Pulkkinen, Lea; Latvala, Antti; Rose, Richard J
We offer a brief sketch of an overlooked early twin researcher, Arvo Johannes Lehtovaara (1905-1985), Professor of Psychology at the University of Jyväskylä, 1939-1952, and the University of Helsinki, 1952-1970, with background notes on his mentor, Eino Kaila. PMID:26996224
Buša, Ján; Hayryan, Shura; Wu, Ming-Chya; Buša, Ján; Hu, Chin-Kun
Introduction of Graphical Processing Units (GPUs) and computing using GPUs in recent years opened possibilities for simple parallelization of programs. In this update, we present the modernized version of program ARVO [J. Buša, J. Dzurina, E. Hayryan, S. Hayryan, C.-K. Hu, J. Plavka, I. Pokorný, J. Skivánek, M.-C. Wu, Comput. Phys. Comm. 165 (2005) 59]. The whole package has been rewritten in the C language and parallelized using OpenCL. Some new tricks have been added to the algorithm in order to save memory much needed for efficient usage of graphical cards. A new tool called ‘input_structure’ was added for conversion of pdb files into files suitable for work with the C and OpenCL version of ARVO.
Sullivan, David A; Hammitt, Katherine M; Schaumberg, Debra A; Sullivan, Benjamin D; Begley, Carolyn G; Gjorstrup, Per; Garrigue, Jean-Sébastien; Nakamura, Masatsugu; Quentric, Yann; Barabino, Stefano; Dalton, Michelle; Novack, Gary D
In September 2010, a Symposium in Florence, Italy, was held to address the unmet need for global treatments for dry eye disease (DED). It was sponsored by The Tear Film & Ocular Surface Society (TFOS; www.TearFilm.org) and co-sponsored by the Association for Research in Vision & Ophthalmology (www.arvo.org). The Symposium objectives were two-fold: first, to discuss accepted and emerging clinical endpoints of DED with regulatory experts from around the world; and second, to consider how to improve clinical trials of treatments for DED. The Symposium focused on the personal and collective burden of DED, as well as the developmental and regulatory challenges associated with generating new DED therapeutics. This article provides a synopsis of many of the presentations, discussions and recommendations of this Symposium. PMID:22482471
The 2010 Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO), held in Fort Lauderdale, FL, USA, included topics covering new therapeutic developments in the field of eye and vision research. This conference report highlights selected presentations on the development of OT-440 (Othera Pharmaceuticals Inc) for the potential treatment of glaucoma, an extended-release implant of brimonidine (pSivida Corp) for ocular hypertension, AR-12286 (Aerie Pharmaceuticals Inc) for ocular hypertension or glaucoma, AC-8 (Calmune Corp/RiboVax Biotechnologies SA) for ocular diseases following HSV infection, and fidarestat (Sanwa Kagaku Kenkyusho Co Ltd) and the recombinant proteins NOV and NOVCter (INSERM/University Rene Descartes) for corneal neovascularization. PMID:20582863
... HUMAN SERVICES Centers for Disease Control and Prevention Advisory Committee on Immunization Practices...; Pertussis vaccine; Influenza vaccines; the 2011 Immunization Schedule for adults, children & adolescents... Person for More Information: Leola Mitchell, National Center for Immunization and Respiratory...
O'Donnell, Sheryl, Ed.; Shaver, Barbara, Ed.
Articles on women's studies and females in higher education are presented in this publication. A University of North Dakota project that sought to promote the integration of new research and scholarship results into the curriculum is described in "Women's Equity Committee Offers a Model Project," (Leola Furman, Robert Young). Historical…
Mickaelian, A. M.; Astsatryan, H. V.; Knyazyan, A. V.; Magakian, T. Yu.; Mikayelyan, G. A.; Erastova, L. K.; Hovhannisyan, L. R.; Sargsyan, L. A.; Sinamyan, P. K.
Armenian Virtual Observatory (ArVO, www.aras.am/Arvo/arvo.htm) was created 10 years ago, in 2005, when after the accomplishment of the Digitized First Byurakan Survey (DFBS, www.aras.am/Dfbs/dfbs.html) we had enough resources to run a VO project and contribute in the International Virtual Observatory Alliance (IVOA, www.ivoa.net). ArVO is a project of Byurakan Astrophysical Observatory (BAO) aimed at construction of a modern system for data archiving, extraction, acquisition, reduction, use and publication. ArVO technical and research projects include Global Spectroscopic Database, which is being built based on DFBS. Quick optical identification of radio, IR or X-ray sources will be possible by plotting their positions in the DFBS or other spectroscopic plate and matching all available data. Accomplishment of new projects by combining data is so important that the International Council of Scientific Unions (ICSU) recently created World Data System (WDS, www.icsu-wds.org/) for unifying data coming from all science areas, and BAO has also joined it due to DFBS and ArVO projects.
Knyazyan, A. V.; Astsatryan, H. V.; Mickaelian, A. M.
The main aim of this article is to introduce the data management and services of the Armenian Virtual Observatory (ArVO), which consists of user friendly data management mechanisms, a new and productive cross-correlation service, and data sharing API based on international standards and protocols.
Carpenter, Don A., Ed.
This annual collection of articles on teaching and learning in Utah's 2-year colleges begins with an examination by Don A. Carpenter of the slow growth and acceptance of the comprehensive concept of the community college prevalent in other states. Next, Arvo Van Alstyne discusses "Educational Purposes and Priorities" and argues for a diversified…
Mickaelian, A. M.
A report is given on the achievements of the Armenian astronomy during the last years and on the present activities of the Armenian Astronomical Society (ArAS). ArAS membership, ArAS electronic newsletters (ArASNews), ArAS webpage, international collaboration, Armenian Virtual Observatory (ArVO), membership in international organizations, grants, prizes, meetings, summer schools, astronomical Olympiads, other matters related to astronomical education, archaeoastronomy, astronomy outreach and ArAS further projects are discussed.
Mickaelian, A. M.
Vast amount of information continuously accumulated in astronomy requires finding new solutions for its efficient storage, use and dissemination, as well as accomplishing new research projects. Virtual Observatories (VOs) have been created in a number of countries to set up a new environment for these tasks. Based on them, the International Virtual Observatory Alliance (IVOA) was created in 2002, which unifies 19 VO projects, including Armenian Virtual Observatory (ArVO) founded in 2005. ArVO is a project of Byurakan Astrophysical Observatory (BAO) aimed at construction of a modern system for data archiving, extraction, acquisition, reduction, use and publication. ArVO technical and research projects are presented, including the Global Spectroscopic Database, which is being built based on Digitized First Byurakan Survey (DFBS). Quick optical identification of radio, IR or X-ray sources will be possible by plotting their positions in the DFBS or other spectroscopic plate and matching all available data. Accomplishment of new projects by combining data is so important that the International Council of Scientific Unions (ICSU) recently created World Data System (WDS) for unifying data coming from all science areas, and BAO has also joined it.
Mickaelian, A. M.; Abrahamyan, H. V.; Paronyan, G. M.; Harutyunyan, G. S.
Markarian galaxies are the result of the First Byurakan Survey (FBS) conducted in 1965-1980 by B.E. Markarian et al. The sample consists of 1515 UV-excess galaxies containing many active galaxies, both AGN and starburst (SB) galaxies that are interesting from the point of view of galaxy evolution and multiwavelength studies. Several catalogs of Markarian galaxies have been published; however, multiwavelength (MW) data were not provided and matched for more efficient investigations. Moreover, SDSS spectra now give possibility for better classification by activity types, and we have accomplished fine classification obtaining new types and subtypes for most of the objects. We have cross-correlated the Markarian catalogue with all available large-area MW catalogues at various wavelengths, from X-ray to radio: ROSAT BSC and FSC, GALEX, APM, MAPS, USNO B1.0, GSC 2.3.2, SDSS, 2MASS PSC and ESC, WISE, AKARI-IRC, IRAS PSC, FSC, and SSSC, AKARI-FIS, GB6, NVSS, FIRST, SUMSS, WENSS, and 7C providing 35 photometric data-points, as well as the Digitized FBS (DFBS, http://byurakan.phys.uniroma1.it/) and Hamburg Quasar Survey (HQS) low-dispersion spectra. The Armenian Virtual Observatory (ArVO, http://www.aras.am/Arvo/arvo.htm) services have been used for cross-correlations and extraction of DFBS spectra; MW SEDs have been built using the IVOA tools, and MW classification has been accomplished. Diagrams with MW flux ratios have been built to reveal objects with extreme characteristics. The classifications have been matched with these flux ratios. A MW catalog of Markarian galaxies has been compiled.
The Byurakan Astrophysical Observatory (BAO, Armenia, http://www.bao.am) are among the candidate IAU Regional Nodes for Astronomy for Development activities. It is one of the main astronomical centers of the former Soviet Union and the Middle East region. At present there are 48 qualified researchers at BAO, including six Doctors of Science and 30 PhDs. Five important observational instruments are installed at BAO, the larger ones being 2.6m Cassegrain (ZTA-2.6) and 1m Schmidt (the one that provided the famous Markarian survey). BAO is regarded as a national scientific-educational center, where a number of activities are being organized, such as: international conferences (4 IAU symposia and 1 IAU colloquium, JENAM-2007, etc.), small workshops and discussions, international summer schools (1987, 2006, 2008 and 2010), and Olympiads. BAO collaborates with scientists from many countries. The Armenian Astronomical Society (ArAS, http://www.aras.am/) is an NGO founded in 2001; it has 93 members and it is rather active in the organization of educational, amateur, popular, promotional and other matters. The Armenian Virtual Observatory (ArVO, http://www.aras.am/Arvo/arvo.htm) is one of the 17 national VO projects forming the International Virtual Observatories Alliance (IVOA) and is the only VO project in the region serving also for educational purposes. A number of activities are planned, such as management, coordination and evaluation of the IAU programs in the area of development and education, establishment of the new IAU endowed lectureship program and organization of seminars and public lectures, coordination and initiation of fundraising activities for astronomy development, organization of regional scientific symposia, conferences and workshops, support to Galileo Teacher Training Program (GTTP), production/publication of educational and promotional materials, etc.
Beutter, B. R.; Mulligan, J. B.; Stone, L. S.; Hargens, Alan R. (Technical Monitor)
We have shown that moving a plaid in an asymmetric window biases the perceived direction of motion (Beutter, Mulligan & Stone, ARVO 1994). We now explore whether these biased motion signals might also drive the smooth eye-movement response by comparing the perceived and tracked directions. The human smooth oculomotor response to moving plaids appears to be driven by the perceived rather than the veridical direction of motion. This suggests that human motion perception and smooth eye movements share underlying neural motion-processing substrates as has already been shown to be true for monkeys.
Battu, Rajani; Dabir, Supriya; Khanna, Anjani; Kumar, Anupama Kiran; Roy, Abhijit Sinha
Adaptive optics is a relatively new tool that is available to ophthalmologists for study of cellular level details. In addition to the axial resolution provided by the spectral-domain optical coherence tomography, adaptive optics provides an excellent lateral resolution, enabling visualization of the photoreceptors, blood vessels and details of the optic nerve head. We attempt a mini review of the current role of adaptive optics in retinal imaging. PubMed search was performed with key words Adaptive optics OR Retina OR Retinal imaging. Conference abstracts were searched from the Association for Research in Vision and Ophthalmology (ARVO) and American Academy of Ophthalmology (AAO) meetings. In total, 261 relevant publications and 389 conference abstracts were identified. PMID:24492503
Feke, G T
The theory underlying the development of laser Doppler instrumentation for the measurement of retinal blood flow is framed in terms of (a) the enunciation of the Doppler principle; (b) the invention of the laser; and (c) the invention of the technique known as optical mixing spectroscopy. The features of the instrumentation, beginning with the first prototype in 1972 and culminating with the introduction of the Canon Laser Blood Flowmeter in 1998 are presented in detail. Results from seven separate studies reporting on the reproducibility of retinal blood flow measurements using the Canon instrument, as well as a review of 12 separate presentations made at the 2004 annual meeting of the Association for Research in Vision and Ophthalmology (ARVO) using the Canon instrument in studies involving retinal circulatory physiology and associated clinical research are also presented. PMID:17265797
Background The inclusion of randomized controlled trials (RCTs) reported in conference abstracts in systematic reviews is controversial, partly because study design information and risk of bias is often not fully reported in the abstract. The Association for Research in Vision and Ophthalmology (ARVO) requires trial registration of abstracts submitted for their annual conference as of 2007. Our goal was to assess the feasibility of obtaining study design information critical to systematic reviews, but not typically included in conference abstracts, from the trial registration record. Methods We reviewed all conference abstracts presented at the ARVO meetings from 2007 through 2009, and identified 496 RCTs; 154 had a single matching registration record in ClinicalTrials.gov. Two individuals independently extracted information from the abstract and the ClinicalTrials.gov record, including study design, sample size, inclusion criteria, masking, interventions, outcomes, funder, and investigator name and contact information. Discrepancies were resolved by consensus. We assessed the frequencies of reporting variables appearing in the abstract and the trial register and assessed agreement of information reported in both sources. Results We found a substantial amount of study design information in the ClinicalTrials.gov record that was unavailable in the corresponding conference abstract, including eligibility criteria associated with gender (83%; 128/154); masking or blinding of study participants (53%, 82/154), persons administering treatment (30%, 46/154), and persons measuring the outcomes (40%, 61/154)); and number of study centers (58%; 90/154). Only 34% (52/154) of abstracts explicitly described a primary outcome, but a primary outcome was included in the “Primary Outcome” field in the ClinicalTrials.gov record for 82% (126/154) of studies. One or more study interventions were reported in each abstract, but agreed exactly with those reported in Clinical
Tahi, Hassan; Chapon, Pascal F.; Hamaoui, Marie; Lee, William E.; Holden, Brien; Parel, Jean-Marie A.
Purpose. To evaluate an innovative surgical technique for phaco-ersatz, a cataract surgery designed to restore accommodation. Techniques for very small capsulorhexis as well as the refilling procedure were developed. This study evaluates the feasibility and reproducibility of the surgical technique. Methods. The right eye of 8 NZW rabbits (~ 2 Kg) were operated following the ARVO Statements for the Use of Animals in Ophthalmic and Vision Research. The surgery is begun by making a small peripheral capsulorhexis of about 1 mm using. The lens content is then removed. The lens is then refilled with a novel in situ polymerizable gel and the corneal incision is closed using one 10/0 Nylon interrupted stitch. Results. The capsulorhexis technique was succesfully performed and reproducible in all animals. The average size of the capsulorhexis opening was 1. 2 mm (+/-0.14). Lens material removal and refilling of the capsular bag with an in situ polymerizable material was also performed in each trial study. Conclusion. This surgical technique seemed feasible and reproducible.
Mickaelian, Areg M.
Astronomical plate archives created on the basis of numerous observations at many observatories are important part of the astronomical heritage. Byurakan Astrophysical Observatory (BAO) plate archive consists of 37,500 photographic plates and films, obtained at 2.6m telescope, 1m and 0.5m Schmidt telescopes and other smaller ones during 1947-1991. In 2002-2005, the famous Markarian Survey (First Byurakan Survey, FBS) 2000 plates were digitized and the Digitized FBS (DFBS, http://www.aras.am/Dfbs/dfbs.html) was created. New science projects have been conducted based on these low-dispersion spectroscopic material. In 2015, we have started a project on the whole BAO Plate Archive digitization, creation of electronic database and its scientific usage. A Science Program Board is created to evaluate the observing material, to investigate new possibilities and to propose new projects based on the combined usage of these observations together with other world databases. The Executing Team consists of 9 astronomers and 3 computer scientists and will use 2 EPSON Perfection V750 Pro scanners for the digitization, as well as Armenian Virtual Observatory (ArVO) database to accommodate all new data. The project will run during 3 years in 2015-2017 and the final result will be an electronic database and online interactive sky map to be used for further research projects.
In the early 1980s the Wellcome Institute was planning a biographical dictionary on the world's most eminent physicians. The quota reserved for Finland was ten names, and having been asked by Dr. Karin Johannisson, Uppsala, to participate in the project, I undertook the task of choosing them and providing a short biography of each. For this, I asked the advice of ten experts on the history of Finnish medicine, and a "top ten" list was then compiled. The list extended from Johan Haartman, "the father of Finnish medicine", till the Nobel Prize winner Ragnar Granit and the famous pediatrist Arvo Ylppo, who were still alive in the 1980s. The biographies were sent to the editor of the dictionary, but it seems that the work was never published. As I had saved all my correspondence about the matter, it seemed now, fifteen years afterwards, interesting to publish a short report of the project, including an account of how the "top ten" list had been achieved. PMID:11625413
Mickaelian, A. M.; Abrahamyan, H. V.; Andreasyan, H. R.; Azatyan, N. M.; Farmanyan, S. V.; Gigoyan, K. S.; Gyulzadyan, M. V.; Khachatryan, K. G.; Knyazyan, A. V.; Kostandyan, G. R.; Mikayelyan, G. A.; Nikoghosyan, E. H.; Paronyan, G. M.; Vardanyan, A. V.
The most important part of the astronomical observational heritage are astronomical plate archives created on the basis of numerous observations at many observatories. Byurakan Astrophysical Observatory (BAO) plate archive consists of 37,000 photographic plates and films, obtained at 2.6m telescope, 1m and 0.5m Schmidt type and other smaller telescopes during 1947-1991. In 2002-2005, the famous Markarian Survey (also called First Byurakan Survey, FBS) 1874 plates were digitized and the Digitized FBS (DFBS) was created. New science projects have been conducted based on these low-dispersion spectroscopic material. A large project on the whole BAO Plate Archive digitization, creation of electronic database and its scientific usage was started in 2015. A Science Program Board is created to evaluate the observing material, to investigate new possibilities and to propose new projects based on the combined usage of these observations together with other world databases. The Executing Team consists of 11 astronomers and 2 computer scientists and will use 2 EPSON Perfection V750 Pro scanners for the digitization, as well as Armenian Virtual Observatory (ArVO) database will be used to accommodate all new data. The project will run during 3 years in 2015-2017 and the final result will be an electronic database and online interactive sky map to be used for further research projects, mainly including high proper motion stars, variable objects and Solar System bodies.
We have used ARVO developed by us to find that the ratio of volume and surface area of proteins in Protein Data Bank distributed in a very narrow region . Such result is useful for the determination of protein 3D structures. It has been widely known that a spin glass model can be used to understand the slow relaxation behavior of a glass at low temperatures . We have used molecular dynamics and simple models of polymer chains to study relaxation and aggregation of proteins under various conditions and found that polymer chains with neighboring monomers connected by rigid bonds can relax very slowly and show glassy behavior . We have also found that native collagen fibrils show glassy behavior at room temperatures . The results of  and  about the glassy behavior of polymers or proteins are useful for understanding the mechanism for a biological system to maintain in a non-equilibrium state, including the ancient seed , which can maintain in a non-equilibrium state for a very long time. (1) M.-C. Wu, M. S. Li, W.-J. Ma, M. Kouza, and C.-K. Hu, EPL, in press (2011); (2) C. Dasgupta, S.-K. Ma, and C.-K. Hu. Phys. Rev. B 20, 3837-3849 (1979); (3) W.-J. Ma and C.-K. Hu, J. Phys. Soc. Japan 79, 024005, 024006, 054001, and 104002 (2010), C.-K. Hu and W.-J. Ma, Prog. Theor. Phys. Supp. 184, 369 (2010); S. G. Gevorkian, A. E. Allahverdyan, D. S. Gevorgyan and C.-K. Hu, EPL 95, 23001 (2011); S. Sallon, et al. Science 320, 1464 (2008).
Mickaelian, A. M.; Astsatryan, H. V.; Sahakyan, V. G.; Sargsyan, L. A.; Nesci, R.; Cirimele, G.; Harutyunian, H. A.; Magakian, T. Yu.; Sinamyan, P. K.; Mikayelyan, G. A.
The Digitized First Byurakan Survey (DFBS) is the digitized version of the famous Markarian Survey, also known as the First Byurakan Survey (FBS). It is the largest low dispersion spectroscopic survey of the sky covering 17,000 square degrees at galactic latitudes |b|>15(o) . DFBS provides the astronomical community with images and extracted spectra for all objects present in the FBS plates. Some 1800 plates have been scanned and stored and programs were developed to compute the astrometric solution, extract the spectra, and apply wavelength and photometric calibration for the objects. The DFBS database and catalog have been assembled containing data for nearly 20,000,000 objects. A classification scheme for the DFBS spectra is being developed. DFBS has been installed on dedicated servers at Univerista di Roma ``La Sapienza" (Italy) and at present on the ArmCluster at the Institute for Informatics and Automation Problems (Armenia). A work is active on making the DFBS available through the Virtual Observatory standards and access to spectroscopic data. From the point of view of VO, the DFBS is a new database needing both image and spectra access tools and an interchange between these two standards. Algorithms, tools, and facilities needed for efficient use of the DFBS are discussed, in particular the spectra extraction, visualization, and analysis tools. New scientific projects as well as existing surveys will benefit by the digitized images and the ready-to-use extracted spectra which will allow an efficient computer-based analysis of the dataset. The Armenian Virtual Observatory (ArVO) is based on the DFBS database and other large-area surveys and catalogue data and is a part of the International Virtual Observatory Alliance (IVOA).
Mickaelian, A. M.
Astronomy in Armenia was popular since ancient times. There are signs of astronomical observations coming from a few thousands years ago. Two ancient observatories, Karahunge and Metzamor are especially well known. Karahunge is the Armenian twin of the Stonehenge and is even older. However, there is no proper attention from the state authorities and efforts are needed for preservation of such historical-astronomical monuments. The Byurakan Astrophysical Observatory (BAO) is the modern famous Armenian observatory founded in 1946 by the outstanding scientist Victor Ambartsumian. It was one of the world astronomical centres in 1950-s to 1970-s, and at present is the largest observatory in the Middle East area. As the ancient astronomical sites, Byurakan also needs a proper attitude from the state authorities and corresponding international organizations to preserve its values and importance for the present and future astronomical activities in the region, including its rich observational archive, telescopes, and human resources. Despite all the difficulties, the Armenian astronomers keep high international level of research and display various activities organizing international meetings and schools, preparing new young generation for the future research. The Armenian Astronomical Society (ArAS) is an affiliated member of EAS. Armenia has its Virtual Observatory project (ArVO) as well. The next Joint European and National Astronomy Meeting (JENAM-2007) will be held in Yerevan, Armenia, in August 2007. There are plans to organize astronomical tours to Armenia for making observations from various sites, including the ancient observatories. The future of astronomy in Armenia strongly depends on all of this activities and the proper attention both from state authorities and society.
Nõmmiste, Ergo; Kirm, Marco; Plank, Toomas
oral, and 5 commercial talks were delivered and more than 200 posters were presented. In the framework of conference more than 20 papers were submitted to a topical issue of Physica Scripta. Based on the work presented at the conference, 62 articles are included in this volume of IOP Conference Series: Materials Science and Engineering. Additional information about FM&NT-2013 is available at its homepage http://fmnt.ut.ee/. The Organizing Committee would like to thank all the speakers, contributors, session chairs, referees and other involved staff for their efforts in making FM&NT-2013 successful. Special thanks for their hard work dealing with the conference papers goes to the Guest Editors: Professor Mikhail Brik, Dr Svetlana Zazubovits, Dr Arvo Kikas, Dr Rainer Pärna. The Organizing Committee hopes that Conference gave participants good insight into recent developments in nanotechnology, sustainable energetics, processing and modelling of multifunctional materials and research done using synchrotron radiation or other novel light sources. We sincerely hope that conference has provided support for the sharing of information and has brought together many young and experienced scientists from different fields, leading to fruitful discussions. We hope that all participants had good and memorable time in Tartu. On the behalf of organising committee Professor Ergo Nõmmiste Dr Marco Kirm Dr Toomas Plank The PDF also contains lists of the committees, the conference photograph and the sponsor's logos.