximum optical transmissivity of joint achieved with optimum choice of discharge current, translation speed, and axial compression of fibers. Practical welding machine enables delicate and tedious joining operation performed routinely.

Goss, W. C.; Mann, W. A.; Goldstein, R.

1985-01-01

486

Machine Translation: Developments and Prospects.  

ERIC Educational Resources Information Center

Examines the history and resurgence of machine translation, describing metalanguages and transfer languages as algorithms for transforming source languages into target languages and reviewing prospects for the future. Indicates that leadership in this field is held by Japan for both hardware and software development for Japanese/English…

Russell, Robert A.

1985-01-01

487

Semantic Analysis in Machine Translation.  

ERIC Educational Resources Information Center

In many cases machine-translation does not produce satisfactory results within the framework of purely formal (morphological and syntaxic) analysis, particularly, in the case of syntaxic and lexical homonomy. An algorithm for syntaxic-semantic analysis is proposed, and its principles of operation are described. The syntaxico-semantic structure is…

Skorokhodko, E. F.

1970-01-01

488

Machine Translation for Academic Purposes  

ERIC Educational Resources Information Center

Due to the globalization trend and knowledge boost in the second millennium, multi-lingual translation has become a noteworthy issue. For the purposes of learning knowledge in academic fields, Machine Translation (MT) should be noticed not only academically but also practically. MT should be informed to the translating learners because it is a…

Lin, Grace Hui-chin; Chien, Paul Shih Chieh

2009-01-01

489

Confldence Estimation for Machine Translation  

Microsoft Academic Search

We present a detailed study of confldence esti- mation for machine translation. Various meth- odsfordeterminingwhetherMToutputiscor- rect are investigated, for both whole sentences andwords. Sincethenotionofcorrectnessisnot intuitively clear in this context, difierent ways of deflning it are proposed. We present results ondatafromtheNIST2003Chinese-to-English MT evaluation.

John Blatz; Erin Fitzgerald; George Foster; Simona Gandrabur; Alex Kulesza; Alberto Sanchis; Nicola Ue-ng; RWTH Aachen

2003-01-01

490

Machine Learning of Jazz Grammars  

E-print Network

Machine Learning of Jazz Grammars Jon Gillick, Kevin Tang, and Robert M. Keller Annkissam One novel jazz solos using a probabilistic grammar (Keller 2007), this article describes the automated into the grammar. This article first defines the basic building blocks for contours of typical jazz solos, which we

Li, Fei-Fei

491

Machinability study of Aermet 100  

Microsoft Academic Search

Machinability of Aermet 100, an ultrahigh strength alloy developed for Navy by Carpenter Technology as a candidate material for aircraft landing gear application, was studied by performing single-point turning tests. Coated and uncoated carbides, ceramic, and cermet cutting tool inserts of a square geometry (SNG 432 type) were used. Round stock workpieces were tested in the as - received, unaged

D. V. Squire; C. K. Syn; B. L. Fix

1995-01-01

492

Miniature Gas-Circulating Machine  

NASA Technical Reports Server (NTRS)

Proposed gas-circulating machine consists essentially of centrifugal pump driven by induction motor. Noncontact bearings suppress wear and contamination. Used to circulate helium (or possibly hydrogen or another gas) in regeneration sorption-compressor refrigeration system aboard spacecraft. Also proves useful in terrestrial applications in which long life, reliability, and low contamination essential.

Swift, Walter L.; Valenzuela, Javier A.; Sixsmith, Herbert; Nutt, William E.

1993-01-01

493

Ultrashort-pulse lasers machining  

SciTech Connect

A new type of material processing is enabled with ultrashort (t < 10 psec) laser pulses. Cutting, drilling, sculpting of all materials (biologic materials, ceramics, sapphire, silicon carbide, diamond, metals) occurs by new mechanisms which eliminate thermal shock or collateral damage. High precision machining to submicron tolerances is enabled resulting in high surface quality and negligible heat affected zone.

Banks, P S; Feit, M D; Nguyen, H T; Perry, M D, Stuart, B C

1999-01-22

494

Workpiece fixturing for precision machining  

SciTech Connect

To keep within the tolerances required in precision machining workpiece fixturing has to ensure minimal distortion of the part. Some of the methods used at the Oak Ridge Y-12 Plant are reviewed. Significant factors are discussed and three-point mounting, vacuum fixturing and potting are described.

Barkman, W.E.

1982-04-01

495

Molecular machines: Springing into action  

Microsoft Academic Search

Controlling the movements of molecular systems through external stimuli is crucial for the construction of nanoscale mechanical machines. A spring-like compound has now been prepared - a double helicate that retains its handedness under ion-triggered extension and contraction.

Ben L. Feringa

2010-01-01

496

Piston for dry crankcase machines  

Microsoft Academic Search

There are several problems when such machines are operated in an inert gas medium. The major problem is at the joint between the pin and the bearing. The pin surface gets damaged because of the small rocking angle (less than the angle between adjacent needles), high .contact pressures (above 104 MPa), and comparatively large rocking frequency. Increasing the hardness of

A. V. Borodin; N. Kh. Khamitov

1990-01-01

497

Com1005 Machines and Intelligence  

E-print Network

Com1005 Machines and Intelligence Lecturers: Dr Amanda Sharkey, Professor Phil Green Monday, 1 October 2012 #12;What is Artificial Intelligence? Monday, 1 October 2012 #12;What is Artificial Intelligence? · "Artificial Intelligence (AI) is the study of intelligent behaviour (in humans, animals

Sharkey, Amanda

498

Teaching Machines to Think Fuzzy  

ERIC Educational Resources Information Center

Fuzzy logic programs for computers make them more human. Computers can then think through messy situations and make smart decisions. It makes computers able to control things the way people do. Fuzzy logic has been used to control subway trains, elevators, washing machines, microwave ovens, and cars. Pretty much all the human has to do is push one…

Technology Teacher, 2004

2004-01-01

499

Simple Machines in the Community  

ERIC Educational Resources Information Center

The community can be a powerful context and mini-laboratory for cultivating students' common understandings of science and mathematics. On the island of Panay in the Philippines, the community was the starting place for a group of fifth- and sixth-grade students to explore simple machines in their daily lives. What students learned in the process…

Bryan, Robert; Laroder, Aris; Tippins, Deborah; Emaz, Meliza; Fox, Ryan

2008-01-01

500

Far Travelers: The Exploring Machines.  

ERIC Educational Resources Information Center

The National Aeronautics and Space Administration (NASA) program of lunar and planetary exploration produced a flood of scientific information about the moon, planets and the environment of interplanetary space. This book is an account of the people, machines, and the events of this scientific enterprise. It is a story of organizations,…

Nicks, Oran W.